locus-tag	class	description
WP2S18C03_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
WP2S18C03_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
WP2S18C03_00030	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
WP2S18C03_00040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WP2S18C03_00070	ENOG4105D29	Helix-turn-helix type 11 domain protein
WP2S18C03_00080	ENOG4105ECQ	AraC Family Transcriptional Regulator
WP2S18C03_00090	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
WP2S18C03_00100	ENOG4108ZNX	Heat shock protein
WP2S18C03_00120	ENOG4105F5W	AtP-binding protein
WP2S18C03_00130	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_00140	ENOG4108ZNX	Heat shock protein
WP2S18C03_00150	ENOG4105JKW	Valine--pyruvate aminotransferase
WP2S18C03_00170	ENOG4105C2C	drug resistance transporter, Bcr CflA
WP2S18C03_00180	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
WP2S18C03_00190	ENOG4105C08	Histidine kinase
WP2S18C03_00200	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
WP2S18C03_00210	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
WP2S18C03_00220	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
WP2S18C03_00230	ENOG4105DC8	reductase
WP2S18C03_00240	ENOG4105BZU	Histidine kinase
WP2S18C03_00250	ENOG4105BZS	acriflavin resistance protein
WP2S18C03_00260	ENOG410624X	efflux transporter, rnd family, mfp subunit
WP2S18C03_00270	ENOG4105Y7M	Transcriptional regulator, TetR family
WP2S18C03_00290	ENOG4105F5W	AtP-binding protein
WP2S18C03_00300	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_00330	ENOG4105DQF	Hydrolase
WP2S18C03_00340	ENOG4108EUD	Lysophospholipase
WP2S18C03_00360	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
WP2S18C03_00370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
WP2S18C03_00380	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
WP2S18C03_00390	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
WP2S18C03_00400	ENOG4105DKP	glycosyl transferase, family 9
WP2S18C03_00410	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
WP2S18C03_00430	ENOG4105EMK	carboxylate amino acid amine transporter
WP2S18C03_00490	ENOG4108M6U	Universal stress protein A
WP2S18C03_00500	ENOG4105RKW	reductase (By
WP2S18C03_00510	ENOG41090A1	ferritin
WP2S18C03_00520	ENOG4105CBX	hi0933 family
WP2S18C03_00530	ENOG4108HRK	Histidine kinase
WP2S18C03_00540	ENOG4105DY9	regulatoR
WP2S18C03_00550	ENOG4105FCD	Major Facilitator
WP2S18C03_00560	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
WP2S18C03_00570	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
WP2S18C03_00600	ENOG41063Z6	transcriptional regulator, lysR family
WP2S18C03_00610	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
WP2S18C03_00620	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
WP2S18C03_00650	ENOG4105CUZ	uba thif-type nad fad binding protein
WP2S18C03_00660	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
WP2S18C03_00670	ENOG4105C9B	Cysteine desulfurase
WP2S18C03_00680	ENOG4105C4R	Atp-dependent dna helicase
WP2S18C03_00690	ENOG4105BZU	Histidine kinase
WP2S18C03_00700	ENOG4105MPD	Cytochrome
WP2S18C03_00710	ENOG4105CPQ	Dehydrogenase
WP2S18C03_00720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
WP2S18C03_00730	ENOG41062JF	Transcriptional regulator
WP2S18C03_00740	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
WP2S18C03_00780	ENOG4107TAE	Glycosyl transferase (Group 1
WP2S18C03_00790	ENOG41068D6	Glycosyltransferase
WP2S18C03_00850	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
WP2S18C03_00900	ENOG41061EV	selenium-binding protein YdfZ
WP2S18C03_00910	ENOG4108UK5	Transposase
WP2S18C03_00920	ENOG4108UK5	Transposase
WP2S18C03_00950	ENOG4105C4R	Atp-dependent dna helicase
WP2S18C03_00960	ENOG4105DIH	basic membrane
WP2S18C03_00970	ENOG4108JQ9	ABC transporter
WP2S18C03_00980	ENOG4105UIB	(ABC) transporter
WP2S18C03_01000	ENOG4105CJW	magnesium transporter
WP2S18C03_01010	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
WP2S18C03_01020	ENOG4107V9H	nitrite transporter
WP2S18C03_01030	ENOG4105WZK	nitrite reductase NADPH small subunit
WP2S18C03_01040	ENOG4107QZF	nitrite reductase NADPH large subunit
WP2S18C03_01050	ENOG4107QWP	ABC-2 type transporter
WP2S18C03_01060	ENOG4107QWP	ABC-2 type transporter
WP2S18C03_01070	ENOG4105CJ1	ABC, transporter
WP2S18C03_01080	ENOG4105D0S	secretion protein (HlyD
WP2S18C03_01120	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
WP2S18C03_01130	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
WP2S18C03_01150	ENOG4105C75	arginyL-tRNA synthetase
WP2S18C03_01170	ENOG4105K6V	RNA polymerase
WP2S18C03_01190	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
WP2S18C03_01200	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
WP2S18C03_01210	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
WP2S18C03_01220	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
WP2S18C03_01230	ENOG4105CMR	udp-glucose 4-epimerase
WP2S18C03_01240	ENOG41060NJ	transcriptional regulator
WP2S18C03_01250	ENOG4105CNT	hydrolase family 2
WP2S18C03_01280	ENOG4107SDZ	Galactoside transport system permease protein mglC
WP2S18C03_01290	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_01300	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
WP2S18C03_01330	ENOG4107R28	alpha amylase, catalytic region
WP2S18C03_01360	ENOG4105R8A	Heat shock protein
WP2S18C03_01370	ENOG4105C5I	Dehydrogenase
WP2S18C03_01380	ENOG4108RH0	Crea protein
WP2S18C03_01410	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WP2S18C03_01420	ENOG4105CFQ	glutamine synthetase
WP2S18C03_01430	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
WP2S18C03_01450	ENOG4108HM4	ABC transporter
WP2S18C03_01460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_01470	ENOG4105F38	ABC transporter, permease
WP2S18C03_01480	ENOG4105D38	putrescine abc transporter
WP2S18C03_01490	ENOG4108RPX	mosc domain containing protein
WP2S18C03_01510	ENOG4108VUY	thioesterase Superfamily protein
WP2S18C03_01520	ENOG4105C9U	ATP-dependent DNA helicase RecQ
WP2S18C03_01530	ENOG4105N7H	Cytochrome
WP2S18C03_01540	ENOG4105CNG	UPF0061 protein
WP2S18C03_01560	ENOG4105EX9	Membrane
WP2S18C03_01570	ENOG4105EQR	Transposase IS116 IS110 IS902
WP2S18C03_01590	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
WP2S18C03_01600	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_01610	ENOG4108YH8	Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins (By similarity)
WP2S18C03_01620	ENOG4105VFB	Binds the 23S rRNA (By similarity)
WP2S18C03_01630	ENOG4105C25	Primosomal protein n'
WP2S18C03_01650	ENOG4105CGD	Nad-dependent epimerase dehydratase
WP2S18C03_01660	ENOG4105CIC	tryptophan-specific transport protein
WP2S18C03_01670	ENOG4105C6K	Malic enzyme
WP2S18C03_01680	ENOG4107S2Z	UPF0761 membrane protein
WP2S18C03_01690	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
WP2S18C03_01700	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
WP2S18C03_01720	ENOG4105SUU	thioesterase domain
WP2S18C03_01740	ENOG4105CB5	ATP-dependent DNA helicase recG
WP2S18C03_01750	ENOG4105JIM	Phosphatidylserine synthase
WP2S18C03_01760	ENOG4105C6Z	Gluconate
WP2S18C03_01770	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
WP2S18C03_01780	ENOG4105C01	Dihydroxy-acid dehydratase
WP2S18C03_01790	ENOG4108UHU	Aldolase
WP2S18C03_01820	ENOG4105DIQ	Transcriptional regulator
WP2S18C03_01840	ENOG41063SB	peptidase
WP2S18C03_01850	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
WP2S18C03_01860	ENOG4107YZP	Rhodanese domain protein
WP2S18C03_01870	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
WP2S18C03_01880	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
WP2S18C03_01890	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
WP2S18C03_01900	ENOG4105MJ2	Competence protein
WP2S18C03_01910	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
WP2S18C03_01950	ENOG4105BZM	domain protein
WP2S18C03_01960	ENOG4108RRZ	Transcription elongation factor GreB
WP2S18C03_02000	ENOG4108RRZ	Transcription elongation factor GreB
WP2S18C03_02030	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
WP2S18C03_02040	ENOG4105F5W	AtP-binding protein
WP2S18C03_02050	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_02140	ENOG4105E0F	Histidine kinase
WP2S18C03_02160	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
WP2S18C03_02170	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
WP2S18C03_02180	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
WP2S18C03_02190	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
WP2S18C03_02200	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WP2S18C03_02210	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
WP2S18C03_02220	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
WP2S18C03_02230	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
WP2S18C03_02240	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
WP2S18C03_02250	ENOG41083MP	50s ribosomal protein l29
WP2S18C03_02260	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
WP2S18C03_02270	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
WP2S18C03_02280	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
WP2S18C03_02290	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WP2S18C03_02300	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
WP2S18C03_02310	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
WP2S18C03_02320	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
WP2S18C03_02330	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
WP2S18C03_02340	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
WP2S18C03_02350	ENOG4105VPB	50S ribosomal protein L30
WP2S18C03_02360	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
WP2S18C03_02370	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
WP2S18C03_02380	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WP2S18C03_02390	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
WP2S18C03_02400	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
WP2S18C03_02410	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WP2S18C03_02420	ENOG4108ZT0	50S ribosomal protein l17
WP2S18C03_02440	ENOG4105D05	Receptor
WP2S18C03_02450	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_02460	ENOG4105F5W	AtP-binding protein
WP2S18C03_02470	ENOG4105D05	Receptor
WP2S18C03_02480	ENOG4105BZU	Histidine kinase
WP2S18C03_02490	ENOG4105E0F	Histidine kinase
WP2S18C03_02530	ENOG4105CWB	LysR family transcriptional Regulator
WP2S18C03_02550	ENOG4105C2I	pirin domain protein
WP2S18C03_02560	ENOG4108VBZ	doxx family
WP2S18C03_02570	ENOG4105DSY	exodeoxyribonuclease V, gamma
WP2S18C03_02580	ENOG4107QKA	exodeoxyribonuclease V beta
WP2S18C03_02590	ENOG4107QYX	exodeoxyribonuclease v alpha
WP2S18C03_02630	ENOG4105BZU	Histidine kinase
WP2S18C03_02650	ENOG4105CEE	C4-dicarboxylate transporter
WP2S18C03_02700	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
WP2S18C03_02720	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_02780	ENOG4108IQK	o-acetylhomoserine
WP2S18C03_02840	ENOG4107IFA	Lipase (EC 3.1.1.3)
WP2S18C03_02850	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
WP2S18C03_02860	ENOG4108UDW	Transcriptional regulator, luxr family
WP2S18C03_02900	ENOG4105RHY	Pfam:UPF0157
WP2S18C03_02910	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
WP2S18C03_02960	ENOG4105MYG	DNA polymerase iii, chi subunit
WP2S18C03_02970	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
WP2S18C03_02980	ENOG4108M8S	permease YjgP YjgQ family protein
WP2S18C03_02990	ENOG4108K5H	permease YjgP YjgQ family protein
WP2S18C03_03000	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_03010	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_03280	ENOG4105ED4	portal protein
WP2S18C03_03500	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WP2S18C03_03510	ENOG4105DFP	Integrase
WP2S18C03_03630	ENOG4108IRC	dna polymerase iii
WP2S18C03_03650	ENOG4105E0K	tonB-dependent siderophore receptor
WP2S18C03_03670	ENOG4105F5W	AtP-binding protein
WP2S18C03_03680	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_03710	ENOG4105C5B	carbamate kinase
WP2S18C03_03720	ENOG4105DBV	ornithine carbamoyltransferase
WP2S18C03_03730	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
WP2S18C03_03740	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_03750	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_03760	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP2S18C03_03770	ENOG4105C34	Pseudouridine synthase
WP2S18C03_03780	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
WP2S18C03_03790	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
WP2S18C03_03800	ENOG4107T8T	UPF0173 metal-dependent hydrolase
WP2S18C03_03810	ENOG4105CU9	asparagine synthetase A
WP2S18C03_03820	ENOG4108VVK	transcriptional Regulator, AsnC
WP2S18C03_03850	ENOG410642E	Short chain dehydrogenase
WP2S18C03_03880	ENOG4107WP9	Histidine kinase
WP2S18C03_03900	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WP2S18C03_03910	ENOG4108UQ5	membrane protein YcdZ
WP2S18C03_03940	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
WP2S18C03_03970	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
WP2S18C03_03980	ENOG4105IFJ	Histidine kinase
WP2S18C03_04000	ENOG4107QY8	reductase
WP2S18C03_04010	ENOG4105CUW	cytochrome C-TYPE protein
WP2S18C03_04020	ENOG4105BZU	Histidine kinase
WP2S18C03_04040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
WP2S18C03_04060	ENOG4107ZYR	domain protein
WP2S18C03_04070	ENOG4105D4A	Cell wall formation (By similarity)
WP2S18C03_04080	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
WP2S18C03_04090	ENOG4105CS9	pantothenic acid kinase
WP2S18C03_04100	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
WP2S18C03_04110	ENOG4105PM1	preprotein translocase subunit SecE
WP2S18C03_04120	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
WP2S18C03_04130	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
WP2S18C03_04140	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
WP2S18C03_04150	ENOG4108VZM	50s ribosomal protein L10
WP2S18C03_04160	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
WP2S18C03_04170	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WP2S18C03_04180	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
WP2S18C03_04190	ENOG4105WWK	YheO domain protein
WP2S18C03_04200	ENOG4105KME	endoribonuclease L-psp
WP2S18C03_04210	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
WP2S18C03_04220	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
WP2S18C03_04230	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
WP2S18C03_04240	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
WP2S18C03_04250	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
WP2S18C03_04260	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
WP2S18C03_04270	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
WP2S18C03_04280	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
WP2S18C03_04300	ENOG4105EJ2	Transcriptional regulator
WP2S18C03_04330	ENOG4107FS9	Membrane
WP2S18C03_04360	ENOG4105JQN	Transcriptional regulator
WP2S18C03_04390	ENOG4105VVZ	metal-binding protein
WP2S18C03_04400	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
WP2S18C03_04440	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
WP2S18C03_04460	ENOG4107RZC	phospholipase d
WP2S18C03_04490	ENOG4105CUG	Oligopeptidase b
WP2S18C03_04520	ENOG4105EMU	Dehydrogenase
WP2S18C03_04530	ENOG4108W5M	transcriptional regulator
WP2S18C03_04540	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
WP2S18C03_04590	ENOG4106H78	methyltransferase
WP2S18C03_04600	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
WP2S18C03_04610	ENOG4105CAK	Cell division ATP-binding protein ftsE
WP2S18C03_04620	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
WP2S18C03_04630	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WP2S18C03_04640	ENOG41077A9	carbonic anhydrase
WP2S18C03_04650	ENOG4105CZE	histidine utilization repressor
WP2S18C03_04660	ENOG4105CI2	imidazolone-5-propionate hydrolase
WP2S18C03_04670	ENOG41088SP	formiminoglutamate hydrolase
WP2S18C03_04680	ENOG4105CGP	Urocanate hydratase
WP2S18C03_04690	ENOG4105C84	Histidine ammonia-lyase
WP2S18C03_04700	ENOG4105EWV	Sodium calcium exchanger membrane region
WP2S18C03_04720	ENOG4107XTP	(EAL) domain protein
WP2S18C03_04730	ENOG41062P1	Diguanylate cyclase phosphodiesterase
WP2S18C03_04820	ENOG4107QHF	type ii secretion system protein e
WP2S18C03_04830	ENOG4105D7Q	type ii secretion system
WP2S18C03_04870	ENOG4106855	Competence protein
WP2S18C03_04950	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
WP2S18C03_04960	ENOG4105VQ7	Rod shape-determining protein MreD
WP2S18C03_04970	ENOG4108Z03	MAF-like protein
WP2S18C03_04980	ENOG4105C03	ribonuclease
WP2S18C03_04990	ENOG4105QD6	exported protein
WP2S18C03_05020	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
WP2S18C03_05030	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
WP2S18C03_05040	ENOG4106173	Uncharacterized protein conserved in bacteria (DUF2057)
WP2S18C03_05050	ENOG4105FCK	Membrane
WP2S18C03_05060	ENOG4105C5Y	PTS System
WP2S18C03_05070	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
WP2S18C03_05110	ENOG4105CSH	Transporter
WP2S18C03_05180	ENOG4105EEQ	Na H antiporter
WP2S18C03_05190	ENOG4105C3R	Methionine synthase
WP2S18C03_05200	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
WP2S18C03_05220	ENOG4105ETX	regulatoR
WP2S18C03_05270	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
WP2S18C03_05280	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
WP2S18C03_05290	ENOG4105D06	uba thif-type nad fad binding protein
WP2S18C03_05310	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
WP2S18C03_05320	ENOG4105D41	biosynthesis protein thiH
WP2S18C03_05360	ENOG4105EQK	-acetyltransferase
WP2S18C03_05380	ENOG4105BZU	Histidine kinase
WP2S18C03_05390	ENOG4105C44	Serine transporter
WP2S18C03_05400	ENOG4108TPP	exopolysaccharide synthesis
WP2S18C03_05430	ENOG4105BZU	Histidine kinase
WP2S18C03_05440	ENOG4105BZU	Histidine kinase
WP2S18C03_05450	ENOG4108XTF	Outer Membrane Lipoprotein
WP2S18C03_05460	ENOG4108R6G	acetyltransferase
WP2S18C03_05480	ENOG4105VXR	cytoplasmic protein
WP2S18C03_05510	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
WP2S18C03_05520	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
WP2S18C03_05530	ENOG4105VEJ	Heat shock protein
WP2S18C03_05560	ENOG4105IPI	Membrane
WP2S18C03_05600	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
WP2S18C03_05620	ENOG4105VDH	Dihydroxyacetone kinase
WP2S18C03_05630	ENOG4108UTZ	Dihydroxyacetone kinase
WP2S18C03_05640	ENOG4105CMT	Dihydroxyacetone kinase
WP2S18C03_05660	ENOG4105C7N	Xanthine uracil vitamin C permease
WP2S18C03_05740	ENOG4108ZQS	transposase
WP2S18C03_05800	ENOG4105C7H	Helicase, RecD TraA family
WP2S18C03_05870	ENOG4108UUM	single-stranded DNA-binding protein
WP2S18C03_05880	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
WP2S18C03_05890	ENOG4105BZU	Histidine kinase
WP2S18C03_05910	ENOG4105EIF	outer membrane protein W
WP2S18C03_05920	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_05950	ENOG4105SYT	Methylenetetrahydrofolate reductase
WP2S18C03_05970	ENOG4105DKK	Benzoate
WP2S18C03_05980	ENOG4108JCI	Transcriptional regulator
WP2S18C03_06010	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_06020	ENOG4105F5W	AtP-binding protein
