APE_1917 0bf6474a3b52779a9763ffa035614feb 441 Gene3D G3DSA:3.40.630.10 2 229 3.0E-42 T 23-10-2018 APE_1917 0bf6474a3b52779a9763ffa035614feb 441 SUPERFAMILY SSF53187 4 439 1.23E-52 T 23-10-2018 APE_1917 0bf6474a3b52779a9763ffa035614feb 441 Gene3D G3DSA:3.40.630.10 357 430 3.8E-15 T 23-10-2018 APE_1917 0bf6474a3b52779a9763ffa035614feb 441 Gene3D G3DSA:3.30.70.360 315 356 3.8E-15 T 23-10-2018 APE_1917 0bf6474a3b52779a9763ffa035614feb 441 Pfam PF01546 Peptidase family M20/M25/M40 69 437 2.9E-32 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 APE_1917 0bf6474a3b52779a9763ffa035614feb 441 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 138 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 APE_0981.1 316868f1410a66b85b90b2b570e7e871 202 Gene3D G3DSA:3.40.50.300 5 200 3.0E-50 T 23-10-2018 APE_0981.1 316868f1410a66b85b90b2b570e7e871 202 SMART SM00382 4 154 7.7E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0981.1 316868f1410a66b85b90b2b570e7e871 202 Hamap MF_00234 Adenylate kinase [adkA]. 6 200 47.568 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 APE_0981.1 316868f1410a66b85b90b2b570e7e871 202 Pfam PF13207 AAA domain 11 149 3.6E-32 T 23-10-2018 APE_0981.1 316868f1410a66b85b90b2b570e7e871 202 SUPERFAMILY SSF52540 6 199 1.84E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 PIRSF PIRSF000858 10 551 8.7E-202 T 23-10-2018 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 Reactome: R-HSA-77108 APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 SMART SM00882 305 517 0.0016 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 SMART SM00882 14 262 5.2E-41 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 Gene3D G3DSA:3.40.1080.10 8 285 3.8E-84 T 23-10-2018 APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 Pfam PF01144 Coenzyme A transferase 15 262 2.5E-52 T 23-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 SUPERFAMILY SSF100950 13 278 4.47E-63 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 Gene3D G3DSA:3.40.1080.10 295 550 3.3E-87 T 23-10-2018 APE_2468.1 c2a881c14c287453aeb52842d00c5433 554 SUPERFAMILY SSF100950 296 542 5.16E-61 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_1871.1 a15c44592f4e302219bed7f620ca0b92 133 SUPERFAMILY SSF50249 4 117 3.77E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1871.1 a15c44592f4e302219bed7f620ca0b92 133 Gene3D G3DSA:1.10.12.20 5 50 5.7E-6 T 23-10-2018 APE_1871.1 a15c44592f4e302219bed7f620ca0b92 133 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 112 9.3E-11 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal APE_1871.1 a15c44592f4e302219bed7f620ca0b92 133 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 15 46 1.8E-12 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 Gene3D G3DSA:2.170.190.11 51 134 5.7E-60 T 23-10-2018 APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 Gene3D G3DSA:3.90.105.10 27 167 5.7E-60 T 23-10-2018 APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 SUPERFAMILY SSF63882 6 168 2.75E-36 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 Pfam PF00994 Probable molybdopterin binding domain 174 302 1.2E-10 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 SUPERFAMILY SSF53218 172 310 1.7E-22 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 Gene3D G3DSA:2.40.340.10 315 367 5.7E-60 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 Gene3D G3DSA:3.40.980.10 168 314 5.7E-60 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 SMART SM00852 172 308 9.2E-17 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0177 44f67ebc19b2783679aa0115e0d874d0 386 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 160 2.2E-29 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 462 8.7E-51 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 196 209 3.6E-17 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 5 21 3.6E-17 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 128 142 3.6E-17 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 85 97 - T 23-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 Gene3D G3DSA:3.40.50.150 4 231 1.4E-44 T 23-10-2018 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 SUPERFAMILY SSF53335 4 463 4.51E-64 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 Gene3D G3DSA:3.90.120.10 385 451 7.7E-15 T 23-10-2018 APE_0872.1 ce263ed23fa2865c18d6787cbc1ae73c 469 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 7 462 8.4E-44 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_1109.1 0394c93b21202b21312291c8c8e85b60 387 Pfam PF01950 Fructose-1,6-bisphosphatase 7 366 6.7E-189 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 APE_1109.1 0394c93b21202b21312291c8c8e85b60 387 PIRSF PIRSF015647 5 377 2.2E-193 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 APE_1109.1 0394c93b21202b21312291c8c8e85b60 387 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 8 365 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 APE_1109.1 0394c93b21202b21312291c8c8e85b60 387 SUPERFAMILY SSF111249 7 366 2.75E-179 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 APE_1109.1 0394c93b21202b21312291c8c8e85b60 387 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 366 61.47 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 APE_1472 f5ec61a4d6a60a8fbbf05eb64fdc16cf 309 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 49 196 1.7E-29 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APE_1472 f5ec61a4d6a60a8fbbf05eb64fdc16cf 309 Gene3D G3DSA:3.40.50.970 27 214 5.8E-22 T 23-10-2018 APE_1472 f5ec61a4d6a60a8fbbf05eb64fdc16cf 309 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 200 274 7.6E-20 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal APE_1472 f5ec61a4d6a60a8fbbf05eb64fdc16cf 309 SUPERFAMILY SSF52518 13 273 5.26E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_1472 f5ec61a4d6a60a8fbbf05eb64fdc16cf 309 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 304 4.4E-142 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate APE_1373 b3772a7fce3efaf222956e59579e5feb 453 Pfam PF02308 MgtC family 16 149 4.5E-11 T 23-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 APE_1373 b3772a7fce3efaf222956e59579e5feb 453 Pfam PF13194 Domain of unknown function (DUF4010) 198 417 9.6E-36 T 23-10-2018 IPR025105 Domain of unknown function DUF4010 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 Gene3D G3DSA:1.10.287.10 82 149 5.7E-29 T 23-10-2018 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 ProSitePatterns PS00362 Ribosomal protein S15 signature. 96 126 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 SUPERFAMILY SSF47060 64 140 1.44E-21 T 23-10-2018 IPR009068 S15/NS1, RNA-binding APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 Gene3D G3DSA:1.10.8.1030 34 81 2.7E-18 T 23-10-2018 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 1 147 34.888 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 SMART SM01386 2 58 1.1E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 SMART SM01387 69 147 1.5E-18 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 3 58 3.5E-23 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 88 132 8.0E-4 T 23-10-2018 APE_1139 f0ee2ad08843a27644036a4788da9ddf 150 Pfam PF00312 Ribosomal protein S15 71 146 6.4E-18 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 TIGRFAM TIGR00191 thrB: homoserine kinase 12 291 4.2E-54 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 SUPERFAMILY SSF54211 7 156 2.88E-24 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 PIRSF PIRSF000676 2 313 3.0E-78 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 Hamap MF_00384 Homoserine kinase [thrB]. 8 313 26.792 T 23-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 Gene3D G3DSA:3.30.230.10 2 167 3.8E-34 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 SUPERFAMILY SSF55060 185 294 2.26E-28 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 PRINTS PR00958 Homoserine kinase signature 98 113 3.9E-24 T 23-10-2018 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 PRINTS PR00958 Homoserine kinase signature 179 196 3.9E-24 T 23-10-2018 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 PRINTS PR00958 Homoserine kinase signature 138 151 3.9E-24 T 23-10-2018 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 PRINTS PR00958 Homoserine kinase signature 259 274 3.9E-24 T 23-10-2018 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 PRINTS PR00958 Homoserine kinase signature 13 28 3.9E-24 T 23-10-2018 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 Pfam PF00288 GHMP kinases N terminal domain 85 151 1.7E-11 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 Gene3D G3DSA:3.30.70.890 168 297 3.9E-31 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 91 102 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 APE_2067.1 a159f7337ef1b8a47f98004f8b165dc5 313 Pfam PF08544 GHMP kinases C terminal 215 292 2.8E-11 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain APE_0294.1 a4eab89ff4798c24175cf426c2cd2392 146 SUPERFAMILY SSF49503 50 145 1.71E-17 T 23-10-2018 IPR008972 Cupredoxin APE_0294.1 a4eab89ff4798c24175cf426c2cd2392 146 Gene3D G3DSA:2.60.40.420 34 145 4.6E-17 T 23-10-2018 IPR008972 Cupredoxin APE_0294.1 a4eab89ff4798c24175cf426c2cd2392 146 Pfam PF13473 Cupredoxin-like domain 48 132 3.7E-11 T 23-10-2018 IPR028096 EfeO-type cupredoxin-like domain APE_0917 a09db4a86419dc48bc4a9464ad914aa2 500 Pfam PF13458 Periplasmic binding protein 35 357 7.8E-40 T 23-10-2018 IPR028081 Leucine-binding protein domain APE_0917 a09db4a86419dc48bc4a9464ad914aa2 500 PRINTS PR01176 Metabotropic gamma-aminobutyric acid type B receptor signature 328 340 9.1E-5 T 23-10-2018 APE_0917 a09db4a86419dc48bc4a9464ad914aa2 500 PRINTS PR01176 Metabotropic gamma-aminobutyric acid type B receptor signature 52 68 9.1E-5 T 23-10-2018 APE_0917 a09db4a86419dc48bc4a9464ad914aa2 500 Gene3D G3DSA:3.40.50.2300 42 355 1.5E-53 T 23-10-2018 APE_0917 a09db4a86419dc48bc4a9464ad914aa2 500 Gene3D G3DSA:3.40.50.2300 155 293 1.5E-53 T 23-10-2018 APE_0917 a09db4a86419dc48bc4a9464ad914aa2 500 SUPERFAMILY SSF53822 28 416 6.54E-60 T 23-10-2018 IPR028082 Periplasmic binding protein-like I APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 SUPERFAMILY SSF50156 207 300 2.89E-14 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 Pfam PF13180 PDZ domain 208 267 2.4E-8 T 23-10-2018 IPR001478 PDZ domain GO:0005515 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 Pfam PF02163 Peptidase family M50 120 341 2.7E-10 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 Gene3D G3DSA:2.30.42.10 205 275 5.3E-15 T 23-10-2018 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 SMART SM00228 194 270 2.2E-6 T 23-10-2018 IPR001478 PDZ domain GO:0005515 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 105 124 7.9E-17 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 160 172 7.9E-17 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 128 142 7.9E-17 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APE_0209.1 a99ed5c00e2644a62f65b3176fba1c7f 380 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 144 159 7.9E-17 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APE_2094.1 4198d0ee064e2cef25d4760c78c9e54a 197 Gene3D G3DSA:3.40.50.300 1 188 1.5E-23 T 23-10-2018 APE_2094.1 4198d0ee064e2cef25d4760c78c9e54a 197 SUPERFAMILY SSF52540 2 161 3.4E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2094.1 4198d0ee064e2cef25d4760c78c9e54a 197 Pfam PF13238 AAA domain 4 124 3.7E-10 T 23-10-2018 APE_2443.1 72c518b18872236f02fe3509a489163e 322 Pfam PF00382 Transcription factor TFIIB repeat 127 189 3.0E-15 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 APE_2443.1 72c518b18872236f02fe3509a489163e 322 Pfam PF00382 Transcription factor TFIIB repeat 229 296 3.0E-16 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 APE_2443.1 72c518b18872236f02fe3509a489163e 322 SUPERFAMILY SSF47954 119 219 2.88E-21 T 23-10-2018 IPR036915 Cyclin-like superfamily APE_2443.1 72c518b18872236f02fe3509a489163e 322 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 258 273 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 APE_2443.1 72c518b18872236f02fe3509a489163e 322 SUPERFAMILY SSF47954 221 310 8.16E-26 T 23-10-2018 IPR036915 Cyclin-like superfamily APE_2443.1 72c518b18872236f02fe3509a489163e 322 Gene3D G3DSA:1.10.472.10 222 316 6.2E-23 T 23-10-2018 APE_2443.1 72c518b18872236f02fe3509a489163e 322 Gene3D G3DSA:1.10.472.170 19 211 5.0E-35 T 23-10-2018 APE_2443.1 72c518b18872236f02fe3509a489163e 322 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 10 311 36.3 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea APE_2443.1 72c518b18872236f02fe3509a489163e 322 SMART SM00385 125 211 6.4E-7 T 23-10-2018 IPR013763 Cyclin-like APE_2443.1 72c518b18872236f02fe3509a489163e 322 SMART SM00385 224 305 6.7E-11 T 23-10-2018 IPR013763 Cyclin-like APE_2443.1 72c518b18872236f02fe3509a489163e 322 PRINTS PR00685 Transcription initiation factor IIB signature 225 243 1.6E-19 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_2443.1 72c518b18872236f02fe3509a489163e 322 PRINTS PR00685 Transcription initiation factor IIB signature 259 275 1.6E-19 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_2443.1 72c518b18872236f02fe3509a489163e 322 PRINTS PR00685 Transcription initiation factor IIB signature 28 48 1.6E-19 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_2443.1 72c518b18872236f02fe3509a489163e 322 PRINTS PR00685 Transcription initiation factor IIB signature 167 186 1.6E-19 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_2443.1 72c518b18872236f02fe3509a489163e 322 PRINTS PR00685 Transcription initiation factor IIB signature 291 305 1.6E-19 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_2443.1 72c518b18872236f02fe3509a489163e 322 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 159 174 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 APE_0900.1 0af5431e460f0a639f214c594601f7ff 128 Gene3D G3DSA:3.40.630.30 9 102 1.2E-20 T 23-10-2018 APE_0900.1 0af5431e460f0a639f214c594601f7ff 128 Pfam PF14542 GCN5-related N-acetyl-transferase 24 92 1.4E-20 T 23-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase APE_0900.1 0af5431e460f0a639f214c594601f7ff 128 SUPERFAMILY SSF55729 16 97 2.23E-21 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_2448 6aa09b6c4f6248a9e3527edfd4429c72 287 PIRSF PIRSF005956 1 283 7.2E-99 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family APE_2448 6aa09b6c4f6248a9e3527edfd4429c72 287 Pfam PF03437 BtpA family 6 278 1.3E-112 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family APE_2448 6aa09b6c4f6248a9e3527edfd4429c72 287 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 40 216 2.0E-96 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family APE_2448 6aa09b6c4f6248a9e3527edfd4429c72 287 SUPERFAMILY SSF51366 45 270 6.83E-17 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_2448 6aa09b6c4f6248a9e3527edfd4429c72 287 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 8 280 1.1E-60 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SUPERFAMILY SSF52540 9 296 3.88E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:3.40.50.300 316 486 5.4E-22 T 23-10-2018 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:3.40.50.300 502 613 2.7E-14 T 23-10-2018 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SMART SM00487 81 323 1.3E-19 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SMART SM00493 618 773 3.1E-23 T 23-10-2018 IPR006171 TOPRIM domain APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:3.40.50.300 65 313 8.2E-67 T 23-10-2018 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Pfam PF01131 DNA topoisomerase 799 1189 9.5E-81 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SUPERFAMILY SSF52540 320 612 8.87E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 833 851 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 938 947 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1019 1035 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1113 1127 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 747 760 1.4E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SMART SM00436 774 861 4.8E-29 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:1.10.460.10 802 1192 1.1E-127 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:1.10.290.10 906 1030 1.1E-127 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SMART SM00437 896 1152 3.9E-72 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SMART SM00382 98 374 1.9E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:2.60.510.20 855 1097 1.1E-127 T 23-10-2018 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Gene3D G3DSA:3.40.50.140 614 796 6.4E-31 T 23-10-2018 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 TIGRFAM TIGR01054 rgy: reverse gyrase 5 1198 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 SUPERFAMILY SSF56712 616 1198 1.01E-131 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Pfam PF00270 DEAD/DEAH box helicase 88 224 3.2E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Pfam PF01751 Toprim domain 620 783 1.0E-21 T 23-10-2018 IPR006171 TOPRIM domain APE_1376.1 578b8badafbc3d3d5ef0eec2052034e3 1215 Hamap MF_01125 Reverse gyrase [rgy]. 4 1200 63.892 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 SUPERFAMILY SSF53223 3 98 1.84E-20 T 23-10-2018 APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 Gene3D G3DSA:3.40.50.720 99 242 3.3E-66 T 23-10-2018 APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 SUPERFAMILY SSF51735 99 260 1.97E-33 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 85 3.6E-16 T 23-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 266 26.458 T 23-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 Gene3D G3DSA:3.40.50.10860 6 255 3.3E-66 T 23-10-2018 APE_0574.1 e9f932c40164fcbeb2ef2f9cfcf54627 273 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 117 188 1.1E-5 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 Pfam PF00005 ABC transporter 52 203 3.3E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 Gene3D G3DSA:3.40.50.300 27 343 1.7E-96 T 23-10-2018 APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 ProSitePatterns PS00211 ABC transporters family signature. 175 189 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 254 321 1.4E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 SMART SM00382 61 252 4.5E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 SUPERFAMILY SSF52540 28 273 2.44E-74 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1402.1 d22d4df7e06075ece17fc23c692f9998 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 252 339 3.1E-29 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_2068 e14ae6c20ae5373574a3dad4916452dd 389 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 386 7.9E-99 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APE_2068 e14ae6c20ae5373574a3dad4916452dd 389 Gene3D G3DSA:3.90.1150.10 253 389 9.4E-49 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2068 e14ae6c20ae5373574a3dad4916452dd 389 PIRSF PIRSF001434 5 389 1.1E-121 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APE_2068 e14ae6c20ae5373574a3dad4916452dd 389 Gene3D G3DSA:3.40.640.10 2 252 4.8E-54 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2068 e14ae6c20ae5373574a3dad4916452dd 389 SUPERFAMILY SSF53383 48 387 5.1E-84 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2182 e0160739b40aea31d8972d191124542b 251 SUPERFAMILY SSF55979 2 105 1.96E-19 T 23-10-2018 APE_2182 e0160739b40aea31d8972d191124542b 251 Gene3D G3DSA:3.70.10.10 1 244 3.5E-66 T 23-10-2018 APE_2182 e0160739b40aea31d8972d191124542b 251 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 34 57 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_2182 e0160739b40aea31d8972d191124542b 251 SUPERFAMILY SSF55979 130 248 1.81E-21 T 23-10-2018 APE_2182 e0160739b40aea31d8972d191124542b 251 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 7 103 2.5E-5 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_2182 e0160739b40aea31d8972d191124542b 251 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 2 249 27.089 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_1346.1 bc0165e855dd10978187b1d38371c905 656 Gene3D G3DSA:3.40.50.12780 72 526 3.5E-88 T 23-10-2018 APE_1346.1 bc0165e855dd10978187b1d38371c905 656 Gene3D G3DSA:3.30.300.30 527 654 3.1E-27 T 23-10-2018 APE_1346.1 bc0165e855dd10978187b1d38371c905 656 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 616 1.6E-21 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APE_1346.1 bc0165e855dd10978187b1d38371c905 656 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 23-10-2018 IPR020845 AMP-binding, conserved site APE_1346.1 bc0165e855dd10978187b1d38371c905 656 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 30 87 6.5E-12 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 APE_1346.1 bc0165e855dd10978187b1d38371c905 656 Pfam PF00501 AMP-binding enzyme 97 530 1.0E-76 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_1346.1 bc0165e855dd10978187b1d38371c905 656 SUPERFAMILY SSF56801 24 645 3.92E-152 T 23-10-2018 APE_0249.1 16cb8ce9625c2953c69d94975db1b31f 382 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 69 376 1.1E-90 T 23-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 APE_0249.1 16cb8ce9625c2953c69d94975db1b31f 382 SMART SM00729 73 284 7.7E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_0249.1 16cb8ce9625c2953c69d94975db1b31f 382 Pfam PF04055 Radical SAM superfamily 78 250 1.4E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_0249.1 16cb8ce9625c2953c69d94975db1b31f 382 SUPERFAMILY SSF102114 51 371 8.76E-48 T 23-10-2018 APE_0249.1 16cb8ce9625c2953c69d94975db1b31f 382 Gene3D G3DSA:3.20.20.70 24 345 1.3E-52 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0249.1 16cb8ce9625c2953c69d94975db1b31f 382 PIRSF PIRSF004762 12 381 1.2E-94 T 23-10-2018 APE_1275 b25212166b599e342ed6026a5aa627af 467 Gene3D G3DSA:3.90.1150.10 12 459 2.5E-185 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_1275 b25212166b599e342ed6026a5aa627af 467 PIRSF PIRSF001386 6 465 3.9E-195 T 23-10-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 APE_1275 b25212166b599e342ed6026a5aa627af 467 ProSitePatterns PS00853 Beta-eliminating lyases pyridoxal-phosphate attachment site. 253 271 - T 23-10-2018 IPR018176 Tryptophanase, conserved site KEGG: 00380+4.1.99.1 APE_1275 b25212166b599e342ed6026a5aa627af 467 Pfam PF01212 Beta-eliminating lyase 52 427 9.1E-86 T 23-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 APE_1275 b25212166b599e342ed6026a5aa627af 467 Hamap MF_00544 Tryptophanase [tnaA]. 7 464 98.643 T 23-10-2018 IPR013440 Tryptophanase GO:0006568|GO:0009034 KEGG: 00380+4.1.99.1 APE_1275 b25212166b599e342ed6026a5aa627af 467 Gene3D G3DSA:3.40.640.10 64 316 2.5E-185 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1275 b25212166b599e342ed6026a5aa627af 467 SUPERFAMILY SSF53383 8 464 9.49E-116 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_0267 c48bee5955bf29fc6390d6a9ab277fea 143 SMART SM00116 22 70 1.8E-10 T 23-10-2018 IPR000644 CBS domain APE_0267 c48bee5955bf29fc6390d6a9ab277fea 143 SMART SM00116 87 135 2.7E-11 T 23-10-2018 IPR000644 CBS domain APE_0267 c48bee5955bf29fc6390d6a9ab277fea 143 SUPERFAMILY SSF54631 13 132 3.54E-37 T 23-10-2018 APE_0267 c48bee5955bf29fc6390d6a9ab277fea 143 Pfam PF00571 CBS domain 80 132 3.0E-16 T 23-10-2018 IPR000644 CBS domain APE_0267 c48bee5955bf29fc6390d6a9ab277fea 143 Pfam PF00571 CBS domain 16 70 1.9E-13 T 23-10-2018 IPR000644 CBS domain APE_0267 c48bee5955bf29fc6390d6a9ab277fea 143 Gene3D G3DSA:3.10.580.10 8 141 2.8E-39 T 23-10-2018 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 Gene3D G3DSA:2.40.110.10 130 246 1.3E-39 T 23-10-2018 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 SUPERFAMILY SSF56645 10 250 5.76E-77 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 390 7.1E-48 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 PIRSF PIRSF016578 12 394 1.2E-22 T 23-10-2018 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 SUPERFAMILY SSF47203 239 393 4.35E-57 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 229 4.6E-23 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 Gene3D G3DSA:1.10.540.10 4 128 1.4E-39 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 Gene3D G3DSA:1.20.140.10 247 396 7.2E-54 T 23-10-2018 APE_2158.1 4598c10ea619b26a9cb885f3393b961a 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 16 126 1.5E-33 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 APE_0314.1 d4102232e32438d2c6f29019882e4e0f 276 SUPERFAMILY SSF63992 4 274 2.48E-80 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily APE_0314.1 d4102232e32438d2c6f29019882e4e0f 276 PIRSF PIRSF015853 3 276 5.6E-97 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase APE_0314.1 d4102232e32438d2c6f29019882e4e0f 276 Gene3D G3DSA:3.40.50.10780 4 218 3.6E-63 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal APE_0314.1 d4102232e32438d2c6f29019882e4e0f 276 Pfam PF04951 D-aminopeptidase 4 264 1.7E-74 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase APE_0314.1 d4102232e32438d2c6f29019882e4e0f 276 Gene3D G3DSA:3.30.1360.130 119 263 3.6E-63 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Gene3D G3DSA:1.10.3380.30 423 643 5.6E-47 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 12 702 28.335 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SUPERFAMILY SSF158702 500 702 1.1E-49 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SMART SM00490 294 384 1.4E-19 T 23-10-2018 IPR001650 Helicase, C-terminal APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Pfam PF00270 DEAD/DEAH box helicase 32 184 3.4E-19 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Pfam PF00271 Helicase conserved C-terminal domain 300 384 8.4E-11 T 23-10-2018 IPR001650 Helicase, C-terminal APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SMART SM00487 24 211 1.3E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SUPERFAMILY SSF46785 416 499 3.02E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SUPERFAMILY SSF52540 41 394 2.36E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SMART SM00382 42 276 3.8E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Gene3D G3DSA:3.40.50.300 207 409 9.3E-51 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Pfam PF14520 Helix-hairpin-helix domain 648 701 2.1E-10 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Gene3D G3DSA:1.10.150.20 645 701 1.0E-21 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 Gene3D G3DSA:3.40.50.300 14 204 1.9E-54 T 23-10-2018 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SMART SM00278 647 666 39.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APE_0191.1 105c977c12e12ded012cd06696b5da6e 735 SMART SM00278 680 699 0.055 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APE_0534.1 f4698a5b3d624330332b05dab0f12507 270 SUPERFAMILY SSF81345 14 262 3.53E-6 T 23-10-2018 IPR037294 ABC transporter, BtuC-like APE_0534.1 f4698a5b3d624330332b05dab0f12507 270 Pfam PF00950 ABC 3 transport family 18 262 2.0E-14 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 APE_1209c.1 70a3ea059a6ba2b8bdca608438f66c82 73 Pfam PF01954 Protein of unknown function DUF104 1 50 6.4E-17 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_1209c.1 70a3ea059a6ba2b8bdca608438f66c82 73 SUPERFAMILY SSF141694 1 40 2.88E-12 T 23-10-2018 APE_1209c.1 70a3ea059a6ba2b8bdca608438f66c82 73 Gene3D G3DSA:4.10.1150.10 1 70 1.2E-9 T 23-10-2018 IPR024069 AF2212-like domain superfamily APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 229 244 2.8E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 78 97 2.8E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 24 38 2.8E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 163 183 2.8E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 142 159 2.8E-29 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 Gene3D G3DSA:3.40.50.1010 1 223 4.5E-84 T 23-10-2018 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 350 142.908 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 SMART SM00485 1 104 1.8E-48 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 ProSitePatterns PS00841 XPG protein signature 1. 76 90 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 349 1.3E-152 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 SUPERFAMILY SSF47807 224 349 3.44E-27 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 Pfam PF00867 XPG I-region 144 239 8.2E-27 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 SMART SM00279 226 260 5.4E-6 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 SUPERFAMILY SSF88723 5 239 3.27E-64 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 Pfam PF00752 XPG N-terminal domain 7 104 2.5E-21 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 Gene3D G3DSA:1.10.150.20 224 289 2.7E-16 T 23-10-2018 APE_0115.1 83957dfbda87887bd8bb4fcbc39be715 350 SMART SM00484 143 224 1.5E-35 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 APE_1169.1 779202974c03b4aceabcec76553e5077 251 PIRSF PIRSF000883 1 242 7.9E-57 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 APE_1169.1 779202974c03b4aceabcec76553e5077 251 Gene3D G3DSA:3.60.21.10 1 238 3.7E-60 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_1169.1 779202974c03b4aceabcec76553e5077 251 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 203 7.4E-25 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 APE_1169.1 779202974c03b4aceabcec76553e5077 251 SUPERFAMILY SSF56300 2 236 9.21E-65 T 23-10-2018 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 SMART SM00090 65 294 4.2E-46 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 Gene3D G3DSA:1.10.510.10 194 299 3.0E-22 T 23-10-2018 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 Gene3D G3DSA:1.10.10.10 3 92 1.1E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1602.1 e592a363180543df95c8662f3eba73d1 301 Pfam PF09202 Rio2, N-terminal 10 90 3.0E-21 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 226 237 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 Gene3D G3DSA:3.30.200.20 93 192 2.7E-28 T 23-10-2018 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 Pfam PF01163 RIO1 family 107 283 1.4E-53 T 23-10-2018 APE_1602.1 e592a363180543df95c8662f3eba73d1 301 SUPERFAMILY SSF46785 4 91 2.88E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1602.1 e592a363180543df95c8662f3eba73d1 301 SUPERFAMILY SSF56112 96 275 4.71E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 272 431 6.3E-40 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 Gene3D G3DSA:1.20.140.10 273 452 4.4E-40 T 23-10-2018 APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 SUPERFAMILY SSF47203 272 435 3.06E-41 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 SUPERFAMILY SSF56645 82 278 1.83E-35 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 Gene3D G3DSA:2.40.110.20 121 271 6.6E-32 T 23-10-2018 APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 262 4.7E-17 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APE_0385.1 ec5debc99f373c1247424aaf26274f5a 543 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 390 409 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 ProSitePatterns PS01047 Heavy-metal-associated domain. 25 54 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 PRINTS PR00946 Mercury scavenger protein signature 17 28 3.3E-8 T 23-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 PRINTS PR00946 Mercury scavenger protein signature 59 73 3.3E-8 T 23-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 PRINTS PR00946 Mercury scavenger protein signature 44 59 3.3E-8 T 23-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 PRINTS PR00946 Mercury scavenger protein signature 28 44 3.3E-8 T 23-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 Pfam PF00403 Heavy-metal-associated domain 25 75 4.8E-12 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 Gene3D G3DSA:3.30.70.100 15 80 7.5E-15 T 23-10-2018 APE_0009.1 8e1255893c0287e318dd6425557fbd9e 94 SUPERFAMILY SSF55008 14 75 1.01E-16 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 APE_0805 179920905dcce92a04b74875a1f86a5d 362 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 22 291 48.655 T 23-10-2018 IPR033686 Tyrosine recombinase XerA APE_0805 179920905dcce92a04b74875a1f86a5d 362 Gene3D G3DSA:1.10.443.10 124 287 5.7E-46 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APE_0805 179920905dcce92a04b74875a1f86a5d 362 Gene3D G3DSA:1.10.150.130 15 115 1.1E-6 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal APE_0805 179920905dcce92a04b74875a1f86a5d 362 SUPERFAMILY SSF56349 21 287 7.65E-52 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APE_0805 179920905dcce92a04b74875a1f86a5d 362 Pfam PF00589 Phage integrase family 128 279 3.3E-33 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APE_2424 e100cefb407c7e20246356242456d259 220 Pfam PF01997 Translin family 98 191 1.0E-6 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 APE_2424 e100cefb407c7e20246356242456d259 220 SUPERFAMILY SSF74784 16 204 7.06E-34 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 APE_2424 e100cefb407c7e20246356242456d259 220 Gene3D G3DSA:1.20.58.2140 14 210 9.4E-58 T 23-10-2018 APE_0162 c699affa83834262e5f99dda3afc089b 263 SUPERFAMILY SSF55979 20 132 6.73E-24 T 23-10-2018 APE_0162 c699affa83834262e5f99dda3afc089b 263 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 196 260 7.0E-5 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0162 c699affa83834262e5f99dda3afc089b 263 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 21 118 1.1E-9 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0162 c699affa83834262e5f99dda3afc089b 263 SUPERFAMILY SSF55979 142 260 1.73E-22 T 23-10-2018 APE_0162 c699affa83834262e5f99dda3afc089b 263 Gene3D G3DSA:3.70.10.10 15 257 5.1E-56 T 23-10-2018 APE_0162 c699affa83834262e5f99dda3afc089b 263 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 15 262 29.561 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0162 c699affa83834262e5f99dda3afc089b 263 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 47 70 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_2356.1 92c158fcda0103062ff1dfdefc5b4c37 130 SUPERFAMILY SSF141322 60 126 1.57E-8 T 23-10-2018 APE_2356.1 92c158fcda0103062ff1dfdefc5b4c37 130 Gene3D G3DSA:2.40.50.140 57 129 3.4E-8 T 23-10-2018 APE_2356.1 92c158fcda0103062ff1dfdefc5b4c37 130 Pfam PF01957 NfeD-like C-terminal, partner-binding 11 127 1.4E-8 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 PIRSF PIRSF000505 7 422 3.1E-119 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 SUPERFAMILY SSF55205 10 419 7.03E-100 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 ProSitePatterns PS00885 EPSP synthase signature 2. 330 348 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 14 412 9.4E-89 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 ProSitePatterns PS00104 EPSP synthase signature 1. 89 103 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 19 417 3.6E-130 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 Gene3D G3DSA:3.65.10.10 27 236 2.5E-108 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 Gene3D G3DSA:3.65.10.10 19 408 2.5E-108 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APE_0569 a32f9d40fbeb4cd93dc4f2f122e2755d 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 15 418 31.369 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APE_1604 8cd11eb11df09492e2caca9318dfff62 538 Gene3D G3DSA:3.40.50.880 288 537 1.1E-95 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_1604 8cd11eb11df09492e2caca9318dfff62 538 SUPERFAMILY SSF52317 291 535 3.11E-74 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_1604 8cd11eb11df09492e2caca9318dfff62 538 Hamap MF_01227 CTP synthase [pyrG]. 4 537 49.984 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 APE_1604 8cd11eb11df09492e2caca9318dfff62 538 SUPERFAMILY SSF52540 4 267 2.13E-113 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1604 8cd11eb11df09492e2caca9318dfff62 538 Gene3D G3DSA:3.40.50.300 1 287 5.1E-126 T 23-10-2018 APE_1604 8cd11eb11df09492e2caca9318dfff62 538 Pfam PF06418 CTP synthase N-terminus 5 267 5.7E-119 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 APE_1604 8cd11eb11df09492e2caca9318dfff62 538 Pfam PF00117 Glutamine amidotransferase class-I 304 531 4.0E-47 T 23-10-2018 IPR017926 Glutamine amidotransferase APE_1604 8cd11eb11df09492e2caca9318dfff62 538 TIGRFAM TIGR00337 PyrG: CTP synthase 5 532 1.8E-221 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 APE_2220.1 3f21a05ff9b58034000656cc1a46902b 298 Pfam PF07728 AAA domain (dynein-related subfamily) 47 198 1.1E-10 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 APE_2220.1 3f21a05ff9b58034000656cc1a46902b 298 Gene3D G3DSA:3.40.50.300 29 217 6.9E-31 T 23-10-2018 APE_2220.1 3f21a05ff9b58034000656cc1a46902b 298 SMART SM00382 43 205 1.7E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2220.1 3f21a05ff9b58034000656cc1a46902b 298 SUPERFAMILY SSF52540 25 280 5.49E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Pfam PF00623 RNA polymerase Rpb1, domain 2 322 490 2.8E-69 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Gene3D G3DSA:3.30.1490.180 355 421 2.4E-76 T 23-10-2018 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Pfam PF04997 RNA polymerase Rpb1, domain 1 14 320 7.9E-78 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Gene3D G3DSA:1.10.274.100 496 651 1.6E-93 T 23-10-2018 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Gene3D G3DSA:1.10.132.30 652 798 1.6E-93 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Pfam PF04983 RNA polymerase Rpb1, domain 3 493 659 2.2E-38 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 12 880 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 SMART SM00663 212 518 1.9E-186 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 SUPERFAMILY SSF64484 12 873 1.95E-295 T 23-10-2018 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Gene3D G3DSA:2.40.40.20 312 485 2.4E-76 T 23-10-2018 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Pfam PF04998 RNA polymerase Rpb1, domain 5 797 862 1.4E-26 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Gene3D G3DSA:2.20.25.410 836 888 1.2E-22 T 23-10-2018 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Gene3D G3DSA:1.20.120.1280 6 121 6.9E-22 T 23-10-2018 APE_1853.1 9151631d4b706fdf6307ab635a7f6f8d 891 Pfam PF05000 RNA polymerase Rpb1, domain 4 684 790 3.3E-30 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1279.1 f2bc589162b88dc45159571a0fb5a1c7 220 Gene3D G3DSA:3.40.430.10 1 217 8.8E-52 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 APE_1279.1 f2bc589162b88dc45159571a0fb5a1c7 220 SUPERFAMILY SSF53597 3 212 3.4E-49 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 APE_1279.1 f2bc589162b88dc45159571a0fb5a1c7 220 Pfam PF01872 RibD C-terminal domain 4 199 2.7E-38 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SMART SM00436 816 930 7.0E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SUPERFAMILY SSF52540 345 633 2.76E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SMART SM00382 104 332 0.0067 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SMART SM00487 87 337 8.0E-19 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:1.10.460.10 846 1316 9.3E-113 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:3.40.50.300 70 331 1.6E-77 T 23-10-2018 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 TIGRFAM TIGR01054 rgy: reverse gyrase 8 1322 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1107 1123 3.5E-29 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1212 1226 3.5E-29 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1023 1032 3.5E-29 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 789 802 3.5E-29 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 903 921 3.5E-29 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:2.60.510.20 925 1196 9.3E-113 T 23-10-2018 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:3.40.50.300 334 514 6.1E-30 T 23-10-2018 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:3.40.50.300 549 636 1.9E-13 T 23-10-2018 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Hamap MF_01125 Reverse gyrase [rgy]. 7 1323 67.55 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Pfam PF00270 DEAD/DEAH box helicase 95 231 2.6E-10 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:2.20.20.30 676 764 3.0E-12 T 23-10-2018 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SMART SM00493 647 815 8.3E-24 T 23-10-2018 IPR006171 TOPRIM domain APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SMART SM00437 981 1256 4.6E-80 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:3.40.50.140 765 845 5.7E-21 T 23-10-2018 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SUPERFAMILY SSF52540 79 241 2.7E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Gene3D G3DSA:1.10.290.10 991 1118 9.3E-113 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Pfam PF01131 DNA topoisomerase 841 1312 2.5E-66 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SMART SM00490 381 575 4.9E-6 T 23-10-2018 IPR001650 Helicase, C-terminal APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 Pfam PF01751 Toprim domain 649 825 3.7E-20 T 23-10-2018 IPR006171 TOPRIM domain APE_1340.1 3a1084faee3bbc95dbdf5a76fce58d8d 1370 SUPERFAMILY SSF56712 643 1321 8.76E-125 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 SUPERFAMILY SSF52922 522 638 2.75E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 251 497 5.7E-56 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 Gene3D G3DSA:3.40.50.970 232 436 1.3E-66 T 23-10-2018 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 Gene3D G3DSA:3.40.50.920 515 631 2.0E-28 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 SUPERFAMILY SSF52518 238 507 2.21E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 SUPERFAMILY SSF53323 5 258 4.58E-28 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 4 623 1.9E-167 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 215 8.9E-43 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 APE_1473.1 d1ac5011ea7efee1dfd4e6350f6136d7 642 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 527 614 9.4E-11 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II APE_2418.1 adbc9d8147811c0ced68bbd2e96a3736 280 SUPERFAMILY SSF52402 3 263 6.98E-63 T 23-10-2018 APE_2418.1 adbc9d8147811c0ced68bbd2e96a3736 280 SMART SM00893 24 219 4.5E-51 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_2418.1 adbc9d8147811c0ced68bbd2e96a3736 280 Pfam PF01012 Electron transfer flavoprotein domain 24 198 5.2E-42 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_2418.1 adbc9d8147811c0ced68bbd2e96a3736 280 PIRSF PIRSF000090 3 269 1.8E-83 T 23-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 APE_2418.1 adbc9d8147811c0ced68bbd2e96a3736 280 Gene3D G3DSA:3.40.50.620 3 267 1.5E-73 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0443.1 f8d20ac4eb725427c8fc68589089f6c1 99 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 18 49 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 APE_0443.1 f8d20ac4eb725427c8fc68589089f6c1 99 SUPERFAMILY SSF55257 4 95 4.55E-21 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_0443.1 f8d20ac4eb725427c8fc68589089f6c1 99 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 2 88 17.737 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_0443.1 f8d20ac4eb725427c8fc68589089f6c1 99 Gene3D G3DSA:3.30.1360.10 3 91 2.1E-15 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_0443.1 f8d20ac4eb725427c8fc68589089f6c1 99 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 15 86 3.0E-14 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 APE_1156.1 c66eb7014035b24cac806ec1f14376bc 352 Pfam PF02926 THUMP domain 23 148 6.0E-28 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_1156.1 c66eb7014035b24cac806ec1f14376bc 352 Gene3D G3DSA:3.30.2130.30 1 149 8.1E-24 T 23-10-2018 APE_1156.1 c66eb7014035b24cac806ec1f14376bc 352 SUPERFAMILY SSF75217 190 333 1.83E-17 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_1156.1 c66eb7014035b24cac806ec1f14376bc 352 SUPERFAMILY SSF143437 6 147 3.49E-20 T 23-10-2018 APE_1156.1 c66eb7014035b24cac806ec1f14376bc 352 SMART SM00981 59 149 3.6E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_1156.1 c66eb7014035b24cac806ec1f14376bc 352 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 340 4.6E-79 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP APE_1458 6c028a970d5e1f21839f8111877707ee 461 TIGRFAM TIGR02053 MerA: mercury(II) reductase 6 460 4.8E-191 T 23-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PIRSF PIRSF000350 2 460 2.2E-96 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 APE_1458 6c028a970d5e1f21839f8111877707ee 461 Gene3D G3DSA:3.30.390.30 336 461 2.9E-39 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APE_1458 6c028a970d5e1f21839f8111877707ee 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 APE_1458 6c028a970d5e1f21839f8111877707ee 461 SUPERFAMILY SSF51905 5 356 2.65E-51 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1458 6c028a970d5e1f21839f8111877707ee 461 Gene3D G3DSA:3.50.50.60 6 323 2.6E-77 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1458 6c028a970d5e1f21839f8111877707ee 461 Gene3D G3DSA:3.50.50.60 135 262 2.6E-77 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.3E-21 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 141 1.3E-21 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 271 1.3E-21 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.3E-21 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.3E-21 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 SUPERFAMILY SSF55424 333 459 1.36E-36 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APE_1458 6c028a970d5e1f21839f8111877707ee 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 445 6.9E-33 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 256 270 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 126 135 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 413 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 440 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.2E-54 T 23-10-2018 APE_1458 6c028a970d5e1f21839f8111877707ee 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 318 1.8E-51 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_1228.1 36f353a41e69a0d9aea70c1192f942fd 243 Gene3D G3DSA:3.30.70.1900 127 242 4.9E-11 T 23-10-2018 APE_1228.1 36f353a41e69a0d9aea70c1192f942fd 243 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 42 238 2.9E-17 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 APE_1228.1 36f353a41e69a0d9aea70c1192f942fd 243 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 130 237 5.9E-11 T 23-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal APE_2081.1 b91ed68aa7c5491d3d0fcd6372c05661 372 Gene3D G3DSA:3.40.1830.10 2 165 3.9E-13 T 23-10-2018 IPR035097 Peptidase M29, N-terminal APE_2081.1 b91ed68aa7c5491d3d0fcd6372c05661 372 Pfam PF02073 Thermophilic metalloprotease (M29) 9 367 1.7E-97 T 23-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 APE_2081.1 b91ed68aa7c5491d3d0fcd6372c05661 372 SUPERFAMILY SSF144052 9 368 9.81E-109 T 23-10-2018 APE_1832a.1 fcce8b9148dd4fb4fe17f14201030399 94 Pfam PF01918 Alba 9 70 2.4E-17 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 APE_1832a.1 fcce8b9148dd4fb4fe17f14201030399 94 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 3 93 23.179 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 APE_1832a.1 fcce8b9148dd4fb4fe17f14201030399 94 PIRSF PIRSF028732 5 94 6.1E-37 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 APE_1832a.1 fcce8b9148dd4fb4fe17f14201030399 94 Gene3D G3DSA:3.30.110.20 6 93 2.7E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 APE_1832a.1 fcce8b9148dd4fb4fe17f14201030399 94 SUPERFAMILY SSF82704 8 93 7.06E-22 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 APE_1832a.1 fcce8b9148dd4fb4fe17f14201030399 94 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 12 93 1.0E-39 T 23-10-2018 APE_0213.1 a48450a79cb14bf86aa25f0d3170a18c 230 Pfam PF01909 Nucleotidyltransferase domain 18 64 5.5E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 APE_0213.1 a48450a79cb14bf86aa25f0d3170a18c 230 SUPERFAMILY SSF81301 22 72 6.27E-10 T 23-10-2018 APE_0213.1 a48450a79cb14bf86aa25f0d3170a18c 230 Gene3D G3DSA:3.30.460.10 12 75 5.3E-6 T 23-10-2018 APE_0213.1 a48450a79cb14bf86aa25f0d3170a18c 230 PIRSF PIRSF005928 1 229 8.4E-104 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase APE_1602a 8e35bf7f60e31e260676ea378f2e53e5 87 SMART SM00418 9 87 3.5E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_1602a 8e35bf7f60e31e260676ea378f2e53e5 87 Pfam PF01022 Bacterial regulatory protein, arsR family 16 60 7.6E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_1602a 8e35bf7f60e31e260676ea378f2e53e5 87 Gene3D G3DSA:1.10.10.10 5 85 3.4E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1602a 8e35bf7f60e31e260676ea378f2e53e5 87 SUPERFAMILY SSF46785 7 85 1.88E-20 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0722a f3f710c6a74d68a375e90ae7feebedfa 91 SUPERFAMILY SSF46785 8 87 3.51E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0722a f3f710c6a74d68a375e90ae7feebedfa 91 Gene3D G3DSA:1.10.10.10 4 87 3.9E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1419.1 c3c907f3f164498f797994fcd451aae1 186 SUPERFAMILY SSF54862 44 146 3.68E-22 T 23-10-2018 APE_1419.1 c3c907f3f164498f797994fcd451aae1 186 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_1419.1 c3c907f3f164498f797994fcd451aae1 186 Pfam PF12838 4Fe-4S dicluster domain 65 124 3.3E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_1419.1 c3c907f3f164498f797994fcd451aae1 186 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_1419.1 c3c907f3f164498f797994fcd451aae1 186 Gene3D G3DSA:3.30.70.3270 44 181 4.0E-25 T 23-10-2018 APE_1245.1 79387b1bd2a012f6368ff51fa864ed68 326 Gene3D G3DSA:3.90.180.10 13 312 5.4E-70 T 23-10-2018 APE_1245.1 79387b1bd2a012f6368ff51fa864ed68 326 SUPERFAMILY SSF51735 132 294 7.79E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1245.1 79387b1bd2a012f6368ff51fa864ed68 326 SUPERFAMILY SSF50129 2 164 8.37E-43 T 23-10-2018 IPR011032 GroES-like superfamily APE_1245.1 79387b1bd2a012f6368ff51fa864ed68 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 122 5.7E-26 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APE_1245.1 79387b1bd2a012f6368ff51fa864ed68 326 Gene3D G3DSA:3.40.50.720 147 279 5.4E-70 T 23-10-2018 APE_1245.1 79387b1bd2a012f6368ff51fa864ed68 326 Pfam PF00107 Zinc-binding dehydrogenase 168 290 4.6E-12 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APE_0045 f88934af05f8e2e6c893afd610c845c7 373 PIRSF PIRSF002756 1 372 5.1E-127 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 APE_0045 f88934af05f8e2e6c893afd610c845c7 373 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 46 369 5.1E-93 T 23-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 APE_0045 f88934af05f8e2e6c893afd610c845c7 373 Gene3D G3DSA:3.40.190.10 50 357 1.8E-103 T 23-10-2018 APE_0045 f88934af05f8e2e6c893afd610c845c7 373 Pfam PF12849 PBP superfamily domain 39 339 6.5E-53 T 23-10-2018 IPR024370 PBP domain APE_0045 f88934af05f8e2e6c893afd610c845c7 373 Gene3D G3DSA:3.40.190.10 123 312 1.8E-103 T 23-10-2018 APE_0045 f88934af05f8e2e6c893afd610c845c7 373 SUPERFAMILY SSF53850 46 371 5.18E-89 T 23-10-2018 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 PRINTS PR01868 ABC transporter family E signature 160 186 4.3E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 PRINTS PR01868 ABC transporter family E signature 55 79 4.3E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 PRINTS PR01868 ABC transporter family E signature 144 160 4.3E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 PRINTS PR01868 ABC transporter family E signature 25 40 4.3E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 PRINTS PR01868 ABC transporter family E signature 110 135 4.3E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 PRINTS PR01868 ABC transporter family E signature 82 102 4.3E-61 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 SUPERFAMILY SSF52540 104 295 6.86E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 Pfam PF00005 ABC transporter 380 507 3.4E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 SMART SM00382 105 296 1.6E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 SMART SM00382 382 555 6.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 Pfam PF00037 4Fe-4S binding domain 51 74 1.1E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 ProSitePatterns PS00211 ABC transporters family signature. 221 235 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 8 38 2.7E-13 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 Gene3D G3DSA:3.40.50.300 4 336 1.8E-79 T 23-10-2018 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 SUPERFAMILY SSF54862 6 99 5.67E-18 T 23-10-2018 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 Gene3D G3DSA:3.40.50.300 351 614 4.1E-48 T 23-10-2018 APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 SUPERFAMILY SSF52540 363 554 2.92E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1119.1 d6f2022d034371ce7e2f694b7920109d 614 Pfam PF00005 ABC transporter 105 248 2.3E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0367.1 27cca8f516f875036765371d43fa045c 144 PRINTS PR00975 Ribosomal protein S19 family signature 109 124 2.5E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 PRINTS PR00975 Ribosomal protein S19 family signature 77 96 2.5E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 PRINTS PR00975 Ribosomal protein S19 family signature 97 109 2.5E-18 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 ProSitePatterns PS00323 Ribosomal protein S19 signature. 97 121 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 SUPERFAMILY SSF54570 60 128 6.8E-27 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 38 133 24.17 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 Pfam PF00203 Ribosomal protein S19 40 127 7.2E-33 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 PIRSF PIRSF002144 3 144 2.0E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 10 143 6.5E-61 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0367.1 27cca8f516f875036765371d43fa045c 144 Gene3D G3DSA:3.30.860.20 4 143 3.5E-50 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 PIRSF PIRSF500824 1 427 1.8E-184 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 PIRSF PIRSF001413 1 425 3.3E-154 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 SUPERFAMILY SSF53686 38 417 6.29E-98 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 Gene3D G3DSA:3.40.50.1100 5 234 1.3E-147 T 23-10-2018 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 419 40.002 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 4 422 6.6E-202 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 Gene3D G3DSA:3.40.50.1100 4 412 1.3E-147 T 23-10-2018 APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 69 406 2.5E-47 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_2548 93add4c578c4e9e4a8072c04e8b7bfb7 427 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 100 114 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2371.1 9004c125c62634e22e60c6ad9dbc0ec7 235 Pfam PF01092 Ribosomal protein S6e 126 232 1.4E-22 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2371.1 9004c125c62634e22e60c6ad9dbc0ec7 235 SMART SM01405 120 235 8.0E-38 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2371.1 9004c125c62634e22e60c6ad9dbc0ec7 235 ProSitePatterns PS00578 Ribosomal protein S6e signature. 160 171 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2371.1 9004c125c62634e22e60c6ad9dbc0ec7 235 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 6 230 31.662 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 4.2E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 PRINTS PR00599 Methionine aminopeptidase-1 signature 147 159 4.2E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 4.2E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 PRINTS PR00599 Methionine aminopeptidase-1 signature 180 192 4.2E-15 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 Pfam PF00557 Metallopeptidase family M24 9 205 9.3E-35 T 23-10-2018 IPR000994 Peptidase M24 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 SUPERFAMILY SSF46785 199 276 1.5E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 SUPERFAMILY SSF55920 11 300 2.49E-56 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 7 301 7.2E-85 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 Hamap MF_01975 Methionine aminopeptidase [map]. 