locus-tag	class	description
EFI48_00005	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
EFI48_00010	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
EFI48_00015	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
EFI48_00020	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
EFI48_00025	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
EFI48_00030	ENOG4105D3Q	Sugar transferase
EFI48_00045	ENOG4105D75	Capsular exopolysaccharide family
EFI48_00075	ENOG4107RA4	Glycosyl transferase (Group 1
EFI48_00090	ENOG4105CT7	inner membrane cred family protein
EFI48_00105	ENOG4105EB3	Histidine kinase
EFI48_00110	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EFI48_00115	ENOG410804X	Transcriptional regulator
EFI48_00120	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
EFI48_00125	ENOG4105VJY	transcriptional regulator
EFI48_00145	ENOG4109015	Biopolymer transport protein exbD tolR
EFI48_00150	ENOG410822N	TonB family
EFI48_00185	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
EFI48_00190	ENOG4105DZC	cytosine deaminase
EFI48_00195	ENOG4105WMR	Protein CrcB homolog
EFI48_00200	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
EFI48_00205	ENOG4105JC1	sterol-binding domain protein
EFI48_00210	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
EFI48_00215	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
EFI48_00220	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
EFI48_00225	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
EFI48_00230	ENOG4105F8V	Hydrolase, tatD family
EFI48_00235	ENOG4105D52	delta-aminolevulinic acid dehydratase
EFI48_00240	ENOG4108M1A	Chitin-binding protein
EFI48_00245	ENOG4105E03	chitinase
EFI48_00250	ENOG4105DGW	oligopeptidase A
EFI48_00255	ENOG4105BZU	Histidine kinase
EFI48_00260	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
EFI48_00270	ENOG4105C9X	ppx gppa phosphatase
EFI48_00275	ENOG4105C1J	atp-dependent rna helicase
EFI48_00280	ENOG4105K63	Thioredoxin
EFI48_00285	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
EFI48_00295	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
EFI48_00300	ENOG4107QK7	reductase
EFI48_00305	ENOG4105BZU	Histidine kinase
EFI48_00310	ENOG4105W0Z	cytoplasmic protein
EFI48_00325	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
EFI48_00330	ENOG4108IV0	ABC, transporter
EFI48_00335	ENOG4105C0Z	ABC transporter
EFI48_00340	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
EFI48_00345	ENOG4105C32	Amino acid ABC transporter (Permease)
EFI48_00350	ENOG4105CP9	extracellular ligand-binding receptor
EFI48_00355	ENOG4105ETE	Transcriptional regulator (LacI family
EFI48_00360	ENOG4105F8D	glycoside hydrolase family 4
EFI48_00365	ENOG4105CI1	PTS System
EFI48_00370	ENOG4105FDP	GntR family transcriptional regulator
EFI48_00375	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_00395	ENOG41072JS	exoenzyme T
EFI48_00400	ENOG4105BZU	Histidine kinase
EFI48_00410	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
EFI48_00415	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
EFI48_00420	ENOG4108R3E	Dna-3-methyladenine glycosylase i
EFI48_00425	ENOG4108ZG0	Ompa motb domain protein
EFI48_00430	ENOG4105M4H	endoribonuclease L-psp
EFI48_00435	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
EFI48_00450	ENOG4105E0F	Histidine kinase
EFI48_00455	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EFI48_00460	ENOG4105CHU	acetyl-coa acetyltransferase
EFI48_00465	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EFI48_00470	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EFI48_00475	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
EFI48_00480	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
EFI48_00485	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EFI48_00490	ENOG4108RR8	protoporphyrinogen oxidase
EFI48_00525	ENOG4105CUZ	uba thif-type nad fad binding protein
EFI48_00530	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
EFI48_00535	ENOG4105C9B	Cysteine desulfurase
EFI48_00540	ENOG4105C4R	Atp-dependent dna helicase
EFI48_00545	ENOG4105BZU	Histidine kinase
EFI48_00550	ENOG4105MPD	Cytochrome
EFI48_00555	ENOG4105CPQ	Dehydrogenase
EFI48_00560	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EFI48_00565	ENOG41062JF	Transcriptional regulator
EFI48_00570	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
EFI48_00645	ENOG41061EV	selenium-binding protein YdfZ
EFI48_00655	ENOG4108UK5	Transposase
EFI48_00660	ENOG4105C4R	Atp-dependent dna helicase
EFI48_00665	ENOG4105DIH	basic membrane
EFI48_00670	ENOG4108JQ9	ABC transporter
EFI48_00675	ENOG4105UIB	(ABC) transporter
EFI48_00690	ENOG4105CGH	5'-nucleotidase
EFI48_00700	ENOG4105CJW	magnesium transporter
EFI48_00705	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EFI48_00710	ENOG4107V9H	nitrite transporter
EFI48_00715	ENOG4105WZK	nitrite reductase NADPH small subunit
EFI48_00720	ENOG4107QZF	nitrite reductase NADPH large subunit
EFI48_00725	ENOG4107QWP	ABC-2 type transporter
EFI48_00730	ENOG4107QWP	ABC-2 type transporter
EFI48_00735	ENOG4105CJ1	ABC, transporter
EFI48_00740	ENOG4105D0S	secretion protein (HlyD
EFI48_00750	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
EFI48_00755	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
EFI48_00765	ENOG4105C75	arginyL-tRNA synthetase
EFI48_00775	ENOG4105K6V	RNA polymerase
EFI48_00785	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
EFI48_00790	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
EFI48_00795	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EFI48_00800	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
EFI48_00805	ENOG4105CMR	udp-glucose 4-epimerase
EFI48_00810	ENOG41060NJ	transcriptional regulator
EFI48_00815	ENOG4105CNT	hydrolase family 2
EFI48_00825	ENOG4105C2J	ABC transporter
EFI48_00830	ENOG4108HWV	)-transporter
EFI48_00835	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_00840	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
EFI48_00855	ENOG4107R28	alpha amylase, catalytic region
EFI48_00870	ENOG4105R8A	Heat shock protein
EFI48_00875	ENOG4105C5I	Dehydrogenase
EFI48_00880	ENOG4108RH0	Crea protein
EFI48_00895	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EFI48_00900	ENOG4105CFQ	glutamine synthetase
EFI48_00905	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EFI48_00915	ENOG4108HM4	ABC transporter
EFI48_00920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EFI48_00925	ENOG4105F38	ABC transporter, permease
EFI48_00930	ENOG4105D38	putrescine abc transporter
EFI48_00935	ENOG4108RPX	mosc domain containing protein
EFI48_00950	ENOG4108VUY	thioesterase Superfamily protein
EFI48_00955	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EFI48_00960	ENOG4105N7H	Cytochrome
EFI48_00965	ENOG4105CNG	UPF0061 protein
EFI48_00975	ENOG4105EX9	Membrane
EFI48_00980	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EFI48_00985	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_01000	ENOG4105VFB	Binds the 23S rRNA (By similarity)
EFI48_01005	ENOG4105C25	Primosomal protein n'
EFI48_01015	ENOG4105CGD	Nad-dependent epimerase dehydratase
EFI48_01020	ENOG4105CIC	tryptophan-specific transport protein
EFI48_01025	ENOG4105C6K	Malic enzyme
EFI48_01030	ENOG4107S2Z	UPF0761 membrane protein
EFI48_01035	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
EFI48_01045	ENOG4105SUU	thioesterase domain
EFI48_01055	ENOG4105CB5	ATP-dependent DNA helicase recG
EFI48_01060	ENOG4105JIM	Phosphatidylserine synthase
EFI48_01065	ENOG4105C6Z	Gluconate
EFI48_01070	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
EFI48_01075	ENOG4105C01	Dihydroxy-acid dehydratase
EFI48_01080	ENOG4108UHU	Aldolase
EFI48_01085	ENOG4105DIQ	Transcriptional regulator
EFI48_01095	ENOG41063SB	peptidase
EFI48_01100	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
EFI48_01105	ENOG4107YZP	Rhodanese domain protein
EFI48_01110	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
EFI48_01115	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
EFI48_01120	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
EFI48_01125	ENOG4105MJ2	Competence protein
EFI48_01130	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
EFI48_01150	ENOG4105BZM	domain protein
EFI48_01155	ENOG4108RRZ	Transcription elongation factor GreB
EFI48_01160	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EFI48_01165	ENOG4105E0F	Histidine kinase
EFI48_01175	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
EFI48_01180	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
EFI48_01185	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
EFI48_01190	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
EFI48_01195	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EFI48_01200	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
EFI48_01205	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
EFI48_01210	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
EFI48_01215	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
EFI48_01220	ENOG41083MP	50s ribosomal protein l29
EFI48_01225	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
EFI48_01230	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
EFI48_01235	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
EFI48_01240	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EFI48_01245	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
EFI48_01250	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
EFI48_01255	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
EFI48_01260	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
EFI48_01265	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
EFI48_01270	ENOG4105VPB	50S ribosomal protein L30
EFI48_01275	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
EFI48_01280	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
EFI48_01285	ENOG41067V7	50S ribosomal protein L36
EFI48_01290	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EFI48_01295	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
EFI48_01300	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
EFI48_01305	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EFI48_01310	ENOG4108ZT0	50S ribosomal protein l17
EFI48_01350	ENOG4105D05	Receptor
EFI48_01355	ENOG4105BZU	Histidine kinase
EFI48_01360	ENOG4105E0F	Histidine kinase
EFI48_01365	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
EFI48_01380	ENOG4105CWB	LysR family transcriptional Regulator
EFI48_01390	ENOG4105C2I	pirin domain protein
EFI48_01395	ENOG4108VBZ	doxx family
EFI48_01400	ENOG4105DSY	exodeoxyribonuclease V, gamma
EFI48_01405	ENOG4107QKA	exodeoxyribonuclease V beta
EFI48_01410	ENOG4107QYX	exodeoxyribonuclease v alpha
EFI48_01420	ENOG4105BZU	Histidine kinase
EFI48_01450	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
EFI48_01460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EFI48_01490	ENOG4108IQK	o-acetylhomoserine
EFI48_01500	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
EFI48_01505	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
EFI48_01525	ENOG4107IFA	Lipase (EC 3.1.1.3)
EFI48_01530	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EFI48_01535	ENOG4108UDW	Transcriptional regulator, luxr family
EFI48_01555	ENOG4105CH6	catalase
EFI48_01560	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
EFI48_01585	ENOG4105MYG	DNA polymerase iii, chi subunit
EFI48_01590	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EFI48_01595	ENOG4108M8S	permease YjgP YjgQ family protein
EFI48_01600	ENOG4108K5H	permease YjgP YjgQ family protein
EFI48_01615	ENOG4105DFP	Integrase
EFI48_01705	ENOG41061WM	D-Alanyl-D-Alanine
EFI48_01710	ENOG4107SC7	Inner membrane transporter yjeM
EFI48_01730	ENOG4105CBT	Fructose-1,6-bisphosphatase
EFI48_01745	ENOG4105ECF	c-methyltransferase
EFI48_01750	ENOG41076E6	Uroporphyrinogen-III Synthase
EFI48_01755	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
EFI48_01760	ENOG4107T0K	Adenylate cyclase
EFI48_01765	ENOG4106CJB	Phospholipase Carboxylesterase
EFI48_01770	ENOG4105XQ6	frataxin-like protein
EFI48_01780	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
EFI48_01785	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
EFI48_01795	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EFI48_01800	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
EFI48_01810	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
EFI48_01820	ENOG4108Z86	Glutamine amidotransferase
EFI48_01825	ENOG4105N42	UPF0307 protein
EFI48_01830	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
EFI48_01840	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
EFI48_01845	ENOG4105VFK	BolA family
EFI48_01855	ENOG4105E3I	toluene tolerance
EFI48_01860	ENOG4107PE3	Mammalian cell entry related domain protein
EFI48_01865	ENOG4105CY3	ABC transporter, permease
EFI48_01870	ENOG4105DHJ	ABC, transporter
EFI48_01875	ENOG4105C2X	Arabinose 5-phosphate isomerase
EFI48_01880	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
EFI48_01885	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
EFI48_01890	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
EFI48_01895	ENOG4108IUZ	ABC transporter
EFI48_01900	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EFI48_01905	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
EFI48_01910	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
EFI48_01915	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
EFI48_01920	ENOG41080Z8	PHOSPHOCARRIER protein
EFI48_01940	ENOG41069H0	dihydroorotase EC 3.5.2.3
EFI48_01970	ENOG4105C0H	protease
EFI48_01975	ENOG4105C0H	protease
EFI48_01985	ENOG4105D6Z	AFG1 family ATPase
EFI48_01990	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
EFI48_01995	ENOG4108UJD	30S ribosomal protein S9
EFI48_02000	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EFI48_02005	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
EFI48_02010	ENOG4105EIX	cytochrome c1
EFI48_02015	ENOG4107MKT	Stringent starvation protein a
EFI48_02020	ENOG4105KB2	stringent starvation protein b
EFI48_02030	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EFI48_02035	ENOG41082RQ	UPF0102 protein
EFI48_02040	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
EFI48_02045	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
EFI48_02055	ENOG4108V6E	Cell division protein mraZ
EFI48_02060	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
EFI48_02065	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EFI48_02070	ENOG4105CJN	penicillin-binding protein
EFI48_02075	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
EFI48_02080	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
EFI48_02085	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
EFI48_02090	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
EFI48_02095	ENOG4105CNI	cell division protein FtsW
EFI48_02100	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
EFI48_02105	ENOG4105DFU	Cell wall formation (By similarity)
EFI48_02110	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
EFI48_02115	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
EFI48_02120	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
EFI48_02125	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EFI48_02135	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
EFI48_02140	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EFI48_02145	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
EFI48_02150	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
EFI48_02160	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
EFI48_02165	ENOG4105D7Q	type ii secretion system
EFI48_02170	ENOG4107QHF	type ii secretion system protein e
EFI48_02185	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
EFI48_02200	ENOG41073TP	transcriptional regulator
EFI48_02205	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
EFI48_02210	ENOG4107QSN	dihydrolipoamide acetyltransferase
EFI48_02215	ENOG4107QN2	dihydrolipoyl dehydrogenase
EFI48_02220	ENOG4105BZU	Histidine kinase
EFI48_02225	ENOG41069D7	Methyl-accepting chemotaxis
EFI48_02230	ENOG4105D78	K07001 NTE family protein
EFI48_02235	ENOG4107QIJ	Aconitate hydratase 2
EFI48_02240	ENOG4105BZU	Histidine kinase
EFI48_02250	ENOG4105CKI	cobalamin synthesis protein
EFI48_02255	ENOG4108IJF	Heavy metal efflux pump, CzcA
EFI48_02270	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
EFI48_02280	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFI48_02285	ENOG4107ZVW	dihydroneopterin aldolase
EFI48_02290	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
EFI48_02315	ENOG4105DWD	nucleoside recognition domain protein
EFI48_02335	ENOG4105CH7	arginosuccinase
EFI48_02340	ENOG4105CDH	Citrulline--aspartate ligase
EFI48_02350	ENOG4105CAS	nag kinase
EFI48_02355	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
EFI48_02365	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
EFI48_02370	ENOG4105EQK	-acetyltransferase
EFI48_02380	ENOG4105BZU	Histidine kinase
EFI48_02385	ENOG4105C44	Serine transporter
EFI48_02390	ENOG4108TPP	exopolysaccharide synthesis
EFI48_02400	ENOG4106TD9	Diguanylate cyclase
EFI48_02405	ENOG4105BZU	Histidine kinase
EFI48_02410	ENOG4108XTF	Outer Membrane Lipoprotein
EFI48_02415	ENOG4108R6G	acetyltransferase
EFI48_02420	ENOG4105VXR	cytoplasmic protein
EFI48_02435	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
