locus-tag	class	description
WP9W18E04_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WP9W18E04_00020	COG0592	DNA-directed DNA polymerase activity
WP9W18E04_00040	COG0187	DNA topoisomerase II activity
WP9W18E04_00070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WP9W18E04_00080	COG0071	Belongs to the small heat shock protein (HSP20) family
WP9W18E04_00090	COG0071	Belongs to the small heat shock protein (HSP20) family
WP9W18E04_00100	COG3977	Valine--pyruvate aminotransferase
WP9W18E04_00130	COG2814	Major facilitator Superfamily
WP9W18E04_00140	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_00150	COG2205	protein histidine kinase activity
WP9W18E04_00190	COG1733	regulation of RNA biosynthetic process
WP9W18E04_00200	COG2267	carboxylic ester hydrolase activity
WP9W18E04_00210	COG0604	alcohol dehydrogenase
WP9W18E04_00230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP9W18E04_00240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_00240	COG4191	Histidine kinase
WP9W18E04_00250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP9W18E04_00260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_00270	COG1309	transcriptional regulator
WP9W18E04_00290	COG0469	pyruvate kinase activity
WP9W18E04_00300	COG2271	Major facilitator Superfamily
WP9W18E04_00360	COG0561	phosphatase activity
WP9W18E04_00370	COG2267	carboxylic ester hydrolase activity
WP9W18E04_00390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP9W18E04_00400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP9W18E04_00410	COG1758	RNA polymerase activity
WP9W18E04_00420	COG0194	GDP metabolic process
WP9W18E04_00430	COG0859	PFAM glycosyl transferase family 9
WP9W18E04_00440	COG3642	lipopolysaccharide core region biosynthetic process
WP9W18E04_00520	COG0589	response to stress
WP9W18E04_00530	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP9W18E04_00540	COG1528	Iron-storage protein
WP9W18E04_00550	COG2081	HI0933 family
WP9W18E04_00560	COG3275	phosphorelay sensor kinase activity
WP9W18E04_00580	COG3279	Response regulator of the LytR AlgR family
WP9W18E04_00590	COG2223	nitrite transmembrane transporter activity
WP9W18E04_00600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WP9W18E04_00610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WP9W18E04_00640	COG0583	DNA-binding transcription factor activity
WP9W18E04_00690	COG3318	Belongs to the UPF0149 family
WP9W18E04_00690	COG3012	SEC-C Motif Domain Protein
WP9W18E04_00730	COG4584	PFAM Integrase catalytic
WP9W18E04_00740	COG1484	DNA-dependent DNA replication
WP9W18E04_00890	COG2003	Belongs to the UPF0758 family
WP9W18E04_01000	COG4983	Phage plasmid primase, P4 family domain protein
WP9W18E04_01030	COG1484	DNA-dependent DNA replication
WP9W18E04_01040	COG4584	PFAM Integrase catalytic
WP9W18E04_01050	COG3039	Transposase
WP9W18E04_01060	COG0582	viral genome integration into host DNA
WP9W18E04_01070	COG1042	CoA-binding domain protein
WP9W18E04_01070	COG0045	succinate-CoA ligase (ADP-forming) activity
WP9W18E04_01070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP9W18E04_01110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WP9W18E04_01120	COG0166	Belongs to the GPI family
WP9W18E04_01130	COG0668	transmembrane transport
WP9W18E04_01140	COG1309	transcriptional regulator
WP9W18E04_01150	COG0756	dUTP diphosphatase activity
WP9W18E04_01160	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WP9W18E04_01170	COG2003	Belongs to the UPF0758 family
WP9W18E04_01180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WP9W18E04_01190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WP9W18E04_01210	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WP9W18E04_01220	COG2990	Protein conserved in bacteria
WP9W18E04_01230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WP9W18E04_01240	COG0859	PFAM glycosyl transferase family 9
WP9W18E04_01250	COG0463	Glycosyl transferase, family 2
WP9W18E04_01260	COG0859	PFAM glycosyl transferase family 9
WP9W18E04_01270	COG1519	Transferase
WP9W18E04_01300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_01310	COG1609	Transcriptional regulator
WP9W18E04_01320	COG0604	alcohol dehydrogenase
WP9W18E04_01370	COG3161	chorismate lyase activity
WP9W18E04_01380	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WP9W18E04_01390	COG2937	Belongs to the GPAT DAPAT family
WP9W18E04_01400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WP9W18E04_01430	COG0534	Mate efflux family protein
WP9W18E04_01440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WP9W18E04_01450	COG2205	protein histidine kinase activity
WP9W18E04_01460	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_01480	COG1045	serine acetyltransferase
WP9W18E04_01500	COG3074	FtsZ-dependent cytokinesis
WP9W18E04_01510	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WP9W18E04_01520	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP9W18E04_01520	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP9W18E04_01530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WP9W18E04_01540	COG1609	Transcriptional regulator
WP9W18E04_01550	COG3250	beta-galactosidase activity
WP9W18E04_01560	COG2731	YhcH YjgK YiaL family protein
WP9W18E04_01570	COG0531	amino acid
WP9W18E04_01580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP9W18E04_01590	COG0531	amino acid
WP9W18E04_01600	COG3385	transposase activity
WP9W18E04_01610	COG0385	Bile acid
WP9W18E04_01620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
WP9W18E04_01660	COG0583	DNA-binding transcription factor activity
WP9W18E04_01670	COG1561	YicC-like family, N-terminal region
WP9W18E04_01690	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WP9W18E04_01720	COG2203	Gaf domain
WP9W18E04_01720	COG4251	negative regulation of phosphorylation
WP9W18E04_01720	COG3706	GGDEF domain
WP9W18E04_01720	COG5001	Diguanylate cyclase
WP9W18E04_01730	COG3084	Protein conserved in bacteria
WP9W18E04_01750	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WP9W18E04_01760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP9W18E04_01780	COG1335	isochorismatase
WP9W18E04_01800	COG1683	Conserved Protein
WP9W18E04_01810	COG0204	Acyl-transferase
WP9W18E04_01820	COG0204	Acyl-transferase
WP9W18E04_01830	COG0606	chelatase, subunit chli
WP9W18E04_01850	COG3978	acetolactate synthase activity
WP9W18E04_01870	COG0129	dihydroxy-acid dehydratase activity
WP9W18E04_01900	COG2391	methyltransferase activity
WP9W18E04_01910	COG0840	transmembrane signaling receptor activity
WP9W18E04_01920	COG2962	Rard protein
WP9W18E04_01940	COG1012	belongs to the aldehyde dehydrogenase family
WP9W18E04_01950	COG1396	sequence-specific DNA binding
WP9W18E04_01980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP9W18E04_01980	COG0519	Catalyzes the synthesis of GMP from XMP
WP9W18E04_01990	COG0583	DNA-binding transcription factor activity
WP9W18E04_02000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP9W18E04_02050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WP9W18E04_02060	COG2204	response regulator
WP9W18E04_02090	COG0174	glutamine synthetase
WP9W18E04_02110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP9W18E04_02120	COG0569	domain protein
WP9W18E04_02130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP9W18E04_02130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP9W18E04_02140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WP9W18E04_02150	COG0242	peptide deformylase activity
WP9W18E04_02160	COG1652	LysM domain
WP9W18E04_02170	COG0758	DNA mediated transformation
WP9W18E04_02180	COG2922	Belongs to the Smg family
WP9W18E04_02190	COG0551	DNA topoisomerase type I activity
WP9W18E04_02210	COG0009	L-threonylcarbamoyladenylate synthase
WP9W18E04_02220	COG0408	coproporphyrinogen oxidase activity
WP9W18E04_02230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WP9W18E04_02250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WP9W18E04_02270	COG3078	GTPase activator activity
WP9W18E04_02350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP9W18E04_02360	COG1288	antiporter activity
WP9W18E04_02370	COG1438	arginine binding
WP9W18E04_02380	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
WP9W18E04_02390	COG0540	Belongs to the ATCase OTCase family
WP9W18E04_02430	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
WP9W18E04_02460	COG3040	lipid binding
WP9W18E04_02470	COG2207	Transcriptional regulator
WP9W18E04_02480	COG1979	alcohol dehydrogenase
WP9W18E04_02490	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WP9W18E04_02500	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WP9W18E04_02510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_02520	COG2964	Protein conserved in bacteria
WP9W18E04_02530	COG3681	Belongs to the UPF0597 family
WP9W18E04_02550	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP9W18E04_02560	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP9W18E04_02570	COG0564	pseudouridine synthase activity
WP9W18E04_02590	COG0542	response to heat
WP9W18E04_02600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WP9W18E04_02610	COG2502	aspartate--ammonia ligase
WP9W18E04_02620	COG1522	sequence-specific DNA binding
WP9W18E04_02640	COG5413	integral membrane protein
WP9W18E04_02650	COG0517	IMP dehydrogenase activity
WP9W18E04_02650	COG0516	GMP reductase activity
WP9W18E04_02670	COG1028	Short-chain dehydrogenase reductase Sdr
WP9W18E04_02700	COG2205	protein histidine kinase activity
WP9W18E04_02720	COG2204	response regulator
WP9W18E04_02790	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_02800	COG2205	protein histidine kinase activity
WP9W18E04_02820	COG0243	molybdopterin cofactor binding
WP9W18E04_02830	COG3005	denitrification pathway
WP9W18E04_02840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_02840	COG4191	Histidine kinase
WP9W18E04_02900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP9W18E04_02910	COG0569	domain protein
WP9W18E04_02920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WP9W18E04_02950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP9W18E04_02970	COG0250	Participates in transcription elongation, termination and antitermination
WP9W18E04_02980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WP9W18E04_02990	COG0081	regulation of translation
WP9W18E04_03000	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WP9W18E04_03010	COG0222	ribosome binding
WP9W18E04_03020	COG0085	RNA polymerase activity
WP9W18E04_03030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WP9W18E04_03040	COG2964	Protein conserved in bacteria
WP9W18E04_03060	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP9W18E04_03070	COG2923	Belongs to the DsrF TusC family
WP9W18E04_03080	COG2168	tRNA wobble position uridine thiolation
WP9W18E04_03090	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
WP9W18E04_03100	COG0049	tRNA binding
WP9W18E04_03110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WP9W18E04_03120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WP9W18E04_03130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP9W18E04_03180	COG3714	YhhN family
WP9W18E04_03230	COG1301	dicarboxylic acid transport
WP9W18E04_03250	COG2095	MarC family integral membrane protein
WP9W18E04_03290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP9W18E04_03310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP9W18E04_03340	COG1770	oligopeptidase
WP9W18E04_03370	COG4221	oxidoreductase activity
WP9W18E04_03380	COG0583	DNA-binding transcription factor activity
WP9W18E04_03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
WP9W18E04_03440	COG0742	ribosomal rna small subunit methyltransferase
WP9W18E04_03450	COG0552	protein localization to endoplasmic reticulum
WP9W18E04_03460	COG2884	Cell division ATP-binding protein ftsE
WP9W18E04_03470	COG2177	Part of the ABC transporter FtsEX involved in
WP9W18E04_03490	COG0288	reversible hydration of carbon dioxide
WP9W18E04_03500	COG2188	Transcriptional regulator
WP9W18E04_03510	COG1228	amidohydrolase
WP9W18E04_03520	COG0010	Belongs to the arginase family
WP9W18E04_03530	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WP9W18E04_03540	COG2986	histidine ammonia-lyase
WP9W18E04_03550	COG0387	Pfam Sodium calcium exchanger
WP9W18E04_03560	COG2200	EAL domain
WP9W18E04_03570	COG2200	EAL domain
WP9W18E04_03570	COG2199	diguanylate cyclase activity
WP9W18E04_03660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP9W18E04_03670	COG1459	type II secretion system
WP9W18E04_03700	COG4969	Belongs to the N-Me-Phe pilin family
WP9W18E04_03710	COG4968	Prepilin-type N-terminal cleavage methylation domain
WP9W18E04_03760	COG1077	Cell shape determining protein MreB Mrl
WP9W18E04_03770	COG1792	Involved in formation and maintenance of cell shape
WP9W18E04_03780	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WP9W18E04_03790	COG0424	maF-like protein
WP9W18E04_03800	COG1530	ribonuclease E activity
WP9W18E04_03810	COG3164	Protein of unknown function
WP9W18E04_03830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP9W18E04_03840	COG0312	modulator of DNA gyrase
WP9W18E04_03880	COG0477	Major facilitator Superfamily
WP9W18E04_03970	COG0189	ligase activity
WP9W18E04_03980	COG0642	Histidine kinase
WP9W18E04_03990	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_04020	COG0789	Transcriptional regulator
WP9W18E04_04030	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WP9W18E04_04040	COG0352	thiamine-phosphate diphosphorylase activity
WP9W18E04_04050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP9W18E04_04070	COG2022	thiamine diphosphate biosynthetic process
WP9W18E04_04080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP9W18E04_04160	COG0110	maltose O-acetyltransferase activity
WP9W18E04_04200	COG0814	amino acid
WP9W18E04_04210	COG3932	Exopolysaccharide synthesis, ExoD
WP9W18E04_04230	COG3706	GGDEF domain
WP9W18E04_04240	COG0004	ammonium transporteR
WP9W18E04_04250	COG3133	Outer membrane lipoprotein
WP9W18E04_04260	COG0456	acetyltransferase
WP9W18E04_04310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WP9W18E04_04340	COG0494	nUDIX hydrolase
WP9W18E04_04350	COG0628	permease
WP9W18E04_04380	COG2957	Belongs to the agmatine deiminase family
WP9W18E04_04390	COG0583	DNA-binding transcription factor activity
WP9W18E04_04400	COG3284	Transcriptional regulator
WP9W18E04_04430	COG1461	Dihydroxyacetone kinase
WP9W18E04_04440	COG2376	Dihydroxyacetone kinase
WP9W18E04_04460	COG2252	PERMEase
WP9W18E04_04470	COG1278	Cold shock
WP9W18E04_04490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WP9W18E04_04590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP9W18E04_04650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WP9W18E04_04660	COG3706	GGDEF domain
WP9W18E04_04670	COG3047	cAMP biosynthetic process
WP9W18E04_04680	COG0840	transmembrane signaling receptor activity
WP9W18E04_04730	COG3135	benzoate transporter
WP9W18E04_04740	COG1396	sequence-specific DNA binding
WP9W18E04_04770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WP9W18E04_04770	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP9W18E04_04800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WP9W18E04_04810	COG0038	chloride channel
WP9W18E04_04830	COG0316	Belongs to the HesB IscA family
WP9W18E04_04840	COG1757	Na H antiporter
WP9W18E04_04870	COG0297	glycogen (starch) synthase activity
WP9W18E04_04880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WP9W18E04_04890	COG2813	Specifically methylates the guanine in position
WP9W18E04_04900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP9W18E04_04920	COG1392	Phosphate transport regulator
WP9W18E04_04930	COG0306	phosphate transporter
WP9W18E04_04940	COG0460	homoserine dehydrogenase
WP9W18E04_04940	COG0527	aspartate kinase activity
WP9W18E04_04950	COG0626	cystathionine gamma-synthase activity
WP9W18E04_04970	COG0814	amino acid
WP9W18E04_04980	COG1218	3'(2'),5'-bisphosphate nucleotidase
WP9W18E04_04990	COG0494	nUDIX hydrolase
WP9W18E04_05000	COG1011	Hydrolase
WP9W18E04_05030	COG0110	maltose O-acetyltransferase activity
WP9W18E04_05040	COG3174	membrane
WP9W18E04_05050	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
WP9W18E04_05070	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
WP9W18E04_05080	COG4208	sulfate ABC transporter
WP9W18E04_05090	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
WP9W18E04_05100	COG0583	DNA-binding transcription factor activity
WP9W18E04_05110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP9W18E04_05120	COG0765	amino acid transport
WP9W18E04_05150	COG1126	abc transporter atp-binding protein
WP9W18E04_05160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_05170	COG3397	chitin binding
WP9W18E04_05180	COG0840	transmembrane signaling receptor activity
WP9W18E04_05210	COG1649	PFAM Uncharacterised BCR, COG1649
WP9W18E04_05210	COG0726	polysaccharide deacetylase
WP9W18E04_05220	COG1215	transferase activity, transferring glycosyl groups
WP9W18E04_05250	COG0543	2 iron, 2 sulfur cluster binding
WP9W18E04_05250	COG0633	Ferredoxin
WP9W18E04_05280	COG1328	CTP reductase activity
WP9W18E04_05290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP9W18E04_05320	COG1448	Aminotransferase
WP9W18E04_05400	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_05450	COG3112	Uncharacterised protein family (UPF0231)
WP9W18E04_05470	COG3835	regulator
WP9W18E04_05480	COG2610	gluconate transmembrane transporter activity
WP9W18E04_05490	COG1929	Belongs to the glycerate kinase type-1 family
WP9W18E04_05530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP9W18E04_05550	COG1872	DUF167
WP9W18E04_05560	COG0762	integral membrane protein
