locus-tag	class	description
AMS64_00020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMS64_00025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMS64_00030	COG1561	YicC-like family, N-terminal region
AMS64_00035	COG0583	DNA-binding transcription factor activity
AMS64_00055	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMS64_00060	COG0385	Bile acid
AMS64_00065	COG0531	amino acid
AMS64_00070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_00075	COG0531	amino acid
AMS64_00080	COG2731	YhcH YjgK YiaL family protein
AMS64_00085	COG3250	beta-galactosidase activity
AMS64_00090	COG1609	Transcriptional regulator
AMS64_00150	COG0583	DNA-binding transcription factor activity
AMS64_00165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AMS64_00170	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AMS64_00175	COG2223	nitrite transmembrane transporter activity
AMS64_00180	COG3279	Response regulator of the LytR AlgR family
AMS64_00185	COG3275	phosphorelay sensor kinase activity
AMS64_00190	COG2081	HI0933 family
AMS64_00195	COG1528	Iron-storage protein
AMS64_00200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMS64_00205	COG0589	response to stress
AMS64_00240	COG3642	lipopolysaccharide core region biosynthetic process
AMS64_00245	COG0859	PFAM glycosyl transferase family 9
AMS64_00255	COG0194	GDP metabolic process
AMS64_00260	COG1758	RNA polymerase activity
AMS64_00265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMS64_00270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMS64_00280	COG2267	carboxylic ester hydrolase activity
AMS64_00285	COG0561	phosphatase activity
AMS64_00315	COG1309	transcriptional regulator
AMS64_00320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_00325	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_00330	COG4191	Histidine kinase
AMS64_00335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMS64_00355	COG2205	protein histidine kinase activity
AMS64_00360	COG0745	RESPONSE REGULATOR receiver
AMS64_00365	COG2814	Major facilitator Superfamily
AMS64_00375	COG3977	Valine--pyruvate aminotransferase
AMS64_00380	COG0071	Belongs to the small heat shock protein (HSP20) family
AMS64_00385	COG0071	Belongs to the small heat shock protein (HSP20) family
AMS64_00390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMS64_00400	COG2378	regulation of single-species biofilm formation
AMS64_00415	COG0187	DNA topoisomerase II activity
AMS64_00425	COG0592	DNA-directed DNA polymerase activity
AMS64_00430	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMS64_00450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AMS64_00455	COG0594	ribonuclease P activity
AMS64_00460	COG0706	membrane insertase activity
AMS64_00465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AMS64_00475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMS64_00480	COG1120	ATPase activity
AMS64_00485	COG4615	Cyclic peptide transporter
AMS64_00490	COG4774	siderophore transport
AMS64_00495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMS64_00500	COG0445	tRNA wobble uridine modification
AMS64_00505	COG0357	Ribosomal RNA small subunit methyltransferase G
AMS64_00510	COG1192	Involved in chromosome partitioning
AMS64_00515	COG1475	DNA binding
AMS64_00525	COG0356	it plays a direct role in the translocation of protons across the membrane
AMS64_00535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMS64_00540	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMS64_00545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMS64_00550	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMS64_00555	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMS64_00560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMS64_00565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMS64_00570	COG4452	Inner membrane protein CreD
AMS64_00585	COG2205	protein histidine kinase activity
AMS64_00590	COG0745	RESPONSE REGULATOR receiver
AMS64_00595	COG1349	DNA-binding transcription factor activity
AMS64_00600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMS64_00605	COG2771	luxR family
AMS64_00615	COG0811	peptide transport
AMS64_00620	COG0811	peptide transport
AMS64_00625	COG0848	biopolymer transport protein
AMS64_00630	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AMS64_00665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AMS64_00670	COG0402	S-adenosylhomocysteine deaminase activity
AMS64_00675	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMS64_00680	COG2226	methyltransferase
AMS64_00685	COG3165	ubiquinone biosynthetic process from chorismate
AMS64_00690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMS64_00695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMS64_00700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMS64_00705	COG0805	protein transport
AMS64_00710	COG0084	hydrolase, TatD family'
AMS64_00720	COG3397	chitin binding
AMS64_00725	COG3469	chitinase activity
AMS64_00750	COG0742	ribosomal rna small subunit methyltransferase
AMS64_00760	COG0248	Ppx GppA phosphatase
AMS64_00765	COG0513	Belongs to the DEAD box helicase family
AMS64_00770	COG3118	belongs to the thioredoxin family
AMS64_00775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMS64_00785	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AMS64_00795	COG5001	Diguanylate cyclase
AMS64_00800	COG2960	long-chain fatty acid transporting porin activity
AMS64_00815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMS64_00835	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMS64_00845	COG1609	Transcriptional regulator
AMS64_00880	COG0751	glycine-tRNA ligase activity
AMS64_00885	COG0752	glycyl-tRNA synthetase alpha subunit
AMS64_00890	COG2818	Glycosylase
AMS64_00895	COG2885	chlorophyll binding
AMS64_00900	COG0251	oxidation-reduction process
AMS64_00905	COG0425	Belongs to the sulfur carrier protein TusA family
AMS64_00920	COG2205	protein histidine kinase activity
AMS64_00925	COG0745	RESPONSE REGULATOR receiver
AMS64_00930	COG0183	Belongs to the thiolase family
AMS64_00935	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMS64_00935	COG1024	Enoyl-CoA hydratase
AMS64_00940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMS64_00945	COG0006	proline dipeptidase activity
AMS64_00950	COG1739	Uncharacterized protein family UPF0029
AMS64_00955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMS64_00960	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
AMS64_00990	COG1042	CoA-binding domain protein
AMS64_00990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMS64_00990	COG0045	succinate-CoA ligase (ADP-forming) activity
AMS64_01005	COG0583	DNA-binding transcription factor activity
AMS64_01010	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMS64_01015	COG0166	Belongs to the GPI family
AMS64_01020	COG0668	transmembrane transport
AMS64_01025	COG1309	transcriptional regulator
AMS64_01035	COG0756	dUTP diphosphatase activity
AMS64_01080	COG2916	Histone family protein nucleoid-structuring protein H-NS
AMS64_01115	COG0210	DNA helicase
AMS64_01140	COG4974	Belongs to the 'phage' integrase family
AMS64_01150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMS64_01155	COG2003	Belongs to the UPF0758 family
AMS64_01160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMS64_01165	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMS64_01175	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMS64_01180	COG2990	Protein conserved in bacteria
AMS64_01185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMS64_01190	COG0859	PFAM glycosyl transferase family 9
AMS64_01195	COG0463	Glycosyl transferase, family 2
AMS64_01200	COG0859	PFAM glycosyl transferase family 9
AMS64_01205	COG1519	Transferase
AMS64_01210	COG0604	alcohol dehydrogenase
AMS64_01225	COG3161	chorismate lyase activity
AMS64_01230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMS64_01235	COG2937	Belongs to the GPAT DAPAT family
AMS64_01240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMS64_01255	COG0534	Mate efflux family protein
AMS64_01260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMS64_01265	COG2205	protein histidine kinase activity
AMS64_01270	COG0745	RESPONSE REGULATOR receiver
AMS64_01280	COG1045	serine acetyltransferase
AMS64_01290	COG3074	FtsZ-dependent cytokinesis
AMS64_01295	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AMS64_01305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMS64_01330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMS64_01335	COG2166	iron-sulfur cluster assembly
AMS64_01340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMS64_01355	COG3245	cytochrome
AMS64_01360	COG1063	alcohol dehydrogenase
AMS64_01375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMS64_01390	COG3307	-O-antigen
AMS64_01395	COG3306	glycosyltransferase involved in LPS biosynthesis
AMS64_01430	COG1280	lysine exporter protein (LysE YggA)
AMS64_01475	COG0210	DNA helicase
AMS64_01500	COG0737	Belongs to the 5'-nucleotidase family
AMS64_01510	COG2239	Acts as a magnesium transporter
AMS64_01515	COG1648	precorrin-2 dehydrogenase activity
AMS64_01515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMS64_01520	COG2116	formate transmembrane transporter activity
AMS64_01525	COG2146	nitrite reductase [NAD(P)H] activity
AMS64_01530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMS64_01535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMS64_01540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMS64_01550	COG0018	arginyl-trna synthetase
AMS64_01560	COG1595	DNA-templated transcription, initiation
AMS64_01570	COG1968	undecaprenyl-diphosphatase activity
AMS64_01575	COG2017	converts alpha-aldose to the beta-anomer
AMS64_01580	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMS64_01585	COG1085	galactose-1-phosphate uridylyltransferase
AMS64_01590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMS64_01595	COG1609	Transcriptional regulator
AMS64_01600	COG3250	beta-galactosidase activity
AMS64_01610	COG1129	ABC transporter
AMS64_01615	COG4211	Belongs to the binding-protein-dependent transport system permease family
AMS64_01625	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMS64_01640	COG0366	Alpha amylase catalytic
AMS64_01655	COG0443	Heat shock 70 kDa protein
AMS64_01660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMS64_01665	COG3045	CreA protein
AMS64_01680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMS64_01685	COG0174	glutamine synthetase
AMS64_01705	COG3842	ATPase activity
AMS64_01710	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMS64_01715	COG1177	transmembrane transport
AMS64_01720	COG2258	MOSC domain
AMS64_01735	COG2050	protein possibly involved in aromatic compounds catabolism
AMS64_01740	COG0514	ATP-dependent DNA helicase (RecQ)
AMS64_01750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AMS64_01760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AMS64_01765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMS64_01780	COG0254	rRNA binding
AMS64_01785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMS64_01795	COG0702	epimerase
AMS64_01800	COG0814	amino acid
AMS64_01805	COG0281	malic enzyme
AMS64_01810	COG1295	ribonuclease BN
AMS64_01815	COG1490	D-aminoacyl-tRNA deacylase activity
AMS64_01820	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AMS64_01825	COG0456	acetyltransferase
AMS64_01835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMS64_01840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMS64_01845	COG2610	gluconate transmembrane transporter activity
AMS64_01850	COG3265	gluconokinase activity
AMS64_01855	COG0129	dihydroxy-acid dehydratase activity
AMS64_01860	COG0800	Aldolase
AMS64_01865	COG1609	Transcriptional regulator
AMS64_01875	COG4942	peptidase
AMS64_01880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AMS64_01885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMS64_01890	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AMS64_01895	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMS64_01900	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AMS64_01900	COG0316	Belongs to the HesB IscA family
AMS64_01905	COG1040	competence protein
AMS64_01910	COG0596	Alpha beta hydrolase
AMS64_01930	COG2183	response to ionizing radiation
AMS64_01935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMS64_01940	COG0745	RESPONSE REGULATOR receiver
AMS64_01955	COG0051	transcription antitermination factor activity, RNA binding
AMS64_01960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMS64_01965	COG0088	Forms part of the polypeptide exit tunnel
AMS64_01970	COG0089	rRNA binding
AMS64_01975	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMS64_01980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMS64_01985	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMS64_01990	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMS64_01995	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMS64_02000	COG0255	Belongs to the universal ribosomal protein uL29 family
AMS64_02005	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMS64_02010	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMS64_02015	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMS64_02020	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMS64_02025	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMS64_02030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMS64_02035	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMS64_02040	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMS64_02045	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMS64_02050	COG1841	ribosomal large subunit assembly
AMS64_02055	COG0200	Binds to the 23S rRNA
AMS64_02060	COG0201	protein transport
AMS64_02065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AMS64_02070	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMS64_02075	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMS64_02080	COG0202	RNA polymerase activity
AMS64_02085	COG0203	ribosomal protein L17
AMS64_02115	COG4771	TonB-dependent receptor
AMS64_02120	COG3706	GGDEF domain
AMS64_02130	COG0745	RESPONSE REGULATOR receiver
AMS64_02145	COG0583	DNA-binding transcription factor activity
AMS64_02155	COG1741	Belongs to the pirin family
AMS64_02160	COG2259	Doxx family
AMS64_02165	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AMS64_02170	COG1074	ATP-dependent DNA helicase activity
AMS64_02175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMS64_02215	COG1175	transmembrane transport
AMS64_02225	COG3842	ATPase activity
AMS64_02255	COG2873	o-acetylhomoserine
AMS64_02260	COG4533	DNA binding
AMS64_02265	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMS64_02280	COG5380	lipid catabolic process
AMS64_02285	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMS64_02290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMS64_02315	COG0753	catalase activity
AMS64_02320	COG1247	-acetyltransferase
AMS64_02350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMS64_02355	COG0795	lipopolysaccharide-transporting ATPase activity
AMS64_02360	COG0795	lipopolysaccharide-transporting ATPase activity
AMS64_02505	COG4695	Portal protein
AMS64_02595	COG0582	viral genome integration into host DNA
AMS64_02645	COG0531	amino acid
AMS64_02665	COG1494	fructose-1,6-bisphosphatase
AMS64_02680	COG2959	enzyme of heme biosynthesis
AMS64_02690	COG0181	hydroxymethylbilane synthase activity
AMS64_02695	COG3072	Adenylate cyclase
AMS64_02700	COG0400	carboxylic ester hydrolase activity
AMS64_02705	COG1965	Belongs to the frataxin family
AMS64_02710	COG0019	diaminopimelate decarboxylase activity
AMS64_02715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMS64_02730	COG1011	Hydrolase
AMS64_02750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMS64_02755	COG3028	Belongs to the UPF0307 family
AMS64_02760	COG0312	modulator of DNA gyrase
AMS64_02765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMS64_02770	COG5007	Belongs to the BolA IbaG family