EFI48_02440	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
EFI48_02445	ENOG4105VEJ	Heat shock protein
EFI48_02460	ENOG4105IPI	Membrane
EFI48_02465	ENOG410600T	transposase
EFI48_02490	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EFI48_02500	ENOG4105VDH	Dihydroxyacetone kinase
EFI48_02505	ENOG4108UTZ	Dihydroxyacetone kinase
EFI48_02510	ENOG4105CMT	Dihydroxyacetone kinase
EFI48_02515	ENOG4105C7N	Xanthine uracil vitamin C permease
EFI48_02520	ENOG4105VEQ	Cold shock protein
EFI48_02530	ENOG41076HS	cation diffusion facilitator family transporter
EFI48_02550	ENOG4108IMY	Transcriptional regulator
EFI48_02595	ENOG4105C7H	Helicase, RecD TraA family
EFI48_02630	ENOG4108UUM	single-stranded DNA-binding protein
EFI48_02635	ENOG41086KC	Transcriptional regulator
EFI48_02640	ENOG4108XDW	curli assembly protein CsgE
EFI48_02650	ENOG4105P8Q	Curli production assembly transport component CsgG
EFI48_02670	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
EFI48_02675	ENOG4105BZU	Histidine kinase
EFI48_02680	ENOG4105EIF	outer membrane protein W
EFI48_02685	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_02700	ENOG4105SYT	Methylenetetrahydrofolate reductase
EFI48_02710	ENOG4105DKK	Benzoate
EFI48_02715	ENOG4108JCI	Transcriptional regulator
EFI48_02750	ENOG41090HJ	UPF0265 protein
EFI48_02760	ENOG410667J	hydrolase
EFI48_02770	ENOG4108I62	cina-like protein
EFI48_02780	ENOG4105CVG	Homoserine O-transsuccinylase
EFI48_02790	ENOG4108YXU	transcriptional regulator AsnC family
EFI48_02795	ENOG4105E0M	Sulfatase
EFI48_02830	ENOG4105EMU	Dehydrogenase
EFI48_02835	ENOG4105DZW	Dipeptidase
EFI48_02845	ENOG4108I6A	alcohol dehydrogenase
EFI48_02850	ENOG4108Z5K	methylglyoxal synthase
EFI48_02855	ENOG4108UQY	Iron-storage protein
EFI48_02870	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
EFI48_02875	ENOG410904N	short-chain dehydrogenase reductase
EFI48_02880	ENOG4107R88	Chemotaxis protein (CheV)
EFI48_02895	ENOG4107GZ4	SanA protein
EFI48_02900	ENOG4107MM9	BNR Asp-box repeat-containing protein
EFI48_02905	ENOG4105CEY	Amp-dependent synthetase and ligase
EFI48_02910	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
EFI48_02915	ENOG4108IPT	Naphthoate synthase
EFI48_02920	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
EFI48_02925	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
EFI48_02930	ENOG4105E4F	Isochorismate synthase
EFI48_02935	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
EFI48_02955	ENOG4105C1J	atp-dependent rna helicase
EFI48_02960	ENOG4105D9N	nucleoside
EFI48_02965	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
EFI48_02970	ENOG4108UPT	UPF0178 protein
EFI48_02990	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EFI48_03000	ENOG4105E61	Mannitol repressor protein
EFI48_03005	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
EFI48_03010	ENOG4105CTS	PTS system mannitol-specific
EFI48_03015	ENOG4105D1S	lipid A biosynthesis
EFI48_03020	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
EFI48_03025	ENOG4105DFG	type I secretion outer membrane protein
EFI48_03030	ENOG41087AY	ADP-Ribose pyrophosphatase
EFI48_03035	ENOG4108SX3	cytoplasmic protein
EFI48_03040	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
EFI48_03045	ENOG4105IPS	esterase
EFI48_03050	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EFI48_03055	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EFI48_03065	ENOG4105DUX	Transporter
EFI48_03085	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EFI48_03090	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
EFI48_03095	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EFI48_03100	ENOG4105C5Q	Transcriptional regulator
EFI48_03105	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EFI48_03125	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
EFI48_03130	ENOG41087YS	Phage shock protein A
EFI48_03145	ENOG41082IR	Excinuclease ABC C subunit domain protein
EFI48_03160	ENOG4108RG0	uracil-dna glycosylase
EFI48_03170	ENOG4105ETT	transcriptional Regulator, LysR family
EFI48_03175	ENOG4105FAV	ABC, transporter
EFI48_03180	ENOG4105FDK	ABC transporter
EFI48_03185	ENOG4105NXV	High-affinity zinc uptake system protein
EFI48_03205	ENOG4105DR5	peptidase
EFI48_03215	ENOG4105R2J	Conserved Protein
EFI48_03235	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EFI48_03240	ENOG4105CEN	a g-specific adenine glycosylase
EFI48_03245	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
EFI48_03255	ENOG4105H4F	exported protein
EFI48_03265	ENOG4105UYK	outer membrane protein a
EFI48_03270	ENOG4106TD9	Diguanylate cyclase
EFI48_03275	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
EFI48_03290	ENOG4105C2N	RNA methyltransferase TrmH family group 3
EFI48_03300	ENOG4107YB6	acetyltransferase, (GNAT) family
EFI48_03305	ENOG4105C1J	atp-dependent rna helicase
EFI48_03310	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
EFI48_03315	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
EFI48_03320	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
EFI48_03335	ENOG4105MYN	Zinc uptake regulation protein
EFI48_03340	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EFI48_03345	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EFI48_03355	ENOG4107QSI	ABC, transporter
EFI48_03365	ENOG4105EQK	-acetyltransferase
EFI48_03370	ENOG4106WH9	Protein of unknown function (DUF2753)
EFI48_03375	ENOG4105E39	Enoyl-CoA hydratase
EFI48_03390	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
EFI48_03395	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
EFI48_03400	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EFI48_03410	ENOG4105DY2	Paraquat-inducible protein b
EFI48_03415	ENOG4105F1S	paraquat-inducible protein a
EFI48_03420	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EFI48_03425	ENOG4107VXZ	Hydrolase
EFI48_03440	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
EFI48_03445	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
EFI48_03450	ENOG4105NNS	Autoinducer synthesis protein
EFI48_03455	ENOG4105VJY	transcriptional regulator
EFI48_03460	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
EFI48_03465	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_03470	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
EFI48_03475	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
EFI48_03480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EFI48_03485	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EFI48_03495	ENOG4105KJB	cyd operon protein YbgE
EFI48_03500	ENOG4107YD3	Thioesterase
EFI48_03505	ENOG4105E02	MotA TolQ exbB proton channel
EFI48_03510	ENOG4105M8F	Biopolymer transport protein exbD tolR
EFI48_03520	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
EFI48_03525	ENOG4105KCK	Peptidoglycan-associated lipoprotein
EFI48_03530	ENOG4105UFD	tol-pal system protein YbgF
EFI48_03600	ENOG4105C8J	)-transporter
EFI48_03610	ENOG4105C8J	)-transporter
EFI48_03625	ENOG4108K4B	hydrolase
EFI48_03640	ENOG4105EW9	transcriptional regulator AsnC family
EFI48_03665	ENOG4105E0X	reductase
EFI48_03670	ENOG410600T	transposase
EFI48_03680	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
EFI48_03685	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
EFI48_03695	ENOG4105DSB	aldose 1-epimerase
EFI48_03700	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
EFI48_03705	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_03710	ENOG4105G5H	Membrane
EFI48_03715	ENOG4107QX8	SPFH domain, Band 7 family protein
EFI48_03720	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EFI48_03725	ENOG4105C11	sulfate adenylyltransferase), subunit 2
EFI48_03730	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
EFI48_03740	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
EFI48_03755	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EFI48_03790	ENOG4108UUE	Transcriptional regulator
EFI48_03805	ENOG4105F0N	pyrophosphate phospho-hydrolase
EFI48_03810	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_03820	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
EFI48_03825	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
EFI48_03830	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
EFI48_03835	ENOG4105BZ4	penicillin-binding protein
EFI48_03840	ENOG4105CQ7	ATP-dependent helicase
EFI48_03850	ENOG4105PW4	Sugar fermentation stimulation protein homolog
EFI48_03855	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EFI48_03860	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
EFI48_03865	ENOG4105DJ0	Poly(A) Polymerase
EFI48_03870	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EFI48_03875	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
EFI48_03880	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
EFI48_03890	ENOG4108ETY	sodium dicarboxylate symporter
EFI48_03910	ENOG4105CIZ	coA-substrate-specific enzyme activase
EFI48_03915	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
EFI48_03920	ENOG4105E3A	(ABC) transporter
EFI48_03925	ENOG4105DA5	(ABC) transporter
EFI48_03930	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
EFI48_03935	ENOG410630P	Transcriptional regulator
EFI48_03940	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
EFI48_03945	ENOG4105DFU	Cell wall formation (By similarity)
EFI48_03950	ENOG41076MN	Phosphoesterase, PA-phosphatase related
EFI48_03955	ENOG4105CMR	udp-glucose 4-epimerase
EFI48_03960	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EFI48_03965	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
EFI48_03970	ENOG4108RMU	ferritin dps family protein
EFI48_03975	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
EFI48_03980	ENOG4108W15	Protein of unknown function (DUF1456)
EFI48_03985	ENOG4105BZU	Histidine kinase
EFI48_03990	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
EFI48_03995	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EFI48_04000	ENOG4105DXN	mazG family
EFI48_04005	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
EFI48_04010	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
EFI48_04055	ENOG4105D6S	protein involved in catabolism of external DNA
EFI48_04065	ENOG4105C5H	ABC transporter
EFI48_04085	ENOG4107SQD	Transcriptional regulator, GntR family
EFI48_04110	ENOG4105XEP	YhcH YjgK YiaL family protein
EFI48_04120	ENOG4105CUY	Mechanosensitive ion channel
EFI48_04125	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EFI48_04135	ENOG4105CK7	Sodium proline symporter
EFI48_04140	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
EFI48_04145	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
EFI48_04150	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
EFI48_04155	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
EFI48_04160	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
EFI48_04165	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
EFI48_04170	ENOG4108UM1	dedA family
EFI48_04185	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EFI48_04195	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
EFI48_04205	ENOG4105DWY	Agmatine deiminase
EFI48_04210	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
EFI48_04220	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
EFI48_04230	ENOG4105C1J	atp-dependent rna helicase
EFI48_04235	ENOG4105BZU	Histidine kinase
EFI48_04245	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
EFI48_04260	ENOG4107QWG	2-Nitropropane dioxygenase
EFI48_04325	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
EFI48_04335	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_04340	ENOG4105EYW	Ion transport protein
EFI48_04345	ENOG4106MWK	domain protein
EFI48_04350	ENOG4105C26	Dehydrogenase
EFI48_04355	ENOG4105E09	nadh pyrophosphatase
EFI48_04360	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
EFI48_04365	ENOG4105DKQ	ROK family
EFI48_04370	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
EFI48_04375	ENOG4105BZA	Phosphoglycerate kinase
EFI48_04380	ENOG4105D2N	Aldolase
EFI48_04385	ENOG4105CJP	fad dependent oxidoreductase
EFI48_04400	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
EFI48_04425	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
EFI48_04430	ENOG4105Y75	tpr repeat protein
EFI48_04440	ENOG4108IYU	L-aspartate oxidase
EFI48_04445	ENOG4105EMN	RNA polymerase sigma factor
EFI48_04450	ENOG41069PW	sigma-e factor negative regulatory protein
EFI48_04455	ENOG4105VQK	sigma E regulatory protein, MucB RseB
EFI48_04465	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
EFI48_04470	ENOG4105C3F	Signal peptidase i
EFI48_04475	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
EFI48_04485	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
EFI48_04490	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
EFI48_04495	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EFI48_04500	ENOG4105K9H	YciI-like protein
EFI48_04505	ENOG4107835	probably involved in intracellular septation (By similarity)
EFI48_04510	ENOG4105DY8	decarboxylase
EFI48_04515	ENOG4108UT2	hemolysin iii
EFI48_04520	ENOG4105D0C	transport protein
EFI48_04650	ENOG4105BZU	Histidine kinase
EFI48_04655	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
EFI48_04680	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
EFI48_04685	ENOG4105DD7	kinase (PfkB family
EFI48_04720	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
EFI48_04725	ENOG4108UKZ	OsmC family
EFI48_04740	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
EFI48_04745	ENOG4105YP7	UPF0270 protein
EFI48_04755	ENOG4105DNZ	Alpha Beta Hydrolase
EFI48_04760	ENOG4107R88	Chemotaxis protein (CheV)
EFI48_04770	ENOG4105VKU	nucleicacid-binding protein
EFI48_04775	ENOG4108YZY	peptidylprolyl cis-trans isomerase
EFI48_04790	ENOG4105CDU	Replicative dna helicase
EFI48_04795	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EFI48_04800	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
EFI48_04805	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
EFI48_04820	ENOG4105EHG	Permease protein
EFI48_04830	ENOG41090JE	Utilization Protein
EFI48_04835	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
EFI48_04865	ENOG4105D8G	Major Facilitator superfamily
EFI48_04875	ENOG4105VMP	Transcriptional regulator
EFI48_04885	ENOG4105BZU	Histidine kinase
EFI48_04895	ENOG4105BZU	Histidine kinase
EFI48_04905	ENOG4108MA4	Peptidase M66
EFI48_04910	ENOG4108M1A	Chitin-binding protein
EFI48_04955	ENOG4107R88	Chemotaxis protein (CheV)
EFI48_04960	ENOG4108UJV	acyl-CoA thioesterase i
EFI48_04965	ENOG4108I0Y	(ABC) transporter
EFI48_04970	ENOG4105CV6	ABC transporter, permease
EFI48_04975	ENOG4105ECP	epimerase
EFI48_04980	ENOG4105BZU	Histidine kinase
EFI48_04985	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EFI48_04990	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
EFI48_04995	ENOG41090ED	Protein with unknown function (DUF469)
EFI48_05000	ENOG4105CSV	Glutaminase
EFI48_05005	ENOG4107RM6	sulfurtransferase
EFI48_05010	ENOG4105SUV	lipoprotein YgdR
EFI48_05020	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EFI48_05030	ENOG4105DWK	Membrane
EFI48_05035	ENOG4107XM3	UPF0442 protein
EFI48_05045	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
EFI48_05050	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
EFI48_05055	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
EFI48_05060	ENOG4105JAB	phenazine biosynthesis protein, phzf family
EFI48_05065	ENOG4105CRK	lysyL-tRNA synthetase
EFI48_05075	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_05080	ENOG4105D6U	Sodium Glutamate Symporter
EFI48_05085	ENOG4105HDK	L-asparaginase
EFI48_05090	ENOG4105VUT	cytoplasmic protein
EFI48_05110	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
EFI48_05115	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
EFI48_05120	ENOG4108Z43	UPF0250 protein
EFI48_05125	ENOG4105DZ1	carboxypeptidase
EFI48_05130	ENOG4105K6T	rare lipoprotein A
EFI48_05135	ENOG4105CVE	Lytic murein transglycosylase
EFI48_05140	ENOG4105CNI	cell division protein FtsW
EFI48_05145	ENOG4105CJN	penicillin-binding protein
EFI48_05150	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
EFI48_05155	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
EFI48_05160	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
EFI48_05175	ENOG4105C8T	Leucyl-tRNA synthetase
EFI48_05180	ENOG4107PAI	alpha helical protein
EFI48_05195	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
EFI48_05200	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EFI48_05205	ENOG4105BZU	Histidine kinase
EFI48_05210	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
EFI48_05220	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
EFI48_05225	ENOG4107SWG	transcriptional regulator MERR family
EFI48_05230	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
EFI48_05235	ENOG4108JU5	Magnesium and cobalt efflux protein
EFI48_05240	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
EFI48_05245	ENOG4105C9A	Phoh family
EFI48_05250	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
EFI48_05255	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EFI48_05260	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
EFI48_05265	ENOG4105VEQ	Cold shock protein
EFI48_05270	ENOG4105BZU	Histidine kinase
EFI48_05275	ENOG4106KR7	LysR family Transcriptional regulator
EFI48_05305	ENOG4105C5I	Dehydrogenase
EFI48_05315	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