WP9W18E04_05570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WP9W18E04_05580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WP9W18E04_05610	COG3022	response to hydroperoxide
WP9W18E04_05650	COG0347	Belongs to the P(II) protein family
WP9W18E04_05660	COG1840	ABC-type Fe3 transport system, periplasmic component
WP9W18E04_05680	COG3842	ATPase activity
WP9W18E04_05690	COG2837	iron assimilation
WP9W18E04_05700	COG1438	arginine binding
WP9W18E04_05710	COG1126	abc transporter atp-binding protein
WP9W18E04_05720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_05730	COG4215	(ABC) transporter
WP9W18E04_05740	COG4160	amino acid transport
WP9W18E04_05750	COG0039	L-malate dehydrogenase activity
WP9W18E04_05760	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WP9W18E04_05770	COG1017	nitric oxide dioxygenase activity
WP9W18E04_05770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP9W18E04_05790	COG4536	flavin adenine dinucleotide binding
WP9W18E04_05800	COG4137	Cytochrome C assembly protein
WP9W18E04_05810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WP9W18E04_05820	COG0228	four-way junction DNA binding
WP9W18E04_05830	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WP9W18E04_05840	COG0336	Belongs to the RNA methyltransferase TrmD family
WP9W18E04_05850	COG0335	large ribosomal subunit rRNA binding
WP9W18E04_05870	COG3066	DNA modification
WP9W18E04_05880	COG1051	belongs to the nudix hydrolase family
WP9W18E04_05900	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WP9W18E04_05910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WP9W18E04_05920	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP9W18E04_05940	COG0583	DNA-binding transcription factor activity
WP9W18E04_05950	COG0640	Transcriptional regulator
WP9W18E04_05960	COG0268	Binds directly to 16S ribosomal RNA
WP9W18E04_05970	COG0728	peptidoglycan biosynthetic process
WP9W18E04_05980	COG0196	riboflavin kinase activity
WP9W18E04_05990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WP9W18E04_06000	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WP9W18E04_06010	COG1047	Peptidyl-prolyl cis-trans
WP9W18E04_06020	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WP9W18E04_06030	COG4968	Prepilin-type N-terminal cleavage methylation domain
WP9W18E04_06100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WP9W18E04_06100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WP9W18E04_06130	COG1854	S-ribosylhomocysteine lyase activity
WP9W18E04_06150	COG4968	Prepilin-type N-terminal cleavage methylation domain
WP9W18E04_06160	COG0084	hydrolase, TatD family'
WP9W18E04_06170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP9W18E04_06190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WP9W18E04_06200	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WP9W18E04_06210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WP9W18E04_06230	COG5002	protein histidine kinase activity
WP9W18E04_06230	COG3447	MASE1 domain protein
WP9W18E04_06230	COG5001	Diguanylate cyclase
WP9W18E04_06250	COG0560	Phosphoserine phosphatase
WP9W18E04_06280	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
WP9W18E04_06290	COG3385	transposase activity
WP9W18E04_06320	COG0776	regulation of translation
WP9W18E04_06340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP9W18E04_06350	COG1914	H( )-stimulated, divalent metal cation uptake system
WP9W18E04_06360	COG0360	Binds together with S18 to 16S ribosomal RNA
WP9W18E04_06370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WP9W18E04_06380	COG0359	binds to the 23S rRNA
WP9W18E04_06390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP9W18E04_06440	COG1064	alcohol dehydrogenase
WP9W18E04_06450	COG1238	metal cluster binding
WP9W18E04_06460	COG0612	Peptidase, M16
WP9W18E04_06470	COG2918	glutathione biosynthetic process
WP9W18E04_06490	COG1022	Amp-dependent synthetase and ligase
WP9W18E04_06510	COG0456	acetyltransferase
WP9W18E04_06560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WP9W18E04_06600	COG0477	Major facilitator Superfamily
WP9W18E04_06610	COG0583	DNA-binding transcription factor activity
WP9W18E04_06620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP9W18E04_06630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WP9W18E04_06650	COG0673	inositol 2-dehydrogenase activity
WP9W18E04_06670	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WP9W18E04_06680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WP9W18E04_06690	COG3036	rescue of stalled ribosome
WP9W18E04_06710	COG0138	bifunctional purine biosynthesis protein purh
WP9W18E04_06720	COG0151	Belongs to the GarS family
WP9W18E04_06770	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP9W18E04_06830	COG0582	viral genome integration into host DNA
WP9W18E04_06840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WP9W18E04_06850	COG0358	DNA primase activity
WP9W18E04_06860	COG1610	YqeY-like protein
WP9W18E04_06870	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WP9W18E04_06880	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WP9W18E04_06890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP9W18E04_06900	COG1027	Aspartate ammonia-lyase
WP9W18E04_06910	COG3030	protein affecting phage T7 exclusion by the F plasmid
WP9W18E04_06920	COG0534	Mate efflux family protein
WP9W18E04_06930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WP9W18E04_06940	COG0459	protein refolding
WP9W18E04_07000	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WP9W18E04_07010	COG3385	transposase activity
WP9W18E04_07020	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WP9W18E04_07030	COG1178	ABC-type Fe3 transport system permease component
WP9W18E04_07040	COG4143	(ABC) transporter
WP9W18E04_07070	COG0066	3-isopropylmalate dehydratase activity
WP9W18E04_07080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WP9W18E04_07090	COG0473	3-isopropylmalate dehydrogenase activity
WP9W18E04_07100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WP9W18E04_07150	COG0028	Belongs to the TPP enzyme family
WP9W18E04_07160	COG0440	acetolactate synthase activity
WP9W18E04_07250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WP9W18E04_07260	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP9W18E04_07280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_07340	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_07350	COG3104	oligopeptide transport
WP9W18E04_07360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WP9W18E04_07370	COG1555	photosystem II stabilization
WP9W18E04_07380	COG0857	belongs to the CobB CobQ family
WP9W18E04_07380	COG0280	phosphate acetyltransferase
WP9W18E04_07390	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP9W18E04_07410	COG3013	Belongs to the UPF0304 family
WP9W18E04_07420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WP9W18E04_07430	COG2716	regulation of RNA biosynthetic process
WP9W18E04_07440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WP9W18E04_07450	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WP9W18E04_07460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WP9W18E04_07530	COG0784	Response regulator, receiver
WP9W18E04_07530	COG5002	protein histidine kinase activity
WP9W18E04_07530	COG2198	Histidine kinase
WP9W18E04_07540	COG0232	Belongs to the dGTPase family. Type 2 subfamily
WP9W18E04_07610	COG1464	Belongs to the NlpA lipoprotein family
WP9W18E04_07620	COG2011	ABC-type metal ion transport system permease component
WP9W18E04_07630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WP9W18E04_07670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WP9W18E04_07670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WP9W18E04_07680	COG0802	atpase or kinase
WP9W18E04_07710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WP9W18E04_07720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WP9W18E04_07730	COG1923	regulation of RNA biosynthetic process
WP9W18E04_07740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WP9W18E04_07750	COG0330	HflC and HflK could
WP9W18E04_07760	COG0330	HflC and HflK could
WP9W18E04_07770	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WP9W18E04_07780	COG0142	geranyltranstransferase activity
WP9W18E04_07790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WP9W18E04_07800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WP9W18E04_07810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WP9W18E04_07840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WP9W18E04_07860	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WP9W18E04_07870	COG2967	ApaG domain
WP9W18E04_07880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WP9W18E04_07890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WP9W18E04_07900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP9W18E04_07910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WP9W18E04_07920	COG3178	'Phosphotransferase
WP9W18E04_07930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WP9W18E04_07940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP9W18E04_07950	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP9W18E04_07970	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WP9W18E04_08010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WP9W18E04_08020	COG3385	transposase activity
WP9W18E04_08050	COG4628	conserved protein (DUF2132)
WP9W18E04_08060	COG0688	phosphatidylethanolamine metabolic process
WP9W18E04_08080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WP9W18E04_08090	COG1278	Cold shock
WP9W18E04_08110	COG0840	transmembrane signaling receptor activity
WP9W18E04_08120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP9W18E04_08130	COG2252	PERMEase
WP9W18E04_08150	COG0488	(ABC) transporter
WP9W18E04_08190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP9W18E04_08200	COG0741	lytic transglycosylase activity
WP9W18E04_08280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP9W18E04_08290	COG4991	sh3 domain protein
WP9W18E04_08310	COG2816	NAD+ diphosphatase activity
WP9W18E04_08320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WP9W18E04_08330	COG1940	carbohydrate kinase activity
WP9W18E04_08340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP9W18E04_08350	COG0126	phosphoglycerate kinase activity
WP9W18E04_08360	COG0191	fructose-bisphosphate aldolase activity
WP9W18E04_08370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP9W18E04_08450	COG0354	folic acid binding
WP9W18E04_08460	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WP9W18E04_08480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WP9W18E04_08490	COG1595	DNA-templated transcription, initiation
WP9W18E04_08500	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
WP9W18E04_08510	COG3026	antisigma factor binding
WP9W18E04_08530	COG0481	GTPase activity
WP9W18E04_08540	COG0681	Belongs to the peptidase S26 family
WP9W18E04_08550	COG0571	ribonuclease III activity
WP9W18E04_08570	COG1381	Involved in DNA repair and RecF pathway recombination
WP9W18E04_08580	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WP9W18E04_08600	COG2350	Protein conserved in bacteria
WP9W18E04_08610	COG2917	probably involved in intracellular septation
WP9W18E04_08620	COG0076	glutamate decarboxylase activity
WP9W18E04_08630	COG1272	protein, Hemolysin III
WP9W18E04_08640	COG2985	domain, Protein
WP9W18E04_08640	COG0569	domain protein
WP9W18E04_08710	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
WP9W18E04_08720	COG2203	Gaf domain
WP9W18E04_08720	COG4251	negative regulation of phosphorylation
WP9W18E04_08720	COG3706	GGDEF domain
WP9W18E04_08720	COG5001	Diguanylate cyclase
WP9W18E04_08780	COG4974	Belongs to the 'phage' integrase family
WP9W18E04_08820	COG0582	viral genome integration into host DNA
WP9W18E04_08840	COG1858	cytochrome C peroxidase
WP9W18E04_08860	COG2313	pseudouridylate synthase activity
WP9W18E04_08870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP9W18E04_08950	COG1765	OsmC-like protein
WP9W18E04_08980	COG3954	Phosphoribulokinase
WP9W18E04_08990	COG3089	Belongs to the UPF0270 family
WP9W18E04_09000	COG3706	GGDEF domain
WP9W18E04_09010	COG0429	hydrolase of the alpha beta-hydrolase fold
WP9W18E04_09020	COG0784	Response regulator, receiver
WP9W18E04_09020	COG0835	chemotaxis
WP9W18E04_09040	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WP9W18E04_09050	COG1047	Peptidyl-prolyl cis-trans
WP9W18E04_09080	COG0305	Participates in initiation and elongation during chromosome replication
WP9W18E04_09090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP9W18E04_09110	COG3340	Belongs to the peptidase S51 family
WP9W18E04_09120	COG1966	Carbon starvation protein
WP9W18E04_09130	COG3279	Response regulator of the LytR AlgR family
WP9W18E04_09140	COG3275	phosphorelay sensor kinase activity
WP9W18E04_09170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP9W18E04_09190	COG3721	Heme iron utilization protein
WP9W18E04_09200	COG0748	coenzyme F420 binding
WP9W18E04_09250	COG2814	Major facilitator Superfamily
WP9W18E04_09260	COG3385	transposase activity
WP9W18E04_09280	COG3655	Transcriptional regulator
WP9W18E04_09300	COG0784	Response regulator, receiver
WP9W18E04_09300	COG5002	protein histidine kinase activity
WP9W18E04_09300	COG2205	protein histidine kinase activity
WP9W18E04_09320	COG3706	GGDEF domain
WP9W18E04_09340	COG2801	Transposase and inactivated derivatives
WP9W18E04_09370	COG3397	chitin binding
WP9W18E04_09410	COG0784	Response regulator, receiver
WP9W18E04_09410	COG0835	chemotaxis
WP9W18E04_09420	COG2755	lipolytic protein G-D-S-L family
WP9W18E04_09430	COG4181	ATPase activity
WP9W18E04_09440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WP9W18E04_09450	COG1090	epimerase
WP9W18E04_09460	COG2200	EAL domain
WP9W18E04_09470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP9W18E04_09480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WP9W18E04_09490	COG3171	Protein conserved in bacteria
WP9W18E04_09500	COG2066	Belongs to the glutaminase family
WP9W18E04_09510	COG2897	thiosulfate sulfurtransferase activity
WP9W18E04_09540	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP9W18E04_09560	COG2966	Psort location CytoplasmicMembrane, score
WP9W18E04_09590	COG4175	Glycine betaine
WP9W18E04_09600	COG4176	ABC-type proline glycine betaine transport system permease component
WP9W18E04_09610	COG2113	Glycine betaine
WP9W18E04_09620	COG0175	sulfate reduction
WP9W18E04_09630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP9W18E04_09640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP9W18E04_09650	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WP9W18E04_09660	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WP9W18E04_09680	COG5001	Diguanylate cyclase
WP9W18E04_09710	COG0786	glutamate:sodium symporter activity
WP9W18E04_09720	COG0252	asparaginase activity
WP9W18E04_09730	COG3139	Protein of unknown function (DUF1315)
WP9W18E04_09770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WP9W18E04_09790	COG0321	lipoyl(octanoyl) transferase activity
WP9W18E04_09800	COG2921	Belongs to the UPF0250 family
WP9W18E04_09810	COG1686	Belongs to the peptidase S11 family
WP9W18E04_09820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP9W18E04_09830	COG2951	lytic endotransglycosylase activity
WP9W18E04_09840	COG0772	Belongs to the SEDS family
WP9W18E04_09850	COG0772	Belongs to the SEDS family
WP9W18E04_09860	COG0768	penicillin binding
WP9W18E04_09870	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WP9W18E04_09880	COG0799	negative regulation of ribosome biogenesis
WP9W18E04_09890	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WP9W18E04_09920	COG0495	leucyl-tRNA aminoacylation
WP9W18E04_09930	COG2888	peptidyl-tyrosine sulfation
WP9W18E04_09940	COG0312	modulator of DNA gyrase
WP9W18E04_09960	COG0716	FMN binding
WP9W18E04_09970	COG4974	Belongs to the 'phage' integrase family
WP9W18E04_09980	COG1970	mechanosensitive ion channel activity
WP9W18E04_10010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WP9W18E04_10020	COG4535	Mg2 and Co2 transporter CorC
WP9W18E04_10030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WP9W18E04_10040	COG1702	phosphate starvation-inducible protein PhoH
WP9W18E04_10050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP9W18E04_10060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP9W18E04_10080	COG3706	GGDEF domain
WP9W18E04_10090	COG0583	DNA-binding transcription factor activity
WP9W18E04_10140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP9W18E04_10160	COG3647	Membrane
WP9W18E04_10170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WP9W18E04_10190	COG0516	GMP reductase activity
WP9W18E04_10210	COG0642	Histidine kinase
WP9W18E04_10240	COG4221	oxidoreductase activity
WP9W18E04_10260	COG1022	Amp-dependent synthetase and ligase
WP9W18E04_10290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP9W18E04_10300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP9W18E04_10320	COG1309	transcriptional regulator
WP9W18E04_10330	COG3214	Protein conserved in bacteria
WP9W18E04_10350	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WP9W18E04_10360	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WP9W18E04_10370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WP9W18E04_10380	COG1053	succinate dehydrogenase
WP9W18E04_10400	COG0584	glycerophosphoryl diester phosphodiesterase
WP9W18E04_10410	COG1511	domain protein
WP9W18E04_10410	COG3264	Mechanosensitive ion channel
WP9W18E04_10430	COG0739	heme binding
WP9W18E04_10450	COG0583	DNA-binding transcription factor activity
WP9W18E04_10490	COG0583	DNA-binding transcription factor activity
