locus-tag	class	description
CVS41_00015	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CVS41_00020	COG0848	biopolymer transport protein
CVS41_00025	COG0811	peptide transport
CVS41_00030	COG0811	peptide transport
CVS41_00040	COG2771	luxR family
CVS41_00045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CVS41_00050	COG1349	DNA-binding transcription factor activity
CVS41_00055	COG0745	RESPONSE REGULATOR receiver
CVS41_00060	COG2205	protein histidine kinase activity
CVS41_00075	COG4452	Inner membrane protein CreD
CVS41_00090	COG0438	transferase activity, transferring glycosyl groups
CVS41_00090	COG0297	glycogen (starch) synthase activity
CVS41_00135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CVS41_00140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CVS41_00145	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CVS41_00150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CVS41_00155	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CVS41_00160	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CVS41_00165	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CVS41_00170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CVS41_00180	COG0356	it plays a direct role in the translocation of protons across the membrane
CVS41_00190	COG1475	DNA binding
CVS41_00195	COG1192	Involved in chromosome partitioning
CVS41_00200	COG0357	Ribosomal RNA small subunit methyltransferase G
CVS41_00205	COG0445	tRNA wobble uridine modification
CVS41_00210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CVS41_00220	COG4615	Cyclic peptide transporter
CVS41_00225	COG1120	ATPase activity
CVS41_00230	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CVS41_00240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CVS41_00245	COG0706	membrane insertase activity
CVS41_00250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CVS41_00255	COG0594	ribonuclease P activity
CVS41_00260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CVS41_00280	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CVS41_00285	COG0592	DNA-directed DNA polymerase activity
CVS41_00295	COG0187	DNA topoisomerase II activity
CVS41_00315	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CVS41_00320	COG0071	Belongs to the small heat shock protein (HSP20) family
CVS41_00325	COG0071	Belongs to the small heat shock protein (HSP20) family
CVS41_00330	COG3977	Valine--pyruvate aminotransferase
CVS41_00345	COG2814	Major facilitator Superfamily
CVS41_00350	COG0745	RESPONSE REGULATOR receiver
CVS41_00355	COG2205	protein histidine kinase activity
CVS41_00380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVS41_00385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_00385	COG4191	Histidine kinase
CVS41_00390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_00395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_00400	COG1309	transcriptional regulator
CVS41_00430	COG0561	phosphatase activity
CVS41_00435	COG2267	carboxylic ester hydrolase activity
CVS41_00440	COG0110	maltose O-acetyltransferase activity
CVS41_00445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVS41_00450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CVS41_00455	COG1758	RNA polymerase activity
CVS41_00460	COG0194	GDP metabolic process
CVS41_00470	COG0859	PFAM glycosyl transferase family 9
CVS41_00475	COG3642	lipopolysaccharide core region biosynthetic process
CVS41_00515	COG0589	response to stress
CVS41_00525	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CVS41_00530	COG1528	Iron-storage protein
CVS41_00535	COG2081	HI0933 family
CVS41_00540	COG3275	phosphorelay sensor kinase activity
CVS41_00545	COG3279	Response regulator of the LytR AlgR family
CVS41_00550	COG2223	nitrite transmembrane transporter activity
CVS41_00555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CVS41_00560	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CVS41_00575	COG0583	DNA-binding transcription factor activity
CVS41_00585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CVS41_00615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CVS41_00620	COG2166	iron-sulfur cluster assembly
CVS41_00625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CVS41_00640	COG3245	cytochrome
CVS41_00645	COG1063	alcohol dehydrogenase
CVS41_00660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVS41_00705	COG1280	lysine exporter protein (LysE YggA)
CVS41_00755	COG0210	DNA helicase
CVS41_00770	COG0840	transmembrane signaling receptor activity
CVS41_00800	COG0737	Belongs to the 5'-nucleotidase family
CVS41_00810	COG2239	Acts as a magnesium transporter
CVS41_00815	COG1648	precorrin-2 dehydrogenase activity
CVS41_00815	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVS41_00820	COG2116	formate transmembrane transporter activity
CVS41_00825	COG2146	nitrite reductase [NAD(P)H] activity
CVS41_00830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVS41_00835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CVS41_00840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CVS41_00850	COG0018	arginyl-trna synthetase
CVS41_00860	COG1595	DNA-templated transcription, initiation
CVS41_00870	COG1968	undecaprenyl-diphosphatase activity
CVS41_00875	COG2017	converts alpha-aldose to the beta-anomer
CVS41_00880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVS41_00885	COG1085	galactose-1-phosphate uridylyltransferase
CVS41_00890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVS41_00895	COG1609	Transcriptional regulator
CVS41_00900	COG3250	beta-galactosidase activity
CVS41_00910	COG1129	ABC transporter
CVS41_00915	COG4211	Belongs to the binding-protein-dependent transport system permease family
CVS41_00925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVS41_00940	COG0366	Alpha amylase catalytic
CVS41_00955	COG0443	Heat shock 70 kDa protein
CVS41_00960	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CVS41_00965	COG3045	CreA protein
CVS41_00980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CVS41_00985	COG0174	glutamine synthetase
CVS41_01005	COG3842	ATPase activity
CVS41_01010	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVS41_01015	COG1177	transmembrane transport
CVS41_01020	COG2258	MOSC domain
CVS41_01035	COG2050	protein possibly involved in aromatic compounds catabolism
CVS41_01040	COG0514	ATP-dependent DNA helicase (RecQ)
CVS41_01050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CVS41_01060	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CVS41_01065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CVS41_01080	COG0254	rRNA binding
CVS41_01085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CVS41_01095	COG0702	epimerase
CVS41_01100	COG0814	amino acid
CVS41_01105	COG0281	malic enzyme
CVS41_01110	COG1295	ribonuclease BN
CVS41_01115	COG1490	D-aminoacyl-tRNA deacylase activity
CVS41_01120	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CVS41_01125	COG0456	acetyltransferase
CVS41_01135	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CVS41_01140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CVS41_01145	COG2610	gluconate transmembrane transporter activity
CVS41_01150	COG3265	gluconokinase activity
CVS41_01155	COG0129	dihydroxy-acid dehydratase activity
CVS41_01160	COG0800	Aldolase
CVS41_01165	COG1609	Transcriptional regulator
CVS41_01175	COG4942	peptidase
CVS41_01180	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CVS41_01185	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVS41_01190	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CVS41_01195	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CVS41_01200	COG0316	Belongs to the HesB IscA family
CVS41_01200	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CVS41_01205	COG1040	competence protein
CVS41_01210	COG0596	Alpha beta hydrolase
CVS41_01230	COG2183	response to ionizing radiation
CVS41_01235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVS41_01240	COG0745	RESPONSE REGULATOR receiver
CVS41_01255	COG0051	transcription antitermination factor activity, RNA binding
CVS41_01260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CVS41_01265	COG0088	Forms part of the polypeptide exit tunnel
CVS41_01270	COG0089	rRNA binding
CVS41_01275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CVS41_01280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CVS41_01285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CVS41_01290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CVS41_01295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CVS41_01300	COG0255	Belongs to the universal ribosomal protein uL29 family
CVS41_01305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CVS41_01310	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CVS41_01315	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CVS41_01320	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CVS41_01325	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CVS41_01330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CVS41_01335	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CVS41_01340	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CVS41_01345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CVS41_01350	COG1841	ribosomal large subunit assembly
CVS41_01355	COG0200	Binds to the 23S rRNA
CVS41_01360	COG0201	protein transport
CVS41_01365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CVS41_01370	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CVS41_01375	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CVS41_01380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CVS41_01385	COG0202	RNA polymerase activity
CVS41_01390	COG0203	ribosomal protein L17
CVS41_01440	COG4771	TonB-dependent receptor
CVS41_01445	COG3706	GGDEF domain
CVS41_01455	COG0745	RESPONSE REGULATOR receiver
CVS41_01470	COG0583	DNA-binding transcription factor activity
CVS41_01480	COG1741	Belongs to the pirin family
CVS41_01485	COG2259	Doxx family
CVS41_01490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CVS41_01495	COG1074	ATP-dependent DNA helicase activity
CVS41_01500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CVS41_01515	COG3706	GGDEF domain
CVS41_01545	COG1175	transmembrane transport
CVS41_01555	COG3842	ATPase activity
CVS41_01585	COG2873	o-acetylhomoserine
CVS41_01595	COG4533	DNA binding
CVS41_01600	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CVS41_01615	COG5380	lipid catabolic process
CVS41_01620	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CVS41_01625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CVS41_01650	COG0753	catalase activity
CVS41_01655	COG0456	acetyltransferase
CVS41_01655	COG0454	-acetyltransferase
CVS41_01680	COG2927	DNA polymerase III (CHI subunit)
CVS41_01685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CVS41_01690	COG0795	lipopolysaccharide-transporting ATPase activity
CVS41_01695	COG0795	lipopolysaccharide-transporting ATPase activity
CVS41_01710	COG0582	viral genome integration into host DNA
CVS41_01755	COG4584	PFAM Integrase catalytic
CVS41_01760	COG1484	DNA-dependent DNA replication
CVS41_01795	COG2211	Major facilitator Superfamily
CVS41_01805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVS41_01815	COG1879	ABC-type sugar transport system periplasmic component
CVS41_01820	COG1069	ribulokinase activity
CVS41_01830	COG2160	L-arabinose isomerase activity
CVS41_01835	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVS41_01840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CVS41_01855	COG2017	converts alpha-aldose to the beta-anomer
CVS41_01880	COG0531	amino acid
CVS41_01900	COG1494	fructose-1,6-bisphosphatase
CVS41_01915	COG2959	enzyme of heme biosynthesis
CVS41_01925	COG0181	hydroxymethylbilane synthase activity
CVS41_01930	COG3072	Adenylate cyclase
CVS41_01935	COG0400	carboxylic ester hydrolase activity
CVS41_01940	COG1965	Belongs to the frataxin family
CVS41_01950	COG0019	diaminopimelate decarboxylase activity
CVS41_01955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CVS41_01970	COG1011	Hydrolase
CVS41_01990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CVS41_01995	COG3028	Belongs to the UPF0307 family
CVS41_02000	COG0312	modulator of DNA gyrase
CVS41_02005	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CVS41_02010	COG5007	Belongs to the BolA IbaG family
CVS41_02020	COG2854	intermembrane phospholipid transfer
CVS41_02025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVS41_02030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CVS41_02035	COG1127	ABC transporter
CVS41_02040	COG0517	IMP dehydrogenase activity
CVS41_02040	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CVS41_02045	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CVS41_02050	COG3117	lipopolysaccharide transmembrane transporter activity
CVS41_02055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CVS41_02060	COG1137	ATPase activity
CVS41_02075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_02080	COG1660	Displays ATPase and GTPase activities
CVS41_02085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_02090	COG3711	transcriptional antiterminator
CVS41_02090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_02105	COG3964	amidohydrolase
CVS41_02135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVS41_02140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CVS41_02150	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CVS41_02155	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CVS41_02160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CVS41_02165	COG0723	plastoquinol--plastocyanin reductase activity
CVS41_02170	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CVS41_02175	COG2857	Cytochrome c1
CVS41_02180	COG0625	glutathione transferase activity
CVS41_02185	COG2969	positive regulation of protein catabolic process
CVS41_02190	COG2823	Periplasmic or secreted lipoprotein
CVS41_02195	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CVS41_02200	COG0792	nuclease activity
CVS41_02205	COG3107	peptidoglycan biosynthetic process
CVS41_02210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CVS41_02220	COG2001	Belongs to the MraZ family
CVS41_02225	COG0275	rRNA processing
CVS41_02230	COG3116	cell division
CVS41_02235	COG0768	penicillin binding
CVS41_02245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CVS41_02250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVS41_02255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CVS41_02260	COG0772	Belongs to the SEDS family
CVS41_02265	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CVS41_02270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CVS41_02280	COG0849	cell division
CVS41_02285	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CVS41_02290	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CVS41_02300	COG0653	protein targeting
CVS41_02305	COG0494	nUDIX hydrolase
CVS41_02310	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CVS41_02315	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CVS41_02330	COG1459	type II secretion system