6 300 45.156 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 Gene3D G3DSA:1.10.10.10 199 277 8.6E-83 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1114.1 685c40b7a9cf3f8009def548361fc8e8 307 Gene3D G3DSA:3.90.230.10 11 290 8.6E-83 T 23-10-2018 APE_2020 624a7163081c2f6a3317a7cb02a2023a 146 SUPERFAMILY SSF88697 79 145 4.29E-11 T 23-10-2018 IPR015947 PUA-like superfamily APE_2020 624a7163081c2f6a3317a7cb02a2023a 146 Gene3D G3DSA:3.10.450.90 13 76 9.9E-9 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 APE_2020 624a7163081c2f6a3317a7cb02a2023a 146 Gene3D G3DSA:2.30.130.10 77 146 6.3E-14 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 APE_2020 624a7163081c2f6a3317a7cb02a2023a 146 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 14 78 1.8E-11 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 APE_2020 624a7163081c2f6a3317a7cb02a2023a 146 SUPERFAMILY SSF88802 4 74 1.24E-11 T 23-10-2018 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 SUPERFAMILY SSF47323 700 836 8.78E-28 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 SUPERFAMILY SSF52374 4 684 3.84E-98 T 23-10-2018 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Gene3D G3DSA:3.40.50.620 7 665 4.6E-271 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 4 955 17.209 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 397 664 1.5E-16 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 10 325 4.7E-41 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Gene3D G3DSA:3.30.2320.20 819 955 3.0E-23 T 23-10-2018 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 6 954 2.9E-294 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 SUPERFAMILY SSF50677 206 434 3.53E-37 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Gene3D G3DSA:1.10.730.10 686 794 8.8E-18 T 23-10-2018 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Gene3D G3DSA:3.90.740.10 201 442 4.6E-271 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Pfam PF08264 Anticodon-binding domain of tRNA 713 831 1.9E-21 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APE_1015 3df11b4b0227d1843ed2dea6f3be94e0 959 Gene3D G3DSA:1.10.10.720 848 904 3.0E-23 T 23-10-2018 APE_0790 ab0cd6a6cdbd889643c2015e6d57cbd1 297 SUPERFAMILY SSF58104 161 252 9.15E-5 T 23-10-2018 APE_0790 ab0cd6a6cdbd889643c2015e6d57cbd1 297 Gene3D G3DSA:1.20.5.340 120 254 2.8E-8 T 23-10-2018 APE_0226.1 02e8b3712dd152e9070cbaa1ebe002c5 270 Pfam PF02598 Putative RNA methyltransferase 1 256 1.5E-42 T 23-10-2018 IPR003750 Putative RNA methyltransferase APE_0226.1 02e8b3712dd152e9070cbaa1ebe002c5 270 Gene3D G3DSA:3.40.1280.10 1 257 1.3E-64 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APE_0226.1 02e8b3712dd152e9070cbaa1ebe002c5 270 Gene3D G3DSA:2.40.50.140 90 154 1.3E-64 T 23-10-2018 APE_0226.1 02e8b3712dd152e9070cbaa1ebe002c5 270 SUPERFAMILY SSF75217 1 260 7.5E-38 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_0490.1 2df2f71cc3e9d9effa3276cc0df9b535 229 SUPERFAMILY SSF53271 8 161 7.53E-30 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_0490.1 2df2f71cc3e9d9effa3276cc0df9b535 229 Gene3D G3DSA:3.40.50.2020 4 175 8.6E-34 T 23-10-2018 APE_0490.1 2df2f71cc3e9d9effa3276cc0df9b535 229 Pfam PF00156 Phosphoribosyl transferase domain 22 149 1.4E-14 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APE_1851.1 2348327a68178b351f51d292af20d50e 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 3 94 3.6E-20 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 APE_1851.1 2348327a68178b351f51d292af20d50e 100 PRINTS PR00884 Ribosomal protein HS6 signature 34 45 4.4E-5 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1851.1 2348327a68178b351f51d292af20d50e 100 PRINTS PR00884 Ribosomal protein HS6 signature 24 34 4.4E-5 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1851.1 2348327a68178b351f51d292af20d50e 100 PRINTS PR00884 Ribosomal protein HS6 signature 61 71 4.4E-5 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1851.1 2348327a68178b351f51d292af20d50e 100 PRINTS PR00884 Ribosomal protein HS6 signature 75 91 4.4E-5 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1851.1 2348327a68178b351f51d292af20d50e 100 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 1 98 27.453 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1851.1 2348327a68178b351f51d292af20d50e 100 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 69 89 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1851.1 2348327a68178b351f51d292af20d50e 100 Gene3D G3DSA:3.30.1330.30 1 99 1.7E-33 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1851.1 2348327a68178b351f51d292af20d50e 100 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 13 37 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1851.1 2348327a68178b351f51d292af20d50e 100 SUPERFAMILY SSF55315 2 95 4.38E-26 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_2211.1 7964491bcd5a930c57379ab8e9d5425d 144 Pfam PF02566 OsmC-like protein 45 138 7.5E-12 T 23-10-2018 IPR003718 OsmC/Ohr family APE_2211.1 7964491bcd5a930c57379ab8e9d5425d 144 Gene3D G3DSA:3.30.300.20 21 143 2.8E-14 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta APE_2211.1 7964491bcd5a930c57379ab8e9d5425d 144 SUPERFAMILY SSF82784 15 142 7.98E-19 T 23-10-2018 IPR036102 OsmC/Ohr superfamily APE_2115.1 53beb938470459dd114ff4a58c02ca02 391 Pfam PF01979 Amidohydrolase family 32 298 4.6E-6 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APE_2115.1 53beb938470459dd114ff4a58c02ca02 391 SUPERFAMILY SSF51556 35 297 5.53E-21 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_2115.1 53beb938470459dd114ff4a58c02ca02 391 Gene3D G3DSA:3.20.20.140 39 312 2.9E-17 T 23-10-2018 APE_2071.1 006ed9b03cbe91a732ec7d49203334b8 178 Gene3D G3DSA:3.40.50.2020 17 176 1.3E-49 T 23-10-2018 APE_2071.1 006ed9b03cbe91a732ec7d49203334b8 178 SUPERFAMILY SSF53271 20 171 2.62E-33 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_2071.1 006ed9b03cbe91a732ec7d49203334b8 178 Pfam PF00156 Phosphoribosyl transferase domain 23 163 8.8E-27 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APE_1091 380d8bf34b9329851c36c46b0c472d8f 107 Pfam PF01985 CRS1 / YhbY (CRM) domain 8 86 6.0E-14 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 APE_1091 380d8bf34b9329851c36c46b0c472d8f 107 SUPERFAMILY SSF75471 7 93 6.15E-16 T 23-10-2018 IPR035920 YhbY-like superfamily APE_1091 380d8bf34b9329851c36c46b0c472d8f 107 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 89 8.0E-20 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 APE_1091 380d8bf34b9329851c36c46b0c472d8f 107 Gene3D G3DSA:3.30.110.60 3 101 3.0E-18 T 23-10-2018 IPR035920 YhbY-like superfamily APE_1091 380d8bf34b9329851c36c46b0c472d8f 107 SMART SM01103 4 86 3.1E-17 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 SUPERFAMILY SSF54631 171 296 8.84E-33 T 23-10-2018 APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 PIRSF PIRSF005063 1 299 2.1E-119 T 23-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 Pfam PF00571 CBS domain 178 228 4.6E-10 T 23-10-2018 IPR000644 CBS domain APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 Pfam PF00571 CBS domain 243 295 2.4E-13 T 23-10-2018 IPR000644 CBS domain APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 SUPERFAMILY SSF46785 3 78 3.97E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 SMART SM00116 184 232 9.5E-9 T 23-10-2018 IPR000644 CBS domain APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 SMART SM00116 248 296 2.9E-10 T 23-10-2018 IPR000644 CBS domain APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 Gene3D G3DSA:1.10.10.10 9 74 3.5E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 3 80 3.0E-35 T 23-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 APE_0974.1 7fa35e219aa87954f6518ceff12f01ad 299 Gene3D G3DSA:3.10.580.10 169 296 2.5E-33 T 23-10-2018 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 Pfam PF01145 SPFH domain / Band 7 family 34 204 7.7E-39 T 23-10-2018 IPR001107 Band 7 domain APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 Gene3D G3DSA:3.30.479.30 58 189 3.0E-52 T 23-10-2018 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 SUPERFAMILY SSF117892 61 194 9.02E-45 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 37 59 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 139 162 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 163 181 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 207 230 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 182 203 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 119 136 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 PRINTS PR00721 Stomatin signature 84 105 9.2E-65 T 23-10-2018 IPR001972 Stomatin family GO:0016020 APE_2153.1 2f1b97def9e46db2a5a485b9c19c0338 271 SMART SM00244 30 187 1.0E-68 T 23-10-2018 IPR001107 Band 7 domain APE_1586a 5c34bb9a4e756354d74be69c1e7df3ef 48 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 4 40 1.2E-7 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_1586a 5c34bb9a4e756354d74be69c1e7df3ef 48 Gene3D G3DSA:1.20.140.10 2 46 2.1E-9 T 23-10-2018 APE_1586a 5c34bb9a4e756354d74be69c1e7df3ef 48 SUPERFAMILY SSF47203 4 40 3.54E-10 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_1688.1 37471b97db075fda76eff6f2c2f2d98a 274 Gene3D G3DSA:3.40.50.1980 10 139 7.8E-25 T 23-10-2018 APE_1688.1 37471b97db075fda76eff6f2c2f2d98a 274 Gene3D G3DSA:3.40.50.1980 142 269 6.9E-9 T 23-10-2018 APE_1688.1 37471b97db075fda76eff6f2c2f2d98a 274 SUPERFAMILY SSF53807 10 266 4.32E-41 T 23-10-2018 APE_1688.1 37471b97db075fda76eff6f2c2f2d98a 274 Pfam PF01497 Periplasmic binding protein 25 223 9.9E-21 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 SMART SM00946 416 485 7.9E-24 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Gene3D G3DSA:3.30.930.10 7 285 6.2E-78 T 23-10-2018 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 SUPERFAMILY SSF64586 412 485 5.1E-19 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 PRINTS PR01046 Prolyl-tRNA synthetase signature 108 119 1.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 PRINTS PR01046 Prolyl-tRNA synthetase signature 148 159 1.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 PRINTS PR01046 Prolyl-tRNA synthetase signature 67 85 1.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 PRINTS PR01046 Prolyl-tRNA synthetase signature 138 146 1.2E-10 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 485 40.44 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 SUPERFAMILY SSF55681 12 279 3.38E-75 T 23-10-2018 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Gene3D G3DSA:3.40.50.800 286 406 1.3E-33 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 274 4.9E-23 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 SUPERFAMILY SSF52954 281 408 7.25E-32 T 23-10-2018 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 417 485 8.8E-13 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Pfam PF03129 Anticodon binding domain 292 389 3.5E-21 T 23-10-2018 IPR004154 Anticodon-binding APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 Gene3D G3DSA:3.30.110.30 412 484 1.4E-14 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2328 b0a9f30b1593c7817c6a6395ff00b629 485 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 11 485 5.1E-170 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 SUPERFAMILY SSF55008 76 144 9.56E-13 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 SUPERFAMILY SSF56784 485 789 5.0E-56 T 23-10-2018 IPR036412 HAD-like superfamily APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 226 795 7.4E-178 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Gene3D G3DSA:3.30.70.100 7 73 6.5E-18 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Gene3D G3DSA:2.70.150.20 281 393 1.3E-36 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Gene3D G3DSA:3.30.70.100 74 148 3.2E-10 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 710 722 2.7E-30 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 687 706 2.7E-30 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 2.7E-30 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 2.7E-30 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 644 2.7E-30 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 623 2.7E-30 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 SUPERFAMILY SSF81653 291 388 4.32E-29 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Pfam PF00702 haloacid dehalogenase-like hydrolase 485 701 8.1E-45 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Gene3D G3DSA:3.40.50.1000 468 739 2.9E-92 T 23-10-2018 IPR023214 HAD superfamily APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 SUPERFAMILY SSF55008 8 75 5.37E-18 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Pfam PF00403 Heavy-metal-associated domain 11 71 3.9E-12 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Pfam PF00403 Heavy-metal-associated domain 79 139 3.2E-9 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Pfam PF00122 E1-E2 ATPase 288 466 4.4E-54 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 SUPERFAMILY SSF81665 242 771 1.7E-13 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 208 795 1.1E-166 T 23-10-2018 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 554 572 2.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 659 675 2.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 687 703 2.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 718 743 2.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 Gene3D G3DSA:3.40.1110.10 498 619 2.9E-92 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 APE_1454.1 f06a90024e98e1b43483116c0dbbb8bb 838 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 261 768 5.3E-97 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 PIRSF PIRSF002116 2 252 1.2E-96 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Pfam PF00900 Ribosomal family S4e 96 178 9.8E-24 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Gene3D G3DSA:2.40.50.740 123 183 3.8E-23 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 SMART SM00363 43 107 7.7E-8 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 186 2.0E-51 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Gene3D G3DSA:2.30.30.30 184 251 5.7E-21 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Pfam PF01479 S4 domain 51 91 2.3E-14 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 247 42.527 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Gene3D G3DSA:3.10.290.40 1 118 2.4E-41 T 23-10-2018 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 SUPERFAMILY SSF55174 53 108 3.4E-8 T 23-10-2018 APE_0356.1 93f6fe807a25e5c2a5ce12c9d9332a65 253 Pfam PF08071 RS4NT (NUC023) domain 4 39 4.0E-15 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1934.1 dcecdc1639cede2eaf715d8a6e2bbbb0 255 SUPERFAMILY SSF52540 19 236 6.82E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1934.1 dcecdc1639cede2eaf715d8a6e2bbbb0 255 Gene3D G3DSA:3.40.50.300 16 253 1.0E-56 T 23-10-2018 APE_1934.1 dcecdc1639cede2eaf715d8a6e2bbbb0 255 SMART SM00382 39 223 5.3E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1934.1 dcecdc1639cede2eaf715d8a6e2bbbb0 255 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1934.1 dcecdc1639cede2eaf715d8a6e2bbbb0 255 Pfam PF00005 ABC transporter 30 175 1.6E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0535 423fa2f9bb86f96941e0eaf30c8480a4 128 SUPERFAMILY SSF47598 3 43 1.91E-8 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APE_0535 423fa2f9bb86f96941e0eaf30c8480a4 128 SUPERFAMILY SSF55021 51 127 4.58E-10 T 23-10-2018 APE_0535 423fa2f9bb86f96941e0eaf30c8480a4 128 Pfam PF08753 NikR C terminal nickel binding domain 69 114 5.2E-5 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal APE_0535 423fa2f9bb86f96941e0eaf30c8480a4 128 Pfam PF12651 Ribbon-helix-helix domain 3 45 2.5E-17 T 23-10-2018 IPR038733 Predicted DNA-binding protein, ribbon-helix-helix domain APE_1216 c617ef91b3dbae153695373f8ed93561 533 Gene3D G3DSA:3.90.20.10 389 507 2.3E-5 T 23-10-2018 APE_1216 c617ef91b3dbae153695373f8ed93561 533 Gene3D G3DSA:1.20.5.340 221 325 2.6E-12 T 23-10-2018 APE_1216 c617ef91b3dbae153695373f8ed93561 533 Gene3D G3DSA:1.20.5.340 326 387 5.7E-8 T 23-10-2018 APE_1216 c617ef91b3dbae153695373f8ed93561 533 Pfam PF15619 Ciliary protein causing Leber congenital amaurosis disease 265 442 1.8E-7 T 23-10-2018 IPR028933 Lebercilin domain APE_1216 c617ef91b3dbae153695373f8ed93561 533 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 260 507 2.0E-4 T 23-10-2018 APE_1216 c617ef91b3dbae153695373f8ed93561 533 SUPERFAMILY SSF57997 247 497 1.63E-19 T 23-10-2018 APE_1896.1 6cb9523a93a8200a3396d394b50c82a2 576 Gene3D G3DSA:3.40.50.300 284 519 1.7E-82 T 23-10-2018 APE_1896.1 6cb9523a93a8200a3396d394b50c82a2 576 Gene3D G3DSA:3.30.450.370 59 282 1.8E-61 T 23-10-2018 APE_1896.1 6cb9523a93a8200a3396d394b50c82a2 576 Gene3D G3DSA:1.10.8.1140 520 571 2.4E-23 T 23-10-2018 APE_1896.1 6cb9523a93a8200a3396d394b50c82a2 576 SUPERFAMILY SSF52540 169 552 1.76E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1896.1 6cb9523a93a8200a3396d394b50c82a2 576 Gene3D G3DSA:1.10.390.40 97 185 1.8E-61 T 23-10-2018 APE_1896.1 6cb9523a93a8200a3396d394b50c82a2 576 Pfam PF00437 Type II/IV secretion system protein 188 450 2.7E-47 T 23-10-2018 IPR001482 Type II/IV secretion system protein APE_1205.1 f0090d300e5f200915ac824cc3097936 617 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 617 1.3E-220 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Pfam PF13522 Glutamine amidotransferase domain 66 196 2.5E-19 T 23-10-2018 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 617 37.384 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Gene3D G3DSA:3.40.50.10490 262 616 1.5E-108 T 23-10-2018 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Gene3D G3DSA:3.40.50.10490 454 602 1.5E-108 T 23-10-2018 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 SUPERFAMILY SSF53697 259 617 2.97E-89 T 23-10-2018 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Gene3D G3DSA:3.60.20.10 2 233 4.4E-67 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Pfam PF01380 SIS domain 470 554 2.2E-11 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 Pfam PF01380 SIS domain 298 423 3.1E-27 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 APE_1205.1 f0090d300e5f200915ac824cc3097936 617 SUPERFAMILY SSF56235 2 231 3.86E-65 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_1388.1 100ae0d192823978e403b1d7ef961b08 295 Pfam PF06267 Family of unknown function (DUF1028) 2 199 1.0E-72 T 23-10-2018 IPR010430 Protein of unknown function DUF1028 APE_1388.1 100ae0d192823978e403b1d7ef961b08 295 SUPERFAMILY SSF56235 1 210 8.49E-69 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_1388.1 100ae0d192823978e403b1d7ef961b08 295 Gene3D G3DSA:3.60.20.10 1 216 2.8E-78 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_1388.1 100ae0d192823978e403b1d7ef961b08 295 Pfam PF08823 Putative peptidoglycan binding domain 209 282 8.1E-27 T 23-10-2018 IPR014927 Putative peptidoglycan binding APE_1874.1 45354e4abaa90383b51e04c166d43530 356 Gene3D G3DSA:3.20.20.70 37 281 1.7E-25 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1874.1 45354e4abaa90383b51e04c166d43530 356 SUPERFAMILY SSF102114 36 222 3.53E-29 T 23-10-2018 APE_1874.1 45354e4abaa90383b51e04c166d43530 356 Pfam PF04055 Radical SAM superfamily 48 215 8.3E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1874.1 45354e4abaa90383b51e04c166d43530 356 SMART SM00729 42 259 2.4E-9 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_2535.1 a0c898e2ef71df9c110af4f1a2277b55 190 Pfam PF06197 Protein of unknown function (DUF998) 11 183 5.4E-28 T 23-10-2018 IPR009339 Protein of unknown function DUF998 APE_1637.1 697b698a3699fe272fc69cc8698806e9 312 TIGRFAM TIGR01230 agmatinase: agmatinase 27 298 4.2E-67 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 APE_1637.1 697b698a3699fe272fc69cc8698806e9 312 Gene3D G3DSA:3.40.800.10 16 304 5.2E-80 T 23-10-2018 APE_1637.1 697b698a3699fe272fc69cc8698806e9 312 ProSitePatterns PS01053 Arginase family signature. 228 249 - T 23-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 APE_1637.1 697b698a3699fe272fc69cc8698806e9 312 PIRSF PIRSF036979 4 304 8.8E-98 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 APE_1637.1 697b698a3699fe272fc69cc8698806e9 312 Pfam PF00491 Arginase family 32 297 6.2E-75 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 APE_1637.1 697b698a3699fe272fc69cc8698806e9 312 SUPERFAMILY SSF52768 28 302 1.26E-75 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Pfam PF00384 Molybdopterin oxidoreductase 255 377 6.1E-10 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Pfam PF00384 Molybdopterin oxidoreductase 614 693 2.4E-6 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 SUPERFAMILY SSF53706 9 787 1.57E-98 T 23-10-2018 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Gene3D G3DSA:3.40.50.740 152 726 4.8E-140 T 23-10-2018 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Gene3D G3DSA:3.40.228.10 244 486 4.8E-140 T 23-10-2018 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Gene3D G3DSA:3.30.200.200 12 678 4.8E-140 T 23-10-2018 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Gene3D G3DSA:2.40.40.20 858 994 5.2E-46 T 23-10-2018 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 Pfam PF01568 Molydopterin dinucleotide binding domain 873 978 1.1E-24 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 TIGRFAM TIGR02693 arsenite_ox_L: arsenite oxidase, large subunit 8 582 2.5E-115 T 23-10-2018 IPR014066 Arsenite oxidase, large subunit MetaCyc: PWY-7429 APE_2556.1 2e7007415c4a1e24753beb37dbc80a87 1006 SUPERFAMILY SSF50692 852 985 1.51E-31 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily APE_0698.1 37957ba55cfba4c651eb50ed77cfcc1e 310 Pfam PF01916 Deoxyhypusine synthase 18 302 5.0E-87 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 APE_0698.1 37957ba55cfba4c651eb50ed77cfcc1e 310 SUPERFAMILY SSF52467 2 308 3.07E-91 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APE_0698.1 37957ba55cfba4c651eb50ed77cfcc1e 310 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 15 306 43.348 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 APE_0698.1 37957ba55cfba4c651eb50ed77cfcc1e 310 Gene3D G3DSA:3.40.910.10 1 309 4.1E-82 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PIRSF PIRSF001529 6 155 3.0E-19 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PIRSF PIRSF001529 142 449 4.4E-107 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 TIGRFAM TIGR00414 serS: serine--tRNA ligase 8 441 3.4E-132 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 SUPERFAMILY SSF55681 157 441 8.64E-72 T 23-10-2018 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 Gene3D G3DSA:1.10.287.40 7 107 5.4E-17 T 23-10-2018 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 Gene3D G3DSA:3.30.930.10 108 451 2.1E-113 T 23-10-2018 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 8 110 7.3E-20 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 Hamap MF_00176 Serine--tRNA ligase [serS]. 4 446 37.789 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PRINTS PR00981 Seryl-tRNA synthetase signature 340 353 1.1E-28 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 1.1E-28 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PRINTS PR00981 Seryl-tRNA synthetase signature 300 313 1.1E-28 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PRINTS PR00981 Seryl-tRNA synthetase signature 375 391 1.1E-28 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 PRINTS PR00981 Seryl-tRNA synthetase signature 288 300 1.1E-28 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 247 423 1.4E-34 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1976.1 7b9904d5472057090ca6324948c1475d 460 SUPERFAMILY SSF46589 8 115 6.8E-21 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 8.4E-37 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 SUPERFAMILY SSF55666 154 240 3.01E-19 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 10 238 2.1E-119 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 57.846 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 SUPERFAMILY SSF54211 10 186 1.52E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 Pfam PF03725 3' exoribonuclease family, domain 2 157 221 5.8E-10 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1447 1308571d0885ef4cfbc89e4e3ecccbf3 246 Gene3D G3DSA:3.30.230.70 9 241 4.8E-72 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 PIRSF PIRSF000130 151 433 2.6E-90 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 PIRSF PIRSF000130 4 156 1.6E-34 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 428 1.6E-105 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 Gene3D G3DSA:3.20.20.70 3 132 3.3E-32 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 SUPERFAMILY SSF51412 11 431 3.66E-91 T 23-10-2018 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 SMART SM01240 12 428 5.0E-139 T 23-10-2018 APE_1507.1 83b9bda8b1d59847580b9fc155d692a6 433 Gene3D G3DSA:3.20.20.70 151 433 6.6E-82 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 PIRSF PIRSF000429 9 402 9.4E-115 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 23-10-2018 IPR020613 Thiolase, conserved site GO:0016747 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 SUPERFAMILY SSF53901 280 401 1.07E-38 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 Gene3D G3DSA:3.40.47.10 153 399 2.9E-128 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 23-10-2018 IPR020610 Thiolase, active site GO:0016747 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 Pfam PF02803 Thiolase, C-terminal domain 279 401 7.4E-41 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 Gene3D G3DSA:3.40.47.10 14 285 2.9E-128 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 15 400 1.2E-138 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 SUPERFAMILY SSF53901 13 279 3.36E-70 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2108 1c8c782b0f74b1b82a21a703920efc45 402 Pfam PF00108 Thiolase, N-terminal domain 13 271 1.6E-65 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 APE_0134.1 bc4aa0b0277ce219205c2b5ab1f6ace4 266 Pfam PF01012 Electron transfer flavoprotein domain 30 216 3.4E-40 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_0134.1 bc4aa0b0277ce219205c2b5ab1f6ace4 266 PIRSF PIRSF000090 2 265 1.8E-67 T 23-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 APE_0134.1 bc4aa0b0277ce219205c2b5ab1f6ace4 266 SMART SM00893 22 220 2.8E-39 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_0134.1 bc4aa0b0277ce219205c2b5ab1f6ace4 266 SUPERFAMILY SSF52402 4 254 2.23E-55 T 23-10-2018 APE_0134.1 bc4aa0b0277ce219205c2b5ab1f6ace4 266 Gene3D G3DSA:3.40.50.620 3 259 5.8E-62 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 335 444 7.0E-33 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 455 3.0E-159 T 23-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 314 2.2E-63 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 331 352 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 139 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 439 3.3E-72 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PIRSF PIRSF000350 2 454 5.4E-78 T 23-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 Gene3D G3DSA:3.50.50.60 4 320 1.1E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 Gene3D G3DSA:3.30.390.30 334 458 8.8E-39 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 1.1E-33 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.1E-33 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-33 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 1.1E-33 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.1E-33 T 23-10-2018 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 SUPERFAMILY SSF51905 3 325 1.75E-56 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 SUPERFAMILY SSF55424 331 455 5.15E-37 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 APE_1669.1 ed11a1d922b3eb378ac9a178f5f333aa 464 Gene3D G3DSA:3.50.50.60 139 257 1.1E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 SUPERFAMILY SSF51735 1 164 2.04E-11 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 188 210 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 Gene3D G3DSA:3.40.50.720 3 316 5.6E-50 T 23-10-2018 APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 Pfam PF00742 Homoserine dehydrogenase 143 316 1.6E-30 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 SUPERFAMILY SSF55347 143 303 3.79E-31 T 23-10-2018 APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 Gene3D G3DSA:3.30.360.10 154 299 5.6E-50 T 23-10-2018 APE_1144.1 18b7361bf8b8e9e9a2e2a92df02a6340 332 PIRSF PIRSF036497 1 325 1.2E-79 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 APE_2139a 9170491a6dfaa09bfe22d505aa1394bf 71 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 25 44 2.2E-5 T 23-10-2018 APE_2139a 9170491a6dfaa09bfe22d505aa1394bf 71 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 5 25 2.2E-5 T 23-10-2018 APE_2139a 9170491a6dfaa09bfe22d505aa1394bf 71 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 5 69 16.213 T 23-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 APE_2139a 9170491a6dfaa09bfe22d505aa1394bf 71 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 7 50 1.5E-15 T 23-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 APE_2139a 9170491a6dfaa09bfe22d505aa1394bf 71 Pfam PF02416 mttA/Hcf106 family 8 55 2.1E-15 T 23-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 176 3.8E-17 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 SUPERFAMILY SSF53790 9 284 1.44E-39 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 Gene3D G3DSA:3.40.1010.10 1 120 1.7E-30 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 Hamap MF_01084 Diphthine synthase [dphB]. 9 267 27.346 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 Gene3D G3DSA:3.30.950.10 121 294 1.7E-79 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 TIGRFAM TIGR00522 dph5: diphthine synthase 10 258 2.1E-35 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 PIRSF PIRSF036432 9 271 2.5E-76 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 APE_0931 0c4e29c8dfbfb01f0a0c446e02ad4391 294 PIRSF PIRSF036432 272 290 160.0 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 Pfam PF08443 RimK-like ATP-grasp domain 91 279 6.0E-27 T 23-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 Gene3D G3DSA:3.30.470.80 176 286 1.4E-32 T 23-10-2018 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 Gene3D G3DSA:3.30.1490.20 108 175 1.1E-18 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 7 280 3.0E-95 T 23-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 SUPERFAMILY SSF56059 92 283 3.69E-39 T 23-10-2018 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 Gene3D G3DSA:3.40.50.20 2 107 2.3E-22 T 23-10-2018 APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 SUPERFAMILY SSF52440 7 92 3.16E-17 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily APE_1463 bb38e7c9adbfa6a868bda300323fee2f 286 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 7 286 4.4E-115 T 23-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 APE_1035.1 4c0cf64f9517e4ea8f4833253c2a4a63 379 Pfam PF07728 AAA domain (dynein-related subfamily) 40 167 2.5E-27 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 APE_1035.1 4c0cf64f9517e4ea8f4833253c2a4a63 379 Gene3D G3DSA:3.40.50.300 5 216 1.1E-48 T 23-10-2018 APE_1035.1 4c0cf64f9517e4ea8f4833253c2a4a63 379 SUPERFAMILY SSF52540 9 199 9.91E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1035.1 4c0cf64f9517e4ea8f4833253c2a4a63 379 SMART SM00382 37 177 0.0024 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0766 5a7323ff17a1d56325d97939a53f8994 239 Gene3D G3DSA:3.40.50.1000 11 217 3.6E-54 T 23-10-2018 IPR023214 HAD superfamily APE_0766 5a7323ff17a1d56325d97939a53f8994 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 146 219 1.7E-12 T 23-10-2018 APE_0766 5a7323ff17a1d56325d97939a53f8994 239 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 11 226 7.8E-37 T 23-10-2018 APE_0766 5a7323ff17a1d56325d97939a53f8994 239 ProSitePatterns PS01229 Hypothetical cof family signature 2. 181 203 - T 23-10-2018 APE_0766 5a7323ff17a1d56325d97939a53f8994 239 Gene3D G3DSA:3.90.1070.10 88 153 3.6E-54 T 23-10-2018 APE_0766 5a7323ff17a1d56325d97939a53f8994 239 Hamap MF_01419 Phosphoglycolate phosphatase. 8 232 29.15 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 APE_0766 5a7323ff17a1d56325d97939a53f8994 239 SUPERFAMILY SSF56784 8 231 5.46E-34 T 23-10-2018 IPR036412 HAD-like superfamily APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.3E-50 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 SUPERFAMILY SSF52922 188 324 4.58E-43 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 SUPERFAMILY SSF52518 3 193 2.21E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 Gene3D G3DSA:3.40.50.920 193 325 6.6E-50 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 SMART SM00861 4 179 2.9E-73 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 Gene3D G3DSA:3.40.50.970 1 192 7.4E-89 T 23-10-2018 APE_1674 7ca75eeb5f0827aeca7e4d9b75d23ec3 325 Pfam PF02780 Transketolase, C-terminal domain 194 315 4.5E-39 T 23-10-2018 IPR033248 Transketolase, C-terminal domain APE_1691 cab88416230bae0870b04dfca7dcff10 269 Pfam PF02535 ZIP Zinc transporter 127 264 1.2E-13 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 APE_2570.1 b01977cb763a01ba596c1bdf5fddc3bb 128 Gene3D G3DSA:3.30.70.1150 28 126 4.1E-6 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal APE_2570.1 b01977cb763a01ba596c1bdf5fddc3bb 128 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 1.2E-6 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 APE_2570.1 b01977cb763a01ba596c1bdf5fddc3bb 128 SUPERFAMILY SSF47598 3 45 7.23E-10 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APE_2570.1 b01977cb763a01ba596c1bdf5fddc3bb 128 Pfam PF08753 NikR C terminal nickel binding domain 55 124 1.4E-5 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal APE_2570.1 b01977cb763a01ba596c1bdf5fddc3bb 128 SUPERFAMILY SSF55021 55 124 5.95E-8 T 23-10-2018 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 Pfam PF00224 Pyruvate kinase, barrel domain 5 333 2.6E-87 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 Gene3D G3DSA:3.40.1380.20 333 454 8.3E-22 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 SUPERFAMILY SSF50800 71 156 5.76E-16 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 SUPERFAMILY SSF52935 338 440 1.15E-11 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 Gene3D G3DSA:2.40.33.10 71 160 1.5E-27 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 236 260 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 209 235 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 286 304 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 178 192 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 261 285 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 PRINTS PR01050 Pyruvate kinase family signature 305 321 1.4E-46 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 455 2.0E-148 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 APE_0489 bb22e4201236b1e9629b280fd628e8e5 458 SUPERFAMILY SSF51621 3 328 1.14E-73 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 Pfam PF01676 Metalloenzyme superfamily 2 408 3.6E-27 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 PIRSF PIRSF006392 1 423 1.5E-127 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 36 223 7.8E-51 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 1 421 40.679 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 SUPERFAMILY SSF53649 2 392 7.06E-25 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 Gene3D G3DSA:3.30.70.2130 75 245 6.8E-98 T 23-10-2018 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 Gene3D G3DSA:3.40.720.10 4 410 6.8E-98 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APE_1616.1 4158380210a015b11526ec0b0bf9887a 424 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 6 410 1.9E-99 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 SUPERFAMILY SSF52402 23 208 1.05E-40 T 23-10-2018 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 Gene3D G3DSA:3.40.50.1220 220 355 4.9E-52 T 23-10-2018 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 224 306 6.5E-33 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 SMART SM00893 24 216 3.6E-39 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 SUPERFAMILY SSF52467 223 343 7.44E-43 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 Pfam PF01012 Electron transfer flavoprotein domain 24 204 2.3E-38 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 PIRSF PIRSF000089 20 348 1.1E-114 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 APE_2419 752a7fbe4d85d3d8a02eedd713c33ed3 372 Gene3D G3DSA:3.40.50.620 20 219 2.1E-53 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2546 336e7ecd936f8a72225eb7be1637ea7b 261 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 23-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 APE_2546 336e7ecd936f8a72225eb7be1637ea7b 261 Pfam PF00218 Indole-3-glycerol phosphate synthase 8 253 9.1E-52 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 APE_2546 336e7ecd936f8a72225eb7be1637ea7b 261 Gene3D G3DSA:3.20.20.70 4 259 2.7E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2546 336e7ecd936f8a72225eb7be1637ea7b 261 SUPERFAMILY SSF51366 49 252 3.53E-50 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_2546 336e7ecd936f8a72225eb7be1637ea7b 261 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 33 254 30.164 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 APE_0085.1 eaddd4c03c5d503534ca3c066c020909 219 Gene3D G3DSA:3.20.20.140 1 197 1.5E-37 T 23-10-2018 APE_0085.1 eaddd4c03c5d503534ca3c066c020909 219 SMART SM00481 3 69 8.8E-20 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal APE_0085.1 eaddd4c03c5d503534ca3c066c020909 219 SUPERFAMILY SSF89550 1 199 4.84E-41 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 APE_0085.1 eaddd4c03c5d503534ca3c066c020909 219 Pfam PF02811 PHP domain 4 78 1.6E-7 T 23-10-2018 IPR004013 PHP domain GO:0003824 APE_0085.1 eaddd4c03c5d503534ca3c066c020909 219 Pfam PF13263 PHP-associated 140 193 1.3E-13 T 23-10-2018 APE_2139.1 82505996b0e3eacfe60b3684156e6a71 223 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 3 222 1.3E-42 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 APE_2139.1 82505996b0e3eacfe60b3684156e6a71 223 Pfam PF01987 Mitochondrial biogenesis AIM24 10 206 2.6E-45 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 APE_2139.1 82505996b0e3eacfe60b3684156e6a71 223 SUPERFAMILY SSF51219 3 222 6.02E-56 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily APE_2139.1 82505996b0e3eacfe60b3684156e6a71 223 Gene3D G3DSA:3.60.160.10 1 223 1.1E-60 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily APE_1308 2c7bc70a64b605e0343006fa88662b45 250 Gene3D G3DSA:3.40.50.300 1 250 1.6E-64 T 23-10-2018 APE_1308 2c7bc70a64b605e0343006fa88662b45 250 Pfam PF00005 ABC transporter 17 178 6.9E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1308 2c7bc70a64b605e0343006fa88662b45 250 SMART SM00382 26 235 9.8E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1308 2c7bc70a64b605e0343006fa88662b45 250 SUPERFAMILY SSF52540 2 248 6.85E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1308 2c7bc70a64b605e0343006fa88662b45 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 249 6.8E-8 T 23-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal APE_0345.1 c1b2ea85de178552db137613a137aaaf 159 Pfam PF00327 Ribosomal protein L30p/L7e 4 52 2.2E-11 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain APE_0345.1 c1b2ea85de178552db137613a137aaaf 159 Gene3D G3DSA:1.10.15.30 61 118 1.5E-44 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type APE_0345.1 c1b2ea85de178552db137613a137aaaf 159 SUPERFAMILY SSF55129 3 158 3.79E-41 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily APE_0345.1 c1b2ea85de178552db137613a137aaaf 159 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 159 1.0E-64 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 APE_0345.1 c1b2ea85de178552db137613a137aaaf 159 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 159 72.738 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 APE_0345.1 c1b2ea85de178552db137613a137aaaf 159 Gene3D G3DSA:3.30.1390.20 5 147 1.5E-44 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 246 261 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 Pfam PF00120 Glutamine synthetase, catalytic domain 98 455 1.5E-118 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 10 456 6.9E-184 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 SUPERFAMILY SSF55931 97 457 2.26E-106 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 SUPERFAMILY SSF54368 18 94 7.85E-15 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 ProSitePatterns PS00180 Glutamine synthetase signature 1. 47 65 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 18 90 4.4E-14 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 Gene3D G3DSA:3.30.590.10 100 446 1.0E-113 T 23-10-2018 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 SMART SM01230 97 368 1.6E-108 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APE_2142.1 1fb148ca1a7381ac2b4bbd10ed156c4b 458 Gene3D G3DSA:3.10.20.70 16 99 3.6E-15 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 APE_1559a 47febc4920918669d1d29ed00df31704 59 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 42 3.2E-13 T 23-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 APE_1559a 47febc4920918669d1d29ed00df31704 59 Gene3D G3DSA:3.40.5.90 2 57 3.4E-20 T 23-10-2018 APE_1559a 47febc4920918669d1d29ed00df31704 59 SMART SM00704 11 48 4.2E-17 T 23-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 SUPERFAMILY SSF54631 142 274 9.54E-23 T 23-10-2018 APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Gene3D G3DSA:3.10.580.10 1 73 1.5E-6 T 23-10-2018 APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Pfam PF00571 CBS domain 83 136 0.0075 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Pfam PF00571 CBS domain 146 199 2.2E-6 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Pfam PF00571 CBS domain 227 264 6.8E-8 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Pfam PF00571 CBS domain 13 67 1.7E-5 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 SUPERFAMILY SSF54631 6 134 9.1E-16 T 23-10-2018 APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 SMART SM00116 20 67 0.6 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 SMART SM00116 88 136 9.5 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 SMART SM00116 228 275 3.6E-6 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 SMART SM00116 153 200 4.8 T 23-10-2018 IPR000644 CBS domain APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Gene3D G3DSA:3.10.580.10 79 203 6.9E-19 T 23-10-2018 APE_2178.1 686a85e2ea0811f4993dc9866d74f3e0 280 Gene3D G3DSA:3.10.580.10 204 280 4.2E-10 T 23-10-2018 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 157 178 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 SUPERFAMILY SSF56053 87 178 2.78E-29 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 179 38.596 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 PIRSF PIRSF002162 6 180 1.4E-34 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 SUPERFAMILY SSF56053 9 86 5.76E-19 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 Gene3D G3DSA:3.90.930.12 87 181 1.8E-36 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 Gene3D G3DSA:3.90.930.12 8 86 6.1E-24 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 Pfam PF00347 Ribosomal protein L6 13 86 9.3E-18 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 Pfam PF00347 Ribosomal protein L6 98 172 3.3E-14 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0350 eafdc9b869d6f4a498813e548f42a8a6 182 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 9 178 6.1E-71 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 APE_2273.1 4f1181d603d79e8ebd8e38f32bda10af 394 Gene3D G3DSA:3.40.30.10 41 159 1.0E-17 T 23-10-2018 APE_2273.1 4f1181d603d79e8ebd8e38f32bda10af 394 Pfam PF00085 Thioredoxin 62 150 1.9E-13 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 APE_2273.1 4f1181d603d79e8ebd8e38f32bda10af 394 SUPERFAMILY SSF52833 52 157 3.29E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 SUPERFAMILY SSF53613 5 297 5.77E-53 T 23-10-2018 IPR029056 Ribokinase-like APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 Pfam PF00294 pfkB family carbohydrate kinase 6 285 7.5E-34 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 PRINTS PR00990 Ribokinase signature 6 27 3.3E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 PRINTS PR00990 Ribokinase signature 33 52 3.3E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 PRINTS PR00990 Ribokinase signature 105 118 3.3E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_2106.1 e66cb2766524a0900ab5fa34010c4725 306 Gene3D G3DSA:3.40.1190.20 3 296 4.1E-54 T 23-10-2018 IPR029056 Ribokinase-like APE_0880 7614c76fea8a4e486b8e1fe9fd0a591b 534 SUPERFAMILY SSF52540 51 193 3.51E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0880 7614c76fea8a4e486b8e1fe9fd0a591b 534 Gene3D G3DSA:3.40.50.300 35 184 7.0E-6 T 23-10-2018 APE_0880 7614c76fea8a4e486b8e1fe9fd0a591b 534 SMART SM00382 50 191 4.3E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0256a.1 fdec23f770be0cca334e5cdc754eabfc 72 Pfam PF06093 Spt4/RpoE2 zinc finger 9 60 2.9E-11 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 APE_0256a.1 fdec23f770be0cca334e5cdc754eabfc 72 SUPERFAMILY SSF63393 4 66 6.28E-18 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 APE_0256a.1 fdec23f770be0cca334e5cdc754eabfc 72 SMART SM01389 7 67 9.0E-22 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 APE_0256a.1 fdec23f770be0cca334e5cdc754eabfc 72 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 24 66 7.0E-19 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 APE_0256a.1 fdec23f770be0cca334e5cdc754eabfc 72 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 9 67 27.271 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 APE_0256a.1 fdec23f770be0cca334e5cdc754eabfc 72 Gene3D G3DSA:2.20.28.90 2 67 2.3E-22 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily APE_1998 3ed4efd8f73e952c70967128dead78a1 410 Hamap MF_02096 DNA repair protein. 1 408 34.674 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 APE_1998 3ed4efd8f73e952c70967128dead78a1 410 Pfam PF04894 Archaeal Nre, N-terminal 18 291 5.7E-91 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal APE_1998 3ed4efd8f73e952c70967128dead78a1 410 Pfam PF04895 Archaeal Nre, C-terminal 308 408 1.4E-23 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 Pfam PF13183 4Fe-4S dicluster domain 164 235 1.4E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 SUPERFAMILY SSF46548 121 250 2.79E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 67 75 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 21 245 1.2E-75 T 23-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 Gene3D G3DSA:3.10.20.30 7 119 1.5E-35 T 23-10-2018 IPR012675 Beta-grasp domain superfamily APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 Gene3D G3DSA:1.10.1060.10 120 259 3.5E-40 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 SUPERFAMILY SSF54292 16 119 2.36E-29 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 20 125 4.5E-34 T 23-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0946 6157893ab1d1484c5d73c0c3b0af6cdb 305 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 165 176 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 Gene3D G3DSA:1.10.340.30 35 145 1.4E-28 T 23-10-2018 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 SUPERFAMILY SSF48150 39 227 4.71E-55 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 PIRSF PIRSF001435 12 229 2.6E-74 T 23-10-2018 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 188 1.2E-21 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 Gene3D G3DSA:1.10.1670.10 146 229 5.2E-21 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 SMART SM00525 208 228 2.5E-5 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 SMART SM00478 51 207 2.6E-38 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APE_0150.1 c4022cf1efa3b1d01304ee8cbe1c138b 229 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 209 225 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APE_1132.1 6f35728c58fd3ede1e1a463465b8e6ce 118 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 28 95 9.0E-33 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1132.1 6f35728c58fd3ede1e1a463465b8e6ce 118 Pfam PF01282 Ribosomal protein S24e 40 109 4.7E-19 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1132.1 6f35728c58fd3ede1e1a463465b8e6ce 118 SUPERFAMILY SSF54189 22 113 4.32E-26 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1132.1 6f35728c58fd3ede1e1a463465b8e6ce 118 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 20 117 17.362 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1132.1 6f35728c58fd3ede1e1a463465b8e6ce 118 ProSitePatterns PS00529 Ribosomal protein S24e signature. 77 99 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1132.1 6f35728c58fd3ede1e1a463465b8e6ce 118 Gene3D G3DSA:3.30.70.330 21 117 3.8E-25 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily APE_1894 fe49a73cd0ee479a6c6dcbd265aa5213 239 PIRSF PIRSF014439 1 220 4.9E-110 T 23-10-2018 IPR016619 Uncharacterised conserved protein UCP014439, ACT APE_1894 fe49a73cd0ee479a6c6dcbd265aa5213 239 Gene3D G3DSA:3.30.2130.10 75 213 3.4E-7 T 23-10-2018 APE_1894 fe49a73cd0ee479a6c6dcbd265aa5213 239 Pfam PF13840 ACT domain 146 210 1.7E-9 T 23-10-2018 IPR027795 CASTOR, ACT domain APE_1894 fe49a73cd0ee479a6c6dcbd265aa5213 239 SUPERFAMILY SSF55021 147 213 9.41E-8 T 23-10-2018 APE_0389 54005b99408d786d1db1f63f8065ead1 160 Pfam PF00583 Acetyltransferase (GNAT) family 42 148 8.2E-15 T 23-10-2018 IPR000182 GNAT domain APE_0389 54005b99408d786d1db1f63f8065ead1 160 SUPERFAMILY SSF55729 8 152 1.11E-24 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_0389 54005b99408d786d1db1f63f8065ead1 160 Gene3D G3DSA:3.40.630.30 4 154 1.4E-24 T 23-10-2018 APE_0248.1 8ee991203fbba4485ff662bc0ec73568 284 SUPERFAMILY SSF53850 7 272 1.11E-79 T 23-10-2018 APE_0248.1 8ee991203fbba4485ff662bc0ec73568 284 Gene3D G3DSA:3.40.190.10 87 181 1.7E-86 T 23-10-2018 APE_0248.1 8ee991203fbba4485ff662bc0ec73568 284 Pfam PF02621 Menaquinone biosynthesis 7 268 7.2E-86 T 23-10-2018 IPR003773 Menaquinone biosynthesis enzyme APE_0248.1 8ee991203fbba4485ff662bc0ec73568 284 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 6 273 39.1 T 23-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 APE_0248.1 8ee991203fbba4485ff662bc0ec73568 284 Gene3D G3DSA:3.40.190.10 9 268 1.7E-86 T 23-10-2018 APE_1014.1 a7cc251119e0a825fcc31438189ab842 291 Pfam PF01026 TatD related DNase 9 287 4.9E-27 T 23-10-2018 IPR001130 TatD family GO:0016788 APE_1014.1 a7cc251119e0a825fcc31438189ab842 291 SUPERFAMILY SSF51556 7 287 2.38E-24 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_1014.1 a7cc251119e0a825fcc31438189ab842 291 Gene3D G3DSA:3.20.20.140 7 289 2.0E-19 T 23-10-2018 APE_1014.1 a7cc251119e0a825fcc31438189ab842 291 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 159 286 8.0E-62 T 23-10-2018 APE_1014.1 a7cc251119e0a825fcc31438189ab842 291 PIRSF PIRSF004961 2 291 3.7E-100 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 Gene3D G3DSA:3.30.499.20 8 376 4.8E-159 T 23-10-2018 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 Gene3D G3DSA:3.20.19.10 657 897 2.3E-98 T 23-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 ProSitePatterns PS00450 Aconitase family signature 1. 431 447 - T 23-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 376 390 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 435 446 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 296 309 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 282 295 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 173 181 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 206 219 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 497 510 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 149 162 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 PRINTS PR00415 Aconitase family signature 220 235 2.5E-41 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 38 896 0.0 T 23-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 Gene3D G3DSA:3.30.499.10 377 594 1.7E-88 T 23-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 Gene3D G3DSA:1.10.1440.20 595 656 2.3E-21 T 23-10-2018 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 SUPERFAMILY SSF52016 635 896 1.49E-83 T 23-10-2018 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 Pfam PF00694 Aconitase C-terminal domain 696 822 1.0E-39 T 23-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 Pfam PF00330 Aconitase family (aconitate hydratase) 73 566 1.9E-176 T 23-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 APE_1618.1 8756734a459c40c536005d639dd6df8e 903 SUPERFAMILY SSF53732 24 631 4.97E-220 T 23-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Gene3D G3DSA:1.10.8.60 356 450 5.4E-33 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Gene3D G3DSA:3.40.50.300 178 355 2.1E-74 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SUPERFAMILY SSF54585 101 190 1.67E-19 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SMART SM01073 16 100 4.5E-41 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 118 178 1.2E-13 T 23-10-2018 IPR004201 CDC48, domain 2 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 ProSitePatterns PS00674 AAA-protein family signature. 325 343 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Gene3D G3DSA:1.10.8.60 630 702 1.4E-108 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 17 722 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SUPERFAMILY SSF52540 183 447 1.96E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2474.1 7b631d82344b87d111293789f66ea82d 737 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 567 586 2.3E-5 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 229 248 2.3E-5 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SMART SM00382 221 357 1.1E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SMART SM00382 494 631 6.8E-22 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Gene3D G3DSA:3.10.330.10 100 177 4.5E-7 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SUPERFAMILY SSF52540 456 720 2.19E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SUPERFAMILY SSF50692 14 98 7.37E-29 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 17 99 5.2E-33 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain APE_2474.1 7b631d82344b87d111293789f66ea82d 737 ProSitePatterns PS00674 AAA-protein family signature. 599 617 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Gene3D G3DSA:3.40.50.300 456 717 1.4E-108 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 225 355 5.7E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 498 628 3.0E-46 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Gene3D G3DSA:2.40.40.20 11 99 8.3E-35 T 23-10-2018 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 SMART SM01072 116 179 1.3E-13 T 23-10-2018 IPR004201 CDC48, domain 2 APE_2474.1 7b631d82344b87d111293789f66ea82d 737 Pfam PF09336 Vps4 C terminal oligomerisation domain 683 719 9.0E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 Pfam PF13673 Acetyltransferase (GNAT) domain 488 545 1.9E-8 T 23-10-2018 IPR000182 GNAT domain APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 Gene3D G3DSA:3.40.50.12320 209 372 6.7E-21 T 23-10-2018 APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 Pfam PF05127 Helicase 212 381 1.8E-37 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 Pfam PF13718 GNAT acetyltransferase 2 414 466 3.8E-8 T 23-10-2018 IPR000182 GNAT domain APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 SUPERFAMILY SSF52540 191 326 5.54E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 SUPERFAMILY SSF55729 292 551 2.09E-20 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 18 706 42.033 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 APE_1543 3cbb7774077487e9cfb754ae8dddf362 716 Gene3D G3DSA:3.40.630.30 380 563 2.6E-30 T 23-10-2018 APE_0261.1 939b9405881b3cfbe4bd930ba10f4562 425 ProSitePatterns PS00483 Dihydroorotase signature 2. 291 302 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APE_0261.1 939b9405881b3cfbe4bd930ba10f4562 425 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 407 2.9E-133 T 23-10-2018 APE_0261.1 939b9405881b3cfbe4bd930ba10f4562 425 Pfam PF01979 Amidohydrolase family 53 179 7.7E-7 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APE_0261.1 939b9405881b3cfbe4bd930ba10f4562 425 Gene3D G3DSA:3.20.20.140 46 422 1.2E-76 T 23-10-2018 APE_0261.1 939b9405881b3cfbe4bd930ba10f4562 425 Hamap MF_00220_A Dihydroorotase [pyrC]. 10 412 57.258 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 APE_0261.1 939b9405881b3cfbe4bd930ba10f4562 425 SUPERFAMILY SSF51556 56 352 7.33E-62 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 9 489 34.594 T 23-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 PRINTS PR00481 Cytosol aminopeptidase signature 353 368 1.4E-41 T 23-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 PRINTS PR00481 Cytosol aminopeptidase signature 302 323 1.4E-41 T 23-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 PRINTS PR00481 Cytosol aminopeptidase signature 243 260 1.4E-41 T 23-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 PRINTS PR00481 Cytosol aminopeptidase signature 265 286 1.4E-41 T 23-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 PRINTS PR00481 Cytosol aminopeptidase signature 324 344 1.4E-41 T 23-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 SUPERFAMILY SSF52949 24 155 7.06E-13 T 23-10-2018 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 168 481 1.5E-100 T 23-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 Gene3D G3DSA:3.40.630.10 152 490 1.6E-108 T 23-10-2018 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 SUPERFAMILY SSF53187 161 487 1.79E-97 T 23-10-2018 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 328 335 - T 23-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 Gene3D G3DSA:3.40.220.10 20 151 4.8E-10 T 23-10-2018 APE_2450.1 698ae9948ea3fa003f9935bef4fae95b 492 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 25 138 2.1E-7 T 23-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 APE_1659 58536491104bd28214967f0d1dee2d47 335 Pfam PF00248 Aldo/keto reductase family 17 297 6.7E-53 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain APE_1659 58536491104bd28214967f0d1dee2d47 335 Gene3D G3DSA:3.20.20.100 4 309 7.3E-65 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APE_1659 58536491104bd28214967f0d1dee2d47 335 SUPERFAMILY SSF51430 6 301 1.7E-66 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APE_2374 8af57db601dcb68679ce3189a32d6503 617 Gene3D G3DSA:3.40.50.300 9 238 3.3E-65 T 23-10-2018 APE_2374 8af57db601dcb68679ce3189a32d6503 617 Pfam PF14578 Elongation factor Tu domain 4 475 561 4.7E-36 T 23-10-2018 IPR029459 Elongation factor Tu-type domain APE_2374 8af57db601dcb68679ce3189a32d6503 617 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 145 8.0E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 12 605 44.596 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 APE_2374 8af57db601dcb68679ce3189a32d6503 617 SUPERFAMILY SSF52156 344 465 2.62E-31 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily APE_2374 8af57db601dcb68679ce3189a32d6503 617 SUPERFAMILY SSF52540 15 297 4.96E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2374 8af57db601dcb68679ce3189a32d6503 617 Gene3D G3DSA:2.40.30.10 475 564 3.9E-29 T 23-10-2018 APE_2374 8af57db601dcb68679ce3189a32d6503 617 Gene3D G3DSA:2.40.30.10 241 358 4.5E-38 T 23-10-2018 APE_2374 8af57db601dcb68679ce3189a32d6503 617 SUPERFAMILY SSF50447 474 596 4.08E-25 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_2374 8af57db601dcb68679ce3189a32d6503 617 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 13 600 4.2E-246 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 APE_2374 8af57db601dcb68679ce3189a32d6503 617 Gene3D G3DSA:3.40.50.10050 359 466 4.5E-32 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily APE_2374 8af57db601dcb68679ce3189a32d6503 617 Pfam PF00009 Elongation factor Tu GTP binding domain 18 225 1.3E-30 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 PRINTS PR00315 GTP-binding elongation factor signature 100 111 9.9E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 PRINTS PR00315 GTP-binding elongation factor signature 84 94 9.9E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 PRINTS PR00315 GTP-binding elongation factor signature 18 31 9.9E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 PRINTS PR00315 GTP-binding elongation factor signature 136 145 9.9E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 Pfam PF03144 Elongation factor Tu domain 2 256 335 8.3E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APE_2374 8af57db601dcb68679ce3189a32d6503 617 Pfam PF11987 Translation-initiation factor 2 353 455 4.0E-21 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 APE_0193.1 329e906cf2ced19d59cb095c2e7fae17 367 Gene3D G3DSA:3.40.50.720 3 361 4.9E-35 T 23-10-2018 APE_0193.1 329e906cf2ced19d59cb095c2e7fae17 367 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 116 362 1.8E-9 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 APE_0193.1 329e906cf2ced19d59cb095c2e7fae17 367 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 41 3.5E-5 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 APE_0193.1 329e906cf2ced19d59cb095c2e7fae17 367 Gene3D G3DSA:3.30.360.10 117 310 4.9E-35 T 23-10-2018 APE_0193.1 329e906cf2ced19d59cb095c2e7fae17 367 SUPERFAMILY SSF51735 3 121 1.9E-9 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0193.1 329e906cf2ced19d59cb095c2e7fae17 367 SUPERFAMILY SSF55347 118 270 1.31E-11 T 23-10-2018 APE_2071a 436cbf79d5d2883f80d79cc63127b0db 74 SUPERFAMILY SSF116820 1 60 3.27E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2071a 436cbf79d5d2883f80d79cc63127b0db 74 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 20.97 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2071a 436cbf79d5d2883f80d79cc63127b0db 74 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2071a 436cbf79d5d2883f80d79cc63127b0db 74 Gene3D G3DSA:1.10.60.20 1 61 1.0E-27 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2071a 436cbf79d5d2883f80d79cc63127b0db 74 Pfam PF00833 Ribosomal S17 1 61 1.8E-17 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1722a 1472e5ded8c6f81fee146e0b74e36ce0 158 SUPERFAMILY SSF110087 10 149 1.83E-18 T 23-10-2018 IPR036182 Copper chaperone PCuAC superfamily APE_1722a 1472e5ded8c6f81fee146e0b74e36ce0 158 Pfam PF04314 Copper chaperone PCu(A)C 51 133 7.4E-10 T 23-10-2018 IPR007410 Copper chaperone PCuAC APE_1722a 1472e5ded8c6f81fee146e0b74e36ce0 158 Gene3D G3DSA:2.60.40.1890 44 156 3.4E-11 T 23-10-2018 IPR036182 Copper chaperone PCuAC superfamily APE_1905 9574a8e734c718acc9d27bc79807d66e 203 Pfam PF01917 Archaebacterial flagellin 6 188 5.9E-37 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 APE_1905 9574a8e734c718acc9d27bc79807d66e 203 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 27 2.2E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal APE_1441.1 f47e14d756bf0af127a514e1899d992e 280 SUPERFAMILY SSF82861 24 104 6.02E-9 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 APE_1441.1 f47e14d756bf0af127a514e1899d992e 280 Gene3D G3DSA:3.30.70.100 171 265 4.8E-19 T 23-10-2018 APE_1441.1 f47e14d756bf0af127a514e1899d992e 280 Gene3D G3DSA:2.30.30.60 122 170 2.4E-12 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily APE_1441.1 f47e14d756bf0af127a514e1899d992e 280 SUPERFAMILY SSF82689 175 270 4.05E-22 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 APE_1441.1 f47e14d756bf0af127a514e1899d992e 280 Pfam PF00924 Mechanosensitive ion channel 65 260 1.3E-50 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 APE_1441.1 f47e14d756bf0af127a514e1899d992e 280 SUPERFAMILY SSF50182 106 171 1.5E-16 T 23-10-2018 IPR010920 LSM domain superfamily APE_1038.1 e5d22d00476572ebe50477cdcd09717a 136 SUPERFAMILY SSF53927 7 130 1.59E-42 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 APE_1038.1 e5d22d00476572ebe50477cdcd09717a 136 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 97 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 APE_1038.1 e5d22d00476572ebe50477cdcd09717a 136 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 101 8.0E-14 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain APE_1038.1 e5d22d00476572ebe50477cdcd09717a 136 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 8 130 2.0E-43 T 23-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 APE_1038.1 e5d22d00476572ebe50477cdcd09717a 136 Gene3D G3DSA:3.40.140.10 2 132 1.3E-49 T 23-10-2018 APE_0354.1 c1cec28b69070302793976c5356e99dd 192 PIRSF PIRSF002161 3 191 2.5E-55 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0354.1 c1cec28b69070302793976c5356e99dd 192 Pfam PF00281 Ribosomal protein L5 25 78 5.8E-21 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0354.1 c1cec28b69070302793976c5356e99dd 192 Gene3D G3DSA:3.30.1440.10 19 191 4.7E-65 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0354.1 c1cec28b69070302793976c5356e99dd 192 SUPERFAMILY SSF55282 25 189 3.3E-53 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0354.1 c1cec28b69070302793976c5356e99dd 192 Pfam PF00673 ribosomal L5P family C-terminus 83 180 2.8E-23 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0354.1 c1cec28b69070302793976c5356e99dd 192 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 24 192 39.792 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 Gene3D G3DSA:3.30.1490.70 77 253 6.9E-52 T 23-10-2018 APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 Gene3D G3DSA:3.30.470.30 103 206 6.9E-52 T 23-10-2018 APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 Gene3D G3DSA:3.30.70.3360 320 367 7.3E-22 T 23-10-2018 APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 SUPERFAMILY SSF56091 69 253 6.72E-31 T 23-10-2018 APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 Gene3D G3DSA:3.30.70.3350 257 374 7.3E-22 T 23-10-2018 APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 248 261 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 46 60 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 115 130 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 71 89 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 230 243 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 175 196 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 272 290 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 PRINTS PR01048 Hypothetical protein Y414 family signature 94 107 1.1E-41 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 14 385 1.2E-143 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family APE_1567.1 6fddc11f802ef2cbfaa50f47bc601caf 385 Pfam PF09414 RNA ligase 93 245 2.0E-14 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 Pfam PF00248 Aldo/keto reductase family 24 271 7.0E-54 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 Gene3D G3DSA:3.20.20.100 10 271 6.5E-78 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 PIRSF PIRSF000097 15 127 2.8E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 PIRSF PIRSF000097 121 271 4.1E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 PRINTS PR00069 Aldo-keto reductase signature 102 120 2.8E-13 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 PRINTS PR00069 Aldo-keto reductase signature 133 150 2.8E-13 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 PRINTS PR00069 Aldo-keto reductase signature 44 68 2.8E-13 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 SUPERFAMILY SSF51430 13 270 2.88E-75 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APE_1961 15c82a3b396b05ad65d3b9b696ea5d0f 272 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 Pfam PF00005 ABC transporter 23 165 3.6E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 307 3.6E-112 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 SUPERFAMILY SSF52540 7 229 2.28E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 Gene3D G3DSA:3.40.50.300 2 239 1.5E-68 T 23-10-2018 APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 SMART SM00382 31 214 1.