locus-tag	class	description
NBH81_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NBH81_00010	COG0592	DNA-directed DNA polymerase activity
NBH81_00020	COG0187	DNA topoisomerase II activity
NBH81_00030	COG2378	regulation of single-species biofilm formation
NBH81_00040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NBH81_00045	COG0071	Belongs to the small heat shock protein (HSP20) family
NBH81_00050	COG0071	Belongs to the small heat shock protein (HSP20) family
NBH81_00055	COG3977	Valine--pyruvate aminotransferase
NBH81_00070	COG2814	Major facilitator Superfamily
NBH81_00075	COG0745	RESPONSE REGULATOR receiver
NBH81_00080	COG2205	protein histidine kinase activity
NBH81_00100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NBH81_00105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_00105	COG4191	Histidine kinase
NBH81_00110	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBH81_00115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBH81_00120	COG1309	transcriptional regulator
NBH81_00150	COG0561	phosphatase activity
NBH81_00155	COG2267	carboxylic ester hydrolase activity
NBH81_00165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBH81_00170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBH81_00175	COG1758	RNA polymerase activity
NBH81_00185	COG0859	PFAM glycosyl transferase family 9
NBH81_00190	COG3642	lipopolysaccharide core region biosynthetic process
NBH81_00230	COG0589	response to stress
NBH81_00235	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NBH81_00240	COG1528	Iron-storage protein
NBH81_00245	COG2081	HI0933 family
NBH81_00250	COG3275	phosphorelay sensor kinase activity
NBH81_00255	COG3279	Response regulator of the LytR AlgR family
NBH81_00260	COG2223	nitrite transmembrane transporter activity
NBH81_00265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NBH81_00270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NBH81_00285	COG0583	DNA-binding transcription factor activity
NBH81_00290	COG4206	TonB-dependent receptor
NBH81_00295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NBH81_00330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NBH81_00335	COG2166	iron-sulfur cluster assembly
NBH81_00340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NBH81_00355	COG3245	cytochrome
NBH81_00360	COG1063	alcohol dehydrogenase
NBH81_00375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NBH81_00385	COG0110	maltose O-acetyltransferase activity
NBH81_00395	COG3307	-O-antigen
NBH81_00440	COG1280	lysine exporter protein (LysE YggA)
NBH81_00490	COG0210	DNA helicase
NBH81_00495	COG1744	ABC transporter substrate-binding protein PnrA-like
NBH81_00500	COG3845	ABC transporter
NBH81_00505	COG4603	Belongs to the binding-protein-dependent transport system permease family
NBH81_00510	COG1079	Belongs to the binding-protein-dependent transport system permease family
NBH81_00515	COG2239	Acts as a magnesium transporter
NBH81_00520	COG1648	precorrin-2 dehydrogenase activity
NBH81_00520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NBH81_00525	COG2116	formate transmembrane transporter activity
NBH81_00535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NBH81_00540	COG0842	Transport permease protein
NBH81_00545	COG0842	Transport permease protein
NBH81_00550	COG1131	(ABC) transporter
NBH81_00555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBH81_00565	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NBH81_00570	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NBH81_00580	COG0018	arginyl-trna synthetase
NBH81_00590	COG1595	DNA-templated transcription, initiation
NBH81_00600	COG1968	undecaprenyl-diphosphatase activity
NBH81_00605	COG2017	converts alpha-aldose to the beta-anomer
NBH81_00610	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NBH81_00615	COG1085	galactose-1-phosphate uridylyltransferase
NBH81_00620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NBH81_00625	COG1609	Transcriptional regulator
NBH81_00630	COG3250	beta-galactosidase activity
NBH81_00640	COG1129	ABC transporter
NBH81_00645	COG4211	Belongs to the binding-protein-dependent transport system permease family
NBH81_00655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBH81_00670	COG0366	Alpha amylase catalytic
NBH81_00685	COG0443	Heat shock 70 kDa protein
NBH81_00690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBH81_00695	COG3045	CreA protein
NBH81_00715	COG0174	glutamine synthetase
NBH81_00735	COG3842	ATPase activity
NBH81_00740	COG1176	ABC-type spermidine putrescine transport system, permease component I
NBH81_00745	COG1177	transmembrane transport
NBH81_00750	COG2258	MOSC domain
NBH81_00850	COG2050	protein possibly involved in aromatic compounds catabolism
NBH81_00855	COG0514	ATP-dependent DNA helicase (RecQ)
NBH81_00865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NBH81_00875	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NBH81_00880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NBH81_00895	COG0254	rRNA binding
NBH81_00900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NBH81_00910	COG0702	epimerase
NBH81_00915	COG0814	amino acid
NBH81_00920	COG0281	malic enzyme
NBH81_00925	COG1295	ribonuclease BN
NBH81_00930	COG1490	D-aminoacyl-tRNA deacylase activity
NBH81_00940	COG0456	acetyltransferase
NBH81_00950	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NBH81_00955	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBH81_00960	COG2610	gluconate transmembrane transporter activity
NBH81_00965	COG3265	gluconokinase activity
NBH81_00970	COG0129	dihydroxy-acid dehydratase activity
NBH81_00975	COG0800	Aldolase
NBH81_00980	COG1609	Transcriptional regulator
NBH81_00990	COG4942	peptidase
NBH81_00995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NBH81_01000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBH81_01005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NBH81_01010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NBH81_01015	COG0316	Belongs to the HesB IscA family
NBH81_01015	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NBH81_01020	COG1040	competence protein
NBH81_01025	COG0596	Alpha beta hydrolase
NBH81_01045	COG2183	response to ionizing radiation
NBH81_01050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NBH81_01070	COG0051	transcription antitermination factor activity, RNA binding
NBH81_01075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NBH81_01080	COG0088	Forms part of the polypeptide exit tunnel
NBH81_01085	COG0089	rRNA binding
NBH81_01090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NBH81_01095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NBH81_01100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NBH81_01105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NBH81_01110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NBH81_01115	COG0255	Belongs to the universal ribosomal protein uL29 family
NBH81_01120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NBH81_01125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NBH81_01130	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NBH81_01135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NBH81_01140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NBH81_01145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NBH81_01150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NBH81_01155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NBH81_01160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NBH81_01165	COG1841	ribosomal large subunit assembly
NBH81_01170	COG0200	Binds to the 23S rRNA
NBH81_01175	COG0201	protein transport
NBH81_01180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NBH81_01185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NBH81_01190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NBH81_01195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NBH81_01200	COG0202	RNA polymerase activity
NBH81_01205	COG0203	ribosomal protein L17
NBH81_01235	COG4771	TonB-dependent receptor
NBH81_01275	COG0583	DNA-binding transcription factor activity
NBH81_01285	COG1741	Belongs to the pirin family
NBH81_01290	COG2259	Doxx family
NBH81_01295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NBH81_01300	COG1074	ATP-dependent DNA helicase activity
NBH81_01305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NBH81_01350	COG1175	transmembrane transport
NBH81_01360	COG3842	ATPase activity
NBH81_01390	COG2873	o-acetylhomoserine
NBH81_01420	COG5380	lipid catabolic process
NBH81_01425	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NBH81_01430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NBH81_01455	COG0753	catalase activity
NBH81_01460	COG0456	acetyltransferase
NBH81_01460	COG0454	-acetyltransferase
NBH81_01485	COG2927	DNA polymerase III (CHI subunit)
NBH81_01490	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NBH81_01495	COG0795	lipopolysaccharide-transporting ATPase activity
NBH81_01500	COG0795	lipopolysaccharide-transporting ATPase activity
NBH81_01515	COG0582	viral genome integration into host DNA
NBH81_01625	COG1494	fructose-1,6-bisphosphatase
NBH81_01640	COG2959	enzyme of heme biosynthesis
NBH81_01650	COG0181	hydroxymethylbilane synthase activity
NBH81_01655	COG3072	Adenylate cyclase
NBH81_01660	COG0400	carboxylic ester hydrolase activity
NBH81_01665	COG1965	Belongs to the frataxin family
NBH81_01675	COG0019	diaminopimelate decarboxylase activity
NBH81_01680	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NBH81_01695	COG1011	Hydrolase
NBH81_01705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NBH81_01715	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NBH81_01720	COG3028	Belongs to the UPF0307 family
NBH81_01725	COG0312	modulator of DNA gyrase
NBH81_01730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NBH81_01735	COG5007	Belongs to the BolA IbaG family
NBH81_01745	COG2854	intermembrane phospholipid transfer
NBH81_01750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NBH81_01755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NBH81_01760	COG1127	ABC transporter
NBH81_01765	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NBH81_01765	COG0517	IMP dehydrogenase activity
NBH81_01770	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NBH81_01775	COG3117	lipopolysaccharide transmembrane transporter activity
NBH81_01780	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NBH81_01785	COG1137	ATPase activity
NBH81_01800	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_01805	COG1660	Displays ATPase and GTPase activities
NBH81_01810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_01815	COG3711	transcriptional antiterminator
NBH81_01815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_01830	COG3964	amidohydrolase
NBH81_01860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NBH81_01865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NBH81_01875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NBH81_01880	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NBH81_01885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NBH81_01890	COG0723	plastoquinol--plastocyanin reductase activity
NBH81_01895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NBH81_01900	COG2857	Cytochrome c1
NBH81_01905	COG0625	glutathione transferase activity
NBH81_01910	COG2969	positive regulation of protein catabolic process
NBH81_01915	COG2823	Periplasmic or secreted lipoprotein
NBH81_01920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NBH81_01925	COG0792	nuclease activity
NBH81_01930	COG3107	peptidoglycan biosynthetic process
NBH81_01935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NBH81_01960	COG1987	bacterial-type flagellum assembly
NBH81_01985	COG1677	Flagellar hook-basal body complex protein FliE
NBH81_01995	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NBH81_02030	COG1815	bacterial-type flagellum-dependent cell motility
NBH81_02050	COG4787	bacterial-type flagellum-dependent cell motility
NBH81_02055	COG4786	Flagellar basal body rod
NBH81_02060	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NBH81_02065	COG1706	bacterial-type flagellum-dependent cell motility
NBH81_02080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NBH81_02095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NBH81_02100	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NBH81_02125	COG1191	sigma factor activity
NBH81_02130	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NBH81_02145	COG1388	LysM domain
NBH81_02145	COG0741	lytic transglycosylase activity
NBH81_02150	COG2001	Belongs to the MraZ family
NBH81_02155	COG0275	rRNA processing
NBH81_02160	COG3116	cell division
NBH81_02165	COG0768	penicillin binding
NBH81_02175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NBH81_02180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NBH81_02185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NBH81_02190	COG0772	Belongs to the SEDS family
NBH81_02195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NBH81_02200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NBH81_02210	COG0849	cell division
NBH81_02215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NBH81_02220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NBH81_02230	COG0653	protein targeting
NBH81_02235	COG0494	nUDIX hydrolase
NBH81_02240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NBH81_02245	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NBH81_02260	COG1459	type II secretion system
NBH81_02265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NBH81_02290	COG2186	Transcriptional regulator
NBH81_02295	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NBH81_02300	COG0508	dehydrogenase complex catalyzes the overall conversion of
NBH81_02305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NBH81_02315	COG0840	transmembrane signaling receptor activity
NBH81_02320	COG1752	Esterase of the alpha-beta hydrolase superfamily
NBH81_02325	COG1049	propionate catabolic process, 2-methylcitrate cycle
NBH81_02340	COG0523	cobalamin synthesis protein
NBH81_02345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBH81_02360	COG2814	Major facilitator Superfamily
NBH81_02375	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NBH81_02380	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NBH81_02405	COG3314	Sporulation integral membrane protein YlbJ
NBH81_02465	COG2314	TM2 domain
NBH81_02515	COG3314	Sporulation integral membrane protein YlbJ
NBH81_02535	COG0165	Argininosuccinate lyase
NBH81_02540	COG0137	argininosuccinate synthase activity
NBH81_02550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NBH81_02555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NBH81_02565	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NBH81_02580	COG3706	GGDEF domain
NBH81_02585	COG0814	amino acid
NBH81_02590	COG3932	Exopolysaccharide synthesis, ExoD
NBH81_02600	COG3706	GGDEF domain
NBH81_02605	COG0004	ammonium transporteR
NBH81_02610	COG3133	Outer membrane lipoprotein
NBH81_02615	COG0456	acetyltransferase
NBH81_02635	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NBH81_02640	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NBH81_02655	COG0494	nUDIX hydrolase
NBH81_02660	COG0628	permease
NBH81_02680	COG3284	Transcriptional regulator
NBH81_02690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBH81_02690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_02690	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
NBH81_02695	COG1461	Dihydroxyacetone kinase
NBH81_02700	COG2376	Dihydroxyacetone kinase
NBH81_02705	COG2252	PERMEase
NBH81_02710	COG1278	Cold shock
NBH81_02720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NBH81_02735	COG0629	single-stranded DNA binding
NBH81_02740	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NBH81_02755	COG3047	cAMP biosynthetic process
NBH81_02760	COG0840	transmembrane signaling receptor activity
NBH81_02785	COG3135	benzoate transporter
NBH81_02790	COG1396	sequence-specific DNA binding
NBH81_02825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NBH81_02825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NBH81_02840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NBH81_02845	COG0038	chloride channel