CVS41_02335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVS41_02365	COG2186	Transcriptional regulator
CVS41_02370	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CVS41_02375	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVS41_02380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CVS41_02390	COG0840	transmembrane signaling receptor activity
CVS41_02395	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVS41_02400	COG1049	propionate catabolic process, 2-methylcitrate cycle
CVS41_02405	COG2200	EAL domain
CVS41_02415	COG0523	cobalamin synthesis protein
CVS41_02420	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_02435	COG0477	Major facilitator Superfamily
CVS41_02450	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CVS41_02455	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CVS41_02500	COG0165	Argininosuccinate lyase
CVS41_02505	COG0137	argininosuccinate synthase activity
CVS41_02515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CVS41_02520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CVS41_02530	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CVS41_02545	COG3706	GGDEF domain
CVS41_02550	COG0814	amino acid
CVS41_02555	COG3932	Exopolysaccharide synthesis, ExoD
CVS41_02565	COG3706	GGDEF domain
CVS41_02570	COG0004	ammonium transporteR
CVS41_02575	COG3133	Outer membrane lipoprotein
CVS41_02580	COG0456	acetyltransferase
CVS41_02605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CVS41_02620	COG0671	phosphoesterase, PA-phosphatase related
CVS41_02625	COG0628	permease
CVS41_02640	COG3284	Transcriptional regulator
CVS41_02650	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CVS41_02650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CVS41_02650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_02655	COG1461	Dihydroxyacetone kinase
CVS41_02660	COG2376	Dihydroxyacetone kinase
CVS41_02665	COG2252	PERMEase
CVS41_02670	COG1278	Cold shock
CVS41_02680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CVS41_02700	COG2197	response regulator
CVS41_02715	COG1462	curli production assembly transport component CsgG
CVS41_02735	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CVS41_02740	COG3706	GGDEF domain
CVS41_02745	COG3047	cAMP biosynthetic process
CVS41_02750	COG0840	transmembrane signaling receptor activity
CVS41_02780	COG1396	sequence-specific DNA binding
CVS41_02820	COG2926	Belongs to the UPF0265 family
CVS41_02830	COG0561	phosphatase activity
CVS41_02840	COG1058	Belongs to the CinA family
CVS41_02840	COG1546	Belongs to the CinA family
CVS41_02850	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CVS41_02860	COG1522	sequence-specific DNA binding
CVS41_02865	COG1368	sulfuric ester hydrolase activity
CVS41_02900	COG4221	oxidoreductase activity
CVS41_02915	COG1979	alcohol dehydrogenase
CVS41_02920	COG1803	Methylglyoxal synthase
CVS41_02940	COG1444	tRNA N-acetyltransferase activity
CVS41_02945	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_02950	COG0835	chemotaxis
CVS41_02950	COG0784	Response regulator, receiver
CVS41_02960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CVS41_02965	COG2949	membrane
CVS41_02970	COG3291	Pkd domain containing protein
CVS41_02975	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_02980	COG1441	menaquinone biosynthetic process
CVS41_02985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CVS41_02990	COG0596	Alpha beta hydrolase
CVS41_02995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CVS41_03000	COG1169	isochorismate synthase
CVS41_03005	COG1575	Belongs to the MenA family. Type 1 subfamily
CVS41_03025	COG0513	Belongs to the DEAD box helicase family
CVS41_03030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_03035	COG1988	membrane-bound metal-dependent
CVS41_03040	COG1671	Belongs to the UPF0178 family
CVS41_03060	COG0484	heat shock protein binding
CVS41_03070	COG3722	fumarate hydratase activity
CVS41_03075	COG0246	Mannitol dehydrogenase
CVS41_03080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_03080	COG2213	PTS system mannitol-specific
CVS41_03085	COG1560	Kdo2-lipid A biosynthetic process
CVS41_03090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CVS41_03090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CVS41_03095	COG1538	Outer membrane efflux protein
CVS41_03100	COG0494	nUDIX hydrolase
CVS41_03105	COG3151	Protein conserved in bacteria
CVS41_03115	COG3150	esterase
CVS41_03120	COG0187	DNA topoisomerase II activity
CVS41_03135	COG3104	oligopeptide transport
CVS41_03165	COG2084	Dehydrogenase
CVS41_03170	COG0583	DNA-binding transcription factor activity
CVS41_03175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVS41_03195	COG0204	Acyl-transferase
CVS41_03200	COG1842	Phage shock protein A
CVS41_03215	COG2827	Endonuclease containing a URI domain
CVS41_03230	COG1573	uracil-dna glycosylase
CVS41_03235	COG0697	spore germination
CVS41_03240	COG0583	DNA-binding transcription factor activity
CVS41_03245	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CVS41_03250	COG1121	(ABC) transporter
CVS41_03255	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CVS41_03275	COG0739	heme binding
CVS41_03285	COG3068	Protein conserved in bacteria
CVS41_03305	COG0617	tRNA 3'-terminal CCA addition
CVS41_03310	COG1194	a g-specific adenine glycosylase
CVS41_03315	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CVS41_03325	COG3111	PFAM Bacterial OB fold (BOF) protein
CVS41_03330	COG3240	lipase activity
CVS41_03335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CVS41_03335	COG2885	chlorophyll binding
CVS41_03340	COG3706	GGDEF domain
CVS41_03345	COG0557	exoribonuclease II activity
CVS41_03350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CVS41_03360	COG2153	protein acetylation
CVS41_03365	COG0513	Belongs to the DEAD box helicase family
CVS41_03370	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CVS41_03395	COG0735	belongs to the Fur family
CVS41_03400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CVS41_03405	COG0840	transmembrane signaling receptor activity
CVS41_03415	COG4166	transmembrane transport
CVS41_03435	COG1024	Enoyl-CoA hydratase
CVS41_03450	COG4221	oxidoreductase activity
CVS41_03455	COG0442	prolyl-tRNA aminoacylation
CVS41_03460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVS41_03470	COG3008	intermembrane lipid transfer
CVS41_03470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CVS41_03475	COG2995	paraquat-inducible protein a
CVS41_03485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_03495	COG2203	Gaf domain
CVS41_03495	COG5001	Diguanylate cyclase
CVS41_03495	COG3706	GGDEF domain
CVS41_03495	COG4251	negative regulation of phosphorylation
CVS41_03500	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CVS41_03510	COG3916	Acyl-homoserine-lactone synthase
CVS41_03515	COG2771	luxR family
CVS41_03525	COG0840	transmembrane signaling receptor activity
CVS41_03530	COG0632	four-way junction helicase activity
CVS41_03535	COG2255	four-way junction helicase activity
CVS41_03545	COG1294	oxidase, subunit
CVS41_03550	COG4890	Cyd operon protein YbgT
CVS41_03555	COG3790	cyd operon protein YbgE
CVS41_03560	COG0824	Thioesterase
CVS41_03565	COG0811	peptide transport
CVS41_03580	COG0823	Involved in the tonB-independent uptake of proteins
CVS41_03585	COG2885	chlorophyll binding
CVS41_03590	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CVS41_03635	COG0733	neurotransmitter:sodium symporter activity
CVS41_03645	COG0733	neurotransmitter:sodium symporter activity
CVS41_03660	COG0561	phosphatase activity
CVS41_03675	COG1522	sequence-specific DNA binding
CVS41_03710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CVS41_03715	COG1640	4-alpha-glucanotransferase
CVS41_03725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CVS41_03730	COG0676	glucose-6-phosphate 1-epimerase activity
CVS41_03735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CVS41_03740	COG0840	transmembrane signaling receptor activity
CVS41_03745	COG1585	Membrane protein implicated in regulation of membrane protease activity
CVS41_03750	COG0330	HflC and HflK could
CVS41_03755	COG1648	precorrin-2 dehydrogenase activity
CVS41_03755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVS41_03760	COG0175	sulfate reduction
CVS41_03765	COG2895	sulfate adenylyltransferase (ATP) activity
CVS41_03770	COG3273	potassium ion transport
CVS41_03770	COG0471	metal ion transport
CVS41_03775	COG0529	Catalyzes the synthesis of activated sulfate
CVS41_03785	COG0840	transmembrane signaling receptor activity
CVS41_03820	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CVS41_03835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CVS41_03840	COG0784	Response regulator, receiver
CVS41_03840	COG3437	response regulator, receiver
CVS41_03850	COG2076	Multidrug Resistance protein
CVS41_03855	COG2076	Multidrug Resistance protein
CVS41_03860	COG0346	lactoylglutathione lyase activity
CVS41_03865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVS41_03870	COG1643	Atp-dependent helicase
CVS41_03880	COG1489	DNA binding
CVS41_03885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CVS41_03890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_03900	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CVS41_03905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CVS41_03910	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CVS41_03940	COG1924	4 iron, 4 sulfur cluster binding
CVS41_03945	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
CVS41_03950	COG0842	Transport permease protein
CVS41_03955	COG1131	(ABC) transporter
CVS41_03970	COG0163	prenyltransferase activity
CVS41_03975	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CVS41_03980	COG0671	phosphoesterase, PA-phosphatase related
CVS41_03985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVS41_03990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_03995	COG1151	hydroxylamine reductase activity
CVS41_04000	COG0783	Belongs to the Dps family
CVS41_04005	COG3023	N-Acetylmuramoyl-L-alanine amidase
CVS41_04010	COG4807	Protein conserved in bacteria
CVS41_04020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CVS41_04025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CVS41_04030	COG3956	TIGRFAM MazG family protein
CVS41_04035	COG0504	CTP synthase activity
CVS41_04040	COG0148	phosphopyruvate hydratase activity
CVS41_04095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CVS41_04105	COG0488	(ABC) transporter
CVS41_04125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVS41_04140	COG1794	racemase activity, acting on amino acids and derivatives
CVS41_04150	COG2731	YhcH YjgK YiaL family protein
CVS41_04160	COG0668	transmembrane transport
CVS41_04165	COG1376	ErfK ybiS ycfS ynhG family protein
CVS41_04175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVS41_04180	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CVS41_04185	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CVS41_04195	COG0585	pseudouridine synthase activity
CVS41_04200	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CVS41_04205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CVS41_04210	COG1238	metal cluster binding
CVS41_04225	COG1902	pentaerythritol trinitrate reductase activity
CVS41_04240	COG2957	Belongs to the agmatine deiminase family
CVS41_04245	COG0154	amidase activity
CVS41_04265	COG0513	Belongs to the DEAD box helicase family
CVS41_04270	COG2203	Gaf domain
CVS41_04270	COG2199	diguanylate cyclase activity
CVS41_04280	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CVS41_04285	COG1858	cytochrome C peroxidase
CVS41_04330	COG2816	NAD+ diphosphatase activity
CVS41_04340	COG4191	Histidine kinase
CVS41_04365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CVS41_04375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVS41_04380	COG4991	sh3 domain protein
CVS41_04390	COG2816	NAD+ diphosphatase activity
CVS41_04395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CVS41_04400	COG1940	carbohydrate kinase activity
CVS41_04405	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CVS41_04410	COG0126	phosphoglycerate kinase activity
CVS41_04415	COG0191	fructose-bisphosphate aldolase activity
CVS41_04420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_04465	COG0354	folic acid binding
CVS41_04470	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CVS41_04480	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CVS41_04485	COG1595	DNA-templated transcription, initiation
CVS41_04490	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CVS41_04495	COG3026	antisigma factor binding
CVS41_04505	COG0481	GTPase activity
CVS41_04510	COG0681	Belongs to the peptidase S26 family
CVS41_04525	COG1381	Involved in DNA repair and RecF pathway recombination
CVS41_04530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CVS41_04540	COG2350	Protein conserved in bacteria
CVS41_04545	COG2917	probably involved in intracellular septation
CVS41_04550	COG0076	glutamate decarboxylase activity
CVS41_04555	COG1272	protein, Hemolysin III
CVS41_04560	COG0569	domain protein
CVS41_04560	COG2985	domain, Protein
CVS41_04580	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
CVS41_04610	COG2313	pseudouridylate synthase activity
CVS41_04615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVS41_04650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVS41_04655	COG1765	OsmC-like protein
CVS41_04670	COG3954	Phosphoribulokinase
CVS41_04675	COG3089	Belongs to the UPF0270 family
CVS41_04680	COG4251	negative regulation of phosphorylation
CVS41_04680	COG3706	GGDEF domain
CVS41_04680	COG5001	Diguanylate cyclase
CVS41_04680	COG2203	Gaf domain
CVS41_04685	COG0429	hydrolase of the alpha beta-hydrolase fold
CVS41_04690	COG0784	Response regulator, receiver
CVS41_04690	COG0835	chemotaxis
CVS41_04700	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CVS41_04705	COG1047	Peptidyl-prolyl cis-trans
CVS41_04720	COG0305	Participates in initiation and elongation during chromosome replication
CVS41_04725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CVS41_04730	COG0432	Pfam Uncharacterised protein family UPF0047
CVS41_04735	COG3340	Belongs to the peptidase S51 family
CVS41_04750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_04760	COG3721	Heme iron utilization protein
CVS41_04765	COG0748	coenzyme F420 binding
CVS41_04790	COG2814	Major facilitator Superfamily
CVS41_04800	COG3655	Transcriptional regulator
CVS41_04810	COG0784	Response regulator, receiver
CVS41_04810	COG2205	protein histidine kinase activity
CVS41_04810	COG5002	protein histidine kinase activity
CVS41_04820	COG3706	GGDEF domain
CVS41_04880	COG0835	chemotaxis
CVS41_04880	COG0784	Response regulator, receiver
CVS41_04885	COG2755	lipolytic protein G-D-S-L family
CVS41_04890	COG4181	ATPase activity
CVS41_04895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CVS41_04900	COG1090	epimerase
