locus-tag	class	description
FGM04_00005	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_00005	COG1454	alcohol dehydrogenase
FGM04_00010	COG2095	MarC family integral membrane protein
FGM04_00020	COG0601	transmembrane transport
FGM04_00025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGM04_00030	COG0444	Belongs to the ABC transporter superfamily
FGM04_00040	COG0861	Integral membrane protein TerC family
FGM04_00045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGM04_00075	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FGM04_00085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_00090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGM04_00095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGM04_00100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FGM04_00105	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FGM04_00120	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FGM04_00125	COG0505	Belongs to the CarA family
FGM04_00130	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FGM04_00180	COG0346	lactoylglutathione lyase activity
FGM04_00185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FGM04_00195	COG4659	FMN binding
FGM04_00200	COG4658	electron transport chain
FGM04_00210	COG2878	Part of a membrane complex involved in electron transport
FGM04_00215	COG4657	Part of a membrane complex involved in electron transport
FGM04_00220	COG1061	Type III restriction enzyme res subunit
FGM04_00230	COG0346	lactoylglutathione lyase activity
FGM04_00240	COG0583	DNA-binding transcription factor activity
FGM04_00250	COG0840	transmembrane signaling receptor activity
FGM04_00255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FGM04_00260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGM04_00265	COG2271	Major facilitator Superfamily
FGM04_00270	COG1349	DNA-binding transcription factor activity
FGM04_00280	COG0584	glycerophosphoryl diester phosphodiesterase
FGM04_00285	COG4574	serine-type endopeptidase inhibitor activity
FGM04_00290	COG3085	chromosome segregation
FGM04_00295	COG0583	DNA-binding transcription factor activity
FGM04_00305	COG1448	Aminotransferase
FGM04_00320	COG2333	competence protein COMEC
FGM04_00320	COG0658	competence protein
FGM04_00330	COG1663	tetraacyldisaccharide 4'-kinase activity
FGM04_00335	COG2835	tetraacyldisaccharide 4'-kinase activity
FGM04_00340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FGM04_00345	COG2197	response regulator
FGM04_00350	COG0322	excinuclease ABC activity
FGM04_00375	COG0582	viral genome integration into host DNA
FGM04_00420	COG4869	propanediol catabolic process
FGM04_00425	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FGM04_00430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_00435	COG1882	Formate acetyltransferase
FGM04_00440	COG1454	alcohol dehydrogenase
FGM04_00440	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_00450	COG1454	alcohol dehydrogenase
FGM04_00450	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_00455	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FGM04_00460	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FGM04_00465	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FGM04_00485	COG1349	DNA-binding transcription factor activity
FGM04_00490	COG2084	Dehydrogenase
FGM04_00500	COG3039	Transposase
FGM04_00520	COG0235	Class ii aldolase
FGM04_00550	COG2801	Transposase and inactivated derivatives
FGM04_00580	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_00590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGM04_00595	COG0215	cysteine-tRNA ligase activity
FGM04_00600	COG0210	DNA helicase
FGM04_00605	COG3039	Transposase
FGM04_00640	COG2119	membrane
FGM04_00645	COG0023	Translation Initiation Factor
FGM04_00670	COG0513	Belongs to the DEAD box helicase family
FGM04_00685	COG0493	'glutamate synthase
FGM04_00690	COG0069	glutamate synthase activity
FGM04_00690	COG0070	glutamate synthase
FGM04_00690	COG0067	glutamate synthase
FGM04_00695	COG1242	4 iron, 4 sulfur cluster binding
FGM04_00735	COG1464	Belongs to the NlpA lipoprotein family
FGM04_00740	COG3083	sulfuric ester hydrolase activity
FGM04_00745	COG3082	Protein of unknown function (DUF1414)
FGM04_00750	COG3081	Nucleoid-associated protein
FGM04_00760	COG1175	transmembrane transport
FGM04_00770	COG3842	ATPase activity
FGM04_00795	COG0425	Belongs to the sulfur carrier protein TusA family
FGM04_00800	COG4783	chaperone-mediated protein folding
FGM04_00810	COG1393	Belongs to the ArsC family
FGM04_00820	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FGM04_00830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_00835	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGM04_00840	COG2431	L-lysine efflux transmembrane transporter activity
FGM04_00850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_00855	COG4215	(ABC) transporter
FGM04_00860	COG4160	amino acid transport
FGM04_00865	COG0564	pseudouridine synthase activity
FGM04_00880	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FGM04_00890	COG0625	glutathione transferase activity
FGM04_00930	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGM04_00960	COG0367	asparagine synthase
FGM04_00970	COG4651	solute:proton antiporter activity
FGM04_00970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FGM04_00975	COG0647	UMP catabolic process
FGM04_00980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGM04_00990	COG1902	pentaerythritol trinitrate reductase activity
FGM04_00995	COG1253	flavin adenine dinucleotide binding
FGM04_01005	COG0277	FAD linked oxidase domain protein
FGM04_01005	COG0247	lactate metabolic process
FGM04_01015	COG2050	protein possibly involved in aromatic compounds catabolism
FGM04_01025	COG2056	Na+-H+ antiporter family
FGM04_01030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGM04_01035	COG0671	phosphoesterase, PA-phosphatase related
FGM04_01040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGM04_01045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGM04_01055	COG0101	tRNA pseudouridine synthase activity
FGM04_01060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FGM04_01065	COG0285	dihydrofolate synthase activity
FGM04_01070	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FGM04_01075	COG0393	Putative heavy-metal-binding
FGM04_01085	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGM04_01085	COG1648	precorrin-2 dehydrogenase activity
FGM04_01090	COG2221	Nitrite and sulphite reductase 4Fe-4S
FGM04_01105	COG4667	esterase of the alpha-beta hydrolase superfamily
FGM04_01110	COG1619	proteins homologs of microcin C7 resistance protein MccF
FGM04_01115	COG1368	sulfuric ester hydrolase activity
FGM04_01125	COG0527	aspartate kinase activity
FGM04_01130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGM04_01130	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FGM04_01135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FGM04_01155	COG0596	Alpha beta hydrolase
FGM04_01180	COG1136	(ABC) transporter
FGM04_01195	COG2814	Major facilitator Superfamily
FGM04_01220	COG0672	)-iron permease
FGM04_01240	COG0514	ATP-dependent DNA helicase (RecQ)
FGM04_01265	COG0659	secondary active sulfate transmembrane transporter activity
FGM04_01280	COG4974	Belongs to the 'phage' integrase family
FGM04_01285	COG3039	Transposase
FGM04_01320	COG3039	Transposase
FGM04_01375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FGM04_01375	COG0392	lysyltransferase activity
FGM04_01385	COG2205	protein histidine kinase activity
FGM04_01390	COG0745	RESPONSE REGULATOR receiver
FGM04_01410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FGM04_01415	COG1278	Cold shock
FGM04_01420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FGM04_01425	COG0542	response to heat
FGM04_01430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FGM04_01435	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FGM04_01440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FGM04_01445	COG3134	Outer membrane lipoprotein
FGM04_01450	COG3706	GGDEF domain
FGM04_01455	COG0492	ferredoxin-NADP+ reductase activity
FGM04_01460	COG0686	Belongs to the AlaDH PNT family
FGM04_01470	COG0531	amino acid
FGM04_01470	COG1674	ftsk spoiiie
FGM04_01475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FGM04_01480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FGM04_01485	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FGM04_01490	COG1286	toxin biosynthetic process
FGM04_01495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FGM04_01505	COG0563	adenylate kinase activity
FGM04_01510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FGM04_01520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_01535	COG5001	Diguanylate cyclase
FGM04_01535	COG3300	MHYT domain
FGM04_01565	COG0598	Magnesium transport protein CorA
FGM04_01585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FGM04_01590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FGM04_01595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_01610	COG0513	Belongs to the DEAD box helicase family
FGM04_01615	COG0386	Belongs to the glutathione peroxidase family
FGM04_01625	COG1181	Belongs to the D-alanine--D-alanine ligase family
FGM04_01630	COG0383	alpha-mannosidase activity
FGM04_01635	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_01635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_01635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_01640	COG2188	Transcriptional regulator
FGM04_01650	COG0488	(ABC) transporter
FGM04_01755	COG1025	Belongs to the peptidase M16 family
FGM04_01760	COG2062	phosphohistidine phosphatase, SixA
FGM04_01770	COG0697	spore germination
FGM04_01775	COG4166	transmembrane transport
FGM04_01780	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FGM04_01785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FGM04_01795	COG4591	ABC-type transport system involved in lipoprotein release permease component
FGM04_01800	COG1136	(ABC) transporter
FGM04_01805	COG4591	ABC-type transport system involved in lipoprotein release permease component
FGM04_01810	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FGM04_01825	COG0544	peptidyl-prolyl cis-trans isomerase activity
FGM04_01830	COG0740	serine-type endopeptidase activity
FGM04_01835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FGM04_01840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FGM04_01845	COG0776	regulation of translation
FGM04_01850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGM04_01855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGM04_01860	COG1215	transferase activity, transferring glycosyl groups
FGM04_01865	COG0438	transferase activity, transferring glycosyl groups
FGM04_01890	COG1570	exodeoxyribonuclease VII activity
FGM04_01895	COG3038	cytochrome b561
FGM04_01900	COG0517	IMP dehydrogenase activity
FGM04_01900	COG0516	GMP reductase activity
FGM04_01905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGM04_01905	COG0519	Catalyzes the synthesis of GMP from XMP
FGM04_01940	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGM04_01945	COG3162	membrane
FGM04_01960	COG1024	Enoyl-CoA hydratase
FGM04_01965	COG1115	amino acid carrier protein
FGM04_01990	COG0058	SHG alpha-glucan phosphorylase activity
FGM04_01995	COG0471	metal ion transport
FGM04_02000	COG3118	belongs to the thioredoxin family
FGM04_02010	COG1132	(ABC) transporter
FGM04_02015	COG1132	(ABC) transporter
FGM04_02025	COG2501	S4 domain
FGM04_02040	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGM04_02085	COG2009	succinate dehydrogenase
FGM04_02090	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FGM04_02095	COG1053	succinate dehydrogenase
FGM04_02105	COG0567	Dehydrogenase, E1 component
FGM04_02110	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGM04_02115	COG0045	succinate-CoA ligase (ADP-forming) activity
FGM04_02135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_02145	COG3842	ATPase activity
FGM04_02150	COG1840	ABC-type Fe3 transport system, periplasmic component
FGM04_02160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FGM04_02170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_02185	COG4235	cytochrome complex assembly
FGM04_02185	COG3088	subunit of a heme lyase
FGM04_02195	COG1138	Cytochrome C-type biogenesis protein
FGM04_02200	COG3301	Polysulphide reductase, NrfD
FGM04_02205	COG0437	4 iron, 4 sulfur cluster binding
FGM04_02210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FGM04_02220	COG0247	lactate metabolic process
FGM04_02225	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
FGM04_02230	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FGM04_02235	COG3012	SEC-C Motif Domain Protein
FGM04_02240	COG0840	transmembrane signaling receptor activity
FGM04_02245	COG1846	Transcriptional regulator
FGM04_02245	COG1940	carbohydrate kinase activity
FGM04_02255	COG0730	response to heat
FGM04_02260	COG0583	DNA-binding transcription factor activity
FGM04_02275	COG3593	DNA synthesis involved in DNA repair
FGM04_02325	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGM04_02330	COG1011	Hydrolase
FGM04_02345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGM04_02350	COG2832	Protein of unknown function (DUF454)
FGM04_02355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FGM04_02365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FGM04_02370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FGM04_02385	COG1560	Kdo2-lipid A biosynthetic process
FGM04_02390	COG1560	Kdo2-lipid A biosynthetic process
FGM04_02415	COG0417	DNA replication proofreading
FGM04_02430	COG1451	nucleotide metabolic process
FGM04_02445	COG3069	C4-dicarboxylate transmembrane transporter activity
FGM04_02460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_02460	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FGM04_02465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGM04_02470	COG0569	domain protein
FGM04_02470	COG2985	domain, Protein
FGM04_02485	COG0556	nucleotide-excision repair
FGM04_02495	COG0586	Pfam SNARE associated Golgi protein
FGM04_02500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FGM04_02505	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGM04_02520	COG4681	YaeQ
FGM04_02565	COG0534	Mate efflux family protein
FGM04_02580	COG0307	riboflavin synthase, alpha
FGM04_02590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_02595	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FGM04_02600	COG0697	spore germination
FGM04_02605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FGM04_02645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGM04_02655	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FGM04_02660	COG2894	cell division
FGM04_02665	COG0850	regulation of cytokinetic process
FGM04_02670	COG3100	YcgL domain-containing protein
FGM04_02675	COG1760	l-serine dehydratase
FGM04_02685	COG1760	l-serine dehydratase
FGM04_02690	COG3123	guanosine phosphorylase activity
FGM04_02700	COG0205	6-phosphofructokinase activity
FGM04_02710	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FGM04_02715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGM04_02725	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FGM04_02730	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FGM04_02735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGM04_02750	COG0242	peptide deformylase activity
FGM04_02785	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGM04_02790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGM04_02795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGM04_02805	COG0549	Belongs to the carbamate kinase family
FGM04_02820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_02830	COG0697	spore germination
FGM04_02835	COG3385	transposase activity
FGM04_02840	COG0366	Alpha amylase catalytic
FGM04_02855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FGM04_02860	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FGM04_02865	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FGM04_02870	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FGM04_02875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FGM04_02880	COG0072	phenylalanine-tRNA ligase activity
FGM04_02880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_02885	COG0776	regulation of translation