NBH81_02855	COG0316	Belongs to the HesB IscA family
NBH81_02860	COG1757	Na H antiporter
NBH81_02900	COG0297	glycogen (starch) synthase activity
NBH81_02905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NBH81_02910	COG2813	Specifically methylates the guanine in position
NBH81_02915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBH81_02925	COG1392	Phosphate transport regulator
NBH81_02930	COG0306	phosphate transporter
NBH81_02935	COG0527	aspartate kinase activity
NBH81_02935	COG0460	homoserine dehydrogenase
NBH81_02940	COG0626	cystathionine gamma-synthase activity
NBH81_02950	COG2207	Transcriptional regulator
NBH81_02950	COG3708	Transcriptional regulator
NBH81_02955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBH81_02960	COG0814	amino acid
NBH81_02965	COG1218	3'(2'),5'-bisphosphate nucleotidase
NBH81_02970	COG0494	nUDIX hydrolase
NBH81_02975	COG1011	Hydrolase
NBH81_02990	COG0110	maltose O-acetyltransferase activity
NBH81_02995	COG3174	membrane
NBH81_03000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NBH81_03010	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NBH81_03015	COG4208	sulfate ABC transporter
NBH81_03020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NBH81_03025	COG0583	DNA-binding transcription factor activity
NBH81_03030	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NBH81_03035	COG0765	amino acid transport
NBH81_03045	COG1126	abc transporter atp-binding protein
NBH81_03050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_03055	COG3397	chitin binding
NBH81_03060	COG0840	transmembrane signaling receptor activity
NBH81_03075	COG0726	polysaccharide deacetylase
NBH81_03075	COG1649	PFAM Uncharacterised BCR, COG1649
NBH81_03080	COG1215	transferase activity, transferring glycosyl groups
NBH81_03095	COG0543	2 iron, 2 sulfur cluster binding
NBH81_03095	COG0633	Ferredoxin
NBH81_03120	COG1328	CTP reductase activity
NBH81_03125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBH81_03140	COG1448	Aminotransferase
NBH81_03155	COG1842	Phage shock protein A
NBH81_03170	COG2827	Endonuclease containing a URI domain
NBH81_03185	COG1573	uracil-dna glycosylase
NBH81_03190	COG0697	spore germination
NBH81_03195	COG0583	DNA-binding transcription factor activity
NBH81_03200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NBH81_03205	COG1121	(ABC) transporter
NBH81_03210	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NBH81_03230	COG0739	heme binding
NBH81_03240	COG3068	Protein conserved in bacteria
NBH81_03260	COG0617	tRNA 3'-terminal CCA addition
NBH81_03265	COG1194	a g-specific adenine glycosylase
NBH81_03270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NBH81_03280	COG3111	PFAM Bacterial OB fold (BOF) protein
NBH81_03285	COG3240	lipase activity
NBH81_03290	COG2885	chlorophyll binding
NBH81_03290	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NBH81_03295	COG3706	GGDEF domain
NBH81_03300	COG0557	exoribonuclease II activity
NBH81_03305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NBH81_03315	COG2153	protein acetylation
NBH81_03320	COG0513	Belongs to the DEAD box helicase family
NBH81_03325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NBH81_03350	COG0735	belongs to the Fur family
NBH81_03440	COG1846	Transcriptional regulator
NBH81_03535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NBH81_03595	COG2771	luxR family
NBH81_03625	COG4626	Terminase
NBH81_03625	COG1802	Transcriptional regulator
NBH81_03640	COG0616	signal peptide processing
NBH81_03680	COG4386	tail sheath protein
NBH81_03740	COG3299	homolog of phage Mu protein gp47
NBH81_03745	COG3778	Protein conserved in bacteria
NBH81_03775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBH81_03780	COG0840	transmembrane signaling receptor activity
NBH81_03790	COG4166	transmembrane transport
NBH81_03800	COG0110	maltose O-acetyltransferase activity
NBH81_03810	COG1024	Enoyl-CoA hydratase
NBH81_03825	COG4221	oxidoreductase activity
NBH81_03830	COG0442	prolyl-tRNA aminoacylation
NBH81_03835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBH81_03845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NBH81_03845	COG3008	intermembrane lipid transfer
NBH81_03850	COG2995	paraquat-inducible protein a
NBH81_03860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBH81_03870	COG3706	GGDEF domain
NBH81_03870	COG4251	negative regulation of phosphorylation
NBH81_03870	COG5001	Diguanylate cyclase
NBH81_03870	COG2203	Gaf domain
NBH81_03875	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NBH81_03885	COG3916	Acyl-homoserine-lactone synthase
NBH81_03890	COG2771	luxR family
NBH81_03900	COG0840	transmembrane signaling receptor activity
NBH81_03905	COG0632	four-way junction helicase activity
NBH81_03910	COG2255	four-way junction helicase activity
NBH81_03920	COG1294	oxidase, subunit
NBH81_03925	COG4890	Cyd operon protein YbgT
NBH81_03930	COG3790	cyd operon protein YbgE
NBH81_03935	COG0824	Thioesterase
NBH81_03940	COG0811	peptide transport
NBH81_03955	COG0823	Involved in the tonB-independent uptake of proteins
NBH81_03960	COG2885	chlorophyll binding
NBH81_03965	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NBH81_04030	COG0733	neurotransmitter:sodium symporter activity
NBH81_04040	COG0733	neurotransmitter:sodium symporter activity
NBH81_04055	COG0561	phosphatase activity
NBH81_04105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NBH81_04110	COG1640	4-alpha-glucanotransferase
NBH81_04115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NBH81_04120	COG0676	glucose-6-phosphate 1-epimerase activity
NBH81_04125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NBH81_04130	COG0840	transmembrane signaling receptor activity
NBH81_04135	COG1585	Membrane protein implicated in regulation of membrane protease activity
NBH81_04140	COG0330	HflC and HflK could
NBH81_04145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NBH81_04145	COG1648	precorrin-2 dehydrogenase activity
NBH81_04150	COG0175	sulfate reduction
NBH81_04155	COG2895	sulfate adenylyltransferase (ATP) activity
NBH81_04160	COG0471	metal ion transport
NBH81_04160	COG3273	potassium ion transport
NBH81_04165	COG0529	Catalyzes the synthesis of activated sulfate
NBH81_04175	COG1204	response to ionizing radiation
NBH81_04185	COG0840	transmembrane signaling receptor activity
NBH81_04205	COG1136	(ABC) transporter
NBH81_04220	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NBH81_04235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NBH81_04240	COG0784	Response regulator, receiver
NBH81_04240	COG3437	response regulator, receiver
NBH81_04250	COG2076	Multidrug Resistance protein
NBH81_04255	COG2076	Multidrug Resistance protein
NBH81_04260	COG0346	lactoylglutathione lyase activity
NBH81_04265	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NBH81_04270	COG1643	Atp-dependent helicase
NBH81_04280	COG1489	DNA binding
NBH81_04285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NBH81_04290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBH81_04300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NBH81_04305	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NBH81_04310	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NBH81_04320	COG1823	symporter activity
NBH81_04345	COG0842	Transport permease protein
NBH81_04350	COG1131	(ABC) transporter
NBH81_04365	COG0163	prenyltransferase activity
NBH81_04370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NBH81_04375	COG0671	phosphoesterase, PA-phosphatase related
NBH81_04380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NBH81_04385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NBH81_04390	COG1151	hydroxylamine reductase activity
NBH81_04395	COG0783	Belongs to the Dps family
NBH81_04400	COG3023	N-Acetylmuramoyl-L-alanine amidase
NBH81_04405	COG4807	Protein conserved in bacteria
NBH81_04415	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NBH81_04420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NBH81_04425	COG3956	TIGRFAM MazG family protein
NBH81_04430	COG0504	CTP synthase activity
NBH81_04435	COG0148	phosphopyruvate hydratase activity
NBH81_04480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NBH81_04490	COG0488	(ABC) transporter
NBH81_04510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBH81_04525	COG1794	racemase activity, acting on amino acids and derivatives
NBH81_04535	COG2731	YhcH YjgK YiaL family protein
NBH81_04545	COG0668	transmembrane transport
NBH81_04550	COG1376	ErfK ybiS ycfS ynhG family protein
NBH81_04560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NBH81_04565	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NBH81_04570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NBH81_04580	COG0585	pseudouridine synthase activity
NBH81_04585	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NBH81_04590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NBH81_04595	COG1238	metal cluster binding
NBH81_04610	COG1902	pentaerythritol trinitrate reductase activity
NBH81_04620	COG2852	Protein conserved in bacteria
NBH81_04630	COG2957	Belongs to the agmatine deiminase family
NBH81_04635	COG0154	amidase activity
NBH81_04665	COG0513	Belongs to the DEAD box helicase family
NBH81_04670	COG2199	diguanylate cyclase activity
NBH81_04670	COG2203	Gaf domain
NBH81_04680	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NBH81_04725	COG2816	NAD+ diphosphatase activity
NBH81_04735	COG4191	Histidine kinase
NBH81_04765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NBH81_04770	COG2252	PERMEase
NBH81_04780	COG0488	(ABC) transporter
NBH81_04795	COG0741	lytic transglycosylase activity
NBH81_04805	COG3416	Protein conserved in bacteria
NBH81_04825	COG4608	Belongs to the ABC transporter superfamily
NBH81_04830	COG0444	Belongs to the ABC transporter superfamily
NBH81_04840	COG4239	(ABC) transporter, permease
NBH81_04845	COG4174	ABC transporter (Permease)
NBH81_04855	COG0616	signal peptide processing
NBH81_04860	COG1902	pentaerythritol trinitrate reductase activity
NBH81_04860	COG0446	pyridine nucleotide-disulphide oxidoreductase
NBH81_04865	COG0778	Nitroreductase
NBH81_04875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBH81_04880	COG2264	protein methyltransferase activity
NBH81_04885	COG0604	alcohol dehydrogenase
NBH81_04890	COG0583	DNA-binding transcription factor activity
NBH81_04895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_04895	COG2190	(PTS) system
NBH81_04895	COG1263	PTS System
NBH81_04900	COG4145	pantothenate transmembrane transporter activity
NBH81_04910	COG0439	Biotin carboxylase
NBH81_04915	COG0511	ligase activity, forming carbon-carbon bonds
NBH81_04920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NBH81_04925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NBH81_04945	COG3381	protein complex oligomerization
NBH81_04955	COG3005	denitrification pathway
NBH81_04960	COG0745	RESPONSE REGULATOR receiver
NBH81_04970	COG1879	ABC-type sugar transport system periplasmic component
NBH81_04975	COG2198	Histidine kinase
NBH81_04975	COG2205	protein histidine kinase activity
NBH81_04975	COG0784	Response regulator, receiver
NBH81_04985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NBH81_04990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NBH81_04995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NBH81_04995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NBH81_05015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBH81_05020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NBH81_05025	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NBH81_05040	COG0601	transmembrane transport
NBH81_05050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NBH81_05055	COG0142	geranyltranstransferase activity
NBH81_05060	COG1722	exodeoxyribonuclease VII activity
NBH81_05065	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NBH81_05070	COG1360	Flagellar Motor Protein
NBH81_05085	COG1534	Rna-binding protein
NBH81_05090	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NBH81_05100	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NBH81_05105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NBH81_05110	COG0149	triose-phosphate isomerase activity
NBH81_05115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NBH81_05130	COG0779	Required for maturation of 30S ribosomal subunits
NBH81_05135	COG0195	Participates in both transcription termination and antitermination
NBH81_05140	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NBH81_05145	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NBH81_05150	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NBH81_05155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NBH81_05160	COG1185	polyribonucleotide nucleotidyltransferase activity
NBH81_05165	COG3655	Transcriptional regulator
NBH81_05175	COG0784	Response regulator, receiver
NBH81_05175	COG2205	protein histidine kinase activity
NBH81_05175	COG5002	protein histidine kinase activity
NBH81_05200	COG3397	chitin binding
NBH81_05240	COG0784	Response regulator, receiver
NBH81_05240	COG0835	chemotaxis
NBH81_05245	COG2755	lipolytic protein G-D-S-L family
NBH81_05250	COG4181	ATPase activity
NBH81_05255	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NBH81_05260	COG1090	epimerase
NBH81_05265	COG2200	EAL domain
NBH81_05270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBH81_05275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NBH81_05280	COG3171	Protein conserved in bacteria
NBH81_05285	COG2066	Belongs to the glutaminase family
NBH81_05290	COG2897	thiosulfate sulfurtransferase activity
NBH81_05305	COG0521	Mo-molybdopterin cofactor biosynthetic process
NBH81_05315	COG2966	Psort location CytoplasmicMembrane, score
NBH81_05325	COG3610	response to peptide
NBH81_05340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NBH81_05345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NBH81_05350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NBH81_05365	COG0786	glutamate:sodium symporter activity
NBH81_05370	COG0252	asparaginase activity
NBH81_05375	COG3139	Protein of unknown function (DUF1315)
NBH81_05395	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NBH81_05400	COG0321	lipoyl(octanoyl) transferase activity
NBH81_05405	COG2921	Belongs to the UPF0250 family
NBH81_05410	COG1686	Belongs to the peptidase S11 family
NBH81_05415	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NBH81_05420	COG2951	lytic endotransglycosylase activity
NBH81_05425	COG0772	Belongs to the SEDS family
NBH81_05430	COG0768	penicillin binding
NBH81_05435	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NBH81_05440	COG0799	negative regulation of ribosome biogenesis
NBH81_05445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NBH81_05460	COG0495	leucyl-tRNA aminoacylation
NBH81_05465	COG2888	peptidyl-tyrosine sulfation
NBH81_05470	COG0312	modulator of DNA gyrase
NBH81_05480	COG0716	FMN binding
NBH81_05485	COG4974	Belongs to the 'phage' integrase family
NBH81_05490	COG1970	mechanosensitive ion channel activity
NBH81_05505	COG0789	Transcriptional regulator
NBH81_05510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NBH81_05515	COG4535	Mg2 and Co2 transporter CorC
NBH81_05520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NBH81_05525	COG1702	phosphate starvation-inducible protein PhoH
NBH81_05530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NBH81_05535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBH81_05540	COG1335	isochorismatase
NBH81_05550	COG3706	GGDEF domain
NBH81_05555	COG0583	DNA-binding transcription factor activity
NBH81_05570	COG3069	C4-dicarboxylate transmembrane transporter activity
NBH81_05580	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NBH81_05585	COG0583	DNA-binding transcription factor activity
NBH81_05600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NBH81_05610	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NBH81_05620	COG0516	GMP reductase activity
NBH81_05640	COG0642	Histidine kinase
NBH81_05655	COG4221	oxidoreductase activity
NBH81_05665	COG1022	Amp-dependent synthetase and ligase