CVS41_04905	COG2200	EAL domain
CVS41_04910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVS41_04915	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CVS41_04920	COG3171	Protein conserved in bacteria
CVS41_04925	COG2066	Belongs to the glutaminase family
CVS41_04930	COG2897	thiosulfate sulfurtransferase activity
CVS41_04945	COG0521	Mo-molybdopterin cofactor biosynthetic process
CVS41_04955	COG2966	Psort location CytoplasmicMembrane, score
CVS41_04960	COG3610	response to peptide
CVS41_04975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CVS41_04980	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CVS41_04990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CVS41_05005	COG0786	glutamate:sodium symporter activity
CVS41_05010	COG0252	asparaginase activity
CVS41_05015	COG3139	Protein of unknown function (DUF1315)
CVS41_05035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CVS41_05040	COG0321	lipoyl(octanoyl) transferase activity
CVS41_05045	COG2921	Belongs to the UPF0250 family
CVS41_05050	COG1686	Belongs to the peptidase S11 family
CVS41_05055	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CVS41_05060	COG2951	lytic endotransglycosylase activity
CVS41_05065	COG0772	Belongs to the SEDS family
CVS41_05070	COG0768	penicillin binding
CVS41_05075	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CVS41_05080	COG0799	negative regulation of ribosome biogenesis
CVS41_05085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CVS41_05100	COG0495	leucyl-tRNA aminoacylation
CVS41_05105	COG2888	peptidyl-tyrosine sulfation
CVS41_05110	COG0312	modulator of DNA gyrase
CVS41_05120	COG0716	FMN binding
CVS41_05125	COG4974	Belongs to the 'phage' integrase family
CVS41_05130	COG1970	mechanosensitive ion channel activity
CVS41_05145	COG0789	Transcriptional regulator
CVS41_05150	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CVS41_05155	COG4535	Mg2 and Co2 transporter CorC
CVS41_05160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CVS41_05165	COG1702	phosphate starvation-inducible protein PhoH
CVS41_05170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CVS41_05175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVS41_05180	COG1335	isochorismatase
CVS41_05185	COG3706	GGDEF domain
CVS41_05190	COG0583	DNA-binding transcription factor activity
CVS41_05210	COG3447	MASE1 domain protein
CVS41_05210	COG5002	protein histidine kinase activity
CVS41_05210	COG5001	Diguanylate cyclase
CVS41_05220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CVS41_05230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CVS41_05240	COG0516	GMP reductase activity
CVS41_05250	COG0642	Histidine kinase
CVS41_05255	COG0745	RESPONSE REGULATOR receiver
CVS41_05265	COG4221	oxidoreductase activity
CVS41_05275	COG1022	Amp-dependent synthetase and ligase
CVS41_05290	COG3214	Protein conserved in bacteria
CVS41_05300	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVS41_05305	COG0700	Nucleoside recognition
CVS41_05310	COG3366	ferrous iron transmembrane transporter activity
CVS41_05315	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CVS41_05320	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
CVS41_05325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CVS41_05330	COG1053	succinate dehydrogenase
CVS41_05340	COG0584	glycerophosphoryl diester phosphodiesterase
CVS41_05345	COG1511	domain protein
CVS41_05345	COG3264	Mechanosensitive ion channel
CVS41_05355	COG0739	heme binding
CVS41_05365	COG0583	DNA-binding transcription factor activity
CVS41_05385	COG0583	DNA-binding transcription factor activity
CVS41_05390	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CVS41_05420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CVS41_05425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CVS41_05435	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CVS41_05440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CVS41_05450	COG0180	Tryptophanyl-tRNA synthetase
CVS41_05460	COG0512	Glutamine amidotransferase of anthranilate synthase
CVS41_05465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CVS41_05475	COG1012	belongs to the aldehyde dehydrogenase family
CVS41_05490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_05500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_05500	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CVS41_05500	COG0674	pyruvate-flavodoxin oxidoreductase activity
CVS41_05500	COG1013	pyruvate-flavodoxin oxidoreductase activity
CVS41_05505	COG0366	Alpha amylase catalytic
CVS41_05530	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CVS41_05540	COG0490	domain, Protein
CVS41_05540	COG0471	metal ion transport
CVS41_05580	COG0012	GTP binding
CVS41_05585	COG0193	aminoacyl-tRNA hydrolase activity
CVS41_05590	COG0737	Belongs to the 5'-nucleotidase family
CVS41_05595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CVS41_05605	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CVS41_05610	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CVS41_05615	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CVS41_05620	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CVS41_05625	COG2890	protein-(glutamine-N5) methyltransferase activity
CVS41_05635	COG2912	Transglutaminase-like superfamily
CVS41_05640	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CVS41_05655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CVS41_05665	COG3408	Glycogen debranching enzyme
CVS41_05665	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
CVS41_05675	COG1881	PFAM PEBP family protein
CVS41_05695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CVS41_05705	COG0583	DNA-binding transcription factor activity
CVS41_05710	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_05715	COG0616	signal peptide processing
CVS41_05720	COG2211	Major facilitator Superfamily
CVS41_05725	COG3706	GGDEF domain
CVS41_05730	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CVS41_05740	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_05750	COG2199	diguanylate cyclase activity
CVS41_05750	COG2203	Gaf domain
CVS41_05750	COG2200	EAL domain
CVS41_05775	COG2197	response regulator
CVS41_05805	COG3724	N-succinylarginine dihydrolase activity
CVS41_05810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CVS41_05820	COG0840	transmembrane signaling receptor activity
CVS41_05830	COG2971	BadF BadG BcrA BcrD
CVS41_05840	COG4608	Belongs to the ABC transporter superfamily
CVS41_05845	COG0444	Belongs to the ABC transporter superfamily
CVS41_05850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVS41_05865	COG0784	Response regulator, receiver
CVS41_05865	COG2205	protein histidine kinase activity
CVS41_05895	COG3220	belongs to the UPF0276 family
CVS41_05925	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_05935	COG1289	transmembrane transporter activity
CVS41_05940	COG0303	'Molybdopterin
CVS41_05945	COG0746	molybdenum cofactor guanylyltransferase activity
CVS41_05955	COG4662	Binding-protein-dependent transport system inner membrane component
CVS41_05965	COG2204	response regulator
CVS41_05970	COG3852	Histidine kinase
CVS41_05980	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CVS41_06015	COG3383	formate dehydrogenase (NAD+) activity
CVS41_06015	COG3383	formate dehydrogenase (NAD+) activity
CVS41_06020	COG0437	4 iron, 4 sulfur cluster binding
CVS41_06040	COG0281	malic enzyme
CVS41_06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_06155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CVS41_06190	COG1857	crispr-associated protein
CVS41_06205	COG1518	maintenance of DNA repeat elements
CVS41_06210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CVS41_06250	COG0837	glucose binding
CVS41_06255	COG1737	Transcriptional regulator
CVS41_06260	COG0469	pyruvate kinase activity
CVS41_06280	COG1677	Flagellar hook-basal body complex protein FliE
CVS41_06290	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CVS41_06340	COG1987	bacterial-type flagellum assembly
CVS41_06345	COG1684	flagellar biosynthetic protein fliR
CVS41_06355	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CVS41_06365	COG0455	bacterial-type flagellum organization
CVS41_06380	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CVS41_06385	COG2198	Histidine kinase
CVS41_06385	COG0643	Histidine kinase
CVS41_06395	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CVS41_06400	COG1360	Flagellar Motor Protein
CVS41_06405	COG1192	Involved in chromosome partitioning
CVS41_06415	COG0835	chemotaxis
CVS41_06430	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVS41_06435	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVS41_06440	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CVS41_06445	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CVS41_06450	COG1138	Cytochrome C-type biogenesis protein
CVS41_06455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CVS41_06460	COG4235	cytochrome complex assembly
CVS41_06460	COG3088	subunit of a heme lyase
CVS41_06470	COG2853	Lipoprotein
CVS41_06480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CVS41_06485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CVS41_06495	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CVS41_06500	COG1882	Formate acetyltransferase
CVS41_06510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CVS41_06510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVS41_06540	COG0259	pyridoxamine-phosphate oxidase activity
CVS41_06565	COG2850	peptidyl-arginine hydroxylation
CVS41_06570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CVS41_06575	COG2915	High frequency lysogenization protein hflD homolog
CVS41_06580	COG0482	sulfurtransferase activity
CVS41_06590	COG1187	pseudouridine synthase activity
CVS41_06600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_06605	COG2271	Major facilitator Superfamily
CVS41_06610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_06610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_06610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_06635	COG0783	Belongs to the Dps family
CVS41_06665	COG1609	Transcriptional regulator
CVS41_06675	COG1263	PTS System
CVS41_06675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_06680	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CVS41_06685	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CVS41_06695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_06700	COG1960	acyl-CoA dehydrogenase activity
CVS41_06710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CVS41_06720	COG0210	DNA helicase
CVS41_06735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CVS41_06755	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CVS41_06805	COG1940	carbohydrate kinase activity
CVS41_06810	COG0457	Tetratricopeptide repeat
CVS41_06815	COG0477	Major facilitator Superfamily
CVS41_06815	COG2814	Major facilitator Superfamily
CVS41_06825	COG3383	formate dehydrogenase (NAD+) activity
CVS41_06835	COG0784	Response regulator, receiver
CVS41_06835	COG2205	protein histidine kinase activity
CVS41_06845	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CVS41_06850	COG2867	negative regulation of translational initiation
CVS41_06860	COG1473	amidohydrolase
CVS41_06865	COG1960	acyl-CoA dehydrogenase activity
CVS41_06870	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CVS41_06875	COG0121	glutamine amidotransferase
CVS41_06895	COG0784	Response regulator, receiver
CVS41_06895	COG2205	protein histidine kinase activity
CVS41_06905	COG2197	response regulator
CVS41_06910	COG3850	Histidine kinase
CVS41_06915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CVS41_06920	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_06930	COG0243	molybdopterin cofactor binding
CVS41_06935	COG0437	4 iron, 4 sulfur cluster binding
CVS41_06940	COG0348	domain, Protein
CVS41_06950	COG3005	denitrification pathway
CVS41_06955	COG0521	Mo-molybdopterin cofactor biosynthetic process
CVS41_06960	COG0315	cyclic pyranopterin monophosphate synthase activity
CVS41_06965	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CVS41_06970	COG0314	molybdopterin synthase activity
CVS41_06985	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CVS41_06990	COG2267	carboxylic ester hydrolase activity
CVS41_06995	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVS41_07005	COG0302	gtp cyclohydrolase
CVS41_07010	COG0840	transmembrane signaling receptor activity
CVS41_07015	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CVS41_07025	COG0583	DNA-binding transcription factor activity
CVS41_07030	COG2353	YceI-like domain
CVS41_07040	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CVS41_07055	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVS41_07065	COG1166	arginine decarboxylase activity
CVS41_07075	COG2015	COG2015, Alkyl sulfatase and related hydrolases
CVS41_07095	COG0814	amino acid
CVS41_07105	COG3681	Belongs to the UPF0597 family
CVS41_07110	COG2964	Protein conserved in bacteria
CVS41_07120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CVS41_07125	COG1288	antiporter activity
CVS41_07130	COG0436	Aminotransferase
CVS41_07140	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVS41_07145	COG1196	nuclear chromosome segregation
CVS41_07145	COG0741	lytic transglycosylase activity
CVS41_07145	COG0739	heme binding
CVS41_07170	COG0788	formyltetrahydrofolate deformylase activity
CVS41_07175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVS41_07185	COG3118	belongs to the thioredoxin family
CVS41_07195	COG0791	NLP P60 protein
CVS41_07200	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
CVS41_07210	COG0471	metal ion transport
CVS41_07220	COG1388	LysM domain
CVS41_07220	COG1376	ErfK ybiS ycfS ynhG family protein
CVS41_07230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_07235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_07240	COG0745	RESPONSE REGULATOR receiver
CVS41_07245	COG5002	protein histidine kinase activity
CVS41_07245	COG5000	phosphorelay sensor kinase activity
CVS41_07270	COG1388	LysM domain
CVS41_07270	COG0741	lytic transglycosylase activity
CVS41_07275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVS41_07280	COG2226	methyltransferase
CVS41_07285	COG0328	RNA-DNA hybrid ribonuclease activity
CVS41_07290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CVS41_07300	COG3437	response regulator, receiver
CVS41_07300	COG0784	Response regulator, receiver
CVS41_07305	COG2375	cellular response to nickel ion
CVS41_07310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_07315	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_07320	COG1120	ATPase activity
CVS41_07335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_07340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_07375	COG0708	Exodeoxyribonuclease III
CVS41_07405	COG3132	Protein of unknown function, DUF480
CVS41_07410	COG5001	Diguanylate cyclase
CVS41_07410	COG3300	MHYT domain
CVS41_07420	COG2841	Protein conserved in bacteria
CVS41_07430	COG0534	Mate efflux family protein
