locus-tag	class	description
WP3W19E03_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WP3W19E03_00020	COG0592	DNA-directed DNA polymerase activity
WP3W19E03_00040	COG0187	DNA topoisomerase II activity
WP3W19E03_00060	COG2378	regulation of single-species biofilm formation
WP3W19E03_00080	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WP3W19E03_00090	COG0071	Belongs to the small heat shock protein (HSP20) family
WP3W19E03_00100	COG0071	Belongs to the small heat shock protein (HSP20) family
WP3W19E03_00110	COG3977	Valine--pyruvate aminotransferase
WP3W19E03_00140	COG2814	Major facilitator Superfamily
WP3W19E03_00150	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_00160	COG2205	protein histidine kinase activity
WP3W19E03_00200	COG1733	regulation of RNA biosynthetic process
WP3W19E03_00210	COG0604	alcohol dehydrogenase
WP3W19E03_00230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP3W19E03_00240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_00240	COG4191	Histidine kinase
WP3W19E03_00250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP3W19E03_00260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_00270	COG1309	transcriptional regulator
WP3W19E03_00290	COG0469	pyruvate kinase activity
WP3W19E03_00300	COG2271	Major facilitator Superfamily
WP3W19E03_00350	COG0561	phosphatase activity
WP3W19E03_00360	COG2267	carboxylic ester hydrolase activity
WP3W19E03_00370	COG0110	maltose O-acetyltransferase activity
WP3W19E03_00380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP3W19E03_00400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP3W19E03_00410	COG1758	RNA polymerase activity
WP3W19E03_00420	COG0194	GDP metabolic process
WP3W19E03_00430	COG0859	PFAM glycosyl transferase family 9
WP3W19E03_00440	COG3642	lipopolysaccharide core region biosynthetic process
WP3W19E03_00520	COG0589	response to stress
WP3W19E03_00530	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP3W19E03_00540	COG1528	Iron-storage protein
WP3W19E03_00550	COG2081	HI0933 family
WP3W19E03_00560	COG3275	phosphorelay sensor kinase activity
WP3W19E03_00570	COG3279	Response regulator of the LytR AlgR family
WP3W19E03_00580	COG2223	nitrite transmembrane transporter activity
WP3W19E03_00590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WP3W19E03_00600	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WP3W19E03_00630	COG0583	DNA-binding transcription factor activity
WP3W19E03_00680	COG3012	SEC-C Motif Domain Protein
WP3W19E03_00680	COG3318	Belongs to the UPF0149 family
WP3W19E03_00850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP3W19E03_00870	COG2003	Belongs to the UPF0758 family
WP3W19E03_00970	COG3311	Transcriptional regulator
WP3W19E03_00990	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP3W19E03_01000	COG2801	Transposase and inactivated derivatives
WP3W19E03_01030	COG0582	viral genome integration into host DNA
WP3W19E03_01050	COG0045	succinate-CoA ligase (ADP-forming) activity
WP3W19E03_01050	COG1042	CoA-binding domain protein
WP3W19E03_01050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP3W19E03_01090	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WP3W19E03_01100	COG0166	Belongs to the GPI family
WP3W19E03_01110	COG0668	transmembrane transport
WP3W19E03_01120	COG1309	transcriptional regulator
WP3W19E03_01130	COG0756	dUTP diphosphatase activity
WP3W19E03_01140	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WP3W19E03_01150	COG2003	Belongs to the UPF0758 family
WP3W19E03_01160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WP3W19E03_01170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WP3W19E03_01190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WP3W19E03_01200	COG2990	Protein conserved in bacteria
WP3W19E03_01210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WP3W19E03_01220	COG0859	PFAM glycosyl transferase family 9
WP3W19E03_01230	COG0463	Glycosyl transferase, family 2
WP3W19E03_01240	COG0859	PFAM glycosyl transferase family 9
WP3W19E03_01250	COG1519	Transferase
WP3W19E03_01280	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_01290	COG1609	Transcriptional regulator
WP3W19E03_01300	COG0604	alcohol dehydrogenase
WP3W19E03_01350	COG3161	chorismate lyase activity
WP3W19E03_01360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WP3W19E03_01370	COG2937	Belongs to the GPAT DAPAT family
WP3W19E03_01380	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WP3W19E03_01410	COG0534	Mate efflux family protein
WP3W19E03_01420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WP3W19E03_01430	COG2205	protein histidine kinase activity
WP3W19E03_01440	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_01460	COG1045	serine acetyltransferase
WP3W19E03_01480	COG3074	FtsZ-dependent cytokinesis
WP3W19E03_01490	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WP3W19E03_01500	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP3W19E03_01500	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP3W19E03_01510	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WP3W19E03_01520	COG1609	Transcriptional regulator
WP3W19E03_01530	COG3250	beta-galactosidase activity
WP3W19E03_01540	COG2731	YhcH YjgK YiaL family protein
WP3W19E03_01550	COG0531	amino acid
WP3W19E03_01560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP3W19E03_01570	COG0531	amino acid
WP3W19E03_01580	COG0385	Bile acid
WP3W19E03_01630	COG0583	DNA-binding transcription factor activity
WP3W19E03_01640	COG2814	Major facilitator Superfamily
WP3W19E03_01660	COG1538	Outer membrane efflux protein
WP3W19E03_01670	COG1309	transcriptional regulator
WP3W19E03_01680	COG1561	YicC-like family, N-terminal region
WP3W19E03_01690	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
WP3W19E03_01700	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WP3W19E03_01730	COG5001	Diguanylate cyclase
WP3W19E03_01730	COG4251	negative regulation of phosphorylation
WP3W19E03_01730	COG3706	GGDEF domain
WP3W19E03_01730	COG2203	Gaf domain
WP3W19E03_01740	COG3084	Protein conserved in bacteria
WP3W19E03_01760	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WP3W19E03_01770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP3W19E03_01790	COG1335	isochorismatase
WP3W19E03_01810	COG1683	Conserved Protein
WP3W19E03_01820	COG0204	Acyl-transferase
WP3W19E03_01830	COG0204	Acyl-transferase
WP3W19E03_01840	COG0606	chelatase, subunit chli
WP3W19E03_01860	COG3978	acetolactate synthase activity
WP3W19E03_01880	COG0129	dihydroxy-acid dehydratase activity
WP3W19E03_01910	COG2391	methyltransferase activity
WP3W19E03_01920	COG0840	transmembrane signaling receptor activity
WP3W19E03_01930	COG2962	Rard protein
WP3W19E03_01950	COG1012	belongs to the aldehyde dehydrogenase family
WP3W19E03_01960	COG1396	sequence-specific DNA binding
WP3W19E03_01990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP3W19E03_01990	COG0519	Catalyzes the synthesis of GMP from XMP
WP3W19E03_02000	COG0583	DNA-binding transcription factor activity
WP3W19E03_02010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_02060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WP3W19E03_02070	COG2204	response regulator
WP3W19E03_02100	COG0174	glutamine synthetase
WP3W19E03_02120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP3W19E03_02130	COG0569	domain protein
WP3W19E03_02140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP3W19E03_02140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP3W19E03_02150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WP3W19E03_02160	COG0242	peptide deformylase activity
WP3W19E03_02170	COG1652	LysM domain
WP3W19E03_02180	COG0758	DNA mediated transformation
WP3W19E03_02190	COG2922	Belongs to the Smg family
WP3W19E03_02200	COG0551	DNA topoisomerase type I activity
WP3W19E03_02220	COG0009	L-threonylcarbamoyladenylate synthase
WP3W19E03_02230	COG0408	coproporphyrinogen oxidase activity
WP3W19E03_02240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WP3W19E03_02260	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WP3W19E03_02280	COG3078	GTPase activator activity
WP3W19E03_02300	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP3W19E03_02360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP3W19E03_02370	COG1288	antiporter activity
WP3W19E03_02380	COG1438	arginine binding
WP3W19E03_02390	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
WP3W19E03_02400	COG0540	Belongs to the ATCase OTCase family
WP3W19E03_02440	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
WP3W19E03_02480	COG3040	lipid binding
WP3W19E03_02490	COG2207	Transcriptional regulator
WP3W19E03_02500	COG1979	alcohol dehydrogenase
WP3W19E03_02510	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WP3W19E03_02520	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WP3W19E03_02530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_02540	COG2964	Protein conserved in bacteria
WP3W19E03_02550	COG3681	Belongs to the UPF0597 family
WP3W19E03_02570	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP3W19E03_02580	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP3W19E03_02590	COG0564	pseudouridine synthase activity
WP3W19E03_02610	COG0542	response to heat
WP3W19E03_02620	COG2502	aspartate--ammonia ligase
WP3W19E03_02630	COG1522	sequence-specific DNA binding
WP3W19E03_02650	COG5413	integral membrane protein
WP3W19E03_02660	COG0517	IMP dehydrogenase activity
WP3W19E03_02660	COG0516	GMP reductase activity
WP3W19E03_02670	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_02700	COG2205	protein histidine kinase activity
WP3W19E03_02720	COG2204	response regulator
WP3W19E03_02760	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
WP3W19E03_02790	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_02800	COG2205	protein histidine kinase activity
WP3W19E03_02820	COG0243	molybdopterin cofactor binding
WP3W19E03_02830	COG3005	denitrification pathway
WP3W19E03_02840	COG4191	Histidine kinase
WP3W19E03_02840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_02870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP3W19E03_02880	COG0569	domain protein
WP3W19E03_02890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WP3W19E03_02920	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP3W19E03_02940	COG0250	Participates in transcription elongation, termination and antitermination
WP3W19E03_02950	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WP3W19E03_02960	COG0081	regulation of translation
WP3W19E03_02970	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WP3W19E03_02980	COG0222	ribosome binding
WP3W19E03_02990	COG0085	RNA polymerase activity
WP3W19E03_03000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WP3W19E03_03010	COG2964	Protein conserved in bacteria
WP3W19E03_03030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP3W19E03_03040	COG2923	Belongs to the DsrF TusC family
WP3W19E03_03050	COG2168	tRNA wobble position uridine thiolation
WP3W19E03_03060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WP3W19E03_03070	COG0049	tRNA binding
WP3W19E03_03080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WP3W19E03_03090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP3W19E03_03100	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP3W19E03_03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP3W19E03_03110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP3W19E03_03140	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WP3W19E03_03150	COG0038	chloride channel
WP3W19E03_03170	COG0316	Belongs to the HesB IscA family
WP3W19E03_03180	COG1757	Na H antiporter
WP3W19E03_03210	COG0297	glycogen (starch) synthase activity
WP3W19E03_03220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP3W19E03_03230	COG2813	Specifically methylates the guanine in position
WP3W19E03_03240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP3W19E03_03260	COG1392	Phosphate transport regulator
WP3W19E03_03270	COG0306	phosphate transporter
WP3W19E03_03280	COG0460	homoserine dehydrogenase
WP3W19E03_03280	COG0527	aspartate kinase activity
WP3W19E03_03290	COG0626	cystathionine gamma-synthase activity
WP3W19E03_03310	COG0814	amino acid
WP3W19E03_03320	COG1218	3'(2'),5'-bisphosphate nucleotidase
WP3W19E03_03330	COG0494	nUDIX hydrolase
WP3W19E03_03340	COG1011	Hydrolase
WP3W19E03_03370	COG0110	maltose O-acetyltransferase activity
WP3W19E03_03380	COG3174	membrane
WP3W19E03_03390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WP3W19E03_03410	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WP3W19E03_03420	COG4208	sulfate ABC transporter
WP3W19E03_03430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WP3W19E03_03440	COG0583	DNA-binding transcription factor activity
WP3W19E03_03450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP3W19E03_03460	COG0765	amino acid transport
WP3W19E03_03480	COG1126	abc transporter atp-binding protein
WP3W19E03_03490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_03500	COG3397	chitin binding
WP3W19E03_03510	COG0840	transmembrane signaling receptor activity
WP3W19E03_03540	COG0726	polysaccharide deacetylase
WP3W19E03_03540	COG1649	PFAM Uncharacterised BCR, COG1649
WP3W19E03_03550	COG1215	transferase activity, transferring glycosyl groups
WP3W19E03_03610	COG1328	CTP reductase activity
WP3W19E03_03620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP3W19E03_03650	COG1448	Aminotransferase
WP3W19E03_03700	COG5433	transposase activity
WP3W19E03_03750	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_03800	COG3112	Uncharacterised protein family (UPF0231)
WP3W19E03_03810	COG3835	regulator
WP3W19E03_03820	COG2610	gluconate transmembrane transporter activity
WP3W19E03_03830	COG1929	Belongs to the glycerate kinase type-1 family
WP3W19E03_03870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP3W19E03_03890	COG1872	DUF167
WP3W19E03_03900	COG0762	integral membrane protein
WP3W19E03_03910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WP3W19E03_03920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WP3W19E03_03950	COG3022	response to hydroperoxide
WP3W19E03_03990	COG0347	Belongs to the P(II) protein family
WP3W19E03_04000	COG1840	ABC-type Fe3 transport system, periplasmic component
WP3W19E03_04020	COG3842	ATPase activity
WP3W19E03_04030	COG2837	iron assimilation
WP3W19E03_04040	COG1438	arginine binding
WP3W19E03_04050	COG1126	abc transporter atp-binding protein
WP3W19E03_04060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_04070	COG4215	(ABC) transporter
WP3W19E03_04080	COG4160	amino acid transport
WP3W19E03_04090	COG0039	L-malate dehydrogenase activity
WP3W19E03_04100	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WP3W19E03_04110	COG1017	nitric oxide dioxygenase activity
WP3W19E03_04110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP3W19E03_04130	COG4536	flavin adenine dinucleotide binding
WP3W19E03_04140	COG4137	Cytochrome C assembly protein
WP3W19E03_04160	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WP3W19E03_04170	COG0228	four-way junction DNA binding
WP3W19E03_04180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WP3W19E03_04190	COG0336	Belongs to the RNA methyltransferase TrmD family
WP3W19E03_04200	COG0335	large ribosomal subunit rRNA binding
WP3W19E03_04220	COG3066	DNA modification
WP3W19E03_04230	COG1051	belongs to the nudix hydrolase family
WP3W19E03_04250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WP3W19E03_04260	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WP3W19E03_04270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP3W19E03_04290	COG0583	DNA-binding transcription factor activity
WP3W19E03_04300	COG0640	Transcriptional regulator
WP3W19E03_04310	COG0268	Binds directly to 16S ribosomal RNA
WP3W19E03_04320	COG0728	peptidoglycan biosynthetic process
WP3W19E03_04330	COG0196	riboflavin kinase activity
WP3W19E03_04340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WP3W19E03_04350	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WP3W19E03_04360	COG1047	Peptidyl-prolyl cis-trans
WP3W19E03_04370	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WP3W19E03_04430	COG5433	transposase activity
WP3W19E03_04480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WP3W19E03_04480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP3W19E03_04510	COG1854	S-ribosylhomocysteine lyase activity
WP3W19E03_04540	COG0084	hydrolase, TatD family'
WP3W19E03_04550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP3W19E03_04570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WP3W19E03_04580	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WP3W19E03_04590	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WP3W19E03_04610	COG5002	protein histidine kinase activity
WP3W19E03_04610	COG5001	Diguanylate cyclase
WP3W19E03_04610	COG3447	MASE1 domain protein
WP3W19E03_04630	COG0560	Phosphoserine phosphatase
WP3W19E03_04660	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WP3W19E03_04690	COG0776	regulation of translation
WP3W19E03_04710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP3W19E03_04720	COG1914	H( )-stimulated, divalent metal cation uptake system
WP3W19E03_04730	COG0360	Binds together with S18 to 16S ribosomal RNA
WP3W19E03_04740	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WP3W19E03_04750	COG0359	binds to the 23S rRNA
WP3W19E03_04760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP3W19E03_04800	COG1064	alcohol dehydrogenase
WP3W19E03_04810	COG1238	metal cluster binding
WP3W19E03_04820	COG0612	Peptidase, M16
WP3W19E03_04830	COG2918	glutathione biosynthetic process
WP3W19E03_04850	COG1022	Amp-dependent synthetase and ligase
WP3W19E03_04870	COG0456	acetyltransferase
WP3W19E03_04920	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WP3W19E03_04960	COG0477	Major facilitator Superfamily