WP2S18C03_06030	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_06040	ENOG4105F5W	AtP-binding protein
WP2S18C03_06070	ENOG4105CD5	CoA-binding domain protein
WP2S18C03_06120	ENOG4105DIJ	Phosphoethanolamine transferase
WP2S18C03_06130	ENOG4105DIJ	Phosphoethanolamine transferase
WP2S18C03_06170	ENOG4105VUF	Transcriptional regulator
WP2S18C03_06200	ENOG4107SJW	iron permease, FTR1
WP2S18C03_06210	ENOG4108C33	Resolvase
WP2S18C03_06260	ENOG4105BZU	Histidine kinase
WP2S18C03_06320	ENOG4108VSE	mercuric transport protein
WP2S18C03_06330	ENOG4105W1Y	Transcriptional regulator
WP2S18C03_06340	ENOG41061MD	high-affinity nickel-transporter
WP2S18C03_06410	ENOG4105KT5	UmuD protein
WP2S18C03_06420	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
WP2S18C03_06490	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
WP2S18C03_06500	ENOG4105CMQ	Chloride channel
WP2S18C03_06520	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
WP2S18C03_06540	ENOG4105DFD	Na H antiporter
WP2S18C03_06570	ENOG4105F5W	AtP-binding protein
WP2S18C03_06580	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_06600	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
WP2S18C03_06610	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
WP2S18C03_06620	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
WP2S18C03_06630	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
WP2S18C03_06640	ENOG4105I7R	Adenylate cyclase
WP2S18C03_06650	ENOG4107IX6	phosphate transport regulator
WP2S18C03_06660	ENOG4105CJ3	phosphate transporter
WP2S18C03_06670	ENOG4105CFH	Aspartokinase
WP2S18C03_06680	ENOG4105C28	cystathionine
WP2S18C03_06690	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
WP2S18C03_06710	ENOG4108Z7R	Chaperone CsaA
WP2S18C03_06720	ENOG4105C44	Serine transporter
WP2S18C03_06730	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
WP2S18C03_06740	ENOG4107RK2	ADP-ribose diphosphatase NudE
WP2S18C03_06750	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
WP2S18C03_06780	ENOG4108UW5	maltose o-acetyltransferase
WP2S18C03_06790	ENOG4107PU6	Membrane
WP2S18C03_06800	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
WP2S18C03_06820	ENOG4108I5D	sulfate abc transporter
WP2S18C03_06830	ENOG4105ECW	sulfate abc transporter
WP2S18C03_06840	ENOG4108IJ6	ABC transporter
WP2S18C03_06850	ENOG4107R11	Transcriptional regulator
WP2S18C03_06860	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
WP2S18C03_06870	ENOG4105DRP	amino acid AbC transporter
WP2S18C03_06900	ENOG4105CDA	abc transporter atp-binding protein
WP2S18C03_06910	ENOG4105CT1	(ABC) transporter
WP2S18C03_06920	ENOG4108M1A	Chitin-binding protein
WP2S18C03_06930	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_06960	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
WP2S18C03_06990	ENOG4105G0K	glycine radical enzyme YjjI family
WP2S18C03_07000	ENOG41076CZ	activating enzyme
WP2S18C03_07030	ENOG4105CGF	Aromatic amino acid aminotransferase
WP2S18C03_07120	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
WP2S18C03_07130	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_07150	ENOG4108QYW	Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine (By similarity)
WP2S18C03_07190	ENOG4105XTV	UPF0231 protein
WP2S18C03_07200	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
WP2S18C03_07210	ENOG4107QQ0	gntp family
WP2S18C03_07220	ENOG4105BZW	Glycerate kinase
WP2S18C03_07250	ENOG4105HEI	LysR family (Transcriptional regulator
WP2S18C03_07260	ENOG4105D9N	nucleoside
WP2S18C03_07280	ENOG4105VZ9	UPF0235 protein
WP2S18C03_07290	ENOG4108VIA	integral membrane protein
WP2S18C03_07300	ENOG4105II7	pyrroline-5-carboxylate reductase
WP2S18C03_07310	ENOG4105DFA	alanine racemase domain protein
WP2S18C03_07320	ENOG4105CZX	twitching motility protein
WP2S18C03_07360	ENOG4105CZX	twitching motility protein
WP2S18C03_07370	ENOG4105D1Q	UPF0246 protein
WP2S18C03_07400	ENOG4108YZN	class I peptide chain release factor
WP2S18C03_07410	ENOG4108YZA	Nitrogen regulatory protein pii
WP2S18C03_07440	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_07450	ENOG4105EZR	dyp-type peroxidase family protein
WP2S18C03_07460	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
WP2S18C03_07470	ENOG4105E5Z	arginine transporter ATP-binding subunit
WP2S18C03_07480	ENOG4106PMH	Extracellular solute-binding protein family 3
WP2S18C03_07490	ENOG4105GBT	ABC transporter
WP2S18C03_07500	ENOG4105DMR	ABC, transporter
WP2S18C03_07510	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
WP2S18C03_07520	ENOG4108UV7	flagellar protein motX
WP2S18C03_07530	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
WP2S18C03_07550	ENOG4108JU6	CBS domain protein
WP2S18C03_07560	ENOG4106KVJ	cytochrome C assembly protein
WP2S18C03_07570	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WP2S18C03_07580	ENOG4105K5M	30s ribosomal protein S16
WP2S18C03_07590	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
WP2S18C03_07600	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
WP2S18C03_07610	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
WP2S18C03_07640	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
WP2S18C03_07650	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
WP2S18C03_07660	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
WP2S18C03_07670	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
WP2S18C03_07680	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
WP2S18C03_07700	ENOG41063Z6	transcriptional regulator, lysR family
WP2S18C03_07710	ENOG41080HT	Transcriptional regulator, arsr family
WP2S18C03_07720	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
WP2S18C03_07730	ENOG4105CJR	Integral membrane protein (MviN
WP2S18C03_07740	ENOG4105DTN	riboflavin biosynthesis protein ribF
WP2S18C03_07750	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
WP2S18C03_07760	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
WP2S18C03_07770	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
WP2S18C03_07780	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
WP2S18C03_07850	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_07860	ENOG4105F5W	AtP-binding protein
WP2S18C03_07940	ENOG4108ZUW	Major pilin subunit
WP2S18C03_07950	ENOG4105C4K	Nad synthetase
WP2S18C03_07960	ENOG4108YZA	Nitrogen regulatory protein pii
WP2S18C03_07980	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
WP2S18C03_07990	ENOG4106855	Competence protein
WP2S18C03_08000	ENOG4105EYA	deoxyribonuclease
WP2S18C03_08010	ENOG4105D9N	nucleoside
WP2S18C03_08030	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
WP2S18C03_08040	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
WP2S18C03_08050	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
WP2S18C03_08060	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
WP2S18C03_08080	ENOG4105EAC	phosphoserine phosphatase
WP2S18C03_08110	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
WP2S18C03_08130	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
WP2S18C03_08140	ENOG4105K70	DNA-binding protein
WP2S18C03_08170	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
WP2S18C03_08180	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
WP2S18C03_08190	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
WP2S18C03_08200	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
WP2S18C03_08210	ENOG4105DP0	ferredoxin-NADP reductase
WP2S18C03_08270	ENOG4105W39	Membrane
WP2S18C03_08290	ENOG4105D9M	gamma-glutamylcysteine synthetase
WP2S18C03_08300	ENOG4108IQE	Amp-dependent synthetase and ligase
WP2S18C03_08310	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
WP2S18C03_08340	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
WP2S18C03_08360	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
WP2S18C03_08380	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
WP2S18C03_08390	ENOG4108MJ3	acetyltransferase
WP2S18C03_08400	ENOG4105EV4	Multidrug resistance protein mdtH
WP2S18C03_08430	ENOG4108Z9I	-acetyltransferase
WP2S18C03_08440	ENOG4105D9U	N-acetyltransferase
WP2S18C03_08460	ENOG4105D9R	oxidoreductase
WP2S18C03_08480	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
WP2S18C03_08490	ENOG4105CSA	Coproporphyrinogen iii oxidase
WP2S18C03_08500	ENOG4105VCN	Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system
WP2S18C03_08520	ENOG4105DC1	bifunctional purine biosynthesis protein purh
WP2S18C03_08530	ENOG4105C12	Phosphoribosylglycinamide synthetase
WP2S18C03_08560	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WP2S18C03_08570	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
WP2S18C03_08580	ENOG4105KTH	gatB Yqey
WP2S18C03_08590	ENOG4105VCC	30S ribosomal protein S21
WP2S18C03_08600	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
WP2S18C03_08610	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
WP2S18C03_08620	ENOG4108IJ0	Aspartate ammonia-lyase
WP2S18C03_08630	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
WP2S18C03_08650	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
WP2S18C03_08660	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
WP2S18C03_08680	ENOG4105BZU	Histidine kinase
WP2S18C03_08710	ENOG4105F5W	AtP-binding protein
WP2S18C03_08720	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_08750	ENOG4108IAB	Phoh family
WP2S18C03_08760	ENOG4107T0D	ABC, transporter
WP2S18C03_08770	ENOG4106SMU	thiamine transporter membrane protein
WP2S18C03_08810	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
WP2S18C03_08820	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
WP2S18C03_08840	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
WP2S18C03_08890	ENOG4105C7K	acetolactate synthase
WP2S18C03_08900	ENOG4108ZP8	Acetolactate synthase small subunit
WP2S18C03_08910	ENOG4108NIW	Leucine export protein LeuE
WP2S18C03_08920	ENOG4107R11	Transcriptional regulator
WP2S18C03_08990	ENOG4108YX2	DNA-binding protein
WP2S18C03_09000	ENOG410679B	prophage CP4-57 regulatory protein alpA
WP2S18C03_09090	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_09100	ENOG4105F5W	AtP-binding protein
WP2S18C03_09120	ENOG4108YGG	dna repair protein
WP2S18C03_09210	ENOG4105MAW	Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles
WP2S18C03_09220	ENOG4105CVR	type I restriction-modification system
WP2S18C03_09230	ENOG4105EKX	Restriction modification system DNA (Specificity
WP2S18C03_09240	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
WP2S18C03_09240	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
WP2S18C03_09260	ENOG4105DZR	Type I site-specific deoxyribonuclease
WP2S18C03_09270	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_09280	ENOG4105F5W	AtP-binding protein
WP2S18C03_09320	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
WP2S18C03_09360	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
WP2S18C03_09370	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
WP2S18C03_09390	ENOG4107V40	secretion protein, HlyD family
WP2S18C03_09450	ENOG4105I93	response regulator
WP2S18C03_09460	ENOG4105DUX	Transporter
WP2S18C03_09470	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
WP2S18C03_09480	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
WP2S18C03_09490	ENOG4105C6K	Malic enzyme
WP2S18C03_09500	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
WP2S18C03_09520	ENOG4105XWI	UPF0304 protein
WP2S18C03_09530	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP2S18C03_09540	ENOG4105RH4	Glycine cleavage system transcriptional repressor
WP2S18C03_09550	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
WP2S18C03_09560	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
WP2S18C03_09570	ENOG4107QWK	SAICAR synthetase
WP2S18C03_09590	ENOG4105EXG	Transcriptional regulator
WP2S18C03_09600	ENOG4108Q67	UPF0319 protein
WP2S18C03_09640	ENOG4105BZU	Histidine kinase
WP2S18C03_09650	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
WP2S18C03_09670	ENOG4105BZU	Histidine kinase
WP2S18C03_09680	ENOG4105BZU	Histidine kinase
WP2S18C03_09690	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_09700	ENOG4105MDZ	Transcriptional activator rfaH
WP2S18C03_09710	ENOG4105D01	(LipO)protein
WP2S18C03_09720	ENOG4108UMI	ABC transporter, permease
WP2S18C03_09730	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_09760	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
WP2S18C03_09770	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
WP2S18C03_09780	ENOG4105K8N	protein family UPF0079, ATPase
WP2S18C03_09790	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
WP2S18C03_09800	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
WP2S18C03_09810	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
WP2S18C03_09820	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
WP2S18C03_09830	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
WP2S18C03_09840	ENOG4107QJR	hflk protein
WP2S18C03_09850	ENOG4105EPW	hflc protein
WP2S18C03_09870	ENOG4105EAH	synthase
WP2S18C03_09880	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
WP2S18C03_09890	ENOG4105K46	50S ribosomal protein l27
WP2S18C03_09900	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WP2S18C03_09910	ENOG4105DWD	nucleoside recognition domain protein
WP2S18C03_09920	ENOG4105DEN	Luciferase family
WP2S18C03_09940	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
WP2S18C03_09960	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
WP2S18C03_09970	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
WP2S18C03_09980	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
WP2S18C03_09990	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
WP2S18C03_10000	ENOG4105EHM	Aminoglycoside phosphotransferase
WP2S18C03_10010	ENOG4108S0S	Nucleotidyl transferase
WP2S18C03_10020	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
WP2S18C03_10030	ENOG4105CIN	aminoacyl-histidine dipeptidase
WP2S18C03_10050	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
WP2S18C03_10060	ENOG4105V1F	Fermentation respiration switch protein
WP2S18C03_10080	ENOG4108ZQS	transposase
WP2S18C03_10110	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
WP2S18C03_10140	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
WP2S18C03_10150	ENOG4105DJ4	phosphatidylserine decarboxylase
WP2S18C03_10160	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
WP2S18C03_10170	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
WP2S18C03_10180	ENOG4105VEQ	Cold shock protein
WP2S18C03_10200	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_10210	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
WP2S18C03_10220	ENOG4105C7N	Xanthine uracil vitamin C permease
WP2S18C03_10240	ENOG4105C5H	ABC transporter
WP2S18C03_10270	ENOG4105E4C	Lytic transglycosylase catalytic
WP2S18C03_10290	ENOG4105G4C	Periplasmic ligand-binding sensor protein
WP2S18C03_10310	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
WP2S18C03_10330	ENOG4108JQ7	(ABC) transporter
WP2S18C03_10350	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
WP2S18C03_10360	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
WP2S18C03_10370	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
WP2S18C03_10380	ENOG4105D07	Signal peptide peptidase, SppA
WP2S18C03_10390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
WP2S18C03_10400	ENOG41069NU	Nitroreductase
WP2S18C03_10420	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
WP2S18C03_10430	ENOG4105CIS	alcohol dehydrogenase
WP2S18C03_10440	ENOG4105HEI	LysR family (Transcriptional regulator
WP2S18C03_10450	ENOG4105CI1	PTS System
WP2S18C03_10460	ENOG4108IA2	Sodium pantothenate symporter
WP2S18C03_10470	ENOG4105RG0	Membrane
WP2S18C03_10480	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
WP2S18C03_10490	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
WP2S18C03_10500	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
WP2S18C03_10510	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
WP2S18C03_10530	ENOG4105BZU	Histidine kinase
WP2S18C03_10550	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
WP2S18C03_10580	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
WP2S18C03_10600	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
WP2S18C03_10610	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
WP2S18C03_10640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
WP2S18C03_10650	ENOG4107YIM	Involved in the transcription termination process (By similarity)
WP2S18C03_10660	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
WP2S18C03_10670	ENOG4108ZAI	phosphatidylglycerophosphatase a
WP2S18C03_10690	ENOG4108JQ6	ABC transporter
WP2S18C03_10700	ENOG4105DIB	Oligopeptide-binding protein
WP2S18C03_10710	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_10730	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
WP2S18C03_10740	ENOG4105CTB	Polyprenyl synthetase
WP2S18C03_10750	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
WP2S18C03_10760	ENOG4105E14	MotA TolQ exbB proton channel
WP2S18C03_10770	ENOG4107XSU	flagellar motor protein motb
WP2S18C03_10770	ENOG4107XSU	flagellar motor protein motb
WP2S18C03_10780	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
WP2S18C03_10800	ENOG4105HBR	Rna-binding protein
WP2S18C03_10810	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
WP2S18C03_10820	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
WP2S18C03_10830	ENOG4105EEI	dihydropteroate synthase
WP2S18C03_10840	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
WP2S18C03_10850	ENOG4105CP7	Triose-phosphate isomerase
WP2S18C03_10860	ENOG4105NTZ	Preprotein translocase subunit SecG
WP2S18C03_10870	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
WP2S18C03_10880	ENOG4105CHV	Transcription elongation factor NusA
WP2S18C03_10890	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
WP2S18C03_10900	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
WP2S18C03_10910	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
WP2S18C03_10920	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
WP2S18C03_10930	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
WP2S18C03_10940	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
WP2S18C03_10950	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
WP2S18C03_10960	ENOG4105BZU	Histidine kinase
WP2S18C03_10970	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_11000	ENOG4105YFD	chemotaxis, protein
WP2S18C03_11010	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_11030	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_11040	ENOG4105F5W	AtP-binding protein
WP2S18C03_11050	ENOG4105DQ6	Transposase
WP2S18C03_11080	ENOG4108ZQS	transposase
WP2S18C03_11090	ENOG4105CBS	Chea signal transduction histidine kinase
WP2S18C03_11120	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_11130	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
WP2S18C03_11150	ENOG4105N14	lysine exporter protein LysE YggA
WP2S18C03_11160	ENOG4105CFP	Peptidase U32
WP2S18C03_11170	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
WP2S18C03_11180	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
WP2S18C03_11210	ENOG4105CTD	carboxy-peptidase
WP2S18C03_11260	ENOG4105E1F	short-chain dehydrogenase reductase
WP2S18C03_11270	ENOG4105J5J	Outer membrane porin
WP2S18C03_11280	ENOG4108W2P	Methyl-accepting chemotaxis
WP2S18C03_11330	ENOG4105CQC	Prephenate dehydratase
WP2S18C03_11360	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
WP2S18C03_11390	ENOG4107SEY	Conserved Protein