EFI48_05325	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EFI48_05335	ENOG4105DHQ	Histidine kinase
EFI48_05340	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EFI48_05350	ENOG4105EMU	Dehydrogenase
EFI48_05375	ENOG4105CJP	fad dependent oxidoreductase
EFI48_05390	ENOG4105T0Z	Conserved Protein
EFI48_05400	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EFI48_05405	ENOG4108P2H	Inner membrane protein YjiG
EFI48_05410	ENOG41074DU	domain protein
EFI48_05415	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
EFI48_05420	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
EFI48_05425	ENOG4105E33	succinate dehydrogenase
EFI48_05435	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_05440	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
EFI48_05445	ENOG4105EGS	Mechanosensitive ion channel
EFI48_05455	ENOG4105DR5	peptidase
EFI48_05465	ENOG4105EJC	lysr family transcriptional regulator
EFI48_05480	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_05485	ENOG4105C5Q	Transcriptional regulator
EFI48_05490	ENOG4108JQC	penicillin-binding protein 1A
EFI48_05515	ENOG4105E4G	Type IV pilus
EFI48_05520	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
EFI48_05525	ENOG4105D49	3-dehydroquinate synthase
EFI48_05535	ENOG4105DFE	Dna adenine methylase
EFI48_05540	ENOG4105DJV	ribulose-phosphate 3-epimerase
EFI48_05545	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EFI48_05550	ENOG4105C31	Tryptophanyl-tRNA synthetase
EFI48_05560	ENOG4105DDQ	anthranilate synthase
EFI48_05565	ENOG4105C8Y	Acetylornithine aminotransferase
EFI48_05575	ENOG4105C26	Dehydrogenase
EFI48_05590	ENOG4107VXZ	Hydrolase
EFI48_05600	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
EFI48_05605	ENOG4105CG3	alpha amylase, catalytic region
EFI48_05620	ENOG4105N5Z	UPF0267 protein
EFI48_05630	ENOG4108I5U	Uridine phosphorylase
EFI48_05635	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
EFI48_05640	ENOG4107QWE	)-transporter
EFI48_05715	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
EFI48_05720	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
EFI48_05725	ENOG4105CMR	udp-glucose 4-epimerase
EFI48_05730	ENOG41060NJ	transcriptional regulator
EFI48_05735	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
EFI48_05750	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_05760	ENOG4107FKK	extracellular solute-binding protein family 1
EFI48_05770	ENOG4105EG2	ABC transporter, permease
EFI48_05780	ENOG4105C4C	beta-galactosidase
EFI48_05785	ENOG4105CI1	PTS System
EFI48_05795	ENOG4105CA9	Pyruvate kinase
EFI48_05810	ENOG4105W5Q	DNA repair protein (RadC
EFI48_05855	ENOG4108NF7	phage-type endonuclease
EFI48_05865	ENOG4105C3G	gtp-binding protein
EFI48_05870	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
EFI48_05875	ENOG4105CGH	5'-nucleotidase
EFI48_05880	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
EFI48_05890	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
EFI48_05895	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
EFI48_05900	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
EFI48_05905	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
EFI48_05910	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
EFI48_05920	ENOG41063JG	Transcriptional regulator
EFI48_05925	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
EFI48_05930	ENOG4105CK2	sodium dicarboxylate symporter
EFI48_05935	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
EFI48_05945	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
EFI48_05955	ENOG4107WCA	isomerase
EFI48_05965	ENOG4108V1U	phospholipid-binding protein
EFI48_05970	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
EFI48_05985	ENOG4105C87	Aminotransferase class I and II
EFI48_05995	ENOG4105C5Q	Transcriptional regulator
EFI48_06000	ENOG4105UBK	short-chain dehydrogenase reductase
EFI48_06005	ENOG4105ERU	peptidase
EFI48_06010	ENOG4105E5W	Transporter
EFI48_06015	ENOG4105BZU	Histidine kinase
EFI48_06020	ENOG41090EX	DsrE family
EFI48_06030	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
EFI48_06035	ENOG4105CFP	Peptidase U32
EFI48_06040	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
EFI48_06060	ENOG41068CG	regulatoR
EFI48_06065	ENOG4105BZU	Histidine kinase
EFI48_06090	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
EFI48_06095	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
EFI48_06105	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EFI48_06110	ENOG4105E2D	ec 3.2.1.52
EFI48_06115	ENOG4105RD7	BadF BadG BcrA BcrD
EFI48_06125	ENOG4108JQ7	(ABC) transporter
EFI48_06135	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EFI48_06150	ENOG4105BZU	Histidine kinase
EFI48_06170	ENOG4105XIQ	Protein of unknown function (DUF2517)
EFI48_06200	ENOG4107SDU	Methyl-accepting chemotaxis
EFI48_06210	ENOG4108ESY	Metal dependent phosphohydrolase
EFI48_06215	ENOG4105DR8	Membrane
EFI48_06220	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EFI48_06225	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
EFI48_06230	ENOG4108IUZ	ABC transporter
EFI48_06235	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
EFI48_06245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EFI48_06250	ENOG4105BZU	Histidine kinase
EFI48_06260	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EFI48_06295	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EFI48_06295	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EFI48_06300	ENOG4105QAX	Iron-sulfur
EFI48_06320	ENOG4107R1I	NAD-dependent malic enzyme
EFI48_06335	ENOG4105C2W	permease
EFI48_06340	ENOG4106TNF	Periplasmic binding protein
EFI48_06345	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_06370	ENOG4105CHC	glucokinase (EC 2.7.1.2)
EFI48_06375	ENOG4106KNT	transcriptional regulator
EFI48_06380	ENOG4105CA9	Pyruvate kinase
EFI48_06400	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
EFI48_06405	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
EFI48_06410	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EFI48_06420	ENOG4108JIR	Flagellum-specific ATP synthase
EFI48_06440	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
EFI48_06445	ENOG4105DD5	Flagellar motor switch protein
EFI48_06450	ENOG4105VTB	flagellar biosynthesis protein fliO
EFI48_06455	ENOG4105CN7	Flagellar biosynthetic protein FliP
EFI48_06460	ENOG4105VS8	Flagellar biosynthetic protein fliq
EFI48_06465	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
EFI48_06470	ENOG4105D00	flagellar biosynthetic protein flhB
EFI48_06475	ENOG4105D7B	Flagellar biosynthesis protein flha
EFI48_06480	ENOG4105FZW	flagellar biosynthesis regulator FlhF
EFI48_06490	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EFI48_06495	ENOG4108VYJ	response regulator receiver protein
EFI48_06500	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
EFI48_06505	ENOG4105CBS	Chea signal transduction histidine kinase
EFI48_06515	ENOG4105E14	MotA TolQ exbB proton channel
EFI48_06520	ENOG4108SEK	ompa motb domain protein
EFI48_06525	ENOG4107QJE	Chromosome Partitioning Protein
EFI48_06535	ENOG4108V3W	Chemotaxis protein, CheW
EFI48_06550	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
EFI48_06555	ENOG41060IM	Heme exporter protein
EFI48_06560	ENOG4105X3C	heme exporter protein
EFI48_06565	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
EFI48_06570	ENOG4105DA4	cytochrome c-type biogenesis protein
EFI48_06575	ENOG4107QX9	Thiol disulfide interChange protein
EFI48_06580	ENOG4105KWW	Biogenesis protein
EFI48_06590	ENOG410903C	(LipO)protein
EFI48_06595	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
EFI48_06600	ENOG4105M2J	Glutaredoxin
EFI48_06605	ENOG4105C7B	Threonine dehydratase
EFI48_06610	ENOG4108MST	Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity)
EFI48_06615	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EFI48_06620	ENOG4105C6N	Formate acetyltransferase
EFI48_06625	ENOG4105KME	endoribonuclease L-psp
EFI48_06665	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
EFI48_06670	ENOG4108TGY	Glutathione S-transferase
EFI48_06690	ENOG4105EZE	Cupin 4 family protein
EFI48_06695	ENOG4107QTF	adenylosuccinate lyase
EFI48_06700	ENOG41075W9	High frequency lysogenization protein HflD homolog
EFI48_06705	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
EFI48_06715	ENOG4108R99	pseudouridine synthase
EFI48_06725	ENOG4108YRF	PTS System
EFI48_06730	ENOG4105CXY	transporter
EFI48_06735	ENOG4105DM4	PTS System
EFI48_06755	ENOG410600T	transposase
EFI48_06760	ENOG410600T	transposase
EFI48_06770	ENOG4105F38	ABC transporter, permease
EFI48_06780	ENOG4105EVZ	LysR family transcriptional regulator
EFI48_06785	ENOG4105C26	Dehydrogenase
EFI48_06790	ENOG4108JPW	Aminotransferase
EFI48_06800	ENOG4105CMU	LysR family (Transcriptional regulator
EFI48_06810	ENOG41067MG	lrgb family
EFI48_06815	ENOG4105D6F	Phosphatase
EFI48_06870	ENOG4107P2S	Transcriptional regulator
EFI48_06875	ENOG4105CI1	PTS System
EFI48_06880	ENOG4105C87	Aminotransferase class I and II
EFI48_06885	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
EFI48_06895	ENOG4105BZS	acriflavin resistance protein
EFI48_06900	ENOG4107QPN	acyl-Coa dehydrogenase
EFI48_06910	ENOG4107SSZ	Phosphatase
EFI48_06985	ENOG4105BZU	Histidine kinase
EFI48_06995	ENOG410620I	Diguanylate cyclase
EFI48_07005	ENOG4105BZU	Histidine kinase
EFI48_07010	ENOG4105WH1	Two component transcriptional regulator luxr family
EFI48_07015	ENOG4108JUA	Transcriptional regulator
EFI48_07020	ENOG4105CNW	domain protein
EFI48_07025	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
EFI48_07095	ENOG4108IEG	Formate dehydrogenase Alpha subunit
EFI48_07100	ENOG4105BZU	Histidine kinase
EFI48_07105	ENOG4105BZU	Histidine kinase
EFI48_07115	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
EFI48_07120	ENOG4108Z1B	Cyclase dehydrase
EFI48_07125	ENOG4105VDB	UPF0125 protein
EFI48_07130	ENOG4105CH2	amidohydrolase
EFI48_07135	ENOG4107QPN	acyl-Coa dehydrogenase
EFI48_07140	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
EFI48_07145	ENOG4105E7A	Glutamine amidotransferase
EFI48_07155	ENOG4105CHW	UPF0052 protein
EFI48_07165	ENOG4105BZU	Histidine kinase
EFI48_07175	ENOG4105WH1	Two component transcriptional regulator luxr family
EFI48_07180	ENOG4105BZU	Histidine kinase
EFI48_07185	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EFI48_07200	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
EFI48_07205	ENOG4108BGM	Quinol dehydrogenase periplasmic component
EFI48_07210	ENOG4105GXZ	Ferredoxin-type protein NapH
EFI48_07220	ENOG4105CUW	cytochrome C-TYPE protein
EFI48_07225	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
EFI48_07230	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
EFI48_07235	ENOG4105M00	molybdopterin converting factor, subunit 1
EFI48_07240	ENOG4108ZAF	Molybdopterin
EFI48_07245	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
EFI48_07250	ENOG4105E0C	molybdate abc transporter
EFI48_07255	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
EFI48_07260	ENOG410832A	alpha/beta hydrolase fold
EFI48_07265	ENOG4105D06	uba thif-type nad fad binding protein
EFI48_07270	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
EFI48_07275	ENOG4105EUJ	GTP cyclohydrolase i
EFI48_07280	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_07285	ENOG4105CKU	formyltetrahydrofolate synthetase
EFI48_07295	ENOG4105CC0	LysR family Transcriptional regulator
EFI48_07300	ENOG4108YYC	ycei family
EFI48_07310	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
EFI48_07325	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
EFI48_07335	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
EFI48_07345	ENOG4105EUZ	Beta-lactamase domain protein
EFI48_07365	ENOG4105C44	Serine transporter
EFI48_07370	ENOG4105KME	endoribonuclease L-psp
EFI48_07375	ENOG4105CEM	UPF0597 protein
EFI48_07380	ENOG4105WWK	YheO domain protein
EFI48_07395	ENOG4105M7P	phage repressor
EFI48_07515	ENOG4108Z6H	mu-like prophage Flumu protein gp27
EFI48_07520	ENOG4105CF2	Mu-like prophage FluMu protein GP28
EFI48_07525	ENOG4105QIB	mu-like prophage Flumu protein gp29
EFI48_07560	ENOG4108TVE	i protein
EFI48_07565	ENOG4105EFV	Major head subunit
EFI48_07645	ENOG4105RKW	reductase (By
EFI48_07650	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
EFI48_07655	ENOG4105CHM	Aminotransferase
EFI48_07665	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EFI48_07670	ENOG4105E4C	Lytic transglycosylase catalytic
EFI48_07685	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
EFI48_07695	ENOG4105CIY	formyltetrahydrofolate deformylase
EFI48_07700	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
EFI48_07710	ENOG4107QR8	Thioredoxin
EFI48_07715	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
EFI48_07720	ENOG4107TT5	NLP P60 protein
EFI48_07725	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
EFI48_07735	ENOG4105C8P	)-transporter
EFI48_07745	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EFI48_07760	ENOG4105VCP	PTS System
EFI48_07765	ENOG4105CS2	ec 3.2.1.21
EFI48_07775	ENOG4105VZJ	PTS System
EFI48_07780	ENOG4105E08	Glycoside hydrolase, family 9
EFI48_07795	ENOG4107FKK	extracellular solute-binding protein family 1
EFI48_07800	ENOG4105ETE	Transcriptional regulator (LacI family
EFI48_07820	ENOG4105BZS	acriflavin resistance protein
EFI48_07825	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EFI48_07830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EFI48_07835	ENOG4105BZU	Histidine kinase
EFI48_07845	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
EFI48_07860	ENOG4105E9H	Lytic Murein transglycosylase
EFI48_07865	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
EFI48_07870	ENOG4105D1A	Methyltransferase
EFI48_07875	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EFI48_07880	ENOG4107RZZ	dna polymerase iii epsilon subunit
EFI48_07890	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_07895	ENOG4105Q26	Siderophore-interacting protein
EFI48_07900	ENOG4105DQ5	transport system permease protein
EFI48_07905	ENOG4105TVJ	transport system, permease
EFI48_07910	ENOG4105E0A	ABC, transporter
EFI48_07915	ENOG4105S10	periplasmic binding protein
EFI48_07925	ENOG4108IJF	Heavy metal efflux pump, CzcA
EFI48_07930	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
EFI48_07940	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
EFI48_07965	ENOG4105CGK	Exodeoxyribonuclease III
EFI48_07995	ENOG4108YXG	UPF0502 protein
EFI48_08000	ENOG4105BZU	Histidine kinase
EFI48_08010	ENOG4105Z2P	Protein of unknown function (DUF465)
EFI48_08020	ENOG4105UQX	Mate efflux family protein
EFI48_08045	ENOG4105C0A	alcohol dehydrogenase
EFI48_08055	ENOG4107Z3H	Transcriptional regulator, TetR family
EFI48_08060	ENOG4107RGH	Aldehyde dehydrogenase
EFI48_08090	ENOG4105KAF	membrAne
EFI48_08105	ENOG4105DM4	PTS System
EFI48_08110	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_08115	ENOG4105EIP	mannose-6-phosphate isomerase
EFI48_08120	ENOG4106R3P	AraC family transcriptional regulator
EFI48_08125	ENOG4108HMX	isocitrate dehydrogenase (NADP)
EFI48_08135	ENOG4105BZC	d-serine deaminase
EFI48_08145	ENOG4105W8I	Transcriptional regulator
EFI48_08155	ENOG4108QBX	(LipO)protein
EFI48_08160	ENOG4105C5Q	Transcriptional regulator
EFI48_08165	ENOG4105D3R	alkyl hydroperoxide reductase
EFI48_08185	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
EFI48_08190	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
EFI48_08195	ENOG41081XQ	Conserved Protein
EFI48_08205	ENOG4105C9M	aspartyl-trna synthetase
EFI48_08210	ENOG4105CDY	transcriptional regulatory protein
EFI48_08220	ENOG4108EKI	Dehydrogenase
EFI48_08225	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
EFI48_08230	ENOG4107QSI	ABC, transporter
EFI48_08235	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EFI48_08240	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EFI48_08245	ENOG4105C3U	ABC transporter
EFI48_08250	ENOG4108JQ7	(ABC) transporter
EFI48_08255	ENOG4105DU1	integral membrane protein, terc
EFI48_08260	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
EFI48_08270	ENOG4105CZX	twitching motility protein
EFI48_08285	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
EFI48_08290	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
EFI48_08295	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EFI48_08300	ENOG41080IJ	Diacylglycerol kinase
EFI48_08305	ENOG4108JQ1	Dehydrogenase
EFI48_08310	ENOG4105E66	phosphoriboisomerase A
EFI48_08315	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
EFI48_08330	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
EFI48_08335	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
EFI48_08340	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
EFI48_08345	ENOG4107QS8	(LipO)protein
EFI48_08355	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EFI48_08365	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EFI48_08370	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EFI48_08405	ENOG4105K59	histidine triad (HIT) protein
EFI48_08410	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_08420	ENOG4105CD3	dihydroorotase
EFI48_08435	ENOG4105CK2	sodium dicarboxylate symporter
EFI48_08440	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_08450	ENOG4105CKW	Inner membrane protein yedI
EFI48_08455	ENOG4105DPN	Oligoendopeptidase f
EFI48_08460	ENOG4105C2W	permease
EFI48_08470	ENOG4105CEP	NADH dehydrogenase