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2579.1 b0cb55dd8a6716ce3ec23017e4721a00 330 Pfam PF13732 Domain of unknown function (DUF4162) 219 306 3.5E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 Pfam PF00271 Helicase conserved C-terminal domain 884 954 8.6E-10 T 23-10-2018 IPR001650 Helicase, C-terminal APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 SMART SM00487 589 807 6.6E-21 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 Pfam PF00270 DEAD/DEAH box helicase 614 769 2.3E-11 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 Gene3D G3DSA:3.40.50.300 570 787 1.0E-45 T 23-10-2018 APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 Gene3D G3DSA:3.40.50.300 853 998 2.8E-23 T 23-10-2018 APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 SMART SM00490 870 955 5.8E-17 T 23-10-2018 IPR001650 Helicase, C-terminal APE_1353.1 d69d1f25c477de2a341f959385a53997 1321 SUPERFAMILY SSF52540 644 974 2.41E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1746 08543d95eea3fc3fa2a3e61299a7159c 120 SUPERFAMILY SSF52080 5 119 1.44E-24 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily APE_1746 08543d95eea3fc3fa2a3e61299a7159c 120 ProSitePatterns PS00475 Ribosomal protein L15 signature. 67 97 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1746 08543d95eea3fc3fa2a3e61299a7159c 120 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 4 120 28.356 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea APE_1746 08543d95eea3fc3fa2a3e61299a7159c 120 Gene3D G3DSA:3.100.10.10 6 120 2.9E-33 T 23-10-2018 APE_1746 08543d95eea3fc3fa2a3e61299a7159c 120 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 20 118 4.8E-7 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P APE_1746 08543d95eea3fc3fa2a3e61299a7159c 120 ProSitePatterns PS01106 Ribosomal protein L18e signature. 35 52 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0975 95530488a7539497fa4a5b2d9a3cbba0 262 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 10 241 2.6E-87 T 23-10-2018 IPR018693 Protein of unknown function DUF2192 APE_1421.1 43eb08915d31eef8cd904ca01d974c77 375 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 2 342 18.233 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1421.1 43eb08915d31eef8cd904ca01d974c77 375 Pfam PF00146 NADH dehydrogenase 26 334 8.4E-78 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_2075 33982402be0d3a0d0bb9203cb8b4c159 464 Gene3D G3DSA:3.40.50.620 199 430 7.4E-38 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2075 33982402be0d3a0d0bb9203cb8b4c159 464 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 241 411 9.7E-32 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 APE_2075 33982402be0d3a0d0bb9203cb8b4c159 464 SUPERFAMILY SSF52402 215 402 1.74E-37 T 23-10-2018 APE_1366.1 6d7faa0925e8d41cd22ad5d6a8ad01e6 147 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 7 139 1.7E-33 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_1366.1 6d7faa0925e8d41cd22ad5d6a8ad01e6 147 SUPERFAMILY SSF52121 3 144 2.75E-38 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_1366.1 6d7faa0925e8d41cd22ad5d6a8ad01e6 147 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 7 141 1.7E-39 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_1366.1 6d7faa0925e8d41cd22ad5d6a8ad01e6 147 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 2 143 22.196 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_1366.1 6d7faa0925e8d41cd22ad5d6a8ad01e6 147 Gene3D G3DSA:3.40.50.960 2 144 3.6E-31 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SMART SM01073 7 92 7.8E-33 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Gene3D G3DSA:2.40.40.20 2 92 6.9E-30 T 23-10-2018 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 ProSitePatterns PS00674 AAA-protein family signature. 321 339 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Gene3D G3DSA:3.40.50.300 454 715 3.9E-109 T 23-10-2018 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SUPERFAMILY SSF50692 3 91 2.49E-24 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 7 91 3.9E-28 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 6 724 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SUPERFAMILY SSF52540 454 719 8.92E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Gene3D G3DSA:1.10.8.60 352 448 2.2E-32 T 23-10-2018 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Gene3D G3DSA:3.10.330.10 94 164 6.9E-7 T 23-10-2018 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SMART SM01072 108 170 1.4E-18 T 23-10-2018 IPR004201 CDC48, domain 2 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Gene3D G3DSA:1.10.8.60 629 701 3.9E-109 T 23-10-2018 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 2.0E-13 T 23-10-2018 IPR004201 CDC48, domain 2 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SMART SM00382 217 353 3.0E-27 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SMART SM00382 492 630 2.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Gene3D G3DSA:3.40.50.300 176 350 2.0E-74 T 23-10-2018 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SUPERFAMILY SSF52540 179 448 8.58E-78 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 ProSitePatterns PS00674 AAA-protein family signature. 598 616 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 SUPERFAMILY SSF54585 93 186 4.25E-21 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Pfam PF09336 Vps4 C terminal oligomerisation domain 682 718 5.5E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 496 627 4.0E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_1367 a4437b0786a64bd5e2a4bb41a1cca0a7 726 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 221 350 1.6E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_0048 f13d0aab5a62730e18507ddc0335a9ac 284 SUPERFAMILY SSF161098 17 272 6.64E-30 T 23-10-2018 IPR035906 MetI-like superfamily APE_0048 f13d0aab5a62730e18507ddc0335a9ac 284 Gene3D G3DSA:1.10.3720.10 60 283 3.7E-27 T 23-10-2018 IPR035906 MetI-like superfamily APE_0048 f13d0aab5a62730e18507ddc0335a9ac 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 277 7.4E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0048 f13d0aab5a62730e18507ddc0335a9ac 284 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 10 281 4.8E-63 T 23-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 SUPERFAMILY SSF55681 221 481 1.23E-63 T 23-10-2018 APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 SUPERFAMILY SSF46785 3 77 1.39E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 195 483 4.0E-91 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 Gene3D G3DSA:3.30.930.10 190 486 3.1E-88 T 23-10-2018 APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 Pfam PF01409 tRNA synthetases class II core domain (F) 219 482 4.2E-82 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 4 484 38.545 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 APE_2302.1 959689dd953d25eaedfbc26882c7399a 488 Gene3D G3DSA:1.10.10.10 1 105 1.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0415 2dde9477df88993f2c5722d65638f1c4 1188 Pfam PF04465 Protein of unknown function (DUF499) 119 1184 0.0 T 23-10-2018 IPR007555 Protein of unknown function DUF499 APE_0471.1 deeabb54f9eb90e534971f6f7f8eda7e 303 Gene3D G3DSA:3.40.50.300 3 235 6.8E-53 T 23-10-2018 APE_0471.1 deeabb54f9eb90e534971f6f7f8eda7e 303 SMART SM00382 29 207 3.9E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0471.1 deeabb54f9eb90e534971f6f7f8eda7e 303 SUPERFAMILY SSF52540 4 221 7.2E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0471.1 deeabb54f9eb90e534971f6f7f8eda7e 303 Pfam PF00005 ABC transporter 20 159 2.9E-19 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2533.1 7f42725a8c9c27e91582c9fde118acbf 688 Gene3D G3DSA:3.40.30.10 8 169 2.6E-57 T 23-10-2018 APE_2533.1 7f42725a8c9c27e91582c9fde118acbf 688 Gene3D G3DSA:1.50.10.10 210 336 5.0E-7 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 APE_2533.1 7f42725a8c9c27e91582c9fde118acbf 688 Pfam PF03190 Protein of unknown function, DUF255 11 160 6.5E-62 T 23-10-2018 IPR004879 Domain of unknown function DUF255 APE_2533.1 7f42725a8c9c27e91582c9fde118acbf 688 PIRSF PIRSF006402 2 687 7.5E-210 T 23-10-2018 IPR024705 Spermatogenesis-associated protein 20 APE_2533.1 7f42725a8c9c27e91582c9fde118acbf 688 SUPERFAMILY SSF48208 191 528 2.59E-57 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 APE_2533.1 7f42725a8c9c27e91582c9fde118acbf 688 SUPERFAMILY SSF52833 10 134 1.06E-28 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1761.1 b25a823a25c5576a436cb034fcdac9e5 186 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 5 144 3.0E-28 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 APE_1761.1 b25a823a25c5576a436cb034fcdac9e5 186 SUPERFAMILY SSF55154 6 156 5.89E-31 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 APE_1761.1 b25a823a25c5576a436cb034fcdac9e5 186 SMART SM01118 4 171 2.8E-18 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 APE_1761.1 b25a823a25c5576a436cb034fcdac9e5 186 Gene3D G3DSA:2.40.320.10 3 174 3.8E-34 T 23-10-2018 APE_1761.1 b25a823a25c5576a436cb034fcdac9e5 186 Pfam PF01928 CYTH domain 6 155 2.8E-27 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 APE_1761.1 b25a823a25c5576a436cb034fcdac9e5 186 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 36 140 5.0E-37 T 23-10-2018 APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 Pfam PF00005 ABC transporter 51 223 1.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 Gene3D G3DSA:3.40.50.300 17 375 1.0E-87 T 23-10-2018 APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 ProSitePatterns PS00211 ABC transporters family signature. 196 210 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 SUPERFAMILY SSF52540 20 295 9.59E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 275 336 3.7E-17 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 SMART SM00382 59 273 2.8E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1576 087e96ca692fccd949db3bf7ba8598d0 377 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 273 371 8.6E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1893.1 9416d4d0aa94d96f7c5513c764aeaae9 283 Gene3D G3DSA:3.40.190.10 53 273 6.2E-56 T 23-10-2018 APE_1893.1 9416d4d0aa94d96f7c5513c764aeaae9 283 SUPERFAMILY SSF53850 8 273 4.35E-54 T 23-10-2018 APE_1893.1 9416d4d0aa94d96f7c5513c764aeaae9 283 SMART SM00062 56 278 1.6E-40 T 23-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF APE_1893.1 9416d4d0aa94d96f7c5513c764aeaae9 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 57 274 7.8E-52 T 23-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF APE_1893.1 9416d4d0aa94d96f7c5513c764aeaae9 283 Gene3D G3DSA:3.40.190.10 144 237 6.2E-56 T 23-10-2018 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Hamap MF_00407 DNA ligase [lig]. 1 589 31.693 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 413 439 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Gene3D G3DSA:3.30.470.30 236 441 4.5E-72 T 23-10-2018 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Pfam PF04679 ATP dependent DNA ligase C terminal region 464 573 8.0E-26 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 58 589 7.2E-167 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Pfam PF04675 DNA ligase N terminus 2 188 5.7E-37 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 SUPERFAMILY SSF50249 447 591 1.37E-50 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Gene3D G3DSA:1.10.3260.10 1 235 1.1E-70 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Pfam PF01068 ATP dependent DNA ligase domain 239 439 6.4E-62 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 262 270 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 Gene3D G3DSA:2.40.50.140 442 601 5.6E-60 T 23-10-2018 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 SUPERFAMILY SSF117018 1 242 2.48E-63 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 APE_1094.1 832bc9a752ab8f4c3b1d837c1948c200 602 SUPERFAMILY SSF56091 234 439 1.61E-51 T 23-10-2018 APE_2390.1 8851a70403ebdc402b389d76119555d3 154 SUPERFAMILY SSF50249 14 138 2.06E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_2390.1 8851a70403ebdc402b389d76119555d3 154 Gene3D G3DSA:2.40.50.140 75 132 2.9E-10 T 23-10-2018 APE_2390.1 8851a70403ebdc402b389d76119555d3 154 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 78 133 5.0E-10 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal APE_2390.1 8851a70403ebdc402b389d76119555d3 154 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 37 64 8.0E-7 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal APE_2390.1 8851a70403ebdc402b389d76119555d3 154 Gene3D G3DSA:1.10.12.20 4 71 3.2E-14 T 23-10-2018 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 SMART SM01413 3 141 2.0E-83 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 Gene3D G3DSA:1.10.10.2700 1 152 6.0E-56 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 30 113 3.0E-44 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 150 36.413 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 ProSitePatterns PS00628 Ribosomal protein S19e signature. 89 108 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 Pfam PF01090 Ribosomal protein S19e 6 140 1.6E-52 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1090 d6403150b3f920a413ee2cc9b6443c06 153 SUPERFAMILY SSF46785 3 152 7.53E-53 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0793.1 67c04ae0511a97dfe788c09832362813 815 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 23-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 23 466 3.4E-131 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 Gene3D G3DSA:1.20.120.80 629 815 1.9E-38 T 23-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 Pfam PF00510 Cytochrome c oxidase subunit III 571 813 2.7E-20 T 23-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 192 211 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 131 143 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 163 181 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 14 39 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 61 84 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 221 242 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 88 112 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 2.8E-74 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 Gene3D G3DSA:1.20.210.10 2 526 1.0E-184 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 SUPERFAMILY SSF81442 11 519 7.33E-157 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0793.1 67c04ae0511a97dfe788c09832362813 815 SUPERFAMILY SSF81452 564 814 3.53E-42 T 23-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 SUPERFAMILY SSF64484 15 1155 0.0 T 23-10-2018 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF04561 RNA polymerase Rpb2, domain 2 200 376 2.2E-29 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Gene3D G3DSA:3.90.1110.10 202 366 9.7E-48 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF04567 RNA polymerase Rpb2, domain 5 641 673 1.8E-6 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF00562 RNA polymerase Rpb2, domain 6 689 1061 4.4E-125 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 553 1157 1.1E-300 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF04565 RNA polymerase Rpb2, domain 3 444 508 1.4E-25 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Gene3D G3DSA:3.90.1070.20 511 608 4.6E-17 T 23-10-2018 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Gene3D G3DSA:2.40.50.150 719 910 2.5E-135 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Gene3D G3DSA:3.90.1800.10 1048 1156 5.8E-41 T 23-10-2018 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Gene3D G3DSA:2.40.270.10 689 1046 2.5E-135 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF04566 RNA polymerase Rpb2, domain 4 553 620 4.5E-18 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF04563 RNA polymerase beta subunit 30 423 5.6E-45 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 ProSitePatterns PS01166 RNA polymerases beta chain signature. 914 926 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Pfam PF04560 RNA polymerase Rpb2, domain 7 1063 1153 5.4E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1856 c4dc66c629d0585e4e21b23d6954da93 1169 Gene3D G3DSA:3.90.1100.10 25 201 2.5E-10 T 23-10-2018 APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 124 8.3E-11 T 23-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 99 124 - T 23-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 Pfam PF13378 Enolase C-terminal domain-like 145 354 2.4E-34 T 23-10-2018 IPR029065 Enolase C-terminal domain-like APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 361 42.035 T 23-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 9 332 5.3E-101 T 23-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 SMART SM00922 142 234 7.2E-21 T 23-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 Gene3D G3DSA:3.30.390.10 13 361 1.3E-120 T 23-10-2018 IPR029017 Enolase-like, N-terminal APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 Gene3D G3DSA:3.20.20.120 117 348 1.3E-120 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 SUPERFAMILY SSF54826 2 125 6.79E-32 T 23-10-2018 APE_0712.1 76fb5dbf4bcad09bcacfc0f9e3f7db85 375 SUPERFAMILY SSF51604 114 366 6.29E-58 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily APE_2540.1 d139ab4fdd6e7a604992941c1940606a 151 SUPERFAMILY SSF55826 2 149 2.09E-36 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 APE_2540.1 d139ab4fdd6e7a604992941c1940606a 151 Gene3D G3DSA:3.90.960.10 1 151 4.7E-43 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 APE_2540.1 d139ab4fdd6e7a604992941c1940606a 151 Pfam PF04073 Aminoacyl-tRNA editing domain 22 140 2.8E-30 T 23-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 PRINTS PR00058 Ribosomal protein L5 signature 103 122 3.1E-12 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 PRINTS PR00058 Ribosomal protein L5 signature 1 12 3.1E-12 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 PRINTS PR00058 Ribosomal protein L5 signature 123 142 3.1E-12 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 43.78 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 97 3.5E-21 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 134 3.4E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 Pfam PF14204 Ribosomal L18 C-terminal region 142 203 1.9E-9 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 Gene3D G3DSA:3.30.420.100 1 199 1.9E-67 T 23-10-2018 APE_0347 ab8f44d417186a81b0c5119b939ff638 214 SUPERFAMILY SSF53137 4 195 3.4E-60 T 23-10-2018 APE_0113a 28d9e9f957c7014159a56ad7893c424e 50 SMART SM01377 3 50 4.2E-19 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 APE_0113a 28d9e9f957c7014159a56ad7893c424e 50 SUPERFAMILY SSF57829 1 49 2.56E-18 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APE_0113a 28d9e9f957c7014159a56ad7893c424e 50 Gene3D G3DSA:2.20.28.70 1 50 5.1E-23 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 APE_0113a 28d9e9f957c7014159a56ad7893c424e 50 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 7 50 18.08 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 APE_0113a 28d9e9f957c7014159a56ad7893c424e 50 Pfam PF01020 Ribosomal L40e family 5 49 4.9E-10 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 APE_0695.1 f069181e9174bb22294f8d8cc938e7c6 471 Pfam PF00437 Type II/IV secretion system protein 106 348 1.1E-39 T 23-10-2018 IPR001482 Type II/IV secretion system protein APE_0695.1 f069181e9174bb22294f8d8cc938e7c6 471 SUPERFAMILY SSF52540 227 467 2.81E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0695.1 f069181e9174bb22294f8d8cc938e7c6 471 SMART SM00382 226 362 2.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0695.1 f069181e9174bb22294f8d8cc938e7c6 471 Gene3D G3DSA:3.30.450.380 80 196 1.0E-25 T 23-10-2018 APE_0695.1 f069181e9174bb22294f8d8cc938e7c6 471 SUPERFAMILY SSF52540 88 390 1.41E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0695.1 f069181e9174bb22294f8d8cc938e7c6 471 Gene3D G3DSA:3.40.50.300 199 468 6.6E-68 T 23-10-2018 APE_0300.1 0d6519ecaa06a4bf94a398bd33ff31f0 419 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 267 334 5.7E-18 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_0300.1 0d6519ecaa06a4bf94a398bd33ff31f0 419 ProSitePatterns PS00211 ABC transporters family signature. 190 204 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0300.1 0d6519ecaa06a4bf94a398bd33ff31f0 419 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 269 336 2.9E-16 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_0300.1 0d6519ecaa06a4bf94a398bd33ff31f0 419 SMART SM00382 39 310 1.5E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0300.1 0d6519ecaa06a4bf94a398bd33ff31f0 419 SUPERFAMILY SSF52540 38 332 1.17E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0300.1 0d6519ecaa06a4bf94a398bd33ff31f0 419 Pfam PF00005 ABC transporter 31 218 1.4E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Gene3D G3DSA:3.90.1170.50 2 138 1.6E-48 T 23-10-2018 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Gene3D G3DSA:3.30.365.10 462 631 1.6E-152 T 23-10-2018 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 SUPERFAMILY SSF56003 130 780 1.31E-216 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Gene3D G3DSA:3.30.365.10 377 756 1.6E-152 T 23-10-2018 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 716 1.7E-186 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Gene3D G3DSA:3.30.365.10 195 291 3.5E-70 T 23-10-2018 APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 138 1.1E-29 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 SUPERFAMILY SSF54665 5 160 4.58E-52 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 SMART SM01008 22 138 4.3E-52 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APE_2216.1 dcb502f7b384f645d15c4928bc4389cd 785 Gene3D G3DSA:3.30.365.10 152 368 3.5E-70 T 23-10-2018 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 SUPERFAMILY SSF53187 14 348 1.83E-36 T 23-10-2018 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 Gene3D G3DSA:3.40.630.10 18 337 7.2E-72 T 23-10-2018 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 Gene3D G3DSA:3.30.70.360 164 262 7.2E-72 T 23-10-2018 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 10 347 30.197 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 Pfam PF07687 Peptidase dimerisation domain 162 232 5.9E-12 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 Pfam PF01546 Peptidase family M20/M25/M40 69 343 1.0E-20 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 SUPERFAMILY SSF55031 165 234 1.44E-10 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain APE_1467.1 a0e0c0d95421190c1596f8032b3fbf31 350 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 15 346 9.0E-68 T 23-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 APE_0681.1 0762962062086b34bb48bbd8bee6725a 128 Pfam PF14464 Prokaryotic homologs of the JAB domain 16 116 1.8E-15 T 23-10-2018 IPR028090 JAB domain, prokaryotic APE_0681.1 0762962062086b34bb48bbd8bee6725a 128 SUPERFAMILY SSF102712 12 122 2.35E-18 T 23-10-2018 APE_0681.1 0762962062086b34bb48bbd8bee6725a 128 Gene3D G3DSA:3.40.140.10 8 128 4.1E-21 T 23-10-2018 APE_2528.1 6ee7e02d604d180a0abb0fe1b680faad 682 SUPERFAMILY SSF53067 3 345 1.68E-6 T 23-10-2018 APE_2528.1 6ee7e02d604d180a0abb0fe1b680faad 682 Pfam PF01968 Hydantoinase/oxoprolinase 200 497 6.1E-102 T 23-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 APE_2528.1 6ee7e02d604d180a0abb0fe1b680faad 682 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 179 1.5E-48 T 23-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 Pfam PF00189 Ribosomal protein S3, C-terminal domain 101 184 9.3E-25 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 ProSitePatterns PS00548 Ribosomal protein S3 signature. 143 179 - T 23-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 Gene3D G3DSA:3.30.1140.32 89 245 9.2E-35 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 4 204 37.955 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 5 197 6.0E-87 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 SUPERFAMILY SSF54821 88 187 2.35E-25 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 Pfam PF07650 KH domain 18 84 8.6E-11 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 Gene3D G3DSA:3.30.300.20 2 86 3.2E-21 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta APE_0363 69147f3cf9b035841f23fee940f0cef9 246 SMART SM00322 40 106 0.0029 T 23-10-2018 IPR004087 K Homology domain GO:0003676 APE_0363 69147f3cf9b035841f23fee940f0cef9 246 SUPERFAMILY SSF54814 9 95 4.8E-20 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 1 489 30.206 T 23-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 PIRSF PIRSF006294 1 486 9.0E-125 T 23-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 Pfam PF01293 Phosphoenolpyruvate carboxykinase 63 446 1.2E-39 T 23-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 SUPERFAMILY SSF68923 18 172 6.8E-7 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 Gene3D G3DSA:3.90.228.20 312 482 6.6E-19 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 Gene3D G3DSA:2.170.8.10 245 306 1.3E-5 T 23-10-2018 APE_0033.1 6c34c0f7fd0b546f2b0ffb56f2057d57 489 SUPERFAMILY SSF53795 198 479 2.75E-54 T 23-10-2018 APE_1179.1 de5e82fa8905fa3e36bafd9b857f534f 300 Gene3D G3DSA:3.40.50.720 2 294 2.4E-82 T 23-10-2018 APE_1179.1 de5e82fa8905fa3e36bafd9b857f534f 300 SUPERFAMILY SSF51735 2 294 5.15E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1179.1 de5e82fa8905fa3e36bafd9b857f534f 300 Pfam PF04321 RmlD substrate binding domain 2 294 1.3E-85 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 APE_1179.1 de5e82fa8905fa3e36bafd9b857f534f 300 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 293 3.5E-104 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 APE_2104.1 be6ca631e970b497f7c7d9879ec3a5d8 280 Gene3D G3DSA:3.20.20.150 9 280 1.8E-41 T 23-10-2018 APE_2104.1 be6ca631e970b497f7c7d9879ec3a5d8 280 Pfam PF01261 Xylose isomerase-like TIM barrel 24 228 2.0E-23 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain APE_2104.1 be6ca631e970b497f7c7d9879ec3a5d8 280 SUPERFAMILY SSF51658 4 278 1.57E-57 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily APE_2104.1 be6ca631e970b497f7c7d9879ec3a5d8 280 SMART SM00518 1 276 1.0E-113 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 APE_1404.1 8f6fbb6cd59d0a80fd614e69cbd2dffa 419 Gene3D G3DSA:3.65.10.10 12 407 1.6E-74 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APE_1404.1 8f6fbb6cd59d0a80fd614e69cbd2dffa 419 Gene3D G3DSA:3.65.10.10 20 225 1.6E-74 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 APE_1404.1 8f6fbb6cd59d0a80fd614e69cbd2dffa 419 SUPERFAMILY SSF55205 3 415 2.45E-79 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 APE_1404.1 8f6fbb6cd59d0a80fd614e69cbd2dffa 419 PIRSF PIRSF000505 1 419 4.3E-113 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 APE_1404.1 8f6fbb6cd59d0a80fd614e69cbd2dffa 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 409 1.5E-58 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 APE_2447 887680e7c0dd7160c2c12c5b9117a155 142 Pfam PF05425 Copper resistance protein D 48 138 3.6E-13 T 23-10-2018 IPR008457 Copper resistance protein D GO:0016021 APE_0916.1 0e8ee402250aa3f521c81b9f02e4e1a3 290 PIRSF PIRSF001439 5 287 1.2E-44 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 APE_0916.1 0e8ee402250aa3f521c81b9f02e4e1a3 290 Gene3D G3DSA:3.40.50.720 108 262 7.4E-54 T 23-10-2018 APE_0916.1 0e8ee402250aa3f521c81b9f02e4e1a3 290 SUPERFAMILY SSF51735 5 282 1.97E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0916.1 0e8ee402250aa3f521c81b9f02e4e1a3 290 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 35 280 4.4E-31 T 23-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 APE_0916.1 0e8ee402250aa3f521c81b9f02e4e1a3 290 Gene3D G3DSA:3.30.1780.10 3 279 7.4E-54 T 23-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 APE_2431.1 c23016191b056587aac45f269563d091 194 Pfam PF02926 THUMP domain 28 162 1.3E-18 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_2431.1 c23016191b056587aac45f269563d091 194 SUPERFAMILY SSF143437 31 158 5.58E-7 T 23-10-2018 APE_1310 03df0a1f0ea531438e5fe204b969c984 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 519 5.5E-9 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APE_1310 03df0a1f0ea531438e5fe204b969c984 529 Gene3D G3DSA:3.40.50.12780 38 439 4.9E-68 T 23-10-2018 APE_1310 03df0a1f0ea531438e5fe204b969c984 529 SUPERFAMILY SSF56801 21 520 4.06E-90 T 23-10-2018 APE_1310 03df0a1f0ea531438e5fe204b969c984 529 Gene3D G3DSA:3.30.300.30 442 521 9.6E-14 T 23-10-2018 APE_1310 03df0a1f0ea531438e5fe204b969c984 529 Pfam PF00501 AMP-binding enzyme 58 447 3.4E-57 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_1509.1 8e66352c5de39ebc780fcc8b54c61eed 153 Gene3D G3DSA:3.30.1330.80 5 151 1.6E-28 T 23-10-2018 APE_1509.1 8e66352c5de39ebc780fcc8b54c61eed 153 SUPERFAMILY SSF117856 7 144 4.45E-24 T 23-10-2018 APE_1509.1 8e66352c5de39ebc780fcc8b54c61eed 153 Pfam PF03479 Domain of unknown function (DUF296) 11 127 3.9E-16 T 23-10-2018 IPR005175 PPC domain APE_2283.1 732993b22b190e544e31311791f031bb 206 SUPERFAMILY SSF56300 6 204 3.23E-46 T 23-10-2018 APE_2283.1 732993b22b190e544e31311791f031bb 206 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 191 3.1E-17 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 APE_2283.1 732993b22b190e544e31311791f031bb 206 Gene3D G3DSA:3.60.21.10 27 205 1.9E-19 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 Gene3D G3DSA:3.30.310.10 30 112 1.1E-27 T 23-10-2018 IPR012295 TBP domain superfamily APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 SUPERFAMILY SSF55945 110 196 1.19E-31 T 23-10-2018 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 143 192 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 23 101 2.5E-26 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 114 194 1.9E-31 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 SUPERFAMILY SSF55945 19 106 3.61E-27 T 23-10-2018 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 PRINTS PR00686 Transcription initiation factor TFIID signature 25 40 2.4E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 PRINTS PR00686 Transcription initiation factor TFIID signature 116 132 2.4E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 PRINTS PR00686 Transcription initiation factor TFIID signature 49 68 2.4E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 PRINTS PR00686 Transcription initiation factor TFIID signature 68 86 2.4E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 PRINTS PR00686 Transcription initiation factor TFIID signature 139 154 2.4E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 PRINTS PR00686 Transcription initiation factor TFIID signature 158 174 2.4E-44 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 Gene3D G3DSA:3.30.310.10 113 201 1.7E-35 T 23-10-2018 IPR012295 TBP domain superfamily APE_1862.1 68facfd7bd8cf71adf13f05fd2bb39c9 203 Hamap MF_00408 TATA-box-binding protein [tbp]. 19 198 37.808 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 APE_0423.1 0c88e8d88d5e7140f9b30c2ecdf96a88 246 Gene3D G3DSA:3.20.20.140 1 245 3.8E-41 T 23-10-2018 APE_0423.1 0c88e8d88d5e7140f9b30c2ecdf96a88 246 PIRSF PIRSF005902 1 246 6.3E-44 T 23-10-2018 IPR001130 TatD family GO:0016788 APE_0423.1 0c88e8d88d5e7140f9b30c2ecdf96a88 246 Pfam PF01026 TatD related DNase 5 243 2.7E-45 T 23-10-2018 IPR001130 TatD family GO:0016788 APE_0423.1 0c88e8d88d5e7140f9b30c2ecdf96a88 246 SUPERFAMILY SSF51556 4 245 2.66E-45 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_0423.1 0c88e8d88d5e7140f9b30c2ecdf96a88 246 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 244 6.3E-62 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 SUPERFAMILY SSF54849 155 411 2.84E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 Gene3D G3DSA:3.50.7.10 224 375 4.6E-212 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 15 532 3.0E-235 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 SUPERFAMILY SSF52029 219 385 4.4E-61 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 96 104 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 47 59 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 414 426 2.4E-28 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 380 402 2.4E-28 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 66 84 2.4E-28 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 96 115 2.4E-28 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 44 60 2.4E-28 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 Gene3D G3DSA:3.30.260.10 153 411 4.6E-212 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 68 84 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 42 533 2.2E-184 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 SUPERFAMILY SSF48592 24 532 3.92E-90 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily APE_2072.1 e9b40f980518ee004b51422f255c53c9 548 Gene3D G3DSA:1.10.560.10 35 529 4.6E-212 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily APE_1087a acf801b56239eaf504d588d3caca1518 51 SUPERFAMILY SSF48662 4 51 4.71E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily APE_1087a acf801b56239eaf504d588d3caca1518 51 Pfam PF00832 Ribosomal L39 protein 9 50 5.2E-19 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1087a acf801b56239eaf504d588d3caca1518 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 18.527 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1087a acf801b56239eaf504d588d3caca1518 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087a acf801b56239eaf504d588d3caca1518 51 Gene3D G3DSA:1.10.1620.10 1 51 4.7E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily APE_2547 64104b4225992387a3b155e5c9cba6b0 215 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 213 24.904 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 APE_2547 64104b4225992387a3b155e5c9cba6b0 215 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 202 2.5E-9 T 23-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 APE_2547 64104b4225992387a3b155e5c9cba6b0 215 SUPERFAMILY SSF51366 3 204 5.18E-22 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_2547 64104b4225992387a3b155e5c9cba6b0 215 Gene3D G3DSA:3.20.20.70 2 213 1.7E-26 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1971.1 dae117d1c718d21675d12ff2778aab93 450 Gene3D G3DSA:3.40.50.300 220 313 5.8E-7 T 23-10-2018 APE_1971.1 dae117d1c718d21675d12ff2778aab93 450 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 237 298 2.2E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain APE_1971.1 dae117d1c718d21675d12ff2778aab93 450 Gene3D G3DSA:3.40.50.720 4 131 2.1E-8 T 23-10-2018 APE_1971.1 dae117d1c718d21675d12ff2778aab93 450 SUPERFAMILY SSF52540 124 298 1.55E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.7E-9 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.7E-9 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.7E-9 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.7E-9 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 SUPERFAMILY SSF51735 2 128 9.6E-26 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 Pfam PF02254 TrkA-N domain 3 117 2.1E-24 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 Gene3D G3DSA:3.30.70.1450 143 220 2.8E-5 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 SUPERFAMILY SSF116726 145 219 6.28E-6 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 APE_2456.1 b1848a0c8a450806a490e009bb52aa75 220 Gene3D G3DSA:3.40.50.720 1 132 2.8E-29 T 23-10-2018 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 SUPERFAMILY SSF50249 61 145 4.44E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 SMART SM00322 146 210 1.8E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 Pfam PF15985 KH domain 149 196 3.9E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 Gene3D G3DSA:2.40.50.140 60 148 2.0E-22 T 23-10-2018 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 SMART SM00316 65 139 8.6E-7 T 23-10-2018 IPR022967 RNA-binding domain, S1 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 234 33.824 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 Gene3D G3DSA:3.30.1370.10 149 235 1.6E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APE_1448 ca07cca1f786d56681bfbc82430cfa28 235 SUPERFAMILY SSF54791 150 228 3.16E-15 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APE_2261.1 722bc14ea9261bf821902348e96685e5 316 SMART SM00382 32 230 8.6E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2261.1 722bc14ea9261bf821902348e96685e5 316 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 231 314 7.9E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_2261.1 722bc14ea9261bf821902348e96685e5 316 SUPERFAMILY SSF52540 3 251 1.25E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2261.1 722bc14ea9261bf821902348e96685e5 316 Gene3D G3DSA:3.40.50.300 1 316 2.1E-100 T 23-10-2018 APE_2261.1 722bc14ea9261bf821902348e96685e5 316 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 295 2.7E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_2261.1 722bc14ea9261bf821902348e96685e5 316 Pfam PF00005 ABC transporter 24 180 1.7E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2261.1 722bc14ea9261bf821902348e96685e5 316 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 347 354 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 Gene3D G3DSA:3.30.70.420 137 252 4.8E-128 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 194 208 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 Gene3D G3DSA:3.90.770.10 83 402 4.8E-128 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 SUPERFAMILY SSF55035 137 252 1.57E-41 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 42 415 4.6E-133 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 13 415 1.6E-152 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 SUPERFAMILY SSF56542 13 404 1.15E-90 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 103 123 1.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 283 309 1.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 335 356 1.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 192 210 1.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 72 93 1.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_1869 2c9c8b92dc8051bea6d6aa1582758d56 421 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 233 258 1.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 APE_0416.1 e5db6da3ecc198e81903cd200ffaecc8 1004 PIRSF PIRSF009427 1 1004 0.0 T 23-10-2018 IPR014455 DNA methylase, N-6 adenine-specific, MK1259 type APE_0416.1 e5db6da3ecc198e81903cd200ffaecc8 1004 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 574 580 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APE_0416.1 e5db6da3ecc198e81903cd200ffaecc8 1004 SUPERFAMILY SSF53335 88 599 9.4E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0416.1 e5db6da3ecc198e81903cd200ffaecc8 1004 Pfam PF06634 Protein of unknown function (DUF1156) 15 62 1.1E-9 T 23-10-2018 IPR009537 Domain of unknown function DUF1156 APE_0416.1 e5db6da3ecc198e81903cd200ffaecc8 1004 SUPERFAMILY SSF53335 558 781 1.52E-11 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0416.1 e5db6da3ecc198e81903cd200ffaecc8 1004 Gene3D G3DSA:3.40.50.150 69 170 3.5E-5 T 23-10-2018 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 Gene3D G3DSA:3.30.70.20 176 241 1.4E-68 T 23-10-2018 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 22 270 3.5E-15 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 SUPERFAMILY SSF55257 6 280 1.65E-24 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 32 72 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 7 280 33.768 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 51 166 4.1E-26 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 SUPERFAMILY SSF56553 43 167 2.09E-28 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 SMART SM00662 18 277 2.7E-91 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 Gene3D G3DSA:2.170.120.12 44 165 1.4E-68 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1744.1 c61c22a39bec6259e7c6fb0e3a9bbb55 286 Gene3D G3DSA:3.30.1360.10 18 274 1.4E-68 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1451.1 803afdc3b23277b4d77df5bb84db7876 153 Gene3D G3DSA:3.30.1440.10 1 152 2.2E-42 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1451.1 803afdc3b23277b4d77df5bb84db7876 153 SUPERFAMILY SSF55282 6 143 2.18E-39 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1451.1 803afdc3b23277b4d77df5bb84db7876 153 Pfam PF01877 RNA binding 7 125 6.2E-37 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 APE_0401.1 9d0ea05a48ea66a02c1e5165902492f1 225 PIRSF PIRSF005650 1 225 4.7E-45 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 APE_0401.1 9d0ea05a48ea66a02c1e5165902492f1 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 4 220 8.2E-56 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 APE_0401.1 9d0ea05a48ea66a02c1e5165902492f1 225 SUPERFAMILY SSF53633 4 223 1.44E-32 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_0401.1 9d0ea05a48ea66a02c1e5165902492f1 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 2 225 32.395 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 APE_0401.1 9d0ea05a48ea66a02c1e5165902492f1 225 Pfam PF00696 Amino acid kinase family 4 203 6.6E-21 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APE_0401.1 9d0ea05a48ea66a02c1e5165902492f1 225 Gene3D G3DSA:3.40.1160.10 3 224 4.5E-40 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Gene3D G3DSA:3.30.70.240 471 723 9.6E-86 T 23-10-2018 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 4 724 3.1E-286 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SUPERFAMILY SSF50447 261 379 9.56E-27 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Pfam PF03144 Elongation factor Tu domain 2 307 373 2.8E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 PRINTS PR00315 GTP-binding elongation factor signature 67 75 5.2E-17 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 PRINTS PR00315 GTP-binding elongation factor signature 143 152 5.2E-17 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 PRINTS PR00315 GTP-binding elongation factor signature 107 118 5.2E-17 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 PRINTS PR00315 GTP-binding elongation factor signature 23 36 5.2E-17 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 PRINTS PR00315 GTP-binding elongation factor signature 91 101 5.2E-17 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SMART SM00889 510 624 6.6E-23 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SUPERFAMILY SSF54980 629 722 5.28E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Pfam PF14492 Elongation Factor G, domain II 391 463 2.1E-23 T 23-10-2018 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SUPERFAMILY SSF54980 392 468 2.41E-21 T 23-10-2018 IPR035647 EF-G domain III/V-like APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 20 154 2.4E-24 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Pfam PF00679 Elongation factor G C-terminus 627 712 3.2E-22 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Hamap MF_00054_A Elongation factor G [fusA]. 2 730 42.93 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SUPERFAMILY SSF54211 468 628 1.37E-54 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Gene3D G3DSA:2.40.30.10 261 391 1.1E-19 T 23-10-2018 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Pfam PF00009 Elongation factor Tu GTP binding domain 20 259 8.8E-65 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Gene3D G3DSA:3.40.50.300 7 223 2.9E-74 T 23-10-2018 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Gene3D G3DSA:3.30.230.10 477 725 9.6E-86 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Gene3D G3DSA:3.30.70.870 393 470 9.5E-25 T 23-10-2018 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 Pfam PF03764 Elongation factor G, domain IV 516 622 3.1E-31 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SMART SM00838 626 713 9.5E-41 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like APE_1432 ac417fe22ea241c82fcb36f62ab878ca 736 SUPERFAMILY SSF52540 10 265 8.1E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 PRINTS PR01047 Threonyl-tRNA synthetase signature 262 290 2.6E-16 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 PRINTS PR01047 Threonyl-tRNA synthetase signature 107 135 2.6E-16 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 PRINTS PR01047 Threonyl-tRNA synthetase signature 306 319 2.6E-16 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 345 2.6E-16 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 97 327 1.5E-44 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 SUPERFAMILY SSF52954 330 422 2.84E-8 T 23-10-2018 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 Gene3D G3DSA:3.40.50.800 331 471 2.7E-69 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 SUPERFAMILY SSF55681 35 324 7.26E-54 T 23-10-2018 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 Gene3D G3DSA:3.30.930.10 1 330 6.3E-99 T 23-10-2018 APE_0809.1 d4e62007c84f0dec227d81420e7d2299 471 Pfam PF03129 Anticodon binding domain 340 430 2.0E-8 T 23-10-2018 IPR004154 Anticodon-binding APE_0986.1 6f39ee326c9e5f7cb815d05976007233 238 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 15 227 2.9E-44 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_0986.1 6f39ee326c9e5f7cb815d05976007233 238 SUPERFAMILY SSF55821 12 227 3.2E-52 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily APE_0986.1 6f39ee326c9e5f7cb815d05976007233 238 Gene3D G3DSA:3.90.870.10 10 235 1.6E-56 T 23-10-2018 APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 SUPERFAMILY SSF55021 55 131 1.43E-10 T 23-10-2018 APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 Gene3D G3DSA:2.10.260.10 3 46 1.4E-10 T 23-10-2018 APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 Pfam PF02381 MraZ protein, putative antitoxin-like 8 41 4.7E-5 T 23-10-2018 IPR020603 MraZ domain APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 37 1.1E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 SMART SM00966 8 55 5.8E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 Pfam PF01842 ACT domain 59 125 2.4E-8 T 23-10-2018 IPR002912 ACT domain APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 Gene3D G3DSA:3.30.70.260 55 136 3.2E-10 T 23-10-2018 APE_0381.1 e0e0520848e3b4cd9098540bc0c4fb04 142 SUPERFAMILY SSF89447 5 41 4.19E-9 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily APE_2017 62b74c934910e076bf468c3beb782962 512 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 2 494 41.428 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 APE_2017 62b74c934910e076bf468c3beb782962 512 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 2 334 4.3E-70 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APE_2017 62b74c934910e076bf468c3beb782962 512 Gene3D G3DSA:3.20.20.105 1 353 1.7E-101 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APE_2017 62b74c934910e076bf468c3beb782962 512 Pfam PF01702 Queuine tRNA-ribosyltransferase 104 327 5.3E-42 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APE_2017 62b74c934910e076bf468c3beb782962 512 SUPERFAMILY SSF51713 2 351 6.93E-103 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 APE_2017 62b74c934910e076bf468c3beb782962 512 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 2 451 1.8E-117 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 APE_0127 433475798b2bf36d85fcc5da6148f246 314 PIRSF PIRSF002849 2 314 7.8E-123 T 23-10-2018 APE_0127 433475798b2bf36d85fcc5da6148f246 314 Gene3D G3DSA:3.40.50.300 27 191 2.6E-44 T 23-10-2018 APE_0127 433475798b2bf36d85fcc5da6148f246 314 SUPERFAMILY SSF52540 13 297 8.07E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0127 433475798b2bf36d85fcc5da6148f246 314 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 173 2.0E-58 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 APE_0127 433475798b2bf36d85fcc5da6148f246 314 Gene3D G3DSA:1.10.8.300 205 311 1.6E-26 T 23-10-2018 APE_0127 433475798b2bf36d85fcc5da6148f246 314 SMART SM00382 43 182 1.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2006.1 d8eb1e18f80937978964739de3c6314a 183 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 62 179 7.0E-55 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 APE_2006.1 d8eb1e18f80937978964739de3c6314a 183 SUPERFAMILY SSF75217 9 180 6.8E-62 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_2006.1 d8eb1e18f80937978964739de3c6314a 183 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 9 182 39.714 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 APE_2006.1 d8eb1e18f80937978964739de3c6314a 183 PIRSF PIRSF016123 7 183 7.0E-82 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 APE_2006.1 d8eb1e18f80937978964739de3c6314a 183 Gene3D G3DSA:3.40.1280.10 7 183 1.0E-62 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APE_2006.1 d8eb1e18f80937978964739de3c6314a 183 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 62 179 4.8E-44 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 Gene3D G3DSA:3.90.180.10 13 336 5.7E-130 T 23-10-2018 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 Gene3D G3DSA:3.40.50.720 154 293 5.7E-130 T 23-10-2018 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 SUPERFAMILY SSF51735 145 312 7.89E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_2239.1 fe3018f83e30dbf299188c953871da46 344 Pfam PF00107 Zinc-binding dehydrogenase 182 307 6.0E-30 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 SMART SM00829 11 342 6.7E-4 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 136 2.6E-30 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APE_2239.1 fe3018f83e30dbf299188c953871da46 344 SUPERFAMILY SSF50129 2 177 2.99E-53 T 23-10-2018 IPR011032 GroES-like superfamily APE_1538.1 c533fb8828b471d6b89df2217907a275 223 SUPERFAMILY SSF51351 2 220 8.25E-37 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_1538.1 c533fb8828b471d6b89df2217907a275 223 Pfam PF05690 Thiazole biosynthesis protein ThiG 165 221 3.9E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 APE_1538.1 c533fb8828b471d6b89df2217907a275 223 ProSitePatterns PS00171 Triosephosphate isomerase active site. 137 147 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_1538.1 c533fb8828b471d6b89df2217907a275 223 Gene3D G3DSA:3.20.20.70 1 222 8.3E-72 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1538.1 c533fb8828b471d6b89df2217907a275 223 Pfam PF00121 Triosephosphate isomerase 4 118 1.1E-4 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_1538.1 c533fb8828b471d6b89df2217907a275 223 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 2 220 37.131 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 APE_1538.1 c533fb8828b471d6b89df2217907a275 223 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 207 1.0E-39 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_1849 8224fe189abcd4410c198c831080def5 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 2.3E-82 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1849 8224fe189abcd4410c198c831080def5 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 42.493 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea APE_1849 8224fe189abcd4410c198c831080def5 147 SUPERFAMILY SSF50249 23 147 1.88E-34 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1849 8224fe189abcd4410c198c831080def5 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1849 8224fe189abcd4410c198c831080def5 147 Gene3D G3DSA:2.40.50.140 28 147 2.2E-48 T 23-10-2018 APE_1849 8224fe189abcd4410c198c831080def5 147 PIRSF PIRSF002133 19 147 4.1E-35 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1849 8224fe189abcd4410c198c831080def5 147 Pfam PF00164 Ribosomal protein S12/S23 35 146 9.7E-47 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0316.1 18f0db2adcd370d1f10cf761d8738e4b 218 SUPERFAMILY SSF52768 7 208 6.66E-60 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily APE_0316.1 18f0db2adcd370d1f10cf761d8738e4b 218 ProSitePatterns PS01053 Arginase family signature. 