WP9W18E04_10500	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WP9W18E04_10560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WP9W18E04_10570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WP9W18E04_10590	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WP9W18E04_10600	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WP9W18E04_10620	COG0180	Tryptophanyl-tRNA synthetase
WP9W18E04_10640	COG0512	Glutamine amidotransferase of anthranilate synthase
WP9W18E04_10650	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WP9W18E04_10670	COG1012	belongs to the aldehyde dehydrogenase family
WP9W18E04_10680	COG1012	belongs to the aldehyde dehydrogenase family
WP9W18E04_10710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP9W18E04_10740	COG0488	(ABC) transporter
WP9W18E04_10760	COG0366	Alpha amylase catalytic
WP9W18E04_10810	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
WP9W18E04_10830	COG0471	metal ion transport
WP9W18E04_10830	COG0490	domain, Protein
WP9W18E04_10840	COG0012	GTP binding
WP9W18E04_10850	COG0193	aminoacyl-tRNA hydrolase activity
WP9W18E04_10860	COG0737	Belongs to the 5'-nucleotidase family
WP9W18E04_10870	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WP9W18E04_10880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WP9W18E04_10890	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WP9W18E04_10900	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WP9W18E04_10910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WP9W18E04_10920	COG2890	protein-(glutamine-N5) methyltransferase activity
WP9W18E04_10940	COG2912	Transglutaminase-like superfamily
WP9W18E04_10950	COG2877	3-deoxy-8-phosphooctulonate synthase activity
WP9W18E04_10960	COG1301	dicarboxylic acid transport
WP9W18E04_10980	COG1301	dicarboxylic acid transport
WP9W18E04_10990	COG0095	Lipoate-protein ligase
WP9W18E04_11000	COG2233	PERMEase
WP9W18E04_11010	COG3706	GGDEF domain
WP9W18E04_11030	COG0534	Mate efflux family protein
WP9W18E04_11050	COG0281	malic enzyme
WP9W18E04_11110	COG0733	neurotransmitter:sodium symporter activity
WP9W18E04_11120	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP9W18E04_11130	COG3706	GGDEF domain
WP9W18E04_11140	COG1566	PFAM secretion protein HlyD family protein
WP9W18E04_11160	COG1032	radical SAM domain protein
WP9W18E04_11210	COG0673	inositol 2-dehydrogenase activity
WP9W18E04_11220	COG2920	part of a sulfur-relay system
WP9W18E04_11230	COG1289	transmembrane transporter activity
WP9W18E04_11240	COG0670	Belongs to the BI1 family
WP9W18E04_11270	COG1486	melibiose metabolic process
WP9W18E04_11280	COG2169	Transcriptional regulator
WP9W18E04_11280	COG1917	Cupin 2, conserved barrel domain protein
WP9W18E04_11290	COG1447	Phosphotransferase system cellobiose-specific component IIA
WP9W18E04_11300	COG2723	6-phospho-beta-galactosidase activity
WP9W18E04_11310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP9W18E04_11320	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
WP9W18E04_11350	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WP9W18E04_11370	COG3156	type II secretion system protein K
WP9W18E04_11380	COG4795	General secretion pathway protein
WP9W18E04_11390	COG2165	general secretion pathway protein
WP9W18E04_11430	COG2165	general secretion pathway protein
WP9W18E04_11440	COG1459	type II secretion system
WP9W18E04_11450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP9W18E04_11470	COG3031	protein transport across the cell outer membrane
WP9W18E04_11490	COG3409	Peptidoglycan-binding domain 1 protein
WP9W18E04_11490	COG3267	Type II secretory pathway component ExeA
WP9W18E04_11500	COG2770	Histidine kinase
WP9W18E04_11500	COG3437	response regulator, receiver
WP9W18E04_11530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WP9W18E04_11540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
WP9W18E04_11550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_11570	COG2190	(PTS) system
WP9W18E04_11580	COG3706	GGDEF domain
WP9W18E04_11590	COG3264	Mechanosensitive ion channel
WP9W18E04_11590	COG1196	nuclear chromosome segregation
WP9W18E04_11600	COG0469	pyruvate kinase activity
WP9W18E04_11620	COG3384	dioxygenase
WP9W18E04_11630	COG0419	ATPase involved in DNA repair
WP9W18E04_11640	COG0420	3'-5' exonuclease activity
WP9W18E04_11660	COG2974	May be involved in recombination
WP9W18E04_11700	COG0531	amino acid
WP9W18E04_11720	COG0531	amino acid
WP9W18E04_11760	COG1917	Cupin 2, conserved barrel domain protein
WP9W18E04_11760	COG1396	sequence-specific DNA binding
WP9W18E04_11770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP9W18E04_11810	COG0464	growth
WP9W18E04_11870	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_11880	COG3038	cytochrome b561
WP9W18E04_11890	COG1720	tRNA m6t6A37 methyltransferase activity
WP9W18E04_11930	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WP9W18E04_11940	COG4988	ABC transporter
WP9W18E04_11950	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_11970	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP9W18E04_12020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP9W18E04_12030	COG3550	peptidyl-serine autophosphorylation
WP9W18E04_12040	COG1396	sequence-specific DNA binding
WP9W18E04_12050	COG1988	membrane-bound metal-dependent
WP9W18E04_12080	COG0159	tryptophan synthase activity
WP9W18E04_12090	COG0133	tryptophan synthase activity
WP9W18E04_12100	COG0134	indole-3-glycerol-phosphate synthase activity
WP9W18E04_12100	COG0135	phosphoribosylanthranilate isomerase activity
WP9W18E04_12110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP9W18E04_12120	COG0512	Glutamine amidotransferase of anthranilate synthase
WP9W18E04_12120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WP9W18E04_12130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WP9W18E04_12150	COG0009	L-threonylcarbamoyladenylate synthase
WP9W18E04_12170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WP9W18E04_12190	COG1946	Acyl-CoA thioesterase
WP9W18E04_12200	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WP9W18E04_12210	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WP9W18E04_12230	COG0083	homoserine kinase activity
WP9W18E04_12240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WP9W18E04_12250	COG3039	Transposase
WP9W18E04_12260	COG1943	Transposase
WP9W18E04_12280	COG0675	Transposase, IS605 OrfB family
WP9W18E04_12300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WP9W18E04_12340	COG1342	Belongs to the UPF0251 family
WP9W18E04_12370	COG1309	transcriptional regulator
WP9W18E04_12380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_12390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP9W18E04_12440	COG1091	dTDP-4-dehydrorhamnose reductase activity
WP9W18E04_12470	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WP9W18E04_12500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP9W18E04_12540	COG0438	transferase activity, transferring glycosyl groups
WP9W18E04_12570	COG3754	Rhamnan synthesis protein F
WP9W18E04_12580	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
WP9W18E04_12590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP9W18E04_12600	COG1051	belongs to the nudix hydrolase family
WP9W18E04_12610	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
WP9W18E04_12610	COG0662	Cupin 2, conserved barrel domain protein
WP9W18E04_12690	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP9W18E04_12710	COG4584	PFAM Integrase catalytic
WP9W18E04_12730	COG1484	DNA-dependent DNA replication
WP9W18E04_12740	COG4584	PFAM Integrase catalytic
WP9W18E04_12750	COG4584	PFAM Integrase catalytic
WP9W18E04_12760	COG1484	DNA-dependent DNA replication
WP9W18E04_12790	COG0577	efflux transmembrane transporter activity
WP9W18E04_12790	COG1136	(ABC) transporter
WP9W18E04_12800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_12820	COG3328	transposase activity
WP9W18E04_12840	COG0675	Transposase, IS605 OrfB family
WP9W18E04_12850	COG1227	inorganic diphosphatase activity
WP9W18E04_12860	COG0497	DNA recombination
WP9W18E04_12870	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WP9W18E04_12880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WP9W18E04_12890	COG0443	Heat shock 70 kDa protein
WP9W18E04_12900	COG0484	heat shock protein binding
WP9W18E04_12960	COG1285	pathogenesis
WP9W18E04_13040	COG1566	PFAM secretion protein HlyD family protein
WP9W18E04_13050	COG0577	efflux transmembrane transporter activity
WP9W18E04_13050	COG1136	(ABC) transporter
WP9W18E04_13060	COG1136	(ABC) transporter
WP9W18E04_13060	COG0577	efflux transmembrane transporter activity
WP9W18E04_13070	COG0577	efflux transmembrane transporter activity
WP9W18E04_13070	COG1136	(ABC) transporter
WP9W18E04_13100	COG0095	Lipoate-protein ligase
WP9W18E04_13120	COG0702	epimerase
WP9W18E04_13130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP9W18E04_13140	COG1454	alcohol dehydrogenase
WP9W18E04_13160	COG0564	pseudouridine synthase activity
WP9W18E04_13220	COG1280	lysine exporter protein (LysE YggA)
WP9W18E04_13250	COG3263	regulation of cellular component size
WP9W18E04_13270	COG1876	peptidase activity
WP9W18E04_13280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP9W18E04_13290	COG1393	Belongs to the ArsC family
WP9W18E04_13310	COG3069	C4-dicarboxylate transmembrane transporter activity
WP9W18E04_13320	COG1473	amidohydrolase
WP9W18E04_13340	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WP9W18E04_13360	COG0017	Asparaginyl-tRNA synthetase
WP9W18E04_13390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WP9W18E04_13400	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WP9W18E04_13410	COG0156	8-amino-7-oxononanoate synthase activity
WP9W18E04_13420	COG2267	carboxylic ester hydrolase activity
WP9W18E04_13420	COG2226	methyltransferase
WP9W18E04_13430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WP9W18E04_13440	COG0501	Belongs to the peptidase M48B family
WP9W18E04_13460	COG0633	Ferredoxin
WP9W18E04_13460	COG3217	Mosc domain protein beta barrel domain protein
WP9W18E04_13460	COG0633	Ferredoxin
WP9W18E04_13460	COG3217	Mosc domain protein beta barrel domain protein
WP9W18E04_13490	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WP9W18E04_13490	COG0674	pyruvate-flavodoxin oxidoreductase activity
WP9W18E04_13490	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WP9W18E04_13490	COG1013	pyruvate-flavodoxin oxidoreductase activity
WP9W18E04_13510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP9W18E04_13520	COG1607	acyl-coa hydrolase
WP9W18E04_13540	COG3021	interspecies interaction between organisms
WP9W18E04_13550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WP9W18E04_13560	COG2027	D-alanyl-D-alanine carboxypeptidase
WP9W18E04_13580	COG2801	Transposase and inactivated derivatives
WP9W18E04_13590	COG1061	Type III restriction enzyme res subunit
WP9W18E04_13600	COG1566	PFAM secretion protein HlyD family protein
WP9W18E04_13620	COG1966	Carbon starvation protein
WP9W18E04_13630	COG3279	Response regulator of the LytR AlgR family
WP9W18E04_13640	COG3275	phosphorelay sensor kinase activity
WP9W18E04_13650	COG2199	diguanylate cyclase activity
WP9W18E04_13650	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP9W18E04_13660	COG2194	sulfuric ester hydrolase activity
WP9W18E04_13670	COG1940	carbohydrate kinase activity
WP9W18E04_13670	COG1846	Transcriptional regulator
WP9W18E04_13680	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP9W18E04_13690	COG0363	glucosamine-6-phosphate deaminase activity
WP9W18E04_13700	COG1263	PTS System
WP9W18E04_13700	COG2190	(PTS) system
WP9W18E04_13700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP9W18E04_13720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP9W18E04_13730	COG0735	belongs to the Fur family
WP9W18E04_13750	COG0716	FMN binding
WP9W18E04_13780	COG0596	Alpha beta hydrolase
WP9W18E04_13790	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WP9W18E04_13800	COG0033	Phosphoglucomutase
WP9W18E04_13810	COG2951	lytic endotransglycosylase activity
WP9W18E04_13820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WP9W18E04_13830	COG4136	ATPase activity
WP9W18E04_13850	COG4134	Bacterial extracellular solute-binding protein
WP9W18E04_13870	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WP9W18E04_13890	COG0675	Transposase, IS605 OrfB family
WP9W18E04_13910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP9W18E04_13930	COG0729	surface antigen
WP9W18E04_13940	COG2911	Protein conserved in bacteria
WP9W18E04_13960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WP9W18E04_13980	COG0741	lytic transglycosylase activity
WP9W18E04_14000	COG4771	TonB-dependent receptor
WP9W18E04_14050	COG1278	Cold shock
WP9W18E04_14100	COG0697	spore germination
WP9W18E04_14110	COG1349	DNA-binding transcription factor activity
WP9W18E04_14120	COG1882	Formate acetyltransferase
WP9W18E04_14130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP9W18E04_14140	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP9W18E04_14170	COG1187	pseudouridine synthase activity
WP9W18E04_14190	COG4166	transmembrane transport
WP9W18E04_14200	COG0622	Phosphoesterase
WP9W18E04_14230	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
WP9W18E04_14240	COG0784	Response regulator, receiver
WP9W18E04_14240	COG0835	chemotaxis
WP9W18E04_14250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
WP9W18E04_14260	COG1815	bacterial-type flagellum-dependent cell motility
WP9W18E04_14280	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
WP9W18E04_14300	COG4787	bacterial-type flagellum-dependent cell motility
WP9W18E04_14320	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WP9W18E04_14330	COG1706	bacterial-type flagellum-dependent cell motility
WP9W18E04_14360	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WP9W18E04_14370	COG2239	Acts as a magnesium transporter
WP9W18E04_14390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WP9W18E04_14400	COG2716	regulation of RNA biosynthetic process
WP9W18E04_14430	COG3852	Histidine kinase
WP9W18E04_14450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WP9W18E04_14460	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WP9W18E04_14470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WP9W18E04_14480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WP9W18E04_14520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WP9W18E04_14540	COG0590	tRNA wobble adenosine to inosine editing
WP9W18E04_14550	COG0573	inorganic phosphate transmembrane transporter activity
WP9W18E04_14560	COG0581	inorganic phosphate transmembrane transporter activity
WP9W18E04_14580	COG0704	Plays a role in the regulation of phosphate uptake
WP9W18E04_14590	COG1253	flavin adenine dinucleotide binding
WP9W18E04_14610	COG1410	methionine synthase
WP9W18E04_14610	COG0646	methionine synthase
WP9W18E04_14620	COG0531	amino acid
WP9W18E04_14650	COG1126	abc transporter atp-binding protein
WP9W18E04_14670	COG0765	amino acid transport
WP9W18E04_14680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_14690	COG3706	GGDEF domain
WP9W18E04_14700	COG2271	Major facilitator Superfamily
WP9W18E04_14720	COG2197	response regulator
WP9W18E04_14730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP9W18E04_14770	COG1785	Belongs to the alkaline phosphatase family
WP9W18E04_14780	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WP9W18E04_14790	COG0123	including yeast histone deacetylase and acetoin utilization protein
WP9W18E04_14800	COG3385	transposase activity
WP9W18E04_14820	COG1199	ATP-dependent helicase activity
WP9W18E04_14840	COG2801	Transposase and inactivated derivatives
WP9W18E04_14860	COG0287	Prephenate dehydrogenase
WP9W18E04_14860	COG1605	Chorismate mutase
WP9W18E04_14870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP9W18E04_14890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP9W18E04_14900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP9W18E04_14970	COG0537	adenosine 5'-monophosphoramidase activity
WP9W18E04_15000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WP9W18E04_15020	COG1301	dicarboxylic acid transport
WP9W18E04_15040	COG2354	Protein conserved in bacteria
WP9W18E04_15060	COG2233	PERMEase
WP9W18E04_15070	COG3150	esterase
WP9W18E04_15080	COG1252	NADH dehydrogenase
WP9W18E04_15100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WP9W18E04_15110	COG3300	MHYT domain
WP9W18E04_15110	COG5001	Diguanylate cyclase
WP9W18E04_15120	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP9W18E04_15140	COG2373	Large extracellular alpha-helical protein
WP9W18E04_15150	COG4953	penicillin-binding protein 1C
WP9W18E04_15180	COG0301	tRNA thio-modification
WP9W18E04_15180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP9W18E04_15190	COG3385	transposase activity
WP9W18E04_15310	COG2801	Transposase and inactivated derivatives
WP9W18E04_15340	COG1083	cytidylyl-transferase
WP9W18E04_15370	COG2801	Transposase and inactivated derivatives
WP9W18E04_15380	COG2801	Transposase and inactivated derivatives
WP9W18E04_15410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP9W18E04_15430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP9W18E04_15460	COG1106	Psort location Cytoplasmic, score
WP9W18E04_15540	COG3385	transposase activity
WP9W18E04_15550	COG2119	membrane
WP9W18E04_15560	COG0023	Translation Initiation Factor
WP9W18E04_15610	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_15630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_15640	COG0765	amino acid transport
WP9W18E04_15650	COG1126	abc transporter atp-binding protein
WP9W18E04_15660	COG0493	'glutamate synthase