CVS41_07465	COG1309	transcriptional regulator
CVS41_07500	COG3152	Membrane
CVS41_07515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_07525	COG1482	cell wall glycoprotein biosynthetic process
CVS41_07530	COG2207	Transcriptional regulator
CVS41_07535	COG0538	isocitrate dehydrogenase activity
CVS41_07545	COG3048	D-serine ammonia-lyase activity
CVS41_07555	COG0583	DNA-binding transcription factor activity
CVS41_07565	COG0791	NLP P60 protein
CVS41_07570	COG0583	DNA-binding transcription factor activity
CVS41_07575	COG0450	alkyl hydroperoxide reductase
CVS41_07595	COG0500	methyltransferase
CVS41_07600	COG4106	trans-aconitate 2-methyltransferase activity
CVS41_07605	COG1801	Protein of unknown function DUF72
CVS41_07615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CVS41_07620	COG0217	transcriptional regulatory protein
CVS41_07625	COG1454	alcohol dehydrogenase
CVS41_07625	COG1012	belongs to the aldehyde dehydrogenase family
CVS41_07630	COG2095	MarC family integral membrane protein
CVS41_07640	COG0601	transmembrane transport
CVS41_07645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVS41_07650	COG0444	Belongs to the ABC transporter superfamily
CVS41_07660	COG0861	Integral membrane protein TerC family
CVS41_07665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CVS41_07695	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
CVS41_07700	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_07705	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CVS41_07710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVS41_07715	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CVS41_07720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CVS41_07735	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CVS41_07740	COG0505	Belongs to the CarA family
CVS41_07745	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CVS41_07755	COG0287	Prephenate dehydrogenase
CVS41_07755	COG1605	Chorismate mutase
CVS41_07760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_07770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_07775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_07810	COG0537	adenosine 5'-monophosphoramidase activity
CVS41_07825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CVS41_07840	COG1301	dicarboxylic acid transport
CVS41_07855	COG2354	Protein conserved in bacteria
CVS41_07865	COG2233	PERMEase
CVS41_07875	COG1252	NADH dehydrogenase
CVS41_07885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVS41_07895	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVS41_07905	COG2373	Large extracellular alpha-helical protein
CVS41_07910	COG4953	penicillin-binding protein 1C
CVS41_07925	COG0301	tRNA thio-modification
CVS41_07925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CVS41_07995	COG4310	Domain of unknown function (DUF2172)
CVS41_08010	COG2089	acid synthase
CVS41_08020	COG1083	cytidylyl-transferase
CVS41_08040	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_08055	COG1215	transferase activity, transferring glycosyl groups
CVS41_08065	COG0562	UDP-galactopyranose mutase
CVS41_08075	COG1216	Glycosyl transferase, family 2
CVS41_08095	COG2226	methyltransferase
CVS41_08100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CVS41_08105	COG1086	Polysaccharide biosynthesis protein
CVS41_08120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CVS41_08135	COG0346	lactoylglutathione lyase activity
CVS41_08140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CVS41_08150	COG4659	FMN binding
CVS41_08155	COG4658	electron transport chain
CVS41_08165	COG2878	Part of a membrane complex involved in electron transport
CVS41_08170	COG4657	Part of a membrane complex involved in electron transport
CVS41_08175	COG1403	HNH endonuclease
CVS41_08185	COG0346	lactoylglutathione lyase activity
CVS41_08195	COG1187	pseudouridine synthase activity
CVS41_08200	COG2807	transmembrane transport
CVS41_08205	COG0583	DNA-binding transcription factor activity
CVS41_08225	COG2979	Protein of unknown function (DUF533)
CVS41_08235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CVS41_08245	COG1294	oxidase, subunit
CVS41_08265	COG3220	belongs to the UPF0276 family
CVS41_08280	COG2249	NAD(P)H dehydrogenase (quinone) activity
CVS41_08285	COG2814	Major facilitator Superfamily
CVS41_08295	COG0656	L-ascorbic acid biosynthetic process
CVS41_08310	COG0583	DNA-binding transcription factor activity
CVS41_08320	COG0840	transmembrane signaling receptor activity
CVS41_08325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CVS41_08330	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CVS41_08335	COG2271	Major facilitator Superfamily
CVS41_08340	COG1349	DNA-binding transcription factor activity
CVS41_08350	COG0584	glycerophosphoryl diester phosphodiesterase
CVS41_08355	COG4574	serine-type endopeptidase inhibitor activity
CVS41_08360	COG3085	chromosome segregation
CVS41_08365	COG0583	DNA-binding transcription factor activity
CVS41_08375	COG1448	Aminotransferase
CVS41_08390	COG2333	competence protein COMEC
CVS41_08390	COG0658	competence protein
CVS41_08400	COG1663	tetraacyldisaccharide 4'-kinase activity
CVS41_08405	COG2835	tetraacyldisaccharide 4'-kinase activity
CVS41_08410	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CVS41_08415	COG2197	response regulator
CVS41_08420	COG0322	excinuclease ABC activity
CVS41_08445	COG0582	viral genome integration into host DNA
CVS41_08520	COG0367	asparagine synthase
CVS41_08530	COG4651	solute:proton antiporter activity
CVS41_08530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CVS41_08535	COG0647	UMP catabolic process
CVS41_08540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CVS41_08550	COG1902	pentaerythritol trinitrate reductase activity
CVS41_08555	COG1253	flavin adenine dinucleotide binding
CVS41_08565	COG0277	FAD linked oxidase domain protein
CVS41_08565	COG0247	lactate metabolic process
CVS41_08575	COG2050	protein possibly involved in aromatic compounds catabolism
CVS41_08585	COG2056	Na+-H+ antiporter family
CVS41_08590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CVS41_08595	COG0671	phosphoesterase, PA-phosphatase related
CVS41_08600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CVS41_08605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CVS41_08615	COG0101	tRNA pseudouridine synthase activity
CVS41_08620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CVS41_08625	COG0285	dihydrofolate synthase activity
CVS41_08630	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CVS41_08635	COG0393	Putative heavy-metal-binding
CVS41_08645	COG1648	precorrin-2 dehydrogenase activity
CVS41_08645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CVS41_08650	COG2221	Nitrite and sulphite reductase 4Fe-4S
CVS41_08665	COG4667	esterase of the alpha-beta hydrolase superfamily
CVS41_08670	COG1619	proteins homologs of microcin C7 resistance protein MccF
CVS41_08675	COG1368	sulfuric ester hydrolase activity
CVS41_08685	COG0527	aspartate kinase activity
CVS41_08690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CVS41_08690	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CVS41_08695	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CVS41_08715	COG0596	Alpha beta hydrolase
CVS41_08735	COG1136	(ABC) transporter
CVS41_08750	COG2814	Major facilitator Superfamily
CVS41_08775	COG0672	)-iron permease
CVS41_08810	COG0659	secondary active sulfate transmembrane transporter activity
CVS41_08825	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CVS41_08825	COG0392	lysyltransferase activity
CVS41_08835	COG2205	protein histidine kinase activity
CVS41_08840	COG0745	RESPONSE REGULATOR receiver
CVS41_08860	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CVS41_08865	COG1278	Cold shock
CVS41_08870	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CVS41_08875	COG0542	response to heat
CVS41_08880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CVS41_08885	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CVS41_08890	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CVS41_08895	COG3134	Outer membrane lipoprotein
CVS41_08900	COG3706	GGDEF domain
CVS41_08905	COG0492	ferredoxin-NADP+ reductase activity
CVS41_08910	COG0686	Belongs to the AlaDH PNT family
CVS41_08920	COG0531	amino acid
CVS41_08920	COG1674	ftsk spoiiie
CVS41_08925	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CVS41_08930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CVS41_08935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CVS41_08940	COG1286	toxin biosynthetic process
CVS41_08945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CVS41_08955	COG0563	adenylate kinase activity
CVS41_08960	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CVS41_08970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVS41_08985	COG5001	Diguanylate cyclase
CVS41_08985	COG3300	MHYT domain
CVS41_09015	COG0598	Magnesium transport protein CorA
CVS41_09035	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CVS41_09040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CVS41_09045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_09060	COG0513	Belongs to the DEAD box helicase family
CVS41_09065	COG0386	Belongs to the glutathione peroxidase family
CVS41_09075	COG1181	Belongs to the D-alanine--D-alanine ligase family
CVS41_09080	COG0383	alpha-mannosidase activity
CVS41_09085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_09085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_09085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_09090	COG2188	Transcriptional regulator
CVS41_09095	COG1570	exodeoxyribonuclease VII activity
CVS41_09100	COG1874	Beta-galactosidase
CVS41_09100	COG0366	Alpha amylase catalytic
CVS41_09115	COG0517	IMP dehydrogenase activity
CVS41_09115	COG0516	GMP reductase activity
CVS41_09120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CVS41_09120	COG0519	Catalyzes the synthesis of GMP from XMP
CVS41_09160	COG1025	Belongs to the peptidase M16 family
CVS41_09165	COG2062	phosphohistidine phosphatase, SixA
CVS41_09175	COG0697	spore germination
CVS41_09180	COG4166	transmembrane transport
CVS41_09185	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CVS41_09190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CVS41_09200	COG4591	ABC-type transport system involved in lipoprotein release permease component
CVS41_09205	COG1136	(ABC) transporter
CVS41_09210	COG4591	ABC-type transport system involved in lipoprotein release permease component
CVS41_09215	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CVS41_09230	COG0544	peptidyl-prolyl cis-trans isomerase activity
CVS41_09235	COG0740	serine-type endopeptidase activity
CVS41_09240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CVS41_09245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CVS41_09250	COG0776	regulation of translation
CVS41_09255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVS41_09260	COG0488	(ABC) transporter
CVS41_09265	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CVS41_09270	COG3162	membrane
CVS41_09285	COG1024	Enoyl-CoA hydratase
CVS41_09290	COG1115	amino acid carrier protein
CVS41_09305	COG2801	Transposase and inactivated derivatives
CVS41_09320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_09330	COG3842	ATPase activity
CVS41_09335	COG1840	ABC-type Fe3 transport system, periplasmic component
CVS41_09345	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CVS41_09355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_09370	COG4235	cytochrome complex assembly
CVS41_09370	COG3088	subunit of a heme lyase
CVS41_09380	COG1138	Cytochrome C-type biogenesis protein
CVS41_09385	COG3301	Polysulphide reductase, NrfD
CVS41_09390	COG0437	4 iron, 4 sulfur cluster binding
CVS41_09395	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CVS41_09410	COG0247	lactate metabolic process
CVS41_09415	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
CVS41_09420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CVS41_09425	COG3012	SEC-C Motif Domain Protein
CVS41_09430	COG0840	transmembrane signaling receptor activity
CVS41_09435	COG1846	Transcriptional regulator
CVS41_09435	COG1940	carbohydrate kinase activity
CVS41_09445	COG0730	response to heat
CVS41_09450	COG0583	DNA-binding transcription factor activity
CVS41_09465	COG3593	DNA synthesis involved in DNA repair
CVS41_09500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CVS41_09505	COG1011	Hydrolase
CVS41_09520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CVS41_09525	COG2832	Protein of unknown function (DUF454)
CVS41_09530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CVS41_09540	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CVS41_09550	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CVS41_09565	COG1560	Kdo2-lipid A biosynthetic process
CVS41_09570	COG1560	Kdo2-lipid A biosynthetic process
CVS41_09595	COG0417	DNA replication proofreading
CVS41_09610	COG1451	nucleotide metabolic process
CVS41_09625	COG3069	C4-dicarboxylate transmembrane transporter activity
CVS41_09640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_09640	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CVS41_09645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CVS41_09655	COG0569	domain protein
CVS41_09655	COG2985	domain, Protein
CVS41_09670	COG0556	nucleotide-excision repair
CVS41_09680	COG0586	Pfam SNARE associated Golgi protein
CVS41_09685	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CVS41_09690	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVS41_09705	COG4681	YaeQ
CVS41_09750	COG0534	Mate efflux family protein
CVS41_09765	COG0307	riboflavin synthase, alpha
CVS41_09775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CVS41_09780	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CVS41_09785	COG0697	spore germination
CVS41_09790	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CVS41_09830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CVS41_09840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CVS41_09845	COG2894	cell division
CVS41_09850	COG0850	regulation of cytokinetic process
CVS41_09855	COG3100	YcgL domain-containing protein
CVS41_09860	COG1760	l-serine dehydratase
CVS41_09870	COG1760	l-serine dehydratase
CVS41_09875	COG3123	guanosine phosphorylase activity
CVS41_09885	COG0205	6-phosphofructokinase activity
CVS41_09895	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CVS41_09900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVS41_09910	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CVS41_09915	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CVS41_09935	COG0242	peptide deformylase activity
CVS41_09970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CVS41_09975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CVS41_09980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVS41_09990	COG0549	Belongs to the carbamate kinase family