139 160 - T 23-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 APE_0316.1 18f0db2adcd370d1f10cf761d8738e4b 218 Gene3D G3DSA:3.40.800.10 1 211 1.6E-59 T 23-10-2018 APE_0316.1 18f0db2adcd370d1f10cf761d8738e4b 218 PIRSF PIRSF036979 1 211 1.2E-58 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 APE_0316.1 18f0db2adcd370d1f10cf761d8738e4b 218 Pfam PF00491 Arginase family 3 206 1.3E-55 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 APE_1765.1 8d07bf7d7e47e14f3efe36115a340fdb 375 Pfam PF01070 FMN-dependent dehydrogenase 177 335 2.3E-13 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 APE_1765.1 8d07bf7d7e47e14f3efe36115a340fdb 375 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 8 342 1.7E-112 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 APE_1765.1 8d07bf7d7e47e14f3efe36115a340fdb 375 PIRSF PIRSF003314 3 354 4.0E-128 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 APE_1765.1 8d07bf7d7e47e14f3efe36115a340fdb 375 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 5 344 39.422 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 APE_1765.1 8d07bf7d7e47e14f3efe36115a340fdb 375 SUPERFAMILY SSF51395 28 360 4.03E-70 T 23-10-2018 APE_1765.1 8d07bf7d7e47e14f3efe36115a340fdb 375 Gene3D G3DSA:3.20.20.70 3 366 3.2E-119 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 542 2.1E-154 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 Pfam PF08264 Anticodon-binding domain of tRNA 422 560 7.5E-9 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 SUPERFAMILY SSF52374 3 385 1.76E-96 T 23-10-2018 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 Pfam PF09334 tRNA synthetases class I (M) 4 398 5.6E-153 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 Gene3D G3DSA:1.10.730.10 381 546 1.4E-38 T 23-10-2018 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 3.8E-28 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.8E-28 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.8E-28 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 3.8E-28 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 385 396 3.8E-28 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 PRINTS PR01041 Methionyl-tRNA synthetase signature 291 306 3.8E-28 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 SUPERFAMILY SSF57770 139 173 1.22E-12 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 Gene3D G3DSA:2.20.28.20 139 173 1.0E-152 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 Gene3D G3DSA:3.40.50.620 5 380 1.0E-152 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 SUPERFAMILY SSF47323 388 566 6.92E-33 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1129 7490767f59d2ade78191b8e09c17c3a3 572 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 554 40.05 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 Gene3D G3DSA:3.50.50.60 5 382 7.9E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 Pfam PF01266 FAD dependent oxidoreductase 101 335 4.1E-10 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 SUPERFAMILY SSF54373 180 286 5.1E-13 T 23-10-2018 APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 Pfam PF01946 Thi4 family 8 56 3.1E-8 T 23-10-2018 APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 SUPERFAMILY SSF51905 9 377 2.35E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.0E-9 T 23-10-2018 APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 354 2.0E-9 T 23-10-2018 APE_2421 eb1cc1c0a536ac16236fc25d49514485 436 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 11 33 2.0E-9 T 23-10-2018 APE_0450a 85635794741480cd2ce4218e9407c213 64 Gene3D G3DSA:2.30.30.610 6 62 9.4E-28 T 23-10-2018 IPR038647 Cren7 superfamily APE_0450a 85635794741480cd2ce4218e9407c213 64 Pfam PF11520 Chromatin protein Cren7 8 61 1.5E-30 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 APE_0450a 85635794741480cd2ce4218e9407c213 64 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 3 61 21.256 T 23-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 APE_0212.1 3d1d93f17c693f5613080959721ee6d8 402 Gene3D G3DSA:3.30.830.10 214 384 5.0E-12 T 23-10-2018 APE_0212.1 3d1d93f17c693f5613080959721ee6d8 402 SUPERFAMILY SSF63411 217 379 3.49E-11 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APE_0212.1 3d1d93f17c693f5613080959721ee6d8 402 Pfam PF05193 Peptidase M16 inactive domain 166 341 9.5E-20 T 23-10-2018 IPR007863 Peptidase M16, C-terminal APE_0212.1 3d1d93f17c693f5613080959721ee6d8 402 Pfam PF00675 Insulinase (Peptidase family M16) 22 158 2.2E-20 T 23-10-2018 IPR011765 Peptidase M16, N-terminal APE_0212.1 3d1d93f17c693f5613080959721ee6d8 402 SUPERFAMILY SSF63411 5 203 3.14E-41 T 23-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 APE_0212.1 3d1d93f17c693f5613080959721ee6d8 402 Gene3D G3DSA:3.30.830.10 2 209 3.1E-43 T 23-10-2018 APE_0800.1 360d840c75fb3480ed919cf9beef3004 360 Gene3D G3DSA:3.50.50.60 167 327 3.2E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0800.1 360d840c75fb3480ed919cf9beef3004 360 Pfam PF01266 FAD dependent oxidoreductase 5 326 1.3E-20 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APE_0800.1 360d840c75fb3480ed919cf9beef3004 360 SUPERFAMILY SSF51905 4 343 1.94E-18 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0800.1 360d840c75fb3480ed919cf9beef3004 360 Gene3D G3DSA:3.30.9.10 197 287 3.2E-15 T 23-10-2018 APE_0800.1 360d840c75fb3480ed919cf9beef3004 360 Gene3D G3DSA:3.50.50.60 2 95 5.9E-10 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_2551 7fd7a65c978038d933364caadd377599 345 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 14 340 5.4E-128 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 APE_2551 7fd7a65c978038d933364caadd377599 345 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 11 341 37.041 T 23-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 APE_2551 7fd7a65c978038d933364caadd377599 345 SUPERFAMILY SSF52418 81 342 1.7E-84 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 APE_2551 7fd7a65c978038d933364caadd377599 345 Gene3D G3DSA:1.20.970.10 12 75 9.4E-16 T 23-10-2018 APE_2551 7fd7a65c978038d933364caadd377599 345 Gene3D G3DSA:3.40.1030.10 79 344 3.3E-93 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 APE_2551 7fd7a65c978038d933364caadd377599 345 Pfam PF02885 Glycosyl transferase family, helical bundle domain 12 72 1.4E-10 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 APE_2551 7fd7a65c978038d933364caadd377599 345 Pfam PF00591 Glycosyl transferase family, a/b domain 81 330 5.2E-82 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 APE_2551 7fd7a65c978038d933364caadd377599 345 SUPERFAMILY SSF47648 13 75 3.4E-13 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 133 5.4E-37 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Gene3D G3DSA:3.40.120.10 5 144 6.8E-39 T 23-10-2018 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 SUPERFAMILY SSF53738 156 251 1.02E-20 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 SUPERFAMILY SSF55957 356 459 1.7E-17 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 250 4.4E-16 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 6.2E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 6.2E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 6.2E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 6.2E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 363 2.4E-4 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 SUPERFAMILY SSF53738 6 180 7.06E-37 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Gene3D G3DSA:3.40.120.10 173 355 4.0E-31 T 23-10-2018 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 406 447 1.6E-8 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 SUPERFAMILY SSF53738 262 362 1.37E-10 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Gene3D G3DSA:3.40.120.10 257 359 4.0E-31 T 23-10-2018 APE_2433.1 32c5ab116beb44ea95bf360e6f74d138 489 Gene3D G3DSA:3.30.310.50 379 457 8.8E-18 T 23-10-2018 APE_0283a 17346b988e321fa1b868bab6ba24a733 40 Pfam PF01954 Protein of unknown function DUF104 6 37 1.4E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_0283a 17346b988e321fa1b868bab6ba24a733 40 SUPERFAMILY SSF141694 6 38 2.88E-11 T 23-10-2018 APE_0283a 17346b988e321fa1b868bab6ba24a733 40 Gene3D G3DSA:4.10.1150.10 5 40 4.3E-9 T 23-10-2018 IPR024069 AF2212-like domain superfamily APE_0069.1 4a82f2a234a1feceff26b6715b955e19 159 SUPERFAMILY SSF51283 18 157 8.24E-31 T 23-10-2018 IPR036157 dUTPase-like superfamily APE_0069.1 4a82f2a234a1feceff26b6715b955e19 159 Hamap MF_00635 Probable deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 1 156 32.503 T 23-10-2018 IPR023537 Deoxyuridine triphosphate nucleotidohydrolase, archaeal GO:0004170 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 APE_0069.1 4a82f2a234a1feceff26b6715b955e19 159 Pfam PF00692 dUTPase 70 149 4.9E-10 T 23-10-2018 IPR029054 dUTPase-like APE_0069.1 4a82f2a234a1feceff26b6715b955e19 159 Gene3D G3DSA:2.70.40.10 11 158 4.1E-23 T 23-10-2018 IPR036157 dUTPase-like superfamily APE_0080.1 d5077358872a80b86a519e086a51bfa1 673 SMART SM00382 187 616 1.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0080.1 d5077358872a80b86a519e086a51bfa1 673 SUPERFAMILY SSF52540 128 615 1.21E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0080.1 d5077358872a80b86a519e086a51bfa1 673 Pfam PF09378 HAS barrel domain 18 122 1.1E-12 T 23-10-2018 IPR018538 Helicase HerA, barrel domain APE_0080.1 d5077358872a80b86a519e086a51bfa1 673 Pfam PF01935 Domain of unknown function DUF87 174 250 2.0E-8 T 23-10-2018 IPR002789 Helicase HerA, central domain APE_0080.1 d5077358872a80b86a519e086a51bfa1 673 Gene3D G3DSA:3.40.50.300 443 649 2.1E-18 T 23-10-2018 APE_0080.1 d5077358872a80b86a519e086a51bfa1 673 Gene3D G3DSA:3.40.50.300 163 293 1.4E-11 T 23-10-2018 APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 Pfam PF02779 Transketolase, pyrimidine binding domain 10 172 5.2E-33 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 SMART SM00861 10 176 1.9E-37 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 Gene3D G3DSA:3.40.50.920 187 321 2.7E-29 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 Pfam PF02780 Transketolase, C-terminal domain 189 311 2.4E-26 T 23-10-2018 IPR033248 Transketolase, C-terminal domain APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 Gene3D G3DSA:3.40.50.970 3 184 3.2E-46 T 23-10-2018 APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 SUPERFAMILY SSF52518 10 175 4.42E-43 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_0583 ef22660bb15ca09c2cf814e5e97d706b 322 SUPERFAMILY SSF52922 182 318 2.09E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_0152a d867589be72bee9501270027455e796d 88 SUPERFAMILY SSF46785 5 74 9.67E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0152a d867589be72bee9501270027455e796d 88 Gene3D G3DSA:1.10.10.10 1 86 7.9E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0085a e40b17aa6fb4904906c8d16abaf4aee5 148 SUPERFAMILY SSF52833 2 141 1.63E-5 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_2336.1 c2ad38041776d18bb9c305f00c08cf78 471 Gene3D G3DSA:2.40.380.10 308 471 7.3E-10 T 23-10-2018 IPR035930 FomD-like superfamily APE_2336.1 c2ad38041776d18bb9c305f00c08cf78 471 PIRSF PIRSF018644 1 468 5.5E-156 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 APE_2336.1 c2ad38041776d18bb9c305f00c08cf78 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 3 466 32.226 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 APE_2336.1 c2ad38041776d18bb9c305f00c08cf78 471 Pfam PF04167 Protein of unknown function (DUF402) 372 438 2.5E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 APE_2336.1 c2ad38041776d18bb9c305f00c08cf78 471 SUPERFAMILY SSF159234 312 466 8.11E-27 T 23-10-2018 IPR035930 FomD-like superfamily APE_0089.1 e660011e6fc822dd83fded09322ef061 482 Gene3D G3DSA:3.30.2290.10 16 211 1.8E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal APE_0089.1 e660011e6fc822dd83fded09322ef061 482 SUPERFAMILY SSF111283 19 482 2.49E-93 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 APE_0089.1 e660011e6fc822dd83fded09322ef061 482 PIRSF PIRSF004919 13 482 3.3E-167 T 23-10-2018 IPR025502 TldD APE_0089.1 e660011e6fc822dd83fded09322ef061 482 Pfam PF01523 Putative modulator of DNA gyrase 33 333 9.9E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 SUPERFAMILY SSF53706 61 1096 0.0 T 23-10-2018 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 Pfam PF00384 Molybdopterin oxidoreductase 140 863 6.6E-133 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 Pfam PF01568 Molydopterin dinucleotide binding domain 1130 1236 4.9E-19 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 Gene3D G3DSA:3.40.50.12440 76 1275 0.0 T 23-10-2018 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 SUPERFAMILY SSF50692 1130 1270 4.52E-39 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 80 98 - T 23-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 38 0.0015 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 61 1268 0.0 T 23-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 APE_1288.1 b688e85ca712f738d1b3d089cc7bc18d 1283 SMART SM00926 75 137 0.0056 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_2007 236cd9190f6426ef0e434bd398e38582 372 Pfam PF13167 GTP-binding GTPase N-terminal 17 99 2.5E-11 T 23-10-2018 IPR025121 GTPase HflX, N-terminal APE_2007 236cd9190f6426ef0e434bd398e38582 372 Gene3D G3DSA:3.40.50.300 183 362 8.1E-40 T 23-10-2018 APE_2007 236cd9190f6426ef0e434bd398e38582 372 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 253 271 2.1E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 207 225 2.1E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 186 206 2.1E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 17 355 1.6E-67 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 Pfam PF01926 50S ribosome-binding GTPase 185 306 3.8E-16 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 Hamap MF_00900 GTPase HflX [hflX]. 19 372 37.854 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 PIRSF PIRSF006809 1 367 2.7E-96 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 APE_2007 236cd9190f6426ef0e434bd398e38582 372 Pfam PF16360 GTP-binding GTPase Middle Region 101 178 4.9E-13 T 23-10-2018 IPR032305 GTP-binding protein, middle domain APE_2007 236cd9190f6426ef0e434bd398e38582 372 Gene3D G3DSA:3.40.50.11060 11 126 6.2E-21 T 23-10-2018 APE_2007 236cd9190f6426ef0e434bd398e38582 372 SUPERFAMILY SSF52540 185 357 1.75E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1084.1 f8f8207070c6d49547ec3504e6430755 151 Gene3D G3DSA:1.10.287.370 8 139 6.3E-13 T 23-10-2018 IPR009053 Prefoldin APE_1084.1 f8f8207070c6d49547ec3504e6430755 151 SUPERFAMILY SSF46579 9 136 3.66E-16 T 23-10-2018 APE_1084.1 f8f8207070c6d49547ec3504e6430755 151 Pfam PF02996 Prefoldin subunit 19 135 4.5E-23 T 23-10-2018 IPR004127 Prefoldin alpha-like APE_1084.1 f8f8207070c6d49547ec3504e6430755 151 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 1 137 12.416 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 SUPERFAMILY SSF50249 37 112 1.63E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 12 111 1.8E-46 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 PRINTS PR00973 Ribosomal protein S17 family signature 56 79 1.0E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 PRINTS PR00973 Ribosomal protein S17 family signature 99 106 1.0E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 PRINTS PR00973 Ribosomal protein S17 family signature 89 99 1.0E-9 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 Gene3D G3DSA:2.40.50.1000 4 114 1.2E-34 T 23-10-2018 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 8 113 31.145 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 56 108 5.0E-25 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0360.1 19ce752d59815c89bdb5599caa5405be 114 Pfam PF00366 Ribosomal protein S17 42 109 4.2E-23 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1692.1 6de400c30d0a6d42a35685a98863b042 176 Pfam PF00719 Inorganic pyrophosphatase 19 174 2.5E-54 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APE_1692.1 6de400c30d0a6d42a35685a98863b042 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APE_1692.1 6de400c30d0a6d42a35685a98863b042 176 Gene3D G3DSA:3.90.80.10 2 175 5.0E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APE_1692.1 6de400c30d0a6d42a35685a98863b042 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 174 38.005 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APE_1692.1 6de400c30d0a6d42a35685a98863b042 176 SUPERFAMILY SSF50324 7 174 3.53E-64 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 APE_1520.1 1059d5a754dda376704270f94e25013f 136 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 135 4.2E-34 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 APE_1520.1 1059d5a754dda376704270f94e25013f 136 SUPERFAMILY SSF111038 3 133 1.44E-38 T 23-10-2018 IPR035917 YjbQ-like superfamily APE_1520.1 1059d5a754dda376704270f94e25013f 136 Pfam PF01894 Uncharacterised protein family UPF0047 20 131 7.3E-33 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 APE_1520.1 1059d5a754dda376704270f94e25013f 136 Gene3D G3DSA:2.60.120.460 3 136 3.8E-48 T 23-10-2018 IPR035917 YjbQ-like superfamily APE_1520.1 1059d5a754dda376704270f94e25013f 136 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 98 116 - T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 APE_1520.1 1059d5a754dda376704270f94e25013f 136 PIRSF PIRSF004681 1 136 4.2E-33 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 APE_0409.1 61ace40f1e9f6d493e64aeed28613d71 200 Gene3D G3DSA:3.30.2320.30 85 198 2.1E-10 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0409.1 61ace40f1e9f6d493e64aeed28613d71 200 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 6 199 11.621 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0409.1 61ace40f1e9f6d493e64aeed28613d71 200 Pfam PF01991 ATP synthase (E/31 kDa) subunit 29 198 7.8E-7 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0409.1 61ace40f1e9f6d493e64aeed28613d71 200 SUPERFAMILY SSF160527 85 198 1.31E-10 T 23-10-2018 APE_2056.1 4e273d3729ed04e4901151a50400fbc5 151 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 APE_2056.1 4e273d3729ed04e4901151a50400fbc5 151 Pfam PF00293 NUDIX domain 10 120 2.2E-16 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APE_2056.1 4e273d3729ed04e4901151a50400fbc5 151 SUPERFAMILY SSF55811 3 128 3.38E-25 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APE_2056.1 4e273d3729ed04e4901151a50400fbc5 151 Gene3D G3DSA:3.90.79.10 3 138 3.4E-24 T 23-10-2018 APE_1415 99be49313b012129fff1bf7567bfb850 513 Pfam PF00361 Proton-conducting membrane transporter 142 423 5.2E-57 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1415 99be49313b012129fff1bf7567bfb850 513 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 395 421 1.1E-17 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1415 99be49313b012129fff1bf7567bfb850 513 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 1.1E-17 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1415 99be49313b012129fff1bf7567bfb850 513 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 1.1E-17 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1415 99be49313b012129fff1bf7567bfb850 513 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 178 202 1.1E-17 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1415 99be49313b012129fff1bf7567bfb850 513 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 147 166 1.1E-17 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1639 3b3c589808233a3647f765bbb89ca719 583 Gene3D G3DSA:3.30.930.10 13 457 1.3E-119 T 23-10-2018 APE_1639 3b3c589808233a3647f765bbb89ca719 583 Gene3D G3DSA:3.40.50.800 467 578 2.4E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily APE_1639 3b3c589808233a3647f765bbb89ca719 583 Pfam PF03129 Anticodon binding domain 475 565 3.5E-25 T 23-10-2018 IPR004154 Anticodon-binding APE_1639 3b3c589808233a3647f765bbb89ca719 583 Gene3D G3DSA:1.10.30.30 357 429 1.3E-119 T 23-10-2018 APE_1639 3b3c589808233a3647f765bbb89ca719 583 SUPERFAMILY SSF55681 5 478 5.18E-103 T 23-10-2018 APE_1639 3b3c589808233a3647f765bbb89ca719 583 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 565 4.9E-184 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 SUPERFAMILY SSF52954 462 576 2.42E-36 T 23-10-2018 APE_1639 3b3c589808233a3647f765bbb89ca719 583 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 4 569 56.382 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 APE_1639 3b3c589808233a3647f765bbb89ca719 583 Gene3D G3DSA:1.20.1430.20 85 148 1.3E-119 T 23-10-2018 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 143 155 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 514 533 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 194 211 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 211 221 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1639 3b3c589808233a3647f765bbb89ca719 583 PRINTS PR01043 Glycyl-tRNA synthetase signature 162 179 6.1E-50 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 Pfam PF02637 GatB domain 334 478 3.1E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 5 479 31.499 T 23-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 Pfam PF02934 GatB/GatE catalytic domain 8 294 3.1E-88 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 SUPERFAMILY SSF55931 6 299 2.16E-93 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 SMART SM00845 333 478 6.4E-31 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 Gene3D G3DSA:1.10.10.410 419 480 5.8E-18 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 7 478 1.5E-121 T 23-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 157 171 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 APE_1718 a4a4bb2ebb9bd1e55099e7c42c4b447f 486 SUPERFAMILY SSF89095 337 478 1.27E-7 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 APE_2087.1 a46b9d136556f674fe62b4d09fbc74ef 402 Pfam PF04412 Protein of unknown function (DUF521) 1 396 1.2E-125 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 Gene3D G3DSA:3.40.50.300 436 654 1.3E-36 T 23-10-2018 APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 Gene3D G3DSA:3.40.630.30 184 379 1.4E-8 T 23-10-2018 APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 SUPERFAMILY SSF52540 452 642 5.05E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 Pfam PF00005 ABC transporter 456 592 4.1E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 SUPERFAMILY SSF55729 127 364 9.75E-11 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 SMART SM00382 465 644 2.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2272.1 ddf0ad80bfdc3c5423bd1dee31bf2168 657 Pfam PF00583 Acetyltransferase (GNAT) family 293 358 7.1E-5 T 23-10-2018 IPR000182 GNAT domain APE_1300.1 9d72b389ab8902f68f6f02186ec49b08 178 Pfam PF02613 Nitrate reductase delta subunit 38 148 8.0E-11 T 23-10-2018 IPR020945 DMSO/Nitrate reductase chaperone APE_1300.1 9d72b389ab8902f68f6f02186ec49b08 178 Gene3D G3DSA:1.10.4070.10 66 154 2.5E-15 T 23-10-2018 APE_1300.1 9d72b389ab8902f68f6f02186ec49b08 178 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 9 165 3.8E-66 T 23-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 APE_1300.1 9d72b389ab8902f68f6f02186ec49b08 178 SUPERFAMILY SSF89155 2 169 5.76E-23 T 23-10-2018 IPR036411 TorD-like superfamily APE_1300.1 9d72b389ab8902f68f6f02186ec49b08 178 Gene3D G3DSA:1.20.120.700 5 168 2.5E-15 T 23-10-2018 APE_1471.1 d45a08ab31e10c67b126f6fbdbe67ad0 101 Gene3D G3DSA:3.30.1130.10 4 98 1.0E-15 T 23-10-2018 APE_1471.1 d45a08ab31e10c67b126f6fbdbe67ad0 101 SUPERFAMILY SSF55620 4 84 5.04E-17 T 23-10-2018 APE_1471.1 d45a08ab31e10c67b126f6fbdbe67ad0 101 Pfam PF14489 QueF-like protein 16 74 2.1E-10 T 23-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 1 896 21.883 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Gene3D G3DSA:3.30.930.10 1 235 1.5E-85 T 23-10-2018 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 SUPERFAMILY SSF101353 278 465 2.62E-42 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Gene3D G3DSA:2.40.30.130 480 575 6.4E-25 T 23-10-2018 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Pfam PF02272 DHHA1 domain 758 898 3.8E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 SUPERFAMILY SSF55186 579 727 1.83E-44 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Pfam PF01411 tRNA synthetases class II (A) 48 579 1.8E-114 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Gene3D G3DSA:3.30.54.20 647 702 2.0E-44 T 23-10-2018 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 PRINTS PR00980 Alanyl-tRNA synthetase signature 335 348 4.4E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 PRINTS PR00980 Alanyl-tRNA synthetase signature 114 125 4.4E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 PRINTS PR00980 Alanyl-tRNA synthetase signature 194 205 4.4E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 PRINTS PR00980 Alanyl-tRNA synthetase signature 220 233 4.4E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 PRINTS PR00980 Alanyl-tRNA synthetase signature 311 327 4.4E-16 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 SUPERFAMILY SSF50447 487 575 1.87E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 49 875 3.6E-191 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Gene3D G3DSA:3.10.310.40 789 897 1.4E-8 T 23-10-2018 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 678 721 4.4E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 SUPERFAMILY SSF55681 44 239 2.11E-55 T 23-10-2018 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 Gene3D G3DSA:3.30.980.10 579 720 2.0E-44 T 23-10-2018 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 1 894 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 APE_2166 1efd9d9fea95fa9b2b82f8cf4b28f2c3 900 SMART SM00863 678 721 3.6E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 SMART SM00487 18 224 1.3E-39 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 Gene3D G3DSA:3.40.50.300 1 210 1.1E-45 T 23-10-2018 APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 Pfam PF00270 DEAD/DEAH box helicase 24 194 3.2E-29 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 Gene3D G3DSA:3.40.50.300 233 377 8.7E-29 T 23-10-2018 APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 Pfam PF08494 DEAD/H associated 607 772 3.6E-14 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 SUPERFAMILY SSF52540 31 355 4.41E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 Pfam PF00271 Helicase conserved C-terminal domain 240 343 3.3E-18 T 23-10-2018 IPR001650 Helicase, C-terminal APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 PIRSF PIRSF037307 3 947 4.0E-298 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 APE_2188.1 1cc3fb155e5a55c775c58dd21c9fe716 948 SMART SM00490 264 347 1.3E-19 T 23-10-2018 IPR001650 Helicase, C-terminal APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 26 657 1.4E-266 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Pfam PF16661 Metallo-beta-lactamase superfamily domain 211 364 9.8E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Gene3D G3DSA:3.30.300.20 78 148 5.2E-53 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Gene3D G3DSA:3.30.300.230 19 181 5.2E-53 T 23-10-2018 APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 579 632 1.2E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Gene3D G3DSA:3.60.15.10 197 630 9.4E-147 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 SUPERFAMILY SSF56281 192 660 9.34E-123 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Pfam PF10996 Beta-Casp domain 437 561 2.1E-25 T 23-10-2018 IPR022712 Beta-Casp domain APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Pfam PF17214 KH domain 20 81 3.5E-18 T 23-10-2018 IPR033769 KH domain, archaeal APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 SMART SM01027 436 561 3.8E-54 T 23-10-2018 IPR022712 Beta-Casp domain APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 SMART SM00849 204 400 1.3E-22 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0522.1 b2d490d3359243b8e850cd044ce5a7b4 671 Gene3D G3DSA:3.40.50.10890 404 591 9.4E-147 T 23-10-2018 APE_0508.1 b3e6996ec3dc3625ab597c95f065e39f 183 SUPERFAMILY SSF57783 7 41 9.64E-9 T 23-10-2018 APE_0508.1 b3e6996ec3dc3625ab597c95f065e39f 183 Gene3D G3DSA:2.20.25.10 3 46 8.1E-10 T 23-10-2018 APE_0508.1 b3e6996ec3dc3625ab597c95f065e39f 183 Pfam PF08271 TFIIB zinc-binding 8 41 3.1E-8 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type APE_1452 993b0b8b1c52d20ee70823dc03abb2bd 225 ProSitePatterns PS01194 Ribosomal protein L15e signature. 48 71 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1452 993b0b8b1c52d20ee70823dc03abb2bd 225 SMART SM01384 4 189 3.7E-118 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1452 993b0b8b1c52d20ee70823dc03abb2bd 225 Gene3D G3DSA:3.40.1120.10 2 197 7.2E-80 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1452 993b0b8b1c52d20ee70823dc03abb2bd 225 Pfam PF00827 Ribosomal L15 4 192 3.9E-83 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1452 993b0b8b1c52d20ee70823dc03abb2bd 225 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 3 197 42.635 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1452 993b0b8b1c52d20ee70823dc03abb2bd 225 SUPERFAMILY SSF54189 3 195 6.23E-81 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 9 102 3.6E-11 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 Gene3D G3DSA:3.70.10.10 4 243 1.8E-69 T 23-10-2018 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 4 248 29.908 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 130 247 2.6E-5 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 SUPERFAMILY SSF55979 5 127 2.42E-28 T 23-10-2018 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 234 249 2.2E-6 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 36 54 2.2E-6 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 APE_0441.1 12c8f1462edfac93f4412b31314ef505 249 SUPERFAMILY SSF55979 126 248 1.72E-23 T 23-10-2018 APE_2034.1 cf5776fc1bb50b104e0b343e28cbb195 183 SUPERFAMILY SSF53448 3 163 4.06E-27 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_2034.1 cf5776fc1bb50b104e0b343e28cbb195 183 Pfam PF12804 MobA-like NTP transferase domain 4 130 1.6E-20 T 23-10-2018 IPR025877 MobA-like NTP transferase APE_2034.1 cf5776fc1bb50b104e0b343e28cbb195 183 Gene3D G3DSA:3.90.550.10 2 171 2.1E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_2136.1 6512cfa3f370c81a67d5fd4acc40bf7f 326 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 3 323 5.6E-119 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family APE_2136.1 6512cfa3f370c81a67d5fd4acc40bf7f 326 Gene3D G3DSA:3.40.190.10 37 323 2.6E-99 T 23-10-2018 APE_2136.1 6512cfa3f370c81a67d5fd4acc40bf7f 326 Gene3D G3DSA:3.40.190.10 123 261 2.6E-99 T 23-10-2018 APE_2136.1 6512cfa3f370c81a67d5fd4acc40bf7f 326 Pfam PF16868 NMT1-like family 37 323 2.5E-82 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family APE_2136.1 6512cfa3f370c81a67d5fd4acc40bf7f 326 SUPERFAMILY SSF53850 34 325 4.78E-73 T 23-10-2018 APE_0562a 44cafd11322ce2581b292bf9e14ad76a 83 SMART SM00830 7 77 1.9E-15 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APE_0562a 44cafd11322ce2581b292bf9e14ad76a 83 SUPERFAMILY SSF48600 3 75 1.14E-15 T 23-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APE_0562a 44cafd11322ce2581b292bf9e14ad76a 83 Gene3D G3DSA:1.20.59.10 2 76 3.3E-14 T 23-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APE_0562a 44cafd11322ce2581b292bf9e14ad76a 83 Pfam PF01817 Chorismate mutase type II 7 74 1.5E-14 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 APE_2080.1 f59e727ab354fb36b4c1080f2e2a7c7e 156 Pfam PF00293 NUDIX domain 11 128 6.8E-22 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APE_2080.1 f59e727ab354fb36b4c1080f2e2a7c7e 156 Gene3D G3DSA:3.90.79.10 5 140 1.3E-35 T 23-10-2018 APE_2080.1 f59e727ab354fb36b4c1080f2e2a7c7e 156 PRINTS PR00502 NUDIX hydrolase family signature 37 51 5.6E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APE_2080.1 f59e727ab354fb36b4c1080f2e2a7c7e 156 PRINTS PR00502 NUDIX hydrolase family signature 51 66 5.6E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APE_2080.1 f59e727ab354fb36b4c1080f2e2a7c7e 156 SUPERFAMILY SSF55811 6 139 2.84E-35 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APE_2080.1 f59e727ab354fb36b4c1080f2e2a7c7e 156 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 APE_1754.1 59cc21d797d28a45675f12be77dedf9e 391 Gene3D G3DSA:3.40.640.10 31 302 8.5E-78 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1754.1 59cc21d797d28a45675f12be77dedf9e 391 Gene3D G3DSA:3.90.1150.10 17 383 8.5E-78 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_1754.1 59cc21d797d28a45675f12be77dedf9e 391 Pfam PF00266 Aminotransferase class-V 20 382 2.3E-35 T 23-10-2018 IPR000192 Aminotransferase class V domain APE_1754.1 59cc21d797d28a45675f12be77dedf9e 391 SUPERFAMILY SSF53383 7 389 3.82E-74 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_1828.1 5e37988a7eb2383ba2ab7450ed903970 281 Pfam PF01061 ABC-2 type transporter 29 230 1.4E-10 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APE_0682.1 97ff7c18e911c765bdbaef4070064b7e 173 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 163 2.3E-28 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 APE_0682.1 97ff7c18e911c765bdbaef4070064b7e 173 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 166 3.3E-24 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 APE_0682.1 97ff7c18e911c765bdbaef4070064b7e 173 SUPERFAMILY SSF56300 2 167 1.49E-28 T 23-10-2018 APE_0682.1 97ff7c18e911c765bdbaef4070064b7e 173 Gene3D G3DSA:3.60.21.10 1 171 6.3E-38 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_2519.1 0a42fd5c2731a79b616c5f6270334118 248 SUPERFAMILY SSF54593 150 220 3.99E-15 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_2519.1 0a42fd5c2731a79b616c5f6270334118 248 Gene3D G3DSA:3.10.180.10 150 232 1.5E-13 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_2519.1 0a42fd5c2731a79b616c5f6270334118 248 SUPERFAMILY SSF54593 10 122 1.48E-25 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_2519.1 0a42fd5c2731a79b616c5f6270334118 248 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 118 2.9E-5 T 23-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APE_2519.1 0a42fd5c2731a79b616c5f6270334118 248 Gene3D G3DSA:3.10.180.10 7 140 3.4E-17 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 Gene3D G3DSA:3.40.50.1370 134 293 3.8E-100 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 4.8E-21 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 4.8E-21 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 270 4.8E-21 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 294 4.8E-21 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 304 1.7E-21 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 9 306 2.9E-121 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 8 308 35.96 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 146 3.9E-42 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 133 150 1.5E-33 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 1.5E-33 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 287 301 1.5E-33 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 40 62 1.5E-33 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 1.5E-33 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 265 270 1.5E-33 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 SUPERFAMILY SSF53671 5 307 5.37E-91 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APE_1663.1 d1a25bb86608a52ecd27ea0183112904 308 Gene3D G3DSA:3.40.50.1370 11 302 3.8E-100 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APE_1382 b7084fbd9524010c63e3068726196681 450 Gene3D G3DSA:1.10.4160.10 4 372 3.5E-46 T 23-10-2018 IPR038271 Purine-cytosine permease superfamily APE_1382 b7084fbd9524010c63e3068726196681 450 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 15 369 8.4E-21 T 23-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 271 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 PIRSF PIRSF000521 354 416 110.0 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 PIRSF PIRSF000521 33 127 0.58 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 PIRSF PIRSF000521 180 372 4.7E-10 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 Pfam PF00202 Aminotransferase class-III 31 396 1.9E-68 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 SUPERFAMILY SSF53383 4 424 4.46E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2299.1 a2d33c8319b08291be34564490e385ad 429 Gene3D G3DSA:3.90.1150.10 9 407 4.6E-167 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 426 91.86 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 Gene3D G3DSA:3.40.640.10 70 319 4.6E-167 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2299.1 a2d33c8319b08291be34564490e385ad 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 425 1.6E-187 T 23-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 APE_2260 2814425e3b0bf9ea8e9c047b57b6e7f0 280 Gene3D G3DSA:1.10.3720.10 66 279 8.2E-20 T 23-10-2018 IPR035906 MetI-like superfamily APE_2260 2814425e3b0bf9ea8e9c047b57b6e7f0 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 276 3.2E-26 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_2260 2814425e3b0bf9ea8e9c047b57b6e7f0 280 SUPERFAMILY SSF161098 74 261 3.27E-24 T 23-10-2018 IPR035906 MetI-like superfamily APE_2260 2814425e3b0bf9ea8e9c047b57b6e7f0 280 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 49 4.8E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 449 20.675 T 23-10-2018 IPR026593 Protein translocase subunit SecY APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 SUPERFAMILY SSF103491 6 439 2.35E-103 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 6.7E-6 T 23-10-2018 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 PRINTS PR00303 Preprotein translocase SecY subunit signature 418 436 6.7E-6 T 23-10-2018 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 PRINTS PR00303 Preprotein translocase SecY subunit signature 335 357 6.7E-6 T 23-10-2018 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 6.7E-6 T 23-10-2018 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 Pfam PF10559 Plug domain of Sec61p 38 72 7.1E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 28 440 1.2E-76 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 PIRSF PIRSF004557 4 457 2.8E-123 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 Gene3D G3DSA:1.10.3370.10 4 454 6.8E-142 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0983.1 d6e6f5d61b992a1019e6a2556e9a4e82 457 Pfam PF00344 SecY translocase 73 433 6.0E-63 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_2580 737feae0b5501299f79e626523b00b90 263 SMART SM00903 11 155 3.3E-24 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APE_2580 737feae0b5501299f79e626523b00b90 263 SUPERFAMILY SSF50475 7 168 3.93E-35 T 23-10-2018 APE_2580 737feae0b5501299f79e626523b00b90 263 Gene3D G3DSA:2.30.110.10 6 178 2.7E-40 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 APE_2580 737feae0b5501299f79e626523b00b90 263 Pfam PF01613 Flavin reductase like domain 19 167 1.0E-18 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 APE_0572 5a07fd89788c75f48644902deb1e97af 280 Pfam PF00288 GHMP kinases N terminal domain 80 144 4.0E-6 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 APE_0572 5a07fd89788c75f48644902deb1e97af 280 Hamap MF_00370 Shikimate kinase [aroK]. 1 280 46.455 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 APE_0572 5a07fd89788c75f48644902deb1e97af 280 SUPERFAMILY SSF54211 13 157 1.75E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_0572 5a07fd89788c75f48644902deb1e97af 280 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 6 273 7.0E-92 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 APE_0572 5a07fd89788c75f48644902deb1e97af 280 PIRSF PIRSF005758 1 280 2.1E-84 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 APE_0572 5a07fd89788c75f48644902deb1e97af 280 Pfam PF08544 GHMP kinases C terminal 218 265 1.3E-5 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain APE_0572 5a07fd89788c75f48644902deb1e97af 280 Gene3D G3DSA:3.30.230.10 32 158 1.1E-8 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_0514 fa671ad0a887040845b09298873b3e5e 352 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 51 139 9.5E-14 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 APE_0514 fa671ad0a887040845b09298873b3e5e 352 Gene3D G3DSA:3.40.50.150 139 352 3.7E-59 T 23-10-2018 APE_0514 fa671ad0a887040845b09298873b3e5e 352 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 234 1.4E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_0514 fa671ad0a887040845b09298873b3e5e 352 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 125 139 1.4E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_0514 fa671ad0a887040845b09298873b3e5e 352 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 154 164 1.4E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_0514 fa671ad0a887040845b09298873b3e5e 352 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 272 288 1.4E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_0514 fa671ad0a887040845b09298873b3e5e 352 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 333 350 1.4E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_0514 fa671ad0a887040845b09298873b3e5e 352 Gene3D G3DSA:3.30.70.3130 31 138 3.8E-29 T 23-10-2018 APE_0514 fa671ad0a887040845b09298873b3e5e 352 Pfam PF01189 16S rRNA methyltransferase RsmB/F 143 347 3.4E-47 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 APE_0514 fa671ad0a887040845b09298873b3e5e 352 SUPERFAMILY SSF53335 44 350 8.95E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1838.1 1cdedde9ad1513e190b4364d6119aae0 135 Pfam PF00571 CBS domain 70 125 5.6E-16 T 23-10-2018 IPR000644 CBS domain APE_1838.1 1cdedde9ad1513e190b4364d6119aae0 135 Pfam PF00571 CBS domain 13 60 2.9E-10 T 23-10-2018 IPR000644 CBS domain APE_1838.1 1cdedde9ad1513e190b4364d6119aae0 135 Gene3D G3DSA:3.10.580.10 10 132 2.9E-39 T 23-10-2018 APE_1838.1 1cdedde9ad1513e190b4364d6119aae0 135 SMART SM00116 13 61 1.6E-9 T 23-10-2018 IPR000644 CBS domain APE_1838.1 1cdedde9ad1513e190b4364d6119aae0 135 SMART SM00116 77 125 8.2E-14 T 23-10-2018 IPR000644 CBS domain APE_1838.1 1cdedde9ad1513e190b4364d6119aae0 135 SUPERFAMILY SSF54631 13 124 1.89E-35 T 23-10-2018 APE_2496.1 8ab8f0d7749f1428231d72d9ad281c1d 143 ProSitePatterns PS00194 Thioredoxin family active site. 54 72 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 APE_2496.1 8ab8f0d7749f1428231d72d9ad281c1d 143 Pfam PF00085 Thioredoxin 45 134 5.0E-14 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 APE_2496.1 8ab8f0d7749f1428231d72d9ad281c1d 143 Gene3D G3DSA:3.40.30.10 36 139 2.2E-21 T 23-10-2018 APE_2496.1 8ab8f0d7749f1428231d72d9ad281c1d 143 SUPERFAMILY SSF52833 4 138 4.96E-28 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 SUPERFAMILY SSF52540 6 246 3.59E-82 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 SUPERFAMILY SSF50331 248 336 6.23E-12 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 Pfam PF08402 TOBE domain 261 336 1.1E-11 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 Pfam PF00005 ABC transporter 21 166 5.1E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 Gene3D G3DSA:3.40.50.300 3 243 1.5E-81 T 23-10-2018 APE_0944.1 b2bdc227a3ad6747e7f842feea44cda6 342 SMART SM00382 30 224 4.5E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 Gene3D G3DSA:1.10.439.10 44 203 2.5E-40 T 23-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 PIRSF PIRSF001227 20 850 1.0E-237 T 23-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 Pfam PF01804 Penicillin amidase 63 833 1.1E-153 T 23-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 Gene3D G3DSA:3.60.20.10 305 829 1.7E-103 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 Gene3D G3DSA:2.30.120.10 377 445 1.7E-103 T 23-10-2018 APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 SUPERFAMILY SSF56235 61 837 1.18E-165 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_0336.1 c733b888cee3b9c456f4c3ff915abab6 851 Gene3D G3DSA:1.10.1400.10 609 743 1.7E-103 T 23-10-2018 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 Gene3D G3DSA:1.10.275.10 1 111 2.1E-36 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 2.0E-25 T 23-10-2018 IPR000362 Fumarate lyase family APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 2.0E-25 T 23-10-2018 IPR000362 Fumarate lyase family APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00149 Fumarate lyase superfamily signature 244 271 2.0E-25 T 23-10-2018 IPR000362 Fumarate lyase family APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00149 Fumarate lyase superfamily signature 107 125 2.0E-25 T 23-10-2018 IPR000362 Fumarate lyase family APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 1.8E-7 T 23-10-2018 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00145 Argininosuccinate lyase family signature 106 128 1.8E-7 T 23-10-2018 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 1.8E-7 T 23-10-2018 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 Pfam PF10415 Fumarase C C-terminus 381 431 1.7E-8 T 23-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 SUPERFAMILY SSF48557 2 430 2.5E-110 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 Gene3D G3DSA:1.20.200.10 112 380 1.2E-75 T 23-10-2018 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 Pfam PF00206 Lyase 14 311 7.0E-86 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 Gene3D G3DSA:1.10.40.30 381 437 1.7E-8 T 23-10-2018 APE_1816.1 9309d14eb93a9ed519ff8d84755add25 444 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 Gene3D G3DSA:3.40.50.720 2 250 3.0E-85 T 23-10-2018 APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.4E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.4E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.4E-11 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 5.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.3E-40 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 0.0032 T 23-10-2018 APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 1.0E-60 T 23-10-2018 APE_2503.1 98d721a2593e318e16a347cc386a4bb1 250 SUPERFAMILY SSF51735 5 248 9.16E-77 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_2382.1 6bea683a6021fd56ef743a756eb1c8d2 385 PIRSF PIRSF000429 142 366 1.6E-11 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_2382.1 6bea683a6021fd56ef743a756eb1c8d2 385 PIRSF PIRSF000429 3 55 120.0 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_2382.1 6bea683a6021fd56ef743a756eb1c8d2 385 Gene3D G3DSA:3.40.47.10 2 384 9.2E-64 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2382.1 6bea683a6021fd56ef743a756eb1c8d2 385 SUPERFAMILY SSF53901 230 357 2.3E-11 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2382.1 6bea683a6021fd56ef743a756eb1c8d2 385 SUPERFAMILY SSF53901 3 225 3.02E-15 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 ProSitePatterns PS00018 EF-hand calcium-binding domain. 340 352 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 Gene3D G3DSA:3.10.105.10 567 740 1.3E-39 T 23-10-2018 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 Gene3D G3DSA:3.90.76.10 238 429 1.8E-22 T 23-10-2018 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 SUPERFAMILY SSF53850 132 211 2.35E-8 T 23-10-2018 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 SUPERFAMILY SSF53850 228 727 5.43E-79 T 23-10-2018 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 273 726 5.3E-63 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 Gene3D G3DSA:3.10.105.10 130 187 3.5E-8 T 23-10-2018 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 Gene3D G3DSA:3.40.190.10 440 561 2.0E-12 T 23-10-2018 APE_1390.1 551dbd058da0158608ed5f5c30eb147d 748 Gene3D G3DSA:3.40.190.10 188 199 3.5E-8 T 23-10-2018 APE_0060.1 e4ce37a5d8bb8f21b48006bc0bc61ba4 233 SUPERFAMILY SSF47413 9 63 9.48E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APE_0060.1 e4ce37a5d8bb8f21b48006bc0bc61ba4 233 SUPERFAMILY SSF53271 88 217 6.11E-18 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_0060.1 e4ce37a5d8bb8f21b48006bc0bc61ba4 233 Gene3D G3DSA:3.40.50.2020 74 229 5.5E-24 T 23-10-2018 APE_0060.1 e4ce37a5d8bb8f21b48006bc0bc61ba4 233 Gene3D G3DSA:1.10.260.40 2 73 1.7E-5 T 23-10-2018 APE_0060.1 e4ce37a5d8bb8f21b48006bc0bc61ba4 233 Pfam PF00156 Phosphoribosyl transferase domain 107 217 3.2E-8 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APE_0060.1 e4ce37a5d8bb8f21b48006bc0bc61ba4 233 SMART SM00530 13 69 3.2E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_2151.1 ee84e16046a86825aefbf9b61555814b 503 Gene3D G3DSA:3.90.226.10 84 299 2.4E-41 T 23-10-2018 APE_2151.1 ee84e16046a86825aefbf9b61555814b 503 SUPERFAMILY SSF141322 432 491 1.83E-12 T 23-10-2018 APE_2151.1 ee84e16046a86825aefbf9b61555814b 503 Gene3D G3DSA:2.40.50.140 424 502 8.8E-14 T 23-10-2018 APE_2151.1 ee84e16046a86825aefbf9b61555814b 503 SUPERFAMILY SSF52096 87 249 3.11E-24 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APE_2151.1 ee84e16046a86825aefbf9b61555814b 503 Pfam PF01957 NfeD-like C-terminal, partner-binding 348 491 1.8E-32 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 SUPERFAMILY SSF50331 241 367 2.33E-21 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 Gene3D G3DSA:2.40.50.100 243 365 9.0E-23 T 23-10-2018 APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 Gene3D G3DSA:2.40.50.140 289 352 9.0E-23 T 23-10-2018 APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 Gene3D G3DSA:3.40.50.300 1 242 3.7E-80 T 23-10-2018 APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 SUPERFAMILY SSF52540 4 247 4.17E-90 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 Pfam PF03459 TOBE domain 299 358 2.4E-13 T 23-10-2018 IPR005116 Transport-associated OB, type 1 APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 Pfam PF00005 ABC transporter 20 165 4.2E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0043.1 2471d79a1738aa5c0ccd867a893b01cd 368 SMART SM00382 28 215 8.0E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0152.1 0ac08b76f069ba946adad75045381a00 410 SUPERFAMILY SSF46785 299 405 2.18E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0152.1 0ac08b76f069ba946adad75045381a00 410 SUPERFAMILY SSF52540 7 289 4.02E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0152.1 0ac08b76f069ba946adad75045381a00 410 Gene3D G3DSA:1.10.10.10 298 410 3.6E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0152.1 0ac08b76f069ba946adad75045381a00 410 Gene3D G3DSA:1.10.8.60 217 287 5.2E-85 T 23-10-2018 APE_0152.1 0ac08b76f069ba946adad75045381a00 410 Pfam PF09079 CDC6, C terminal winged helix domain 315 385 2.0E-7 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 APE_0152.1 0ac08b76f069ba946adad75045381a00 410 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 6 384 1.9E-54 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea APE_0152.1 0ac08b76f069ba946adad75045381a00 410 Gene3D G3DSA:3.40.50.300 46 216 5.2E-85 T 23-10-2018 APE_0152.1 0ac08b76f069ba946adad75045381a00 410 Pfam PF13401 AAA domain 56 171 2.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0152.1 0ac08b76f069ba946adad75045381a00 410 SMART SM01074 311 397 9.4E-19 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 Gene3D G3DSA:4.10.950.10 160 238 4.4E-38 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 90 214 3.2E-44 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 Gene3D G3DSA:2.30.30.30 82 158 3.4E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 PIRSF PIRSF002158 1 238 7.2E-72 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 81 9.3E-17 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 ProSitePatterns PS00467 Ribosomal protein L2 signature. 187 198 - T 23-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 SUPERFAMILY SSF50104 91 235 4.75E-51 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily APE_0218 ebd528825ef055449b5c1aaf9413d420 238 SMART SM01382 88 221 8.7E-70 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 SUPERFAMILY SSF50249 2 87 5.48E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0218 ebd528825ef055449b5c1aaf9413d420 238 Gene3D G3DSA:2.40.50.140 1 78 1.3E-23 T 23-10-2018 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 236 41.804 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0218 ebd528825ef055449b5c1aaf9413d420 238 SMART SM01383 11 82 3.4E-25 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1428.1 69ffffb94a88ef087f229f29545f450b 199 SUPERFAMILY SSF56770 31 173 4.32E-52 T 23-10-2018 APE_1428.1 69ffffb94a88ef087f229f29545f450b 199 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 31 166 3.8E-48 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1428.1 69ffffb94a88ef087f229f29545f450b 199 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 79 160 4.2E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1428.1 69ffffb94a88ef087f229f29545f450b 199 Gene3D G3DSA:3.40.50.12280 11 178 1.9E-53 T 23-10-2018 APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 Gene3D G3DSA:3.90.650.10 150 338 1.4E-35 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 PIRSF PIRSF005644 9 338 1.4E-66 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 Gene3D G3DSA:3.30.1330.10 2 146 1.5E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 41 144 3.3E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 157 311 1.3E-20 T 23-10-2018 IPR010918 PurM-like, C-terminal domain APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 SUPERFAMILY SSF56042 154 312 6.15E-30 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APE_2044.1 3ce9e7017e5405b244e375ca33d4368c 345 SUPERFAMILY SSF55326 28 144 3.31E-22 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APE_1657.1 02e65bdb8ecc9039604250a7dd47592b 199 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 189 2.0E-38 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal APE_1657.1 02e65bdb8ecc9039604250a7dd47592b 199 Gene3D G3DSA:3.40.225.10 10 198 5.0E-48 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APE_1657.1 02e65bdb8ecc9039604250a7dd47592b 199 SMART SM01007 15 190 5.9E-47 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal APE_1657.1 02e65bdb8ecc9039604250a7dd47592b 199 SUPERFAMILY SSF53639 10 197 2.35E-46 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 SUPERFAMILY SSF51735 2 139 2.07E-43 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 PIRSF PIRSF000102 1 305 6.0E-103 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 Gene3D G3DSA:3.90.110.10 142 301 4.2E-57 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 139 8.0E-39 T 23-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 PRINTS PR00086 L-lactate dehydrogenase signature 113 133 1.8E-28 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 PRINTS PR00086 L-lactate dehydrogenase signature 25 49 1.8E-28 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 1.8E-28 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 PRINTS PR00086 L-lactate dehydrogenase signature 1 25 1.8E-28 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 PRINTS PR00086 L-lactate dehydrogenase signature 137 155 1.8E-28 T 23-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 SUPERFAMILY SSF56327 142 302 3.75E-46 T 23-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 144 300 2.1E-21 T 23-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 APE_0672.1 564a71b0b572a466ded5f7c4b9e01503 308 Gene3D G3DSA:3.40.50.720 1 141 4.1E-55 T 23-10-2018 APE_2133 f848cf3ba2c5c3d6b13c425a515b3855 731 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 72 722 1.5E-152 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ APE_2133 f848cf3ba2c5c3d6b13c425a515b3855 731 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 151 425 2.7E-53 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit APE_2133 f848cf3ba2c5c3d6b13c425a515b3855 731 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 455 650 1.6E-23 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit APE_1481.1 850bb3c4329b6a3ee91b14ec4f3e5f66 180 SUPERFAMILY SSF55811 6 168 8.53E-38 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APE_1481.1 850bb3c4329b6a3ee91b14ec4f3e5f66 180 Pfam PF00293 NUDIX domain 33 146 2.2E-19 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APE_1481.1 850bb3c4329b6a3ee91b14ec4f3e5f66 180 Gene3D G3DSA:3.90.79.10 2 175 6.1E-44 T 23-10-2018 APE_1481.1 850bb3c4329b6a3ee91b14ec4f3e5f66 180 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 APE_1481.1 850bb3c4329b6a3ee91b14ec4f3e5f66 180 PRINTS PR00502 NUDIX hydrolase family signature 79 94 1.2E-5 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APE_1481.1 850bb3c4329b6a3ee91b14ec4f3e5f66 180 PRINTS PR00502 NUDIX hydrolase family signature 65 79 1.2E-5 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 APE_0319 14aac536cee382922ec45ee85defe73f 180 Pfam PF01965 DJ-1/PfpI family 3 164 2.8E-59 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 APE_0319 14aac536cee382922ec45ee85defe73f 180 Gene3D G3DSA:3.40.50.880 1 171 3.7E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_0319 14aac536cee382922ec45ee85defe73f 180 SUPERFAMILY SSF52317 1 166 2.08E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_0319 14aac536cee382922ec45ee85defe73f 180 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 167 6.4E-58 T 23-10-2018 IPR006286 Deglycase PfpI APE_1836.1 02ba02476530991cd4f8356d3b5eaf0c 310 SUPERFAMILY SSF56281 6 308 7.47E-62 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1836.1 02ba02476530991cd4f8356d3b5eaf0c 310 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 5 308 8.3E-91 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 APE_1836.1 02ba02476530991cd4f8356d3b5eaf0c 310 Hamap MF_01818 Ribonuclease BN [rbn]. 4 308 30.505 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 APE_1836.1 02ba02476530991cd4f8356d3b5eaf0c 310 Pfam PF12706 Beta-lactamase superfamily domain 34 273 4.0E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_1836.1 02ba02476530991cd4f8356d3b5eaf0c 310 Gene3D G3DSA:3.60.15.10 4 308 6.7E-67 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1749 544cecd998487b288104090c55e4bf6a 157 ProSitePatterns PS00360 Ribosomal protein S9 signature. 77 95 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 APE_1749 544cecd998487b288104090c55e4bf6a 157 Gene3D G3DSA:3.30.230.10 7 157 2.7E-44 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_1749 544cecd998487b288104090c55e4bf6a 157 SUPERFAMILY SSF54211 12 157 3.41E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_1749 544cecd998487b288104090c55e4bf6a 157 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 12 157 2.1E-50 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1749 544cecd998487b288104090c55e4bf6a 157 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 12 157 36.091 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1749 544cecd998487b288104090c55e4bf6a 157 Pfam PF00380 Ribosomal protein S9/S16 17 157 1.2E-31 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 APE_1873.1 760f698481ab153c1e4feea3861faf7a 361 SUPERFAMILY SSF53901 183 356 1.84E-46 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1873.1 760f698481ab153c1e4feea3861faf7a 361 Hamap MF_01409 UPF0219 protein . 14 358 61.59 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related APE_1873.1 760f698481ab153c1e4feea3861faf7a 361 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 232 311 2.1E-10 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 APE_1873.1 760f698481ab153c1e4feea3861faf7a 361 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 15 357 1.3E-150 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related APE_1873.1 760f698481ab153c1e4feea3861faf7a 361 SUPERFAMILY SSF53901 15 178 1.05E-31 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1873.1 760f698481ab153c1e4feea3861faf7a 361 Gene3D G3DSA:3.40.47.10 13 356 4.7E-71 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 24 371 41.101 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 SUPERFAMILY SSF53137 141 274 1.09E-36 T 23-10-2018 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 Gene3D G3DSA:3.30.1330.30 276 373 2.8E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1988.1 7d986325be4a6bab368ee893120239a6 373 SUPERFAMILY SSF55315 281 371 1.06E-23 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1988.1 7d986325be4a6bab368ee893120239a6 373 Gene3D G3DSA:3.30.960.10 1 139 1.5E-49 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 Gene3D G3DSA:3.30.420.60 140 275 4.5E-48 T 23-10-2018 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 14 324 3.7E-127 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 Pfam PF03465 eRF1 domain 3 282 370 2.3E-23 T 23-10-2018 IPR005142 eRF1 domain 3 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 Pfam PF03464 eRF1 domain 2 143 274 7.5E-45 T 23-10-2018 IPR005141 eRF1 domain 2 APE_1988.1 7d986325be4a6bab368ee893120239a6 373 SMART SM01194 8 138 1.6E-32 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like APE_1988.1 7d986325be4a6bab368ee893120239a6 373 SUPERFAMILY SSF55481 7 139 6.02E-42 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2316 472e50d92707166667cb9c71d4533ea6 449 PIRSF PIRSF001413 11 438 1.7E-143 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2316 472e50d92707166667cb9c71d4533ea6 449 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 15 434 3.1E-211 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2316 472e50d92707166667cb9c71d4533ea6 449 Gene3D G3DSA:3.40.50.1100 15 425 8.7E-174 T 23-10-2018 APE_2316 472e50d92707166667cb9c71d4533ea6 449 Gene3D G3DSA:3.40.50.1100 16 243 8.7E-174 T 23-10-2018 APE_2316 472e50d92707166667cb9c71d4533ea6 449 SUPERFAMILY SSF53686 31 431 8.51E-112 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_2316 472e50d92707166667cb9c71d4533ea6 449 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 109 123 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2316 472e50d92707166667cb9c71d4533ea6 449 PIRSF PIRSF500824 3 441 1.0E-208 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2316 472e50d92707166667cb9c71d4533ea6 449 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 78 413 2.7E-42 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_2316 472e50d92707166667cb9c71d4533ea6 449 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 23 432 42.541 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_1011.1 79d61c40f5368690793721254ed1a89b 260 SUPERFAMILY SSF53335 34 236 2.94E-52 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1011.1 79d61c40f5368690793721254ed1a89b 260 Gene3D G3DSA:3.40.50.150 24 255 7.3E-88 T 23-10-2018 APE_1011.1 79d61c40f5368690793721254ed1a89b 260 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 40 244 1.9E-66 T 23-10-2018 APE_1011.1 79d61c40f5368690793721254ed1a89b 260 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 167 182 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 APE_1011.1 79d61c40f5368690793721254ed1a89b 260 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 40 245 4.6E-63 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 APE_1011.1 79d61c40f5368690793721254ed1a89b 260 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 32 247 42.086 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 APE_2592.1 768e0fb24cedf72289402bf26563ea5d 447 Gene3D G3DSA:3.40.50.2300 83 352 8.9E-73 T 23-10-2018 APE_2592.1 768e0fb24cedf72289402bf26563ea5d 447 SUPERFAMILY SSF53822 97 316 7.06E-7 T 23-10-2018 IPR028082 Periplasmic binding protein-like I APE_2592.1 768e0fb24cedf72289402bf26563ea5d 447 Gene3D G3DSA:3.40.50.2300 183 362 8.9E-73 T 23-10-2018 APE_2592.1 768e0fb24cedf72289402bf26563ea5d 447 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 78 369 3.4E-50 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 SMART SM00382 39 167 9.6E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 Hamap MF_01509 Replication factor C small subunit [rfcS]. 