locus-tag	class	description
HXV88_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HXV88_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HXV88_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HXV88_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HXV88_00025	ENOG4105ECQ	AraC Family Transcriptional Regulator
HXV88_00030	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
HXV88_00035	ENOG4108ZNX	Heat shock protein
HXV88_00040	ENOG4108ZNX	Heat shock protein
HXV88_00045	ENOG4105JKW	Valine--pyruvate aminotransferase
HXV88_00060	ENOG4105C2C	drug resistance transporter, Bcr CflA
HXV88_00065	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HXV88_00070	ENOG4105C08	Histidine kinase
HXV88_00075	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HXV88_00080	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HXV88_00085	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HXV88_00090	ENOG4105DC8	reductase
HXV88_00095	ENOG4105BZU	Histidine kinase
HXV88_00100	ENOG4105BZS	acriflavin resistance protein
HXV88_00105	ENOG410624X	efflux transporter, rnd family, mfp subunit
HXV88_00110	ENOG4105Y7M	Transcriptional regulator, TetR family
HXV88_00140	ENOG4105DQF	Hydrolase
HXV88_00145	ENOG4108EUD	Lysophospholipase
HXV88_00155	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HXV88_00160	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HXV88_00165	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HXV88_00170	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HXV88_00175	ENOG4105DKP	glycosyl transferase, family 9
HXV88_00180	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
HXV88_00190	ENOG4105EMK	carboxylate amino acid amine transporter
HXV88_00220	ENOG4108M6U	Universal stress protein A
HXV88_00225	ENOG4105RKW	reductase (By
HXV88_00230	ENOG41090A1	ferritin
HXV88_00235	ENOG4105CBX	hi0933 family
HXV88_00240	ENOG4108HRK	Histidine kinase
HXV88_00245	ENOG4105DY9	regulatoR
HXV88_00250	ENOG4105FCD	Major Facilitator
HXV88_00255	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HXV88_00260	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HXV88_00275	ENOG41063Z6	transcriptional regulator, lysR family
HXV88_00280	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HXV88_00315	ENOG4105CUZ	uba thif-type nad fad binding protein
HXV88_00320	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HXV88_00325	ENOG4105C9B	Cysteine desulfurase
HXV88_00330	ENOG4105C4R	Atp-dependent dna helicase
HXV88_00335	ENOG4105BZU	Histidine kinase
HXV88_00340	ENOG4105MPD	Cytochrome
HXV88_00345	ENOG4105CPQ	Dehydrogenase
HXV88_00350	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HXV88_00355	ENOG41062JF	Transcriptional regulator
HXV88_00360	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HXV88_00380	ENOG4105W1T	Glycosyl Transferase
HXV88_00415	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HXV88_00440	ENOG41061EV	selenium-binding protein YdfZ
HXV88_00460	ENOG4105C4R	Atp-dependent dna helicase
HXV88_00465	ENOG4105DIH	basic membrane
HXV88_00470	ENOG4108JQ9	ABC transporter
HXV88_00475	ENOG4105UIB	(ABC) transporter
HXV88_00485	ENOG4105CJW	magnesium transporter
HXV88_00490	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HXV88_00495	ENOG4107V9H	nitrite transporter
HXV88_00500	ENOG4105WZK	nitrite reductase NADPH small subunit
HXV88_00505	ENOG4107QZF	nitrite reductase NADPH large subunit
HXV88_00510	ENOG4107QWP	ABC-2 type transporter
HXV88_00515	ENOG4107QWP	ABC-2 type transporter
HXV88_00520	ENOG4105CJ1	ABC, transporter
HXV88_00525	ENOG4105D0S	secretion protein (HlyD
HXV88_00535	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HXV88_00540	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HXV88_00550	ENOG4105C75	arginyL-tRNA synthetase
HXV88_00560	ENOG4105K6V	RNA polymerase
HXV88_00570	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HXV88_00575	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HXV88_00580	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HXV88_00585	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HXV88_00590	ENOG4105CMR	udp-glucose 4-epimerase
HXV88_00595	ENOG41060NJ	transcriptional regulator
HXV88_00600	ENOG4105CNT	hydrolase family 2
HXV88_00610	ENOG4105C2J	ABC transporter
HXV88_00615	ENOG4108HWV	)-transporter
HXV88_00620	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_00625	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HXV88_00640	ENOG4107R28	alpha amylase, catalytic region
HXV88_00655	ENOG4105R8A	Heat shock protein
HXV88_00660	ENOG4105C5I	Dehydrogenase
HXV88_00665	ENOG4108RH0	Crea protein
HXV88_00680	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HXV88_00685	ENOG4105CFQ	glutamine synthetase
HXV88_00690	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HXV88_00700	ENOG4108HM4	ABC transporter
HXV88_00705	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HXV88_00710	ENOG4105F38	ABC transporter, permease
HXV88_00715	ENOG4105D38	putrescine abc transporter
HXV88_00720	ENOG4108RPX	mosc domain containing protein
HXV88_00735	ENOG4108VUY	thioesterase Superfamily protein
HXV88_00740	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HXV88_00745	ENOG4105N7H	Cytochrome
HXV88_00750	ENOG4105CNG	UPF0061 protein
HXV88_00760	ENOG4105EX9	Membrane
HXV88_00765	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HXV88_00770	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_00780	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HXV88_00785	ENOG4105C25	Primosomal protein n'
HXV88_00795	ENOG4105CGD	Nad-dependent epimerase dehydratase
HXV88_00800	ENOG4105CIC	tryptophan-specific transport protein
HXV88_00805	ENOG4105C6K	Malic enzyme
HXV88_00810	ENOG4107S2Z	UPF0761 membrane protein
HXV88_00815	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HXV88_00820	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HXV88_00825	ENOG4105SUU	thioesterase domain
HXV88_00835	ENOG4105CB5	ATP-dependent DNA helicase recG
HXV88_00840	ENOG4105JIM	Phosphatidylserine synthase
HXV88_00845	ENOG4105C6Z	Gluconate
HXV88_00850	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HXV88_00855	ENOG4105C01	Dihydroxy-acid dehydratase
HXV88_00860	ENOG4108UHU	Aldolase
HXV88_00865	ENOG4105DIQ	Transcriptional regulator
HXV88_00875	ENOG41063SB	peptidase
HXV88_00880	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HXV88_00885	ENOG4107YZP	Rhodanese domain protein
HXV88_00890	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HXV88_00895	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HXV88_00900	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HXV88_00905	ENOG4105MJ2	Competence protein
HXV88_00910	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HXV88_00930	ENOG4105BZM	domain protein
HXV88_00935	ENOG4108RRZ	Transcription elongation factor GreB
HXV88_00945	ENOG4105E0F	Histidine kinase
HXV88_00955	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HXV88_00960	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HXV88_00965	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HXV88_00970	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HXV88_00975	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HXV88_00980	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HXV88_00985	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HXV88_00990	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HXV88_00995	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HXV88_01000	ENOG41083MP	50s ribosomal protein l29
HXV88_01005	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HXV88_01010	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HXV88_01015	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HXV88_01020	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HXV88_01025	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HXV88_01030	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HXV88_01035	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HXV88_01040	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HXV88_01045	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HXV88_01050	ENOG4105VPB	50S ribosomal protein L30
HXV88_01055	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HXV88_01060	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HXV88_01065	ENOG41067V7	50S ribosomal protein L36
HXV88_01070	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HXV88_01075	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HXV88_01080	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HXV88_01085	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HXV88_01090	ENOG4108ZT0	50S ribosomal protein l17
HXV88_01120	ENOG4105D05	Receptor
HXV88_01125	ENOG4105BZU	Histidine kinase
HXV88_01130	ENOG4105E0F	Histidine kinase
HXV88_01145	ENOG4105CWB	LysR family transcriptional Regulator
HXV88_01155	ENOG4105C2I	pirin domain protein
HXV88_01160	ENOG4108VBZ	doxx family
HXV88_01165	ENOG4105DSY	exodeoxyribonuclease V, gamma
HXV88_01170	ENOG4107QKA	exodeoxyribonuclease V beta
HXV88_01175	ENOG4107QYX	exodeoxyribonuclease v alpha
HXV88_01190	ENOG4105BZU	Histidine kinase
HXV88_01220	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HXV88_01230	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HXV88_01260	ENOG4108IQK	o-acetylhomoserine
HXV88_01270	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HXV88_01295	ENOG4107IFA	Lipase (EC 3.1.1.3)
HXV88_01300	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HXV88_01305	ENOG4108UDW	Transcriptional regulator, luxr family
HXV88_01325	ENOG4105CH6	catalase
HXV88_01355	ENOG4105MYG	DNA polymerase iii, chi subunit
HXV88_01360	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HXV88_01365	ENOG4108M8S	permease YjgP YjgQ family protein
HXV88_01370	ENOG4108K5H	permease YjgP YjgQ family protein
HXV88_01400	ENOG41061WM	D-Alanyl-D-Alanine
HXV88_01405	ENOG4107SC7	Inner membrane transporter yjeM
HXV88_01425	ENOG4105CBT	Fructose-1,6-bisphosphatase
HXV88_01440	ENOG4105ECF	c-methyltransferase
HXV88_01445	ENOG41076E6	Uroporphyrinogen-III Synthase
HXV88_01450	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HXV88_01455	ENOG4107T0K	Adenylate cyclase
HXV88_01460	ENOG4106CJB	Phospholipase Carboxylesterase
HXV88_01465	ENOG4105XQ6	frataxin-like protein
HXV88_01475	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HXV88_01480	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HXV88_01490	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HXV88_01495	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HXV88_01505	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HXV88_01515	ENOG4108Z86	Glutamine amidotransferase
HXV88_01520	ENOG4105N42	UPF0307 protein
HXV88_01525	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HXV88_01530	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HXV88_01535	ENOG4105VFK	BolA family
HXV88_01545	ENOG4105E3I	toluene tolerance
HXV88_01550	ENOG4107PE3	Mammalian cell entry related domain protein
HXV88_01555	ENOG4105CY3	ABC transporter, permease
HXV88_01560	ENOG4105DHJ	ABC, transporter
HXV88_01565	ENOG4105C2X	Arabinose 5-phosphate isomerase
HXV88_01575	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
HXV88_01580	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HXV88_01585	ENOG4108IUZ	ABC transporter
HXV88_01590	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HXV88_01595	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HXV88_01600	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HXV88_01605	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HXV88_01610	ENOG41080Z8	PHOSPHOCARRIER protein
HXV88_01630	ENOG41069H0	dihydroorotase EC 3.5.2.3
HXV88_01660	ENOG4105C0H	protease
HXV88_01665	ENOG4105C0H	protease
HXV88_01675	ENOG4105D6Z	AFG1 family ATPase
HXV88_01680	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HXV88_01685	ENOG4108UJD	30S ribosomal protein S9
HXV88_01690	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HXV88_01695	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HXV88_01700	ENOG4105EIX	cytochrome c1
HXV88_01705	ENOG4107MKT	Stringent starvation protein a
HXV88_01710	ENOG4105KB2	stringent starvation protein b
HXV88_01720	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HXV88_01725	ENOG41082RQ	UPF0102 protein
HXV88_01730	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HXV88_01735	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HXV88_01750	ENOG4105DD5	Flagellar motor switch protein
HXV88_01755	ENOG4105CN7	Flagellar biosynthetic protein FliP
HXV88_01760	ENOG4105VS8	Flagellar biosynthetic protein fliq
HXV88_01765	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HXV88_01770	ENOG4105D00	flagellar biosynthetic protein flhB
HXV88_01785	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HXV88_01790	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HXV88_01795	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HXV88_01805	ENOG4108JIR	Flagellum-specific ATP synthase
HXV88_01825	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
HXV88_01830	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HXV88_01835	ENOG4108ZC9	flagellar basal-body rod protein flgc
HXV88_01840	ENOG4105W00	Flagellar hook capping protein
HXV88_01845	ENOG4105BZE	flagellar hook protein, FlgE
HXV88_01850	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HXV88_01855	ENOG4105CGA	flagellar basal-body rod protein FlgG
HXV88_01860	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HXV88_01865	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HXV88_01875	ENOG4105E1Q	flagellar hook-associated protein
HXV88_01880	ENOG4105DTJ	flagellar hook-associated protein
HXV88_01900	ENOG4105I03	Flagellin
HXV88_01905	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
HXV88_01910	ENOG4105MQ3	flagellar protein FliS
HXV88_01935	ENOG4107RD7	Flagellar Motor Protein, MotA
HXV88_01950	ENOG4105E9H	Lytic Murein transglycosylase
HXV88_01955	ENOG4108V6E	Cell division protein mraZ
HXV88_01960	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HXV88_01965	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HXV88_01970	ENOG4105CJN	penicillin-binding protein
HXV88_01975	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HXV88_01980	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HXV88_01985	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HXV88_01990	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HXV88_01995	ENOG4105CNI	cell division protein FtsW
HXV88_02000	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HXV88_02005	ENOG4105DFU	Cell wall formation (By similarity)
HXV88_02010	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HXV88_02015	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HXV88_02020	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HXV88_02025	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HXV88_02035	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HXV88_02040	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HXV88_02045	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HXV88_02050	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HXV88_02060	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HXV88_02065	ENOG4105D7Q	type ii secretion system
HXV88_02070	ENOG4107QHF	type ii secretion system protein e
HXV88_02080	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HXV88_02095	ENOG41073TP	transcriptional regulator
HXV88_02100	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HXV88_02105	ENOG4107QSN	dihydrolipoamide acetyltransferase
HXV88_02110	ENOG4107QN2	dihydrolipoyl dehydrogenase
HXV88_02115	ENOG4105BZU	Histidine kinase
HXV88_02120	ENOG4108N3W	hemolysin secretion protein
HXV88_02125	ENOG4105D78	K07001 NTE family protein
HXV88_02130	ENOG4107QIJ	Aconitate hydratase 2
HXV88_02135	ENOG4105BZU	Histidine kinase
HXV88_02145	ENOG4105CKI	cobalamin synthesis protein
HXV88_02150	ENOG4108IJF	Heavy metal efflux pump, CzcA
HXV88_02165	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HXV88_02175	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HXV88_02180	ENOG4107ZVW	dihydroneopterin aldolase
HXV88_02185	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HXV88_02210	ENOG4105DWD	nucleoside recognition domain protein
HXV88_02215	ENOG4105KWI	UPF0339 protein
HXV88_02280	ENOG4105YB8	TM2 domain containing protein
HXV88_02320	ENOG4108VCD	Chaperone
HXV88_02325	ENOG4105CW0	outer membrane usher protein
HXV88_02335	ENOG4105BZU	Histidine kinase
HXV88_02345	ENOG4105DWD	nucleoside recognition domain protein
HXV88_02365	ENOG4105CH7	arginosuccinase
HXV88_02370	ENOG4105CDH	Citrulline--aspartate ligase
HXV88_02380	ENOG4105CAS	nag kinase
HXV88_02385	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HXV88_02395	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HXV88_02400	ENOG4108Z66	YbaK ebsC protein
HXV88_02410	ENOG4105CMU	LysR family (Transcriptional regulator
HXV88_02420	ENOG41067MG	lrgb family
HXV88_02430	ENOG4108NRW	Phospholipase, patatin family
HXV88_02435	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HXV88_02440	ENOG4107TH8	cina domain protein
HXV88_02445	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HXV88_02455	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HXV88_02460	ENOG4105CFH	Aspartokinase
HXV88_02465	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HXV88_02500	ENOG41061WM	D-Alanyl-D-Alanine