WP3W19E03_04970	COG0583	DNA-binding transcription factor activity
WP3W19E03_04980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP3W19E03_04990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP3W19E03_05010	COG0673	inositol 2-dehydrogenase activity
WP3W19E03_05030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WP3W19E03_05040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP3W19E03_05050	COG3036	rescue of stalled ribosome
WP3W19E03_05070	COG0138	bifunctional purine biosynthesis protein purh
WP3W19E03_05080	COG0151	Belongs to the GarS family
WP3W19E03_05110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WP3W19E03_05120	COG0358	DNA primase activity
WP3W19E03_05130	COG1610	YqeY-like protein
WP3W19E03_05140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WP3W19E03_05150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WP3W19E03_05160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP3W19E03_05170	COG1027	Aspartate ammonia-lyase
WP3W19E03_05180	COG3030	protein affecting phage T7 exclusion by the F plasmid
WP3W19E03_05190	COG0534	Mate efflux family protein
WP3W19E03_05200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WP3W19E03_05210	COG0459	protein refolding
WP3W19E03_05310	COG3714	YhhN family
WP3W19E03_05360	COG1301	dicarboxylic acid transport
WP3W19E03_05380	COG2095	MarC family integral membrane protein
WP3W19E03_05420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP3W19E03_05440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP3W19E03_05470	COG1770	oligopeptidase
WP3W19E03_05500	COG4221	oxidoreductase activity
WP3W19E03_05510	COG0583	DNA-binding transcription factor activity
WP3W19E03_05520	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP3W19E03_05570	COG0742	ribosomal rna small subunit methyltransferase
WP3W19E03_05580	COG0552	protein localization to endoplasmic reticulum
WP3W19E03_05590	COG2884	Cell division ATP-binding protein ftsE
WP3W19E03_05600	COG2177	Part of the ABC transporter FtsEX involved in
WP3W19E03_05620	COG0288	reversible hydration of carbon dioxide
WP3W19E03_05630	COG2188	Transcriptional regulator
WP3W19E03_05640	COG1228	amidohydrolase
WP3W19E03_05650	COG0010	Belongs to the arginase family
WP3W19E03_05660	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WP3W19E03_05670	COG2986	histidine ammonia-lyase
WP3W19E03_05680	COG0387	Pfam Sodium calcium exchanger
WP3W19E03_05690	COG2200	EAL domain
WP3W19E03_05700	COG2200	EAL domain
WP3W19E03_05700	COG2199	diguanylate cyclase activity
WP3W19E03_05790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP3W19E03_05800	COG1459	type II secretion system
WP3W19E03_05840	COG4968	Prepilin-type N-terminal cleavage methylation domain
WP3W19E03_05890	COG1077	Cell shape determining protein MreB Mrl
WP3W19E03_05900	COG1792	Involved in formation and maintenance of cell shape
WP3W19E03_05910	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WP3W19E03_05920	COG0424	maF-like protein
WP3W19E03_05930	COG1530	ribonuclease E activity
WP3W19E03_05940	COG3164	Protein of unknown function
WP3W19E03_05960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP3W19E03_05970	COG0312	modulator of DNA gyrase
WP3W19E03_06010	COG0477	Major facilitator Superfamily
WP3W19E03_06100	COG0189	ligase activity
WP3W19E03_06110	COG0642	Histidine kinase
WP3W19E03_06120	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_06150	COG0789	Transcriptional regulator
WP3W19E03_06160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WP3W19E03_06170	COG0352	thiamine-phosphate diphosphorylase activity
WP3W19E03_06180	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP3W19E03_06200	COG2022	thiamine diphosphate biosynthetic process
WP3W19E03_06210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP3W19E03_06220	COG5433	transposase activity
WP3W19E03_06300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WP3W19E03_06340	COG0583	DNA-binding transcription factor activity
WP3W19E03_06350	COG1380	Effector of murein hydrolase LrgA
WP3W19E03_06360	COG1346	cytolysis
WP3W19E03_06380	COG4667	esterase of the alpha-beta hydrolase superfamily
WP3W19E03_06390	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WP3W19E03_06400	COG0582	viral genome integration into host DNA
WP3W19E03_06460	COG3706	GGDEF domain
WP3W19E03_06480	COG0840	transmembrane signaling receptor activity
WP3W19E03_06490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_06510	COG4467	Involved in initiation control of chromosome replication
WP3W19E03_06520	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP3W19E03_06610	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP3W19E03_06740	COG2003	Belongs to the UPF0758 family
WP3W19E03_06850	COG5377	YqaJ viral recombinase family
WP3W19E03_06870	COG1546	Belongs to the CinA family
WP3W19E03_06880	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WP3W19E03_06900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP3W19E03_06920	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WP3W19E03_06930	COG1686	Belongs to the peptidase S11 family
WP3W19E03_06940	COG0586	Pfam SNARE associated Golgi protein
WP3W19E03_06950	COG1253	flavin adenine dinucleotide binding
WP3W19E03_06960	COG0252	asparaginase activity
WP3W19E03_07000	COG1263	PTS System
WP3W19E03_07000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP3W19E03_07010	COG0366	Alpha amylase catalytic
WP3W19E03_07020	COG0110	maltose O-acetyltransferase activity
WP3W19E03_07040	COG0564	pseudouridine synthase activity
WP3W19E03_07050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP3W19E03_07070	COG1484	DNA-dependent DNA replication
WP3W19E03_07080	COG4584	PFAM Integrase catalytic
WP3W19E03_07120	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WP3W19E03_07130	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WP3W19E03_07140	COG1178	ABC-type Fe3 transport system permease component
WP3W19E03_07180	COG0066	3-isopropylmalate dehydratase activity
WP3W19E03_07190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WP3W19E03_07200	COG0473	3-isopropylmalate dehydrogenase activity
WP3W19E03_07210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP3W19E03_07260	COG0028	Belongs to the TPP enzyme family
WP3W19E03_07280	COG0440	acetolactate synthase activity
WP3W19E03_07290	COG3385	transposase activity
WP3W19E03_07380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WP3W19E03_07390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP3W19E03_07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_07470	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_07480	COG3104	oligopeptide transport
WP3W19E03_07490	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WP3W19E03_07500	COG1555	photosystem II stabilization
WP3W19E03_07510	COG0857	belongs to the CobB CobQ family
WP3W19E03_07510	COG0280	phosphate acetyltransferase
WP3W19E03_07520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP3W19E03_07540	COG3013	Belongs to the UPF0304 family
WP3W19E03_07550	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP3W19E03_07560	COG2716	regulation of RNA biosynthetic process
WP3W19E03_07570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP3W19E03_07580	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WP3W19E03_07590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WP3W19E03_07660	COG0784	Response regulator, receiver
WP3W19E03_07660	COG5002	protein histidine kinase activity
WP3W19E03_07660	COG2198	Histidine kinase
WP3W19E03_07690	COG0784	Response regulator, receiver
WP3W19E03_07690	COG2205	protein histidine kinase activity
WP3W19E03_07730	COG1464	Belongs to the NlpA lipoprotein family
WP3W19E03_07740	COG2011	ABC-type metal ion transport system permease component
WP3W19E03_07750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP3W19E03_07790	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WP3W19E03_07790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WP3W19E03_07800	COG0802	atpase or kinase
WP3W19E03_07820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WP3W19E03_07830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WP3W19E03_07840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WP3W19E03_07850	COG1923	regulation of RNA biosynthetic process
WP3W19E03_07860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WP3W19E03_07870	COG0330	HflC and HflK could
WP3W19E03_07880	COG0330	HflC and HflK could
WP3W19E03_07890	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WP3W19E03_07900	COG0142	geranyltranstransferase activity
WP3W19E03_07910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WP3W19E03_07920	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WP3W19E03_07930	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WP3W19E03_07950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP3W19E03_07970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WP3W19E03_07980	COG2967	ApaG domain
WP3W19E03_07990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WP3W19E03_08000	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WP3W19E03_08010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP3W19E03_08020	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WP3W19E03_08030	COG3178	'Phosphotransferase
WP3W19E03_08040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WP3W19E03_08050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP3W19E03_08060	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP3W19E03_08080	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WP3W19E03_08120	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WP3W19E03_08150	COG4628	conserved protein (DUF2132)
WP3W19E03_08160	COG0688	phosphatidylethanolamine metabolic process
WP3W19E03_08180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WP3W19E03_08190	COG1278	Cold shock
WP3W19E03_08210	COG0840	transmembrane signaling receptor activity
WP3W19E03_08220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP3W19E03_08240	COG2252	PERMEase
WP3W19E03_08260	COG0488	(ABC) transporter
WP3W19E03_08290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP3W19E03_08300	COG0741	lytic transglycosylase activity
WP3W19E03_08350	COG4608	Belongs to the ABC transporter superfamily
WP3W19E03_08360	COG0444	Belongs to the ABC transporter superfamily
WP3W19E03_08380	COG4239	(ABC) transporter, permease
WP3W19E03_08390	COG4174	ABC transporter (Permease)
WP3W19E03_08400	COG4206	TonB-dependent receptor
WP3W19E03_08420	COG0811	peptide transport
WP3W19E03_08430	COG0811	peptide transport
WP3W19E03_08440	COG0848	biopolymer transport protein
WP3W19E03_08480	COG0616	signal peptide processing
WP3W19E03_08490	COG1902	pentaerythritol trinitrate reductase activity
WP3W19E03_08490	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP3W19E03_08500	COG0778	Nitroreductase
WP3W19E03_08520	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP3W19E03_08530	COG2264	protein methyltransferase activity
WP3W19E03_08540	COG0604	alcohol dehydrogenase
WP3W19E03_08550	COG0583	DNA-binding transcription factor activity
WP3W19E03_08560	COG2190	(PTS) system
WP3W19E03_08560	COG1263	PTS System
WP3W19E03_08560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP3W19E03_08570	COG4145	pantothenate transmembrane transporter activity
WP3W19E03_08590	COG0439	Biotin carboxylase
WP3W19E03_08600	COG0511	ligase activity, forming carbon-carbon bonds
WP3W19E03_08610	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WP3W19E03_08620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP3W19E03_08680	COG3381	protein complex oligomerization
WP3W19E03_08700	COG3005	denitrification pathway
WP3W19E03_08710	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_08730	COG1879	ABC-type sugar transport system periplasmic component
WP3W19E03_08740	COG2198	Histidine kinase
WP3W19E03_08740	COG0784	Response regulator, receiver
WP3W19E03_08740	COG2205	protein histidine kinase activity
WP3W19E03_08760	COG0784	Response regulator, receiver
WP3W19E03_08760	COG2198	Histidine kinase
WP3W19E03_08760	COG5002	protein histidine kinase activity
WP3W19E03_08780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WP3W19E03_08790	COG3385	transposase activity
WP3W19E03_08800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WP3W19E03_08810	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP3W19E03_08810	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP3W19E03_08840	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WP3W19E03_08850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP3W19E03_08860	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WP3W19E03_08870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WP3W19E03_08920	COG2900	Belongs to the SlyX family
WP3W19E03_08940	COG0545	Peptidyl-prolyl cis-trans isomerase
WP3W19E03_08950	COG2204	response regulator
WP3W19E03_08990	COG0737	Belongs to the 5'-nucleotidase family
WP3W19E03_09030	COG2801	Transposase and inactivated derivatives
WP3W19E03_09060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WP3W19E03_09070	COG0142	geranyltranstransferase activity
WP3W19E03_09080	COG1722	exodeoxyribonuclease VII activity
WP3W19E03_09090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP3W19E03_09100	COG1360	Flagellar Motor Protein
WP3W19E03_09130	COG1534	Rna-binding protein
WP3W19E03_09140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WP3W19E03_09160	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WP3W19E03_09170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WP3W19E03_09180	COG0149	triose-phosphate isomerase activity
WP3W19E03_09190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WP3W19E03_09200	COG0779	Required for maturation of 30S ribosomal subunits
WP3W19E03_09210	COG0195	Participates in both transcription termination and antitermination
WP3W19E03_09220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WP3W19E03_09230	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WP3W19E03_09240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WP3W19E03_09250	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WP3W19E03_09260	COG1185	polyribonucleotide nucleotidyltransferase activity
WP3W19E03_09270	COG2201	protein-glutamate methylesterase activity
WP3W19E03_09280	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WP3W19E03_09300	COG0840	transmembrane signaling receptor activity
WP3W19E03_09310	COG0835	chemotaxis
WP3W19E03_09330	COG0643	Histidine kinase
WP3W19E03_09330	COG2198	Histidine kinase
WP3W19E03_09350	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_09390	COG1280	lysine exporter protein (LysE YggA)
WP3W19E03_09400	COG0826	peptidase U32
WP3W19E03_09410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_09440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_09460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_09470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WP3W19E03_09550	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WP3W19E03_09600	COG0300	oxidoreductase activity
WP3W19E03_09830	COG2003	Belongs to the UPF0758 family
WP3W19E03_09910	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_09970	COG3041	Addiction module toxin RelE StbE family
WP3W19E03_09980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_10000	COG5377	YqaJ viral recombinase family
WP3W19E03_10050	COG0077	Prephenate dehydratase
WP3W19E03_10050	COG1605	Chorismate mutase
WP3W19E03_10110	COG3272	Protein of unknown function (DUF1722)
WP3W19E03_10120	COG0789	Transcriptional regulator
WP3W19E03_10130	COG0415	Belongs to the DNA photolyase family
WP3W19E03_10150	COG0300	oxidoreductase activity
WP3W19E03_10180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WP3W19E03_10240	COG1477	protein flavinylation
WP3W19E03_10250	COG2871	sodium ion transport
WP3W19E03_10260	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP3W19E03_10270	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP3W19E03_10280	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP3W19E03_10290	COG1805	sodium ion transport
WP3W19E03_10300	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP3W19E03_10310	COG0271	Belongs to the BolA IbaG family
WP3W19E03_10320	COG2813	Specifically methylates the guanine in position
WP3W19E03_10340	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP3W19E03_10350	COG2211	Major facilitator Superfamily
WP3W19E03_10360	COG3248	Nucleoside-binding outer membrane protein
WP3W19E03_10370	COG1666	GTP binding
WP3W19E03_10380	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WP3W19E03_10390	COG0693	protein deglycase activity
WP3W19E03_10410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP3W19E03_10420	COG0840	transmembrane signaling receptor activity
WP3W19E03_10430	COG0583	DNA-binding transcription factor activity
WP3W19E03_10450	COG2363	Small membrane protein
WP3W19E03_10460	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
WP3W19E03_10480	COG0473	3-isopropylmalate dehydrogenase activity
WP3W19E03_10490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP3W19E03_10500	COG1611	Belongs to the LOG family
WP3W19E03_10510	COG3706	GGDEF domain
WP3W19E03_10530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP3W19E03_10530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP3W19E03_10550	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
WP3W19E03_10610	COG3098	single-species biofilm formation
WP3W19E03_10620	COG0564	pseudouridine synthase activity
WP3W19E03_10660	COG1263	PTS System
WP3W19E03_10660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP3W19E03_10680	COG2171	N-acyltransferase activity
WP3W19E03_10700	COG0024	Methionine aminopeptidase
WP3W19E03_10710	COG0052	Belongs to the universal ribosomal protein uS2 family
WP3W19E03_10720	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WP3W19E03_10730	COG0528	UMP kinase activity