CVS41_10005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CVS41_10015	COG0697	spore germination
CVS41_10025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CVS41_10025	COG3608	succinylglutamate desuccinylase aspartoacylase
CVS41_10030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CVS41_10035	COG2068	MobA-Related Protein
CVS41_10040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_10040	COG0493	'glutamate synthase
CVS41_10045	COG0402	S-adenosylhomocysteine deaminase activity
CVS41_10050	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CVS41_10055	COG2080	2 iron, 2 sulfur cluster binding
CVS41_10055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVS41_10060	COG2233	PERMEase
CVS41_10065	COG0402	S-adenosylhomocysteine deaminase activity
CVS41_10070	COG2252	PERMEase
CVS41_10075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CVS41_10080	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CVS41_10085	COG2080	2 iron, 2 sulfur cluster binding
CVS41_10090	COG3134	Outer membrane lipoprotein
CVS41_10105	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_10110	COG3706	GGDEF domain
CVS41_10125	COG0107	imidazoleglycerol-phosphate synthase activity
CVS41_10130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CVS41_10135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CVS41_10140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CVS41_10140	COG0131	Imidazoleglycerol-phosphate dehydratase
CVS41_10145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CVS41_10150	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CVS41_10155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CVS41_10165	COG1199	ATP-dependent helicase activity
CVS41_10170	COG1214	PFAM Peptidase M22, glycoprotease
CVS41_10180	COG2267	carboxylic ester hydrolase activity
CVS41_10185	COG0318	PFAM AMP-dependent synthetase and ligase
CVS41_10195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CVS41_10200	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CVS41_10205	COG0709	Synthesizes selenophosphate from selenide and ATP
CVS41_10220	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CVS41_10225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CVS41_10235	COG0840	transmembrane signaling receptor activity
CVS41_10240	COG1254	Belongs to the acylphosphatase family
CVS41_10250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_10250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_10255	COG0489	protein tyrosine kinase activity
CVS41_10260	COG0572	uridine kinase
CVS41_10265	COG0717	Belongs to the dCTP deaminase family
CVS41_10270	COG0306	phosphate transporter
CVS41_10275	COG3313	Fe-S protein
CVS41_10280	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CVS41_10285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_10290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVS41_10295	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CVS41_10305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CVS41_10315	COG0366	Alpha amylase catalytic
CVS41_10330	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CVS41_10335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CVS41_10340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CVS41_10345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CVS41_10350	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CVS41_10355	COG0072	phenylalanine-tRNA ligase activity
CVS41_10355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_10360	COG0776	regulation of translation
CVS41_10365	COG2205	protein histidine kinase activity
CVS41_10365	COG0784	Response regulator, receiver
CVS41_10380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CVS41_10390	COG5001	Diguanylate cyclase
CVS41_10390	COG3300	MHYT domain
CVS41_10395	COG1609	Transcriptional regulator
CVS41_10400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CVS41_10405	COG1879	ABC-type sugar transport system periplasmic component
CVS41_10410	COG1172	Belongs to the binding-protein-dependent transport system permease family
CVS41_10415	COG1129	ABC transporter
CVS41_10420	COG1869	D-ribose catabolic process
CVS41_10425	COG0625	glutathione transferase activity
CVS41_10435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CVS41_10440	COG1177	transmembrane transport
CVS41_10445	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVS41_10465	COG0037	tRNA processing
CVS41_10470	COG0589	response to stress
CVS41_10475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CVS41_10490	COG2217	Heavy metal translocating P-type atpase
CVS41_10500	COG2010	Cytochrome c
CVS41_10515	COG3278	Belongs to the heme-copper respiratory oxidase family
CVS41_10525	COG1956	GAF domain-containing protein
CVS41_10530	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CVS41_10540	COG0308	aminopeptidase N
CVS41_10550	COG2902	Dehydrogenase
CVS41_10555	COG0167	dihydroorotate dehydrogenase activity
CVS41_10570	COG0254	rRNA binding
CVS41_10575	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CVS41_10580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CVS41_10580	COG0116	Belongs to the methyltransferase superfamily
CVS41_10600	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CVS41_10605	COG1067	ATP-dependent peptidase activity
CVS41_10630	COG3141	response to X-ray
CVS41_10635	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CVS41_10640	COG4221	oxidoreductase activity
CVS41_10685	COG0372	Belongs to the citrate synthase family
CVS41_10690	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CVS41_10700	COG2995	paraquat-inducible protein a
CVS41_10705	COG3008	intermembrane lipid transfer
CVS41_10710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CVS41_10710	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CVS41_10725	COG0084	hydrolase, TatD family'
CVS41_10730	COG0470	DNA polymerase III
CVS41_10735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CVS41_10740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CVS41_10745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CVS41_10750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CVS41_10755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CVS41_10760	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_10770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CVS41_10775	COG0416	fatty acid biosynthetic process
CVS41_10780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CVS41_10785	COG1399	metal-binding, possibly nucleic acid-binding protein
CVS41_10790	COG0424	maF-like protein
CVS41_10805	COG1530	ribonuclease E activity
CVS41_10810	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CVS41_10810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_10810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CVS41_10815	COG1105	Belongs to the carbohydrate kinase PfkB family
CVS41_10820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_10820	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_10825	COG1609	Transcriptional regulator
CVS41_10830	COG0814	amino acid
CVS41_10860	COG0513	Belongs to the DEAD box helicase family
CVS41_10870	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CVS41_10875	COG2890	protein-(glutamine-N5) methyltransferase activity
CVS41_10880	COG2840	Smr protein MutS2
CVS41_10885	COG3706	GGDEF domain
CVS41_10890	COG0406	alpha-ribazole phosphatase activity
CVS41_10910	COG2824	Alkylphosphonate utilization operon protein PhnA
CVS41_10980	COG0494	nUDIX hydrolase
CVS41_10985	COG0814	amino acid
CVS41_10995	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CVS41_11000	COG0514	ATP-dependent DNA helicase (RecQ)
CVS41_11005	COG2766	serine protein kinase
CVS41_11010	COG2718	Belongs to the UPF0229 family
CVS41_11015	COG2719	SpoVR family
CVS41_11020	COG1024	Enoyl-CoA hydratase
CVS41_11020	COG1250	3-hydroxyacyl-CoA dehydrogenase
CVS41_11025	COG0183	Belongs to the thiolase family
CVS41_11030	COG0714	Associated with various cellular activities
CVS41_11050	COG2304	oxidoreductase activity
CVS41_11060	COG1595	DNA-templated transcription, initiation
CVS41_11070	COG2067	long-chain fatty acid transport protein
CVS41_11075	COG2067	long-chain fatty acid transport protein
CVS41_11080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CVS41_11095	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CVS41_11105	COG1643	Atp-dependent helicase
CVS41_11115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_11120	COG3119	arylsulfatase activity
CVS41_11125	COG0714	Associated with various cellular activities
CVS41_11140	COG2304	oxidoreductase activity
CVS41_11145	COG2304	oxidoreductase activity
CVS41_11170	COG0641	radical SAM
CVS41_11185	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_11230	COG2925	Exonuclease
CVS41_11240	COG3345	alpha-galactosidase
CVS41_11245	COG1380	Effector of murein hydrolase LrgA
CVS41_11250	COG1346	cytolysis
CVS41_11255	COG0295	cytidine deaminase activity
CVS41_11260	COG3033	Beta-eliminating lyase
CVS41_11270	COG3046	protein related to deoxyribodipyrimidine photolyase
CVS41_11275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_11280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CVS41_11305	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_11325	COG0454	-acetyltransferase
CVS41_11335	COG3158	transport of potassium into the cell
CVS41_11340	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CVS41_11345	COG0651	ATP synthesis coupled electron transport
CVS41_11350	COG0650	Formate hydrogenlyase subunit 4
CVS41_11355	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
CVS41_11355	COG3261	NADH dehydrogenase
CVS41_11360	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_11365	COG3260	NADH ubiquinone oxidoreductase 20
CVS41_11375	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CVS41_11380	COG1921	L-seryl-tRNASec selenium transferase activity
CVS41_11390	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CVS41_11395	COG0298	carbon dioxide binding
CVS41_11405	COG0309	Hydrogenase expression formation protein (HypE)
CVS41_11410	COG0375	protein maturation
CVS41_11415	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CVS41_11420	COG1124	(ABC) transporter
CVS41_11430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CVS41_11435	COG0601	transmembrane transport
CVS41_11445	COG1773	rubredoxin
CVS41_11450	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CVS41_11455	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CVS41_11460	COG5557	Pfam Polysulphide reductase, NrfD
CVS41_11465	COG0437	4 iron, 4 sulfur cluster binding
CVS41_11470	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
CVS41_11475	COG2203	Gaf domain
CVS41_11475	COG4251	negative regulation of phosphorylation
CVS41_11475	COG3706	GGDEF domain
CVS41_11475	COG5001	Diguanylate cyclase
CVS41_11480	COG0438	transferase activity, transferring glycosyl groups
CVS41_11485	COG0438	transferase activity, transferring glycosyl groups
CVS41_11505	COG0438	transferase activity, transferring glycosyl groups
CVS41_11550	COG0438	transferase activity, transferring glycosyl groups
CVS41_11555	COG1215	transferase activity, transferring glycosyl groups
CVS41_11560	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CVS41_11600	COG2205	protein histidine kinase activity
CVS41_11600	COG0784	Response regulator, receiver
CVS41_11615	COG0730	response to heat
CVS41_11625	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_11635	COG1024	Enoyl-CoA hydratase
CVS41_11640	COG1024	Enoyl-CoA hydratase
CVS41_11645	COG1960	acyl-CoA dehydrogenase activity
CVS41_11650	COG1960	acyl-CoA dehydrogenase activity
CVS41_11655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CVS41_11660	COG1024	Enoyl-CoA hydratase
CVS41_11690	COG1584	GPR1 FUN34 yaaH family protein
CVS41_11705	COG0045	succinate-CoA ligase (ADP-forming) activity
CVS41_11710	COG0508	dehydrogenase complex catalyzes the overall conversion of
CVS41_11715	COG0567	Dehydrogenase, E1 component
CVS41_11725	COG1053	succinate dehydrogenase
CVS41_11730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CVS41_11735	COG2009	succinate dehydrogenase
CVS41_11770	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CVS41_11785	COG2501	S4 domain
CVS41_11795	COG1132	(ABC) transporter
CVS41_11800	COG1132	(ABC) transporter
CVS41_11810	COG3118	belongs to the thioredoxin family
CVS41_11815	COG0471	metal ion transport
CVS41_11820	COG0058	SHG alpha-glucan phosphorylase activity
CVS41_11845	COG1882	Formate acetyltransferase
CVS41_11850	COG2116	formate transmembrane transporter activity
CVS41_11855	COG1944	ATP diphosphatase activity
CVS41_11860	COG2723	6-phospho-beta-galactosidase activity
CVS41_11865	COG0583	DNA-binding transcription factor activity
CVS41_11875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CVS41_11880	COG0583	DNA-binding transcription factor activity
CVS41_11890	COG1335	isochorismatase
CVS41_11900	COG2271	Major facilitator Superfamily
CVS41_11905	COG0583	DNA-binding transcription factor activity
CVS41_11910	COG0583	DNA-binding transcription factor activity
CVS41_11915	COG2910	NAD(P)H-binding
CVS41_11945	COG0861	Integral membrane protein TerC family
CVS41_11950	COG2885	chlorophyll binding
CVS41_11955	COG2199	diguanylate cyclase activity
CVS41_11970	COG2154	pterin-4-alpha-carbinolamine dehydratase
CVS41_11980	COG1012	belongs to the aldehyde dehydrogenase family
CVS41_11985	COG1177	transmembrane transport
CVS41_11990	COG1176	ABC-type spermidine putrescine transport system, permease component I
CVS41_11995	COG3842	ATPase activity
CVS41_12000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CVS41_12005	COG0583	DNA-binding transcription factor activity
CVS41_12010	COG3768	UPF0283 membrane protein
CVS41_12015	COG3106	COG3106 Predicted ATPase
CVS41_12030	COG1842	Phage shock protein A
CVS41_12035	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CVS41_12045	COG4168	peptide transport system, permease
CVS41_12050	COG4171	peptide transport system, permease
CVS41_12055	COG4172	Belongs to the ABC transporter superfamily
CVS41_12060	COG4172	Belongs to the ABC transporter superfamily
CVS41_12065	COG0326	Molecular chaperone. Has ATPase activity
CVS41_12070	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CVS41_12090	COG1435	thymidine kinase activity
CVS41_12095	COG1757	Na H antiporter
CVS41_12100	COG2916	Histone family protein nucleoid-structuring protein H-NS
CVS41_12105	COG2096	Adenosyltransferase
CVS41_12110	COG3530	Putative quorum-sensing-regulated virulence factor
CVS41_12115	COG0602	queuosine metabolic process
CVS41_12120	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CVS41_12140	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CVS41_12150	COG0776	regulation of translation
CVS41_12155	COG0539	negative regulation of cytoplasmic translation
CVS41_12160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CVS41_12165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CVS41_12170	COG0583	DNA-binding transcription factor activity
CVS41_12180	COG2814	Major facilitator Superfamily