AMS64_02780	COG2854	intermembrane phospholipid transfer
AMS64_02785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMS64_02790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMS64_02795	COG1127	ABC transporter
AMS64_02800	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AMS64_02800	COG0517	IMP dehydrogenase activity
AMS64_02805	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMS64_02810	COG3117	lipopolysaccharide transmembrane transporter activity
AMS64_02815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AMS64_02820	COG1137	ATPase activity
AMS64_02835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_02840	COG1660	Displays ATPase and GTPase activities
AMS64_02845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_02850	COG3711	transcriptional antiterminator
AMS64_02850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_02865	COG3964	amidohydrolase
AMS64_02895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMS64_02900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMS64_02910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AMS64_02915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMS64_02920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMS64_02925	COG0723	plastoquinol--plastocyanin reductase activity
AMS64_02930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMS64_02935	COG2857	Cytochrome c1
AMS64_02940	COG0625	glutathione transferase activity
AMS64_02945	COG2969	positive regulation of protein catabolic process
AMS64_02950	COG2823	Periplasmic or secreted lipoprotein
AMS64_02955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMS64_02960	COG0792	nuclease activity
AMS64_02965	COG3107	peptidoglycan biosynthetic process
AMS64_02970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AMS64_03015	COG1987	bacterial-type flagellum assembly
AMS64_03035	COG2204	response regulator
AMS64_03040	COG1677	Flagellar hook-basal body complex protein FliE
AMS64_03050	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMS64_03085	COG1815	bacterial-type flagellum-dependent cell motility
AMS64_03090	COG1558	bacterial-type flagellum-dependent cell motility
AMS64_03095	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AMS64_03100	COG1749	Flagellar hook protein flgE
AMS64_03105	COG4787	bacterial-type flagellum-dependent cell motility
AMS64_03110	COG4786	Flagellar basal body rod
AMS64_03115	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMS64_03120	COG1706	bacterial-type flagellum-dependent cell motility
AMS64_03130	COG1256	bacterial-type flagellum assembly
AMS64_03130	COG4786	Flagellar basal body rod
AMS64_03135	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMS64_03150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMS64_03155	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AMS64_03180	COG1191	sigma factor activity
AMS64_03185	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_03195	COG0741	lytic transglycosylase activity
AMS64_03195	COG1388	LysM domain
AMS64_03205	COG2001	Belongs to the MraZ family
AMS64_03210	COG0275	rRNA processing
AMS64_03215	COG3116	cell division
AMS64_03220	COG0768	penicillin binding
AMS64_03230	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMS64_03235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMS64_03240	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMS64_03245	COG0772	Belongs to the SEDS family
AMS64_03250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMS64_03255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMS64_03265	COG0849	cell division
AMS64_03270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMS64_03275	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMS64_03285	COG0653	protein targeting
AMS64_03290	COG0494	nUDIX hydrolase
AMS64_03295	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AMS64_03300	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AMS64_03315	COG1459	type II secretion system
AMS64_03320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMS64_03345	COG2186	Transcriptional regulator
AMS64_03350	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMS64_03355	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMS64_03360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMS64_03370	COG0840	transmembrane signaling receptor activity
AMS64_03375	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMS64_03380	COG1049	propionate catabolic process, 2-methylcitrate cycle
AMS64_03395	COG0523	cobalamin synthesis protein
AMS64_03400	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_03415	COG0477	Major facilitator Superfamily
AMS64_03430	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AMS64_03435	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMS64_03485	COG0165	Argininosuccinate lyase
AMS64_03490	COG0137	argininosuccinate synthase activity
AMS64_03500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMS64_03505	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMS64_03515	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AMS64_03520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMS64_03535	COG0583	DNA-binding transcription factor activity
AMS64_03540	COG1380	Effector of murein hydrolase LrgA
AMS64_03545	COG1346	cytolysis
AMS64_03555	COG4667	esterase of the alpha-beta hydrolase superfamily
AMS64_03560	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMS64_03565	COG1546	Belongs to the CinA family
AMS64_03570	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMS64_03580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMS64_03585	COG0527	aspartate kinase activity
AMS64_03590	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AMS64_03615	COG1686	Belongs to the peptidase S11 family
AMS64_03620	COG0586	Pfam SNARE associated Golgi protein
AMS64_03625	COG1253	flavin adenine dinucleotide binding
AMS64_03630	COG0252	asparaginase activity
AMS64_03645	COG1609	Transcriptional regulator
AMS64_03650	COG1263	PTS System
AMS64_03650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_03655	COG0366	Alpha amylase catalytic
AMS64_03660	COG0110	maltose O-acetyltransferase activity
AMS64_03670	COG0564	pseudouridine synthase activity
AMS64_03675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMS64_03705	COG2926	Belongs to the UPF0265 family
AMS64_03715	COG0561	phosphatase activity
AMS64_03725	COG1058	Belongs to the CinA family
AMS64_03725	COG1546	Belongs to the CinA family
AMS64_03735	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AMS64_03745	COG1522	sequence-specific DNA binding
AMS64_03750	COG1368	sulfuric ester hydrolase activity
AMS64_03785	COG4221	oxidoreductase activity
AMS64_03800	COG1979	alcohol dehydrogenase
AMS64_03805	COG1803	Methylglyoxal synthase
AMS64_03830	COG1444	tRNA N-acetyltransferase activity
AMS64_03835	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_03840	COG0784	Response regulator, receiver
AMS64_03840	COG0835	chemotaxis
AMS64_03850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AMS64_03855	COG2949	membrane
AMS64_03860	COG3291	Pkd domain containing protein
AMS64_03865	COG0318	PFAM AMP-dependent synthetase and ligase
AMS64_03870	COG1441	menaquinone biosynthetic process
AMS64_03875	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AMS64_03880	COG0596	Alpha beta hydrolase
AMS64_03885	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AMS64_03890	COG1169	isochorismate synthase
AMS64_03895	COG1575	Belongs to the MenA family. Type 1 subfamily
AMS64_03915	COG0513	Belongs to the DEAD box helicase family
AMS64_03920	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_03925	COG1988	membrane-bound metal-dependent
AMS64_03930	COG1671	Belongs to the UPF0178 family
AMS64_03950	COG0484	heat shock protein binding
AMS64_03960	COG3722	fumarate hydratase activity
AMS64_03965	COG0246	Mannitol dehydrogenase
AMS64_03970	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_03970	COG2213	PTS system mannitol-specific
AMS64_03975	COG1560	Kdo2-lipid A biosynthetic process
AMS64_03980	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMS64_03980	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMS64_03985	COG1538	Outer membrane efflux protein
AMS64_03990	COG0494	nUDIX hydrolase
AMS64_03995	COG3151	Protein conserved in bacteria
AMS64_04005	COG3150	esterase
AMS64_04010	COG0187	DNA topoisomerase II activity
AMS64_04030	COG3104	oligopeptide transport
AMS64_04065	COG0583	DNA-binding transcription factor activity
AMS64_04070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMS64_04090	COG0204	Acyl-transferase
AMS64_04095	COG1842	Phage shock protein A
AMS64_04110	COG2827	Endonuclease containing a URI domain
AMS64_04125	COG1573	uracil-dna glycosylase
AMS64_04130	COG0697	spore germination
AMS64_04135	COG0583	DNA-binding transcription factor activity
AMS64_04140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMS64_04145	COG1121	(ABC) transporter
AMS64_04150	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AMS64_04170	COG0739	heme binding
AMS64_04180	COG3068	Protein conserved in bacteria
AMS64_04200	COG0617	tRNA 3'-terminal CCA addition
AMS64_04205	COG1194	a g-specific adenine glycosylase
AMS64_04210	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AMS64_04220	COG3111	PFAM Bacterial OB fold (BOF) protein
AMS64_04225	COG3240	lipase activity
AMS64_04230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AMS64_04230	COG2885	chlorophyll binding
AMS64_04235	COG3706	GGDEF domain
AMS64_04240	COG0557	exoribonuclease II activity
AMS64_04275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMS64_04285	COG2153	protein acetylation
AMS64_04290	COG0513	Belongs to the DEAD box helicase family
AMS64_04295	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AMS64_04325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMS64_04330	COG0840	transmembrane signaling receptor activity
AMS64_04340	COG4166	transmembrane transport
AMS64_04350	COG0110	maltose O-acetyltransferase activity
AMS64_04360	COG1024	Enoyl-CoA hydratase
AMS64_04375	COG4221	oxidoreductase activity
AMS64_04380	COG0442	prolyl-tRNA aminoacylation
AMS64_04385	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMS64_04390	COG3009	Protein conserved in bacteria
AMS64_04395	COG3008	intermembrane lipid transfer
AMS64_04395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMS64_04400	COG2995	paraquat-inducible protein a
AMS64_04410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_04420	COG4251	negative regulation of phosphorylation
AMS64_04420	COG3706	GGDEF domain
AMS64_04420	COG2203	Gaf domain
AMS64_04420	COG5001	Diguanylate cyclase
AMS64_04425	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AMS64_04435	COG3916	Acyl-homoserine-lactone synthase
AMS64_04440	COG2771	luxR family
AMS64_04450	COG0840	transmembrane signaling receptor activity
AMS64_04455	COG0632	four-way junction helicase activity
AMS64_04460	COG2255	four-way junction helicase activity
AMS64_04470	COG1294	oxidase, subunit
AMS64_04480	COG0824	Thioesterase
AMS64_04485	COG0811	peptide transport
AMS64_04500	COG0823	Involved in the tonB-independent uptake of proteins
AMS64_04505	COG2885	chlorophyll binding
AMS64_04510	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AMS64_04565	COG0733	neurotransmitter:sodium symporter activity
AMS64_04575	COG0733	neurotransmitter:sodium symporter activity
AMS64_04590	COG0561	phosphatase activity
AMS64_04605	COG1522	sequence-specific DNA binding
AMS64_04640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMS64_04645	COG1640	4-alpha-glucanotransferase
AMS64_04650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMS64_04655	COG0676	glucose-6-phosphate 1-epimerase activity
AMS64_04660	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMS64_04665	COG0840	transmembrane signaling receptor activity
AMS64_04670	COG1585	Membrane protein implicated in regulation of membrane protease activity
AMS64_04675	COG0330	HflC and HflK could
AMS64_04680	COG1648	precorrin-2 dehydrogenase activity
AMS64_04680	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMS64_04685	COG0175	sulfate reduction
AMS64_04690	COG2895	sulfate adenylyltransferase (ATP) activity
AMS64_04695	COG0471	metal ion transport
AMS64_04695	COG3273	potassium ion transport
AMS64_04700	COG0529	Catalyzes the synthesis of activated sulfate
AMS64_04710	COG0840	transmembrane signaling receptor activity
AMS64_04745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AMS64_04760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMS64_04765	COG3437	response regulator, receiver
AMS64_04765	COG0784	Response regulator, receiver
AMS64_04775	COG2076	Multidrug Resistance protein
AMS64_04780	COG2076	Multidrug Resistance protein
AMS64_04785	COG0346	lactoylglutathione lyase activity
AMS64_04790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMS64_04795	COG1643	Atp-dependent helicase
AMS64_04805	COG1489	DNA binding
AMS64_04810	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AMS64_04815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_04825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AMS64_04830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMS64_04835	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMS64_04880	COG0842	Transport permease protein
AMS64_04885	COG1131	(ABC) transporter
AMS64_04900	COG0163	prenyltransferase activity
AMS64_04905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMS64_04910	COG0671	phosphoesterase, PA-phosphatase related
AMS64_04915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMS64_04920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_04925	COG1151	hydroxylamine reductase activity
AMS64_04930	COG0783	Belongs to the Dps family
AMS64_04935	COG3023	N-Acetylmuramoyl-L-alanine amidase
AMS64_04940	COG4807	Protein conserved in bacteria
AMS64_04950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMS64_04955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMS64_04960	COG3956	TIGRFAM MazG family protein
AMS64_04965	COG0504	CTP synthase activity
AMS64_04970	COG0148	phosphopyruvate hydratase activity
AMS64_04985	COG2801	Transposase and inactivated derivatives
AMS64_05020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AMS64_05030	COG0488	(ABC) transporter
AMS64_05050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMS64_05065	COG1794	racemase activity, acting on amino acids and derivatives
AMS64_05075	COG2731	YhcH YjgK YiaL family protein
AMS64_05085	COG0668	transmembrane transport
AMS64_05090	COG1376	ErfK ybiS ycfS ynhG family protein
AMS64_05100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMS64_05105	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AMS64_05110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMS64_05120	COG0585	pseudouridine synthase activity
AMS64_05125	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMS64_05130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMS64_05135	COG1238	metal cluster binding
AMS64_05150	COG1902	pentaerythritol trinitrate reductase activity
AMS64_05170	COG2957	Belongs to the agmatine deiminase family
AMS64_05175	COG0154	amidase activity
AMS64_05230	COG0513	Belongs to the DEAD box helicase family
AMS64_05235	COG2199	diguanylate cyclase activity
AMS64_05235	COG2203	Gaf domain
AMS64_05245	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
AMS64_05250	COG1858	cytochrome C peroxidase
AMS64_05295	COG2816	NAD+ diphosphatase activity
AMS64_05330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMS64_05345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMS64_05350	COG4991	sh3 domain protein
AMS64_05360	COG2816	NAD+ diphosphatase activity
AMS64_05365	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMS64_05370	COG1940	carbohydrate kinase activity
AMS64_05375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMS64_05380	COG0126	phosphoglycerate kinase activity
AMS64_05385	COG0191	fructose-bisphosphate aldolase activity
AMS64_05390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_05410	COG4232	protein-disulfide reductase activity
AMS64_05435	COG0354	folic acid binding