NBH81_05680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBH81_05695	COG3214	Protein conserved in bacteria
NBH81_05705	COG2195	Cleaves the N-terminal amino acid of tripeptides
NBH81_05710	COG0700	Nucleoside recognition
NBH81_05715	COG3366	ferrous iron transmembrane transporter activity
NBH81_05720	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NBH81_05725	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NBH81_05730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NBH81_05735	COG1053	succinate dehydrogenase
NBH81_05745	COG0584	glycerophosphoryl diester phosphodiesterase
NBH81_05750	COG1511	domain protein
NBH81_05750	COG3264	Mechanosensitive ion channel
NBH81_05760	COG0739	heme binding
NBH81_05770	COG0583	DNA-binding transcription factor activity
NBH81_05790	COG0583	DNA-binding transcription factor activity
NBH81_05795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NBH81_05825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NBH81_05830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NBH81_05840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NBH81_05845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NBH81_05855	COG0180	Tryptophanyl-tRNA synthetase
NBH81_05865	COG0512	Glutamine amidotransferase of anthranilate synthase
NBH81_05870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NBH81_05880	COG1012	belongs to the aldehyde dehydrogenase family
NBH81_05895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBH81_05905	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_05905	COG1013	pyruvate-flavodoxin oxidoreductase activity
NBH81_05905	COG0674	pyruvate-flavodoxin oxidoreductase activity
NBH81_05905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NBH81_05910	COG0366	Alpha amylase catalytic
NBH81_05930	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NBH81_05940	COG0471	metal ion transport
NBH81_05940	COG0490	domain, Protein
NBH81_05985	COG0012	GTP binding
NBH81_05990	COG0193	aminoacyl-tRNA hydrolase activity
NBH81_05995	COG0737	Belongs to the 5'-nucleotidase family
NBH81_06000	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NBH81_06010	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NBH81_06015	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NBH81_06020	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NBH81_06025	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NBH81_06030	COG2890	protein-(glutamine-N5) methyltransferase activity
NBH81_06040	COG2912	Transglutaminase-like superfamily
NBH81_06045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NBH81_06050	COG1301	dicarboxylic acid transport
NBH81_06065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NBH81_06080	COG1881	PFAM PEBP family protein
NBH81_06085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NBH81_06100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NBH81_06110	COG0583	DNA-binding transcription factor activity
NBH81_06115	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_06120	COG0616	signal peptide processing
NBH81_06125	COG2211	Major facilitator Superfamily
NBH81_06130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NBH81_06140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NBH81_06145	COG0826	peptidase U32
NBH81_06150	COG2203	Gaf domain
NBH81_06150	COG2199	diguanylate cyclase activity
NBH81_06150	COG2200	EAL domain
NBH81_06175	COG2197	response regulator
NBH81_06205	COG3724	N-succinylarginine dihydrolase activity
NBH81_06225	COG0840	transmembrane signaling receptor activity
NBH81_06235	COG2971	BadF BadG BcrA BcrD
NBH81_06245	COG4608	Belongs to the ABC transporter superfamily
NBH81_06250	COG0444	Belongs to the ABC transporter superfamily
NBH81_06255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBH81_06270	COG2205	protein histidine kinase activity
NBH81_06270	COG0784	Response regulator, receiver
NBH81_06300	COG3220	belongs to the UPF0276 family
NBH81_06335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NBH81_06340	COG1289	transmembrane transporter activity
NBH81_06345	COG0303	'Molybdopterin
NBH81_06350	COG0746	molybdenum cofactor guanylyltransferase activity
NBH81_06360	COG4662	Binding-protein-dependent transport system inner membrane component
NBH81_06370	COG2204	response regulator
NBH81_06375	COG3852	Histidine kinase
NBH81_06385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NBH81_06420	COG3383	formate dehydrogenase (NAD+) activity
NBH81_06420	COG3383	formate dehydrogenase (NAD+) activity
NBH81_06425	COG0437	4 iron, 4 sulfur cluster binding
NBH81_06445	COG0281	malic enzyme
NBH81_06465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_06500	COG1737	Transcriptional regulator
NBH81_06505	COG0469	pyruvate kinase activity
NBH81_06525	COG1677	Flagellar hook-basal body complex protein FliE
NBH81_06535	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NBH81_06585	COG1987	bacterial-type flagellum assembly
NBH81_06590	COG1684	flagellar biosynthetic protein fliR
NBH81_06600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NBH81_06625	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NBH81_06630	COG0643	Histidine kinase
NBH81_06630	COG0784	Response regulator, receiver
NBH81_06630	COG2198	Histidine kinase
NBH81_06640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NBH81_06645	COG1360	Flagellar Motor Protein
NBH81_06650	COG1192	Involved in chromosome partitioning
NBH81_06660	COG0835	chemotaxis
NBH81_06675	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NBH81_06680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NBH81_06685	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NBH81_06690	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NBH81_06695	COG1138	Cytochrome C-type biogenesis protein
NBH81_06700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NBH81_06705	COG4235	cytochrome complex assembly
NBH81_06705	COG3088	subunit of a heme lyase
NBH81_06725	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NBH81_06730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NBH81_06740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBH81_06745	COG1882	Formate acetyltransferase
NBH81_06755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBH81_06755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBH81_06760	COG0259	pyridoxamine-phosphate oxidase activity
NBH81_06785	COG2850	peptidyl-arginine hydroxylation
NBH81_06790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NBH81_06795	COG2915	High frequency lysogenization protein hflD homolog
NBH81_06800	COG0482	sulfurtransferase activity
NBH81_06810	COG1187	pseudouridine synthase activity
NBH81_06820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_06825	COG2271	Major facilitator Superfamily
NBH81_06830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_06830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_06830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_06845	COG4821	SIS domain
NBH81_06860	COG1609	Transcriptional regulator
NBH81_06865	COG1263	PTS System
NBH81_06865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_06870	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NBH81_06885	COG4792	protein secretion
NBH81_06890	COG4791	protein targeting
NBH81_06895	COG4794	Type iii secretion
NBH81_06900	COG4790	Type iii secretion
NBH81_06945	COG0457	Tetratricopeptide repeat
NBH81_06970	COG0457	Tetratricopeptide repeat
NBH81_07060	COG1317	bacterial-type flagellum organization
NBH81_07075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NBH81_07085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBH81_07090	COG1960	acyl-CoA dehydrogenase activity
NBH81_07100	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NBH81_07110	COG3383	formate dehydrogenase (NAD+) activity
NBH81_07120	COG0784	Response regulator, receiver
NBH81_07120	COG2205	protein histidine kinase activity
NBH81_07135	COG1401	restriction endodeoxyribonuclease activity
NBH81_07145	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NBH81_07150	COG0732	type I restriction modification DNA specificity domain
NBH81_07170	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NBH81_07200	COG0582	viral genome integration into host DNA
NBH81_07210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NBH81_07215	COG2867	negative regulation of translational initiation
NBH81_07220	COG2914	Belongs to the UPF0125 (RnfH) family
NBH81_07225	COG1473	amidohydrolase
NBH81_07230	COG1960	acyl-CoA dehydrogenase activity
NBH81_07235	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NBH81_07240	COG0121	glutamine amidotransferase
NBH81_07270	COG2197	response regulator
NBH81_07275	COG3850	Histidine kinase
NBH81_07280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NBH81_07285	COG0437	4 iron, 4 sulfur cluster binding
NBH81_07295	COG0243	molybdopterin cofactor binding
NBH81_07300	COG0437	4 iron, 4 sulfur cluster binding
NBH81_07305	COG0348	domain, Protein
NBH81_07315	COG3005	denitrification pathway
NBH81_07320	COG0521	Mo-molybdopterin cofactor biosynthetic process
NBH81_07325	COG0315	cyclic pyranopterin monophosphate synthase activity
NBH81_07330	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NBH81_07335	COG0314	molybdopterin synthase activity
NBH81_07350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NBH81_07355	COG2267	carboxylic ester hydrolase activity
NBH81_07370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NBH81_07375	COG0303	'Molybdopterin
NBH81_07380	COG0302	gtp cyclohydrolase
NBH81_07385	COG0840	transmembrane signaling receptor activity
NBH81_07390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NBH81_07400	COG0583	DNA-binding transcription factor activity
NBH81_07405	COG2353	YceI-like domain
NBH81_07430	COG2195	Cleaves the N-terminal amino acid of tripeptides
NBH81_07435	COG1166	arginine decarboxylase activity
NBH81_07455	COG0814	amino acid
NBH81_07460	COG0251	oxidation-reduction process
NBH81_07465	COG3681	Belongs to the UPF0597 family
NBH81_07470	COG2964	Protein conserved in bacteria
NBH81_07480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NBH81_07485	COG1288	antiporter activity
NBH81_07490	COG0436	Aminotransferase
NBH81_07500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NBH81_07505	COG0739	heme binding
NBH81_07505	COG0741	lytic transglycosylase activity
NBH81_07505	COG1196	nuclear chromosome segregation
NBH81_07520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBH81_07530	COG0788	formyltetrahydrofolate deformylase activity
NBH81_07535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NBH81_07555	COG0791	NLP P60 protein
NBH81_07560	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NBH81_07570	COG0471	metal ion transport
NBH81_07580	COG1388	LysM domain
NBH81_07580	COG1376	ErfK ybiS ycfS ynhG family protein
NBH81_07600	COG1263	PTS System
NBH81_07600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_07600	COG2190	(PTS) system
NBH81_07605	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NBH81_07625	COG3210	domain, Protein
NBH81_07630	COG2831	hemolysin activation secretion protein
NBH81_07660	COG2988	succinylglutamate desuccinylase activity
NBH81_07665	COG1388	LysM domain
NBH81_07665	COG0741	lytic transglycosylase activity
NBH81_07670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NBH81_07675	COG2226	methyltransferase
NBH81_07680	COG0328	RNA-DNA hybrid ribonuclease activity
NBH81_07685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NBH81_07695	COG0784	Response regulator, receiver
NBH81_07695	COG3437	response regulator, receiver
NBH81_07700	COG2375	cellular response to nickel ion
NBH81_07705	COG4771	TonB-dependent receptor
NBH81_07710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBH81_07715	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBH81_07720	COG1120	ATPase activity
NBH81_07725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NBH81_07735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBH81_07740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBH81_07765	COG0708	Exodeoxyribonuclease III
NBH81_07795	COG3132	Protein of unknown function, DUF480
NBH81_07800	COG3300	MHYT domain
NBH81_07800	COG5001	Diguanylate cyclase
NBH81_07810	COG2841	Protein conserved in bacteria
NBH81_07820	COG0534	Mate efflux family protein
NBH81_07850	COG1309	transcriptional regulator
NBH81_07885	COG3152	Membrane
NBH81_07900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_07915	COG2207	Transcriptional regulator
NBH81_07920	COG0538	isocitrate dehydrogenase activity
NBH81_07930	COG3048	D-serine ammonia-lyase activity
NBH81_07935	COG2610	gluconate transmembrane transporter activity
NBH81_07940	COG0583	DNA-binding transcription factor activity
NBH81_07950	COG0791	NLP P60 protein
NBH81_07955	COG0583	DNA-binding transcription factor activity
NBH81_07960	COG0450	alkyl hydroperoxide reductase
NBH81_07980	COG0500	methyltransferase
NBH81_07985	COG4106	trans-aconitate 2-methyltransferase activity
NBH81_07990	COG1801	Protein of unknown function DUF72
NBH81_08000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NBH81_08005	COG0217	transcriptional regulatory protein
NBH81_08010	COG1012	belongs to the aldehyde dehydrogenase family
NBH81_08010	COG1454	alcohol dehydrogenase
NBH81_08015	COG2095	MarC family integral membrane protein
NBH81_08025	COG0601	transmembrane transport
NBH81_08030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBH81_08045	COG0861	Integral membrane protein TerC family
NBH81_08050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBH81_08080	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NBH81_08090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NBH81_08095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NBH81_08100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NBH81_08105	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NBH81_08110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NBH81_08125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NBH81_08130	COG0505	Belongs to the CarA family
NBH81_08135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NBH81_08155	COG1126	abc transporter atp-binding protein
NBH81_08160	COG0765	amino acid transport
NBH81_08165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_08170	COG2203	Gaf domain
NBH81_08170	COG2199	diguanylate cyclase activity
NBH81_08175	COG2271	Major facilitator Superfamily
NBH81_08185	COG2197	response regulator
NBH81_08190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NBH81_08210	COG1785	Belongs to the alkaline phosphatase family
NBH81_08215	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NBH81_08220	COG0123	including yeast histone deacetylase and acetoin utilization protein
NBH81_08230	COG1199	ATP-dependent helicase activity
NBH81_08265	COG0346	lactoylglutathione lyase activity
NBH81_08270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NBH81_08275	COG4660	Part of a membrane complex involved in electron transport
NBH81_08280	COG4659	FMN binding
NBH81_08285	COG4658	electron transport chain
NBH81_08295	COG2878	Part of a membrane complex involved in electron transport
NBH81_08300	COG4657	Part of a membrane complex involved in electron transport
NBH81_08305	COG1403	HNH endonuclease
NBH81_08315	COG0346	lactoylglutathione lyase activity
NBH81_08330	COG1187	pseudouridine synthase activity
NBH81_08335	COG2807	transmembrane transport
NBH81_08345	COG0583	DNA-binding transcription factor activity
NBH81_08360	COG2979	Protein of unknown function (DUF533)
NBH81_08370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NBH81_08380	COG1294	oxidase, subunit
NBH81_08415	COG2249	NAD(P)H dehydrogenase (quinone) activity
NBH81_08420	COG2814	Major facilitator Superfamily
NBH81_08430	COG0656	L-ascorbic acid biosynthetic process
NBH81_08450	COG0583	DNA-binding transcription factor activity
NBH81_08460	COG0840	transmembrane signaling receptor activity
NBH81_08465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NBH81_08470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NBH81_08475	COG2271	Major facilitator Superfamily
NBH81_08480	COG1349	DNA-binding transcription factor activity
NBH81_08490	COG0584	glycerophosphoryl diester phosphodiesterase
NBH81_08495	COG4574	serine-type endopeptidase inhibitor activity