HXV88_02505	ENOG4106W5V	Membrane
HXV88_02515	ENOG4105HDK	L-asparaginase
HXV88_02530	ENOG4105D4X	repressor
HXV88_02535	ENOG4105C5Y	PTS System
HXV88_02540	ENOG4105CG3	alpha amylase, catalytic region
HXV88_02545	ENOG4108UW5	maltose o-acetyltransferase
HXV88_02555	ENOG4105D3G	Pseudouridine synthase
HXV88_02560	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HXV88_02590	ENOG41090HJ	UPF0265 protein
HXV88_02600	ENOG410667J	hydrolase
HXV88_02610	ENOG4108I62	cina-like protein
HXV88_02620	ENOG4105CVG	Homoserine O-transsuccinylase
HXV88_02630	ENOG4108YXU	transcriptional regulator AsnC family
HXV88_02635	ENOG4105E0M	Sulfatase
HXV88_02675	ENOG4105EMU	Dehydrogenase
HXV88_02680	ENOG4105DZW	Dipeptidase
HXV88_02690	ENOG4108I6A	alcohol dehydrogenase
HXV88_02695	ENOG4108Z5K	methylglyoxal synthase
HXV88_02700	ENOG4108UQY	Iron-storage protein
HXV88_02715	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HXV88_02720	ENOG410904N	short-chain dehydrogenase reductase
HXV88_02725	ENOG4107R88	Chemotaxis protein (CheV)
HXV88_02740	ENOG4108UB4	uncharacterized protein ygjQ
HXV88_02745	ENOG4107MM9	BNR Asp-box repeat-containing protein
HXV88_02750	ENOG4105CEY	Amp-dependent synthetase and ligase
HXV88_02755	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
HXV88_02760	ENOG4108IPT	Naphthoate synthase
HXV88_02765	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HXV88_02770	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HXV88_02775	ENOG4105E4F	Isochorismate synthase
HXV88_02780	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HXV88_02805	ENOG4105C1J	atp-dependent rna helicase
HXV88_02810	ENOG4105D9N	nucleoside
HXV88_02815	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
HXV88_02820	ENOG4108UPT	UPF0178 protein
HXV88_02840	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HXV88_02845	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HXV88_02850	ENOG4105E61	Mannitol repressor protein
HXV88_02855	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HXV88_02860	ENOG4105CTS	PTS system mannitol-specific
HXV88_02865	ENOG4105D1S	lipid A biosynthesis
HXV88_02870	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HXV88_02875	ENOG4105DFG	type I secretion outer membrane protein
HXV88_02880	ENOG41087AY	ADP-Ribose pyrophosphatase
HXV88_02885	ENOG4108SX3	cytoplasmic protein
HXV88_02890	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HXV88_02895	ENOG4105IPS	esterase
HXV88_02900	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HXV88_02905	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HXV88_02920	ENOG4105DUX	Transporter
HXV88_02940	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HXV88_02945	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HXV88_02955	ENOG4105C5Q	Transcriptional regulator
HXV88_02960	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HXV88_02980	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HXV88_02985	ENOG41087YS	Phage shock protein A
HXV88_03000	ENOG41082IR	Excinuclease ABC C subunit domain protein
HXV88_03015	ENOG4108RG0	uracil-dna glycosylase
HXV88_03020	ENOG4105DFI	Membrane
HXV88_03025	ENOG4105ETT	transcriptional Regulator, LysR family
HXV88_03030	ENOG4105FAV	ABC, transporter
HXV88_03035	ENOG4105FDK	ABC transporter
HXV88_03040	ENOG4105NXV	High-affinity zinc uptake system protein
HXV88_03060	ENOG4105DR5	peptidase
HXV88_03070	ENOG4105R2J	Conserved Protein
HXV88_03075	ENOG4105VNT	transposase (IS4 family) protein
HXV88_03080	ENOG4108JU6	CBS domain protein
HXV88_03085	ENOG4106KVJ	cytochrome C assembly protein
HXV88_03090	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HXV88_03095	ENOG4105K5M	30s ribosomal protein S16
HXV88_03100	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HXV88_03105	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HXV88_03110	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HXV88_03120	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HXV88_03125	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HXV88_03130	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HXV88_03135	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HXV88_03140	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HXV88_03145	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HXV88_03155	ENOG41063Z6	transcriptional regulator, lysR family
HXV88_03160	ENOG41080HT	Transcriptional regulator, arsr family
HXV88_03165	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HXV88_03170	ENOG4105CJR	Integral membrane protein (MviN
HXV88_03175	ENOG4105DTN	riboflavin biosynthesis protein ribF
HXV88_03180	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HXV88_03185	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HXV88_03190	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HXV88_03195	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HXV88_03240	ENOG4105C4K	Nad synthetase
HXV88_03245	ENOG4108YZA	Nitrogen regulatory protein pii
HXV88_03255	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HXV88_03265	ENOG4106855	Competence protein
HXV88_03270	ENOG4105EYA	deoxyribonuclease
HXV88_03275	ENOG4105D9N	nucleoside
HXV88_03285	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HXV88_03290	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HXV88_03295	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HXV88_03300	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HXV88_03310	ENOG4105EAC	phosphoserine phosphatase
HXV88_03325	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HXV88_03335	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
HXV88_03340	ENOG4105K70	DNA-binding protein
HXV88_03350	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HXV88_03355	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HXV88_03360	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HXV88_03365	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HXV88_03370	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HXV88_03375	ENOG4105DP0	ferredoxin-NADP reductase
HXV88_03400	ENOG4105DQ4	alcohol dehydrogenase
HXV88_03405	ENOG4105W39	Membrane
HXV88_03415	ENOG4105D9M	gamma-glutamylcysteine synthetase
HXV88_03420	ENOG4108IQE	Amp-dependent synthetase and ligase
HXV88_03430	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HXV88_03445	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HXV88_03455	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HXV88_03460	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HXV88_03465	ENOG4108MJ3	acetyltransferase
HXV88_03470	ENOG4105EV4	Multidrug resistance protein mdtH
HXV88_03485	ENOG4108Z9I	-acetyltransferase
HXV88_03490	ENOG4105D9U	N-acetyltransferase
HXV88_03500	ENOG4105D9R	oxidoreductase
HXV88_03510	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HXV88_03515	ENOG4105CSA	Coproporphyrinogen iii oxidase
HXV88_03520	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
HXV88_03530	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HXV88_03535	ENOG4105C12	Phosphoribosylglycinamide synthetase
HXV88_03555	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HXV88_03560	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HXV88_03565	ENOG4105KTH	gatB Yqey
HXV88_03570	ENOG4105VCC	30S ribosomal protein S21
HXV88_03575	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HXV88_03580	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HXV88_03585	ENOG4108IJ0	Aspartate ammonia-lyase
HXV88_03590	ENOG4105FS0	cytoplasmic membrane protein
HXV88_03600	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HXV88_03605	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HXV88_03615	ENOG4105BZU	Histidine kinase
HXV88_03670	ENOG4108IAB	Phoh family
HXV88_03675	ENOG4107T0D	ABC, transporter
HXV88_03685	ENOG4105DP9	ABC transporter
HXV88_03700	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HXV88_03705	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HXV88_03710	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HXV88_03715	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HXV88_03740	ENOG4105C7K	acetolactate synthase
HXV88_03745	ENOG4108ZP8	Acetolactate synthase small subunit
HXV88_03760	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HXV88_03765	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HXV88_03775	ENOG4107V40	secretion protein, HlyD family
HXV88_03805	ENOG4105I93	response regulator
HXV88_03810	ENOG4105DUX	Transporter
HXV88_03815	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HXV88_03820	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HXV88_03825	ENOG4105C6K	Malic enzyme
HXV88_03830	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HXV88_03840	ENOG4105XWI	UPF0304 protein
HXV88_03845	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HXV88_03850	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HXV88_03855	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HXV88_03860	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HXV88_03865	ENOG4107QWK	SAICAR synthetase
HXV88_03875	ENOG4105CR8	Transcriptional regulator
HXV88_03880	ENOG4108Q67	UPF0319 protein
HXV88_03900	ENOG4105BZU	Histidine kinase
HXV88_03905	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HXV88_03915	ENOG4105BZU	Histidine kinase
HXV88_03920	ENOG4105BZU	Histidine kinase
HXV88_03925	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_03930	ENOG4105MDZ	Transcriptional activator rfaH
HXV88_03935	ENOG4105D01	(LipO)protein
HXV88_03940	ENOG4108UMI	ABC transporter, permease
HXV88_03945	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HXV88_03960	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HXV88_03965	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HXV88_03970	ENOG4105K8N	protein family UPF0079, ATPase
HXV88_03975	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HXV88_03980	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HXV88_03985	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HXV88_03990	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HXV88_03995	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HXV88_04000	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HXV88_04005	ENOG4107QJR	hflk protein
HXV88_04010	ENOG4105EPW	hflc protein
HXV88_04020	ENOG4105EAH	synthase
HXV88_04025	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HXV88_04030	ENOG4105K46	50S ribosomal protein l27
HXV88_04035	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HXV88_04040	ENOG4105DWD	nucleoside recognition domain protein
HXV88_04055	ENOG4105DEN	Luciferase family
HXV88_04075	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HXV88_04085	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HXV88_04090	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HXV88_04095	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HXV88_04100	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HXV88_04105	ENOG4105EHM	Aminoglycoside phosphotransferase
HXV88_04110	ENOG4108S0S	Nucleotidyl transferase
HXV88_04115	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HXV88_04120	ENOG4105CIN	aminoacyl-histidine dipeptidase
HXV88_04125	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HXV88_04130	ENOG4105V1F	Fermentation respiration switch protein
HXV88_04145	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HXV88_04155	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HXV88_04160	ENOG4105K9H	YciI-like protein
HXV88_04165	ENOG4107835	probably involved in intracellular septation (By similarity)
HXV88_04170	ENOG4105DY8	decarboxylase
HXV88_04175	ENOG4108UT2	hemolysin iii
HXV88_04180	ENOG4105D0C	transport protein
HXV88_04195	ENOG4105BZU	Histidine kinase
HXV88_04200	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
HXV88_04225	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HXV88_04230	ENOG4105CIS	alcohol dehydrogenase
HXV88_04235	ENOG4105HEI	LysR family (Transcriptional regulator
HXV88_04240	ENOG4105CI1	PTS System
HXV88_04245	ENOG4108IA2	Sodium pantothenate symporter
HXV88_04255	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HXV88_04260	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HXV88_04265	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HXV88_04270	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HXV88_04280	ENOG4105BZU	Histidine kinase
HXV88_04290	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
HXV88_04295	ENOG4108EM1	reductase
HXV88_04300	ENOG4105CUW	cytochrome C-TYPE protein
HXV88_04305	ENOG4106WF9	DNA-binding transcriptional regulator TorR
HXV88_04315	ENOG4108SV3	Tmao reductase system periplasmic protein tort
HXV88_04320	ENOG4105BZU	Histidine kinase
HXV88_04330	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HXV88_04335	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HXV88_04340	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HXV88_04355	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HXV88_04360	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HXV88_04365	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HXV88_04370	ENOG4108ZAI	phosphatidylglycerophosphatase a
HXV88_04375	ENOG4108JQ6	ABC transporter
HXV88_04385	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HXV88_04395	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HXV88_04400	ENOG4105CTB	Polyprenyl synthetase
HXV88_04405	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HXV88_04410	ENOG4105E14	MotA TolQ exbB proton channel
HXV88_04415	ENOG4107XSU	flagellar motor protein motb
HXV88_04420	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HXV88_04430	ENOG4105HBR	Rna-binding protein
HXV88_04435	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HXV88_04440	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HXV88_04445	ENOG4105EEI	dihydropteroate synthase
HXV88_04450	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HXV88_04455	ENOG4105CP7	Triose-phosphate isomerase
HXV88_04460	ENOG4105NTZ	Preprotein translocase subunit SecG
HXV88_04475	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HXV88_04480	ENOG4105CHV	Transcription elongation factor NusA
HXV88_04485	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HXV88_04490	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HXV88_04495	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HXV88_04500	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HXV88_04505	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HXV88_04510	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HXV88_04515	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HXV88_04520	ENOG4105BZU	Histidine kinase
HXV88_04525	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_04530	ENOG4108V3W	Chemotaxis protein, CheW
HXV88_04540	ENOG4105CBS	Chea signal transduction histidine kinase
HXV88_04555	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_04560	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HXV88_04570	ENOG4105N14	lysine exporter protein LysE YggA
HXV88_04575	ENOG4105CFP	Peptidase U32
HXV88_04580	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HXV88_04590	ENOG4108ZUW	Major pilin subunit
HXV88_04620	ENOG4105CTD	carboxy-peptidase
HXV88_04645	ENOG4105E1F	short-chain dehydrogenase reductase
HXV88_04655	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_04665	ENOG4108WC9	type VI secretion system effector, hcp1 family
HXV88_04670	ENOG4105CS6	Rhs element vgr protein
HXV88_04715	ENOG4105CQC	Prephenate dehydratase
HXV88_04730	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HXV88_04745	ENOG4107SEY	Conserved Protein
HXV88_04750	ENOG4108XDN	Transcriptional regulator
HXV88_04755	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HXV88_04765	ENOG4107FW0	short-chain dehydrogenase reductase
HXV88_04780	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HXV88_04810	ENOG4105CJ2	(LipO)protein
HXV88_04815	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HXV88_04820	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HXV88_04825	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HXV88_04835	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HXV88_04840	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HXV88_04845	ENOG4105M85	Bola protein
HXV88_04850	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HXV88_04860	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HXV88_04865	ENOG4105EYM	Major Facilitator superfamily
HXV88_04875	ENOG4108VPT	UPF0234 protein
HXV88_04880	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HXV88_04885	ENOG4107S0N	DJ-1 family
HXV88_04895	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HXV88_04900	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_04905	ENOG4105ETT	transcriptional Regulator, LysR family
HXV88_04915	ENOG4105M08	Membrane
HXV88_04920	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HXV88_04930	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HXV88_04935	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HXV88_04940	ENOG4105EWT	decarboxylase family
HXV88_04945	ENOG4105BZU	Histidine kinase
HXV88_04955	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HXV88_04960	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HXV88_04965	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
HXV88_04990	ENOG4105WP7	tRNA pseudouridine synthase C
HXV88_04995	ENOG4105DR9	pseudouridine synthase
HXV88_05000	ENOG4105QDK	Flavodoxin