WP9W18E04_15670	COG0067	glutamate synthase
WP9W18E04_15670	COG0069	glutamate synthase activity
WP9W18E04_15670	COG0070	glutamate synthase
WP9W18E04_15680	COG1242	4 iron, 4 sulfur cluster binding
WP9W18E04_15810	COG3634	alkyl hydroperoxide reductase activity
WP9W18E04_15830	COG0517	IMP dehydrogenase activity
WP9W18E04_15840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WP9W18E04_15850	COG0343	queuine tRNA-ribosyltransferase activity
WP9W18E04_15860	COG1862	Preprotein translocase
WP9W18E04_15870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP9W18E04_15880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WP9W18E04_15890	COG2897	thiosulfate sulfurtransferase activity
WP9W18E04_15910	COG0826	peptidase U32
WP9W18E04_15920	COG0826	peptidase U32
WP9W18E04_15930	COG3154	lipid carrier protein
WP9W18E04_15970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WP9W18E04_15980	COG0574	Belongs to the PEP-utilizing enzyme family
WP9W18E04_15980	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WP9W18E04_15990	COG2207	Transcriptional regulator
WP9W18E04_16030	COG1464	Belongs to the NlpA lipoprotein family
WP9W18E04_16040	COG3083	sulfuric ester hydrolase activity
WP9W18E04_16050	COG3082	Protein of unknown function (DUF1414)
WP9W18E04_16060	COG3081	Nucleoid-associated protein
WP9W18E04_16080	COG1175	transmembrane transport
WP9W18E04_16090	COG3833	ABC-type maltose transport systems, permease component
WP9W18E04_16100	COG3842	ATPase activity
WP9W18E04_16150	COG0425	Belongs to the sulfur carrier protein TusA family
WP9W18E04_16160	COG4783	chaperone-mediated protein folding
WP9W18E04_16170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP9W18E04_16180	COG1393	Belongs to the ArsC family
WP9W18E04_16200	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
WP9W18E04_16210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WP9W18E04_16220	COG2431	L-lysine efflux transmembrane transporter activity
WP9W18E04_16240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_16260	COG4160	amino acid transport
WP9W18E04_16270	COG0564	pseudouridine synthase activity
WP9W18E04_16300	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WP9W18E04_16320	COG0625	glutathione transferase activity
WP9W18E04_16340	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP9W18E04_16350	COG3069	C4-dicarboxylate transmembrane transporter activity
WP9W18E04_16370	COG0367	asparagine synthase
WP9W18E04_16390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WP9W18E04_16390	COG4651	solute:proton antiporter activity
WP9W18E04_16400	COG0647	UMP catabolic process
WP9W18E04_16440	COG0647	UMP catabolic process
WP9W18E04_16470	COG1902	pentaerythritol trinitrate reductase activity
WP9W18E04_16480	COG1253	flavin adenine dinucleotide binding
WP9W18E04_16500	COG0247	lactate metabolic process
WP9W18E04_16500	COG0277	FAD linked oxidase domain protein
WP9W18E04_16520	COG2050	protein possibly involved in aromatic compounds catabolism
WP9W18E04_16530	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_16540	COG2056	Na+-H+ antiporter family
WP9W18E04_16550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP9W18E04_16560	COG0671	phosphoesterase, PA-phosphatase related
WP9W18E04_16570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP9W18E04_16580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP9W18E04_16600	COG0101	tRNA pseudouridine synthase activity
WP9W18E04_16610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WP9W18E04_16620	COG0285	dihydrofolate synthase activity
WP9W18E04_16630	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WP9W18E04_16640	COG0393	Putative heavy-metal-binding
WP9W18E04_16660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP9W18E04_16660	COG1648	precorrin-2 dehydrogenase activity
WP9W18E04_16700	COG4667	esterase of the alpha-beta hydrolase superfamily
WP9W18E04_16710	COG1368	sulfuric ester hydrolase activity
WP9W18E04_16730	COG0527	aspartate kinase activity
WP9W18E04_16740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP9W18E04_16740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WP9W18E04_16750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WP9W18E04_16790	COG0596	Alpha beta hydrolase
WP9W18E04_16830	COG1136	(ABC) transporter
WP9W18E04_16860	COG2814	Major facilitator Superfamily
WP9W18E04_16900	COG0672	)-iron permease
WP9W18E04_16960	COG0659	secondary active sulfate transmembrane transporter activity
WP9W18E04_16980	COG2801	Transposase and inactivated derivatives
WP9W18E04_17020	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
WP9W18E04_17020	COG0392	lysyltransferase activity
WP9W18E04_17040	COG2205	protein histidine kinase activity
WP9W18E04_17050	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_17060	COG3550	peptidyl-serine autophosphorylation
WP9W18E04_17150	COG4584	PFAM Integrase catalytic
WP9W18E04_17160	COG1484	DNA-dependent DNA replication
WP9W18E04_17240	COG0675	Transposase, IS605 OrfB family
WP9W18E04_17280	COG3039	Transposase
WP9W18E04_17310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP9W18E04_17330	COG1205	dead DEAH box helicase
WP9W18E04_17330	COG1111	helicase
WP9W18E04_17340	COG0210	DNA helicase
WP9W18E04_17480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WP9W18E04_17490	COG1278	Cold shock
WP9W18E04_17500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WP9W18E04_17510	COG0542	response to heat
WP9W18E04_17520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WP9W18E04_17530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WP9W18E04_17540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WP9W18E04_17550	COG3134	Outer membrane lipoprotein
WP9W18E04_17560	COG3706	GGDEF domain
WP9W18E04_17570	COG0492	ferredoxin-NADP+ reductase activity
WP9W18E04_17580	COG0686	Belongs to the AlaDH PNT family
WP9W18E04_17600	COG0531	amino acid
WP9W18E04_17600	COG1674	ftsk spoiiie
WP9W18E04_17610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WP9W18E04_17620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WP9W18E04_17630	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WP9W18E04_17640	COG1286	toxin biosynthetic process
WP9W18E04_17650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WP9W18E04_17670	COG0563	adenylate kinase activity
WP9W18E04_17680	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WP9W18E04_17700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP9W18E04_17730	COG3300	MHYT domain
WP9W18E04_17730	COG5001	Diguanylate cyclase
WP9W18E04_17830	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WP9W18E04_17840	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WP9W18E04_17850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP9W18E04_17860	COG0840	transmembrane signaling receptor activity
WP9W18E04_17880	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_17890	COG0386	Belongs to the glutathione peroxidase family
WP9W18E04_17910	COG1181	Belongs to the D-alanine--D-alanine ligase family
WP9W18E04_17920	COG1570	exodeoxyribonuclease VII activity
WP9W18E04_17930	COG1278	Cold shock
WP9W18E04_17940	COG0517	IMP dehydrogenase activity
WP9W18E04_17940	COG0516	GMP reductase activity
WP9W18E04_17950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WP9W18E04_17950	COG0519	Catalyzes the synthesis of GMP from XMP
WP9W18E04_17970	COG4584	PFAM Integrase catalytic
WP9W18E04_17980	COG1484	DNA-dependent DNA replication
WP9W18E04_18020	COG1025	Belongs to the peptidase M16 family
WP9W18E04_18030	COG2062	phosphohistidine phosphatase, SixA
WP9W18E04_18050	COG0697	spore germination
WP9W18E04_18080	COG0058	SHG alpha-glucan phosphorylase activity
WP9W18E04_18090	COG0471	metal ion transport
WP9W18E04_18100	COG3118	belongs to the thioredoxin family
WP9W18E04_18120	COG1132	(ABC) transporter
WP9W18E04_18130	COG1132	(ABC) transporter
WP9W18E04_18150	COG2501	S4 domain
WP9W18E04_18180	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP9W18E04_18260	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WP9W18E04_18270	COG1053	succinate dehydrogenase
WP9W18E04_18290	COG0567	Dehydrogenase, E1 component
WP9W18E04_18300	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP9W18E04_18310	COG0045	succinate-CoA ligase (ADP-forming) activity
WP9W18E04_18380	COG3088	subunit of a heme lyase
WP9W18E04_18380	COG4235	cytochrome complex assembly
WP9W18E04_18400	COG1138	Cytochrome C-type biogenesis protein
WP9W18E04_18410	COG3301	Polysulphide reductase, NrfD
WP9W18E04_18420	COG0437	4 iron, 4 sulfur cluster binding
WP9W18E04_18430	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WP9W18E04_18470	COG0247	lactate metabolic process
WP9W18E04_18480	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
WP9W18E04_18490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WP9W18E04_18500	COG3012	SEC-C Motif Domain Protein
WP9W18E04_18510	COG0840	transmembrane signaling receptor activity
WP9W18E04_18520	COG1940	carbohydrate kinase activity
WP9W18E04_18520	COG1846	Transcriptional regulator
WP9W18E04_18540	COG0730	response to heat
WP9W18E04_18550	COG0583	DNA-binding transcription factor activity
WP9W18E04_18580	COG3593	DNA synthesis involved in DNA repair
WP9W18E04_18610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP9W18E04_18620	COG1011	Hydrolase
WP9W18E04_18650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP9W18E04_18660	COG2832	Protein of unknown function (DUF454)
WP9W18E04_18670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WP9W18E04_18690	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WP9W18E04_18720	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
WP9W18E04_18740	COG3158	transport of potassium into the cell
WP9W18E04_18750	COG2801	Transposase and inactivated derivatives
WP9W18E04_18800	COG1660	Displays ATPase and GTPase activities
WP9W18E04_18910	COG2801	Transposase and inactivated derivatives
WP9W18E04_18920	COG1695	Transcriptional regulator
WP9W18E04_18960	COG3173	Aminoglycoside phosphotransferase
WP9W18E04_19050	COG3344	reverse transcriptase
WP9W18E04_19090	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP9W18E04_19180	COG2801	Transposase and inactivated derivatives
WP9W18E04_19200	COG2801	Transposase and inactivated derivatives
WP9W18E04_19220	COG1196	nuclear chromosome segregation
WP9W18E04_19230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP9W18E04_19250	COG3385	transposase activity
WP9W18E04_19300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WP9W18E04_19310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP9W18E04_19320	COG3046	protein related to deoxyribodipyrimidine photolyase
WP9W18E04_19340	COG3033	Beta-eliminating lyase
WP9W18E04_19350	COG0295	cytidine deaminase activity
WP9W18E04_19360	COG1346	cytolysis
WP9W18E04_19370	COG1380	Effector of murein hydrolase LrgA
WP9W18E04_19380	COG3345	alpha-galactosidase
WP9W18E04_19400	COG2925	Exonuclease
WP9W18E04_19590	COG2326	polyphosphate kinase activity
WP9W18E04_19600	COG0641	radical SAM
WP9W18E04_19660	COG2304	oxidoreductase activity
WP9W18E04_19690	COG0714	Associated with various cellular activities
WP9W18E04_19700	COG3119	arylsulfatase activity
WP9W18E04_19710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP9W18E04_19720	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
WP9W18E04_19720	COG0617	tRNA 3'-terminal CCA addition
WP9W18E04_19720	COG0517	IMP dehydrogenase activity
WP9W18E04_19730	COG1643	Atp-dependent helicase
WP9W18E04_19750	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WP9W18E04_19780	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
WP9W18E04_19790	COG2067	long-chain fatty acid transport protein
WP9W18E04_19800	COG2067	long-chain fatty acid transport protein
WP9W18E04_19820	COG1595	DNA-templated transcription, initiation
WP9W18E04_19840	COG2304	oxidoreductase activity
WP9W18E04_19880	COG0714	Associated with various cellular activities
WP9W18E04_19890	COG0183	Belongs to the thiolase family
WP9W18E04_19900	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP9W18E04_19900	COG1024	Enoyl-CoA hydratase
WP9W18E04_19910	COG2719	SpoVR family
WP9W18E04_19920	COG2718	Belongs to the UPF0229 family
WP9W18E04_19930	COG2766	serine protein kinase
WP9W18E04_19940	COG0514	ATP-dependent DNA helicase (RecQ)
WP9W18E04_19950	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
WP9W18E04_19970	COG0814	amino acid
WP9W18E04_19980	COG0494	nUDIX hydrolase
WP9W18E04_20010	COG2824	Alkylphosphonate utilization operon protein PhnA
WP9W18E04_20060	COG3706	GGDEF domain
WP9W18E04_20070	COG2840	Smr protein MutS2
WP9W18E04_20080	COG2890	protein-(glutamine-N5) methyltransferase activity
WP9W18E04_20090	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WP9W18E04_20110	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_20120	COG3788	relative of glutathione S-transferase, MAPEG superfamily
WP9W18E04_20130	COG0814	amino acid
WP9W18E04_20140	COG1609	Transcriptional regulator
WP9W18E04_20150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_20150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_20160	COG1105	Belongs to the carbohydrate kinase PfkB family
WP9W18E04_20170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP9W18E04_20170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP9W18E04_20170	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WP9W18E04_20180	COG3313	Fe-S protein
WP9W18E04_20190	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WP9W18E04_20200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP9W18E04_20210	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP9W18E04_20220	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WP9W18E04_20240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP9W18E04_20260	COG0366	Alpha amylase catalytic
WP9W18E04_20300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WP9W18E04_20310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WP9W18E04_20320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WP9W18E04_20330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WP9W18E04_20340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WP9W18E04_20350	COG0072	phenylalanine-tRNA ligase activity
WP9W18E04_20350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP9W18E04_20360	COG0776	regulation of translation
WP9W18E04_20370	COG2205	protein histidine kinase activity
WP9W18E04_20370	COG0784	Response regulator, receiver
WP9W18E04_20410	COG1609	Transcriptional regulator
WP9W18E04_20420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP9W18E04_20430	COG1879	ABC-type sugar transport system periplasmic component
WP9W18E04_20440	COG1172	Belongs to the binding-protein-dependent transport system permease family
WP9W18E04_20450	COG1129	ABC transporter
WP9W18E04_20460	COG1869	D-ribose catabolic process
WP9W18E04_20470	COG0625	glutathione transferase activity
WP9W18E04_20480	COG5654	RES domain protein
WP9W18E04_20510	COG1177	transmembrane transport
WP9W18E04_20560	COG0037	tRNA processing
WP9W18E04_20570	COG0589	response to stress
WP9W18E04_20580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WP9W18E04_20610	COG2217	Heavy metal translocating P-type atpase
WP9W18E04_20630	COG2010	Cytochrome c
WP9W18E04_20660	COG3278	Belongs to the heme-copper respiratory oxidase family
WP9W18E04_20680	COG1956	GAF domain-containing protein
WP9W18E04_20690	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
WP9W18E04_20710	COG0308	aminopeptidase N
WP9W18E04_20730	COG2902	Dehydrogenase
WP9W18E04_20740	COG0167	dihydroorotate dehydrogenase activity
WP9W18E04_20760	COG0254	rRNA binding
WP9W18E04_20770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
WP9W18E04_20780	COG0116	Belongs to the methyltransferase superfamily
WP9W18E04_20780	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP9W18E04_20820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP9W18E04_20830	COG1067	ATP-dependent peptidase activity
WP9W18E04_20870	COG3141	response to X-ray
WP9W18E04_20880	COG0596	Alpha beta hydrolase
WP9W18E04_20890	COG4221	oxidoreductase activity
WP9W18E04_20900	COG4644	lycopene metabolic process
WP9W18E04_20920	COG0840	transmembrane signaling receptor activity
WP9W18E04_21010	COG2079	MmgE PrpD family protein
WP9W18E04_21020	COG0372	Belongs to the citrate synthase family
WP9W18E04_21030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WP9W18E04_21050	COG2995	paraquat-inducible protein a
WP9W18E04_21060	COG3008	intermembrane lipid transfer
WP9W18E04_21070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP9W18E04_21070	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WP9W18E04_21100	COG0084	hydrolase, TatD family'
WP9W18E04_21110	COG0470	DNA polymerase III
WP9W18E04_21120	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WP9W18E04_21130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WP9W18E04_21140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WP9W18E04_21160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WP9W18E04_21170	COG1028	Short-chain dehydrogenase reductase Sdr
WP9W18E04_21190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WP9W18E04_21200	COG0416	fatty acid biosynthetic process
WP9W18E04_21210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WP9W18E04_21230	COG0424	maF-like protein
WP9W18E04_21240	COG0583	DNA-binding transcription factor activity
WP9W18E04_21280	COG0546	phosphoglycolate phosphatase activity
WP9W18E04_21290	COG0564	pseudouridine synthase activity
WP9W18E04_21300	COG1530	ribonuclease E activity
WP9W18E04_21310	COG0306	phosphate transporter
WP9W18E04_21320	COG0717	Belongs to the dCTP deaminase family
WP9W18E04_21330	COG0572	uridine kinase
WP9W18E04_21340	COG0489	protein tyrosine kinase activity