CVS41_12200	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CVS41_12205	COG5001	Diguanylate cyclase
CVS41_12205	COG3300	MHYT domain
CVS41_12210	COG0583	DNA-binding transcription factor activity
CVS41_12215	COG3437	response regulator, receiver
CVS41_12240	COG4989	oxidoreductase activity
CVS41_12245	COG0724	RNA recognition motif
CVS41_12255	COG1126	abc transporter atp-binding protein
CVS41_12260	COG0765	amino acid transport
CVS41_12270	COG4597	amino acid ABC transporter
CVS41_12275	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CVS41_12285	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CVS41_12300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CVS41_12305	COG1360	Flagellar Motor Protein
CVS41_12310	COG4771	TonB-dependent receptor
CVS41_12315	COG1770	oligopeptidase
CVS41_12335	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_12340	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_12345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_12345	COG0649	NAD binding
CVS41_12360	COG1034	ATP synthesis coupled electron transport
CVS41_12365	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CVS41_12370	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_12375	COG0839	Belongs to the complex I subunit 6 family
CVS41_12380	COG0713	ATP synthesis coupled electron transport
CVS41_12390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CVS41_12395	COG1007	ATP synthesis coupled electron transport
CVS41_12410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_12410	COG2199	diguanylate cyclase activity
CVS41_12415	COG0047	phosphoribosylformylglycinamidine synthase activity
CVS41_12415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CVS41_12420	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CVS41_12430	COG1645	bacterial-type flagellum-dependent swarming motility
CVS41_12435	COG1160	GTP binding
CVS41_12440	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_12445	COG2976	Protein conserved in bacteria
CVS41_12450	COG0124	histidyl-tRNA synthetase
CVS41_12470	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CVS41_12475	COG0105	UTP biosynthetic process
CVS41_12490	COG0633	Ferredoxin
CVS41_12495	COG0443	Heat shock 70 kDa protein
CVS41_12500	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CVS41_12510	COG0822	iron-sulfur transferase activity
CVS41_12515	COG1104	cysteine desulfurase activity
CVS41_12560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_12565	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CVS41_12570	COG1862	Preprotein translocase
CVS41_12575	COG0343	queuine tRNA-ribosyltransferase activity
CVS41_12580	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CVS41_12585	COG0517	IMP dehydrogenase activity
CVS41_12590	COG0450	alkyl hydroperoxide reductase
CVS41_12595	COG3634	alkyl hydroperoxide reductase activity
CVS41_12645	COG1242	4 iron, 4 sulfur cluster binding
CVS41_12650	COG0069	glutamate synthase activity
CVS41_12650	COG0067	glutamate synthase
CVS41_12650	COG0070	glutamate synthase
CVS41_12655	COG0493	'glutamate synthase
CVS41_12670	COG0513	Belongs to the DEAD box helicase family
CVS41_12695	COG0023	Translation Initiation Factor
CVS41_12700	COG2119	membrane
CVS41_12745	COG0215	cysteine-tRNA ligase activity
CVS41_12750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVS41_12760	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_12770	COG2261	transglycosylase associated protein
CVS41_12775	COG0642	Histidine kinase
CVS41_12800	COG0625	glutathione transferase activity
CVS41_12810	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CVS41_12825	COG0564	pseudouridine synthase activity
CVS41_12830	COG4160	amino acid transport
CVS41_12835	COG4215	(ABC) transporter
CVS41_12840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_12850	COG2431	L-lysine efflux transmembrane transporter activity
CVS41_12855	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CVS41_12860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_12865	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
CVS41_12875	COG1393	Belongs to the ArsC family
CVS41_12885	COG4783	chaperone-mediated protein folding
CVS41_12915	COG3842	ATPase activity
CVS41_12925	COG1175	transmembrane transport
CVS41_12935	COG3081	Nucleoid-associated protein
CVS41_12940	COG3082	Protein of unknown function (DUF1414)
CVS41_12945	COG3083	sulfuric ester hydrolase activity
CVS41_12950	COG1464	Belongs to the NlpA lipoprotein family
CVS41_12965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CVS41_12965	COG0574	Belongs to the PEP-utilizing enzyme family
CVS41_12970	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CVS41_12995	COG0840	transmembrane signaling receptor activity
CVS41_13000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVS41_13000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CVS41_13005	COG0509	glycine decarboxylation via glycine cleavage system
CVS41_13010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CVS41_13015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVS41_13020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CVS41_13030	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CVS41_13040	COG2814	Major facilitator Superfamily
CVS41_13045	COG0625	glutathione transferase activity
CVS41_13055	COG0483	inositol monophosphate 1-phosphatase activity
CVS41_13100	COG1199	ATP-dependent helicase activity
CVS41_13110	COG0123	including yeast histone deacetylase and acetoin utilization protein
CVS41_13115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CVS41_13120	COG1785	Belongs to the alkaline phosphatase family
CVS41_13140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVS41_13145	COG2197	response regulator
CVS41_13155	COG2271	Major facilitator Superfamily
CVS41_13160	COG3706	GGDEF domain
CVS41_13165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_13170	COG0765	amino acid transport
CVS41_13175	COG1126	abc transporter atp-binding protein
CVS41_13190	COG0531	amino acid
CVS41_13205	COG1253	flavin adenine dinucleotide binding
CVS41_13210	COG0704	Plays a role in the regulation of phosphate uptake
CVS41_13220	COG0581	inorganic phosphate transmembrane transporter activity
CVS41_13225	COG0573	inorganic phosphate transmembrane transporter activity
CVS41_13230	COG0590	tRNA wobble adenosine to inosine editing
CVS41_13240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CVS41_13260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CVS41_13265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CVS41_13270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CVS41_13275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CVS41_13280	COG2204	response regulator
CVS41_13285	COG3852	Histidine kinase
CVS41_13290	COG2204	response regulator
CVS41_13300	COG2716	regulation of RNA biosynthetic process
CVS41_13305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CVS41_13310	COG0248	Ppx GppA phosphatase
CVS41_13315	COG2239	Acts as a magnesium transporter
CVS41_13320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CVS41_13335	COG1706	bacterial-type flagellum-dependent cell motility
CVS41_13340	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CVS41_13345	COG4786	Flagellar basal body rod
CVS41_13350	COG4787	bacterial-type flagellum-dependent cell motility
CVS41_13360	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CVS41_13365	COG1558	bacterial-type flagellum-dependent cell motility
CVS41_13370	COG1815	bacterial-type flagellum-dependent cell motility
CVS41_13375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CVS41_13380	COG0784	Response regulator, receiver
CVS41_13380	COG0835	chemotaxis
CVS41_13385	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CVS41_13400	COG0622	Phosphoesterase
CVS41_13405	COG4166	transmembrane transport
CVS41_13415	COG1187	pseudouridine synthase activity
CVS41_13420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_13430	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVS41_13435	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVS41_13445	COG1349	DNA-binding transcription factor activity
CVS41_13450	COG4166	transmembrane transport
CVS41_13475	COG1278	Cold shock
CVS41_13500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CVS41_13500	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CVS41_13505	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_13510	COG1535	isochorismatase
CVS41_13510	COG3433	isochorismatase activity
CVS41_13515	COG1021	2,3-dihydroxybenzoate-AMP ligase
CVS41_13520	COG1169	isochorismate synthase
CVS41_13525	COG4771	TonB-dependent receptor
CVS41_13530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CVS41_13540	COG0741	lytic transglycosylase activity
CVS41_13550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CVS41_13570	COG2911	Protein conserved in bacteria
CVS41_13575	COG0729	surface antigen
CVS41_13585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVS41_13595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CVS41_13605	COG4134	Bacterial extracellular solute-binding protein
CVS41_13615	COG4136	ATPase activity
CVS41_13620	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CVS41_13625	COG2951	lytic endotransglycosylase activity
CVS41_13630	COG1846	Transcriptional regulator
CVS41_13640	COG0033	Phosphoglucomutase
CVS41_13645	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
CVS41_13650	COG0596	Alpha beta hydrolase
CVS41_13665	COG0716	FMN binding
CVS41_13675	COG0735	belongs to the Fur family
CVS41_13680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_13690	COG1263	PTS System
CVS41_13690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_13690	COG2190	(PTS) system
CVS41_13695	COG0363	glucosamine-6-phosphate deaminase activity
CVS41_13700	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CVS41_13705	COG1846	Transcriptional regulator
CVS41_13705	COG1940	carbohydrate kinase activity
CVS41_13715	COG2199	diguanylate cyclase activity
CVS41_13715	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CVS41_13720	COG3275	phosphorelay sensor kinase activity
CVS41_13725	COG3279	Response regulator of the LytR AlgR family
CVS41_13730	COG1966	Carbon starvation protein
CVS41_13740	COG1566	PFAM secretion protein HlyD family protein
CVS41_13745	COG1061	Type III restriction enzyme res subunit
CVS41_13750	COG2027	D-alanyl-D-alanine carboxypeptidase
CVS41_13755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CVS41_13760	COG3021	interspecies interaction between organisms
CVS41_13770	COG1607	acyl-coa hydrolase
CVS41_13775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CVS41_13780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CVS41_13780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CVS41_13780	COG0674	pyruvate-flavodoxin oxidoreductase activity
CVS41_13780	COG1013	pyruvate-flavodoxin oxidoreductase activity
CVS41_13795	COG3217	Mosc domain protein beta barrel domain protein
CVS41_13795	COG0633	Ferredoxin
CVS41_13795	COG3217	Mosc domain protein beta barrel domain protein
CVS41_13795	COG0633	Ferredoxin
CVS41_13805	COG0501	Belongs to the peptidase M48B family
CVS41_13810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CVS41_13815	COG1073	alpha beta
CVS41_13815	COG2226	methyltransferase
CVS41_13820	COG0156	8-amino-7-oxononanoate synthase activity
CVS41_13825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CVS41_13830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CVS41_13845	COG0017	Asparaginyl-tRNA synthetase
CVS41_13855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CVS41_13865	COG1473	amidohydrolase
CVS41_13870	COG3069	C4-dicarboxylate transmembrane transporter activity
CVS41_13880	COG1393	Belongs to the ArsC family
CVS41_13885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CVS41_13890	COG1876	peptidase activity
CVS41_13900	COG3263	regulation of cellular component size
CVS41_13915	COG1280	lysine exporter protein (LysE YggA)
CVS41_13950	COG0564	pseudouridine synthase activity
CVS41_13960	COG1454	alcohol dehydrogenase
CVS41_13965	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_13970	COG0702	epimerase
CVS41_13980	COG0095	Lipoate-protein ligase
CVS41_13990	COG0577	efflux transmembrane transporter activity
CVS41_13990	COG1136	(ABC) transporter
CVS41_13995	COG1136	(ABC) transporter
CVS41_13995	COG0577	efflux transmembrane transporter activity
CVS41_14000	COG0577	efflux transmembrane transporter activity
CVS41_14000	COG1136	(ABC) transporter
CVS41_14005	COG1566	PFAM secretion protein HlyD family protein
CVS41_14020	COG2391	methyltransferase activity
CVS41_14040	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVS41_14050	COG1285	pathogenesis
CVS41_14080	COG0484	heat shock protein binding
CVS41_14085	COG0443	Heat shock 70 kDa protein
CVS41_14090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CVS41_14095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CVS41_14100	COG0497	DNA recombination
CVS41_14110	COG1227	inorganic diphosphatase activity
CVS41_14115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_14120	COG0577	efflux transmembrane transporter activity
CVS41_14120	COG1136	(ABC) transporter
CVS41_14125	COG1538	Outer membrane efflux protein
CVS41_14140	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_14160	COG0489	protein tyrosine kinase activity
CVS41_14160	COG3206	protein involved in exopolysaccharide biosynthesis
CVS41_14165	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CVS41_14170	COG1596	polysaccharide export
CVS41_14200	COG0438	transferase activity, transferring glycosyl groups
CVS41_14200	COG0297	glycogen (starch) synthase activity
CVS41_14205	COG0438	transferase activity, transferring glycosyl groups
CVS41_14225	COG2244	polysaccharide biosynthetic process
CVS41_14240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CVS41_14260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CVS41_14295	COG1091	dTDP-4-dehydrorhamnose reductase activity
CVS41_14305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CVS41_14310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_14315	COG1309	transcriptional regulator
CVS41_14330	COG1342	Belongs to the UPF0251 family
CVS41_14350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CVS41_14370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CVS41_14375	COG0083	homoserine kinase activity
CVS41_14385	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CVS41_14390	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CVS41_14395	COG1946	Acyl-CoA thioesterase
CVS41_14405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CVS41_14415	COG0009	L-threonylcarbamoyladenylate synthase
CVS41_14425	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CVS41_14430	COG0512	Glutamine amidotransferase of anthranilate synthase
CVS41_14430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CVS41_14435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CVS41_14440	COG0135	phosphoribosylanthranilate isomerase activity
CVS41_14440	COG0134	indole-3-glycerol-phosphate synthase activity