5 320 50.37 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 43 159 7.1E-16 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 Gene3D G3DSA:3.40.50.300 2 163 2.9E-57 T 23-10-2018 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 Pfam PF08542 Replication factor C C-terminal domain 228 314 1.2E-22 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 Gene3D G3DSA:1.10.8.60 165 225 4.0E-23 T 23-10-2018 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 SUPERFAMILY SSF48019 228 319 3.02E-21 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 SUPERFAMILY SSF52540 6 213 3.13E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1522.1 1cb410ef4c12090401419f333ad1cf3f 325 Gene3D G3DSA:1.20.272.10 227 322 1.5E-30 T 23-10-2018 APE_1559.1 aba5fc9f6a8448227a9041156e5edd5b 308 Pfam PF00753 Metallo-beta-lactamase superfamily 16 145 7.5E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_1559.1 aba5fc9f6a8448227a9041156e5edd5b 308 Gene3D G3DSA:3.60.15.10 3 220 3.1E-21 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1559.1 aba5fc9f6a8448227a9041156e5edd5b 308 SMART SM00849 17 196 9.6E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_1559.1 aba5fc9f6a8448227a9041156e5edd5b 308 SUPERFAMILY SSF56281 10 244 4.06E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 SUPERFAMILY SSF116846 10 73 5.89E-8 T 23-10-2018 IPR036181 MIT domain superfamily APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 Gene3D G3DSA:1.10.8.60 283 362 1.2E-92 T 23-10-2018 APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 Gene3D G3DSA:3.40.50.300 108 378 1.2E-92 T 23-10-2018 APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 148 282 9.8E-39 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 SMART SM00382 144 284 1.4E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 Pfam PF09336 Vps4 C terminal oligomerisation domain 346 381 9.9E-8 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 Gene3D G3DSA:1.20.58.280 2 81 5.9E-13 T 23-10-2018 APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 SMART SM00745 4 79 1.2E-15 T 23-10-2018 IPR007330 MIT APE_0960 7ea7556ad61fef71bc260ebcf506cd00 384 SUPERFAMILY SSF52540 109 380 4.71E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0680.1 8d037272c792a0980bb3953d203fe288 148 SUPERFAMILY SSF54637 3 136 2.67E-29 T 23-10-2018 IPR029069 HotDog domain superfamily APE_0680.1 8d037272c792a0980bb3953d203fe288 148 Pfam PF03061 Thioesterase superfamily 22 103 3.7E-4 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 APE_0680.1 8d037272c792a0980bb3953d203fe288 148 Gene3D G3DSA:3.10.129.10 2 138 7.0E-27 T 23-10-2018 APE_2512 f3a802c44e0492880444d0194ff2dc3a 268 Pfam PF01061 ABC-2 type transporter 8 221 1.1E-15 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APE_2512 f3a802c44e0492880444d0194ff2dc3a 268 PIRSF PIRSF006648 3 256 5.3E-19 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2512 f3a802c44e0492880444d0194ff2dc3a 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 6.7E-7 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2512 f3a802c44e0492880444d0194ff2dc3a 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 6.7E-7 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2512 f3a802c44e0492880444d0194ff2dc3a 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 58 80 6.7E-7 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_1968 67a8bb1c99734fc16b46f46813511518 316 Gene3D G3DSA:3.40.1160.10 1 316 4.1E-112 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 270 285 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 215 230 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 46 65 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 5.0E-51 T 23-10-2018 APE_1968 67a8bb1c99734fc16b46f46813511518 316 Pfam PF00696 Amino acid kinase family 6 296 5.3E-27 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APE_1968 67a8bb1c99734fc16b46f46813511518 316 PIRSF PIRSF000723 3 315 2.8E-125 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 APE_1968 67a8bb1c99734fc16b46f46813511518 316 SUPERFAMILY SSF53633 5 313 6.15E-69 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 SUPERFAMILY SSF56801 1 504 4.84E-139 T 23-10-2018 APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 395 473 4.7E-29 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 Pfam PF00501 AMP-binding enzyme 1 386 4.7E-69 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 117 128 - T 23-10-2018 IPR020845 AMP-binding, conserved site APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 Gene3D G3DSA:3.40.50.12780 1 380 1.3E-78 T 23-10-2018 APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 1 505 5.8E-222 T 23-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 PRINTS PR00154 AMP-binding signature 124 132 7.3E-5 T 23-10-2018 IPR020459 AMP-binding APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 PRINTS PR00154 AMP-binding signature 112 123 7.3E-5 T 23-10-2018 IPR020459 AMP-binding APE_2604 ca633f52d084e6ca22ecd4201b0e9d40 513 Gene3D G3DSA:3.30.300.30 383 511 1.9E-28 T 23-10-2018 APE_0784.1 02cee2963dd75a2d048244b87b566500 121 Pfam PF01047 MarR family 11 62 9.9E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APE_0784.1 02cee2963dd75a2d048244b87b566500 121 SUPERFAMILY SSF46785 8 64 9.26E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0784.1 02cee2963dd75a2d048244b87b566500 121 Gene3D G3DSA:1.10.10.10 4 75 3.0E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2248.1 2d78937a72183fd5b763a4784f61832a 405 Gene3D G3DSA:3.40.640.10 69 292 4.3E-123 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2248.1 2d78937a72183fd5b763a4784f61832a 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 242 255 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APE_2248.1 2d78937a72183fd5b763a4784f61832a 405 SUPERFAMILY SSF53383 25 400 3.86E-113 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2248.1 2d78937a72183fd5b763a4784f61832a 405 Pfam PF00155 Aminotransferase class I and II 38 393 2.9E-72 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APE_2248.1 2d78937a72183fd5b763a4784f61832a 405 Gene3D G3DSA:3.90.1150.10 32 393 4.3E-123 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_0141.1 3fc3f413ff974c4ac667090e8fad799b 400 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 172 303 1.6E-16 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 APE_0141.1 3fc3f413ff974c4ac667090e8fad799b 400 Gene3D G3DSA:3.30.750.80 75 180 5.8E-21 T 23-10-2018 APE_0141.1 3fc3f413ff974c4ac667090e8fad799b 400 SUPERFAMILY SSF53335 82 377 8.58E-45 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0141.1 3fc3f413ff974c4ac667090e8fad799b 400 Gene3D G3DSA:2.30.130.10 10 69 6.0E-7 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 APE_0141.1 3fc3f413ff974c4ac667090e8fad799b 400 Gene3D G3DSA:3.40.50.150 181 397 4.7E-45 T 23-10-2018 APE_0141.1 3fc3f413ff974c4ac667090e8fad799b 400 SUPERFAMILY SSF88697 12 68 1.14E-5 T 23-10-2018 IPR015947 PUA-like superfamily APE_0231 df6b384ffa2942140b3b94e431711659 287 Pfam PF00571 CBS domain 224 278 2.9E-13 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 Pfam PF00571 CBS domain 7 59 3.6E-14 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 Pfam PF00571 CBS domain 136 186 3.1E-5 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 Pfam PF00571 CBS domain 72 126 3.9E-13 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 SUPERFAMILY SSF54631 4 130 1.66E-33 T 23-10-2018 APE_0231 df6b384ffa2942140b3b94e431711659 287 Gene3D G3DSA:3.10.580.10 2 131 1.3E-36 T 23-10-2018 APE_0231 df6b384ffa2942140b3b94e431711659 287 SUPERFAMILY SSF54631 135 279 8.21E-23 T 23-10-2018 APE_0231 df6b384ffa2942140b3b94e431711659 287 Gene3D G3DSA:3.10.580.10 132 286 2.9E-25 T 23-10-2018 APE_0231 df6b384ffa2942140b3b94e431711659 287 SMART SM00116 79 127 1.3E-8 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 SMART SM00116 12 59 2.3E-14 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 SMART SM00116 231 278 7.2E-10 T 23-10-2018 IPR000644 CBS domain APE_0231 df6b384ffa2942140b3b94e431711659 287 SMART SM00116 143 190 1.6 T 23-10-2018 IPR000644 CBS domain APE_0943 2656adb392598b5a2433a513f38ee656 257 SUPERFAMILY SSF161098 13 251 5.79E-34 T 23-10-2018 IPR035906 MetI-like superfamily APE_0943 2656adb392598b5a2433a513f38ee656 257 Gene3D G3DSA:1.10.3720.10 9 255 7.0E-30 T 23-10-2018 IPR035906 MetI-like superfamily APE_0943 2656adb392598b5a2433a513f38ee656 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 247 1.6E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0498 727a33cdb560d9bc18bd7606ac63696a 357 Gene3D G3DSA:3.40.1280.30 111 240 1.9E-10 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily APE_0498 727a33cdb560d9bc18bd7606ac63696a 357 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 158 233 7.0E-5 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 APE_0498 727a33cdb560d9bc18bd7606ac63696a 357 PIRSF PIRSF018978 9 357 3.8E-130 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 APE_1328.1 89fd80a358cc181c419be00a2dffa9ce 680 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 178 1.3E-46 T 23-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 APE_1328.1 89fd80a358cc181c419be00a2dffa9ce 680 SUPERFAMILY SSF53067 5 490 6.48E-9 T 23-10-2018 APE_1328.1 89fd80a358cc181c419be00a2dffa9ce 680 Pfam PF01968 Hydantoinase/oxoprolinase 200 496 4.4E-96 T 23-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 Gene3D G3DSA:3.30.930.10 4 332 8.5E-112 T 23-10-2018 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 SUPERFAMILY SSF55681 7 330 1.73E-75 T 23-10-2018 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 Gene3D G3DSA:3.40.50.800 338 433 5.2E-13 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 SUPERFAMILY SSF52954 342 433 8.76E-15 T 23-10-2018 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 8 421 1.9E-112 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 Pfam PF03129 Anticodon binding domain 342 430 1.2E-13 T 23-10-2018 IPR004154 Anticodon-binding APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 PIRSF PIRSF001549 4 433 1.7E-130 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 Pfam PF13393 Histidyl-tRNA synthetase 11 323 5.9E-51 T 23-10-2018 APE_0662.1 83002eeb9b54a36ddccc14eb255265b1 435 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 4 431 27.353 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 SUPERFAMILY SSF69318 336 969 7.85E-6 T 23-10-2018 APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 SUPERFAMILY SSF52743 165 790 1.72E-44 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 Pfam PF00082 Subtilase family 182 778 4.5E-23 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 725 735 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 PRINTS PR00723 Subtilisin serine protease family (S8) signature 724 740 7.6E-11 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 PRINTS PR00723 Subtilisin serine protease family (S8) signature 182 201 7.6E-11 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_1213.1 76c4dd14f0a32552017e25f779f9e496 1362 Gene3D G3DSA:3.40.50.200 159 220 1.4E-6 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_1385 5bb6db103505c2626e45c9588b68ae6a 219 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 164 181 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 APE_1385 5bb6db103505c2626e45c9588b68ae6a 219 Gene3D G3DSA:3.40.1180.10 141 219 1.2E-19 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 APE_1385 5bb6db103505c2626e45c9588b68ae6a 219 Gene3D G3DSA:3.40.1180.10 2 121 2.5E-20 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 APE_1385 5bb6db103505c2626e45c9588b68ae6a 219 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 3 219 26.225 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 APE_1385 5bb6db103505c2626e45c9588b68ae6a 219 Pfam PF01255 Putative undecaprenyl diphosphate synthase 10 218 4.0E-31 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 APE_1385 5bb6db103505c2626e45c9588b68ae6a 219 SUPERFAMILY SSF64005 3 213 1.14E-38 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 APE_0091 49e877068a294998990bb1436f2d2df8 449 Pfam PF01523 Putative modulator of DNA gyrase 31 308 1.6E-37 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 APE_0091 49e877068a294998990bb1436f2d2df8 449 SUPERFAMILY SSF111283 16 438 1.44E-65 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 APE_0383.1 b63ed91bd42a58599aa390b09c9a3f2d 158 Pfam PF00571 CBS domain 78 132 2.8E-15 T 23-10-2018 IPR000644 CBS domain APE_0383.1 b63ed91bd42a58599aa390b09c9a3f2d 158 Pfam PF00571 CBS domain 12 66 6.0E-15 T 23-10-2018 IPR000644 CBS domain APE_0383.1 b63ed91bd42a58599aa390b09c9a3f2d 158 Gene3D G3DSA:3.10.580.10 5 156 3.2E-43 T 23-10-2018 APE_0383.1 b63ed91bd42a58599aa390b09c9a3f2d 158 SMART SM00116 19 67 1.0E-11 T 23-10-2018 IPR000644 CBS domain APE_0383.1 b63ed91bd42a58599aa390b09c9a3f2d 158 SMART SM00116 85 134 4.8E-14 T 23-10-2018 IPR000644 CBS domain APE_0383.1 b63ed91bd42a58599aa390b09c9a3f2d 158 SUPERFAMILY SSF54631 8 132 2.65E-38 T 23-10-2018 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 Gene3D G3DSA:3.60.21.10 1 257 1.0E-44 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 SUPERFAMILY SSF56300 1 220 6.01E-42 T 23-10-2018 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 SMART SM00156 1 257 2.4E-11 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 Pfam PF00149 Calcineurin-like phosphoesterase 1 198 3.8E-18 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 64 69 - T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 PRINTS PR00114 Serine/threonine phosphatase family signature 102 128 3.0E-9 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 PRINTS PR00114 Serine/threonine phosphatase family signature 28 55 3.0E-9 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 APE_0777 b7d08ce96f35cdabdb8ba24ceb4ea545 266 PRINTS PR00114 Serine/threonine phosphatase family signature 188 208 3.0E-9 T 23-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 APE_2265.1 2ad0811a78e62879539e1fc6868ae41e 292 SMART SM00849 15 200 6.0E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2265.1 2ad0811a78e62879539e1fc6868ae41e 292 Pfam PF00753 Metallo-beta-lactamase superfamily 18 200 8.2E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2265.1 2ad0811a78e62879539e1fc6868ae41e 292 SUPERFAMILY SSF56281 8 273 1.23E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_2265.1 2ad0811a78e62879539e1fc6868ae41e 292 Gene3D G3DSA:3.60.15.10 1 219 5.9E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 PIRSF PIRSF005856 1 319 3.8E-129 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 8 317 79.279 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 SMART SM00382 103 287 1.4E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 SUPERFAMILY SSF52540 83 317 1.76E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 10 317 3.9E-159 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 Gene3D G3DSA:3.40.50.300 70 319 3.1E-80 T 23-10-2018 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 SUPERFAMILY SSF47794 6 67 1.44E-12 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 Gene3D G3DSA:1.10.150.20 2 69 2.3E-21 T 23-10-2018 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 Pfam PF14520 Helix-hairpin-helix domain 9 64 5.9E-13 T 23-10-2018 APE_0119 5a750ddcc1c49e1b7cfed1bbbccaf857 319 Pfam PF08423 Rad51 69 317 8.6E-94 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 Pfam PF00171 Aldehyde dehydrogenase family 53 519 4.5E-100 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 Gene3D G3DSA:3.40.309.10 293 491 2.1E-199 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 SUPERFAMILY SSF53720 7 523 2.36E-122 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 10 537 8.4E-282 T 23-10-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 Gene3D G3DSA:3.40.605.10 13 523 2.1E-199 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 316 327 - T 23-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 APE_0807.1 d59d0c1dc709983d25db6ce90fa514d7 540 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 288 295 - T 23-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 APE_2617e.1 e3426cc7ba53074a34e427385ce57f70 80 SUPERFAMILY SSF46689 4 74 2.87E-17 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 APE_2617e.1 e3426cc7ba53074a34e427385ce57f70 80 Gene3D G3DSA:1.10.10.10 10 78 4.3E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2617e.1 e3426cc7ba53074a34e427385ce57f70 80 Pfam PF04255 Protein of unknown function (DUF433) 12 64 6.1E-19 T 23-10-2018 IPR007367 Protein of unknown function DUF433 APE_2338 05ba9bc82f0f7a020b33a3873f4ef659 316 Gene3D G3DSA:3.40.50.10790 4 179 1.2E-54 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal APE_2338 05ba9bc82f0f7a020b33a3873f4ef659 316 Gene3D G3DSA:2.40.30.90 186 283 8.9E-22 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal APE_2338 05ba9bc82f0f7a020b33a3873f4ef659 316 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 9 280 3.6E-75 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase APE_2338 05ba9bc82f0f7a020b33a3873f4ef659 316 SUPERFAMILY SSF101852 187 283 1.96E-22 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal APE_2338 05ba9bc82f0f7a020b33a3873f4ef659 316 PIRSF PIRSF006779 3 285 4.0E-113 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase APE_2338 05ba9bc82f0f7a020b33a3873f4ef659 316 SUPERFAMILY SSF102522 7 178 1.44E-48 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal APE_2164.1 17d75b2bfdc364164d0c7fc109221e24 123 Gene3D G3DSA:3.40.50.300 9 120 6.1E-19 T 23-10-2018 APE_2164.1 17d75b2bfdc364164d0c7fc109221e24 123 SUPERFAMILY SSF52540 10 82 1.67E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2164.1 17d75b2bfdc364164d0c7fc109221e24 123 Pfam PF02374 Anion-transporting ATPase 13 98 1.2E-14 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 Gene3D G3DSA:3.60.20.10 5 258 8.7E-83 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 SMART SM00948 12 34 8.7E-9 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 12 34 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 Pfam PF00227 Proteasome subunit 35 209 1.0E-59 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 7 248 45.825 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 10 248 1.3E-100 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 Pfam PF10584 Proteasome subunit A N-terminal signature 12 34 4.2E-11 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_1449 efd3fa1bda21f43b10c7433029703ca9 258 SUPERFAMILY SSF56235 9 254 4.07E-77 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_2221.1 02aa01fe7b6489ae12b0c0207972b965 361 SMART SM00327 184 361 2.8E-5 T 23-10-2018 IPR002035 von Willebrand factor, type A APE_2221.1 02aa01fe7b6489ae12b0c0207972b965 361 SUPERFAMILY SSF53300 184 317 3.77E-10 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_2221.1 02aa01fe7b6489ae12b0c0207972b965 361 Gene3D G3DSA:3.40.50.410 179 325 1.1E-5 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_2221.1 02aa01fe7b6489ae12b0c0207972b965 361 Pfam PF05762 VWA domain containing CoxE-like protein 132 347 3.2E-65 T 23-10-2018 IPR008912 Uncharacterised protein family CoxE-like APE_1380.1 91b68354a6f80c02fc7ad526b77b0346 312 SMART SM00382 28 212 3.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1380.1 91b68354a6f80c02fc7ad526b77b0346 312 Pfam PF00005 ABC transporter 21 163 5.2E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1380.1 91b68354a6f80c02fc7ad526b77b0346 312 Gene3D G3DSA:3.40.50.300 3 226 2.9E-52 T 23-10-2018 APE_1380.1 91b68354a6f80c02fc7ad526b77b0346 312 SUPERFAMILY SSF52540 7 223 5.52E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 SUPERFAMILY SSF53335 8 230 2.3E-51 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 21 232 45.357 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 SMART SM01206 7 233 8.9E-148 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 ProSitePatterns PS00566 Fibrillarin signature. 103 117 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PIRSF PIRSF006540 1 233 6.7E-100 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 Pfam PF01269 Fibrillarin 7 232 2.9E-102 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 78 99 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 210 231 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 51 70 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 103 120 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 28 47 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 158 187 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 PRINTS PR00052 Fibrillarin signature 128 157 7.2E-71 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 Gene3D G3DSA:3.30.200.20 1 55 1.1E-27 T 23-10-2018 APE_2196 a9efe8f354bfc3f9c3347bd846756fb6 233 Gene3D G3DSA:3.40.50.150 56 233 1.2E-69 T 23-10-2018 APE_1440a 9f1104ac28960ddc441981522e76af58 93 Gene3D G3DSA:3.30.310.50 1 76 2.4E-12 T 23-10-2018 APE_1440a 9f1104ac28960ddc441981522e76af58 93 Pfam PF09341 Transcription factor Pcc1 13 69 2.7E-4 T 23-10-2018 IPR015419 CTAG/Pcc1 family APE_2414.1 9c381827fc81dfd04e895d3940bb787d 475 PIRSF PIRSF006603 4 458 1.7E-114 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_2414.1 9c381827fc81dfd04e895d3940bb787d 475 Pfam PF01554 MatE 251 412 7.4E-25 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_2414.1 9c381827fc81dfd04e895d3940bb787d 475 Pfam PF01554 MatE 28 188 3.1E-21 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_2414.1 9c381827fc81dfd04e895d3940bb787d 475 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 425 2.2E-73 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_2089 9715a49421c6a3511db5871af3051fd1 132 Gene3D G3DSA:3.50.30.10 3 129 6.5E-36 T 23-10-2018 APE_2089 9715a49421c6a3511db5871af3051fd1 132 SUPERFAMILY SSF52016 6 122 2.75E-33 T 23-10-2018 APE_2089 9715a49421c6a3511db5871af3051fd1 132 Hamap MF_00078 UPF0107 protein . 5 127 27.564 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative APE_2089 9715a49421c6a3511db5871af3051fd1 132 Pfam PF01989 Protein of unknown function DUF126 26 98 3.1E-24 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative APE_2089 9715a49421c6a3511db5871af3051fd1 132 PIRSF PIRSF004966 3 129 2.5E-43 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative APE_0084.1 e4435da5e0717c8ea45e64d494e39b44 237 Pfam PF00881 Nitroreductase family 11 164 2.2E-16 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APE_0084.1 e4435da5e0717c8ea45e64d494e39b44 237 SUPERFAMILY SSF55469 9 227 2.09E-44 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APE_0084.1 e4435da5e0717c8ea45e64d494e39b44 237 PIRSF PIRSF005426 3 236 7.8E-60 T 23-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 APE_0084.1 e4435da5e0717c8ea45e64d494e39b44 237 Gene3D G3DSA:3.40.109.10 7 237 3.3E-44 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 Pfam PF01564 Spermine/spermidine synthase domain 69 250 9.7E-48 T 23-10-2018 APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 SUPERFAMILY SSF53335 10 297 5.99E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 Gene3D G3DSA:2.30.140.10 13 63 4.8E-13 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 Gene3D G3DSA:3.40.50.150 65 313 1.2E-77 T 23-10-2018 APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 90 103 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 14 298 36.045 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APE_0767.1 967c6e74313f0b63c9a80aa7c5f1219b 314 Pfam PF17284 Spermidine synthase tetramerisation domain 15 66 5.3E-9 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 APE_0349 4a50adc0655761259c85e754a67debfd 145 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 22 145 26.827 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 APE_0349 4a50adc0655761259c85e754a67debfd 145 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 52 145 8.0E-49 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0349 4a50adc0655761259c85e754a67debfd 145 ProSitePatterns PS00580 Ribosomal protein L32e signature. 41 63 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0349 4a50adc0655761259c85e754a67debfd 145 SUPERFAMILY SSF52042 23 145 8.76E-39 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0349 4a50adc0655761259c85e754a67debfd 145 SMART SM01393 38 145 1.1E-52 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0349 4a50adc0655761259c85e754a67debfd 145 Pfam PF01655 Ribosomal protein L32 39 145 1.8E-33 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1514.1 416713acf1a198aa8c6f73c96106ada5 247 SUPERFAMILY SSF53448 5 229 4.28E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1514.1 416713acf1a198aa8c6f73c96106ada5 247 Pfam PF12804 MobA-like NTP transferase domain 5 126 3.1E-10 T 23-10-2018 IPR025877 MobA-like NTP transferase APE_1514.1 416713acf1a198aa8c6f73c96106ada5 247 Gene3D G3DSA:3.90.550.10 2 232 2.1E-25 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0603 d56e51afc33d9ed5e03fe04127791aa2 249 SUPERFAMILY SSF54690 106 226 2.35E-28 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 APE_0603 d56e51afc33d9ed5e03fe04127791aa2 249 Gene3D G3DSA:3.10.20.30 5 90 1.9E-7 T 23-10-2018 IPR012675 Beta-grasp domain superfamily APE_0603 d56e51afc33d9ed5e03fe04127791aa2 249 Gene3D G3DSA:3.90.1170.40 96 232 2.5E-26 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 APE_0603 d56e51afc33d9ed5e03fe04127791aa2 249 SUPERFAMILY SSF54285 6 90 9.48E-6 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp APE_0603 d56e51afc33d9ed5e03fe04127791aa2 249 Pfam PF02391 MoaE protein 103 214 3.8E-20 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 APE_1184 907952d672ba4ba957c8e7a99df55d99 357 Pfam PF00535 Glycosyl transferase family 2 7 143 7.8E-15 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APE_1184 907952d672ba4ba957c8e7a99df55d99 357 SUPERFAMILY SSF53448 2 297 3.16E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1184 907952d672ba4ba957c8e7a99df55d99 357 Gene3D G3DSA:3.90.550.10 2 243 9.3E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Pfam PF00378 Enoyl-CoA hydratase/isomerase 421 668 5.2E-72 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Gene3D G3DSA:1.10.1040.10 200 311 1.5E-24 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Gene3D G3DSA:1.10.1040.10 316 404 1.5E-26 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 SUPERFAMILY SSF52096 410 669 4.15E-91 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 195 3.7E-64 T 23-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 SUPERFAMILY SSF48179 317 421 4.08E-26 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 320 405 8.7E-23 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 198 292 1.7E-25 T 23-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 SUPERFAMILY SSF51735 5 194 4.3E-57 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Gene3D G3DSA:1.10.12.10 611 669 5.3E-21 T 23-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Gene3D G3DSA:3.90.226.10 405 610 3.2E-72 T 23-10-2018 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 SUPERFAMILY SSF48179 197 304 4.76E-23 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APE_1484.1 f234da8f92a721c4cd0f4a5adb6f25cc 669 Gene3D G3DSA:3.40.50.720 2 199 2.7E-68 T 23-10-2018 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 Gene3D G3DSA:1.10.1670.10 15 221 3.5E-60 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 SMART SM00478 45 199 4.6E-32 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 201 217 3.0E-7 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 41 171 1.4E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 PIRSF PIRSF001435 8 223 9.9E-31 T 23-10-2018 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 Gene3D G3DSA:1.10.340.30 27 139 3.5E-60 T 23-10-2018 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 SUPERFAMILY SSF48150 9 222 6.6E-60 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APE_0875.1 6172dcebd5bc0a7faa053b896b640a9a 223 SMART SM00525 200 220 1.7E-8 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 APE_0525b c5cce902066fbbfa675733a26e23380b 62 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0525b c5cce902066fbbfa675733a26e23380b 62 Gene3D G3DSA:2.20.25.30 1 56 1.0E-22 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0525b c5cce902066fbbfa675733a26e23380b 62 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 22.156 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0525b c5cce902066fbbfa675733a26e23380b 62 SUPERFAMILY SSF57829 1 56 1.15E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APE_0525b c5cce902066fbbfa675733a26e23380b 62 Pfam PF01907 Ribosomal protein L37e 3 55 7.4E-25 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0525b c5cce902066fbbfa675733a26e23380b 62 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 16 51 8.0E-14 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 PIRSF PIRSF000149 2 322 3.4E-76 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 343 166.368 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 Gene3D G3DSA:3.30.360.10 140 337 8.7E-127 T 23-10-2018 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 108 9.3E-11 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 147 300 9.3E-19 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 SUPERFAMILY SSF51735 4 161 1.54E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 SUPERFAMILY SSF55347 142 303 2.7E-47 T 23-10-2018 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 6 338 2.3E-128 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 140 147 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 SMART SM00846 4 142 2.2E-13 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0171.1 ba6a1984e11b8353be9327357a70a854 343 Gene3D G3DSA:3.40.50.720 6 331 8.7E-127 T 23-10-2018 APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 Pfam PF00276 Ribosomal protein L23 5 75 5.9E-18 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 Gene3D G3DSA:3.30.70.330 3 86 1.2E-33 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 SUPERFAMILY SSF54189 2 82 2.66E-25 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 11 85 3.1E-36 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 25.898 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 13.818 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 APE_0228a.1 d0efc74779b6d21fc481af19e2a63fb8 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 SUPERFAMILY SSF47954 206 299 5.35E-16 T 23-10-2018 IPR036915 Cyclin-like superfamily APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 Pfam PF00382 Transcription factor TFIIB repeat 210 286 4.3E-9 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 9.3E-7 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 PRINTS PR00685 Transcription initiation factor IIB signature 140 159 9.3E-7 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 PRINTS PR00685 Transcription initiation factor IIB signature 11 31 9.3E-7 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 9.3E-7 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 SUPERFAMILY SSF47954 95 180 5.1E-11 T 23-10-2018 IPR036915 Cyclin-like superfamily APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 Gene3D G3DSA:1.10.472.170 3 181 3.6E-15 T 23-10-2018 APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 SMART SM00385 98 179 4.9 T 23-10-2018 IPR013763 Cyclin-like APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 SMART SM00385 208 295 2.1E-4 T 23-10-2018 IPR013763 Cyclin-like APE_0787.1 4ddcb183726a50d9ce9e0be09f25b41f 303 Gene3D G3DSA:1.10.472.10 206 301 1.6E-15 T 23-10-2018 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00102 Ornithine carbamoyltransferase signature 126 140 4.2E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00102 Ornithine carbamoyltransferase signature 292 303 4.2E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00102 Ornithine carbamoyltransferase signature 53 67 4.2E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00102 Ornithine carbamoyltransferase signature 86 99 4.2E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00102 Ornithine carbamoyltransferase signature 230 240 4.2E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 8 314 81.811 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 55 62 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 311 8.1E-57 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 SUPERFAMILY SSF53671 4 313 1.83E-105 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 Gene3D G3DSA:3.40.50.1370 9 152 8.4E-121 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 137 148 1.6E-26 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 55 74 1.6E-26 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 266 275 1.6E-26 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 278 301 1.6E-26 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 Gene3D G3DSA:3.40.50.1370 153 309 8.4E-121 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 150 1.3E-47 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 APE_1992.1 62b404e9ac55448e63c8c58e0f740fc8 314 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 9 312 1.4E-126 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 APE_0077 1bf5ce4c0f63ef842847ff4f095b9ffc 171 Gene3D G3DSA:3.40.980.10 9 170 2.2E-36 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_0077 1bf5ce4c0f63ef842847ff4f095b9ffc 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 15 155 4.6E-25 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0077 1bf5ce4c0f63ef842847ff4f095b9ffc 171 Pfam PF00994 Probable molybdopterin binding domain 17 156 1.2E-29 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0077 1bf5ce4c0f63ef842847ff4f095b9ffc 171 PIRSF PIRSF006443 1 170 2.8E-45 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 APE_0077 1bf5ce4c0f63ef842847ff4f095b9ffc 171 SMART SM00852 16 162 6.8E-21 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0077 1bf5ce4c0f63ef842847ff4f095b9ffc 171 SUPERFAMILY SSF53218 14 167 2.09E-32 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_2505 29083ea5bcb09c00a36d981b66325f3e 153 SUPERFAMILY SSF46785 90 143 2.77E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2505 29083ea5bcb09c00a36d981b66325f3e 153 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 95 141 8.7E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal APE_2505 29083ea5bcb09c00a36d981b66325f3e 153 Gene3D G3DSA:1.10.10.10 90 150 4.4E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2505 29083ea5bcb09c00a36d981b66325f3e 153 SMART SM00418 88 151 0.0072 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 21 227 6.0E-43 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 Gene3D G3DSA:3.20.20.70 2 235 6.6E-84 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 Pfam PF01791 DeoC/LacD family aldolase 33 202 1.1E-7 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 SMART SM01133 20 230 1.2E-51 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 SUPERFAMILY SSF51569 16 232 1.15E-51 T 23-10-2018 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 PIRSF PIRSF001357 16 234 1.7E-57 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_2437.1 e409701760f16ae72a6d1354a868e65d 235 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 19 232 26.686 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 APE_1226 68d031484a6c3688bcef6aca6e7ab1ce 384 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 382 7.7E-154 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APE_1226 68d031484a6c3688bcef6aca6e7ab1ce 384 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 191 205 - T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APE_1226 68d031484a6c3688bcef6aca6e7ab1ce 384 SUPERFAMILY SSF53383 28 383 8.43E-128 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_1226 68d031484a6c3688bcef6aca6e7ab1ce 384 PIRSF PIRSF001434 1 384 1.2E-156 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 APE_1226 68d031484a6c3688bcef6aca6e7ab1ce 384 Gene3D G3DSA:3.90.1150.10 250 384 4.4E-60 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_1226 68d031484a6c3688bcef6aca6e7ab1ce 384 Gene3D G3DSA:3.40.640.10 1 249 3.8E-98 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1407.1 540640e86dce3a279aadb7606b42aebb 266 SUPERFAMILY SSF144020 11 240 1.7E-28 T 23-10-2018 IPR024064 FdhE-like superfamily APE_1407.1 540640e86dce3a279aadb7606b42aebb 266 Gene3D G3DSA:3.90.1670.10 115 244 5.6E-5 T 23-10-2018 IPR024064 FdhE-like superfamily APE_0169.1 ffd93d3afb177a02b757b67a74b3bacc 403 Gene3D G3DSA:3.90.1150.10 20 398 2.4E-128 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_0169.1 ffd93d3afb177a02b757b67a74b3bacc 403 SUPERFAMILY SSF53383 3 400 5.17E-102 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_0169.1 ffd93d3afb177a02b757b67a74b3bacc 403 Gene3D G3DSA:3.40.640.10 67 292 2.4E-128 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_0169.1 ffd93d3afb177a02b757b67a74b3bacc 403 Pfam PF00155 Aminotransferase class I and II 60 388 3.5E-37 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APE_1633 4fbc9040c47871edc2fc8a68d08470c5 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 258 4.2E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1633 4fbc9040c47871edc2fc8a68d08470c5 270 SUPERFAMILY SSF161098 7 263 6.82E-47 T 23-10-2018 IPR035906 MetI-like superfamily APE_1633 4fbc9040c47871edc2fc8a68d08470c5 270 Gene3D G3DSA:1.10.3720.10 3 263 2.3E-41 T 23-10-2018 IPR035906 MetI-like superfamily APE_2384 d847da02c60a9a9478f77a9835bc735e 394 PIRSF PIRSF000429 8 391 1.6E-28 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_2384 d847da02c60a9a9478f77a9835bc735e 394 SUPERFAMILY SSF53901 238 387 6.33E-19 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2384 d847da02c60a9a9478f77a9835bc735e 394 Gene3D G3DSA:3.40.47.10 7 394 1.2E-91 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_2384 d847da02c60a9a9478f77a9835bc735e 394 SUPERFAMILY SSF53901 13 235 6.19E-31 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 Gene3D G3DSA:3.40.50.11860 239 343 1.0E-26 T 23-10-2018 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 14 343 6.0E-81 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 Gene3D G3DSA:3.40.50.11850 125 233 5.6E-28 T 23-10-2018 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 Pfam PF01866 Putative diphthamide synthesis protein 37 344 2.9E-60 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 Gene3D G3DSA:3.40.50.11840 18 118 1.1E-16 T 23-10-2018 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 30 352 7.9E-97 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 APE_0447.1 9956abb3bf01464d5d56f827104d9606 354 PIRSF PIRSF004967 1 354 2.3E-89 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_0410.1 c72625a6ceb95588681c97ea7a11c07e 102 Gene3D G3DSA:3.40.50.10580 6 102 7.3E-9 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0410.1 c72625a6ceb95588681c97ea7a11c07e 102 SUPERFAMILY SSF159468 8 101 1.18E-11 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0410.1 c72625a6ceb95588681c97ea7a11c07e 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 8 87 1.0E-8 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_1343 f6828a45b4e60d30c1b07e2345d039b4 306 Gene3D G3DSA:3.60.110.10 1 289 7.6E-28 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APE_1343 f6828a45b4e60d30c1b07e2345d039b4 306 SUPERFAMILY SSF56317 1 259 6.41E-27 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APE_1343 f6828a45b4e60d30c1b07e2345d039b4 306 Pfam PF00795 Carbon-nitrogen hydrolase 11 190 1.1E-12 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APE_1937.1 d85a44cfb8c9efcbb4c1ad7a0e60096f 262 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 69 251 2.0E-99 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase APE_1937.1 d85a44cfb8c9efcbb4c1ad7a0e60096f 262 PIRSF PIRSF004853 5 258 5.8E-96 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase APE_1937.1 d85a44cfb8c9efcbb4c1ad7a0e60096f 262 Gene3D G3DSA:3.40.50.12640 5 262 2.1E-95 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily APE_1937.1 d85a44cfb8c9efcbb4c1ad7a0e60096f 262 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 69 247 1.7E-66 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase APE_2413 8303cdffa26d8c46ac76e7e70821c380 116 Gene3D G3DSA:1.10.10.10 21 109 2.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2413 8303cdffa26d8c46ac76e7e70821c380 116 SUPERFAMILY SSF46785 23 102 6.07E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2413 8303cdffa26d8c46ac76e7e70821c380 116 Pfam PF01022 Bacterial regulatory protein, arsR family 33 77 1.6E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_1728 225de1ce026c97b14823de1674b3886c 517 Pfam PF01547 Bacterial extracellular solute-binding protein 99 356 1.3E-27 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein APE_1728 225de1ce026c97b14823de1674b3886c 517 Gene3D G3DSA:3.40.190.10 200 385 6.3E-38 T 23-10-2018 APE_1728 225de1ce026c97b14823de1674b3886c 517 Gene3D G3DSA:3.40.190.10 131 378 6.3E-38 T 23-10-2018 APE_1728 225de1ce026c97b14823de1674b3886c 517 SUPERFAMILY SSF53850 114 380 1.34E-47 T 23-10-2018 APE_1065.1 8294143e504fdd72feb38b390b013965 378 Gene3D G3DSA:3.40.50.261 237 378 1.8E-49 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1065.1 8294143e504fdd72feb38b390b013965 378 Pfam PF00549 CoA-ligase 260 367 4.3E-14 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1065.1 8294143e504fdd72feb38b390b013965 378 SUPERFAMILY SSF56059 2 228 3.12E-54 T 23-10-2018 APE_1065.1 8294143e504fdd72feb38b390b013965 378 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 377 6.7E-118 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1065.1 8294143e504fdd72feb38b390b013965 378 PIRSF PIRSF001554 1 378 1.9E-127 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1065.1 8294143e504fdd72feb38b390b013965 378 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 253 278 - T 23-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1065.1 8294143e504fdd72feb38b390b013965 378 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 377 34.469 T 23-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1065.1 8294143e504fdd72feb38b390b013965 378 SUPERFAMILY SSF52210 236 378 1.44E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1065.1 8294143e504fdd72feb38b390b013965 378 Gene3D G3DSA:3.30.470.20 1 224 7.5E-63 T 23-10-2018 APE_1065.1 8294143e504fdd72feb38b390b013965 378 Gene3D G3DSA:3.30.1490.20 21 98 7.5E-63 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APE_1065.1 8294143e504fdd72feb38b390b013965 378 Pfam PF08442 ATP-grasp domain 2 196 2.4E-50 T 23-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1984.1 3ad00920861cfe290fe03ca7757f9f5b 194 Gene3D G3DSA:3.40.630.30 10 159 3.3E-14 T 23-10-2018 APE_1984.1 3ad00920861cfe290fe03ca7757f9f5b 194 SUPERFAMILY SSF55729 27 127 1.32E-16 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_1984.1 3ad00920861cfe290fe03ca7757f9f5b 194 Pfam PF08445 FR47-like protein 62 125 2.4E-9 T 23-10-2018 IPR013653 FR47-like GO:0016747 APE_0306.1 3e845044534673944c7e4d36080614ae 475 SUPERFAMILY SSF53067 7 228 1.06E-25 T 23-10-2018 APE_0306.1 3e845044534673944c7e4d36080614ae 475 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 235 416 2.8E-14 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 APE_0306.1 3e845044534673944c7e4d36080614ae 475 SUPERFAMILY SSF53067 227 437 1.61E-27 T 23-10-2018 APE_0306.1 3e845044534673944c7e4d36080614ae 475 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 202 7.0E-10 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 APE_0306.1 3e845044534673944c7e4d36080614ae 475 Gene3D G3DSA:3.30.420.40 3 225 7.5E-24 T 23-10-2018 APE_0306.1 3e845044534673944c7e4d36080614ae 475 Gene3D G3DSA:3.30.420.40 227 440 8.8E-31 T 23-10-2018 APE_0306.1 3e845044534673944c7e4d36080614ae 475 PIRSF PIRSF000538 3 440 3.1E-39 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 APE_0132.1 1589e645dfe92bc0ac28a38247c1a74e 104 Gene3D G3DSA:3.30.1860.10 1 102 7.6E-14 T 23-10-2018 APE_0132.1 1589e645dfe92bc0ac28a38247c1a74e 104 Pfam PF04242 Protein of unknown function (DUF424) 10 101 8.2E-23 T 23-10-2018 IPR007355 Protein of unknown function DUF424 APE_0496.1 49666c2eac7a6a0849237d42a0b609da 225 Gene3D G3DSA:3.30.420.10 2 206 3.3E-53 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APE_0496.1 49666c2eac7a6a0849237d42a0b609da 225 SUPERFAMILY SSF53098 3 205 3.03E-47 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily APE_0496.1 49666c2eac7a6a0849237d42a0b609da 225 Hamap MF_00052_A Ribonuclease HII [rnhB]. 3 206 30.08 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 APE_0496.1 49666c2eac7a6a0849237d42a0b609da 225 Pfam PF01351 Ribonuclease HII 5 201 1.8E-42 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain APE_0496.1 49666c2eac7a6a0849237d42a0b609da 225 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 4 205 1.1E-78 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 6 192 7.0E-52 T 23-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 Pfam PF00117 Glutamine amidotransferase class-I 7 191 1.6E-51 T 23-10-2018 IPR017926 Glutamine amidotransferase APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 98 115 2.2E-10 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 2.2E-10 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 48 62 2.2E-10 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 Gene3D G3DSA:3.40.50.880 3 192 1.1E-65 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00097 Anthranilate synthase component II signature 51 60 9.1E-33 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00097 Anthranilate synthase component II signature 126 138 9.1E-33 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00097 Anthranilate synthase component II signature 6 20 9.1E-33 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00097 Anthranilate synthase component II signature 170 183 9.1E-33 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00097 Anthranilate synthase component II signature 81 92 9.1E-33 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00097 Anthranilate synthase component II signature 106 114 9.1E-33 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 3.0E-15 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 170 183 3.0E-15 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 PRINTS PR00096 Glutamine amidotransferase superfamily signature 51 60 3.0E-15 T 23-10-2018 APE_2555 cdfb9f336a755fbe10183c1d20df7cfb 196 SUPERFAMILY SSF52317 5 192 2.75E-57 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 SUPERFAMILY SSF53738 154 259 7.85E-21 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Gene3D G3DSA:3.30.310.50 375 455 5.4E-19 T 23-10-2018 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 5 451 6.5E-156 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 SUPERFAMILY SSF55957 362 457 5.36E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 392 452 6.0E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 371 1.8E-17 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 SUPERFAMILY SSF53738 3 181 5.89E-45 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Gene3D G3DSA:3.40.120.10 257 366 4.0E-52 T 23-10-2018 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 5.5E-22 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 2.9E-13 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 2.9E-13 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 2.9E-13 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 2.9E-13 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 SUPERFAMILY SSF53738 245 374 1.84E-17 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Gene3D G3DSA:3.40.120.10 176 361 4.0E-52 T 23-10-2018 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 93 102 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 134 6.6E-44 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 APE_0317.1 ba4a21b86a313ed39f358812d4095128 464 Gene3D G3DSA:3.40.120.10 4 152 2.6E-51 T 23-10-2018 APE_2252.1 212f2ceb123f8a0184eda7ea9d1ff038 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 289 2.0E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_2252.1 212f2ceb123f8a0184eda7ea9d1ff038 302 Gene3D G3DSA:1.10.3720.10 13 290 2.7E-47 T 23-10-2018 IPR035906 MetI-like superfamily APE_2252.1 212f2ceb123f8a0184eda7ea9d1ff038 302 SUPERFAMILY SSF161098 16 295 3.08E-47 T 23-10-2018 IPR035906 MetI-like superfamily APE_1270.1 0d0c5967d5662fe44e3dd2aecd43b5c5 149 SUPERFAMILY SSF81301 23 99 2.9E-16 T 23-10-2018 APE_1270.1 0d0c5967d5662fe44e3dd2aecd43b5c5 149 Pfam PF01909 Nucleotidyltransferase domain 24 93 9.9E-14 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 APE_1270.1 0d0c5967d5662fe44e3dd2aecd43b5c5 149 Gene3D G3DSA:3.30.460.10 8 104 1.6E-18 T 23-10-2018 APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 Pfam PF00578 AhpC/TSA family 8 139 3.5E-31 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 PIRSF PIRSF000239 1 225 9.6E-72 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 Hamap MF_00401 Peroxiredoxin. 6 217 53.518 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 SUPERFAMILY SSF52833 4 234 1.3E-69 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 203 8.2E-10 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 Gene3D G3DSA:3.40.30.10 2 146 3.5E-46 T 23-10-2018 APE_2278 2387dc3a5bfc66205a3d98ad79bb6f5a 250 Gene3D G3DSA:3.30.1020.20 147 250 4.4E-51 T 23-10-2018 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 Gene3D G3DSA:3.40.50.620 176 371 2.3E-44 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 176 358 5.9E-45 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 SMART SM00981 77 166 6.8E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 SUPERFAMILY SSF52402 176 334 1.01E-32 T 23-10-2018 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 Gene3D G3DSA:3.30.2130.30 1 175 1.3E-38 T 23-10-2018 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 Pfam PF02926 THUMP domain 32 162 4.6E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 SUPERFAMILY SSF143437 3 174 1.92E-37 T 23-10-2018 APE_0465.1 7ea7a20b389a826ea93c92e4f6adcdc9 396 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 396 110.804 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 APE_1586 e712b2036ef08433f0741e5c0fdf88de 389 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 115 134 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 APE_1586 e712b2036ef08433f0741e5c0fdf88de 389 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 94 367 2.9E-48 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_1586 e712b2036ef08433f0741e5c0fdf88de 389 Gene3D G3DSA:3.40.50.1100 97 376 1.4E-93 T 23-10-2018 APE_1586 e712b2036ef08433f0741e5c0fdf88de 389 Gene3D G3DSA:3.40.50.1100 129 228 1.4E-93 T 23-10-2018 APE_1586 e712b2036ef08433f0741e5c0fdf88de 389 Gene3D G3DSA:3.90.1530.20 1 78 1.2E-50 T 23-10-2018 APE_1586 e712b2036ef08433f0741e5c0fdf88de 389 SUPERFAMILY SSF53686 90 382 1.44E-64 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_1911.1 6273f361fae4500b3aa0b6801767f6e3 294 SUPERFAMILY SSF52540 3 219 3.94E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1911.1 6273f361fae4500b3aa0b6801767f6e3 294 SMART SM00382 29 207 3.8E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1911.1 6273f361fae4500b3aa0b6801767f6e3 294 Pfam PF00005 ABC transporter 20 159 4.9E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1911.1 6273f361fae4500b3aa0b6801767f6e3 294 Gene3D G3DSA:3.40.50.300 2 239 1.1E-56 T 23-10-2018 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 Gene3D G3DSA:3.40.50.300 103 307 4.4E-78 T 23-10-2018 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 Gene3D G3DSA:1.20.120.140 4 94 3.3E-17 T 23-10-2018 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 32 308 57.445 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 SMART SM00382 112 297 8.7E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 Pfam PF00448 SRP54-type protein, GTPase domain 114 308 8.5E-74 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 SMART SM00962 113 308 2.1E-105 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 SUPERFAMILY SSF52540 111 307 1.55E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 Pfam PF02881 SRP54-type protein, helical bundle domain 26 85 1.4E-8 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 SMART SM00963 5 89 8.1E-6 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 281 294 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 35 307 4.6E-95 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 APE_1081.1 940280e7c682645c04a421b8cd4c9580 308 SUPERFAMILY SSF47364 2 97 2.22E-11 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 APE_2586.1 781ee46695b58b62c0e7a398b362bcff 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 19 273 3.1E-33 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 39 51 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 60 76 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 88 96 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 7 527 5.5E-235 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 Gene3D G3DSA:3.30.260.10 146 407 2.4E-199 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 Gene3D G3DSA:1.10.560.10 27 525 2.4E-199 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 Pfam PF00118 TCP-1/cpn60 chaperonin family 34 528 1.7E-180 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 36 52 2.6E-33 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 375 397 2.6E-33 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 88 107 2.6E-33 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 409 421 2.6E-33 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 58 76 2.6E-33 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 SUPERFAMILY SSF48592 16 528 1.3E-89 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 SUPERFAMILY SSF54849 145 406 3.05E-25 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 Gene3D G3DSA:3.50.7.10 220 371 2.4E-199 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily APE_0907.1 1be82d8ae758356a7a357d51ab4178ad 554 SUPERFAMILY SSF52029 214 380 9.0E-61 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Gene3D G3DSA:3.40.50.880 2 201 1.7E-48 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Pfam PF02540 NAD synthase 208 288 6.8E-6 T 23-10-2018 IPR022310 NAD/GMP synthase APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Pfam PF00117 Glutamine amidotransferase class-I 12 189 2.1E-31 T 23-10-2018 IPR017926 Glutamine amidotransferase APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 82 93 6.9E-9 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 6.9E-9 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00096 Glutamine amidotransferase superfamily signature 55 64 6.9E-9 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Gene3D G3DSA:3.30.300.10 393 512 3.1E-47 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 SUPERFAMILY SSF52402 193 434 9.21E-46 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 512 48.63 T 23-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Gene3D G3DSA:3.40.50.620 202 392 3.7E-66 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 Pfam PF00958 GMP synthase C terminal domain 420 511 4.1E-37 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 203 512 5.8E-144 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 192 9.6E-70 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 4.8E-7 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 82 98 4.8E-7 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 52 66 4.8E-7 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00097 Anthranilate synthase component II signature 82 93 4.1E-7 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00097 Anthranilate synthase component II signature 55 64 4.1E-7 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 PRINTS PR00097 Anthranilate synthase component II signature 169 182 4.1E-7 T 23-10-2018 APE_2452 3c3e5367e4b88f7fea2f17a97b8a92f1 512 SUPERFAMILY SSF52317 10 193 4.86E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_1517 2b9232e65607d2f1412d7a2526bb53d2 392 PIRSF PIRSF015578 1 392 2.1E-99 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 APE_1517 2b9232e65607d2f1412d7a2526bb53d2 392 SUPERFAMILY SSF51735 2 373 1.65E-53 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1517 2b9232e65607d2f1412d7a2526bb53d2 392 Gene3D G3DSA:3.40.50.720 3 356 4.2E-102 T 23-10-2018 APE_1517 2b9232e65607d2f1412d7a2526bb53d2 392 Gene3D G3DSA:3.30.360.10 218 321 4.2E-102 T 23-10-2018 APE_1517 2b9232e65607d2f1412d7a2526bb53d2 392 SUPERFAMILY SSF55347 213 318 1.31E-28 T 23-10-2018 APE_1517 2b9232e65607d2f1412d7a2526bb53d2 392 Pfam PF01658 Myo-inositol-1-phosphate synthase 214 319 5.3E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 APE_2171.1 d258c862ebd615cf59987221ab3a8f5d 341 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 11 291 31.654 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea APE_2171.1 d258c862ebd615cf59987221ab3a8f5d 341 SUPERFAMILY SSF160369 13 145 5.36E-20 T 23-10-2018 APE_2171.1 d258c862ebd615cf59987221ab3a8f5d 341 Gene3D G3DSA:3.90.105.20 114 193 2.5E-53 T 23-10-2018 APE_2171.1 d258c862ebd615cf59987221ab3a8f5d 341 Pfam PF00466 Ribosomal protein L10 15 111 5.4E-19 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 APE_2171.1 d258c862ebd615cf59987221ab3a8f5d 341 Gene3D G3DSA:3.30.70.1730 25 215 2.5E-53 T 23-10-2018 APE_2585 898267bac3ea25be3d7031d4448f3996 348 Pfam PF00753 Metallo-beta-lactamase superfamily 18 236 1.9E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2585 898267bac3ea25be3d7031d4448f3996 348 SUPERFAMILY SSF56281 15 329 4.72E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_2585 898267bac3ea25be3d7031d4448f3996 348 SMART SM00849 20 236 6.4E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2585 898267bac3ea25be3d7031d4448f3996 348 Gene3D G3DSA:3.60.15.10 7 263 2.6E-47 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0365 1650f093b7d58a7321eb09338f80a441 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 129 153 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0365 1650f093b7d58a7321eb09338f80a441 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 6 155 1.9E-69 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0365 1650f093b7d58a7321eb09338f80a441 156 Pfam PF00237 Ribosomal protein L22p/L17e 19 153 1.1E-31 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 APE_0365 1650f093b7d58a7321eb09338f80a441 156 Gene3D G3DSA:3.90.470.10 4 156 4.7E-52 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 APE_0365 1650f093b7d58a7321eb09338f80a441 156 SUPERFAMILY SSF54843 4 155 7.59E-49 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 APE_0365 1650f093b7d58a7321eb09338f80a441 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 156 34.652 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 308 4.0E-21 T 23-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 SUPERFAMILY SSF52518 3 172 5.89E-46 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 Gene3D G3DSA:3.40.50.1220 194 359 1.2E-27 T 23-10-2018 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 Gene3D G3DSA:3.40.50.970 1 185 4.9E-48 T 23-10-2018 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 170 6.1E-46 T 23-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 SUPERFAMILY SSF52518 369 546 1.16E-43 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 Gene3D G3DSA:3.40.50.970 360 551 1.8E-44 T 23-10-2018 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 536 4.8E-28 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APE_2509 66c772ce1f3c8c7d42c65030690525e1 556 SUPERFAMILY SSF52467 196 356 2.8E-28 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APE_2055.1 dc9ade6da570cff43ac225764ccaa741 299 Gene3D G3DSA:3.60.110.10 4 270 5.0E-30 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APE_2055.1 dc9ade6da570cff43ac225764ccaa741 299 Pfam PF00795 Carbon-nitrogen hydrolase 6 257 7.6E-19 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APE_2055.1 dc9ade6da570cff43ac225764ccaa741 299 SUPERFAMILY SSF56317 1 260 1.83E-39 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APE_1528.1 4ff62e2455c46af6c7f27982277fa512 389 Gene3D G3DSA:3.40.50.2000 177 357 6.1E-24 T 23-10-2018 APE_1528.1 4ff62e2455c46af6c7f27982277fa512 389 Pfam PF13692 Glycosyl transferases group 1 205 341 1.1E-6 T 23-10-2018 APE_1528.1 4ff62e2455c46af6c7f27982277fa512 389 Gene3D G3DSA:3.40.50.2000 10 373 6.1E-24 T 23-10-2018 APE_1528.1 4ff62e2455c46af6c7f27982277fa512 389 SUPERFAMILY SSF53756 6 377 1.94E-29 T 23-10-2018 APE_1596 8e9c22a8a63a49c4f4f52e71775cba55 406 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 2 406 51.032 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 APE_1596 8e9c22a8a63a49c4f4f52e71775cba55 406 Gene3D G3DSA:3.30.300.280 157 399 2.0E-155 T 23-10-2018 APE_1596 8e9c22a8a63a49c4f4f52e71775cba55 406 Gene3D G3DSA:3.30.300.10 27 156 2.0E-155 T 23-10-2018 APE_1596 8e9c22a8a63a49c4f4f52e71775cba55 406 Gene3D G3DSA:3.30.300.340 15 286 2.0E-155 T 23-10-2018 APE_1596 8e9c22a8a63a49c4f4f52e71775cba55 406 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 406 0.0 T 23-10-2018 APE_1596 8e9c22a8a63a49c4f4f52e71775cba55 406 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 3 401 7.0E-171 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 APE_0621.1 e5f54fc9894506d748e213904740c40b 254 Gene3D G3DSA:3.20.20.390 3 254 7.4E-83 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily APE_0621.1 e5f54fc9894506d748e213904740c40b 254 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 16 250 34.543 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 APE_0621.1 e5f54fc9894506d748e213904740c40b 254 Pfam PF01884 PcrB family 20 248 8.5E-52 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 APE_0621.1 e5f54fc9894506d748e213904740c40b 254 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 234 4.8E-70 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 APE_0621.1 e5f54fc9894506d748e213904740c40b 254 SUPERFAMILY SSF51395 21 248 3.66E-38 T 23-10-2018 APE_0621.1 e5f54fc9894506d748e213904740c40b 254 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 249 1.1E-95 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Gene3D G3DSA:3.30.365.10 191 285 5.8E-73 T 23-10-2018 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Gene3D G3DSA:3.30.365.10 149 359 5.8E-73 T 23-10-2018 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 26 134 2.1E-30 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Gene3D G3DSA:3.30.365.10 455 609 1.3E-121 T 23-10-2018 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 SUPERFAMILY SSF56003 127 760 3.53E-190 T 23-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Gene3D G3DSA:3.30.365.10 368 734 1.3E-121 T 23-10-2018 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 SMART SM01008 26 135 1.7E-48 T 23-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Gene3D G3DSA:3.90.1170.50 3 134 2.6E-45 T 23-10-2018 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 151 694 1.6E-161 T 23-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 APE_0708.1 50e8d5031db11e8e4002b5f06dd295bd 764 SUPERFAMILY SSF54665 9 156 2.49E-46 T 23-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily APE_2144.1 03b54955cbf6318eb05588afd53924de 901 Gene3D G3DSA:3.40.50.300 256 425 6.6E-27 T 23-10-2018 APE_2144.1 03b54955cbf6318eb05588afd53924de 901 SUPERFAMILY SSF52540 46 398 7.22E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2144.1 03b54955cbf6318eb05588afd53924de 901 PIRSF PIRSF037307 8 901 1.9E-302 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 APE_2144.1 03b54955cbf6318eb05588afd53924de 901 Pfam PF00271 Helicase conserved C-terminal domain 282 393 2.5E-17 T 23-10-2018 IPR001650 Helicase, C-terminal APE_2144.1 03b54955cbf6318eb05588afd53924de 901 Pfam PF08494 DEAD/H associated 654 846 8.5E-55 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 APE_2144.1 03b54955cbf6318eb05588afd53924de 901 Gene3D G3DSA:3.40.50.300 17 244 8.2E-51 T 23-10-2018 APE_2144.1 03b54955cbf6318eb05588afd53924de 901 SMART SM00490 307 397 1.3E-19 T 23-10-2018 IPR001650 Helicase, C-terminal APE_2144.1 03b54955cbf6318eb05588afd53924de 901 SMART SM00487 34 264 3.5E-34 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_2144.1 03b54955cbf6318eb05588afd53924de 901 Pfam PF00270 DEAD/DEAH box helicase 39 227 4.2E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_2308 4b7cee538afe7f2c56253179679aad1a 283 Gene3D G3DSA:3.10.270.10 1 270 3.7E-62 T 23-10-2018 APE_2308 4b7cee538afe7f2c56253179679aad1a 283 Pfam PF02649 Type I GTP cyclohydrolase folE2 2 266 5.3E-56 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 APE_2308 4b7cee538afe7f2c56253179679aad1a 283 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 270 26.984 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 APE_2308 4b7cee538afe7f2c56253179679aad1a 283 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 2 267 2.7E-34 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 PIRSF PIRSF000538 4 506 2.0E-99 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 262 1.3E-38 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 Gene3D G3DSA:3.30.420.40 264 502 3.4E-54 T 23-10-2018 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 275 455 1.0E-25 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 SUPERFAMILY SSF53067 264 501 1.57E-46 T 23-10-2018 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 367 387 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 SUPERFAMILY SSF53067 7 265 1.14E-47 T 23-10-2018 APE_0017.1 caccfeef36068cd9d3ffebd671d116cc 506 Gene3D G3DSA:3.30.420.40 4 262 1.4E-60 T 23-10-2018 APE_0772 2f8e3232663e4c8ad1cc18c8917339eb 112 Pfam PF01922 SRP19 protein 19 103 7.4E-17 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APE_0772 2f8e3232663e4c8ad1cc18c8917339eb 112 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 19 103 28.548 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type APE_0772 2f8e3232663e4c8ad1cc18c8917339eb 112 Gene3D G3DSA:3.30.56.30 16 112 1.1E-28 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APE_0772 2f8e3232663e4c8ad1cc18c8917339eb 112 SUPERFAMILY SSF69695 16 108 6.15E-25 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 Gene3D G3DSA:1.10.8.60 172 231 3.3E-15 T 23-10-2018 APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 SMART SM00382 48 170 2.