WP9W18E04_21350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP9W18E04_21350	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WP9W18E04_21370	COG1254	Belongs to the acylphosphatase family
WP9W18E04_21380	COG0840	transmembrane signaling receptor activity
WP9W18E04_21390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WP9W18E04_21420	COG0709	Synthesizes selenophosphate from selenide and ATP
WP9W18E04_21430	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WP9W18E04_21440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP9W18E04_21460	COG0318	PFAM AMP-dependent synthetase and ligase
WP9W18E04_21470	COG2267	carboxylic ester hydrolase activity
WP9W18E04_21490	COG1214	PFAM Peptidase M22, glycoprotease
WP9W18E04_21500	COG1199	ATP-dependent helicase activity
WP9W18E04_21520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WP9W18E04_21530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WP9W18E04_21540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WP9W18E04_21550	COG0131	Imidazoleglycerol-phosphate dehydratase
WP9W18E04_21550	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WP9W18E04_21560	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WP9W18E04_21570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WP9W18E04_21580	COG0107	imidazoleglycerol-phosphate synthase activity
WP9W18E04_21610	COG3706	GGDEF domain
WP9W18E04_21620	COG0318	PFAM AMP-dependent synthetase and ligase
WP9W18E04_21630	COG1288	antiporter activity
WP9W18E04_21650	COG3134	Outer membrane lipoprotein
WP9W18E04_21660	COG2080	2 iron, 2 sulfur cluster binding
WP9W18E04_21670	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WP9W18E04_21680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP9W18E04_21690	COG2252	PERMEase
WP9W18E04_21700	COG0402	S-adenosylhomocysteine deaminase activity
WP9W18E04_21710	COG2233	PERMEase
WP9W18E04_21720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WP9W18E04_21720	COG2080	2 iron, 2 sulfur cluster binding
WP9W18E04_21730	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WP9W18E04_21740	COG0402	S-adenosylhomocysteine deaminase activity
WP9W18E04_21750	COG0493	'glutamate synthase
WP9W18E04_21750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP9W18E04_21760	COG2068	MobA-Related Protein
WP9W18E04_21770	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WP9W18E04_21780	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WP9W18E04_21780	COG3608	succinylglutamate desuccinylase aspartoacylase
WP9W18E04_21800	COG0697	spore germination
WP9W18E04_21810	COG0549	Belongs to the carbamate kinase family
WP9W18E04_21830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WP9W18E04_21840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP9W18E04_21850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WP9W18E04_21900	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP9W18E04_21920	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WP9W18E04_21930	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
WP9W18E04_21940	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WP9W18E04_21960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WP9W18E04_21970	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WP9W18E04_21990	COG0205	6-phosphofructokinase activity
WP9W18E04_22010	COG3123	guanosine phosphorylase activity
WP9W18E04_22020	COG1760	l-serine dehydratase
WP9W18E04_22040	COG1760	l-serine dehydratase
WP9W18E04_22050	COG3100	YcgL domain-containing protein
WP9W18E04_22060	COG0850	regulation of cytokinetic process
WP9W18E04_22070	COG2894	cell division
WP9W18E04_22080	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WP9W18E04_22090	COG3099	Belongs to the UPF0263 family
WP9W18E04_22100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP9W18E04_22180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WP9W18E04_22190	COG0697	spore germination
WP9W18E04_22200	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WP9W18E04_22210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP9W18E04_22240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_22250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP9W18E04_22260	COG0307	riboflavin synthase, alpha
WP9W18E04_22310	COG4681	YaeQ
WP9W18E04_22340	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WP9W18E04_22350	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WP9W18E04_22360	COG0586	Pfam SNARE associated Golgi protein
WP9W18E04_22380	COG0556	nucleotide-excision repair
WP9W18E04_22390	COG0569	domain protein
WP9W18E04_22390	COG2985	domain, Protein
WP9W18E04_22400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WP9W18E04_22410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WP9W18E04_22410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WP9W18E04_22440	COG3069	C4-dicarboxylate transmembrane transporter activity
WP9W18E04_22470	COG1451	nucleotide metabolic process
WP9W18E04_22500	COG0417	DNA replication proofreading
WP9W18E04_22520	COG2199	diguanylate cyclase activity
WP9W18E04_22520	COG2203	Gaf domain
WP9W18E04_22550	COG1560	Kdo2-lipid A biosynthetic process
WP9W18E04_22560	COG1560	Kdo2-lipid A biosynthetic process
WP9W18E04_22580	COG0583	DNA-binding transcription factor activity
WP9W18E04_22600	COG1484	DNA-dependent DNA replication
WP9W18E04_22610	COG4584	PFAM Integrase catalytic
WP9W18E04_22620	COG2801	Transposase and inactivated derivatives
WP9W18E04_22650	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP9W18E04_22660	COG0651	ATP synthesis coupled electron transport
WP9W18E04_22670	COG0650	Formate hydrogenlyase subunit 4
WP9W18E04_22680	COG3261	NADH dehydrogenase
WP9W18E04_22680	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
WP9W18E04_22690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP9W18E04_22700	COG3260	NADH ubiquinone oxidoreductase 20
WP9W18E04_22720	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP9W18E04_22730	COG1921	L-seryl-tRNASec selenium transferase activity
WP9W18E04_22750	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WP9W18E04_22760	COG0298	carbon dioxide binding
WP9W18E04_22780	COG0309	Hydrogenase expression formation protein (HypE)
WP9W18E04_22790	COG0375	protein maturation
WP9W18E04_22810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WP9W18E04_22820	COG3842	ATPase activity
WP9W18E04_22850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP9W18E04_22860	COG0601	transmembrane transport
WP9W18E04_22880	COG1773	rubredoxin
WP9W18E04_22890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WP9W18E04_22900	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WP9W18E04_22910	COG5557	Pfam Polysulphide reductase, NrfD
WP9W18E04_22920	COG0437	4 iron, 4 sulfur cluster binding
WP9W18E04_22930	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WP9W18E04_22960	COG3437	response regulator, receiver
WP9W18E04_22970	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WP9W18E04_22980	COG2203	Gaf domain
WP9W18E04_22980	COG3706	GGDEF domain
WP9W18E04_22980	COG4251	negative regulation of phosphorylation
WP9W18E04_22980	COG5001	Diguanylate cyclase
WP9W18E04_22990	COG2801	Transposase and inactivated derivatives
WP9W18E04_23010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WP9W18E04_23080	COG1393	Belongs to the ArsC family
WP9W18E04_23090	COG0798	PFAM Bile acid sodium symporter
WP9W18E04_23120	COG0640	Transcriptional regulator
WP9W18E04_23170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP9W18E04_23210	COG2003	Belongs to the UPF0758 family
WP9W18E04_23270	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP9W18E04_23310	COG0582	viral genome integration into host DNA
WP9W18E04_23320	COG0730	response to heat
WP9W18E04_23340	COG1028	Short-chain dehydrogenase reductase Sdr
WP9W18E04_23360	COG1024	Enoyl-CoA hydratase
WP9W18E04_23370	COG1024	Enoyl-CoA hydratase
WP9W18E04_23380	COG1960	acyl-CoA dehydrogenase activity
WP9W18E04_23390	COG1960	acyl-CoA dehydrogenase activity
WP9W18E04_23400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WP9W18E04_23410	COG1024	Enoyl-CoA hydratase
WP9W18E04_23480	COG1584	GPR1 FUN34 yaaH family protein
WP9W18E04_23510	COG1115	amino acid carrier protein
WP9W18E04_23520	COG1024	Enoyl-CoA hydratase
WP9W18E04_23550	COG3162	membrane
WP9W18E04_23560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP9W18E04_23950	COG0270	DNA (cytosine-5-)-methyltransferase activity
WP9W18E04_24090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP9W18E04_24170	COG2974	May be involved in recombination
WP9W18E04_24270	COG0582	viral genome integration into host DNA
WP9W18E04_24280	COG0488	(ABC) transporter
WP9W18E04_24290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WP9W18E04_24300	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WP9W18E04_24310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WP9W18E04_24320	COG0740	serine-type endopeptidase activity
WP9W18E04_24330	COG0544	peptidyl-prolyl cis-trans isomerase activity
WP9W18E04_24350	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
WP9W18E04_24360	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP9W18E04_24370	COG1136	(ABC) transporter
WP9W18E04_24380	COG4591	ABC-type transport system involved in lipoprotein release permease component
WP9W18E04_24400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WP9W18E04_24410	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WP9W18E04_24420	COG4166	transmembrane transport
WP9W18E04_24430	COG2983	Belongs to the UPF0260 family
WP9W18E04_24440	COG3039	Transposase
WP9W18E04_24450	COG1882	Formate acetyltransferase
WP9W18E04_24460	COG2116	formate transmembrane transporter activity
WP9W18E04_24470	COG1944	ATP diphosphatase activity
WP9W18E04_24480	COG2723	6-phospho-beta-galactosidase activity
WP9W18E04_24490	COG0583	DNA-binding transcription factor activity
WP9W18E04_24510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WP9W18E04_24520	COG0583	DNA-binding transcription factor activity
WP9W18E04_24530	COG0583	DNA-binding transcription factor activity
WP9W18E04_24540	COG0583	DNA-binding transcription factor activity
WP9W18E04_24550	COG2910	NAD(P)H-binding
WP9W18E04_24580	COG1022	Amp-dependent synthetase and ligase
WP9W18E04_24610	COG0861	Integral membrane protein TerC family
WP9W18E04_24620	COG2885	chlorophyll binding
WP9W18E04_24630	COG2199	diguanylate cyclase activity
WP9W18E04_24660	COG2154	pterin-4-alpha-carbinolamine dehydratase
WP9W18E04_24680	COG1012	belongs to the aldehyde dehydrogenase family
WP9W18E04_24690	COG1177	transmembrane transport
WP9W18E04_24700	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP9W18E04_24710	COG3842	ATPase activity
WP9W18E04_24720	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WP9W18E04_24730	COG0583	DNA-binding transcription factor activity
WP9W18E04_24740	COG3768	UPF0283 membrane protein
WP9W18E04_24750	COG3106	COG3106 Predicted ATPase
WP9W18E04_24780	COG1842	Phage shock protein A
WP9W18E04_24790	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WP9W18E04_24800	COG0747	negative chemotaxis
WP9W18E04_24810	COG4168	peptide transport system, permease
WP9W18E04_24840	COG4172	Belongs to the ABC transporter superfamily
WP9W18E04_24850	COG4172	Belongs to the ABC transporter superfamily
WP9W18E04_24860	COG0326	Molecular chaperone. Has ATPase activity
WP9W18E04_24870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WP9W18E04_24900	COG5433	transposase activity
WP9W18E04_24950	COG4974	Belongs to the 'phage' integrase family
WP9W18E04_24990	COG1435	thymidine kinase activity
WP9W18E04_25000	COG1757	Na H antiporter
WP9W18E04_25010	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP9W18E04_25020	COG2096	Adenosyltransferase
WP9W18E04_25030	COG3530	Putative quorum-sensing-regulated virulence factor
WP9W18E04_25040	COG0602	queuosine metabolic process
WP9W18E04_25050	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WP9W18E04_25080	COG0284	orotidine-5'-phosphate decarboxylase activity
WP9W18E04_25090	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WP9W18E04_25110	COG0776	regulation of translation
WP9W18E04_25120	COG0539	negative regulation of cytoplasmic translation
WP9W18E04_25130	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WP9W18E04_25140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP9W18E04_25170	COG2814	Major facilitator Superfamily
WP9W18E04_25200	COG0778	Nitroreductase
WP9W18E04_25210	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
WP9W18E04_25220	COG5001	Diguanylate cyclase
WP9W18E04_25220	COG3300	MHYT domain
WP9W18E04_25240	COG0583	DNA-binding transcription factor activity
WP9W18E04_25250	COG3437	response regulator, receiver
WP9W18E04_25300	COG4989	oxidoreductase activity
WP9W18E04_25310	COG0724	RNA recognition motif
WP9W18E04_25330	COG1126	abc transporter atp-binding protein
WP9W18E04_25340	COG0765	amino acid transport
WP9W18E04_25350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_25360	COG0765	amino acid transport
WP9W18E04_25370	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
WP9W18E04_25390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WP9W18E04_25420	COG4974	Belongs to the 'phage' integrase family
WP9W18E04_25480	COG1484	DNA-dependent DNA replication
WP9W18E04_25490	COG4584	PFAM Integrase catalytic
WP9W18E04_25500	COG2199	diguanylate cyclase activity
WP9W18E04_25500	COG2203	Gaf domain
WP9W18E04_25520	COG2199	diguanylate cyclase activity
WP9W18E04_25520	COG2203	Gaf domain
WP9W18E04_25550	COG3706	GGDEF domain
WP9W18E04_25580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP9W18E04_25610	COG0714	Associated with various cellular activities
WP9W18E04_25620	COG3012	SEC-C Motif Domain Protein
WP9W18E04_25620	COG3318	Belongs to the UPF0149 family
WP9W18E04_25660	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP9W18E04_25670	COG1360	Flagellar Motor Protein
WP9W18E04_25680	COG4771	TonB-dependent receptor
WP9W18E04_25690	COG1770	oligopeptidase
WP9W18E04_25730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP9W18E04_25740	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP9W18E04_25750	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP9W18E04_25750	COG0649	NAD binding
WP9W18E04_25780	COG1034	ATP synthesis coupled electron transport
WP9W18E04_25790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WP9W18E04_25800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP9W18E04_25810	COG0839	Belongs to the complex I subunit 6 family
WP9W18E04_25820	COG0713	ATP synthesis coupled electron transport
WP9W18E04_25840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WP9W18E04_25850	COG1007	ATP synthesis coupled electron transport
WP9W18E04_25860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
WP9W18E04_25860	COG0047	phosphoribosylformylglycinamidine synthase activity
WP9W18E04_25870	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WP9W18E04_25890	COG3385	transposase activity
WP9W18E04_25900	COG1645	bacterial-type flagellum-dependent swarming motility
WP9W18E04_25910	COG1160	GTP binding
WP9W18E04_25920	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WP9W18E04_25930	COG2976	Protein conserved in bacteria
WP9W18E04_25940	COG0124	histidyl-tRNA synthetase
WP9W18E04_25980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WP9W18E04_25990	COG0105	UTP biosynthetic process
WP9W18E04_26020	COG0633	Ferredoxin
WP9W18E04_26030	COG0443	Heat shock 70 kDa protein
WP9W18E04_26040	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WP9W18E04_26060	COG0822	iron-sulfur transferase activity
WP9W18E04_26070	COG1104	cysteine desulfurase activity
WP9W18E04_26080	COG1959	2 iron, 2 sulfur cluster binding
WP9W18E04_26100	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP9W18E04_26100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WP9W18E04_26110	COG0509	glycine decarboxylation via glycine cleavage system
WP9W18E04_26120	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WP9W18E04_26130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP9W18E04_26140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WP9W18E04_26170	COG2814	Major facilitator Superfamily
WP9W18E04_26180	COG0625	glutathione transferase activity
WP9W18E04_26200	COG0483	inositol monophosphate 1-phosphatase activity
WP9W18E04_26230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WP9W18E04_26270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WP9W18E04_26280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
WP9W18E04_26290	COG2089	acid synthase
WP9W18E04_26330	COG2801	Transposase and inactivated derivatives
WP9W18E04_26340	COG4695	Portal protein
WP9W18E04_27110	COG0270	DNA (cytosine-5-)-methyltransferase activity
WP9W18E04_27260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP9W18E04_27320	COG2974	May be involved in recombination
WP9W18E04_27440	COG0322	excinuclease ABC activity
WP9W18E04_27450	COG2197	response regulator
WP9W18E04_27460	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WP9W18E04_27470	COG2835	tetraacyldisaccharide 4'-kinase activity
WP9W18E04_27480	COG1663	tetraacyldisaccharide 4'-kinase activity
WP9W18E04_27500	COG2333	competence protein COMEC
WP9W18E04_27500	COG0658	competence protein
WP9W18E04_27530	COG1448	Aminotransferase
WP9W18E04_27550	COG0583	DNA-binding transcription factor activity
WP9W18E04_27560	COG3085	chromosome segregation
WP9W18E04_27570	COG4574	serine-type endopeptidase inhibitor activity
WP9W18E04_27580	COG0584	glycerophosphoryl diester phosphodiesterase
WP9W18E04_27600	COG1349	DNA-binding transcription factor activity
WP9W18E04_27610	COG2271	Major facilitator Superfamily