AMS64_05440	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AMS64_05450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMS64_05455	COG1595	DNA-templated transcription, initiation
AMS64_05460	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
AMS64_05465	COG3026	antisigma factor binding
AMS64_05475	COG0481	GTPase activity
AMS64_05480	COG0681	Belongs to the peptidase S26 family
AMS64_05495	COG1381	Involved in DNA repair and RecF pathway recombination
AMS64_05500	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMS64_05510	COG2350	Protein conserved in bacteria
AMS64_05515	COG2917	probably involved in intracellular septation
AMS64_05520	COG0076	glutamate decarboxylase activity
AMS64_05525	COG1272	protein, Hemolysin III
AMS64_05530	COG2985	domain, Protein
AMS64_05530	COG0569	domain protein
AMS64_05550	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
AMS64_05585	COG4974	Belongs to the 'phage' integrase family
AMS64_05590	COG3541	Predicted nucleotidyltransferase
AMS64_05610	COG0582	viral genome integration into host DNA
AMS64_05635	COG2313	pseudouridylate synthase activity
AMS64_05640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMS64_05675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMS64_05680	COG1765	OsmC-like protein
AMS64_05695	COG3954	Phosphoribulokinase
AMS64_05700	COG3089	Belongs to the UPF0270 family
AMS64_05705	COG4251	negative regulation of phosphorylation
AMS64_05705	COG2203	Gaf domain
AMS64_05705	COG3706	GGDEF domain
AMS64_05705	COG5001	Diguanylate cyclase
AMS64_05710	COG0429	hydrolase of the alpha beta-hydrolase fold
AMS64_05715	COG0784	Response regulator, receiver
AMS64_05715	COG0835	chemotaxis
AMS64_05725	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AMS64_05730	COG1047	Peptidyl-prolyl cis-trans
AMS64_05735	COG2900	Belongs to the SlyX family
AMS64_05745	COG0545	Peptidyl-prolyl cis-trans isomerase
AMS64_05750	COG2204	response regulator
AMS64_05770	COG0737	Belongs to the 5'-nucleotidase family
AMS64_05785	COG0305	Participates in initiation and elongation during chromosome replication
AMS64_05790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMS64_05795	COG0432	Pfam Uncharacterised protein family UPF0047
AMS64_05815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_05825	COG3721	Heme iron utilization protein
AMS64_05830	COG0748	coenzyme F420 binding
AMS64_05865	COG3501	Rhs element vgr protein
AMS64_05890	COG2814	Major facilitator Superfamily
AMS64_05900	COG3655	Transcriptional regulator
AMS64_05910	COG0784	Response regulator, receiver
AMS64_05910	COG2205	protein histidine kinase activity
AMS64_05910	COG5002	protein histidine kinase activity
AMS64_05925	COG3706	GGDEF domain
AMS64_05940	COG3397	chitin binding
AMS64_05980	COG0784	Response regulator, receiver
AMS64_05980	COG0835	chemotaxis
AMS64_05985	COG2755	lipolytic protein G-D-S-L family
AMS64_05990	COG4181	ATPase activity
AMS64_05995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AMS64_06000	COG1090	epimerase
AMS64_06005	COG2200	EAL domain
AMS64_06010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMS64_06015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMS64_06020	COG3171	Protein conserved in bacteria
AMS64_06025	COG2066	Belongs to the glutaminase family
AMS64_06030	COG2897	thiosulfate sulfurtransferase activity
AMS64_06045	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMS64_06055	COG2966	Psort location CytoplasmicMembrane, score
AMS64_06060	COG3610	response to peptide
AMS64_06075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMS64_06080	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMS64_06090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMS64_06095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMS64_06105	COG0786	glutamate:sodium symporter activity
AMS64_06110	COG0252	asparaginase activity
AMS64_06115	COG3139	Protein of unknown function (DUF1315)
AMS64_06165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMS64_06170	COG0321	lipoyl(octanoyl) transferase activity
AMS64_06175	COG2921	Belongs to the UPF0250 family
AMS64_06180	COG1686	Belongs to the peptidase S11 family
AMS64_06185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMS64_06190	COG2951	lytic endotransglycosylase activity
AMS64_06195	COG0772	Belongs to the SEDS family
AMS64_06200	COG0768	penicillin binding
AMS64_06205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMS64_06210	COG0799	negative regulation of ribosome biogenesis
AMS64_06215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMS64_06230	COG0495	leucyl-tRNA aminoacylation
AMS64_06235	COG2888	peptidyl-tyrosine sulfation
AMS64_06240	COG0312	modulator of DNA gyrase
AMS64_06250	COG0716	FMN binding
AMS64_06255	COG4974	Belongs to the 'phage' integrase family
AMS64_06265	COG1970	mechanosensitive ion channel activity
AMS64_06280	COG0789	Transcriptional regulator
AMS64_06290	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_06295	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMS64_06300	COG4535	Mg2 and Co2 transporter CorC
AMS64_06305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMS64_06310	COG1702	phosphate starvation-inducible protein PhoH
AMS64_06315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMS64_06320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMS64_06325	COG1335	isochorismatase
AMS64_06335	COG3706	GGDEF domain
AMS64_06340	COG0583	DNA-binding transcription factor activity
AMS64_06360	COG3706	GGDEF domain
AMS64_06370	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMS64_06380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMS64_06390	COG0516	GMP reductase activity
AMS64_06410	COG0642	Histidine kinase
AMS64_06415	COG0745	RESPONSE REGULATOR receiver
AMS64_06425	COG4221	oxidoreductase activity
AMS64_06450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_06465	COG3214	Protein conserved in bacteria
AMS64_06475	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMS64_06480	COG0700	Nucleoside recognition
AMS64_06485	COG3366	ferrous iron transmembrane transporter activity
AMS64_06490	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AMS64_06495	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AMS64_06500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMS64_06505	COG1053	succinate dehydrogenase
AMS64_06515	COG0584	glycerophosphoryl diester phosphodiesterase
AMS64_06520	COG1511	domain protein
AMS64_06520	COG3264	Mechanosensitive ion channel
AMS64_06530	COG0739	heme binding
AMS64_06540	COG0583	DNA-binding transcription factor activity
AMS64_06560	COG0583	DNA-binding transcription factor activity
AMS64_06565	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMS64_06595	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMS64_06600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMS64_06610	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AMS64_06615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMS64_06625	COG0180	Tryptophanyl-tRNA synthetase
AMS64_06635	COG0512	Glutamine amidotransferase of anthranilate synthase
AMS64_06640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMS64_06650	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_06665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_06670	COG2814	Major facilitator Superfamily
AMS64_06675	COG0366	Alpha amylase catalytic
AMS64_06685	COG0443	Heat shock 70 kDa protein
AMS64_06715	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AMS64_06725	COG0471	metal ion transport
AMS64_06725	COG0490	domain, Protein
AMS64_06780	COG0012	GTP binding
AMS64_06785	COG0193	aminoacyl-tRNA hydrolase activity
AMS64_06790	COG0737	Belongs to the 5'-nucleotidase family
AMS64_06795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMS64_06805	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMS64_06810	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AMS64_06815	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMS64_06820	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMS64_06825	COG2890	protein-(glutamine-N5) methyltransferase activity
AMS64_06835	COG2912	Transglutaminase-like superfamily
AMS64_06840	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMS64_06845	COG1301	dicarboxylic acid transport
AMS64_06860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMS64_06870	COG3408	Glycogen debranching enzyme
AMS64_06870	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AMS64_06880	COG1881	PFAM PEBP family protein
AMS64_06900	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMS64_06910	COG0583	DNA-binding transcription factor activity
AMS64_06915	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_06920	COG0616	signal peptide processing
AMS64_06925	COG2211	Major facilitator Superfamily
AMS64_06930	COG3706	GGDEF domain
AMS64_06935	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AMS64_06945	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_06975	COG3724	N-succinylarginine dihydrolase activity
AMS64_06980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMS64_06990	COG0840	transmembrane signaling receptor activity
AMS64_07000	COG2971	BadF BadG BcrA BcrD
AMS64_07010	COG4608	Belongs to the ABC transporter superfamily
AMS64_07015	COG0444	Belongs to the ABC transporter superfamily
AMS64_07020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMS64_07065	COG3220	belongs to the UPF0276 family
AMS64_07095	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_07100	COG1289	transmembrane transporter activity
AMS64_07105	COG0303	'Molybdopterin
AMS64_07110	COG0746	molybdenum cofactor guanylyltransferase activity
AMS64_07120	COG4662	Binding-protein-dependent transport system inner membrane component
AMS64_07130	COG2204	response regulator
AMS64_07135	COG3852	Histidine kinase
AMS64_07145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMS64_07175	COG3383	formate dehydrogenase (NAD+) activity
AMS64_07175	COG3383	formate dehydrogenase (NAD+) activity
AMS64_07180	COG0437	4 iron, 4 sulfur cluster binding
AMS64_07200	COG0281	malic enzyme
AMS64_07225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_07255	COG0837	glucose binding
AMS64_07260	COG1737	Transcriptional regulator
AMS64_07265	COG0469	pyruvate kinase activity
AMS64_07285	COG1677	Flagellar hook-basal body complex protein FliE
AMS64_07295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMS64_07345	COG1987	bacterial-type flagellum assembly
AMS64_07350	COG1684	flagellar biosynthetic protein fliR
AMS64_07360	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMS64_07370	COG0455	bacterial-type flagellum organization
AMS64_07385	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AMS64_07390	COG0643	Histidine kinase
AMS64_07390	COG2198	Histidine kinase
AMS64_07395	COG2201	protein-glutamate methylesterase activity
AMS64_07400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_07405	COG1360	Flagellar Motor Protein
AMS64_07410	COG1192	Involved in chromosome partitioning
AMS64_07420	COG0835	chemotaxis
AMS64_07435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMS64_07440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMS64_07445	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMS64_07450	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AMS64_07455	COG1138	Cytochrome C-type biogenesis protein
AMS64_07460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMS64_07465	COG3088	subunit of a heme lyase
AMS64_07465	COG4235	cytochrome complex assembly
AMS64_07475	COG2853	Lipoprotein
AMS64_07485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AMS64_07490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMS64_07500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMS64_07505	COG1882	Formate acetyltransferase
AMS64_07515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMS64_07515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMS64_07550	COG0259	pyridoxamine-phosphate oxidase activity
AMS64_07555	COG0625	glutathione transferase activity
AMS64_07575	COG2850	peptidyl-arginine hydroxylation
AMS64_07580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMS64_07585	COG2915	High frequency lysogenization protein hflD homolog
AMS64_07590	COG0482	sulfurtransferase activity
AMS64_07600	COG1187	pseudouridine synthase activity
AMS64_07610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_07620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_07620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_07620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_07640	COG1609	Transcriptional regulator
AMS64_07645	COG1263	PTS System
AMS64_07645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_07650	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMS64_07675	COG4792	protein secretion
AMS64_07680	COG4791	protein targeting
AMS64_07685	COG4794	Type iii secretion
AMS64_07690	COG4790	Type iii secretion
AMS64_07695	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMS64_07735	COG0457	Tetratricopeptide repeat
AMS64_07760	COG0457	Tetratricopeptide repeat
AMS64_07930	COG0582	viral genome integration into host DNA
AMS64_07935	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMS64_07940	COG0326	Molecular chaperone. Has ATPase activity
AMS64_07945	COG4172	Belongs to the ABC transporter superfamily
AMS64_07950	COG4172	Belongs to the ABC transporter superfamily
AMS64_07955	COG4171	peptide transport system, permease
AMS64_07960	COG4168	peptide transport system, permease
AMS64_07965	COG0747	negative chemotaxis
AMS64_07970	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AMS64_07975	COG1842	Phage shock protein A
AMS64_07990	COG3106	COG3106 Predicted ATPase
AMS64_07995	COG3768	UPF0283 membrane protein
AMS64_08005	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMS64_08020	COG2199	diguanylate cyclase activity
AMS64_08025	COG2885	chlorophyll binding
AMS64_08030	COG0861	Integral membrane protein TerC family
AMS64_08065	COG2910	NAD(P)H-binding
AMS64_08070	COG0583	DNA-binding transcription factor activity
AMS64_08080	COG4977	sequence-specific DNA binding
AMS64_08085	COG4774	siderophore transport
AMS64_08095	COG0583	DNA-binding transcription factor activity
AMS64_08100	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMS64_08110	COG0583	DNA-binding transcription factor activity
AMS64_08115	COG2723	6-phospho-beta-galactosidase activity
AMS64_08120	COG1944	ATP diphosphatase activity
AMS64_08125	COG2116	formate transmembrane transporter activity
AMS64_08130	COG1882	Formate acetyltransferase
AMS64_08155	COG0058	SHG alpha-glucan phosphorylase activity
AMS64_08160	COG0471	metal ion transport
AMS64_08165	COG3118	belongs to the thioredoxin family
AMS64_08175	COG1132	(ABC) transporter
AMS64_08180	COG1132	(ABC) transporter
AMS64_08190	COG2501	S4 domain
AMS64_08205	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMS64_08245	COG2009	succinate dehydrogenase
AMS64_08250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AMS64_08255	COG1053	succinate dehydrogenase
AMS64_08265	COG0567	Dehydrogenase, E1 component
AMS64_08270	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMS64_08275	COG0045	succinate-CoA ligase (ADP-forming) activity
AMS64_08285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_08295	COG3842	ATPase activity
AMS64_08310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMS64_08320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_08335	COG3088	subunit of a heme lyase
AMS64_08335	COG4235	cytochrome complex assembly
AMS64_08345	COG1138	Cytochrome C-type biogenesis protein
AMS64_08350	COG3301	Polysulphide reductase, NrfD
AMS64_08355	COG0437	4 iron, 4 sulfur cluster binding
AMS64_08360	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AMS64_08375	COG0247	lactate metabolic process
AMS64_08380	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AMS64_08385	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMS64_08390	COG3012	SEC-C Motif Domain Protein
AMS64_08395	COG0840	transmembrane signaling receptor activity
AMS64_08400	COG1940	carbohydrate kinase activity
AMS64_08400	COG1846	Transcriptional regulator