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 Pfam PF03215 Rad17 cell cycle checkpoint protein 164 217 8.4E-5 T 23-10-2018 APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 Gene3D G3DSA:3.40.50.300 11 167 4.3E-39 T 23-10-2018 APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 Hamap MF_01508 Replication factor C large subunit [rfcL]. 10 446 35.029 T 23-10-2018 IPR023935 Replication factor C, large subunit APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 151 7.6E-17 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_1524.1 b925ec2ebe09c1d70b65ff92f73e2512 479 SUPERFAMILY SSF52540 10 232 2.0E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0557 2b696d79007d38b02ec40eb65a446c62 354 Gene3D G3DSA:3.30.2130.30 1 171 1.3E-24 T 23-10-2018 APE_0557 2b696d79007d38b02ec40eb65a446c62 354 SUPERFAMILY SSF53335 161 316 3.11E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0557 2b696d79007d38b02ec40eb65a446c62 354 Pfam PF01170 Putative RNA methylase family UPF0020 173 346 3.5E-55 T 23-10-2018 IPR000241 Putative RNA methylase domain APE_0557 2b696d79007d38b02ec40eb65a446c62 354 Pfam PF02926 THUMP domain 24 162 9.6E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_0557 2b696d79007d38b02ec40eb65a446c62 354 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 275 281 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APE_0557 2b696d79007d38b02ec40eb65a446c62 354 Gene3D G3DSA:3.40.50.150 172 354 1.9E-46 T 23-10-2018 APE_0557 2b696d79007d38b02ec40eb65a446c62 354 SUPERFAMILY SSF143437 12 153 7.32E-12 T 23-10-2018 APE_0557 2b696d79007d38b02ec40eb65a446c62 354 SMART SM00981 65 164 5.0E-8 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_1516.1 c7e53aff7f56e54b074b425a857ac836 212 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 77 99 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APE_1516.1 c7e53aff7f56e54b074b425a857ac836 212 Pfam PF01066 CDP-alcohol phosphatidyltransferase 36 99 7.3E-11 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APE_1516.1 c7e53aff7f56e54b074b425a857ac836 212 Gene3D G3DSA:1.20.120.1760 4 206 1.4E-44 T 23-10-2018 APE_0038.1 5ecbca23454f820b608c88455b553da3 298 Gene3D G3DSA:1.10.3720.10 43 296 1.1E-56 T 23-10-2018 IPR035906 MetI-like superfamily APE_0038.1 5ecbca23454f820b608c88455b553da3 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 283 1.2E-20 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0038.1 5ecbca23454f820b608c88455b553da3 298 SUPERFAMILY SSF161098 73 284 1.7E-46 T 23-10-2018 IPR035906 MetI-like superfamily APE_2615.1 8e797217650197625f562069dac872d0 376 Gene3D G3DSA:1.20.1250.20 202 374 5.0E-8 T 23-10-2018 APE_2615.1 8e797217650197625f562069dac872d0 376 Pfam PF07690 Major Facilitator Superfamily 36 340 1.8E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_2615.1 8e797217650197625f562069dac872d0 376 SUPERFAMILY SSF103473 25 370 1.2E-21 T 23-10-2018 IPR036259 MFS transporter superfamily APE_2615.1 8e797217650197625f562069dac872d0 376 Gene3D G3DSA:1.20.1250.20 3 194 5.2E-7 T 23-10-2018 APE_0464.1 1ee1c2ae100516b81036629a5f250027 279 SUPERFAMILY SSF51338 1 243 5.98E-12 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APE_2229.1 c5dc2064d1f02afdfe04aef0daf36836 633 Gene3D G3DSA:3.90.1600.10 293 469 2.9E-40 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2229.1 c5dc2064d1f02afdfe04aef0daf36836 633 Pfam PF00136 DNA polymerase family B 293 563 9.0E-12 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2229.1 c5dc2064d1f02afdfe04aef0daf36836 633 Gene3D G3DSA:1.10.132.60 480 567 3.9E-7 T 23-10-2018 APE_2229.1 c5dc2064d1f02afdfe04aef0daf36836 633 Gene3D G3DSA:1.10.287.690 348 395 2.9E-40 T 23-10-2018 APE_2229.1 c5dc2064d1f02afdfe04aef0daf36836 633 SUPERFAMILY SSF56672 254 626 3.39E-58 T 23-10-2018 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 10 141 20.082 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 Gene3D G3DSA:3.90.1180.10 4 152 6.3E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 PIRSF PIRSF002181 4 153 1.0E-37 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 ProSitePatterns PS00783 Ribosomal protein L13 signature. 89 112 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 11 151 3.9E-61 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 SUPERFAMILY SSF52161 11 150 6.28E-35 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 APE_1747 4276bd5ea7a47df85a28333d545c1e50 155 Pfam PF00572 Ribosomal protein L13 12 112 1.6E-10 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 APE_0472 56d847ba077a81988bc27fd05ad22679 172 Pfam PF10130 PIN domain 18 138 1.4E-26 T 23-10-2018 IPR002716 PIN domain APE_0472 56d847ba077a81988bc27fd05ad22679 172 SUPERFAMILY SSF88723 17 141 5.89E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0472 56d847ba077a81988bc27fd05ad22679 172 Gene3D G3DSA:3.40.50.1010 15 138 1.9E-8 T 23-10-2018 APE_0072 c281ae068477003d7b08827be07f8313 345 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 52 72 1.7E-10 T 23-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_0072 c281ae068477003d7b08827be07f8313 345 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 111 131 1.7E-10 T 23-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_0072 c281ae068477003d7b08827be07f8313 345 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 35 52 1.7E-10 T 23-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_0072 c281ae068477003d7b08827be07f8313 345 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 90 110 1.7E-10 T 23-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_0072 c281ae068477003d7b08827be07f8313 345 Pfam PF01578 Cytochrome C assembly protein 20 173 2.6E-19 T 23-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 APE_0257 4e2192576510e22e5b77676f34f53137 186 Gene3D G3DSA:3.30.1490.120 1 83 8.4E-14 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 APE_0257 4e2192576510e22e5b77676f34f53137 186 Pfam PF00575 S1 RNA binding domain 86 154 7.2E-9 T 23-10-2018 IPR003029 S1 domain GO:0003676 APE_0257 4e2192576510e22e5b77676f34f53137 186 SUPERFAMILY SSF88798 1 81 1.44E-10 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 APE_0257 4e2192576510e22e5b77676f34f53137 186 SMART SM00316 83 169 9.8E-6 T 23-10-2018 IPR022967 RNA-binding domain, S1 APE_0257 4e2192576510e22e5b77676f34f53137 186 SUPERFAMILY SSF50249 86 183 1.49E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0257 4e2192576510e22e5b77676f34f53137 186 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 19 80 1.3E-12 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 APE_0257 4e2192576510e22e5b77676f34f53137 186 Gene3D G3DSA:2.40.50.140 86 186 8.7E-17 T 23-10-2018 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 381 5.7E-45 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 Gene3D G3DSA:1.10.540.10 11 125 8.9E-36 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 PIRSF PIRSF016578 9 114 1.4E-6 T 23-10-2018 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 PIRSF PIRSF016578 136 386 1.7E-16 T 23-10-2018 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 Gene3D G3DSA:2.40.110.10 126 239 7.7E-36 T 23-10-2018 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 123 1.2E-32 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 Gene3D G3DSA:1.20.140.10 240 387 1.1E-48 T 23-10-2018 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 23-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.4E-23 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 SUPERFAMILY SSF47203 232 388 6.93E-52 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_1681.1 e7ef14156e9e6e1be8791e58bc00dc5e 389 SUPERFAMILY SSF56645 12 247 1.05E-71 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APE_1440 f34626dc4c12f752210f3904a68819e5 123 Pfam PF01920 Prefoldin subunit 11 114 7.6E-25 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 APE_1440 f34626dc4c12f752210f3904a68819e5 123 Gene3D G3DSA:1.10.287.370 2 118 6.4E-30 T 23-10-2018 IPR009053 Prefoldin APE_1440 f34626dc4c12f752210f3904a68819e5 123 SUPERFAMILY SSF46579 8 113 2.49E-22 T 23-10-2018 APE_1440 f34626dc4c12f752210f3904a68819e5 123 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 123 33.792 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 APE_1440 f34626dc4c12f752210f3904a68819e5 123 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 5 113 1.0E-23 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 PIRSF PIRSF000726 6 451 2.8E-65 T 23-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 7 448 3.9E-115 T 23-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 Gene3D G3DSA:3.40.1160.10 8 296 9.7E-69 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 7 450 2.4E-142 T 23-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 Pfam PF00696 Amino acid kinase family 8 282 8.1E-43 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 SUPERFAMILY SSF55021 305 376 9.67E-13 T 23-10-2018 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 SUPERFAMILY SSF53633 9 288 2.23E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 Gene3D G3DSA:3.30.2130.10 302 450 7.9E-15 T 23-10-2018 APE_1140.1 5bcdd6779d17e3a5b661a126038c6de6 454 Pfam PF01842 ACT domain 322 374 1.7E-7 T 23-10-2018 IPR002912 ACT domain APE_0433 24ec54affd5bc5a1252ec03b409d3044 174 Hamap MF_01117 CDP-archaeol synthase [carS]. 21 174 26.262 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 APE_0433 24ec54affd5bc5a1252ec03b409d3044 174 Pfam PF01864 CDP-archaeol synthase 12 174 1.0E-41 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 SUPERFAMILY SSF56235 22 210 2.04E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 Hamap MF_02113_A Proteasome subunit beta [prcB]. 21 216 36.201 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 25 207 2.2E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 PRINTS PR00141 Proteasome component signature 153 164 1.3E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 PRINTS PR00141 Proteasome component signature 189 200 1.3E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 PRINTS PR00141 Proteasome component signature 33 48 1.3E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 PRINTS PR00141 Proteasome component signature 164 175 1.3E-10 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 Pfam PF00227 Proteasome subunit 22 203 1.8E-55 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0521.1 ea9595793d5d62cad91bd49f2e84faad 219 Gene3D G3DSA:3.60.20.10 13 213 3.2E-65 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 SUPERFAMILY SSF102114 10 350 2.09E-57 T 23-10-2018 APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 Pfam PF04055 Radical SAM superfamily 18 176 2.6E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 PIRSF PIRSF037420 4 385 1.2E-87 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 Pfam PF13186 Iron-sulfur cluster-binding domain 289 343 2.3E-4 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 Pfam PF13353 4Fe-4S single cluster domain 16 84 4.0E-5 T 23-10-2018 APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 Gene3D G3DSA:3.20.20.70 7 231 4.6E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 SMART SM00729 12 216 1.8E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_1655 2d616f20c74efaadd0ce064ad1c34fc8 403 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 6 373 2.3E-156 T 23-10-2018 IPR027634 Radical SAM protein, BA_1875 family APE_1773.1 935a2f6d4fa34d44c2f0e95805586aa6 442 Pfam PF01554 MatE 236 397 2.4E-22 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_1773.1 935a2f6d4fa34d44c2f0e95805586aa6 442 Pfam PF01554 MatE 18 176 4.0E-21 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_1773.1 935a2f6d4fa34d44c2f0e95805586aa6 442 TIGRFAM TIGR00797 matE: MATE efflux family protein 18 403 2.4E-69 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_1773.1 935a2f6d4fa34d44c2f0e95805586aa6 442 PIRSF PIRSF006603 2 441 1.8E-69 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 APE_0184.1 65dd78de3ef7dde13ce1cd0c648ac165 418 Gene3D G3DSA:1.20.1250.20 9 392 5.0E-39 T 23-10-2018 APE_0184.1 65dd78de3ef7dde13ce1cd0c648ac165 418 SUPERFAMILY SSF103473 11 393 1.44E-45 T 23-10-2018 IPR036259 MFS transporter superfamily APE_0184.1 65dd78de3ef7dde13ce1cd0c648ac165 418 Pfam PF07690 Major Facilitator Superfamily 12 227 7.2E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 Gene3D G3DSA:3.40.50.720 188 347 1.5E-178 T 23-10-2018 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 SMART SM00996 4 416 9.8E-163 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 412 2.9E-27 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 PIRSF PIRSF001109 1 416 4.9E-197 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 SMART SM00997 186 347 4.3E-111 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 416 48.962 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 SUPERFAMILY SSF51735 186 348 3.3E-69 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 5 139 2.7E-42 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 Gene3D G3DSA:3.40.50.1480 7 408 1.5E-178 T 23-10-2018 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 SUPERFAMILY SSF52283 3 416 3.34E-97 T 23-10-2018 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 186 346 1.2E-58 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 208 225 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 76 90 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0624.1 530499e27d50c7176bfb9953f55d8e65 416 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 5 416 6.5E-210 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 APE_0671 7fafa314f79140b58317473cc76b7e1a 383 Pfam PF07690 Major Facilitator Superfamily 20 259 1.7E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_0671 7fafa314f79140b58317473cc76b7e1a 383 SUPERFAMILY SSF103473 8 379 2.88E-40 T 23-10-2018 IPR036259 MFS transporter superfamily APE_0671 7fafa314f79140b58317473cc76b7e1a 383 Gene3D G3DSA:1.20.1250.20 195 381 1.5E-10 T 23-10-2018 APE_0671 7fafa314f79140b58317473cc76b7e1a 383 Gene3D G3DSA:1.20.1250.20 7 187 1.8E-17 T 23-10-2018 APE_1950.1 8bba9b28988fedbde6ba662326470eab 176 Pfam PF00011 Hsp20/alpha crystallin family 92 172 5.1E-9 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain APE_1950.1 8bba9b28988fedbde6ba662326470eab 176 Gene3D G3DSA:2.60.40.790 81 165 4.4E-21 T 23-10-2018 IPR008978 HSP20-like chaperone APE_1950.1 8bba9b28988fedbde6ba662326470eab 176 SUPERFAMILY SSF49764 83 168 6.93E-21 T 23-10-2018 IPR008978 HSP20-like chaperone APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 Pfam PF04851 Type III restriction enzyme, res subunit 31 191 1.7E-11 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 SUPERFAMILY SSF52540 78 568 7.23E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 Pfam PF13020 Domain of unknown function (DUF3883) 917 1004 5.5E-17 T 23-10-2018 IPR024975 Domain of unknown function DUF3883 APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 SUPERFAMILY SSF51182 346 486 1.69E-6 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 Gene3D G3DSA:3.40.50.10810 27 288 6.0E-38 T 23-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 Pfam PF00271 Helicase conserved C-terminal domain 451 553 2.5E-13 T 23-10-2018 IPR001650 Helicase, C-terminal APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 Gene3D G3DSA:3.40.50.300 380 582 1.2E-32 T 23-10-2018 APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 SMART SM00490 470 553 9.6E-15 T 23-10-2018 IPR001650 Helicase, C-terminal APE_0413 5829abaae017110e9a2f8d4419b41dac 1039 SMART SM00487 25 227 7.0E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_2213 fb64775e4fcf2004587617785aa7a487 163 SUPERFAMILY SSF54292 10 86 1.44E-25 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 APE_2213 fb64775e4fcf2004587617785aa7a487 163 Gene3D G3DSA:3.10.20.30 3 82 3.6E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily APE_2213 fb64775e4fcf2004587617785aa7a487 163 Pfam PF01799 [2Fe-2S] binding domain 81 152 5.7E-31 T 23-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 APE_2213 fb64775e4fcf2004587617785aa7a487 163 Gene3D G3DSA:1.10.150.120 83 163 9.7E-34 T 23-10-2018 APE_2213 fb64775e4fcf2004587617785aa7a487 163 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 67 2.9E-6 T 23-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 APE_2213 fb64775e4fcf2004587617785aa7a487 163 SUPERFAMILY SSF47741 92 161 1.02E-32 T 23-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily APE_1727.1 d9273839b2ca445ca3e110921c3371b0 147 Pfam PF07884 Vitamin K epoxide reductase family 12 138 3.5E-14 T 23-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 APE_1727.1 d9273839b2ca445ca3e110921c3371b0 147 Gene3D G3DSA:1.20.1440.130 6 145 4.9E-6 T 23-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 APE_1727.1 d9273839b2ca445ca3e110921c3371b0 147 SMART SM00756 4 144 4.4E-30 T 23-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 APE_0546.1 f556aade95a32ccfb6fd5f304a36b084 437 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 10 430 58.946 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 APE_0546.1 f556aade95a32ccfb6fd5f304a36b084 437 SUPERFAMILY SSF55120 315 429 6.91E-12 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APE_0546.1 f556aade95a32ccfb6fd5f304a36b084 437 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 10 431 5.5E-166 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 APE_0546.1 f556aade95a32ccfb6fd5f304a36b084 437 Gene3D G3DSA:3.30.70.2510 199 317 9.4E-21 T 23-10-2018 APE_0546.1 f556aade95a32ccfb6fd5f304a36b084 437 Gene3D G3DSA:3.30.70.3190 319 429 4.2E-27 T 23-10-2018 APE_0546.1 f556aade95a32ccfb6fd5f304a36b084 437 Pfam PF02926 THUMP domain 24 198 4.9E-30 T 23-10-2018 IPR004114 THUMP domain GO:0003723 APE_2219 7fe4b843fa72d1be135555e63b4059af 292 SUPERFAMILY SSF55447 180 285 1.26E-29 T 23-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily APE_2219 7fe4b843fa72d1be135555e63b4059af 292 SUPERFAMILY SSF56176 4 173 1.85E-57 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APE_2219 7fe4b843fa72d1be135555e63b4059af 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 1.9E-55 T 23-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 APE_2219 7fe4b843fa72d1be135555e63b4059af 292 Gene3D G3DSA:3.30.390.50 179 291 1.2E-35 T 23-10-2018 APE_2219 7fe4b843fa72d1be135555e63b4059af 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 282 2.1E-26 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal APE_2219 7fe4b843fa72d1be135555e63b4059af 292 Gene3D G3DSA:3.30.43.10 1 54 9.7E-21 T 23-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 APE_2219 7fe4b843fa72d1be135555e63b4059af 292 Gene3D G3DSA:3.30.465.10 59 174 7.4E-44 T 23-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 APE_2219 7fe4b843fa72d1be135555e63b4059af 292 SMART SM01092 181 283 4.7E-34 T 23-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal APE_0270.1 911ace0d6a76f5a95ed5da723b0fd07f 261 Gene3D G3DSA:1.10.3720.10 4 259 4.3E-44 T 23-10-2018 IPR035906 MetI-like superfamily APE_0270.1 911ace0d6a76f5a95ed5da723b0fd07f 261 SUPERFAMILY SSF161098 23 248 3.92E-43 T 23-10-2018 IPR035906 MetI-like superfamily APE_0270.1 911ace0d6a76f5a95ed5da723b0fd07f 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 256 7.6E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1158.1 342139a98a539bd8318f0cbc262f2c38 522 SMART SM00729 192 407 1.2E-30 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_1158.1 342139a98a539bd8318f0cbc262f2c38 522 Gene3D G3DSA:3.80.30.20 193 416 3.0E-11 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APE_1158.1 342139a98a539bd8318f0cbc262f2c38 522 Pfam PF04055 Radical SAM superfamily 197 357 7.8E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1158.1 342139a98a539bd8318f0cbc262f2c38 522 SUPERFAMILY SSF102114 184 446 2.62E-27 T 23-10-2018 APE_0553 6f236067c27304be5130804a30f56b3a 277 SUPERFAMILY SSF53335 26 275 1.62E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0553 6f236067c27304be5130804a30f56b3a 277 SMART SM00650 42 209 3.1E-51 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 APE_0553 6f236067c27304be5130804a30f56b3a 277 Pfam PF00398 Ribosomal RNA adenine dimethylase 31 241 1.5E-26 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm APE_0553 6f236067c27304be5130804a30f56b3a 277 Gene3D G3DSA:3.40.50.150 12 210 3.8E-41 T 23-10-2018 APE_0553 6f236067c27304be5130804a30f56b3a 277 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 27 274 8.3E-65 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 APE_1138.1 0dbac427f9007599c0b0d5cff41a698e 188 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 5 182 7.8E-52 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 APE_1138.1 0dbac427f9007599c0b0d5cff41a698e 188 SUPERFAMILY SSF52972 4 183 7.06E-56 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APE_1138.1 0dbac427f9007599c0b0d5cff41a698e 188 Pfam PF01725 Ham1 family 5 181 1.3E-46 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 APE_1138.1 0dbac427f9007599c0b0d5cff41a698e 188 Gene3D G3DSA:3.90.950.10 4 186 1.4E-61 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APE_1138.1 0dbac427f9007599c0b0d5cff41a698e 188 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 184 38.043 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 APE_2464.1 c43c0ce93c4aac5f298666e9c819942b 387 Gene3D G3DSA:3.40.50.300 11 217 4.6E-34 T 23-10-2018 APE_2464.1 c43c0ce93c4aac5f298666e9c819942b 387 SUPERFAMILY SSF52540 15 170 3.32E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2464.1 c43c0ce93c4aac5f298666e9c819942b 387 Gene3D G3DSA:3.30.300.20 251 307 1.3E-6 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta APE_2464.1 c43c0ce93c4aac5f298666e9c819942b 387 Pfam PF02562 PhoH-like protein 14 216 7.3E-47 T 23-10-2018 IPR003714 PhoH-like protein GO:0005524 APE_2464.1 c43c0ce93c4aac5f298666e9c819942b 387 Pfam PF07650 KH domain 257 308 5.5E-8 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0093.1 fdc5764c85c56cbd45dba59e8ae36dca 345 SUPERFAMILY SSF89447 23 64 5.93E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily APE_0093.1 fdc5764c85c56cbd45dba59e8ae36dca 345 SMART SM00966 19 64 3.7E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0093.1 fdc5764c85c56cbd45dba59e8ae36dca 345 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 23 58 4.6E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_1791.1 af63da715994596f24d42809c850957a 465 SUPERFAMILY SSF81301 9 203 1.0E-24 T 23-10-2018 APE_1791.1 af63da715994596f24d42809c850957a 465 SUPERFAMILY SSF55003 268 403 1.26E-17 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 APE_1791.1 af63da715994596f24d42809c850957a 465 Hamap MF_01264 CCA-adding enzyme [cca]. 1 465 89.387 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 APE_1791.1 af63da715994596f24d42809c850957a 465 Gene3D G3DSA:3.30.460.10 24 159 1.3E-65 T 23-10-2018 APE_1791.1 af63da715994596f24d42809c850957a 465 Gene3D G3DSA:1.10.1410.30 17 281 1.3E-65 T 23-10-2018 APE_1791.1 af63da715994596f24d42809c850957a 465 SUPERFAMILY SSF81631 163 282 2.75E-34 T 23-10-2018 APE_1791.1 af63da715994596f24d42809c850957a 465 Pfam PF09249 tRNA nucleotidyltransferase, second domain 165 281 1.4E-38 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 APE_1791.1 af63da715994596f24d42809c850957a 465 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 16 415 7.1E-110 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 APE_1791.1 af63da715994596f24d42809c850957a 465 Pfam PF01909 Nucleotidyltransferase domain 40 163 4.5E-19 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 APE_1791.1 af63da715994596f24d42809c850957a 465 PIRSF PIRSF005335 12 464 7.7E-127 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 APE_0996.1 b3432c7fbdf994c471c26e4fad06399e 448 Gene3D G3DSA:3.40.50.10180 45 267 3.4E-131 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 APE_0996.1 b3432c7fbdf994c471c26e4fad06399e 448 SUPERFAMILY SSF82544 14 437 4.32E-125 T 23-10-2018 APE_0996.1 b3432c7fbdf994c471c26e4fad06399e 448 Pfam PF13660 Domain of unknown function (DUF4147) 17 240 5.4E-71 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 APE_0996.1 b3432c7fbdf994c471c26e4fad06399e 448 Pfam PF05161 MOFRL family 324 430 2.1E-30 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 APE_0996.1 b3432c7fbdf994c471c26e4fad06399e 448 Gene3D G3DSA:3.40.1480.10 268 434 3.4E-131 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily APE_0476.1 a0d587f17ce971ea6f6b861c538740a2 185 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 65 176 4.0E-5 T 23-10-2018 IPR002802 Protein of unknown function DUF99 APE_0476.1 a0d587f17ce971ea6f6b861c538740a2 185 Pfam PF01949 Protein of unknown function DUF99 1 178 1.4E-39 T 23-10-2018 IPR002802 Protein of unknown function DUF99 APE_0476.1 a0d587f17ce971ea6f6b861c538740a2 185 PIRSF PIRSF006380 1 185 1.7E-53 T 23-10-2018 IPR002802 Protein of unknown function DUF99 APE_0476.1 a0d587f17ce971ea6f6b861c538740a2 185 Gene3D G3DSA:3.30.2170.10 2 183 5.6E-31 T 23-10-2018 APE_0476.1 a0d587f17ce971ea6f6b861c538740a2 185 Hamap MF_00582 UPF0215 protein . 8 180 24.799 T 23-10-2018 IPR002802 Protein of unknown function DUF99 APE_2423 5fa51a8485ef28a74afddbfffd055f9b 382 Gene3D G3DSA:3.90.1150.10 9 370 6.2E-132 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2423 5fa51a8485ef28a74afddbfffd055f9b 382 Gene3D G3DSA:3.40.640.10 14 257 6.2E-132 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2423 5fa51a8485ef28a74afddbfffd055f9b 382 SUPERFAMILY SSF53383 3 361 1.46E-99 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2423 5fa51a8485ef28a74afddbfffd055f9b 382 Pfam PF00266 Aminotransferase class-V 4 323 2.5E-33 T 23-10-2018 IPR000192 Aminotransferase class V domain APE_2423 5fa51a8485ef28a74afddbfffd055f9b 382 PIRSF PIRSF000524 1 381 1.5E-142 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 APE_2423 5fa51a8485ef28a74afddbfffd055f9b 382 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 180 200 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 Gene3D G3DSA:3.30.70.80 28 94 7.5E-8 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 184 194 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 145 156 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 Pfam PF00082 Subtilase family 143 416 7.3E-45 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 SUPERFAMILY SSF52743 109 427 1.83E-86 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 Gene3D G3DSA:3.40.50.200 106 429 8.6E-101 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 353 363 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 PRINTS PR00723 Subtilisin serine protease family (S8) signature 140 159 5.9E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 PRINTS PR00723 Subtilisin serine protease family (S8) signature 352 368 5.9E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_0263.1 a6988bc8c0ca0ba0f6fbccc26f28ed8c 430 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 193 5.9E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_0147.1 d92b31b972b3fae9c7766b07dd989257 183 Pfam PF07998 Peptidase family M54 46 174 6.5E-32 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 APE_0147.1 d92b31b972b3fae9c7766b07dd989257 183 Gene3D G3DSA:3.40.390.10 18 179 7.3E-45 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 APE_0147.1 d92b31b972b3fae9c7766b07dd989257 183 Hamap MF_01842 Archaemetzincin [amzA]. 5 175 34.43 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 APE_0147.1 d92b31b972b3fae9c7766b07dd989257 183 SUPERFAMILY SSF55486 80 170 3.8E-13 T 23-10-2018 APE_2349.1 d490f202a76c675f9604c188c098caa4 186 Pfam PF00156 Phosphoribosyl transferase domain 69 158 2.2E-16 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APE_2349.1 d490f202a76c675f9604c188c098caa4 186 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 186 22.661 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_2349.1 d490f202a76c675f9604c188c098caa4 186 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 177 3.8E-38 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_2349.1 d490f202a76c675f9604c188c098caa4 186 SUPERFAMILY SSF53271 6 181 1.13E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_2349.1 d490f202a76c675f9604c188c098caa4 186 Gene3D G3DSA:3.40.50.2020 9 186 1.8E-54 T 23-10-2018 APE_1199 7177b94f80eb595902d51805659778f8 458 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 4 405 1.7E-59 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 APE_1199 7177b94f80eb595902d51805659778f8 458 Gene3D G3DSA:3.40.720.10 1 278 5.6E-36 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APE_1199 7177b94f80eb595902d51805659778f8 458 SUPERFAMILY SSF53649 2 340 3.6E-28 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 APE_2359.1 552e347d82aff2f8b3b7b988498e6652 185 SMART SM00471 28 142 1.7E-9 T 23-10-2018 IPR003607 HD/PDEase domain APE_2359.1 552e347d82aff2f8b3b7b988498e6652 185 Gene3D G3DSA:1.10.3210.10 3 171 3.7E-29 T 23-10-2018 APE_2359.1 552e347d82aff2f8b3b7b988498e6652 185 SUPERFAMILY SSF109604 8 154 3.05E-23 T 23-10-2018 APE_2359.1 552e347d82aff2f8b3b7b988498e6652 185 Pfam PF13023 HD domain 11 130 1.0E-13 T 23-10-2018 IPR006674 HD domain APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 1.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 1.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 1.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 1.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 1.3E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 122 3.0E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 9.3E-33 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 8.1E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 8.1E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 8.1E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 8.1E-23 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 34.91 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 Gene3D G3DSA:3.30.1330.30 4 127 1.1E-44 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 APE_1818 77e3c86b4f4586e85e04029ebc16d729 127 SUPERFAMILY SSF55315 4 121 1.73E-41 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1627 68e02ab97042b7d3af94390393baa99c 233 Gene3D G3DSA:3.40.630.30 15 186 4.5E-56 T 23-10-2018 APE_1627 68e02ab97042b7d3af94390393baa99c 233 PIRSF PIRSF017998 19 231 2.9E-91 T 23-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 APE_1627 68e02ab97042b7d3af94390393baa99c 233 SUPERFAMILY SSF55729 17 226 1.06E-58 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_1627 68e02ab97042b7d3af94390393baa99c 233 Pfam PF06557 Protein of unknown function (DUF1122) 38 210 1.9E-68 T 23-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 APE_0710.1 57a251107d2124276c21aff98800f19a 288 Pfam PF09171 N-glycosylase/DNA lyase 15 259 3.0E-68 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 APE_0710.1 57a251107d2124276c21aff98800f19a 288 Hamap MF_01168 N-glycosylase/DNA lyase. 12 265 32.216 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 APE_0710.1 57a251107d2124276c21aff98800f19a 288 Gene3D G3DSA:1.10.340.30 33 181 2.8E-40 T 23-10-2018 APE_0710.1 57a251107d2124276c21aff98800f19a 288 SUPERFAMILY SSF48150 7 252 1.26E-60 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APE_0710.1 57a251107d2124276c21aff98800f19a 288 PIRSF PIRSF008955 4 271 8.2E-91 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 APE_0710.1 57a251107d2124276c21aff98800f19a 288 Gene3D G3DSA:1.10.1670.10 18 245 2.8E-40 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 Gene3D G3DSA:1.10.246.90 259 383 9.0E-50 T 23-10-2018 APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 SMART SM00931 145 197 1.1E-25 T 23-10-2018 IPR012976 NOSIC APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 Pfam PF01798 snoRNA binding domain, fibrillarin 153 378 2.0E-73 T 23-10-2018 IPR002687 Nop domain APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 Gene3D G3DSA:3.30.420.220 5 140 2.5E-31 T 23-10-2018 APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 SUPERFAMILY SSF89124 140 380 6.28E-80 T 23-10-2018 IPR036070 Nop domain superfamily APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 Gene3D G3DSA:1.10.287.660 147 258 1.5E-38 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily APE_2199.1 31738b20c5ca778998e9edafb4e4439d 419 Gene3D G3DSA:1.10.150.460 176 227 1.5E-38 T 23-10-2018 APE_0782.1 69ebf64be5c1cea3f4dfcfd7ed50a405 407 Gene3D G3DSA:3.30.56.70 345 402 1.4E-14 T 23-10-2018 APE_0782.1 69ebf64be5c1cea3f4dfcfd7ed50a405 407 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 10 402 40.006 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 APE_0782.1 69ebf64be5c1cea3f4dfcfd7ed50a405 407 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 39 399 1.5E-80 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 APE_0782.1 69ebf64be5c1cea3f4dfcfd7ed50a405 407 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 16 402 3.2E-85 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 APE_0782.1 69ebf64be5c1cea3f4dfcfd7ed50a405 407 Gene3D G3DSA:3.40.50.150 7 339 1.3E-74 T 23-10-2018 APE_0782.1 69ebf64be5c1cea3f4dfcfd7ed50a405 407 SUPERFAMILY SSF53335 13 399 4.25E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 Pfam PF03104 DNA polymerase family B, exonuclease domain 35 317 9.1E-33 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 Gene3D G3DSA:3.30.420.10 182 388 1.8E-45 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 SMART SM00486 182 591 1.9E-117 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 Gene3D G3DSA:1.10.287.690 489 541 1.6E-18 T 23-10-2018 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 Pfam PF00136 DNA polymerase family B 377 777 2.4E-69 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 SUPERFAMILY SSF56672 392 782 6.12E-115 T 23-10-2018 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 Gene3D G3DSA:3.30.342.10 12 155 9.1E-32 T 23-10-2018 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 ProSitePatterns PS00116 DNA polymerase family B signature. 579 587 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 Gene3D G3DSA:1.10.132.60 640 803 1.8E-47 T 23-10-2018 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 228 776 5.0E-82 T 23-10-2018 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 525 537 1.5E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 577 585 1.5E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 437 450 1.5E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_2098.1 b44c94487df619c2a916b6ac8d163f91 803 SUPERFAMILY SSF53098 14 387 1.14E-72 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily APE_1796.1 872f50ff278cf4853b0fd002a8a9a5e3 147 Gene3D G3DSA:2.10.109.10 28 79 1.4E-6 T 23-10-2018 APE_1796.1 872f50ff278cf4853b0fd002a8a9a5e3 147 SUPERFAMILY SSF51306 19 71 4.45E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily APE_1796.1 872f50ff278cf4853b0fd002a8a9a5e3 147 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 81 92 2.3E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 APE_1796.1 872f50ff278cf4853b0fd002a8a9a5e3 147 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 26 41 2.3E-6 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 APE_1796.1 872f50ff278cf4853b0fd002a8a9a5e3 147 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 4 142 2.8E-20 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 APE_1796.1 872f50ff278cf4853b0fd002a8a9a5e3 147 Pfam PF00717 Peptidase S24-like 26 70 1.1E-8 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C APE_0258.1 21da1ebe761ea7f8b345d895a45936ee 310 Pfam PF02589 LUD domain 68 298 1.2E-54 T 23-10-2018 IPR003741 LUD domain APE_0258.1 21da1ebe761ea7f8b345d895a45936ee 310 Gene3D G3DSA:3.40.50.10420 118 298 2.4E-33 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily APE_0258.1 21da1ebe761ea7f8b345d895a45936ee 310 SUPERFAMILY SSF100950 63 299 1.38E-45 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Gene3D G3DSA:2.40.340.10 340 404 2.0E-67 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 SUPERFAMILY SSF63867 351 411 7.19E-7 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 SMART SM00852 195 330 4.5E-17 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Gene3D G3DSA:3.40.980.10 190 339 2.0E-67 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 SUPERFAMILY SSF63882 12 188 3.79E-29 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 SUPERFAMILY SSF53218 192 330 2.36E-24 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Gene3D G3DSA:3.90.105.10 39 189 2.0E-67 T 23-10-2018 APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 182 8.6E-25 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Pfam PF00994 Probable molybdopterin binding domain 196 329 7.6E-9 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Gene3D G3DSA:2.170.190.11 63 156 2.0E-67 T 23-10-2018 APE_0450 7675c2e33e20b0f0a0bc3985ae5e1f95 577 Pfam PF03454 MoeA C-terminal region (domain IV) 344 409 5.4E-12 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_1221 2a2d5a506c52f653829874bc7ef0adf0 356 SUPERFAMILY SSF57997 51 244 1.9E-17 T 23-10-2018 APE_1221 2a2d5a506c52f653829874bc7ef0adf0 356 Pfam PF07788 PD-(D/E)XK nuclease superfamily 281 349 7.4E-26 T 23-10-2018 IPR012431 PD-(D/E)XK nuclease APE_1221 2a2d5a506c52f653829874bc7ef0adf0 356 Gene3D G3DSA:1.20.5.340 110 201 5.3E-8 T 23-10-2018 APE_1221 2a2d5a506c52f653829874bc7ef0adf0 356 Pfam PF12644 Protein of unknown function (DUF3782) 202 280 2.3E-22 T 23-10-2018 IPR024271 Protein of unknown function DUF3782 APE_1317 5048a1acf65e0156cf272465eba03c18 306 PIRSF PIRSF002849 1 306 4.9E-127 T 23-10-2018 APE_1317 5048a1acf65e0156cf272465eba03c18 306 SMART SM00382 32 173 1.1E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1317 5048a1acf65e0156cf272465eba03c18 306 Gene3D G3DSA:1.10.8.300 200 303 6.3E-28 T 23-10-2018 APE_1317 5048a1acf65e0156cf272465eba03c18 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 35 164 8.4E-64 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 APE_1317 5048a1acf65e0156cf272465eba03c18 306 Gene3D G3DSA:3.40.50.300 1 199 1.6E-51 T 23-10-2018 APE_1317 5048a1acf65e0156cf272465eba03c18 306 SUPERFAMILY SSF52540 6 278 4.0E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 SUPERFAMILY SSF52016 376 552 1.41E-56 T 23-10-2018 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 SUPERFAMILY SSF143975 3 373 9.15E-125 T 23-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 Pfam PF00920 Dehydratase family 34 550 2.3E-197 T 23-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 462 473 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 23-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 Gene3D G3DSA:3.50.30.80 376 525 6.8E-51 T 23-10-2018 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 553 43.103 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APE_0013.1 ba9557781b723f7e83fbbb687ced91ec 553 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 17 552 4.5E-202 T 23-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 APE_1730.1 129679b30e84d5dee24605df0c89a252 594 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 404 572 1.2E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1730.1 129679b30e84d5dee24605df0c89a252 594 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 291 1.1E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1730.1 129679b30e84d5dee24605df0c89a252 594 Gene3D G3DSA:1.10.3720.10 319 589 2.3E-42 T 23-10-2018 IPR035906 MetI-like superfamily APE_1730.1 129679b30e84d5dee24605df0c89a252 594 SUPERFAMILY SSF161098 10 282 2.99E-33 T 23-10-2018 IPR035906 MetI-like superfamily APE_1730.1 129679b30e84d5dee24605df0c89a252 594 SUPERFAMILY SSF161098 318 586 1.74E-41 T 23-10-2018 IPR035906 MetI-like superfamily APE_1730.1 129679b30e84d5dee24605df0c89a252 594 Gene3D G3DSA:1.10.3720.10 70 297 1.7E-42 T 23-10-2018 IPR035906 MetI-like superfamily APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Gene3D G3DSA:2.40.30.10 208 323 1.7E-41 T 23-10-2018 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Gene3D G3DSA:3.40.50.300 4 207 3.5E-56 T 23-10-2018 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 329 413 3.9E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 3 414 62.286 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 SUPERFAMILY SSF50447 207 321 7.07E-36 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 7 414 3.7E-205 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 PRINTS PR00315 GTP-binding elongation factor signature 90 100 1.0E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.0E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 PRINTS PR00315 GTP-binding elongation factor signature 144 153 1.0E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 PRINTS PR00315 GTP-binding elongation factor signature 106 117 1.0E-13 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Gene3D G3DSA:2.40.30.10 325 414 1.4E-30 T 23-10-2018 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Pfam PF00009 Elongation factor Tu GTP binding domain 11 203 2.6E-29 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 SUPERFAMILY SSF50465 322 414 5.28E-31 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 SUPERFAMILY SSF52540 6 205 1.43E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 199 1.3E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APE_2366.1 6376fabce4081fd359478dcccd1e7a17 414 Pfam PF03144 Elongation factor Tu domain 2 235 307 8.4E-8 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APE_1003.1 547645173d96e6a5541daad2dfb3ecaf 530 SUPERFAMILY SSF53187 180 385 1.41E-23 T 23-10-2018 APE_1003.1 547645173d96e6a5541daad2dfb3ecaf 530 Gene3D G3DSA:3.50.30.30 66 192 4.9E-26 T 23-10-2018 APE_1003.1 547645173d96e6a5541daad2dfb3ecaf 530 Gene3D G3DSA:3.40.630.10 35 370 4.9E-26 T 23-10-2018 APE_1003.1 547645173d96e6a5541daad2dfb3ecaf 530 Pfam PF04389 Peptidase family M28 209 382 1.8E-12 T 23-10-2018 IPR007484 Peptidase M28 APE_1488.1 9b6fe4d868c044c2fe5db35e7919d330 340 Gene3D G3DSA:3.40.50.1100 73 166 1.0E-59 T 23-10-2018 APE_1488.1 9b6fe4d868c044c2fe5db35e7919d330 340 SUPERFAMILY SSF53686 7 335 1.7E-58 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_1488.1 9b6fe4d868c044c2fe5db35e7919d330 340 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 65 78 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 APE_1488.1 9b6fe4d868c044c2fe5db35e7919d330 340 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 47 323 2.3E-54 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_1488.1 9b6fe4d868c044c2fe5db35e7919d330 340 Gene3D G3DSA:3.40.50.1100 46 328 1.0E-59 T 23-10-2018 APE_0276.1 effa21902d62891d240f6ff61de11fcf 172 Pfam PF11848 Domain of unknown function (DUF3368) 121 165 1.1E-16 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 APE_0276.1 effa21902d62891d240f6ff61de11fcf 172 SUPERFAMILY SSF88723 27 127 6.67E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0173.1 744c369239ad4746147a8ca821a2a275 415 SUPERFAMILY SSF53748 10 405 1.08E-99 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PIRSF PIRSF000724 6 413 7.8E-117 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 12 407 32.404 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 Gene3D G3DSA:3.40.50.1260 17 404 4.8E-104 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 325 350 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 115 130 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 150 172 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 17 33 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 383 400 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 39 61 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 203 222 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 PRINTS PR00477 Phosphoglycerate kinase family signature 180 202 2.2E-51 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 Pfam PF00162 Phosphoglycerate kinase 13 396 1.8E-92 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 22 32 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_0173.1 744c369239ad4746147a8ca821a2a275 415 Gene3D G3DSA:3.40.50.1260 199 397 4.8E-104 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_2500.1 0de71e0e11a175af917b27f93c1afd6b 1180 Gene3D G3DSA:1.20.1640.10 645 826 3.7E-7 T 23-10-2018 APE_2500.1 0de71e0e11a175af917b27f93c1afd6b 1180 Pfam PF03176 MMPL family 612 830 5.8E-28 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 APE_2500.1 0de71e0e11a175af917b27f93c1afd6b 1180 Pfam PF03176 MMPL family 944 1164 3.8E-25 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 APE_2500.1 0de71e0e11a175af917b27f93c1afd6b 1180 SUPERFAMILY SSF82866 961 1164 8.11E-19 T 23-10-2018 APE_2500.1 0de71e0e11a175af917b27f93c1afd6b 1180 SUPERFAMILY SSF82866 626 824 5.1E-22 T 23-10-2018 APE_2466 61e817b8d915724063de2c72f7ce286a 395 Pfam PF07690 Major Facilitator Superfamily 8 337 5.2E-23 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_2466 61e817b8d915724063de2c72f7ce286a 395 SUPERFAMILY SSF103473 3 369 1.96E-42 T 23-10-2018 IPR036259 MFS transporter superfamily APE_2466 61e817b8d915724063de2c72f7ce286a 395 Gene3D G3DSA:1.20.1250.20 1 175 5.7E-16 T 23-10-2018 APE_2466 61e817b8d915724063de2c72f7ce286a 395 Gene3D G3DSA:1.20.1250.20 199 379 1.4E-21 T 23-10-2018 APE_0067a e878988103056722b0803932c5f908a5 153 SUPERFAMILY SSF53146 1 137 2.35E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily APE_0067a e878988103056722b0803932c5f908a5 153 Gene3D G3DSA:3.30.420.130 1 140 1.8E-12 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily APE_0067a e878988103056722b0803932c5f908a5 153 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 20 125 2.5E-6 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis APE_0461 709598d2189733468ad4b9d52887cb88 143 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 10 102 2.3E-31 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc APE_0461 709598d2189733468ad4b9d52887cb88 143 Gene3D G3DSA:3.40.1350.10 2 141 1.5E-43 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APE_0461 709598d2189733468ad4b9d52887cb88 143 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 11 98 8.0E-34 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal APE_0461 709598d2189733468ad4b9d52887cb88 143 SUPERFAMILY SSF52980 10 135 1.47E-24 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 APE_0461 709598d2189733468ad4b9d52887cb88 143 PIRSF PIRSF004985 1 141 6.7E-42 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal APE_0461 709598d2189733468ad4b9d52887cb88 143 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 3 137 37.617 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal APE_2289.1 f7ad625f6323b5311e8235c8263d031f 162 SUPERFAMILY SSF103165 3 161 1.83E-70 T 23-10-2018 IPR036902 Ta1353-like superfamily APE_2289.1 f7ad625f6323b5311e8235c8263d031f 162 Pfam PF04008 Adenosine specific kinase 8 161 1.6E-73 T 23-10-2018 IPR007153 Adenosine specific kinase APE_2289.1 f7ad625f6323b5311e8235c8263d031f 162 Gene3D G3DSA:3.40.1520.10 1 162 7.4E-75 T 23-10-2018 IPR036902 Ta1353-like superfamily APE_1995.1 9f96536aa4f0ba0ed503417f83e7e295 193 SUPERFAMILY SSF46785 24 80 1.03E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1995.1 9f96536aa4f0ba0ed503417f83e7e295 193 Gene3D G3DSA:1.10.10.10 3 89 5.6E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 7 404 3.0E-116 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 Gene3D G3DSA:2.160.10.10 222 415 3.5E-48 T 23-10-2018 APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 SUPERFAMILY SSF51161 246 412 7.07E-29 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 SUPERFAMILY SSF53448 7 318 1.1E-50 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 Pfam PF00483 Nucleotidyl transferase 7 231 2.9E-24 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 Gene3D G3DSA:3.90.550.10 6 221 1.4E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 371 406 3.0E-5 T 23-10-2018 IPR001451 Hexapeptide repeat APE_1202.1 2c9f235775080f77d4cb9f4ca255d44b 416 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 294 3.3E-5 T 23-10-2018 IPR001451 Hexapeptide repeat APE_2342.1 040fd3feb06ba1242a5d73c610e108bb 264 SUPERFAMILY SSF55681 2 259 1.33E-52 T 23-10-2018 APE_2342.1 040fd3feb06ba1242a5d73c610e108bb 264 Pfam PF03099 Biotin/lipoate A/B protein ligase family 45 177 3.7E-25 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 APE_2342.1 040fd3feb06ba1242a5d73c610e108bb 264 Gene3D G3DSA:3.30.930.10 2 262 4.5E-55 T 23-10-2018 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 10 186 34.972 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 SUPERFAMILY SSF55267 11 88 2.35E-16 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 SUPERFAMILY SSF53032 93 183 3.49E-27 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 Gene3D G3DSA:3.40.1170.20 1 93 9.3E-35 T 23-10-2018 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 TIGRFAM TIGR00324 endA: tRNA-intron lyase 54 183 1.0E-30 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 11 85 3.8E-20 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 PIRSF PIRSF005285 13 186 4.0E-62 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 95 178 8.2E-28 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 APE_1646.1 842c7ace3d276ae8ef8949a0b269af24 186 Gene3D G3DSA:3.40.1350.10 94 186 1.8E-36 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APE_0158.1 97f27d49e16742102d7c1a8ede684a04 236 Pfam PF02219 Methylenetetrahydrofolate reductase 44 101 1.5E-4 T 23-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 APE_0158.1 97f27d49e16742102d7c1a8ede684a04 236 SUPERFAMILY SSF51730 3 99 5.1E-12 T 23-10-2018 IPR029041 FAD-linked oxidoreductase-like APE_0158.1 97f27d49e16742102d7c1a8ede684a04 236 Gene3D G3DSA:3.20.20.220 9 143 2.7E-6 T 23-10-2018 APE_0880a 73c6b9fd770aef99847b7a0e54f50c8d 94 Gene3D G3DSA:1.10.10.10 1 94 4.6E-62 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0880a 73c6b9fd770aef99847b7a0e54f50c8d 94 SUPERFAMILY SSF46785 1 92 9.79E-56 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 SUPERFAMILY SSF50615 5 72 6.87E-14 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 7 69 4.9E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 SUPERFAMILY SSF47917 456 550 6.8E-24 T 23-10-2018 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Gene3D G3DSA:2.40.50.100 123 194 9.7E-174 T 23-10-2018 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Gene3D G3DSA:2.40.30.20 2 72 1.9E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 SUPERFAMILY SSF52540 186 450 9.94E-82 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 4 591 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Gene3D G3DSA:1.10.1140.10 445 597 3.2E-44 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Gene3D G3DSA:3.40.50.300 73 444 9.7E-174 T 23-10-2018 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 85 212 2.9E-41 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 SMART SM00382 233 427 4.4E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 435 444 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 221 444 7.9E-92 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0405.1 bdaa34aeb335f2996d2bf6ce7f1dcc2d 597 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 2 594 52.933 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_2425 2f9a8c95d606b190701e149b0e612670 326 Pfam PF08544 GHMP kinases C terminal 221 302 9.9E-6 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain APE_2425 2f9a8c95d606b190701e149b0e612670 326 Gene3D G3DSA:3.30.230.10 20 157 2.8E-7 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_2425 2f9a8c95d606b190701e149b0e612670 326 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 6 323 2.0E-33 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 APE_2425 2f9a8c95d606b190701e149b0e612670 326 PIRSF PIRSF004884 1 326 3.0E-105 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 APE_2425 2f9a8c95d606b190701e149b0e612670 326 SUPERFAMILY SSF54211 5 151 2.88E-14 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_0362 79f43340cb91e0bbc589e246c50c1293 110 SUPERFAMILY SSF101744 13 94 1.15E-16 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 APE_0362 79f43340cb91e0bbc589e246c50c1293 110 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 14 92 15.823 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 APE_0362 79f43340cb91e0bbc589e246c50c1293 110 Gene3D G3DSA:2.30.30.210 6 97 6.1E-18 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 APE_0362 79f43340cb91e0bbc589e246c50c1293 110 Pfam PF01868 Domain of unknown function UPF0086 17 92 6.5E-13 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 APE_0362 79f43340cb91e0bbc589e246c50c1293 110 SMART SM00538 6 98 1.4E-39 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 APE_0502 4f61382ef6c674c9d03145faed0e7060 224 Pfam PF03587 EMG1/NEP1 methyltransferase 3 217 7.7E-41 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 APE_0502 4f61382ef6c674c9d03145faed0e7060 224 SUPERFAMILY SSF75217 2 219 7.59E-49 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_0502 4f61382ef6c674c9d03145faed0e7060 224 Gene3D G3DSA:3.40.1280.10 1 223 2.4E-65 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APE_0502 4f61382ef6c674c9d03145faed0e7060 224 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 1 218 37.594 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 1.2E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 9.4E-27 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 SMART SM00382 34 234 7.2E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 SUPERFAMILY SSF52540 34 306 1.23E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 Gene3D G3DSA:3.40.50.300 3 322 2.4E-92 T 23-10-2018 APE_0301.1 f2bf363a91d3bb1e1040aacebda4a648 322 Pfam PF00005 ABC transporter 25 184 1.5E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2542.1 63c0ad77fbcfa1791a80d2d2789a0fe8 600 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 115 550 1.0E-93 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit APE_0107 cf4ac61eefdd0d622e14d044516d867e 546 Pfam PF05872 Bacterial protein of unknown function (DUF853) 405 519 7.7E-6 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal APE_0107 cf4ac61eefdd0d622e14d044516d867e 546 Pfam PF01935 Domain of unknown function DUF87 146 380 1.2E-48 T 23-10-2018 IPR002789 Helicase HerA, central domain APE_0107 cf4ac61eefdd0d622e14d044516d867e 546 Pfam PF09378 HAS barrel domain 13 104 2.9E-10 T 23-10-2018 IPR018538 Helicase HerA, barrel domain APE_0107 cf4ac61eefdd0d622e14d044516d867e 546 SUPERFAMILY SSF52540 143 519 1.9E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0107 cf4ac61eefdd0d622e14d044516d867e 546 Gene3D G3DSA:3.40.50.300 327 528 7.7E-57 T 23-10-2018 APE_0107 cf4ac61eefdd0d622e14d044516d867e 546 Gene3D G3DSA:3.40.50.300 131 303 7.5E-20 T 23-10-2018 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 Gene3D G3DSA:3.30.360.10 151 323 1.7E-103 T 23-10-2018 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 148 164 - T 23-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 Gene3D G3DSA:3.40.50.720 6 341 1.7E-103 T 23-10-2018 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 6 355 3.4E-118 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 5 355 48.413 T 23-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 SUPERFAMILY SSF55347 153 323 1.26E-35 T 23-10-2018 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 144 6.4E-31 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 SUPERFAMILY SSF51735 5 175 1.56E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 SMART SM00859 6 145 3.7E-51 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APE_1462 ecabf5cd2a648311215c801027cb5a8d 355 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 5 349 38.876 T 23-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 SUPERFAMILY SSF51905 17 328 3.24E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 19 322 2.6E-113 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 Gene3D G3DSA:3.50.50.60 19 316 1.8E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 4.6E-36 T 23-10-2018 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 4.6E-36 T 23-10-2018 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 4.6E-36 T 23-10-2018 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 4.6E-36 T 23-10-2018 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 4.6E-36 T 23-10-2018 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 Gene3D G3DSA:3.50.50.60 131 254 1.8E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 158 182 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 154 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 248 269 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 226 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 303 322 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 52 67 6.6E-50 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 APE_1061.1 ccbda6ceeb513bc2decb3cb888ed9d33 337 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 311 4.1E-50 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_1588b c77d20ba864966f4a1401f9c54e50cd8 30 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 1 26 2.2E-5 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 APE_1588b c77d20ba864966f4a1401f9c54e50cd8 30 Gene3D G3DSA:3.30.470.20 1 28 1.4E-7 T 23-10-2018 APE_1588b c77d20ba864966f4a1401f9c54e50cd8 30 SUPERFAMILY SSF56059 1 26 7.3E-5 T 23-10-2018 APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 Gene3D G3DSA:1.10.8.60 13 288 5.9E-107 T 23-10-2018 APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 Hamap MF_01407 ORC1-type DNA replication protein. 