CVS41_14445	COG0133	tryptophan synthase activity
CVS41_14450	COG0159	tryptophan synthase activity
CVS41_14465	COG1988	membrane-bound metal-dependent
CVS41_14485	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_14495	COG0798	PFAM Bile acid sodium symporter
CVS41_14510	COG0640	Transcriptional regulator
CVS41_14525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CVS41_14535	COG0745	RESPONSE REGULATOR receiver
CVS41_14550	COG4988	ABC transporter
CVS41_14555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CVS41_14575	COG1720	tRNA m6t6A37 methyltransferase activity
CVS41_14580	COG3038	cytochrome b561
CVS41_14590	COG0745	RESPONSE REGULATOR receiver
CVS41_14600	COG2862	Uncharacterized protein family, UPF0114
CVS41_14615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CVS41_14620	COG1917	Cupin 2, conserved barrel domain protein
CVS41_14620	COG1396	sequence-specific DNA binding
CVS41_14635	COG0531	amino acid
CVS41_14645	COG0531	amino acid
CVS41_14650	COG1283	sodium-dependent phosphate transmembrane transporter activity
CVS41_14660	COG0405	Gamma-glutamyltransferase
CVS41_14665	COG2974	May be involved in recombination
CVS41_14675	COG0420	3'-5' exonuclease activity
CVS41_14680	COG0419	ATPase involved in DNA repair
CVS41_14695	COG0469	pyruvate kinase activity
CVS41_14700	COG3264	Mechanosensitive ion channel
CVS41_14700	COG1196	nuclear chromosome segregation
CVS41_14710	COG3590	peptidase
CVS41_14715	COG3706	GGDEF domain
CVS41_14720	COG2190	(PTS) system
CVS41_14730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CVS41_14735	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CVS41_14740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_14755	COG3437	response regulator, receiver
CVS41_14755	COG2770	Histidine kinase
CVS41_14760	COG3267	Type II secretory pathway component ExeA
CVS41_14760	COG3409	Peptidoglycan-binding domain 1 protein
CVS41_14770	COG3031	protein transport across the cell outer membrane
CVS41_14780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVS41_14785	COG1459	type II secretion system
CVS41_14790	COG2165	general secretion pathway protein
CVS41_14800	COG2165	general secretion pathway protein
CVS41_14805	COG4795	General secretion pathway protein
CVS41_14810	COG3156	type II secretion system protein K
CVS41_14820	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CVS41_14835	COG0670	Belongs to the BI1 family
CVS41_14840	COG1289	transmembrane transporter activity
CVS41_14845	COG2920	part of a sulfur-relay system
CVS41_14850	COG0673	inositol 2-dehydrogenase activity
CVS41_14855	COG0583	DNA-binding transcription factor activity
CVS41_14895	COG1032	radical SAM domain protein
CVS41_14905	COG1566	PFAM secretion protein HlyD family protein
CVS41_14910	COG3706	GGDEF domain
CVS41_14915	COG1752	Esterase of the alpha-beta hydrolase superfamily
CVS41_14920	COG0531	amino acid
CVS41_14955	COG0281	malic enzyme
CVS41_14965	COG0534	Mate efflux family protein
CVS41_14975	COG3706	GGDEF domain
CVS41_14980	COG2233	PERMEase
CVS41_14985	COG0095	Lipoate-protein ligase
CVS41_14990	COG1115	amino acid carrier protein
CVS41_14995	COG0019	diaminopimelate decarboxylase activity
CVS41_15015	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CVS41_15030	COG0545	Peptidyl-prolyl cis-trans isomerase
CVS41_15035	COG3142	Participates in the control of copper homeostasis
CVS41_15050	COG4783	chaperone-mediated protein folding
CVS41_15060	COG5002	protein histidine kinase activity
CVS41_15065	COG0745	RESPONSE REGULATOR receiver
CVS41_15070	COG0346	lactoylglutathione lyase activity
CVS41_15085	COG0697	spore germination
CVS41_15095	COG3290	protein histidine kinase activity
CVS41_15100	COG0281	malic enzyme
CVS41_15115	COG1846	Transcriptional regulator
CVS41_15120	COG1566	PFAM secretion protein HlyD family protein
CVS41_15150	COG0602	queuosine metabolic process
CVS41_15155	COG1328	CTP reductase activity
CVS41_15165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CVS41_15170	COG3115	cell septum assembly
CVS41_15175	COG1196	nuclear chromosome segregation
CVS41_15185	COG2860	membrane
CVS41_15195	COG3108	Peptidase M15
CVS41_15200	COG2989	Protein conserved in bacteria
CVS41_15215	COG0463	Glycosyl transferase, family 2
CVS41_15230	COG0366	Alpha amylase catalytic
CVS41_15265	COG2199	diguanylate cyclase activity
CVS41_15265	COG2203	Gaf domain
CVS41_15275	COG3590	peptidase
CVS41_15285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CVS41_15290	COG1982	Orn Lys Arg decarboxylase major
CVS41_15295	COG0531	amino acid
CVS41_15300	COG3710	Transcriptional regulator
CVS41_15305	COG0531	amino acid
CVS41_15325	COG0814	amino acid
CVS41_15355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CVS41_15360	COG0739	heme binding
CVS41_15365	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CVS41_15375	COG0251	oxidation-reduction process
CVS41_15390	COG0583	DNA-binding transcription factor activity
CVS41_15405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CVS41_15415	COG3091	SprT-like family
CVS41_15425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CVS41_15430	COG0189	ligase activity
CVS41_15435	COG1678	Uncharacterized ACR, COG1678
CVS41_15440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CVS41_15445	COG3104	oligopeptide transport
CVS41_15450	COG0583	DNA-binding transcription factor activity
CVS41_15460	COG0714	Associated with various cellular activities
CVS41_15475	COG1115	amino acid carrier protein
CVS41_15480	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CVS41_15490	COG0825	malonyl-CoA metabolic process
CVS41_15500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CVS41_15505	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_15510	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_15515	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CVS41_15520	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CVS41_15530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CVS41_15535	COG0750	zinc metalloprotease
CVS41_15540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CVS41_15545	COG0575	Belongs to the CDS family
CVS41_15555	COG0233	cytoplasmic translational termination
CVS41_15560	COG0528	UMP kinase activity
CVS41_15565	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CVS41_15570	COG0052	Belongs to the universal ribosomal protein uS2 family
CVS41_15575	COG0024	Methionine aminopeptidase
CVS41_15585	COG2171	N-acyltransferase activity
CVS41_15595	COG1263	PTS System
CVS41_15595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_15605	COG4580	involved in the transport of maltose and maltodextrins
CVS41_15615	COG0564	pseudouridine synthase activity
CVS41_15620	COG3098	single-species biofilm formation
CVS41_15645	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CVS41_15655	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CVS41_15655	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CVS41_15665	COG3706	GGDEF domain
CVS41_15670	COG1611	Belongs to the LOG family
CVS41_15675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CVS41_15680	COG0473	3-isopropylmalate dehydrogenase activity
CVS41_15690	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
CVS41_15695	COG2363	Small membrane protein
CVS41_15705	COG0583	DNA-binding transcription factor activity
CVS41_15710	COG0840	transmembrane signaling receptor activity
CVS41_15715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CVS41_15730	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CVS41_15735	COG1666	GTP binding
CVS41_15740	COG3248	Nucleoside-binding outer membrane protein
CVS41_15750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CVS41_15760	COG2813	Specifically methylates the guanine in position
CVS41_15765	COG0271	Belongs to the BolA IbaG family
CVS41_15770	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_15775	COG1805	sodium ion transport
CVS41_15785	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_15790	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CVS41_15795	COG2871	sodium ion transport
CVS41_15800	COG1477	protein flavinylation
CVS41_15830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CVS41_15845	COG0300	oxidoreductase activity
CVS41_15855	COG0415	Belongs to the DNA photolyase family
CVS41_15860	COG0789	Transcriptional regulator
CVS41_15865	COG3272	Protein of unknown function (DUF1722)
CVS41_15895	COG1605	Chorismate mutase
CVS41_15895	COG0077	Prephenate dehydratase
CVS41_15955	COG2801	Transposase and inactivated derivatives
CVS41_15960	COG0840	transmembrane signaling receptor activity
CVS41_15970	COG4584	PFAM Integrase catalytic
CVS41_15975	COG1484	DNA-dependent DNA replication
CVS41_15990	COG5377	YqaJ viral recombinase family
CVS41_16035	COG2003	Belongs to the UPF0758 family
CVS41_16050	COG0469	pyruvate kinase activity
CVS41_16060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_16060	COG1263	PTS System
CVS41_16065	COG1874	Beta-galactosidase
CVS41_16070	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CVS41_16075	COG3833	ABC-type maltose transport systems, permease component
CVS41_16080	COG1175	transmembrane transport
CVS41_16085	COG2182	Extracellular solute-binding protein
CVS41_16110	COG4580	involved in the transport of maltose and maltodextrins
CVS41_16115	COG1609	Transcriptional regulator
CVS41_16120	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CVS41_16125	COG1085	galactose-1-phosphate uridylyltransferase
CVS41_16130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CVS41_16170	COG0840	transmembrane signaling receptor activity
CVS41_16180	COG0300	oxidoreductase activity
CVS41_16205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CVS41_16250	COG0826	peptidase U32
CVS41_16255	COG1280	lysine exporter protein (LysE YggA)
CVS41_16285	COG0643	Histidine kinase
CVS41_16285	COG2198	Histidine kinase
CVS41_16295	COG0835	chemotaxis
CVS41_16300	COG0840	transmembrane signaling receptor activity
CVS41_16310	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CVS41_16315	COG2201	protein-glutamate methylesterase activity
CVS41_16320	COG1185	polyribonucleotide nucleotidyltransferase activity
CVS41_16325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CVS41_16330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CVS41_16335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CVS41_16340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CVS41_16345	COG0195	Participates in both transcription termination and antitermination
CVS41_16350	COG0779	Required for maturation of 30S ribosomal subunits
CVS41_16365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CVS41_16370	COG0149	triose-phosphate isomerase activity
CVS41_16375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CVS41_16380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CVS41_16385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_16390	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CVS41_16395	COG1534	Rna-binding protein
CVS41_16405	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CVS41_16410	COG1360	Flagellar Motor Protein
CVS41_16415	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CVS41_16420	COG1722	exodeoxyribonuclease VII activity
CVS41_16425	COG0142	geranyltranstransferase activity
CVS41_16430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CVS41_16435	COG0737	Belongs to the 5'-nucleotidase family
CVS41_16455	COG2204	response regulator
CVS41_16460	COG0545	Peptidyl-prolyl cis-trans isomerase
CVS41_16470	COG2900	Belongs to the SlyX family
CVS41_16500	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CVS41_16505	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CVS41_16510	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CVS41_16515	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CVS41_16530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CVS41_16530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CVS41_16535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CVS41_16545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CVS41_16555	COG0784	Response regulator, receiver
CVS41_16555	COG2205	protein histidine kinase activity
CVS41_16555	COG2198	Histidine kinase
CVS41_16560	COG1879	ABC-type sugar transport system periplasmic component
CVS41_16570	COG0745	RESPONSE REGULATOR receiver
CVS41_16575	COG3005	denitrification pathway
CVS41_16585	COG3381	protein complex oligomerization
CVS41_16605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CVS41_16610	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CVS41_16615	COG0511	ligase activity, forming carbon-carbon bonds
CVS41_16620	COG0439	Biotin carboxylase
CVS41_16630	COG4145	pantothenate transmembrane transporter activity
CVS41_16635	COG2190	(PTS) system
CVS41_16635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_16635	COG1263	PTS System
CVS41_16640	COG0583	DNA-binding transcription factor activity
CVS41_16645	COG0604	alcohol dehydrogenase
CVS41_16650	COG2264	protein methyltransferase activity
CVS41_16655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CVS41_16665	COG0778	Nitroreductase
CVS41_16670	COG1902	pentaerythritol trinitrate reductase activity
CVS41_16670	COG0446	pyridine nucleotide-disulphide oxidoreductase
CVS41_16675	COG0616	signal peptide processing
CVS41_16695	COG0848	biopolymer transport protein
CVS41_16700	COG0811	peptide transport
CVS41_16705	COG0811	peptide transport
CVS41_16720	COG4174	ABC transporter (Permease)
CVS41_16725	COG4239	(ABC) transporter, permease
CVS41_16735	COG0444	Belongs to the ABC transporter superfamily
CVS41_16740	COG4608	Belongs to the ABC transporter superfamily
CVS41_16760	COG3416	Protein conserved in bacteria
CVS41_16770	COG0741	lytic transglycosylase activity
CVS41_16785	COG0488	(ABC) transporter
CVS41_16795	COG2252	PERMEase
CVS41_16800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_16805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CVS41_16810	COG0840	transmembrane signaling receptor activity
CVS41_16820	COG1278	Cold shock
CVS41_16860	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CVS41_16865	COG1162	GTPase activity
CVS41_16870	COG0688	phosphatidylethanolamine metabolic process
CVS41_16875	COG4628	conserved protein (DUF2132)
CVS41_16890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CVS41_16910	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CVS41_16920	COG2195	Cleaves the N-terminal amino acid of tripeptides
CVS41_16925	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CVS41_16930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CVS41_16935	COG3178	'Phosphotransferase
CVS41_16940	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CVS41_16945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CVS41_16950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CVS41_16955	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CVS41_16965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CVS41_16980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CVS41_16995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CVS41_17000	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CVS41_17005	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CVS41_17010	COG0142	geranyltranstransferase activity