NBH81_08500	COG3085	chromosome segregation
NBH81_08505	COG0583	DNA-binding transcription factor activity
NBH81_08515	COG1448	Aminotransferase
NBH81_08530	COG2333	competence protein COMEC
NBH81_08530	COG0658	competence protein
NBH81_08540	COG1663	tetraacyldisaccharide 4'-kinase activity
NBH81_08545	COG2835	tetraacyldisaccharide 4'-kinase activity
NBH81_08550	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NBH81_08555	COG2197	response regulator
NBH81_08560	COG0322	excinuclease ABC activity
NBH81_08595	COG1605	Chorismate mutase
NBH81_08595	COG0287	Prephenate dehydrogenase
NBH81_08600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NBH81_08610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NBH81_08615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NBH81_08650	COG0537	adenosine 5'-monophosphoramidase activity
NBH81_08665	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NBH81_08680	COG1301	dicarboxylic acid transport
NBH81_08685	COG0840	transmembrane signaling receptor activity
NBH81_08695	COG2354	Protein conserved in bacteria
NBH81_08705	COG2233	PERMEase
NBH81_08710	COG3150	esterase
NBH81_08715	COG1252	NADH dehydrogenase
NBH81_08725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBH81_08730	COG3300	MHYT domain
NBH81_08730	COG5001	Diguanylate cyclase
NBH81_08735	COG0446	pyridine nucleotide-disulphide oxidoreductase
NBH81_08745	COG2373	Large extracellular alpha-helical protein
NBH81_08750	COG4953	penicillin-binding protein 1C
NBH81_08760	COG0301	tRNA thio-modification
NBH81_08760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBH81_08780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NBH81_08825	COG2089	acid synthase
NBH81_08840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NBH81_08845	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NBH81_08855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NBH81_08860	COG1086	Polysaccharide biosynthesis protein
NBH81_08875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NBH81_08890	COG0483	inositol monophosphate 1-phosphatase activity
NBH81_08900	COG0625	glutathione transferase activity
NBH81_08905	COG2814	Major facilitator Superfamily
NBH81_08925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBH81_08930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NBH81_08935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NBH81_08940	COG0509	glycine decarboxylation via glycine cleavage system
NBH81_08945	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NBH81_08945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NBH81_08970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NBH81_09010	COG5642	Protein of unknown function (DUF2384)
NBH81_09025	COG0840	transmembrane signaling receptor activity
NBH81_09055	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NBH81_09060	COG0574	Belongs to the PEP-utilizing enzyme family
NBH81_09060	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NBH81_09075	COG1464	Belongs to the NlpA lipoprotein family
NBH81_09080	COG3083	sulfuric ester hydrolase activity
NBH81_09085	COG3082	Protein of unknown function (DUF1414)
NBH81_09090	COG3081	Nucleoid-associated protein
NBH81_09100	COG1175	transmembrane transport
NBH81_09105	COG3833	ABC-type maltose transport systems, permease component
NBH81_09110	COG3842	ATPase activity
NBH81_09140	COG4783	chaperone-mediated protein folding
NBH81_09150	COG1393	Belongs to the ArsC family
NBH81_09160	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
NBH81_09165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_09170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NBH81_09175	COG2431	L-lysine efflux transmembrane transporter activity
NBH81_09185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_09195	COG4160	amino acid transport
NBH81_09200	COG0564	pseudouridine synthase activity
NBH81_09215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NBH81_09225	COG0625	glutathione transferase activity
NBH81_09255	COG1360	Flagellar Motor Protein
NBH81_09260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NBH81_09275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NBH81_09285	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NBH81_09290	COG4597	amino acid ABC transporter
NBH81_09295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_09300	COG0765	amino acid transport
NBH81_09305	COG1126	abc transporter atp-binding protein
NBH81_09315	COG0724	RNA recognition motif
NBH81_09320	COG4989	oxidoreductase activity
NBH81_09345	COG3437	response regulator, receiver
NBH81_09350	COG0583	DNA-binding transcription factor activity
NBH81_09355	COG3300	MHYT domain
NBH81_09355	COG5001	Diguanylate cyclase
NBH81_09360	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NBH81_09380	COG2814	Major facilitator Superfamily
NBH81_09395	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NBH81_09400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NBH81_09405	COG0539	negative regulation of cytoplasmic translation
NBH81_09410	COG0776	regulation of translation
NBH81_09420	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NBH81_09440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NBH81_09445	COG0602	queuosine metabolic process
NBH81_09450	COG3530	Putative quorum-sensing-regulated virulence factor
NBH81_09455	COG2096	Adenosyltransferase
NBH81_09460	COG2916	Histone family protein nucleoid-structuring protein H-NS
NBH81_09465	COG1757	Na H antiporter
NBH81_09470	COG1435	thymidine kinase activity
NBH81_09530	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NBH81_09535	COG0326	Molecular chaperone. Has ATPase activity
NBH81_09540	COG4172	Belongs to the ABC transporter superfamily
NBH81_09545	COG4172	Belongs to the ABC transporter superfamily
NBH81_09555	COG4168	peptide transport system, permease
NBH81_09565	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NBH81_09570	COG1842	Phage shock protein A
NBH81_09585	COG3106	COG3106 Predicted ATPase
NBH81_09590	COG3768	UPF0283 membrane protein
NBH81_09595	COG0583	DNA-binding transcription factor activity
NBH81_09600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NBH81_09605	COG3842	ATPase activity
NBH81_09610	COG1176	ABC-type spermidine putrescine transport system, permease component I
NBH81_09615	COG1177	transmembrane transport
NBH81_09620	COG1012	belongs to the aldehyde dehydrogenase family
NBH81_09645	COG2199	diguanylate cyclase activity
NBH81_09650	COG2885	chlorophyll binding
NBH81_09655	COG0861	Integral membrane protein TerC family
NBH81_09685	COG2910	NAD(P)H-binding
NBH81_09690	COG0583	DNA-binding transcription factor activity
NBH81_09695	COG0583	DNA-binding transcription factor activity
NBH81_09700	COG2271	Major facilitator Superfamily
NBH81_09710	COG1335	isochorismatase
NBH81_09720	COG0583	DNA-binding transcription factor activity
NBH81_09725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NBH81_09735	COG0583	DNA-binding transcription factor activity
NBH81_09740	COG2723	6-phospho-beta-galactosidase activity
NBH81_09745	COG1944	ATP diphosphatase activity
NBH81_09750	COG2116	formate transmembrane transporter activity
NBH81_09755	COG1882	Formate acetyltransferase
NBH81_09760	COG2983	Belongs to the UPF0260 family
NBH81_09775	COG0058	SHG alpha-glucan phosphorylase activity
NBH81_09825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NBH81_09830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NBH81_09835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NBH81_09850	COG0513	Belongs to the DEAD box helicase family
NBH81_09855	COG0386	Belongs to the glutathione peroxidase family
NBH81_09865	COG1181	Belongs to the D-alanine--D-alanine ligase family
NBH81_09870	COG0383	alpha-mannosidase activity
NBH81_09875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_09875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_09875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_09880	COG2188	Transcriptional regulator
NBH81_09885	COG1570	exodeoxyribonuclease VII activity
NBH81_09890	COG3038	cytochrome b561
NBH81_09895	COG0517	IMP dehydrogenase activity
NBH81_09895	COG0516	GMP reductase activity
NBH81_09900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NBH81_09900	COG0519	Catalyzes the synthesis of GMP from XMP
NBH81_09935	COG0417	DNA replication proofreading
NBH81_09950	COG1451	nucleotide metabolic process
NBH81_09965	COG1025	Belongs to the peptidase M16 family
NBH81_09970	COG2062	phosphohistidine phosphatase, SixA
NBH81_09980	COG0697	spore germination
NBH81_10000	COG3069	C4-dicarboxylate transmembrane transporter activity
NBH81_10015	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NBH81_10015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBH81_10020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NBH81_10025	COG2985	domain, Protein
NBH81_10025	COG0569	domain protein
NBH81_10040	COG0556	nucleotide-excision repair
NBH81_10050	COG0586	Pfam SNARE associated Golgi protein
NBH81_10055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NBH81_10060	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NBH81_10075	COG4681	YaeQ
NBH81_10090	COG3829	transcription factor binding
NBH81_10135	COG0307	riboflavin synthase, alpha
NBH81_10145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBH81_10150	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NBH81_10155	COG0697	spore germination
NBH81_10160	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NBH81_10205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NBH81_10210	COG3099	Belongs to the UPF0263 family
NBH81_10215	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NBH81_10220	COG2894	cell division
NBH81_10225	COG0850	regulation of cytokinetic process
NBH81_10230	COG3100	YcgL domain-containing protein
NBH81_10235	COG1760	l-serine dehydratase
NBH81_10240	COG1760	l-serine dehydratase
NBH81_10245	COG3123	guanosine phosphorylase activity
NBH81_10255	COG0205	6-phosphofructokinase activity
NBH81_10265	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NBH81_10270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NBH81_10280	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NBH81_10285	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NBH81_10290	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NBH81_10310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NBH81_10315	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NBH81_10315	COG0617	tRNA 3'-terminal CCA addition
NBH81_10315	COG0517	IMP dehydrogenase activity
NBH81_10320	COG1643	Atp-dependent helicase
NBH81_10330	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NBH81_10345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NBH81_10350	COG2067	long-chain fatty acid transport protein
NBH81_10365	COG1595	DNA-templated transcription, initiation
NBH81_10375	COG2304	oxidoreductase activity
NBH81_10395	COG0714	Associated with various cellular activities
NBH81_10400	COG0183	Belongs to the thiolase family
NBH81_10405	COG1024	Enoyl-CoA hydratase
NBH81_10405	COG1250	3-hydroxyacyl-CoA dehydrogenase
NBH81_10410	COG2719	SpoVR family
NBH81_10415	COG2718	Belongs to the UPF0229 family
NBH81_10420	COG2766	serine protein kinase
NBH81_10425	COG0514	ATP-dependent DNA helicase (RecQ)
NBH81_10430	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NBH81_10435	COG0814	amino acid
NBH81_10440	COG0494	nUDIX hydrolase
NBH81_10455	COG2824	Alkylphosphonate utilization operon protein PhnA
NBH81_10470	COG0406	alpha-ribazole phosphatase activity
NBH81_10475	COG3706	GGDEF domain
NBH81_10480	COG2840	Smr protein MutS2
NBH81_10485	COG2890	protein-(glutamine-N5) methyltransferase activity
NBH81_10490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NBH81_10500	COG0513	Belongs to the DEAD box helicase family
NBH81_10510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBH81_10510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBH81_10515	COG0489	protein tyrosine kinase activity
NBH81_10520	COG0572	uridine kinase
NBH81_10525	COG0717	Belongs to the dCTP deaminase family
NBH81_10530	COG0306	phosphate transporter
NBH81_10545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NBH81_10550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NBH81_10555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NBH81_10565	COG0549	Belongs to the carbamate kinase family
NBH81_10570	COG0697	spore germination
NBH81_10580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NBH81_10580	COG3608	succinylglutamate desuccinylase aspartoacylase
NBH81_10585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NBH81_10590	COG2068	MobA-Related Protein
NBH81_10600	COG0493	'glutamate synthase
NBH81_10600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NBH81_10605	COG0402	S-adenosylhomocysteine deaminase activity
NBH81_10610	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NBH81_10615	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NBH81_10615	COG2080	2 iron, 2 sulfur cluster binding
NBH81_10620	COG2233	PERMEase
NBH81_10625	COG0402	S-adenosylhomocysteine deaminase activity
NBH81_10630	COG2252	PERMEase
NBH81_10635	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NBH81_10640	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NBH81_10645	COG2080	2 iron, 2 sulfur cluster binding
NBH81_10650	COG3134	Outer membrane lipoprotein
NBH81_10660	COG1288	antiporter activity
NBH81_10665	COG0318	PFAM AMP-dependent synthetase and ligase
NBH81_10670	COG2199	diguanylate cyclase activity
NBH81_10685	COG0107	imidazoleglycerol-phosphate synthase activity
NBH81_10690	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NBH81_10695	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NBH81_10700	COG0131	Imidazoleglycerol-phosphate dehydratase
NBH81_10700	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NBH81_10705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NBH81_10710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NBH81_10715	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NBH81_10725	COG1199	ATP-dependent helicase activity
NBH81_10730	COG1214	PFAM Peptidase M22, glycoprotease
NBH81_10740	COG2267	carboxylic ester hydrolase activity
NBH81_10745	COG0318	PFAM AMP-dependent synthetase and ligase
NBH81_10755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NBH81_10760	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NBH81_10765	COG0709	Synthesizes selenophosphate from selenide and ATP
NBH81_10775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NBH81_10780	COG0840	transmembrane signaling receptor activity
NBH81_10785	COG1254	Belongs to the acylphosphatase family
NBH81_10795	COG3385	transposase activity
NBH81_10800	COG1530	ribonuclease E activity
NBH81_10815	COG0424	maF-like protein
NBH81_10820	COG1399	metal-binding, possibly nucleic acid-binding protein
NBH81_10825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NBH81_10830	COG0416	fatty acid biosynthetic process
NBH81_10835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBH81_10845	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_10850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NBH81_10855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NBH81_10860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NBH81_10865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NBH81_10870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NBH81_10875	COG0470	DNA polymerase III
NBH81_10880	COG0084	hydrolase, TatD family'
NBH81_10895	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NBH81_10895	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBH81_10900	COG3008	intermembrane lipid transfer
NBH81_10905	COG2995	paraquat-inducible protein a
NBH81_10915	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NBH81_10920	COG0372	Belongs to the citrate synthase family
NBH81_10965	COG4221	oxidoreductase activity
NBH81_10970	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NBH81_10975	COG3141	response to X-ray
NBH81_10995	COG2336	PFAM SpoVT AbrB
NBH81_11050	COG1067	ATP-dependent peptidase activity
NBH81_11055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NBH81_11065	COG0488	(ABC) transporter