WP9W18E04_27620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP9W18E04_27630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WP9W18E04_27640	COG0583	DNA-binding transcription factor activity
WP9W18E04_27690	COG0656	L-ascorbic acid biosynthetic process
WP9W18E04_27710	COG2814	Major facilitator Superfamily
WP9W18E04_27740	COG3220	belongs to the UPF0276 family
WP9W18E04_27780	COG1294	oxidase, subunit
WP9W18E04_27800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP9W18E04_27810	COG2979	Protein of unknown function (DUF533)
WP9W18E04_27840	COG0583	DNA-binding transcription factor activity
WP9W18E04_27860	COG2807	transmembrane transport
WP9W18E04_27870	COG1187	pseudouridine synthase activity
WP9W18E04_27890	COG0346	lactoylglutathione lyase activity
WP9W18E04_27910	COG1061	Type III restriction enzyme res subunit
WP9W18E04_27920	COG4657	Part of a membrane complex involved in electron transport
WP9W18E04_27930	COG2878	Part of a membrane complex involved in electron transport
WP9W18E04_27950	COG4658	electron transport chain
WP9W18E04_27960	COG4659	FMN binding
WP9W18E04_27970	COG4660	Part of a membrane complex involved in electron transport
WP9W18E04_27980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WP9W18E04_27990	COG0346	lactoylglutathione lyase activity
WP9W18E04_28060	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WP9W18E04_28070	COG0505	Belongs to the CarA family
WP9W18E04_28080	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WP9W18E04_28100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WP9W18E04_28110	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WP9W18E04_28120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WP9W18E04_28130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WP9W18E04_28140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WP9W18E04_28150	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
WP9W18E04_28220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WP9W18E04_28230	COG3385	transposase activity
WP9W18E04_28240	COG0861	Integral membrane protein TerC family
WP9W18E04_28270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP9W18E04_28280	COG0601	transmembrane transport
WP9W18E04_28300	COG2095	MarC family integral membrane protein
WP9W18E04_28310	COG1454	alcohol dehydrogenase
WP9W18E04_28310	COG1012	belongs to the aldehyde dehydrogenase family
WP9W18E04_28320	COG0217	transcriptional regulatory protein
WP9W18E04_28330	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WP9W18E04_28350	COG1801	Protein of unknown function DUF72
WP9W18E04_28360	COG4106	trans-aconitate 2-methyltransferase activity
WP9W18E04_28370	COG0500	methyltransferase
WP9W18E04_28410	COG0450	alkyl hydroperoxide reductase
WP9W18E04_28420	COG0583	DNA-binding transcription factor activity
WP9W18E04_28430	COG0791	NLP P60 protein
WP9W18E04_28450	COG0583	DNA-binding transcription factor activity
WP9W18E04_28460	COG2610	gluconate transmembrane transporter activity
WP9W18E04_28470	COG3048	D-serine ammonia-lyase activity
WP9W18E04_28490	COG0538	isocitrate dehydrogenase activity
WP9W18E04_28500	COG2207	Transcriptional regulator
WP9W18E04_28520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP9W18E04_28530	COG0659	secondary active sulfate transmembrane transporter activity
WP9W18E04_28540	COG0589	response to stress
WP9W18E04_28570	COG3152	Membrane
WP9W18E04_28640	COG1309	transcriptional regulator
WP9W18E04_28660	COG1454	alcohol dehydrogenase
WP9W18E04_28700	COG0534	Mate efflux family protein
WP9W18E04_28720	COG2841	Protein conserved in bacteria
WP9W18E04_28740	COG3300	MHYT domain
WP9W18E04_28740	COG5001	Diguanylate cyclase
WP9W18E04_28750	COG3132	Protein of unknown function, DUF480
WP9W18E04_28820	COG0708	Exodeoxyribonuclease III
WP9W18E04_28870	COG1122	ATPase activity
WP9W18E04_28880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_28940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_28950	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP9W18E04_28980	COG1120	ATPase activity
WP9W18E04_28990	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP9W18E04_29000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WP9W18E04_29020	COG4771	TonB-dependent receptor
WP9W18E04_29030	COG2375	cellular response to nickel ion
WP9W18E04_29040	COG0784	Response regulator, receiver
WP9W18E04_29040	COG3437	response regulator, receiver
WP9W18E04_29060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WP9W18E04_29070	COG0328	RNA-DNA hybrid ribonuclease activity
WP9W18E04_29080	COG2226	methyltransferase
WP9W18E04_29090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WP9W18E04_29100	COG0741	lytic transglycosylase activity
WP9W18E04_29100	COG1388	LysM domain
WP9W18E04_29150	COG1376	ErfK ybiS ycfS ynhG family protein
WP9W18E04_29150	COG1388	LysM domain
WP9W18E04_29170	COG0471	metal ion transport
WP9W18E04_29190	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
WP9W18E04_29200	COG0791	NLP P60 protein
WP9W18E04_29240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WP9W18E04_29250	COG0788	formyltetrahydrofolate deformylase activity
WP9W18E04_29270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP9W18E04_29300	COG0739	heme binding
WP9W18E04_29300	COG0741	lytic transglycosylase activity
WP9W18E04_29300	COG1196	nuclear chromosome segregation
WP9W18E04_29310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WP9W18E04_29330	COG0436	Aminotransferase
WP9W18E04_29340	COG1288	antiporter activity
WP9W18E04_29350	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WP9W18E04_29360	COG1879	ABC-type sugar transport system periplasmic component
WP9W18E04_29390	COG2964	Protein conserved in bacteria
WP9W18E04_29400	COG3681	Belongs to the UPF0597 family
WP9W18E04_29410	COG0251	oxidation-reduction process
WP9W18E04_29420	COG0814	amino acid
WP9W18E04_29460	COG2015	COG2015, Alkyl sulfatase and related hydrolases
WP9W18E04_29480	COG1166	arginine decarboxylase activity
WP9W18E04_29490	COG2195	Cleaves the N-terminal amino acid of tripeptides
WP9W18E04_29520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WP9W18E04_29540	COG2353	YceI-like domain
WP9W18E04_29550	COG0583	DNA-binding transcription factor activity
WP9W18E04_29570	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WP9W18E04_29580	COG0840	transmembrane signaling receptor activity
WP9W18E04_29590	COG0302	gtp cyclohydrolase
WP9W18E04_29600	COG0303	'Molybdopterin
WP9W18E04_29610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WP9W18E04_29620	COG3385	transposase activity
WP9W18E04_29630	COG2267	carboxylic ester hydrolase activity
WP9W18E04_29640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WP9W18E04_29680	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WP9W18E04_29690	COG0315	cyclic pyranopterin monophosphate synthase activity
WP9W18E04_29700	COG0521	Mo-molybdopterin cofactor biosynthetic process
WP9W18E04_29710	COG3005	denitrification pathway
WP9W18E04_29730	COG0348	domain, Protein
WP9W18E04_29740	COG0437	4 iron, 4 sulfur cluster binding
WP9W18E04_29750	COG0243	molybdopterin cofactor binding
WP9W18E04_29770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP9W18E04_29780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WP9W18E04_29790	COG3850	Histidine kinase
WP9W18E04_29800	COG2197	response regulator
WP9W18E04_29860	COG0121	glutamine amidotransferase
WP9W18E04_29870	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP9W18E04_29880	COG1960	acyl-CoA dehydrogenase activity
WP9W18E04_29890	COG1473	amidohydrolase
WP9W18E04_29900	COG2914	Belongs to the UPF0125 (RnfH) family
WP9W18E04_29910	COG2867	negative regulation of translational initiation
WP9W18E04_29920	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WP9W18E04_29930	COG0784	Response regulator, receiver
WP9W18E04_29930	COG2205	protein histidine kinase activity
WP9W18E04_29950	COG3383	formate dehydrogenase (NAD+) activity
WP9W18E04_30100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WP9W18E04_30120	COG1960	acyl-CoA dehydrogenase activity
WP9W18E04_30130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WP9W18E04_30150	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WP9W18E04_30160	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP9W18E04_30170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP9W18E04_30170	COG1263	PTS System
WP9W18E04_30180	COG1609	Transcriptional regulator
WP9W18E04_30260	COG0737	Belongs to the 5'-nucleotidase family
WP9W18E04_30270	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP9W18E04_30270	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP9W18E04_30270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_30310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WP9W18E04_30330	COG1187	pseudouridine synthase activity
WP9W18E04_30340	COG1051	belongs to the nudix hydrolase family
WP9W18E04_30350	COG0482	sulfurtransferase activity
WP9W18E04_30360	COG2915	High frequency lysogenization protein hflD homolog
WP9W18E04_30370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WP9W18E04_30380	COG2850	peptidyl-arginine hydroxylation
WP9W18E04_30420	COG0625	glutathione transferase activity
WP9W18E04_30430	COG0259	pyridoxamine-phosphate oxidase activity
WP9W18E04_30440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP9W18E04_30440	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WP9W18E04_30450	COG0251	oxidation-reduction process
WP9W18E04_30460	COG1882	Formate acetyltransferase
WP9W18E04_30470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WP9W18E04_30490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP9W18E04_30500	COG1484	DNA-dependent DNA replication
WP9W18E04_30510	COG4584	PFAM Integrase catalytic
WP9W18E04_30520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WP9W18E04_30530	COG3385	transposase activity
WP9W18E04_30540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WP9W18E04_30560	COG2853	Lipoprotein
WP9W18E04_30580	COG4235	cytochrome complex assembly
WP9W18E04_30580	COG3088	subunit of a heme lyase
WP9W18E04_30590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP9W18E04_30600	COG1138	Cytochrome C-type biogenesis protein
WP9W18E04_30610	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WP9W18E04_30620	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP9W18E04_30630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP9W18E04_30640	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WP9W18E04_30670	COG0835	chemotaxis
WP9W18E04_30690	COG1192	Involved in chromosome partitioning
WP9W18E04_30700	COG1360	Flagellar Motor Protein
WP9W18E04_30710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP9W18E04_30720	COG2201	protein-glutamate methylesterase activity
WP9W18E04_30730	COG0784	Response regulator, receiver
WP9W18E04_30730	COG0643	Histidine kinase
WP9W18E04_30730	COG2198	Histidine kinase
WP9W18E04_30740	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WP9W18E04_30790	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WP9W18E04_30810	COG1684	flagellar biosynthetic protein fliR
WP9W18E04_30920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WP9W18E04_30940	COG1677	Flagellar hook-basal body complex protein FliE
WP9W18E04_30970	COG0469	pyruvate kinase activity
WP9W18E04_30980	COG1737	Transcriptional regulator
WP9W18E04_30990	COG0837	glucose binding
WP9W18E04_31050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WP9W18E04_31070	COG0281	malic enzyme
WP9W18E04_31110	COG0437	4 iron, 4 sulfur cluster binding
WP9W18E04_31120	COG3383	formate dehydrogenase (NAD+) activity
WP9W18E04_31120	COG3383	formate dehydrogenase (NAD+) activity
WP9W18E04_31200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WP9W18E04_31220	COG3852	Histidine kinase
WP9W18E04_31250	COG4662	Binding-protein-dependent transport system inner membrane component
WP9W18E04_31270	COG0746	molybdenum cofactor guanylyltransferase activity
WP9W18E04_31280	COG0303	'Molybdopterin
WP9W18E04_31290	COG1289	transmembrane transporter activity
WP9W18E04_31350	COG0784	Response regulator, receiver
WP9W18E04_31350	COG2205	protein histidine kinase activity
WP9W18E04_31380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WP9W18E04_31390	COG0444	Belongs to the ABC transporter superfamily
WP9W18E04_31400	COG4608	Belongs to the ABC transporter superfamily
WP9W18E04_31420	COG2971	BadF BadG BcrA BcrD
WP9W18E04_31470	COG3724	N-succinylarginine dihydrolase activity
WP9W18E04_31500	COG2197	response regulator
WP9W18E04_31520	COG3188	usher protein
WP9W18E04_31560	COG2203	Gaf domain
WP9W18E04_31560	COG2199	diguanylate cyclase activity
WP9W18E04_31560	COG2200	EAL domain
WP9W18E04_31580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WP9W18E04_31600	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WP9W18E04_31610	COG3706	GGDEF domain
WP9W18E04_31620	COG2211	Major facilitator Superfamily
WP9W18E04_31630	COG0616	signal peptide processing
WP9W18E04_31640	COG1028	Short-chain dehydrogenase reductase Sdr
WP9W18E04_31650	COG0583	DNA-binding transcription factor activity
WP9W18E04_31670	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WP9W18E04_31710	COG3408	Glycogen debranching enzyme
WP9W18E04_31710	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WP9W18E04_31730	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WP9W18E04_31760	COG3385	transposase activity
WP9W18E04_31770	COG3385	transposase activity
WP9W18E04_31780	COG1115	amino acid carrier protein
WP9W18E04_31790	COG0019	diaminopimelate decarboxylase activity
WP9W18E04_31810	COG0678	peroxiredoxin activity
WP9W18E04_31860	COG0545	Peptidyl-prolyl cis-trans isomerase
WP9W18E04_31870	COG3142	Participates in the control of copper homeostasis
WP9W18E04_31920	COG5002	protein histidine kinase activity
WP9W18E04_31930	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_31940	COG0346	lactoylglutathione lyase activity
WP9W18E04_31960	COG0697	spore germination
WP9W18E04_31980	COG3290	protein histidine kinase activity
WP9W18E04_31990	COG0281	malic enzyme
WP9W18E04_32010	COG1846	Transcriptional regulator
WP9W18E04_32080	COG0602	queuosine metabolic process
WP9W18E04_32120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WP9W18E04_32130	COG3115	cell septum assembly
WP9W18E04_32140	COG1196	nuclear chromosome segregation
WP9W18E04_32160	COG2860	membrane
WP9W18E04_32180	COG3108	Peptidase M15
WP9W18E04_32190	COG2989	Protein conserved in bacteria
WP9W18E04_32220	COG0463	Glycosyl transferase, family 2
WP9W18E04_32250	COG0366	Alpha amylase catalytic
WP9W18E04_32320	COG2203	Gaf domain
WP9W18E04_32320	COG2199	diguanylate cyclase activity
WP9W18E04_32340	COG3590	peptidase
WP9W18E04_32360	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WP9W18E04_32370	COG1982	Orn Lys Arg decarboxylase major
WP9W18E04_32380	COG0531	amino acid
WP9W18E04_32390	COG3710	Transcriptional regulator
WP9W18E04_32400	COG0488	(ABC) transporter
WP9W18E04_32420	COG0531	amino acid
WP9W18E04_32450	COG0814	amino acid
WP9W18E04_32480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP9W18E04_32490	COG0739	heme binding
WP9W18E04_32500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WP9W18E04_32520	COG0251	oxidation-reduction process
WP9W18E04_32540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WP9W18E04_32560	COG3091	SprT-like family
WP9W18E04_32580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WP9W18E04_32590	COG0189	ligase activity
WP9W18E04_32610	COG1678	Uncharacterized ACR, COG1678
WP9W18E04_32620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WP9W18E04_32630	COG3104	oligopeptide transport
WP9W18E04_32700	COG0714	Associated with various cellular activities
WP9W18E04_32730	COG1115	amino acid carrier protein
WP9W18E04_32740	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WP9W18E04_32760	COG0825	malonyl-CoA metabolic process
WP9W18E04_32780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WP9W18E04_32790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP9W18E04_32800	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP9W18E04_32810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WP9W18E04_32820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WP9W18E04_32850	COG0750	zinc metalloprotease
WP9W18E04_32860	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WP9W18E04_32870	COG0575	Belongs to the CDS family
WP9W18E04_32880	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WP9W18E04_32890	COG0233	cytoplasmic translational termination
WP9W18E04_32900	COG0528	UMP kinase activity
WP9W18E04_32910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WP9W18E04_32920	COG0052	Belongs to the universal ribosomal protein uS2 family
WP9W18E04_32930	COG0024	Methionine aminopeptidase
WP9W18E04_32940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
WP9W18E04_32950	COG2171	N-acyltransferase activity
WP9W18E04_32970	COG3385	transposase activity
WP9W18E04_32980	COG1263	PTS System
WP9W18E04_32980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP9W18E04_33020	COG0564	pseudouridine synthase activity
WP9W18E04_33030	COG3098	single-species biofilm formation
WP9W18E04_33080	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
WP9W18E04_33100	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP9W18E04_33100	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WP9W18E04_33130	COG3706	GGDEF domain
WP9W18E04_33140	COG1611	Belongs to the LOG family
WP9W18E04_33150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WP9W18E04_33160	COG0473	3-isopropylmalate dehydrogenase activity
WP9W18E04_33180	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
WP9W18E04_33190	COG2363	Small membrane protein
WP9W18E04_33210	COG0583	DNA-binding transcription factor activity