CVS41_17015	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CVS41_17020	COG0330	HflC and HflK could
CVS41_17025	COG0330	HflC and HflK could
CVS41_17030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CVS41_17035	COG1923	regulation of RNA biosynthetic process
CVS41_17040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CVS41_17045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CVS41_17050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CVS41_17060	COG0802	atpase or kinase
CVS41_17065	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CVS41_17065	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CVS41_17085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CVS41_17090	COG2011	ABC-type metal ion transport system permease component
CVS41_17095	COG1464	Belongs to the NlpA lipoprotein family
CVS41_17130	COG2198	Histidine kinase
CVS41_17130	COG0784	Response regulator, receiver
CVS41_17130	COG5002	protein histidine kinase activity
CVS41_17165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CVS41_17170	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CVS41_17175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVS41_17180	COG2716	regulation of RNA biosynthetic process
CVS41_17185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CVS41_17190	COG3013	Belongs to the UPF0304 family
CVS41_17195	COG3092	negative regulation of chromosome organization
CVS41_17200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CVS41_17205	COG0280	phosphate acetyltransferase
CVS41_17205	COG0857	belongs to the CobB CobQ family
CVS41_17210	COG1555	photosystem II stabilization
CVS41_17215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CVS41_17220	COG3104	oligopeptide transport
CVS41_17225	COG0745	RESPONSE REGULATOR receiver
CVS41_17255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CVS41_17270	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CVS41_17305	COG0440	acetolactate synthase activity
CVS41_17310	COG0028	Belongs to the TPP enzyme family
CVS41_17335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CVS41_17340	COG0473	3-isopropylmalate dehydrogenase activity
CVS41_17345	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CVS41_17350	COG0066	3-isopropylmalate dehydratase activity
CVS41_17365	COG4143	(ABC) transporter
CVS41_17370	COG1178	ABC-type Fe3 transport system permease component
CVS41_17375	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CVS41_17380	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CVS41_17430	COG0459	protein refolding
CVS41_17435	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CVS41_17445	COG3030	protein affecting phage T7 exclusion by the F plasmid
CVS41_17450	COG1027	Aspartate ammonia-lyase
CVS41_17455	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CVS41_17460	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CVS41_17465	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CVS41_17470	COG1610	YqeY-like protein
CVS41_17475	COG0358	DNA primase activity
CVS41_17480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CVS41_17525	COG1609	Transcriptional regulator
CVS41_17535	COG0840	transmembrane signaling receptor activity
CVS41_17550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVS41_17555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVS41_17555	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CVS41_17560	COG2723	6-phospho-beta-galactosidase activity
CVS41_17565	COG1447	Phosphotransferase system cellobiose-specific component IIA
CVS41_17600	COG0305	Participates in initiation and elongation during chromosome replication
CVS41_17630	COG0151	Belongs to the GarS family
CVS41_17635	COG0138	bifunctional purine biosynthesis protein purh
CVS41_17645	COG3036	rescue of stalled ribosome
CVS41_17650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CVS41_17655	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CVS41_17665	COG0673	inositol 2-dehydrogenase activity
CVS41_17675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVS41_17680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CVS41_17690	COG0583	DNA-binding transcription factor activity
CVS41_17695	COG0477	Major facilitator Superfamily
CVS41_17710	COG1028	Short-chain dehydrogenase reductase Sdr
CVS41_17715	COG3706	GGDEF domain
CVS41_17715	COG0745	RESPONSE REGULATOR receiver
CVS41_17735	COG0456	acetyltransferase
CVS41_17745	COG1022	Amp-dependent synthetase and ligase
CVS41_17750	COG2918	glutathione biosynthetic process
CVS41_17755	COG0612	Peptidase, M16
CVS41_17760	COG1238	metal cluster binding
CVS41_17790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_17795	COG0359	binds to the 23S rRNA
CVS41_17800	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CVS41_17805	COG0360	Binds together with S18 to 16S ribosomal RNA
CVS41_17810	COG1914	H( )-stimulated, divalent metal cation uptake system
CVS41_17815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CVS41_17825	COG0776	regulation of translation
CVS41_17840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CVS41_17855	COG0560	Phosphoserine phosphatase
CVS41_17865	COG0813	purine-nucleoside phosphorylase activity
CVS41_17870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CVS41_17875	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CVS41_17880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CVS41_17890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_17895	COG0084	hydrolase, TatD family'
CVS41_17900	COG4968	Prepilin-type N-terminal cleavage methylation domain
CVS41_17910	COG1854	S-ribosylhomocysteine lyase activity
CVS41_17925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVS41_17925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CVS41_17985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CVS41_17990	COG1047	Peptidyl-prolyl cis-trans
CVS41_17995	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CVS41_18000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CVS41_18005	COG0196	riboflavin kinase activity
CVS41_18010	COG0728	peptidoglycan biosynthetic process
CVS41_18015	COG0268	Binds directly to 16S ribosomal RNA
CVS41_18020	COG0640	Transcriptional regulator
CVS41_18025	COG0583	DNA-binding transcription factor activity
CVS41_18035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVS41_18040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CVS41_18045	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CVS41_18055	COG1051	belongs to the nudix hydrolase family
CVS41_18060	COG3066	DNA modification
CVS41_18070	COG0335	large ribosomal subunit rRNA binding
CVS41_18075	COG0336	Belongs to the RNA methyltransferase TrmD family
CVS41_18080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CVS41_18085	COG0228	four-way junction DNA binding
CVS41_18090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CVS41_18095	COG4137	Cytochrome C assembly protein
CVS41_18100	COG4536	flavin adenine dinucleotide binding
CVS41_18110	COG1017	nitric oxide dioxygenase activity
CVS41_18110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CVS41_18115	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CVS41_18120	COG0039	L-malate dehydrogenase activity
CVS41_18125	COG4160	amino acid transport
CVS41_18130	COG4215	(ABC) transporter
CVS41_18135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CVS41_18140	COG1126	abc transporter atp-binding protein
CVS41_18145	COG1438	arginine binding
CVS41_18150	COG2837	iron assimilation
CVS41_18155	COG3842	ATPase activity
CVS41_18165	COG1840	ABC-type Fe3 transport system, periplasmic component
CVS41_18170	COG0347	Belongs to the P(II) protein family
CVS41_18190	COG3022	response to hydroperoxide
CVS41_18205	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CVS41_18210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CVS41_18215	COG0762	integral membrane protein
CVS41_18220	COG1872	DUF167
CVS41_18230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CVS41_18235	COG0583	DNA-binding transcription factor activity
CVS41_18250	COG1929	Belongs to the glycerate kinase type-1 family
CVS41_18255	COG2610	gluconate transmembrane transporter activity
CVS41_18260	COG3835	regulator
CVS41_18265	COG3112	Uncharacterised protein family (UPF0231)
CVS41_18285	COG0513	Belongs to the DEAD box helicase family
CVS41_18325	COG3118	belongs to the thioredoxin family
CVS41_18325	COG0457	Tetratricopeptide repeat
CVS41_18335	COG1215	transferase activity, transferring glycosyl groups
CVS41_18340	COG1215	transferase activity, transferring glycosyl groups
CVS41_18355	COG2194	sulfuric ester hydrolase activity
CVS41_18360	COG1448	Aminotransferase
CVS41_18375	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CVS41_18380	COG1328	CTP reductase activity
CVS41_18405	COG0543	2 iron, 2 sulfur cluster binding
CVS41_18405	COG0633	Ferredoxin
CVS41_18420	COG1215	transferase activity, transferring glycosyl groups
CVS41_18425	COG0726	polysaccharide deacetylase
CVS41_18425	COG1649	PFAM Uncharacterised BCR, COG1649
CVS41_18440	COG0840	transmembrane signaling receptor activity
CVS41_18445	COG3397	chitin binding
CVS41_18450	COG3174	membrane
CVS41_18455	COG0110	maltose O-acetyltransferase activity
CVS41_18470	COG1011	Hydrolase
CVS41_18475	COG0494	nUDIX hydrolase
CVS41_18480	COG1218	3'(2'),5'-bisphosphate nucleotidase
CVS41_18485	COG0814	amino acid
CVS41_18490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CVS41_18505	COG0626	cystathionine gamma-synthase activity
CVS41_18510	COG0527	aspartate kinase activity
CVS41_18510	COG0460	homoserine dehydrogenase
CVS41_18515	COG0306	phosphate transporter
CVS41_18520	COG1392	Phosphate transport regulator
CVS41_18530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CVS41_18535	COG2813	Specifically methylates the guanine in position
CVS41_18540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CVS41_18545	COG0297	glycogen (starch) synthase activity
CVS41_18585	COG1757	Na H antiporter
CVS41_18590	COG0316	Belongs to the HesB IscA family
CVS41_18600	COG0038	chloride channel
CVS41_18605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CVS41_18620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CVS41_18620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CVS41_18650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CVS41_18655	COG0564	pseudouridine synthase activity
CVS41_18665	COG0110	maltose O-acetyltransferase activity
CVS41_18670	COG0366	Alpha amylase catalytic
CVS41_18675	COG1263	PTS System
CVS41_18675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CVS41_18680	COG1609	Transcriptional regulator
CVS41_18695	COG0252	asparaginase activity
CVS41_18700	COG1253	flavin adenine dinucleotide binding
CVS41_18705	COG0586	Pfam SNARE associated Golgi protein
CVS41_18710	COG1686	Belongs to the peptidase S11 family
CVS41_18745	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CVS41_18750	COG0527	aspartate kinase activity
CVS41_18755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CVS41_18765	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CVS41_18785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CVS41_18835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CVS41_18860	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CVS41_18865	COG4667	esterase of the alpha-beta hydrolase superfamily
CVS41_18875	COG1346	cytolysis
CVS41_18880	COG1380	Effector of murein hydrolase LrgA
CVS41_18885	COG0583	DNA-binding transcription factor activity
CVS41_18900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CVS41_18920	COG2131	deaminase
CVS41_18925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CVS41_18930	COG2022	thiamine diphosphate biosynthetic process
CVS41_18940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CVS41_18945	COG0352	thiamine-phosphate diphosphorylase activity
CVS41_18950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CVS41_18970	COG0745	RESPONSE REGULATOR receiver
CVS41_18980	COG0189	ligase activity
CVS41_19025	COG0477	Major facilitator Superfamily
CVS41_19040	COG0312	modulator of DNA gyrase
CVS41_19045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CVS41_19060	COG3164	Protein of unknown function
CVS41_19065	COG1530	ribonuclease E activity
CVS41_19070	COG0424	maF-like protein
CVS41_19075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CVS41_19080	COG1792	Involved in formation and maintenance of cell shape
CVS41_19085	COG1077	Cell shape determining protein MreB Mrl
CVS41_19130	COG1459	type II secretion system
CVS41_19135	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CVS41_19180	COG2199	diguanylate cyclase activity
CVS41_19180	COG2200	EAL domain
CVS41_19185	COG2200	EAL domain
CVS41_19190	COG0387	Pfam Sodium calcium exchanger
CVS41_19195	COG2986	histidine ammonia-lyase
CVS41_19200	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CVS41_19205	COG0010	Belongs to the arginase family
CVS41_19210	COG1228	amidohydrolase
CVS41_19215	COG2188	Transcriptional regulator
CVS41_19220	COG0288	reversible hydration of carbon dioxide
CVS41_19230	COG2177	Part of the ABC transporter FtsEX involved in
CVS41_19235	COG2884	Cell division ATP-binding protein ftsE
CVS41_19240	COG0552	protein localization to endoplasmic reticulum
CVS41_19245	COG0742	ribosomal rna small subunit methyltransferase
CVS41_19270	COG2249	NAD(P)H dehydrogenase (quinone) activity
CVS41_19275	COG0583	DNA-binding transcription factor activity
CVS41_19280	COG4221	oxidoreductase activity
CVS41_19295	COG1770	oligopeptidase
CVS41_19310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CVS41_19315	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CVS41_19325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CVS41_19335	COG2095	MarC family integral membrane protein
CVS41_19345	COG1301	dicarboxylic acid transport
CVS41_19370	COG3714	YhhN family
CVS41_19430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CVS41_19435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CVS41_19440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CVS41_19445	COG0049	tRNA binding
CVS41_19450	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CVS41_19455	COG2168	tRNA wobble position uridine thiolation
CVS41_19460	COG2923	Belongs to the DsrF TusC family
CVS41_19465	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CVS41_19475	COG2964	Protein conserved in bacteria
CVS41_19480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CVS41_19485	COG0085	RNA polymerase activity
CVS41_19490	COG0222	ribosome binding
CVS41_19495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CVS41_19500	COG0081	regulation of translation
CVS41_19505	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CVS41_19510	COG0250	Participates in transcription elongation, termination and antitermination
CVS41_19515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity