locus-tag	class	description
ACAM_0003	ENOG4105C59	p-type ATPase
ACAM_0005	ENOG4107RY6	amino acid
ACAM_0007	ENOG4105D7K	pfkb domain protein
ACAM_0008	ENOG4105C01	Dihydroxy-acid dehydratase
ACAM_0010	ENOG4105CMG	Carbohydrate kinase
ACAM_0017	ENOG4105K63	Thioredoxin
ACAM_0020	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ACAM_0024	ENOG4107YY3	extracellular solute-binding protein family 1
ACAM_0025	ENOG4105S9S	Binding-protein-dependent transport systems, inner membrane component
ACAM_0026	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
ACAM_0027	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACAM_0028	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ACAM_0029	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ACAM_0030	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACAM_0032	ENOG4107S1N	anthranilate phosphoribosyltransferase
ACAM_0033	ENOG4105CRQ	synthase (Component I)
ACAM_0034	ENOG4105DDQ	anthranilate synthase
ACAM_0036	ENOG4105C8U	phosphate abc transporter
ACAM_0037	ENOG4105E2Z	phosphate ABC transporter (Permease
ACAM_0038	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
ACAM_0041	ENOG4105ERH	Fumarylacetoacetate hydrolase
ACAM_0044	ENOG4105E39	Enoyl-CoA hydratase
ACAM_0046	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
ACAM_0048	ENOG4105C2J	ABC transporter
ACAM_0058	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACAM_0060	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
ACAM_0063	ENOG4108DBC	nitroreductase
ACAM_0066	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACAM_0070	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
ACAM_0071	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
ACAM_0076	ENOG4105CQ2	DNA polymerase
ACAM_0077	ENOG4105DF6	Fe-S oxidoreductase
ACAM_0081	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
ACAM_0085	ENOG4107WZZ	SMC domain protein
ACAM_0085	ENOG4107WZZ	SMC domain protein
ACAM_0092	ENOG4105C22	threonyL-tRNA synthetase
ACAM_0093	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ACAM_0099	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ACAM_0105	ENOG4105C10	Electron transfer flavoprotein
ACAM_0107	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ACAM_0109	ENOG4105DR4	Methyltransferase
ACAM_0126	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
ACAM_0129	ENOG4105C26	Dehydrogenase
ACAM_0133	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
ACAM_0134	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ACAM_0135	ENOG4105BZA	Phosphoglycerate kinase
ACAM_0138	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
ACAM_0139	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
ACAM_0141	ENOG4105CY0	Metallo-Beta-Lactamase
ACAM_0142	ENOG4105VZ9	UPF0235 protein
ACAM_0147	ENOG4105CQR	helicase
ACAM_0148	ENOG4108535	NAD dependent epimerase/dehydratase family
ACAM_0154	ENOG4105DFU	Cell wall formation (By similarity)
ACAM_0156	ENOG4107QRT	dEAD DEAH box helicase
ACAM_0165	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
ACAM_0166	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACAM_0170	ENOG4105CR4	methylisocitrate lyase
ACAM_0174	ENOG41082UH	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ACAM_0175	ENOG4105D1F	ATP-binding protein
ACAM_0178	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACAM_0180	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ACAM_0187	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
ACAM_0188	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
ACAM_0189	ENOG4105E63	Pfam:DUF178
ACAM_0190	ENOG4105DVY	radical SAM domain protein
ACAM_0191	ENOG4105DVY	radical SAM domain protein
ACAM_0193	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
ACAM_0198	ENOG4107QR9	Iron-sulfur cluster binding protein
ACAM_0199	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
ACAM_0201	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
ACAM_0202	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
ACAM_0206	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ACAM_0220	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACAM_0229	ENOG4105CQB	FAD linked oxidase domain protein
ACAM_0233	ENOG4105CYC	Transferase
ACAM_0235	ENOG4108R96	Methyltransferase, YaeB family
ACAM_0237	ENOG4105CYW	agmatinase
ACAM_0238	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ACAM_0239	ENOG4108Z0Z	intracellular protease Pfpi family
ACAM_0240	ENOG410688J	Ferredoxin
ACAM_0244	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACAM_0246	ENOG4105C5X	domain protein
ACAM_0247	ENOG4105DHP	deoxycytidine triphosphate deaminase
ACAM_0249	ENOG4105CUJ	penicillin amidase
ACAM_0251	ENOG4105FQP	Beta-lactamase
ACAM_0254	ENOG4108S4H	thioesterase Superfamily protein
ACAM_0257	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ACAM_0261	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ACAM_0262	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ACAM_0264	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACAM_0265	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACAM_0266	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ACAM_0267	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ACAM_0270	ENOG41082SA	50s ribosomal protein l29
ACAM_0272	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ACAM_0273	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ACAM_0277	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ACAM_0281	ENOG4105C5X	domain protein
ACAM_0282	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACAM_0284	ENOG4105CSU	acyl-Coa dehydrogenase
ACAM_0287	ENOG4105C6K	Malic enzyme
ACAM_0288	ENOG4105CEY	Amp-dependent synthetase and ligase
ACAM_0293	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
ACAM_0294	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
ACAM_0305	ENOG4108RE7	deoxyribonuclease
ACAM_0309	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
ACAM_0312	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ACAM_0314	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ACAM_0325	ENOG41060GV	RNA binding s1 domain protein
ACAM_0328	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ACAM_0332	ENOG4105PW4	Sugar fermentation stimulation protein homolog
ACAM_0333	ENOG4108JPW	Aminotransferase
ACAM_0346	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ACAM_0349	ENOG4105EW9	transcriptional regulator AsnC family
ACAM_0372	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACAM_0378	ENOG4105CQB	FAD linked oxidase domain protein
ACAM_0385	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACAM_0391	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
ACAM_0394	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACAM_0395	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
ACAM_0397	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ACAM_0399	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ACAM_0400	ENOG4108MDK	Dehydrogenase
ACAM_0401	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
ACAM_0402	ENOG4105CY0	Metallo-Beta-Lactamase
ACAM_0403	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACAM_0406	ENOG4105DC7	peptidase M24
ACAM_0407	ENOG4107SCA	Formamidase (EC 3.5.1.49)
ACAM_0413	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ACAM_0418	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ACAM_0424	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACAM_0425	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
ACAM_0426	ENOG4108T9W	RNA methylase
ACAM_0432	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ACAM_0434	ENOG4105E2X	shikimate dehydrogenase
ACAM_0436	ENOG4105D49	3-dehydroquinate synthase
ACAM_0437	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ACAM_0438	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ACAM_0439	ENOG4108HHA	Transketolase
ACAM_0442	ENOG4105CGU	Enoyl-CoA hydratase
ACAM_0446	ENOG4105CEP	NADH dehydrogenase
ACAM_0460	ENOG4108JW7	Maf-like protein
ACAM_0473	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
ACAM_0475	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
ACAM_0478	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
ACAM_0479	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
ACAM_0480	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
ACAM_0482	ENOG4105K63	Thioredoxin
ACAM_0485	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
ACAM_0491	ENOG4105CUT	histidyl-tRNA synthetase
ACAM_0493	ENOG4105E66	phosphoriboisomerase A
ACAM_0495	ENOG4105ETU	transcriptional activator (TenA
ACAM_0497	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ACAM_0499	ENOG4105CHM	Aminotransferase
ACAM_0500	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACAM_0501	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ACAM_0502	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
ACAM_0510	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
ACAM_0511	ENOG4108HMX	isocitrate dehydrogenase (NADP)
ACAM_0513	ENOG4108EHY	type IV secretion system
ACAM_0515	ENOG4105E0R	Deoxyhypusine synthase
ACAM_0524	ENOG4105DTQ	mandelate racemase muconate lactonizing
ACAM_0525	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
ACAM_0526	ENOG4105C1G	acyl-Coa dehydrogenase
ACAM_0527	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACAM_0534	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ACAM_0538	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ACAM_0549	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
ACAM_0551	ENOG4105CJW	magnesium transporter
ACAM_0558	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ACAM_0559	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ACAM_0565	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ACAM_0567	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACAM_0568	ENOG4105C26	Dehydrogenase
ACAM_0569	ENOG4105C22	threonyL-tRNA synthetase