AMS64_08410	COG0730	response to heat
AMS64_08415	COG0583	DNA-binding transcription factor activity
AMS64_08430	COG3593	DNA synthesis involved in DNA repair
AMS64_08465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMS64_08470	COG1011	Hydrolase
AMS64_08485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AMS64_08490	COG2832	Protein of unknown function (DUF454)
AMS64_08495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMS64_08500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMS64_08505	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMS64_08510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AMS64_08525	COG1560	Kdo2-lipid A biosynthetic process
AMS64_08530	COG1560	Kdo2-lipid A biosynthetic process
AMS64_08545	COG2199	diguanylate cyclase activity
AMS64_08545	COG2203	Gaf domain
AMS64_08555	COG0417	DNA replication proofreading
AMS64_08570	COG1451	nucleotide metabolic process
AMS64_08585	COG3069	C4-dicarboxylate transmembrane transporter activity
AMS64_08600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_08600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AMS64_08605	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMS64_08610	COG0569	domain protein
AMS64_08610	COG2985	domain, Protein
AMS64_08620	COG0556	nucleotide-excision repair
AMS64_08630	COG0586	Pfam SNARE associated Golgi protein
AMS64_08635	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AMS64_08640	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMS64_08650	COG4681	YaeQ
AMS64_08735	COG0534	Mate efflux family protein
AMS64_08750	COG0307	riboflavin synthase, alpha
AMS64_08760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMS64_08765	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMS64_08770	COG0697	spore germination
AMS64_08775	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMS64_08815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMS64_08825	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AMS64_08830	COG2894	cell division
AMS64_08835	COG0850	regulation of cytokinetic process
AMS64_08840	COG3100	YcgL domain-containing protein
AMS64_08845	COG1760	l-serine dehydratase
AMS64_08850	COG1760	l-serine dehydratase
AMS64_08855	COG3123	guanosine phosphorylase activity
AMS64_08860	COG1301	dicarboxylic acid transport
AMS64_08865	COG0205	6-phosphofructokinase activity
AMS64_08875	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AMS64_08880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMS64_08890	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AMS64_08895	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AMS64_08900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMS64_08935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMS64_08940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMS64_08945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMS64_08955	COG0549	Belongs to the carbamate kinase family
AMS64_08960	COG0697	spore germination
AMS64_08970	COG3608	succinylglutamate desuccinylase aspartoacylase
AMS64_08970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AMS64_08975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMS64_08980	COG2068	MobA-Related Protein
AMS64_08985	COG0493	'glutamate synthase
AMS64_08985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_08990	COG0402	S-adenosylhomocysteine deaminase activity
AMS64_08995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMS64_09000	COG2080	2 iron, 2 sulfur cluster binding
AMS64_09000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMS64_09005	COG2233	PERMEase
AMS64_09010	COG0402	S-adenosylhomocysteine deaminase activity
AMS64_09015	COG2252	PERMEase
AMS64_09025	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMS64_09030	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMS64_09035	COG2080	2 iron, 2 sulfur cluster binding
AMS64_09040	COG3134	Outer membrane lipoprotein
AMS64_09050	COG1288	antiporter activity
AMS64_09055	COG0318	PFAM AMP-dependent synthetase and ligase
AMS64_09060	COG3706	GGDEF domain
AMS64_09070	COG2801	Transposase and inactivated derivatives
AMS64_09080	COG0107	imidazoleglycerol-phosphate synthase activity
AMS64_09085	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMS64_09090	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMS64_09095	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMS64_09095	COG0131	Imidazoleglycerol-phosphate dehydratase
AMS64_09100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMS64_09105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMS64_09110	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMS64_09120	COG1199	ATP-dependent helicase activity
AMS64_09125	COG1214	PFAM Peptidase M22, glycoprotease
AMS64_09135	COG2267	carboxylic ester hydrolase activity
AMS64_09140	COG0318	PFAM AMP-dependent synthetase and ligase
AMS64_09150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMS64_09155	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AMS64_09160	COG0709	Synthesizes selenophosphate from selenide and ATP
AMS64_09170	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMS64_09175	COG0840	transmembrane signaling receptor activity
AMS64_09180	COG1254	Belongs to the acylphosphatase family
AMS64_09190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_09190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_09195	COG0489	protein tyrosine kinase activity
AMS64_09200	COG0572	uridine kinase
AMS64_09205	COG0717	Belongs to the dCTP deaminase family
AMS64_09210	COG0306	phosphate transporter
AMS64_09215	COG2140	Oxalate decarboxylase
AMS64_09220	COG1609	Transcriptional regulator
AMS64_09235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_09235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_09240	COG3715	PTS system
AMS64_09245	COG3716	PTS system mannose fructose sorbose family IID component
AMS64_09250	COG2942	2-epimerase
AMS64_09255	COG3313	Fe-S protein
AMS64_09260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AMS64_09265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_09270	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMS64_09275	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMS64_09285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMS64_09295	COG0366	Alpha amylase catalytic
AMS64_09310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMS64_09315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMS64_09320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMS64_09325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMS64_09330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMS64_09335	COG0072	phenylalanine-tRNA ligase activity
AMS64_09335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_09340	COG0776	regulation of translation
AMS64_09345	COG2205	protein histidine kinase activity
AMS64_09345	COG0784	Response regulator, receiver
AMS64_09360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMS64_09370	COG5001	Diguanylate cyclase
AMS64_09370	COG3300	MHYT domain
AMS64_09375	COG1609	Transcriptional regulator
AMS64_09380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMS64_09385	COG1879	ABC-type sugar transport system periplasmic component
AMS64_09390	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMS64_09395	COG1129	ABC transporter
AMS64_09400	COG1869	D-ribose catabolic process
AMS64_09405	COG0625	glutathione transferase activity
AMS64_09415	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMS64_09420	COG1177	transmembrane transport
AMS64_09425	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMS64_09445	COG0037	tRNA processing
AMS64_09450	COG0589	response to stress
AMS64_09455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMS64_09470	COG2217	Heavy metal translocating P-type atpase
AMS64_09480	COG2010	Cytochrome c
AMS64_09495	COG3278	Belongs to the heme-copper respiratory oxidase family
AMS64_09505	COG1956	GAF domain-containing protein
AMS64_09510	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AMS64_09520	COG0308	aminopeptidase N
AMS64_09530	COG2902	Dehydrogenase
AMS64_09535	COG0167	dihydroorotate dehydrogenase activity
AMS64_09545	COG0254	rRNA binding
AMS64_09550	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMS64_09555	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMS64_09555	COG0116	Belongs to the methyltransferase superfamily
AMS64_09565	COG0488	(ABC) transporter
AMS64_09570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMS64_09575	COG1067	ATP-dependent peptidase activity
AMS64_09655	COG3141	response to X-ray
AMS64_09660	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AMS64_09665	COG4221	oxidoreductase activity
AMS64_09710	COG0372	Belongs to the citrate synthase family
AMS64_09715	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AMS64_09725	COG2995	paraquat-inducible protein a
AMS64_09730	COG3008	intermembrane lipid transfer
AMS64_09735	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AMS64_09735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMS64_09745	COG2801	Transposase and inactivated derivatives
AMS64_09755	COG3093	addiction module antidote protein HigA
AMS64_09775	COG0084	hydrolase, TatD family'
AMS64_09780	COG0470	DNA polymerase III
AMS64_09785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMS64_09790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMS64_09795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMS64_09800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMS64_09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMS64_09810	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_09820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMS64_09825	COG0416	fatty acid biosynthetic process
AMS64_09830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMS64_09835	COG1399	metal-binding, possibly nucleic acid-binding protein
AMS64_09840	COG0424	maF-like protein
AMS64_09855	COG1530	ribonuclease E activity
AMS64_09860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_09860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_09860	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AMS64_09865	COG1105	Belongs to the carbohydrate kinase PfkB family
AMS64_09870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_09870	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_09875	COG1609	Transcriptional regulator
AMS64_09880	COG0814	amino acid
AMS64_09890	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AMS64_09900	COG0513	Belongs to the DEAD box helicase family
AMS64_09910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMS64_09915	COG2890	protein-(glutamine-N5) methyltransferase activity
AMS64_09920	COG2840	Smr protein MutS2
AMS64_09925	COG3706	GGDEF domain
AMS64_09930	COG0406	alpha-ribazole phosphatase activity
AMS64_09945	COG2824	Alkylphosphonate utilization operon protein PhnA
AMS64_09960	COG0494	nUDIX hydrolase
AMS64_09965	COG0814	amino acid
AMS64_09975	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AMS64_09980	COG0514	ATP-dependent DNA helicase (RecQ)
AMS64_09985	COG2766	serine protein kinase
AMS64_09990	COG2718	Belongs to the UPF0229 family
AMS64_09995	COG2719	SpoVR family
AMS64_10000	COG1024	Enoyl-CoA hydratase
AMS64_10000	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMS64_10005	COG0183	Belongs to the thiolase family
AMS64_10010	COG0714	Associated with various cellular activities
AMS64_10030	COG2304	oxidoreductase activity
AMS64_10040	COG1595	DNA-templated transcription, initiation
AMS64_10050	COG2067	long-chain fatty acid transport protein
AMS64_10055	COG2067	long-chain fatty acid transport protein
AMS64_10060	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AMS64_10075	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AMS64_10085	COG1643	Atp-dependent helicase
AMS64_10100	COG3119	arylsulfatase activity
AMS64_10105	COG0714	Associated with various cellular activities
AMS64_10125	COG2304	oxidoreductase activity
AMS64_10150	COG0641	radical SAM
AMS64_10155	COG2925	Exonuclease
AMS64_10165	COG3345	alpha-galactosidase
AMS64_10170	COG1380	Effector of murein hydrolase LrgA
AMS64_10175	COG1346	cytolysis
AMS64_10180	COG0295	cytidine deaminase activity
AMS64_10185	COG3033	Beta-eliminating lyase
AMS64_10190	COG3046	protein related to deoxyribodipyrimidine photolyase
AMS64_10195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_10200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMS64_10220	COG3383	formate dehydrogenase (NAD+) activity
AMS64_10225	COG3383	formate dehydrogenase (NAD+) activity
AMS64_10230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_10240	COG3158	transport of potassium into the cell
AMS64_10245	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_10250	COG0651	ATP synthesis coupled electron transport
AMS64_10255	COG0650	Formate hydrogenlyase subunit 4
AMS64_10260	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AMS64_10260	COG3261	NADH dehydrogenase
AMS64_10265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_10270	COG3260	NADH ubiquinone oxidoreductase 20
AMS64_10280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMS64_10285	COG1921	L-seryl-tRNASec selenium transferase activity
AMS64_10295	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMS64_10300	COG0298	carbon dioxide binding
AMS64_10310	COG0309	Hydrogenase expression formation protein (HypE)
AMS64_10315	COG0375	protein maturation
AMS64_10320	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMS64_10330	COG3842	ATPase activity
AMS64_10335	COG0444	Belongs to the ABC transporter superfamily
AMS64_10340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMS64_10345	COG0601	transmembrane transport
AMS64_10355	COG1773	rubredoxin
AMS64_10360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMS64_10365	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMS64_10370	COG5557	Pfam Polysulphide reductase, NrfD
AMS64_10375	COG0437	4 iron, 4 sulfur cluster binding
AMS64_10380	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AMS64_10390	COG0438	transferase activity, transferring glycosyl groups
AMS64_10395	COG0438	transferase activity, transferring glycosyl groups
AMS64_10415	COG0438	transferase activity, transferring glycosyl groups
AMS64_10455	COG0438	transferase activity, transferring glycosyl groups
AMS64_10460	COG1215	transferase activity, transferring glycosyl groups
AMS64_10465	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMS64_10505	COG2205	protein histidine kinase activity
AMS64_10505	COG0784	Response regulator, receiver
AMS64_10545	COG5489	Protein of unknown function (DUF736)
AMS64_10575	COG2333	competence protein COMEC
AMS64_10575	COG0658	competence protein
AMS64_10630	COG3267	Type II secretory pathway component ExeA
AMS64_10630	COG3409	Peptidoglycan-binding domain 1 protein
AMS64_10645	COG0730	response to heat
AMS64_10655	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_10665	COG1024	Enoyl-CoA hydratase
AMS64_10670	COG1024	Enoyl-CoA hydratase
AMS64_10675	COG1960	acyl-CoA dehydrogenase activity
AMS64_10680	COG1960	acyl-CoA dehydrogenase activity
AMS64_10685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMS64_10690	COG1024	Enoyl-CoA hydratase
AMS64_10720	COG1584	GPR1 FUN34 yaaH family protein
AMS64_10740	COG1115	amino acid carrier protein
AMS64_10770	COG1024	Enoyl-CoA hydratase
AMS64_10785	COG3162	membrane
AMS64_10790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMS64_10825	COG0488	(ABC) transporter
AMS64_10830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMS64_10835	COG0776	regulation of translation
AMS64_10840	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMS64_10845	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMS64_10850	COG0740	serine-type endopeptidase activity
AMS64_10855	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMS64_10865	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AMS64_10870	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMS64_10875	COG1136	(ABC) transporter
AMS64_10880	COG4591	ABC-type transport system involved in lipoprotein release permease component