HXV88_05010	ENOG4107W52	maltose operon periplasmic protein
HXV88_05015	ENOG4105CI1	PTS System
HXV88_05020	ENOG4108T8E	UPF0325 protein
HXV88_05025	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HXV88_05030	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HXV88_05035	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HXV88_05040	ENOG4105CE9	30S ribosomal protein S2
HXV88_05045	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HXV88_05050	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HXV88_05055	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HXV88_05065	ENOG4105KNE	Phosphatidate cytidylyltransferase
HXV88_05070	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HXV88_05075	ENOG4105DZP	Membrane-associated zinc metalloprotease
HXV88_05080	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXV88_05085	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HXV88_05090	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HXV88_05095	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HXV88_05100	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HXV88_05105	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HXV88_05110	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HXV88_05115	ENOG4105C0B	DNA polymerase III (alpha subunit)
HXV88_05120	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HXV88_05130	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HXV88_05135	ENOG4105BZG	amino acid carrier protein
HXV88_05140	ENOG4105F8C	transglutaminase domain-containing protein
HXV88_05150	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HXV88_05165	ENOG4105DUX	Transporter
HXV88_05170	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HXV88_05180	ENOG4105D7Z	glutathione synthase
HXV88_05185	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HXV88_05195	ENOG4105GPY	SprT protein
HXV88_05200	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HXV88_05205	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HXV88_05230	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HXV88_05235	ENOG4105DR5	peptidase
HXV88_05240	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HXV88_05255	ENOG4105C7K	acetolactate synthase
HXV88_05265	ENOG4105EQ2	LysR family Transcriptional regulator
HXV88_05270	ENOG4105C44	Serine transporter
HXV88_05285	ENOG4105EXG	Transcriptional regulator
HXV88_05290	ENOG4105DVH	amino acid
HXV88_05295	ENOG4108M3R	transcriptional activator CadC
HXV88_05300	ENOG4105D5Q	Arginine ornithine antiporter
HXV88_05305	ENOG4105CXN	decarboxylase
HXV88_05310	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HXV88_05320	ENOG4105C9K	Endothelin-converting enzyme 1
HXV88_05325	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HXV88_05330	ENOG4105BZU	Histidine kinase
HXV88_05365	ENOG4107T9C	Alpha amylase catalytic region
HXV88_05395	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HXV88_05400	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HXV88_05410	ENOG4105EN6	Membrane
HXV88_05415	ENOG4105EXN	Sulfate transport protein CysZ
HXV88_05420	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HXV88_05425	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HXV88_05430	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HXV88_05440	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HXV88_05445	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HXV88_05475	ENOG4105J12	Multidrug resistance protein mdtN
HXV88_05480	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
HXV88_05485	ENOG4105D2K	citrate carrier protein
HXV88_05490	ENOG4107R1I	NAD-dependent malic enzyme
HXV88_05495	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HXV88_05500	ENOG4106YYS	transcriptional regulatory protein
HXV88_05505	ENOG4108IPJ	Membrane
HXV88_05520	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HXV88_05525	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HXV88_05530	ENOG4105BZU	Histidine kinase
HXV88_05535	ENOG4105DJH	phosphate
HXV88_05540	ENOG4105ERG	peptidase m48, ste24p
HXV88_05555	ENOG4106N3A	copper homeostasis protein cutc
HXV88_05560	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HXV88_05575	ENOG4105PTV	Nudix Hydrolase
HXV88_05600	ENOG4105BZG	amino acid carrier protein
HXV88_05605	ENOG4108KMH	lipoate-protein ligase a
HXV88_05610	ENOG4105C2W	permease
HXV88_05615	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
HXV88_05620	ENOG4105RKX	Protein of unknown function (DUF2498)
HXV88_05625	ENOG4105UQX	Mate efflux family protein
HXV88_05630	ENOG4105ECQ	AraC Family Transcriptional Regulator
HXV88_05635	ENOG4107R1I	NAD-dependent malic enzyme
HXV88_05640	ENOG4105UYK	outer membrane protein a
HXV88_05650	ENOG4105UYK	outer membrane protein a
HXV88_05665	ENOG4107R7I	amino acid
HXV88_05670	ENOG4105D78	K07001 NTE family protein
HXV88_05675	ENOG4105BZU	Histidine kinase
HXV88_05680	ENOG4105J12	Multidrug resistance protein mdtN
HXV88_05690	ENOG4105CCT	upf0313 protein
HXV88_05725	ENOG4105EP9	oxidoreductase
HXV88_05730	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HXV88_05735	ENOG4105EM2	membrane
HXV88_05740	ENOG4108MN8	Membrane
HXV88_05755	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HXV88_05770	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
HXV88_05840	ENOG4105DT3	PTS system, galactitol-specific IIc component
HXV88_05850	ENOG4105F5W	AtP-binding protein
HXV88_05865	ENOG4108YGG	dna repair protein
HXV88_05905	ENOG4108P8R	
HXV88_05910	ENOG410679B	prophage CP4-57 regulatory protein alpA
HXV88_05940	ENOG4108JJA	ABC, transporter
HXV88_05975	ENOG4107VZP	Hemolysin-type calcium-binding repeat 2 copies family protein
HXV88_05980	ENOG4108WC9	type VI secretion system effector, hcp1 family
HXV88_05985	ENOG4105CS6	Rhs element vgr protein
HXV88_05995	ENOG4105CNA	YD repeat protein
HXV88_06010	ENOG4105DFP	Integrase
HXV88_06020	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
HXV88_06025	ENOG4108K4B	hydrolase
HXV88_06090	ENOG4108VAU	general secretion pathway protein G
HXV88_06095	ENOG4105D7Q	type ii secretion system
HXV88_06100	ENOG4107QHF	type ii secretion system protein e
HXV88_06110	ENOG4108XKW	General secretion pathway protein C
HXV88_06125	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_06145	ENOG4105C6T	cysteine synthase
HXV88_06150	ENOG4105KZ7	phosphocarrier protein hpr
HXV88_06155	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HXV88_06160	ENOG4105C5Y	PTS System
HXV88_06165	ENOG4105BZU	Histidine kinase
HXV88_06170	ENOG4105C9K	Endothelin-converting enzyme 1
HXV88_06180	ENOG4105EGS	Mechanosensitive ion channel
HXV88_06185	ENOG4105CA9	Pyruvate kinase
HXV88_06195	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HXV88_06200	ENOG4105EYH	Exonuclease
HXV88_06205	ENOG4107RH8	nuclease SbcCD subunit D
HXV88_06215	ENOG4105DH7	May be involved in recombination (By similarity)
HXV88_06220	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HXV88_06225	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HXV88_06240	ENOG4105CUB	amino acid
HXV88_06250	ENOG4105CUB	amino acid
HXV88_06255	ENOG4108JPW	Aminotransferase
HXV88_06260	ENOG4105C26	Dehydrogenase
HXV88_06265	ENOG4107VRI	Transcriptional regulator
HXV88_06270	ENOG4105CJP	fad dependent oxidoreductase
HXV88_06290	ENOG4108TEB	UPF0114 protein
HXV88_06300	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HXV88_06310	ENOG4105CPW	cytochrome b561
HXV88_06315	ENOG4108R96	Methyltransferase, YaeB family
HXV88_06335	ENOG4108JJ8	(ABC) transporter
HXV88_06340	ENOG4108JJ9	ABC, transporter
HXV88_06355	ENOG41065U4	response regulator
HXV88_06365	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HXV88_06395	ENOG4105D6J	arsenicaL-resistance protein
HXV88_06400	ENOG4105K89	arsenate reductase
HXV88_06405	ENOG4105D9N	nucleoside
HXV88_06425	ENOG4105S2T	inner membrane protein YbcI
HXV88_06445	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HXV88_06450	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HXV88_06455	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HXV88_06460	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HXV88_06465	ENOG4108EFP	Anthranilate synthase component II
HXV88_06470	ENOG4105CRQ	synthase (Component I)
HXV88_06475	ENOG4105DB7	PHP domain protein
HXV88_06480	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HXV88_06490	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HXV88_06495	ENOG4105FE9	pseudouridine synthase
HXV88_06500	ENOG4105D5K	Hemolysin activator protein
HXV88_06505	ENOG4105CKT	filamentous hemagglutinin
HXV88_06525	ENOG4105C29	acyl-CoA thioesterase
HXV88_06530	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HXV88_06535	ENOG4106FVC	RNA methyltransferase
HXV88_06545	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HXV88_06550	ENOG4105D98	threonine synthase
HXV88_06575	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HXV88_06580	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_06595	ENOG4105VYW	UPF0251 protein
HXV88_06610	ENOG4108IG5	Transcriptional regulator
HXV88_06615	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HXV88_06620	ENOG4105BZS	acriflavin resistance protein
HXV88_06635	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HXV88_06640	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HXV88_06645	ENOG4105D2T	synthase
HXV88_06655	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HXV88_06660	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HXV88_06665	ENOG4105F0R	Cytidylyltransferase
HXV88_06675	ENOG4108UW5	maltose o-acetyltransferase
HXV88_06705	ENOG4105C5E	polysaccharide biosynthesis protein
HXV88_06715	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HXV88_06730	ENOG4105D3Q	Sugar transferase
HXV88_06740	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HXV88_06745	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HXV88_06755	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HXV88_06760	ENOG4108QY5	Ferric enterobactin transport protein
HXV88_06770	ENOG4108YX2	DNA-binding protein
HXV88_06775	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HXV88_06780	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HXV88_06785	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HXV88_06790	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HXV88_06795	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HXV88_06800	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HXV88_06805	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HXV88_06810	ENOG4105CFG	Acts as a chaperone (By similarity)
HXV88_06815	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HXV88_06825	ENOG4105D7K	pfkb domain protein
HXV88_06835	ENOG4108HKT	sucrose-6-phosphate hydrolase
HXV88_06840	ENOG4105WBN	Transcriptional regulator (LacI family
HXV88_06855	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HXV88_06890	ENOG4105EFX	secretion protein, HlyD family
HXV88_06895	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HXV88_06900	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HXV88_06905	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HXV88_06910	ENOG4105BZU	Histidine kinase
HXV88_06915	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
HXV88_06925	ENOG4105K4T	epimerase
HXV88_06930	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HXV88_06935	ENOG4105C0A	alcohol dehydrogenase
HXV88_06940	ENOG4107SXA	Phosphorylase
HXV88_06945	ENOG4105D3G	Pseudouridine synthase
HXV88_06950	ENOG4105DU0	nucleoside hydrolase
HXV88_06965	ENOG4105RX8	Protein of unknown function (DUF1523)
HXV88_06975	ENOG410829K	Lysine exporter protein (Lyse ygga)
HXV88_06990	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HXV88_07005	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HXV88_07010	ENOG4105KUZ	arsenate reductase
HXV88_07015	ENOG4107TII	Recombinase
HXV88_07025	ENOG4105W5Q	DNA repair protein (RadC
HXV88_07075	ENOG4105CEE	C4-dicarboxylate transporter
HXV88_07080	ENOG4105CH2	amidohydrolase
HXV88_07090	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HXV88_07100	ENOG4105C5S	asparaginyl-tRNA synthetase
HXV88_07115	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HXV88_07120	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HXV88_07125	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HXV88_07135	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HXV88_07140	ENOG4105D0M	Protease HtpX homolog
HXV88_07145	ENOG4107SDU	Methyl-accepting chemotaxis
HXV88_07150	ENOG4105QVC	MOSC domain-containing protein
HXV88_07150	ENOG4105QVC	MOSC domain-containing protein
HXV88_07165	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HXV88_07175	ENOG4107SRH	Nad-dependent epimerase dehydratase
HXV88_07180	ENOG4105NAU	thioesterase Superfamily protein
HXV88_07195	ENOG41090BQ	Glutaredoxin
HXV88_07200	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HXV88_07205	ENOG4105CFI	type iii restriction protein res subunit
HXV88_07210	ENOG4105EFX	secretion protein, HlyD family
HXV88_07215	ENOG4105KK7	inner membrane protein YiaW
HXV88_07225	ENOG4108NEV	two component transcriptional regulator, LytTR family
HXV88_07230	ENOG4108HRK	Histidine kinase
HXV88_07235	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_07240	ENOG4105DIJ	Phosphoethanolamine transferase
HXV88_07245	ENOG4105E2R	ROK family
HXV88_07250	ENOG4105CE4	GlcNAc 6-P deacetylase
HXV88_07255	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HXV88_07260	ENOG4105CI1	PTS System
HXV88_07265	ENOG4105E2D	ec 3.2.1.52
HXV88_07270	ENOG4105CX6	glutaminyL-tRNA synthetase
HXV88_07275	ENOG41090R7	Ferric uptake
HXV88_07285	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HXV88_07290	ENOG4105NNH	LexA regulated protein
HXV88_07300	ENOG4105EV9	Alpha Beta Hydrolase
HXV88_07305	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HXV88_07310	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HXV88_07325	ENOG4105CVE	Lytic murein transglycosylase
HXV88_07330	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
HXV88_07335	ENOG4108VGW	abc transporter atp-binding protein
HXV88_07345	ENOG4105VNH	ABC transporter solute-binding protein
HXV88_07355	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HXV88_07365	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HXV88_07375	ENOG4105CFU	surface antigen
HXV88_07380	ENOG4105MA0	exported protein
HXV88_07400	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HXV88_07405	ENOG4105BZU	Histidine kinase
HXV88_07410	ENOG4107SC1	transglycosylase
HXV88_07415	ENOG41060NJ	transcriptional regulator
HXV88_07420	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HXV88_07425	ENOG4105D05	Receptor
HXV88_07430	ENOG4105E4F	Isochorismate synthase
HXV88_07435	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HXV88_07440	ENOG4105WQI	isochorismatase
HXV88_07445	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HXV88_07450	ENOG4105C0W	non-ribosomal peptide synthetase
HXV88_07460	ENOG4107RUY	(E1 component), alpha subunit
HXV88_07465	ENOG4105CPP	Dehydrogenase, E1 component
HXV88_07470	ENOG4107QSN	dihydrolipoamide acetyltransferase
HXV88_07475	ENOG4105VEQ	Cold shock protein
HXV88_07500	ENOG4105E43	Extracellular solute-binding protein, family 5
HXV88_07505	ENOG4105N2W	Transcriptional regulator
HXV88_07515	ENOG4105F1A	Pyruvate formate-lyase
HXV88_07520	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HXV88_07530	ENOG4105DHT	Metal Dependent Phosphohydrolase
HXV88_07535	ENOG4105I08	Pseudouridine synthase
HXV88_07545	ENOG4108J59	Extracellular solute-binding protein, family 5
HXV88_07550	ENOG4108RE9	Phosphodiesterase
HXV88_07565	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
HXV88_07575	ENOG4105BZU	Histidine kinase
HXV88_07580	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HXV88_07585	ENOG4108ZC9	flagellar basal-body rod protein flgc
HXV88_07595	ENOG4105BZE	flagellar hook protein, FlgE
HXV88_07600	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HXV88_07605	ENOG4105CGA	flagellar basal-body rod protein FlgG
HXV88_07610	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HXV88_07615	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HXV88_07620	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HXV88_07630	ENOG4105DTJ	flagellar hook-associated protein
HXV88_07635	ENOG4105CJW	magnesium transporter
HXV88_07640	ENOG4105C9X	ppx gppa phosphatase
HXV88_07645	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HXV88_07650	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HXV88_07665	ENOG4105BZU	Histidine kinase
HXV88_07675	ENOG4107QNR	UPF0135 protein
HXV88_07680	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HXV88_07685	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HXV88_07690	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HXV88_07700	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HXV88_07705	ENOG4108I9X	Isocitrate lyase
HXV88_07710	ENOG4107QP3	malate synthase g
HXV88_07725	ENOG4108Z6B	deaminase
HXV88_07730	ENOG4105C8U	phosphate abc transporter
HXV88_07735	ENOG4105E2Z	phosphate ABC transporter (Permease
HXV88_07740	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HXV88_07750	ENOG4105C37	(CBS) domain
HXV88_07760	ENOG4105C3R	Methionine synthase
HXV88_07765	ENOG4105D5Q	Arginine ornithine antiporter
HXV88_07780	ENOG4105CDA	abc transporter atp-binding protein
HXV88_07785	ENOG4105E5Q	amino acid AbC transporter
HXV88_07790	ENOG4106PMH	Extracellular solute-binding protein family 3