ACAM_0584	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACAM_0593	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACAM_0595	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACAM_0596	ENOG4105CHR	reductase
ACAM_0601	ENOG4105C0Z	ABC transporter
ACAM_0602	ENOG4108IV0	ABC, transporter
ACAM_0603	ENOG4105CNN	ABC, transporter
ACAM_0606	ENOG4105CHU	acetyl-coa acetyltransferase
ACAM_0611	ENOG4105BZ8	glutamate synthase
ACAM_0615	ENOG4105D38	putrescine abc transporter
ACAM_0616	ENOG4105F38	ABC transporter, permease
ACAM_0617	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACAM_0618	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
ACAM_0619	ENOG4105E33	succinate dehydrogenase
ACAM_0623	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
ACAM_0626	ENOG4105EYW	Ion transport protein
ACAM_0629	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ACAM_0630	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACAM_0641	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACAM_0644	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ACAM_0651	ENOG4107RDF	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ACAM_0653	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ACAM_0654	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ACAM_0655	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
ACAM_0657	ENOG4105D1Z	hydroxypyruvate reductase
ACAM_0667	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
ACAM_0670	ENOG4105C8T	Leucyl-tRNA synthetase
ACAM_0672	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
ACAM_0680	ENOG4105CEP	NADH dehydrogenase
ACAM_0681	ENOG4108DBC	nitroreductase
ACAM_0682	ENOG4105D0M	Protease HtpX homolog
ACAM_0684	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ACAM_0685	ENOG4105EHG	Permease protein
ACAM_0686	ENOG4105DIK	(ABC) transporter
ACAM_0687	ENOG4105NBF	ammecr1 domain protein
ACAM_0689	ENOG4105C3M	thioredoxin reductase
ACAM_0690	ENOG4105C3M	thioredoxin reductase
ACAM_0693	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
ACAM_0694	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
ACAM_0695	ENOG4105CFI	type iii restriction protein res subunit
ACAM_0698	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACAM_0708	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
ACAM_0709	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ACAM_0711	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ACAM_0712	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACAM_0713	ENOG4107NFR	Fructose-1,6-bisphosphatase
ACAM_0716	ENOG4105E8R	UPF0173 metal-dependent hydrolase
ACAM_0717	ENOG4105C2J	ABC transporter
ACAM_0720	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACAM_0723	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACAM_0725	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ACAM_0726	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ACAM_0728	ENOG4105CFH	Aspartokinase
ACAM_0729	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
ACAM_0730	ENOG4105D6E	homoserine dehydrogenase
ACAM_0734	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ACAM_0735	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACAM_0737	ENOG4105C3G	gtp-binding protein
ACAM_0750	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
ACAM_0753	ENOG4107RIQ	Sulfate adenylate transferase
ACAM_0761	ENOG4105CKK	Glycosyl transferase, family 2
ACAM_0763	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ACAM_0764	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
ACAM_0766	ENOG4105C1G	acyl-Coa dehydrogenase
ACAM_0769	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
ACAM_0776	ENOG4105C28	cystathionine
ACAM_0796	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACAM_0797	ENOG4105CJ1	ABC, transporter
ACAM_0802	ENOG4105C5X	domain protein
ACAM_0806	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
ACAM_0819	ENOG4108IUE	nitrate reductase beta subunit
ACAM_0822	ENOG4105R3A	Nitrate reductase
ACAM_0823	ENOG4108IV0	ABC, transporter
ACAM_0825	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ACAM_0827	ENOG4105CEY	Amp-dependent synthetase and ligase
ACAM_0828	ENOG4105C0Z	ABC transporter
ACAM_0829	ENOG410680H	amp-dependent synthetase and ligase
ACAM_0832	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ACAM_0844	ENOG4105CN9	Peptidase m42 family protein
ACAM_0848	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
ACAM_0851	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ACAM_0853	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACAM_0854	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ACAM_0856	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ACAM_0865	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACAM_0869	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
ACAM_0874	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ACAM_0875	ENOG4105D82	Glutamate dehydrogenase
ACAM_0878	ENOG4105DEF	Extracellular solute-binding protein, family 5