6 385 32.07 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 SUPERFAMILY SSF46785 288 394 5.99E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 Gene3D G3DSA:3.40.50.300 29 208 5.9E-107 T 23-10-2018 APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 Pfam PF13191 AAA ATPase domain 29 110 7.0E-11 T 23-10-2018 APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 SUPERFAMILY SSF52540 13 283 2.4E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 13 374 6.1E-125 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 SMART SM00382 51 210 3.4E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 Gene3D G3DSA:1.10.10.10 296 395 1.2E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 Pfam PF09079 CDC6, C terminal winged helix domain 304 384 5.6E-21 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 APE_0475.1 9a8a2799ceadf4d6e9aff67a8c236a76 395 SMART SM01074 304 385 3.5E-31 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 Gene3D G3DSA:3.60.15.10 7 400 1.6E-102 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 Gene3D G3DSA:3.40.50.10890 197 364 1.6E-102 T 23-10-2018 APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 350 407 9.3E-14 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 SMART SM01027 229 339 7.7E-32 T 23-10-2018 IPR022712 Beta-Casp domain APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 Pfam PF00753 Metallo-beta-lactamase superfamily 14 173 5.1E-11 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 Pfam PF10996 Beta-Casp domain 240 339 6.9E-16 T 23-10-2018 IPR022712 Beta-Casp domain APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 SUPERFAMILY SSF56281 3 419 6.68E-106 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0181 9a452f2c4de561d37ef8d551d9d834ee 420 SMART SM00849 14 224 2.6E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 PRINTS PR00332 Histidine triad family signature 4 20 1.5E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 PRINTS PR00332 Histidine triad family signature 25 43 1.5E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 PRINTS PR00332 Histidine triad family signature 92 102 1.5E-11 T 23-10-2018 IPR001310 Histidine triad (HIT) protein APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 23-10-2018 IPR019808 Histidine triad, conserved site APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 SUPERFAMILY SSF54197 2 132 1.3E-36 T 23-10-2018 IPR036265 HIT-like superfamily APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 Pfam PF01230 HIT domain 11 104 2.2E-21 T 23-10-2018 IPR001310 Histidine triad (HIT) protein APE_2495.1 0eafce5dbb2f97834262e6374fcebd84 149 Gene3D G3DSA:3.30.428.10 1 135 1.0E-34 T 23-10-2018 IPR036265 HIT-like superfamily APE_0099 c7c933119b637028d65749717dff093f 959 Gene3D G3DSA:1.10.132.60 797 956 1.2E-13 T 23-10-2018 APE_0099 c7c933119b637028d65749717dff093f 959 Gene3D G3DSA:3.90.1600.10 585 777 3.0E-57 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 SUPERFAMILY SSF53098 126 531 4.43E-63 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily APE_0099 c7c933119b637028d65749717dff093f 959 Pfam PF00136 DNA polymerase family B 576 907 4.5E-46 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 Gene3D G3DSA:1.10.287.690 642 702 3.0E-57 T 23-10-2018 APE_0099 c7c933119b637028d65749717dff093f 959 SMART SM00486 308 747 5.7E-100 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 SUPERFAMILY SSF56672 538 945 3.34E-102 T 23-10-2018 APE_0099 c7c933119b637028d65749717dff093f 959 ProSitePatterns PS00116 DNA polymerase family B signature. 735 743 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 Gene3D G3DSA:3.30.420.10 311 506 2.9E-154 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 APE_0099 c7c933119b637028d65749717dff093f 959 Pfam PF03104 DNA polymerase family B, exonuclease domain 162 416 4.6E-28 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 596 609 5.1E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 681 693 5.1E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 733 741 5.1E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 APE_0099 c7c933119b637028d65749717dff093f 959 Gene3D G3DSA:3.30.342.10 132 561 2.9E-154 T 23-10-2018 APE_1986.1 09051aea8d8ec4ecf6006b67c8db2660 172 Pfam PF01467 Cytidylyltransferase-like 5 60 2.2E-10 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APE_1986.1 09051aea8d8ec4ecf6006b67c8db2660 172 Gene3D G3DSA:3.40.50.620 2 170 5.2E-34 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1986.1 09051aea8d8ec4ecf6006b67c8db2660 172 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 172 67.819 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 APE_1986.1 09051aea8d8ec4ecf6006b67c8db2660 172 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 58 9.7E-11 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APE_1986.1 09051aea8d8ec4ecf6006b67c8db2660 172 SUPERFAMILY SSF52374 2 166 9.29E-23 T 23-10-2018 APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 SUPERFAMILY SSF110324 14 65 4.45E-9 T 23-10-2018 APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 SUPERFAMILY SSF50249 67 193 9.5E-22 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 14 47 7.6E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 Gene3D G3DSA:2.40.50.140 70 160 1.3E-14 T 23-10-2018 APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 Gene3D G3DSA:2.20.70.10 161 195 2.5E-9 T 23-10-2018 APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 13 199 24.702 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 APE_0445 e1576143dfddebb461a0c1b1b335bf61 215 Gene3D G3DSA:2.40.50.100 12 63 5.1E-10 T 23-10-2018 APE_2441.1 06caf063f49e8b38038f9fe79ca9e257 595 Pfam PF07676 WD40-like Beta Propeller Repeat 109 132 5.7E-4 T 23-10-2018 IPR011659 WD40-like Beta Propeller APE_2441.1 06caf063f49e8b38038f9fe79ca9e257 595 SUPERFAMILY SSF53474 339 592 9.83E-66 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2441.1 06caf063f49e8b38038f9fe79ca9e257 595 Pfam PF00326 Prolyl oligopeptidase family 390 593 2.6E-45 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 APE_2441.1 06caf063f49e8b38038f9fe79ca9e257 595 Gene3D G3DSA:3.40.50.1820 331 594 8.1E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2441.1 06caf063f49e8b38038f9fe79ca9e257 595 Gene3D G3DSA:2.120.10.30 16 279 2.4E-21 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APE_2441.1 06caf063f49e8b38038f9fe79ca9e257 595 SUPERFAMILY SSF82171 17 334 1.8E-26 T 23-10-2018 APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 SMART SM00863 192 235 1.9E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 SUPERFAMILY SSF55186 94 238 4.71E-36 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 Gene3D G3DSA:2.40.30.130 1 90 1.3E-18 T 23-10-2018 APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 SUPERFAMILY SSF50447 2 90 1.38E-11 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 192 235 3.7E-11 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 Gene3D G3DSA:3.30.980.10 91 245 9.1E-33 T 23-10-2018 APE_0903.1 123862b475d9a1d63a281e19e303fdfe 249 Pfam PF01411 tRNA synthetases class II (A) 14 94 3.2E-10 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 Gene3D G3DSA:3.40.50.1000 9 242 1.2E-22 T 23-10-2018 IPR023214 HAD superfamily APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 Gene3D G3DSA:3.30.980.20 103 190 1.2E-22 T 23-10-2018 APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 SUPERFAMILY SSF56784 9 229 1.03E-15 T 23-10-2018 IPR036412 HAD-like superfamily APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 TIGRFAM TIGR02461 osmo_MPG_phos: mannosyl-3-phosphoglycerate phosphatase 9 237 1.1E-82 T 23-10-2018 IPR033980 Mannosyl-3-phosphoglycerate phosphatase, thermophiles GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 Hamap MF_00617 Mannosyl-3-phosphoglycerate phosphatase [mngB]. 6 258 39.702 T 23-10-2018 IPR012815 Mannosyl-3-phosphoglycerate phosphatase GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 TIGRFAM TIGR01486 HAD-SF-IIB-MPGP: mannosyl-3-phosphoglycerate phosphatase family 9 268 3.7E-82 T 23-10-2018 IPR006381 HAD-superfamily hydrolase, superfamily IIB, MPGP GO:0005737|GO:0050531|GO:0051479 KEGG: 00051+3.1.3.70|MetaCyc: PWY-5656 APE_0887.1 0847646d68e2aea5ab329b3dbefcf30b 277 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 10 236 2.0E-41 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 APE_0010.1 6d6482174676ef0eea2c4d89da7b0589 535 Pfam PF01909 Nucleotidyltransferase domain 450 529 7.8E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 APE_0010.1 6d6482174676ef0eea2c4d89da7b0589 535 PIRSF PIRSF006060 2 430 1.4E-45 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APE_0010.1 6d6482174676ef0eea2c4d89da7b0589 535 Gene3D G3DSA:1.20.1740.10 5 435 2.7E-86 T 23-10-2018 APE_0010.1 6d6482174676ef0eea2c4d89da7b0589 535 Pfam PF13520 Amino acid permease 10 389 8.5E-29 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 APE_0010.1 6d6482174676ef0eea2c4d89da7b0589 535 Gene3D G3DSA:3.30.460.10 447 535 9.1E-10 T 23-10-2018 APE_0010.1 6d6482174676ef0eea2c4d89da7b0589 535 SUPERFAMILY SSF81301 451 533 4.03E-12 T 23-10-2018 APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 SMART SM00790 8 204 6.6E-93 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 Gene3D G3DSA:1.10.599.10 244 598 8.7E-76 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 SUPERFAMILY SSF48310 212 598 1.83E-89 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 11 201 5.0E-57 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 Gene3D G3DSA:1.10.569.10 245 425 8.7E-76 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 SUPERFAMILY SSF56228 7 203 2.88E-54 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 Gene3D G3DSA:3.60.9.10 6 205 1.8E-57 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily APE_0266.1 1fd52a19a956c089ce52fdc5749e79f1 609 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 238 598 4.7E-69 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 APE_1239a f9d50fa84fa289f041fb08bc7f4a7dce 92 SUPERFAMILY SSF143430 2 80 2.09E-15 T 23-10-2018 APE_1239a f9d50fa84fa289f041fb08bc7f4a7dce 92 Gene3D G3DSA:3.30.70.240 2 68 6.0E-19 T 23-10-2018 APE_1239a f9d50fa84fa289f041fb08bc7f4a7dce 92 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 3 81 1.6E-10 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 APE_1239a f9d50fa84fa289f041fb08bc7f4a7dce 92 Pfam PF09827 CRISPR associated protein Cas2 3 69 2.1E-13 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 APE_1239a f9d50fa84fa289f041fb08bc7f4a7dce 92 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 2 90 14.675 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 APE_1533.1 1d1e8656c870fb53bd8317ca18023a99 148 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 14 148 30.819 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 APE_1533.1 1d1e8656c870fb53bd8317ca18023a99 148 SUPERFAMILY SSF75689 112 147 2.62E-11 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 APE_1533.1 1d1e8656c870fb53bd8317ca18023a99 148 SUPERFAMILY SSF100966 14 115 2.75E-24 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 APE_1533.1 1d1e8656c870fb53bd8317ca18023a99 148 Pfam PF01873 Domain found in IF2B/IF5 33 141 1.1E-33 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 APE_1533.1 1d1e8656c870fb53bd8317ca18023a99 148 SMART SM00653 33 142 5.9E-57 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 APE_1533.1 1d1e8656c870fb53bd8317ca18023a99 148 Gene3D G3DSA:3.30.70.3150 45 136 3.9E-26 T 23-10-2018 APE_2091.1 8e1f4cce11217a65bf4edfb528dd524e 320 Gene3D G3DSA:3.30.420.40 5 308 1.1E-63 T 23-10-2018 APE_2091.1 8e1f4cce11217a65bf4edfb528dd524e 320 SUPERFAMILY SSF53067 4 312 2.64E-45 T 23-10-2018 APE_2091.1 8e1f4cce11217a65bf4edfb528dd524e 320 Gene3D G3DSA:3.30.420.40 122 296 1.1E-63 T 23-10-2018 APE_2091.1 8e1f4cce11217a65bf4edfb528dd524e 320 Pfam PF00480 ROK family 5 311 1.5E-47 T 23-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 Pfam PF00579 tRNA synthetases class I (W and Y) 31 334 2.3E-44 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 PIRSF PIRSF006588 1 361 2.3E-130 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 Gene3D G3DSA:3.40.50.620 1 211 1.1E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 SUPERFAMILY SSF52374 3 342 6.1E-66 T 23-10-2018 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 154 169 2.3E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 2.3E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 171 193 2.3E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 204 216 2.3E-11 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 343 50.184 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 339 1.1E-38 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 APE_2074.1 ea226291775e22c39d0c2fe1a2cb72bb 361 Gene3D G3DSA:1.10.240.10 212 361 1.3E-51 T 23-10-2018 APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 52 353 2.7E-81 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 TIGRFAM TIGR00260 thrC: threonine synthase 38 359 3.4E-91 T 23-10-2018 IPR004450 Threonine synthase-like APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 Gene3D G3DSA:3.40.50.1100 47 359 4.8E-118 T 23-10-2018 APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 PIRSF PIRSF038945 32 384 3.4E-127 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 SUPERFAMILY SSF53686 12 363 1.44E-109 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 Gene3D G3DSA:3.40.50.1100 88 184 4.8E-118 T 23-10-2018 APE_2286 5c9b34998eaf8c9e93083ef401b96a07 393 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 80 93 - T 23-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 APE_0273a bf51a123b5d8530eee12f9556ec2455e 73 Pfam PF01954 Protein of unknown function DUF104 2 63 2.4E-21 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_0273a bf51a123b5d8530eee12f9556ec2455e 73 Gene3D G3DSA:4.10.1150.10 1 73 2.8E-9 T 23-10-2018 IPR024069 AF2212-like domain superfamily APE_0273a bf51a123b5d8530eee12f9556ec2455e 73 SUPERFAMILY SSF141694 2 49 7.85E-13 T 23-10-2018 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 15 60 7.5E-7 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 SUPERFAMILY SSF55174 9 168 3.42E-32 T 23-10-2018 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 157 33.945 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 Pfam PF01479 S4 domain 104 149 1.6E-15 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 Gene3D G3DSA:3.10.290.10 103 171 3.4E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 SMART SM01390 5 103 8.0E-20 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 162 1.4E-76 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 SMART SM00363 104 167 5.7E-10 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1739.1 b3a6d50b7b5a7a7aa1133504c3240037 171 ProSitePatterns PS00632 Ribosomal protein S4 signature. 102 126 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 SUPERFAMILY SSF51294 173 641 8.04E-31 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Gene3D G3DSA:3.10.28.10 383 536 5.3E-17 T 23-10-2018 IPR027434 Homing endonuclease APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Gene3D G3DSA:3.40.50.300 639 701 1.8E-9 T 23-10-2018 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Gene3D G3DSA:2.170.16.10 577 638 1.4E-5 T 23-10-2018 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Gene3D G3DSA:3.40.50.300 1 177 1.1E-33 T 23-10-2018 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 SMART SM00306 171 289 4.8E-13 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 617 641 6.4E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 SUPERFAMILY SSF55608 470 537 4.99E-7 T 23-10-2018 IPR027434 Homing endonuclease APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Pfam PF06745 KaiC 5 168 2.7E-37 T 23-10-2018 IPR014774 KaiC-like domain APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Pfam PF06745 KaiC 641 699 7.8E-9 T 23-10-2018 IPR014774 KaiC-like domain APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 178 263 7.8E-8 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 TIGRFAM TIGR03881 KaiC_arch_4: KaiC domain protein, PAE1156 family 2 173 1.6E-82 T 23-10-2018 IPR022443 KaiC-related APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR00379 Intein signature 386 398 1.1E-15 T 23-10-2018 IPR006142 Intein GO:0016539 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR00379 Intein signature 615 632 1.1E-15 T 23-10-2018 IPR006142 Intein GO:0016539 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR00379 Intein signature 484 496 1.1E-15 T 23-10-2018 IPR006142 Intein GO:0016539 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR00379 Intein signature 635 644 1.1E-15 T 23-10-2018 IPR006142 Intein GO:0016539 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR00379 Intein signature 512 527 1.1E-15 T 23-10-2018 IPR006142 Intein GO:0016539 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR00379 Intein signature 251 264 1.1E-15 T 23-10-2018 IPR006142 Intein GO:0016539 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR01874 DNA repair protein radA signature 13 41 4.0E-5 T 23-10-2018 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 PRINTS PR01874 DNA repair protein radA signature 55 72 4.0E-5 T 23-10-2018 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 SUPERFAMILY SSF52540 1 700 7.19E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Gene3D G3DSA:2.170.16.10 178 306 4.2E-24 T 23-10-2018 APE_0745.1 3eeac204f32347c571d7fba3461484d6 723 Pfam PF14890 Intein splicing domain 191 640 2.2E-20 T 23-10-2018 APE_1694.1 92162528b9c2c094679efabf91ac1d70 150 Pfam PF02628 Cytochrome oxidase assembly protein 59 136 3.4E-7 T 23-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 APE_1694.1 92162528b9c2c094679efabf91ac1d70 150 Pfam PF02628 Cytochrome oxidase assembly protein 11 55 9.5E-10 T 23-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 APE_0392 3e457bdc717d0432e2fcfca564317272 446 SUPERFAMILY SSF53223 17 166 6.04E-46 T 23-10-2018 APE_0392 3e457bdc717d0432e2fcfca564317272 446 PIRSF PIRSF000106 38 116 6.4E-8 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APE_0392 3e457bdc717d0432e2fcfca564317272 446 PIRSF PIRSF000106 120 433 1.5E-64 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 APE_0392 3e457bdc717d0432e2fcfca564317272 446 Pfam PF03949 Malic enzyme, NAD binding domain 169 402 1.1E-25 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 APE_0392 3e457bdc717d0432e2fcfca564317272 446 Gene3D G3DSA:3.40.50.10380 6 165 6.2E-58 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 APE_0392 3e457bdc717d0432e2fcfca564317272 446 SMART SM01274 23 156 3.8E-61 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 APE_0392 3e457bdc717d0432e2fcfca564317272 446 Pfam PF00390 Malic enzyme, N-terminal domain 24 115 2.3E-14 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 APE_0392 3e457bdc717d0432e2fcfca564317272 446 Gene3D G3DSA:3.40.50.720 166 445 9.2E-86 T 23-10-2018 APE_0392 3e457bdc717d0432e2fcfca564317272 446 SUPERFAMILY SSF51735 168 430 4.65E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0392 3e457bdc717d0432e2fcfca564317272 446 SMART SM00919 168 404 6.4E-110 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 131 243 6.0E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 Gene3D G3DSA:1.10.150.190 95 184 8.2E-26 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 SUPERFAMILY SSF50249 19 97 1.17E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 Gene3D G3DSA:3.30.70.1130 185 276 3.1E-23 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 SMART SM00316 20 93 2.2E-14 T 23-10-2018 IPR022967 RNA-binding domain, S1 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 Pfam PF00575 S1 RNA binding domain 19 93 5.6E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 Gene3D G3DSA:2.40.50.140 10 94 4.3E-24 T 23-10-2018 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 13 276 33.8 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 SUPERFAMILY SSF116742 95 184 2.35E-23 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 APE_0436.1 8f7a0279366cf8e443847e409506b8bd 277 SUPERFAMILY SSF110993 187 273 1.7E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 APE_1143 16345929946fb002db54bcc342137178 349 Gene3D G3DSA:3.30.360.10 148 325 8.0E-119 T 23-10-2018 APE_1143 16345929946fb002db54bcc342137178 349 PIRSF PIRSF000148 1 348 9.4E-95 T 23-10-2018 APE_1143 16345929946fb002db54bcc342137178 349 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 1 343 2.5E-151 T 23-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 APE_1143 16345929946fb002db54bcc342137178 349 SMART SM00859 2 130 1.2E-27 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APE_1143 16345929946fb002db54bcc342137178 349 SUPERFAMILY SSF55347 146 330 1.37E-41 T 23-10-2018 APE_1143 16345929946fb002db54bcc342137178 349 Gene3D G3DSA:3.40.50.720 2 340 8.0E-119 T 23-10-2018 APE_1143 16345929946fb002db54bcc342137178 349 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 157 328 2.0E-32 T 23-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APE_1143 16345929946fb002db54bcc342137178 349 SUPERFAMILY SSF51735 2 175 2.11E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1143 16345929946fb002db54bcc342137178 349 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 128 2.7E-26 T 23-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 Pfam PF01170 Putative RNA methylase family UPF0020 170 343 1.9E-47 T 23-10-2018 IPR000241 Putative RNA methylase domain APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 203 214 - T 23-10-2018 IPR000241 Putative RNA methylase domain APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 Gene3D G3DSA:3.40.50.150 170 349 7.6E-27 T 23-10-2018 APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 SUPERFAMILY SSF53335 173 331 2.86E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 269 275 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 201 215 9.0E-7 T 23-10-2018 APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 266 278 9.0E-7 T 23-10-2018 APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 288 312 9.0E-7 T 23-10-2018 APE_1835 2e5f4cabe538c1119a796f0984844ac4 350 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 4 347 1.9E-124 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 260 276 7.2E-39 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 228 249 7.2E-39 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 204 221 7.2E-39 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 102 113 7.2E-39 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 131 148 7.2E-39 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 149 164 7.2E-39 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 SUPERFAMILY SSF56726 77 388 3.79E-89 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 Gene3D G3DSA:3.40.1360.10 158 389 9.5E-83 T 23-10-2018 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 12 388 38.976 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 Gene3D G3DSA:1.10.10.10 3 157 3.2E-51 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 Pfam PF04406 Type IIB DNA topoisomerase 78 154 8.1E-21 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 125 142 1.9E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 178 196 1.9E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 359 382 1.9E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 44 64 1.9E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 APE_0703.1 bccb262db97950a8e19987d1ca9f8fd0 389 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 234 254 1.9E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 APE_2032.1 90bf11a5bd18aff15de565b592c65d02 357 SUPERFAMILY SSF101307 212 351 1.7E-22 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 APE_2032.1 90bf11a5bd18aff15de565b592c65d02 357 Gene3D G3DSA:1.10.3760.10 213 357 2.3E-5 T 23-10-2018 APE_2032.1 90bf11a5bd18aff15de565b592c65d02 357 PIRSF PIRSF027887 1 357 4.1E-182 T 23-10-2018 IPR021167 Uncharacterised conserved protein, UCP027887, phosphatidlglycerophosphatase-related APE_2032.1 90bf11a5bd18aff15de565b592c65d02 357 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 208 352 7.9E-50 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ APE_2032.1 90bf11a5bd18aff15de565b592c65d02 357 Pfam PF01955 Adenosylcobinamide amidohydrolase 18 194 1.4E-32 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ APE_2517.1 ba6d42fe417f78be438370ce3a00aa77 135 Pfam PF01638 HxlR-like helix-turn-helix 14 102 8.6E-24 T 23-10-2018 IPR002577 Helix-turn-helix, HxlR type APE_2517.1 ba6d42fe417f78be438370ce3a00aa77 135 SMART SM00418 10 94 0.0064 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_2517.1 ba6d42fe417f78be438370ce3a00aa77 135 SUPERFAMILY SSF46785 4 102 5.56E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2517.1 ba6d42fe417f78be438370ce3a00aa77 135 Gene3D G3DSA:1.10.10.10 1 133 4.6E-34 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0751 016e58197d4594d9d727e304c52da61a 266 Gene3D G3DSA:1.10.510.10 156 256 1.4E-26 T 23-10-2018 APE_0751 016e58197d4594d9d727e304c52da61a 266 Pfam PF01163 RIO1 family 62 250 2.1E-62 T 23-10-2018 APE_0751 016e58197d4594d9d727e304c52da61a 266 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 APE_0751 016e58197d4594d9d727e304c52da61a 266 SUPERFAMILY SSF56112 51 239 4.04E-22 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily APE_0751 016e58197d4594d9d727e304c52da61a 266 Gene3D G3DSA:3.30.200.20 48 150 3.3E-11 T 23-10-2018 APE_0751 016e58197d4594d9d727e304c52da61a 266 SMART SM00090 20 258 2.5E-72 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 APE_0337.1 a3178653fea994f89797821413e77d0f 332 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 5 327 6.7E-69 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 APE_0337.1 a3178653fea994f89797821413e77d0f 332 SUPERFAMILY SSF51556 3 329 5.16E-65 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_0337.1 a3178653fea994f89797821413e77d0f 332 Gene3D G3DSA:3.20.20.140 1 331 6.1E-72 T 23-10-2018 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 Gene3D G3DSA:3.40.190.10 102 201 1.0E-55 T 23-10-2018 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 1.4E-28 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 PRINTS PR00151 Porphobilinogen deaminase signature 124 141 1.4E-28 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 1.4E-28 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 PRINTS PR00151 Porphobilinogen deaminase signature 143 160 1.4E-28 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 1.4E-28 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 207 2.3E-54 T 23-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 SUPERFAMILY SSF54782 220 295 6.02E-14 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 Gene3D G3DSA:3.30.160.40 223 300 2.2E-11 T 23-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 226 293 4.0E-10 T 23-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 PIRSF PIRSF001438 1 301 2.9E-83 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 23-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 Gene3D G3DSA:3.40.190.10 3 206 1.0E-55 T 23-10-2018 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 296 32.57 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 294 8.9E-74 T 23-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_2298.1 a235656a92bb97e2ddfd35d8e8eb8bcd 307 SUPERFAMILY SSF53850 2 209 2.39E-53 T 23-10-2018 APE_0050 2786f699c2a92c1163937776c3e57924 253 SMART SM00382 30 226 5.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0050 2786f699c2a92c1163937776c3e57924 253 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0050 2786f699c2a92c1163937776c3e57924 253 SUPERFAMILY SSF52540 6 240 3.19E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0050 2786f699c2a92c1163937776c3e57924 253 Pfam PF00005 ABC transporter 21 177 8.1E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0050 2786f699c2a92c1163937776c3e57924 253 Gene3D G3DSA:3.40.50.300 6 252 3.0E-74 T 23-10-2018 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 SMART SM01376 69 135 4.1E-21 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 Gene3D G3DSA:2.40.50.140 69 136 3.8E-24 T 23-10-2018 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 Gene3D G3DSA:2.30.30.30 1 68 9.6E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 34 41 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 SUPERFAMILY SSF50249 69 134 3.73E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 38 3.1E-5 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 PIRSF PIRSF003025 1 139 6.4E-49 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 8 134 2.7E-43 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 SUPERFAMILY SSF50104 2 77 2.66E-21 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 2 134 34.258 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal APE_2085.1 8206f2948fae567454f4d9fce629bea1 139 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 69 135 6.5E-12 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 APE_1786.1 957b7506e1083fcc4387e6a61a69074b 510 Pfam PF00171 Aldehyde dehydrogenase family 42 497 2.1E-120 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APE_1786.1 957b7506e1083fcc4387e6a61a69074b 510 Gene3D G3DSA:3.40.309.10 273 473 6.4E-136 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APE_1786.1 957b7506e1083fcc4387e6a61a69074b 510 SUPERFAMILY SSF53720 26 503 4.06E-129 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APE_1786.1 957b7506e1083fcc4387e6a61a69074b 510 Gene3D G3DSA:3.40.605.10 44 272 6.4E-136 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APE_1055.1 7c08422a97eaaf318dd07185eee87b4c 249 Pfam PF00005 ABC transporter 22 164 2.4E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1055.1 7c08422a97eaaf318dd07185eee87b4c 249 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1055.1 7c08422a97eaaf318dd07185eee87b4c 249 SMART SM00382 31 211 9.5E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1055.1 7c08422a97eaaf318dd07185eee87b4c 249 SUPERFAMILY SSF52540 6 223 7.01E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1055.1 7c08422a97eaaf318dd07185eee87b4c 249 Gene3D G3DSA:3.40.50.300 4 240 2.7E-53 T 23-10-2018 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 14 302 1.2E-66 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 Gene3D G3DSA:3.40.50.2020 8 154 6.2E-35 T 23-10-2018 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 10 296 34.07 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 Gene3D G3DSA:3.40.50.2020 157 292 3.6E-30 T 23-10-2018 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 14 126 9.0E-18 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 Pfam PF00156 Phosphoribosyl transferase domain 167 256 1.7E-13 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 SMART SM01400 8 126 2.7E-25 T 23-10-2018 APE_1834.1 ba0aa311e2253f67b82e8f5461dde38d 309 SUPERFAMILY SSF53271 77 296 8.68E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 PRINTS PR00395 Ribosomal protein S2 signature 115 132 6.3E-20 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 PRINTS PR00395 Ribosomal protein S2 signature 90 107 6.3E-20 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 PRINTS PR00395 Ribosomal protein S2 signature 153 167 6.3E-20 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 PRINTS PR00395 Ribosomal protein S2 signature 132 143 6.3E-20 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 4 202 46.792 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 115 139 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 Gene3D G3DSA:3.40.50.10490 11 203 2.1E-59 T 23-10-2018 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 SUPERFAMILY SSF52313 8 196 3.79E-57 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 7 202 3.6E-98 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1750 3ad4199438cfd0acc31fdf61977afa45 205 Pfam PF00318 Ribosomal protein S2 114 178 4.4E-17 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_2436a 517948bf995ca8ea4e876abcfcf1c9df 114 Gene3D G3DSA:3.30.1050.10 1 110 9.4E-26 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily APE_2436a 517948bf995ca8ea4e876abcfcf1c9df 114 Pfam PF02036 SCP-2 sterol transfer family 13 107 7.2E-18 T 23-10-2018 IPR003033 SCP2 sterol-binding domain APE_2436a 517948bf995ca8ea4e876abcfcf1c9df 114 SUPERFAMILY SSF55718 12 109 4.0E-21 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily APE_1294.1 9cb62e93e7f2ad1d8068e8d6febc7efc 464 Pfam PF13247 4Fe-4S dicluster domain 162 259 4.0E-36 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_1294.1 9cb62e93e7f2ad1d8068e8d6febc7efc 464 Gene3D G3DSA:1.10.3650.10 345 427 2.0E-19 T 23-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 APE_1294.1 9cb62e93e7f2ad1d8068e8d6febc7efc 464 Gene3D G3DSA:3.30.70.20 1 286 3.3E-97 T 23-10-2018 APE_1294.1 9cb62e93e7f2ad1d8068e8d6febc7efc 464 SUPERFAMILY SSF54862 2 457 2.62E-131 T 23-10-2018 APE_1294.1 9cb62e93e7f2ad1d8068e8d6febc7efc 464 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 2 455 3.7E-190 T 23-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 APE_1294.1 9cb62e93e7f2ad1d8068e8d6febc7efc 464 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 345 428 4.8E-24 T 23-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 255 492 2.5E-60 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 SUPERFAMILY SSF52518 240 502 5.89E-55 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_2126.1 72de4da438c112790f263e3995bcd7be 639 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 216 1.5E-35 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 SUPERFAMILY SSF52922 514 632 6.63E-20 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 4 621 8.5E-171 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 522 592 5.2E-8 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II APE_2126.1 72de4da438c112790f263e3995bcd7be 639 Gene3D G3DSA:3.40.50.970 228 437 2.8E-68 T 23-10-2018 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 SUPERFAMILY SSF53323 9 260 4.18E-8 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 APE_2126.1 72de4da438c112790f263e3995bcd7be 639 Gene3D G3DSA:3.40.50.920 510 627 2.8E-29 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 APE_0260.1 1812b7c99d31e8e9eeba12a2b7bbf9d0 306 PIRSF PIRSF000164 1 305 1.1E-85 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 APE_0260.1 1812b7c99d31e8e9eeba12a2b7bbf9d0 306 SUPERFAMILY SSF51395 2 304 5.19E-74 T 23-10-2018 APE_0260.1 1812b7c99d31e8e9eeba12a2b7bbf9d0 306 Pfam PF01180 Dihydroorotate dehydrogenase 7 287 2.7E-50 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 APE_0260.1 1812b7c99d31e8e9eeba12a2b7bbf9d0 306 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 7 304 3.7E-89 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 APE_0260.1 1812b7c99d31e8e9eeba12a2b7bbf9d0 306 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 7 303 33.83 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 APE_0260.1 1812b7c99d31e8e9eeba12a2b7bbf9d0 306 Gene3D G3DSA:3.20.20.70 2 305 3.0E-81 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2438 ff52e3c686e1a241cc0ec66e6260393b 515 SUPERFAMILY SSF51717 174 373 6.87E-9 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APE_2438 ff52e3c686e1a241cc0ec66e6260393b 515 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 16 502 1.1E-224 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein APE_2446 49db232090f46dd18ce7cea2e2da479e 365 SUPERFAMILY SSF51998 3 364 4.12E-61 T 23-10-2018 APE_2446 49db232090f46dd18ce7cea2e2da479e 365 Pfam PF05167 Uncharacterised ACR (DUF711) 146 352 1.6E-23 T 23-10-2018 IPR007841 Uncharacterised protein family UPF0210 APE_2446 49db232090f46dd18ce7cea2e2da479e 365 PIRSF PIRSF027893 6 365 4.6E-149 T 23-10-2018 IPR014537 Uncharacterised conserved protein UCP027893 APE_2446 49db232090f46dd18ce7cea2e2da479e 365 Gene3D G3DSA:3.20.70.20 1 365 3.3E-41 T 23-10-2018 APE_2458 456f98c11bbd48061dbb009390e3225f 432 SMART SM01193 8 137 7.7E-70 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 SUPERFAMILY SSF54826 8 139 1.06E-42 T 23-10-2018 APE_2458 456f98c11bbd48061dbb009390e3225f 432 Pfam PF00113 Enolase, C-terminal TIM barrel domain 145 424 3.8E-106 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 SMART SM01192 142 428 3.0E-168 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 Hamap MF_00318 Enolase [eno]. 6 414 41.905 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PRINTS PR00148 Enolase signature 337 351 8.6E-40 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PRINTS PR00148 Enolase signature 41 55 8.6E-40 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PRINTS PR00148 Enolase signature 164 177 8.6E-40 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PRINTS PR00148 Enolase signature 110 126 8.6E-40 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PRINTS PR00148 Enolase signature 314 325 8.6E-40 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PRINTS PR00148 Enolase signature 366 383 8.6E-40 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 Gene3D G3DSA:3.20.20.120 131 430 7.5E-119 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily APE_2458 456f98c11bbd48061dbb009390e3225f 432 Gene3D G3DSA:3.30.390.10 6 129 1.1E-41 T 23-10-2018 IPR029017 Enolase-like, N-terminal APE_2458 456f98c11bbd48061dbb009390e3225f 432 SUPERFAMILY SSF51604 142 425 2.55E-108 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily APE_2458 456f98c11bbd48061dbb009390e3225f 432 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 APE_2458 456f98c11bbd48061dbb009390e3225f 432 PIRSF PIRSF001400 4 427 3.4E-177 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 Pfam PF03952 Enolase, N-terminal domain 8 137 1.5E-44 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_2458 456f98c11bbd48061dbb009390e3225f 432 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 8 423 2.6E-160 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 APE_0352.1 1626f14067f45c6463e41200a48fb97b 133 Gene3D G3DSA:3.30.1370.30 1 69 3.0E-30 T 23-10-2018 APE_0352.1 1626f14067f45c6463e41200a48fb97b 133 Gene3D G3DSA:3.30.1490.10 70 133 6.8E-19 T 23-10-2018 APE_0352.1 1626f14067f45c6463e41200a48fb97b 133 Pfam PF00410 Ribosomal protein S8 5 133 1.1E-27 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0352.1 1626f14067f45c6463e41200a48fb97b 133 SUPERFAMILY SSF56047 2 133 3.4E-38 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0352.1 1626f14067f45c6463e41200a48fb97b 133 ProSitePatterns PS00053 Ribosomal protein S8 signature. 103 120 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0352.1 1626f14067f45c6463e41200a48fb97b 133 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 133 35.671 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 72 554 4.6E-74 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 SUPERFAMILY SSF81665 52 533 3.66E-7 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 Gene3D G3DSA:3.40.50.1000 269 512 9.7E-57 T 23-10-2018 IPR023214 HAD superfamily APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 Gene3D G3DSA:2.70.150.20 99 200 1.1E-22 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 49 576 2.0E-137 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 SUPERFAMILY SSF81653 102 196 7.32E-19 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 SUPERFAMILY SSF56784 288 562 4.62E-37 T 23-10-2018 IPR036412 HAD-like superfamily APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 291 297 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 49 578 6.6E-135 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 Pfam PF00122 E1-E2 ATPase 100 268 2.8E-35 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 Pfam PF00702 haloacid dehalogenase-like hydrolase 285 491 1.4E-28 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 Gene3D G3DSA:3.40.1110.10 299 409 9.7E-57 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 148 162 1.2E-13 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 477 496 1.2E-13 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 289 303 1.2E-13 T 23-10-2018 APE_2571.1 6fac8df1e1023c8c994e182eddcdb714 585 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 424 434 1.2E-13 T 23-10-2018 APE_1345 1552589b6b2925a2506603b4d9fffbb9 197 Pfam PF00892 EamA-like transporter family 59 194 2.2E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_1345 1552589b6b2925a2506603b4d9fffbb9 197 SUPERFAMILY SSF103481 93 196 4.71E-16 T 23-10-2018 APE_1211.1 eafd3f461d99961ec1929686d4b478c4 124 Gene3D G3DSA:1.10.10.10 28 122 4.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1211.1 eafd3f461d99961ec1929686d4b478c4 124 SUPERFAMILY SSF46785 21 114 2.18E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1732 4b8d704b7735cf475049e762449e49bb 358 SMART SM00382 28 211 6.2E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1732 4b8d704b7735cf475049e762449e49bb 358 Pfam PF08402 TOBE domain 280 349 8.0E-10 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 APE_1732 4b8d704b7735cf475049e762449e49bb 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1732 4b8d704b7735cf475049e762449e49bb 358 Gene3D G3DSA:2.40.50.100 247 352 8.3E-7 T 23-10-2018 APE_1732 4b8d704b7735cf475049e762449e49bb 358 SUPERFAMILY SSF50331 244 356 1.87E-15 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APE_1732 4b8d704b7735cf475049e762449e49bb 358 Pfam PF00005 ABC transporter 19 161 2.1E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1732 4b8d704b7735cf475049e762449e49bb 358 SUPERFAMILY SSF52540 4 240 1.21E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1732 4b8d704b7735cf475049e762449e49bb 358 Gene3D G3DSA:3.40.50.300 1 238 1.5E-78 T 23-10-2018 APE_1732 4b8d704b7735cf475049e762449e49bb 358 Gene3D G3DSA:2.40.50.140 299 343 8.3E-7 T 23-10-2018 APE_0382 45762f8f0d01014e9e22e2a72d8e7e0f 229 Gene3D G3DSA:3.60.15.10 6 214 1.2E-28 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0382 45762f8f0d01014e9e22e2a72d8e7e0f 229 SMART SM00849 14 196 2.1E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0382 45762f8f0d01014e9e22e2a72d8e7e0f 229 Pfam PF00753 Metallo-beta-lactamase superfamily 17 194 1.7E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0382 45762f8f0d01014e9e22e2a72d8e7e0f 229 SUPERFAMILY SSF56281 2 211 3.93E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0104.1 7ce2c78b7bb5b240d28b95cc0c82b5a2 259 Pfam PF09754 PAC2 family 29 233 7.3E-35 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 APE_0104.1 7ce2c78b7bb5b240d28b95cc0c82b5a2 259 Gene3D G3DSA:3.40.50.10900 17 252 1.4E-44 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily APE_0104.1 7ce2c78b7bb5b240d28b95cc0c82b5a2 259 SUPERFAMILY SSF159659 8 244 2.75E-38 T 23-10-2018 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 Gene3D G3DSA:3.40.50.1950 19 186 4.3E-38 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 SUPERFAMILY SSF52507 22 220 7.33E-42 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 Gene3D G3DSA:3.40.50.10300 188 412 2.0E-56 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 196 375 1.3E-47 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 21 406 2.2E-86 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 Pfam PF02441 Flavoprotein 23 180 6.2E-33 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 APE_1959.1 af3c1bc158551b3c572926afbb580c83 412 SUPERFAMILY SSF102645 194 411 7.06E-52 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 SUPERFAMILY SSF55681 338 542 2.61E-42 T 23-10-2018 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 539 33.273 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 SUPERFAMILY SSF46955 277 345 2.84E-14 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Pfam PF03483 B3/4 domain 111 237 7.9E-6 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Gene3D G3DSA:3.30.56.10 274 341 3.7E-16 T 23-10-2018 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 SMART SM00874 273 341 1.1E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 SMART SM00874 1 65 0.031 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Gene3D G3DSA:3.50.40.10 79 268 1.3E-42 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 SMART SM00873 91 250 6.6E-9 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Pfam PF03484 tRNA synthetase B5 domain 278 341 1.1E-13 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Gene3D G3DSA:3.30.56.10 1 73 1.6E-13 T 23-10-2018 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 SUPERFAMILY SSF46955 4 69 1.1E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 2 541 3.2E-115 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 APE_2305 6a6ddd105872eaaefb187548ef0b2b18 548 Gene3D G3DSA:3.30.930.10 359 543 4.9E-49 T 23-10-2018 APE_2279.1 2db83258fac235a89628d9d8337cf124 634 Gene3D G3DSA:3.30.230.10 34 227 2.2E-21 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_2279.1 2db83258fac235a89628d9d8337cf124 634 SUPERFAMILY SSF54211 43 226 5.31E-20 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_2279.1 2db83258fac235a89628d9d8337cf124 634 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 110 176 9.7E-10 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 APE_1272.1 b8cf54bdf84a9f7f9b4e98d07126afd7 139 Pfam PF05168 HEPN domain 10 130 3.1E-34 T 23-10-2018 IPR007842 HEPN domain APE_1272.1 b8cf54bdf84a9f7f9b4e98d07126afd7 139 SUPERFAMILY SSF81593 6 131 9.81E-41 T 23-10-2018 APE_1272.1 b8cf54bdf84a9f7f9b4e98d07126afd7 139 SMART SM00748 12 124 1.6E-46 T 23-10-2018 IPR007842 HEPN domain APE_1272.1 b8cf54bdf84a9f7f9b4e98d07126afd7 139 Gene3D G3DSA:1.20.120.330 4 133 3.5E-36 T 23-10-2018 APE_1867.1 7bac05591c737dd82eecfb90cbc3bcef 286 SUPERFAMILY SSF50182 106 166 6.54E-14 T 23-10-2018 IPR010920 LSM domain superfamily APE_1867.1 7bac05591c737dd82eecfb90cbc3bcef 286 Gene3D G3DSA:2.30.30.60 120 167 8.2E-9 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily APE_1867.1 7bac05591c737dd82eecfb90cbc3bcef 286 Pfam PF00924 Mechanosensitive ion channel 62 258 6.7E-41 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 APE_1867.1 7bac05591c737dd82eecfb90cbc3bcef 286 SUPERFAMILY SSF82861 22 103 4.05E-9 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 APE_1867.1 7bac05591c737dd82eecfb90cbc3bcef 286 Gene3D G3DSA:3.30.70.100 171 263 7.7E-14 T 23-10-2018 APE_1867.1 7bac05591c737dd82eecfb90cbc3bcef 286 SUPERFAMILY SSF82689 175 269 5.1E-17 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 APE_2326.1 dbf9f9ec16e1ce99215c5f45030f1369 102 Pfam PF00137 ATP synthase subunit C 39 98 8.0E-18 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 APE_2326.1 dbf9f9ec16e1ce99215c5f45030f1369 102 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 50 76 6.9E-10 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_2326.1 dbf9f9ec16e1ce99215c5f45030f1369 102 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 77 100 6.9E-10 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_2326.1 dbf9f9ec16e1ce99215c5f45030f1369 102 SUPERFAMILY SSF81333 33 99 3.01E-15 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily APE_2326.1 dbf9f9ec16e1ce99215c5f45030f1369 102 Gene3D G3DSA:1.20.120.610 1 101 1.6E-16 T 23-10-2018 APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 SUPERFAMILY SSF75445 134 211 9.81E-18 T 23-10-2018 APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 27 221 3.6E-40 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 229 27.424 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 Gene3D G3DSA:3.30.70.260 130 208 2.4E-47 T 23-10-2018 APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 Gene3D G3DSA:3.40.50.1360 27 220 2.4E-47 T 23-10-2018 APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 SUPERFAMILY SSF100950 10 153 1.12E-21 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_0665 b7251d6a4b18e0d646099f1898e9073c 237 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 220 5.9E-44 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 APE_0816 77dbc292a5e8a0b325978340576e1d04 188 Gene3D G3DSA:3.30.1960.10 18 188 3.8E-55 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 APE_0816 77dbc292a5e8a0b325978340576e1d04 188 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 184 25.044 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 APE_0816 77dbc292a5e8a0b325978340576e1d04 188 Pfam PF02676 Methyltransferase TYW3 12 182 1.3E-26 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 APE_0816 77dbc292a5e8a0b325978340576e1d04 188 SUPERFAMILY SSF111278 6 181 8.63E-45 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 APE_0697 5c9ddeae97145edd8985d64490bc262b 142 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 28 2.3E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal APE_2021.1 f97413241dbece1653680528be8c0815 139 SUPERFAMILY SSF46785 9 128 3.29E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2021.1 f97413241dbece1653680528be8c0815 139 Pfam PF01475 Ferric uptake regulator family 15 126 1.9E-20 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 APE_2021.1 f97413241dbece1653680528be8c0815 139 Gene3D G3DSA:1.10.10.10 3 85 1.8E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 SUPERFAMILY SSF53223 4 182 8.96E-66 T 23-10-2018 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 Gene3D G3DSA:3.40.50.720 180 418 6.1E-82 T 23-10-2018 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 180 416 6.5E-72 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 SMART SM00839 182 416 1.9E-93 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 PIRSF PIRSF000185 2 418 1.0E-159 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 340 351 1.7E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 171 193 1.7E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 1.7E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 213 233 1.7E-33 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 SUPERFAMILY SSF51735 180 417 2.24E-71 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 8.7E-52 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 APE_1386.1 e8b45f0a08687edd79ae25978c355d73 418 Gene3D G3DSA:3.40.50.10860 36 179 1.4E-58 T 23-10-2018 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 SUPERFAMILY SSF54984 1 89 4.45E-23 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 PIRSF PIRSF006521 1 89 3.5E-33 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 SMART SM00888 3 89 6.7E-37 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 89 1.7E-18 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 90 39.798 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 Gene3D G3DSA:3.30.70.60 1 90 1.1E-28 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 APE_2480.1 52ac715cf96e5e1897490187a966f8cd 90 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 88 3.6E-23 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 APE_1648.1 0a545eac3b0fd7176c745afd0390e2ab 189 Gene3D G3DSA:3.40.220.10 5 169 2.2E-37 T 23-10-2018 APE_1648.1 0a545eac3b0fd7176c745afd0390e2ab 189 SMART SM00506 10 138 1.9E-44 T 23-10-2018 IPR002589 Macro domain APE_1648.1 0a545eac3b0fd7176c745afd0390e2ab 189 SUPERFAMILY SSF52949 4 167 2.19E-38 T 23-10-2018 APE_1648.1 0a545eac3b0fd7176c745afd0390e2ab 189 Pfam PF01661 Macro domain 27 136 1.7E-26 T 23-10-2018 IPR002589 Macro domain APE_0930.1 fa47171d1d11567ab3c72f6db21ed75c 179 Gene3D G3DSA:1.10.12.20 31 101 1.3E-12 T 23-10-2018 APE_0930.1 fa47171d1d11567ab3c72f6db21ed75c 179 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 98 160 5.6E-13 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal APE_0930.1 fa47171d1d11567ab3c72f6db21ed75c 179 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 61 95 4.6E-8 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal APE_0930.1 fa47171d1d11567ab3c72f6db21ed75c 179 SUPERFAMILY SSF50249 38 168 4.63E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0204.1 6998dccf8b889e8cb01afb87f009b769 220 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 35 208 34.66 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 APE_0204.1 6998dccf8b889e8cb01afb87f009b769 220 Gene3D G3DSA:1.10.10.970 35 107 6.3E-28 T 23-10-2018 APE_0204.1 6998dccf8b889e8cb01afb87f009b769 220 Gene3D G3DSA:3.20.170.30 127 220 2.3E-33 T 23-10-2018 APE_0204.1 6998dccf8b889e8cb01afb87f009b769 220 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 36 197 8.4E-24 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 APE_0204.1 6998dccf8b889e8cb01afb87f009b769 220 SUPERFAMILY SSF56399 37 209 6.62E-51 T 23-10-2018 APE_2284.1 01388d89234956883005b439143d6b59 550 SUPERFAMILY SSF56801 48 543 7.98E-150 T 23-10-2018 APE_2284.1 01388d89234956883005b439143d6b59 550 Gene3D G3DSA:3.30.300.310 443 548 1.2E-31 T 23-10-2018 APE_2284.1 01388d89234956883005b439143d6b59 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 23-10-2018 IPR020845 AMP-binding, conserved site APE_2284.1 01388d89234956883005b439143d6b59 550 Pfam PF00501 AMP-binding enzyme 48 447 4.6E-106 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_2284.1 01388d89234956883005b439143d6b59 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 1.6E-18 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APE_2284.1 01388d89234956883005b439143d6b59 550 Gene3D G3DSA:3.40.50.12780 43 438 3.5E-120 T 23-10-2018 APE_1483.1 99893ab2a876a06915407cb073dc9239 279 Gene3D G3DSA:3.40.630.50 2 184 5.7E-42 T 23-10-2018 APE_1483.1 99893ab2a876a06915407cb073dc9239 279 SUPERFAMILY SSF142535 4 277 1.05E-70 T 23-10-2018 APE_1483.1 99893ab2a876a06915407cb073dc9239 279 Gene3D G3DSA:3.40.50.10700 192 278 2.9E-22 T 23-10-2018 APE_1483.1 99893ab2a876a06915407cb073dc9239 279 Pfam PF04414 D-aminoacyl-tRNA deacylase 66 276 7.7E-63 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 APE_1483.1 99893ab2a876a06915407cb073dc9239 279 PIRSF PIRSF016210 2 279 1.4E-74 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 APE_1483.1 99893ab2a876a06915407cb073dc9239 279 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 2 278 34.056 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Gene3D G3DSA:2.40.30.10 322 428 1.8E-40 T 23-10-2018 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 SUPERFAMILY SSF50465 324 428 1.01E-37 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 3 431 3.4E-212 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 SUPERFAMILY SSF52540 2 248 1.05E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Hamap MF_00118_A Elongation factor Tu [tuf]. 