EFI48_08480	ENOG4105F1A	Pyruvate formate-lyase
EFI48_08485	ENOG4105BZU	Histidine kinase
EFI48_08490	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
EFI48_08500	ENOG4105DN3	alpha-2-macroglobulin domain protein
EFI48_08505	ENOG4108JQB	penicillin-binding protein 1C
EFI48_08520	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
EFI48_08530	ENOG4105EN6	Membrane
EFI48_08535	ENOG4105I03	Flagellin
EFI48_08540	ENOG4105I03	Flagellin
EFI48_08545	ENOG4105I03	Flagellin
EFI48_08560	ENOG4105MQ3	flagellar protein FliS
EFI48_08595	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EFI48_08605	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EFI48_08610	ENOG4105C5E	polysaccharide biosynthesis protein
EFI48_08625	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
EFI48_08645	ENOG4105CYM	Glutathione S-transferase
EFI48_08650	ENOG4105E5M	Multidrug resistance protein D
EFI48_08655	ENOG4105EJC	lysr family transcriptional regulator
EFI48_08660	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EFI48_08665	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
EFI48_08675	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
EFI48_08685	ENOG4105D0A	hydroxylase
EFI48_08690	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
EFI48_08700	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
EFI48_08705	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
EFI48_08710	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EFI48_08795	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
EFI48_08815	ENOG4105C85	amino acid
EFI48_08825	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
EFI48_08830	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
EFI48_08845	ENOG4105D01	(LipO)protein
EFI48_08850	ENOG4105E68	Sulfatase
EFI48_08855	ENOG4105PAN	UPF0352 protein
EFI48_08860	ENOG4106V8H	Nucleoid-associated protein
EFI48_08865	ENOG4107FKK	extracellular solute-binding protein family 1
EFI48_08870	ENOG4105D56	permease protein
EFI48_08875	ENOG4105EG2	ABC transporter, permease
EFI48_08880	ENOG4108IJ9	(ABC) transporter
EFI48_08885	ENOG4105CSR	polyphosphate kinase 2
EFI48_08910	ENOG4105ERG	peptidase m48, ste24p
EFI48_08920	ENOG4105K89	arsenate reductase
EFI48_08930	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
EFI48_08935	ENOG4106PMH	Extracellular solute-binding protein family 3
EFI48_08940	ENOG4105DYB	Isoaspartyl dipeptidase
EFI48_08945	ENOG4105DWU	Membrane
EFI48_08950	ENOG4108JEH	abc transporter atp-binding protein
EFI48_08955	ENOG4106PMH	Extracellular solute-binding protein family 3
EFI48_08960	ENOG4105DSP	amino acid AbC transporter
EFI48_08965	ENOG4106YG3	ABC transporter
EFI48_08970	ENOG4108W1A	pseudouridine synthase
EFI48_08980	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
EFI48_08985	ENOG4105F1J	Homogentisate 1,2-dioxygenase
EFI48_08995	ENOG4108RXX	maleylacetoacetate isomerase
EFI48_09020	ENOG4105DHQ	Histidine kinase
EFI48_09025	ENOG4105Y3U	Transglycosylase-associated protein
EFI48_09035	ENOG4108UNC	
EFI48_09040	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
EFI48_09050	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EFI48_09060	ENOG4105C4R	Atp-dependent dna helicase
EFI48_09105	ENOG4108ZJT	translation initiation factor, Sui1
EFI48_09130	ENOG4105C1J	atp-dependent rna helicase
EFI48_09140	ENOG4105BZ8	glutamate synthase
EFI48_09145	ENOG4105CBC	glutamate synthase
EFI48_09150	ENOG4105N5T	Radical SAM Protein
EFI48_09155	ENOG4108JJA	ABC, transporter
EFI48_09160	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
EFI48_09210	ENOG4105D3R	alkyl hydroperoxide reductase
EFI48_09215	ENOG4105W87	Cbs domain
EFI48_09220	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
EFI48_09225	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
EFI48_09230	ENOG4105VIE	preprotein translocase, subunit YajC
EFI48_09235	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EFI48_09240	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
EFI48_09255	ENOG4106RZ4	Peptidase U32
EFI48_09260	ENOG4105CFP	Peptidase U32
EFI48_09265	ENOG4105XPQ	lipid carrier protein
EFI48_09275	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
EFI48_09280	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
EFI48_09285	ENOG4105C3J	Cysteine desulfurase
EFI48_09290	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
EFI48_09295	ENOG4108Z4V	iron-sulfur cluster assembly
EFI48_09300	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
EFI48_09305	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
EFI48_09310	ENOG4108ZIT	Ferredoxin, 2FE-2S
EFI48_09325	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
EFI48_09330	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EFI48_09340	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
EFI48_09345	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
EFI48_09350	ENOG4105CUT	histidyl-tRNA synthetase
EFI48_09355	ENOG4105N21	Membrane
EFI48_09360	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EFI48_09365	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
EFI48_09370	ENOG4105VPD	cellular component movement
EFI48_09380	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
EFI48_09385	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
EFI48_09390	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_09395	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_09405	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EFI48_09410	ENOG4105C8S	subunit m
EFI48_09415	ENOG4105D65	subunit l
EFI48_09420	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EFI48_09425	ENOG4107UFS	subunit j
EFI48_09430	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EFI48_09435	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
EFI48_09440	ENOG4108IEH	NADH dehydrogenase subunit g
EFI48_09445	ENOG4107QIZ	NADH dehydrogenase
EFI48_09450	ENOG4105GKE	subunit e
EFI48_09455	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EFI48_09460	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EFI48_09465	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EFI48_09485	ENOG4105CUG	Oligopeptidase b
EFI48_09490	ENOG4105D05	Receptor
EFI48_09495	ENOG4105ER2	Ompa motb domain protein
EFI48_09500	ENOG4105E14	MotA TolQ exbB proton channel
EFI48_09515	ENOG4105HA9	of methanol dehydrogenase type
EFI48_09525	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
EFI48_09530	ENOG4105EZ7	amino acid ABC transporter
EFI48_09535	ENOG4106TNF	Periplasmic binding protein
EFI48_09540	ENOG4105EAD	ABC transporter
EFI48_09545	ENOG4105CDA	abc transporter atp-binding protein
EFI48_09555	ENOG4105VFU	Rna-binding protein
EFI48_09560	ENOG4107RGM	aldo keto reductase
EFI48_09570	ENOG4108RU0	short-chain dehydrogenase reductase
EFI48_09585	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_09590	ENOG4105CBN	LysR family transcriptional regulator
EFI48_09595	ENOG4105BZU	Histidine kinase
EFI48_09600	ENOG4105CFC	Transporter
EFI48_09605	ENOG4108DBC	nitroreductase
EFI48_09620	ENOG4108SC4	)-transporter
EFI48_09625	ENOG4105DUM	transcriptional regulator, lysR family
EFI48_09630	ENOG4107R11	Transcriptional regulator
EFI48_09635	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
EFI48_09640	ENOG4105CAT	Cytidine monophosphate kinase
EFI48_09645	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
EFI48_09650	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EFI48_09660	ENOG4105CFV	Tetratricopeptide repeat protein
EFI48_09665	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
EFI48_09680	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EFI48_09685	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
EFI48_09690	ENOG4105VRT	cytoplasmic protein
EFI48_09695	ENOG4108WBT	adenosyltransferase
EFI48_09705	ENOG4107S6Z	Na H antiporter
EFI48_09710	ENOG4107104	thymidine kinase
EFI48_09720	ENOG4108RMJ	sensory transduction regulator
EFI48_09730	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
EFI48_09735	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
EFI48_09740	ENOG4108JQ2	peptide transport system atp-binding protein
EFI48_09745	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
EFI48_09750	ENOG4108EU3	peptide transport system, permease
EFI48_09755	ENOG4108I5W	peptide transport system, permease protein
EFI48_09760	ENOG4108J59	Extracellular solute-binding protein, family 5
EFI48_09765	ENOG4105E51	psp operon transcriptional activator
EFI48_09770	ENOG41087YS	Phage shock protein A
EFI48_09775	ENOG4105YYT	phage shock protein B
EFI48_09785	ENOG4105CM6	amino acid regulated cytosolic protein
EFI48_09790	ENOG4106K28	UPF0283 membrane protein
EFI48_09795	ENOG4108M0I	Transcriptional regulator
EFI48_09800	ENOG4107TYH	extracellular solute-binding protein family 1
EFI48_09805	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EFI48_09810	ENOG4105D81	ABC transporter, permease
EFI48_09815	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
EFI48_09820	ENOG4105C26	Dehydrogenase
EFI48_09825	ENOG4105MIR	Phenylalanine 4-monooxygenase
EFI48_09830	ENOG41090A4	Pterin carbinolamine dehydratase
EFI48_09850	ENOG4108KHX	Diguanylate cyclase
EFI48_09855	ENOG41090EK	ompa motb domain protein
EFI48_09860	ENOG4105EE5	Membrane protein terC
EFI48_09870	ENOG4105MH2	YfcL protein
EFI48_09880	ENOG4105C28	cystathionine
EFI48_09890	ENOG4108RYK	Nad-dependent epimerase dehydratase
EFI48_09895	ENOG4105CR8	Transcriptional regulator
EFI48_09900	ENOG41064T2	transcriptional regulator, lysR family
EFI48_09905	ENOG4105DJB	Major Facilitator Superfamily
EFI48_09910	ENOG4105EUB	pirin domain protein
EFI48_09915	ENOG4105CHJ	isochorismatase hydrolase
EFI48_09920	ENOG4105EXG	Transcriptional regulator
EFI48_09925	ENOG4105DZ2	Transcriptional regulator
EFI48_09930	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
EFI48_09940	ENOG4108KB2	LysR family Transcriptional regulator
EFI48_09945	ENOG4105CS2	ec 3.2.1.21
EFI48_09950	ENOG4105DDY	UPF0142 protein ycaO
EFI48_09955	ENOG4105TMB	Formate nitrite transporter
EFI48_09960	ENOG4105C6N	Formate acetyltransferase
EFI48_09980	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
EFI48_09985	ENOG4105C8P	)-transporter
EFI48_09990	ENOG4105K63	Thioredoxin
EFI48_09995	ENOG4105BZU	Histidine kinase
EFI48_10000	ENOG4105BZ1	(ABC) transporter
EFI48_10005	ENOG4105BZ1	(ABC) transporter
EFI48_10015	ENOG4105WQ3	Rna-binding protein
EFI48_10030	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
EFI48_10060	ENOG4105K5X	acetyltransferase
EFI48_10070	ENOG4105BZN	citrate synthase
EFI48_10075	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
EFI48_10080	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
EFI48_10085	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
EFI48_10090	ENOG4105E33	succinate dehydrogenase
EFI48_10095	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
EFI48_10100	ENOG4105C7S	Dehydrogenase
EFI48_10105	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
EFI48_10110	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
EFI48_10125	ENOG4106HK8	GPR1 FUN34 yaaH family protein
EFI48_10145	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
EFI48_10155	ENOG4105E39	Enoyl-CoA hydratase
EFI48_10160	ENOG4107QX3	carboxylase
EFI48_10165	ENOG4105C1G	acyl-Coa dehydrogenase
EFI48_10170	ENOG4105C1G	acyl-Coa dehydrogenase
EFI48_10175	ENOG4105E39	Enoyl-CoA hydratase
EFI48_10180	ENOG4105E39	Enoyl-CoA hydratase
EFI48_10185	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
EFI48_10190	ENOG4105CHR	reductase
EFI48_10195	ENOG4105D5Q	Arginine ornithine antiporter
EFI48_10200	ENOG4105HF0	Membrane
EFI48_10215	ENOG4107RTG	Major Facilitator superfamily
EFI48_10225	ENOG4105ENX	hydrolase
EFI48_10230	ENOG4105EQ2	LysR family Transcriptional regulator
EFI48_10240	ENOG4105BZU	Histidine kinase
EFI48_10270	ENOG4105F8J	Adenylate Guanylate cyclase
EFI48_10275	ENOG4105CG5	Glycosyl transferase (Group 1
EFI48_10285	ENOG4107QZ7	Cellulose synthase catalytic subunit
EFI48_10290	ENOG4108KMV	Glycosyl transferase (Group 1
EFI48_10335	ENOG4107EF8	Glycosyl transferase (Group 1
EFI48_10355	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
EFI48_10360	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
EFI48_10370	ENOG4105E3S	small subunit
EFI48_10375	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EFI48_10380	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
EFI48_10385	ENOG4105DPX	Hydrogenase, large subunit
EFI48_10390	ENOG4108USZ	hydrogenase
EFI48_10395	ENOG4108WGS	hydrogenase 2-specific chaperone
EFI48_10405	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EFI48_10410	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
EFI48_10420	ENOG4105EFJ	Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity)
EFI48_10425	ENOG4107RSS	Hydrogenase accessory protein HypB
EFI48_10430	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
EFI48_10435	ENOG4105C45	hydrogenase expression formation protein (HypE)
EFI48_10440	ENOG4105CQS	hydrogenase expression formation protein HypD
EFI48_10445	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
EFI48_10455	ENOG4105EM7	Selenocysteine-specific translation elongation factor
EFI48_10460	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
EFI48_10465	ENOG4108MG9	hydrogenase 3 maturation protease
EFI48_10470	ENOG4105I6X	formate hydrogenlyase maturation
EFI48_10475	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
EFI48_10485	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
EFI48_10490	ENOG4107TDF	Formate hydrogenlyase subunit 4
EFI48_10495	ENOG4108JPZ	Monovalent cation H antiporter subunit D
EFI48_10500	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
EFI48_10505	ENOG4105DFH	Transport of potassium into the cell (By similarity)
EFI48_10510	ENOG4105ESI	atpase involved in dna repair
EFI48_10520	ENOG4108RC0	Electron transport protein
EFI48_10540	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
EFI48_10545	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EFI48_10550	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
EFI48_10555	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
EFI48_10565	ENOG4105C0F	tryptophanase EC 4.1.99.1
EFI48_10570	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
EFI48_10575	ENOG41067MG	lrgb family
EFI48_10585	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
EFI48_10595	ENOG4105CJB	Exodeoxyribonuclease I
EFI48_10600	ENOG4105C4X	radical SAM domain protein
EFI48_10625	ENOG4107QVM	von Willebrand factor, type A
EFI48_10645	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EFI48_10650	ENOG4105ENH	Sulfatase
EFI48_10655	ENOG4105DHT	Metal Dependent Phosphohydrolase
EFI48_10665	ENOG4105CQ7	ATP-dependent helicase
EFI48_10675	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
EFI48_10685	ENOG4105CHU	acetyl-coa acetyltransferase
EFI48_10690	ENOG4105D58	Diguanylate phosphodiesterase
EFI48_10695	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
EFI48_10700	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
EFI48_10710	ENOG4105EMN	RNA polymerase sigma factor
EFI48_10740	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EFI48_10745	ENOG4105CHU	acetyl-coa acetyltransferase
EFI48_10750	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
EFI48_10755	ENOG4105ED1	spovr family
EFI48_10760	ENOG4106AKX	UPF0229 protein
EFI48_10765	ENOG4105CYN	Serine protein kinase
EFI48_10770	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EFI48_10775	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
EFI48_10785	ENOG4105C44	Serine transporter
EFI48_10790	ENOG4105P8F	nudix hydrolase
EFI48_10805	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
EFI48_10825	ENOG4105CVJ	phosphoglycerate mutase
EFI48_10830	ENOG4105BZU	Histidine kinase
EFI48_10835	ENOG4108DG9	Smr protein MutS2
EFI48_10840	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
EFI48_10845	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
EFI48_10855	ENOG4105C1J	atp-dependent rna helicase
EFI48_10865	ENOG4105WJG	Glutathione
EFI48_10875	ENOG4105E0U	tyrosine-specific transport protein
EFI48_10880	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
EFI48_10885	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
EFI48_10890	ENOG4105DE4	1-phosphofructokinase
EFI48_10895	ENOG4105DM4	PTS System
EFI48_10900	ENOG4105C03	ribonuclease
EFI48_10905	ENOG4105EI2	Pseudouridine synthase
EFI48_10915	ENOG4108UHJ	MAF-like protein
EFI48_10920	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
EFI48_10925	ENOG4105VGS	50s ribosomal protein l32
EFI48_10930	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
EFI48_10935	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EFI48_10940	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
EFI48_10945	ENOG4105CHR	reductase
EFI48_10950	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
EFI48_10955	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EFI48_10960	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
EFI48_10965	ENOG4105HHA	aminodeoxychorismate lyase
EFI48_10970	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
EFI48_10975	ENOG4107QRG	dna polymerase iii
EFI48_10980	ENOG4105F8V	Hydrolase, tatD family
EFI48_10995	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EFI48_11000	ENOG4105DY2	Paraquat-inducible protein b
EFI48_11005	ENOG4105F1S	paraquat-inducible protein a
EFI48_11015	ENOG4105CR4	methylisocitrate lyase
EFI48_11020	ENOG4105BZN	citrate synthase