HXV88_07795	ENOG4105BZU	Histidine kinase
HXV88_07800	ENOG4105CXY	transporter
HXV88_07805	ENOG4105BZU	Histidine kinase
HXV88_07810	ENOG4108KX4	response regulator
HXV88_07815	ENOG4105NXH	GreA GreB family elongation factor
HXV88_07835	ENOG4105G6Z	alkaline phosphatase
HXV88_07840	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HXV88_07845	ENOG4105DGU	Histone deacetylase
HXV88_07855	ENOG4105DVT	helicase
HXV88_07875	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HXV88_07885	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HXV88_07890	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HXV88_07925	ENOG4105K59	histidine triad (HIT) protein
HXV88_07930	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_07940	ENOG4105CD3	dihydroorotase
HXV88_07955	ENOG4105CK2	sodium dicarboxylate symporter
HXV88_07960	ENOG4107SDU	Methyl-accepting chemotaxis
HXV88_07975	ENOG4105CKW	Inner membrane protein yedI
HXV88_07980	ENOG4105DPN	Oligoendopeptidase f
HXV88_07985	ENOG4105C2W	permease
HXV88_07990	ENOG4105D0Y	UPF0227 protein
HXV88_07995	ENOG4105CEP	NADH dehydrogenase
HXV88_08005	ENOG4105F1A	Pyruvate formate-lyase
HXV88_08010	ENOG4105BZU	Histidine kinase
HXV88_08015	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HXV88_08025	ENOG4105DN3	alpha-2-macroglobulin domain protein
HXV88_08030	ENOG4108JQB	penicillin-binding protein 1C
HXV88_08040	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HXV88_08050	ENOG4105EN6	Membrane
HXV88_08060	ENOG4105I03	Flagellin
HXV88_08080	ENOG4105MQ3	flagellar protein FliS
HXV88_08110	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HXV88_08120	ENOG4105D2T	synthase
HXV88_08130	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
HXV88_08135	ENOG4105F0R	Cytidylyltransferase
HXV88_08140	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HXV88_08145	ENOG4105C5E	polysaccharide biosynthesis protein
HXV88_08160	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HXV88_08170	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_08175	ENOG4105ECY	inositol monophosphatase
HXV88_08185	ENOG4105CYM	Glutathione S-transferase
HXV88_08190	ENOG4105E5M	Multidrug resistance protein D
HXV88_08195	ENOG4105EJC	lysr family transcriptional regulator
HXV88_08200	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HXV88_08205	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HXV88_08225	ENOG4105D0A	hydroxylase
HXV88_08230	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HXV88_08235	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HXV88_08240	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HXV88_08245	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HXV88_08250	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HXV88_08260	ENOG4105CAQ	asparagine synthetase
HXV88_08270	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HXV88_08275	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
HXV88_08280	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HXV88_08290	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HXV88_08295	ENOG4105EE5	Membrane protein terC
HXV88_08305	ENOG4105CQB	FAD linked oxidase domain protein
HXV88_08315	ENOG4105KA0	thioesterase Superfamily protein
HXV88_08330	ENOG4105BZU	Histidine kinase
HXV88_08335	ENOG4105D3Y	Na H antiporter
HXV88_08340	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HXV88_08345	ENOG4105EYK	Phosphatidylglycerophosphatase B
HXV88_08350	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HXV88_08355	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HXV88_08365	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HXV88_08370	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HXV88_08375	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HXV88_08380	ENOG4108S3P	Sporulation domain protein
HXV88_08385	ENOG4105K8R	UPF0145 protein
HXV88_08395	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HXV88_08400	ENOG410810Y	Sulfite reductase
HXV88_08405	ENOG4107SHJ	sulfite reductase subunit b
HXV88_08410	ENOG4105D5B	Sulfite reductase, subunit A
HXV88_08415	ENOG4108NRW	Phospholipase, patatin family
HXV88_08420	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HXV88_08425	ENOG4107T7U	Sulfatase
HXV88_08435	ENOG4105CFH	Aspartokinase
HXV88_08440	ENOG4107QZM	n-acetylglutamate synthase
HXV88_08445	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HXV88_08625	ENOG4105F2Z	3-oxoadipate enol-lactonase
HXV88_08645	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HXV88_08660	ENOG4105C2C	drug resistance transporter, Bcr CflA
HXV88_08700	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HXV88_08720	ENOG4105F2I	Transposase
HXV88_08735	ENOG4105YB8	TM2 domain containing protein
HXV88_08745	ENOG4105DFP	Integrase
HXV88_08810	ENOG4105CHH	sulfate transporter
HXV88_08865	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HXV88_08900	ENOG4105CS6	Rhs element vgr protein
HXV88_08910	ENOG4105CNA	YD repeat protein
HXV88_08935	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HXV88_08940	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HXV88_08945	ENOG4108JQ2	peptide transport system atp-binding protein
HXV88_08950	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HXV88_08955	ENOG4108EU3	peptide transport system, permease
HXV88_08960	ENOG4108I5W	peptide transport system, permease protein
HXV88_08965	ENOG4108J59	Extracellular solute-binding protein, family 5
HXV88_08970	ENOG4105E51	psp operon transcriptional activator
HXV88_08975	ENOG41087YS	Phage shock protein A
HXV88_08980	ENOG4105YYT	phage shock protein B
HXV88_08990	ENOG4105CM6	amino acid regulated cytosolic protein
HXV88_08995	ENOG4106K28	UPF0283 membrane protein
HXV88_09000	ENOG4105MIR	Phenylalanine 4-monooxygenase
HXV88_09005	ENOG41090A4	Pterin carbinolamine dehydratase
HXV88_09025	ENOG4108KHX	Diguanylate cyclase
HXV88_09030	ENOG41090EK	ompa motb domain protein
HXV88_09035	ENOG4105EE5	Membrane protein terC
HXV88_09045	ENOG4105MH2	YfcL protein
HXV88_09055	ENOG4105C28	cystathionine
HXV88_09065	ENOG4108RYK	Nad-dependent epimerase dehydratase
HXV88_09070	ENOG4105CR8	Transcriptional regulator
HXV88_09075	ENOG41064T2	transcriptional regulator, lysR family
HXV88_09080	ENOG4105DJB	Major Facilitator Superfamily
HXV88_09085	ENOG4105EUB	pirin domain protein
HXV88_09090	ENOG4105CHJ	isochorismatase hydrolase
HXV88_09095	ENOG4105EXG	Transcriptional regulator
HXV88_09100	ENOG4105DZ2	Transcriptional regulator
HXV88_09105	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HXV88_09115	ENOG4108KB2	LysR family Transcriptional regulator
HXV88_09120	ENOG4105CS2	ec 3.2.1.21
HXV88_09125	ENOG4105DDY	UPF0142 protein ycaO
HXV88_09130	ENOG4105TMB	Formate nitrite transporter
HXV88_09135	ENOG4105C6N	Formate acetyltransferase
HXV88_09160	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HXV88_09165	ENOG4105C8P	)-transporter
HXV88_09170	ENOG4105K63	Thioredoxin
HXV88_09175	ENOG4105BZU	Histidine kinase
HXV88_09180	ENOG4105BZ1	(ABC) transporter
HXV88_09185	ENOG4105BZ1	(ABC) transporter
HXV88_09195	ENOG4105WQ3	Rna-binding protein
HXV88_09210	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
HXV88_09240	ENOG4105K5X	acetyltransferase
HXV88_09250	ENOG4105BZN	citrate synthase
HXV88_09260	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HXV88_09265	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HXV88_09270	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HXV88_09275	ENOG4105E33	succinate dehydrogenase
HXV88_09280	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HXV88_09285	ENOG4105C7S	Dehydrogenase
HXV88_09290	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HXV88_09295	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HXV88_09305	ENOG4105CJP	fad dependent oxidoreductase
HXV88_09310	ENOG4107RCV	ABC transporter, permease
HXV88_09320	ENOG4105C4Y	ABC transporter
HXV88_09330	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HXV88_09335	ENOG4108JPW	Aminotransferase
HXV88_09340	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HXV88_09355	ENOG4108DMF	Cytochrome C biogenesis protein
HXV88_09360	ENOG4107QX9	Thiol disulfide interChange protein
HXV88_09365	ENOG4105DA4	cytochrome c-type biogenesis protein
HXV88_09370	ENOG4105DVI	reductase, NrfD
HXV88_09375	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HXV88_09380	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
HXV88_09395	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HXV88_09400	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
HXV88_09405	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
HXV88_09410	ENOG4105K5B	UPF0225 protein
HXV88_09415	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_09420	ENOG4105E2R	ROK family
HXV88_09425	ENOG4106IUH	DTW domain containing protein
HXV88_09430	ENOG4105EJ9	Membrane
HXV88_09435	ENOG4105VP0	transcriptional regulator, lysR family
HXV88_09450	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HXV88_09500	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HXV88_09505	ENOG4105PAD	Hydrolase
HXV88_09520	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HXV88_09525	ENOG4105WD1	Membrane
HXV88_09530	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HXV88_09535	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HXV88_09540	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HXV88_09545	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HXV88_09550	ENOG4105DUM	transcriptional regulator, lysR family
HXV88_09560	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HXV88_09565	ENOG4105D1S	lipid A biosynthesis
HXV88_09580	ENOG4105BZU	Histidine kinase
HXV88_09590	ENOG4105CQ2	DNA polymerase
HXV88_09605	ENOG4108VKG	metal-dependent hydrolase
HXV88_09620	ENOG4105CEE	C4-dicarboxylate transporter
HXV88_09635	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HXV88_09640	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HXV88_09645	ENOG4105D0C	transport protein
HXV88_09660	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HXV88_09670	ENOG4105DQR	SNARE associated Golgi
HXV88_09675	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HXV88_09680	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HXV88_09695	ENOG4108VWS	Yaeq family
HXV88_09710	ENOG4108JUB	Transcriptional regulator
HXV88_09745	ENOG4105W1I	UPF0253 protein
HXV88_09750	ENOG4108R6K	riboflavin synthase, subunit alpha
HXV88_09760	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HXV88_09765	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HXV88_09770	ENOG4108SXK	Transporter Drug Metabolite Exporter family
HXV88_09775	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HXV88_09810	ENOG4105XW2	UPF0263 protein
HXV88_09815	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HXV88_09820	ENOG4108W5H	UPF0263 protein
HXV88_09825	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HXV88_09830	ENOG4107QMS	site-determining protein
HXV88_09835	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HXV88_09840	ENOG4105VNG	YcgL domain-containing protein
HXV88_09845	ENOG4105EJQ	L-serine dehydratase
HXV88_09850	ENOG4105EJQ	L-serine dehydratase
HXV88_09855	ENOG4105NBK	UPF0345 protein
HXV88_09865	ENOG4105CTQ	phosphohexokinase
HXV88_09875	ENOG4107S90	membrAne
HXV88_09880	ENOG4106371	Methyltransferase
HXV88_09885	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HXV88_09890	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HXV88_09895	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HXV88_09900	ENOG4105K6T	rare lipoprotein A
HXV88_09915	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HXV88_09945	ENOG4105IW6	Carbamoyltransferase
HXV88_09950	ENOG4107RCH	Diaminopropionate ammonia-lyase
HXV88_09955	ENOG4107S4Y	M20 DapE family protein YgeY
HXV88_09965	ENOG4105C5B	carbamate kinase
HXV88_09980	ENOG4105EHG	Permease protein
HXV88_09985	ENOG4105S10	periplasmic binding protein
HXV88_09990	ENOG4108Q5Y	Membrane
HXV88_10000	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HXV88_10005	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
HXV88_10010	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
HXV88_10015	ENOG4105BZ8	glutamate synthase
HXV88_10020	ENOG4107UUR	Chlorohydrolase aminohydrolase
HXV88_10025	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
HXV88_10030	ENOG4105C7W	Xanthine dehydrogenase
HXV88_10035	ENOG4105C2W	permease
HXV88_10040	ENOG4107QUY	Guanine deaminase
HXV88_10045	ENOG4105C7N	Xanthine uracil vitamin C permease
HXV88_10050	ENOG4105C7W	Xanthine dehydrogenase
HXV88_10055	ENOG4108HR6	Dehydrogenase
HXV88_10060	ENOG4108UTP	(2Fe-2S)-binding domain protein
HXV88_10065	ENOG4107MBR	17 kDa surface antigen
HXV88_10080	ENOG4105CEY	Amp-dependent synthetase and ligase
HXV88_10085	ENOG4105BZU	Histidine kinase
HXV88_10095	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HXV88_10100	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HXV88_10105	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HXV88_10110	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HXV88_10115	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HXV88_10120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HXV88_10125	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HXV88_10130	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HXV88_10140	ENOG4105DVT	helicase
HXV88_10145	ENOG41072GX	Peptidase M22 Glycoprotease
HXV88_10155	ENOG4108MXF	Alpha Beta Hydrolase
HXV88_10160	ENOG4105CEY	Amp-dependent synthetase and ligase
HXV88_10170	ENOG4105C5X	domain protein
HXV88_10175	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HXV88_10180	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HXV88_10190	ENOG4105FAT	Acyl-transferase
HXV88_10195	ENOG4105DR4	Methyltransferase
HXV88_10200	ENOG4108N3W	hemolysin secretion protein
HXV88_10205	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HXV88_10215	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HXV88_10220	ENOG4105D1F	ATP-binding protein
HXV88_10225	ENOG4105DBI	uridine monophosphokinase
HXV88_10230	ENOG4105DHP	deoxycytidine triphosphate deaminase
HXV88_10235	ENOG4105CJ3	phosphate transporter
HXV88_10240	ENOG4105XZD	Fe-S protein
HXV88_10245	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HXV88_10250	ENOG4105XPH	Ferredoxin
HXV88_10255	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HXV88_10260	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HXV88_10265	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HXV88_10270	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HXV88_10275	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HXV88_10300	ENOG4105C22	threonyL-tRNA synthetase
HXV88_10305	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HXV88_10315	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HXV88_10320	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HXV88_10325	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HXV88_10330	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HXV88_10335	ENOG4105BZU	Histidine kinase
HXV88_10360	ENOG4105BZU	Histidine kinase
HXV88_10365	ENOG4105ETE	Transcriptional regulator (LacI family
HXV88_10370	ENOG4108RVA	ribokinase
HXV88_10375	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HXV88_10380	ENOG4105CNN	ABC, transporter
HXV88_10385	ENOG4105C2J	ABC transporter
HXV88_10390	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HXV88_10420	ENOG4108HM4	ABC transporter
HXV88_10425	ENOG4105D38	putrescine abc transporter
HXV88_10435	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HXV88_10450	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HXV88_10455	ENOG4105Q9Y	Universal stress protein
HXV88_10460	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HXV88_10475	ENOG4105C59	p-type ATPase
HXV88_10485	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HXV88_10500	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HXV88_10510	ENOG4108ZGC	gaf domain protein
HXV88_10515	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HXV88_10520	ENOG4105CN1	protease
HXV88_10525	ENOG4105CD8	aminopeptidase N
HXV88_10535	ENOG4105C7I	Dehydrogenase
HXV88_10540	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HXV88_10545	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HXV88_10555	ENOG4105NRA	50s ribosomal protein l31 type b
HXV88_10560	ENOG4105YK5	50S ribosomal protein L36
HXV88_10565	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HXV88_10575	ENOG4105C5H	ABC transporter
HXV88_10580	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HXV88_10585	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HXV88_10590	ENOG4105DAN	ATP-dependent protease
HXV88_10605	ENOG4105MQ5	zona occludens toxin
HXV88_10655	ENOG4105MQ5	zona occludens toxin
HXV88_10710	ENOG4105X2V	dna damage-inducible protein
HXV88_10715	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
HXV88_10720	ENOG4105PDP	Short chain dehydrogenase
HXV88_10760	ENOG4105DXD	2-methylcitrate dehydratase
HXV88_10765	ENOG4105BZN	citrate synthase
HXV88_10770	ENOG4105CR4	methylisocitrate lyase
HXV88_10780	ENOG4105F1S	paraquat-inducible protein a
HXV88_10785	ENOG4105DY2	Paraquat-inducible protein b
HXV88_10790	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HXV88_10805	ENOG4105F8V	Hydrolase, tatD family
HXV88_10810	ENOG4107QRG	dna polymerase iii
HXV88_10815	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HXV88_10820	ENOG4105HHA	aminodeoxychorismate lyase