WP9W18E04_33220	COG0840	transmembrane signaling receptor activity
WP9W18E04_33230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WP9W18E04_33260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WP9W18E04_33270	COG1666	GTP binding
WP9W18E04_33280	COG3248	Nucleoside-binding outer membrane protein
WP9W18E04_33290	COG2211	Major facilitator Superfamily
WP9W18E04_33300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WP9W18E04_33320	COG2813	Specifically methylates the guanine in position
WP9W18E04_33330	COG0271	Belongs to the BolA IbaG family
WP9W18E04_33340	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP9W18E04_33350	COG1805	sodium ion transport
WP9W18E04_33360	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP9W18E04_33370	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP9W18E04_33380	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WP9W18E04_33390	COG2871	sodium ion transport
WP9W18E04_33400	COG1477	protein flavinylation
WP9W18E04_33460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WP9W18E04_33490	COG0300	oxidoreductase activity
WP9W18E04_33510	COG0415	Belongs to the DNA photolyase family
WP9W18E04_33520	COG0789	Transcriptional regulator
WP9W18E04_33530	COG3272	Protein of unknown function (DUF1722)
WP9W18E04_33590	COG1605	Chorismate mutase
WP9W18E04_33590	COG0077	Prephenate dehydratase
WP9W18E04_33660	COG0300	oxidoreductase activity
WP9W18E04_33710	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WP9W18E04_33790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
WP9W18E04_33800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP9W18E04_33820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WP9W18E04_33830	COG0826	peptidase U32
WP9W18E04_33840	COG1280	lysine exporter protein (LysE YggA)
WP9W18E04_33880	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_33900	COG2198	Histidine kinase
WP9W18E04_33900	COG0643	Histidine kinase
WP9W18E04_33920	COG0835	chemotaxis
WP9W18E04_33930	COG0840	transmembrane signaling receptor activity
WP9W18E04_33950	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
WP9W18E04_33960	COG2201	protein-glutamate methylesterase activity
WP9W18E04_33970	COG1185	polyribonucleotide nucleotidyltransferase activity
WP9W18E04_33980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WP9W18E04_33990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WP9W18E04_34000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WP9W18E04_34010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WP9W18E04_34020	COG0195	Participates in both transcription termination and antitermination
WP9W18E04_34030	COG0779	Required for maturation of 30S ribosomal subunits
WP9W18E04_34040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WP9W18E04_34050	COG0149	triose-phosphate isomerase activity
WP9W18E04_34060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WP9W18E04_34070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WP9W18E04_34090	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WP9W18E04_34100	COG1534	Rna-binding protein
WP9W18E04_34130	COG1360	Flagellar Motor Protein
WP9W18E04_34140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WP9W18E04_34150	COG1722	exodeoxyribonuclease VII activity
WP9W18E04_34160	COG0142	geranyltranstransferase activity
WP9W18E04_34170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WP9W18E04_34180	COG3385	transposase activity
WP9W18E04_34190	COG0737	Belongs to the 5'-nucleotidase family
WP9W18E04_34230	COG2204	response regulator
WP9W18E04_34240	COG0545	Peptidyl-prolyl cis-trans isomerase
WP9W18E04_34260	COG2900	Belongs to the SlyX family
WP9W18E04_34310	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WP9W18E04_34320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WP9W18E04_34330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WP9W18E04_34340	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WP9W18E04_34370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP9W18E04_34370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WP9W18E04_34380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WP9W18E04_34390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WP9W18E04_34410	COG2198	Histidine kinase
WP9W18E04_34410	COG0784	Response regulator, receiver
WP9W18E04_34410	COG2205	protein histidine kinase activity
WP9W18E04_34420	COG1879	ABC-type sugar transport system periplasmic component
WP9W18E04_34440	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_34450	COG3005	denitrification pathway
WP9W18E04_34470	COG3381	protein complex oligomerization
WP9W18E04_34530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP9W18E04_34540	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WP9W18E04_34550	COG0511	ligase activity, forming carbon-carbon bonds
WP9W18E04_34560	COG0439	Biotin carboxylase
WP9W18E04_34570	COG3924	membrane
WP9W18E04_34580	COG4145	pantothenate transmembrane transporter activity
WP9W18E04_34590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP9W18E04_34590	COG2190	(PTS) system
WP9W18E04_34590	COG1263	PTS System
WP9W18E04_34600	COG0583	DNA-binding transcription factor activity
WP9W18E04_34610	COG0604	alcohol dehydrogenase
WP9W18E04_34620	COG2264	protein methyltransferase activity
WP9W18E04_34630	COG0110	maltose O-acetyltransferase activity
WP9W18E04_34640	COG0778	Nitroreductase
WP9W18E04_34650	COG0446	pyridine nucleotide-disulphide oxidoreductase
WP9W18E04_34650	COG1902	pentaerythritol trinitrate reductase activity
WP9W18E04_34660	COG0616	signal peptide processing
WP9W18E04_34700	COG0848	biopolymer transport protein
WP9W18E04_34710	COG0811	peptide transport
WP9W18E04_34720	COG0811	peptide transport
WP9W18E04_34750	COG4174	ABC transporter (Permease)
WP9W18E04_34760	COG4239	(ABC) transporter, permease
WP9W18E04_34780	COG0444	Belongs to the ABC transporter superfamily
WP9W18E04_34790	COG4608	Belongs to the ABC transporter superfamily
WP9W18E04_34800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WP9W18E04_34810	COG2801	Transposase and inactivated derivatives
WP9W18E04_34850	COG2188	Transcriptional regulator
WP9W18E04_34890	COG2816	NAD+ diphosphatase activity
WP9W18E04_34940	COG3385	transposase activity
WP9W18E04_34950	COG1858	cytochrome C peroxidase
WP9W18E04_34960	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
WP9W18E04_34980	COG2199	diguanylate cyclase activity
WP9W18E04_34980	COG2203	Gaf domain
WP9W18E04_34990	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_35030	COG0154	amidase activity
WP9W18E04_35040	COG2957	Belongs to the agmatine deiminase family
WP9W18E04_35070	COG1902	pentaerythritol trinitrate reductase activity
WP9W18E04_35100	COG1238	metal cluster binding
WP9W18E04_35110	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WP9W18E04_35120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WP9W18E04_35130	COG0585	pseudouridine synthase activity
WP9W18E04_35150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WP9W18E04_35160	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WP9W18E04_35170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WP9W18E04_35190	COG1376	ErfK ybiS ycfS ynhG family protein
WP9W18E04_35200	COG0668	transmembrane transport
WP9W18E04_35220	COG2731	YhcH YjgK YiaL family protein
WP9W18E04_35240	COG1794	racemase activity, acting on amino acids and derivatives
WP9W18E04_35270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WP9W18E04_35310	COG0488	(ABC) transporter
WP9W18E04_35330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WP9W18E04_35410	COG0148	phosphopyruvate hydratase activity
WP9W18E04_35420	COG0504	CTP synthase activity
WP9W18E04_35430	COG3956	TIGRFAM MazG family protein
WP9W18E04_35440	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WP9W18E04_35450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP9W18E04_35470	COG4807	Protein conserved in bacteria
WP9W18E04_35480	COG3023	N-Acetylmuramoyl-L-alanine amidase
WP9W18E04_35490	COG0783	Belongs to the Dps family
WP9W18E04_35500	COG1151	hydroxylamine reductase activity
WP9W18E04_35510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WP9W18E04_35520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP9W18E04_35530	COG0671	phosphoesterase, PA-phosphatase related
WP9W18E04_35540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP9W18E04_35550	COG0163	prenyltransferase activity
WP9W18E04_35580	COG1131	(ABC) transporter
WP9W18E04_35590	COG0842	Transport permease protein
WP9W18E04_35600	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
WP9W18E04_35610	COG1924	4 iron, 4 sulfur cluster binding
WP9W18E04_35640	COG1129	ABC transporter
WP9W18E04_35660	COG1486	melibiose metabolic process
WP9W18E04_35710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WP9W18E04_35720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WP9W18E04_35730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WP9W18E04_35740	COG0617	tRNA 3'-terminal CCA addition
WP9W18E04_35750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WP9W18E04_35760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WP9W18E04_35770	COG1489	DNA binding
WP9W18E04_35790	COG1643	Atp-dependent helicase
WP9W18E04_35800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WP9W18E04_35810	COG0346	lactoylglutathione lyase activity
WP9W18E04_35820	COG2076	Multidrug Resistance protein
WP9W18E04_35830	COG2076	Multidrug Resistance protein
WP9W18E04_35840	COG0583	DNA-binding transcription factor activity
WP9W18E04_35850	COG0784	Response regulator, receiver
WP9W18E04_35850	COG3437	response regulator, receiver
WP9W18E04_35860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WP9W18E04_35890	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
WP9W18E04_35910	COG1136	(ABC) transporter
WP9W18E04_35960	COG0529	Catalyzes the synthesis of activated sulfate
WP9W18E04_35970	COG0471	metal ion transport
WP9W18E04_35970	COG3273	potassium ion transport
WP9W18E04_35980	COG2895	sulfate adenylyltransferase (ATP) activity
WP9W18E04_35990	COG0175	sulfate reduction
WP9W18E04_36000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP9W18E04_36000	COG1648	precorrin-2 dehydrogenase activity
WP9W18E04_36010	COG0330	HflC and HflK could
WP9W18E04_36020	COG1585	Membrane protein implicated in regulation of membrane protease activity
WP9W18E04_36030	COG0840	transmembrane signaling receptor activity
WP9W18E04_36040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WP9W18E04_36050	COG0676	glucose-6-phosphate 1-epimerase activity
WP9W18E04_36060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WP9W18E04_36070	COG1640	4-alpha-glucanotransferase
WP9W18E04_36080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WP9W18E04_36160	COG0561	phosphatase activity
WP9W18E04_36190	COG0733	neurotransmitter:sodium symporter activity
WP9W18E04_36210	COG0733	neurotransmitter:sodium symporter activity
WP9W18E04_36220	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WP9W18E04_36230	COG2885	chlorophyll binding
WP9W18E04_36240	COG0823	Involved in the tonB-independent uptake of proteins
WP9W18E04_36270	COG0811	peptide transport
WP9W18E04_36280	COG0824	Thioesterase
WP9W18E04_36290	COG3790	cyd operon protein YbgE
WP9W18E04_36300	COG4890	Cyd operon protein YbgT
WP9W18E04_36310	COG1294	oxidase, subunit
WP9W18E04_36330	COG2255	four-way junction helicase activity
WP9W18E04_36340	COG0632	four-way junction helicase activity
WP9W18E04_36350	COG0840	transmembrane signaling receptor activity
WP9W18E04_36380	COG2771	luxR family
WP9W18E04_36390	COG3916	Acyl-homoserine-lactone synthase
WP9W18E04_36410	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
WP9W18E04_36420	COG5001	Diguanylate cyclase
WP9W18E04_36420	COG4251	negative regulation of phosphorylation
WP9W18E04_36420	COG3706	GGDEF domain
WP9W18E04_36420	COG2203	Gaf domain
WP9W18E04_36440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WP9W18E04_36460	COG2995	paraquat-inducible protein a
WP9W18E04_36470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP9W18E04_36470	COG3008	intermembrane lipid transfer
WP9W18E04_36490	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP9W18E04_36500	COG0442	prolyl-tRNA aminoacylation
WP9W18E04_36510	COG4221	oxidoreductase activity
WP9W18E04_36540	COG1024	Enoyl-CoA hydratase
WP9W18E04_36570	COG4166	transmembrane transport
WP9W18E04_36590	COG0840	transmembrane signaling receptor activity
WP9W18E04_36600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WP9W18E04_36610	COG0735	belongs to the Fur family
WP9W18E04_36660	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WP9W18E04_36670	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_36680	COG2153	protein acetylation
WP9W18E04_36700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WP9W18E04_36710	COG0557	exoribonuclease II activity
WP9W18E04_36720	COG3706	GGDEF domain
WP9W18E04_36730	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WP9W18E04_36730	COG2885	chlorophyll binding
WP9W18E04_36740	COG3240	lipase activity
WP9W18E04_36750	COG3385	transposase activity
WP9W18E04_36760	COG3111	PFAM Bacterial OB fold (BOF) protein
WP9W18E04_36780	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WP9W18E04_36790	COG1194	a g-specific adenine glycosylase
WP9W18E04_36800	COG0617	tRNA 3'-terminal CCA addition
WP9W18E04_36840	COG3068	Protein conserved in bacteria
WP9W18E04_36860	COG0739	heme binding
WP9W18E04_36900	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WP9W18E04_36910	COG1121	(ABC) transporter
WP9W18E04_36920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WP9W18E04_36930	COG0583	DNA-binding transcription factor activity
WP9W18E04_36940	COG0697	spore germination
WP9W18E04_36950	COG1573	uracil-dna glycosylase
WP9W18E04_36980	COG2827	Endonuclease containing a URI domain
WP9W18E04_37010	COG1842	Phage shock protein A
WP9W18E04_37020	COG0204	Acyl-transferase
WP9W18E04_37060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WP9W18E04_37070	COG0484	heat shock protein binding
WP9W18E04_37110	COG4221	oxidoreductase activity
WP9W18E04_37180	COG3150	esterase
WP9W18E04_37200	COG3151	Protein conserved in bacteria
WP9W18E04_37210	COG0494	nUDIX hydrolase
WP9W18E04_37220	COG1538	Outer membrane efflux protein
WP9W18E04_37230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WP9W18E04_37230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WP9W18E04_37240	COG1560	Kdo2-lipid A biosynthetic process
WP9W18E04_37250	COG2213	PTS system mannitol-specific
WP9W18E04_37250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_37260	COG0246	Mannitol dehydrogenase
WP9W18E04_37270	COG3722	fumarate hydratase activity
WP9W18E04_37340	COG1671	Belongs to the UPF0178 family
WP9W18E04_37350	COG1988	membrane-bound metal-dependent
WP9W18E04_37360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WP9W18E04_37370	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_37410	COG1575	Belongs to the MenA family. Type 1 subfamily
WP9W18E04_37420	COG1169	isochorismate synthase
WP9W18E04_37430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WP9W18E04_37450	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WP9W18E04_37460	COG1441	menaquinone biosynthetic process
WP9W18E04_37470	COG0318	PFAM AMP-dependent synthetase and ligase
WP9W18E04_37480	COG3291	Pkd domain containing protein
WP9W18E04_37490	COG2949	membrane
WP9W18E04_37500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
WP9W18E04_37520	COG0835	chemotaxis
WP9W18E04_37520	COG0784	Response regulator, receiver
WP9W18E04_37540	COG1444	tRNA N-acetyltransferase activity
WP9W18E04_37580	COG1803	Methylglyoxal synthase
WP9W18E04_37590	COG1979	alcohol dehydrogenase
WP9W18E04_37630	COG4221	oxidoreductase activity
WP9W18E04_37700	COG1368	sulfuric ester hydrolase activity
WP9W18E04_37710	COG1522	sequence-specific DNA binding
WP9W18E04_37730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
WP9W18E04_37750	COG1546	Belongs to the CinA family
WP9W18E04_37750	COG1058	Belongs to the CinA family
WP9W18E04_37770	COG0561	phosphatase activity
WP9W18E04_37790	COG2926	Belongs to the UPF0265 family
WP9W18E04_37800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WP9W18E04_37810	COG0564	pseudouridine synthase activity
WP9W18E04_37830	COG0110	maltose O-acetyltransferase activity
WP9W18E04_37840	COG0366	Alpha amylase catalytic
WP9W18E04_37850	COG1263	PTS System
WP9W18E04_37850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WP9W18E04_37890	COG0252	asparaginase activity
WP9W18E04_37900	COG1253	flavin adenine dinucleotide binding
WP9W18E04_37910	COG0586	Pfam SNARE associated Golgi protein
WP9W18E04_37920	COG1686	Belongs to the peptidase S11 family
WP9W18E04_37930	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WP9W18E04_37950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WP9W18E04_37970	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WP9W18E04_37980	COG1546	Belongs to the CinA family
WP9W18E04_37990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WP9W18E04_38000	COG4667	esterase of the alpha-beta hydrolase superfamily
WP9W18E04_38030	COG1346	cytolysis
WP9W18E04_38040	COG1380	Effector of murein hydrolase LrgA
WP9W18E04_38050	COG0583	DNA-binding transcription factor activity
WP9W18E04_38090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
WP9W18E04_38110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WP9W18E04_38130	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WP9W18E04_38140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WP9W18E04_38160	COG0137	argininosuccinate synthase activity
WP9W18E04_38170	COG0165	Argininosuccinate lyase
WP9W18E04_38190	COG2226	methyltransferase