EFI48_11025	ENOG4105DXD	2-methylcitrate dehydratase
EFI48_11065	ENOG4105PDP	Short chain dehydrogenase
EFI48_11070	ENOG4108KTS	Acetyltransferase and hydrolase with the alpha beta hydrolase fold
EFI48_11075	ENOG4105X2V	dna damage-inducible protein
EFI48_11110	ENOG4105DAN	ATP-dependent protease
EFI48_11115	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
EFI48_11120	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
EFI48_11125	ENOG4105C5H	ABC transporter
EFI48_11135	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
EFI48_11145	ENOG4105NRA	50s ribosomal protein l31 type b
EFI48_11155	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
EFI48_11160	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
EFI48_11165	ENOG4105C7I	Dehydrogenase
EFI48_11175	ENOG4105CD8	aminopeptidase N
EFI48_11180	ENOG4105CN1	protease
EFI48_11185	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
EFI48_11190	ENOG4108ZGC	gaf domain protein
EFI48_11200	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
EFI48_11215	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
EFI48_11225	ENOG4105C59	p-type ATPase
EFI48_11240	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
EFI48_11245	ENOG4105Q9Y	Universal stress protein
EFI48_11250	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
EFI48_11270	ENOG4105F38	ABC transporter, permease
EFI48_11275	ENOG4105D38	putrescine abc transporter
EFI48_11295	ENOG4108K3A	Glutathione S-transferase
EFI48_11300	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
EFI48_11305	ENOG4105C2J	ABC transporter
EFI48_11310	ENOG4105CNN	ABC, transporter
EFI48_11315	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
EFI48_11320	ENOG4108RVA	ribokinase
EFI48_11325	ENOG4105ETE	Transcriptional regulator (LacI family
EFI48_11330	ENOG4105BZU	Histidine kinase
EFI48_11340	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
EFI48_11355	ENOG4105BZU	Histidine kinase
EFI48_11360	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
EFI48_11365	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
EFI48_11370	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
EFI48_11375	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
EFI48_11385	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
EFI48_11390	ENOG4105C22	threonyL-tRNA synthetase
EFI48_11410	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EFI48_11415	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
EFI48_11420	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
EFI48_11425	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EFI48_11430	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
EFI48_11435	ENOG4105XPH	Ferredoxin
EFI48_11440	ENOG4105CA3	membrane-bound lytic murein transglycosylase
EFI48_11445	ENOG4105XZD	Fe-S protein
EFI48_11450	ENOG4105CJ3	phosphate transporter
EFI48_11455	ENOG4105DHP	deoxycytidine triphosphate deaminase
EFI48_11460	ENOG4105DBI	uridine monophosphokinase
EFI48_11465	ENOG4105D1F	ATP-binding protein
EFI48_11470	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
EFI48_11480	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
EFI48_11485	ENOG4108N3W	hemolysin secretion protein
EFI48_11490	ENOG4105I03	Flagellin
EFI48_11495	ENOG4105DR4	Methyltransferase
EFI48_11500	ENOG4105FAT	Acyl-transferase
EFI48_11510	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
EFI48_11515	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
EFI48_11520	ENOG4105C5X	domain protein
EFI48_11535	ENOG4105CEY	Amp-dependent synthetase and ligase
EFI48_11540	ENOG4108MXF	Alpha Beta Hydrolase
EFI48_11550	ENOG41072GX	Peptidase M22 Glycoprotease
EFI48_11555	ENOG4105DVT	helicase
EFI48_11565	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
EFI48_11570	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
EFI48_11575	ENOG4105CIH	Imidazole acetol-phosphate transaminase
EFI48_11580	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
EFI48_11585	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
EFI48_11590	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
EFI48_11595	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
EFI48_11600	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
EFI48_11610	ENOG4105BZU	Histidine kinase
EFI48_11615	ENOG4105CEY	Amp-dependent synthetase and ligase
EFI48_11625	ENOG4107MBR	17 kDa surface antigen
EFI48_11630	ENOG4108UTP	(2Fe-2S)-binding domain protein
EFI48_11635	ENOG4108HR6	Dehydrogenase
EFI48_11640	ENOG4105C7W	Xanthine dehydrogenase
EFI48_11645	ENOG4105C7N	Xanthine uracil vitamin C permease
EFI48_11650	ENOG4107QUY	Guanine deaminase
EFI48_11655	ENOG4105C2W	permease
EFI48_11660	ENOG4105C7W	Xanthine dehydrogenase
EFI48_11665	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
EFI48_11670	ENOG4107UUR	Chlorohydrolase aminohydrolase
EFI48_11675	ENOG4105BZ8	glutamate synthase
EFI48_11680	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
EFI48_11685	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
EFI48_11690	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
EFI48_11700	ENOG4108Q5Y	Membrane
EFI48_11705	ENOG4105C5B	carbamate kinase
EFI48_11715	ENOG4107S4Y	M20 DapE family protein YgeY
EFI48_11720	ENOG4107RCH	Diaminopropionate ammonia-lyase
EFI48_11725	ENOG4105IW6	Carbamoyltransferase
EFI48_11760	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EFI48_11775	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
EFI48_11780	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
EFI48_11785	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
EFI48_11790	ENOG4106371	Methyltransferase
EFI48_11795	ENOG4107S90	membrAne
EFI48_11805	ENOG4105CTQ	phosphohexokinase
EFI48_11810	ENOG4105CK2	sodium dicarboxylate symporter
EFI48_11815	ENOG4105NBK	UPF0345 protein
EFI48_11820	ENOG4105EJQ	L-serine dehydratase
EFI48_11830	ENOG4105EJQ	L-serine dehydratase
EFI48_11835	ENOG4105VNG	YcgL domain-containing protein
EFI48_11840	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
EFI48_11845	ENOG4107QMS	site-determining protein
EFI48_11850	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
EFI48_11860	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
EFI48_11865	ENOG4105XW2	UPF0263 protein
EFI48_11905	ENOG4108SXK	Transporter Drug Metabolite Exporter family
EFI48_11910	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
EFI48_11915	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
EFI48_11925	ENOG4108R6K	riboflavin synthase, subunit alpha
EFI48_11935	ENOG4105W1I	UPF0253 protein
EFI48_11970	ENOG4108JUB	Transcriptional regulator
EFI48_11985	ENOG4108VWS	Yaeq family
EFI48_12000	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EFI48_12005	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
EFI48_12010	ENOG4105DQR	SNARE associated Golgi
EFI48_12020	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
EFI48_12035	ENOG4105D0C	transport protein
EFI48_12040	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
EFI48_12045	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
EFI48_12060	ENOG4105CEE	C4-dicarboxylate transporter
EFI48_12075	ENOG4108VKG	metal-dependent hydrolase
EFI48_12090	ENOG4105CQ2	DNA polymerase
EFI48_12115	ENOG4105D1S	lipid A biosynthesis
EFI48_12120	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
EFI48_12130	ENOG4105DUM	transcriptional regulator, lysR family
EFI48_12135	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
EFI48_12140	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
EFI48_12145	ENOG4107QMP	dna polymerase iii subunits gamma and tau
EFI48_12150	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
EFI48_12155	ENOG4105WD1	Membrane
EFI48_12160	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
EFI48_12175	ENOG4105PAD	Hydrolase
EFI48_12180	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
EFI48_12230	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
EFI48_12245	ENOG4105VP0	transcriptional regulator, lysR family
EFI48_12250	ENOG4105EJ9	Membrane
EFI48_12255	ENOG4106IUH	DTW domain containing protein
EFI48_12260	ENOG4105E2R	ROK family
EFI48_12265	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_12270	ENOG4105K5B	UPF0225 protein
EFI48_12275	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
EFI48_12280	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
EFI48_12285	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
EFI48_12300	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
EFI48_12305	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
EFI48_12310	ENOG4105DVI	reductase, NrfD
EFI48_12315	ENOG4105DA4	cytochrome c-type biogenesis protein
EFI48_12320	ENOG4107QX9	Thiol disulfide interChange protein
EFI48_12325	ENOG4108DMF	Cytochrome C biogenesis protein
EFI48_12330	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
EFI48_12335	ENOG4108JPW	Aminotransferase
EFI48_12340	ENOG4107STF	Involved in phosphonate degradation (By similarity)
EFI48_12350	ENOG4105C4Y	ABC transporter
EFI48_12360	ENOG4107RCV	ABC transporter, permease
EFI48_12365	ENOG4105CJP	fad dependent oxidoreductase
EFI48_12370	ENOG4108J1Q	
EFI48_12385	ENOG4105BZG	amino acid carrier protein
EFI48_12415	ENOG4105ED4	portal protein
EFI48_12420	ENOG41060WC	Enoyl-CoA hydratase
EFI48_12435	ENOG41062QD	Membrane
EFI48_12440	ENOG4107QN1	sodium solute
EFI48_12445	ENOG4105C5H	ABC transporter
EFI48_12450	ENOG4105EIN	peptidylprolyl cis-trans isomerase
EFI48_12455	ENOG4105K70	DNA-binding protein
EFI48_12460	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
EFI48_12465	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
EFI48_12470	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
EFI48_12475	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
EFI48_12495	ENOG4105D60	lipoprotein releasing system transmembrane protein
EFI48_12500	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EFI48_12505	ENOG4105D60	lipoprotein releasing system transmembrane protein
EFI48_12515	ENOG4108JA2	transcriptioN-repair coupling factor
EFI48_12520	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EFI48_12525	ENOG4108J59	Extracellular solute-binding protein, family 5
EFI48_12530	ENOG4108IPJ	Membrane
EFI48_12540	ENOG4108BY2	phosphohistidine phosphatase
EFI48_12545	ENOG4107QXK	peptidase
EFI48_12550	ENOG4105FQ6	thiopurine methyltransferase
EFI48_12560	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
EFI48_12565	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EFI48_12585	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EFI48_12590	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EFI48_12600	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EFI48_12605	ENOG4105FDP	GntR family transcriptional regulator
EFI48_12610	ENOG4105DM4	PTS System
EFI48_12615	ENOG4105C8I	hydrolase, family 38
EFI48_12620	ENOG4105CPF	Cell wall formation (By similarity)
EFI48_12635	ENOG4105C1J	atp-dependent rna helicase
EFI48_12640	ENOG4105D4P	Coproporphyrinogen iii oxidase
EFI48_12645	ENOG4108NVR	Methyl-accepting chemotaxis
EFI48_12650	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EFI48_12655	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
EFI48_12660	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
EFI48_12665	ENOG4105C10	Electron transfer flavoprotein
EFI48_12670	ENOG4105BZJ	Electron transfer flavoprotein
EFI48_12675	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EFI48_12680	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EFI48_12685	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
EFI48_12690	ENOG4107QUT	magnesium and cobalt transport protein CorA
EFI48_12695	ENOG4105QZU	Inner membrane protein YfeZ
EFI48_12705	ENOG4105F3T	(LipO)protein
EFI48_12720	ENOG4105BZU	Histidine kinase
EFI48_12735	ENOG4107RE1	Inosine-guanosine kinase
EFI48_12745	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
EFI48_12750	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
EFI48_12755	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
EFI48_12760	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
EFI48_12765	ENOG4105E96	Colicin v production protein
EFI48_12770	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
EFI48_12775	ENOG4105D1H	recombination factor protein RarA
EFI48_12780	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
EFI48_12785	ENOG4105CNU	cell division protein FtsK
EFI48_12790	ENOG4105EW9	transcriptional regulator AsnC family
EFI48_12795	ENOG4105DCF	alanine dehydrogenase
EFI48_12800	ENOG4105C3M	thioredoxin reductase
EFI48_12805	ENOG4105BZU	Histidine kinase
EFI48_12810	ENOG4107MBR	17 kDa surface antigen
EFI48_12815	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
EFI48_12820	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
EFI48_12825	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
EFI48_12830	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EFI48_12835	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
EFI48_12840	ENOG4105VEQ	Cold shock protein
EFI48_12845	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
EFI48_12865	ENOG4107EXC	regulatoR
EFI48_12870	ENOG4105JJR	Histidine kinase
EFI48_12880	ENOG4105FF5	Membrane
EFI48_12905	ENOG4108J1Q	
EFI48_12965	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EFI48_12980	ENOG4105CHH	sulfate transporter
EFI48_13005	ENOG4105C9U	ATP-dependent DNA helicase RecQ
EFI48_13045	ENOG4105C2C	drug resistance transporter, Bcr CflA
EFI48_13060	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
EFI48_13080	ENOG4105F2Z	3-oxoadipate enol-lactonase
EFI48_13100	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
EFI48_13105	ENOG4107QZM	n-acetylglutamate synthase
EFI48_13110	ENOG4105CFH	Aspartokinase
EFI48_13120	ENOG4107T7U	Sulfatase
EFI48_13125	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
EFI48_13130	ENOG4108NRW	Phospholipase, patatin family
EFI48_13135	ENOG4105D5B	Sulfite reductase, subunit A
EFI48_13140	ENOG4107SHJ	sulfite reductase subunit b
EFI48_13145	ENOG410810Y	Sulfite reductase
EFI48_13150	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
EFI48_13160	ENOG4105K8R	UPF0145 protein
EFI48_13165	ENOG4108S3P	Sporulation domain protein
EFI48_13170	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
EFI48_13175	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
EFI48_13180	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
EFI48_13190	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
EFI48_13195	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
EFI48_13200	ENOG4105EYK	Phosphatidylglycerophosphatase B
EFI48_13205	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
EFI48_13210	ENOG4105D3Y	Na H antiporter
EFI48_13215	ENOG4105BZU	Histidine kinase
EFI48_13230	ENOG4105KA0	thioesterase Superfamily protein
EFI48_13240	ENOG4105CQB	FAD linked oxidase domain protein
EFI48_13250	ENOG4105EE5	Membrane protein terC
EFI48_13255	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EFI48_13265	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EFI48_13270	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
EFI48_13275	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
EFI48_13285	ENOG4105CAQ	asparagine synthetase
EFI48_13315	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
EFI48_13320	ENOG4105WH1	Two component transcriptional regulator luxr family
EFI48_13325	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
EFI48_13330	ENOG4105W49	UPF0434 protein
EFI48_13335	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
EFI48_13345	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
EFI48_13360	ENOG4105CGF	Aromatic amino acid aminotransferase
EFI48_13370	ENOG4105CVI	Transcriptional regulator
EFI48_13375	ENOG4108WFC	UPF0438 protein yifE
EFI48_13380	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
EFI48_13385	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
EFI48_13390	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
EFI48_13395	ENOG4105E98	transcriptional regulator DeoR family
EFI48_13400	ENOG4105CXY	transporter
EFI48_13405	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
EFI48_13410	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
EFI48_13415	ENOG41069D7	Methyl-accepting chemotaxis
EFI48_13425	ENOG4105HEI	LysR family (Transcriptional regulator
EFI48_13445	ENOG4105CV8	reductase
EFI48_13455	ENOG4105F27	Major Facilitator
EFI48_13460	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
EFI48_13475	ENOG4105E18	UPF0276 protein
EFI48_13495	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
EFI48_13500	ENOG4105C4M	(Ubiquinol oxidase) subunit I
EFI48_13505	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
EFI48_13510	ENOG4108Q2J	Inner membrane protein YebE
EFI48_13515	ENOG4105NAU	thioesterase Superfamily protein
EFI48_13520	ENOG4106428	Protein of unknown function (DUF2496)
EFI48_13530	ENOG4105DJ2	Major Facilitator Superfamily
EFI48_13535	ENOG4105FE9	pseudouridine synthase
EFI48_13545	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
EFI48_13555	ENOG4108R4U	Hnh endonuclease
EFI48_13560	ENOG4105DGN	Electron transport complex
EFI48_13565	ENOG4108R3D	Electron transport complex
EFI48_13575	ENOG4105D6A	Electron transport complex
EFI48_13585	ENOG4105DZB	Electron transport complex
EFI48_13590	ENOG4105CSM	endonuclease III
EFI48_13595	ENOG4108UYE	Lactoylglutathione lyase
EFI48_13600	ENOG4105EIY	sodium-type flagellar protein motY
EFI48_13635	ENOG4105DVT	helicase
EFI48_13645	ENOG4105DGU	Histone deacetylase