ACAM_0879	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACAM_0880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACAM_0882	ENOG4108JQ7	(ABC) transporter
ACAM_0888	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACAM_0890	ENOG4105C8S	subunit m
ACAM_0894	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
ACAM_0895	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACAM_0896	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACAM_0897	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACAM_0899	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ACAM_0900	ENOG4105E59	Participates in a DNA-damage check-point. DisA forms globular foci that rapidly scan along the chromosomes searching for lesions (By similarity)
ACAM_0909	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
ACAM_0910	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ACAM_0912	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
ACAM_0916	ENOG4105C59	p-type ATPase
ACAM_0920	ENOG4105CAS	nag kinase
ACAM_0921	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ACAM_0923	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ACAM_0924	ENOG4105C8Y	Acetylornithine aminotransferase
ACAM_0925	ENOG4108KB0	deacetylase
ACAM_0926	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ACAM_0927	ENOG4107Z8Z	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ACAM_0928	ENOG4105DQU	oxidoreductase, subunit beta
ACAM_0929	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ACAM_0932	ENOG4108YZ4	nudix hydrolase
ACAM_0936	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
ACAM_0937	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ACAM_0941	ENOG4105MRR	Transcriptional regulator (By similarity)
ACAM_0943	ENOG4105C7B	Threonine dehydratase
ACAM_0944	ENOG4105KME	endoribonuclease L-psp
ACAM_0945	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
ACAM_0946	ENOG4105EHU	Circadian clock protein KaiC
ACAM_0947	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACAM_0952	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ACAM_0955	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
ACAM_0956	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ACAM_0957	ENOG4105D1H	recombination factor protein RarA
ACAM_0962	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACAM_0966	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ACAM_0968	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
ACAM_0971	ENOG4105C5Z	peptidase
ACAM_0972	ENOG4108M15	ABC transporter
ACAM_0974	ENOG4105CMQ	Chloride channel
ACAM_0980	ENOG4108T9Q	UPF0278 protein
ACAM_0985	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
ACAM_0986	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ACAM_0991	ENOG4108JQ7	(ABC) transporter
ACAM_0992	ENOG4105C3U	ABC transporter
ACAM_0993	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACAM_0994	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACAM_0997	ENOG4105C6T	cysteine synthase
ACAM_0998	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
ACAM_0999	ENOG4105C8N	cysteinyl-tRNA synthetase
ACAM_1000	ENOG4105D06	uba thif-type nad fad binding protein
ACAM_1002	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
ACAM_1006	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ACAM_1014	ENOG4105E3H	phosphoglycerate mutase
ACAM_1017	ENOG4107QM5	aconitate hydratase
ACAM_1019	ENOG4107RQ2	Cytochrome c oxidase, subunit I
ACAM_1027	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACAM_1029	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
ACAM_1033	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ACAM_1034	ENOG4108UVJ	appr-1-p processing domain protein
ACAM_1042	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
ACAM_1043	ENOG4105CXT	aspartate transcarbamylase
ACAM_1045	ENOG4105VF7	tolerance protein
ACAM_1046	ENOG4107QN2	dihydrolipoyl dehydrogenase
ACAM_1048	ENOG4105CPP	Dehydrogenase, E1 component
ACAM_1050	ENOG4105C1G	acyl-Coa dehydrogenase
ACAM_1052	ENOG4105D5P	Methylmalonyl-coA mutase
ACAM_1060	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
ACAM_1061	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
ACAM_1066	ENOG4105C3K	feS assembly ATPase SufC
ACAM_1071	ENOG4105BZN	citrate synthase
ACAM_1074	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ACAM_1075	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ACAM_1078	ENOG4105NAA	Cytochrome C oxidase, subunit II
ACAM_1080	ENOG4105K63	Thioredoxin
ACAM_1084	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ACAM_1087	ENOG4105D38	putrescine abc transporter
ACAM_1088	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACAM_1090	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACAM_1091	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACAM_1092	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACAM_1093	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ACAM_1096	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ACAM_1097	ENOG4108UJD	30S ribosomal protein S9