WP2S18C03_11400	ENOG4108XDN	Transcriptional regulator
WP2S18C03_11410	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
WP2S18C03_11430	ENOG4107FW0	short-chain dehydrogenase reductase
WP2S18C03_11460	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
WP2S18C03_11520	ENOG4105CJ2	(LipO)protein
WP2S18C03_11530	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
WP2S18C03_11540	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
WP2S18C03_11550	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
WP2S18C03_11560	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
WP2S18C03_11570	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
WP2S18C03_11580	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
WP2S18C03_11590	ENOG4105M85	Bola protein
WP2S18C03_11600	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
WP2S18C03_11620	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WP2S18C03_11640	ENOG4105DRB	nucleoside-specific channel-forming protein
WP2S18C03_11650	ENOG4108VPT	UPF0234 protein
WP2S18C03_11660	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
WP2S18C03_11670	ENOG4107S0N	DJ-1 family
WP2S18C03_11690	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
WP2S18C03_11700	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_11710	ENOG4105ETT	transcriptional Regulator, LysR family
WP2S18C03_11730	ENOG4105M08	Membrane
WP2S18C03_11740	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
WP2S18C03_11760	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
WP2S18C03_11770	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
WP2S18C03_11780	ENOG4105EWT	decarboxylase family
WP2S18C03_11790	ENOG4105BZU	Histidine kinase
WP2S18C03_11810	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
WP2S18C03_11820	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
WP2S18C03_11830	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
WP2S18C03_11890	ENOG4105WP7	tRNA pseudouridine synthase C
WP2S18C03_11900	ENOG4105DR9	pseudouridine synthase
WP2S18C03_11910	ENOG4105QDK	Flavodoxin
WP2S18C03_11930	ENOG4107W52	maltose operon periplasmic protein
WP2S18C03_11940	ENOG4105CI1	PTS System
WP2S18C03_11950	ENOG4108T8E	UPF0325 protein
WP2S18C03_11960	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
WP2S18C03_11970	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
WP2S18C03_11980	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
WP2S18C03_11990	ENOG4105CE9	30S ribosomal protein S2
WP2S18C03_12000	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
WP2S18C03_12010	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
WP2S18C03_12020	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
WP2S18C03_12040	ENOG4105KNE	Phosphatidate cytidylyltransferase
WP2S18C03_12050	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
WP2S18C03_12060	ENOG4105DZP	Membrane-associated zinc metalloprotease
WP2S18C03_12070	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP2S18C03_12080	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
WP2S18C03_12090	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
WP2S18C03_12100	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
WP2S18C03_12110	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
WP2S18C03_12120	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
WP2S18C03_12130	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
WP2S18C03_12140	ENOG4105C0B	DNA polymerase III (alpha subunit)
WP2S18C03_12150	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
WP2S18C03_12170	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
WP2S18C03_12180	ENOG4105BZG	amino acid carrier protein
WP2S18C03_12190	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_12200	ENOG4105F5W	AtP-binding protein
WP2S18C03_12210	ENOG4105F8C	transglutaminase domain-containing protein
WP2S18C03_12230	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
WP2S18C03_12240	ENOG41066YJ	Beta-lactamase
WP2S18C03_12280	ENOG4105DUX	Transporter
WP2S18C03_12290	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
WP2S18C03_12300	ENOG4108UJU	UPF0301 protein
WP2S18C03_12320	ENOG4105D7Z	glutathione synthase
WP2S18C03_12330	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
WP2S18C03_12350	ENOG4105GPY	SprT protein
WP2S18C03_12360	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
WP2S18C03_12370	ENOG4105CV1	Transketolase (EC 2.2.1.1)
WP2S18C03_12390	ENOG4105KME	endoribonuclease L-psp
WP2S18C03_12420	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
WP2S18C03_12430	ENOG4105DR5	peptidase
WP2S18C03_12440	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
WP2S18C03_12470	ENOG4105C7K	acetolactate synthase
WP2S18C03_12500	ENOG4105EQ2	LysR family Transcriptional regulator
WP2S18C03_12510	ENOG4105C44	Serine transporter
WP2S18C03_12540	ENOG4105EXG	Transcriptional regulator
WP2S18C03_12550	ENOG4105DVH	amino acid
WP2S18C03_12560	ENOG4108M3R	transcriptional activator CadC
WP2S18C03_12570	ENOG4105D5Q	Arginine ornithine antiporter
WP2S18C03_12580	ENOG4105CXN	decarboxylase
WP2S18C03_12590	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
WP2S18C03_12610	ENOG4105C9K	Endothelin-converting enzyme 1
WP2S18C03_12620	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
WP2S18C03_12630	ENOG4105BZU	Histidine kinase
WP2S18C03_12700	ENOG4107T9C	Alpha amylase catalytic region
WP2S18C03_12750	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
WP2S18C03_12760	ENOG4105EAQ	(twin-arginine translocation) pathway signal
WP2S18C03_12780	ENOG4105EN6	Membrane
WP2S18C03_12790	ENOG4105EXN	Sulfate transport protein CysZ
WP2S18C03_12800	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
WP2S18C03_12810	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
WP2S18C03_12820	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
WP2S18C03_12840	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
WP2S18C03_12850	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
WP2S18C03_12900	ENOG4105J12	Multidrug resistance protein mdtN
WP2S18C03_12930	ENOG4105D2K	citrate carrier protein
WP2S18C03_12940	ENOG4107R1I	NAD-dependent malic enzyme
WP2S18C03_12950	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
WP2S18C03_12960	ENOG4106YYS	transcriptional regulatory protein
WP2S18C03_12970	ENOG4108IPJ	Membrane
WP2S18C03_12990	ENOG4105BZU	Histidine kinase
WP2S18C03_13000	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
WP2S18C03_13010	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WP2S18C03_13020	ENOG4105BZU	Histidine kinase
WP2S18C03_13030	ENOG4105DJH	phosphate
WP2S18C03_13050	ENOG4105ERG	peptidase m48, ste24p
WP2S18C03_13080	ENOG4106N3A	copper homeostasis protein cutc
WP2S18C03_13090	ENOG4108V1T	peptidylprolyl cis-trans isomerase
WP2S18C03_13120	ENOG4105PTV	Nudix Hydrolase
WP2S18C03_13170	ENOG4105BZG	amino acid carrier protein
WP2S18C03_13180	ENOG4105C2W	permease
WP2S18C03_13190	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
WP2S18C03_13200	ENOG4105RKX	Protein of unknown function (DUF2498)
WP2S18C03_13210	ENOG4105UQX	Mate efflux family protein
WP2S18C03_13220	ENOG4105ECQ	AraC Family Transcriptional Regulator
WP2S18C03_13230	ENOG4107R1I	NAD-dependent malic enzyme
WP2S18C03_13250	ENOG4105UYK	outer membrane protein a
WP2S18C03_13270	ENOG4105UYK	outer membrane protein a
WP2S18C03_13300	ENOG4105C8J	)-transporter
WP2S18C03_13320	ENOG4105D78	K07001 NTE family protein
WP2S18C03_13330	ENOG4105BZU	Histidine kinase
WP2S18C03_13350	ENOG4105BZS	acriflavin resistance protein
WP2S18C03_13360	ENOG4105CCT	upf0313 protein
WP2S18C03_13430	ENOG4105EP9	oxidoreductase
WP2S18C03_13440	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
WP2S18C03_13450	ENOG4105EM2	membrane
WP2S18C03_13460	ENOG4108MN8	Membrane
WP2S18C03_13480	ENOG4105F8D	glycoside hydrolase family 4
WP2S18C03_13490	ENOG4105EZV	Transcriptional regulator
WP2S18C03_13500	ENOG4105VCP	PTS System
WP2S18C03_13510	ENOG4105CS2	ec 3.2.1.21
WP2S18C03_13520	ENOG4105CK1	PTS System
WP2S18C03_13530	ENOG4105VZJ	PTS System
WP2S18C03_13610	ENOG4108VAU	general secretion pathway protein G
WP2S18C03_13620	ENOG4105D7Q	type ii secretion system
WP2S18C03_13630	ENOG4107QHF	type ii secretion system protein e
WP2S18C03_13650	ENOG4108XKW	General secretion pathway protein C
WP2S18C03_13680	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
WP2S18C03_13720	ENOG4105C6T	cysteine synthase
WP2S18C03_13730	ENOG4105KZ7	phosphocarrier protein hpr
WP2S18C03_13740	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
WP2S18C03_13750	ENOG4105C5Y	PTS System
WP2S18C03_13760	ENOG4105BZU	Histidine kinase
WP2S18C03_13770	ENOG4105EGS	Mechanosensitive ion channel
WP2S18C03_13780	ENOG4105CA9	Pyruvate kinase
WP2S18C03_13800	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
WP2S18C03_13810	ENOG4105EYH	Exonuclease
WP2S18C03_13820	ENOG4107RH8	nuclease SbcCD subunit D
WP2S18C03_13840	ENOG4105DH7	May be involved in recombination (By similarity)
WP2S18C03_13850	ENOG4108V1T	peptidylprolyl cis-trans isomerase
WP2S18C03_13880	ENOG4105CUB	amino acid
WP2S18C03_13900	ENOG4105CUB	amino acid
WP2S18C03_13910	ENOG4108JPW	Aminotransferase
WP2S18C03_13920	ENOG4105C26	Dehydrogenase
WP2S18C03_13930	ENOG4107VRI	Transcriptional regulator
WP2S18C03_13940	ENOG4105CJP	fad dependent oxidoreductase
WP2S18C03_14000	ENOG4105KAF	membrAne
WP2S18C03_14030	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
WP2S18C03_14060	ENOG4108R96	Methyltransferase, YaeB family
WP2S18C03_14100	ENOG4108JJ8	(ABC) transporter
WP2S18C03_14110	ENOG4108JJ9	ABC, transporter
WP2S18C03_14120	ENOG41065U4	response regulator
WP2S18C03_14140	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
WP2S18C03_14170	ENOG41085FC	arsR family transcriptional regulator
WP2S18C03_14200	ENOG4105D6J	arsenicaL-resistance protein
WP2S18C03_14230	ENOG4105D9N	nucleoside
WP2S18C03_14240	ENOG4105CAF	HipA N-terminal domain protein
WP2S18C03_14260	ENOG4105S2T	inner membrane protein YbcI
WP2S18C03_14290	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
WP2S18C03_14300	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
WP2S18C03_14310	ENOG4105DK0	Indole-3-glycerol phosphate synthase
WP2S18C03_14320	ENOG4108I0Q	anthranilate phosphoribosyltransferase
WP2S18C03_14330	ENOG4108EFP	Anthranilate synthase component II
WP2S18C03_14340	ENOG4105CRQ	synthase (Component I)
WP2S18C03_14350	ENOG4105DB7	PHP domain protein
WP2S18C03_14360	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
WP2S18C03_14380	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
WP2S18C03_14390	ENOG4105FE9	pseudouridine synthase
WP2S18C03_14400	ENOG4105KJJ	Uncharacterized ACR, COG1993
WP2S18C03_14410	ENOG4107Z6W	Protein CrcB homolog
WP2S18C03_14430	ENOG4105C29	acyl-CoA thioesterase
WP2S18C03_14440	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
WP2S18C03_14450	ENOG4106FVC	RNA methyltransferase
WP2S18C03_14470	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
WP2S18C03_14480	ENOG4105D98	threonine synthase
WP2S18C03_14490	ENOG4105F2I	Transposase
WP2S18C03_14500	ENOG4105F5W	AtP-binding protein
WP2S18C03_14510	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_14520	ENOG4108UK5	Transposase
WP2S18C03_14540	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_14550	ENOG4105F5W	AtP-binding protein
WP2S18C03_14560	ENOG4105D7V	transposase
WP2S18C03_14580	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
WP2S18C03_14590	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
WP2S18C03_14620	ENOG4105VYW	UPF0251 protein
WP2S18C03_14650	ENOG4108IG5	Transcriptional regulator
WP2S18C03_14660	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
WP2S18C03_14670	ENOG4105BZS	acriflavin resistance protein
WP2S18C03_14680	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
WP2S18C03_14690	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
WP2S18C03_14760	ENOG4105CAQ	asparagine synthetase
WP2S18C03_14780	ENOG4107QQG	Dehydrogenase
WP2S18C03_14820	ENOG4105D3Q	Sugar transferase
WP2S18C03_14840	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
WP2S18C03_14850	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
WP2S18C03_14860	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
WP2S18C03_14870	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
WP2S18C03_14880	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
WP2S18C03_14890	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
WP2S18C03_14900	ENOG4108QY5	Ferric enterobactin transport protein
WP2S18C03_14920	ENOG4105F5W	AtP-binding protein
WP2S18C03_14930	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_14940	ENOG4108YX2	DNA-binding protein
WP2S18C03_14970	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
WP2S18C03_14980	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
WP2S18C03_14990	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
WP2S18C03_15000	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
WP2S18C03_15010	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
WP2S18C03_15020	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
WP2S18C03_15030	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WP2S18C03_15040	ENOG4105CFG	Acts as a chaperone (By similarity)
WP2S18C03_15050	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
WP2S18C03_15070	ENOG4105D7K	pfkb domain protein
WP2S18C03_15090	ENOG4108HKT	sucrose-6-phosphate hydrolase
WP2S18C03_15100	ENOG4105WBN	Transcriptional regulator (LacI family
WP2S18C03_15130	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
WP2S18C03_15200	ENOG4105BZU	Histidine kinase
WP2S18C03_15210	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
WP2S18C03_15230	ENOG4105K4T	epimerase
WP2S18C03_15240	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
WP2S18C03_15250	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_15260	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_15270	ENOG4105F5W	AtP-binding protein
WP2S18C03_15280	ENOG4105C0A	alcohol dehydrogenase
WP2S18C03_15290	ENOG4107SXA	Phosphorylase
WP2S18C03_15300	ENOG4105D3G	Pseudouridine synthase
WP2S18C03_15310	ENOG4105DU0	nucleoside hydrolase
WP2S18C03_15340	ENOG4105RX8	Protein of unknown function (DUF1523)
WP2S18C03_15360	ENOG410829K	Lysine exporter protein (Lyse ygga)
WP2S18C03_15390	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
WP2S18C03_15420	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
WP2S18C03_15430	ENOG4105KUZ	arsenate reductase
WP2S18C03_15450	ENOG4105CEE	C4-dicarboxylate transporter
WP2S18C03_15460	ENOG4105CH2	amidohydrolase
WP2S18C03_15480	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
WP2S18C03_15500	ENOG4105C5S	asparaginyl-tRNA synthetase
WP2S18C03_15530	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
WP2S18C03_15540	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
WP2S18C03_15550	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
WP2S18C03_15560	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
WP2S18C03_15570	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
WP2S18C03_15580	ENOG4105D0M	Protease HtpX homolog
WP2S18C03_15590	ENOG4105QVC	MOSC domain-containing protein
WP2S18C03_15590	ENOG4105QVC	MOSC domain-containing protein
WP2S18C03_15620	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
WP2S18C03_15640	ENOG4107SRH	Nad-dependent epimerase dehydratase
WP2S18C03_15650	ENOG4105NAU	thioesterase Superfamily protein
WP2S18C03_15680	ENOG41090BQ	Glutaredoxin
WP2S18C03_15690	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
WP2S18C03_15700	ENOG4105CFI	type iii restriction protein res subunit
WP2S18C03_15710	ENOG4105EFX	secretion protein, HlyD family
WP2S18C03_15720	ENOG4105KK7	inner membrane protein YiaW
WP2S18C03_15740	ENOG4108NEV	two component transcriptional regulator, LytTR family
WP2S18C03_15750	ENOG4108HRK	Histidine kinase
WP2S18C03_15760	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
WP2S18C03_15780	ENOG4105DIJ	Phosphoethanolamine transferase
WP2S18C03_15790	ENOG4105E2R	ROK family
WP2S18C03_15800	ENOG4105CE4	GlcNAc 6-P deacetylase
WP2S18C03_15810	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
WP2S18C03_15820	ENOG4105CI1	PTS System
WP2S18C03_15830	ENOG4105E2D	ec 3.2.1.52
WP2S18C03_15850	ENOG4105E2D	ec 3.2.1.52
WP2S18C03_15860	ENOG4105CX6	glutaminyL-tRNA synthetase
WP2S18C03_15870	ENOG41090R7	Ferric uptake
WP2S18C03_15890	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
WP2S18C03_15900	ENOG4105NNH	LexA regulated protein
WP2S18C03_15920	ENOG4105EV9	Alpha Beta Hydrolase
WP2S18C03_15930	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
WP2S18C03_15940	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
WP2S18C03_15950	ENOG4105CVE	Lytic murein transglycosylase
WP2S18C03_15960	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
WP2S18C03_15970	ENOG4108VGW	abc transporter atp-binding protein
WP2S18C03_15980	ENOG4105CXZ	ABC transporter, permease
WP2S18C03_15990	ENOG4105VNH	ABC transporter solute-binding protein
WP2S18C03_16000	ENOG4107QN2	dihydrolipoyl dehydrogenase
WP2S18C03_16010	ENOG4107ZN8	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
WP2S18C03_16030	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
WP2S18C03_16050	ENOG4105CFU	surface antigen
WP2S18C03_16060	ENOG4105MA0	exported protein
WP2S18C03_16080	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
WP2S18C03_16090	ENOG4105BZU	Histidine kinase
WP2S18C03_16100	ENOG4107SC1	transglycosylase
WP2S18C03_16110	ENOG41060NJ	transcriptional regulator
WP2S18C03_16120	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
WP2S18C03_16130	ENOG4105D05	Receptor
WP2S18C03_16140	ENOG4105E4F	Isochorismate synthase
WP2S18C03_16150	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
WP2S18C03_16160	ENOG4105WQI	isochorismatase
WP2S18C03_16170	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
WP2S18C03_16180	ENOG4105C0W	non-ribosomal peptide synthetase
WP2S18C03_16200	ENOG4107RUY	(E1 component), alpha subunit
WP2S18C03_16210	ENOG4105CPP	Dehydrogenase, E1 component
WP2S18C03_16220	ENOG4107QSN	dihydrolipoamide acetyltransferase
WP2S18C03_16230	ENOG4105VEQ	Cold shock protein
WP2S18C03_16280	ENOG4107QRA	Extracellular solute-binding protein, family 5
WP2S18C03_16290	ENOG4108594	Permease of the drug metabolite transporter
WP2S18C03_16300	ENOG4105N2W	Transcriptional regulator
WP2S18C03_16320	ENOG4105F1A	Pyruvate formate-lyase
WP2S18C03_16330	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
WP2S18C03_16350	ENOG4105CPI	Metal Dependent Phosphohydrolase
WP2S18C03_16360	ENOG4105I08	Pseudouridine synthase
WP2S18C03_16380	ENOG4107QSI	ABC, transporter
WP2S18C03_16390	ENOG4108RE9	Phosphodiesterase
WP2S18C03_16420	ENOG4107ESN	Flagella basal body P-ring formation protein flgA
WP2S18C03_16440	ENOG4105BZU	Histidine kinase
WP2S18C03_16450	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
WP2S18C03_16460	ENOG4108ZC9	flagellar basal-body rod protein flgc
WP2S18C03_16480	ENOG4105BZE	flagellar hook protein, FlgE
WP2S18C03_16490	ENOG4108KPB	Flagellar basal-body rod protein FlgF
WP2S18C03_16500	ENOG4105CGA	flagellar basal-body rod protein FlgG
WP2S18C03_16510	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
WP2S18C03_16520	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
WP2S18C03_16530	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
WP2S18C03_16550	ENOG4105DTJ	flagellar hook-associated protein
WP2S18C03_16560	ENOG4105CJW	magnesium transporter
WP2S18C03_16570	ENOG4105C9X	ppx gppa phosphatase