EFI48_13650	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
EFI48_13655	ENOG4105G6Z	alkaline phosphatase
EFI48_13675	ENOG4105NXH	GreA GreB family elongation factor
EFI48_13680	ENOG4108KX4	response regulator
EFI48_13685	ENOG4105BZU	Histidine kinase
EFI48_13690	ENOG4105CXY	transporter
EFI48_13695	ENOG4105BZU	Histidine kinase
EFI48_13700	ENOG4106PMH	Extracellular solute-binding protein family 3
EFI48_13705	ENOG4105E5Q	amino acid AbC transporter
EFI48_13710	ENOG4105CDA	abc transporter atp-binding protein
EFI48_13725	ENOG4105D5Q	Arginine ornithine antiporter
EFI48_13730	ENOG4105C3R	Methionine synthase
EFI48_13745	ENOG4105C37	(CBS) domain
EFI48_13755	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
EFI48_13760	ENOG4105E2Z	phosphate ABC transporter (Permease
EFI48_13765	ENOG4105C8U	phosphate abc transporter
EFI48_13770	ENOG4108Z6B	deaminase
EFI48_13780	ENOG4107QP3	malate synthase g
EFI48_13785	ENOG4108I9X	Isocitrate lyase
EFI48_13800	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
EFI48_13805	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
EFI48_13810	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
EFI48_13815	ENOG4107QNR	UPF0135 protein
EFI48_13820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EFI48_13825	ENOG4105BZU	Histidine kinase
EFI48_13830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EFI48_13840	ENOG4105RH4	Glycine cleavage system transcriptional repressor
EFI48_13845	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
EFI48_13850	ENOG4105C9X	ppx gppa phosphatase
EFI48_13855	ENOG4105CJW	magnesium transporter
EFI48_13860	ENOG4105DTJ	flagellar hook-associated protein
EFI48_13870	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
EFI48_13875	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EFI48_13880	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
EFI48_13885	ENOG4105CGA	flagellar basal-body rod protein FlgG
EFI48_13890	ENOG4108KPB	Flagellar basal-body rod protein FlgF
EFI48_13895	ENOG4105BZE	flagellar hook protein, FlgE
EFI48_13905	ENOG4108ZC9	flagellar basal-body rod protein flgc
EFI48_13910	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
EFI48_13915	ENOG4105BZU	Histidine kinase
EFI48_13920	ENOG4107R88	Chemotaxis protein (CheV)
EFI48_13925	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
EFI48_13940	ENOG4108RE9	Phosphodiesterase
EFI48_13945	ENOG4107QSI	ABC, transporter
EFI48_13955	ENOG4105I08	Pseudouridine synthase
EFI48_13960	ENOG4105CPI	Metal Dependent Phosphohydrolase
EFI48_13970	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EFI48_13975	ENOG4105F1A	Pyruvate formate-lyase
EFI48_13980	ENOG4105C6N	Formate acetyltransferase
EFI48_13985	ENOG4105N2W	Transcriptional regulator
EFI48_13990	ENOG4105E43	Extracellular solute-binding protein, family 5
EFI48_14015	ENOG4105VEQ	Cold shock protein
EFI48_14020	ENOG4107QSN	dihydrolipoamide acetyltransferase
EFI48_14025	ENOG4105CPP	Dehydrogenase, E1 component
EFI48_14030	ENOG4107RUY	(E1 component), alpha subunit
EFI48_14040	ENOG4105C0W	non-ribosomal peptide synthetase
EFI48_14045	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
EFI48_14050	ENOG4105WQI	isochorismatase
EFI48_14055	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
EFI48_14060	ENOG4105E4F	Isochorismate synthase
EFI48_14065	ENOG4105D05	Receptor
EFI48_14070	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
EFI48_14075	ENOG41060NJ	transcriptional regulator
EFI48_14080	ENOG4107SC1	transglycosylase
EFI48_14085	ENOG4105BZU	Histidine kinase
EFI48_14090	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
EFI48_14110	ENOG4105MA0	exported protein
EFI48_14115	ENOG4105CFU	surface antigen
EFI48_14125	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
EFI48_14135	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
EFI48_14145	ENOG4105VNH	ABC transporter solute-binding protein
EFI48_14155	ENOG4108VGW	abc transporter atp-binding protein
EFI48_14160	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
EFI48_14165	ENOG4105CVE	Lytic murein transglycosylase
EFI48_14180	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
EFI48_14185	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
EFI48_14190	ENOG4105EV9	Alpha Beta Hydrolase
EFI48_14200	ENOG4105NNH	LexA regulated protein
EFI48_14205	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
EFI48_14215	ENOG41090R7	Ferric uptake
EFI48_14220	ENOG4105CX6	glutaminyL-tRNA synthetase
EFI48_14225	ENOG4105E2D	ec 3.2.1.52
EFI48_14230	ENOG4105CI1	PTS System
EFI48_14235	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
EFI48_14240	ENOG4105CE4	GlcNAc 6-P deacetylase
EFI48_14245	ENOG4105E2R	ROK family
EFI48_14250	ENOG4105DIJ	Phosphoethanolamine transferase
EFI48_14255	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_14260	ENOG4108HRK	Histidine kinase
EFI48_14265	ENOG4108NEV	two component transcriptional regulator, LytTR family
EFI48_14275	ENOG4105KK7	inner membrane protein YiaW
EFI48_14280	ENOG4105EFX	secretion protein, HlyD family
EFI48_14285	ENOG4105CFI	type iii restriction protein res subunit
EFI48_14290	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
EFI48_14295	ENOG41090BQ	Glutaredoxin
EFI48_14310	ENOG4105NAU	thioesterase Superfamily protein
EFI48_14315	ENOG4108535	NAD dependent epimerase/dehydratase family
EFI48_14320	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
EFI48_14335	ENOG4105QVC	MOSC domain-containing protein
EFI48_14335	ENOG4105QVC	MOSC domain-containing protein
EFI48_14340	ENOG4107SDU	Methyl-accepting chemotaxis
EFI48_14345	ENOG4105D0M	Protease HtpX homolog
EFI48_14350	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
EFI48_14355	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
EFI48_14360	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
EFI48_14365	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
EFI48_14370	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
EFI48_14385	ENOG4105C5S	asparaginyl-tRNA synthetase
EFI48_14395	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
EFI48_14405	ENOG4105CH2	amidohydrolase
EFI48_14410	ENOG4105CEE	C4-dicarboxylate transporter
EFI48_14420	ENOG4105KUZ	arsenate reductase
EFI48_14425	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
EFI48_14440	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
EFI48_14455	ENOG410829K	Lysine exporter protein (Lyse ygga)
EFI48_14465	ENOG4105RX8	Protein of unknown function (DUF1523)
EFI48_14480	ENOG4105DU0	nucleoside hydrolase
EFI48_14485	ENOG4105D3G	Pseudouridine synthase
EFI48_14490	ENOG4107SXA	Phosphorylase
EFI48_14495	ENOG4105C0A	alcohol dehydrogenase
EFI48_14535	ENOG4107U53	septum site-determining protein minD
EFI48_14575	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EFI48_14580	ENOG4105K4T	epimerase
EFI48_14590	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
EFI48_14595	ENOG4105BZU	Histidine kinase
EFI48_14600	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EFI48_14605	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EFI48_14610	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EFI48_14615	ENOG4105EFX	secretion protein, HlyD family
EFI48_14650	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
EFI48_14665	ENOG4105WBN	Transcriptional regulator (LacI family
EFI48_14670	ENOG4108HKT	sucrose-6-phosphate hydrolase
EFI48_14680	ENOG4105D7K	pfkb domain protein
EFI48_14690	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
EFI48_14695	ENOG4105CFG	Acts as a chaperone (By similarity)
EFI48_14700	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EFI48_14705	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
EFI48_14710	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
EFI48_14715	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
EFI48_14720	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
EFI48_14725	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
EFI48_14730	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
EFI48_14735	ENOG4108YX2	DNA-binding protein
EFI48_14745	ENOG4105E3R	(LipO)protein
EFI48_14765	ENOG4105D75	Capsular exopolysaccharide family
EFI48_14770	ENOG4107ZF2	Phosphatase
EFI48_14775	ENOG4105DAY	polysaccharide export protein
EFI48_14795	ENOG4107QRS	glycosyltransferase group 2 family protein
EFI48_14805	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
EFI48_14820	ENOG4105ESV	Glycosyl transferase, family 4
EFI48_14830	ENOG4105ESV	Glycosyl transferase, family 4
EFI48_14860	ENOG4105EY8	ABC transporter
EFI48_14875	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
EFI48_14880	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
EFI48_14890	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
EFI48_14895	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
EFI48_14900	ENOG4105BZS	acriflavin resistance protein
EFI48_14905	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
EFI48_14910	ENOG4108IG5	Transcriptional regulator
EFI48_14925	ENOG4105VYW	UPF0251 protein
EFI48_14940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_14945	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
EFI48_14970	ENOG4105D98	threonine synthase
EFI48_14975	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
EFI48_14990	ENOG4106FVC	RNA methyltransferase
EFI48_14995	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
EFI48_15000	ENOG4105C29	acyl-CoA thioesterase
EFI48_15010	ENOG4105FE9	pseudouridine synthase
EFI48_15015	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
EFI48_15025	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
EFI48_15030	ENOG4105DB7	PHP domain protein
EFI48_15035	ENOG4105CRQ	synthase (Component I)
EFI48_15040	ENOG4108EFP	Anthranilate synthase component II
EFI48_15045	ENOG4108I0Q	anthranilate phosphoribosyltransferase
EFI48_15050	ENOG4105DK0	Indole-3-glycerol phosphate synthase
EFI48_15055	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
EFI48_15060	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
EFI48_15095	ENOG4105D9N	nucleoside
EFI48_15105	ENOG4105D6J	arsenicaL-resistance protein
EFI48_15135	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
EFI48_15145	ENOG41065U4	response regulator
EFI48_15160	ENOG4108JJ9	ABC, transporter
EFI48_15165	ENOG4108JJ8	(ABC) transporter
EFI48_15185	ENOG4108R96	Methyltransferase, YaeB family
EFI48_15190	ENOG4105CPW	cytochrome b561
EFI48_15200	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EFI48_15230	ENOG4105CJP	fad dependent oxidoreductase
EFI48_15235	ENOG4107VRI	Transcriptional regulator
EFI48_15240	ENOG4105C26	Dehydrogenase
EFI48_15245	ENOG4108JPW	Aminotransferase
EFI48_15250	ENOG4105CUB	amino acid
EFI48_15260	ENOG4105CUB	amino acid
EFI48_15270	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EFI48_15275	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
EFI48_15280	ENOG4105DH7	May be involved in recombination (By similarity)
EFI48_15290	ENOG4107RH8	nuclease SbcCD subunit D
EFI48_15295	ENOG4105EYH	Exonuclease
EFI48_15310	ENOG4105CA9	Pyruvate kinase
EFI48_15315	ENOG4105EGS	Mechanosensitive ion channel
EFI48_15325	ENOG4105C9K	Endothelin-converting enzyme 1
EFI48_15330	ENOG4105BZU	Histidine kinase
EFI48_15335	ENOG4105C5Y	PTS System
EFI48_15345	ENOG4105KZ7	phosphocarrier protein hpr
EFI48_15350	ENOG4105C6T	cysteine synthase
EFI48_15370	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
EFI48_15390	ENOG4105GVR	general secretion pathway protein D
EFI48_15395	ENOG4107QHF	type ii secretion system protein e
EFI48_15400	ENOG4105D7Q	type ii secretion system
EFI48_15405	ENOG4108VAU	general secretion pathway protein G
EFI48_15450	ENOG4108MN8	Membrane
EFI48_15455	ENOG4105EM2	membrane
EFI48_15460	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
EFI48_15465	ENOG4105EP9	oxidoreductase
EFI48_15490	ENOG410600T	transposase
EFI48_15495	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EFI48_15500	ENOG4105CCT	upf0313 protein
EFI48_15510	ENOG4105J12	Multidrug resistance protein mdtN
EFI48_15520	ENOG4105D78	K07001 NTE family protein
EFI48_15525	ENOG4107R7I	amino acid
EFI48_15540	ENOG4105UYK	outer membrane protein a
EFI48_15555	ENOG4105UYK	outer membrane protein a
EFI48_15560	ENOG4107R1I	NAD-dependent malic enzyme
EFI48_15565	ENOG4105ECQ	AraC Family Transcriptional Regulator
EFI48_15570	ENOG4105UQX	Mate efflux family protein
EFI48_15575	ENOG4105RKX	Protein of unknown function (DUF2498)
EFI48_15580	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
EFI48_15585	ENOG4105C2W	permease
EFI48_15590	ENOG4108KMH	lipoate-protein ligase a
EFI48_15595	ENOG4105BZG	amino acid carrier protein
EFI48_15620	ENOG4105PTV	Nudix Hydrolase
EFI48_15635	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EFI48_15640	ENOG4106N3A	copper homeostasis protein cutc
EFI48_15655	ENOG4105ERG	peptidase m48, ste24p
EFI48_15665	ENOG4105BZU	Histidine kinase
EFI48_15670	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
EFI48_15675	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
EFI48_15680	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
EFI48_15685	ENOG4105C26	Dehydrogenase
EFI48_15695	ENOG4108IPJ	Membrane
EFI48_15700	ENOG4106YYS	transcriptional regulatory protein
EFI48_15705	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
EFI48_15710	ENOG4107R1I	NAD-dependent malic enzyme
EFI48_15725	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
EFI48_15730	ENOG4105J12	Multidrug resistance protein mdtN
EFI48_15760	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
EFI48_15765	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
EFI48_15775	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
EFI48_15780	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
EFI48_15785	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
EFI48_15790	ENOG4105EXN	Sulfate transport protein CysZ
EFI48_15795	ENOG4105EN6	Membrane
EFI48_15805	ENOG4105EAQ	(twin-arginine translocation) pathway signal
EFI48_15810	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
EFI48_15840	ENOG4107T9C	Alpha amylase catalytic region
EFI48_15875	ENOG4105BZU	Histidine kinase
EFI48_15880	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
EFI48_15885	ENOG4105C9K	Endothelin-converting enzyme 1
EFI48_15895	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
EFI48_15900	ENOG4105CXN	decarboxylase
EFI48_15905	ENOG4105D5Q	Arginine ornithine antiporter
EFI48_15910	ENOG4108M3R	transcriptional activator CadC
EFI48_15915	ENOG4105DVH	amino acid
EFI48_15920	ENOG4105EXG	Transcriptional regulator
EFI48_15940	ENOG4105C44	Serine transporter
EFI48_15945	ENOG4105EQ2	LysR family Transcriptional regulator
EFI48_15955	ENOG4105C7K	acetolactate synthase
EFI48_15970	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
EFI48_15975	ENOG4105DR5	peptidase
EFI48_15980	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
EFI48_16005	ENOG4105TMR	Functions as a holding molecular chaperone (holdase) which stabilizes unfolding intermediates and rapidly releases them in an active form once stress has abated. Plays an important role in protecting cells from severe heat shock and starvation, as well as in acid resistance of stationary-phase cells. It catalyzes the conversion of methylglyoxal (MG) to D-lactate in a single glutathione (GSH)-independent step (By similarity)
EFI48_16010	ENOG4106KR7	LysR family Transcriptional regulator
EFI48_16025	ENOG4105CV1	Transketolase (EC 2.2.1.1)
EFI48_16030	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
EFI48_16035	ENOG4105GPY	SprT protein
EFI48_16045	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
EFI48_16050	ENOG4105D7Z	glutathione synthase
EFI48_16060	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
EFI48_16080	ENOG410600T	transposase
EFI48_16085	ENOG4105G2Y	Transcriptional regulator
EFI48_16090	ENOG4105CNH	Multidrug resistance protein MdtL
EFI48_16095	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
EFI48_16105	ENOG4105F8C	transglutaminase domain-containing protein
EFI48_16110	ENOG4105BZG	amino acid carrier protein
EFI48_16115	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
EFI48_16125	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
EFI48_16130	ENOG4105C0B	DNA polymerase III (alpha subunit)
EFI48_16135	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
EFI48_16140	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EFI48_16145	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EFI48_16150	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
EFI48_16155	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
EFI48_16160	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
EFI48_16165	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EFI48_16170	ENOG4105DZP	Membrane-associated zinc metalloprotease
EFI48_16175	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
EFI48_16180	ENOG4105KNE	Phosphatidate cytidylyltransferase
EFI48_16185	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
EFI48_16190	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
EFI48_16195	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
EFI48_16200	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
EFI48_16205	ENOG4105CE9	30S ribosomal protein S2
EFI48_16210	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
EFI48_16215	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
EFI48_16220	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