HXV88_10825	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HXV88_10830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HXV88_10835	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HXV88_10840	ENOG4105CHR	reductase
HXV88_10845	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HXV88_10850	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HXV88_10855	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HXV88_10860	ENOG4105VGS	50s ribosomal protein l32
HXV88_10865	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HXV88_10870	ENOG4108UHJ	MAF-like protein
HXV88_10880	ENOG4105EI2	Pseudouridine synthase
HXV88_10885	ENOG4105C03	ribonuclease
HXV88_10890	ENOG4105DM4	PTS System
HXV88_10895	ENOG4105DE4	1-phosphofructokinase
HXV88_10900	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HXV88_10905	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HXV88_10910	ENOG4105E0U	tyrosine-specific transport protein
HXV88_10930	ENOG4105C1J	atp-dependent rna helicase
HXV88_10940	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HXV88_10945	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HXV88_10950	ENOG4108DG9	Smr protein MutS2
HXV88_10955	ENOG4105BZU	Histidine kinase
HXV88_10960	ENOG4105CVJ	phosphoglycerate mutase
HXV88_10980	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HXV88_10995	ENOG4105P8F	nudix hydrolase
HXV88_11000	ENOG4105C44	Serine transporter
HXV88_11005	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
HXV88_11010	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HXV88_11015	ENOG4105CYN	Serine protein kinase
HXV88_11020	ENOG4106AKX	UPF0229 protein
HXV88_11025	ENOG4105ED1	spovr family
HXV88_11030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HXV88_11035	ENOG4105CHU	acetyl-coa acetyltransferase
HXV88_11040	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HXV88_11070	ENOG4105EMN	RNA polymerase sigma factor
HXV88_11080	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HXV88_11085	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HXV88_11090	ENOG4105D58	Diguanylate phosphodiesterase
HXV88_11095	ENOG4105CHU	acetyl-coa acetyltransferase
HXV88_11105	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HXV88_11115	ENOG4105CQ7	ATP-dependent helicase
HXV88_11125	ENOG4105DHT	Metal Dependent Phosphohydrolase
HXV88_11130	ENOG4105ENH	Sulfatase
HXV88_11135	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HXV88_11155	ENOG4107QVM	von Willebrand factor, type A
HXV88_11185	ENOG4105C4X	radical SAM domain protein
HXV88_11190	ENOG4105CJB	Exodeoxyribonuclease I
HXV88_11200	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
HXV88_11210	ENOG41067MG	lrgb family
HXV88_11215	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
HXV88_11220	ENOG4105C0F	tryptophanase EC 4.1.99.1
HXV88_11230	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HXV88_11235	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HXV88_11240	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HXV88_11245	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HXV88_11265	ENOG4108RC0	Electron transport protein
HXV88_11280	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HXV88_11295	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HXV88_11300	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HXV88_11305	ENOG4107TDF	Formate hydrogenlyase subunit 4
HXV88_11310	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HXV88_11320	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
HXV88_11325	ENOG4105I6X	formate hydrogenlyase maturation
HXV88_11330	ENOG4108MG9	hydrogenase 3 maturation protease
HXV88_11340	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HXV88_11345	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HXV88_11355	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
HXV88_11360	ENOG4105CQS	hydrogenase expression formation protein HypD
HXV88_11365	ENOG4105C45	hydrogenase expression formation protein (HypE)
HXV88_11370	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
HXV88_11375	ENOG4107RSS	Hydrogenase accessory protein HypB
HXV88_11380	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
HXV88_11385	ENOG4105C3U	ABC transporter
HXV88_11390	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HXV88_11395	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HXV88_11405	ENOG4108WGS	hydrogenase 2-specific chaperone
HXV88_11410	ENOG4108USZ	hydrogenase
HXV88_11415	ENOG4105DPX	Hydrogenase, large subunit
HXV88_11420	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
HXV88_11425	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HXV88_11430	ENOG4105E3S	small subunit
HXV88_11440	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
HXV88_11445	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HXV88_11465	ENOG4107EF8	Glycosyl transferase (Group 1
HXV88_11495	ENOG4105UZW	Tail fiber assembly protein
HXV88_11510	ENOG4108KMV	Glycosyl transferase (Group 1
HXV88_11515	ENOG4107QZ7	Cellulose synthase catalytic subunit
HXV88_11525	ENOG4105CG5	Glycosyl transferase (Group 1
HXV88_11530	ENOG4105F8J	Adenylate Guanylate cyclase
HXV88_11560	ENOG4105BZU	Histidine kinase
HXV88_11565	ENOG4105EQ2	LysR family Transcriptional regulator
HXV88_11580	ENOG4107RTG	Major Facilitator superfamily
HXV88_11595	ENOG4105HF0	Membrane
HXV88_11600	ENOG4105D5Q	Arginine ornithine antiporter
HXV88_11605	ENOG4105CHR	reductase
HXV88_11610	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HXV88_11615	ENOG4105E39	Enoyl-CoA hydratase
HXV88_11620	ENOG4105E39	Enoyl-CoA hydratase
HXV88_11625	ENOG4105C1G	acyl-Coa dehydrogenase
HXV88_11630	ENOG4105C1G	acyl-Coa dehydrogenase
HXV88_11635	ENOG4107QX3	carboxylase
HXV88_11640	ENOG4105E39	Enoyl-CoA hydratase
HXV88_11650	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HXV88_11670	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HXV88_11675	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HXV88_11760	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HXV88_11765	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HXV88_11775	ENOG4105ENX	hydrolase
HXV88_11780	ENOG4105CN8	Transcriptional regulator
HXV88_11785	ENOG4105ENX	hydrolase
HXV88_11800	ENOG4105BZG	amino acid carrier protein
HXV88_11830	ENOG4105ED4	portal protein
HXV88_11835	ENOG41060WC	Enoyl-CoA hydratase
HXV88_11850	ENOG41062QD	Membrane
HXV88_11855	ENOG4107QN1	sodium solute
HXV88_11995	ENOG4108YX2	DNA-binding protein
HXV88_12015	ENOG4105KT5	UmuD protein
HXV88_12020	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HXV88_12170	ENOG4107R08	Integrase
HXV88_12175	ENOG4105C5H	ABC transporter
HXV88_12180	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HXV88_12185	ENOG4105K70	DNA-binding protein
HXV88_12190	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HXV88_12195	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HXV88_12200	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HXV88_12205	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HXV88_12220	ENOG4105D60	lipoprotein releasing system transmembrane protein
HXV88_12225	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HXV88_12230	ENOG4105D60	lipoprotein releasing system transmembrane protein
HXV88_12240	ENOG4108JA2	transcriptioN-repair coupling factor
HXV88_12245	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HXV88_12250	ENOG4107QSI	ABC, transporter
HXV88_12255	ENOG4108IPJ	Membrane
HXV88_12265	ENOG4108BY2	phosphohistidine phosphatase
HXV88_12270	ENOG4107QXK	peptidase
HXV88_12275	ENOG4105FQ6	thiopurine methyltransferase
HXV88_12285	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HXV88_12290	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HXV88_12305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HXV88_12310	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HXV88_12315	ENOG4105DS1	cytochrome b561
HXV88_12320	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HXV88_12325	ENOG4105FDP	GntR family transcriptional regulator
HXV88_12330	ENOG4105DM4	PTS System
HXV88_12335	ENOG4105C8I	hydrolase, family 38
HXV88_12340	ENOG4105CPF	Cell wall formation (By similarity)
HXV88_12350	ENOG4108V06	Glutathione peroxidase
HXV88_12355	ENOG4105C1J	atp-dependent rna helicase
HXV88_12360	ENOG4105D4P	Coproporphyrinogen iii oxidase
HXV88_12365	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_12370	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HXV88_12375	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HXV88_12380	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HXV88_12385	ENOG4105C10	Electron transfer flavoprotein
HXV88_12390	ENOG4105BZJ	Electron transfer flavoprotein
HXV88_12395	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HXV88_12405	ENOG4105QZU	Inner membrane protein YfeZ
HXV88_12415	ENOG4105F3T	(LipO)protein
HXV88_12430	ENOG4105BZU	Histidine kinase
HXV88_12445	ENOG4107RE1	Inosine-guanosine kinase
HXV88_12455	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HXV88_12460	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HXV88_12465	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HXV88_12470	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HXV88_12475	ENOG4105E96	Colicin v production protein
HXV88_12485	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HXV88_12490	ENOG4105D1H	recombination factor protein RarA
HXV88_12495	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HXV88_12500	ENOG4105CNU	cell division protein FtsK
HXV88_12505	ENOG4105EW9	transcriptional regulator AsnC family
HXV88_12510	ENOG4105DCF	alanine dehydrogenase
HXV88_12515	ENOG4105C3M	thioredoxin reductase
HXV88_12520	ENOG4105BZU	Histidine kinase
HXV88_12525	ENOG4107MBR	17 kDa surface antigen
HXV88_12530	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HXV88_12535	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HXV88_12540	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HXV88_12545	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HXV88_12550	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HXV88_12555	ENOG4105VEQ	Cold shock protein
HXV88_12560	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HXV88_12580	ENOG4107EXC	regulatoR
HXV88_12585	ENOG4105JJR	Histidine kinase
HXV88_12595	ENOG4105FF5	Membrane
HXV88_12610	ENOG4108RMJ	sensory transduction regulator
HXV88_12620	ENOG4107104	thymidine kinase
HXV88_12625	ENOG4107S6Z	Na H antiporter
HXV88_12635	ENOG4108WBT	adenosyltransferase
HXV88_12640	ENOG4105VRT	cytoplasmic protein
HXV88_12645	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HXV88_12650	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HXV88_12665	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HXV88_12670	ENOG4105CFV	Tetratricopeptide repeat protein
HXV88_12680	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HXV88_12685	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HXV88_12690	ENOG4105CAT	Cytidine monophosphate kinase
HXV88_12695	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HXV88_12700	ENOG4107R11	Transcriptional regulator
HXV88_12705	ENOG4105DUM	transcriptional regulator, lysR family
HXV88_12710	ENOG4108SC4	)-transporter
HXV88_12725	ENOG4108DBC	nitroreductase
HXV88_12730	ENOG4105CFC	Transporter
HXV88_12735	ENOG4105BZU	Histidine kinase
HXV88_12740	ENOG4105CBN	LysR family transcriptional regulator
HXV88_12745	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_12760	ENOG4108RU0	short-chain dehydrogenase reductase
HXV88_12770	ENOG4107RGM	aldo keto reductase
HXV88_12775	ENOG4105VFU	Rna-binding protein
HXV88_12785	ENOG4105CDA	abc transporter atp-binding protein
HXV88_12790	ENOG4105EAD	ABC transporter
HXV88_12800	ENOG4105EZ7	amino acid ABC transporter
HXV88_12805	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
HXV88_12815	ENOG4105HA9	of methanol dehydrogenase type
HXV88_12830	ENOG4105E14	MotA TolQ exbB proton channel
HXV88_12835	ENOG4105ER2	Ompa motb domain protein
HXV88_12840	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HXV88_12845	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HXV88_12850	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HXV88_12855	ENOG4105GKE	subunit e
HXV88_12860	ENOG4107QIZ	NADH dehydrogenase
HXV88_12865	ENOG4108IEH	NADH dehydrogenase subunit g
HXV88_12870	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HXV88_12875	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HXV88_12880	ENOG4107UFS	subunit j
HXV88_12885	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HXV88_12890	ENOG4105D65	subunit l
HXV88_12895	ENOG4105C8S	subunit m
HXV88_12900	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HXV88_12910	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_12915	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_12920	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HXV88_12925	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HXV88_12930	ENOG4105VPD	cellular component movement
HXV88_12935	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HXV88_12940	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HXV88_12945	ENOG4105N21	Membrane
HXV88_12950	ENOG4105CUT	histidyl-tRNA synthetase
HXV88_12955	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HXV88_12960	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HXV88_12970	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HXV88_12975	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HXV88_12990	ENOG4108ZIT	Ferredoxin, 2FE-2S
HXV88_12995	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HXV88_13000	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HXV88_13005	ENOG4108Z4V	iron-sulfur cluster assembly
HXV88_13010	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HXV88_13015	ENOG4105C3J	Cysteine desulfurase
HXV88_13020	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HXV88_13025	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HXV88_13060	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HXV88_13065	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HXV88_13070	ENOG4105VIE	preprotein translocase, subunit YajC
HXV88_13075	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HXV88_13080	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HXV88_13085	ENOG4105W87	Cbs domain
HXV88_13090	ENOG4105D3R	alkyl hydroperoxide reductase
HXV88_13130	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HXV88_13135	ENOG4108JJA	ABC, transporter
HXV88_13140	ENOG4105N5T	Radical SAM Protein
HXV88_13145	ENOG4105CBC	glutamate synthase
HXV88_13150	ENOG4105BZ8	glutamate synthase
HXV88_13160	ENOG4105C1J	atp-dependent rna helicase
HXV88_13185	ENOG4108ZJT	translation initiation factor, Sui1
HXV88_13245	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HXV88_13255	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HXV88_13265	ENOG4105Y3U	Transglycosylase-associated protein
HXV88_13270	ENOG4105DHQ	Histidine kinase
HXV88_13295	ENOG4108RXX	maleylacetoacetate isomerase
HXV88_13305	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HXV88_13310	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HXV88_13320	ENOG4108W1A	pseudouridine synthase
HXV88_13325	ENOG4106YG3	ABC transporter
HXV88_13330	ENOG4105DSP	amino acid AbC transporter
HXV88_13335	ENOG4106PMH	Extracellular solute-binding protein family 3
HXV88_13340	ENOG4108JEH	abc transporter atp-binding protein
HXV88_13345	ENOG4105DWU	Membrane
HXV88_13350	ENOG4105DYB	Isoaspartyl dipeptidase
HXV88_13355	ENOG4106PMH	Extracellular solute-binding protein family 3
HXV88_13360	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
HXV88_13370	ENOG4105K89	arsenate reductase
HXV88_13380	ENOG4105ERG	peptidase m48, ste24p
HXV88_13405	ENOG4105CSR	polyphosphate kinase 2
HXV88_13410	ENOG4108IJ9	(ABC) transporter
HXV88_13420	ENOG4105D56	permease protein
HXV88_13425	ENOG4107FKK	extracellular solute-binding protein family 1
HXV88_13430	ENOG4106V8H	Nucleoid-associated protein
HXV88_13435	ENOG4105PAN	UPF0352 protein
HXV88_13440	ENOG4105E68	Sulfatase
HXV88_13445	ENOG4105D01	(LipO)protein
HXV88_13460	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HXV88_13465	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HXV88_13475	ENOG4105C85	amino acid
HXV88_13540	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HXV88_13545	ENOG4105WH1	Two component transcriptional regulator luxr family
HXV88_13550	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HXV88_13555	ENOG4105W49	UPF0434 protein
HXV88_13560	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HXV88_13570	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HXV88_13585	ENOG4105CGF	Aromatic amino acid aminotransferase
HXV88_13595	ENOG4105CVI	Transcriptional regulator
HXV88_13600	ENOG4108WFC	UPF0438 protein yifE
HXV88_13605	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
HXV88_13610	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HXV88_13615	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HXV88_13620	ENOG4105E98	transcriptional regulator DeoR family
HXV88_13625	ENOG4105CXY	transporter
HXV88_13630	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HXV88_13635	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HXV88_13640	ENOG41069D7	Methyl-accepting chemotaxis
HXV88_13650	ENOG4105HEI	LysR family (Transcriptional regulator
HXV88_13670	ENOG4105CV8	reductase