AMS64_10890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AMS64_10895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AMS64_10900	COG4166	transmembrane transport
AMS64_10905	COG0697	spore germination
AMS64_10915	COG2062	phosphohistidine phosphatase, SixA
AMS64_10920	COG1025	Belongs to the peptidase M16 family
AMS64_10950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMS64_10950	COG0519	Catalyzes the synthesis of GMP from XMP
AMS64_10955	COG0517	IMP dehydrogenase activity
AMS64_10955	COG0516	GMP reductase activity
AMS64_10960	COG3038	cytochrome b561
AMS64_10965	COG1570	exodeoxyribonuclease VII activity
AMS64_10970	COG2188	Transcriptional regulator
AMS64_10975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_10975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_10975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_10980	COG0383	alpha-mannosidase activity
AMS64_10985	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMS64_10995	COG0386	Belongs to the glutathione peroxidase family
AMS64_11000	COG0513	Belongs to the DEAD box helicase family
AMS64_11015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_11020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMS64_11025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AMS64_11045	COG0598	Magnesium transport protein CorA
AMS64_11075	COG5001	Diguanylate cyclase
AMS64_11075	COG3300	MHYT domain
AMS64_11090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMS64_11100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMS64_11105	COG0563	adenylate kinase activity
AMS64_11115	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMS64_11120	COG1286	toxin biosynthetic process
AMS64_11125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMS64_11130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMS64_11135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AMS64_11140	COG0531	amino acid
AMS64_11140	COG1674	ftsk spoiiie
AMS64_11150	COG0686	Belongs to the AlaDH PNT family
AMS64_11155	COG0492	ferredoxin-NADP+ reductase activity
AMS64_11160	COG3706	GGDEF domain
AMS64_11165	COG3134	Outer membrane lipoprotein
AMS64_11170	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMS64_11175	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AMS64_11180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMS64_11185	COG0542	response to heat
AMS64_11190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMS64_11195	COG1278	Cold shock
AMS64_11200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMS64_11225	COG2205	protein histidine kinase activity
AMS64_11235	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMS64_11235	COG0392	lysyltransferase activity
AMS64_11370	COG0672	)-iron permease
AMS64_11390	COG2814	Major facilitator Superfamily
AMS64_11405	COG1136	(ABC) transporter
AMS64_11425	COG0596	Alpha beta hydrolase
AMS64_11445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMS64_11450	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMS64_11450	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMS64_11455	COG0527	aspartate kinase activity
AMS64_11465	COG1368	sulfuric ester hydrolase activity
AMS64_11470	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMS64_11475	COG4667	esterase of the alpha-beta hydrolase superfamily
AMS64_11490	COG2221	Nitrite and sulphite reductase 4Fe-4S
AMS64_11495	COG1648	precorrin-2 dehydrogenase activity
AMS64_11495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMS64_11505	COG0393	Putative heavy-metal-binding
AMS64_11510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AMS64_11515	COG0285	dihydrofolate synthase activity
AMS64_11520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMS64_11525	COG0101	tRNA pseudouridine synthase activity
AMS64_11535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMS64_11540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMS64_11545	COG0671	phosphoesterase, PA-phosphatase related
AMS64_11550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMS64_11555	COG2056	Na+-H+ antiporter family
AMS64_11560	COG0047	phosphoribosylformylglycinamidine synthase activity
AMS64_11560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMS64_11565	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AMS64_11570	COG1645	bacterial-type flagellum-dependent swarming motility
AMS64_11575	COG1160	GTP binding
AMS64_11580	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMS64_11585	COG2976	Protein conserved in bacteria
AMS64_11590	COG0124	histidyl-tRNA synthetase
AMS64_11610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMS64_11615	COG0105	UTP biosynthetic process
AMS64_11630	COG0633	Ferredoxin
AMS64_11635	COG0443	Heat shock 70 kDa protein
AMS64_11640	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMS64_11650	COG0822	iron-sulfur transferase activity
AMS64_11655	COG1104	cysteine desulfurase activity
AMS64_11700	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_11705	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_11710	COG1862	Preprotein translocase
AMS64_11715	COG0343	queuine tRNA-ribosyltransferase activity
AMS64_11720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMS64_11725	COG0517	IMP dehydrogenase activity
AMS64_11730	COG0450	alkyl hydroperoxide reductase
AMS64_11735	COG3634	alkyl hydroperoxide reductase activity
AMS64_11790	COG1242	4 iron, 4 sulfur cluster binding
AMS64_11800	COG0069	glutamate synthase activity
AMS64_11800	COG0070	glutamate synthase
AMS64_11800	COG0067	glutamate synthase
AMS64_11805	COG0493	'glutamate synthase
AMS64_11815	COG0513	Belongs to the DEAD box helicase family
AMS64_11840	COG0023	Translation Initiation Factor
AMS64_11845	COG2119	membrane
AMS64_11885	COG0215	cysteine-tRNA ligase activity
AMS64_11890	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMS64_11900	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_11910	COG2261	transglycosylase associated protein
AMS64_11915	COG0642	Histidine kinase
AMS64_11985	COG0582	viral genome integration into host DNA
AMS64_12085	COG0616	signal peptide processing
AMS64_12100	COG1802	Transcriptional regulator
AMS64_12100	COG4626	Terminase
AMS64_12135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMS64_12140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMS64_12330	COG0322	excinuclease ABC activity
AMS64_12335	COG2197	response regulator
AMS64_12340	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMS64_12345	COG2835	tetraacyldisaccharide 4'-kinase activity
AMS64_12350	COG1663	tetraacyldisaccharide 4'-kinase activity
AMS64_12360	COG0658	competence protein
AMS64_12360	COG2333	competence protein COMEC
AMS64_12375	COG1448	Aminotransferase
AMS64_12385	COG0583	DNA-binding transcription factor activity
AMS64_12390	COG3085	chromosome segregation
AMS64_12395	COG4574	serine-type endopeptidase inhibitor activity
AMS64_12400	COG0584	glycerophosphoryl diester phosphodiesterase
AMS64_12410	COG1349	DNA-binding transcription factor activity
AMS64_12415	COG2271	Major facilitator Superfamily
AMS64_12420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMS64_12425	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMS64_12430	COG0840	transmembrane signaling receptor activity
AMS64_12440	COG0583	DNA-binding transcription factor activity
AMS64_12465	COG0656	L-ascorbic acid biosynthetic process
AMS64_12475	COG2814	Major facilitator Superfamily
AMS64_12480	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMS64_12490	COG3220	belongs to the UPF0276 family
AMS64_12510	COG1294	oxidase, subunit
AMS64_12520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMS64_12530	COG2979	Protein of unknown function (DUF533)
AMS64_12535	COG1607	acyl-coa hydrolase
AMS64_12540	COG0583	DNA-binding transcription factor activity
AMS64_12545	COG2807	transmembrane transport
AMS64_12550	COG1187	pseudouridine synthase activity
AMS64_12560	COG0346	lactoylglutathione lyase activity
AMS64_12585	COG4657	Part of a membrane complex involved in electron transport
AMS64_12590	COG2878	Part of a membrane complex involved in electron transport
AMS64_12600	COG4658	electron transport chain
AMS64_12605	COG4659	FMN binding
AMS64_12615	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMS64_12620	COG0346	lactoylglutathione lyase activity
AMS64_12655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMS64_12660	COG0505	Belongs to the CarA family
AMS64_12665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMS64_12680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMS64_12685	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AMS64_12690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMS64_12695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AMS64_12700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_12705	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AMS64_12735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMS64_12740	COG0861	Integral membrane protein TerC family
AMS64_12750	COG0444	Belongs to the ABC transporter superfamily
AMS64_12755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMS64_12760	COG0601	transmembrane transport
AMS64_12770	COG2095	MarC family integral membrane protein
AMS64_12775	COG1454	alcohol dehydrogenase
AMS64_12775	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_12780	COG0217	transcriptional regulatory protein
AMS64_12785	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMS64_12795	COG1801	Protein of unknown function DUF72
AMS64_12800	COG4106	trans-aconitate 2-methyltransferase activity
AMS64_12805	COG0500	methyltransferase
AMS64_12825	COG0450	alkyl hydroperoxide reductase
AMS64_12830	COG0583	DNA-binding transcription factor activity
AMS64_12835	COG0791	NLP P60 protein
AMS64_12840	COG0583	DNA-binding transcription factor activity
AMS64_12850	COG3048	D-serine ammonia-lyase activity
AMS64_12855	COG0538	isocitrate dehydrogenase activity
AMS64_12860	COG2207	Transcriptional regulator
AMS64_12865	COG1482	cell wall glycoprotein biosynthetic process
AMS64_12870	COG0840	transmembrane signaling receptor activity
AMS64_12875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AMS64_12890	COG3152	Membrane
AMS64_12925	COG1309	transcriptional regulator
AMS64_12955	COG0534	Mate efflux family protein
AMS64_12965	COG2841	Protein conserved in bacteria
AMS64_12975	COG5001	Diguanylate cyclase
AMS64_12975	COG3300	MHYT domain
AMS64_12980	COG3132	Protein of unknown function, DUF480
AMS64_13010	COG0708	Exodeoxyribonuclease III
AMS64_13045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_13050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_13060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMS64_13065	COG1120	ATPase activity
AMS64_13070	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_13075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_13080	COG2375	cellular response to nickel ion
AMS64_13085	COG3437	response regulator, receiver
AMS64_13085	COG0784	Response regulator, receiver
AMS64_13095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMS64_13100	COG0328	RNA-DNA hybrid ribonuclease activity
AMS64_13105	COG2226	methyltransferase
AMS64_13110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMS64_13115	COG1388	LysM domain
AMS64_13115	COG0741	lytic transglycosylase activity
AMS64_13140	COG5000	phosphorelay sensor kinase activity
AMS64_13140	COG5002	protein histidine kinase activity
AMS64_13145	COG0745	RESPONSE REGULATOR receiver
AMS64_13150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_13155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_13170	COG1388	LysM domain
AMS64_13170	COG1376	ErfK ybiS ycfS ynhG family protein
AMS64_13180	COG0471	metal ion transport
AMS64_13190	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AMS64_13195	COG0791	NLP P60 protein
AMS64_13205	COG3118	belongs to the thioredoxin family
AMS64_13215	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMS64_13220	COG0788	formyltetrahydrofolate deformylase activity
AMS64_13230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMS64_13250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMS64_13260	COG0436	Aminotransferase
AMS64_13265	COG1288	antiporter activity
AMS64_13270	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMS64_13285	COG2964	Protein conserved in bacteria
AMS64_13290	COG3681	Belongs to the UPF0597 family
AMS64_13300	COG0814	amino acid
AMS64_13320	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AMS64_13330	COG1166	arginine decarboxylase activity
AMS64_13335	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMS64_13360	COG2353	YceI-like domain
AMS64_13365	COG0583	DNA-binding transcription factor activity
AMS64_13375	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AMS64_13380	COG0840	transmembrane signaling receptor activity
AMS64_13385	COG0840	transmembrane signaling receptor activity
AMS64_13390	COG0302	gtp cyclohydrolase
AMS64_13400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMS64_13435	COG2267	carboxylic ester hydrolase activity
AMS64_13440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMS64_13455	COG0314	molybdopterin synthase activity
AMS64_13460	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AMS64_13465	COG0315	cyclic pyranopterin monophosphate synthase activity
AMS64_13470	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMS64_13475	COG3005	denitrification pathway
AMS64_13485	COG0348	domain, Protein
AMS64_13490	COG0437	4 iron, 4 sulfur cluster binding
AMS64_13495	COG0243	molybdopterin cofactor binding
AMS64_13505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMS64_13510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMS64_13515	COG3850	Histidine kinase
AMS64_13520	COG2197	response regulator
AMS64_13530	COG2205	protein histidine kinase activity
AMS64_13530	COG0784	Response regulator, receiver
AMS64_13550	COG0121	glutamine amidotransferase
AMS64_13555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMS64_13560	COG1960	acyl-CoA dehydrogenase activity
AMS64_13565	COG1473	amidohydrolase
AMS64_13575	COG2867	negative regulation of translational initiation
AMS64_13580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMS64_13585	COG0582	viral genome integration into host DNA
AMS64_13650	COG0784	Response regulator, receiver
AMS64_13650	COG2205	protein histidine kinase activity
AMS64_13660	COG3383	formate dehydrogenase (NAD+) activity
AMS64_13670	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMS64_13680	COG1960	acyl-CoA dehydrogenase activity
AMS64_13685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_13695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMS64_13795	COG0457	Tetratricopeptide repeat
AMS64_13820	COG0457	Tetratricopeptide repeat
AMS64_13865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMS64_13870	COG4790	Type iii secretion
AMS64_13875	COG4794	Type iii secretion
AMS64_13880	COG4791	protein targeting
AMS64_13915	COG1120	ATPase activity
AMS64_13920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_13925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMS64_13930	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AMS64_13935	COG4772	TonB-dependent receptor
AMS64_13965	COG0019	diaminopimelate decarboxylase activity
AMS64_13970	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMS64_13990	COG4983	Phage plasmid primase, P4 family domain protein
AMS64_14025	COG2003	Belongs to the UPF0758 family
AMS64_14105	COG0659	secondary active sulfate transmembrane transporter activity
AMS64_14155	COG0582	viral genome integration into host DNA
AMS64_14165	COG2314	TM2 domain
AMS64_14230	COG1435	thymidine kinase activity
AMS64_14235	COG1757	Na H antiporter
AMS64_14240	COG2916	Histone family protein nucleoid-structuring protein H-NS
AMS64_14245	COG2096	Adenosyltransferase
AMS64_14250	COG3530	Putative quorum-sensing-regulated virulence factor
AMS64_14255	COG0602	queuosine metabolic process
AMS64_14260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMS64_14280	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AMS64_14290	COG0776	regulation of translation