WP9W18E04_38250	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WP9W18E04_38260	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WP9W18E04_38290	COG0477	Major facilitator Superfamily
WP9W18E04_38300	COG0523	cobalamin synthesis protein
WP9W18E04_38320	COG2200	EAL domain
WP9W18E04_38330	COG1049	propionate catabolic process, 2-methylcitrate cycle
WP9W18E04_38340	COG1752	Esterase of the alpha-beta hydrolase superfamily
WP9W18E04_38350	COG0840	transmembrane signaling receptor activity
WP9W18E04_38370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WP9W18E04_38380	COG0508	dehydrogenase complex catalyzes the overall conversion of
WP9W18E04_38390	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WP9W18E04_38400	COG2186	Transcriptional regulator
WP9W18E04_38450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WP9W18E04_38460	COG1459	type II secretion system
WP9W18E04_38490	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WP9W18E04_38500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WP9W18E04_38510	COG0494	nUDIX hydrolase
WP9W18E04_38520	COG0653	protein targeting
WP9W18E04_38540	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WP9W18E04_38550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WP9W18E04_38560	COG0849	cell division
WP9W18E04_38580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WP9W18E04_38590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WP9W18E04_38600	COG0772	Belongs to the SEDS family
WP9W18E04_38620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
WP9W18E04_38630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WP9W18E04_38640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WP9W18E04_38660	COG0768	penicillin binding
WP9W18E04_38670	COG3116	cell division
WP9W18E04_38680	COG0275	rRNA processing
WP9W18E04_38690	COG2001	Belongs to the MraZ family
WP9W18E04_38700	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WP9W18E04_38710	COG3107	peptidoglycan biosynthetic process
WP9W18E04_38720	COG0792	nuclease activity
WP9W18E04_38730	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WP9W18E04_38750	COG2969	positive regulation of protein catabolic process
WP9W18E04_38760	COG0625	glutathione transferase activity
WP9W18E04_38770	COG2857	Cytochrome c1
WP9W18E04_38780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WP9W18E04_38790	COG0723	plastoquinol--plastocyanin reductase activity
WP9W18E04_38800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WP9W18E04_38810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WP9W18E04_38820	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WP9W18E04_38840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP9W18E04_38850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WP9W18E04_38860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_38870	COG1660	Displays ATPase and GTPase activities
WP9W18E04_38880	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WP9W18E04_38900	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WP9W18E04_38910	COG1137	ATPase activity
WP9W18E04_38920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WP9W18E04_38930	COG3117	lipopolysaccharide transmembrane transporter activity
WP9W18E04_38940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WP9W18E04_38950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WP9W18E04_38950	COG0517	IMP dehydrogenase activity
WP9W18E04_38960	COG1127	ABC transporter
WP9W18E04_38970	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WP9W18E04_38980	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WP9W18E04_38990	COG2854	intermembrane phospholipid transfer
WP9W18E04_39010	COG5007	Belongs to the BolA IbaG family
WP9W18E04_39020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WP9W18E04_39030	COG0312	modulator of DNA gyrase
WP9W18E04_39040	COG3028	Belongs to the UPF0307 family
WP9W18E04_39050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WP9W18E04_39090	COG1011	Hydrolase
WP9W18E04_39120	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WP9W18E04_39130	COG0019	diaminopimelate decarboxylase activity
WP9W18E04_39140	COG1965	Belongs to the frataxin family
WP9W18E04_39150	COG0400	carboxylic ester hydrolase activity
WP9W18E04_39160	COG3072	Adenylate cyclase
WP9W18E04_39170	COG0181	hydroxymethylbilane synthase activity
WP9W18E04_39190	COG2959	enzyme of heme biosynthesis
WP9W18E04_39220	COG1494	fructose-1,6-bisphosphatase
WP9W18E04_39330	COG0795	lipopolysaccharide-transporting ATPase activity
WP9W18E04_39350	COG0795	lipopolysaccharide-transporting ATPase activity
WP9W18E04_39360	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WP9W18E04_39370	COG2927	DNA polymerase III (CHI subunit)
WP9W18E04_39420	COG0454	-acetyltransferase
WP9W18E04_39420	COG0456	acetyltransferase
WP9W18E04_39430	COG0753	catalase activity
WP9W18E04_39480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WP9W18E04_39490	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
WP9W18E04_39500	COG5380	lipid catabolic process
WP9W18E04_39540	COG4533	DNA binding
WP9W18E04_39560	COG2873	o-acetylhomoserine
WP9W18E04_39620	COG3842	ATPase activity
WP9W18E04_39640	COG1175	transmembrane transport
WP9W18E04_39690	COG3069	C4-dicarboxylate transmembrane transporter activity
WP9W18E04_39730	COG2801	Transposase and inactivated derivatives
WP9W18E04_39740	COG2199	diguanylate cyclase activity
WP9W18E04_39740	COG2203	Gaf domain
WP9W18E04_39780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WP9W18E04_39790	COG1074	ATP-dependent DNA helicase activity
WP9W18E04_39800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WP9W18E04_39810	COG2259	Doxx family
WP9W18E04_39820	COG1741	Belongs to the pirin family
WP9W18E04_39840	COG0583	DNA-binding transcription factor activity
WP9W18E04_39880	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_39900	COG3706	GGDEF domain
WP9W18E04_39910	COG4771	TonB-dependent receptor
WP9W18E04_39920	COG4584	PFAM Integrase catalytic
WP9W18E04_39930	COG1484	DNA-dependent DNA replication
WP9W18E04_39950	COG0203	ribosomal protein L17
WP9W18E04_39960	COG0202	RNA polymerase activity
WP9W18E04_39970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WP9W18E04_39980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WP9W18E04_39990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WP9W18E04_40000	COG0201	protein transport
WP9W18E04_40010	COG0200	Binds to the 23S rRNA
WP9W18E04_40020	COG1841	ribosomal large subunit assembly
WP9W18E04_40030	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WP9W18E04_40040	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WP9W18E04_40050	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WP9W18E04_40060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WP9W18E04_40070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WP9W18E04_40080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WP9W18E04_40090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WP9W18E04_40100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WP9W18E04_40110	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WP9W18E04_40120	COG0255	Belongs to the universal ribosomal protein uL29 family
WP9W18E04_40130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WP9W18E04_40140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WP9W18E04_40150	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WP9W18E04_40160	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WP9W18E04_40170	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WP9W18E04_40180	COG0089	rRNA binding
WP9W18E04_40190	COG0088	Forms part of the polypeptide exit tunnel
WP9W18E04_40200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WP9W18E04_40210	COG0051	transcription antitermination factor activity, RNA binding
WP9W18E04_40240	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_40250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WP9W18E04_40260	COG2183	response to ionizing radiation
WP9W18E04_40300	COG0596	Alpha beta hydrolase
WP9W18E04_40310	COG1040	competence protein
WP9W18E04_40320	COG0316	Belongs to the HesB IscA family
WP9W18E04_40320	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WP9W18E04_40330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WP9W18E04_40340	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WP9W18E04_40350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP9W18E04_40360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WP9W18E04_40370	COG4942	peptidase
WP9W18E04_40390	COG1609	Transcriptional regulator
WP9W18E04_40400	COG0800	Aldolase
WP9W18E04_40410	COG0129	dihydroxy-acid dehydratase activity
WP9W18E04_40420	COG3265	gluconokinase activity
WP9W18E04_40430	COG2610	gluconate transmembrane transporter activity
WP9W18E04_40440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WP9W18E04_40450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WP9W18E04_40470	COG0456	acetyltransferase
WP9W18E04_40490	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
WP9W18E04_40500	COG1490	D-aminoacyl-tRNA deacylase activity
WP9W18E04_40510	COG1295	ribonuclease BN
WP9W18E04_40520	COG0281	malic enzyme
WP9W18E04_40530	COG0814	amino acid
WP9W18E04_40540	COG0702	epimerase
WP9W18E04_40560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WP9W18E04_40570	COG0254	rRNA binding
WP9W18E04_40600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WP9W18E04_40610	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WP9W18E04_40630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WP9W18E04_40650	COG0514	ATP-dependent DNA helicase (RecQ)
WP9W18E04_40660	COG0514	ATP-dependent DNA helicase (RecQ)
WP9W18E04_40670	COG2050	protein possibly involved in aromatic compounds catabolism
WP9W18E04_40690	COG2258	MOSC domain
WP9W18E04_40700	COG1177	transmembrane transport
WP9W18E04_40710	COG1176	ABC-type spermidine putrescine transport system, permease component I
WP9W18E04_40720	COG3842	ATPase activity
WP9W18E04_40760	COG0174	glutamine synthetase
WP9W18E04_40800	COG3045	CreA protein
WP9W18E04_40810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WP9W18E04_40820	COG0443	Heat shock 70 kDa protein
WP9W18E04_40850	COG0366	Alpha amylase catalytic
WP9W18E04_40880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WP9W18E04_40900	COG4211	Belongs to the binding-protein-dependent transport system permease family
WP9W18E04_40930	COG3250	beta-galactosidase activity
WP9W18E04_40940	COG1609	Transcriptional regulator
WP9W18E04_40950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WP9W18E04_40960	COG1085	galactose-1-phosphate uridylyltransferase
WP9W18E04_40970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WP9W18E04_40980	COG2017	converts alpha-aldose to the beta-anomer
WP9W18E04_40990	COG1968	undecaprenyl-diphosphatase activity
WP9W18E04_41010	COG1595	DNA-templated transcription, initiation
WP9W18E04_41030	COG0018	arginyl-trna synthetase
WP9W18E04_41050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WP9W18E04_41060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WP9W18E04_41080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WP9W18E04_41090	COG1131	(ABC) transporter
WP9W18E04_41100	COG0842	Transport permease protein
WP9W18E04_41110	COG0842	Transport permease protein
WP9W18E04_41120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WP9W18E04_41140	COG2116	formate transmembrane transporter activity
WP9W18E04_41150	COG1648	precorrin-2 dehydrogenase activity
WP9W18E04_41150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WP9W18E04_41160	COG2239	Acts as a magnesium transporter
WP9W18E04_41210	COG0210	DNA helicase
WP9W18E04_41220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WP9W18E04_41310	COG1280	lysine exporter protein (LysE YggA)
WP9W18E04_41370	COG3307	-O-antigen
WP9W18E04_41390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WP9W18E04_41420	COG1063	alcohol dehydrogenase
WP9W18E04_41430	COG3245	cytochrome
WP9W18E04_41460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WP9W18E04_41470	COG2166	iron-sulfur cluster assembly
WP9W18E04_41480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WP9W18E04_41500	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
WP9W18E04_41510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WP9W18E04_41520	COG1739	Uncharacterized protein family UPF0029
WP9W18E04_41530	COG0006	proline dipeptidase activity
WP9W18E04_41540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WP9W18E04_41550	COG1250	3-hydroxyacyl-CoA dehydrogenase
WP9W18E04_41550	COG1024	Enoyl-CoA hydratase
WP9W18E04_41560	COG0183	Belongs to the thiolase family
WP9W18E04_41570	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_41580	COG2205	protein histidine kinase activity
WP9W18E04_41610	COG0425	Belongs to the sulfur carrier protein TusA family
WP9W18E04_41620	COG0251	oxidation-reduction process
WP9W18E04_41630	COG2885	chlorophyll binding
WP9W18E04_41660	COG2818	Glycosylase
WP9W18E04_41670	COG0752	glycyl-tRNA synthetase alpha subunit
WP9W18E04_41680	COG0751	glycine-tRNA ligase activity
WP9W18E04_41760	COG1609	Transcriptional regulator
WP9W18E04_41830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WP9W18E04_41860	COG2960	long-chain fatty acid transporting porin activity
WP9W18E04_41870	COG5002	protein histidine kinase activity
WP9W18E04_41870	COG5001	Diguanylate cyclase
WP9W18E04_41890	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WP9W18E04_41920	COG3118	belongs to the thioredoxin family
WP9W18E04_41930	COG0513	Belongs to the DEAD box helicase family
WP9W18E04_41940	COG0248	Ppx GppA phosphatase
WP9W18E04_41960	COG0742	ribosomal rna small subunit methyltransferase
WP9W18E04_41990	COG3469	chitinase activity
WP9W18E04_42010	COG0084	hydrolase, TatD family'
WP9W18E04_42020	COG0805	protein transport
WP9W18E04_42030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP9W18E04_42040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WP9W18E04_42050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WP9W18E04_42060	COG3165	ubiquinone biosynthetic process from chorismate
WP9W18E04_42070	COG2226	methyltransferase
WP9W18E04_42080	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WP9W18E04_42090	COG0402	S-adenosylhomocysteine deaminase activity
WP9W18E04_42100	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WP9W18E04_42130	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
WP9W18E04_42140	COG0848	biopolymer transport protein
WP9W18E04_42150	COG0811	peptide transport
WP9W18E04_42160	COG0811	peptide transport
WP9W18E04_42180	COG2771	luxR family
WP9W18E04_42190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
WP9W18E04_42200	COG1349	DNA-binding transcription factor activity
WP9W18E04_42210	COG0745	RESPONSE REGULATOR receiver
WP9W18E04_42220	COG2205	protein histidine kinase activity
WP9W18E04_42250	COG4452	Inner membrane protein CreD
WP9W18E04_42260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WP9W18E04_42270	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WP9W18E04_42280	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WP9W18E04_42290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WP9W18E04_42300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WP9W18E04_42310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WP9W18E04_42320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WP9W18E04_42340	COG0356	it plays a direct role in the translocation of protons across the membrane
WP9W18E04_42360	COG1475	DNA binding
WP9W18E04_42370	COG1192	Involved in chromosome partitioning
WP9W18E04_42380	COG0357	Ribosomal RNA small subunit methyltransferase G
WP9W18E04_42390	COG0445	tRNA wobble uridine modification
WP9W18E04_42400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WP9W18E04_42410	COG4774	siderophore transport
WP9W18E04_42420	COG4615	Cyclic peptide transporter
WP9W18E04_42430	COG1120	ATPase activity
WP9W18E04_42440	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WP9W18E04_42460	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WP9W18E04_42470	COG0706	membrane insertase activity
WP9W18E04_42480	COG0594	ribonuclease P activity
WP9W18E04_42490	COG0230	Belongs to the bacterial ribosomal protein bL34 family
WP9W18E04_P10010	COG4584	PFAM Integrase catalytic
WP9W18E04_P10020	COG1484	DNA-dependent DNA replication
WP9W18E04_P10030	COG2132	Multicopper oxidase
WP9W18E04_P10060	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
WP9W18E04_P10140	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP9W18E04_P10160	COG1230	cation diffusion facilitator family transporter
WP9W18E04_P10170	COG1937	Protein conserved in bacteria
WP9W18E04_P10180	COG2814	Major facilitator Superfamily
WP9W18E04_P10240	COG1238	metal cluster binding
WP9W18E04_P10330	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
WP9W18E04_P10390	COG4644	lycopene metabolic process
WP9W18E04_P10410	COG1192	Involved in chromosome partitioning
WP9W18E04_P10430	COG2916	Histone family protein nucleoid-structuring protein H-NS
WP9W18E04_P10510	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WP9W18E04_P10530	COG4804	nuclease activity
WP9W18E04_P10540	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
WP9W18E04_P10570	COG4584	PFAM Integrase catalytic
WP9W18E04_P10580	COG1484	DNA-dependent DNA replication
WP9W18E04_P10660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
WP9W18E04_P10760	COG2003	Belongs to the UPF0758 family
WP9W18E04_P11120	COG3385	transposase activity
WP9W18E04_P11150	COG2801	Transposase and inactivated derivatives
WP9W18E04_P11220	COG3039	Transposase
WP9W18E04_P11290	COG1028	Short-chain dehydrogenase reductase Sdr
WP9W18E04_P11310	COG1349	DNA-binding transcription factor activity