ACAM_1099	ENOG4105CE9	30S ribosomal protein S2
ACAM_1108	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
ACAM_1109	ENOG4105CAS	nag kinase
ACAM_1111	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
ACAM_1112	ENOG4107QI1	Mate efflux family protein
ACAM_1113	ENOG4105CTD	carboxy-peptidase
ACAM_1116	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
ACAM_1119	ENOG4105C26	Dehydrogenase
ACAM_1123	ENOG4105M7V	2'-5' rna ligase
ACAM_1124	ENOG4108IYH	Dna topoisomerase
ACAM_1126	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ACAM_1127	ENOG4105ECY	inositol monophosphatase
ACAM_1131	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ACAM_1137	ENOG4105C9Q	fumarate hydratase class II
ACAM_1144	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ACAM_1147	ENOG4108IUW	ABC transporter
ACAM_1148	ENOG4105C5I	Dehydrogenase
ACAM_1149	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
ACAM_1151	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ACAM_1153	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
ACAM_1154	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACAM_1156	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ACAM_1157	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACAM_1158	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ACAM_1162	ENOG4105XPM	ribosomal protein
ACAM_1163	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACAM_1164	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACAM_1165	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACAM_1177	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ACAM_1178	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACAM_1181	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
ACAM_1184	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
ACAM_1190	ENOG4105E5Q	amino acid AbC transporter
ACAM_1191	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
ACAM_1202	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ACAM_1208	ENOG4108SDH	ABC, transporter
ACAM_1213	ENOG41080HJ	6-phospho 3-hexuloisomerase
ACAM_1226	ENOG4105C4K	Nad synthetase
ACAM_1228	ENOG4105CV8	reductase
ACAM_1229	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACAM_1236	ENOG4105C5B	carbamate kinase
ACAM_1240	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ACAM_1242	ENOG4105VG1	fes assembly suf system protein
ACAM_1244	ENOG4105CEV	competence damage-inducible protein
ACAM_1251	ENOG4105DBV	ornithine carbamoyltransferase
ACAM_1261	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
ACAM_1263	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACAM_1269	ENOG4105G5W	regulator Fur family
ACAM_1274	ENOG4105C45	hydrogenase expression formation protein (HypE)
ACAM_1275	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ACAM_1276	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ACAM_1284	ENOG4108IJ9	(ABC) transporter
ACAM_1285	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACAM_1286	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
ACAM_1287	ENOG4105E2K	Glycosyl transferase (Group 1
ACAM_1289	ENOG4105C28	cystathionine
ACAM_1294	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACAM_1295	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ACAM_1300	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
ACAM_1302	ENOG4105C88	aminopeptidase
ACAM_1305	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
ACAM_1316	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
ACAM_1317	ENOG4108I5U	Uridine phosphorylase
ACAM_1318	ENOG4108RVA	ribokinase
ACAM_1320	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACAM_1327	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACAM_1328	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACAM_1329	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACAM_1331	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
ACAM_1332	ENOG4105DQU	oxidoreductase, subunit beta
ACAM_1334	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ACAM_1339	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACAM_1340	ENOG4105C5F	glutamine synthetase
ACAM_1341	ENOG4107QRT	dEAD DEAH box helicase
ACAM_1344	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
ACAM_1346	ENOG4107QX8	SPFH domain, Band 7 family protein
ACAM_1347	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ACAM_1350	ENOG4108JJB	ABC transporter
ACAM_1354	ENOG4105C1G	acyl-Coa dehydrogenase
ACAM_1357	ENOG4105D22	carbon starvation protein
ACAM_1359	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
ACAM_1360	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACAM_1363	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ACAM_1364	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ACAM_1375	ENOG4107QRT	dEAD DEAH box helicase
ACAM_1377	ENOG4105C5S	asparaginyl-tRNA synthetase
ACAM_1382	ENOG4105HDK	L-asparaginase
ACAM_1383	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