AMS64_14295	COG0539	negative regulation of cytoplasmic translation
AMS64_14300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMS64_14305	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMS64_14320	COG2814	Major facilitator Superfamily
AMS64_14340	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AMS64_14345	COG5001	Diguanylate cyclase
AMS64_14345	COG3300	MHYT domain
AMS64_14350	COG0583	DNA-binding transcription factor activity
AMS64_14355	COG3437	response regulator, receiver
AMS64_14380	COG4989	oxidoreductase activity
AMS64_14385	COG0724	RNA recognition motif
AMS64_14395	COG1126	abc transporter atp-binding protein
AMS64_14400	COG0765	amino acid transport
AMS64_14405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_14410	COG0765	amino acid transport
AMS64_14415	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AMS64_14425	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AMS64_14450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMS64_14460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_14465	COG1360	Flagellar Motor Protein
AMS64_14470	COG4771	TonB-dependent receptor
AMS64_14475	COG1770	oligopeptidase
AMS64_14495	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_14500	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_14505	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_14505	COG0649	NAD binding
AMS64_14520	COG1034	ATP synthesis coupled electron transport
AMS64_14525	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMS64_14530	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_14535	COG0839	Belongs to the complex I subunit 6 family
AMS64_14540	COG0713	ATP synthesis coupled electron transport
AMS64_14550	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMS64_14555	COG1007	ATP synthesis coupled electron transport
AMS64_14570	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_14570	COG2199	diguanylate cyclase activity
AMS64_14575	COG5001	Diguanylate cyclase
AMS64_14575	COG3300	MHYT domain
AMS64_14600	COG2050	protein possibly involved in aromatic compounds catabolism
AMS64_14610	COG0247	lactate metabolic process
AMS64_14610	COG0277	FAD linked oxidase domain protein
AMS64_14620	COG1253	flavin adenine dinucleotide binding
AMS64_14625	COG1902	pentaerythritol trinitrate reductase activity
AMS64_14635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMS64_14640	COG0647	UMP catabolic process
AMS64_14645	COG4651	solute:proton antiporter activity
AMS64_14645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMS64_14655	COG0367	asparagine synthase
AMS64_14665	COG0625	glutathione transferase activity
AMS64_14675	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AMS64_14690	COG0564	pseudouridine synthase activity
AMS64_14695	COG4160	amino acid transport
AMS64_14700	COG4215	(ABC) transporter
AMS64_14705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_14715	COG2431	L-lysine efflux transmembrane transporter activity
AMS64_14720	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMS64_14725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_14735	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AMS64_14745	COG1393	Belongs to the ArsC family
AMS64_14755	COG4783	chaperone-mediated protein folding
AMS64_14760	COG0425	Belongs to the sulfur carrier protein TusA family
AMS64_14785	COG3842	ATPase activity
AMS64_14795	COG1175	transmembrane transport
AMS64_14805	COG3081	Nucleoid-associated protein
AMS64_14810	COG3082	Protein of unknown function (DUF1414)
AMS64_14815	COG3083	sulfuric ester hydrolase activity
AMS64_14820	COG1464	Belongs to the NlpA lipoprotein family
AMS64_14835	COG0574	Belongs to the PEP-utilizing enzyme family
AMS64_14835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMS64_14840	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AMS64_14870	COG0840	transmembrane signaling receptor activity
AMS64_14930	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AMS64_14940	COG0714	Associated with various cellular activities
AMS64_14945	COG3012	SEC-C Motif Domain Protein
AMS64_14945	COG3318	Belongs to the UPF0149 family
AMS64_14960	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMS64_14960	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMS64_14965	COG0509	glycine decarboxylation via glycine cleavage system
AMS64_14970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMS64_14975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMS64_14980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMS64_14990	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AMS64_14995	COG2814	Major facilitator Superfamily
AMS64_15000	COG0625	glutathione transferase activity
AMS64_15010	COG0483	inositol monophosphate 1-phosphatase activity
AMS64_15020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AMS64_15035	COG1086	Polysaccharide biosynthesis protein
AMS64_15040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMS64_15050	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMS64_15055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMS64_15120	COG0301	tRNA thio-modification
AMS64_15120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMS64_15130	COG4953	penicillin-binding protein 1C
AMS64_15135	COG2373	Large extracellular alpha-helical protein
AMS64_15145	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_15155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMS64_15165	COG1252	NADH dehydrogenase
AMS64_15175	COG2233	PERMEase
AMS64_15185	COG2354	Protein conserved in bacteria
AMS64_15200	COG1301	dicarboxylic acid transport
AMS64_15215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMS64_15230	COG0537	adenosine 5'-monophosphoramidase activity
AMS64_15265	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_15270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMS64_15280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_15285	COG1605	Chorismate mutase
AMS64_15285	COG0287	Prephenate dehydrogenase
AMS64_15295	COG1199	ATP-dependent helicase activity
AMS64_15305	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMS64_15310	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AMS64_15315	COG1785	Belongs to the alkaline phosphatase family
AMS64_15335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMS64_15340	COG2197	response regulator
AMS64_15350	COG2271	Major facilitator Superfamily
AMS64_15355	COG2203	Gaf domain
AMS64_15355	COG2199	diguanylate cyclase activity
AMS64_15360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_15365	COG0765	amino acid transport
AMS64_15370	COG1126	abc transporter atp-binding protein
AMS64_15385	COG0531	amino acid
AMS64_15400	COG1253	flavin adenine dinucleotide binding
AMS64_15405	COG0704	Plays a role in the regulation of phosphate uptake
AMS64_15415	COG0581	inorganic phosphate transmembrane transporter activity
AMS64_15420	COG0573	inorganic phosphate transmembrane transporter activity
AMS64_15425	COG0590	tRNA wobble adenosine to inosine editing
AMS64_15435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMS64_15455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMS64_15460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMS64_15465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMS64_15600	COG4695	Portal protein
AMS64_15705	COG4974	Belongs to the 'phage' integrase family
AMS64_15710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMS64_15715	COG2204	response regulator
AMS64_15720	COG3852	Histidine kinase
AMS64_15725	COG2204	response regulator
AMS64_15735	COG2716	regulation of RNA biosynthetic process
AMS64_15740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMS64_15745	COG0248	Ppx GppA phosphatase
AMS64_15750	COG2239	Acts as a magnesium transporter
AMS64_15755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMS64_15765	COG3951	Flagellar rod assembly protein muramidase FlgJ
AMS64_15765	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMS64_15770	COG1706	bacterial-type flagellum-dependent cell motility
AMS64_15775	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMS64_15780	COG4786	Flagellar basal body rod
AMS64_15785	COG4787	bacterial-type flagellum-dependent cell motility
AMS64_15795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AMS64_15800	COG1558	bacterial-type flagellum-dependent cell motility
AMS64_15805	COG1815	bacterial-type flagellum-dependent cell motility
AMS64_15810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMS64_15815	COG0784	Response regulator, receiver
AMS64_15815	COG0835	chemotaxis
AMS64_15820	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
AMS64_15835	COG0622	Phosphoesterase
AMS64_15840	COG4166	transmembrane transport
AMS64_15850	COG1187	pseudouridine synthase activity
AMS64_15855	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_15865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMS64_15870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMS64_15880	COG1349	DNA-binding transcription factor activity
AMS64_15885	COG4166	transmembrane transport
AMS64_15910	COG1278	Cold shock
AMS64_15935	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AMS64_15935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMS64_15940	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_15945	COG3433	isochorismatase activity
AMS64_15945	COG1535	isochorismatase
AMS64_15950	COG1021	2,3-dihydroxybenzoate-AMP ligase
AMS64_15955	COG1169	isochorismate synthase
AMS64_15960	COG4771	TonB-dependent receptor
AMS64_15965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMS64_15970	COG1609	Transcriptional regulator
AMS64_15975	COG0741	lytic transglycosylase activity
AMS64_15985	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMS64_16005	COG2911	Protein conserved in bacteria
AMS64_16010	COG0729	surface antigen
AMS64_16020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMS64_16030	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMS64_16040	COG4134	Bacterial extracellular solute-binding protein
AMS64_16050	COG4136	ATPase activity
AMS64_16055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMS64_16060	COG2951	lytic endotransglycosylase activity
AMS64_16065	COG0033	Phosphoglucomutase
AMS64_16070	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AMS64_16075	COG0596	Alpha beta hydrolase
AMS64_16090	COG0716	FMN binding
AMS64_16100	COG0735	belongs to the Fur family
AMS64_16105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_16115	COG1263	PTS System
AMS64_16115	COG2190	(PTS) system
AMS64_16115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_16120	COG0363	glucosamine-6-phosphate deaminase activity
AMS64_16125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AMS64_16130	COG1846	Transcriptional regulator
AMS64_16130	COG1940	carbohydrate kinase activity
AMS64_16140	COG2199	diguanylate cyclase activity
AMS64_16140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMS64_16145	COG3275	phosphorelay sensor kinase activity
AMS64_16150	COG3279	Response regulator of the LytR AlgR family
AMS64_16155	COG1966	Carbon starvation protein
AMS64_16165	COG1566	PFAM secretion protein HlyD family protein
AMS64_16170	COG1061	Type III restriction enzyme res subunit
AMS64_16175	COG2027	D-alanyl-D-alanine carboxypeptidase
AMS64_16180	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AMS64_16185	COG3021	interspecies interaction between organisms
AMS64_16195	COG1607	acyl-coa hydrolase
AMS64_16200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMS64_16210	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMS64_16210	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMS64_16210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AMS64_16210	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMS64_16225	COG3217	Mosc domain protein beta barrel domain protein
AMS64_16225	COG3217	Mosc domain protein beta barrel domain protein
AMS64_16225	COG0633	Ferredoxin
AMS64_16225	COG0633	Ferredoxin
AMS64_16235	COG0501	Belongs to the peptidase M48B family
AMS64_16240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMS64_16245	COG1073	alpha beta
AMS64_16245	COG2226	methyltransferase
AMS64_16250	COG0156	8-amino-7-oxononanoate synthase activity
AMS64_16255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMS64_16260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMS64_16275	COG0017	Asparaginyl-tRNA synthetase
AMS64_16285	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMS64_16300	COG1393	Belongs to the ArsC family
AMS64_16305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMS64_16310	COG1876	peptidase activity
AMS64_16315	COG3263	regulation of cellular component size
AMS64_16330	COG1280	lysine exporter protein (LysE YggA)
AMS64_16360	COG1957	nucleoside hydrolase
AMS64_16365	COG0564	pseudouridine synthase activity
AMS64_16375	COG1454	alcohol dehydrogenase
AMS64_16380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMS64_16385	COG0702	epimerase
AMS64_16395	COG0095	Lipoate-protein ligase
AMS64_16405	COG0577	efflux transmembrane transporter activity
AMS64_16405	COG1136	(ABC) transporter
AMS64_16410	COG0577	efflux transmembrane transporter activity
AMS64_16410	COG1136	(ABC) transporter
AMS64_16415	COG1136	(ABC) transporter
AMS64_16415	COG0577	efflux transmembrane transporter activity
AMS64_16420	COG1566	PFAM secretion protein HlyD family protein
AMS64_16455	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_16465	COG1285	pathogenesis
AMS64_16495	COG0484	heat shock protein binding
AMS64_16500	COG0443	Heat shock 70 kDa protein
AMS64_16505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMS64_16510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMS64_16515	COG0497	DNA recombination
AMS64_16520	COG1227	inorganic diphosphatase activity
AMS64_16525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_16530	COG1136	(ABC) transporter
AMS64_16530	COG0577	efflux transmembrane transporter activity
AMS64_16535	COG1538	Outer membrane efflux protein
AMS64_16555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMS64_16565	COG0297	glycogen (starch) synthase activity
AMS64_16570	COG0463	Glycosyl transferase, family 2
AMS64_16570	COG1216	Glycosyl transferase, family 2
AMS64_16585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMS64_16600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMS64_16600	COG2755	lipolytic protein G-D-S-L family
AMS64_16680	COG1459	type II secretion system
AMS64_16700	COG1091	dTDP-4-dehydrorhamnose reductase activity
AMS64_16710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMS64_16715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_16720	COG1309	transcriptional regulator
AMS64_16735	COG1342	Belongs to the UPF0251 family
AMS64_16755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMS64_16805	COG0813	purine-nucleoside phosphorylase activity
AMS64_16815	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMS64_16820	COG0083	homoserine kinase activity
AMS64_16830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AMS64_16835	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AMS64_16840	COG1946	Acyl-CoA thioesterase
AMS64_16855	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMS64_16865	COG0009	L-threonylcarbamoyladenylate synthase
AMS64_16875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMS64_16880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMS64_16880	COG0512	Glutamine amidotransferase of anthranilate synthase
AMS64_16885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMS64_16890	COG0135	phosphoribosylanthranilate isomerase activity
AMS64_16890	COG0134	indole-3-glycerol-phosphate synthase activity
AMS64_16895	COG0133	tryptophan synthase activity
AMS64_16900	COG0159	tryptophan synthase activity
AMS64_16910	COG1988	membrane-bound metal-dependent
AMS64_16925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_16935	COG0798	PFAM Bile acid sodium symporter
AMS64_16965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMS64_16975	COG0745	RESPONSE REGULATOR receiver
AMS64_16990	COG4988	ABC transporter