WP3W19E03_10740	COG0233	cytoplasmic translational termination
WP3W19E03_10750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WP3W19E03_10760	COG0575	Belongs to the CDS family
WP3W19E03_10770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WP3W19E03_10780	COG0750	zinc metalloprotease
WP3W19E03_10810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP3W19E03_10820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP3W19E03_10830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP3W19E03_10840	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP3W19E03_10850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WP3W19E03_10870	COG0825	malonyl-CoA metabolic process
WP3W19E03_10890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP3W19E03_10900	COG1115	amino acid carrier protein
WP3W19E03_10930	COG0714	Associated with various cellular activities
WP3W19E03_11020	COG3104	oligopeptide transport
WP3W19E03_11040	COG3104	oligopeptide transport
WP3W19E03_11050	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WP3W19E03_11060	COG1678	Uncharacterized ACR, COG1678
WP3W19E03_11080	COG0189	ligase activity
WP3W19E03_11090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WP3W19E03_11110	COG3091	SprT-like family
WP3W19E03_11130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WP3W19E03_11150	COG0251	oxidation-reduction process
WP3W19E03_11170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WP3W19E03_11180	COG0739	heme binding
WP3W19E03_11190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP3W19E03_11220	COG0814	amino acid
WP3W19E03_11250	COG0531	amino acid
WP3W19E03_11270	COG0488	(ABC) transporter
WP3W19E03_11290	COG3710	Transcriptional regulator
WP3W19E03_11300	COG0531	amino acid
WP3W19E03_11310	COG1982	Orn Lys Arg decarboxylase major
WP3W19E03_11320	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP3W19E03_11350	COG3590	peptidase
WP3W19E03_11370	COG2203	Gaf domain
WP3W19E03_11370	COG2199	diguanylate cyclase activity
WP3W19E03_11440	COG0366	Alpha amylase catalytic
WP3W19E03_11470	COG0463	Glycosyl transferase, family 2
WP3W19E03_11500	COG2989	Protein conserved in bacteria
WP3W19E03_11510	COG3108	Peptidase M15
WP3W19E03_11530	COG2860	membrane
WP3W19E03_11550	COG1196	nuclear chromosome segregation
WP3W19E03_11560	COG3115	cell septum assembly
WP3W19E03_11570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WP3W19E03_11610	COG0602	queuosine metabolic process
WP3W19E03_11680	COG1846	Transcriptional regulator
WP3W19E03_11700	COG0281	malic enzyme
WP3W19E03_11710	COG3290	protein histidine kinase activity
WP3W19E03_11730	COG0697	spore germination
WP3W19E03_11740	COG3385	transposase activity
WP3W19E03_11760	COG0346	lactoylglutathione lyase activity
WP3W19E03_11770	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_11780	COG5002	protein histidine kinase activity
WP3W19E03_11830	COG3142	Participates in the control of copper homeostasis
WP3W19E03_11840	COG0545	Peptidyl-prolyl cis-trans isomerase
WP3W19E03_11890	COG0678	peroxiredoxin activity
WP3W19E03_11910	COG0019	diaminopimelate decarboxylase activity
WP3W19E03_11920	COG1115	amino acid carrier protein
WP3W19E03_11930	COG0095	Lipoate-protein ligase
WP3W19E03_11940	COG2233	PERMEase
WP3W19E03_11950	COG3706	GGDEF domain
WP3W19E03_11970	COG0534	Mate efflux family protein
WP3W19E03_11990	COG0281	malic enzyme
WP3W19E03_12050	COG0733	neurotransmitter:sodium symporter activity
WP3W19E03_12060	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP3W19E03_12070	COG3706	GGDEF domain
WP3W19E03_12080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_12100	COG1032	radical SAM domain protein
WP3W19E03_12150	COG0673	inositol 2-dehydrogenase activity
WP3W19E03_12160	COG2920	part of a sulfur-relay system
WP3W19E03_12170	COG1289	transmembrane transporter activity
WP3W19E03_12180	COG0670	Belongs to the BI1 family
WP3W19E03_12210	COG1486	melibiose metabolic process
WP3W19E03_12220	COG2169	Transcriptional regulator
WP3W19E03_12220	COG1917	Cupin 2, conserved barrel domain protein
WP3W19E03_12230	COG1447	Phosphotransferase system cellobiose-specific component IIA
WP3W19E03_12240	COG2723	6-phospho-beta-galactosidase activity
WP3W19E03_12250	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP3W19E03_12260	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP3W19E03_12280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP3W19E03_12290	COG1446	asparaginase
WP3W19E03_12300	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP3W19E03_12310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP3W19E03_12320	COG1447	Phosphotransferase system cellobiose-specific component IIA
WP3W19E03_12350	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WP3W19E03_12370	COG3156	type II secretion system protein K
WP3W19E03_12380	COG4795	General secretion pathway protein
WP3W19E03_12390	COG2165	general secretion pathway protein
WP3W19E03_12410	COG2165	general secretion pathway protein
WP3W19E03_12420	COG1459	type II secretion system
WP3W19E03_12430	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP3W19E03_12470	COG3267	Type II secretory pathway component ExeA
WP3W19E03_12470	COG3409	Peptidoglycan-binding domain 1 protein
WP3W19E03_12480	COG2770	Histidine kinase
WP3W19E03_12480	COG3437	response regulator, receiver
WP3W19E03_12510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WP3W19E03_12520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WP3W19E03_12530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_12550	COG2190	(PTS) system
WP3W19E03_12560	COG3706	GGDEF domain
WP3W19E03_12570	COG1196	nuclear chromosome segregation
WP3W19E03_12570	COG3264	Mechanosensitive ion channel
WP3W19E03_12580	COG0469	pyruvate kinase activity
WP3W19E03_12600	COG3384	dioxygenase
WP3W19E03_12610	COG0419	ATPase involved in DNA repair
WP3W19E03_12620	COG0420	3'-5' exonuclease activity
WP3W19E03_12640	COG2974	May be involved in recombination
WP3W19E03_12680	COG0531	amino acid
WP3W19E03_12700	COG0531	amino acid
WP3W19E03_12740	COG1396	sequence-specific DNA binding
WP3W19E03_12740	COG1917	Cupin 2, conserved barrel domain protein
WP3W19E03_12750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP3W19E03_12860	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_12880	COG3038	cytochrome b561
WP3W19E03_12890	COG1720	tRNA m6t6A37 methyltransferase activity
WP3W19E03_12930	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WP3W19E03_12940	COG4988	ABC transporter
WP3W19E03_12950	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_12970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP3W19E03_13040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP3W19E03_13050	COG3385	transposase activity
WP3W19E03_13060	COG3550	peptidyl-serine autophosphorylation
WP3W19E03_13070	COG1396	sequence-specific DNA binding
WP3W19E03_13080	COG1988	membrane-bound metal-dependent
WP3W19E03_13130	COG0159	tryptophan synthase activity
WP3W19E03_13140	COG0133	tryptophan synthase activity
WP3W19E03_13150	COG0135	phosphoribosylanthranilate isomerase activity
WP3W19E03_13150	COG0134	indole-3-glycerol-phosphate synthase activity
WP3W19E03_13160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP3W19E03_13170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP3W19E03_13170	COG0512	Glutamine amidotransferase of anthranilate synthase
WP3W19E03_13180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WP3W19E03_13200	COG0009	L-threonylcarbamoyladenylate synthase
WP3W19E03_13220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WP3W19E03_13240	COG1946	Acyl-CoA thioesterase
WP3W19E03_13250	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WP3W19E03_13260	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WP3W19E03_13280	COG0083	homoserine kinase activity
WP3W19E03_13290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP3W19E03_13300	COG3039	Transposase
WP3W19E03_13310	COG1484	DNA-dependent DNA replication
WP3W19E03_13320	COG4584	PFAM Integrase catalytic
WP3W19E03_13340	COG1943	Transposase
WP3W19E03_13350	COG1484	DNA-dependent DNA replication
WP3W19E03_13360	COG4584	PFAM Integrase catalytic
WP3W19E03_13380	COG0675	Transposase, IS605 OrfB family
WP3W19E03_13400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP3W19E03_13440	COG1342	Belongs to the UPF0251 family
WP3W19E03_13470	COG1309	transcriptional regulator
WP3W19E03_13480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_13490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP3W19E03_13530	COG0686	Belongs to the AlaDH PNT family
WP3W19E03_13570	COG0438	transferase activity, transferring glycosyl groups
WP3W19E03_13620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WP3W19E03_13650	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
WP3W19E03_13710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP3W19E03_13760	COG1136	(ABC) transporter
WP3W19E03_13760	COG0577	efflux transmembrane transporter activity
WP3W19E03_13770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_13800	COG0675	Transposase, IS605 OrfB family
WP3W19E03_13810	COG1227	inorganic diphosphatase activity
WP3W19E03_13820	COG0497	DNA recombination
WP3W19E03_13830	COG1486	melibiose metabolic process
WP3W19E03_13840	COG0583	DNA-binding transcription factor activity
WP3W19E03_13860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WP3W19E03_13870	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WP3W19E03_13880	COG0443	Heat shock 70 kDa protein
WP3W19E03_13890	COG0484	heat shock protein binding
WP3W19E03_13900	COG3385	transposase activity
WP3W19E03_13910	COG3385	transposase activity
WP3W19E03_13970	COG1285	pathogenesis
WP3W19E03_14050	COG1566	PFAM secretion protein HlyD family protein
WP3W19E03_14060	COG0577	efflux transmembrane transporter activity
WP3W19E03_14060	COG1136	(ABC) transporter
WP3W19E03_14070	COG0577	efflux transmembrane transporter activity
WP3W19E03_14070	COG1136	(ABC) transporter
WP3W19E03_14080	COG0577	efflux transmembrane transporter activity
WP3W19E03_14080	COG1136	(ABC) transporter
WP3W19E03_14100	COG0095	Lipoate-protein ligase
WP3W19E03_14120	COG0702	epimerase
WP3W19E03_14130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP3W19E03_14140	COG1454	alcohol dehydrogenase
WP3W19E03_14160	COG0564	pseudouridine synthase activity
WP3W19E03_14220	COG1280	lysine exporter protein (LysE YggA)
WP3W19E03_14250	COG3263	regulation of cellular component size
WP3W19E03_14270	COG1876	peptidase activity
WP3W19E03_14280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP3W19E03_14290	COG1393	Belongs to the ArsC family
WP3W19E03_14310	COG3069	C4-dicarboxylate transmembrane transporter activity
WP3W19E03_14320	COG1473	amidohydrolase
WP3W19E03_14340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP3W19E03_14360	COG0017	Asparaginyl-tRNA synthetase
WP3W19E03_14390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WP3W19E03_14400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP3W19E03_14410	COG0156	8-amino-7-oxononanoate synthase activity
WP3W19E03_14420	COG1073	alpha beta
WP3W19E03_14420	COG2226	methyltransferase
WP3W19E03_14430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WP3W19E03_14440	COG0501	Belongs to the peptidase M48B family
WP3W19E03_14460	COG3217	Mosc domain protein beta barrel domain protein
WP3W19E03_14460	COG0633	Ferredoxin
WP3W19E03_14460	COG3217	Mosc domain protein beta barrel domain protein
WP3W19E03_14460	COG0633	Ferredoxin
WP3W19E03_14490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WP3W19E03_14490	COG0674	pyruvate-flavodoxin oxidoreductase activity
WP3W19E03_14490	COG1013	pyruvate-flavodoxin oxidoreductase activity
WP3W19E03_14490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WP3W19E03_14510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP3W19E03_14520	COG1607	acyl-coa hydrolase
WP3W19E03_14540	COG3021	interspecies interaction between organisms
WP3W19E03_14550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WP3W19E03_14560	COG2027	D-alanyl-D-alanine carboxypeptidase
WP3W19E03_14570	COG1061	Type III restriction enzyme res subunit
WP3W19E03_14580	COG1566	PFAM secretion protein HlyD family protein
WP3W19E03_14600	COG1966	Carbon starvation protein
WP3W19E03_14610	COG3279	Response regulator of the LytR AlgR family
WP3W19E03_14620	COG3275	phosphorelay sensor kinase activity
WP3W19E03_14630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP3W19E03_14630	COG2199	diguanylate cyclase activity
WP3W19E03_14640	COG2194	sulfuric ester hydrolase activity
WP3W19E03_14650	COG1940	carbohydrate kinase activity
WP3W19E03_14650	COG1846	Transcriptional regulator
WP3W19E03_14660	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP3W19E03_14670	COG0363	glucosamine-6-phosphate deaminase activity
WP3W19E03_14680	COG1263	PTS System
WP3W19E03_14680	COG2190	(PTS) system
WP3W19E03_14680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP3W19E03_14700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP3W19E03_14710	COG0735	belongs to the Fur family
WP3W19E03_14730	COG0716	FMN binding
WP3W19E03_14760	COG0596	Alpha beta hydrolase
WP3W19E03_14770	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WP3W19E03_14780	COG0033	Phosphoglucomutase
WP3W19E03_14790	COG2951	lytic endotransglycosylase activity
WP3W19E03_14800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WP3W19E03_14810	COG4136	ATPase activity
WP3W19E03_14820	COG4135	transport system, permease component
WP3W19E03_14830	COG4134	Bacterial extracellular solute-binding protein
WP3W19E03_14850	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP3W19E03_14870	COG0675	Transposase, IS605 OrfB family
WP3W19E03_14890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP3W19E03_14910	COG0729	surface antigen
WP3W19E03_14920	COG2911	Protein conserved in bacteria
WP3W19E03_14940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WP3W19E03_14960	COG0741	lytic transglycosylase activity
WP3W19E03_14990	COG4771	TonB-dependent receptor
WP3W19E03_15040	COG1278	Cold shock
WP3W19E03_15090	COG0697	spore germination
WP3W19E03_15100	COG1349	DNA-binding transcription factor activity
WP3W19E03_15110	COG1882	Formate acetyltransferase
WP3W19E03_15120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP3W19E03_15130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP3W19E03_15160	COG1187	pseudouridine synthase activity
WP3W19E03_15180	COG4166	transmembrane transport
WP3W19E03_15190	COG0622	Phosphoesterase
WP3W19E03_15220	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
WP3W19E03_15230	COG0835	chemotaxis
WP3W19E03_15230	COG0784	Response regulator, receiver
WP3W19E03_15240	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WP3W19E03_15250	COG1815	bacterial-type flagellum-dependent cell motility
WP3W19E03_15270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WP3W19E03_15290	COG4787	bacterial-type flagellum-dependent cell motility
WP3W19E03_15310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WP3W19E03_15320	COG1706	bacterial-type flagellum-dependent cell motility
WP3W19E03_15350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WP3W19E03_15360	COG2239	Acts as a magnesium transporter
WP3W19E03_15380	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WP3W19E03_15390	COG2716	regulation of RNA biosynthetic process
WP3W19E03_15420	COG3852	Histidine kinase
WP3W19E03_15440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WP3W19E03_15450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WP3W19E03_15460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WP3W19E03_15470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WP3W19E03_15510	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WP3W19E03_15530	COG0590	tRNA wobble adenosine to inosine editing
WP3W19E03_15540	COG0573	inorganic phosphate transmembrane transporter activity
WP3W19E03_15550	COG0581	inorganic phosphate transmembrane transporter activity
WP3W19E03_15570	COG0704	Plays a role in the regulation of phosphate uptake
WP3W19E03_15580	COG1253	flavin adenine dinucleotide binding
WP3W19E03_15610	COG0531	amino acid
WP3W19E03_15640	COG1126	abc transporter atp-binding protein
WP3W19E03_15660	COG0765	amino acid transport
WP3W19E03_15670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_15680	COG3706	GGDEF domain
WP3W19E03_15690	COG2271	Major facilitator Superfamily
WP3W19E03_15710	COG2197	response regulator
WP3W19E03_15720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP3W19E03_15760	COG1785	Belongs to the alkaline phosphatase family
WP3W19E03_15770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WP3W19E03_15780	COG3385	transposase activity
WP3W19E03_15790	COG0123	including yeast histone deacetylase and acetoin utilization protein
WP3W19E03_15810	COG1199	ATP-dependent helicase activity
WP3W19E03_15830	COG1605	Chorismate mutase
WP3W19E03_15830	COG0287	Prephenate dehydrogenase
WP3W19E03_15840	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP3W19E03_15860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP3W19E03_15870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP3W19E03_15940	COG0537	adenosine 5'-monophosphoramidase activity
WP3W19E03_15970	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WP3W19E03_15990	COG1301	dicarboxylic acid transport
WP3W19E03_16020	COG2354	Protein conserved in bacteria
WP3W19E03_16040	COG2233	PERMEase
WP3W19E03_16050	COG3150	esterase
WP3W19E03_16060	COG1252	NADH dehydrogenase
WP3W19E03_16080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP3W19E03_16090	COG3300	MHYT domain
WP3W19E03_16090	COG5001	Diguanylate cyclase
WP3W19E03_16100	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP3W19E03_16120	COG2373	Large extracellular alpha-helical protein
WP3W19E03_16130	COG4953	penicillin-binding protein 1C
WP3W19E03_16160	COG0301	tRNA thio-modification