NBH81_11075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NBH81_11075	COG0116	Belongs to the methyltransferase superfamily
NBH81_11080	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NBH81_11085	COG0254	rRNA binding
NBH81_11100	COG0167	dihydroorotate dehydrogenase activity
NBH81_11105	COG2902	Dehydrogenase
NBH81_11115	COG0308	aminopeptidase N
NBH81_11125	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NBH81_11130	COG1956	GAF domain-containing protein
NBH81_11140	COG3278	Belongs to the heme-copper respiratory oxidase family
NBH81_11155	COG2010	Cytochrome c
NBH81_11165	COG2217	Heavy metal translocating P-type atpase
NBH81_11180	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NBH81_11185	COG0589	response to stress
NBH81_11190	COG0037	tRNA processing
NBH81_11215	COG1177	transmembrane transport
NBH81_11230	COG0625	glutathione transferase activity
NBH81_11235	COG1869	D-ribose catabolic process
NBH81_11240	COG1129	ABC transporter
NBH81_11245	COG1172	Belongs to the binding-protein-dependent transport system permease family
NBH81_11250	COG1879	ABC-type sugar transport system periplasmic component
NBH81_11255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBH81_11260	COG1609	Transcriptional regulator
NBH81_11265	COG3300	MHYT domain
NBH81_11265	COG5001	Diguanylate cyclase
NBH81_11290	COG0784	Response regulator, receiver
NBH81_11290	COG2205	protein histidine kinase activity
NBH81_11295	COG0776	regulation of translation
NBH81_11300	COG0072	phenylalanine-tRNA ligase activity
NBH81_11300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBH81_11305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NBH81_11310	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NBH81_11315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NBH81_11320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NBH81_11325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NBH81_11345	COG0366	Alpha amylase catalytic
NBH81_11355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NBH81_11365	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBH81_11370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NBH81_11375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NBH81_11380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NBH81_11385	COG3313	Fe-S protein
NBH81_11390	COG2942	2-epimerase
NBH81_11395	COG3716	PTS system mannose fructose sorbose family IID component
NBH81_11400	COG3715	PTS system
NBH81_11405	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_11405	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_11420	COG1609	Transcriptional regulator
NBH81_11425	COG2140	Oxalate decarboxylase
NBH81_11430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_11430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NBH81_11430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NBH81_11435	COG1105	Belongs to the carbohydrate kinase PfkB family
NBH81_11440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_11440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_11445	COG1609	Transcriptional regulator
NBH81_11450	COG0814	amino acid
NBH81_11500	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBH81_11505	COG3457	Alanine racemase
NBH81_11520	COG1735	metal-dependent hydrolase with the TIM-barrel fold
NBH81_11530	COG2188	Transcriptional regulator
NBH81_11565	COG2925	Exonuclease
NBH81_11575	COG3345	alpha-galactosidase
NBH81_11580	COG1380	Effector of murein hydrolase LrgA
NBH81_11585	COG1346	cytolysis
NBH81_11590	COG0295	cytidine deaminase activity
NBH81_11595	COG3033	Beta-eliminating lyase
NBH81_11605	COG3046	protein related to deoxyribodipyrimidine photolyase
NBH81_11610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBH81_11615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBH81_11640	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NBH81_11655	COG3158	transport of potassium into the cell
NBH81_11660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NBH81_11665	COG0651	ATP synthesis coupled electron transport
NBH81_11670	COG0650	Formate hydrogenlyase subunit 4
NBH81_11675	COG3261	NADH dehydrogenase
NBH81_11675	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NBH81_11680	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_11685	COG3260	NADH ubiquinone oxidoreductase 20
NBH81_11695	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NBH81_11705	COG1921	L-seryl-tRNASec selenium transferase activity
NBH81_11715	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NBH81_11720	COG0298	carbon dioxide binding
NBH81_11730	COG0309	Hydrogenase expression formation protein (HypE)
NBH81_11735	COG0375	protein maturation
NBH81_11745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NBH81_11750	COG3842	ATPase activity
NBH81_11755	COG0444	Belongs to the ABC transporter superfamily
NBH81_11760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NBH81_11765	COG0601	transmembrane transport
NBH81_11775	COG1773	rubredoxin
NBH81_11780	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NBH81_11785	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NBH81_11790	COG5557	Pfam Polysulphide reductase, NrfD
NBH81_11795	COG0437	4 iron, 4 sulfur cluster binding
NBH81_11800	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NBH81_11815	COG3437	response regulator, receiver
NBH81_11820	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NBH81_11825	COG2203	Gaf domain
NBH81_11825	COG3706	GGDEF domain
NBH81_11825	COG4251	negative regulation of phosphorylation
NBH81_11825	COG5001	Diguanylate cyclase
NBH81_11830	COG0438	transferase activity, transferring glycosyl groups
NBH81_11835	COG0297	glycogen (starch) synthase activity
NBH81_11855	COG0438	transferase activity, transferring glycosyl groups
NBH81_11900	COG0438	transferase activity, transferring glycosyl groups
NBH81_11905	COG1215	transferase activity, transferring glycosyl groups
NBH81_11910	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NBH81_11950	COG0784	Response regulator, receiver
NBH81_11950	COG2205	protein histidine kinase activity
NBH81_11960	COG0730	response to heat
NBH81_11970	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_11980	COG1024	Enoyl-CoA hydratase
NBH81_11985	COG1024	Enoyl-CoA hydratase
NBH81_11990	COG1960	acyl-CoA dehydrogenase activity
NBH81_11995	COG1960	acyl-CoA dehydrogenase activity
NBH81_12000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NBH81_12005	COG1024	Enoyl-CoA hydratase
NBH81_12035	COG1584	GPR1 FUN34 yaaH family protein
NBH81_12050	COG1115	amino acid carrier protein
NBH81_12055	COG1024	Enoyl-CoA hydratase
NBH81_12070	COG3162	membrane
NBH81_12075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NBH81_12080	COG0488	(ABC) transporter
NBH81_12085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBH81_12090	COG0776	regulation of translation
NBH81_12095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NBH81_12100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NBH81_12105	COG0740	serine-type endopeptidase activity
NBH81_12110	COG0544	peptidyl-prolyl cis-trans isomerase activity
NBH81_12120	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NBH81_12125	COG4591	ABC-type transport system involved in lipoprotein release permease component
NBH81_12130	COG1136	(ABC) transporter
NBH81_12135	COG4591	ABC-type transport system involved in lipoprotein release permease component
NBH81_12145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NBH81_12150	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NBH81_12170	COG1560	Kdo2-lipid A biosynthetic process
NBH81_12175	COG1560	Kdo2-lipid A biosynthetic process
NBH81_12190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NBH81_12195	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NBH81_12205	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NBH81_12210	COG2832	Protein of unknown function (DUF454)
NBH81_12215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NBH81_12230	COG1011	Hydrolase
NBH81_12235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NBH81_12285	COG3593	DNA synthesis involved in DNA repair
NBH81_12300	COG0583	DNA-binding transcription factor activity
NBH81_12305	COG0730	response to heat
NBH81_12310	COG3148	PFAM DTW domain containing protein
NBH81_12315	COG1846	Transcriptional regulator
NBH81_12315	COG1940	carbohydrate kinase activity
NBH81_12320	COG0840	transmembrane signaling receptor activity
NBH81_12325	COG3012	SEC-C Motif Domain Protein
NBH81_12330	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NBH81_12335	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NBH81_12340	COG0247	lactate metabolic process
NBH81_12355	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NBH81_12360	COG0437	4 iron, 4 sulfur cluster binding
NBH81_12365	COG3301	Polysulphide reductase, NrfD
NBH81_12370	COG1138	Cytochrome C-type biogenesis protein
NBH81_12380	COG4235	cytochrome complex assembly
NBH81_12380	COG3088	subunit of a heme lyase
NBH81_12395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NBH81_12405	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NBH81_12415	COG1840	ABC-type Fe3 transport system, periplasmic component
NBH81_12420	COG3842	ATPase activity
NBH81_12430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBH81_12445	COG0045	succinate-CoA ligase (ADP-forming) activity
NBH81_12450	COG0508	dehydrogenase complex catalyzes the overall conversion of
NBH81_12455	COG0567	Dehydrogenase, E1 component
NBH81_12465	COG1053	succinate dehydrogenase
NBH81_12470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NBH81_12475	COG2009	succinate dehydrogenase
NBH81_12515	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NBH81_12530	COG2501	S4 domain
NBH81_12540	COG1132	(ABC) transporter
NBH81_12545	COG1132	(ABC) transporter
NBH81_12555	COG3118	belongs to the thioredoxin family
NBH81_12560	COG0471	metal ion transport
NBH81_12590	COG5001	Diguanylate cyclase
NBH81_12590	COG3300	MHYT domain
NBH81_12605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBH81_12615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NBH81_12620	COG0563	adenylate kinase activity
NBH81_12630	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NBH81_12635	COG1286	toxin biosynthetic process
NBH81_12645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NBH81_12650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NBH81_12655	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NBH81_12660	COG1674	ftsk spoiiie
NBH81_12660	COG0531	amino acid
NBH81_12670	COG0686	Belongs to the AlaDH PNT family
NBH81_12675	COG0492	ferredoxin-NADP+ reductase activity
NBH81_12680	COG3706	GGDEF domain
NBH81_12685	COG3134	Outer membrane lipoprotein
NBH81_12690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NBH81_12695	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NBH81_12700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NBH81_12705	COG0542	response to heat
NBH81_12710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NBH81_12715	COG1278	Cold shock
NBH81_12720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NBH81_12740	COG0745	RESPONSE REGULATOR receiver
NBH81_12745	COG2205	protein histidine kinase activity
NBH81_12755	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NBH81_12755	COG0392	lysyltransferase activity
NBH81_12770	COG0659	secondary active sulfate transmembrane transporter activity
NBH81_12825	COG0582	viral genome integration into host DNA
NBH81_12840	COG2314	TM2 domain
NBH81_12870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NBH81_12875	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NBH81_12935	COG0672	)-iron permease
NBH81_12960	COG2814	Major facilitator Superfamily
NBH81_12975	COG1136	(ABC) transporter
NBH81_12980	COG0577	efflux transmembrane transporter activity
NBH81_12990	COG1285	pathogenesis
NBH81_13000	COG0596	Alpha beta hydrolase
NBH81_13020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NBH81_13025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NBH81_13025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NBH81_13030	COG0527	aspartate kinase activity
NBH81_13040	COG1368	sulfuric ester hydrolase activity
NBH81_13045	COG1619	proteins homologs of microcin C7 resistance protein MccF
NBH81_13050	COG4667	esterase of the alpha-beta hydrolase superfamily
NBH81_13070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NBH81_13070	COG1648	precorrin-2 dehydrogenase activity
NBH81_13080	COG0393	Putative heavy-metal-binding
NBH81_13085	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NBH81_13090	COG0285	dihydrofolate synthase activity
NBH81_13095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NBH81_13100	COG0101	tRNA pseudouridine synthase activity
NBH81_13110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NBH81_13115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NBH81_13120	COG0671	phosphoesterase, PA-phosphatase related
NBH81_13125	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NBH81_13130	COG2056	Na+-H+ antiporter family
NBH81_13155	COG0513	Belongs to the DEAD box helicase family
NBH81_13160	COG2050	protein possibly involved in aromatic compounds catabolism
NBH81_13170	COG0277	FAD linked oxidase domain protein
NBH81_13170	COG0247	lactate metabolic process
NBH81_13180	COG1253	flavin adenine dinucleotide binding
NBH81_13185	COG1902	pentaerythritol trinitrate reductase activity
NBH81_13200	COG0647	UMP catabolic process
NBH81_13205	COG4651	solute:proton antiporter activity
NBH81_13205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NBH81_13215	COG0367	asparagine synthase
NBH81_13230	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_13235	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_13240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_13240	COG0649	NAD binding
NBH81_13255	COG1034	ATP synthesis coupled electron transport
NBH81_13260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NBH81_13265	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_13270	COG0839	Belongs to the complex I subunit 6 family
NBH81_13275	COG0713	ATP synthesis coupled electron transport
NBH81_13285	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NBH81_13290	COG1007	ATP synthesis coupled electron transport
NBH81_13305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NBH81_13305	COG0047	phosphoribosylformylglycinamidine synthase activity
NBH81_13310	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NBH81_13315	COG1645	bacterial-type flagellum-dependent swarming motility
NBH81_13320	COG1160	GTP binding
NBH81_13325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NBH81_13330	COG2976	Protein conserved in bacteria
NBH81_13335	COG0124	histidyl-tRNA synthetase
NBH81_13355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NBH81_13360	COG0105	UTP biosynthetic process
NBH81_13375	COG0633	Ferredoxin
NBH81_13380	COG0443	Heat shock 70 kDa protein
NBH81_13385	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NBH81_13395	COG0822	iron-sulfur transferase activity
NBH81_13400	COG1104	cysteine desulfurase activity
NBH81_13420	COG3154	lipid carrier protein
NBH81_13425	COG0826	peptidase U32
NBH81_13430	COG0826	peptidase U32
NBH81_13445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NBH81_13450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NBH81_13455	COG1862	Preprotein translocase
NBH81_13460	COG0343	queuine tRNA-ribosyltransferase activity
NBH81_13465	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NBH81_13470	COG0517	IMP dehydrogenase activity
NBH81_13480	COG3634	alkyl hydroperoxide reductase activity
NBH81_13525	COG1242	4 iron, 4 sulfur cluster binding
NBH81_13530	COG0070	glutamate synthase
NBH81_13530	COG0067	glutamate synthase
NBH81_13530	COG0069	glutamate synthase activity
NBH81_13535	COG0493	'glutamate synthase
NBH81_13540	COG1126	abc transporter atp-binding protein
NBH81_13545	COG0765	amino acid transport
NBH81_13550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_13565	COG0513	Belongs to the DEAD box helicase family
NBH81_13590	COG0023	Translation Initiation Factor
NBH81_13595	COG2119	membrane
NBH81_13640	COG0215	cysteine-tRNA ligase activity
NBH81_13645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NBH81_13655	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NBH81_13665	COG2261	transglycosylase associated protein