AMS64_16995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AMS64_17015	COG1720	tRNA m6t6A37 methyltransferase activity
AMS64_17020	COG3038	cytochrome b561
AMS64_17030	COG0745	RESPONSE REGULATOR receiver
AMS64_17040	COG2862	Uncharacterized protein family, UPF0114
AMS64_17055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMS64_17060	COG1396	sequence-specific DNA binding
AMS64_17060	COG1917	Cupin 2, conserved barrel domain protein
AMS64_17075	COG0531	amino acid
AMS64_17090	COG0531	amino acid
AMS64_17095	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMS64_17110	COG2974	May be involved in recombination
AMS64_17120	COG0420	3'-5' exonuclease activity
AMS64_17125	COG0419	ATPase involved in DNA repair
AMS64_17130	COG3384	dioxygenase
AMS64_17140	COG0469	pyruvate kinase activity
AMS64_17145	COG3264	Mechanosensitive ion channel
AMS64_17145	COG1196	nuclear chromosome segregation
AMS64_17155	COG3590	peptidase
AMS64_17160	COG3706	GGDEF domain
AMS64_17165	COG2190	(PTS) system
AMS64_17175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMS64_17180	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMS64_17185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMS64_17200	COG2770	Histidine kinase
AMS64_17200	COG3437	response regulator, receiver
AMS64_17205	COG3267	Type II secretory pathway component ExeA
AMS64_17205	COG3409	Peptidoglycan-binding domain 1 protein
AMS64_17215	COG3031	protein transport across the cell outer membrane
AMS64_17225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMS64_17230	COG1459	type II secretion system
AMS64_17235	COG2165	general secretion pathway protein
AMS64_17245	COG2165	general secretion pathway protein
AMS64_17250	COG4795	General secretion pathway protein
AMS64_17255	COG3156	type II secretion system protein K
AMS64_17265	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AMS64_17280	COG0670	Belongs to the BI1 family
AMS64_17285	COG1289	transmembrane transporter activity
AMS64_17290	COG2920	part of a sulfur-relay system
AMS64_17295	COG0673	inositol 2-dehydrogenase activity
AMS64_17300	COG0583	DNA-binding transcription factor activity
AMS64_17340	COG1032	radical SAM domain protein
AMS64_17350	COG1566	PFAM secretion protein HlyD family protein
AMS64_17355	COG3706	GGDEF domain
AMS64_17360	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMS64_17395	COG0531	amino acid
AMS64_17425	COG0281	malic enzyme
AMS64_17435	COG0534	Mate efflux family protein
AMS64_17445	COG3706	GGDEF domain
AMS64_17450	COG2233	PERMEase
AMS64_17455	COG0095	Lipoate-protein ligase
AMS64_17460	COG1115	amino acid carrier protein
AMS64_17465	COG0019	diaminopimelate decarboxylase activity
AMS64_17475	COG0678	peroxiredoxin activity
AMS64_17500	COG0545	Peptidyl-prolyl cis-trans isomerase
AMS64_17505	COG3142	Participates in the control of copper homeostasis
AMS64_17520	COG4783	chaperone-mediated protein folding
AMS64_17530	COG5002	protein histidine kinase activity
AMS64_17535	COG0745	RESPONSE REGULATOR receiver
AMS64_17540	COG0346	lactoylglutathione lyase activity
AMS64_17545	COG3284	Transcriptional regulator
AMS64_17550	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_17560	COG0697	spore germination
AMS64_17570	COG3290	protein histidine kinase activity
AMS64_17575	COG0281	malic enzyme
AMS64_17585	COG1846	Transcriptional regulator
AMS64_17590	COG1566	PFAM secretion protein HlyD family protein
AMS64_17615	COG0602	queuosine metabolic process
AMS64_17620	COG1328	CTP reductase activity
AMS64_17630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMS64_17635	COG3115	cell septum assembly
AMS64_17640	COG1196	nuclear chromosome segregation
AMS64_17650	COG2860	membrane
AMS64_17660	COG3108	Peptidase M15
AMS64_17665	COG2989	Protein conserved in bacteria
AMS64_17680	COG0463	Glycosyl transferase, family 2
AMS64_17695	COG0366	Alpha amylase catalytic
AMS64_17730	COG2199	diguanylate cyclase activity
AMS64_17730	COG2203	Gaf domain
AMS64_17740	COG3590	peptidase
AMS64_17755	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AMS64_17760	COG1982	Orn Lys Arg decarboxylase major
AMS64_17765	COG0531	amino acid
AMS64_17770	COG3710	Transcriptional regulator
AMS64_17775	COG0531	amino acid
AMS64_17795	COG0814	amino acid
AMS64_17825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMS64_17830	COG0739	heme binding
AMS64_17835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMS64_17845	COG0251	oxidation-reduction process
AMS64_17860	COG0583	DNA-binding transcription factor activity
AMS64_17875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMS64_17885	COG3091	SprT-like family
AMS64_17895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMS64_17900	COG0189	ligase activity
AMS64_17905	COG1678	Uncharacterized ACR, COG1678
AMS64_17910	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AMS64_17915	COG3104	oligopeptide transport
AMS64_17920	COG0583	DNA-binding transcription factor activity
AMS64_17930	COG0714	Associated with various cellular activities
AMS64_17945	COG1115	amino acid carrier protein
AMS64_17950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMS64_17960	COG0825	malonyl-CoA metabolic process
AMS64_17970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMS64_17975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_17980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_17985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AMS64_17990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMS64_18005	COG0750	zinc metalloprotease
AMS64_18010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMS64_18015	COG0575	Belongs to the CDS family
AMS64_18025	COG0233	cytoplasmic translational termination
AMS64_18030	COG0528	UMP kinase activity
AMS64_18035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMS64_18040	COG0052	Belongs to the universal ribosomal protein uS2 family
AMS64_18045	COG0024	Methionine aminopeptidase
AMS64_18050	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMS64_18055	COG2171	N-acyltransferase activity
AMS64_18065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_18065	COG1263	PTS System
AMS64_18075	COG4580	involved in the transport of maltose and maltodextrins
AMS64_18085	COG0564	pseudouridine synthase activity
AMS64_18090	COG3098	single-species biofilm formation
AMS64_18115	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AMS64_18125	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMS64_18125	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMS64_18135	COG3706	GGDEF domain
AMS64_18140	COG1611	Belongs to the LOG family
AMS64_18145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AMS64_18150	COG0473	3-isopropylmalate dehydrogenase activity
AMS64_18160	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
AMS64_18165	COG2363	Small membrane protein
AMS64_18175	COG0583	DNA-binding transcription factor activity
AMS64_18180	COG0840	transmembrane signaling receptor activity
AMS64_18185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMS64_18200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMS64_18205	COG1666	GTP binding
AMS64_18210	COG3248	Nucleoside-binding outer membrane protein
AMS64_18215	COG2211	Major facilitator Superfamily
AMS64_18220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMS64_18230	COG2813	Specifically methylates the guanine in position
AMS64_18235	COG0271	Belongs to the BolA IbaG family
AMS64_18240	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_18245	COG1805	sodium ion transport
AMS64_18255	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_18260	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AMS64_18265	COG2871	sodium ion transport
AMS64_18270	COG1477	protein flavinylation
AMS64_18300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMS64_18315	COG0300	oxidoreductase activity
AMS64_18325	COG0415	Belongs to the DNA photolyase family
AMS64_18330	COG0789	Transcriptional regulator
AMS64_18335	COG3272	Protein of unknown function (DUF1722)
AMS64_18365	COG0077	Prephenate dehydratase
AMS64_18365	COG1605	Chorismate mutase
AMS64_18395	COG5377	YqaJ viral recombinase family
AMS64_18440	COG2003	Belongs to the UPF0758 family
AMS64_18530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMS64_18610	COG0300	oxidoreductase activity
AMS64_18635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AMS64_18675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMS64_18680	COG0826	peptidase U32
AMS64_18685	COG1280	lysine exporter protein (LysE YggA)
AMS64_18715	COG2198	Histidine kinase
AMS64_18715	COG0643	Histidine kinase
AMS64_18725	COG0835	chemotaxis
AMS64_18730	COG0840	transmembrane signaling receptor activity
AMS64_18740	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMS64_18745	COG2201	protein-glutamate methylesterase activity
AMS64_18750	COG1185	polyribonucleotide nucleotidyltransferase activity
AMS64_18755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMS64_18760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMS64_18765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMS64_18770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AMS64_18775	COG0195	Participates in both transcription termination and antitermination
AMS64_18780	COG0779	Required for maturation of 30S ribosomal subunits
AMS64_18795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMS64_18800	COG0149	triose-phosphate isomerase activity
AMS64_18805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMS64_18810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMS64_18815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMS64_18820	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMS64_18825	COG1534	Rna-binding protein
AMS64_18835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMS64_18840	COG1360	Flagellar Motor Protein
AMS64_18845	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMS64_18850	COG1722	exodeoxyribonuclease VII activity
AMS64_18855	COG0142	geranyltranstransferase activity
AMS64_18860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMS64_18885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AMS64_18890	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AMS64_18895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMS64_18900	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMS64_18920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMS64_18920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMS64_18925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMS64_18930	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMS64_18940	COG0784	Response regulator, receiver
AMS64_18940	COG2198	Histidine kinase
AMS64_18940	COG2205	protein histidine kinase activity
AMS64_18945	COG1879	ABC-type sugar transport system periplasmic component
AMS64_18955	COG0745	RESPONSE REGULATOR receiver
AMS64_18960	COG3005	denitrification pathway
AMS64_18970	COG3381	protein complex oligomerization
AMS64_18990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMS64_18995	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMS64_19000	COG0511	ligase activity, forming carbon-carbon bonds
AMS64_19005	COG0439	Biotin carboxylase
AMS64_19015	COG4145	pantothenate transmembrane transporter activity
AMS64_19020	COG1263	PTS System
AMS64_19020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMS64_19020	COG2190	(PTS) system
AMS64_19025	COG0583	DNA-binding transcription factor activity
AMS64_19030	COG0604	alcohol dehydrogenase
AMS64_19035	COG2264	protein methyltransferase activity
AMS64_19045	COG0778	Nitroreductase
AMS64_19050	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_19050	COG1902	pentaerythritol trinitrate reductase activity
AMS64_19055	COG0616	signal peptide processing
AMS64_19075	COG0848	biopolymer transport protein
AMS64_19080	COG0811	peptide transport
AMS64_19085	COG0811	peptide transport
AMS64_19100	COG4174	ABC transporter (Permease)
AMS64_19105	COG4239	(ABC) transporter, permease
AMS64_19115	COG0444	Belongs to the ABC transporter superfamily
AMS64_19120	COG4608	Belongs to the ABC transporter superfamily
AMS64_19140	COG3416	Protein conserved in bacteria
AMS64_19170	COG0488	(ABC) transporter
AMS64_19180	COG2252	PERMEase
AMS64_19185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_19190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMS64_19195	COG0840	transmembrane signaling receptor activity
AMS64_19205	COG1278	Cold shock
AMS64_19245	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMS64_19250	COG1162	GTPase activity
AMS64_19255	COG0688	phosphatidylethanolamine metabolic process
AMS64_19260	COG4628	conserved protein (DUF2132)
AMS64_19275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMS64_19295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMS64_19300	COG2195	Cleaves the N-terminal amino acid of tripeptides
AMS64_19305	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AMS64_19310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMS64_19315	COG3178	'Phosphotransferase
AMS64_19320	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AMS64_19325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMS64_19330	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMS64_19335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMS64_19345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMS64_19360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMS64_19375	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMS64_19380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMS64_19390	COG0142	geranyltranstransferase activity
AMS64_19395	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AMS64_19400	COG0330	HflC and HflK could
AMS64_19405	COG0330	HflC and HflK could
AMS64_19410	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMS64_19415	COG1923	regulation of RNA biosynthetic process
AMS64_19420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMS64_19425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMS64_19430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMS64_19440	COG0802	atpase or kinase
AMS64_19445	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMS64_19445	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMS64_19465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMS64_19470	COG2011	ABC-type metal ion transport system permease component
AMS64_19475	COG1464	Belongs to the NlpA lipoprotein family
AMS64_19495	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMS64_19500	COG0784	Response regulator, receiver
AMS64_19500	COG2198	Histidine kinase
AMS64_19500	COG5002	protein histidine kinase activity
AMS64_19535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMS64_19540	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AMS64_19545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMS64_19550	COG2716	regulation of RNA biosynthetic process
AMS64_19555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMS64_19560	COG3013	Belongs to the UPF0304 family
AMS64_19565	COG3092	negative regulation of chromosome organization
AMS64_19570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMS64_19575	COG0857	belongs to the CobB CobQ family
AMS64_19575	COG0280	phosphate acetyltransferase
AMS64_19580	COG1555	photosystem II stabilization
AMS64_19585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMS64_19590	COG3104	oligopeptide transport
AMS64_19595	COG0745	RESPONSE REGULATOR receiver
AMS64_19625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMS64_19640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AMS64_19660	COG0440	acetolactate synthase activity
AMS64_19665	COG0028	Belongs to the TPP enzyme family
AMS64_19685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMS64_19690	COG0473	3-isopropylmalate dehydrogenase activity
AMS64_19695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMS64_19700	COG0066	3-isopropylmalate dehydratase activity
AMS64_19715	COG4143	(ABC) transporter
AMS64_19720	COG1178	ABC-type Fe3 transport system permease component
AMS64_19725	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AMS64_19730	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMS64_19780	COG0459	protein refolding