WP3W19E03_16160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP3W19E03_16170	COG3385	transposase activity
WP3W19E03_16310	COG2801	Transposase and inactivated derivatives
WP3W19E03_16350	COG1083	cytidylyl-transferase
WP3W19E03_16380	COG2801	Transposase and inactivated derivatives
WP3W19E03_16390	COG2801	Transposase and inactivated derivatives
WP3W19E03_16420	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP3W19E03_16440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP3W19E03_16470	COG1106	Psort location Cytoplasmic, score
WP3W19E03_16560	COG3385	transposase activity
WP3W19E03_16570	COG2119	membrane
WP3W19E03_16580	COG0023	Translation Initiation Factor
WP3W19E03_16630	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_16660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_16670	COG0765	amino acid transport
WP3W19E03_16680	COG1126	abc transporter atp-binding protein
WP3W19E03_16690	COG0493	'glutamate synthase
WP3W19E03_16700	COG0067	glutamate synthase
WP3W19E03_16700	COG0069	glutamate synthase activity
WP3W19E03_16700	COG0070	glutamate synthase
WP3W19E03_16710	COG1242	4 iron, 4 sulfur cluster binding
WP3W19E03_16780	COG4584	PFAM Integrase catalytic
WP3W19E03_16790	COG1484	DNA-dependent DNA replication
WP3W19E03_16850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP3W19E03_16870	COG4804	nuclease activity
WP3W19E03_16890	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP3W19E03_16900	COG3634	alkyl hydroperoxide reductase activity
WP3W19E03_16920	COG0517	IMP dehydrogenase activity
WP3W19E03_16930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WP3W19E03_16940	COG0343	queuine tRNA-ribosyltransferase activity
WP3W19E03_16950	COG1862	Preprotein translocase
WP3W19E03_16960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP3W19E03_16970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP3W19E03_16980	COG2897	thiosulfate sulfurtransferase activity
WP3W19E03_17000	COG0826	peptidase U32
WP3W19E03_17010	COG0826	peptidase U32
WP3W19E03_17020	COG3154	lipid carrier protein
WP3W19E03_17060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WP3W19E03_17070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP3W19E03_17070	COG0574	Belongs to the PEP-utilizing enzyme family
WP3W19E03_17100	COG1464	Belongs to the NlpA lipoprotein family
WP3W19E03_17110	COG3083	sulfuric ester hydrolase activity
WP3W19E03_17120	COG3082	Protein of unknown function (DUF1414)
WP3W19E03_17130	COG3081	Nucleoid-associated protein
WP3W19E03_17150	COG1175	transmembrane transport
WP3W19E03_17160	COG3833	ABC-type maltose transport systems, permease component
WP3W19E03_17170	COG3842	ATPase activity
WP3W19E03_17220	COG0425	Belongs to the sulfur carrier protein TusA family
WP3W19E03_17230	COG4783	chaperone-mediated protein folding
WP3W19E03_17250	COG1393	Belongs to the ArsC family
WP3W19E03_17270	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
WP3W19E03_17280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_17290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP3W19E03_17300	COG2431	L-lysine efflux transmembrane transporter activity
WP3W19E03_17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_17340	COG4160	amino acid transport
WP3W19E03_17350	COG0564	pseudouridine synthase activity
WP3W19E03_17380	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WP3W19E03_17400	COG0625	glutathione transferase activity
WP3W19E03_17420	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP3W19E03_17430	COG3069	C4-dicarboxylate transmembrane transporter activity
WP3W19E03_17440	COG0367	asparagine synthase
WP3W19E03_17460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP3W19E03_17460	COG4651	solute:proton antiporter activity
WP3W19E03_17470	COG0647	UMP catabolic process
WP3W19E03_17510	COG1902	pentaerythritol trinitrate reductase activity
WP3W19E03_17520	COG1253	flavin adenine dinucleotide binding
WP3W19E03_17540	COG0247	lactate metabolic process
WP3W19E03_17540	COG0277	FAD linked oxidase domain protein
WP3W19E03_17560	COG2050	protein possibly involved in aromatic compounds catabolism
WP3W19E03_17570	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_17580	COG2056	Na+-H+ antiporter family
WP3W19E03_17590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP3W19E03_17600	COG0671	phosphoesterase, PA-phosphatase related
WP3W19E03_17610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP3W19E03_17620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP3W19E03_17640	COG0101	tRNA pseudouridine synthase activity
WP3W19E03_17650	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WP3W19E03_17660	COG0285	dihydrofolate synthase activity
WP3W19E03_17670	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WP3W19E03_17680	COG0393	Putative heavy-metal-binding
WP3W19E03_17700	COG1648	precorrin-2 dehydrogenase activity
WP3W19E03_17700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP3W19E03_17740	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_17770	COG4667	esterase of the alpha-beta hydrolase superfamily
WP3W19E03_17780	COG1619	proteins homologs of microcin C7 resistance protein MccF
WP3W19E03_17790	COG1368	sulfuric ester hydrolase activity
WP3W19E03_17820	COG2814	Major facilitator Superfamily
WP3W19E03_17850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP3W19E03_17860	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WP3W19E03_17870	COG0539	negative regulation of cytoplasmic translation
WP3W19E03_17880	COG0776	regulation of translation
WP3W19E03_17900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WP3W19E03_17940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WP3W19E03_17950	COG0602	queuosine metabolic process
WP3W19E03_17960	COG3530	Putative quorum-sensing-regulated virulence factor
WP3W19E03_17970	COG2096	Adenosyltransferase
WP3W19E03_17980	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP3W19E03_17990	COG1757	Na H antiporter
WP3W19E03_18000	COG1435	thymidine kinase activity
WP3W19E03_18030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WP3W19E03_18040	COG0326	Molecular chaperone. Has ATPase activity
WP3W19E03_18050	COG4172	Belongs to the ABC transporter superfamily
WP3W19E03_18060	COG4172	Belongs to the ABC transporter superfamily
WP3W19E03_18080	COG4168	peptide transport system, permease
WP3W19E03_18090	COG0747	negative chemotaxis
WP3W19E03_18100	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WP3W19E03_18110	COG1842	Phage shock protein A
WP3W19E03_18140	COG3106	COG3106 Predicted ATPase
WP3W19E03_18150	COG3768	UPF0283 membrane protein
WP3W19E03_18160	COG0583	DNA-binding transcription factor activity
WP3W19E03_18170	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WP3W19E03_18180	COG3842	ATPase activity
WP3W19E03_18190	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP3W19E03_18200	COG1177	transmembrane transport
WP3W19E03_18210	COG1012	belongs to the aldehyde dehydrogenase family
WP3W19E03_18230	COG2154	pterin-4-alpha-carbinolamine dehydratase
WP3W19E03_18260	COG2199	diguanylate cyclase activity
WP3W19E03_18270	COG2885	chlorophyll binding
WP3W19E03_18280	COG0861	Integral membrane protein TerC family
WP3W19E03_18310	COG1022	Amp-dependent synthetase and ligase
WP3W19E03_18340	COG2910	NAD(P)H-binding
WP3W19E03_18350	COG0583	DNA-binding transcription factor activity
WP3W19E03_18360	COG0583	DNA-binding transcription factor activity
WP3W19E03_18370	COG0583	DNA-binding transcription factor activity
WP3W19E03_18380	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WP3W19E03_18400	COG0583	DNA-binding transcription factor activity
WP3W19E03_18410	COG2723	6-phospho-beta-galactosidase activity
WP3W19E03_18420	COG1944	ATP diphosphatase activity
WP3W19E03_18430	COG2116	formate transmembrane transporter activity
WP3W19E03_18440	COG1882	Formate acetyltransferase
WP3W19E03_18450	COG2983	Belongs to the UPF0260 family
WP3W19E03_18460	COG4166	transmembrane transport
WP3W19E03_18470	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WP3W19E03_18480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WP3W19E03_18500	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP3W19E03_18510	COG1136	(ABC) transporter
WP3W19E03_18520	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP3W19E03_18530	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
WP3W19E03_18550	COG0544	peptidyl-prolyl cis-trans isomerase activity
WP3W19E03_18560	COG0740	serine-type endopeptidase activity
WP3W19E03_18570	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WP3W19E03_18580	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WP3W19E03_18590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP3W19E03_18600	COG0488	(ABC) transporter
WP3W19E03_18610	COG0582	viral genome integration into host DNA
WP3W19E03_18660	COG2974	May be involved in recombination
WP3W19E03_18740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP3W19E03_18850	COG0270	DNA (cytosine-5-)-methyltransferase activity
WP3W19E03_19240	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP3W19E03_19250	COG3162	membrane
WP3W19E03_19280	COG1024	Enoyl-CoA hydratase
WP3W19E03_19290	COG1115	amino acid carrier protein
WP3W19E03_19320	COG1584	GPR1 FUN34 yaaH family protein
WP3W19E03_19390	COG1024	Enoyl-CoA hydratase
WP3W19E03_19400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WP3W19E03_19410	COG1960	acyl-CoA dehydrogenase activity
WP3W19E03_19420	COG1960	acyl-CoA dehydrogenase activity
WP3W19E03_19430	COG1024	Enoyl-CoA hydratase
WP3W19E03_19440	COG1024	Enoyl-CoA hydratase
WP3W19E03_19460	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_19480	COG0730	response to heat
WP3W19E03_19520	COG0640	Transcriptional regulator
WP3W19E03_19550	COG0798	PFAM Bile acid sodium symporter
WP3W19E03_19560	COG1393	Belongs to the ArsC family
WP3W19E03_19630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WP3W19E03_19650	COG2801	Transposase and inactivated derivatives
WP3W19E03_19660	COG5001	Diguanylate cyclase
WP3W19E03_19660	COG4251	negative regulation of phosphorylation
WP3W19E03_19660	COG3706	GGDEF domain
WP3W19E03_19660	COG2203	Gaf domain
WP3W19E03_19670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP3W19E03_19680	COG3437	response regulator, receiver
WP3W19E03_19710	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WP3W19E03_19720	COG0437	4 iron, 4 sulfur cluster binding
WP3W19E03_19730	COG5557	Pfam Polysulphide reductase, NrfD
WP3W19E03_19740	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WP3W19E03_19750	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP3W19E03_19760	COG1773	rubredoxin
WP3W19E03_19780	COG0601	transmembrane transport
WP3W19E03_19790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP3W19E03_19820	COG3842	ATPase activity
WP3W19E03_19830	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WP3W19E03_19850	COG0375	protein maturation
WP3W19E03_19860	COG0309	Hydrogenase expression formation protein (HypE)
WP3W19E03_19880	COG0298	carbon dioxide binding
WP3W19E03_19890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WP3W19E03_19910	COG1921	L-seryl-tRNASec selenium transferase activity
WP3W19E03_19920	COG3385	transposase activity
WP3W19E03_19930	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP3W19E03_19950	COG3260	NADH ubiquinone oxidoreductase 20
WP3W19E03_19960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP3W19E03_19970	COG3261	NADH dehydrogenase
WP3W19E03_19970	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
WP3W19E03_19980	COG0650	Formate hydrogenlyase subunit 4
WP3W19E03_19990	COG0651	ATP synthesis coupled electron transport
WP3W19E03_20000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP3W19E03_20030	COG2801	Transposase and inactivated derivatives
WP3W19E03_20050	COG0583	DNA-binding transcription factor activity
WP3W19E03_20070	COG1560	Kdo2-lipid A biosynthetic process
WP3W19E03_20080	COG1560	Kdo2-lipid A biosynthetic process
WP3W19E03_20110	COG2203	Gaf domain
WP3W19E03_20110	COG2199	diguanylate cyclase activity
WP3W19E03_20130	COG0417	DNA replication proofreading
WP3W19E03_20160	COG1451	nucleotide metabolic process
WP3W19E03_20190	COG3069	C4-dicarboxylate transmembrane transporter activity
WP3W19E03_20220	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WP3W19E03_20220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP3W19E03_20230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP3W19E03_20240	COG0569	domain protein
WP3W19E03_20240	COG2985	domain, Protein
WP3W19E03_20250	COG0556	nucleotide-excision repair
WP3W19E03_20270	COG0586	Pfam SNARE associated Golgi protein
WP3W19E03_20280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WP3W19E03_20290	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP3W19E03_20320	COG4681	YaeQ
WP3W19E03_20370	COG0307	riboflavin synthase, alpha
WP3W19E03_20380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP3W19E03_20390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_20420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP3W19E03_20430	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WP3W19E03_20440	COG0697	spore germination
WP3W19E03_20450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WP3W19E03_20530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP3W19E03_20540	COG3099	Belongs to the UPF0263 family
WP3W19E03_20550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WP3W19E03_20560	COG2894	cell division
WP3W19E03_20570	COG0850	regulation of cytokinetic process
WP3W19E03_20580	COG3100	YcgL domain-containing protein
WP3W19E03_20590	COG1760	l-serine dehydratase
WP3W19E03_20610	COG1760	l-serine dehydratase
WP3W19E03_20620	COG3123	guanosine phosphorylase activity
WP3W19E03_20650	COG0205	6-phosphofructokinase activity
WP3W19E03_20670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WP3W19E03_20680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP3W19E03_20700	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WP3W19E03_20710	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WP3W19E03_20720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP3W19E03_20800	COG0641	radical SAM
WP3W19E03_20810	COG5433	transposase activity
WP3W19E03_20820	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP3W19E03_20840	COG5433	transposase activity
WP3W19E03_20900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP3W19E03_20910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP3W19E03_20920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP3W19E03_20940	COG0549	Belongs to the carbamate kinase family
WP3W19E03_20950	COG0697	spore germination
WP3W19E03_20970	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WP3W19E03_20970	COG3608	succinylglutamate desuccinylase aspartoacylase
WP3W19E03_20980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WP3W19E03_20990	COG2068	MobA-Related Protein
WP3W19E03_21000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP3W19E03_21000	COG0493	'glutamate synthase
WP3W19E03_21010	COG0402	S-adenosylhomocysteine deaminase activity
WP3W19E03_21020	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WP3W19E03_21030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP3W19E03_21030	COG2080	2 iron, 2 sulfur cluster binding
WP3W19E03_21040	COG2233	PERMEase
WP3W19E03_21050	COG0402	S-adenosylhomocysteine deaminase activity
WP3W19E03_21060	COG2252	PERMEase
WP3W19E03_21070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP3W19E03_21080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP3W19E03_21090	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WP3W19E03_21100	COG2080	2 iron, 2 sulfur cluster binding
WP3W19E03_21110	COG3134	Outer membrane lipoprotein
WP3W19E03_21130	COG1288	antiporter activity
WP3W19E03_21140	COG0318	PFAM AMP-dependent synthetase and ligase
WP3W19E03_21150	COG3706	GGDEF domain
WP3W19E03_21180	COG0107	imidazoleglycerol-phosphate synthase activity
WP3W19E03_21190	COG0784	Response regulator, receiver
WP3W19E03_21190	COG2198	Histidine kinase
WP3W19E03_21190	COG2205	protein histidine kinase activity
WP3W19E03_21210	COG3437	response regulator, receiver
WP3W19E03_21220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WP3W19E03_21230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WP3W19E03_21240	COG0131	Imidazoleglycerol-phosphate dehydratase
WP3W19E03_21240	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP3W19E03_21250	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WP3W19E03_21260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WP3W19E03_21270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WP3W19E03_21290	COG1199	ATP-dependent helicase activity
WP3W19E03_21300	COG1214	PFAM Peptidase M22, glycoprotease
WP3W19E03_21320	COG2267	carboxylic ester hydrolase activity
WP3W19E03_21330	COG0318	PFAM AMP-dependent synthetase and ligase
WP3W19E03_21350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP3W19E03_21360	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WP3W19E03_21370	COG0709	Synthesizes selenophosphate from selenide and ATP
WP3W19E03_21400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP3W19E03_21410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WP3W19E03_21420	COG0840	transmembrane signaling receptor activity
WP3W19E03_21430	COG1254	Belongs to the acylphosphatase family
WP3W19E03_21450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP3W19E03_21450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP3W19E03_21460	COG0489	protein tyrosine kinase activity
WP3W19E03_21470	COG0572	uridine kinase
WP3W19E03_21480	COG0717	Belongs to the dCTP deaminase family
WP3W19E03_21490	COG0306	phosphate transporter
WP3W19E03_21500	COG1530	ribonuclease E activity
WP3W19E03_21510	COG0564	pseudouridine synthase activity
WP3W19E03_21520	COG0546	phosphoglycolate phosphatase activity