FGM04_02890	COG0784	Response regulator, receiver
FGM04_02890	COG2205	protein histidine kinase activity
FGM04_02905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FGM04_02925	COG2199	diguanylate cyclase activity
FGM04_02930	COG1609	Transcriptional regulator
FGM04_02935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_02940	COG1879	ABC-type sugar transport system periplasmic component
FGM04_02945	COG1172	Belongs to the binding-protein-dependent transport system permease family
FGM04_02950	COG1129	ABC transporter
FGM04_02955	COG1869	D-ribose catabolic process
FGM04_02960	COG0625	glutathione transferase activity
FGM04_02970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGM04_02975	COG1177	transmembrane transport
FGM04_02980	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGM04_03000	COG0037	tRNA processing
FGM04_03005	COG0589	response to stress
FGM04_03010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGM04_03025	COG2217	Heavy metal translocating P-type atpase
FGM04_03035	COG2010	Cytochrome c
FGM04_03050	COG3278	Belongs to the heme-copper respiratory oxidase family
FGM04_03060	COG1956	GAF domain-containing protein
FGM04_03065	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FGM04_03075	COG0308	aminopeptidase N
FGM04_03085	COG2902	Dehydrogenase
FGM04_03090	COG0167	dihydroorotate dehydrogenase activity
FGM04_03105	COG0254	rRNA binding
FGM04_03110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGM04_03115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGM04_03115	COG0116	Belongs to the methyltransferase superfamily
FGM04_03135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGM04_03140	COG1067	ATP-dependent peptidase activity
FGM04_03180	COG4128	Pfam Zonular occludens toxin
FGM04_03260	COG3141	response to X-ray
FGM04_03265	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FGM04_03270	COG4221	oxidoreductase activity
FGM04_03315	COG0372	Belongs to the citrate synthase family
FGM04_03320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FGM04_03330	COG2995	paraquat-inducible protein a
FGM04_03335	COG3008	intermembrane lipid transfer
FGM04_03340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGM04_03340	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FGM04_03355	COG0084	hydrolase, TatD family'
FGM04_03360	COG0470	DNA polymerase III
FGM04_03365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FGM04_03370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FGM04_03375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGM04_03380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FGM04_03385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FGM04_03390	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_03400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FGM04_03405	COG0416	fatty acid biosynthetic process
FGM04_03410	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FGM04_03415	COG1399	metal-binding, possibly nucleic acid-binding protein
FGM04_03420	COG0424	maF-like protein
FGM04_03435	COG1530	ribonuclease E activity
FGM04_03445	COG0306	phosphate transporter
FGM04_03450	COG0717	Belongs to the dCTP deaminase family
FGM04_03455	COG0572	uridine kinase
FGM04_03460	COG0489	protein tyrosine kinase activity
FGM04_03465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_03465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_03475	COG1254	Belongs to the acylphosphatase family
FGM04_03485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FGM04_03500	COG0709	Synthesizes selenophosphate from selenide and ATP
FGM04_03505	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FGM04_03510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGM04_03520	COG0318	PFAM AMP-dependent synthetase and ligase
FGM04_03525	COG2267	carboxylic ester hydrolase activity
FGM04_03535	COG1214	PFAM Peptidase M22, glycoprotease
FGM04_03540	COG1199	ATP-dependent helicase activity
FGM04_03550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FGM04_03555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FGM04_03560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FGM04_03565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGM04_03565	COG0131	Imidazoleglycerol-phosphate dehydratase
FGM04_03570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FGM04_03575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FGM04_03580	COG0107	imidazoleglycerol-phosphate synthase activity
FGM04_03595	COG3706	GGDEF domain
FGM04_03600	COG0318	PFAM AMP-dependent synthetase and ligase
FGM04_03610	COG3134	Outer membrane lipoprotein
FGM04_03615	COG2080	2 iron, 2 sulfur cluster binding
FGM04_03620	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGM04_03625	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGM04_03630	COG2252	PERMEase
FGM04_03635	COG0402	S-adenosylhomocysteine deaminase activity
FGM04_03640	COG2233	PERMEase
FGM04_03645	COG2080	2 iron, 2 sulfur cluster binding
FGM04_03645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FGM04_03650	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FGM04_03655	COG0402	S-adenosylhomocysteine deaminase activity
FGM04_03660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_03660	COG0493	'glutamate synthase
FGM04_03665	COG2068	MobA-Related Protein
FGM04_03670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FGM04_03675	COG3608	succinylglutamate desuccinylase aspartoacylase
FGM04_03675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FGM04_03685	COG3385	transposase activity
FGM04_03695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FGM04_03705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FGM04_03715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_03720	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FGM04_03725	COG3313	Fe-S protein
FGM04_03730	COG2942	2-epimerase
FGM04_03735	COG3716	PTS system mannose fructose sorbose family IID component
FGM04_03740	COG3715	PTS system
FGM04_03745	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_03745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_03760	COG1609	Transcriptional regulator
FGM04_03765	COG2140	Oxalate decarboxylase
FGM04_03770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_03770	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FGM04_03770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_03775	COG1105	Belongs to the carbohydrate kinase PfkB family
FGM04_03780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_03780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_03785	COG1609	Transcriptional regulator
FGM04_03790	COG0814	amino acid
FGM04_03800	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FGM04_03810	COG0513	Belongs to the DEAD box helicase family
FGM04_03820	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FGM04_03825	COG2890	protein-(glutamine-N5) methyltransferase activity
FGM04_03830	COG2840	Smr protein MutS2
FGM04_03835	COG3706	GGDEF domain
FGM04_03840	COG0406	alpha-ribazole phosphatase activity
FGM04_03860	COG2824	Alkylphosphonate utilization operon protein PhnA
FGM04_03880	COG0814	amino acid
FGM04_03885	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FGM04_03890	COG0514	ATP-dependent DNA helicase (RecQ)
FGM04_03895	COG2766	serine protein kinase
FGM04_03900	COG2718	Belongs to the UPF0229 family
FGM04_03905	COG2719	SpoVR family
FGM04_03910	COG1024	Enoyl-CoA hydratase
FGM04_03910	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGM04_03915	COG0183	Belongs to the thiolase family
FGM04_03920	COG0714	Associated with various cellular activities
FGM04_03940	COG2304	oxidoreductase activity
FGM04_03950	COG1595	DNA-templated transcription, initiation
FGM04_03960	COG2067	long-chain fatty acid transport protein
FGM04_03965	COG2067	long-chain fatty acid transport protein
FGM04_03970	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FGM04_03985	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FGM04_03995	COG1643	Atp-dependent helicase
FGM04_04005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_04015	COG2925	Exonuclease
FGM04_04025	COG3345	alpha-galactosidase
FGM04_04030	COG1380	Effector of murein hydrolase LrgA
FGM04_04035	COG1346	cytolysis
FGM04_04040	COG0295	cytidine deaminase activity
FGM04_04050	COG3033	Beta-eliminating lyase
FGM04_04060	COG3046	protein related to deoxyribodipyrimidine photolyase
FGM04_04065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_04070	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FGM04_04095	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_04115	COG3158	transport of potassium into the cell
FGM04_04120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_04125	COG0651	ATP synthesis coupled electron transport
FGM04_04130	COG0650	Formate hydrogenlyase subunit 4
FGM04_04135	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FGM04_04135	COG3261	NADH dehydrogenase
FGM04_04140	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_04145	COG3260	NADH ubiquinone oxidoreductase 20
FGM04_04155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FGM04_04160	COG1921	L-seryl-tRNASec selenium transferase activity
FGM04_04170	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FGM04_04175	COG0298	carbon dioxide binding
FGM04_04185	COG0309	Hydrogenase expression formation protein (HypE)
FGM04_04190	COG0375	protein maturation
FGM04_04195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FGM04_04200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGM04_04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGM04_04215	COG0601	transmembrane transport
FGM04_04225	COG1773	rubredoxin
FGM04_04230	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FGM04_04235	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FGM04_04240	COG5557	Pfam Polysulphide reductase, NrfD
FGM04_04245	COG0437	4 iron, 4 sulfur cluster binding
FGM04_04250	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FGM04_04255	COG4251	negative regulation of phosphorylation
FGM04_04255	COG3706	GGDEF domain
FGM04_04255	COG5001	Diguanylate cyclase
FGM04_04255	COG2203	Gaf domain
FGM04_04260	COG0438	transferase activity, transferring glycosyl groups
FGM04_04265	COG0438	transferase activity, transferring glycosyl groups
FGM04_04285	COG0438	transferase activity, transferring glycosyl groups
FGM04_04365	COG0784	Response regulator, receiver
FGM04_04365	COG2205	protein histidine kinase activity
FGM04_04430	COG2003	Belongs to the UPF0758 family
FGM04_04460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGM04_04480	COG0730	response to heat
FGM04_04490	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_04500	COG1024	Enoyl-CoA hydratase
FGM04_04505	COG1024	Enoyl-CoA hydratase
FGM04_04510	COG1960	acyl-CoA dehydrogenase activity
FGM04_04515	COG1960	acyl-CoA dehydrogenase activity
FGM04_04520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FGM04_04525	COG1024	Enoyl-CoA hydratase
FGM04_04555	COG1584	GPR1 FUN34 yaaH family protein
FGM04_04580	COG2983	Belongs to the UPF0260 family
FGM04_04585	COG1882	Formate acetyltransferase
FGM04_04590	COG2116	formate transmembrane transporter activity
FGM04_04595	COG1944	ATP diphosphatase activity
FGM04_04600	COG2723	6-phospho-beta-galactosidase activity
FGM04_04605	COG0583	DNA-binding transcription factor activity
FGM04_04615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FGM04_04620	COG0583	DNA-binding transcription factor activity
FGM04_04630	COG1335	isochorismatase
FGM04_04640	COG2271	Major facilitator Superfamily
FGM04_04645	COG0583	DNA-binding transcription factor activity
FGM04_04650	COG0583	DNA-binding transcription factor activity
FGM04_04655	COG2910	NAD(P)H-binding
FGM04_04690	COG0861	Integral membrane protein TerC family
FGM04_04695	COG2885	chlorophyll binding
FGM04_04700	COG2199	diguanylate cyclase activity
FGM04_04720	COG2154	pterin-4-alpha-carbinolamine dehydratase
FGM04_04730	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_04735	COG1177	transmembrane transport
FGM04_04740	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGM04_04745	COG3842	ATPase activity
FGM04_04750	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FGM04_04755	COG0583	DNA-binding transcription factor activity
FGM04_04760	COG3768	UPF0283 membrane protein
FGM04_04765	COG3106	COG3106 Predicted ATPase
FGM04_04780	COG1842	Phage shock protein A
FGM04_04785	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FGM04_04795	COG4168	peptide transport system, permease
FGM04_04800	COG4171	peptide transport system, permease
FGM04_04805	COG4172	Belongs to the ABC transporter superfamily
FGM04_04810	COG4172	Belongs to the ABC transporter superfamily
FGM04_04815	COG0326	Molecular chaperone. Has ATPase activity
FGM04_04820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FGM04_04845	COG3039	Transposase
FGM04_04920	COG1435	thymidine kinase activity
FGM04_04925	COG1757	Na H antiporter
FGM04_04930	COG2916	Histone family protein nucleoid-structuring protein H-NS
FGM04_04935	COG2096	Adenosyltransferase
FGM04_04940	COG3530	Putative quorum-sensing-regulated virulence factor
FGM04_04945	COG0602	queuosine metabolic process
FGM04_04950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FGM04_04970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FGM04_04980	COG0776	regulation of translation
FGM04_04985	COG0539	negative regulation of cytoplasmic translation
FGM04_04990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FGM04_04995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGM04_05010	COG2814	Major facilitator Superfamily
FGM04_05025	COG0778	Nitroreductase
FGM04_05030	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FGM04_05035	COG3300	MHYT domain
FGM04_05035	COG5001	Diguanylate cyclase
FGM04_05040	COG0583	DNA-binding transcription factor activity
FGM04_05045	COG3437	response regulator, receiver
FGM04_05070	COG4989	oxidoreductase activity
FGM04_05075	COG0724	RNA recognition motif
FGM04_05085	COG1126	abc transporter atp-binding protein
FGM04_05090	COG0765	amino acid transport
FGM04_05095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_05100	COG4597	amino acid ABC transporter
FGM04_05105	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FGM04_05115	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FGM04_05130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGM04_05135	COG1360	Flagellar Motor Protein
FGM04_05140	COG4771	TonB-dependent receptor
FGM04_05145	COG1770	oligopeptidase
FGM04_05170	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_05175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_05180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_05180	COG0649	NAD binding
FGM04_05195	COG1034	ATP synthesis coupled electron transport
FGM04_05200	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FGM04_05205	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_05210	COG0839	Belongs to the complex I subunit 6 family
FGM04_05215	COG0713	ATP synthesis coupled electron transport
FGM04_05225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_05230	COG1007	ATP synthesis coupled electron transport
FGM04_05245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_05245	COG2199	diguanylate cyclase activity
FGM04_05250	COG0047	phosphoribosylformylglycinamidine synthase activity
FGM04_05250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FGM04_05255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGM04_05265	COG1645	bacterial-type flagellum-dependent swarming motility
FGM04_05270	COG1160	GTP binding
FGM04_05275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_05280	COG2976	Protein conserved in bacteria
FGM04_05285	COG0124	histidyl-tRNA synthetase
FGM04_05305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FGM04_05310	COG0105	UTP biosynthetic process
FGM04_05325	COG0633	Ferredoxin
FGM04_05330	COG0443	Heat shock 70 kDa protein
FGM04_05335	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FGM04_05345	COG0822	iron-sulfur transferase activity
FGM04_05350	COG1104	cysteine desulfurase activity
FGM04_05395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_05400	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_05405	COG1862	Preprotein translocase
FGM04_05410	COG0343	queuine tRNA-ribosyltransferase activity