WP2S18C03_16580	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
WP2S18C03_16590	ENOG4105RH4	Glycine cleavage system transcriptional repressor
WP2S18C03_16620	ENOG4105BZU	Histidine kinase
WP2S18C03_16640	ENOG4107QNR	UPF0135 protein
WP2S18C03_16650	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
WP2S18C03_16660	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
WP2S18C03_16670	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
WP2S18C03_16690	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
WP2S18C03_16700	ENOG4108I9X	Isocitrate lyase
WP2S18C03_16710	ENOG4107QP3	malate synthase g
WP2S18C03_16730	ENOG4108Z6B	deaminase
WP2S18C03_16740	ENOG4105C8U	phosphate abc transporter
WP2S18C03_16750	ENOG4105E2Z	phosphate ABC transporter (Permease
WP2S18C03_16760	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_16780	ENOG4105C37	(CBS) domain
WP2S18C03_16800	ENOG4105C3R	Methionine synthase
WP2S18C03_16810	ENOG4105D5Q	Arginine ornithine antiporter
WP2S18C03_16820	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_16830	ENOG4105F5W	AtP-binding protein
WP2S18C03_16840	ENOG4105D5Q	Arginine ornithine antiporter
WP2S18C03_16870	ENOG4105CDA	abc transporter atp-binding protein
WP2S18C03_16880	ENOG4105E5Q	amino acid AbC transporter
WP2S18C03_16890	ENOG4106PMH	Extracellular solute-binding protein family 3
WP2S18C03_16900	ENOG4105BZU	Histidine kinase
WP2S18C03_16910	ENOG4105CXY	transporter
WP2S18C03_16920	ENOG4105BZU	Histidine kinase
WP2S18C03_16930	ENOG4108KX4	response regulator
WP2S18C03_16940	ENOG4105NXH	GreA GreB family elongation factor
WP2S18C03_16990	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
WP2S18C03_17000	ENOG4108ISG	Major Facilitator
WP2S18C03_17010	ENOG4105DGU	Histone deacetylase
WP2S18C03_17030	ENOG4105DVT	helicase
WP2S18C03_17060	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
WP2S18C03_17070	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
WP2S18C03_17080	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
WP2S18C03_17090	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
WP2S18C03_17160	ENOG4105K59	histidine triad (HIT) protein
WP2S18C03_17170	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_17190	ENOG4105CD3	dihydroorotase
WP2S18C03_17210	ENOG4107QJT	sodium dicarboxylate symporter
WP2S18C03_17230	ENOG4105CKW	Inner membrane protein yedI
WP2S18C03_17240	ENOG4105DPN	Oligoendopeptidase f
WP2S18C03_17250	ENOG4105C2W	permease
WP2S18C03_17260	ENOG4105D0Y	UPF0227 protein
WP2S18C03_17270	ENOG4105CEP	NADH dehydrogenase
WP2S18C03_17290	ENOG4105F1A	Pyruvate formate-lyase
WP2S18C03_17300	ENOG4105BZU	Histidine kinase
WP2S18C03_17310	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
WP2S18C03_17330	ENOG4105DN3	alpha-2-macroglobulin domain protein
WP2S18C03_17340	ENOG4108JQB	penicillin-binding protein 1C
WP2S18C03_17370	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
WP2S18C03_17390	ENOG4105EN6	Membrane
WP2S18C03_17400	ENOG4105I03	Flagellin
WP2S18C03_17410	ENOG4105I03	Flagellin
WP2S18C03_17440	ENOG4105MQ3	flagellar protein FliS
WP2S18C03_17490	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
WP2S18C03_17510	ENOG4105D2T	synthase
WP2S18C03_17530	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
WP2S18C03_17540	ENOG4105F0R	Cytidylyltransferase
WP2S18C03_17560	ENOG4105C5E	polysaccharide biosynthesis protein
WP2S18C03_17570	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
WP2S18C03_17590	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
WP2S18C03_17610	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_17620	ENOG4105ECY	inositol monophosphatase
WP2S18C03_17640	ENOG4105CYM	Glutathione S-transferase
WP2S18C03_17650	ENOG4105E5M	Multidrug resistance protein D
WP2S18C03_17660	ENOG4105EJC	lysr family transcriptional regulator
WP2S18C03_17670	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
WP2S18C03_17680	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
WP2S18C03_17690	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
WP2S18C03_17710	ENOG4105D0A	hydroxylase
WP2S18C03_17720	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
WP2S18C03_17730	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
WP2S18C03_17740	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
WP2S18C03_17750	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP2S18C03_17760	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
WP2S18C03_17770	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
WP2S18C03_17800	ENOG4105C85	amino acid
WP2S18C03_17820	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
WP2S18C03_17830	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
WP2S18C03_17860	ENOG4105D01	(LipO)protein
WP2S18C03_17870	ENOG4105E68	Sulfatase
WP2S18C03_17880	ENOG4105PAN	UPF0352 protein
WP2S18C03_17890	ENOG4106V8H	Nucleoid-associated protein
WP2S18C03_17900	ENOG4107FKK	extracellular solute-binding protein family 1
WP2S18C03_17910	ENOG4105D56	permease protein
WP2S18C03_17930	ENOG4108IJ9	(ABC) transporter
WP2S18C03_17940	ENOG4105CSR	polyphosphate kinase 2
WP2S18C03_17980	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
WP2S18C03_17990	ENOG4105ERG	peptidase m48, ste24p
WP2S18C03_18010	ENOG4105K89	arsenate reductase
WP2S18C03_18030	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
WP2S18C03_18040	ENOG4105DYB	Isoaspartyl dipeptidase
WP2S18C03_18050	ENOG4105DWU	Membrane
WP2S18C03_18060	ENOG4108JEH	abc transporter atp-binding protein
WP2S18C03_18070	ENOG4105E89	ABC transporter
WP2S18C03_18080	ENOG4105DSP	amino acid AbC transporter
WP2S18C03_18090	ENOG4106YG3	ABC transporter
WP2S18C03_18140	ENOG4108W1A	pseudouridine synthase
WP2S18C03_18160	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
WP2S18C03_18170	ENOG4105F1J	Homogentisate 1,2-dioxygenase
WP2S18C03_18190	ENOG4108RXX	maleylacetoacetate isomerase
WP2S18C03_18200	ENOG4105CAQ	asparagine synthetase
WP2S18C03_18220	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
WP2S18C03_18230	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
WP2S18C03_18260	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
WP2S18C03_18270	ENOG4105EE5	Membrane protein terC
WP2S18C03_18290	ENOG4105CQB	FAD linked oxidase domain protein
WP2S18C03_18310	ENOG4105KA0	thioesterase Superfamily protein
WP2S18C03_18340	ENOG4105BZU	Histidine kinase
WP2S18C03_18350	ENOG4105D3Y	Na H antiporter
WP2S18C03_18360	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
WP2S18C03_18370	ENOG4105EYK	Phosphatidylglycerophosphatase B
WP2S18C03_18380	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
WP2S18C03_18390	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
WP2S18C03_18410	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
WP2S18C03_18420	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
WP2S18C03_18430	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
WP2S18C03_18440	ENOG4108S3P	Sporulation domain protein
WP2S18C03_18450	ENOG4105K8R	UPF0145 protein
WP2S18C03_18470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
WP2S18C03_18480	ENOG410810Y	Sulfite reductase
WP2S18C03_18490	ENOG4107SHJ	sulfite reductase subunit b
WP2S18C03_18500	ENOG4105D5B	Sulfite reductase, subunit A
WP2S18C03_18520	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
WP2S18C03_18530	ENOG4107T7U	Sulfatase
WP2S18C03_18550	ENOG4105CFH	Aspartokinase
WP2S18C03_18560	ENOG4107QZM	n-acetylglutamate synthase
WP2S18C03_18570	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
WP2S18C03_18610	ENOG4105F2Z	3-oxoadipate enol-lactonase
WP2S18C03_18630	ENOG4107SDU	Methyl-accepting chemotaxis
WP2S18C03_18650	ENOG4105C2C	drug resistance transporter, Bcr CflA
WP2S18C03_18850	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_18860	ENOG4105F5W	AtP-binding protein
WP2S18C03_18870	ENOG4105K8R	UPF0145 protein
WP2S18C03_19020	ENOG4105BZU	Histidine kinase
WP2S18C03_19080	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_19090	ENOG4105F5W	AtP-binding protein
WP2S18C03_19100	ENOG4105DFP	Integrase
WP2S18C03_19130	ENOG4105CHH	sulfate transporter
WP2S18C03_19150	ENOG4105DIJ	Phosphoethanolamine transferase
WP2S18C03_19160	ENOG41080IJ	Diacylglycerol kinase
WP2S18C03_19180	ENOG4105FF5	Membrane
WP2S18C03_19200	ENOG4105JJR	Histidine kinase
WP2S18C03_19210	ENOG4107EXC	regulatoR
WP2S18C03_19360	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_19370	ENOG4105F5W	AtP-binding protein
WP2S18C03_19440	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
WP2S18C03_19450	ENOG4105VEQ	Cold shock protein
WP2S18C03_19460	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
WP2S18C03_19470	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
WP2S18C03_19480	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
WP2S18C03_19490	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
WP2S18C03_19500	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
WP2S18C03_19510	ENOG4107MBR	17 kDa surface antigen
WP2S18C03_19520	ENOG4106TD9	Diguanylate cyclase
WP2S18C03_19530	ENOG4105C3M	thioredoxin reductase
WP2S18C03_19540	ENOG4105DCF	alanine dehydrogenase
WP2S18C03_19550	ENOG4105EW9	transcriptional regulator AsnC family
WP2S18C03_19560	ENOG4105CNU	cell division protein FtsK
WP2S18C03_19570	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
WP2S18C03_19580	ENOG4105D1H	recombination factor protein RarA
WP2S18C03_19590	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
WP2S18C03_19600	ENOG4105E96	Colicin v production protein
WP2S18C03_19610	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
WP2S18C03_19620	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
WP2S18C03_19630	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
WP2S18C03_19640	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
WP2S18C03_19660	ENOG4107RE1	Inosine-guanosine kinase
WP2S18C03_19690	ENOG4105BZU	Histidine kinase
WP2S18C03_19720	ENOG4105F3T	(LipO)protein
WP2S18C03_19740	ENOG4105QZU	Inner membrane protein YfeZ
WP2S18C03_19760	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
WP2S18C03_19770	ENOG4105BZJ	Electron transfer flavoprotein
WP2S18C03_19780	ENOG4105C10	Electron transfer flavoprotein
WP2S18C03_19800	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
WP2S18C03_19810	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
WP2S18C03_19820	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_19830	ENOG4105D4P	Coproporphyrinogen iii oxidase
WP2S18C03_19840	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_19850	ENOG4108V06	Glutathione peroxidase
WP2S18C03_19870	ENOG4105CPF	Cell wall formation (By similarity)
WP2S18C03_19880	ENOG4105C8I	hydrolase, family 38
WP2S18C03_19890	ENOG4105DM4	PTS System
WP2S18C03_19900	ENOG4105FDP	GntR family transcriptional regulator
WP2S18C03_19910	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
WP2S18C03_19960	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
WP2S18C03_19970	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
WP2S18C03_20030	ENOG4105FQ6	thiopurine methyltransferase
WP2S18C03_20040	ENOG4107VK2	coenzyme PQQ biosynthesis protein PqqF
WP2S18C03_20050	ENOG4108BY2	phosphohistidine phosphatase
WP2S18C03_20070	ENOG4108IPJ	Membrane
WP2S18C03_20080	ENOG4108J59	Extracellular solute-binding protein, family 5
WP2S18C03_20090	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WP2S18C03_20100	ENOG4108JA2	transcriptioN-repair coupling factor
WP2S18C03_20120	ENOG4105D60	lipoprotein releasing system transmembrane protein
WP2S18C03_20130	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
WP2S18C03_20140	ENOG4105D60	lipoprotein releasing system transmembrane protein
WP2S18C03_20170	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
WP2S18C03_20180	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
WP2S18C03_20190	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
WP2S18C03_20200	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
WP2S18C03_20220	ENOG4105EIN	peptidylprolyl cis-trans isomerase
WP2S18C03_20230	ENOG4105C5H	ABC transporter
WP2S18C03_20240	ENOG4107QN1	sodium solute
WP2S18C03_20250	ENOG41062QD	Membrane
WP2S18C03_20280	ENOG41060WC	Enoyl-CoA hydratase
WP2S18C03_20290	ENOG4105BZG	amino acid carrier protein
WP2S18C03_20300	ENOG410870W	N-acetyltransferase
WP2S18C03_20310	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
WP2S18C03_20320	ENOG4106HK8	GPR1 FUN34 yaaH family protein
WP2S18C03_20360	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
WP2S18C03_20390	ENOG4105E39	Enoyl-CoA hydratase
WP2S18C03_20400	ENOG4107QX3	carboxylase
WP2S18C03_20410	ENOG4105C1G	acyl-Coa dehydrogenase
WP2S18C03_20420	ENOG4105C1G	acyl-Coa dehydrogenase
WP2S18C03_20430	ENOG4105E39	Enoyl-CoA hydratase
WP2S18C03_20440	ENOG4105E39	Enoyl-CoA hydratase
WP2S18C03_20450	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
WP2S18C03_20470	ENOG4105D5Q	Arginine ornithine antiporter
WP2S18C03_20480	ENOG4105HF0	Membrane
WP2S18C03_20490	ENOG4105VTR	Integrase
WP2S18C03_20530	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_20540	ENOG4105F5W	AtP-binding protein
WP2S18C03_20570	ENOG4105W5Q	DNA repair protein (RadC
WP2S18C03_20680	ENOG4108ZQS	transposase
WP2S18C03_20700	ENOG4105E3S	small subunit
WP2S18C03_20710	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
WP2S18C03_20720	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
WP2S18C03_20730	ENOG4105DPX	Hydrogenase, large subunit
WP2S18C03_20740	ENOG4108USZ	hydrogenase
WP2S18C03_20750	ENOG4108WGS	hydrogenase 2-specific chaperone
WP2S18C03_20770	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_20780	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_20790	ENOG4105C3U	ABC transporter
WP2S18C03_20800	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_20810	ENOG4107RSS	Hydrogenase accessory protein HypB
WP2S18C03_20830	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
WP2S18C03_20840	ENOG4105C45	hydrogenase expression formation protein (HypE)
WP2S18C03_20850	ENOG4105CQS	hydrogenase expression formation protein HypD
WP2S18C03_20860	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
WP2S18C03_20880	ENOG4105EM7	Selenocysteine-specific translation elongation factor
WP2S18C03_20890	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
WP2S18C03_20900	ENOG4108MG9	hydrogenase 3 maturation protease
WP2S18C03_20910	ENOG4105I6X	formate hydrogenlyase maturation
WP2S18C03_20920	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
WP2S18C03_20940	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WP2S18C03_20950	ENOG4107TDF	Formate hydrogenlyase subunit 4
WP2S18C03_20960	ENOG4108JPZ	Monovalent cation H antiporter subunit D
WP2S18C03_20970	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
WP2S18C03_20980	ENOG4105DFH	Transport of potassium into the cell (By similarity)
WP2S18C03_20990	ENOG4105ESI	atpase involved in dna repair
WP2S18C03_21000	ENOG410600T	transposase
WP2S18C03_21020	ENOG4108RC0	Electron transport protein
WP2S18C03_21060	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
WP2S18C03_21070	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
WP2S18C03_21080	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
WP2S18C03_21090	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
WP2S18C03_21100	ENOG4105C0F	tryptophanase EC 4.1.99.1
WP2S18C03_21110	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
WP2S18C03_21120	ENOG41067MG	lrgb family
WP2S18C03_21140	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
WP2S18C03_21160	ENOG4105CJB	Exodeoxyribonuclease I
WP2S18C03_21200	ENOG4105EQR	Transposase IS116 IS110 IS902
WP2S18C03_21210	ENOG4105F5W	AtP-binding protein
WP2S18C03_21220	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_21250	ENOG4108DMF	Cytochrome C biogenesis protein
WP2S18C03_21260	ENOG4107QX9	Thiol disulfide interChange protein
WP2S18C03_21270	ENOG4105DA4	cytochrome c-type biogenesis protein
WP2S18C03_21280	ENOG4105DVI	reductase, NrfD
WP2S18C03_21290	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
WP2S18C03_21300	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
WP2S18C03_21350	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
WP2S18C03_21360	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
WP2S18C03_21370	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
WP2S18C03_21390	ENOG4105K5B	UPF0225 protein
WP2S18C03_21400	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_21410	ENOG4105E2R	ROK family
WP2S18C03_21420	ENOG4106IUH	DTW domain containing protein
WP2S18C03_21430	ENOG4105EJ9	Membrane
WP2S18C03_21440	ENOG4105VP0	transcriptional regulator, lysR family
WP2S18C03_21480	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
WP2S18C03_21510	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
WP2S18C03_21550	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
WP2S18C03_21560	ENOG4105WD1	Membrane
WP2S18C03_21570	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
WP2S18C03_21580	ENOG4107QMP	dna polymerase iii subunits gamma and tau
WP2S18C03_21590	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
WP2S18C03_21640	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
WP2S18C03_21660	ENOG4105DUM	transcriptional regulator, lysR family
WP2S18C03_21680	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
WP2S18C03_21690	ENOG4105D1S	lipid A biosynthesis
WP2S18C03_21730	ENOG4105CQ2	DNA polymerase
WP2S18C03_21760	ENOG4108VKG	metal-dependent hydrolase
WP2S18C03_21790	ENOG4105CEE	C4-dicarboxylate transporter
WP2S18C03_21820	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
WP2S18C03_21830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
WP2S18C03_21840	ENOG4105D0C	transport protein
WP2S18C03_21850	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
WP2S18C03_21870	ENOG4105DQR	SNARE associated Golgi
WP2S18C03_21880	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
WP2S18C03_21890	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
WP2S18C03_21920	ENOG4108VWS	Yaeq family
WP2S18C03_21940	ENOG4108JUB	Transcriptional regulator
WP2S18C03_21950	ENOG4107QI1	Mate efflux family protein
WP2S18C03_21960	ENOG4105W1I	UPF0253 protein
WP2S18C03_21980	ENOG4108R6K	riboflavin synthase, subunit alpha
WP2S18C03_22010	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
WP2S18C03_22020	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
WP2S18C03_22030	ENOG4108SXK	Transporter Drug Metabolite Exporter family
WP2S18C03_22040	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
WP2S18C03_22110	ENOG4105XW2	UPF0263 protein
WP2S18C03_22120	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
WP2S18C03_22130	ENOG4108W5H	UPF0263 protein
WP2S18C03_22140	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
WP2S18C03_22150	ENOG4107QMS	site-determining protein
WP2S18C03_22160	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
WP2S18C03_22170	ENOG4105VNG	YcgL domain-containing protein
WP2S18C03_22200	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
WP2S18C03_22240	ENOG4105CVJ	phosphoglycerate mutase
WP2S18C03_22250	ENOG4105BZU	Histidine kinase
WP2S18C03_22260	ENOG4108DG9	Smr protein MutS2
WP2S18C03_22270	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
WP2S18C03_22280	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
WP2S18C03_22300	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_22310	ENOG4105WJG	Glutathione
WP2S18C03_22340	ENOG4105E0U	tyrosine-specific transport protein