NBH81_13670	COG0642	Histidine kinase
NBH81_13710	COG0531	amino acid
NBH81_13715	COG1410	methionine synthase
NBH81_13715	COG0646	methionine synthase
NBH81_13725	COG1253	flavin adenine dinucleotide binding
NBH81_13730	COG0704	Plays a role in the regulation of phosphate uptake
NBH81_13735	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NBH81_13740	COG0581	inorganic phosphate transmembrane transporter activity
NBH81_13745	COG0573	inorganic phosphate transmembrane transporter activity
NBH81_13750	COG0590	tRNA wobble adenosine to inosine editing
NBH81_13765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NBH81_13785	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NBH81_13790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NBH81_13795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NBH81_13800	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NBH81_13825	COG2716	regulation of RNA biosynthetic process
NBH81_13830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NBH81_13840	COG2239	Acts as a magnesium transporter
NBH81_13845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NBH81_13855	COG1705	Flagellar rod assembly protein muramidase FlgJ
NBH81_13855	COG3951	Flagellar rod assembly protein muramidase FlgJ
NBH81_13860	COG1706	bacterial-type flagellum-dependent cell motility
NBH81_13865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NBH81_13875	COG4787	bacterial-type flagellum-dependent cell motility
NBH81_13885	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NBH81_13895	COG1815	bacterial-type flagellum-dependent cell motility
NBH81_13900	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NBH81_13905	COG0784	Response regulator, receiver
NBH81_13905	COG0835	chemotaxis
NBH81_13910	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
NBH81_13925	COG0622	Phosphoesterase
NBH81_13930	COG4166	transmembrane transport
NBH81_13945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NBH81_13955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NBH81_13960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NBH81_13965	COG1882	Formate acetyltransferase
NBH81_13970	COG1349	DNA-binding transcription factor activity
NBH81_13975	COG4166	transmembrane transport
NBH81_14000	COG1278	Cold shock
NBH81_14025	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NBH81_14025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NBH81_14030	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_14035	COG3433	isochorismatase activity
NBH81_14035	COG1535	isochorismatase
NBH81_14040	COG1021	2,3-dihydroxybenzoate-AMP ligase
NBH81_14045	COG1169	isochorismate synthase
NBH81_14050	COG4771	TonB-dependent receptor
NBH81_14055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NBH81_14065	COG0741	lytic transglycosylase activity
NBH81_14075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NBH81_14095	COG2911	Protein conserved in bacteria
NBH81_14100	COG0729	surface antigen
NBH81_14110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBH81_14120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NBH81_14130	COG4134	Bacterial extracellular solute-binding protein
NBH81_14140	COG4136	ATPase activity
NBH81_14145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NBH81_14150	COG2951	lytic endotransglycosylase activity
NBH81_14155	COG1846	Transcriptional regulator
NBH81_14165	COG0033	Phosphoglucomutase
NBH81_14170	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NBH81_14175	COG0596	Alpha beta hydrolase
NBH81_14190	COG0716	FMN binding
NBH81_14200	COG0735	belongs to the Fur family
NBH81_14205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBH81_14215	COG1263	PTS System
NBH81_14215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_14215	COG2190	(PTS) system
NBH81_14220	COG0363	glucosamine-6-phosphate deaminase activity
NBH81_14225	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NBH81_14230	COG1940	carbohydrate kinase activity
NBH81_14230	COG1846	Transcriptional regulator
NBH81_14235	COG2194	sulfuric ester hydrolase activity
NBH81_14240	COG2199	diguanylate cyclase activity
NBH81_14240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NBH81_14245	COG3275	phosphorelay sensor kinase activity
NBH81_14250	COG3279	Response regulator of the LytR AlgR family
NBH81_14255	COG1966	Carbon starvation protein
NBH81_14265	COG1566	PFAM secretion protein HlyD family protein
NBH81_14270	COG1061	Type III restriction enzyme res subunit
NBH81_14275	COG2027	D-alanyl-D-alanine carboxypeptidase
NBH81_14280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NBH81_14285	COG3021	interspecies interaction between organisms
NBH81_14295	COG1607	acyl-coa hydrolase
NBH81_14300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NBH81_14310	COG1013	pyruvate-flavodoxin oxidoreductase activity
NBH81_14310	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NBH81_14310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NBH81_14310	COG0674	pyruvate-flavodoxin oxidoreductase activity
NBH81_14325	COG0633	Ferredoxin
NBH81_14325	COG3217	Mosc domain protein beta barrel domain protein
NBH81_14325	COG0633	Ferredoxin
NBH81_14325	COG3217	Mosc domain protein beta barrel domain protein
NBH81_14335	COG0501	Belongs to the peptidase M48B family
NBH81_14340	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NBH81_14345	COG1073	alpha beta
NBH81_14345	COG2226	methyltransferase
NBH81_14350	COG0156	8-amino-7-oxononanoate synthase activity
NBH81_14355	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NBH81_14360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NBH81_14375	COG0017	Asparaginyl-tRNA synthetase
NBH81_14385	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NBH81_14395	COG1473	amidohydrolase
NBH81_14400	COG3069	C4-dicarboxylate transmembrane transporter activity
NBH81_14410	COG1393	Belongs to the ArsC family
NBH81_14415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NBH81_14420	COG1876	peptidase activity
NBH81_14430	COG3263	regulation of cellular component size
NBH81_14445	COG1280	lysine exporter protein (LysE YggA)
NBH81_14475	COG0564	pseudouridine synthase activity
NBH81_14485	COG1454	alcohol dehydrogenase
NBH81_14490	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NBH81_14495	COG0702	epimerase
NBH81_14505	COG0095	Lipoate-protein ligase
NBH81_14515	COG0577	efflux transmembrane transporter activity
NBH81_14515	COG1136	(ABC) transporter
NBH81_14520	COG1136	(ABC) transporter
NBH81_14520	COG0577	efflux transmembrane transporter activity
NBH81_14525	COG0577	efflux transmembrane transporter activity
NBH81_14525	COG1136	(ABC) transporter
NBH81_14530	COG1566	PFAM secretion protein HlyD family protein
NBH81_14570	COG1285	pathogenesis
NBH81_14600	COG0484	heat shock protein binding
NBH81_14605	COG0443	Heat shock 70 kDa protein
NBH81_14610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NBH81_14615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NBH81_14620	COG0497	DNA recombination
NBH81_14625	COG1227	inorganic diphosphatase activity
NBH81_14630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBH81_14635	COG0577	efflux transmembrane transporter activity
NBH81_14635	COG1136	(ABC) transporter
NBH81_14660	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
NBH81_14675	COG1091	dTDP-4-dehydrorhamnose reductase activity
NBH81_14690	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NBH81_14700	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NBH81_14735	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBH81_14760	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NBH81_14765	COG0673	inositol 2-dehydrogenase activity
NBH81_14770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBH81_14775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBH81_14780	COG1309	transcriptional regulator
NBH81_14795	COG1342	Belongs to the UPF0251 family
NBH81_14815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NBH81_14830	COG0488	(ABC) transporter
NBH81_14835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NBH81_14840	COG0083	homoserine kinase activity
NBH81_14850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NBH81_14855	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NBH81_14860	COG1946	Acyl-CoA thioesterase
NBH81_14875	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NBH81_14885	COG0009	L-threonylcarbamoyladenylate synthase
NBH81_14895	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NBH81_14900	COG0512	Glutamine amidotransferase of anthranilate synthase
NBH81_14900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NBH81_14905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NBH81_14910	COG0135	phosphoribosylanthranilate isomerase activity
NBH81_14910	COG0134	indole-3-glycerol-phosphate synthase activity
NBH81_14915	COG0133	tryptophan synthase activity
NBH81_14920	COG0159	tryptophan synthase activity
NBH81_14940	COG1988	membrane-bound metal-dependent
NBH81_14960	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NBH81_14970	COG0798	PFAM Bile acid sodium symporter
NBH81_15000	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NBH81_15010	COG0745	RESPONSE REGULATOR receiver
NBH81_15025	COG4988	ABC transporter
NBH81_15030	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NBH81_15050	COG1720	tRNA m6t6A37 methyltransferase activity
NBH81_15055	COG3038	cytochrome b561
NBH81_15075	COG2862	Uncharacterized protein family, UPF0114
NBH81_15090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBH81_15095	COG1917	Cupin 2, conserved barrel domain protein
NBH81_15095	COG1396	sequence-specific DNA binding
NBH81_15110	COG0531	amino acid
NBH81_15120	COG0531	amino acid
NBH81_15125	COG1283	sodium-dependent phosphate transmembrane transporter activity
NBH81_15135	COG0405	Gamma-glutamyltransferase
NBH81_15140	COG2974	May be involved in recombination
NBH81_15150	COG0420	3'-5' exonuclease activity
NBH81_15160	COG3384	dioxygenase
NBH81_15170	COG0469	pyruvate kinase activity
NBH81_15175	COG3264	Mechanosensitive ion channel
NBH81_15175	COG1196	nuclear chromosome segregation
NBH81_15185	COG3590	peptidase
NBH81_15190	COG3706	GGDEF domain
NBH81_15195	COG2190	(PTS) system
NBH81_15205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_15210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NBH81_15215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NBH81_15230	COG2770	Histidine kinase
NBH81_15230	COG3437	response regulator, receiver
NBH81_15235	COG3267	Type II secretory pathway component ExeA
NBH81_15235	COG3409	Peptidoglycan-binding domain 1 protein
NBH81_15250	COG1450	Type ii and iii secretion system protein
NBH81_15255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NBH81_15260	COG1459	type II secretion system
NBH81_15265	COG2165	general secretion pathway protein
NBH81_15275	COG2165	general secretion pathway protein
NBH81_15285	COG3156	type II secretion system protein K
NBH81_15295	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NBH81_15305	COG0582	viral genome integration into host DNA
NBH81_15350	COG3311	Transcriptional regulator
NBH81_15470	COG2003	Belongs to the UPF0758 family
NBH81_15550	COG1136	(ABC) transporter
NBH81_15560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NBH81_15570	COG2314	TM2 domain
NBH81_15585	COG0670	Belongs to the BI1 family
NBH81_15590	COG1289	transmembrane transporter activity
NBH81_15595	COG2920	part of a sulfur-relay system
NBH81_15600	COG0673	inositol 2-dehydrogenase activity
NBH81_15605	COG0583	DNA-binding transcription factor activity
NBH81_15635	COG3152	Membrane
NBH81_15675	COG1032	radical SAM domain protein
NBH81_15680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NBH81_15685	COG1566	PFAM secretion protein HlyD family protein
NBH81_15690	COG3706	GGDEF domain
NBH81_15695	COG1752	Esterase of the alpha-beta hydrolase superfamily
NBH81_15700	COG0531	amino acid
NBH81_15725	COG0281	malic enzyme
NBH81_15735	COG0534	Mate efflux family protein
NBH81_15750	COG2233	PERMEase
NBH81_15755	COG0095	Lipoate-protein ligase
NBH81_15760	COG1115	amino acid carrier protein
NBH81_15765	COG0019	diaminopimelate decarboxylase activity
NBH81_15775	COG0678	peroxiredoxin activity
NBH81_15800	COG0545	Peptidyl-prolyl cis-trans isomerase
NBH81_15805	COG3142	Participates in the control of copper homeostasis
NBH81_15830	COG5002	protein histidine kinase activity
NBH81_15835	COG0745	RESPONSE REGULATOR receiver
NBH81_15840	COG0346	lactoylglutathione lyase activity
NBH81_15845	COG3284	Transcriptional regulator
NBH81_15860	COG0697	spore germination
NBH81_15870	COG3290	protein histidine kinase activity
NBH81_15875	COG0281	malic enzyme
NBH81_15890	COG1846	Transcriptional regulator
NBH81_15895	COG1566	PFAM secretion protein HlyD family protein
NBH81_15925	COG0602	queuosine metabolic process
NBH81_15930	COG1328	CTP reductase activity
NBH81_15940	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NBH81_15945	COG3115	cell septum assembly
NBH81_15950	COG1196	nuclear chromosome segregation
NBH81_15960	COG2860	membrane
NBH81_15970	COG3108	Peptidase M15
NBH81_15975	COG2989	Protein conserved in bacteria
NBH81_15990	COG0463	Glycosyl transferase, family 2
NBH81_16005	COG0366	Alpha amylase catalytic
NBH81_16040	COG2199	diguanylate cyclase activity
NBH81_16040	COG2203	Gaf domain
NBH81_16050	COG3590	peptidase
NBH81_16060	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NBH81_16065	COG1982	Orn Lys Arg decarboxylase major
NBH81_16070	COG0531	amino acid
NBH81_16075	COG3710	Transcriptional regulator
NBH81_16080	COG0531	amino acid
NBH81_16100	COG0814	amino acid
NBH81_16130	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NBH81_16140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NBH81_16165	COG0583	DNA-binding transcription factor activity
NBH81_16170	COG0604	alcohol dehydrogenase
NBH81_16170	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_16170	COG3321	synthase
NBH81_16190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NBH81_16200	COG3091	SprT-like family
NBH81_16210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NBH81_16215	COG0189	ligase activity
NBH81_16220	COG1678	Uncharacterized ACR, COG1678
NBH81_16225	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NBH81_16230	COG3104	oligopeptide transport
NBH81_16245	COG0714	Associated with various cellular activities
NBH81_16260	COG1115	amino acid carrier protein
NBH81_16265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NBH81_16275	COG0825	malonyl-CoA metabolic process
NBH81_16285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NBH81_16290	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NBH81_16295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NBH81_16300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NBH81_16305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NBH81_16320	COG0750	zinc metalloprotease
NBH81_16325	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NBH81_16330	COG0575	Belongs to the CDS family
NBH81_16335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NBH81_16340	COG0233	cytoplasmic translational termination
NBH81_16345	COG0528	UMP kinase activity
NBH81_16350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NBH81_16355	COG0052	Belongs to the universal ribosomal protein uS2 family
NBH81_16360	COG0024	Methionine aminopeptidase
NBH81_16370	COG2171	N-acyltransferase activity
NBH81_16380	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_16380	COG1263	PTS System
NBH81_16400	COG0564	pseudouridine synthase activity
NBH81_16405	COG3098	single-species biofilm formation
NBH81_16430	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NBH81_16440	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NBH81_16440	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NBH81_16455	COG1611	Belongs to the LOG family
NBH81_16460	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBH81_16465	COG0473	3-isopropylmalate dehydrogenase activity
NBH81_16475	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NBH81_16480	COG2363	Small membrane protein
NBH81_16490	COG0583	DNA-binding transcription factor activity
NBH81_16495	COG0840	transmembrane signaling receptor activity