FGM04_05415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FGM04_05420	COG0517	IMP dehydrogenase activity
FGM04_05425	COG0450	alkyl hydroperoxide reductase
FGM04_05430	COG3634	alkyl hydroperoxide reductase activity
FGM04_05470	COG0574	Belongs to the PEP-utilizing enzyme family
FGM04_05470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FGM04_05475	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FGM04_05505	COG0840	transmembrane signaling receptor activity
FGM04_05510	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGM04_05510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FGM04_05515	COG0509	glycine decarboxylation via glycine cleavage system
FGM04_05520	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FGM04_05530	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGM04_05535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGM04_05545	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FGM04_05555	COG2814	Major facilitator Superfamily
FGM04_05560	COG0625	glutathione transferase activity
FGM04_05570	COG0483	inositol monophosphate 1-phosphatase activity
FGM04_05585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FGM04_05625	COG1334	flagellar protein FlaG
FGM04_05670	COG0656	L-ascorbic acid biosynthetic process
FGM04_05680	COG2814	Major facilitator Superfamily
FGM04_05700	COG3220	belongs to the UPF0276 family
FGM04_05720	COG1294	oxidase, subunit
FGM04_05730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGM04_05740	COG2979	Protein of unknown function (DUF533)
FGM04_05745	COG1607	acyl-coa hydrolase
FGM04_05755	COG0583	DNA-binding transcription factor activity
FGM04_05760	COG2807	transmembrane transport
FGM04_05765	COG1187	pseudouridine synthase activity
FGM04_05780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGM04_05780	COG0301	tRNA thio-modification
FGM04_05795	COG4953	penicillin-binding protein 1C
FGM04_05800	COG2373	Large extracellular alpha-helical protein
FGM04_05810	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_05820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_05830	COG1252	NADH dehydrogenase
FGM04_05840	COG2233	PERMEase
FGM04_05850	COG2354	Protein conserved in bacteria
FGM04_05860	COG0840	transmembrane signaling receptor activity
FGM04_05865	COG1301	dicarboxylic acid transport
FGM04_05880	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FGM04_05895	COG0537	adenosine 5'-monophosphoramidase activity
FGM04_05930	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_05935	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FGM04_05945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_05950	COG0287	Prephenate dehydrogenase
FGM04_05950	COG1605	Chorismate mutase
FGM04_05960	COG1199	ATP-dependent helicase activity
FGM04_05970	COG0123	including yeast histone deacetylase and acetoin utilization protein
FGM04_05975	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FGM04_05980	COG1785	Belongs to the alkaline phosphatase family
FGM04_06000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGM04_06005	COG2197	response regulator
FGM04_06015	COG2271	Major facilitator Superfamily
FGM04_06020	COG3706	GGDEF domain
FGM04_06025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_06030	COG0765	amino acid transport
FGM04_06035	COG1126	abc transporter atp-binding protein
FGM04_06050	COG0531	amino acid
FGM04_06065	COG1253	flavin adenine dinucleotide binding
FGM04_06070	COG0704	Plays a role in the regulation of phosphate uptake
FGM04_06080	COG0581	inorganic phosphate transmembrane transporter activity
FGM04_06085	COG0573	inorganic phosphate transmembrane transporter activity
FGM04_06090	COG0590	tRNA wobble adenosine to inosine editing
FGM04_06100	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FGM04_06120	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FGM04_06125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FGM04_06130	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FGM04_06135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FGM04_06140	COG2204	response regulator
FGM04_06145	COG3852	Histidine kinase
FGM04_06150	COG2204	response regulator
FGM04_06160	COG2716	regulation of RNA biosynthetic process
FGM04_06165	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FGM04_06170	COG0248	Ppx GppA phosphatase
FGM04_06175	COG2239	Acts as a magnesium transporter
FGM04_06180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FGM04_06190	COG1705	Flagellar rod assembly protein muramidase FlgJ
FGM04_06190	COG3951	Flagellar rod assembly protein muramidase FlgJ
FGM04_06195	COG1706	bacterial-type flagellum-dependent cell motility
FGM04_06200	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FGM04_06205	COG4786	Flagellar basal body rod
FGM04_06210	COG4787	bacterial-type flagellum-dependent cell motility
FGM04_06220	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FGM04_06225	COG1558	bacterial-type flagellum-dependent cell motility
FGM04_06230	COG1815	bacterial-type flagellum-dependent cell motility
FGM04_06235	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FGM04_06240	COG0835	chemotaxis
FGM04_06240	COG0784	Response regulator, receiver
FGM04_06245	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FGM04_06260	COG0622	Phosphoesterase
FGM04_06265	COG4166	transmembrane transport
FGM04_06275	COG1187	pseudouridine synthase activity
FGM04_06280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_06290	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGM04_06295	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_06305	COG1349	DNA-binding transcription factor activity
FGM04_06310	COG4166	transmembrane transport
FGM04_06335	COG1278	Cold shock
FGM04_06360	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FGM04_06360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FGM04_06365	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_06370	COG3433	isochorismatase activity
FGM04_06370	COG1535	isochorismatase
FGM04_06375	COG1021	2,3-dihydroxybenzoate-AMP ligase
FGM04_06380	COG1169	isochorismate synthase
FGM04_06385	COG4771	TonB-dependent receptor
FGM04_06390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FGM04_06400	COG0741	lytic transglycosylase activity
FGM04_06410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FGM04_06430	COG2911	Protein conserved in bacteria
FGM04_06435	COG0729	surface antigen
FGM04_06445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGM04_06455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FGM04_06465	COG4134	Bacterial extracellular solute-binding protein
FGM04_06475	COG4136	ATPase activity
FGM04_06480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FGM04_06485	COG2951	lytic endotransglycosylase activity
FGM04_06490	COG0033	Phosphoglucomutase
FGM04_06495	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FGM04_06500	COG0596	Alpha beta hydrolase
FGM04_06515	COG0716	FMN binding
FGM04_06525	COG0735	belongs to the Fur family
FGM04_06530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGM04_06540	COG1263	PTS System
FGM04_06540	COG2190	(PTS) system
FGM04_06540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_06545	COG0363	glucosamine-6-phosphate deaminase activity
FGM04_06550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FGM04_06555	COG1940	carbohydrate kinase activity
FGM04_06555	COG1846	Transcriptional regulator
FGM04_06565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_06565	COG2199	diguanylate cyclase activity
FGM04_06570	COG3275	phosphorelay sensor kinase activity
FGM04_06575	COG3279	Response regulator of the LytR AlgR family
FGM04_06580	COG1966	Carbon starvation protein
FGM04_06590	COG1566	PFAM secretion protein HlyD family protein
FGM04_06595	COG1061	Type III restriction enzyme res subunit
FGM04_06600	COG2027	D-alanyl-D-alanine carboxypeptidase
FGM04_06605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FGM04_06610	COG3021	interspecies interaction between organisms
FGM04_06620	COG1607	acyl-coa hydrolase
FGM04_06625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGM04_06645	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGM04_06645	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGM04_06645	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGM04_06645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FGM04_06660	COG3217	Mosc domain protein beta barrel domain protein
FGM04_06660	COG0633	Ferredoxin
FGM04_06660	COG3217	Mosc domain protein beta barrel domain protein
FGM04_06660	COG0633	Ferredoxin
FGM04_06665	COG0471	metal ion transport
FGM04_06675	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FGM04_06680	COG0791	NLP P60 protein
FGM04_06690	COG3118	belongs to the thioredoxin family
FGM04_06700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FGM04_06705	COG0788	formyltetrahydrofolate deformylase activity
FGM04_06715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGM04_06730	COG0741	lytic transglycosylase activity
FGM04_06730	COG1196	nuclear chromosome segregation
FGM04_06730	COG0739	heme binding
FGM04_06735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FGM04_06745	COG0436	Aminotransferase
FGM04_06770	COG0564	pseudouridine synthase activity
FGM04_06780	COG1454	alcohol dehydrogenase
FGM04_06785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_06790	COG0702	epimerase
FGM04_06800	COG0095	Lipoate-protein ligase
FGM04_06810	COG0577	efflux transmembrane transporter activity
FGM04_06810	COG1136	(ABC) transporter
FGM04_06815	COG0577	efflux transmembrane transporter activity
FGM04_06815	COG1136	(ABC) transporter
FGM04_06820	COG0577	efflux transmembrane transporter activity
FGM04_06820	COG1136	(ABC) transporter
FGM04_06840	COG2391	methyltransferase activity
FGM04_06860	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_06870	COG1285	pathogenesis
FGM04_06900	COG0484	heat shock protein binding
FGM04_06905	COG0443	Heat shock 70 kDa protein
FGM04_06910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FGM04_06915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FGM04_06920	COG0497	DNA recombination
FGM04_06925	COG1227	inorganic diphosphatase activity
FGM04_06930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_06935	COG1136	(ABC) transporter
FGM04_06935	COG0577	efflux transmembrane transporter activity
FGM04_06940	COG1538	Outer membrane efflux protein
FGM04_06955	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_06990	COG1091	dTDP-4-dehydrorhamnose reductase activity
FGM04_07015	COG0438	transferase activity, transferring glycosyl groups
FGM04_07040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FGM04_07050	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FGM04_07060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FGM04_07070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_07075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_07080	COG1309	transcriptional regulator
FGM04_07095	COG1342	Belongs to the UPF0251 family
FGM04_07115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGM04_07130	COG1943	Transposase
FGM04_07145	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FGM04_07150	COG0083	homoserine kinase activity
FGM04_07165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FGM04_07170	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FGM04_07175	COG1946	Acyl-CoA thioesterase
FGM04_07185	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FGM04_07195	COG0009	L-threonylcarbamoyladenylate synthase
FGM04_07205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FGM04_07210	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGM04_07210	COG0512	Glutamine amidotransferase of anthranilate synthase
FGM04_07215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FGM04_07220	COG0135	phosphoribosylanthranilate isomerase activity
FGM04_07220	COG0134	indole-3-glycerol-phosphate synthase activity
FGM04_07225	COG0133	tryptophan synthase activity
FGM04_07230	COG0159	tryptophan synthase activity
FGM04_07235	COG1196	nuclear chromosome segregation
FGM04_07240	COG1988	membrane-bound metal-dependent
FGM04_07260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_07270	COG0798	PFAM Bile acid sodium symporter
FGM04_07300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGM04_07310	COG0745	RESPONSE REGULATOR receiver
FGM04_07330	COG4988	ABC transporter
FGM04_07335	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FGM04_07355	COG1720	tRNA m6t6A37 methyltransferase activity
FGM04_07360	COG3038	cytochrome b561
FGM04_07370	COG0745	RESPONSE REGULATOR receiver
FGM04_07380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGM04_07380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGM04_07390	COG1882	Formate acetyltransferase
FGM04_07395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGM04_07405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FGM04_07410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FGM04_07420	COG2853	Lipoprotein
FGM04_07430	COG4235	cytochrome complex assembly
FGM04_07430	COG3088	subunit of a heme lyase
FGM04_07435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGM04_07440	COG1138	Cytochrome C-type biogenesis protein
FGM04_07445	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FGM04_07450	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGM04_07455	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGM04_07460	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FGM04_07475	COG0835	chemotaxis
FGM04_07485	COG1192	Involved in chromosome partitioning
FGM04_07495	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGM04_07505	COG0643	Histidine kinase
FGM04_07505	COG2198	Histidine kinase
FGM04_07510	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FGM04_07525	COG0455	bacterial-type flagellum organization
FGM04_07535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FGM04_07545	COG1684	flagellar biosynthetic protein fliR
FGM04_07550	COG1987	bacterial-type flagellum assembly
FGM04_07600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FGM04_07610	COG1677	Flagellar hook-basal body complex protein FliE
FGM04_07630	COG0469	pyruvate kinase activity
FGM04_07635	COG1737	Transcriptional regulator
FGM04_07640	COG0837	glucose binding
FGM04_07670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_07685	COG0281	malic enzyme
FGM04_07695	COG0534	Mate efflux family protein
FGM04_07705	COG3706	GGDEF domain
FGM04_07710	COG2233	PERMEase
FGM04_07715	COG0095	Lipoate-protein ligase
FGM04_07720	COG1115	amino acid carrier protein
FGM04_07725	COG0019	diaminopimelate decarboxylase activity
FGM04_07735	COG0678	peroxiredoxin activity
FGM04_07760	COG0545	Peptidyl-prolyl cis-trans isomerase
FGM04_07765	COG3142	Participates in the control of copper homeostasis
FGM04_07780	COG4783	chaperone-mediated protein folding
FGM04_07790	COG5002	protein histidine kinase activity
FGM04_07795	COG0745	RESPONSE REGULATOR receiver
FGM04_07800	COG0346	lactoylglutathione lyase activity
FGM04_07805	COG3284	Transcriptional regulator
FGM04_07810	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_07820	COG0697	spore germination
FGM04_07830	COG3290	protein histidine kinase activity
FGM04_07835	COG0281	malic enzyme
FGM04_07845	COG1846	Transcriptional regulator
FGM04_07850	COG1566	PFAM secretion protein HlyD family protein
FGM04_07880	COG0602	queuosine metabolic process
FGM04_07885	COG1328	CTP reductase activity
FGM04_07895	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FGM04_07900	COG3115	cell septum assembly
FGM04_07905	COG1196	nuclear chromosome segregation
FGM04_07915	COG2860	membrane
FGM04_07925	COG3108	Peptidase M15
FGM04_07930	COG2989	Protein conserved in bacteria
FGM04_07945	COG0463	Glycosyl transferase, family 2
FGM04_07960	COG0366	Alpha amylase catalytic
FGM04_07995	COG2203	Gaf domain
FGM04_07995	COG2199	diguanylate cyclase activity
FGM04_08005	COG3590	peptidase
FGM04_08015	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FGM04_08020	COG1982	Orn Lys Arg decarboxylase major
FGM04_08025	COG0531	amino acid
FGM04_08030	COG3710	Transcriptional regulator
FGM04_08035	COG0531	amino acid
FGM04_08055	COG0814	amino acid
FGM04_08085	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGM04_08090	COG0739	heme binding