HXV88_13680	ENOG4105F27	Major Facilitator
HXV88_13685	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HXV88_13700	ENOG4105E18	UPF0276 protein
HXV88_13720	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HXV88_13725	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HXV88_13730	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HXV88_13740	ENOG4108Q2J	Inner membrane protein YebE
HXV88_13745	ENOG4105NAU	thioesterase Superfamily protein
HXV88_13750	ENOG4106428	Protein of unknown function (DUF2496)
HXV88_13760	ENOG4105DJ2	Major Facilitator Superfamily
HXV88_13765	ENOG4105FE9	pseudouridine synthase
HXV88_13775	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HXV88_13785	ENOG4108R4U	Hnh endonuclease
HXV88_13790	ENOG4105DGN	Electron transport complex
HXV88_13795	ENOG4108R3D	Electron transport complex
HXV88_13805	ENOG4105D6A	Electron transport complex
HXV88_13820	ENOG4105CSM	endonuclease III
HXV88_13825	ENOG4108UYE	Lactoylglutathione lyase
HXV88_13830	ENOG4105EIY	sodium-type flagellar protein motY
HXV88_13860	ENOG4107QS8	(LipO)protein
HXV88_13865	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HXV88_13870	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HXV88_13875	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HXV88_13890	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HXV88_13895	ENOG4105E66	phosphoriboisomerase A
HXV88_13900	ENOG4108JQ1	Dehydrogenase
HXV88_13905	ENOG41080IJ	Diacylglycerol kinase
HXV88_13910	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HXV88_13920	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HXV88_13925	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
HXV88_13940	ENOG4105CZX	twitching motility protein
HXV88_13950	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HXV88_13955	ENOG4105DU1	integral membrane protein, terc
HXV88_13960	ENOG4108JQ7	(ABC) transporter
HXV88_13965	ENOG4105C3U	ABC transporter
HXV88_13970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HXV88_13975	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HXV88_13980	ENOG4107QSI	ABC, transporter
HXV88_13985	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HXV88_13990	ENOG4105C0A	alcohol dehydrogenase
HXV88_13995	ENOG4105CDY	transcriptional regulatory protein
HXV88_14000	ENOG4105C9M	aspartyl-trna synthetase
HXV88_14010	ENOG41081XQ	Conserved Protein
HXV88_14015	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HXV88_14020	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HXV88_14040	ENOG4105D3R	alkyl hydroperoxide reductase
HXV88_14045	ENOG4105C5Q	Transcriptional regulator
HXV88_14050	ENOG4108QBX	(LipO)protein
HXV88_14060	ENOG4105W8I	Transcriptional regulator
HXV88_14070	ENOG4105BZC	d-serine deaminase
HXV88_14080	ENOG4108HMX	isocitrate dehydrogenase (NADP)
HXV88_14085	ENOG4106R3P	AraC family transcriptional regulator
HXV88_14090	ENOG4105EIP	mannose-6-phosphate isomerase
HXV88_14095	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_14100	ENOG4105DM4	PTS System
HXV88_14115	ENOG4105KAF	membrAne
HXV88_14145	ENOG4107RGH	Aldehyde dehydrogenase
HXV88_14150	ENOG4107Z3H	Transcriptional regulator, TetR family
HXV88_14180	ENOG4105UQX	Mate efflux family protein
HXV88_14190	ENOG4105Z2P	Protein of unknown function (DUF465)
HXV88_14200	ENOG4105BZU	Histidine kinase
HXV88_14205	ENOG4108YXG	UPF0502 protein
HXV88_14235	ENOG4105CGK	Exodeoxyribonuclease III
HXV88_14260	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
HXV88_14270	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
HXV88_14275	ENOG4108IJF	Heavy metal efflux pump, CzcA
HXV88_14285	ENOG4105S10	periplasmic binding protein
HXV88_14290	ENOG4105E0A	ABC, transporter
HXV88_14295	ENOG4105TVJ	transport system, permease
HXV88_14300	ENOG4105DQ5	transport system permease protein
HXV88_14305	ENOG4105Q26	Siderophore-interacting protein
HXV88_14310	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_14320	ENOG4107RZZ	dna polymerase iii epsilon subunit
HXV88_14325	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HXV88_14330	ENOG4105D1A	Methyltransferase
HXV88_14335	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HXV88_14340	ENOG4105E9H	Lytic Murein transglycosylase
HXV88_14355	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
HXV88_14365	ENOG4105BZU	Histidine kinase
HXV88_14370	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HXV88_14375	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HXV88_14380	ENOG4105BZS	acriflavin resistance protein
HXV88_14390	ENOG41084CK	capsule polysaccharide
HXV88_14395	ENOG4105E12	capsule polysaccharide
HXV88_14405	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HXV88_14410	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HXV88_14425	ENOG4105C2X	Arabinose 5-phosphate isomerase
HXV88_14430	ENOG4107V1M	polysaccharide export protein
HXV88_14445	ENOG41090SZ	ABC-2 type transporter
HXV88_14465	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HXV88_14475	ENOG4105C8P	)-transporter
HXV88_14485	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
HXV88_14490	ENOG4107TT5	NLP P60 protein
HXV88_14495	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
HXV88_14500	ENOG4107QR8	Thioredoxin
HXV88_14510	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HXV88_14515	ENOG4105CIY	formyltetrahydrofolate deformylase
HXV88_14525	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HXV88_14540	ENOG4105E4C	Lytic transglycosylase catalytic
HXV88_14545	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HXV88_14555	ENOG4105CHM	Aminotransferase
HXV88_14560	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HXV88_14565	ENOG4105RKW	reductase (By
HXV88_14580	ENOG4105WWK	YheO domain protein
HXV88_14585	ENOG4105CEM	UPF0597 protein
HXV88_14590	ENOG4105KME	endoribonuclease L-psp
HXV88_14595	ENOG4105C44	Serine transporter
HXV88_14615	ENOG4105EUZ	Beta-lactamase domain protein
HXV88_14625	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HXV88_14630	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HXV88_14645	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HXV88_14655	ENOG4108YYC	ycei family
HXV88_14660	ENOG4105CC0	LysR family Transcriptional regulator
HXV88_14670	ENOG4105CKU	formyltetrahydrofolate synthetase
HXV88_14675	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_14680	ENOG4105EUJ	GTP cyclohydrolase i
HXV88_14685	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HXV88_14690	ENOG4105D06	uba thif-type nad fad binding protein
HXV88_14705	ENOG41082A2	Alpha beta hydrolase
HXV88_14710	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HXV88_14715	ENOG4105E0C	molybdate abc transporter
HXV88_14720	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HXV88_14725	ENOG4108ZAF	Molybdopterin
HXV88_14730	ENOG4105M00	molybdopterin converting factor, subunit 1
HXV88_14735	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HXV88_14740	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HXV88_14745	ENOG4105CUW	cytochrome C-TYPE protein
HXV88_14755	ENOG4105GXZ	Ferredoxin-type protein NapH
HXV88_14760	ENOG4108BGM	Quinol dehydrogenase periplasmic component
HXV88_14765	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HXV88_14780	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HXV88_14785	ENOG4105BZU	Histidine kinase
HXV88_14790	ENOG4105WH1	Two component transcriptional regulator luxr family
HXV88_14800	ENOG4105BZU	Histidine kinase
HXV88_14810	ENOG4105CHW	UPF0052 protein
HXV88_14820	ENOG4105E7A	Glutamine amidotransferase
HXV88_14825	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HXV88_14830	ENOG4107QPN	acyl-Coa dehydrogenase
HXV88_14835	ENOG4105CH2	amidohydrolase
HXV88_14845	ENOG4108Z1B	Cyclase dehydrase
HXV88_14850	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HXV88_14860	ENOG4105BZU	Histidine kinase
HXV88_14865	ENOG4105BZU	Histidine kinase
HXV88_14870	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HXV88_14910	ENOG4105F5R	ABC transporter
HXV88_14915	ENOG4105CNN	ABC, transporter
HXV88_14920	ENOG4105C2J	ABC transporter
HXV88_14930	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HXV88_14965	ENOG4105W5Q	DNA repair protein (RadC
HXV88_15005	ENOG4108NF7	phage-type endonuclease
HXV88_15050	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_15110	ENOG4107QIV	Cytochrome c biogenesis protein
HXV88_15145	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HXV88_15155	ENOG4105CH6	catalase
HXV88_15165	ENOG4105C4X	radical SAM domain protein
HXV88_15170	ENOG4105ENH	Sulfatase
HXV88_15195	ENOG410679B	prophage CP4-57 regulatory protein alpA
HXV88_15200	ENOG4108P8R	
HXV88_15240	ENOG4108YGG	dna repair protein
HXV88_15275	ENOG4105W5Q	DNA repair protein (RadC
HXV88_15280	ENOG4108Y1S	CRISPR-associated protein, Csy4 family
HXV88_15285	ENOG4105M6W	Crispr-associated protein, Csy3 family
HXV88_15290	ENOG4105DZX	CRISPR-associated protein, Csy2 family
HXV88_15295	ENOG4105ENG	CRISPR-associated protein, Csy1 family
HXV88_15300	ENOG4107IIZ	CRISPR-associated helicase, Cas3
HXV88_15305	ENOG4107SV5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HXV88_15335	ENOG4107SSZ	Phosphatase
HXV88_15345	ENOG4107QPN	acyl-Coa dehydrogenase
HXV88_15350	ENOG4105BZS	acriflavin resistance protein
HXV88_15360	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HXV88_15395	ENOG41066XE	Type III export protein
HXV88_15425	ENOG4108KB1	transcriptional regulator, arac family
HXV88_15440	ENOG4106V6P	Exoenzyme S synthesis protein C
HXV88_15570	ENOG4105C87	Aminotransferase class I and II
HXV88_15575	ENOG4105CI1	PTS System
HXV88_15580	ENOG4107P2S	Transcriptional regulator
HXV88_15590	ENOG4108Z6Z	Transcriptional regulator
HXV88_15630	ENOG4105DM4	PTS System
HXV88_15635	ENOG4105CXY	transporter
HXV88_15640	ENOG4108YRF	PTS System
HXV88_15650	ENOG4108R99	pseudouridine synthase
HXV88_15660	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HXV88_15665	ENOG41075W9	High frequency lysogenization protein HflD homolog
HXV88_15670	ENOG4107QTF	adenylosuccinate lyase
HXV88_15675	ENOG4105EZE	Cupin 4 family protein
HXV88_15695	ENOG4108TGY	Glutathione S-transferase
HXV88_15700	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HXV88_15710	ENOG4105KME	endoribonuclease L-psp
HXV88_15715	ENOG4105C6N	Formate acetyltransferase
HXV88_15720	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HXV88_15725	ENOG4108MST	Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity)
HXV88_15730	ENOG4105C7B	Threonine dehydratase
HXV88_15735	ENOG4105M2J	Glutaredoxin
HXV88_15740	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HXV88_15745	ENOG410903C	(LipO)protein
HXV88_15755	ENOG4105KWW	Biogenesis protein
HXV88_15760	ENOG4107QX9	Thiol disulfide interChange protein
HXV88_15765	ENOG4105DA4	cytochrome c-type biogenesis protein
HXV88_15770	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HXV88_15775	ENOG4105X3C	heme exporter protein
HXV88_15780	ENOG41060IM	Heme exporter protein
HXV88_15785	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HXV88_15800	ENOG4108V3W	Chemotaxis protein, CheW
HXV88_15810	ENOG4107QJE	Chromosome Partitioning Protein
HXV88_15815	ENOG4105ER2	Ompa motb domain protein
HXV88_15820	ENOG4105E14	MotA TolQ exbB proton channel
HXV88_15825	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HXV88_15835	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HXV88_15840	ENOG4108VYJ	response regulator receiver protein
HXV88_15845	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HXV88_15855	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HXV88_15860	ENOG4105D7B	Flagellar biosynthesis protein flha
HXV88_15865	ENOG4105D00	flagellar biosynthetic protein flhB
HXV88_15870	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HXV88_15880	ENOG4105CN7	Flagellar biosynthetic protein FliP
HXV88_15885	ENOG4105VTB	flagellar biosynthesis protein fliO
HXV88_15890	ENOG4105DD5	Flagellar motor switch protein
HXV88_15895	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HXV88_15915	ENOG4108JIR	Flagellum-specific ATP synthase
HXV88_15925	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HXV88_15930	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HXV88_15935	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HXV88_15955	ENOG4105CA9	Pyruvate kinase
HXV88_15960	ENOG4106KNT	transcriptional regulator
HXV88_15965	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HXV88_15990	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_15995	ENOG4106TNF	Periplasmic binding protein
HXV88_16000	ENOG4105C2W	permease
HXV88_16015	ENOG4107R1I	NAD-dependent malic enzyme
HXV88_16035	ENOG4105QAX	Iron-sulfur
HXV88_16040	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HXV88_16040	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HXV88_16075	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HXV88_16085	ENOG4105BZU	Histidine kinase
HXV88_16090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HXV88_16100	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
HXV88_16105	ENOG4108IUZ	ABC transporter
HXV88_16110	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HXV88_16115	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HXV88_16120	ENOG4105DR8	Membrane
HXV88_16125	ENOG4108ESY	Metal dependent phosphohydrolase
HXV88_16135	ENOG4107SDU	Methyl-accepting chemotaxis
HXV88_16165	ENOG4105XIQ	Protein of unknown function (DUF2517)
HXV88_16200	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HXV88_16210	ENOG4108JQ7	(ABC) transporter
HXV88_16220	ENOG4105RD7	BadF BadG BcrA BcrD
HXV88_16225	ENOG4105E2D	ec 3.2.1.52
HXV88_16230	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HXV88_16245	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HXV88_16250	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
HXV88_16275	ENOG4105BZU	Histidine kinase
HXV88_16280	ENOG41068CG	regulatoR
HXV88_16305	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
HXV88_16310	ENOG4105CFP	Peptidase U32
HXV88_16315	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HXV88_16320	ENOG4105WAY	exported protein
HXV88_16325	ENOG41090EX	DsrE family
HXV88_16330	ENOG4105BZU	Histidine kinase
HXV88_16335	ENOG4105E5W	Transporter
HXV88_16340	ENOG4105ERU	peptidase
HXV88_16345	ENOG4105UBK	short-chain dehydrogenase reductase
HXV88_16350	ENOG4105C5Q	Transcriptional regulator
HXV88_16360	ENOG4105C87	Aminotransferase class I and II
HXV88_16375	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HXV88_16380	ENOG4108V1U	phospholipid-binding protein
HXV88_16395	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HXV88_16405	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
HXV88_16410	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HXV88_16415	ENOG41063JG	Transcriptional regulator
HXV88_16425	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HXV88_16430	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HXV88_16435	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HXV88_16440	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HXV88_16445	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HXV88_16455	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HXV88_16460	ENOG4105CGH	5'-nucleotidase
HXV88_16465	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HXV88_16470	ENOG4105C3G	gtp-binding protein
HXV88_16515	ENOG4107QWE	)-transporter
HXV88_16520	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HXV88_16525	ENOG4108I5U	Uridine phosphorylase
HXV88_16535	ENOG41060QA	UPF0267 protein
HXV88_16545	ENOG4105CG3	alpha amylase, catalytic region
HXV88_16550	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
HXV88_16560	ENOG4107VXZ	Hydrolase
HXV88_16575	ENOG4105C26	Dehydrogenase
HXV88_16585	ENOG4105C8Y	Acetylornithine aminotransferase
HXV88_16590	ENOG4105DDQ	anthranilate synthase
HXV88_16600	ENOG4105C31	Tryptophanyl-tRNA synthetase
HXV88_16605	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HXV88_16610	ENOG4105DJV	ribulose-phosphate 3-epimerase
HXV88_16615	ENOG4105DFE	Dna adenine methylase
HXV88_16625	ENOG4105D49	3-dehydroquinate synthase
HXV88_16630	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HXV88_16635	ENOG4105E4G	Type IV pilus
HXV88_16660	ENOG4108JQC	penicillin-binding protein 1A
HXV88_16665	ENOG4105C5Q	Transcriptional regulator
HXV88_16670	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_16685	ENOG4105EJC	lysr family transcriptional regulator
HXV88_16695	ENOG4105DR5	peptidase
HXV88_16705	ENOG4105EGS	Mechanosensitive ion channel
HXV88_16710	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HXV88_16715	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_16725	ENOG4105E33	succinate dehydrogenase
HXV88_16730	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HXV88_16735	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HXV88_16740	ENOG41074DU	domain protein
HXV88_16745	ENOG4108P2H	Inner membrane protein YjiG
HXV88_16750	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HXV88_16760	ENOG4105T0Z	Conserved Protein
HXV88_16775	ENOG4105CJP	fad dependent oxidoreductase
HXV88_16780	ENOG4105CJP	fad dependent oxidoreductase
HXV88_16790	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HXV88_16800	ENOG4108IQE	Amp-dependent synthetase and ligase
HXV88_16810	ENOG4105EMU	Dehydrogenase
HXV88_16820	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HXV88_16825	ENOG4105DHQ	Histidine kinase