WP2S18C03_22350	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_22360	ENOG4105F5W	AtP-binding protein
WP2S18C03_22370	ENOG4105E0U	tyrosine-specific transport protein
WP2S18C03_22380	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
WP2S18C03_22390	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
WP2S18C03_22400	ENOG4105DE4	1-phosphofructokinase
WP2S18C03_22410	ENOG4105DM4	PTS System
WP2S18C03_22420	ENOG4105XZD	Fe-S protein
WP2S18C03_22430	ENOG4105CA3	membrane-bound lytic murein transglycosylase
WP2S18C03_22440	ENOG4105XPH	Ferredoxin
WP2S18C03_22450	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
WP2S18C03_22460	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
WP2S18C03_22470	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
WP2S18C03_22480	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
WP2S18C03_22490	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WP2S18C03_22540	ENOG4105C22	threonyL-tRNA synthetase
WP2S18C03_22550	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
WP2S18C03_22560	ENOG41083UC	50s ribosomal protein L35
WP2S18C03_22570	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
WP2S18C03_22580	ENOG4108Z33	Thiol disulfide Interchange Protein
WP2S18C03_22590	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
WP2S18C03_22600	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
WP2S18C03_22610	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
WP2S18C03_22630	ENOG4105BZU	Histidine kinase
WP2S18C03_22670	ENOG4105ETE	Transcriptional regulator (LacI family
WP2S18C03_22680	ENOG4108RVA	ribokinase
WP2S18C03_22690	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
WP2S18C03_22700	ENOG4105CNN	ABC, transporter
WP2S18C03_22710	ENOG4105C2J	ABC transporter
WP2S18C03_22720	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
WP2S18C03_22730	ENOG4108K3A	Glutathione S-transferase
WP2S18C03_22770	ENOG4108HM4	ABC transporter
WP2S18C03_22780	ENOG4105D38	putrescine abc transporter
WP2S18C03_22800	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_22830	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
WP2S18C03_22840	ENOG4105Q9Y	Universal stress protein
WP2S18C03_22850	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
WP2S18C03_22900	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
WP2S18C03_22930	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
WP2S18C03_22950	ENOG4108ZGC	gaf domain protein
WP2S18C03_22960	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
WP2S18C03_22970	ENOG4105CN1	protease
WP2S18C03_22980	ENOG4105CD8	aminopeptidase N
WP2S18C03_23000	ENOG4105C7I	Dehydrogenase
WP2S18C03_23010	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
WP2S18C03_23020	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
WP2S18C03_23030	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_23050	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
WP2S18C03_23060	ENOG4105BZU	Histidine kinase
WP2S18C03_23110	ENOG4108C33	Resolvase
WP2S18C03_23150	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_23170	ENOG4105BZU	Histidine kinase
WP2S18C03_23180	ENOG4108V3W	Chemotaxis protein, CheW
WP2S18C03_23190	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_23200	ENOG4105CBS	Chea signal transduction histidine kinase
WP2S18C03_23260	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
WP2S18C03_23280	ENOG4105C5H	ABC transporter
WP2S18C03_23290	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
WP2S18C03_23300	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
WP2S18C03_23310	ENOG4105DAN	ATP-dependent protease
WP2S18C03_23350	ENOG4105F5W	AtP-binding protein
WP2S18C03_23360	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_23380	ENOG4105X2V	dna damage-inducible protein
WP2S18C03_23400	ENOG4105PDP	Short chain dehydrogenase
WP2S18C03_23430	ENOG4108IG5	Transcriptional regulator
WP2S18C03_23450	ENOG4105D8T	Acyltransferase
WP2S18C03_23480	ENOG4105DXD	2-methylcitrate dehydratase
WP2S18C03_23490	ENOG4105BZN	citrate synthase
WP2S18C03_23500	ENOG4105CR4	methylisocitrate lyase
WP2S18C03_23520	ENOG4105F1S	paraquat-inducible protein a
WP2S18C03_23530	ENOG4105DY2	Paraquat-inducible protein b
WP2S18C03_23540	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WP2S18C03_23560	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_23590	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WP2S18C03_23620	ENOG4105F8V	Hydrolase, tatD family
WP2S18C03_23630	ENOG4107QRG	dna polymerase iii
WP2S18C03_23640	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
WP2S18C03_23650	ENOG4105HHA	aminodeoxychorismate lyase
WP2S18C03_23660	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
WP2S18C03_23670	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
WP2S18C03_23680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
WP2S18C03_23690	ENOG4105CHR	reductase
WP2S18C03_23700	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
WP2S18C03_23710	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
WP2S18C03_23720	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
WP2S18C03_23730	ENOG4105VGS	50s ribosomal protein l32
WP2S18C03_23740	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
WP2S18C03_23750	ENOG4108UHJ	MAF-like protein
WP2S18C03_23780	ENOG4105EI2	Pseudouridine synthase
WP2S18C03_23790	ENOG4105C03	ribonuclease
WP2S18C03_23800	ENOG4105CJ3	phosphate transporter
WP2S18C03_23810	ENOG4105DHP	deoxycytidine triphosphate deaminase
WP2S18C03_23820	ENOG4105DBI	uridine monophosphokinase
WP2S18C03_23830	ENOG4105D1F	ATP-binding protein
WP2S18C03_23840	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
WP2S18C03_23860	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
WP2S18C03_23870	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_23880	ENOG4105DR4	Methyltransferase
WP2S18C03_23890	ENOG4105FAT	Acyl-transferase
WP2S18C03_23900	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
WP2S18C03_23910	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
WP2S18C03_23920	ENOG4105C5X	domain protein
WP2S18C03_23940	ENOG4105CEY	Amp-dependent synthetase and ligase
WP2S18C03_23950	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
WP2S18C03_23970	ENOG41072GX	Peptidase M22 Glycoprotease
WP2S18C03_23980	ENOG4105DVT	helicase
WP2S18C03_24000	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
WP2S18C03_24010	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
WP2S18C03_24020	ENOG4105CIH	Imidazole acetol-phosphate transaminase
WP2S18C03_24030	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
WP2S18C03_24040	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
WP2S18C03_24050	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
WP2S18C03_24060	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
WP2S18C03_24070	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
WP2S18C03_24110	ENOG4105BZU	Histidine kinase
WP2S18C03_24120	ENOG4105CEY	Amp-dependent synthetase and ligase
WP2S18C03_24140	ENOG4107MBR	17 kDa surface antigen
WP2S18C03_24150	ENOG4108UTP	(2Fe-2S)-binding domain protein
WP2S18C03_24160	ENOG4108HR6	Dehydrogenase
WP2S18C03_24170	ENOG4105C7W	Xanthine dehydrogenase
WP2S18C03_24180	ENOG4105C7N	Xanthine uracil vitamin C permease
WP2S18C03_24190	ENOG4107QUY	Guanine deaminase
WP2S18C03_24200	ENOG4105C2W	permease
WP2S18C03_24210	ENOG4105C7W	Xanthine dehydrogenase
WP2S18C03_24220	ENOG410873Y	FAD binding domain in molybdopterin dehydrogenase
WP2S18C03_24230	ENOG4107UUR	Chlorohydrolase aminohydrolase
WP2S18C03_24240	ENOG4105BZ8	glutamate synthase
WP2S18C03_24250	ENOG4105MFX	4-diphosphocytidyl-2c-methyl-d-erythritol synthase
WP2S18C03_24260	ENOG4105MJ6	selenium-dependent hydroxylase accessory protein YqeC
WP2S18C03_24270	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
WP2S18C03_24280	ENOG4108Q5Y	Membrane
WP2S18C03_24290	ENOG4105C5B	carbamate kinase
WP2S18C03_24310	ENOG4107S4Y	M20 DapE family protein YgeY
WP2S18C03_24320	ENOG4107RCH	Diaminopropionate ammonia-lyase
WP2S18C03_24330	ENOG4105IW6	Carbamoyltransferase
WP2S18C03_24370	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
WP2S18C03_24390	ENOG4105K6T	rare lipoprotein A
WP2S18C03_24400	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
WP2S18C03_24410	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
WP2S18C03_24420	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
WP2S18C03_24430	ENOG4106371	Methyltransferase
WP2S18C03_24440	ENOG4107S90	membrAne
WP2S18C03_24460	ENOG4105CTQ	phosphohexokinase
WP2S18C03_24480	ENOG4107QJT	sodium dicarboxylate symporter
WP2S18C03_24490	ENOG4105NBK	UPF0345 protein
WP2S18C03_24500	ENOG4105EJQ	L-serine dehydratase
WP2S18C03_24510	ENOG4105EJQ	L-serine dehydratase
WP2S18C03_24550	ENOG4105C44	Serine transporter
WP2S18C03_24590	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_24600	ENOG4105F5W	AtP-binding protein
WP2S18C03_24620	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
WP2S18C03_24630	ENOG4105C9U	ATP-dependent DNA helicase RecQ
WP2S18C03_24640	ENOG4105CYN	Serine protein kinase
WP2S18C03_24650	ENOG4106AKX	UPF0229 protein
WP2S18C03_24660	ENOG4105ED1	spovr family
WP2S18C03_24670	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
WP2S18C03_24680	ENOG4105CHU	acetyl-coa acetyltransferase
WP2S18C03_24690	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
WP2S18C03_24760	ENOG4105EMN	RNA polymerase sigma factor
WP2S18C03_24780	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
WP2S18C03_24790	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
WP2S18C03_24800	ENOG4105D58	Diguanylate phosphodiesterase
WP2S18C03_24810	ENOG4105CHU	acetyl-coa acetyltransferase
WP2S18C03_24830	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
WP2S18C03_24850	ENOG4105CQ7	ATP-dependent helicase
WP2S18C03_24870	ENOG4105DHT	Metal Dependent Phosphohydrolase
WP2S18C03_24890	ENOG4105EQR	Transposase IS116 IS110 IS902
WP2S18C03_24900	ENOG4105F5W	AtP-binding protein
WP2S18C03_24910	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_24980	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
WP2S18C03_25010	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
WP2S18C03_25100	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
WP2S18C03_25110	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
WP2S18C03_25120	ENOG4105C7S	Dehydrogenase
WP2S18C03_25130	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
WP2S18C03_25140	ENOG4105E33	succinate dehydrogenase
WP2S18C03_25150	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
WP2S18C03_25160	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
WP2S18C03_25170	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
WP2S18C03_25190	ENOG4105BZN	citrate synthase
WP2S18C03_25210	ENOG4105K5X	acetyltransferase
WP2S18C03_25260	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
WP2S18C03_25290	ENOG4105WQ3	Rna-binding protein
WP2S18C03_25310	ENOG4105BZ1	(ABC) transporter
WP2S18C03_25320	ENOG4105BZ1	(ABC) transporter
WP2S18C03_25330	ENOG4105BZU	Histidine kinase
WP2S18C03_25340	ENOG4105K63	Thioredoxin
WP2S18C03_25350	ENOG4105C8P	)-transporter
WP2S18C03_25400	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_25410	ENOG4105F5W	AtP-binding protein
WP2S18C03_25420	ENOG4105C6N	Formate acetyltransferase
WP2S18C03_25430	ENOG4105TMB	Formate nitrite transporter
WP2S18C03_25440	ENOG4105DDY	UPF0142 protein ycaO
WP2S18C03_25450	ENOG4105CS2	ec 3.2.1.21
WP2S18C03_25460	ENOG4108KB2	LysR family Transcriptional regulator
WP2S18C03_25490	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
WP2S18C03_25500	ENOG4105DZ2	Transcriptional regulator
WP2S18C03_25510	ENOG4105EXG	Transcriptional regulator
WP2S18C03_25520	ENOG4105CHJ	isochorismatase hydrolase
WP2S18C03_25530	ENOG4105EUB	pirin domain protein
WP2S18C03_25550	ENOG4105CR8	Transcriptional regulator
WP2S18C03_25560	ENOG4108RYK	Nad-dependent epimerase dehydratase
WP2S18C03_25590	ENOG4108IQE	Amp-dependent synthetase and ligase
WP2S18C03_25600	ENOG4105MH2	YfcL protein
WP2S18C03_25620	ENOG4105EE5	Membrane protein terC
WP2S18C03_25630	ENOG41090EK	ompa motb domain protein
WP2S18C03_25640	ENOG4105BZU	Histidine kinase
WP2S18C03_25650	ENOG4105BZU	Histidine kinase
WP2S18C03_25680	ENOG41090A4	Pterin carbinolamine dehydratase
WP2S18C03_25690	ENOG41090A4	Pterin carbinolamine dehydratase
WP2S18C03_25700	ENOG4105MIR	Phenylalanine 4-monooxygenase
WP2S18C03_25710	ENOG4106K28	UPF0283 membrane protein
WP2S18C03_25720	ENOG4105CM6	amino acid regulated cytosolic protein
WP2S18C03_25740	ENOG4105YYT	phage shock protein B
WP2S18C03_25750	ENOG41087YS	Phage shock protein A
WP2S18C03_25760	ENOG4105E51	psp operon transcriptional activator
WP2S18C03_25770	ENOG4108J59	Extracellular solute-binding protein, family 5
WP2S18C03_25780	ENOG4108EKA	peptide transport system, permease
WP2S18C03_25790	ENOG4108EU3	peptide transport system, permease
WP2S18C03_25800	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
WP2S18C03_25810	ENOG4108JQ2	peptide transport system atp-binding protein
WP2S18C03_25820	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
WP2S18C03_25830	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
WP2S18C03_25840	ENOG4108RMJ	sensory transduction regulator
WP2S18C03_25860	ENOG4107104	thymidine kinase
WP2S18C03_25870	ENOG4107S6Z	Na H antiporter
WP2S18C03_25890	ENOG4108WBT	adenosyltransferase
WP2S18C03_25900	ENOG4105VRT	cytoplasmic protein
WP2S18C03_25910	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
WP2S18C03_25920	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
WP2S18C03_25950	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
WP2S18C03_25960	ENOG4105CFV	Tetratricopeptide repeat protein
WP2S18C03_25980	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
WP2S18C03_25990	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
WP2S18C03_26000	ENOG4105CAT	Cytidine monophosphate kinase
WP2S18C03_26010	ENOG4108JEN	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
WP2S18C03_26020	ENOG4107R11	Transcriptional regulator
WP2S18C03_26030	ENOG4105DUM	transcriptional regulator, lysR family
WP2S18C03_26040	ENOG4108SC4	)-transporter
WP2S18C03_26070	ENOG4108DBC	nitroreductase
WP2S18C03_26080	ENOG4105CFC	Transporter
WP2S18C03_26090	ENOG4105BZU	Histidine kinase
WP2S18C03_26100	ENOG4105CBN	LysR family transcriptional regulator
WP2S18C03_26110	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
WP2S18C03_26130	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_26150	ENOG4108RU0	short-chain dehydrogenase reductase
WP2S18C03_26170	ENOG4107RGM	aldo keto reductase
WP2S18C03_26180	ENOG4105VFU	Rna-binding protein
WP2S18C03_26210	ENOG4105E5Q	amino acid AbC transporter
WP2S18C03_26220	ENOG4106TNF	Periplasmic binding protein
WP2S18C03_26230	ENOG4105EZ7	amino acid ABC transporter
WP2S18C03_26240	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
WP2S18C03_26260	ENOG4105HA9	of methanol dehydrogenase type
WP2S18C03_26280	ENOG4105E14	MotA TolQ exbB proton channel
WP2S18C03_26290	ENOG4105ER2	Ompa motb domain protein
WP2S18C03_26300	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
WP2S18C03_26310	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WP2S18C03_26320	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WP2S18C03_26330	ENOG4105GKE	subunit e
WP2S18C03_26340	ENOG4107QIZ	NADH dehydrogenase
WP2S18C03_26350	ENOG4108IEH	NADH dehydrogenase subunit g
WP2S18C03_26360	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
WP2S18C03_26370	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WP2S18C03_26380	ENOG4107UFS	subunit j
WP2S18C03_26390	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WP2S18C03_26400	ENOG4105D65	subunit l
WP2S18C03_26410	ENOG4105C8S	subunit m
WP2S18C03_26420	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
WP2S18C03_26430	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
WP2S18C03_26440	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
WP2S18C03_26460	ENOG4105VPD	cellular component movement
WP2S18C03_26470	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
WP2S18C03_26480	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
WP2S18C03_26490	ENOG4105N21	Membrane
WP2S18C03_26500	ENOG4105CUT	histidyl-tRNA synthetase
WP2S18C03_26510	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
WP2S18C03_26520	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
WP2S18C03_26540	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
WP2S18C03_26550	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
WP2S18C03_26580	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
WP2S18C03_26600	ENOG4108ZIT	Ferredoxin, 2FE-2S
WP2S18C03_26610	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
WP2S18C03_26620	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
WP2S18C03_26630	ENOG4108Z4V	iron-sulfur cluster assembly
WP2S18C03_26640	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
WP2S18C03_26650	ENOG4105C3J	Cysteine desulfurase
WP2S18C03_26660	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
WP2S18C03_26670	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
WP2S18C03_26740	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
WP2S18C03_26750	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
WP2S18C03_26760	ENOG4105VIE	preprotein translocase, subunit YajC
WP2S18C03_26770	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
WP2S18C03_26780	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
WP2S18C03_26790	ENOG4108IJ8	ABC transporter
WP2S18C03_26800	ENOG4105D3R	alkyl hydroperoxide reductase
WP2S18C03_26860	ENOG4105F5W	AtP-binding protein
WP2S18C03_26870	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_26940	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
WP2S18C03_26950	ENOG4108JJA	ABC, transporter
WP2S18C03_26960	ENOG4105N5T	Radical SAM Protein
WP2S18C03_26970	ENOG4105CBC	glutamate synthase
WP2S18C03_26980	ENOG4105BZ8	glutamate synthase
WP2S18C03_26990	ENOG4105CDA	abc transporter atp-binding protein
WP2S18C03_27000	ENOG4105E5Q	amino acid AbC transporter
WP2S18C03_27010	ENOG4105EAB	amino acid AbC transporter
WP2S18C03_27040	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_27070	ENOG4105CE1	Ferrous iron transport protein b
WP2S18C03_27090	ENOG4108ZJT	translation initiation factor, Sui1
WP2S18C03_27160	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
WP2S18C03_27220	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
WP2S18C03_27230	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
WP2S18C03_27240	ENOG4105Y3U	Transglycosylase-associated protein
WP2S18C03_27250	ENOG4105DHQ	Histidine kinase
WP2S18C03_27420	ENOG4105F5W	AtP-binding protein
WP2S18C03_27430	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_27470	ENOG4105F5W	AtP-binding protein
WP2S18C03_27480	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_27490	ENOG4107R08	Integrase
WP2S18C03_27570	ENOG4108MIB	
WP2S18C03_27740	ENOG4105VTR	Integrase
WP2S18C03_27760	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
WP2S18C03_27770	ENOG4105WH1	Two component transcriptional regulator luxr family
WP2S18C03_27780	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_27790	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
WP2S18C03_27800	ENOG4105W49	UPF0434 protein
WP2S18C03_27810	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
WP2S18C03_27830	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
WP2S18C03_27860	ENOG4105CGF	Aromatic amino acid aminotransferase
WP2S18C03_27880	ENOG4105CVI	Transcriptional regulator