FGM04_08095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FGM04_08105	COG0251	oxidation-reduction process
FGM04_08120	COG0583	DNA-binding transcription factor activity
FGM04_08140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FGM04_08150	COG3091	SprT-like family
FGM04_08160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FGM04_08165	COG0189	ligase activity
FGM04_08170	COG1678	Uncharacterized ACR, COG1678
FGM04_08175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FGM04_08180	COG3104	oligopeptide transport
FGM04_08185	COG0583	DNA-binding transcription factor activity
FGM04_08195	COG0714	Associated with various cellular activities
FGM04_08210	COG1115	amino acid carrier protein
FGM04_08215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FGM04_08225	COG0825	malonyl-CoA metabolic process
FGM04_08235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FGM04_08240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_08245	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_08250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FGM04_08255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FGM04_08270	COG0750	zinc metalloprotease
FGM04_08275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FGM04_08280	COG0575	Belongs to the CDS family
FGM04_08290	COG0233	cytoplasmic translational termination
FGM04_08295	COG0528	UMP kinase activity
FGM04_08300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FGM04_08305	COG0052	Belongs to the universal ribosomal protein uS2 family
FGM04_08310	COG0024	Methionine aminopeptidase
FGM04_08320	COG2171	N-acyltransferase activity
FGM04_08330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_08330	COG1263	PTS System
FGM04_08350	COG0564	pseudouridine synthase activity
FGM04_08355	COG3098	single-species biofilm formation
FGM04_08380	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FGM04_08390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FGM04_08390	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FGM04_08400	COG3706	GGDEF domain
FGM04_08405	COG1611	Belongs to the LOG family
FGM04_08410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGM04_08415	COG0473	3-isopropylmalate dehydrogenase activity
FGM04_08425	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FGM04_08430	COG2363	Small membrane protein
FGM04_08440	COG0583	DNA-binding transcription factor activity
FGM04_08445	COG0840	transmembrane signaling receptor activity
FGM04_08450	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGM04_08465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FGM04_08470	COG1666	GTP binding
FGM04_08480	COG2211	Major facilitator Superfamily
FGM04_08485	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FGM04_08495	COG2813	Specifically methylates the guanine in position
FGM04_08500	COG0271	Belongs to the BolA IbaG family
FGM04_08505	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_08510	COG1805	sodium ion transport
FGM04_08520	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_08525	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FGM04_08530	COG2871	sodium ion transport
FGM04_08535	COG1477	protein flavinylation
FGM04_08565	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FGM04_08580	COG0300	oxidoreductase activity
FGM04_08590	COG0415	Belongs to the DNA photolyase family
FGM04_08595	COG0789	Transcriptional regulator
FGM04_08600	COG3272	Protein of unknown function (DUF1722)
FGM04_08630	COG0077	Prephenate dehydratase
FGM04_08630	COG1605	Chorismate mutase
FGM04_08670	COG0300	oxidoreductase activity
FGM04_08695	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FGM04_08735	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FGM04_08740	COG0826	peptidase U32
FGM04_08745	COG1280	lysine exporter protein (LysE YggA)
FGM04_08775	COG0643	Histidine kinase
FGM04_08775	COG2198	Histidine kinase
FGM04_08785	COG0835	chemotaxis
FGM04_08790	COG0840	transmembrane signaling receptor activity
FGM04_08800	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FGM04_08805	COG2201	protein-glutamate methylesterase activity
FGM04_08810	COG1185	polyribonucleotide nucleotidyltransferase activity
FGM04_08815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FGM04_08820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FGM04_08825	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FGM04_08830	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FGM04_08835	COG0195	Participates in both transcription termination and antitermination
FGM04_08840	COG0779	Required for maturation of 30S ribosomal subunits
FGM04_08855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGM04_08860	COG0149	triose-phosphate isomerase activity
FGM04_08865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FGM04_08870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FGM04_08875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGM04_08880	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FGM04_08885	COG1534	Rna-binding protein
FGM04_08895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGM04_08900	COG1360	Flagellar Motor Protein
FGM04_08905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FGM04_08910	COG1722	exodeoxyribonuclease VII activity
FGM04_08915	COG0142	geranyltranstransferase activity
FGM04_08920	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FGM04_08935	COG4145	pantothenate transmembrane transporter activity
FGM04_08940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_08940	COG2190	(PTS) system
FGM04_08940	COG1263	PTS System
FGM04_08945	COG0583	DNA-binding transcription factor activity
FGM04_08950	COG0604	alcohol dehydrogenase
FGM04_08955	COG2264	protein methyltransferase activity
FGM04_08960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FGM04_08965	COG0110	maltose O-acetyltransferase activity
FGM04_08970	COG0778	Nitroreductase
FGM04_08975	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_08975	COG1902	pentaerythritol trinitrate reductase activity
FGM04_08980	COG0616	signal peptide processing
FGM04_09005	COG0748	coenzyme F420 binding
FGM04_09010	COG3721	Heme iron utilization protein
FGM04_09020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_09035	COG3275	phosphorelay sensor kinase activity
FGM04_09040	COG3279	Response regulator of the LytR AlgR family
FGM04_09045	COG1966	Carbon starvation protein
FGM04_09050	COG3340	Belongs to the peptidase S51 family
FGM04_09055	COG0432	Pfam Uncharacterised protein family UPF0047
FGM04_09060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FGM04_09065	COG0305	Participates in initiation and elongation during chromosome replication
FGM04_09075	COG0737	Belongs to the 5'-nucleotidase family
FGM04_09095	COG2204	response regulator
FGM04_09100	COG0545	Peptidyl-prolyl cis-trans isomerase
FGM04_09110	COG2900	Belongs to the SlyX family
FGM04_09125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_09130	COG2313	pseudouridylate synthase activity
FGM04_09155	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FGM04_09250	COG2985	domain, Protein
FGM04_09250	COG0569	domain protein
FGM04_09255	COG1272	protein, Hemolysin III
FGM04_09260	COG0076	glutamate decarboxylase activity
FGM04_09265	COG2917	probably involved in intracellular septation
FGM04_09270	COG2350	Protein conserved in bacteria
FGM04_09280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FGM04_09285	COG1381	Involved in DNA repair and RecF pathway recombination
FGM04_09300	COG0681	Belongs to the peptidase S26 family
FGM04_09305	COG0481	GTPase activity
FGM04_09315	COG3026	antisigma factor binding
FGM04_09320	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FGM04_09325	COG1595	DNA-templated transcription, initiation
FGM04_09330	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FGM04_09340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FGM04_09345	COG0354	folic acid binding
FGM04_09390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_09395	COG0191	fructose-bisphosphate aldolase activity
FGM04_09400	COG0126	phosphoglycerate kinase activity
FGM04_09405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGM04_09410	COG1940	carbohydrate kinase activity
FGM04_09415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FGM04_09420	COG2816	NAD+ diphosphatase activity
FGM04_09430	COG4991	sh3 domain protein
FGM04_09435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGM04_09445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGM04_09450	COG0840	transmembrane signaling receptor activity
FGM04_09460	COG1278	Cold shock
FGM04_09500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FGM04_09505	COG1162	GTPase activity
FGM04_09510	COG0688	phosphatidylethanolamine metabolic process
FGM04_09515	COG4628	conserved protein (DUF2132)
FGM04_09530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FGM04_09550	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FGM04_09560	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGM04_09565	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FGM04_09570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FGM04_09575	COG3178	'Phosphotransferase
FGM04_09580	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FGM04_09585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FGM04_09590	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FGM04_09595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FGM04_09605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FGM04_09620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FGM04_09635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FGM04_09640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FGM04_09645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FGM04_09650	COG0142	geranyltranstransferase activity
FGM04_09655	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FGM04_09660	COG0330	HflC and HflK could
FGM04_09665	COG0330	HflC and HflK could
FGM04_09670	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FGM04_09675	COG1923	regulation of RNA biosynthetic process
FGM04_09680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FGM04_09685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGM04_09690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FGM04_09700	COG0802	atpase or kinase
FGM04_09705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FGM04_09705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FGM04_09725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FGM04_09730	COG2011	ABC-type metal ion transport system permease component
FGM04_09735	COG1464	Belongs to the NlpA lipoprotein family
FGM04_09770	COG0784	Response regulator, receiver
FGM04_09770	COG5002	protein histidine kinase activity
FGM04_09770	COG2198	Histidine kinase
FGM04_09805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FGM04_09810	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FGM04_09815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGM04_09820	COG2716	regulation of RNA biosynthetic process
FGM04_09825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FGM04_09830	COG3013	Belongs to the UPF0304 family
FGM04_09835	COG3092	negative regulation of chromosome organization
FGM04_09840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FGM04_09845	COG0280	phosphate acetyltransferase
FGM04_09845	COG0857	belongs to the CobB CobQ family
FGM04_09850	COG1555	photosystem II stabilization
FGM04_09855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FGM04_09860	COG3104	oligopeptide transport
FGM04_09865	COG0745	RESPONSE REGULATOR receiver
FGM04_09895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_09910	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FGM04_09945	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGM04_09955	COG1401	restriction endodeoxyribonuclease activity
FGM04_09960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGM04_09970	COG0732	type I restriction modification DNA specificity domain
FGM04_09975	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FGM04_09980	COG1715	Restriction endonuclease
FGM04_10025	COG2003	Belongs to the UPF0758 family
FGM04_10070	COG3311	Transcriptional regulator
FGM04_10115	COG0440	acetolactate synthase activity
FGM04_10120	COG0028	Belongs to the TPP enzyme family
FGM04_10145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FGM04_10150	COG0473	3-isopropylmalate dehydrogenase activity
FGM04_10155	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FGM04_10160	COG0066	3-isopropylmalate dehydratase activity
FGM04_10175	COG4143	(ABC) transporter
FGM04_10185	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FGM04_10190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FGM04_10240	COG0459	protein refolding
FGM04_10245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FGM04_10255	COG3030	protein affecting phage T7 exclusion by the F plasmid
FGM04_10260	COG1027	Aspartate ammonia-lyase
FGM04_10265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FGM04_10270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FGM04_10275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FGM04_10280	COG1610	YqeY-like protein
FGM04_10285	COG0358	DNA primase activity
FGM04_10290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FGM04_10310	COG0151	Belongs to the GarS family
FGM04_10315	COG0138	bifunctional purine biosynthesis protein purh
FGM04_10325	COG3036	rescue of stalled ribosome
FGM04_10330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGM04_10335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FGM04_10345	COG0673	inositol 2-dehydrogenase activity
FGM04_10355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGM04_10360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGM04_10370	COG0583	DNA-binding transcription factor activity
FGM04_10375	COG0477	Major facilitator Superfamily
FGM04_10390	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_10395	COG0745	RESPONSE REGULATOR receiver
FGM04_10395	COG3706	GGDEF domain
FGM04_10400	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FGM04_10425	COG1022	Amp-dependent synthetase and ligase
FGM04_10430	COG2918	glutathione biosynthetic process
FGM04_10435	COG0612	Peptidase, M16
FGM04_10440	COG1238	metal cluster binding
FGM04_10445	COG1064	alcohol dehydrogenase
FGM04_10470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_10475	COG0359	binds to the 23S rRNA
FGM04_10480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FGM04_10485	COG0360	Binds together with S18 to 16S ribosomal RNA
FGM04_10490	COG1914	H( )-stimulated, divalent metal cation uptake system
FGM04_10495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGM04_10505	COG0776	regulation of translation
FGM04_10520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FGM04_10535	COG0560	Phosphoserine phosphatase
FGM04_10545	COG0813	purine-nucleoside phosphorylase activity
FGM04_10550	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FGM04_10555	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FGM04_10560	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FGM04_10570	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_10575	COG0084	hydrolase, TatD family'
FGM04_10580	COG4968	Prepilin-type N-terminal cleavage methylation domain
FGM04_10590	COG1854	S-ribosylhomocysteine lyase activity
FGM04_10605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FGM04_10605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGM04_10645	COG4968	Prepilin-type N-terminal cleavage methylation domain
FGM04_10650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FGM04_10655	COG1047	Peptidyl-prolyl cis-trans
FGM04_10660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FGM04_10665	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FGM04_10670	COG0196	riboflavin kinase activity
FGM04_10675	COG0728	peptidoglycan biosynthetic process
FGM04_10680	COG0268	Binds directly to 16S ribosomal RNA
FGM04_10685	COG0640	Transcriptional regulator
FGM04_10690	COG0583	DNA-binding transcription factor activity
FGM04_10700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGM04_10725	COG0347	Belongs to the P(II) protein family
FGM04_10745	COG3022	response to hydroperoxide
FGM04_10760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FGM04_10765	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FGM04_10770	COG0762	integral membrane protein