EFI48_16225	ENOG4108T8E	UPF0325 protein
EFI48_16230	ENOG4105CI1	PTS System
EFI48_16235	ENOG4107W52	maltose operon periplasmic protein
EFI48_16240	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
EFI48_16245	ENOG4105QDK	Flavodoxin
EFI48_16250	ENOG4105DR9	pseudouridine synthase
EFI48_16255	ENOG4105WP7	tRNA pseudouridine synthase C
EFI48_16280	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
EFI48_16285	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
EFI48_16290	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
EFI48_16300	ENOG4105BZU	Histidine kinase
EFI48_16305	ENOG4105EWT	decarboxylase family
EFI48_16310	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
EFI48_16315	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EFI48_16325	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
EFI48_16330	ENOG4105M08	Membrane
EFI48_16340	ENOG4105ETT	transcriptional Regulator, LysR family
EFI48_16345	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_16350	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EFI48_16360	ENOG4107S0N	DJ-1 family
EFI48_16365	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
EFI48_16370	ENOG4108VPT	UPF0234 protein
EFI48_16380	ENOG4105EYM	Major Facilitator superfamily
EFI48_16385	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
EFI48_16395	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EFI48_16400	ENOG4105M85	Bola protein
EFI48_16405	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EFI48_16410	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EFI48_16415	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EFI48_16420	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EFI48_16425	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
EFI48_16430	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
EFI48_16435	ENOG4105CJ2	(LipO)protein
EFI48_16465	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
EFI48_16480	ENOG4107FW0	short-chain dehydrogenase reductase
EFI48_16490	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
EFI48_16495	ENOG4108XDN	Transcriptional regulator
EFI48_16500	ENOG4107SEY	Conserved Protein
EFI48_16515	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
EFI48_16530	ENOG4105CQC	Prephenate dehydratase
EFI48_16560	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_16570	ENOG4105E1F	short-chain dehydrogenase reductase
EFI48_16595	ENOG4105CTD	carboxy-peptidase
EFI48_16635	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
EFI48_16640	ENOG4105CFP	Peptidase U32
EFI48_16645	ENOG4105N14	lysine exporter protein LysE YggA
EFI48_16655	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
EFI48_16660	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_16665	ENOG4108VYJ	response regulator receiver protein
EFI48_16675	ENOG4105CBS	Chea signal transduction histidine kinase
EFI48_16685	ENOG4108V3W	Chemotaxis protein, CheW
EFI48_16690	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_16695	ENOG4105BZU	Histidine kinase
EFI48_16700	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
EFI48_16705	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
EFI48_16710	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
EFI48_16715	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
EFI48_16720	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
EFI48_16725	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
EFI48_16730	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
EFI48_16735	ENOG4105CHV	Transcription elongation factor NusA
EFI48_16740	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
EFI48_16760	ENOG4105CP7	Triose-phosphate isomerase
EFI48_16765	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
EFI48_16770	ENOG4105EEI	dihydropteroate synthase
EFI48_16775	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
EFI48_16780	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
EFI48_16785	ENOG4105HBR	Rna-binding protein
EFI48_16795	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
EFI48_16800	ENOG4107XSU	flagellar motor protein motb
EFI48_16805	ENOG4105E14	MotA TolQ exbB proton channel
EFI48_16810	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
EFI48_16815	ENOG4105CTB	Polyprenyl synthetase
EFI48_16820	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
EFI48_16825	ENOG4105CGH	5'-nucleotidase
EFI48_16845	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EFI48_16850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
EFI48_16860	ENOG41069P5	Protein slyX homolog
EFI48_16870	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
EFI48_16880	ENOG4108JQ6	ABC transporter
EFI48_16885	ENOG4108ZAI	phosphatidylglycerophosphatase a
EFI48_16890	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
EFI48_16895	ENOG4107YIM	Involved in the transcription termination process (By similarity)
EFI48_16900	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
EFI48_16915	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
EFI48_16920	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
EFI48_16925	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
EFI48_16935	ENOG4105BZU	Histidine kinase
EFI48_16940	ENOG4108SV3	Tmao reductase system periplasmic protein tort
EFI48_16950	ENOG4106WF9	DNA-binding transcriptional regulator TorR
EFI48_16955	ENOG4105CUW	cytochrome C-TYPE protein
EFI48_16960	ENOG4108EM1	reductase
EFI48_16965	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
EFI48_16975	ENOG4105BZU	Histidine kinase
EFI48_16985	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
EFI48_16990	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
EFI48_16995	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
EFI48_17000	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
EFI48_17005	ENOG4105RG0	Membrane
EFI48_17010	ENOG4108IA2	Sodium pantothenate symporter
EFI48_17015	ENOG4105CI1	PTS System
EFI48_17020	ENOG4105HEI	LysR family (Transcriptional regulator
EFI48_17025	ENOG4105CIS	alcohol dehydrogenase
EFI48_17030	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
EFI48_17040	ENOG41069NU	Nitroreductase
EFI48_17045	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
EFI48_17050	ENOG4105D07	Signal peptide peptidase, SppA
EFI48_17055	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
EFI48_17070	ENOG4109015	Biopolymer transport protein exbD tolR
EFI48_17090	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EFI48_17095	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
EFI48_17100	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
EFI48_17115	ENOG4108JQ7	(ABC) transporter
EFI48_17125	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
EFI48_17135	ENOG4105G4C	Periplasmic ligand-binding sensor protein
EFI48_17145	ENOG4105E4C	Lytic transglycosylase catalytic
EFI48_17160	ENOG4105C5H	ABC transporter
EFI48_17170	ENOG4105C7N	Xanthine uracil vitamin C permease
EFI48_17175	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
EFI48_17180	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_17190	ENOG4105VEQ	Cold shock protein
EFI48_17230	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
EFI48_17235	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
EFI48_17240	ENOG4105DJ4	phosphatidylserine decarboxylase
EFI48_17245	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
EFI48_17260	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
EFI48_17275	ENOG4105V1F	Fermentation respiration switch protein
EFI48_17280	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
EFI48_17290	ENOG4105CIN	aminoacyl-histidine dipeptidase
EFI48_17295	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
EFI48_17300	ENOG4108S0S	Nucleotidyl transferase
EFI48_17305	ENOG4105EHM	Aminoglycoside phosphotransferase
EFI48_17310	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
EFI48_17315	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
EFI48_17320	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
EFI48_17325	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
EFI48_17330	ENOG4105NWN	ApaG protein
EFI48_17335	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
EFI48_17350	ENOG4105DEN	Luciferase family
EFI48_17360	ENOG4105DWD	nucleoside recognition domain protein
EFI48_17365	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EFI48_17370	ENOG4105K46	50S ribosomal protein l27
EFI48_17375	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
EFI48_17380	ENOG4105EAH	synthase
EFI48_17390	ENOG4105EPW	hflc protein
EFI48_17395	ENOG4107QJR	hflk protein
EFI48_17400	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
EFI48_17405	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
EFI48_17410	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
EFI48_17415	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EFI48_17420	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
EFI48_17425	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
EFI48_17430	ENOG4105K8N	protein family UPF0079, ATPase
EFI48_17435	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
EFI48_17440	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
EFI48_17455	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
EFI48_17460	ENOG4108UMI	ABC transporter, permease
EFI48_17465	ENOG4105D01	(LipO)protein
EFI48_17470	ENOG4105MDZ	Transcriptional activator rfaH
EFI48_17480	ENOG4105BZU	Histidine kinase
EFI48_17485	ENOG4105BZU	Histidine kinase
EFI48_17495	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
EFI48_17500	ENOG4105BZU	Histidine kinase
EFI48_17520	ENOG4108Q67	UPF0319 protein
EFI48_17525	ENOG4105EXG	Transcriptional regulator
EFI48_17535	ENOG4107QWK	SAICAR synthetase
EFI48_17540	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
EFI48_17545	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EFI48_17550	ENOG4105RH4	Glycine cleavage system transcriptional repressor
EFI48_17555	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EFI48_17560	ENOG4105XWI	UPF0304 protein
EFI48_17565	ENOG4105PQ6	UPF0208 membrane protein
EFI48_17570	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
EFI48_17575	ENOG4105C6K	Malic enzyme
EFI48_17580	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
EFI48_17585	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
EFI48_17590	ENOG4105DUX	Transporter
EFI48_17595	ENOG4105I93	response regulator
EFI48_17625	ENOG4107KET	secretion protein, HlyD family
EFI48_17635	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
EFI48_17640	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
EFI48_17685	ENOG4105DFP	Integrase
EFI48_17710	ENOG4107R11	Transcriptional regulator
EFI48_17715	ENOG4108NIW	Leucine export protein LeuE
EFI48_17720	ENOG4108ZP8	Acetolactate synthase small subunit
EFI48_17725	ENOG4105C7K	acetolactate synthase
EFI48_17750	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
EFI48_17755	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
EFI48_17760	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EFI48_17765	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
EFI48_17780	ENOG4105DP9	ABC transporter
EFI48_17785	ENOG4106SMU	thiamine transporter membrane protein
EFI48_17790	ENOG4107T0D	ABC, transporter
EFI48_17795	ENOG4108IAB	Phoh family
EFI48_17835	ENOG4105BZU	Histidine kinase
EFI48_17845	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
EFI48_17850	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
EFI48_17865	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
EFI48_17870	ENOG4108IJ0	Aspartate ammonia-lyase
EFI48_17875	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
EFI48_17880	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EFI48_17885	ENOG4105VCC	30S ribosomal protein S21
EFI48_17890	ENOG4105KTH	gatB Yqey
EFI48_17895	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
EFI48_17900	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
EFI48_17920	ENOG4105C12	Phosphoribosylglycinamide synthetase
EFI48_17925	ENOG4105DC1	bifunctional purine biosynthesis protein purh
EFI48_17935	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
EFI48_17940	ENOG4105CSA	Coproporphyrinogen iii oxidase
EFI48_17945	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
EFI48_17955	ENOG4105D9R	oxidoreductase
EFI48_17965	ENOG4105D9U	N-acetyltransferase
EFI48_17970	ENOG4108Z9I	-acetyltransferase
EFI48_17985	ENOG4105EV4	Multidrug resistance protein mdtH
EFI48_17990	ENOG4108MJ3	acetyltransferase
EFI48_18000	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
EFI48_18005	ENOG4105CHR	reductase
EFI48_18010	ENOG4105BZU	Histidine kinase
EFI48_18015	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
EFI48_18030	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
EFI48_18040	ENOG4108IQE	Amp-dependent synthetase and ligase
EFI48_18050	ENOG4105D9M	gamma-glutamylcysteine synthetase
EFI48_18060	ENOG4105W39	Membrane
EFI48_18065	ENOG4105DQ4	alcohol dehydrogenase
EFI48_18090	ENOG4105DP0	ferredoxin-NADP reductase
EFI48_18095	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
EFI48_18100	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
EFI48_18105	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
EFI48_18110	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
EFI48_18115	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EFI48_18125	ENOG4105K70	DNA-binding protein
EFI48_18130	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
EFI48_18140	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
EFI48_18155	ENOG4105EAC	phosphoserine phosphatase
EFI48_18165	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
EFI48_18170	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
EFI48_18175	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
EFI48_18180	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
EFI48_18190	ENOG4105D9N	nucleoside
EFI48_18195	ENOG4105EYA	deoxyribonuclease
EFI48_18200	ENOG4106855	Competence protein
EFI48_18210	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
EFI48_18220	ENOG4108YZA	Nitrogen regulatory protein pii
EFI48_18225	ENOG4105C4K	Nad synthetase
EFI48_18285	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
EFI48_18290	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
EFI48_18295	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
EFI48_18300	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
EFI48_18305	ENOG4105DTN	riboflavin biosynthesis protein ribF
EFI48_18310	ENOG4105CJR	Integral membrane protein (MviN
EFI48_18315	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
EFI48_18320	ENOG41080HT	Transcriptional regulator, arsr family
EFI48_18325	ENOG41063Z6	transcriptional regulator, lysR family
EFI48_18335	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EFI48_18340	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
EFI48_18345	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
EFI48_18350	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
EFI48_18355	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
EFI48_18360	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
EFI48_18370	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
EFI48_18375	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
EFI48_18380	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
EFI48_18385	ENOG4105K5M	30s ribosomal protein S16
EFI48_18390	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EFI48_18395	ENOG4106KVJ	cytochrome C assembly protein
EFI48_18400	ENOG4108JU6	CBS domain protein
EFI48_18410	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
EFI48_18415	ENOG4108UV7	flagellar protein motX
EFI48_18420	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
EFI48_18425	ENOG4105DMR	ABC, transporter
EFI48_18430	ENOG4105GBT	ABC transporter
EFI48_18435	ENOG4106PMH	Extracellular solute-binding protein family 3
EFI48_18440	ENOG4105E5Z	arginine transporter ATP-binding subunit
EFI48_18445	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
EFI48_18450	ENOG4105EZR	dyp-type peroxidase family protein
EFI48_18455	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
EFI48_18475	ENOG4108YZA	Nitrogen regulatory protein pii
EFI48_18480	ENOG4108YZN	class I peptide chain release factor
EFI48_18495	ENOG4105D1Q	UPF0246 protein
EFI48_18500	ENOG4105CZX	twitching motility protein
EFI48_18505	ENOG4105CZX	twitching motility protein
EFI48_18510	ENOG4105DFA	alanine racemase domain protein
EFI48_18515	ENOG4105II7	pyrroline-5-carboxylate reductase
EFI48_18520	ENOG4108VIA	integral membrane protein
EFI48_18525	ENOG4105VZ9	UPF0235 protein
EFI48_18535	ENOG4105D9N	nucleoside
EFI48_18540	ENOG4105HEI	LysR family (Transcriptional regulator
EFI48_18555	ENOG4105BZW	Glycerate kinase
EFI48_18560	ENOG4107QQ0	gntp family
EFI48_18565	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
EFI48_18570	ENOG4105XTV	UPF0231 protein
EFI48_18600	ENOG4105C1J	atp-dependent rna helicase
EFI48_18610	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
EFI48_18640	ENOG4105CGF	Aromatic amino acid aminotransferase
EFI48_18660	ENOG41076CZ	activating enzyme
EFI48_18665	ENOG4105G0K	glycine radical enzyme YjjI family
EFI48_18690	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
EFI48_18705	ENOG4105CND	Glycosyl transferase, family 2
EFI48_18710	ENOG4107BJW	polysaccharide deacetylase
EFI48_18725	ENOG4108N3W	hemolysin secretion protein
EFI48_18730	ENOG4108M1A	Chitin-binding protein