ACAM_1391	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ACAM_1393	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
ACAM_1395	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
ACAM_1405	ENOG4108VX5	3-methyladenine DNA glycosylase
ACAM_1406	ENOG4105CHM	Aminotransferase
ACAM_1409	ENOG4105EG2	ABC transporter, permease
ACAM_1412	ENOG4105DEF	Extracellular solute-binding protein, family 5
ACAM_1413	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACAM_1414	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACAM_1416	ENOG4108JQ7	(ABC) transporter
ACAM_1421	ENOG4108JJB	ABC transporter
ACAM_1422	ENOG4105K63	Thioredoxin
ACAM_1425	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
ACAM_1426	ENOG4105D3R	alkyl hydroperoxide reductase
ACAM_1428	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ACAM_1430	ENOG4105CEY	Amp-dependent synthetase and ligase
ACAM_1434	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
ACAM_1435	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
ACAM_1439	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ACAM_1440	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ACAM_1441	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ACAM_1442	ENOG4105D52	delta-aminolevulinic acid dehydratase
ACAM_1443	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ACAM_1444	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
ACAM_1445	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
ACAM_1452	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACAM_1453	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACAM_1454	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ACAM_1460	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ACAM_1473	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
ACAM_1474	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ACAM_1476	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
ACAM_1477	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ACAM_1478	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
ACAM_1486	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ACAM_1488	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ACAM_1490	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ACAM_1491	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ACAM_1495	ENOG4105CRW	Short chain fatty acid transporter
ACAM_1500	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
ACAM_1501	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACAM_1502	ENOG4105DWF	phosphomethylpyrimidine kinase
ACAM_1504	ENOG4108JJB	ABC transporter
ACAM_1505	ENOG4108JJB	ABC transporter
ACAM_1514	ENOG4107QI1	Mate efflux family protein
ACAM_1516	ENOG4105BZJ	Electron transfer flavoprotein
ACAM_1517	ENOG4105C10	Electron transfer flavoprotein
ACAM_1518	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
ACAM_1519	ENOG4105C5R	Aminotransferase
ACAM_1525	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
ACAM_1529	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
ACAM_1531	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
ACAM_1532	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
ACAM_1535	ENOG4105CAG	UPF0210 protein
ACAM_1538	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ACAM_1539	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ACAM_1543	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ACAM_1544	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ACAM_1549	ENOG4108IAB	Phoh family
ACAM_1550	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ACAM_1553	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
ACAM_1558	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACAM_1566	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACAM_1570	ENOG4105K59	histidine triad (HIT) protein
ACAM_1572	ENOG41081FY	multiple antibiotic resistance (MarC)-related
ACAM_1578	ENOG4105CHR	reductase
ACAM_1580	ENOG4108JQ1	Dehydrogenase
ACAM_1585	ENOG4105KVH	Transcriptional regulator
ACAM_1587	ENOG4105CPC	Aldo Keto reductase
ACAM_1588	ENOG4105C7Z	Conserved Protein
ACAM_1592	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ACAM_1597	ENOG4108K28	Arsenite oxidase, large subunit
ACAM_1602	ENOG4105MRR	Transcriptional regulator (By similarity)
ACAM_1603	ENOG4105C59	p-type ATPase
ACAM_1609	ENOG4105C32	Amino acid ABC transporter (Permease)
ACAM_1611	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
ACAM_1612	ENOG4105C0Z	ABC transporter
ACAM_1613	ENOG4105C0Z	ABC transporter
ACAM_1614	ENOG4105C0Z	ABC transporter
ACAM_1615	ENOG4108IV0	ABC, transporter
ACAM_1616	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACAM_1624	ENOG4105C2J	ABC transporter
ACAM_1627	ENOG4105KHC	sulfurtransferase
ACAM_1631	ENOG4106V2I	dimethylaminohydrolase
ACAM_1633	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ACAM_1634	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ACAM_1636	ENOG4105DB1	molybdopterin oxidoreductase