FGM04_10775	COG1872	DUF167
FGM04_10785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_10790	COG0583	DNA-binding transcription factor activity
FGM04_10805	COG1929	Belongs to the glycerate kinase type-1 family
FGM04_10810	COG2610	gluconate transmembrane transporter activity
FGM04_10815	COG3835	regulator
FGM04_10820	COG3112	Uncharacterised protein family (UPF0231)
FGM04_10840	COG3568	Endonuclease Exonuclease Phosphatase
FGM04_10850	COG0513	Belongs to the DEAD box helicase family
FGM04_10875	COG0617	tRNA 3'-terminal CCA addition
FGM04_10880	COG1194	a g-specific adenine glycosylase
FGM04_10885	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FGM04_10895	COG3111	PFAM Bacterial OB fold (BOF) protein
FGM04_10900	COG3240	lipase activity
FGM04_10910	COG3706	GGDEF domain
FGM04_10915	COG0557	exoribonuclease II activity
FGM04_10920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGM04_10930	COG2153	protein acetylation
FGM04_10935	COG0513	Belongs to the DEAD box helicase family
FGM04_10940	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FGM04_10965	COG0735	belongs to the Fur family
FGM04_10970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FGM04_10975	COG0840	transmembrane signaling receptor activity
FGM04_10985	COG4166	transmembrane transport
FGM04_10995	COG0110	maltose O-acetyltransferase activity
FGM04_11005	COG1024	Enoyl-CoA hydratase
FGM04_11020	COG4221	oxidoreductase activity
FGM04_11025	COG0442	prolyl-tRNA aminoacylation
FGM04_11030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGM04_11035	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FGM04_11040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FGM04_11050	COG1051	belongs to the nudix hydrolase family
FGM04_11055	COG3066	DNA modification
FGM04_11065	COG0335	large ribosomal subunit rRNA binding
FGM04_11070	COG0336	Belongs to the RNA methyltransferase TrmD family
FGM04_11075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FGM04_11080	COG0228	four-way junction DNA binding
FGM04_11085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FGM04_11090	COG4137	Cytochrome C assembly protein
FGM04_11095	COG4536	flavin adenine dinucleotide binding
FGM04_11105	COG1017	nitric oxide dioxygenase activity
FGM04_11105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_11110	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FGM04_11115	COG0039	L-malate dehydrogenase activity
FGM04_11120	COG4160	amino acid transport
FGM04_11125	COG4215	(ABC) transporter
FGM04_11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_11135	COG1126	abc transporter atp-binding protein
FGM04_11140	COG1438	arginine binding
FGM04_11145	COG2837	iron assimilation
FGM04_11150	COG3842	ATPase activity
FGM04_11160	COG1840	ABC-type Fe3 transport system, periplasmic component
FGM04_11175	COG1448	Aminotransferase
FGM04_11190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FGM04_11195	COG1328	CTP reductase activity
FGM04_11220	COG0543	2 iron, 2 sulfur cluster binding
FGM04_11220	COG0633	Ferredoxin
FGM04_11235	COG0840	transmembrane signaling receptor activity
FGM04_11240	COG3397	chitin binding
FGM04_11245	COG0583	DNA-binding transcription factor activity
FGM04_11250	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FGM04_11255	COG4208	sulfate ABC transporter
FGM04_11260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FGM04_11270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FGM04_11275	COG3174	membrane
FGM04_11280	COG0110	maltose O-acetyltransferase activity
FGM04_11295	COG1011	Hydrolase
FGM04_11300	COG0494	nUDIX hydrolase
FGM04_11305	COG1218	3'(2'),5'-bisphosphate nucleotidase
FGM04_11310	COG0814	amino acid
FGM04_11315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_11330	COG0626	cystathionine gamma-synthase activity
FGM04_11335	COG0460	homoserine dehydrogenase
FGM04_11335	COG0527	aspartate kinase activity
FGM04_11340	COG0306	phosphate transporter
FGM04_11345	COG1392	Phosphate transport regulator
FGM04_11355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FGM04_11360	COG2813	Specifically methylates the guanine in position
FGM04_11365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FGM04_11370	COG0297	glycogen (starch) synthase activity
FGM04_11410	COG1757	Na H antiporter
FGM04_11415	COG0316	Belongs to the HesB IscA family
FGM04_11425	COG0038	chloride channel
FGM04_11430	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FGM04_11445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGM04_11445	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FGM04_11475	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGM04_11480	COG0564	pseudouridine synthase activity
FGM04_11490	COG0110	maltose O-acetyltransferase activity
FGM04_11495	COG0366	Alpha amylase catalytic
FGM04_11500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_11500	COG1263	PTS System
FGM04_11505	COG1609	Transcriptional regulator
FGM04_11520	COG0252	asparaginase activity
FGM04_11525	COG1253	flavin adenine dinucleotide binding
FGM04_11530	COG0586	Pfam SNARE associated Golgi protein
FGM04_11535	COG1686	Belongs to the peptidase S11 family
FGM04_11570	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FGM04_11575	COG0527	aspartate kinase activity
FGM04_11580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FGM04_11590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FGM04_11595	COG1546	Belongs to the CinA family
FGM04_11600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FGM04_11605	COG4667	esterase of the alpha-beta hydrolase superfamily
FGM04_11615	COG1346	cytolysis
FGM04_11620	COG1380	Effector of murein hydrolase LrgA
FGM04_11625	COG0583	DNA-binding transcription factor activity
FGM04_11635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FGM04_11650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGM04_11655	COG2022	thiamine diphosphate biosynthetic process
FGM04_11665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGM04_11670	COG0352	thiamine-phosphate diphosphorylase activity
FGM04_11675	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FGM04_11695	COG0745	RESPONSE REGULATOR receiver
FGM04_11705	COG0189	ligase activity
FGM04_11750	COG0477	Major facilitator Superfamily
FGM04_11765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FGM04_11770	COG1263	PTS System
FGM04_11770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_11775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FGM04_11780	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FGM04_11790	COG0312	modulator of DNA gyrase
FGM04_11795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FGM04_11810	COG3164	Protein of unknown function
FGM04_11815	COG1530	ribonuclease E activity
FGM04_11820	COG0424	maF-like protein
FGM04_11825	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FGM04_11830	COG1792	Involved in formation and maintenance of cell shape
FGM04_11835	COG1077	Cell shape determining protein MreB Mrl
FGM04_11860	COG4968	Prepilin-type N-terminal cleavage methylation domain
FGM04_11880	COG1459	type II secretion system
FGM04_11885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGM04_11930	COG2200	EAL domain
FGM04_11930	COG2199	diguanylate cyclase activity
FGM04_11935	COG2200	EAL domain
FGM04_11940	COG0387	Pfam Sodium calcium exchanger
FGM04_11945	COG2986	histidine ammonia-lyase
FGM04_11950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FGM04_11955	COG0010	Belongs to the arginase family
FGM04_11960	COG1228	amidohydrolase
FGM04_11965	COG2188	Transcriptional regulator
FGM04_11970	COG0288	reversible hydration of carbon dioxide
FGM04_11980	COG2177	Part of the ABC transporter FtsEX involved in
FGM04_11985	COG2884	Cell division ATP-binding protein ftsE
FGM04_11990	COG0552	protein localization to endoplasmic reticulum
FGM04_11995	COG0742	ribosomal rna small subunit methyltransferase
FGM04_12020	COG2249	NAD(P)H dehydrogenase (quinone) activity
FGM04_12025	COG0583	DNA-binding transcription factor activity
FGM04_12030	COG4221	oxidoreductase activity
FGM04_12045	COG1770	oligopeptidase
FGM04_12060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGM04_12065	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FGM04_12075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGM04_12085	COG2095	MarC family integral membrane protein
FGM04_12095	COG1301	dicarboxylic acid transport
FGM04_12120	COG3714	YhhN family
FGM04_12175	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FGM04_12180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGM04_12185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FGM04_12190	COG0049	tRNA binding
FGM04_12195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FGM04_12200	COG2168	tRNA wobble position uridine thiolation
FGM04_12205	COG2923	Belongs to the DsrF TusC family
FGM04_12210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FGM04_12220	COG2964	Protein conserved in bacteria
FGM04_12225	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FGM04_12230	COG0085	RNA polymerase activity
FGM04_12235	COG0222	ribosome binding
FGM04_12240	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FGM04_12245	COG0081	regulation of translation
FGM04_12250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FGM04_12255	COG0250	Participates in transcription elongation, termination and antitermination
FGM04_12260	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FGM04_12270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FGM04_12295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FGM04_12300	COG0569	domain protein
FGM04_12305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGM04_12335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_12335	COG4191	Histidine kinase
FGM04_12340	COG3005	denitrification pathway
FGM04_12345	COG0243	molybdopterin cofactor binding
FGM04_12355	COG2205	protein histidine kinase activity
FGM04_12360	COG0745	RESPONSE REGULATOR receiver
FGM04_12395	COG2204	response regulator
FGM04_12405	COG2205	protein histidine kinase activity
FGM04_12420	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_12425	COG0516	GMP reductase activity
FGM04_12425	COG0517	IMP dehydrogenase activity
FGM04_12430	COG5413	integral membrane protein
FGM04_12440	COG1522	sequence-specific DNA binding
FGM04_12445	COG2502	aspartate--ammonia ligase
FGM04_12450	COG0542	response to heat
FGM04_12460	COG0564	pseudouridine synthase activity
FGM04_12465	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FGM04_12470	COG0446	pyridine nucleotide-disulphide oxidoreductase
FGM04_12480	COG3681	Belongs to the UPF0597 family
FGM04_12485	COG2964	Protein conserved in bacteria
FGM04_12495	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FGM04_12500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FGM04_12505	COG1979	alcohol dehydrogenase
FGM04_12510	COG2207	Transcriptional regulator
FGM04_12515	COG3040	lipid binding
FGM04_12530	COG0583	DNA-binding transcription factor activity
FGM04_12550	COG0540	Belongs to the ATCase OTCase family
FGM04_12555	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FGM04_12560	COG1438	arginine binding
FGM04_12565	COG1288	antiporter activity
FGM04_12570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FGM04_12595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FGM04_12605	COG3078	GTPase activator activity
FGM04_12620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FGM04_12630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FGM04_12635	COG0408	coproporphyrinogen oxidase activity
FGM04_12640	COG0009	L-threonylcarbamoyladenylate synthase
FGM04_12650	COG0551	DNA topoisomerase type I activity
FGM04_12655	COG2922	Belongs to the Smg family
FGM04_12660	COG0758	DNA mediated transformation
FGM04_12665	COG1652	LysM domain
FGM04_12670	COG0242	peptide deformylase activity
FGM04_12675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FGM04_12680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FGM04_12680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGM04_12685	COG0569	domain protein
FGM04_12690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGM04_12700	COG0174	glutamine synthetase
FGM04_12710	COG3852	Histidine kinase
FGM04_12715	COG2204	response regulator
FGM04_12720	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FGM04_12725	COG1322	Protein conserved in bacteria
FGM04_12745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FGM04_12750	COG0583	DNA-binding transcription factor activity
FGM04_12755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FGM04_12755	COG0519	Catalyzes the synthesis of GMP from XMP
FGM04_12770	COG1396	sequence-specific DNA binding
FGM04_12775	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_12785	COG2962	Rard protein
FGM04_12790	COG0840	transmembrane signaling receptor activity
FGM04_12795	COG2391	methyltransferase activity
FGM04_12810	COG0129	dihydroxy-acid dehydratase activity
FGM04_12815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FGM04_12820	COG3978	acetolactate synthase activity
FGM04_12835	COG0606	chelatase, subunit chli
FGM04_12840	COG0204	Acyl-transferase
FGM04_12845	COG0204	Acyl-transferase
FGM04_12850	COG1683	Conserved Protein
FGM04_12860	COG1335	isochorismatase
FGM04_12875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FGM04_12880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FGM04_12890	COG3084	Protein conserved in bacteria
FGM04_12895	COG2203	Gaf domain
FGM04_12895	COG3706	GGDEF domain
FGM04_12895	COG4251	negative regulation of phosphorylation
FGM04_12895	COG5001	Diguanylate cyclase
FGM04_12910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FGM04_12915	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FGM04_12920	COG1561	YicC-like family, N-terminal region
FGM04_12965	COG3550	peptidyl-serine autophosphorylation
FGM04_12985	COG0583	DNA-binding transcription factor activity
FGM04_13010	COG0385	Bile acid
FGM04_13015	COG0531	amino acid
FGM04_13020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FGM04_13025	COG0531	amino acid
FGM04_13030	COG2731	YhcH YjgK YiaL family protein
FGM04_13035	COG3250	beta-galactosidase activity
FGM04_13040	COG1609	Transcriptional regulator
FGM04_13075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FGM04_13080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGM04_13080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FGM04_13090	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FGM04_13095	COG3074	FtsZ-dependent cytokinesis
FGM04_13105	COG1045	serine acetyltransferase
FGM04_13115	COG0745	RESPONSE REGULATOR receiver
FGM04_13120	COG2205	protein histidine kinase activity
FGM04_13125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FGM04_13130	COG0534	Mate efflux family protein
FGM04_13145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FGM04_13150	COG2937	Belongs to the GPAT DAPAT family
FGM04_13155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FGM04_13160	COG3161	chorismate lyase activity
FGM04_13185	COG0604	alcohol dehydrogenase
FGM04_13190	COG1519	Transferase
FGM04_13195	COG0859	PFAM glycosyl transferase family 9
FGM04_13200	COG0463	Glycosyl transferase, family 2
FGM04_13205	COG0859	PFAM glycosyl transferase family 9
FGM04_13210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FGM04_13215	COG2990	Protein conserved in bacteria
FGM04_13220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FGM04_13230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FGM04_13235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FGM04_13240	COG2003	Belongs to the UPF0758 family
FGM04_13245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FGM04_13250	COG0756	dUTP diphosphatase activity
FGM04_13255	COG1309	transcriptional regulator
FGM04_13260	COG0668	transmembrane transport
FGM04_13265	COG0166	Belongs to the GPI family
FGM04_13270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FGM04_13275	COG0583	DNA-binding transcription factor activity
FGM04_13290	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FGM04_13290	COG1042	CoA-binding domain protein
FGM04_13290	COG0045	succinate-CoA ligase (ADP-forming) activity
FGM04_13320	COG2801	Transposase and inactivated derivatives