EFI48_18735	ENOG4107R11	Transcriptional regulator
EFI48_18740	ENOG4108IJ6	ABC transporter
EFI48_18745	ENOG4105ECW	sulfate abc transporter
EFI48_18750	ENOG4108I5D	sulfate abc transporter
EFI48_18760	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
EFI48_18765	ENOG4107PU6	Membrane
EFI48_18770	ENOG4108UW5	maltose o-acetyltransferase
EFI48_18785	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
EFI48_18790	ENOG4107RK2	ADP-ribose diphosphatase NudE
EFI48_18795	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
EFI48_18800	ENOG4105C44	Serine transporter
EFI48_18805	ENOG4108Z7R	Chaperone CsaA
EFI48_18815	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
EFI48_18820	ENOG4105C28	cystathionine
EFI48_18825	ENOG4105CFH	Aspartokinase
EFI48_18830	ENOG4105CJ3	phosphate transporter
EFI48_18835	ENOG4107IX6	phosphate transport regulator
EFI48_18845	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
EFI48_18850	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
EFI48_18855	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
EFI48_18860	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
EFI48_18900	ENOG4105DFD	Na H antiporter
EFI48_18905	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
EFI48_18915	ENOG4105CMQ	Chloride channel
EFI48_18920	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
EFI48_18935	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
EFI48_18970	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
EFI48_18975	ENOG4105D3G	Pseudouridine synthase
EFI48_18990	ENOG4108UW5	maltose o-acetyltransferase
EFI48_18995	ENOG4105CG3	alpha amylase, catalytic region
EFI48_19000	ENOG4105C5Y	PTS System
EFI48_19005	ENOG4105D4X	repressor
EFI48_19020	ENOG4105HDK	L-asparaginase
EFI48_19030	ENOG4106W5V	Membrane
EFI48_19035	ENOG41061WM	D-Alanyl-D-Alanine
EFI48_19070	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
EFI48_19075	ENOG4105CFH	Aspartokinase
EFI48_19080	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
EFI48_19090	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
EFI48_19095	ENOG4107TH8	cina domain protein
EFI48_19105	ENOG4108NF7	phage-type endonuclease
EFI48_19150	ENOG4105W5Q	DNA repair protein (RadC
EFI48_19175	ENOG4108NRW	Phospholipase, patatin family
EFI48_19180	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
EFI48_19185	ENOG4105DFP	Integrase
EFI48_19205	ENOG4107R3N	Filamentation induced by cAMP protein fic
EFI48_19210	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
EFI48_19255	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EFI48_19295	ENOG41067MG	lrgb family
EFI48_19300	ENOG4105VAW	lrga family
EFI48_19305	ENOG4105CMU	LysR family (Transcriptional regulator
EFI48_19325	ENOG4108Z66	YbaK ebsC protein
EFI48_19345	ENOG4105M03	Domain of unknown function (DUF955)
EFI48_19355	ENOG4105D41	biosynthesis protein thiH
EFI48_19360	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
EFI48_19370	ENOG4105D06	uba thif-type nad fad binding protein
EFI48_19375	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
EFI48_19380	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
EFI48_19400	ENOG4105ETX	regulatoR
EFI48_19410	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
EFI48_19415	ENOG4105C3R	Methionine synthase
EFI48_19420	ENOG4105EEQ	Na H antiporter
EFI48_19460	ENOG4105CSH	Transporter
EFI48_19475	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
EFI48_19490	ENOG4105QD6	exported protein
EFI48_19495	ENOG4105C03	ribonuclease
EFI48_19500	ENOG4108Z03	MAF-like protein
EFI48_19505	ENOG4105VQ7	Rod shape-determining protein MreD
EFI48_19510	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
EFI48_19515	ENOG4105DFF	Rod shape-determining protein mreb
EFI48_19540	ENOG4106855	Competence protein
EFI48_19560	ENOG4105D7Q	type ii secretion system
EFI48_19565	ENOG4107QHF	type ii secretion system protein e
EFI48_19580	ENOG4105GVR	general secretion pathway protein D
EFI48_19610	ENOG41062P1	Diguanylate cyclase phosphodiesterase
EFI48_19615	ENOG4105CXC	rtn protein
EFI48_19620	ENOG4105EWV	Sodium calcium exchanger membrane region
EFI48_19625	ENOG4105C84	Histidine ammonia-lyase
EFI48_19630	ENOG4105CGP	Urocanate hydratase
EFI48_19635	ENOG41088SP	formiminoglutamate hydrolase
EFI48_19640	ENOG4105CI2	imidazolone-5-propionate hydrolase
EFI48_19645	ENOG4105CZE	histidine utilization repressor
EFI48_19650	ENOG41077A9	carbonic anhydrase
EFI48_19660	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
EFI48_19665	ENOG4105CAK	Cell division ATP-binding protein ftsE
EFI48_19670	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EFI48_19675	ENOG4106H78	methyltransferase
EFI48_19700	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
EFI48_19705	ENOG4108W5M	transcriptional regulator
EFI48_19710	ENOG4105EMU	Dehydrogenase
EFI48_19725	ENOG4105CUG	Oligopeptidase b
EFI48_19740	ENOG4107RZC	phospholipase d
EFI48_19745	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
EFI48_19765	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
EFI48_19770	ENOG4105VVZ	metal-binding protein
EFI48_19785	ENOG4105JQN	Transcriptional regulator
EFI48_19800	ENOG4107FS9	Membrane
EFI48_19815	ENOG4105EJ2	Transcriptional regulator
EFI48_19850	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
EFI48_19855	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EFI48_19860	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
EFI48_19865	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
EFI48_19870	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
EFI48_19875	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
EFI48_19885	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
EFI48_19890	ENOG4105KME	endoribonuclease L-psp
EFI48_19895	ENOG4105WWK	YheO domain protein
EFI48_19900	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EFI48_19905	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
EFI48_19910	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
EFI48_19915	ENOG4108VZM	50s ribosomal protein L10
EFI48_19920	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
EFI48_19925	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
EFI48_19930	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
EFI48_19935	ENOG4105PM1	preprotein translocase subunit SecE
EFI48_19945	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
EFI48_19965	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
EFI48_19970	ENOG4105D4A	Cell wall formation (By similarity)
EFI48_19975	ENOG4107ZYR	domain protein
EFI48_20000	ENOG4108IYH	Dna topoisomerase
EFI48_20010	ENOG4105BZU	Histidine kinase
EFI48_20015	ENOG4105CUW	cytochrome C-TYPE protein
EFI48_20020	ENOG4107QY8	reductase
EFI48_20030	ENOG4105IFJ	Histidine kinase
EFI48_20035	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
EFI48_20065	ENOG4108UQ5	membrane protein YcdZ
EFI48_20070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EFI48_20080	ENOG4107WP9	Histidine kinase
EFI48_20095	ENOG410642E	Short chain dehydrogenase
EFI48_20100	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
EFI48_20115	ENOG4108VVK	transcriptional Regulator, AsnC
EFI48_20120	ENOG4105CU9	asparagine synthetase A
EFI48_20125	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
EFI48_20130	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
EFI48_20135	ENOG4105C34	Pseudouridine synthase
EFI48_20140	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EFI48_20145	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
EFI48_20155	ENOG4105CEM	UPF0597 protein
EFI48_20160	ENOG4105WWK	YheO domain protein
EFI48_20170	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EFI48_20175	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
EFI48_20180	ENOG4108I6A	alcohol dehydrogenase
EFI48_20185	ENOG4105CF7	AraC family transcriptional regulator
EFI48_20195	ENOG4105C8Q	Methyl-accepting chemotaxis
EFI48_20205	ENOG4105DUM	transcriptional regulator, lysR family
EFI48_20220	ENOG4105CXT	aspartate transcarbamylase
EFI48_20225	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
EFI48_20230	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
EFI48_20235	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
EFI48_20240	ENOG4105DBV	ornithine carbamoyltransferase
EFI48_20245	ENOG4105C5B	carbamate kinase
EFI48_20265	ENOG4105D4P	Coproporphyrinogen iii oxidase
EFI48_20270	ENOG4105XCT	Protein of unknown function (DUF2489)
EFI48_20275	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
EFI48_20285	ENOG4106RE7	Cytochrome
EFI48_20290	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
EFI48_20300	ENOG4105E2X	shikimate dehydrogenase
EFI48_20305	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
EFI48_20310	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
EFI48_20320	ENOG4108WI1	Dna topoisomerase
EFI48_20325	ENOG4108RPN	Protein smg homolog
EFI48_20330	ENOG4105C79	DNA protecting protein DprA
EFI48_20335	ENOG4108WZM	domain protein
EFI48_20340	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
EFI48_20345	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
EFI48_20350	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
EFI48_20355	ENOG4105C1A	potassium transporter peripheral membrane
EFI48_20360	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
EFI48_20370	ENOG4105C5F	glutamine synthetase
EFI48_20380	ENOG4105CUX	Signal transduction histidine kinase
EFI48_20385	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
EFI48_20390	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
EFI48_20395	ENOG4105CGY	Dna recombination protein
EFI48_20415	ENOG4108TFM	Kinase, PfkB family
EFI48_20420	ENOG4107R11	Transcriptional regulator
EFI48_20425	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
EFI48_20430	ENOG4105C26	Dehydrogenase
EFI48_20440	ENOG4108JCI	Transcriptional regulator
EFI48_20445	ENOG4105C26	Dehydrogenase
EFI48_20455	ENOG4105FR1	rard protein
EFI48_20460	ENOG4108N3W	hemolysin secretion protein
EFI48_20465	ENOG4105CUC	YeeE YedE family protein
EFI48_20470	ENOG4105UYK	outer membrane protein a
EFI48_20475	ENOG4105C7B	Threonine dehydratase
EFI48_20480	ENOG4105C01	Dihydroxy-acid dehydratase
EFI48_20485	ENOG4105CM2	brancheD-chain amino acid aminotransferase
EFI48_20490	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
EFI48_20505	ENOG4105C0P	Mg chelatase subunit ChlI
EFI48_20510	ENOG4106HNH	Acyl-transferase
EFI48_20515	ENOG4106HNH	Acyl-transferase
EFI48_20520	ENOG4105EWC	Purine nucleoside phosphorylase
EFI48_20530	ENOG4108RWI	nicotinamidase
EFI48_20535	ENOG4107RH7	Nicotinate phosphoribosyltransferase
EFI48_20540	ENOG4108Z33	Thiol disulfide Interchange Protein
EFI48_20545	ENOG4105E27	serine threonine protein kinase
EFI48_20555	ENOG4105PC1	Conserved Protein
EFI48_20565	ENOG4108Z6Z	Transcriptional regulator
EFI48_20570	ENOG4105C59	p-type ATPase
EFI48_20575	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
EFI48_20580	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
EFI48_20585	ENOG4105DSJ	YicC domain protein
EFI48_20615	ENOG4106H3A	restriction
EFI48_20625	ENOG4105CVR	type I restriction-modification system
EFI48_20630	ENOG41082EK	Restriction modification system DNA (Specificity
EFI48_20635	ENOG410600T	transposase
EFI48_20670	ENOG4105CC0	LysR family Transcriptional regulator
EFI48_20680	ENOG4105C4W	S-formylglutathione hydrolase
EFI48_20690	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
EFI48_20695	ENOG4105DHU	Bile acid
EFI48_20700	ENOG4105E5D	amino acid
EFI48_20705	ENOG4108Y51	tRNA-binding protein
EFI48_20710	ENOG4105E5D	amino acid
EFI48_20715	ENOG4105FK9	beta-D-galactosidase beta subunit
EFI48_20720	ENOG4105CNT	hydrolase family 2
EFI48_20725	ENOG4105CQ4	Transcriptional regulator
EFI48_20760	ENOG4108Z0R	Transferase
EFI48_20765	ENOG4105C2M	dna polymerase I
EFI48_20775	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
EFI48_20780	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
EFI48_20790	ENOG4105D7W	serine acetyltransferase
EFI48_20800	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
EFI48_20805	ENOG4105E0F	Histidine kinase
EFI48_20810	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
EFI48_20815	ENOG4107R73	Mate efflux family protein
EFI48_20830	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
EFI48_20835	ENOG4105E55	glycerol-3-phosphate acyltransferase
EFI48_20840	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
EFI48_20845	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
EFI48_20870	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
EFI48_20875	ENOG4105DIQ	Transcriptional regulator
EFI48_20880	ENOG4106ETB	IIa component
EFI48_20895	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
EFI48_20900	ENOG4105XA0	heptosyltransferase ii
EFI48_20905	ENOG4106WTF	Glycosyl transferase, family 2
EFI48_20910	ENOG4105M5K	heptosyltransferase
EFI48_20915	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
EFI48_20920	ENOG4108MJ5	VirK protein
EFI48_20925	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
EFI48_20935	ENOG4105W0E	50S ribosomal protein L33
EFI48_20940	ENOG4105KDC	50s ribosomal protein l28
EFI48_20945	ENOG4105W5Q	DNA repair protein (RadC
EFI48_20950	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
EFI48_20955	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
EFI48_20960	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
EFI48_20965	ENOG4105D64	Mechanosensitive ion channel
EFI48_20970	ENOG4107QP8	phosphohexose isomerase
EFI48_20975	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
EFI48_20980	ENOG4105EMY	transcriptional regulator
EFI48_20995	ENOG4105CD5	CoA-binding domain protein
EFI48_21035	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
EFI48_21040	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
EFI48_21045	ENOG41063Z6	transcriptional regulator, lysR family
EFI48_21060	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
EFI48_21065	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
EFI48_21070	ENOG4105FCD	Major Facilitator
EFI48_21075	ENOG4105DY9	regulatoR
EFI48_21080	ENOG4108HRK	Histidine kinase
EFI48_21085	ENOG4105CBX	hi0933 family
EFI48_21090	ENOG41090A1	ferritin
EFI48_21095	ENOG4105RKW	reductase (By
EFI48_21105	ENOG4108M6U	Universal stress protein A
EFI48_21135	ENOG4105EMK	carboxylate amino acid amine transporter
EFI48_21145	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
EFI48_21150	ENOG4105DKP	glycosyl transferase, family 9
EFI48_21160	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
EFI48_21165	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
EFI48_21170	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
EFI48_21175	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
EFI48_21185	ENOG4108EUD	Lysophospholipase
EFI48_21190	ENOG4105DQF	Hydrolase
EFI48_21220	ENOG4105Y7M	Transcriptional regulator, TetR family
EFI48_21225	ENOG410624X	efflux transporter, rnd family, mfp subunit
EFI48_21230	ENOG4105BZS	acriflavin resistance protein
EFI48_21235	ENOG4105BZU	Histidine kinase
EFI48_21240	ENOG4105DC8	reductase
EFI48_21250	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EFI48_21255	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
EFI48_21265	ENOG4105C08	Histidine kinase
EFI48_21270	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
EFI48_21275	ENOG4105C2C	drug resistance transporter, Bcr CflA
EFI48_21290	ENOG4105JKW	Valine--pyruvate aminotransferase
EFI48_21295	ENOG4108ZNX	Heat shock protein
EFI48_21300	ENOG4108ZNX	Heat shock protein
EFI48_21305	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
EFI48_21310	ENOG4105ECQ	AraC Family Transcriptional Regulator
EFI48_21315	ENOG4105D29	Helix-turn-helix type 11 domain protein
EFI48_21320	ENOG4108EF6	Proline imino-peptidase
EFI48_21330	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
EFI48_21335	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
EFI48_21340	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
EFI48_21345	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
EFI48_21350	ENOG4105EAB	amino acid AbC transporter
EFI48_21355	ENOG4105E5Q	amino acid AbC transporter
EFI48_21360	ENOG4105CDA	abc transporter atp-binding protein
EFI48_21365	ENOG4105VG0	50S ribosomal protein l34
EFI48_21370	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
EFI48_21375	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
EFI48_21380	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EFI48_21385	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
EFI48_21390	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
EFI48_21570	ENOG4105CAF	HipA N-terminal domain protein
EFI48_21575	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
EFI48_21580	ENOG4105J76	Periplasmic binding protein
EFI48_21585	ENOG4105E0A	ABC, transporter
EFI48_21590	ENOG4105IBP	Cyclic peptide transporter
EFI48_21595	ENOG4105E0K	tonB-dependent siderophore receptor
EFI48_21600	ENOG4105QTB	Flavodoxin
EFI48_21605	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
EFI48_21610	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
EFI48_21615	ENOG4107QJE	Chromosome Partitioning Protein
EFI48_21620	ENOG4105FA0	parb-like partition protein
EFI48_21630	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
EFI48_21635	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EFI48_21640	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
EFI48_21645	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)