HXV88_16835	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HXV88_16845	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HXV88_16855	ENOG4105C5I	Dehydrogenase
HXV88_16865	ENOG4105BZU	Histidine kinase
HXV88_16885	ENOG4106KR7	LysR family Transcriptional regulator
HXV88_16890	ENOG4105BZU	Histidine kinase
HXV88_16895	ENOG4105VEQ	Cold shock protein
HXV88_16900	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HXV88_16905	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HXV88_16910	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HXV88_16915	ENOG4105C9A	Phoh family
HXV88_16920	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HXV88_16925	ENOG4108JU5	Magnesium and cobalt efflux protein
HXV88_16930	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HXV88_16935	ENOG4107SWG	transcriptional regulator MERR family
HXV88_16940	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HXV88_16950	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HXV88_16955	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HXV88_16960	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HXV88_16975	ENOG4107PAI	alpha helical protein
HXV88_16980	ENOG4105C8T	Leucyl-tRNA synthetase
HXV88_16995	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HXV88_17000	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HXV88_17005	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HXV88_17010	ENOG4105CJN	penicillin-binding protein
HXV88_17015	ENOG4105CNI	cell division protein FtsW
HXV88_17020	ENOG4105CVE	Lytic murein transglycosylase
HXV88_17025	ENOG4105K6T	rare lipoprotein A
HXV88_17030	ENOG4105DZ1	carboxypeptidase
HXV88_17035	ENOG4108Z43	UPF0250 protein
HXV88_17040	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HXV88_17045	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HXV88_17065	ENOG4105VUT	cytoplasmic protein
HXV88_17070	ENOG4105HDK	L-asparaginase
HXV88_17075	ENOG4105D6U	Sodium Glutamate Symporter
HXV88_17080	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_17090	ENOG4105CRK	lysyL-tRNA synthetase
HXV88_17095	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HXV88_17100	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HXV88_17105	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HXV88_17115	ENOG4107XM3	UPF0442 protein
HXV88_17120	ENOG4105DWK	Membrane
HXV88_17130	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HXV88_17140	ENOG4105SUV	lipoprotein YgdR
HXV88_17145	ENOG4107RM6	sulfurtransferase
HXV88_17150	ENOG4105CSV	Glutaminase
HXV88_17155	ENOG41090ED	Protein with unknown function (DUF469)
HXV88_17160	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HXV88_17165	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HXV88_17170	ENOG4105BZU	Histidine kinase
HXV88_17175	ENOG4105ECP	epimerase
HXV88_17180	ENOG4105CV6	ABC transporter, permease
HXV88_17185	ENOG4108I0Y	(ABC) transporter
HXV88_17190	ENOG4108UJV	acyl-CoA thioesterase i
HXV88_17235	ENOG4108M1A	Chitin-binding protein
HXV88_17240	ENOG4108MA4	Peptidase M66
HXV88_17250	ENOG4105BZU	Histidine kinase
HXV88_17260	ENOG4105BZU	Histidine kinase
HXV88_17270	ENOG4105VMP	Transcriptional regulator
HXV88_17280	ENOG4105D8G	Major Facilitator superfamily
HXV88_17300	ENOG4105CS6	Rhs element vgr protein
HXV88_17305	ENOG4108WC9	type VI secretion system effector, hcp1 family
HXV88_17335	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HXV88_17340	ENOG41090JE	Utilization Protein
HXV88_17350	ENOG4105EHG	Permease protein
HXV88_17365	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HXV88_17370	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HXV88_17375	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HXV88_17380	ENOG4105CDU	Replicative dna helicase
HXV88_17390	ENOG4105CGH	5'-nucleotidase
HXV88_17410	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HXV88_17415	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HXV88_17425	ENOG41069P5	Protein slyX homolog
HXV88_17430	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HXV88_17435	ENOG4105VKU	nucleicacid-binding protein
HXV88_17450	ENOG4105DNZ	Alpha Beta Hydrolase
HXV88_17460	ENOG4105YP7	UPF0270 protein
HXV88_17465	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HXV88_17480	ENOG4108UKZ	OsmC family
HXV88_17485	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HXV88_17520	ENOG4105DD7	kinase (PfkB family
HXV88_17525	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
HXV88_17570	ENOG4108KW7	amp-dependent synthetase and ligase
HXV88_17575	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HXV88_17585	ENOG4105C84	Histidine ammonia-lyase
HXV88_17610	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HXV88_17615	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HXV88_17620	ENOG4105C2D	reductase
HXV88_17635	ENOG41069NU	Nitroreductase
HXV88_17640	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HXV88_17645	ENOG4105D07	Signal peptide peptidase, SppA
HXV88_17650	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HXV88_17665	ENOG4109015	Biopolymer transport protein exbD tolR
HXV88_17685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HXV88_17690	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HXV88_17695	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HXV88_17710	ENOG4108JQ7	(ABC) transporter
HXV88_17720	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HXV88_17730	ENOG4105G4C	Periplasmic ligand-binding sensor protein
HXV88_17740	ENOG4105E4C	Lytic transglycosylase catalytic
HXV88_17755	ENOG4105C5H	ABC transporter
HXV88_17765	ENOG4105C7N	Xanthine uracil vitamin C permease
HXV88_17770	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HXV88_17775	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_17785	ENOG4105VEQ	Cold shock protein
HXV88_17825	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HXV88_17830	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HXV88_17835	ENOG4105DJ4	phosphatidylserine decarboxylase
HXV88_17840	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HXV88_17860	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HXV88_17865	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HXV88_17875	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HXV88_17880	ENOG4105C3F	Signal peptidase i
HXV88_17885	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HXV88_17895	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HXV88_17900	ENOG41069PW	sigma-e factor negative regulatory protein
HXV88_17905	ENOG4105EMN	RNA polymerase sigma factor
HXV88_17910	ENOG4108IYU	L-aspartate oxidase
HXV88_17920	ENOG4105Y75	tpr repeat protein
HXV88_17925	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HXV88_17950	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HXV88_17970	ENOG4105CJP	fad dependent oxidoreductase
HXV88_17975	ENOG4105D2N	Aldolase
HXV88_17980	ENOG4105BZA	Phosphoglycerate kinase
HXV88_17985	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HXV88_17990	ENOG4105DKQ	ROK family
HXV88_17995	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HXV88_18000	ENOG4105E09	nadh pyrophosphatase
HXV88_18005	ENOG4105C26	Dehydrogenase
HXV88_18010	ENOG4106MWK	domain protein
HXV88_18015	ENOG4105EYW	Ion transport protein
HXV88_18020	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_18030	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HXV88_18065	ENOG4105E09	nadh pyrophosphatase
HXV88_18090	ENOG4107QWG	2-Nitropropane dioxygenase
HXV88_18110	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
HXV88_18120	ENOG4105BZU	Histidine kinase
HXV88_18125	ENOG4105C1J	atp-dependent rna helicase
HXV88_18135	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
HXV88_18155	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HXV88_18160	ENOG4105DWY	Agmatine deiminase
HXV88_18175	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HXV88_18185	ENOG4108K5P	(LipO)protein
HXV88_18190	ENOG4108UM1	dedA family
HXV88_18195	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HXV88_18200	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HXV88_18205	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HXV88_18210	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HXV88_18215	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HXV88_18220	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HXV88_18225	ENOG4105CK7	Sodium proline symporter
HXV88_18235	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HXV88_18240	ENOG4105CUY	Mechanosensitive ion channel
HXV88_18250	ENOG4105XEP	YhcH YjgK YiaL family protein
HXV88_18275	ENOG4107SQD	Transcriptional regulator, GntR family
HXV88_18330	ENOG4105C5H	ABC transporter
HXV88_18340	ENOG4105D6S	protein involved in catabolism of external DNA
HXV88_18385	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HXV88_18390	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HXV88_18395	ENOG4105DXN	mazG family
HXV88_18400	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HXV88_18405	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HXV88_18410	ENOG4105BZU	Histidine kinase
HXV88_18415	ENOG4108W15	Protein of unknown function (DUF1456)
HXV88_18420	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HXV88_18425	ENOG4108RMU	ferritin dps family protein
HXV88_18430	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HXV88_18435	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HXV88_18440	ENOG4105CMR	udp-glucose 4-epimerase
HXV88_18445	ENOG41076MN	Phosphoesterase, PA-phosphatase related
HXV88_18450	ENOG4105DFU	Cell wall formation (By similarity)
HXV88_18455	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HXV88_18460	ENOG410630P	Transcriptional regulator
HXV88_18465	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HXV88_18470	ENOG4105DA5	(ABC) transporter
HXV88_18475	ENOG4105E3A	(ABC) transporter
HXV88_18500	ENOG4108ETY	sodium dicarboxylate symporter
HXV88_18505	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HXV88_18510	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HXV88_18515	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HXV88_18520	ENOG4105DJ0	Poly(A) Polymerase
HXV88_18525	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HXV88_18535	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HXV88_18545	ENOG4105CQ7	ATP-dependent helicase
HXV88_18550	ENOG4105BZ4	penicillin-binding protein
HXV88_18555	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HXV88_18560	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
HXV88_18565	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
HXV88_18575	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HXV88_18580	ENOG4105F0N	pyrophosphate phospho-hydrolase
HXV88_18595	ENOG4108UUE	Transcriptional regulator
HXV88_18610	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HXV88_18630	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HXV88_18640	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HXV88_18650	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HXV88_18655	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HXV88_18660	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HXV88_18665	ENOG4107QX8	SPFH domain, Band 7 family protein
HXV88_18670	ENOG4105G5H	Membrane
HXV88_18675	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_18680	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HXV88_18685	ENOG4105DSB	aldose 1-epimerase
HXV88_18695	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HXV88_18700	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HXV88_18710	ENOG4105E0X	reductase
HXV88_18735	ENOG4105EW9	transcriptional regulator AsnC family
HXV88_18750	ENOG4108K4B	hydrolase
HXV88_18765	ENOG4105C8J	)-transporter
HXV88_18775	ENOG4105C8J	)-transporter
HXV88_18840	ENOG4105UFD	tol-pal system protein YbgF
HXV88_18845	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HXV88_18850	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HXV88_18860	ENOG4105M8F	Biopolymer transport protein exbD tolR
HXV88_18865	ENOG4105E02	MotA TolQ exbB proton channel
HXV88_18870	ENOG4107YD3	Thioesterase
HXV88_18875	ENOG4105KJB	cyd operon protein YbgE
HXV88_18885	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HXV88_18890	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HXV88_18895	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HXV88_18900	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HXV88_18905	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_18910	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HXV88_18920	ENOG4105NNS	Autoinducer synthesis protein
HXV88_18925	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HXV88_18930	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HXV88_18945	ENOG4107VXZ	Hydrolase
HXV88_18950	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HXV88_18955	ENOG4105F1S	paraquat-inducible protein a
HXV88_18960	ENOG4105DY2	Paraquat-inducible protein b
HXV88_18965	ENOG4108Q2G	(LipO)protein
HXV88_18970	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HXV88_18975	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HXV88_18980	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
HXV88_18995	ENOG4105E39	Enoyl-CoA hydratase
HXV88_19000	ENOG4106WH9	Protein of unknown function (DUF2753)
HXV88_19005	ENOG4105EQK	-acetyltransferase
HXV88_19015	ENOG4107QSI	ABC, transporter
HXV88_19025	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HXV88_19050	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HXV88_19055	ENOG4108UV7	flagellar protein motX
HXV88_19060	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HXV88_19065	ENOG4105DMR	ABC, transporter
HXV88_19070	ENOG4105GBT	ABC transporter
HXV88_19075	ENOG4106TNF	Periplasmic binding protein
HXV88_19080	ENOG4105E5Z	arginine transporter ATP-binding subunit
HXV88_19085	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HXV88_19090	ENOG4105EZR	dyp-type peroxidase family protein
HXV88_19095	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HXV88_19110	ENOG4108YZA	Nitrogen regulatory protein pii
HXV88_19115	ENOG4108YZN	class I peptide chain release factor
HXV88_19130	ENOG4105D1Q	UPF0246 protein
HXV88_19135	ENOG4105CZX	twitching motility protein
HXV88_19140	ENOG4105CZX	twitching motility protein
HXV88_19145	ENOG4105DFA	alanine racemase domain protein
HXV88_19150	ENOG4105II7	pyrroline-5-carboxylate reductase
HXV88_19155	ENOG4108VIA	integral membrane protein
HXV88_19160	ENOG4105VZ9	UPF0235 protein
HXV88_19170	ENOG4105D9N	nucleoside
HXV88_19175	ENOG4105HEI	LysR family (Transcriptional regulator
HXV88_19195	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HXV88_19200	ENOG4105MYN	Zinc uptake regulation protein
HXV88_19215	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HXV88_19220	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HXV88_19225	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HXV88_19230	ENOG4105C1J	atp-dependent rna helicase
HXV88_19235	ENOG4107YB6	acetyltransferase, (GNAT) family
HXV88_19245	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HXV88_19250	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HXV88_19255	ENOG4106TD9	Diguanylate cyclase
HXV88_19260	ENOG4105UYK	outer membrane protein a
HXV88_19270	ENOG4105H4F	exported protein
HXV88_19280	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HXV88_19285	ENOG4105CEN	a g-specific adenine glycosylase
HXV88_19290	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HXV88_19310	ENOG4105BZW	Glycerate kinase
HXV88_19315	ENOG4107QQ0	gntp family
HXV88_19320	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HXV88_19325	ENOG4105XTV	UPF0231 protein
HXV88_19345	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
HXV88_19355	ENOG4105C1J	atp-dependent rna helicase
HXV88_19365	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HXV88_19395	ENOG4105CGF	Aromatic amino acid aminotransferase
HXV88_19410	ENOG41076CZ	activating enzyme
HXV88_19415	ENOG4105G0K	glycine radical enzyme YjjI family
HXV88_19440	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HXV88_19455	ENOG4105CND	Glycosyl transferase, family 2
HXV88_19460	ENOG4107BJW	polysaccharide deacetylase
HXV88_19475	ENOG4108N3W	hemolysin secretion protein
HXV88_19480	ENOG4108M1A	Chitin-binding protein
HXV88_19485	ENOG4107PU6	Membrane
HXV88_19490	ENOG4108UW5	maltose o-acetyltransferase
HXV88_19505	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HXV88_19510	ENOG4107RK2	ADP-ribose diphosphatase NudE
HXV88_19515	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HXV88_19525	ENOG4105C44	Serine transporter
HXV88_19530	ENOG4108Z7R	Chaperone CsaA
HXV88_19540	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HXV88_19545	ENOG4105C28	cystathionine
HXV88_19550	ENOG4105CFH	Aspartokinase
HXV88_19555	ENOG4105CJ3	phosphate transporter
HXV88_19560	ENOG4107IX6	phosphate transport regulator
HXV88_19570	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HXV88_19575	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HXV88_19580	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HXV88_19585	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HXV88_19625	ENOG4105DFD	Na H antiporter
HXV88_19630	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HXV88_19640	ENOG4105CMQ	Chloride channel
HXV88_19645	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HXV88_19660	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HXV88_19680	ENOG4107UNZ	domain protein