FGM04_13325	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FGM04_13330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FGM04_13335	COG1739	Uncharacterized protein family UPF0029
FGM04_13340	COG0006	proline dipeptidase activity
FGM04_13345	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGM04_13350	COG1250	3-hydroxyacyl-CoA dehydrogenase
FGM04_13350	COG1024	Enoyl-CoA hydratase
FGM04_13355	COG0183	Belongs to the thiolase family
FGM04_13360	COG0745	RESPONSE REGULATOR receiver
FGM04_13365	COG2205	protein histidine kinase activity
FGM04_13380	COG0425	Belongs to the sulfur carrier protein TusA family
FGM04_13385	COG0251	oxidation-reduction process
FGM04_13390	COG2885	chlorophyll binding
FGM04_13395	COG2818	Glycosylase
FGM04_13400	COG0752	glycyl-tRNA synthetase alpha subunit
FGM04_13405	COG0751	glycine-tRNA ligase activity
FGM04_13410	COG2131	deaminase
FGM04_13420	COG2199	diguanylate cyclase activity
FGM04_13420	COG2202	Pas domain
FGM04_13420	COG2200	EAL domain
FGM04_13435	COG2188	Transcriptional regulator
FGM04_13440	COG3039	Transposase
FGM04_13465	COG1609	Transcriptional regulator
FGM04_13475	COG0559	Belongs to the binding-protein-dependent transport system permease family
FGM04_13495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGM04_13510	COG2960	long-chain fatty acid transporting porin activity
FGM04_13515	COG5001	Diguanylate cyclase
FGM04_13525	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FGM04_13535	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FGM04_13540	COG3118	belongs to the thioredoxin family
FGM04_13545	COG0513	Belongs to the DEAD box helicase family
FGM04_13550	COG0248	Ppx GppA phosphatase
FGM04_13560	COG0742	ribosomal rna small subunit methyltransferase
FGM04_13575	COG3469	chitinase activity
FGM04_13590	COG0084	hydrolase, TatD family'
FGM04_13595	COG0805	protein transport
FGM04_13600	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGM04_13605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FGM04_13610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FGM04_13615	COG3165	ubiquinone biosynthetic process from chorismate
FGM04_13620	COG2226	methyltransferase
FGM04_13625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FGM04_13630	COG0402	S-adenosylhomocysteine deaminase activity
FGM04_13635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FGM04_13670	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FGM04_13675	COG0848	biopolymer transport protein
FGM04_13680	COG0811	peptide transport
FGM04_13685	COG0811	peptide transport
FGM04_13695	COG2771	luxR family
FGM04_13700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FGM04_13705	COG1349	DNA-binding transcription factor activity
FGM04_13710	COG0745	RESPONSE REGULATOR receiver
FGM04_13715	COG2205	protein histidine kinase activity
FGM04_13730	COG4452	Inner membrane protein CreD
FGM04_13735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FGM04_13740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FGM04_13745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FGM04_13750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FGM04_13755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FGM04_13760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FGM04_13765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FGM04_13775	COG0356	it plays a direct role in the translocation of protons across the membrane
FGM04_13785	COG1475	DNA binding
FGM04_13790	COG1192	Involved in chromosome partitioning
FGM04_13795	COG0357	Ribosomal RNA small subunit methyltransferase G
FGM04_13800	COG0445	tRNA wobble uridine modification
FGM04_13805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGM04_13815	COG4615	Cyclic peptide transporter
FGM04_13820	COG1120	ATPase activity
FGM04_13825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FGM04_13835	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FGM04_13840	COG0706	membrane insertase activity
FGM04_13845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FGM04_13850	COG0594	ribonuclease P activity
FGM04_13855	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FGM04_13875	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FGM04_13880	COG0592	DNA-directed DNA polymerase activity
FGM04_13890	COG0187	DNA topoisomerase II activity
FGM04_13900	COG2378	regulation of single-species biofilm formation
FGM04_13910	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FGM04_13915	COG0071	Belongs to the small heat shock protein (HSP20) family
FGM04_13920	COG0071	Belongs to the small heat shock protein (HSP20) family
FGM04_13925	COG3977	Valine--pyruvate aminotransferase
FGM04_13940	COG2814	Major facilitator Superfamily
FGM04_13945	COG0745	RESPONSE REGULATOR receiver
FGM04_13950	COG2205	protein histidine kinase activity
FGM04_13975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGM04_13980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FGM04_13980	COG4191	Histidine kinase
FGM04_13985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_13990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_13995	COG1309	transcriptional regulator
FGM04_14025	COG0561	phosphatase activity
FGM04_14030	COG2267	carboxylic ester hydrolase activity
FGM04_14040	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FGM04_14045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGM04_14050	COG1758	RNA polymerase activity
FGM04_14055	COG0194	GDP metabolic process
FGM04_14065	COG0859	PFAM glycosyl transferase family 9
FGM04_14070	COG3642	lipopolysaccharide core region biosynthetic process
FGM04_14110	COG0589	response to stress
FGM04_14115	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGM04_14120	COG1528	Iron-storage protein
FGM04_14125	COG2081	HI0933 family
FGM04_14130	COG3275	phosphorelay sensor kinase activity
FGM04_14135	COG3279	Response regulator of the LytR AlgR family
FGM04_14140	COG2223	nitrite transmembrane transporter activity
FGM04_14145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FGM04_14150	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FGM04_14165	COG0583	DNA-binding transcription factor activity
FGM04_14170	COG4206	TonB-dependent receptor
FGM04_14210	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FGM04_14215	COG2166	iron-sulfur cluster assembly
FGM04_14220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FGM04_14235	COG3245	cytochrome
FGM04_14240	COG1063	alcohol dehydrogenase
FGM04_14255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FGM04_14280	COG0110	maltose O-acetyltransferase activity
FGM04_14310	COG1280	lysine exporter protein (LysE YggA)
FGM04_14350	COG1943	Transposase
FGM04_14355	COG0210	DNA helicase
FGM04_14395	COG0737	Belongs to the 5'-nucleotidase family
FGM04_14405	COG2239	Acts as a magnesium transporter
FGM04_14410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGM04_14410	COG1648	precorrin-2 dehydrogenase activity
FGM04_14415	COG2116	formate transmembrane transporter activity
FGM04_14420	COG2146	nitrite reductase [NAD(P)H] activity
FGM04_14425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGM04_14430	COG0842	Transport permease protein
FGM04_14435	COG0842	Transport permease protein
FGM04_14440	COG1131	(ABC) transporter
FGM04_14445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_14455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FGM04_14460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FGM04_14470	COG0018	arginyl-trna synthetase
FGM04_14480	COG1595	DNA-templated transcription, initiation
FGM04_14490	COG1968	undecaprenyl-diphosphatase activity
FGM04_14495	COG2017	converts alpha-aldose to the beta-anomer
FGM04_14500	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FGM04_14505	COG1085	galactose-1-phosphate uridylyltransferase
FGM04_14510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGM04_14515	COG1609	Transcriptional regulator
FGM04_14520	COG3250	beta-galactosidase activity
FGM04_14530	COG1129	ABC transporter
FGM04_14535	COG4211	Belongs to the binding-protein-dependent transport system permease family
FGM04_14545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGM04_14560	COG0366	Alpha amylase catalytic
FGM04_14575	COG0443	Heat shock 70 kDa protein
FGM04_14580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGM04_14585	COG3045	CreA protein
FGM04_14600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGM04_14605	COG0174	glutamine synthetase
FGM04_14625	COG3842	ATPase activity
FGM04_14630	COG1176	ABC-type spermidine putrescine transport system, permease component I
FGM04_14635	COG1177	transmembrane transport
FGM04_14640	COG2258	MOSC domain
FGM04_14655	COG2050	protein possibly involved in aromatic compounds catabolism
FGM04_14660	COG0514	ATP-dependent DNA helicase (RecQ)
FGM04_14670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FGM04_14680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FGM04_14685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FGM04_14700	COG0254	rRNA binding
FGM04_14705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FGM04_14715	COG0702	epimerase
FGM04_14720	COG0814	amino acid
FGM04_14725	COG0281	malic enzyme
FGM04_14730	COG1295	ribonuclease BN
FGM04_14735	COG1490	D-aminoacyl-tRNA deacylase activity
FGM04_14740	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FGM04_14745	COG0456	acetyltransferase
FGM04_14755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FGM04_14760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FGM04_14770	COG2610	gluconate transmembrane transporter activity
FGM04_14775	COG3265	gluconokinase activity
FGM04_14780	COG0129	dihydroxy-acid dehydratase activity
FGM04_14785	COG0800	Aldolase
FGM04_14790	COG1609	Transcriptional regulator
FGM04_14800	COG4942	peptidase
FGM04_14805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FGM04_14810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FGM04_14815	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FGM04_14820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FGM04_14825	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FGM04_14825	COG0316	Belongs to the HesB IscA family
FGM04_14830	COG1040	competence protein
FGM04_14835	COG0596	Alpha beta hydrolase
FGM04_14855	COG2183	response to ionizing radiation
FGM04_14860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FGM04_14865	COG0745	RESPONSE REGULATOR receiver
FGM04_14880	COG0051	transcription antitermination factor activity, RNA binding
FGM04_14885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FGM04_14890	COG0088	Forms part of the polypeptide exit tunnel
FGM04_14895	COG0089	rRNA binding
FGM04_14900	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FGM04_14905	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FGM04_14910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FGM04_14915	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FGM04_14920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FGM04_14925	COG0255	Belongs to the universal ribosomal protein uL29 family
FGM04_14930	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FGM04_14935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FGM04_14940	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FGM04_14945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FGM04_14950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FGM04_14955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FGM04_14960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FGM04_14965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FGM04_14970	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FGM04_14975	COG1841	ribosomal large subunit assembly
FGM04_14980	COG0200	Binds to the 23S rRNA
FGM04_14985	COG0201	protein transport
FGM04_14990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FGM04_14995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FGM04_15000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FGM04_15005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FGM04_15010	COG0202	RNA polymerase activity
FGM04_15015	COG0203	ribosomal protein L17
FGM04_15055	COG4771	TonB-dependent receptor
FGM04_15060	COG3706	GGDEF domain
FGM04_15070	COG0745	RESPONSE REGULATOR receiver
FGM04_15090	COG0583	DNA-binding transcription factor activity
FGM04_15100	COG1741	Belongs to the pirin family
FGM04_15105	COG2259	Doxx family
FGM04_15110	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FGM04_15115	COG1074	ATP-dependent DNA helicase activity
FGM04_15120	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FGM04_15135	COG3706	GGDEF domain
FGM04_15170	COG1175	transmembrane transport
FGM04_15180	COG3842	ATPase activity
FGM04_15210	COG2873	o-acetylhomoserine
FGM04_15220	COG4533	DNA binding
FGM04_15225	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FGM04_15240	COG5380	lipid catabolic process
FGM04_15245	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FGM04_15250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FGM04_15275	COG0753	catalase activity
FGM04_15280	COG0454	-acetyltransferase
FGM04_15280	COG0456	acetyltransferase
FGM04_15305	COG2927	DNA polymerase III (CHI subunit)
FGM04_15310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FGM04_15315	COG0795	lipopolysaccharide-transporting ATPase activity
FGM04_15320	COG0795	lipopolysaccharide-transporting ATPase activity
FGM04_15335	COG0582	viral genome integration into host DNA
FGM04_15395	COG0531	amino acid
FGM04_15420	COG1494	fructose-1,6-bisphosphatase
FGM04_15435	COG2959	enzyme of heme biosynthesis
FGM04_15445	COG0181	hydroxymethylbilane synthase activity
FGM04_15450	COG3072	Adenylate cyclase
FGM04_15455	COG0400	carboxylic ester hydrolase activity
FGM04_15460	COG1965	Belongs to the frataxin family
FGM04_15470	COG0019	diaminopimelate decarboxylase activity
FGM04_15475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FGM04_15490	COG1011	Hydrolase
FGM04_15510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FGM04_15515	COG3028	Belongs to the UPF0307 family
FGM04_15535	COG0328	RNA-DNA hybrid ribonuclease activity
FGM04_15575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FGM04_15610	COG0312	modulator of DNA gyrase
FGM04_15620	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FGM04_15625	COG5007	Belongs to the BolA IbaG family
FGM04_15635	COG2854	intermembrane phospholipid transfer
FGM04_15640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FGM04_15645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FGM04_15650	COG1127	ABC transporter
FGM04_15655	COG0517	IMP dehydrogenase activity
FGM04_15655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGM04_15660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FGM04_15665	COG3117	lipopolysaccharide transmembrane transporter activity
FGM04_15670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FGM04_15675	COG1137	ATPase activity
FGM04_15690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_15695	COG1660	Displays ATPase and GTPase activities
FGM04_15700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_15705	COG3711	transcriptional antiterminator
FGM04_15705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_15720	COG3964	amidohydrolase
FGM04_15750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGM04_15755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FGM04_15765	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FGM04_15770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FGM04_15775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FGM04_15780	COG0723	plastoquinol--plastocyanin reductase activity
FGM04_15785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FGM04_15790	COG2857	Cytochrome c1
FGM04_15795	COG0625	glutathione transferase activity
FGM04_15800	COG2969	positive regulation of protein catabolic process
FGM04_15805	COG2823	Periplasmic or secreted lipoprotein
FGM04_15810	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGM04_15815	COG0792	nuclease activity
FGM04_15820	COG3107	peptidoglycan biosynthetic process
FGM04_15825	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FGM04_15835	COG2001	Belongs to the MraZ family
FGM04_15840	COG0275	rRNA processing
FGM04_15845	COG3116	cell division
FGM04_15850	COG0768	penicillin binding