WP2S18C03_27890	ENOG4108WFC	UPF0438 protein yifE
WP2S18C03_27900	ENOG4108QSZ	General inhibitor of pancreatic serine proteases inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases (By similarity)
WP2S18C03_27910	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
WP2S18C03_27920	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
WP2S18C03_27930	ENOG4105E98	transcriptional regulator DeoR family
WP2S18C03_27940	ENOG4105CXY	transporter
WP2S18C03_27950	ENOG4105F5W	AtP-binding protein
WP2S18C03_27960	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_27970	ENOG4105CXY	transporter
WP2S18C03_28000	ENOG4105CXY	transporter
WP2S18C03_28010	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
WP2S18C03_28020	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
WP2S18C03_28030	ENOG41069D7	Methyl-accepting chemotaxis
WP2S18C03_28050	ENOG4105HEI	LysR family (Transcriptional regulator
WP2S18C03_28090	ENOG4105CV8	reductase
WP2S18C03_28100	ENOG4105F27	Major Facilitator
WP2S18C03_28110	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
WP2S18C03_28140	ENOG4105E18	UPF0276 protein
WP2S18C03_28180	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
WP2S18C03_28190	ENOG4105C4M	(Ubiquinol oxidase) subunit I
WP2S18C03_28200	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
WP2S18C03_28220	ENOG4108Q2J	Inner membrane protein YebE
WP2S18C03_28230	ENOG4105NAU	thioesterase Superfamily protein
WP2S18C03_28240	ENOG4106428	Protein of unknown function (DUF2496)
WP2S18C03_28250	ENOG4105C5Q	Transcriptional regulator
WP2S18C03_28270	ENOG4105DJ2	Major Facilitator Superfamily
WP2S18C03_28280	ENOG4105FE9	pseudouridine synthase
WP2S18C03_28320	ENOG4105DGN	Electron transport complex
WP2S18C03_28330	ENOG4108R3D	Electron transport complex
WP2S18C03_28350	ENOG4105D6A	Electron transport complex
WP2S18C03_28380	ENOG4105CSM	endonuclease III
WP2S18C03_28390	ENOG4108UYE	Lactoylglutathione lyase
WP2S18C03_28400	ENOG4105EIY	sodium-type flagellar protein motY
WP2S18C03_28420	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
WP2S18C03_28430	ENOG4107QS8	(LipO)protein
WP2S18C03_28450	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
WP2S18C03_28460	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
WP2S18C03_28470	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
WP2S18C03_28490	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
WP2S18C03_28500	ENOG4105E66	phosphoriboisomerase A
WP2S18C03_28510	ENOG4108JQ1	Dehydrogenase
WP2S18C03_28520	ENOG41080IJ	Diacylglycerol kinase
WP2S18C03_28530	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
WP2S18C03_28550	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
WP2S18C03_28580	ENOG4105CZX	twitching motility protein
WP2S18C03_28600	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
WP2S18C03_28610	ENOG4105DU1	integral membrane protein, terc
WP2S18C03_28620	ENOG4108JQ7	(ABC) transporter
WP2S18C03_28630	ENOG4105C3U	ABC transporter
WP2S18C03_28640	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_28650	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_28660	ENOG4107QSI	ABC, transporter
WP2S18C03_28670	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
WP2S18C03_28680	ENOG4105C0A	alcohol dehydrogenase
WP2S18C03_28690	ENOG4105CDY	transcriptional regulatory protein
WP2S18C03_28700	ENOG4105C9M	aspartyl-trna synthetase
WP2S18C03_28720	ENOG41081XQ	Conserved Protein
WP2S18C03_28730	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
WP2S18C03_28740	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
WP2S18C03_28800	ENOG4105D3R	alkyl hydroperoxide reductase
WP2S18C03_28810	ENOG4105C5Q	Transcriptional regulator
WP2S18C03_28820	ENOG4108QBX	(LipO)protein
WP2S18C03_28840	ENOG4108HMX	isocitrate dehydrogenase (NADP)
WP2S18C03_28850	ENOG4106R3P	AraC family transcriptional regulator
WP2S18C03_28860	ENOG4105EIP	mannose-6-phosphate isomerase
WP2S18C03_28900	ENOG4105DM4	PTS System
WP2S18C03_28930	ENOG4105KAF	membrAne
WP2S18C03_28940	ENOG4107RDB	Major Facilitator
WP2S18C03_28950	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
WP2S18C03_28960	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
WP2S18C03_28970	ENOG4105CCU	oxidase (Subunit III)
WP2S18C03_28980	ENOG4105BZ9	Cytochrome C oxidase, subunit I
WP2S18C03_28990	ENOG4105E2S	oxidase) subunit II
WP2S18C03_29020	ENOG4107TJ9	Cytochrome
WP2S18C03_29060	ENOG4107RGH	Aldehyde dehydrogenase
WP2S18C03_29070	ENOG4107Z3H	Transcriptional regulator, TetR family
WP2S18C03_29090	ENOG4105C0A	alcohol dehydrogenase
WP2S18C03_29130	ENOG4105UQX	Mate efflux family protein
WP2S18C03_29150	ENOG4105Z2P	Protein of unknown function (DUF465)
WP2S18C03_29160	ENOG4108YXG	UPF0502 protein
WP2S18C03_29220	ENOG4105CGK	Exodeoxyribonuclease III
WP2S18C03_29260	ENOG4108JJB	ABC transporter
WP2S18C03_29270	ENOG4108JJB	ABC transporter
WP2S18C03_29310	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
WP2S18C03_29320	ENOG4108IJF	Heavy metal efflux pump, CzcA
WP2S18C03_29340	ENOG4105S10	periplasmic binding protein
WP2S18C03_29350	ENOG4105E0A	ABC, transporter
WP2S18C03_29360	ENOG4105TVJ	transport system, permease
WP2S18C03_29370	ENOG4105DQ5	transport system permease protein
WP2S18C03_29380	ENOG4105Q26	Siderophore-interacting protein
WP2S18C03_29390	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
WP2S18C03_29410	ENOG4107RZZ	dna polymerase iii epsilon subunit
WP2S18C03_29420	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
WP2S18C03_29430	ENOG4105D1A	Methyltransferase
WP2S18C03_29440	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
WP2S18C03_29450	ENOG4105E9H	Lytic Murein transglycosylase
WP2S18C03_29480	ENOG4105KR1	Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity)
WP2S18C03_29500	ENOG4105DFP	Integrase
WP2S18C03_29520	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_29530	ENOG4105F5W	AtP-binding protein
WP2S18C03_29540	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
WP2S18C03_29560	ENOG4105C8P	)-transporter
WP2S18C03_29580	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
WP2S18C03_29590	ENOG4107TT5	NLP P60 protein
WP2S18C03_29600	ENOG4107YAK	holo-(acyl carrier protein) synthase 2
WP2S18C03_29610	ENOG4107QR8	Thioredoxin
WP2S18C03_29630	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
WP2S18C03_29640	ENOG4105CIY	formyltetrahydrofolate deformylase
WP2S18C03_29690	ENOG4105E4C	Lytic transglycosylase catalytic
WP2S18C03_29700	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
WP2S18C03_29720	ENOG4105CHM	Aminotransferase
WP2S18C03_29740	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
WP2S18C03_29750	ENOG4105RKW	reductase (By
WP2S18C03_29760	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
WP2S18C03_29780	ENOG4105CVJ	phosphoglycerate mutase
WP2S18C03_29790	ENOG4105WWK	YheO domain protein
WP2S18C03_29800	ENOG4105CEM	UPF0597 protein
WP2S18C03_29810	ENOG4105KME	endoribonuclease L-psp
WP2S18C03_29820	ENOG4105C44	Serine transporter
WP2S18C03_29860	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
WP2S18C03_29870	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
WP2S18C03_29920	ENOG4108YYC	ycei family
WP2S18C03_29930	ENOG4105CC0	LysR family Transcriptional regulator
WP2S18C03_29950	ENOG4105CKU	formyltetrahydrofolate synthetase
WP2S18C03_29960	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_29970	ENOG4105EUJ	GTP cyclohydrolase i
WP2S18C03_29980	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
WP2S18C03_29990	ENOG4105D06	uba thif-type nad fad binding protein
WP2S18C03_30000	ENOG41082A2	Alpha beta hydrolase
WP2S18C03_30010	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_30020	ENOG4105E0C	molybdate abc transporter
WP2S18C03_30030	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
WP2S18C03_30040	ENOG4108ZAF	Molybdopterin
WP2S18C03_30060	ENOG4105M00	molybdopterin converting factor, subunit 1
WP2S18C03_30070	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
WP2S18C03_30080	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
WP2S18C03_30090	ENOG4105CUW	cytochrome C-TYPE protein
WP2S18C03_30110	ENOG4105GXZ	Ferredoxin-type protein NapH
WP2S18C03_30120	ENOG4108BGM	Quinol dehydrogenase periplasmic component
WP2S18C03_30130	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
WP2S18C03_30160	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
WP2S18C03_30170	ENOG4105BZU	Histidine kinase
WP2S18C03_30180	ENOG4105WH1	Two component transcriptional regulator luxr family
WP2S18C03_30200	ENOG4105BZU	Histidine kinase
WP2S18C03_30220	ENOG4105CHW	UPF0052 protein
WP2S18C03_30240	ENOG4105E7A	Glutamine amidotransferase
WP2S18C03_30250	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
WP2S18C03_30260	ENOG4107QPN	acyl-Coa dehydrogenase
WP2S18C03_30270	ENOG4105CH2	amidohydrolase
WP2S18C03_30290	ENOG4108Z1B	Cyclase dehydrase
WP2S18C03_30300	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
WP2S18C03_30650	ENOG4108ZUE	Phage regulatory protein rha
WP2S18C03_30830	ENOG41076J9	exonuclease VIII
WP2S18C03_30910	ENOG4105DH7	May be involved in recombination (By similarity)
WP2S18C03_31020	ENOG4107R08	Integrase
WP2S18C03_31030	ENOG4105DFP	Integrase
WP2S18C03_31080	ENOG4107QNK	)-transporter
WP2S18C03_31090	ENOG4107HQ7	repeat protein
WP2S18C03_31100	ENOG4108NZE	NAGC-like transcriptional regulator
WP2S18C03_31110	ENOG4108IEG	Formate dehydrogenase Alpha subunit
WP2S18C03_31220	ENOG4105C0D	helicase
WP2S18C03_31250	ENOG4107QMH	DNA methylase
WP2S18C03_31290	ENOG4108NVR	Methyl-accepting chemotaxis
WP2S18C03_31300	ENOG4105F2I	Transposase
WP2S18C03_31310	ENOG4105BZU	Histidine kinase
WP2S18C03_31340	ENOG4105BZU	Histidine kinase
WP2S18C03_31380	ENOG410679B	prophage CP4-57 regulatory protein alpA
WP2S18C03_31390	ENOG4108P8R	
WP2S18C03_31400	ENOG4105JXR	Protein of unknown function (DUF3296)
WP2S18C03_31410	ENOG4107SSZ	Phosphatase
WP2S18C03_31430	ENOG4107QPN	acyl-Coa dehydrogenase
WP2S18C03_31440	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
WP2S18C03_31490	ENOG4105C87	Aminotransferase class I and II
WP2S18C03_31500	ENOG4105CI1	PTS System
WP2S18C03_31510	ENOG4107P2S	Transcriptional regulator
WP2S18C03_31580	ENOG4105DM4	PTS System
WP2S18C03_31590	ENOG4105CXY	transporter
WP2S18C03_31600	ENOG4108YRF	PTS System
WP2S18C03_31620	ENOG4108R99	pseudouridine synthase
WP2S18C03_31630	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
WP2S18C03_31640	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
WP2S18C03_31650	ENOG41075W9	High frequency lysogenization protein HflD homolog
WP2S18C03_31660	ENOG4107QTF	adenylosuccinate lyase
WP2S18C03_31670	ENOG4105EZE	Cupin 4 family protein
WP2S18C03_31730	ENOG4108KD5	ADP-ribosylation crystallin J1
WP2S18C03_31750	ENOG4108TFM	Kinase, PfkB family
WP2S18C03_31790	ENOG4108TGY	Glutathione S-transferase
WP2S18C03_31800	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
WP2S18C03_31840	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_31850	ENOG4105F5W	AtP-binding protein
WP2S18C03_31870	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
WP2S18C03_31880	ENOG4105C6N	Formate acetyltransferase
WP2S18C03_31900	ENOG4105C6N	Formate acetyltransferase
WP2S18C03_31910	ENOG4105KME	endoribonuclease L-psp
WP2S18C03_31940	ENOG4105F5W	AtP-binding protein
WP2S18C03_31950	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_31980	ENOG4108MST	Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system) (By similarity)
WP2S18C03_31990	ENOG4105C7B	Threonine dehydratase
WP2S18C03_32000	ENOG4105EQR	Transposase IS116 IS110 IS902
WP2S18C03_32020	ENOG4105M2J	Glutaredoxin
WP2S18C03_32030	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
WP2S18C03_32040	ENOG410903C	(LipO)protein
WP2S18C03_32060	ENOG4105KWW	Biogenesis protein
WP2S18C03_32070	ENOG4107QX9	Thiol disulfide interChange protein
WP2S18C03_32080	ENOG4105DA4	cytochrome c-type biogenesis protein
WP2S18C03_32090	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
WP2S18C03_32100	ENOG4105X3C	heme exporter protein
WP2S18C03_32110	ENOG41060IM	Heme exporter protein
WP2S18C03_32120	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
WP2S18C03_32160	ENOG4108V3W	Chemotaxis protein, CheW
WP2S18C03_32180	ENOG4107QJE	Chromosome Partitioning Protein
WP2S18C03_32190	ENOG4108SEK	ompa motb domain protein
WP2S18C03_32200	ENOG4105E14	MotA TolQ exbB proton channel
WP2S18C03_32210	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
WP2S18C03_32230	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
WP2S18C03_32240	ENOG4108VYJ	response regulator receiver protein
WP2S18C03_32250	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WP2S18C03_32270	ENOG4105FZW	flagellar biosynthesis regulator FlhF
WP2S18C03_32280	ENOG4105D7B	Flagellar biosynthesis protein flha
WP2S18C03_32290	ENOG4105D00	flagellar biosynthetic protein flhB
WP2S18C03_32300	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
WP2S18C03_32310	ENOG4105VS8	Flagellar biosynthetic protein fliq
WP2S18C03_32320	ENOG4105CN7	Flagellar biosynthetic protein FliP
WP2S18C03_32330	ENOG4105VTB	flagellar biosynthesis protein fliO
WP2S18C03_32340	ENOG4105DD5	Flagellar motor switch protein
WP2S18C03_32350	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
WP2S18C03_32390	ENOG4108JIR	Flagellum-specific ATP synthase
WP2S18C03_32410	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
WP2S18C03_32420	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
WP2S18C03_32430	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
WP2S18C03_32450	ENOG4105CA9	Pyruvate kinase
WP2S18C03_32460	ENOG4106KNT	transcriptional regulator
WP2S18C03_32530	ENOG4105C2W	permease
WP2S18C03_32560	ENOG4107R1I	NAD-dependent malic enzyme
WP2S18C03_32570	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
WP2S18C03_32590	ENOG4105QAX	Iron-sulfur
WP2S18C03_32600	ENOG4108IEG	Formate dehydrogenase Alpha subunit
WP2S18C03_32600	ENOG4108IEG	Formate dehydrogenase Alpha subunit
WP2S18C03_32670	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
WP2S18C03_32690	ENOG4105BZU	Histidine kinase
WP2S18C03_32700	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WP2S18C03_32720	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_32730	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
WP2S18C03_32740	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
WP2S18C03_32750	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
WP2S18C03_32760	ENOG4105DR8	Membrane
WP2S18C03_32770	ENOG4108ESY	Metal dependent phosphohydrolase
WP2S18C03_32780	ENOG4105F5W	AtP-binding protein
WP2S18C03_32790	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_32800	ENOG4108ESY	Metal dependent phosphohydrolase
WP2S18C03_32820	ENOG4107SDU	Methyl-accepting chemotaxis
WP2S18C03_32840	ENOG4105XIQ	Protein of unknown function (DUF2517)
WP2S18C03_32870	ENOG4108J59	Extracellular solute-binding protein, family 5
WP2S18C03_32890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_32910	ENOG4108JQ7	(ABC) transporter
WP2S18C03_32930	ENOG4105RD7	BadF BadG BcrA BcrD
WP2S18C03_32940	ENOG4105E2D	ec 3.2.1.52
WP2S18C03_32990	ENOG4108ZQS	transposase
WP2S18C03_33020	ENOG4105E4G	Type IV pilus
WP2S18C03_33030	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
WP2S18C03_33040	ENOG4105D49	3-dehydroquinate synthase
WP2S18C03_33060	ENOG4105DFE	Dna adenine methylase
WP2S18C03_33070	ENOG4105DJV	ribulose-phosphate 3-epimerase
WP2S18C03_33080	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
WP2S18C03_33090	ENOG4105C31	Tryptophanyl-tRNA synthetase
WP2S18C03_33120	ENOG4105C8Y	Acetylornithine aminotransferase
WP2S18C03_33140	ENOG4105C26	Dehydrogenase
WP2S18C03_33160	ENOG4107VXZ	Hydrolase
WP2S18C03_33180	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
WP2S18C03_33190	ENOG4105CG3	alpha amylase, catalytic region
WP2S18C03_33230	ENOG4108I5U	Uridine phosphorylase
WP2S18C03_33240	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
WP2S18C03_33250	ENOG4107QWE	)-transporter
WP2S18C03_33280	ENOG4108W5M	transcriptional regulator
WP2S18C03_33290	ENOG4107TYH	extracellular solute-binding protein family 1
WP2S18C03_33300	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
WP2S18C03_33310	ENOG4105D81	ABC transporter, permease
WP2S18C03_33320	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
WP2S18C03_33330	ENOG4105C26	Dehydrogenase
WP2S18C03_33340	ENOG4105C3G	gtp-binding protein
WP2S18C03_33350	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
WP2S18C03_33360	ENOG4105CGH	5'-nucleotidase
WP2S18C03_33370	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
WP2S18C03_33380	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
WP2S18C03_33390	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
WP2S18C03_33400	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
WP2S18C03_33410	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
WP2S18C03_33420	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
WP2S18C03_33440	ENOG41063JG	Transcriptional regulator
WP2S18C03_33450	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
WP2S18C03_33460	ENOG4105CK2	sodium dicarboxylate symporter
WP2S18C03_33470	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
WP2S18C03_33490	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
WP2S18C03_33510	ENOG4107WCA	isomerase
WP2S18C03_33530	ENOG4108V1U	phospholipid-binding protein
WP2S18C03_33540	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
WP2S18C03_33570	ENOG4105C87	Aminotransferase class I and II
WP2S18C03_33590	ENOG4105C5Q	Transcriptional regulator
WP2S18C03_33600	ENOG4105UBK	short-chain dehydrogenase reductase
WP2S18C03_33610	ENOG4105ERU	peptidase
WP2S18C03_33620	ENOG4105E5W	Transporter
WP2S18C03_33630	ENOG4105BZU	Histidine kinase
WP2S18C03_33640	ENOG41090EX	DsrE family
WP2S18C03_33660	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
WP2S18C03_33670	ENOG4105CFP	Peptidase U32
WP2S18C03_33680	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
WP2S18C03_33720	ENOG410600T	transposase
WP2S18C03_33740	ENOG41068CG	regulatoR
WP2S18C03_33750	ENOG4105BZU	Histidine kinase
WP2S18C03_33770	ENOG4105EY2	Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2) (By similarity)
WP2S18C03_33780	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
WP2S18C03_33820	ENOG4108JQC	penicillin-binding protein 1A
WP2S18C03_33830	ENOG4105C5Q	Transcriptional regulator
WP2S18C03_33840	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_33870	ENOG4105EJC	lysr family transcriptional regulator
WP2S18C03_33890	ENOG4105DR5	peptidase
WP2S18C03_33910	ENOG4105EGS	Mechanosensitive ion channel
WP2S18C03_33920	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
WP2S18C03_33930	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_33980	ENOG4105E33	succinate dehydrogenase
WP2S18C03_33990	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
WP2S18C03_34000	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
WP2S18C03_34010	ENOG41074DU	domain protein
WP2S18C03_34020	ENOG4108P2H	Inner membrane protein YjiG
WP2S18C03_34030	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
WP2S18C03_34050	ENOG4105T0Z	Conserved Protein
WP2S18C03_34080	ENOG4105CJP	fad dependent oxidoreductase
WP2S18C03_34090	ENOG4105CJP	fad dependent oxidoreductase
WP2S18C03_34100	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
WP2S18C03_34140	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
WP2S18C03_34160	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