NBH81_16500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NBH81_16515	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NBH81_16520	COG1666	GTP binding
NBH81_16530	COG2211	Major facilitator Superfamily
NBH81_16535	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NBH81_16545	COG2813	Specifically methylates the guanine in position
NBH81_16550	COG0271	Belongs to the BolA IbaG family
NBH81_16555	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NBH81_16560	COG1805	sodium ion transport
NBH81_16565	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NBH81_16570	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NBH81_16575	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NBH81_16580	COG2871	sodium ion transport
NBH81_16585	COG1477	protein flavinylation
NBH81_16615	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NBH81_16630	COG0300	oxidoreductase activity
NBH81_16640	COG0415	Belongs to the DNA photolyase family
NBH81_16645	COG0789	Transcriptional regulator
NBH81_16650	COG3272	Protein of unknown function (DUF1722)
NBH81_16680	COG0077	Prephenate dehydratase
NBH81_16680	COG1605	Chorismate mutase
NBH81_16710	COG0840	transmembrane signaling receptor activity
NBH81_16725	COG0300	oxidoreductase activity
NBH81_16790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NBH81_16795	COG0826	peptidase U32
NBH81_16800	COG1280	lysine exporter protein (LysE YggA)
NBH81_16810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NBH81_16820	COG0745	RESPONSE REGULATOR receiver
NBH81_16830	COG2198	Histidine kinase
NBH81_16830	COG0643	Histidine kinase
NBH81_16840	COG0835	chemotaxis
NBH81_16845	COG0840	transmembrane signaling receptor activity
NBH81_16855	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NBH81_16860	COG2201	protein-glutamate methylesterase activity
NBH81_16870	COG2814	Major facilitator Superfamily
NBH81_16875	COG4771	TonB-dependent receptor
NBH81_16895	COG0748	coenzyme F420 binding
NBH81_16900	COG3721	Heme iron utilization protein
NBH81_16910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBH81_16925	COG3340	Belongs to the peptidase S51 family
NBH81_16935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NBH81_16950	COG0737	Belongs to the 5'-nucleotidase family
NBH81_16970	COG2204	response regulator
NBH81_16975	COG0545	Peptidyl-prolyl cis-trans isomerase
NBH81_16985	COG2900	Belongs to the SlyX family
NBH81_16990	COG1047	Peptidyl-prolyl cis-trans
NBH81_16995	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NBH81_17005	COG0784	Response regulator, receiver
NBH81_17005	COG0835	chemotaxis
NBH81_17010	COG0429	hydrolase of the alpha beta-hydrolase fold
NBH81_17015	COG2203	Gaf domain
NBH81_17015	COG5001	Diguanylate cyclase
NBH81_17015	COG4251	negative regulation of phosphorylation
NBH81_17015	COG3706	GGDEF domain
NBH81_17020	COG3089	Belongs to the UPF0270 family
NBH81_17025	COG3954	Phosphoribulokinase
NBH81_17040	COG1765	OsmC-like protein
NBH81_17080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBH81_17085	COG2313	pseudouridylate synthase activity
NBH81_17110	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NBH81_17130	COG0569	domain protein
NBH81_17130	COG2985	domain, Protein
NBH81_17135	COG1272	protein, Hemolysin III
NBH81_17140	COG0076	glutamate decarboxylase activity
NBH81_17145	COG2917	probably involved in intracellular septation
NBH81_17150	COG2350	Protein conserved in bacteria
NBH81_17160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NBH81_17165	COG1381	Involved in DNA repair and RecF pathway recombination
NBH81_17180	COG0681	Belongs to the peptidase S26 family
NBH81_17185	COG0481	GTPase activity
NBH81_17195	COG3026	antisigma factor binding
NBH81_17200	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NBH81_17205	COG1595	DNA-templated transcription, initiation
NBH81_17210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NBH81_17220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NBH81_17225	COG0354	folic acid binding
NBH81_17265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NBH81_17270	COG0191	fructose-bisphosphate aldolase activity
NBH81_17275	COG0126	phosphoglycerate kinase activity
NBH81_17280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NBH81_17285	COG1940	carbohydrate kinase activity
NBH81_17290	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NBH81_17295	COG2816	NAD+ diphosphatase activity
NBH81_17305	COG4991	sh3 domain protein
NBH81_17310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NBH81_17320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NBH81_17325	COG0840	transmembrane signaling receptor activity
NBH81_17335	COG1278	Cold shock
NBH81_17370	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NBH81_17375	COG1162	GTPase activity
NBH81_17380	COG0688	phosphatidylethanolamine metabolic process
NBH81_17385	COG4628	conserved protein (DUF2132)
NBH81_17400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NBH81_17415	COG1073	alpha beta
NBH81_17420	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NBH81_17425	COG2195	Cleaves the N-terminal amino acid of tripeptides
NBH81_17430	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NBH81_17435	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NBH81_17440	COG3178	'Phosphotransferase
NBH81_17445	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NBH81_17450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NBH81_17455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NBH81_17460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NBH81_17465	COG2967	ApaG domain
NBH81_17470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NBH81_17485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NBH81_17495	COG3314	Sporulation integral membrane protein YlbJ
NBH81_17500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NBH81_17505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NBH81_17510	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NBH81_17515	COG0142	geranyltranstransferase activity
NBH81_17520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NBH81_17525	COG0330	HflC and HflK could
NBH81_17530	COG0330	HflC and HflK could
NBH81_17535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NBH81_17540	COG1923	regulation of RNA biosynthetic process
NBH81_17545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NBH81_17550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NBH81_17560	COG0802	atpase or kinase
NBH81_17565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NBH81_17565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NBH81_17585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NBH81_17590	COG2011	ABC-type metal ion transport system permease component
NBH81_17595	COG1464	Belongs to the NlpA lipoprotein family
NBH81_17605	COG0840	transmembrane signaling receptor activity
NBH81_17630	COG0784	Response regulator, receiver
NBH81_17630	COG2198	Histidine kinase
NBH81_17630	COG5002	protein histidine kinase activity
NBH81_17665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NBH81_17670	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NBH81_17675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NBH81_17680	COG2716	regulation of RNA biosynthetic process
NBH81_17685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NBH81_17690	COG3013	Belongs to the UPF0304 family
NBH81_17700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NBH81_17705	COG0280	phosphate acetyltransferase
NBH81_17705	COG0857	belongs to the CobB CobQ family
NBH81_17710	COG1555	photosystem II stabilization
NBH81_17715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NBH81_17720	COG3104	oligopeptide transport
NBH81_17725	COG0745	RESPONSE REGULATOR receiver
NBH81_17755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NBH81_17770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NBH81_17780	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NBH81_17795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NBH81_17840	COG2003	Belongs to the UPF0758 family
NBH81_17940	COG3311	Transcriptional regulator
NBH81_17985	COG0440	acetolactate synthase activity
NBH81_17990	COG0028	Belongs to the TPP enzyme family
NBH81_18005	COG0671	phosphoesterase, PA-phosphatase related
NBH81_18015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NBH81_18020	COG0473	3-isopropylmalate dehydrogenase activity
NBH81_18025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NBH81_18030	COG0066	3-isopropylmalate dehydratase activity
NBH81_18045	COG4143	(ABC) transporter
NBH81_18055	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NBH81_18060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NBH81_18110	COG0459	protein refolding
NBH81_18115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NBH81_18120	COG0534	Mate efflux family protein
NBH81_18125	COG3030	protein affecting phage T7 exclusion by the F plasmid
NBH81_18130	COG1027	Aspartate ammonia-lyase
NBH81_18135	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NBH81_18140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NBH81_18145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NBH81_18150	COG1610	YqeY-like protein
NBH81_18155	COG0358	DNA primase activity
NBH81_18160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NBH81_18170	COG0582	viral genome integration into host DNA
NBH81_18220	COG0151	Belongs to the GarS family
NBH81_18225	COG0138	bifunctional purine biosynthesis protein purh
NBH81_18235	COG3036	rescue of stalled ribosome
NBH81_18240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NBH81_18245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NBH81_18255	COG0673	inositol 2-dehydrogenase activity
NBH81_18265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBH81_18270	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBH81_18280	COG0583	DNA-binding transcription factor activity
NBH81_18285	COG0477	Major facilitator Superfamily
NBH81_18310	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_18320	COG2425	protein containing a von Willebrand factor type A (vWA) domain
NBH81_18335	COG0456	acetyltransferase
NBH81_18345	COG1022	Amp-dependent synthetase and ligase
NBH81_18355	COG2918	glutathione biosynthetic process
NBH81_18360	COG0612	Peptidase, M16
NBH81_18365	COG1238	metal cluster binding
NBH81_18370	COG1064	alcohol dehydrogenase
NBH81_18395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NBH81_18400	COG0359	binds to the 23S rRNA
NBH81_18405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NBH81_18410	COG0360	Binds together with S18 to 16S ribosomal RNA
NBH81_18415	COG1914	H( )-stimulated, divalent metal cation uptake system
NBH81_18420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBH81_18430	COG0776	regulation of translation
NBH81_18445	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NBH81_18460	COG0560	Phosphoserine phosphatase
NBH81_18470	COG0813	purine-nucleoside phosphorylase activity
NBH81_18475	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NBH81_18480	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NBH81_18485	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NBH81_18495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NBH81_18500	COG0084	hydrolase, TatD family'
NBH81_18505	COG2165	general secretion pathway protein
NBH81_18510	COG1854	S-ribosylhomocysteine lyase activity
NBH81_18525	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NBH81_18525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBH81_18570	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NBH81_18575	COG1047	Peptidyl-prolyl cis-trans
NBH81_18580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NBH81_18585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NBH81_18590	COG0196	riboflavin kinase activity
NBH81_18595	COG0728	peptidoglycan biosynthetic process
NBH81_18600	COG0268	Binds directly to 16S ribosomal RNA
NBH81_18605	COG0640	Transcriptional regulator
NBH81_18610	COG0583	DNA-binding transcription factor activity
NBH81_18620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NBH81_18625	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NBH81_18630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NBH81_18640	COG1051	belongs to the nudix hydrolase family
NBH81_18645	COG3066	DNA modification
NBH81_18655	COG0335	large ribosomal subunit rRNA binding
NBH81_18660	COG0336	Belongs to the RNA methyltransferase TrmD family
NBH81_18665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NBH81_18670	COG0228	four-way junction DNA binding
NBH81_18675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NBH81_18680	COG4137	Cytochrome C assembly protein
NBH81_18685	COG4536	flavin adenine dinucleotide binding
NBH81_18695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NBH81_18695	COG1017	nitric oxide dioxygenase activity
NBH81_18700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NBH81_18705	COG0039	L-malate dehydrogenase activity
NBH81_18710	COG4160	amino acid transport
NBH81_18715	COG4215	(ABC) transporter
NBH81_18720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_18725	COG1126	abc transporter atp-binding protein
NBH81_18730	COG1438	arginine binding
NBH81_18735	COG2837	iron assimilation
NBH81_18740	COG3842	ATPase activity
NBH81_18750	COG1840	ABC-type Fe3 transport system, periplasmic component
NBH81_18755	COG0347	Belongs to the P(II) protein family
NBH81_18775	COG3022	response to hydroperoxide
NBH81_18790	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NBH81_18795	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NBH81_18800	COG0762	integral membrane protein
NBH81_18805	COG1872	DUF167
NBH81_18815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NBH81_18820	COG0583	DNA-binding transcription factor activity
NBH81_18835	COG1929	Belongs to the glycerate kinase type-1 family
NBH81_18840	COG2610	gluconate transmembrane transporter activity
NBH81_18845	COG3835	regulator
NBH81_18850	COG3112	Uncharacterised protein family (UPF0231)
NBH81_18870	COG3568	Endonuclease Exonuclease Phosphatase
NBH81_18880	COG0513	Belongs to the DEAD box helicase family
NBH81_18905	COG0204	Acyl-transferase
NBH81_18925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NBH81_18930	COG0583	DNA-binding transcription factor activity
NBH81_18935	COG2084	Dehydrogenase
NBH81_18965	COG3104	oligopeptide transport
NBH81_18985	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NBH81_19005	COG3150	esterase
NBH81_19015	COG3151	Protein conserved in bacteria
NBH81_19020	COG0494	nUDIX hydrolase
NBH81_19025	COG1538	Outer membrane efflux protein
NBH81_19030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NBH81_19030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NBH81_19035	COG1560	Kdo2-lipid A biosynthetic process
NBH81_19050	COG2213	PTS system mannitol-specific
NBH81_19050	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NBH81_19055	COG0246	Mannitol dehydrogenase
NBH81_19060	COG3722	fumarate hydratase activity
NBH81_19070	COG0484	heat shock protein binding
NBH81_19090	COG1671	Belongs to the UPF0178 family
NBH81_19095	COG1988	membrane-bound metal-dependent
NBH81_19105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NBH81_19110	COG0513	Belongs to the DEAD box helicase family
NBH81_19130	COG1575	Belongs to the MenA family. Type 1 subfamily
NBH81_19135	COG1169	isochorismate synthase
NBH81_19140	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NBH81_19145	COG0596	Alpha beta hydrolase
NBH81_19150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NBH81_19155	COG1441	menaquinone biosynthetic process
NBH81_19160	COG0318	PFAM AMP-dependent synthetase and ligase
NBH81_19165	COG3291	Pkd domain containing protein
NBH81_19170	COG2949	membrane
NBH81_19175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NBH81_19185	COG0835	chemotaxis
NBH81_19185	COG0784	Response regulator, receiver
NBH81_19195	COG1444	tRNA N-acetyltransferase activity
NBH81_19215	COG1803	Methylglyoxal synthase
NBH81_19220	COG1979	alcohol dehydrogenase
NBH81_19235	COG4221	oxidoreductase activity
NBH81_19275	COG1368	sulfuric ester hydrolase activity
NBH81_19280	COG1522	sequence-specific DNA binding