FGM04_15860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FGM04_15865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FGM04_15870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FGM04_15875	COG0772	Belongs to the SEDS family
FGM04_15880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FGM04_15885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGM04_15895	COG0849	cell division
FGM04_15900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FGM04_15905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FGM04_15915	COG0653	protein targeting
FGM04_15925	COG0494	nUDIX hydrolase
FGM04_15930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FGM04_15935	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FGM04_15950	COG1459	type II secretion system
FGM04_15955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGM04_15985	COG2186	Transcriptional regulator
FGM04_15990	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FGM04_15995	COG0508	dehydrogenase complex catalyzes the overall conversion of
FGM04_16000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FGM04_16010	COG0840	transmembrane signaling receptor activity
FGM04_16015	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGM04_16020	COG1049	propionate catabolic process, 2-methylcitrate cycle
FGM04_16025	COG2200	EAL domain
FGM04_16035	COG0523	cobalamin synthesis protein
FGM04_16055	COG0477	Major facilitator Superfamily
FGM04_16070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FGM04_16075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FGM04_16120	COG0165	Argininosuccinate lyase
FGM04_16125	COG0137	argininosuccinate synthase activity
FGM04_16135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FGM04_16140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FGM04_16150	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FGM04_16155	COG0110	maltose O-acetyltransferase activity
FGM04_16165	COG3706	GGDEF domain
FGM04_16170	COG0814	amino acid
FGM04_16175	COG3932	Exopolysaccharide synthesis, ExoD
FGM04_16185	COG3706	GGDEF domain
FGM04_16190	COG0004	ammonium transporteR
FGM04_16195	COG3133	Outer membrane lipoprotein
FGM04_16200	COG0456	acetyltransferase
FGM04_16225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FGM04_16240	COG0671	phosphoesterase, PA-phosphatase related
FGM04_16245	COG0628	permease
FGM04_16270	COG3284	Transcriptional regulator
FGM04_16285	COG1461	Dihydroxyacetone kinase
FGM04_16290	COG2376	Dihydroxyacetone kinase
FGM04_16295	COG2252	PERMEase
FGM04_16300	COG1278	Cold shock
FGM04_16310	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FGM04_16330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FGM04_16340	COG2194	sulfuric ester hydrolase activity
FGM04_16350	COG3039	Transposase
FGM04_16375	COG2197	response regulator
FGM04_16390	COG1462	curli production assembly transport component CsgG
FGM04_16410	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FGM04_16415	COG3706	GGDEF domain
FGM04_16420	COG3047	cAMP biosynthetic process
FGM04_16425	COG0840	transmembrane signaling receptor activity
FGM04_16450	COG3135	benzoate transporter
FGM04_16455	COG1396	sequence-specific DNA binding
FGM04_16495	COG2926	Belongs to the UPF0265 family
FGM04_16505	COG0561	phosphatase activity
FGM04_16515	COG1546	Belongs to the CinA family
FGM04_16515	COG1058	Belongs to the CinA family
FGM04_16525	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FGM04_16535	COG1522	sequence-specific DNA binding
FGM04_16540	COG1368	sulfuric ester hydrolase activity
FGM04_16580	COG4221	oxidoreductase activity
FGM04_16595	COG1979	alcohol dehydrogenase
FGM04_16600	COG1803	Methylglyoxal synthase
FGM04_16625	COG1444	tRNA N-acetyltransferase activity
FGM04_16630	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_16635	COG0835	chemotaxis
FGM04_16635	COG0784	Response regulator, receiver
FGM04_16645	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FGM04_16650	COG2949	membrane
FGM04_16655	COG3291	Pkd domain containing protein
FGM04_16665	COG3039	Transposase
FGM04_16670	COG3539	Fimbrial protein
FGM04_16680	COG3188	usher protein
FGM04_16685	COG3121	Chaperone
FGM04_16690	COG3539	Fimbrial protein
FGM04_16710	COG1441	menaquinone biosynthetic process
FGM04_16715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FGM04_16720	COG0596	Alpha beta hydrolase
FGM04_16725	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FGM04_16730	COG1169	isochorismate synthase
FGM04_16735	COG1575	Belongs to the MenA family. Type 1 subfamily
FGM04_16755	COG0513	Belongs to the DEAD box helicase family
FGM04_16760	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FGM04_16765	COG1988	membrane-bound metal-dependent
FGM04_16770	COG1671	Belongs to the UPF0178 family
FGM04_16790	COG0484	heat shock protein binding
FGM04_16795	COG3263	regulation of cellular component size
FGM04_16800	COG3722	fumarate hydratase activity
FGM04_16805	COG0246	Mannitol dehydrogenase
FGM04_16810	COG2213	PTS system mannitol-specific
FGM04_16810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_16815	COG1560	Kdo2-lipid A biosynthetic process
FGM04_16820	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FGM04_16820	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FGM04_16825	COG1538	Outer membrane efflux protein
FGM04_16830	COG0494	nUDIX hydrolase
FGM04_16835	COG3151	Protein conserved in bacteria
FGM04_16845	COG3150	esterase
FGM04_16850	COG0187	DNA topoisomerase II activity
FGM04_16865	COG3104	oligopeptide transport
FGM04_16900	COG0583	DNA-binding transcription factor activity
FGM04_16905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FGM04_16925	COG0204	Acyl-transferase
FGM04_16930	COG1842	Phage shock protein A
FGM04_16945	COG2827	Endonuclease containing a URI domain
FGM04_16960	COG1573	uracil-dna glycosylase
FGM04_16965	COG0697	spore germination
FGM04_16970	COG0583	DNA-binding transcription factor activity
FGM04_16975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FGM04_16980	COG1121	(ABC) transporter
FGM04_16985	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FGM04_17015	COG0739	heme binding
FGM04_17025	COG3068	Protein conserved in bacteria
FGM04_17035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FGM04_17035	COG3008	intermembrane lipid transfer
FGM04_17040	COG2995	paraquat-inducible protein a
FGM04_17050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_17060	COG2203	Gaf domain
FGM04_17060	COG3706	GGDEF domain
FGM04_17060	COG5001	Diguanylate cyclase
FGM04_17060	COG4251	negative regulation of phosphorylation
FGM04_17065	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FGM04_17075	COG3916	Acyl-homoserine-lactone synthase
FGM04_17080	COG2771	luxR family
FGM04_17090	COG0840	transmembrane signaling receptor activity
FGM04_17095	COG0632	four-way junction helicase activity
FGM04_17100	COG2255	four-way junction helicase activity
FGM04_17110	COG1294	oxidase, subunit
FGM04_17115	COG4890	Cyd operon protein YbgT
FGM04_17120	COG3790	cyd operon protein YbgE
FGM04_17125	COG0824	Thioesterase
FGM04_17130	COG0811	peptide transport
FGM04_17145	COG0823	Involved in the tonB-independent uptake of proteins
FGM04_17150	COG2885	chlorophyll binding
FGM04_17155	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FGM04_17220	COG0733	neurotransmitter:sodium symporter activity
FGM04_17230	COG0733	neurotransmitter:sodium symporter activity
FGM04_17245	COG0561	phosphatase activity
FGM04_17260	COG1522	sequence-specific DNA binding
FGM04_17295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FGM04_17300	COG1640	4-alpha-glucanotransferase
FGM04_17305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FGM04_17315	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FGM04_17320	COG0840	transmembrane signaling receptor activity
FGM04_17325	COG1585	Membrane protein implicated in regulation of membrane protease activity
FGM04_17330	COG0330	HflC and HflK could
FGM04_17335	COG1648	precorrin-2 dehydrogenase activity
FGM04_17335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FGM04_17340	COG0175	sulfate reduction
FGM04_17345	COG2895	sulfate adenylyltransferase (ATP) activity
FGM04_17350	COG0471	metal ion transport
FGM04_17350	COG3273	potassium ion transport
FGM04_17355	COG0529	Catalyzes the synthesis of activated sulfate
FGM04_17390	COG0840	transmembrane signaling receptor activity
FGM04_17425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FGM04_17440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FGM04_17445	COG3437	response regulator, receiver
FGM04_17445	COG0784	Response regulator, receiver
FGM04_17455	COG2076	Multidrug Resistance protein
FGM04_17460	COG2076	Multidrug Resistance protein
FGM04_17465	COG3039	Transposase
FGM04_17475	COG0346	lactoylglutathione lyase activity
FGM04_17480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FGM04_17485	COG1643	Atp-dependent helicase
FGM04_17495	COG1489	DNA binding
FGM04_17500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FGM04_17505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FGM04_17515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FGM04_17520	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FGM04_17525	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FGM04_17555	COG1924	4 iron, 4 sulfur cluster binding
FGM04_17560	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FGM04_17565	COG0842	Transport permease protein
FGM04_17570	COG1131	(ABC) transporter
FGM04_17585	COG0163	prenyltransferase activity
FGM04_17590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FGM04_17595	COG0671	phosphoesterase, PA-phosphatase related
FGM04_17600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FGM04_17605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_17605	COG1017	nitric oxide dioxygenase activity
FGM04_17610	COG1151	hydroxylamine reductase activity
FGM04_17615	COG0783	Belongs to the Dps family
FGM04_17620	COG3023	N-Acetylmuramoyl-L-alanine amidase
FGM04_17625	COG4807	Protein conserved in bacteria
FGM04_17635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FGM04_17640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FGM04_17645	COG3956	TIGRFAM MazG family protein
FGM04_17650	COG0504	CTP synthase activity
FGM04_17655	COG0148	phosphopyruvate hydratase activity
FGM04_17670	COG2801	Transposase and inactivated derivatives
FGM04_17705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FGM04_17715	COG0488	(ABC) transporter
FGM04_17720	COG0517	IMP dehydrogenase activity
FGM04_17720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FGM04_17735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGM04_17750	COG1794	racemase activity, acting on amino acids and derivatives
FGM04_17760	COG2731	YhcH YjgK YiaL family protein
FGM04_17770	COG0668	transmembrane transport
FGM04_17775	COG1376	ErfK ybiS ycfS ynhG family protein
FGM04_17785	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FGM04_17790	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FGM04_17795	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FGM04_17805	COG0585	pseudouridine synthase activity
FGM04_17810	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FGM04_17815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FGM04_17820	COG1238	metal cluster binding
FGM04_17835	COG1902	pentaerythritol trinitrate reductase activity
FGM04_17845	COG2852	Protein conserved in bacteria
FGM04_17860	COG2957	Belongs to the agmatine deiminase family
FGM04_17865	COG0154	amidase activity
FGM04_17890	COG0513	Belongs to the DEAD box helicase family
FGM04_17895	COG2203	Gaf domain
FGM04_17895	COG2199	diguanylate cyclase activity
FGM04_17905	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
FGM04_17910	COG1858	cytochrome C peroxidase
FGM04_17955	COG2816	NAD+ diphosphatase activity
FGM04_17990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FGM04_17995	COG2252	PERMEase
FGM04_18005	COG0488	(ABC) transporter
FGM04_18020	COG0741	lytic transglycosylase activity
FGM04_18035	COG3416	Protein conserved in bacteria
FGM04_18050	COG4608	Belongs to the ABC transporter superfamily
FGM04_18055	COG0444	Belongs to the ABC transporter superfamily
FGM04_18065	COG4239	(ABC) transporter, permease
FGM04_18070	COG4174	ABC transporter (Permease)
FGM04_18075	COG4206	TonB-dependent receptor
FGM04_18085	COG0811	peptide transport
FGM04_18090	COG0811	peptide transport
FGM04_18095	COG0848	biopolymer transport protein
FGM04_18115	COG3385	transposase activity
FGM04_18125	COG0439	Biotin carboxylase
FGM04_18130	COG0511	ligase activity, forming carbon-carbon bonds
FGM04_18135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FGM04_18140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FGM04_18160	COG3381	protein complex oligomerization
FGM04_18170	COG3005	denitrification pathway
FGM04_18175	COG0745	RESPONSE REGULATOR receiver
FGM04_18185	COG1879	ABC-type sugar transport system periplasmic component
FGM04_18190	COG2205	protein histidine kinase activity
FGM04_18190	COG2198	Histidine kinase
FGM04_18190	COG0784	Response regulator, receiver
FGM04_18200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FGM04_18205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FGM04_18210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGM04_18210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FGM04_18225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FGM04_18230	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FGM04_18235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FGM04_18240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FGM04_18265	COG1047	Peptidyl-prolyl cis-trans
FGM04_18270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FGM04_18280	COG0784	Response regulator, receiver
FGM04_18280	COG0835	chemotaxis
FGM04_18285	COG0429	hydrolase of the alpha beta-hydrolase fold
FGM04_18290	COG3706	GGDEF domain
FGM04_18290	COG2203	Gaf domain
FGM04_18290	COG5001	Diguanylate cyclase
FGM04_18290	COG4251	negative regulation of phosphorylation
FGM04_18295	COG3089	Belongs to the UPF0270 family
FGM04_18300	COG3954	Phosphoribulokinase
FGM04_18315	COG1765	OsmC-like protein
FGM04_18320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FGM04_18345	COG2814	Major facilitator Superfamily
FGM04_18355	COG3655	Transcriptional regulator
FGM04_18365	COG2205	protein histidine kinase activity
FGM04_18365	COG5002	protein histidine kinase activity
FGM04_18365	COG0784	Response regulator, receiver
FGM04_18375	COG3706	GGDEF domain
FGM04_18390	COG3397	chitin binding
FGM04_18435	COG0835	chemotaxis
FGM04_18435	COG0784	Response regulator, receiver
FGM04_18440	COG2755	lipolytic protein G-D-S-L family
FGM04_18445	COG4181	ATPase activity
FGM04_18450	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FGM04_18455	COG1090	epimerase
FGM04_18460	COG2200	EAL domain
FGM04_18465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FGM04_18470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FGM04_18475	COG3171	Protein conserved in bacteria
FGM04_18480	COG2066	Belongs to the glutaminase family
FGM04_18485	COG2897	thiosulfate sulfurtransferase activity
FGM04_18500	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGM04_18510	COG2966	Psort location CytoplasmicMembrane, score
FGM04_18515	COG3610	response to peptide
FGM04_18530	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FGM04_18535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FGM04_18545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FGM04_18560	COG0786	glutamate:sodium symporter activity
FGM04_18565	COG0252	asparaginase activity
FGM04_18570	COG3139	Protein of unknown function (DUF1315)
FGM04_18590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FGM04_18595	COG0321	lipoyl(octanoyl) transferase activity
FGM04_18600	COG2921	Belongs to the UPF0250 family
FGM04_18605	COG1686	Belongs to the peptidase S11 family
FGM04_18610	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FGM04_18615	COG2951	lytic endotransglycosylase activity
FGM04_18620	COG0772	Belongs to the SEDS family
FGM04_18625	COG0768	penicillin binding
FGM04_18630	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FGM04_18635	COG0799	negative regulation of ribosome biogenesis
FGM04_18640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FGM04_18655	COG0495	leucyl-tRNA aminoacylation
FGM04_18660	COG2888	peptidyl-tyrosine sulfation
FGM04_18665	COG0312	modulator of DNA gyrase
FGM04_18675	COG0716	FMN binding
FGM04_18680	COG4974	Belongs to the 'phage' integrase family
FGM04_18685	COG3706	GGDEF domain
FGM04_18685	COG0745	RESPONSE REGULATOR receiver
FGM04_18690	COG1970	mechanosensitive ion channel activity
FGM04_18700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FGM04_18705	COG0789	Transcriptional regulator
FGM04_18710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FGM04_18715	COG4535	Mg2 and Co2 transporter CorC
FGM04_18720	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FGM04_18725	COG1702	phosphate starvation-inducible protein PhoH
FGM04_18730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FGM04_18735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FGM04_18740	COG1335	isochorismatase
FGM04_18750	COG3706	GGDEF domain
FGM04_18755	COG0583	DNA-binding transcription factor activity
FGM04_18780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FGM04_18790	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FGM04_18800	COG0516	GMP reductase activity
FGM04_18810	COG0642	Histidine kinase
FGM04_18815	COG0745	RESPONSE REGULATOR receiver
FGM04_18825	COG4221	oxidoreductase activity
FGM04_18835	COG1022	Amp-dependent synthetase and ligase
FGM04_18850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_18865	COG3214	Protein conserved in bacteria
FGM04_18875	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGM04_18880	COG0700	Nucleoside recognition
FGM04_18885	COG3366	ferrous iron transmembrane transporter activity
FGM04_18890	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FGM04_18895	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FGM04_18900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FGM04_18905	COG1053	succinate dehydrogenase
FGM04_18915	COG0584	glycerophosphoryl diester phosphodiesterase
FGM04_18920	COG3264	Mechanosensitive ion channel
FGM04_18920	COG1511	domain protein
FGM04_18930	COG0739	heme binding
FGM04_18940	COG0583	DNA-binding transcription factor activity
FGM04_18960	COG0583	DNA-binding transcription factor activity
FGM04_18965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FGM04_18995	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FGM04_19000	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FGM04_19010	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FGM04_19015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FGM04_19025	COG0180	Tryptophanyl-tRNA synthetase
FGM04_19040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FGM04_19050	COG1012	belongs to the aldehyde dehydrogenase family
FGM04_19065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FGM04_19075	COG1013	pyruvate-flavodoxin oxidoreductase activity
FGM04_19075	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FGM04_19075	COG0674	pyruvate-flavodoxin oxidoreductase activity
FGM04_19075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FGM04_19080	COG0366	Alpha amylase catalytic
FGM04_19105	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FGM04_19115	COG0471	metal ion transport
FGM04_19115	COG0490	domain, Protein
FGM04_19160	COG0012	GTP binding
FGM04_19165	COG0193	aminoacyl-tRNA hydrolase activity
FGM04_19170	COG0737	Belongs to the 5'-nucleotidase family
FGM04_19175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FGM04_19185	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FGM04_19190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FGM04_19195	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FGM04_19200	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FGM04_19205	COG2890	protein-(glutamine-N5) methyltransferase activity
FGM04_19215	COG2912	Transglutaminase-like superfamily
FGM04_19220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FGM04_19225	COG1301	dicarboxylic acid transport
FGM04_19240	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FGM04_19250	COG3408	Glycogen debranching enzyme
FGM04_19250	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FGM04_19260	COG1881	PFAM PEBP family protein
FGM04_19280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGM04_19290	COG0583	DNA-binding transcription factor activity
FGM04_19295	COG1028	Short-chain dehydrogenase reductase Sdr
FGM04_19300	COG0616	signal peptide processing
FGM04_19305	COG2211	Major facilitator Superfamily
FGM04_19310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FGM04_19320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_19330	COG2200	EAL domain
FGM04_19330	COG2203	Gaf domain
FGM04_19330	COG2199	diguanylate cyclase activity
FGM04_19340	COG3039	Transposase
FGM04_19370	COG3724	N-succinylarginine dihydrolase activity
FGM04_19375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGM04_19385	COG0840	transmembrane signaling receptor activity
FGM04_19405	COG4608	Belongs to the ABC transporter superfamily
FGM04_19410	COG0444	Belongs to the ABC transporter superfamily
FGM04_19415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FGM04_19430	COG2205	protein histidine kinase activity
FGM04_19430	COG0784	Response regulator, receiver
FGM04_19460	COG3220	belongs to the UPF0276 family
FGM04_19490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FGM04_19495	COG1289	transmembrane transporter activity
FGM04_19500	COG0303	'Molybdopterin
FGM04_19505	COG0746	molybdenum cofactor guanylyltransferase activity
FGM04_19515	COG4662	Binding-protein-dependent transport system inner membrane component
FGM04_19525	COG2204	response regulator
FGM04_19530	COG3852	Histidine kinase
FGM04_19540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FGM04_19580	COG3383	formate dehydrogenase (NAD+) activity
FGM04_19580	COG3383	formate dehydrogenase (NAD+) activity
FGM04_19585	COG0437	4 iron, 4 sulfur cluster binding
FGM04_19605	COG0281	malic enzyme
FGM04_19635	COG0531	amino acid
FGM04_19640	COG1752	Esterase of the alpha-beta hydrolase superfamily
FGM04_19645	COG3706	GGDEF domain
FGM04_19650	COG1566	PFAM secretion protein HlyD family protein
FGM04_19660	COG1032	radical SAM domain protein
FGM04_19685	COG0583	DNA-binding transcription factor activity
FGM04_19690	COG0673	inositol 2-dehydrogenase activity
FGM04_19695	COG2920	part of a sulfur-relay system
FGM04_19700	COG1289	transmembrane transporter activity
FGM04_19705	COG0670	Belongs to the BI1 family
FGM04_19720	COG1486	melibiose metabolic process
FGM04_19725	COG1917	Cupin 2, conserved barrel domain protein
FGM04_19725	COG2169	Transcriptional regulator
FGM04_19730	COG1447	Phosphotransferase system cellobiose-specific component IIA
FGM04_19735	COG2723	6-phospho-beta-galactosidase activity
FGM04_19740	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGM04_19745	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FGM04_19755	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FGM04_19765	COG3156	type II secretion system protein K
FGM04_19770	COG4795	General secretion pathway protein
FGM04_19775	COG2165	general secretion pathway protein
FGM04_19785	COG2165	general secretion pathway protein
FGM04_19790	COG1459	type II secretion system
FGM04_19795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FGM04_19805	COG3031	protein transport across the cell outer membrane
FGM04_19815	COG3267	Type II secretory pathway component ExeA
FGM04_19815	COG3409	Peptidoglycan-binding domain 1 protein
FGM04_19820	COG3437	response regulator, receiver
FGM04_19820	COG2770	Histidine kinase
FGM04_19835	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGM04_19840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FGM04_19845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_19855	COG2190	(PTS) system
FGM04_19860	COG3706	GGDEF domain
FGM04_19865	COG3590	peptidase
FGM04_19875	COG3264	Mechanosensitive ion channel
FGM04_19875	COG1196	nuclear chromosome segregation
FGM04_19880	COG0469	pyruvate kinase activity
FGM04_19890	COG3384	dioxygenase
FGM04_19895	COG0419	ATPase involved in DNA repair
FGM04_19900	COG0420	3'-5' exonuclease activity
FGM04_19910	COG2974	May be involved in recombination
FGM04_19915	COG0405	Gamma-glutamyltransferase
FGM04_19925	COG1283	sodium-dependent phosphate transmembrane transporter activity
FGM04_19935	COG0531	amino acid
FGM04_19945	COG0531	amino acid
FGM04_19960	COG1396	sequence-specific DNA binding
FGM04_19960	COG1917	Cupin 2, conserved barrel domain protein
FGM04_19965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FGM04_19995	COG0259	pyridoxamine-phosphate oxidase activity
FGM04_20000	COG0625	glutathione transferase activity
FGM04_20020	COG2850	peptidyl-arginine hydroxylation
FGM04_20025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FGM04_20030	COG2915	High frequency lysogenization protein hflD homolog
FGM04_20035	COG0482	sulfurtransferase activity
FGM04_20045	COG1187	pseudouridine synthase activity
FGM04_20055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_20060	COG2271	Major facilitator Superfamily
FGM04_20065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FGM04_20065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_20065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_20080	COG3039	Transposase
FGM04_20090	COG3039	Transposase
FGM04_20115	COG1609	Transcriptional regulator
FGM04_20120	COG1263	PTS System
FGM04_20120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FGM04_20125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FGM04_20130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FGM04_20140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_20145	COG1960	acyl-CoA dehydrogenase activity
FGM04_20155	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FGM04_20170	COG4983	Phage plasmid primase, P4 family domain protein
FGM04_20190	COG5377	YqaJ viral recombinase family
FGM04_20235	COG2003	Belongs to the UPF0758 family
FGM04_20245	COG3039	Transposase
FGM04_20310	COG3039	Transposase
FGM04_20320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FGM04_20345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FGM04_20385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FGM04_20400	COG1940	carbohydrate kinase activity
FGM04_20405	COG0457	Tetratricopeptide repeat
FGM04_20410	COG0477	Major facilitator Superfamily
FGM04_20410	COG2814	Major facilitator Superfamily
FGM04_20420	COG3383	formate dehydrogenase (NAD+) activity
FGM04_20440	COG3039	Transposase
FGM04_20505	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FGM04_20510	COG2867	negative regulation of translational initiation
FGM04_20520	COG1473	amidohydrolase
FGM04_20525	COG1960	acyl-CoA dehydrogenase activity
FGM04_20530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FGM04_20535	COG0121	glutamine amidotransferase
FGM04_20555	COG0784	Response regulator, receiver
FGM04_20555	COG2205	protein histidine kinase activity
FGM04_20565	COG2197	response regulator
FGM04_20570	COG3850	Histidine kinase
FGM04_20575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FGM04_20580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FGM04_20590	COG0243	molybdopterin cofactor binding
FGM04_20595	COG0437	4 iron, 4 sulfur cluster binding
FGM04_20600	COG0348	domain, Protein
FGM04_20610	COG3005	denitrification pathway
FGM04_20615	COG0521	Mo-molybdopterin cofactor biosynthetic process
FGM04_20620	COG0315	cyclic pyranopterin monophosphate synthase activity
FGM04_20625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FGM04_20630	COG0314	molybdopterin synthase activity
FGM04_20645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FGM04_20650	COG2267	carboxylic ester hydrolase activity
FGM04_20655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FGM04_20660	COG0303	'Molybdopterin
FGM04_20665	COG0302	gtp cyclohydrolase
FGM04_20670	COG0840	transmembrane signaling receptor activity
FGM04_20675	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FGM04_20690	COG2353	YceI-like domain
FGM04_20700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FGM04_20735	COG2195	Cleaves the N-terminal amino acid of tripeptides
FGM04_20745	COG1166	arginine decarboxylase activity
FGM04_20765	COG0814	amino acid
FGM04_20775	COG3681	Belongs to the UPF0597 family
FGM04_20780	COG2964	Protein conserved in bacteria
FGM04_20790	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FGM04_20795	COG1288	antiporter activity
FGM04_20810	COG1280	lysine exporter protein (LysE YggA)
FGM04_20825	COG3263	regulation of cellular component size
FGM04_20835	COG1876	peptidase activity
FGM04_20840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FGM04_20845	COG1393	Belongs to the ArsC family
FGM04_20855	COG3069	C4-dicarboxylate transmembrane transporter activity
FGM04_20860	COG1473	amidohydrolase
FGM04_20870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FGM04_20880	COG0017	Asparaginyl-tRNA synthetase
FGM04_20895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FGM04_20900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FGM04_20905	COG0156	8-amino-7-oxononanoate synthase activity
FGM04_20910	COG1073	alpha beta
FGM04_20910	COG2226	methyltransferase
FGM04_20915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FGM04_20920	COG0501	Belongs to the peptidase M48B family
FGM04_20935	COG1388	LysM domain
FGM04_20935	COG1376	ErfK ybiS ycfS ynhG family protein
FGM04_20945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_20950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_20955	COG0745	RESPONSE REGULATOR receiver
FGM04_20960	COG5000	phosphorelay sensor kinase activity
FGM04_20960	COG5002	protein histidine kinase activity
FGM04_20985	COG0741	lytic transglycosylase activity
FGM04_20985	COG1388	LysM domain
FGM04_20990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FGM04_20995	COG2226	methyltransferase
FGM04_21000	COG0328	RNA-DNA hybrid ribonuclease activity
FGM04_21005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FGM04_21015	COG0784	Response regulator, receiver
FGM04_21015	COG3437	response regulator, receiver
FGM04_21020	COG2375	cellular response to nickel ion
FGM04_21025	COG4771	TonB-dependent receptor
FGM04_21030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_21035	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FGM04_21040	COG1120	ATPase activity
FGM04_21055	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FGM04_21060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FGM04_21085	COG0708	Exodeoxyribonuclease III
FGM04_21115	COG3132	Protein of unknown function, DUF480
FGM04_21120	COG3300	MHYT domain
FGM04_21120	COG5001	Diguanylate cyclase
FGM04_21130	COG2801	Transposase and inactivated derivatives
FGM04_21140	COG2841	Protein conserved in bacteria
FGM04_21150	COG0534	Mate efflux family protein
FGM04_21185	COG1309	transcriptional regulator
FGM04_21220	COG3152	Membrane
FGM04_21235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FGM04_21240	COG0840	transmembrane signaling receptor activity
FGM04_21245	COG1482	cell wall glycoprotein biosynthetic process
FGM04_21250	COG2207	Transcriptional regulator
FGM04_21255	COG0538	isocitrate dehydrogenase activity
FGM04_21265	COG3048	D-serine ammonia-lyase activity
FGM04_21270	COG2610	gluconate transmembrane transporter activity
FGM04_21275	COG0583	DNA-binding transcription factor activity
FGM04_21285	COG0791	NLP P60 protein
FGM04_21290	COG0583	DNA-binding transcription factor activity
FGM04_21295	COG0450	alkyl hydroperoxide reductase
FGM04_21315	COG0500	methyltransferase
FGM04_21320	COG4106	trans-aconitate 2-methyltransferase activity
FGM04_21325	COG1801	Protein of unknown function DUF72
FGM04_21335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FGM04_21340	COG0217	transcriptional regulatory protein
FGM04_21450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FGM04_21500	COG1192	Involved in chromosome partitioning
FGM04_21555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FGM04_21570	COG0776	regulation of translation
FGM04_21635	COG2336	PFAM SpoVT AbrB
FGM04_21850	COG1121	(ABC) transporter
FGM04_21875	COG3550	peptidyl-serine autophosphorylation
FGM04_21880	COG1396	sequence-specific DNA binding
FGM04_21885	COG4974	Belongs to the 'phage' integrase family
FGM04_22025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FGM04_22090	COG0714	Associated with various cellular activities
FGM04_22180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process