WP2S18C03_34170	ENOG4105DHQ	Histidine kinase
WP2S18C03_34190	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
WP2S18C03_34210	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
WP2S18C03_34230	ENOG4105C5I	Dehydrogenase
WP2S18C03_34250	ENOG4105DUM	transcriptional regulator, lysR family
WP2S18C03_34260	ENOG4105CPN	adenine deaminase
WP2S18C03_34280	ENOG4105CEE	C4-dicarboxylate transporter
WP2S18C03_34330	ENOG4106TD9	Diguanylate cyclase
WP2S18C03_34340	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
WP2S18C03_34360	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
WP2S18C03_34370	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
WP2S18C03_34380	ENOG4105C9A	Phoh family
WP2S18C03_34390	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
WP2S18C03_34400	ENOG4108JU5	Magnesium and cobalt efflux protein
WP2S18C03_34410	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
WP2S18C03_34440	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
WP2S18C03_34460	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
WP2S18C03_34470	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WP2S18C03_34480	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
WP2S18C03_34490	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
WP2S18C03_34520	ENOG4107PAI	alpha helical protein
WP2S18C03_34530	ENOG4105C8T	Leucyl-tRNA synthetase
WP2S18C03_34560	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
WP2S18C03_34570	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
WP2S18C03_34580	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
WP2S18C03_34590	ENOG4105CJN	penicillin-binding protein
WP2S18C03_34600	ENOG4105CNI	cell division protein FtsW
WP2S18C03_34610	ENOG4105CVE	Lytic murein transglycosylase
WP2S18C03_34620	ENOG4105K6T	rare lipoprotein A
WP2S18C03_34630	ENOG4105DZ1	carboxypeptidase
WP2S18C03_34640	ENOG4108Z43	UPF0250 protein
WP2S18C03_34650	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
WP2S18C03_34660	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
WP2S18C03_34700	ENOG4105VUT	cytoplasmic protein
WP2S18C03_34710	ENOG4105HDK	L-asparaginase
WP2S18C03_34720	ENOG4105D6U	Sodium Glutamate Symporter
WP2S18C03_34730	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_34740	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
WP2S18C03_34750	ENOG4105CRK	lysyL-tRNA synthetase
WP2S18C03_34760	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
WP2S18C03_34770	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
WP2S18C03_34780	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
WP2S18C03_34790	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
WP2S18C03_34820	ENOG4105DWK	Membrane
WP2S18C03_34840	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
WP2S18C03_34860	ENOG4105SUV	lipoprotein YgdR
WP2S18C03_34870	ENOG4107RM6	sulfurtransferase
WP2S18C03_34880	ENOG4105CSV	Glutaminase
WP2S18C03_34890	ENOG41090ED	Protein with unknown function (DUF469)
WP2S18C03_34900	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
WP2S18C03_34910	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
WP2S18C03_34920	ENOG4105BZU	Histidine kinase
WP2S18C03_34940	ENOG4105ECP	epimerase
WP2S18C03_34950	ENOG4105CV6	ABC transporter, permease
WP2S18C03_34960	ENOG4108I0Y	(ABC) transporter
WP2S18C03_34970	ENOG4108UJV	acyl-CoA thioesterase i
WP2S18C03_35020	ENOG4108M1A	Chitin-binding protein
WP2S18C03_35030	ENOG4108MA4	Peptidase M66
WP2S18C03_35050	ENOG4105BZU	Histidine kinase
WP2S18C03_35070	ENOG4105VMP	Transcriptional regulator
WP2S18C03_35090	ENOG4105D8G	Major Facilitator superfamily
WP2S18C03_35150	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
WP2S18C03_35160	ENOG41090JE	Utilization Protein
WP2S18C03_35180	ENOG4105EHG	Permease protein
WP2S18C03_35210	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
WP2S18C03_35220	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
WP2S18C03_35230	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
WP2S18C03_35240	ENOG4105CDU	Replicative dna helicase
WP2S18C03_35270	ENOG4105CGH	5'-nucleotidase
WP2S18C03_35310	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WP2S18C03_35320	ENOG4108V1T	peptidylprolyl cis-trans isomerase
WP2S18C03_35350	ENOG4108YZY	peptidylprolyl cis-trans isomerase
WP2S18C03_35360	ENOG4105VKU	nucleicacid-binding protein
WP2S18C03_35390	ENOG4105DNZ	Alpha Beta Hydrolase
WP2S18C03_35410	ENOG4105YP7	UPF0270 protein
WP2S18C03_35420	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
WP2S18C03_35450	ENOG4108UKZ	OsmC family
WP2S18C03_35460	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
WP2S18C03_35530	ENOG4105DD7	kinase (PfkB family
WP2S18C03_35540	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
WP2S18C03_35640	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
WP2S18C03_35660	ENOG4105C84	Histidine ammonia-lyase
WP2S18C03_35710	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
WP2S18C03_35720	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
WP2S18C03_35730	ENOG4105C2D	reductase
WP2S18C03_35780	ENOG4108ZQS	transposase
WP2S18C03_35800	ENOG4105F5W	AtP-binding protein
WP2S18C03_35810	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_35850	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WP2S18C03_35930	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
WP2S18C03_35940	ENOG4105BZU	Histidine kinase
WP2S18C03_35980	ENOG4105D0C	transport protein
WP2S18C03_35990	ENOG4108UT2	hemolysin iii
WP2S18C03_36000	ENOG4105DY8	decarboxylase
WP2S18C03_36010	ENOG4107835	probably involved in intracellular septation (By similarity)
WP2S18C03_36020	ENOG4105K9H	YciI-like protein
WP2S18C03_36030	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
WP2S18C03_36040	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
WP2S18C03_36050	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
WP2S18C03_36070	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
WP2S18C03_36080	ENOG4105C3F	Signal peptidase i
WP2S18C03_36090	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
WP2S18C03_36110	ENOG4105VQK	sigma E regulatory protein, MucB RseB
WP2S18C03_36120	ENOG41069PW	sigma-e factor negative regulatory protein
WP2S18C03_36130	ENOG4105EMN	RNA polymerase sigma factor
WP2S18C03_36140	ENOG4108IYU	L-aspartate oxidase
WP2S18C03_36170	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
WP2S18C03_36260	ENOG4105CJP	fad dependent oxidoreductase
WP2S18C03_36270	ENOG4105D2N	Aldolase
WP2S18C03_36280	ENOG4105BZA	Phosphoglycerate kinase
WP2S18C03_36290	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
WP2S18C03_36300	ENOG4105DKQ	ROK family
WP2S18C03_36310	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
WP2S18C03_36320	ENOG4105E09	nadh pyrophosphatase
WP2S18C03_36330	ENOG4105E09	nadh pyrophosphatase
WP2S18C03_36340	ENOG4105C26	Dehydrogenase
WP2S18C03_36350	ENOG4106MWK	domain protein
WP2S18C03_36360	ENOG4105EYW	Ion transport protein
WP2S18C03_36370	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_36390	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
WP2S18C03_36460	ENOG4105E09	nadh pyrophosphatase
WP2S18C03_36470	ENOG4107QWG	2-Nitropropane dioxygenase
WP2S18C03_36500	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
WP2S18C03_36520	ENOG4105BZU	Histidine kinase
WP2S18C03_36530	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_36550	ENOG4107QPK	)-transporter
WP2S18C03_36560	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
WP2S18C03_36580	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
WP2S18C03_36590	ENOG4105DWY	Agmatine deiminase
WP2S18C03_36610	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
WP2S18C03_36630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
WP2S18C03_36650	ENOG4108K5P	(LipO)protein
WP2S18C03_36660	ENOG4108UM1	dedA family
WP2S18C03_36670	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
WP2S18C03_36680	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
WP2S18C03_36690	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
WP2S18C03_36700	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
WP2S18C03_36710	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
WP2S18C03_36720	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
WP2S18C03_36730	ENOG4105CK7	Sodium proline symporter
WP2S18C03_36750	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
WP2S18C03_36760	ENOG4105CUY	Mechanosensitive ion channel
WP2S18C03_36780	ENOG4105XEP	YhcH YjgK YiaL family protein
WP2S18C03_36830	ENOG4107SQD	Transcriptional regulator, GntR family
WP2S18C03_36870	ENOG4105C5H	ABC transporter
WP2S18C03_36890	ENOG4105D6S	protein involved in catabolism of external DNA
WP2S18C03_36930	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
WP2S18C03_36950	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
WP2S18C03_36960	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
WP2S18C03_36970	ENOG4105DXN	mazG family
WP2S18C03_36980	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
WP2S18C03_36990	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
WP2S18C03_37000	ENOG4105BZU	Histidine kinase
WP2S18C03_37010	ENOG4108W15	Protein of unknown function (DUF1456)
WP2S18C03_37020	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
WP2S18C03_37030	ENOG4108RMU	ferritin dps family protein
WP2S18C03_37040	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
WP2S18C03_37050	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
WP2S18C03_37060	ENOG4105CMR	udp-glucose 4-epimerase
WP2S18C03_37070	ENOG41076MN	Phosphoesterase, PA-phosphatase related
WP2S18C03_37080	ENOG4105DFU	Cell wall formation (By similarity)
WP2S18C03_37090	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
WP2S18C03_37100	ENOG410630P	Transcriptional regulator
WP2S18C03_37110	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
WP2S18C03_37120	ENOG4105DA5	(ABC) transporter
WP2S18C03_37130	ENOG4105E3A	(ABC) transporter
WP2S18C03_37140	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
WP2S18C03_37150	ENOG4105CIZ	coA-substrate-specific enzyme activase
WP2S18C03_37190	ENOG4105CNN	ABC, transporter
WP2S18C03_37230	ENOG4108ETY	sodium dicarboxylate symporter
WP2S18C03_37250	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
WP2S18C03_37260	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
WP2S18C03_37270	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WP2S18C03_37280	ENOG4105DJ0	Poly(A) Polymerase
WP2S18C03_37290	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
WP2S18C03_37310	ENOG4105PW4	Sugar fermentation stimulation protein homolog
WP2S18C03_37330	ENOG4105CQ7	ATP-dependent helicase
WP2S18C03_37340	ENOG4105BZ4	penicillin-binding protein
WP2S18C03_37350	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
WP2S18C03_37360	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
WP2S18C03_37370	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
WP2S18C03_37390	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
WP2S18C03_37400	ENOG4105F0N	pyrophosphate phospho-hydrolase
WP2S18C03_37430	ENOG4108UUE	Transcriptional regulator
WP2S18C03_37500	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
WP2S18C03_37510	ENOG4105F5W	AtP-binding protein
WP2S18C03_37520	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_37530	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_37540	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
WP2S18C03_37550	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
WP2S18C03_37560	ENOG4105C11	sulfate adenylyltransferase), subunit 2
WP2S18C03_37570	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
WP2S18C03_37580	ENOG4107QX8	SPFH domain, Band 7 family protein
WP2S18C03_37590	ENOG4105G5H	Membrane
WP2S18C03_37600	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_37610	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
WP2S18C03_37620	ENOG4105DSB	aldose 1-epimerase
WP2S18C03_37640	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
WP2S18C03_37650	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
WP2S18C03_37670	ENOG4105E0X	reductase
WP2S18C03_37690	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
WP2S18C03_37710	ENOG4105EW9	transcriptional regulator AsnC family
WP2S18C03_37740	ENOG4108K4B	hydrolase
WP2S18C03_37770	ENOG4105C8J	)-transporter
WP2S18C03_37790	ENOG4105C8J	)-transporter
WP2S18C03_37800	ENOG4105UFD	tol-pal system protein YbgF
WP2S18C03_37810	ENOG4105KCK	Peptidoglycan-associated lipoprotein
WP2S18C03_37820	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
WP2S18C03_37840	ENOG4105M8F	Biopolymer transport protein exbD tolR
WP2S18C03_37850	ENOG4105E02	MotA TolQ exbB proton channel
WP2S18C03_37860	ENOG4107YD3	Thioesterase
WP2S18C03_37870	ENOG4105KJB	cyd operon protein YbgE
WP2S18C03_37890	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
WP2S18C03_37900	ENOG4105C4M	(Ubiquinol oxidase) subunit I
WP2S18C03_37910	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
WP2S18C03_37920	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
WP2S18C03_37930	ENOG4108N3W	hemolysin secretion protein
WP2S18C03_37940	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
WP2S18C03_37950	ENOG4105VJY	transcriptional regulator
WP2S18C03_37960	ENOG4105NNS	Autoinducer synthesis protein
WP2S18C03_37970	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
WP2S18C03_37980	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
WP2S18C03_38010	ENOG4107VXZ	Hydrolase
WP2S18C03_38020	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
WP2S18C03_38030	ENOG4105F1S	paraquat-inducible protein a
WP2S18C03_38040	ENOG4105DY2	Paraquat-inducible protein b
WP2S18C03_38050	ENOG4108Q2G	(LipO)protein
WP2S18C03_38060	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
WP2S18C03_38070	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
WP2S18C03_38090	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
WP2S18C03_38120	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
WP2S18C03_38150	ENOG4105E39	Enoyl-CoA hydratase
WP2S18C03_38160	ENOG4106WH9	Protein of unknown function (DUF2753)
WP2S18C03_38170	ENOG4105EQK	-acetyltransferase
WP2S18C03_38190	ENOG4107QSI	ABC, transporter
WP2S18C03_38210	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
WP2S18C03_38220	ENOG4105MYN	Zinc uptake regulation protein
WP2S18C03_38250	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
WP2S18C03_38260	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
WP2S18C03_38270	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
WP2S18C03_38280	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_38290	ENOG4107YB6	acetyltransferase, (GNAT) family
WP2S18C03_38320	ENOG4105C2N	RNA methyltransferase TrmH family group 3
WP2S18C03_38330	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
WP2S18C03_38340	ENOG4106TD9	Diguanylate cyclase
WP2S18C03_38350	ENOG4105UYK	outer membrane protein a
WP2S18C03_38380	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
WP2S18C03_38390	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
WP2S18C03_38400	ENOG4105CEN	a g-specific adenine glycosylase
WP2S18C03_38410	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
WP2S18C03_38450	ENOG4105R2J	Conserved Protein
WP2S18C03_38470	ENOG4105DR5	peptidase
WP2S18C03_38510	ENOG4105NXV	High-affinity zinc uptake system protein
WP2S18C03_38520	ENOG4105FDK	ABC transporter
WP2S18C03_38530	ENOG4105FAV	ABC, transporter
WP2S18C03_38540	ENOG4105ETT	transcriptional Regulator, LysR family
WP2S18C03_38550	ENOG4105DFI	Membrane
WP2S18C03_38560	ENOG4108RG0	uracil-dna glycosylase
WP2S18C03_38590	ENOG41082IR	Excinuclease ABC C subunit domain protein
WP2S18C03_38620	ENOG41087YS	Phage shock protein A
WP2S18C03_38630	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
WP2S18C03_38670	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP2S18C03_38680	ENOG4105C5Q	Transcriptional regulator
WP2S18C03_38700	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
WP2S18C03_38710	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
WP2S18C03_38750	ENOG4105DUX	Transporter
WP2S18C03_38790	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
WP2S18C03_38810	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WP2S18C03_38820	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
WP2S18C03_38830	ENOG4105DSW	Fusaric acid resistance protein
WP2S18C03_38840	ENOG4105Y49	secretion protein, HlyD family
WP2S18C03_38890	ENOG4105IPS	esterase
WP2S18C03_38900	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
WP2S18C03_38910	ENOG4108SX3	cytoplasmic protein
WP2S18C03_38920	ENOG41087AY	ADP-Ribose pyrophosphatase
WP2S18C03_38930	ENOG4105DFG	type I secretion outer membrane protein
WP2S18C03_38940	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
WP2S18C03_38950	ENOG4105D1S	lipid A biosynthesis
WP2S18C03_38960	ENOG4105CTS	PTS system mannitol-specific
WP2S18C03_38970	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
WP2S18C03_38980	ENOG4105E61	Mannitol repressor protein
WP2S18C03_39030	ENOG4108UPT	UPF0178 protein
WP2S18C03_39060	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
WP2S18C03_39070	ENOG4105D9N	nucleoside
WP2S18C03_39080	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_39120	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
WP2S18C03_39130	ENOG4105E4F	Isochorismate synthase
WP2S18C03_39140	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
WP2S18C03_39150	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
WP2S18C03_39160	ENOG4108IPT	Naphthoate synthase
WP2S18C03_39180	ENOG4105CEY	Amp-dependent synthetase and ligase
WP2S18C03_39210	ENOG4108MDY	Fimbrial
WP2S18C03_39230	ENOG4108FZ9	Chaperone
WP2S18C03_39240	ENOG4106PG1	outer membrane usher protein
WP2S18C03_39300	ENOG4107MM9	BNR Asp-box repeat-containing protein
WP2S18C03_39310	ENOG4108UB4	uncharacterized protein ygjQ
WP2S18C03_39320	ENOG4107R88	Chemotaxis protein (CheV)
WP2S18C03_39340	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
WP2S18C03_39370	ENOG4108UQY	Iron-storage protein
WP2S18C03_39380	ENOG4108Z5K	methylglyoxal synthase
WP2S18C03_39390	ENOG4108I6A	alcohol dehydrogenase
WP2S18C03_39410	ENOG4105DZW	Dipeptidase
WP2S18C03_39420	ENOG4105EMU	Dehydrogenase
WP2S18C03_39460	ENOG4105KT7	mgtC SapB transporter
WP2S18C03_39500	ENOG4105E0M	Sulfatase
WP2S18C03_39510	ENOG4108YXU	transcriptional regulator AsnC family
WP2S18C03_39530	ENOG4105CVG	Homoserine O-transsuccinylase
WP2S18C03_39540	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
WP2S18C03_39550	ENOG4108I62	cina-like protein
WP2S18C03_39570	ENOG410667J	hydrolase
WP2S18C03_39590	ENOG41090HJ	UPF0265 protein
WP2S18C03_39630	ENOG4105F5W	AtP-binding protein
WP2S18C03_39640	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_39700	ENOG4105VMP	Transcriptional regulator
WP2S18C03_39820	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_39830	ENOG4105F5W	AtP-binding protein
WP2S18C03_39860	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
WP2S18C03_39930	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_39940	ENOG4105F5W	AtP-binding protein
WP2S18C03_40010	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
WP2S18C03_40020	ENOG4105D3G	Pseudouridine synthase
WP2S18C03_40040	ENOG4108UW5	maltose o-acetyltransferase
WP2S18C03_40050	ENOG4105CG3	alpha amylase, catalytic region
WP2S18C03_40060	ENOG4105C5Y	PTS System
WP2S18C03_40070	ENOG4105D4X	repressor
WP2S18C03_40100	ENOG4105HDK	L-asparaginase
WP2S18C03_40120	ENOG4106W5V	Membrane