NBH81_19290	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NBH81_19300	COG1058	Belongs to the CinA family
NBH81_19300	COG1546	Belongs to the CinA family
NBH81_19310	COG0561	phosphatase activity
NBH81_19320	COG3385	transposase activity
NBH81_19325	COG2926	Belongs to the UPF0265 family
NBH81_19360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NBH81_19365	COG0564	pseudouridine synthase activity
NBH81_19375	COG0110	maltose O-acetyltransferase activity
NBH81_19380	COG0366	Alpha amylase catalytic
NBH81_19385	COG1263	PTS System
NBH81_19385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NBH81_19405	COG0252	asparaginase activity
NBH81_19415	COG1253	flavin adenine dinucleotide binding
NBH81_19420	COG0586	Pfam SNARE associated Golgi protein
NBH81_19425	COG1686	Belongs to the peptidase S11 family
NBH81_19450	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NBH81_19455	COG0527	aspartate kinase activity
NBH81_19460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NBH81_19470	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NBH81_19475	COG1546	Belongs to the CinA family
NBH81_19495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NBH81_19510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NBH81_19515	COG4667	esterase of the alpha-beta hydrolase superfamily
NBH81_19525	COG1346	cytolysis
NBH81_19530	COG1380	Effector of murein hydrolase LrgA
NBH81_19535	COG0583	DNA-binding transcription factor activity
NBH81_19545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NBH81_19555	COG1192	Involved in chromosome partitioning
NBH81_19565	COG1943	Transposase
NBH81_19570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NBH81_19575	COG2022	thiamine diphosphate biosynthetic process
NBH81_19585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NBH81_19590	COG0352	thiamine-phosphate diphosphorylase activity
NBH81_19595	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NBH81_19615	COG0745	RESPONSE REGULATOR receiver
NBH81_19625	COG0189	ligase activity
NBH81_19670	COG0477	Major facilitator Superfamily
NBH81_19695	COG0235	Class ii aldolase
NBH81_19710	COG0738	Major facilitator superfamily
NBH81_19715	COG1349	DNA-binding transcription factor activity
NBH81_19725	COG0312	modulator of DNA gyrase
NBH81_19730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NBH81_19745	COG3164	Protein of unknown function
NBH81_19750	COG1530	ribonuclease E activity
NBH81_19755	COG0424	maF-like protein
NBH81_19760	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NBH81_19765	COG1792	Involved in formation and maintenance of cell shape
NBH81_19770	COG1077	Cell shape determining protein MreB Mrl
NBH81_19795	COG4968	Prepilin-type N-terminal cleavage methylation domain
NBH81_19800	COG4968	Prepilin-type N-terminal cleavage methylation domain
NBH81_19815	COG1459	type II secretion system
NBH81_19820	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NBH81_19865	COG2199	diguanylate cyclase activity
NBH81_19865	COG2200	EAL domain
NBH81_19870	COG2200	EAL domain
NBH81_19875	COG0387	Pfam Sodium calcium exchanger
NBH81_19880	COG2986	histidine ammonia-lyase
NBH81_19885	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NBH81_19890	COG0010	Belongs to the arginase family
NBH81_19895	COG1228	amidohydrolase
NBH81_19900	COG2188	Transcriptional regulator
NBH81_19905	COG0288	reversible hydration of carbon dioxide
NBH81_19915	COG2177	Part of the ABC transporter FtsEX involved in
NBH81_19920	COG2884	Cell division ATP-binding protein ftsE
NBH81_19925	COG0552	protein localization to endoplasmic reticulum
NBH81_19930	COG0742	ribosomal rna small subunit methyltransferase
NBH81_19955	COG2249	NAD(P)H dehydrogenase (quinone) activity
NBH81_19960	COG0583	DNA-binding transcription factor activity
NBH81_19965	COG4221	oxidoreductase activity
NBH81_19980	COG1770	oligopeptidase
NBH81_19995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NBH81_20005	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NBH81_20015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NBH81_20025	COG2095	MarC family integral membrane protein
NBH81_20035	COG1301	dicarboxylic acid transport
NBH81_20060	COG3714	YhhN family
NBH81_20115	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NBH81_20120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBH81_20125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NBH81_20130	COG0049	tRNA binding
NBH81_20135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NBH81_20140	COG2168	tRNA wobble position uridine thiolation
NBH81_20145	COG2923	Belongs to the DsrF TusC family
NBH81_20150	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NBH81_20160	COG2964	Protein conserved in bacteria
NBH81_20165	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NBH81_20170	COG0085	RNA polymerase activity
NBH81_20175	COG0222	ribosome binding
NBH81_20180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NBH81_20185	COG0081	regulation of translation
NBH81_20190	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NBH81_20195	COG0250	Participates in transcription elongation, termination and antitermination
NBH81_20210	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NBH81_20235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NBH81_20240	COG0569	domain protein
NBH81_20245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NBH81_20275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NBH81_20275	COG4191	Histidine kinase
NBH81_20280	COG3005	denitrification pathway
NBH81_20285	COG0243	molybdopterin cofactor binding
NBH81_20330	COG2204	response regulator
NBH81_20340	COG2205	protein histidine kinase activity
NBH81_20355	COG1028	Short-chain dehydrogenase reductase Sdr
NBH81_20360	COG0516	GMP reductase activity
NBH81_20360	COG0517	IMP dehydrogenase activity
NBH81_20365	COG5413	integral membrane protein
NBH81_20375	COG1522	sequence-specific DNA binding
NBH81_20380	COG2502	aspartate--ammonia ligase
NBH81_20390	COG0542	response to heat
NBH81_20400	COG0564	pseudouridine synthase activity
NBH81_20405	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NBH81_20410	COG0446	pyridine nucleotide-disulphide oxidoreductase
NBH81_20420	COG3681	Belongs to the UPF0597 family
NBH81_20425	COG2964	Protein conserved in bacteria
NBH81_20435	COG4974	Belongs to the 'phage' integrase family
NBH81_20510	COG5002	protein histidine kinase activity
NBH81_20510	COG2176	DNA-directed DNA polymerase activity
NBH81_20545	COG4695	Portal protein
NBH81_20595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NBH81_20675	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NBH81_20680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NBH81_20685	COG1979	alcohol dehydrogenase
NBH81_20690	COG2207	Transcriptional regulator
NBH81_20695	COG3040	lipid binding
NBH81_20710	COG0583	DNA-binding transcription factor activity
NBH81_20730	COG0540	Belongs to the ATCase OTCase family
NBH81_20735	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NBH81_20740	COG1438	arginine binding
NBH81_20745	COG1288	antiporter activity
NBH81_20750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NBH81_20780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NBH81_20790	COG3078	GTPase activator activity
NBH81_20800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NBH81_20810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NBH81_20815	COG0408	coproporphyrinogen oxidase activity
NBH81_20820	COG0009	L-threonylcarbamoyladenylate synthase
NBH81_20830	COG0551	DNA topoisomerase type I activity
NBH81_20835	COG2922	Belongs to the Smg family
NBH81_20840	COG0758	DNA mediated transformation
NBH81_20845	COG1652	LysM domain
NBH81_20850	COG0242	peptide deformylase activity
NBH81_20855	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NBH81_20860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NBH81_20860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NBH81_20865	COG0569	domain protein
NBH81_20870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NBH81_20875	COG1217	gtp-binding protein TYPA
NBH81_20880	COG0174	glutamine synthetase
NBH81_20895	COG2204	response regulator
NBH81_20900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NBH81_20905	COG1322	Protein conserved in bacteria
NBH81_20925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NBH81_20930	COG0583	DNA-binding transcription factor activity
NBH81_20935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NBH81_20935	COG0519	Catalyzes the synthesis of GMP from XMP
NBH81_20945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NBH81_20950	COG1396	sequence-specific DNA binding
NBH81_20955	COG1012	belongs to the aldehyde dehydrogenase family
NBH81_20965	COG2962	Rard protein
NBH81_20975	COG2391	methyltransferase activity
NBH81_20980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NBH81_20980	COG2885	chlorophyll binding
NBH81_20990	COG0129	dihydroxy-acid dehydratase activity
NBH81_21000	COG3978	acetolactate synthase activity
NBH81_21010	COG0606	chelatase, subunit chli
NBH81_21015	COG0204	Acyl-transferase
NBH81_21020	COG0204	Acyl-transferase
NBH81_21025	COG1683	Conserved Protein
NBH81_21035	COG1335	isochorismatase
NBH81_21045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NBH81_21050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NBH81_21060	COG3084	Protein conserved in bacteria
NBH81_21065	COG5001	Diguanylate cyclase
NBH81_21065	COG2203	Gaf domain
NBH81_21065	COG3706	GGDEF domain
NBH81_21065	COG4251	negative regulation of phosphorylation
NBH81_21080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NBH81_21085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NBH81_21090	COG1561	YicC-like family, N-terminal region
NBH81_21095	COG0583	DNA-binding transcription factor activity
NBH81_21115	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NBH81_21120	COG0385	Bile acid
NBH81_21125	COG0531	amino acid
NBH81_21130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NBH81_21140	COG2731	YhcH YjgK YiaL family protein
NBH81_21145	COG3250	beta-galactosidase activity
NBH81_21150	COG1609	Transcriptional regulator
NBH81_21185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NBH81_21190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBH81_21190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NBH81_21195	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NBH81_21200	COG3074	FtsZ-dependent cytokinesis
NBH81_21210	COG1045	serine acetyltransferase
NBH81_21220	COG0745	RESPONSE REGULATOR receiver
NBH81_21225	COG2205	protein histidine kinase activity
NBH81_21230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NBH81_21235	COG0534	Mate efflux family protein
NBH81_21250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NBH81_21255	COG2937	Belongs to the GPAT DAPAT family
NBH81_21260	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NBH81_21265	COG3161	chorismate lyase activity
NBH81_21295	COG0604	alcohol dehydrogenase
NBH81_21300	COG1519	Transferase
NBH81_21305	COG0859	PFAM glycosyl transferase family 9
NBH81_21310	COG0463	Glycosyl transferase, family 2
NBH81_21315	COG0859	PFAM glycosyl transferase family 9
NBH81_21320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NBH81_21325	COG2990	Protein conserved in bacteria
NBH81_21330	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NBH81_21340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NBH81_21345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NBH81_21350	COG2003	Belongs to the UPF0758 family
NBH81_21360	COG0756	dUTP diphosphatase activity
NBH81_21365	COG1309	transcriptional regulator
NBH81_21370	COG0668	transmembrane transport
NBH81_21375	COG0166	Belongs to the GPI family
NBH81_21380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NBH81_21400	COG0045	succinate-CoA ligase (ADP-forming) activity
NBH81_21400	COG1042	CoA-binding domain protein
NBH81_21400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NBH81_21430	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NBH81_21435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NBH81_21440	COG1739	Uncharacterized protein family UPF0029
NBH81_21445	COG0006	proline dipeptidase activity
NBH81_21450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NBH81_21455	COG1024	Enoyl-CoA hydratase
NBH81_21455	COG1250	3-hydroxyacyl-CoA dehydrogenase
NBH81_21460	COG0183	Belongs to the thiolase family
NBH81_21485	COG0425	Belongs to the sulfur carrier protein TusA family
NBH81_21490	COG0251	oxidation-reduction process
NBH81_21495	COG2885	chlorophyll binding
NBH81_21500	COG2818	Glycosylase
NBH81_21505	COG0752	glycyl-tRNA synthetase alpha subunit
NBH81_21510	COG0751	glycine-tRNA ligase activity
NBH81_21525	COG2199	diguanylate cyclase activity
NBH81_21525	COG2200	EAL domain
NBH81_21525	COG2202	Pas domain
NBH81_21570	COG1609	Transcriptional regulator
NBH81_21600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NBH81_21610	COG2960	long-chain fatty acid transporting porin activity
NBH81_21615	COG5001	Diguanylate cyclase
NBH81_21625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NBH81_21640	COG3118	belongs to the thioredoxin family
NBH81_21645	COG0513	Belongs to the DEAD box helicase family
NBH81_21650	COG0248	Ppx GppA phosphatase
NBH81_21660	COG0742	ribosomal rna small subunit methyltransferase
NBH81_21675	COG3469	chitinase activity
NBH81_21680	COG3397	chitin binding
NBH81_21690	COG0084	hydrolase, TatD family'
NBH81_21695	COG0805	protein transport
NBH81_21700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NBH81_21705	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NBH81_21710	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NBH81_21715	COG3165	ubiquinone biosynthetic process from chorismate
NBH81_21720	COG2226	methyltransferase
NBH81_21725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NBH81_21730	COG0402	S-adenosylhomocysteine deaminase activity
NBH81_21735	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NBH81_21770	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NBH81_21775	COG0848	biopolymer transport protein
NBH81_21780	COG0811	peptide transport
NBH81_21785	COG0811	peptide transport
NBH81_21795	COG2771	luxR family
NBH81_21800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NBH81_21805	COG1349	DNA-binding transcription factor activity
NBH81_21810	COG0745	RESPONSE REGULATOR receiver
NBH81_21815	COG2205	protein histidine kinase activity
NBH81_21825	COG4452	Inner membrane protein CreD
NBH81_21840	COG0297	glycogen (starch) synthase activity
NBH81_21840	COG0438	transferase activity, transferring glycosyl groups
NBH81_21885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NBH81_21890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NBH81_21895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NBH81_21900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NBH81_21905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NBH81_21910	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NBH81_21915	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NBH81_21920	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NBH81_21930	COG0356	it plays a direct role in the translocation of protons across the membrane
NBH81_21940	COG1475	DNA binding
NBH81_21945	COG1192	Involved in chromosome partitioning
NBH81_21950	COG0357	Ribosomal RNA small subunit methyltransferase G
NBH81_21955	COG0445	tRNA wobble uridine modification
NBH81_21960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NBH81_21970	COG4615	Cyclic peptide transporter
NBH81_21975	COG1120	ATPase activity
NBH81_21980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NBH81_21985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NBH81_21990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NBH81_21995	COG0706	membrane insertase activity
NBH81_22000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NBH81_22005	COG0594	ribonuclease P activity
NBH81_22010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NBH81_22015	COG1126	abc transporter atp-binding protein
NBH81_22040	COG3077	Addiction module antitoxin, RelB DinJ family
NBH81_22045	COG2026	Addiction module toxin, RelE StbE family
NBH81_22050	COG2944	sequence-specific DNA binding
NBH81_22060	COG1192	Involved in chromosome partitioning