WP3W19E03_21560	COG0583	DNA-binding transcription factor activity
WP3W19E03_21570	COG0424	maF-like protein
WP3W19E03_21590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WP3W19E03_21600	COG0416	fatty acid biosynthetic process
WP3W19E03_21610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WP3W19E03_21630	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_21640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP3W19E03_21660	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WP3W19E03_21670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WP3W19E03_21680	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WP3W19E03_21690	COG0470	DNA polymerase III
WP3W19E03_21700	COG0084	hydrolase, TatD family'
WP3W19E03_21730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP3W19E03_21730	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WP3W19E03_21810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_21860	COG1192	Involved in chromosome partitioning
WP3W19E03_21940	COG3041	Addiction module toxin RelE StbE family
WP3W19E03_21950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_22020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WP3W19E03_22110	COG0110	maltose O-acetyltransferase activity
WP3W19E03_22130	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WP3W19E03_22240	COG0789	Transcriptional regulator
WP3W19E03_22260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_22340	COG3008	intermembrane lipid transfer
WP3W19E03_22350	COG2995	paraquat-inducible protein a
WP3W19E03_22370	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WP3W19E03_22380	COG0372	Belongs to the citrate synthase family
WP3W19E03_22480	COG5433	transposase activity
WP3W19E03_22490	COG4221	oxidoreductase activity
WP3W19E03_22500	COG0596	Alpha beta hydrolase
WP3W19E03_22510	COG3141	response to X-ray
WP3W19E03_22560	COG1067	ATP-dependent peptidase activity
WP3W19E03_22570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP3W19E03_22610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP3W19E03_22610	COG0116	Belongs to the methyltransferase superfamily
WP3W19E03_22620	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WP3W19E03_22630	COG0254	rRNA binding
WP3W19E03_22650	COG0167	dihydroorotate dehydrogenase activity
WP3W19E03_22660	COG2902	Dehydrogenase
WP3W19E03_22680	COG0308	aminopeptidase N
WP3W19E03_22700	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
WP3W19E03_22710	COG1956	GAF domain-containing protein
WP3W19E03_22740	COG3278	Belongs to the heme-copper respiratory oxidase family
WP3W19E03_22770	COG2010	Cytochrome c
WP3W19E03_22790	COG2217	Heavy metal translocating P-type atpase
WP3W19E03_22820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP3W19E03_22830	COG0589	response to stress
WP3W19E03_22840	COG0037	tRNA processing
WP3W19E03_22890	COG1177	transmembrane transport
WP3W19E03_22920	COG5654	RES domain protein
WP3W19E03_22930	COG0625	glutathione transferase activity
WP3W19E03_22940	COG1869	D-ribose catabolic process
WP3W19E03_22950	COG1129	ABC transporter
WP3W19E03_22960	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP3W19E03_22970	COG1879	ABC-type sugar transport system periplasmic component
WP3W19E03_22980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_22990	COG1609	Transcriptional regulator
WP3W19E03_23030	COG2205	protein histidine kinase activity
WP3W19E03_23030	COG0784	Response regulator, receiver
WP3W19E03_23040	COG0776	regulation of translation
WP3W19E03_23050	COG0072	phenylalanine-tRNA ligase activity
WP3W19E03_23050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP3W19E03_23060	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WP3W19E03_23070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WP3W19E03_23080	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WP3W19E03_23090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WP3W19E03_23100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WP3W19E03_23140	COG0366	Alpha amylase catalytic
WP3W19E03_23160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP3W19E03_23180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP3W19E03_23190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP3W19E03_23200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP3W19E03_23210	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WP3W19E03_23220	COG3313	Fe-S protein
WP3W19E03_23230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP3W19E03_23230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP3W19E03_23230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WP3W19E03_23240	COG1105	Belongs to the carbohydrate kinase PfkB family
WP3W19E03_23250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_23250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_23260	COG1609	Transcriptional regulator
WP3W19E03_23270	COG0814	amino acid
WP3W19E03_23280	COG3788	relative of glutathione S-transferase, MAPEG superfamily
WP3W19E03_23290	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_23310	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WP3W19E03_23320	COG2890	protein-(glutamine-N5) methyltransferase activity
WP3W19E03_23330	COG2840	Smr protein MutS2
WP3W19E03_23340	COG3706	GGDEF domain
WP3W19E03_23360	COG3791	Glutathione-dependent formaldehyde-activating
WP3W19E03_23390	COG2824	Alkylphosphonate utilization operon protein PhnA
WP3W19E03_23420	COG0494	nUDIX hydrolase
WP3W19E03_23430	COG0814	amino acid
WP3W19E03_23450	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
WP3W19E03_23460	COG0514	ATP-dependent DNA helicase (RecQ)
WP3W19E03_23470	COG2766	serine protein kinase
WP3W19E03_23480	COG2718	Belongs to the UPF0229 family
WP3W19E03_23490	COG2719	SpoVR family
WP3W19E03_23500	COG1024	Enoyl-CoA hydratase
WP3W19E03_23500	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP3W19E03_23510	COG0183	Belongs to the thiolase family
WP3W19E03_23520	COG0714	Associated with various cellular activities
WP3W19E03_23560	COG2304	oxidoreductase activity
WP3W19E03_23580	COG1595	DNA-templated transcription, initiation
WP3W19E03_23600	COG2067	long-chain fatty acid transport protein
WP3W19E03_23610	COG2067	long-chain fatty acid transport protein
WP3W19E03_23620	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
WP3W19E03_23650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WP3W19E03_23670	COG1643	Atp-dependent helicase
WP3W19E03_23680	COG0617	tRNA 3'-terminal CCA addition
WP3W19E03_23680	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WP3W19E03_23680	COG0517	IMP dehydrogenase activity
WP3W19E03_23690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP3W19E03_23700	COG3119	arylsulfatase activity
WP3W19E03_23710	COG0714	Associated with various cellular activities
WP3W19E03_23740	COG2304	oxidoreductase activity
WP3W19E03_23800	COG0641	radical SAM
WP3W19E03_23810	COG2326	polyphosphate kinase activity
WP3W19E03_23880	COG1160	GTP binding
WP3W19E03_23910	COG5433	transposase activity
WP3W19E03_23920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WP3W19E03_23930	COG2925	Exonuclease
WP3W19E03_23950	COG3345	alpha-galactosidase
WP3W19E03_23960	COG1380	Effector of murein hydrolase LrgA
WP3W19E03_23970	COG1346	cytolysis
WP3W19E03_23980	COG0295	cytidine deaminase activity
WP3W19E03_23990	COG3033	Beta-eliminating lyase
WP3W19E03_24010	COG3046	protein related to deoxyribodipyrimidine photolyase
WP3W19E03_24020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP3W19E03_24030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP3W19E03_24050	COG3604	Transcriptional regulator
WP3W19E03_24080	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP3W19E03_24110	COG3158	transport of potassium into the cell
WP3W19E03_24140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
WP3W19E03_24170	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WP3W19E03_24190	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WP3W19E03_24200	COG2832	Protein of unknown function (DUF454)
WP3W19E03_24210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP3W19E03_24240	COG1011	Hydrolase
WP3W19E03_24250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP3W19E03_24280	COG3593	DNA synthesis involved in DNA repair
WP3W19E03_24340	COG0730	response to heat
WP3W19E03_24360	COG1940	carbohydrate kinase activity
WP3W19E03_24360	COG1846	Transcriptional regulator
WP3W19E03_24370	COG0840	transmembrane signaling receptor activity
WP3W19E03_24400	COG3012	SEC-C Motif Domain Protein
WP3W19E03_24410	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WP3W19E03_24420	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
WP3W19E03_24430	COG0247	lactate metabolic process
WP3W19E03_24470	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WP3W19E03_24480	COG0437	4 iron, 4 sulfur cluster binding
WP3W19E03_24490	COG3301	Polysulphide reductase, NrfD
WP3W19E03_24500	COG1138	Cytochrome C-type biogenesis protein
WP3W19E03_24520	COG3088	subunit of a heme lyase
WP3W19E03_24520	COG4235	cytochrome complex assembly
WP3W19E03_24590	COG0045	succinate-CoA ligase (ADP-forming) activity
WP3W19E03_24600	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP3W19E03_24610	COG0567	Dehydrogenase, E1 component
WP3W19E03_24630	COG1053	succinate dehydrogenase
WP3W19E03_24640	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WP3W19E03_24710	COG1742	UPF0060 membrane protein
WP3W19E03_24740	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP3W19E03_24770	COG2501	S4 domain
WP3W19E03_24790	COG1132	(ABC) transporter
WP3W19E03_24800	COG1132	(ABC) transporter
WP3W19E03_24820	COG3118	belongs to the thioredoxin family
WP3W19E03_24830	COG0471	metal ion transport
WP3W19E03_24840	COG0058	SHG alpha-glucan phosphorylase activity
WP3W19E03_24890	COG0697	spore germination
WP3W19E03_24910	COG2062	phosphohistidine phosphatase, SixA
WP3W19E03_24920	COG1025	Belongs to the peptidase M16 family
WP3W19E03_24970	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP3W19E03_24970	COG0519	Catalyzes the synthesis of GMP from XMP
WP3W19E03_24980	COG0516	GMP reductase activity
WP3W19E03_24980	COG0517	IMP dehydrogenase activity
WP3W19E03_24990	COG1278	Cold shock
WP3W19E03_25000	COG1570	exodeoxyribonuclease VII activity
WP3W19E03_25010	COG1181	Belongs to the D-alanine--D-alanine ligase family
WP3W19E03_25030	COG0386	Belongs to the glutathione peroxidase family
WP3W19E03_25040	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_25060	COG0840	transmembrane signaling receptor activity
WP3W19E03_25070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP3W19E03_25080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WP3W19E03_25090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WP3W19E03_25190	COG5001	Diguanylate cyclase
WP3W19E03_25190	COG3300	MHYT domain
WP3W19E03_25220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_25240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WP3W19E03_25250	COG0563	adenylate kinase activity
WP3W19E03_25270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WP3W19E03_25280	COG1286	toxin biosynthetic process
WP3W19E03_25290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WP3W19E03_25300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WP3W19E03_25310	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WP3W19E03_25320	COG1674	ftsk spoiiie
WP3W19E03_25320	COG0531	amino acid
WP3W19E03_25340	COG0686	Belongs to the AlaDH PNT family
WP3W19E03_25350	COG0492	ferredoxin-NADP+ reductase activity
WP3W19E03_25360	COG3706	GGDEF domain
WP3W19E03_25370	COG3134	Outer membrane lipoprotein
WP3W19E03_25380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WP3W19E03_25390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WP3W19E03_25400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WP3W19E03_25410	COG0542	response to heat
WP3W19E03_25420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WP3W19E03_25430	COG1278	Cold shock
WP3W19E03_25440	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WP3W19E03_25470	COG1484	DNA-dependent DNA replication
WP3W19E03_25490	COG3039	Transposase
WP3W19E03_25500	COG3039	Transposase
WP3W19E03_25670	COG3550	peptidyl-serine autophosphorylation
WP3W19E03_25680	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WP3W19E03_25680	COG0392	lysyltransferase activity
WP3W19E03_25700	COG0659	secondary active sulfate transmembrane transporter activity
WP3W19E03_25790	COG2814	Major facilitator Superfamily
WP3W19E03_25820	COG1136	(ABC) transporter
WP3W19E03_25860	COG0596	Alpha beta hydrolase
WP3W19E03_25900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP3W19E03_25910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WP3W19E03_25910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP3W19E03_25920	COG0527	aspartate kinase activity
WP3W19E03_25940	COG3385	transposase activity
WP3W19E03_25970	COG0778	Nitroreductase
WP3W19E03_25980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
WP3W19E03_25990	COG3300	MHYT domain
WP3W19E03_25990	COG5001	Diguanylate cyclase
WP3W19E03_26000	COG0583	DNA-binding transcription factor activity
WP3W19E03_26020	COG3437	response regulator, receiver
WP3W19E03_26070	COG4989	oxidoreductase activity
WP3W19E03_26080	COG0724	RNA recognition motif
WP3W19E03_26100	COG1126	abc transporter atp-binding protein
WP3W19E03_26110	COG0765	amino acid transport
WP3W19E03_26120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_26130	COG0765	amino acid transport
WP3W19E03_26140	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
WP3W19E03_26160	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WP3W19E03_26180	COG3385	transposase activity
WP3W19E03_26200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP3W19E03_26210	COG1360	Flagellar Motor Protein
WP3W19E03_26220	COG4771	TonB-dependent receptor
WP3W19E03_26230	COG1770	oligopeptidase
WP3W19E03_26270	COG3385	transposase activity
WP3W19E03_26280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP3W19E03_26290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP3W19E03_26300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP3W19E03_26300	COG0649	NAD binding
WP3W19E03_26310	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
WP3W19E03_26330	COG1034	ATP synthesis coupled electron transport
WP3W19E03_26340	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WP3W19E03_26350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP3W19E03_26360	COG0839	Belongs to the complex I subunit 6 family
WP3W19E03_26370	COG0713	ATP synthesis coupled electron transport
WP3W19E03_26390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP3W19E03_26400	COG1007	ATP synthesis coupled electron transport
WP3W19E03_26410	COG0047	phosphoribosylformylglycinamidine synthase activity
WP3W19E03_26410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WP3W19E03_26420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP3W19E03_26440	COG1645	bacterial-type flagellum-dependent swarming motility
WP3W19E03_26450	COG1160	GTP binding
WP3W19E03_26460	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP3W19E03_26470	COG2976	Protein conserved in bacteria
WP3W19E03_26480	COG0124	histidyl-tRNA synthetase
WP3W19E03_26520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WP3W19E03_26530	COG0105	UTP biosynthetic process
WP3W19E03_26560	COG0633	Ferredoxin
WP3W19E03_26570	COG0443	Heat shock 70 kDa protein
WP3W19E03_26580	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP3W19E03_26600	COG0822	iron-sulfur transferase activity
WP3W19E03_26610	COG1104	cysteine desulfurase activity
WP3W19E03_26620	COG1959	2 iron, 2 sulfur cluster binding
WP3W19E03_26640	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP3W19E03_26640	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP3W19E03_26650	COG0509	glycine decarboxylation via glycine cleavage system
WP3W19E03_26660	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WP3W19E03_26670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP3W19E03_26680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP3W19E03_26710	COG2814	Major facilitator Superfamily
WP3W19E03_26720	COG0625	glutathione transferase activity
WP3W19E03_26760	COG0483	inositol monophosphate 1-phosphatase activity
WP3W19E03_26780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP3W19E03_26820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WP3W19E03_26830	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WP3W19E03_26840	COG2089	acid synthase
WP3W19E03_26870	COG5433	transposase activity
WP3W19E03_26880	COG0673	inositol 2-dehydrogenase activity
WP3W19E03_26890	COG1083	cytidylyl-transferase
WP3W19E03_26900	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_26950	COG0582	viral genome integration into host DNA
WP3W19E03_26970	COG0322	excinuclease ABC activity
WP3W19E03_26980	COG2197	response regulator
WP3W19E03_26990	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WP3W19E03_27000	COG2835	tetraacyldisaccharide 4'-kinase activity
WP3W19E03_27010	COG1663	tetraacyldisaccharide 4'-kinase activity
WP3W19E03_27030	COG0658	competence protein
WP3W19E03_27030	COG2333	competence protein COMEC
WP3W19E03_27060	COG1448	Aminotransferase
WP3W19E03_27080	COG0583	DNA-binding transcription factor activity
WP3W19E03_27090	COG3085	chromosome segregation
WP3W19E03_27100	COG4574	serine-type endopeptidase inhibitor activity
WP3W19E03_27110	COG0584	glycerophosphoryl diester phosphodiesterase
WP3W19E03_27130	COG1349	DNA-binding transcription factor activity
WP3W19E03_27140	COG2271	Major facilitator Superfamily
WP3W19E03_27150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP3W19E03_27160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WP3W19E03_27170	COG0583	DNA-binding transcription factor activity
WP3W19E03_27210	COG0656	L-ascorbic acid biosynthetic process
WP3W19E03_27230	COG2814	Major facilitator Superfamily
WP3W19E03_27260	COG3220	belongs to the UPF0276 family
WP3W19E03_27300	COG1294	oxidase, subunit
WP3W19E03_27320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP3W19E03_27330	COG2979	Protein of unknown function (DUF533)
WP3W19E03_27370	COG0583	DNA-binding transcription factor activity
WP3W19E03_27390	COG2807	transmembrane transport
WP3W19E03_27400	COG1187	pseudouridine synthase activity
WP3W19E03_27420	COG0346	lactoylglutathione lyase activity
WP3W19E03_27470	COG0270	DNA (cytosine-5-)-methyltransferase activity
WP3W19E03_27480	COG4657	Part of a membrane complex involved in electron transport
WP3W19E03_27490	COG2878	Part of a membrane complex involved in electron transport
WP3W19E03_27510	COG4658	electron transport chain
WP3W19E03_27520	COG4659	FMN binding
WP3W19E03_27530	COG4660	Part of a membrane complex involved in electron transport
WP3W19E03_27540	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WP3W19E03_27550	COG0346	lactoylglutathione lyase activity
WP3W19E03_27560	COG3385	transposase activity
WP3W19E03_27570	COG3385	transposase activity
WP3W19E03_27660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WP3W19E03_27670	COG0505	Belongs to the CarA family
WP3W19E03_27700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WP3W19E03_27720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WP3W19E03_27730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WP3W19E03_27740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP3W19E03_27750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WP3W19E03_27760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP3W19E03_27770	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
WP3W19E03_27830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP3W19E03_27840	COG0861	Integral membrane protein TerC family
WP3W19E03_27870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP3W19E03_27880	COG0601	transmembrane transport
WP3W19E03_27900	COG2095	MarC family integral membrane protein
WP3W19E03_27910	COG1012	belongs to the aldehyde dehydrogenase family
WP3W19E03_27910	COG1454	alcohol dehydrogenase
WP3W19E03_27920	COG0217	transcriptional regulatory protein
WP3W19E03_27930	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WP3W19E03_27950	COG1801	Protein of unknown function DUF72
WP3W19E03_27960	COG4106	trans-aconitate 2-methyltransferase activity
WP3W19E03_27970	COG0500	methyltransferase
WP3W19E03_28010	COG0450	alkyl hydroperoxide reductase
WP3W19E03_28020	COG0583	DNA-binding transcription factor activity
WP3W19E03_28030	COG0791	NLP P60 protein
WP3W19E03_28050	COG0583	DNA-binding transcription factor activity
WP3W19E03_28060	COG2610	gluconate transmembrane transporter activity
WP3W19E03_28070	COG3048	D-serine ammonia-lyase activity
WP3W19E03_28090	COG0538	isocitrate dehydrogenase activity
WP3W19E03_28100	COG2207	Transcriptional regulator
WP3W19E03_28120	COG5433	transposase activity
WP3W19E03_28130	COG3537	Alpha-1,2-mannosidase
WP3W19E03_28200	COG3537	Alpha-1,2-mannosidase
WP3W19E03_28210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP3W19E03_28240	COG4521	taurine ABC transporter
WP3W19E03_28250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
WP3W19E03_28260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WP3W19E03_28270	COG2175	clavaminate synthase activity
WP3W19E03_28280	COG3152	Membrane
WP3W19E03_28350	COG1309	transcriptional regulator
WP3W19E03_28410	COG0534	Mate efflux family protein
WP3W19E03_28430	COG2841	Protein conserved in bacteria
WP3W19E03_28450	COG5002	protein histidine kinase activity
WP3W19E03_28450	COG5001	Diguanylate cyclase
WP3W19E03_28460	COG3132	Protein of unknown function, DUF480
WP3W19E03_28520	COG0708	Exodeoxyribonuclease III
WP3W19E03_28570	COG1122	ATPase activity
WP3W19E03_28650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_28660	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP3W19E03_28680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WP3W19E03_28690	COG1120	ATPase activity
WP3W19E03_28700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP3W19E03_28710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP3W19E03_28730	COG4771	TonB-dependent receptor
WP3W19E03_28740	COG2375	cellular response to nickel ion
WP3W19E03_28750	COG0784	Response regulator, receiver
WP3W19E03_28750	COG3437	response regulator, receiver
WP3W19E03_28780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP3W19E03_28790	COG4974	Belongs to the 'phage' integrase family
WP3W19E03_28860	COG5433	transposase activity
WP3W19E03_28900	COG2194	sulfuric ester hydrolase activity
WP3W19E03_28970	COG0671	phosphoesterase, PA-phosphatase related
WP3W19E03_28990	COG2132	Multicopper oxidase
WP3W19E03_29010	COG1484	DNA-dependent DNA replication
WP3W19E03_29020	COG4584	PFAM Integrase catalytic
WP3W19E03_29050	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP3W19E03_29150	COG0328	RNA-DNA hybrid ribonuclease activity
WP3W19E03_29160	COG2226	methyltransferase
WP3W19E03_29170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP3W19E03_29180	COG1388	LysM domain
WP3W19E03_29180	COG0741	lytic transglycosylase activity
WP3W19E03_29240	COG1388	LysM domain
WP3W19E03_29240	COG1376	ErfK ybiS ycfS ynhG family protein
WP3W19E03_29260	COG0471	metal ion transport
WP3W19E03_29280	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
WP3W19E03_29290	COG0791	NLP P60 protein
WP3W19E03_29330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP3W19E03_29340	COG0788	formyltetrahydrofolate deformylase activity
WP3W19E03_29360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP3W19E03_29390	COG0739	heme binding
WP3W19E03_29390	COG0741	lytic transglycosylase activity
WP3W19E03_29390	COG1196	nuclear chromosome segregation
WP3W19E03_29400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP3W19E03_29430	COG0436	Aminotransferase
WP3W19E03_29440	COG1288	antiporter activity
WP3W19E03_29450	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP3W19E03_29470	COG2964	Protein conserved in bacteria
WP3W19E03_29480	COG3681	Belongs to the UPF0597 family
WP3W19E03_29490	COG0251	oxidation-reduction process
WP3W19E03_29500	COG0814	amino acid
WP3W19E03_29540	COG1166	arginine decarboxylase activity
WP3W19E03_29550	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP3W19E03_29580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WP3W19E03_29600	COG2353	YceI-like domain
WP3W19E03_29610	COG0583	DNA-binding transcription factor activity
WP3W19E03_29630	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WP3W19E03_29640	COG0840	transmembrane signaling receptor activity
WP3W19E03_29650	COG0302	gtp cyclohydrolase
WP3W19E03_29670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP3W19E03_29690	COG2267	carboxylic ester hydrolase activity
WP3W19E03_29700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WP3W19E03_29730	COG0314	molybdopterin synthase activity
WP3W19E03_29740	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WP3W19E03_29750	COG0315	cyclic pyranopterin monophosphate synthase activity
WP3W19E03_29760	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP3W19E03_29770	COG3005	denitrification pathway
WP3W19E03_29790	COG0348	domain, Protein
WP3W19E03_29800	COG0437	4 iron, 4 sulfur cluster binding
WP3W19E03_29810	COG0243	molybdopterin cofactor binding
WP3W19E03_29830	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP3W19E03_29840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WP3W19E03_29850	COG3850	Histidine kinase
WP3W19E03_29860	COG2197	response regulator
WP3W19E03_29880	COG2205	protein histidine kinase activity
WP3W19E03_29880	COG0784	Response regulator, receiver
WP3W19E03_29920	COG0121	glutamine amidotransferase
WP3W19E03_29930	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP3W19E03_29940	COG1960	acyl-CoA dehydrogenase activity
WP3W19E03_29950	COG1473	amidohydrolase
WP3W19E03_29960	COG2914	Belongs to the UPF0125 (RnfH) family
WP3W19E03_29970	COG2867	negative regulation of translational initiation
WP3W19E03_29980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WP3W19E03_29990	COG0582	viral genome integration into host DNA
WP3W19E03_30030	COG4251	negative regulation of phosphorylation
WP3W19E03_30050	COG3039	Transposase
WP3W19E03_30070	COG1366	Belongs to the anti-sigma-factor antagonist family
WP3W19E03_30070	COG2202	Pas domain
WP3W19E03_30090	COG5433	transposase activity
WP3W19E03_30150	COG2862	Uncharacterized protein family, UPF0114
WP3W19E03_30190	COG5499	transcription regulator containing HTH domain
WP3W19E03_30240	COG4584	PFAM Integrase catalytic
WP3W19E03_30250	COG1484	DNA-dependent DNA replication
WP3W19E03_30270	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WP3W19E03_30290	COG1960	acyl-CoA dehydrogenase activity
WP3W19E03_30300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP3W19E03_30320	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WP3W19E03_30350	COG1317	bacterial-type flagellum organization
WP3W19E03_30490	COG5433	transposase activity
WP3W19E03_30550	COG0457	Tetratricopeptide repeat
WP3W19E03_30690	COG4790	Type iii secretion
WP3W19E03_30700	COG4794	Type iii secretion
WP3W19E03_30710	COG4791	protein targeting
WP3W19E03_30720	COG4792	protein secretion
WP3W19E03_30750	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP3W19E03_30760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP3W19E03_30760	COG1263	PTS System
WP3W19E03_30770	COG1609	Transcriptional regulator
WP3W19E03_30800	COG0737	Belongs to the 5'-nucleotidase family
WP3W19E03_30820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_30820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP3W19E03_30820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP3W19E03_30860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP3W19E03_30880	COG1187	pseudouridine synthase activity
WP3W19E03_30890	COG1051	belongs to the nudix hydrolase family
WP3W19E03_30900	COG0482	sulfurtransferase activity
WP3W19E03_30910	COG2915	High frequency lysogenization protein hflD homolog
WP3W19E03_30920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WP3W19E03_30930	COG2850	peptidyl-arginine hydroxylation
WP3W19E03_30970	COG0625	glutathione transferase activity
WP3W19E03_30980	COG0259	pyridoxamine-phosphate oxidase activity
WP3W19E03_31030	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP3W19E03_31030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP3W19E03_31040	COG0251	oxidation-reduction process
WP3W19E03_31050	COG1882	Formate acetyltransferase
WP3W19E03_31060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP3W19E03_31080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP3W19E03_31090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WP3W19E03_31110	COG3385	transposase activity
WP3W19E03_31120	COG2853	Lipoprotein
WP3W19E03_31140	COG4235	cytochrome complex assembly
WP3W19E03_31140	COG3088	subunit of a heme lyase
WP3W19E03_31150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP3W19E03_31160	COG1138	Cytochrome C-type biogenesis protein
WP3W19E03_31170	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WP3W19E03_31180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP3W19E03_31190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP3W19E03_31200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP3W19E03_31230	COG0835	chemotaxis
WP3W19E03_31250	COG1192	Involved in chromosome partitioning
WP3W19E03_31260	COG1360	Flagellar Motor Protein
WP3W19E03_31270	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP3W19E03_31280	COG2201	protein-glutamate methylesterase activity
WP3W19E03_31290	COG0643	Histidine kinase
WP3W19E03_31290	COG2198	Histidine kinase
WP3W19E03_31290	COG0784	Response regulator, receiver
WP3W19E03_31300	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WP3W19E03_31350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WP3W19E03_31370	COG1684	flagellar biosynthetic protein fliR
WP3W19E03_31480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WP3W19E03_31500	COG1677	Flagellar hook-basal body complex protein FliE
WP3W19E03_31520	COG3385	transposase activity
WP3W19E03_31540	COG0469	pyruvate kinase activity
WP3W19E03_31550	COG1737	Transcriptional regulator
WP3W19E03_31560	COG0837	glucose binding
WP3W19E03_31620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP3W19E03_31640	COG0281	malic enzyme
WP3W19E03_31690	COG0437	4 iron, 4 sulfur cluster binding
WP3W19E03_31700	COG3383	formate dehydrogenase (NAD+) activity
WP3W19E03_31700	COG3383	formate dehydrogenase (NAD+) activity
WP3W19E03_31790	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WP3W19E03_31810	COG3852	Histidine kinase
WP3W19E03_31820	COG2204	response regulator
WP3W19E03_31840	COG4662	Binding-protein-dependent transport system inner membrane component
WP3W19E03_31860	COG0746	molybdenum cofactor guanylyltransferase activity
WP3W19E03_31870	COG0303	'Molybdopterin
WP3W19E03_31880	COG1289	transmembrane transporter activity
WP3W19E03_31940	COG2205	protein histidine kinase activity
WP3W19E03_31940	COG0784	Response regulator, receiver
WP3W19E03_31980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP3W19E03_31990	COG0444	Belongs to the ABC transporter superfamily
WP3W19E03_32000	COG4608	Belongs to the ABC transporter superfamily
WP3W19E03_32020	COG2971	BadF BadG BcrA BcrD
WP3W19E03_32070	COG3724	N-succinylarginine dihydrolase activity
WP3W19E03_32100	COG2197	response regulator
WP3W19E03_32110	COG5433	transposase activity
WP3W19E03_32170	COG2200	EAL domain
WP3W19E03_32170	COG2199	diguanylate cyclase activity
WP3W19E03_32170	COG2203	Gaf domain
WP3W19E03_32190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP3W19E03_32210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP3W19E03_32220	COG3706	GGDEF domain
WP3W19E03_32230	COG2211	Major facilitator Superfamily
WP3W19E03_32240	COG0616	signal peptide processing
WP3W19E03_32250	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_32260	COG0583	DNA-binding transcription factor activity
WP3W19E03_32280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP3W19E03_32370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WP3W19E03_32410	COG1301	dicarboxylic acid transport
WP3W19E03_32420	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WP3W19E03_32430	COG2912	Transglutaminase-like superfamily
WP3W19E03_32450	COG2890	protein-(glutamine-N5) methyltransferase activity
WP3W19E03_32460	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WP3W19E03_32470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WP3W19E03_32480	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WP3W19E03_32490	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WP3W19E03_32500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WP3W19E03_32510	COG0737	Belongs to the 5'-nucleotidase family
WP3W19E03_32520	COG0193	aminoacyl-tRNA hydrolase activity
WP3W19E03_32530	COG0012	GTP binding
WP3W19E03_32540	COG0490	domain, Protein
WP3W19E03_32540	COG0471	metal ion transport
WP3W19E03_32560	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
WP3W19E03_32600	COG0366	Alpha amylase catalytic
WP3W19E03_32620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP3W19E03_32650	COG1012	belongs to the aldehyde dehydrogenase family
WP3W19E03_32660	COG1012	belongs to the aldehyde dehydrogenase family
WP3W19E03_32680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WP3W19E03_32690	COG0512	Glutamine amidotransferase of anthranilate synthase
WP3W19E03_32710	COG0180	Tryptophanyl-tRNA synthetase
WP3W19E03_32730	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WP3W19E03_32740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WP3W19E03_32760	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WP3W19E03_32770	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WP3W19E03_32830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WP3W19E03_32840	COG0583	DNA-binding transcription factor activity
WP3W19E03_32880	COG0583	DNA-binding transcription factor activity
WP3W19E03_32900	COG0739	heme binding
WP3W19E03_32920	COG1511	domain protein
WP3W19E03_32920	COG3264	Mechanosensitive ion channel
WP3W19E03_32930	COG0584	glycerophosphoryl diester phosphodiesterase
WP3W19E03_32960	COG1053	succinate dehydrogenase
WP3W19E03_32970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WP3W19E03_32980	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WP3W19E03_32990	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WP3W19E03_33010	COG3214	Protein conserved in bacteria
WP3W19E03_33040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP3W19E03_33050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP3W19E03_33080	COG1022	Amp-dependent synthetase and ligase
WP3W19E03_33100	COG4221	oxidoreductase activity
WP3W19E03_33130	COG0642	Histidine kinase
WP3W19E03_33150	COG0516	GMP reductase activity
WP3W19E03_33170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WP3W19E03_33220	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
WP3W19E03_33230	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
WP3W19E03_33260	COG3385	transposase activity
WP3W19E03_33360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_33370	COG2204	response regulator
WP3W19E03_33390	COG0840	transmembrane signaling receptor activity
WP3W19E03_33400	COG0840	transmembrane signaling receptor activity
WP3W19E03_33420	COG2203	Gaf domain
WP3W19E03_33420	COG5001	Diguanylate cyclase
WP3W19E03_33420	COG4251	negative regulation of phosphorylation
WP3W19E03_33420	COG3706	GGDEF domain
WP3W19E03_33440	COG3706	GGDEF domain
WP3W19E03_33470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_33480	COG0753	catalase activity
WP3W19E03_33490	COG0583	DNA-binding transcription factor activity
WP3W19E03_33500	COG5433	transposase activity
WP3W19E03_33540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP3W19E03_33560	COG0783	Belongs to the Dps family
WP3W19E03_33590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WP3W19E03_33600	COG0183	Belongs to the thiolase family
WP3W19E03_33620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WP3W19E03_33630	COG0604	alcohol dehydrogenase
WP3W19E03_33650	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP3W19E03_33690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP3W19E03_33710	COG0519	Catalyzes the synthesis of GMP from XMP
WP3W19E03_33710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP3W19E03_33750	COG0625	glutathione transferase activity
WP3W19E03_33760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP3W19E03_33780	COG0583	DNA-binding transcription factor activity
WP3W19E03_33860	COG1846	Transcriptional regulator
WP3W19E03_33870	COG0583	DNA-binding transcription factor activity
WP3W19E03_33880	COG2948	multi-organism process
WP3W19E03_33920	COG1192	Involved in chromosome partitioning
WP3W19E03_33980	COG3385	transposase activity
WP3W19E03_34000	COG3647	Membrane
WP3W19E03_34020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP3W19E03_34040	COG0583	DNA-binding transcription factor activity
WP3W19E03_34050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
WP3W19E03_34070	COG3069	C4-dicarboxylate transmembrane transporter activity
WP3W19E03_34120	COG3706	GGDEF domain
WP3W19E03_34150	COG1335	isochorismatase
WP3W19E03_34160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP3W19E03_34170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP3W19E03_34180	COG1702	phosphate starvation-inducible protein PhoH
WP3W19E03_34190	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WP3W19E03_34200	COG4535	Mg2 and Co2 transporter CorC
WP3W19E03_34210	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WP3W19E03_34220	COG0789	Transcriptional regulator
WP3W19E03_34250	COG1970	mechanosensitive ion channel activity
WP3W19E03_34260	COG4974	Belongs to the 'phage' integrase family
WP3W19E03_34270	COG0716	FMN binding
WP3W19E03_34290	COG0312	modulator of DNA gyrase
WP3W19E03_34300	COG2888	peptidyl-tyrosine sulfation
WP3W19E03_34310	COG0495	leucyl-tRNA aminoacylation
WP3W19E03_34340	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WP3W19E03_34350	COG0799	negative regulation of ribosome biogenesis
WP3W19E03_34360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WP3W19E03_34370	COG0768	penicillin binding
WP3W19E03_34380	COG0772	Belongs to the SEDS family
WP3W19E03_34390	COG2951	lytic endotransglycosylase activity
WP3W19E03_34400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP3W19E03_34410	COG1686	Belongs to the peptidase S11 family
WP3W19E03_34420	COG2921	Belongs to the UPF0250 family
WP3W19E03_34430	COG0321	lipoyl(octanoyl) transferase activity
WP3W19E03_34450	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WP3W19E03_34490	COG3139	Protein of unknown function (DUF1315)
WP3W19E03_34500	COG0252	asparaginase activity
WP3W19E03_34510	COG0786	glutamate:sodium symporter activity
WP3W19E03_34530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WP3W19E03_34540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WP3W19E03_34550	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP3W19E03_34560	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP3W19E03_34570	COG0175	sulfate reduction
WP3W19E03_34580	COG2113	Glycine betaine
WP3W19E03_34590	COG4176	ABC-type proline glycine betaine transport system permease component
WP3W19E03_34600	COG4175	Glycine betaine
WP3W19E03_34630	COG2966	Psort location CytoplasmicMembrane, score
WP3W19E03_34650	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP3W19E03_34680	COG2897	thiosulfate sulfurtransferase activity
WP3W19E03_34690	COG2066	Belongs to the glutaminase family
WP3W19E03_34700	COG3171	Protein conserved in bacteria
WP3W19E03_34710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WP3W19E03_34720	COG2234	aminopeptidase activity
WP3W19E03_34720	COG4935	Belongs to the peptidase S8 family
WP3W19E03_34730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP3W19E03_34740	COG2200	EAL domain
WP3W19E03_34750	COG1090	epimerase
WP3W19E03_34760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WP3W19E03_34770	COG4181	ATPase activity
WP3W19E03_34780	COG2755	lipolytic protein G-D-S-L family
WP3W19E03_34790	COG0835	chemotaxis
WP3W19E03_34790	COG0784	Response regulator, receiver
WP3W19E03_34840	COG3397	chitin binding
WP3W19E03_34860	COG3706	GGDEF domain
WP3W19E03_34880	COG5002	protein histidine kinase activity
WP3W19E03_34880	COG2205	protein histidine kinase activity
WP3W19E03_34880	COG0784	Response regulator, receiver
WP3W19E03_34900	COG3655	Transcriptional regulator
WP3W19E03_34920	COG2814	Major facilitator Superfamily
WP3W19E03_34970	COG0748	coenzyme F420 binding
WP3W19E03_34980	COG3721	Heme iron utilization protein
WP3W19E03_35000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP3W19E03_35030	COG3275	phosphorelay sensor kinase activity
WP3W19E03_35040	COG3279	Response regulator of the LytR AlgR family
WP3W19E03_35050	COG1966	Carbon starvation protein
WP3W19E03_35060	COG3340	Belongs to the peptidase S51 family
WP3W19E03_35080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP3W19E03_35090	COG0305	Participates in initiation and elongation during chromosome replication
WP3W19E03_35120	COG1047	Peptidyl-prolyl cis-trans
WP3W19E03_35130	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WP3W19E03_35150	COG0835	chemotaxis
WP3W19E03_35150	COG0784	Response regulator, receiver
WP3W19E03_35160	COG0429	hydrolase of the alpha beta-hydrolase fold
WP3W19E03_35170	COG3706	GGDEF domain
WP3W19E03_35180	COG3089	Belongs to the UPF0270 family
WP3W19E03_35190	COG3954	Phosphoribulokinase
WP3W19E03_35220	COG1765	OsmC-like protein
WP3W19E03_35300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP3W19E03_35310	COG2313	pseudouridylate synthase activity
WP3W19E03_35340	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
WP3W19E03_35400	COG0569	domain protein
WP3W19E03_35400	COG2985	domain, Protein
WP3W19E03_35410	COG1272	protein, Hemolysin III
WP3W19E03_35420	COG0076	glutamate decarboxylase activity
WP3W19E03_35430	COG2917	probably involved in intracellular septation
WP3W19E03_35440	COG2350	Protein conserved in bacteria
WP3W19E03_35460	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WP3W19E03_35470	COG1381	Involved in DNA repair and RecF pathway recombination
WP3W19E03_35500	COG0681	Belongs to the peptidase S26 family
WP3W19E03_35510	COG0481	GTPase activity
WP3W19E03_35530	COG3026	antisigma factor binding
WP3W19E03_35540	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
WP3W19E03_35550	COG1595	DNA-templated transcription, initiation
WP3W19E03_35560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WP3W19E03_35580	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WP3W19E03_35590	COG0354	folic acid binding
WP3W19E03_35640	COG4232	protein-disulfide reductase activity
WP3W19E03_35680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP3W19E03_35690	COG0191	fructose-bisphosphate aldolase activity
WP3W19E03_35700	COG0126	phosphoglycerate kinase activity
WP3W19E03_35710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP3W19E03_35720	COG1940	carbohydrate kinase activity
WP3W19E03_35730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WP3W19E03_35740	COG2816	NAD+ diphosphatase activity
WP3W19E03_35760	COG4991	sh3 domain protein
WP3W19E03_35770	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP3W19E03_35800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WP3W19E03_35830	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_35860	COG2816	NAD+ diphosphatase activity
WP3W19E03_35910	COG1858	cytochrome C peroxidase
WP3W19E03_35920	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
WP3W19E03_35940	COG5001	Diguanylate cyclase
WP3W19E03_35950	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_36010	COG0154	amidase activity
WP3W19E03_36020	COG2957	Belongs to the agmatine deiminase family
WP3W19E03_36050	COG1902	pentaerythritol trinitrate reductase activity
WP3W19E03_36080	COG1238	metal cluster binding
WP3W19E03_36090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WP3W19E03_36100	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WP3W19E03_36110	COG0585	pseudouridine synthase activity
WP3W19E03_36130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WP3W19E03_36140	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WP3W19E03_36150	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP3W19E03_36170	COG1376	ErfK ybiS ycfS ynhG family protein
WP3W19E03_36180	COG0668	transmembrane transport
WP3W19E03_36200	COG2731	YhcH YjgK YiaL family protein
WP3W19E03_36220	COG1794	racemase activity, acting on amino acids and derivatives
WP3W19E03_36250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP3W19E03_36290	COG0488	(ABC) transporter
WP3W19E03_36310	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WP3W19E03_36390	COG0148	phosphopyruvate hydratase activity
WP3W19E03_36400	COG0504	CTP synthase activity
WP3W19E03_36410	COG3956	TIGRFAM MazG family protein
WP3W19E03_36420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP3W19E03_36430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP3W19E03_36450	COG4807	Protein conserved in bacteria
WP3W19E03_36460	COG3023	N-Acetylmuramoyl-L-alanine amidase
WP3W19E03_36470	COG0783	Belongs to the Dps family
WP3W19E03_36480	COG1151	hydroxylamine reductase activity
WP3W19E03_36490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP3W19E03_36500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP3W19E03_36510	COG0671	phosphoesterase, PA-phosphatase related
WP3W19E03_36520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP3W19E03_36530	COG0163	prenyltransferase activity
WP3W19E03_36560	COG1131	(ABC) transporter
WP3W19E03_36570	COG0842	Transport permease protein
WP3W19E03_36580	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
WP3W19E03_36590	COG1924	4 iron, 4 sulfur cluster binding
WP3W19E03_36620	COG1129	ABC transporter
WP3W19E03_36640	COG1486	melibiose metabolic process
WP3W19E03_36690	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WP3W19E03_36700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WP3W19E03_36710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WP3W19E03_36720	COG0617	tRNA 3'-terminal CCA addition
WP3W19E03_36730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP3W19E03_36740	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WP3W19E03_36750	COG1489	DNA binding
WP3W19E03_36770	COG1643	Atp-dependent helicase
WP3W19E03_36780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP3W19E03_36790	COG0346	lactoylglutathione lyase activity
WP3W19E03_36800	COG2076	Multidrug Resistance protein
WP3W19E03_36810	COG2076	Multidrug Resistance protein
WP3W19E03_36820	COG0583	DNA-binding transcription factor activity
WP3W19E03_36830	COG3437	response regulator, receiver
WP3W19E03_36830	COG0784	Response regulator, receiver
WP3W19E03_36840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WP3W19E03_36870	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WP3W19E03_36900	COG1136	(ABC) transporter
WP3W19E03_36940	COG0840	transmembrane signaling receptor activity
WP3W19E03_36960	COG3039	Transposase
WP3W19E03_36970	COG0529	Catalyzes the synthesis of activated sulfate
WP3W19E03_36980	COG0471	metal ion transport
WP3W19E03_36980	COG3273	potassium ion transport
WP3W19E03_36990	COG2895	sulfate adenylyltransferase (ATP) activity
WP3W19E03_37000	COG0175	sulfate reduction
WP3W19E03_37010	COG1648	precorrin-2 dehydrogenase activity
WP3W19E03_37010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP3W19E03_37020	COG0330	HflC and HflK could
WP3W19E03_37030	COG1585	Membrane protein implicated in regulation of membrane protease activity
WP3W19E03_37040	COG0840	transmembrane signaling receptor activity
WP3W19E03_37050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WP3W19E03_37060	COG0676	glucose-6-phosphate 1-epimerase activity
WP3W19E03_37070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP3W19E03_37080	COG1640	4-alpha-glucanotransferase
WP3W19E03_37090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WP3W19E03_37190	COG0561	phosphatase activity
WP3W19E03_37220	COG0733	neurotransmitter:sodium symporter activity
WP3W19E03_37260	COG0733	neurotransmitter:sodium symporter activity
WP3W19E03_37270	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WP3W19E03_37280	COG2885	chlorophyll binding
WP3W19E03_37290	COG0823	Involved in the tonB-independent uptake of proteins
WP3W19E03_37320	COG0811	peptide transport
WP3W19E03_37330	COG0824	Thioesterase
WP3W19E03_37340	COG3790	cyd operon protein YbgE
WP3W19E03_37350	COG4890	Cyd operon protein YbgT
WP3W19E03_37360	COG1294	oxidase, subunit
WP3W19E03_37380	COG2255	four-way junction helicase activity
WP3W19E03_37390	COG0632	four-way junction helicase activity
WP3W19E03_37430	COG2771	luxR family
WP3W19E03_37440	COG3916	Acyl-homoserine-lactone synthase
WP3W19E03_37460	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
WP3W19E03_37470	COG2203	Gaf domain
WP3W19E03_37470	COG3706	GGDEF domain
WP3W19E03_37470	COG4251	negative regulation of phosphorylation
WP3W19E03_37470	COG5001	Diguanylate cyclase
WP3W19E03_37490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP3W19E03_37510	COG2995	paraquat-inducible protein a
WP3W19E03_37520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP3W19E03_37520	COG3008	intermembrane lipid transfer
WP3W19E03_37540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP3W19E03_37550	COG0442	prolyl-tRNA aminoacylation
WP3W19E03_37560	COG4221	oxidoreductase activity
WP3W19E03_37590	COG1024	Enoyl-CoA hydratase
WP3W19E03_37610	COG0110	maltose O-acetyltransferase activity
WP3W19E03_37630	COG4166	transmembrane transport
WP3W19E03_37650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP3W19E03_37680	COG3385	transposase activity
WP3W19E03_37690	COG3039	Transposase
WP3W19E03_37700	COG0735	belongs to the Fur family
WP3W19E03_37750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WP3W19E03_37760	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_37770	COG2153	protein acetylation
WP3W19E03_37790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP3W19E03_37800	COG0557	exoribonuclease II activity
WP3W19E03_37810	COG3706	GGDEF domain
WP3W19E03_37830	COG3240	lipase activity
WP3W19E03_37840	COG3111	PFAM Bacterial OB fold (BOF) protein
WP3W19E03_37860	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WP3W19E03_37870	COG1194	a g-specific adenine glycosylase
WP3W19E03_37880	COG0617	tRNA 3'-terminal CCA addition
WP3W19E03_37920	COG3068	Protein conserved in bacteria
WP3W19E03_37940	COG0739	heme binding
WP3W19E03_38000	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WP3W19E03_38010	COG1121	(ABC) transporter
WP3W19E03_38020	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WP3W19E03_38030	COG0583	DNA-binding transcription factor activity
WP3W19E03_38050	COG1573	uracil-dna glycosylase
WP3W19E03_38080	COG2827	Endonuclease containing a URI domain
WP3W19E03_38110	COG1842	Phage shock protein A
WP3W19E03_38120	COG0204	Acyl-transferase
WP3W19E03_38160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP3W19E03_38170	COG0484	heat shock protein binding
WP3W19E03_38210	COG3104	oligopeptide transport
WP3W19E03_38270	COG3150	esterase
WP3W19E03_38290	COG3151	Protein conserved in bacteria
WP3W19E03_38300	COG0494	nUDIX hydrolase
WP3W19E03_38310	COG1538	Outer membrane efflux protein
WP3W19E03_38320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WP3W19E03_38320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WP3W19E03_38330	COG1560	Kdo2-lipid A biosynthetic process
WP3W19E03_38340	COG2213	PTS system mannitol-specific
WP3W19E03_38340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_38350	COG0246	Mannitol dehydrogenase
WP3W19E03_38360	COG3722	fumarate hydratase activity
WP3W19E03_38410	COG1671	Belongs to the UPF0178 family
WP3W19E03_38420	COG1988	membrane-bound metal-dependent
WP3W19E03_38430	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP3W19E03_38440	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_38480	COG1575	Belongs to the MenA family. Type 1 subfamily
WP3W19E03_38490	COG1169	isochorismate synthase
WP3W19E03_38500	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WP3W19E03_38510	COG0596	Alpha beta hydrolase
WP3W19E03_38520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WP3W19E03_38530	COG1441	menaquinone biosynthetic process
WP3W19E03_38540	COG0318	PFAM AMP-dependent synthetase and ligase
WP3W19E03_38550	COG3291	Pkd domain containing protein
WP3W19E03_38560	COG2949	membrane
WP3W19E03_38570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WP3W19E03_38590	COG0784	Response regulator, receiver
WP3W19E03_38590	COG0835	chemotaxis
WP3W19E03_38600	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_38610	COG1444	tRNA N-acetyltransferase activity
WP3W19E03_38660	COG1803	Methylglyoxal synthase
WP3W19E03_38670	COG1979	alcohol dehydrogenase
WP3W19E03_38710	COG4221	oxidoreductase activity
WP3W19E03_38780	COG1368	sulfuric ester hydrolase activity
WP3W19E03_38790	COG1522	sequence-specific DNA binding
WP3W19E03_38810	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
WP3W19E03_38830	COG1058	Belongs to the CinA family
WP3W19E03_38830	COG1546	Belongs to the CinA family
WP3W19E03_38850	COG0561	phosphatase activity
WP3W19E03_38870	COG2926	Belongs to the UPF0265 family
WP3W19E03_38890	COG1396	sequence-specific DNA binding
WP3W19E03_38900	COG3135	benzoate transporter
WP3W19E03_38960	COG0840	transmembrane signaling receptor activity
WP3W19E03_38970	COG3047	cAMP biosynthetic process
WP3W19E03_38980	COG3706	GGDEF domain
WP3W19E03_38990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WP3W19E03_39040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WP3W19E03_39060	COG1278	Cold shock
WP3W19E03_39070	COG2252	PERMEase
WP3W19E03_39080	COG2376	Dihydroxyacetone kinase
WP3W19E03_39090	COG1461	Dihydroxyacetone kinase
WP3W19E03_39100	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
WP3W19E03_39100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_39100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP3W19E03_39120	COG3284	Transcriptional regulator
WP3W19E03_39140	COG5433	transposase activity
WP3W19E03_39180	COG0583	DNA-binding transcription factor activity
WP3W19E03_39190	COG2957	Belongs to the agmatine deiminase family
WP3W19E03_39210	COG0628	permease
WP3W19E03_39220	COG0494	nUDIX hydrolase
WP3W19E03_39250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WP3W19E03_39300	COG0456	acetyltransferase
WP3W19E03_39310	COG3133	Outer membrane lipoprotein
WP3W19E03_39320	COG0004	ammonium transporteR
WP3W19E03_39330	COG3706	GGDEF domain
WP3W19E03_39350	COG3932	Exopolysaccharide synthesis, ExoD
WP3W19E03_39360	COG0814	amino acid
WP3W19E03_39390	COG0110	maltose O-acetyltransferase activity
WP3W19E03_39400	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WP3W19E03_39420	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WP3W19E03_39430	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP3W19E03_39450	COG0137	argininosuccinate synthase activity
WP3W19E03_39460	COG0165	Argininosuccinate lyase
WP3W19E03_39530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WP3W19E03_39540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WP3W19E03_39570	COG0477	Major facilitator Superfamily
WP3W19E03_39580	COG0523	cobalamin synthesis protein
WP3W19E03_39600	COG1280	lysine exporter protein (LysE YggA)
WP3W19E03_39630	COG1028	Short-chain dehydrogenase reductase Sdr
WP3W19E03_39640	COG2200	EAL domain
WP3W19E03_39660	COG1049	propionate catabolic process, 2-methylcitrate cycle
WP3W19E03_39670	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP3W19E03_39680	COG0840	transmembrane signaling receptor activity
WP3W19E03_39700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP3W19E03_39710	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP3W19E03_39720	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WP3W19E03_39730	COG2186	Transcriptional regulator
WP3W19E03_39770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP3W19E03_39780	COG1459	type II secretion system
WP3W19E03_39810	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WP3W19E03_39820	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WP3W19E03_39830	COG0494	nUDIX hydrolase
WP3W19E03_39840	COG0653	protein targeting
WP3W19E03_39860	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WP3W19E03_39870	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WP3W19E03_39880	COG0849	cell division
WP3W19E03_39900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP3W19E03_39910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WP3W19E03_39920	COG0772	Belongs to the SEDS family
WP3W19E03_39940	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WP3W19E03_39950	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WP3W19E03_39960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WP3W19E03_39980	COG0768	penicillin binding
WP3W19E03_39990	COG3116	cell division
WP3W19E03_40000	COG0275	rRNA processing
WP3W19E03_40010	COG2001	Belongs to the MraZ family
WP3W19E03_40050	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WP3W19E03_40060	COG3107	peptidoglycan biosynthetic process
WP3W19E03_40070	COG0792	nuclease activity
WP3W19E03_40080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP3W19E03_40100	COG2969	positive regulation of protein catabolic process
WP3W19E03_40110	COG0625	glutathione transferase activity
WP3W19E03_40120	COG2857	Cytochrome c1
WP3W19E03_40130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WP3W19E03_40140	COG0723	plastoquinol--plastocyanin reductase activity
WP3W19E03_40150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WP3W19E03_40160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WP3W19E03_40170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WP3W19E03_40190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP3W19E03_40200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP3W19E03_40210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_40220	COG1660	Displays ATPase and GTPase activities
WP3W19E03_40230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP3W19E03_40260	COG1137	ATPase activity
WP3W19E03_40270	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WP3W19E03_40280	COG3117	lipopolysaccharide transmembrane transporter activity
WP3W19E03_40290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WP3W19E03_40300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WP3W19E03_40300	COG0517	IMP dehydrogenase activity
WP3W19E03_40310	COG1127	ABC transporter
WP3W19E03_40320	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WP3W19E03_40330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP3W19E03_40340	COG2854	intermembrane phospholipid transfer
WP3W19E03_40360	COG5007	Belongs to the BolA IbaG family
WP3W19E03_40370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WP3W19E03_40380	COG0312	modulator of DNA gyrase
WP3W19E03_40390	COG3028	Belongs to the UPF0307 family
WP3W19E03_40400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WP3W19E03_40420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP3W19E03_40440	COG1011	Hydrolase
WP3W19E03_40470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WP3W19E03_40480	COG0019	diaminopimelate decarboxylase activity
WP3W19E03_40490	COG1965	Belongs to the frataxin family
WP3W19E03_40500	COG0400	carboxylic ester hydrolase activity
WP3W19E03_40510	COG3072	Adenylate cyclase
WP3W19E03_40520	COG0181	hydroxymethylbilane synthase activity
WP3W19E03_40540	COG2959	enzyme of heme biosynthesis
WP3W19E03_40570	COG1494	fructose-1,6-bisphosphatase
WP3W19E03_40680	COG0795	lipopolysaccharide-transporting ATPase activity
WP3W19E03_40700	COG0795	lipopolysaccharide-transporting ATPase activity
WP3W19E03_40710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP3W19E03_40720	COG2927	DNA polymerase III (CHI subunit)
WP3W19E03_40770	COG0456	acetyltransferase
WP3W19E03_40770	COG0454	-acetyltransferase
WP3W19E03_40780	COG0753	catalase activity
WP3W19E03_40830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP3W19E03_40840	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
WP3W19E03_40850	COG5380	lipid catabolic process
WP3W19E03_40890	COG4533	DNA binding
WP3W19E03_40910	COG2873	o-acetylhomoserine
WP3W19E03_40920	COG3385	transposase activity
WP3W19E03_40980	COG3842	ATPase activity
WP3W19E03_41000	COG1175	transmembrane transport
WP3W19E03_41070	COG5433	transposase activity
WP3W19E03_41100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP3W19E03_41110	COG1074	ATP-dependent DNA helicase activity
WP3W19E03_41120	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WP3W19E03_41130	COG2259	Doxx family
WP3W19E03_41140	COG1741	Belongs to the pirin family
WP3W19E03_41160	COG0583	DNA-binding transcription factor activity
WP3W19E03_41200	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_41220	COG3706	GGDEF domain
WP3W19E03_41230	COG4771	TonB-dependent receptor
WP3W19E03_41250	COG0203	ribosomal protein L17
WP3W19E03_41260	COG0202	RNA polymerase activity
WP3W19E03_41270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WP3W19E03_41280	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WP3W19E03_41290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WP3W19E03_41300	COG0201	protein transport
WP3W19E03_41310	COG0200	Binds to the 23S rRNA
WP3W19E03_41320	COG1841	ribosomal large subunit assembly
WP3W19E03_41330	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WP3W19E03_41340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WP3W19E03_41350	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WP3W19E03_41360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WP3W19E03_41370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WP3W19E03_41380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WP3W19E03_41390	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WP3W19E03_41400	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WP3W19E03_41410	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WP3W19E03_41420	COG0255	Belongs to the universal ribosomal protein uL29 family
WP3W19E03_41430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WP3W19E03_41440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WP3W19E03_41450	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WP3W19E03_41460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WP3W19E03_41470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WP3W19E03_41480	COG0089	rRNA binding
WP3W19E03_41490	COG0088	Forms part of the polypeptide exit tunnel
WP3W19E03_41500	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WP3W19E03_41510	COG0051	transcription antitermination factor activity, RNA binding
WP3W19E03_41540	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_41550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP3W19E03_41560	COG2183	response to ionizing radiation
WP3W19E03_41600	COG0596	Alpha beta hydrolase
WP3W19E03_41610	COG1040	competence protein
WP3W19E03_41620	COG0316	Belongs to the HesB IscA family
WP3W19E03_41620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WP3W19E03_41630	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WP3W19E03_41640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WP3W19E03_41650	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP3W19E03_41660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WP3W19E03_41670	COG4942	peptidase
WP3W19E03_41690	COG1609	Transcriptional regulator
WP3W19E03_41700	COG0800	Aldolase
WP3W19E03_41710	COG0129	dihydroxy-acid dehydratase activity
WP3W19E03_41720	COG3265	gluconokinase activity
WP3W19E03_41730	COG2610	gluconate transmembrane transporter activity
WP3W19E03_41740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP3W19E03_41750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WP3W19E03_41770	COG0456	acetyltransferase
WP3W19E03_41790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WP3W19E03_41800	COG1490	D-aminoacyl-tRNA deacylase activity
WP3W19E03_41810	COG1295	ribonuclease BN
WP3W19E03_41820	COG0281	malic enzyme
WP3W19E03_41830	COG0814	amino acid
WP3W19E03_41840	COG0702	epimerase
WP3W19E03_41860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WP3W19E03_41870	COG0254	rRNA binding
WP3W19E03_41900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP3W19E03_41910	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WP3W19E03_41930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WP3W19E03_41950	COG0514	ATP-dependent DNA helicase (RecQ)
WP3W19E03_41960	COG2050	protein possibly involved in aromatic compounds catabolism
WP3W19E03_41980	COG2258	MOSC domain
WP3W19E03_41990	COG1177	transmembrane transport
WP3W19E03_42000	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP3W19E03_42010	COG3842	ATPase activity
WP3W19E03_42050	COG0174	glutamine synthetase
WP3W19E03_42090	COG3045	CreA protein
WP3W19E03_42100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP3W19E03_42120	COG0443	Heat shock 70 kDa protein
WP3W19E03_42150	COG0366	Alpha amylase catalytic
WP3W19E03_42160	COG3385	transposase activity
WP3W19E03_42190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP3W19E03_42210	COG4211	Belongs to the binding-protein-dependent transport system permease family
WP3W19E03_42240	COG3250	beta-galactosidase activity
WP3W19E03_42250	COG1609	Transcriptional regulator
WP3W19E03_42260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP3W19E03_42280	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WP3W19E03_42290	COG2017	converts alpha-aldose to the beta-anomer
WP3W19E03_42300	COG1968	undecaprenyl-diphosphatase activity
WP3W19E03_42320	COG1595	DNA-templated transcription, initiation
WP3W19E03_42340	COG0018	arginyl-trna synthetase
WP3W19E03_42360	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WP3W19E03_42370	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WP3W19E03_42390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP3W19E03_42400	COG1131	(ABC) transporter
WP3W19E03_42410	COG0842	Transport permease protein
WP3W19E03_42420	COG0842	Transport permease protein
WP3W19E03_42430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP3W19E03_42450	COG2116	formate transmembrane transporter activity
WP3W19E03_42460	COG1648	precorrin-2 dehydrogenase activity
WP3W19E03_42460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP3W19E03_42470	COG2239	Acts as a magnesium transporter
WP3W19E03_42530	COG0210	DNA helicase
WP3W19E03_42540	COG0210	DNA helicase
WP3W19E03_42560	COG1943	Transposase
WP3W19E03_42660	COG1280	lysine exporter protein (LysE YggA)
WP3W19E03_42740	COG3306	glycosyltransferase involved in LPS biosynthesis
WP3W19E03_42750	COG3307	-O-antigen
WP3W19E03_42780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP3W19E03_42810	COG1063	alcohol dehydrogenase
WP3W19E03_42820	COG3245	cytochrome
WP3W19E03_42850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WP3W19E03_42860	COG2166	iron-sulfur cluster assembly
WP3W19E03_42870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WP3W19E03_42890	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
WP3W19E03_42900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP3W19E03_42910	COG1739	Uncharacterized protein family UPF0029
WP3W19E03_42920	COG0006	proline dipeptidase activity
WP3W19E03_42930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP3W19E03_42940	COG1024	Enoyl-CoA hydratase
WP3W19E03_42940	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP3W19E03_42950	COG0183	Belongs to the thiolase family
WP3W19E03_42960	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_42970	COG2205	protein histidine kinase activity
WP3W19E03_43000	COG0425	Belongs to the sulfur carrier protein TusA family
WP3W19E03_43010	COG0251	oxidation-reduction process
WP3W19E03_43020	COG2885	chlorophyll binding
WP3W19E03_43050	COG2818	Glycosylase
WP3W19E03_43060	COG0752	glycyl-tRNA synthetase alpha subunit
WP3W19E03_43070	COG0751	glycine-tRNA ligase activity
WP3W19E03_43150	COG1609	Transcriptional regulator
WP3W19E03_43210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP3W19E03_43240	COG2960	long-chain fatty acid transporting porin activity
WP3W19E03_43250	COG5001	Diguanylate cyclase
WP3W19E03_43270	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WP3W19E03_43300	COG3118	belongs to the thioredoxin family
WP3W19E03_43310	COG0513	Belongs to the DEAD box helicase family
WP3W19E03_43320	COG0248	Ppx GppA phosphatase
WP3W19E03_43340	COG0742	ribosomal rna small subunit methyltransferase
WP3W19E03_43360	COG3385	transposase activity
WP3W19E03_43380	COG3469	chitinase activity
WP3W19E03_43400	COG0084	hydrolase, TatD family'
WP3W19E03_43410	COG0805	protein transport
WP3W19E03_43420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP3W19E03_43430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP3W19E03_43440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WP3W19E03_43450	COG3165	ubiquinone biosynthetic process from chorismate
WP3W19E03_43460	COG2226	methyltransferase
WP3W19E03_43470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WP3W19E03_43480	COG0402	S-adenosylhomocysteine deaminase activity
WP3W19E03_43490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WP3W19E03_43520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
WP3W19E03_43530	COG0848	biopolymer transport protein
WP3W19E03_43540	COG0811	peptide transport
WP3W19E03_43550	COG0811	peptide transport
WP3W19E03_43570	COG2771	luxR family
WP3W19E03_43590	COG1111	helicase
WP3W19E03_43590	COG1205	dead DEAH box helicase
WP3W19E03_43850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WP3W19E03_43860	COG1349	DNA-binding transcription factor activity
WP3W19E03_43870	COG0745	RESPONSE REGULATOR receiver
WP3W19E03_43880	COG2205	protein histidine kinase activity
WP3W19E03_43910	COG4452	Inner membrane protein CreD
WP3W19E03_43920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WP3W19E03_43930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WP3W19E03_43940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WP3W19E03_43950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WP3W19E03_43960	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WP3W19E03_43970	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WP3W19E03_43980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WP3W19E03_44000	COG0356	it plays a direct role in the translocation of protons across the membrane
WP3W19E03_44020	COG1475	DNA binding
WP3W19E03_44030	COG1192	Involved in chromosome partitioning
WP3W19E03_44040	COG0357	Ribosomal RNA small subunit methyltransferase G
WP3W19E03_44050	COG0445	tRNA wobble uridine modification
WP3W19E03_44060	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP3W19E03_44070	COG4774	siderophore transport
WP3W19E03_44080	COG4615	Cyclic peptide transporter
WP3W19E03_44090	COG1120	ATPase activity
WP3W19E03_44100	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WP3W19E03_44110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP3W19E03_44120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WP3W19E03_44130	COG0706	membrane insertase activity
WP3W19E03_44140	COG0594	ribonuclease P activity
WP3W19E03_44150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WP3W19E03_P10040	COG3077	Addiction module antitoxin, RelB DinJ family
WP3W19E03_P10050	COG2026	Addiction module toxin, RelE StbE family