AMS64_19785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMS64_19795	COG3030	protein affecting phage T7 exclusion by the F plasmid
AMS64_19800	COG1027	Aspartate ammonia-lyase
AMS64_19805	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMS64_19810	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMS64_19815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMS64_19820	COG1610	YqeY-like protein
AMS64_19825	COG0358	DNA primase activity
AMS64_19830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMS64_19850	COG0151	Belongs to the GarS family
AMS64_19855	COG0138	bifunctional purine biosynthesis protein purh
AMS64_19865	COG3036	rescue of stalled ribosome
AMS64_19875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMS64_19880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMS64_19890	COG0673	inositol 2-dehydrogenase activity
AMS64_19900	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMS64_19905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMS64_19915	COG0583	DNA-binding transcription factor activity
AMS64_19920	COG0477	Major facilitator Superfamily
AMS64_19935	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_19940	COG0745	RESPONSE REGULATOR receiver
AMS64_19940	COG3706	GGDEF domain
AMS64_19945	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AMS64_19950	COG0714	Associated with various cellular activities
AMS64_19960	COG0456	acetyltransferase
AMS64_19970	COG1022	Amp-dependent synthetase and ligase
AMS64_19975	COG2918	glutathione biosynthetic process
AMS64_19980	COG0612	Peptidase, M16
AMS64_19985	COG1238	metal cluster binding
AMS64_19990	COG1064	alcohol dehydrogenase
AMS64_20010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_20015	COG0359	binds to the 23S rRNA
AMS64_20020	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMS64_20025	COG0360	Binds together with S18 to 16S ribosomal RNA
AMS64_20030	COG1914	H( )-stimulated, divalent metal cation uptake system
AMS64_20035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMS64_20045	COG0776	regulation of translation
AMS64_20060	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMS64_20075	COG0560	Phosphoserine phosphatase
AMS64_20085	COG0813	purine-nucleoside phosphorylase activity
AMS64_20090	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AMS64_20095	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AMS64_20100	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMS64_20110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_20115	COG0084	hydrolase, TatD family'
AMS64_20120	COG4968	Prepilin-type N-terminal cleavage methylation domain
AMS64_20125	COG1854	S-ribosylhomocysteine lyase activity
AMS64_20140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMS64_20140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMS64_20175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMS64_20180	COG1047	Peptidyl-prolyl cis-trans
AMS64_20185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMS64_20190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMS64_20195	COG0196	riboflavin kinase activity
AMS64_20200	COG0728	peptidoglycan biosynthetic process
AMS64_20205	COG0268	Binds directly to 16S ribosomal RNA
AMS64_20210	COG0640	Transcriptional regulator
AMS64_20215	COG0583	DNA-binding transcription factor activity
AMS64_20225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMS64_20230	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AMS64_20235	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMS64_20240	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AMS64_20245	COG1051	belongs to the nudix hydrolase family
AMS64_20250	COG3066	DNA modification
AMS64_20260	COG0335	large ribosomal subunit rRNA binding
AMS64_20265	COG0336	Belongs to the RNA methyltransferase TrmD family
AMS64_20270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMS64_20275	COG0228	four-way junction DNA binding
AMS64_20280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMS64_20285	COG4137	Cytochrome C assembly protein
AMS64_20290	COG4536	flavin adenine dinucleotide binding
AMS64_20300	COG1017	nitric oxide dioxygenase activity
AMS64_20300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMS64_20305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AMS64_20310	COG0039	L-malate dehydrogenase activity
AMS64_20315	COG4160	amino acid transport
AMS64_20320	COG4215	(ABC) transporter
AMS64_20325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_20330	COG1126	abc transporter atp-binding protein
AMS64_20335	COG1438	arginine binding
AMS64_20340	COG2837	iron assimilation
AMS64_20345	COG3842	ATPase activity
AMS64_20355	COG1840	ABC-type Fe3 transport system, periplasmic component
AMS64_20360	COG0347	Belongs to the P(II) protein family
AMS64_20380	COG3022	response to hydroperoxide
AMS64_20395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMS64_20400	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMS64_20405	COG0762	integral membrane protein
AMS64_20410	COG1872	DUF167
AMS64_20420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AMS64_20425	COG0583	DNA-binding transcription factor activity
AMS64_20440	COG1929	Belongs to the glycerate kinase type-1 family
AMS64_20445	COG2610	gluconate transmembrane transporter activity
AMS64_20450	COG3835	regulator
AMS64_20455	COG3112	Uncharacterised protein family (UPF0231)
AMS64_20475	COG3568	Endonuclease Exonuclease Phosphatase
AMS64_20485	COG0513	Belongs to the DEAD box helicase family
AMS64_20525	COG1448	Aminotransferase
AMS64_20530	COG0583	DNA-binding transcription factor activity
AMS64_20540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMS64_20545	COG1328	CTP reductase activity
AMS64_20570	COG0633	Ferredoxin
AMS64_20570	COG0543	2 iron, 2 sulfur cluster binding
AMS64_20585	COG1215	transferase activity, transferring glycosyl groups
AMS64_20590	COG0726	polysaccharide deacetylase
AMS64_20590	COG1649	PFAM Uncharacterised BCR, COG1649
AMS64_20605	COG4783	chaperone-mediated protein folding
AMS64_20610	COG1215	transferase activity, transferring glycosyl groups
AMS64_20625	COG0840	transmembrane signaling receptor activity
AMS64_20630	COG3397	chitin binding
AMS64_20635	COG0583	DNA-binding transcription factor activity
AMS64_20640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMS64_20645	COG4208	sulfate ABC transporter
AMS64_20650	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AMS64_20660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AMS64_20665	COG3174	membrane
AMS64_20670	COG0110	maltose O-acetyltransferase activity
AMS64_20685	COG1011	Hydrolase
AMS64_20690	COG0494	nUDIX hydrolase
AMS64_20695	COG1218	3'(2'),5'-bisphosphate nucleotidase
AMS64_20700	COG0814	amino acid
AMS64_20705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMS64_20720	COG0626	cystathionine gamma-synthase activity
AMS64_20725	COG0460	homoserine dehydrogenase
AMS64_20725	COG0527	aspartate kinase activity
AMS64_20730	COG0306	phosphate transporter
AMS64_20735	COG1392	Phosphate transport regulator
AMS64_20745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMS64_20750	COG2813	Specifically methylates the guanine in position
AMS64_20755	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMS64_20760	COG0297	glycogen (starch) synthase activity
AMS64_20810	COG1757	Na H antiporter
AMS64_20815	COG0316	Belongs to the HesB IscA family
AMS64_20825	COG0038	chloride channel
AMS64_20830	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMS64_20845	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMS64_20845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMS64_20880	COG1396	sequence-specific DNA binding
AMS64_20885	COG3135	benzoate transporter
AMS64_20910	COG0840	transmembrane signaling receptor activity
AMS64_20915	COG3047	cAMP biosynthetic process
AMS64_20920	COG3706	GGDEF domain
AMS64_20925	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMS64_20945	COG1462	curli production assembly transport component CsgG
AMS64_20960	COG2197	response regulator
AMS64_20985	COG1278	Cold shock
AMS64_20990	COG2252	PERMEase
AMS64_20995	COG2376	Dihydroxyacetone kinase
AMS64_21000	COG1461	Dihydroxyacetone kinase
AMS64_21015	COG3284	Transcriptional regulator
AMS64_21025	COG0628	permease
AMS64_21030	COG0494	nUDIX hydrolase
AMS64_21045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMS64_21070	COG0456	acetyltransferase
AMS64_21075	COG3133	Outer membrane lipoprotein
AMS64_21080	COG0004	ammonium transporteR
AMS64_21085	COG3706	GGDEF domain
AMS64_21095	COG3932	Exopolysaccharide synthesis, ExoD
AMS64_21100	COG0814	amino acid
AMS64_21105	COG3706	GGDEF domain
AMS64_21115	COG0110	maltose O-acetyltransferase activity
AMS64_21135	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMS64_21140	COG2022	thiamine diphosphate biosynthetic process
AMS64_21150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMS64_21155	COG0352	thiamine-phosphate diphosphorylase activity
AMS64_21160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMS64_21185	COG0745	RESPONSE REGULATOR receiver
AMS64_21195	COG0189	ligase activity
AMS64_21210	COG0582	viral genome integration into host DNA
AMS64_21235	COG1715	Restriction endonuclease
AMS64_21245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AMS64_21300	COG0477	Major facilitator Superfamily
AMS64_21315	COG0312	modulator of DNA gyrase
AMS64_21320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMS64_21330	COG3164	Protein of unknown function
AMS64_21335	COG1530	ribonuclease E activity
AMS64_21340	COG0424	maF-like protein
AMS64_21345	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AMS64_21350	COG1792	Involved in formation and maintenance of cell shape
AMS64_21355	COG1077	Cell shape determining protein MreB Mrl
AMS64_21380	COG4968	Prepilin-type N-terminal cleavage methylation domain
AMS64_21385	COG4969	Belongs to the N-Me-Phe pilin family
AMS64_21400	COG1459	type II secretion system
AMS64_21405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMS64_21450	COG2199	diguanylate cyclase activity
AMS64_21450	COG2200	EAL domain
AMS64_21455	COG2200	EAL domain
AMS64_21460	COG0387	Pfam Sodium calcium exchanger
AMS64_21465	COG2986	histidine ammonia-lyase
AMS64_21470	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMS64_21475	COG0010	Belongs to the arginase family
AMS64_21480	COG1228	amidohydrolase
AMS64_21485	COG2188	Transcriptional regulator
AMS64_21490	COG0288	reversible hydration of carbon dioxide
AMS64_21500	COG2177	Part of the ABC transporter FtsEX involved in
AMS64_21505	COG2884	Cell division ATP-binding protein ftsE
AMS64_21510	COG0552	protein localization to endoplasmic reticulum
AMS64_21515	COG0742	ribosomal rna small subunit methyltransferase
AMS64_21540	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMS64_21550	COG4221	oxidoreductase activity
AMS64_21565	COG1770	oligopeptidase
AMS64_21580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMS64_21585	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AMS64_21595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMS64_21605	COG2095	MarC family integral membrane protein
AMS64_21615	COG1301	dicarboxylic acid transport
AMS64_21640	COG3714	YhhN family
AMS64_21685	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMS64_21690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMS64_21695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMS64_21700	COG0049	tRNA binding
AMS64_21710	COG2168	tRNA wobble position uridine thiolation
AMS64_21715	COG2923	Belongs to the DsrF TusC family
AMS64_21720	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AMS64_21730	COG2964	Protein conserved in bacteria
AMS64_21735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMS64_21740	COG0085	RNA polymerase activity
AMS64_21745	COG0222	ribosome binding
AMS64_21750	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMS64_21755	COG0081	regulation of translation
AMS64_21760	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMS64_21765	COG0250	Participates in transcription elongation, termination and antitermination
AMS64_21770	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AMS64_21780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMS64_21805	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMS64_21810	COG0569	domain protein
AMS64_21815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMS64_21845	COG4191	Histidine kinase
AMS64_21845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMS64_21850	COG3005	denitrification pathway
AMS64_21855	COG0243	molybdopterin cofactor binding
AMS64_21865	COG2205	protein histidine kinase activity
AMS64_21870	COG0745	RESPONSE REGULATOR receiver
AMS64_21900	COG2204	response regulator
AMS64_21910	COG2205	protein histidine kinase activity
AMS64_21920	COG1028	Short-chain dehydrogenase reductase Sdr
AMS64_21925	COG0517	IMP dehydrogenase activity
AMS64_21930	COG5413	integral membrane protein
AMS64_21940	COG1522	sequence-specific DNA binding
AMS64_21945	COG2502	aspartate--ammonia ligase
AMS64_21950	COG0542	response to heat
AMS64_21960	COG0564	pseudouridine synthase activity
AMS64_21965	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMS64_21970	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMS64_21980	COG3681	Belongs to the UPF0597 family
AMS64_21985	COG2964	Protein conserved in bacteria
AMS64_21995	COG4974	Belongs to the 'phage' integrase family
AMS64_22010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMS64_22175	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AMS64_22180	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMS64_22185	COG1979	alcohol dehydrogenase
AMS64_22190	COG2207	Transcriptional regulator
AMS64_22210	COG0583	DNA-binding transcription factor activity
AMS64_22225	COG0540	Belongs to the ATCase OTCase family
AMS64_22230	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AMS64_22235	COG1438	arginine binding
AMS64_22240	COG1288	antiporter activity
AMS64_22245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMS64_22270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMS64_22280	COG3078	GTPase activator activity
AMS64_22295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AMS64_22305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMS64_22310	COG0408	coproporphyrinogen oxidase activity
AMS64_22315	COG0009	L-threonylcarbamoyladenylate synthase
AMS64_22325	COG0551	DNA topoisomerase type I activity
AMS64_22330	COG2922	Belongs to the Smg family
AMS64_22335	COG0758	DNA mediated transformation
AMS64_22340	COG1652	LysM domain
AMS64_22345	COG0242	peptide deformylase activity
AMS64_22350	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMS64_22355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMS64_22355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMS64_22360	COG0569	domain protein
AMS64_22365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AMS64_22375	COG0174	glutamine synthetase
AMS64_22385	COG3852	Histidine kinase
AMS64_22390	COG2204	response regulator
AMS64_22395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMS64_22400	COG1322	Protein conserved in bacteria
AMS64_22425	COG0583	DNA-binding transcription factor activity
AMS64_22430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMS64_22430	COG0519	Catalyzes the synthesis of GMP from XMP
AMS64_22445	COG1396	sequence-specific DNA binding
AMS64_22450	COG1012	belongs to the aldehyde dehydrogenase family
AMS64_22455	COG2962	Rard protein
AMS64_22465	COG2391	methyltransferase activity
AMS64_22480	COG0129	dihydroxy-acid dehydratase activity
AMS64_22485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMS64_22490	COG3978	acetolactate synthase activity
AMS64_22510	COG0210	DNA helicase
AMS64_22575	COG0204	Acyl-transferase
AMS64_22580	COG0204	Acyl-transferase
AMS64_22585	COG1683	Conserved Protein
AMS64_22595	COG1335	isochorismatase
AMS64_22605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMS64_22610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMS64_22620	COG3084	Protein conserved in bacteria