HXV88_19735	ENOG4108YGG	dna repair protein
HXV88_19770	ENOG410679B	prophage CP4-57 regulatory protein alpA
HXV88_19785	ENOG4108WC9	type VI secretion system effector, hcp1 family
HXV88_19795	ENOG4105CS6	Rhs element vgr protein
HXV88_19830	ENOG4105DFP	Integrase
HXV88_19860	ENOG4108JCI	Transcriptional regulator
HXV88_19865	ENOG4105DKK	Benzoate
HXV88_19875	ENOG4105SYT	Methylenetetrahydrofolate reductase
HXV88_19890	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_19895	ENOG4105EIF	outer membrane protein W
HXV88_19900	ENOG4105BZU	Histidine kinase
HXV88_19905	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HXV88_19925	ENOG4105P8Q	Curli production assembly transport component CsgG
HXV88_19935	ENOG4108XDW	curli assembly protein CsgE
HXV88_19940	ENOG41086KC	Transcriptional regulator
HXV88_19945	ENOG4108UUM	single-stranded DNA-binding protein
HXV88_19965	ENOG4105VEQ	Cold shock protein
HXV88_19970	ENOG4105C7N	Xanthine uracil vitamin C permease
HXV88_19975	ENOG4105CMT	Dihydroxyacetone kinase
HXV88_19980	ENOG4108UTZ	Dihydroxyacetone kinase
HXV88_19985	ENOG4105VDH	Dihydroxyacetone kinase
HXV88_19995	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HXV88_20005	ENOG4105IPI	Membrane
HXV88_20020	ENOG4105VEJ	Heat shock protein
HXV88_20025	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HXV88_20030	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HXV88_20045	ENOG4105VXR	cytoplasmic protein
HXV88_20050	ENOG4108R6G	acetyltransferase
HXV88_20055	ENOG4108XTF	Outer Membrane Lipoprotein
HXV88_20060	ENOG4105BZU	Histidine kinase
HXV88_20065	ENOG4106TD9	Diguanylate cyclase
HXV88_20075	ENOG4108TPP	exopolysaccharide synthesis
HXV88_20080	ENOG4105C44	Serine transporter
HXV88_20085	ENOG4105BZU	Histidine kinase
HXV88_20095	ENOG4105EQK	-acetyltransferase
HXV88_20125	ENOG4105D41	biosynthesis protein thiH
HXV88_20130	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HXV88_20140	ENOG4105D06	uba thif-type nad fad binding protein
HXV88_20145	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HXV88_20150	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HXV88_20170	ENOG4105ETX	regulatoR
HXV88_20180	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HXV88_20190	ENOG4105C3R	Methionine synthase
HXV88_20195	ENOG4105EEQ	Na H antiporter
HXV88_20230	ENOG4105CSH	Transporter
HXV88_20245	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HXV88_20260	ENOG4105QD6	exported protein
HXV88_20265	ENOG4105C03	ribonuclease
HXV88_20270	ENOG4108Z03	MAF-like protein
HXV88_20275	ENOG4105VQ7	Rod shape-determining protein MreD
HXV88_20280	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HXV88_20330	ENOG4105D7Q	type ii secretion system
HXV88_20335	ENOG4107QHF	type ii secretion system protein e
HXV88_20350	ENOG4105GVR	general secretion pathway protein D
HXV88_20380	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HXV88_20385	ENOG4105CXC	rtn protein
HXV88_20390	ENOG4105EWV	Sodium calcium exchanger membrane region
HXV88_20395	ENOG4105C84	Histidine ammonia-lyase
HXV88_20400	ENOG4105CGP	Urocanate hydratase
HXV88_20405	ENOG41088SP	formiminoglutamate hydrolase
HXV88_20410	ENOG4105CI2	imidazolone-5-propionate hydrolase
HXV88_20415	ENOG4105CZE	histidine utilization repressor
HXV88_20420	ENOG41077A9	carbonic anhydrase
HXV88_20430	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HXV88_20435	ENOG4105CAK	Cell division ATP-binding protein ftsE
HXV88_20440	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HXV88_20445	ENOG4106H78	methyltransferase
HXV88_20470	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HXV88_20475	ENOG4108W5M	transcriptional regulator
HXV88_20480	ENOG4105EMU	Dehydrogenase
HXV88_20495	ENOG4105CUG	Oligopeptidase b
HXV88_20510	ENOG4107RZC	phospholipase d
HXV88_20520	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HXV88_20540	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HXV88_20545	ENOG4105VVZ	metal-binding protein
HXV88_20560	ENOG4105JQN	Transcriptional regulator
HXV88_20575	ENOG4107FS9	Membrane
HXV88_20590	ENOG4105EJ2	Transcriptional regulator
HXV88_20630	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HXV88_20635	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HXV88_20640	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HXV88_20645	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HXV88_20650	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HXV88_20655	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HXV88_20660	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HXV88_20665	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HXV88_20670	ENOG4105KME	endoribonuclease L-psp
HXV88_20675	ENOG4105WWK	YheO domain protein
HXV88_20680	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HXV88_20685	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HXV88_20690	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HXV88_20695	ENOG4108VZM	50s ribosomal protein L10
HXV88_20700	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HXV88_20705	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HXV88_20710	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HXV88_20715	ENOG4105PM1	preprotein translocase subunit SecE
HXV88_20725	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HXV88_20745	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HXV88_20750	ENOG4105D4A	Cell wall formation (By similarity)
HXV88_20755	ENOG4107ZYR	domain protein
HXV88_20780	ENOG4108IYH	Dna topoisomerase
HXV88_20790	ENOG4105BZU	Histidine kinase
HXV88_20795	ENOG4105CUW	cytochrome C-TYPE protein
HXV88_20800	ENOG4107QY8	reductase
HXV88_20810	ENOG4105IFJ	Histidine kinase
HXV88_20815	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HXV88_20840	ENOG4108UQ5	membrane protein YcdZ
HXV88_20845	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HXV88_20855	ENOG4107WP9	Histidine kinase
HXV88_20870	ENOG410642E	Short chain dehydrogenase
HXV88_20875	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HXV88_20890	ENOG4108VVK	transcriptional Regulator, AsnC
HXV88_20895	ENOG4105CU9	asparagine synthetase A
HXV88_20900	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HXV88_20905	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HXV88_20910	ENOG4105C34	Pseudouridine synthase
HXV88_20915	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HXV88_20920	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
HXV88_20930	ENOG4105CEM	UPF0597 protein
HXV88_20935	ENOG4105WWK	YheO domain protein
HXV88_20945	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HXV88_20950	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HXV88_20955	ENOG4108I6A	alcohol dehydrogenase
HXV88_20960	ENOG4105CF7	AraC family transcriptional regulator
HXV88_20965	ENOG4105QNF	Outer membrane lipoprotein
HXV88_20970	ENOG4105C8Q	Methyl-accepting chemotaxis
HXV88_20980	ENOG4105DUM	transcriptional regulator, lysR family
HXV88_21000	ENOG4105CXT	aspartate transcarbamylase
HXV88_21005	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HXV88_21010	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HXV88_21015	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HXV88_21020	ENOG4105DBV	ornithine carbamoyltransferase
HXV88_21025	ENOG4105C5B	carbamate kinase
HXV88_21050	ENOG4105D4P	Coproporphyrinogen iii oxidase
HXV88_21055	ENOG4105XCT	Protein of unknown function (DUF2489)
HXV88_21060	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HXV88_21065	ENOG4106RE7	Cytochrome
HXV88_21070	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HXV88_21080	ENOG4105E2X	shikimate dehydrogenase
HXV88_21085	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HXV88_21090	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HXV88_21100	ENOG4108WI1	Dna topoisomerase
HXV88_21105	ENOG4108RPN	Protein smg homolog
HXV88_21110	ENOG4105C79	DNA protecting protein DprA
HXV88_21115	ENOG4108WZM	domain protein
HXV88_21120	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HXV88_21125	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HXV88_21130	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HXV88_21135	ENOG4105C1A	potassium transporter peripheral membrane
HXV88_21140	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HXV88_21145	ENOG4105CI3	gtp-binding protein typa
HXV88_21150	ENOG4105C5F	glutamine synthetase
HXV88_21160	ENOG4105CUX	Signal transduction histidine kinase
HXV88_21165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HXV88_21170	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HXV88_21175	ENOG4105CGY	Dna recombination protein
HXV88_21195	ENOG4108TFM	Kinase, PfkB family
HXV88_21200	ENOG4107R11	Transcriptional regulator
HXV88_21205	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HXV88_21210	ENOG4105C26	Dehydrogenase
HXV88_21220	ENOG4108JCI	Transcriptional regulator
HXV88_21225	ENOG4105C26	Dehydrogenase
HXV88_21235	ENOG4105FR1	rard protein
HXV88_21240	ENOG4108N3W	hemolysin secretion protein
HXV88_21245	ENOG4105CUC	YeeE YedE family protein
HXV88_21250	ENOG4105UYK	outer membrane protein a
HXV88_21255	ENOG4105C7B	Threonine dehydratase
HXV88_21260	ENOG4105C01	Dihydroxy-acid dehydratase
HXV88_21265	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HXV88_21270	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HXV88_21280	ENOG4105C0P	Mg chelatase subunit ChlI
HXV88_21285	ENOG4106HNH	Acyl-transferase
HXV88_21290	ENOG4106HNH	Acyl-transferase
HXV88_21295	ENOG4105EWC	Purine nucleoside phosphorylase
HXV88_21305	ENOG4108RWI	nicotinamidase
HXV88_21310	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HXV88_21315	ENOG4108Z33	Thiol disulfide Interchange Protein
HXV88_21320	ENOG4105E27	serine threonine protein kinase
HXV88_21330	ENOG4105PC1	Conserved Protein
HXV88_21340	ENOG4108Z6Z	Transcriptional regulator
HXV88_21350	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HXV88_21355	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HXV88_21360	ENOG4105DSJ	YicC domain protein
HXV88_21365	ENOG4105CC0	LysR family Transcriptional regulator
HXV88_21380	ENOG4105CR8	Transcriptional regulator
HXV88_21425	ENOG4105DHU	Bile acid
HXV88_21430	ENOG4105E5D	amino acid
HXV88_21435	ENOG4108Y51	tRNA-binding protein
HXV88_21440	ENOG4105E5D	amino acid
HXV88_21445	ENOG4105FK9	beta-D-galactosidase beta subunit
HXV88_21450	ENOG4105CNT	hydrolase family 2
HXV88_21455	ENOG4105CQ4	Transcriptional regulator
HXV88_21490	ENOG4108Z0R	Transferase
HXV88_21495	ENOG4105C2M	dna polymerase I
HXV88_21500	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HXV88_21505	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HXV88_21515	ENOG4105D7W	serine acetyltransferase
HXV88_21525	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HXV88_21530	ENOG4105E0F	Histidine kinase
HXV88_21535	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HXV88_21540	ENOG4107R73	Mate efflux family protein
HXV88_21555	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HXV88_21560	ENOG4105E55	glycerol-3-phosphate acyltransferase
HXV88_21565	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HXV88_21570	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HXV88_21590	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HXV88_21595	ENOG4105DIQ	Transcriptional regulator
HXV88_21600	ENOG4106ETB	IIa component
HXV88_21615	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HXV88_21620	ENOG4105XA0	heptosyltransferase ii
HXV88_21625	ENOG4106WTF	Glycosyl transferase, family 2
HXV88_21630	ENOG4105M5K	heptosyltransferase
HXV88_21635	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HXV88_21640	ENOG4108MJ5	VirK protein
HXV88_21645	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HXV88_21655	ENOG4105W0E	50S ribosomal protein L33
HXV88_21660	ENOG4105KDC	50s ribosomal protein l28
HXV88_21665	ENOG4105W5Q	DNA repair protein (RadC
HXV88_21670	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HXV88_21680	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HXV88_21700	ENOG4105VEQ	Cold shock protein
HXV88_21755	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HXV88_21765	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HXV88_21770	ENOG4105D64	Mechanosensitive ion channel
HXV88_21775	ENOG4107QP8	phosphohexose isomerase
HXV88_21780	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HXV88_21785	ENOG4105EMY	transcriptional regulator
HXV88_21800	ENOG4105CD5	CoA-binding domain protein
HXV88_21830	ENOG4108RR8	protoporphyrinogen oxidase
HXV88_21835	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HXV88_21840	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HXV88_21845	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
HXV88_21850	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HXV88_21855	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HXV88_21860	ENOG4105CHU	acetyl-coa acetyltransferase
HXV88_21870	ENOG4105E0F	Histidine kinase
HXV88_21885	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HXV88_21890	ENOG4105M4H	endoribonuclease L-psp
HXV88_21895	ENOG4108ZG0	Ompa motb domain protein
HXV88_21900	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HXV88_21905	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HXV88_21910	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HXV88_21925	ENOG4105BZU	Histidine kinase
HXV88_21930	ENOG41072JS	exoenzyme T
HXV88_21935	ENOG41072JS	exoenzyme T
HXV88_21950	ENOG4108NVR	Methyl-accepting chemotaxis
HXV88_21955	ENOG4105FDP	GntR family transcriptional regulator
HXV88_21960	ENOG4105CI1	PTS System
HXV88_21965	ENOG4105F8D	glycoside hydrolase family 4
HXV88_21970	ENOG4105ETE	Transcriptional regulator (LacI family
HXV88_21975	ENOG4105CP9	extracellular ligand-binding receptor
HXV88_21980	ENOG4105C32	Amino acid ABC transporter (Permease)
HXV88_21985	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HXV88_21990	ENOG4105C0Z	ABC transporter
HXV88_21995	ENOG4108IV0	ABC, transporter
HXV88_22000	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HXV88_22010	ENOG4105W0Z	cytoplasmic protein
HXV88_22020	ENOG4107QK7	reductase
HXV88_22025	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HXV88_22035	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HXV88_22045	ENOG4105C1J	atp-dependent rna helicase
HXV88_22050	ENOG4105C9X	ppx gppa phosphatase
HXV88_22060	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HXV88_22070	ENOG4105BZU	Histidine kinase
HXV88_22075	ENOG4105DGW	oligopeptidase A
HXV88_22080	ENOG4105E03	chitinase
HXV88_22085	ENOG4108M1A	Chitin-binding protein
HXV88_22090	ENOG4105D52	delta-aminolevulinic acid dehydratase
HXV88_22095	ENOG4105F8V	Hydrolase, tatD family
HXV88_22100	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HXV88_22105	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HXV88_22110	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HXV88_22115	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HXV88_22120	ENOG4105JC1	sterol-binding domain protein
HXV88_22125	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HXV88_22130	ENOG4105WMR	Protein CrcB homolog
HXV88_22135	ENOG4105DZC	cytosine deaminase
HXV88_22140	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HXV88_22185	ENOG410822N	TonB family
HXV88_22190	ENOG4109015	Biopolymer transport protein exbD tolR
HXV88_22210	ENOG4105VJY	transcriptional regulator
HXV88_22215	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HXV88_22220	ENOG410804X	Transcriptional regulator
HXV88_22225	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HXV88_22230	ENOG4105EB3	Histidine kinase
HXV88_22245	ENOG4105CT7	inner membrane cred family protein
HXV88_22260	ENOG4107RA4	Glycosyl transferase (Group 1
HXV88_22290	ENOG4105D75	Capsular exopolysaccharide family
HXV88_22305	ENOG4105D3Q	Sugar transferase
HXV88_22310	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HXV88_22315	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HXV88_22320	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HXV88_22325	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HXV88_22330	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HXV88_22335	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HXV88_22340	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HXV88_22345	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HXV88_22350	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HXV88_22360	ENOG4105FA0	parb-like partition protein
HXV88_22365	ENOG4107QJE	Chromosome Partitioning Protein
HXV88_22370	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HXV88_22375	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HXV88_22380	ENOG4105QTB	Flavodoxin
HXV88_22390	ENOG4105IBP	Cyclic peptide transporter
HXV88_22395	ENOG4105E0A	ABC, transporter
HXV88_22400	ENOG4105J76	Periplasmic binding protein
HXV88_22405	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HXV88_22410	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HXV88_22415	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HXV88_22420	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HXV88_22425	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HXV88_22430	ENOG4105VG0	50S ribosomal protein l34
HXV88_22435	ENOG4105CDA	abc transporter atp-binding protein
HXV88_22440	ENOG4105E5Q	amino acid AbC transporter
HXV88_22445	ENOG4105EAB	amino acid AbC transporter