WP2S18C03_40130	ENOG41061WM	D-Alanyl-D-Alanine
WP2S18C03_40140	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
WP2S18C03_40150	ENOG4105CFH	Aspartokinase
WP2S18C03_40160	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
WP2S18C03_40170	ENOG4105Y3E	Modulates RecA activity (By similarity)
WP2S18C03_40180	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
WP2S18C03_40190	ENOG4107TH8	cina domain protein
WP2S18C03_40210	ENOG4105CEC	DNA methylase N-4 N-6
WP2S18C03_40240	ENOG4105DFP	Integrase
WP2S18C03_40250	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
WP2S18C03_40260	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
WP2S18C03_40270	ENOG4108NRW	Phospholipase, patatin family
WP2S18C03_40290	ENOG41067MG	lrgb family
WP2S18C03_40340	ENOG4105CMU	LysR family (Transcriptional regulator
WP2S18C03_40370	ENOG4108Z66	YbaK ebsC protein
WP2S18C03_40400	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
WP2S18C03_40420	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
WP2S18C03_40430	ENOG4105CAS	nag kinase
WP2S18C03_40450	ENOG4105CDH	Citrulline--aspartate ligase
WP2S18C03_40460	ENOG4105CH7	arginosuccinase
WP2S18C03_40490	ENOG4105DWD	nucleoside recognition domain protein
WP2S18C03_40500	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
WP2S18C03_40510	ENOG4107ZVW	dihydroneopterin aldolase
WP2S18C03_40520	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WP2S18C03_40530	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
WP2S18C03_40540	ENOG4105CKI	cobalamin synthesis protein
WP2S18C03_40560	ENOG4105BZU	Histidine kinase
WP2S18C03_40570	ENOG4107QIJ	Aconitate hydratase 2
WP2S18C03_40580	ENOG4105D78	K07001 NTE family protein
WP2S18C03_40590	ENOG4108N3W	hemolysin secretion protein
WP2S18C03_40610	ENOG4107QN2	dihydrolipoyl dehydrogenase
WP2S18C03_40620	ENOG4107QSN	dihydrolipoamide acetyltransferase
WP2S18C03_40630	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
WP2S18C03_40640	ENOG41073TP	transcriptional regulator
WP2S18C03_40670	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
WP2S18C03_40690	ENOG4107QHF	type ii secretion system protein e
WP2S18C03_40700	ENOG4105D7Q	type ii secretion system
WP2S18C03_40730	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
WP2S18C03_40740	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
WP2S18C03_40750	ENOG4105M6F	mutator MutT protein
WP2S18C03_40760	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
WP2S18C03_40780	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
WP2S18C03_40790	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
WP2S18C03_40800	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
WP2S18C03_40810	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
WP2S18C03_40820	ENOG4105DFU	Cell wall formation (By similarity)
WP2S18C03_40830	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
WP2S18C03_40840	ENOG4105CNI	cell division protein FtsW
WP2S18C03_40850	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
WP2S18C03_40860	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
WP2S18C03_40870	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
WP2S18C03_40880	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
WP2S18C03_40890	ENOG4105CJN	penicillin-binding protein
WP2S18C03_40900	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
WP2S18C03_40910	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
WP2S18C03_40920	ENOG4108V6E	Cell division protein mraZ
WP2S18C03_40930	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
WP2S18C03_40940	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
WP2S18C03_40950	ENOG41082RQ	UPF0102 protein
WP2S18C03_40960	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
WP2S18C03_40980	ENOG4105KB2	stringent starvation protein b
WP2S18C03_40990	ENOG4107MKT	Stringent starvation protein a
WP2S18C03_41000	ENOG4105EIX	cytochrome c1
WP2S18C03_41010	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
WP2S18C03_41020	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
WP2S18C03_41030	ENOG4108UJD	30S ribosomal protein S9
WP2S18C03_41040	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
WP2S18C03_41050	ENOG4105D6Z	AFG1 family ATPase
WP2S18C03_41070	ENOG4105C0H	protease
WP2S18C03_41080	ENOG4105C0H	protease
WP2S18C03_41140	ENOG41069H0	dihydroorotase EC 3.5.2.3
WP2S18C03_41170	ENOG4105EMD	TRANSCRIPTIONal
WP2S18C03_41180	ENOG41080Z8	PHOSPHOCARRIER protein
WP2S18C03_41190	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
WP2S18C03_41200	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
WP2S18C03_41210	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
WP2S18C03_41220	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
WP2S18C03_41230	ENOG4108IUZ	ABC transporter
WP2S18C03_41240	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
WP2S18C03_41270	ENOG4105C2X	Arabinose 5-phosphate isomerase
WP2S18C03_41280	ENOG4105DHJ	ABC, transporter
WP2S18C03_41290	ENOG4105CY3	ABC transporter, permease
WP2S18C03_41300	ENOG4107PE3	Mammalian cell entry related domain protein
WP2S18C03_41310	ENOG4105E3I	toluene tolerance
WP2S18C03_41330	ENOG4105VFK	BolA family
WP2S18C03_41340	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
WP2S18C03_41350	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
WP2S18C03_41360	ENOG4105N42	UPF0307 protein
WP2S18C03_41370	ENOG4108Z86	Glutamine amidotransferase
WP2S18C03_41390	ENOG4105EYW	Ion transport protein
WP2S18C03_41400	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
WP2S18C03_41410	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WP2S18C03_41430	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
WP2S18C03_41440	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
WP2S18C03_41450	ENOG4105XQ6	frataxin-like protein
WP2S18C03_41460	ENOG4106CJB	Phospholipase Carboxylesterase
WP2S18C03_41470	ENOG4107T0K	Adenylate cyclase
WP2S18C03_41490	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
WP2S18C03_41500	ENOG41076E6	Uroporphyrinogen-III Synthase
WP2S18C03_41510	ENOG4105ECF	c-methyltransferase
WP2S18C03_41530	ENOG4105KRS	Proteinase inhibitor
WP2S18C03_41540	ENOG4105CBT	Fructose-1,6-bisphosphatase
WP2S18C03_41580	ENOG4107SC7	Inner membrane transporter yjeM
WP2S18C03_41590	ENOG41061WM	D-Alanyl-D-Alanine
WP2S18C03_41610	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_41620	ENOG4105F5W	AtP-binding protein
WP2S18C03_41650	ENOG4105D4P	Coproporphyrinogen iii oxidase
WP2S18C03_41660	ENOG4105XCT	Protein of unknown function (DUF2489)
WP2S18C03_41670	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
WP2S18C03_41680	ENOG4106RE7	Cytochrome
WP2S18C03_41690	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
WP2S18C03_41700	ENOG4105SG3	Protein of unknown function (DUF1488)
WP2S18C03_41710	ENOG4105E2X	shikimate dehydrogenase
WP2S18C03_41720	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
WP2S18C03_41730	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
WP2S18C03_41750	ENOG4108WI1	Dna topoisomerase
WP2S18C03_41760	ENOG4108RPN	Protein smg homolog
WP2S18C03_41770	ENOG4105C79	DNA protecting protein DprA
WP2S18C03_41780	ENOG4108WZM	domain protein
WP2S18C03_41790	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
WP2S18C03_41800	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
WP2S18C03_41810	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
WP2S18C03_41820	ENOG4105C1A	potassium transporter peripheral membrane
WP2S18C03_41830	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
WP2S18C03_41840	ENOG4105CI3	gtp-binding protein typa
WP2S18C03_41850	ENOG4105C5F	glutamine synthetase
WP2S18C03_41870	ENOG4105CUX	Signal transduction histidine kinase
WP2S18C03_41880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
WP2S18C03_41890	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
WP2S18C03_41900	ENOG4105CGY	Dna recombination protein
WP2S18C03_41940	ENOG4108TFM	Kinase, PfkB family
WP2S18C03_41950	ENOG4107R11	Transcriptional regulator
WP2S18C03_41960	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
WP2S18C03_41970	ENOG4105C26	Dehydrogenase
WP2S18C03_41990	ENOG4108JCI	Transcriptional regulator
WP2S18C03_42000	ENOG4105C26	Dehydrogenase
WP2S18C03_42020	ENOG4105FR1	rard protein
WP2S18C03_42030	ENOG4108N3W	hemolysin secretion protein
WP2S18C03_42040	ENOG4105CUC	YeeE YedE family protein
WP2S18C03_42050	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
WP2S18C03_42080	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
WP2S18C03_42100	ENOG4105CEM	UPF0597 protein
WP2S18C03_42120	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
WP2S18C03_42130	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
WP2S18C03_42140	ENOG4108I6A	alcohol dehydrogenase
WP2S18C03_42150	ENOG4105CF7	AraC family transcriptional regulator
WP2S18C03_42160	ENOG4105QNF	Outer membrane lipoprotein
WP2S18C03_42210	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_42230	ENOG4105DUM	transcriptional regulator, lysR family
WP2S18C03_42240	ENOG4105DJ4	phosphatidylserine decarboxylase
WP2S18C03_42260	ENOG4105CXT	aspartate transcarbamylase
WP2S18C03_42270	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
WP2S18C03_42280	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
WP2S18C03_42290	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_42300	ENOG4105VNT	transposase (IS4 family) protein
WP2S18C03_42310	ENOG4105UYK	outer membrane protein a
WP2S18C03_42370	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
WP2S18C03_42380	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
WP2S18C03_42390	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_42400	ENOG4105F5W	AtP-binding protein
WP2S18C03_42410	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
WP2S18C03_42440	ENOG4105C7B	Threonine dehydratase
WP2S18C03_42450	ENOG4105C01	Dihydroxy-acid dehydratase
WP2S18C03_42460	ENOG4105CM2	brancheD-chain amino acid aminotransferase
WP2S18C03_42470	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
WP2S18C03_42490	ENOG4105C0P	Mg chelatase subunit ChlI
WP2S18C03_42500	ENOG4106HNH	Acyl-transferase
WP2S18C03_42510	ENOG4106HNH	Acyl-transferase
WP2S18C03_42520	ENOG4105EWC	Purine nucleoside phosphorylase
WP2S18C03_42540	ENOG4108RWI	nicotinamidase
WP2S18C03_42550	ENOG4107RH7	Nicotinate phosphoribosyltransferase
WP2S18C03_42560	ENOG4108Z33	Thiol disulfide Interchange Protein
WP2S18C03_42570	ENOG4105E27	serine threonine protein kinase
WP2S18C03_42590	ENOG4105PC1	Conserved Protein
WP2S18C03_42610	ENOG4108Z6Z	Transcriptional regulator
WP2S18C03_42630	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
WP2S18C03_42640	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
WP2S18C03_42650	ENOG4105DSJ	YicC domain protein
WP2S18C03_42660	ENOG4105CC0	LysR family Transcriptional regulator
WP2S18C03_42690	ENOG4105CR8	Transcriptional regulator
WP2S18C03_42780	ENOG4105DHU	Bile acid
WP2S18C03_42790	ENOG4105E5D	amino acid
WP2S18C03_42800	ENOG4108Y51	tRNA-binding protein
WP2S18C03_42810	ENOG4105E5D	amino acid
WP2S18C03_42820	ENOG4105FK9	beta-D-galactosidase beta subunit
WP2S18C03_42830	ENOG4105CNT	hydrolase family 2
WP2S18C03_42840	ENOG4105CQ4	Transcriptional regulator
WP2S18C03_42850	ENOG4108Z0R	Transferase
WP2S18C03_42860	ENOG4105C2M	dna polymerase I
WP2S18C03_42870	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
WP2S18C03_42890	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
WP2S18C03_42910	ENOG4105D7W	serine acetyltransferase
WP2S18C03_42930	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
WP2S18C03_42940	ENOG4105E0F	Histidine kinase
WP2S18C03_42950	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
WP2S18C03_42960	ENOG4107R73	Mate efflux family protein
WP2S18C03_42990	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
WP2S18C03_43000	ENOG4105E55	glycerol-3-phosphate acyltransferase
WP2S18C03_43010	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
WP2S18C03_43020	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
WP2S18C03_43030	ENOG4105X6C	Flagellar basal body-associated protein FliL
WP2S18C03_43070	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
WP2S18C03_43080	ENOG4105DIQ	Transcriptional regulator
WP2S18C03_43090	ENOG4106ETB	IIa component
WP2S18C03_43120	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
WP2S18C03_43130	ENOG4105XA0	heptosyltransferase ii
WP2S18C03_43140	ENOG4106WTF	Glycosyl transferase, family 2
WP2S18C03_43150	ENOG4105M5K	heptosyltransferase
WP2S18C03_43160	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
WP2S18C03_43170	ENOG4108MJ5	VirK protein
WP2S18C03_43180	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
WP2S18C03_43200	ENOG4105W0E	50S ribosomal protein L33
WP2S18C03_43210	ENOG4105KDC	50s ribosomal protein l28
WP2S18C03_43220	ENOG4105W5Q	DNA repair protein (RadC
WP2S18C03_43230	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
WP2S18C03_43240	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
WP2S18C03_43250	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
WP2S18C03_43260	ENOG4105D64	Mechanosensitive ion channel
WP2S18C03_43270	ENOG4107QP8	phosphohexose isomerase
WP2S18C03_43280	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
WP2S18C03_43290	ENOG4105EMY	transcriptional regulator
WP2S18C03_43320	ENOG4105CD5	CoA-binding domain protein
WP2S18C03_43360	ENOG4108RR8	protoporphyrinogen oxidase
WP2S18C03_43370	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
WP2S18C03_43380	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
WP2S18C03_43390	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
WP2S18C03_43400	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
WP2S18C03_43410	ENOG4105D70	Integrase catalytic subunit
WP2S18C03_43420	ENOG4105F5W	AtP-binding protein
WP2S18C03_43430	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
WP2S18C03_43440	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
WP2S18C03_43450	ENOG4105CHU	acetyl-coa acetyltransferase
WP2S18C03_43470	ENOG4105E0F	Histidine kinase
WP2S18C03_43500	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
WP2S18C03_43510	ENOG4105M4H	endoribonuclease L-psp
WP2S18C03_43520	ENOG4108ZG0	Ompa motb domain protein
WP2S18C03_43530	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_43540	ENOG4108R3E	Dna-3-methyladenine glycosylase i
WP2S18C03_43550	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
WP2S18C03_43560	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
WP2S18C03_43600	ENOG4105C8Q	Methyl-accepting chemotaxis
WP2S18C03_43620	ENOG4105ETE	Transcriptional regulator (LacI family
WP2S18C03_43630	ENOG4105CP9	extracellular ligand-binding receptor
WP2S18C03_43640	ENOG4105C32	Amino acid ABC transporter (Permease)
WP2S18C03_43650	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
WP2S18C03_43660	ENOG4105C0Z	ABC transporter
WP2S18C03_43670	ENOG4108IV0	ABC, transporter
WP2S18C03_43680	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
WP2S18C03_43710	ENOG4105W0Z	cytoplasmic protein
WP2S18C03_43720	ENOG4105BZU	Histidine kinase
WP2S18C03_43730	ENOG4107QK7	reductase
WP2S18C03_43740	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
WP2S18C03_43760	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
WP2S18C03_43780	ENOG4105C1J	atp-dependent rna helicase
WP2S18C03_43790	ENOG4105C9X	ppx gppa phosphatase
WP2S18C03_43810	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
WP2S18C03_43830	ENOG4105BZU	Histidine kinase
WP2S18C03_43840	ENOG4105DGW	oligopeptidase A
WP2S18C03_43850	ENOG4105E03	chitinase
WP2S18C03_43860	ENOG4105D52	delta-aminolevulinic acid dehydratase
WP2S18C03_43870	ENOG4105F8V	Hydrolase, tatD family
WP2S18C03_43880	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
WP2S18C03_43890	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
WP2S18C03_43900	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
WP2S18C03_43910	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
WP2S18C03_43920	ENOG4105JC1	sterol-binding domain protein
WP2S18C03_43930	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
WP2S18C03_43940	ENOG4105DZC	cytosine deaminase
WP2S18C03_43950	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
WP2S18C03_43980	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
WP2S18C03_44010	ENOG410822N	TonB family
WP2S18C03_44020	ENOG4109015	Biopolymer transport protein exbD tolR
WP2S18C03_44070	ENOG4105VJY	transcriptional regulator
WP2S18C03_44080	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
WP2S18C03_44090	ENOG410804X	Transcriptional regulator
WP2S18C03_44100	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
WP2S18C03_44110	ENOG4105EB3	Histidine kinase
WP2S18C03_44140	ENOG4105CT7	inner membrane cred family protein
WP2S18C03_44150	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
WP2S18C03_44160	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
WP2S18C03_44170	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
WP2S18C03_44180	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
WP2S18C03_44190	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
WP2S18C03_44200	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WP2S18C03_44210	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WP2S18C03_44220	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
WP2S18C03_44230	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
WP2S18C03_44250	ENOG4105FA0	parb-like partition protein
WP2S18C03_44260	ENOG4107QJE	Chromosome Partitioning Protein
WP2S18C03_44270	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
WP2S18C03_44280	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
WP2S18C03_44290	ENOG4105QTB	Flavodoxin
WP2S18C03_44310	ENOG4105CAF	HipA N-terminal domain protein
WP2S18C03_44480	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WP2S18C03_44490	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
WP2S18C03_44500	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
WP2S18C03_44510	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
WP2S18C03_44520	ENOG4105VG0	50S ribosomal protein l34
WP2S18C03_44530	ENOG4105CDA	abc transporter atp-binding protein
WP2S18C03_44540	ENOG4105E5Q	amino acid AbC transporter
WP2S18C03_44550	ENOG4105EAB	amino acid AbC transporter
WP2S18C03_P10130	ENOG410600T	transposase
WP2S18C03_P10140	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
WP2S18C03_P10170	ENOG4105VXN	addiction module toxin, RelE StbE family
WP2S18C03_P10180	ENOG4108C33	Resolvase
WP2S18C03_P10210	ENOG4108C33	Resolvase
WP2S18C03_P10240	ENOG4105E0X	reductase
WP2S18C03_P10270	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
WP2S18C03_P10310	ENOG410600T	transposase
WP2S18C03_P10360	ENOG4105DIJ	Phosphoethanolamine transferase
WP2S18C03_P10420	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
WP2S18C03_P10430	ENOG4108JUA	Transcriptional regulator
WP2S18C03_P10560	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
WP2S18C03_P10650	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
WP2S18C03_P10660	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
WP2S18C03_P10730	ENOG4105C9A	Phoh family
WP2S18C03_P10750	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
WP2S18C03_P20040	ENOG4105VXN	addiction module toxin, RelE StbE family
WP2S18C03_P20050	ENOG4108C33	Resolvase
WP2S18C03_P20070	ENOG4107W31	Pentapeptide repeat protein
WP2S18C03_P20120	ENOG4108BUD	transposase
WP2S18C03_P20180	ENOG4105C26	Dehydrogenase
WP2S18C03_P30150	ENOG4105DIJ	Phosphoethanolamine transferase