1 430 62.703 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Pfam PF00009 Elongation factor Tu GTP binding domain 4 222 3.4E-57 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Gene3D G3DSA:2.40.30.10 228 321 2.3E-39 T 23-10-2018 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Gene3D G3DSA:3.40.50.300 1 225 7.4E-94 T 23-10-2018 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 SUPERFAMILY SSF50447 230 321 8.73E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Pfam PF03143 Elongation factor Tu C-terminal domain 321 427 2.6E-34 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 PRINTS PR00315 GTP-binding elongation factor signature 103 114 5.5E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 PRINTS PR00315 GTP-binding elongation factor signature 147 156 5.5E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 PRINTS PR00315 GTP-binding elongation factor signature 8 21 5.5E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 PRINTS PR00315 GTP-binding elongation factor signature 87 97 5.5E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 PRINTS PR00315 GTP-binding elongation factor signature 67 75 5.5E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 Pfam PF03144 Elongation factor Tu domain 2 247 312 7.6E-16 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 APE_1844 496b11d04423d3a4ab0e9afabc94ac56 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 200 3.5E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 APE_1324 1c353511ff9e855ecf89c7d114625725 174 SUPERFAMILY SSF55729 5 149 6.08E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_1324 1c353511ff9e855ecf89c7d114625725 174 Gene3D G3DSA:3.40.630.30 1 172 1.6E-38 T 23-10-2018 APE_1324 1c353511ff9e855ecf89c7d114625725 174 Pfam PF00583 Acetyltransferase (GNAT) family 48 140 4.4E-14 T 23-10-2018 IPR000182 GNAT domain APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 Gene3D G3DSA:1.10.455.10 8 205 1.1E-85 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 ProSitePatterns PS00052 Ribosomal protein S7 signature. 71 97 - T 23-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 PIRSF PIRSF002122 8 205 4.6E-48 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 21 205 41.164 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 Pfam PF00177 Ribosomal protein S7p/S5e 64 205 1.8E-41 T 23-10-2018 IPR023798 Ribosomal protein S7 domain APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 SUPERFAMILY SSF47973 22 205 4.58E-65 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily APE_1846.1 9da8a3d052afd81d78ccf333f6381340 205 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 21 205 4.3E-85 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0026 f63bcf0df4a4f1997b4854ac0643fb9c 622 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 291 1.7E-83 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 APE_0026 f63bcf0df4a4f1997b4854ac0643fb9c 622 SUPERFAMILY SSF56059 6 292 4.83E-91 T 23-10-2018 APE_0026 f63bcf0df4a4f1997b4854ac0643fb9c 622 Gene3D G3DSA:3.30.1490.20 2 177 2.2E-60 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APE_0026 f63bcf0df4a4f1997b4854ac0643fb9c 622 Gene3D G3DSA:3.30.470.20 238 298 2.9E-15 T 23-10-2018 APE_0026 f63bcf0df4a4f1997b4854ac0643fb9c 622 Gene3D G3DSA:3.30.470.20 178 237 1.2E-17 T 23-10-2018 APE_2173.1 3e5fe7fd952adfd25cb045fa7fc18ced 217 Pfam PF00687 Ribosomal protein L1p/L10e family 24 209 3.3E-34 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein APE_2173.1 3e5fe7fd952adfd25cb045fa7fc18ced 217 SUPERFAMILY SSF56808 4 213 2.09E-52 T 23-10-2018 IPR023674 Ribosomal protein L1-like APE_2173.1 3e5fe7fd952adfd25cb045fa7fc18ced 217 Gene3D G3DSA:3.40.50.790 62 152 6.1E-59 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich APE_2173.1 3e5fe7fd952adfd25cb045fa7fc18ced 217 PIRSF PIRSF002155 2 216 2.1E-61 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2173.1 3e5fe7fd952adfd25cb045fa7fc18ced 217 Gene3D G3DSA:3.30.190.20 24 210 6.1E-59 T 23-10-2018 APE_2173.1 3e5fe7fd952adfd25cb045fa7fc18ced 217 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 2 214 35.485 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 APE_1059 613a574676c63fc9ff822471e947faab 346 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 8 311 44.395 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 APE_1059 613a574676c63fc9ff822471e947faab 346 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 10 310 2.4E-125 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 APE_1059 613a574676c63fc9ff822471e947faab 346 Gene3D G3DSA:3.20.20.70 7 318 5.6E-104 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1059 613a574676c63fc9ff822471e947faab 346 Pfam PF04055 Radical SAM superfamily 64 239 3.6E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1059 613a574676c63fc9ff822471e947faab 346 Pfam PF08608 Wyosine base formation 251 311 1.3E-19 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 APE_1059 613a574676c63fc9ff822471e947faab 346 SUPERFAMILY SSF102114 65 274 3.92E-12 T 23-10-2018 APE_0449 c1c96a7a87ebb654283029446359e3f4 174 Gene3D G3DSA:3.90.1170.10 1 173 7.2E-74 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 APE_0449 c1c96a7a87ebb654283029446359e3f4 174 Pfam PF00252 Ribosomal protein L16p/L10e 14 165 3.4E-40 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 APE_0449 c1c96a7a87ebb654283029446359e3f4 174 ProSitePatterns PS01257 Ribosomal protein L10e signature. 107 128 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0449 c1c96a7a87ebb654283029446359e3f4 174 SUPERFAMILY SSF54686 4 168 3.14E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 APE_0449 c1c96a7a87ebb654283029446359e3f4 174 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 40.124 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea APE_0449 c1c96a7a87ebb654283029446359e3f4 174 PIRSF PIRSF005590 1 173 8.8E-77 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0182.1 d611900bf5c793797705a15e560d127b 108 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 19 88 8.3E-19 T 23-10-2018 IPR003746 Protein of unknown function DUF167 APE_0182.1 d611900bf5c793797705a15e560d127b 108 SMART SM01152 15 90 2.6E-19 T 23-10-2018 IPR003746 Protein of unknown function DUF167 APE_0182.1 d611900bf5c793797705a15e560d127b 108 Gene3D G3DSA:3.30.1200.10 5 107 1.9E-17 T 23-10-2018 IPR036591 YggU-like superfamily APE_0182.1 d611900bf5c793797705a15e560d127b 108 Hamap MF_00634 UPF0235 protein YggU [yggU]. 15 102 16.059 T 23-10-2018 IPR003746 Protein of unknown function DUF167 APE_0182.1 d611900bf5c793797705a15e560d127b 108 SUPERFAMILY SSF69786 10 103 2.49E-19 T 23-10-2018 IPR036591 YggU-like superfamily APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 SUPERFAMILY SSF54211 3 171 9.87E-36 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 Pfam PF08544 GHMP kinases C terminal 227 302 3.6E-16 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 Gene3D G3DSA:3.30.70.890 180 317 3.3E-31 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 9 289 4.5E-83 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 Pfam PF00288 GHMP kinases N terminal domain 96 162 1.1E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 PRINTS PR00959 Mevalonate kinase family signature 274 291 9.4E-25 T 23-10-2018 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 PRINTS PR00959 Mevalonate kinase family signature 9 33 9.4E-25 T 23-10-2018 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 PRINTS PR00959 Mevalonate kinase family signature 143 162 9.4E-25 T 23-10-2018 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 PRINTS PR00959 Mevalonate kinase family signature 100 122 9.4E-25 T 23-10-2018 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 Hamap MF_00217 Mevalonate kinase [mvk]. 5 319 48.862 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 SUPERFAMILY SSF55060 181 321 9.0E-31 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily APE_2439 bb3c4f17746dc6afedc11b122334e8a0 324 Gene3D G3DSA:3.30.230.10 1 177 8.4E-40 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_2096.1 d55692366285a4c6edf50ca85c86affa 419 Hamap MF_00007 DNA primase DnaG [dnaG]. 1 416 32.064 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 APE_2096.1 d55692366285a4c6edf50ca85c86affa 419 SUPERFAMILY SSF110455 166 263 1.2E-14 T 23-10-2018 APE_2096.1 d55692366285a4c6edf50ca85c86affa 419 SMART SM00493 168 239 4.7E-17 T 23-10-2018 IPR006171 TOPRIM domain APE_2096.1 d55692366285a4c6edf50ca85c86affa 419 Gene3D G3DSA:3.40.1360.10 163 258 8.6E-15 T 23-10-2018 APE_2096.1 d55692366285a4c6edf50ca85c86affa 419 Pfam PF13662 Toprim domain 168 227 2.1E-7 T 23-10-2018 IPR006171 TOPRIM domain APE_0797 129229da66896f69e4366b03e0838d4e 192 SUPERFAMILY SSF75217 1 180 1.12E-19 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_0797 129229da66896f69e4366b03e0838d4e 192 Gene3D G3DSA:3.40.1280.10 1 180 8.8E-23 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APE_0797 129229da66896f69e4366b03e0838d4e 192 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 185 21.911 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 APE_0797 129229da66896f69e4366b03e0838d4e 192 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 186 5.4E-62 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 APE_0228.1 8359019ec3f3ab68f9c472b3b0a5f0bd 272 SUPERFAMILY SSF52166 16 264 7.72E-62 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 APE_0228.1 8359019ec3f3ab68f9c472b3b0a5f0bd 272 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 15 266 42.881 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 APE_0228.1 8359019ec3f3ab68f9c472b3b0a5f0bd 272 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 16 265 2.0E-106 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 APE_0228.1 8359019ec3f3ab68f9c472b3b0a5f0bd 272 Pfam PF00573 Ribosomal protein L4/L1 family 31 264 1.6E-40 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 APE_0228.1 8359019ec3f3ab68f9c472b3b0a5f0bd 272 Gene3D G3DSA:3.40.1370.10 12 270 7.0E-80 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 APE_0228.1 8359019ec3f3ab68f9c472b3b0a5f0bd 272 ProSitePatterns PS00939 Ribosomal protein L1e signature. 118 144 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 Gene3D G3DSA:3.40.50.620 96 414 7.8E-104 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 10 572 32.779 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 SUPERFAMILY SSF50715 415 565 1.88E-23 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 PRINTS PR00987 Glutamyl-tRNA synthetase signature 106 118 2.8E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 PRINTS PR00987 Glutamyl-tRNA synthetase signature 284 294 2.8E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 PRINTS PR00987 Glutamyl-tRNA synthetase signature 135 148 2.8E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 PRINTS PR00987 Glutamyl-tRNA synthetase signature 300 308 2.8E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 PRINTS PR00987 Glutamyl-tRNA synthetase signature 120 131 2.8E-20 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 415 560 7.4E-21 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 103 412 1.9E-70 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 SUPERFAMILY SSF52374 103 421 2.36E-80 T 23-10-2018 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 8 574 5.1E-154 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 Gene3D G3DSA:2.40.240.10 424 515 1.8E-33 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_2317.1 b7289ede3494ad2f88d06ed3a6cca276 574 Gene3D G3DSA:2.40.240.100 415 573 1.8E-33 T 23-10-2018 APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 Gene3D G3DSA:3.50.50.60 4 259 3.8E-92 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 SUPERFAMILY SSF51905 3 251 2.28E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 30 52 3.9E-9 T 23-10-2018 APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 166 181 3.9E-9 T 23-10-2018 APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 8 256 1.3E-67 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 Pfam PF01946 Thi4 family 13 238 3.3E-62 T 23-10-2018 APE_2149.1 e810b0a867839a1f6c56d8042f31f035 270 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 6 257 41.469 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic APE_1891.1 e87e4994e8f129e412a5657e512adf2a 248 Pfam PF00005 ABC transporter 20 169 6.3E-38 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1891.1 e87e4994e8f129e412a5657e512adf2a 248 Gene3D G3DSA:3.40.50.300 1 246 4.9E-80 T 23-10-2018 APE_1891.1 e87e4994e8f129e412a5657e512adf2a 248 SMART SM00382 29 225 2.3E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1891.1 e87e4994e8f129e412a5657e512adf2a 248 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1891.1 e87e4994e8f129e412a5657e512adf2a 248 SUPERFAMILY SSF52540 4 233 3.99E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1301.1 d064bc70d833ba1e9a774cfcbbbcfa37 260 Gene3D G3DSA:3.40.50.300 2 242 7.1E-57 T 23-10-2018 APE_1301.1 d064bc70d833ba1e9a774cfcbbbcfa37 260 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1301.1 d064bc70d833ba1e9a774cfcbbbcfa37 260 SMART SM00382 30 220 2.8E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1301.1 d064bc70d833ba1e9a774cfcbbbcfa37 260 Pfam PF00005 ABC transporter 22 168 1.0E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1301.1 d064bc70d833ba1e9a774cfcbbbcfa37 260 SUPERFAMILY SSF52540 3 239 7.35E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0674.1 2cb5f568ffb556abf46ce2e982aebada 401 SUPERFAMILY SSF53383 6 399 4.44E-98 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_0674.1 2cb5f568ffb556abf46ce2e982aebada 401 Pfam PF00155 Aminotransferase class I and II 33 393 6.2E-50 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APE_0674.1 2cb5f568ffb556abf46ce2e982aebada 401 Gene3D G3DSA:3.40.640.10 6 400 3.9E-99 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 SUPERFAMILY SSF56235 9 495 3.28E-116 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 246 265 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 33 58 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 217 233 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 355 373 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 386 401 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 121 140 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 331 349 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 103 121 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 426 5.0E-33 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 Gene3D G3DSA:3.60.20.40 332 495 1.5E-29 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 Gene3D G3DSA:1.10.246.230 233 331 2.5E-16 T 23-10-2018 APE_0137 21060c3ff6372d32198e9f2d0fb1fc6e 499 Pfam PF01019 Gamma-glutamyltranspeptidase 27 458 4.3E-86 T 23-10-2018 APE_2162.1 0d29220d03298bee842a34fd4e37680f 602 Pfam PF02554 Carbon starvation protein CstA 4 361 1.5E-101 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 APE_2162.1 0d29220d03298bee842a34fd4e37680f 602 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 413 543 4.0E-26 T 23-10-2018 IPR025299 CstA, C-terminal domain APE_0040.1 86960f5cce78da3bee1bd6097d8c2c05 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 277 5.6E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0040.1 86960f5cce78da3bee1bd6097d8c2c05 286 Gene3D G3DSA:1.10.3720.10 8 273 1.8E-56 T 23-10-2018 IPR035906 MetI-like superfamily APE_0040.1 86960f5cce78da3bee1bd6097d8c2c05 286 SUPERFAMILY SSF161098 16 286 5.79E-64 T 23-10-2018 IPR035906 MetI-like superfamily APE_0759.1 8af1aff9ad5b13aee77efff4231e106f 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.8E-5 T 23-10-2018 APE_0759.1 8af1aff9ad5b13aee77efff4231e106f 356 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 3.8E-5 T 23-10-2018 APE_0759.1 8af1aff9ad5b13aee77efff4231e106f 356 Gene3D G3DSA:3.50.50.60 125 345 2.6E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0759.1 8af1aff9ad5b13aee77efff4231e106f 356 Gene3D G3DSA:3.50.50.60 4 119 2.1E-9 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0759.1 8af1aff9ad5b13aee77efff4231e106f 356 SUPERFAMILY SSF51905 6 277 2.6E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 Pfam PF00145 C-5 cytosine-specific DNA methylase 257 316 3.3E-13 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 Pfam PF00145 C-5 cytosine-specific DNA methylase 6 176 4.2E-28 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 Gene3D G3DSA:3.90.120.10 235 305 2.7E-16 T 23-10-2018 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 Gene3D G3DSA:3.40.50.150 1 230 7.2E-46 T 23-10-2018 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 122 136 9.3E-12 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 166 179 9.3E-12 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 6 22 9.3E-12 T 23-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 APE_2002 8a5b9bbeaf395cf9d1ad2a6f2235a9cf 327 SUPERFAMILY SSF53335 5 317 2.34E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0276a c1d622808df54c37ced4b011e24d1965 89 Pfam PF03683 Uncharacterised protein family (UPF0175) 12 81 4.7E-26 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 SUPERFAMILY SSF52540 9 214 3.29E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 Pfam PF13307 Helicase C-terminal domain 438 591 3.8E-22 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 Gene3D G3DSA:3.40.50.300 401 601 4.1E-40 T 23-10-2018 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 SMART SM00488 4 243 2.6E-7 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 SMART SM00491 448 586 3.7E-49 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 Gene3D G3DSA:1.10.275.30 220 345 9.6E-74 T 23-10-2018 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 Gene3D G3DSA:3.40.50.300 14 384 9.6E-74 T 23-10-2018 APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 SUPERFAMILY SSF52540 31 579 1.96E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0322.1 491e4c86b6c8b0dc19ff82e8f6b0dca4 621 Pfam PF06733 DEAD_2 62 227 1.1E-12 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 APE_0404.1 37a19780180f82f88a58558840763f37 463 Gene3D G3DSA:3.40.50.12240 2 461 4.8E-189 T 23-10-2018 APE_0404.1 37a19780180f82f88a58558840763f37 463 SUPERFAMILY SSF52540 81 356 1.49E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0404.1 37a19780180f82f88a58558840763f37 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 352 1.3E-68 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0404.1 37a19780180f82f88a58558840763f37 463 PIRSF PIRSF039114 1 463 3.7E-245 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0404.1 37a19780180f82f88a58558840763f37 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 77 4.4E-12 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_0404.1 37a19780180f82f88a58558840763f37 463 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 7 462 1.5E-262 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 APE_0404.1 37a19780180f82f88a58558840763f37 463 SUPERFAMILY SSF47917 365 419 1.41E-7 T 23-10-2018 APE_0404.1 37a19780180f82f88a58558840763f37 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 5 461 62.649 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0404.1 37a19780180f82f88a58558840763f37 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 343 352 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 APE_1360.1 379ab8c9051c2d802b48ee5b285972a0 173 SUPERFAMILY SSF46785 19 153 7.23E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1360.1 379ab8c9051c2d802b48ee5b285972a0 173 Pfam PF03551 Transcriptional regulator PadR-like family 24 99 6.3E-21 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal APE_1360.1 379ab8c9051c2d802b48ee5b285972a0 173 Gene3D G3DSA:1.10.10.10 10 117 2.0E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0055 84f1cddf0ddbe27adddbe723af9c4cf9 430 Pfam PF03600 Citrate transporter 14 369 6.5E-33 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 APE_0402.1 149a4b843b20a1c54d663477ca281900 211 Pfam PF01813 ATP synthase subunit D 14 203 3.0E-39 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0402.1 149a4b843b20a1c54d663477ca281900 211 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 7 208 7.0E-27 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0402.1 149a4b843b20a1c54d663477ca281900 211 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 5 209 23.041 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0778 cb118480bf2f2c1b314b3706bf3b16ae 329 SMART SM00530 141 196 6.1E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_0778 cb118480bf2f2c1b314b3706bf3b16ae 329 Pfam PF01381 Helix-turn-helix 142 193 3.1E-8 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_0778 cb118480bf2f2c1b314b3706bf3b16ae 329 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 8 318 23.255 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 APE_0778 cb118480bf2f2c1b314b3706bf3b16ae 329 Gene3D G3DSA:1.10.260.40 136 205 3.5E-10 T 23-10-2018 APE_0778 cb118480bf2f2c1b314b3706bf3b16ae 329 SUPERFAMILY SSF47413 138 194 6.19E-11 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 PIRSF PIRSF002134 3 150 1.2E-39 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 ProSitePatterns PS00646 Ribosomal protein S13 signature. 119 132 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 Gene3D G3DSA:4.10.910.10 90 140 1.6E-19 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 SUPERFAMILY SSF46946 11 150 7.51E-34 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 Pfam PF00416 Ribosomal protein S13/S18 12 139 3.1E-43 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 10 150 24.514 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 7 150 1.6E-57 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1737.1 054ae598e7388431e2ab3e3dad6acc12 150 Gene3D G3DSA:1.10.8.50 1 78 9.4E-22 T 23-10-2018 APE_2029.1 6582278ac604a8d23d95d726e7fad1af 360 Pfam PF02277 Phosphoribosyltransferase 88 258 4.9E-12 T 23-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 APE_2029.1 6582278ac604a8d23d95d726e7fad1af 360 SUPERFAMILY SSF52733 39 355 2.09E-48 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 APE_2029.1 6582278ac604a8d23d95d726e7fad1af 360 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 20 351 3.4E-92 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative APE_2029.1 6582278ac604a8d23d95d726e7fad1af 360 Gene3D G3DSA:3.40.50.10210 21 359 3.0E-104 T 23-10-2018 APE_2029.1 6582278ac604a8d23d95d726e7fad1af 360 Hamap MF_01086 UPF0284 protein . 1 360 117.589 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative APE_0092.1 902c2c5d5d72858b723a808b5f6363d9 366 SUPERFAMILY SSF52768 4 316 9.59E-77 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily APE_0092.1 902c2c5d5d72858b723a808b5f6363d9 366 Gene3D G3DSA:3.40.800.20 3 347 2.2E-72 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_0092.1 902c2c5d5d72858b723a808b5f6363d9 366 PRINTS PR01270 Histone deacetylase superfamily signature 126 149 1.6E-9 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_0092.1 902c2c5d5d72858b723a808b5f6363d9 366 PRINTS PR01270 Histone deacetylase superfamily signature 242 252 1.6E-9 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_0092.1 902c2c5d5d72858b723a808b5f6363d9 366 PRINTS PR01270 Histone deacetylase superfamily signature 157 172 1.6E-9 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_0092.1 902c2c5d5d72858b723a808b5f6363d9 366 Pfam PF00850 Histone deacetylase domain 21 295 3.3E-59 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 SMART SM00738 6 90 1.9E-21 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 Gene3D G3DSA:3.30.70.940 9 93 8.9E-23 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 SUPERFAMILY SSF50104 62 149 8.6E-12 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 10 149 7.7E-31 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 Gene3D G3DSA:2.30.30.30 94 151 7.4E-19 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 8 86 1.5E-19 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 SMART SM00739 95 122 1.4E-4 T 23-10-2018 IPR005824 KOW APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 Pfam PF00467 KOW motif 98 128 3.5E-7 T 23-10-2018 IPR005824 KOW APE_2176.1 8bfaaa376a9ed7747cf88a1873a98c89 151 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 8 151 36.89 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 APE_1323.1 34b6c6a476df6094ca4988d5f48a711b 151 SUPERFAMILY SSF50249 4 121 5.61E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1323.1 34b6c6a476df6094ca4988d5f48a711b 151 Pfam PF01336 OB-fold nucleic acid binding domain 18 90 1.2E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 APE_1323.1 34b6c6a476df6094ca4988d5f48a711b 151 Gene3D G3DSA:2.40.50.140 5 120 4.0E-30 T 23-10-2018 APE_0959 4b867d54d17209bae6a8eb20b05a1bb2 175 SUPERFAMILY SSF46767 60 136 6.28E-23 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 APE_0959 4b867d54d17209bae6a8eb20b05a1bb2 175 Gene3D G3DSA:1.10.10.10 58 138 1.1E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0959 4b867d54d17209bae6a8eb20b05a1bb2 175 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 61 135 8.3E-26 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 APE_0959 4b867d54d17209bae6a8eb20b05a1bb2 175 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 61 133 1.3E-20 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 APE_0959 4b867d54d17209bae6a8eb20b05a1bb2 175 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 103 109 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 APE_0275.1 b162ef93579392b514eb871a06f4a0f8 133 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 2 128 2.6E-5 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 APE_0275.1 b162ef93579392b514eb871a06f4a0f8 133 SUPERFAMILY SSF48150 2 124 1.66E-21 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APE_0275.1 b162ef93579392b514eb871a06f4a0f8 133 Gene3D G3DSA:1.10.340.30 1 104 4.5E-20 T 23-10-2018 APE_2090 499221c688ef3d86a7a664af01d0708e 208 ProSitePatterns PS01331 Thymidylate kinase signature. 90 102 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 APE_2090 499221c688ef3d86a7a664af01d0708e 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 4 165 3.2E-34 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 APE_2090 499221c688ef3d86a7a664af01d0708e 208 Pfam PF02223 Thymidylate kinase 6 168 7.6E-35 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 APE_2090 499221c688ef3d86a7a664af01d0708e 208 SUPERFAMILY SSF52540 1 175 2.98E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2090 499221c688ef3d86a7a664af01d0708e 208 Hamap MF_00165 Thymidylate kinase [tmk]. 2 203 17.851 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 APE_2090 499221c688ef3d86a7a664af01d0708e 208 Gene3D G3DSA:3.40.50.300 1 204 1.6E-41 T 23-10-2018 APE_1056.1 25eb3418b707043905eef166b662d1b6 231 Gene3D G3DSA:3.30.700.20 19 210 3.6E-61 T 23-10-2018 IPR027485 AMMECR1, N-terminal APE_1056.1 25eb3418b707043905eef166b662d1b6 231 Hamap MF_00645 Protein . 21 201 35.638 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 APE_1056.1 25eb3418b707043905eef166b662d1b6 231 Pfam PF01871 AMMECR1 29 202 1.4E-47 T 23-10-2018 IPR002733 AMMECR1 domain APE_1056.1 25eb3418b707043905eef166b662d1b6 231 SUPERFAMILY SSF143447 19 221 4.91E-62 T 23-10-2018 IPR036071 AMMECR1 domain superfamily APE_1056.1 25eb3418b707043905eef166b662d1b6 231 Gene3D G3DSA:3.30.1490.150 126 199 3.6E-61 T 23-10-2018 APE_1056.1 25eb3418b707043905eef166b662d1b6 231 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 23 213 2.0E-50 T 23-10-2018 IPR023473 AMMECR1 APE_1056.1 25eb3418b707043905eef166b662d1b6 231 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 27 203 1.6E-49 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A APE_0859 ff3fdbae16f84ba7abaab4d2aa745b89 168 SUPERFAMILY SSF50494 18 137 3.38E-5 T 23-10-2018 IPR009003 Peptidase S1, PA clan APE_1958.1 11b6fe8597035a5bf5ecfab12c3614a8 286 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 16 270 48.318 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 APE_1958.1 11b6fe8597035a5bf5ecfab12c3614a8 286 SUPERFAMILY SSF52402 12 268 1.26E-70 T 23-10-2018 APE_1958.1 11b6fe8597035a5bf5ecfab12c3614a8 286 TIGRFAM TIGR00552 nadE: NAD+ synthetase 20 269 6.6E-71 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 APE_1958.1 11b6fe8597035a5bf5ecfab12c3614a8 286 Gene3D G3DSA:3.40.50.620 20 278 1.7E-76 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1958.1 11b6fe8597035a5bf5ecfab12c3614a8 286 Pfam PF02540 NAD synthase 22 267 6.5E-74 T 23-10-2018 IPR022310 NAD/GMP synthase APE_1178 ea4af573809a85d9341ca3290158e7bc 187 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 9 178 1.0E-61 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 APE_1178 ea4af573809a85d9341ca3290158e7bc 187 SUPERFAMILY SSF51182 6 186 8.02E-68 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily APE_1178 ea4af573809a85d9341ca3290158e7bc 187 Gene3D G3DSA:2.60.120.10 5 186 4.7E-65 T 23-10-2018 IPR014710 RmlC-like jelly roll fold APE_1178 ea4af573809a85d9341ca3290158e7bc 187 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 7 180 1.2E-75 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 APE_1178 ea4af573809a85d9341ca3290158e7bc 187 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 6 179 3.0E-98 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 APE_1800.1 3c57292f2d98887b142add355fa94010 356 SUPERFAMILY SSF159065 6 121 3.27E-25 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain APE_1800.1 3c57292f2d98887b142add355fa94010 356 SUPERFAMILY SSF53137 127 245 3.05E-13 T 23-10-2018 APE_1800.1 3c57292f2d98887b142add355fa94010 356 Gene3D G3DSA:2.30.30.870 1 126 2.0E-41 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain APE_1800.1 3c57292f2d98887b142add355fa94010 356 Gene3D G3DSA:3.30.420.60 127 248 2.2E-28 T 23-10-2018 APE_1800.1 3c57292f2d98887b142add355fa94010 356 Hamap MF_01853 Protein pelota homolog [pelA]. 2 349 31.043 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 APE_1800.1 3c57292f2d98887b142add355fa94010 356 SUPERFAMILY SSF55315 242 349 3.47E-24 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1800.1 3c57292f2d98887b142add355fa94010 356 SMART SM01194 1 125 3.4E-33 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like APE_1800.1 3c57292f2d98887b142add355fa94010 356 Pfam PF03465 eRF1 domain 3 251 349 2.1E-21 T 23-10-2018 IPR005142 eRF1 domain 3 APE_1800.1 3c57292f2d98887b142add355fa94010 356 Gene3D G3DSA:3.30.1330.30 249 356 3.5E-36 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like APE_1800.1 3c57292f2d98887b142add355fa94010 356 Pfam PF03463 eRF1 domain 1 7 121 3.1E-17 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like APE_0230.1 dbd3516ff9c13a49162168e507114e27 309 SUPERFAMILY SSF52540 47 301 6.5E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0230.1 dbd3516ff9c13a49162168e507114e27 309 Gene3D G3DSA:3.40.50.300 28 290 1.6E-74 T 23-10-2018 APE_0230.1 dbd3516ff9c13a49162168e507114e27 309 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 44 290 1.3E-86 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 APE_0230.1 dbd3516ff9c13a49162168e507114e27 309 ProSitePatterns PS01215 Mrp family signature. 154 170 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 APE_0230.1 dbd3516ff9c13a49162168e507114e27 309 Hamap MF_02040 Iron-sulfur cluster carrier protein. 39 291 33.695 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein APE_1335.1 80bea6b1cbcc493ec475ef8bc5a1e9a0 341 Gene3D G3DSA:3.40.630.10 9 333 4.2E-100 T 23-10-2018 APE_1335.1 80bea6b1cbcc493ec475ef8bc5a1e9a0 341 Gene3D G3DSA:2.40.30.40 66 160 4.2E-100 T 23-10-2018 IPR023367 Peptidase M42, domain 2 APE_1335.1 80bea6b1cbcc493ec475ef8bc5a1e9a0 341 SUPERFAMILY SSF53187 3 336 2.17E-57 T 23-10-2018 APE_1335.1 80bea6b1cbcc493ec475ef8bc5a1e9a0 341 Pfam PF05343 M42 glutamyl aminopeptidase 44 332 1.2E-88 T 23-10-2018 IPR008007 Peptidase M42 APE_1335.1 80bea6b1cbcc493ec475ef8bc5a1e9a0 341 PIRSF PIRSF001123 2 341 2.3E-115 T 23-10-2018 IPR008007 Peptidase M42 APE_1335.1 80bea6b1cbcc493ec475ef8bc5a1e9a0 341 SUPERFAMILY SSF101821 67 178 1.24E-23 T 23-10-2018 APE_0025.1 ccf84ea3c3dd6c5e0b62be89e16663f3 135 SUPERFAMILY SSF46785 4 93 5.54E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0025.1 ccf84ea3c3dd6c5e0b62be89e16663f3 135 Gene3D G3DSA:1.10.10.10 1 100 3.2E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0025.1 ccf84ea3c3dd6c5e0b62be89e16663f3 135 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 2.2E-27 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal APE_0308.1 73e632632efbc0011dc289e3b4c65553 476 Pfam PF01565 FAD binding domain 63 198 4.1E-31 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 APE_0308.1 73e632632efbc0011dc289e3b4c65553 476 SUPERFAMILY SSF55103 215 466 4.09E-27 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 APE_0308.1 73e632632efbc0011dc289e3b4c65553 476 SUPERFAMILY SSF56176 42 239 3.22E-37 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APE_0308.1 73e632632efbc0011dc289e3b4c65553 476 Pfam PF02913 FAD linked oxidases, C-terminal domain 286 465 9.6E-21 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 APE_0308.1 73e632632efbc0011dc289e3b4c65553 476 Gene3D G3DSA:3.30.465.40 54 248 9.1E-48 T 23-10-2018 APE_0308.1 73e632632efbc0011dc289e3b4c65553 476 Gene3D G3DSA:3.40.462.40 283 425 1.9E-17 T 23-10-2018 APE_2486.1 0f02ce53056139c3f64d7fc0caec9cb1 253 PIRSF PIRSF017269 2 253 1.2E-71 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 APE_2486.1 0f02ce53056139c3f64d7fc0caec9cb1 253 SUPERFAMILY SSF53335 12 248 2.03E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_2486.1 0f02ce53056139c3f64d7fc0caec9cb1 253 Gene3D G3DSA:3.40.50.150 65 253 4.5E-46 T 23-10-2018 APE_2486.1 0f02ce53056139c3f64d7fc0caec9cb1 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 60 206 4.8E-21 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 APE_2486.1 0f02ce53056139c3f64d7fc0caec9cb1 253 Gene3D G3DSA:3.10.330.20 5 56 1.3E-5 T 23-10-2018 APE_2389 8b67c52dc438d242ed4c94daa3478c43 181 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 46 78 8.5E-11 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal APE_2389 8b67c52dc438d242ed4c94daa3478c43 181 SUPERFAMILY SSF50249 25 166 2.06E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_2389 8b67c52dc438d242ed4c94daa3478c43 181 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 82 161 9.0E-12 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal APE_2389 8b67c52dc438d242ed4c94daa3478c43 181 Gene3D G3DSA:1.10.12.20 15 85 1.2E-25 T 23-10-2018 APE_2257 2bdce713d50ce179b4103ec6e772c6d5 515 PIRSF PIRSF002741 26 513 6.9E-97 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 APE_2257 2bdce713d50ce179b4103ec6e772c6d5 515 Gene3D G3DSA:3.40.190.10 27 266 6.1E-61 T 23-10-2018 APE_2257 2bdce713d50ce179b4103ec6e772c6d5 515 SUPERFAMILY SSF53850 32 514 3.8E-131 T 23-10-2018 APE_2257 2bdce713d50ce179b4103ec6e772c6d5 515 Gene3D G3DSA:3.10.105.10 271 487 1.3E-66 T 23-10-2018 APE_2257 2bdce713d50ce179b4103ec6e772c6d5 515 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 77 437 2.2E-89 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain APE_0374 96c9329fc958ada22702dd07a9769259 1064 SUPERFAMILY SSF47323 653 905 5.05E-51 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_0374 96c9329fc958ada22702dd07a9769259 1064 Gene3D G3DSA:1.10.730.10 646 834 1.6E-46 T 23-10-2018 APE_0374 96c9329fc958ada22702dd07a9769259 1064 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 400 415 1.5E-28 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APE_0374 96c9329fc958ada22702dd07a9769259 1064 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 46 57 1.5E-28 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APE_0374 96c9329fc958ada22702dd07a9769259 1064 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 227 250 1.5E-28 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APE_0374 96c9329fc958ada22702dd07a9769259 1064 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 562 571 1.5E-28 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APE_0374 96c9329fc958ada22702dd07a9769259 1064 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 523 536 1.5E-28 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APE_0374 96c9329fc958ada22702dd07a9769259 1064 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 24 642 4.8E-178 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_0374 96c9329fc958ada22702dd07a9769259 1064 SUPERFAMILY SSF47323 970 1056 1.18E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_0374 96c9329fc958ada22702dd07a9769259 1064 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 16 850 2.6E-278 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 APE_0374 96c9329fc958ada22702dd07a9769259 1064 Pfam PF08264 Anticodon-binding domain of tRNA 690 843 7.8E-29 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APE_0374 96c9329fc958ada22702dd07a9769259 1064 SUPERFAMILY SSF50677 206 402 3.98E-52 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APE_0374 96c9329fc958ada22702dd07a9769259 1064 SUPERFAMILY SSF52374 11 647 1.21E-131 T 23-10-2018 APE_0374 96c9329fc958ada22702dd07a9769259 1064 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 5 1055 13.272 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_0374 96c9329fc958ada22702dd07a9769259 1064 Gene3D G3DSA:3.90.740.10 203 406 3.0E-221 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APE_0374 96c9329fc958ada22702dd07a9769259 1064 Gene3D G3DSA:3.40.50.620 22 629 3.0E-221 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0771.1 1d60756f16623f37f0a7fa45ffda1ec4 384 Pfam PF04123 Domain of unknown function (DUF373) 22 351 1.9E-71 T 23-10-2018 IPR007254 Protein of unknown function DUF373 APE_2001.1 b90c9a5a4fe313e4af7d17e5f3c0b1cf 156 Pfam PF09895 RecB-family nuclease (DUF2122) 40 145 3.1E-32 T 23-10-2018 IPR018665 Protein of unknown function DUF2122, RecB-family nuclease-related APE_2616 0611d9f5e74e71668e436b0d6164ef73 141 SUPERFAMILY SSF88723 1 130 2.72E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_2616 0611d9f5e74e71668e436b0d6164ef73 141 Pfam PF01850 PIN domain 1 120 1.3E-15 T 23-10-2018 IPR002716 PIN domain APE_2616 0611d9f5e74e71668e436b0d6164ef73 141 Gene3D G3DSA:3.40.50.1010 1 127 2.8E-12 T 23-10-2018 APE_1782.1 047adcdf0fdd4c7f117350568bf88813 245 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 15 243 61.601 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 APE_1782.1 047adcdf0fdd4c7f117350568bf88813 245 SUPERFAMILY SSF52467 4 241 2.38E-84 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APE_1782.1 047adcdf0fdd4c7f117350568bf88813 245 Gene3D G3DSA:3.30.1600.10 31 163 2.8E-87 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily APE_1782.1 047adcdf0fdd4c7f117350568bf88813 245 Gene3D G3DSA:3.40.50.1220 13 235 2.8E-87 T 23-10-2018 APE_1782.1 047adcdf0fdd4c7f117350568bf88813 245 Pfam PF02146 Sir2 family 22 193 4.5E-56 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 APE_0028 a22ead8af0ea36ad6ac08f310a96d9e9 218 SUPERFAMILY SSF52009 108 217 3.14E-32 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 APE_0028 a22ead8af0ea36ad6ac08f310a96d9e9 218 Gene3D G3DSA:3.50.30.10 114 218 4.8E-37 T 23-10-2018 APE_0028 a22ead8af0ea36ad6ac08f310a96d9e9 218 Pfam PF00391 PEP-utilising enzyme, mobile domain 142 213 1.5E-24 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 APE_0954 f305ddb9a5fb00daebf7f0b7a4a080db 237 SUPERFAMILY SSF102215 8 200 4.18E-42 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 APE_0954 f305ddb9a5fb00daebf7f0b7a4a080db 237 Pfam PF02633 Creatinine amidohydrolase 17 167 5.3E-37 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 APE_0954 f305ddb9a5fb00daebf7f0b7a4a080db 237 Gene3D G3DSA:3.40.50.10310 18 174 2.9E-38 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 APE_0088.1 65eb6ed52cf8fdd7407809b052187c27 323 SMART SM00966 15 60 7.3E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0088.1 65eb6ed52cf8fdd7407809b052187c27 323 SUPERFAMILY SSF89447 18 58 1.01E-5 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily APE_0088.1 65eb6ed52cf8fdd7407809b052187c27 323 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 17 55 6.2E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_2473.1 96149c8dee9cb303a07aae42b8f52701 237 SUPERFAMILY SSF56300 4 218 4.29E-21 T 23-10-2018 APE_2473.1 96149c8dee9cb303a07aae42b8f52701 237 Gene3D G3DSA:3.60.21.10 5 217 1.4E-7 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_2473.1 96149c8dee9cb303a07aae42b8f52701 237 Pfam PF00149 Calcineurin-like phosphoesterase 4 199 5.4E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APE_1792 edc2a33b01447bc07855d27a4540db27 176 Pfam PF02834 LigT like Phosphoesterase 83 162 1.4E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX APE_1792 edc2a33b01447bc07855d27a4540db27 176 Pfam PF02834 LigT like Phosphoesterase 4 77 1.0E-16 T 23-10-2018 IPR014051 Phosphoesterase, HXTX APE_1792 edc2a33b01447bc07855d27a4540db27 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 5 169 1.6E-45 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 APE_1792 edc2a33b01447bc07855d27a4540db27 176 SUPERFAMILY SSF55144 3 168 9.42E-42 T 23-10-2018 IPR009097 Cyclic phosphodiesterase APE_1792 edc2a33b01447bc07855d27a4540db27 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 6 170 21.643 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 APE_1792 edc2a33b01447bc07855d27a4540db27 176 Gene3D G3DSA:3.90.1140.10 1 170 3.0E-47 T 23-10-2018 APE_0246.1 3f4f6eb1629920c67b39a29a8ad0fc3c 353 ProSitePatterns PS01235 PdxS/SNZ family signature. 260 278 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0246.1 3f4f6eb1629920c67b39a29a8ad0fc3c 353 Pfam PF01680 SOR/SNZ family 62 267 2.2E-96 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0246.1 3f4f6eb1629920c67b39a29a8ad0fc3c 353 SUPERFAMILY SSF51366 73 322 1.69E-56 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_0246.1 3f4f6eb1629920c67b39a29a8ad0fc3c 353 PIRSF PIRSF029271 51 351 1.3E-141 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0246.1 3f4f6eb1629920c67b39a29a8ad0fc3c 353 Gene3D G3DSA:3.20.20.70 55 345 2.2E-123 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0246.1 3f4f6eb1629920c67b39a29a8ad0fc3c 353 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 59 351 49.163 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0636 5dd8df6baae517e5c862ab587ce15282 250 Gene3D G3DSA:3.60.15.10 4 250 7.4E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0636 5dd8df6baae517e5c862ab587ce15282 250 Pfam PF12706 Beta-lactamase superfamily domain 33 219 1.8E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0636 5dd8df6baae517e5c862ab587ce15282 250 SMART SM00849 20 200 1.5E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0636 5dd8df6baae517e5c862ab587ce15282 250 SUPERFAMILY SSF56281 5 247 4.87E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1557.1 75119c1a9e0a74b351c9e7b7604cbd0d 312 SMART SM00829 12 310 6.0E-9 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 APE_1557.1 75119c1a9e0a74b351c9e7b7604cbd0d 312 Gene3D G3DSA:3.90.180.10 5 312 8.8E-70 T 23-10-2018 APE_1557.1 75119c1a9e0a74b351c9e7b7604cbd0d 312 Pfam PF00107 Zinc-binding dehydrogenase 156 276 1.2E-18 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 APE_1557.1 75119c1a9e0a74b351c9e7b7604cbd0d 312 SUPERFAMILY SSF51735 119 283 2.02E-32 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1557.1 75119c1a9e0a74b351c9e7b7604cbd0d 312 SUPERFAMILY SSF50129 6 150 2.67E-26 T 23-10-2018 IPR011032 GroES-like superfamily APE_1557.1 75119c1a9e0a74b351c9e7b7604cbd0d 312 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 114 2.0E-8 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 APE_0047.1 529c61aa32ead5ef1112120cc6d153b3 310 Gene3D G3DSA:1.10.3720.10 63 307 5.3E-22 T 23-10-2018 IPR035906 MetI-like superfamily APE_0047.1 529c61aa32ead5ef1112120cc6d153b3 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 302 1.0E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0047.1 529c61aa32ead5ef1112120cc6d153b3 310 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 12 306 4.6E-75 T 23-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 APE_0047.1 529c61aa32ead5ef1112120cc6d153b3 310 SUPERFAMILY SSF161098 26 298 1.06E-23 T 23-10-2018 IPR035906 MetI-like superfamily APE_1087b 2d00e0acea6c1a451462bbcc1baf352f 115 Gene3D G3DSA:1.10.8.140 29 115 3.6E-23 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 APE_1087b 2d00e0acea6c1a451462bbcc1baf352f 115 Pfam PF01984 Double-stranded DNA-binding domain 12 115 3.3E-22 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 APE_1087b 2d00e0acea6c1a451462bbcc1baf352f 115 PIRSF PIRSF015730 3 115 2.1E-30 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 APE_1087b 2d00e0acea6c1a451462bbcc1baf352f 115 SUPERFAMILY SSF46950 12 112 9.59E-26 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 APE_1087b 2d00e0acea6c1a451462bbcc1baf352f 115 Hamap MF_00026 DNA-binding protein . 7 114 16.124 T 23-10-2018 IPR022889 DNA-binding protein, archaeal APE_0818.1 2f293a345efc54192dce4e24ad8db17d 413 SUPERFAMILY SSF56349 136 386 3.24E-13 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 APE_0818.1 2f293a345efc54192dce4e24ad8db17d 413 Gene3D G3DSA:1.10.443.10 227 405 9.7E-12 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APE_0818.1 2f293a345efc54192dce4e24ad8db17d 413 Pfam PF00589 Phage integrase family 228 385 4.4E-6 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 APE_0252 c36ef6e593181ce04ea570c3fad30f0d 392 SUPERFAMILY SSF102114 30 341 9.03E-42 T 23-10-2018 APE_0252 c36ef6e593181ce04ea570c3fad30f0d 392 PIRSF PIRSF004762 1 392 6.0E-130 T 23-10-2018 APE_0252 c36ef6e593181ce04ea570c3fad30f0d 392 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 65 376 2.1E-94 T 23-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 APE_0252 c36ef6e593181ce04ea570c3fad30f0d 392 Pfam PF04055 Radical SAM superfamily 74 236 1.0E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_0252 c36ef6e593181ce04ea570c3fad30f0d 392 Gene3D G3DSA:3.20.20.70 11 362 3.0E-43 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0252 c36ef6e593181ce04ea570c3fad30f0d 392 SMART SM00729 67 284 0.0013 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_2550 c77071cf91cbefe0d0ad02bf70004318 252 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 246 23.559 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2550 c77071cf91cbefe0d0ad02bf70004318 252 Pfam PF00290 Tryptophan synthase alpha chain 5 230 3.1E-23 T 23-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2550 c77071cf91cbefe0d0ad02bf70004318 252 SUPERFAMILY SSF51366 5 238 1.7E-43 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_2550 c77071cf91cbefe0d0ad02bf70004318 252 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 36 49 - T 23-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 APE_2550 c77071cf91cbefe0d0ad02bf70004318 252 Gene3D G3DSA:3.20.20.70 2 248 3.0E-41 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0156.1 c5063136778a22b29e0c52dbacec9879 386 SUPERFAMILY SSF161093 223 384 6.02E-15 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 APE_0156.1 c5063136778a22b29e0c52dbacec9879 386 SUPERFAMILY SSF161093 28 181 3.14E-7 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 APE_0156.1 c5063136778a22b29e0c52dbacec9879 386 Pfam PF01769 Divalent cation transporter 253 376 5.4E-11 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 APE_2524.1 0f3553f0cf3af5abf0225009f59bc94c 239 Gene3D G3DSA:3.40.50.300 2 237 2.1E-59 T 23-10-2018 APE_2524.1 0f3553f0cf3af5abf0225009f59bc94c 239 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 236 1.2E-8 T 23-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal APE_2524.1 0f3553f0cf3af5abf0225009f59bc94c 239 SUPERFAMILY SSF52540 4 235 4.13E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2524.1 0f3553f0cf3af5abf0225009f59bc94c 239 SMART SM00382 29 222 2.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2524.1 0f3553f0cf3af5abf0225009f59bc94c 239 Pfam PF00005 ABC transporter 20 164 5.0E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2352.1 122c35d99111511f31b6f5fa6fc24821 317 Pfam PF02754 Cysteine-rich domain 210 292 3.5E-8 T 23-10-2018 IPR004017 Cysteine-rich domain APE_1117 f8fbde5a346859dfe56270098a917dfb 242 SMART SM00849 8 199 1.0E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_1117 f8fbde5a346859dfe56270098a917dfb 242 SUPERFAMILY SSF56281 3 237 7.34E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1117 f8fbde5a346859dfe56270098a917dfb 242 Pfam PF13483 Beta-lactamase superfamily domain 3 199 1.1E-23 T 23-10-2018 APE_1117 f8fbde5a346859dfe56270098a917dfb 242 Gene3D G3DSA:3.60.15.10 2 237 6.2E-62 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1117 f8fbde5a346859dfe56270098a917dfb 242 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 237 36.894 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 APE_2121.1 9ff77147ce64e576066f50efc7cdf039 520 Gene3D G3DSA:3.40.640.10 91 358 1.2E-53 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2121.1 9ff77147ce64e576066f50efc7cdf039 520 SUPERFAMILY SSF53383 13 497 2.33E-101 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2121.1 9ff77147ce64e576066f50efc7cdf039 520 Gene3D G3DSA:3.90.1150.10 359 490 1.6E-28 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2121.1 9ff77147ce64e576066f50efc7cdf039 520 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 505 56.877 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 APE_1365.1 2cc535d22df93d986b86d3aa54878624 241 Hamap MF_00608 GTP cyclohydrolase III [gch3]. 9 239 37.347 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 APE_1365.1 2cc535d22df93d986b86d3aa54878624 241 Pfam PF05165 GTP cyclohydrolase III 10 241 3.3E-98 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 APE_1365.1 2cc535d22df93d986b86d3aa54878624 241 Gene3D G3DSA:3.30.70.270 125 239 1.5E-28 T 23-10-2018 APE_1365.1 2cc535d22df93d986b86d3aa54878624 241 ProDom PD313320 GTP III HYDROLASE CYCLOHYDROLASE RIBOFLAVIN BIOSYNTHESIS 3.5.4.- FAMILY MAGNESIUM GGDN 15 228 7.0E-101 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 APE_1365.1 2cc535d22df93d986b86d3aa54878624 241 Gene3D G3DSA:3.30.70.1230 6 124 3.4E-26 T 23-10-2018 IPR029787 Nucleotide cyclase APE_1365.1 2cc535d22df93d986b86d3aa54878624 241 PIRSF PIRSF009265 6 241 8.4E-76 T 23-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 APE_0342.1 1f5e22e85fd793d822cef2d954c1ce79 349 Pfam PF03061 Thioesterase superfamily 202 266 2.1E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 APE_0342.1 1f5e22e85fd793d822cef2d954c1ce79 349 Gene3D G3DSA:3.10.129.10 172 330 8.6E-23 T 23-10-2018 APE_0342.1 1f5e22e85fd793d822cef2d954c1ce79 349 Gene3D G3DSA:3.10.129.10 4 164 1.8E-21 T 23-10-2018 APE_0342.1 1f5e22e85fd793d822cef2d954c1ce79 349 SUPERFAMILY SSF54637 8 161 7.48E-21 T 23-10-2018 IPR029069 HotDog domain superfamily APE_0342.1 1f5e22e85fd793d822cef2d954c1ce79 349 SUPERFAMILY SSF54637 182 324 3.06E-23 T 23-10-2018 IPR029069 HotDog domain superfamily APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 231 247 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 SUPERFAMILY SSF51735 104 292 9.4E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 Gene3D G3DSA:3.40.50.720 99 292 1.3E-131 T 23-10-2018 APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 324 9.1E-40 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 Hamap MF_00776 Glyoxylate reductase [gyaR]. 2 333 62.32 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 202 224 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 292 6.6E-68 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 Gene3D G3DSA:3.40.50.720 5 319 1.3E-131 T 23-10-2018 APE_1831.1 5b81c51836dc9032b694b2ea1bf1bb38 335 SUPERFAMILY SSF52283 3 135 9.64E-38 T 23-10-2018 APE_0454 e1792b61c9c1c65b4139f86e2242d93a 240 Gene3D G3DSA:3.40.1350.60 82 224 5.9E-28 T 23-10-2018 APE_0454 e1792b61c9c1c65b4139f86e2242d93a 240 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 2 233 37.855 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein APE_0454 e1792b61c9c1c65b4139f86e2242d93a 240 Gene3D G3DSA:2.40.50.580 3 80 1.3E-11 T 23-10-2018 APE_0454 e1792b61c9c1c65b4139f86e2242d93a 240 Pfam PF03749 Sugar fermentation stimulation protein 14 214 2.4E-41 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 SUPERFAMILY SSF48163 330 535 1.83E-32 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 3 534 3.9E-92 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 Pfam PF01921 tRNA synthetases class I (K) 4 369 2.4E-109 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 Gene3D G3DSA:3.40.50.620 5 276 2.7E-69 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 Gene3D G3DSA:2.30.30.300 177 222 2.7E-69 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 SUPERFAMILY SSF52374 5 326 2.45E-36 T 23-10-2018 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 3 536 33.366 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 Gene3D G3DSA:1.10.10.770 327 441 2.5E-23 T 23-10-2018 APE_0161.1 10bf12c902fe4508179c10e5073364d5 545 Gene3D G3DSA:1.10.10.350 442 535 4.0E-15 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 5.6E-13 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 5.6E-13 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 5.6E-13 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 5.6E-13 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 Pfam PF00701 Dihydrodipicolinate synthetase family 5 288 9.9E-49 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 Gene3D G3DSA:3.20.20.70 4 292 6.7E-67 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 SUPERFAMILY SSF51569 6 289 3.35E-60 T 23-10-2018 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 SMART SM01130 3 294 9.5E-60 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_1023.1 1c5e722ec7bb60238603c81c08f01406 303 PIRSF PIRSF001365 2 301 2.3E-74 T 23-10-2018 IPR002220 DapA-like GO:0016829 APE_2430.1 b8b8c751bd97a0e1656e5c6aafdd5901 159 SUPERFAMILY SSF52833 38 145 5.47E-26 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_2430.1 b8b8c751bd97a0e1656e5c6aafdd5901 159 Gene3D G3DSA:3.40.30.10 32 148 2.4E-22 T 23-10-2018 APE_2430.1 b8b8c751bd97a0e1656e5c6aafdd5901 159 Pfam PF00085 Thioredoxin 46 142 3.5E-17 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 APE_1623 9f7a66214f25e6802621461b5f795140 548 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 216 270 - T 23-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 285 306 3.3E-13 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 414 435 3.3E-13 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 214 235 3.3E-13 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 51 74 3.3E-13 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 PRINTS PR01165 Cytochrome c oxidase subunit I signature 117 129 3.3E-13 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 Gene3D G3DSA:1.20.210.10 6 544 1.6E-126 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 SUPERFAMILY SSF81442 13 541 4.32E-107 T 23-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1623 9f7a66214f25e6802621461b5f795140 548 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 15 462 6.2E-86 T 23-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 471 9.4E-150 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 Gene3D G3DSA:3.40.50.620 1 303 1.8E-132 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 Gene3D G3DSA:1.20.120.640 304 472 3.0E-21 T 23-10-2018 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 SUPERFAMILY SSF52374 3 311 1.9E-94 T 23-10-2018 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 5.3E-31 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 5.3E-31 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 5.3E-31 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 5.3E-31 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 SUPERFAMILY SSF47323 341 471 2.75E-22 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 472 34.907 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 APE_1592.1 50e5ad9cc89baff080e04f9d9cc92e9f 472 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 309 5.4E-124 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 APE_1558b 1121a268b332b7488f9a11f615f58768 94 SUPERFAMILY SSF143011 3 85 5.23E-18 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily APE_1558b 1121a268b332b7488f9a11f615f58768 94 Gene3D G3DSA:3.30.2310.20 2 88 7.0E-19 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily APE_1558b 1121a268b332b7488f9a11f615f58768 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 86 5.7E-12 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family APE_0254 086f1a77c517881ae2571e53a1f0dd86 235 Pfam PF02621 Menaquinone biosynthesis 19 179 1.6E-7 T 23-10-2018 IPR003773 Menaquinone biosynthesis enzyme APE_0254 086f1a77c517881ae2571e53a1f0dd86 235 SUPERFAMILY SSF53850 19 232 2.99E-27 T 23-10-2018 APE_0254 086f1a77c517881ae2571e53a1f0dd86 235 Gene3D G3DSA:3.40.190.10 68 186 1.3E-13 T 23-10-2018 APE_0254 086f1a77c517881ae2571e53a1f0dd86 235 Gene3D G3DSA:3.40.190.10 14 211 1.3E-13 T 23-10-2018 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Gene3D G3DSA:2.70.20.10 212 468 2.4E-91 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 2 618 3.5E-302 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Pfam PF01751 Toprim domain 1 132 6.1E-8 T 23-10-2018 IPR006171 TOPRIM domain APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 301 315 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Gene3D G3DSA:1.10.290.10 272 399 2.4E-91 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 SMART SM00436 124 218 2.5E-17 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 484 498 8.1E-18 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 385 401 8.1E-18 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 306 315 8.1E-18 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 188 206 8.1E-18 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 98 111 8.1E-18 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Pfam PF01131 DNA topoisomerase 149 558 3.9E-103 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Gene3D G3DSA:3.40.50.140 1 147 5.5E-16 T 23-10-2018 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 SMART SM00437 264 520 1.8E-62 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 658 42.71 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 Gene3D G3DSA:1.10.460.10 155 567 2.4E-91 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 APE_1794 4e52d6c9a190bb70b159f7698c30367b 673 SUPERFAMILY SSF56712 1 602 5.1E-120 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain APE_1209a 19a19372989708c68a9ab636e9b48cc5 65 Gene3D G3DSA:1.10.540.10 13 64 2.1E-7 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APE_1209a 19a19372989708c68a9ab636e9b48cc5 65 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 55 7.1E-6 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 APE_1209a 19a19372989708c68a9ab636e9b48cc5 65 SUPERFAMILY SSF56645 16 57 3.81E-6 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APE_1493 27000644d13944b099ea46d24be2f373 240 SUPERFAMILY SSF69618 23 233 1.44E-20 T 23-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_1493 27000644d13944b099ea46d24be2f373 240 Gene3D G3DSA:3.40.50.10090 44 156 1.9E-9 T 23-10-2018 APE_1493 27000644d13944b099ea46d24be2f373 240 Pfam PF02602 Uroporphyrinogen-III synthase HemD 26 226 1.3E-14 T 23-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 APE_0462 56a6d52377abffa5d19b0ee7678f90e7 513 Pfam PF00437 Type II/IV secretion system protein 214 373 2.0E-10 T 23-10-2018 IPR001482 Type II/IV secretion system protein APE_0462 56a6d52377abffa5d19b0ee7678f90e7 513 SMART SM00670 8 117 5.9E-8 T 23-10-2018 IPR002716 PIN domain APE_0462 56a6d52377abffa5d19b0ee7678f90e7 513 SUPERFAMILY SSF52540 139 439 1.26E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0462 56a6d52377abffa5d19b0ee7678f90e7 513 Gene3D G3DSA:3.40.50.300 241 443 8.7E-22 T 23-10-2018 APE_0462 56a6d52377abffa5d19b0ee7678f90e7 513 SMART SM00382 259 484 0.0019 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0462 56a6d52377abffa5d19b0ee7678f90e7 513 Gene3D G3DSA:3.40.50.1010 7 132 2.1E-17 T 23-10-2018 APE_1281 a6bc45eeb8a8ead7c30e56b9873b0e87 643 SMART SM00471 57 279 5.2E-6 T 23-10-2018 IPR003607 HD/PDEase domain APE_1281 a6bc45eeb8a8ead7c30e56b9873b0e87 643 SUPERFAMILY SSF109604 10 384 1.42E-56 T 23-10-2018 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 Gene3D G3DSA:3.10.440.10 4 89 1.2E-23 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 SUPERFAMILY SSF54575 6 81 4.45E-23 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 SMART SM01380 6 84 9.5E-24 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 2 91 21.379 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 ProSitePatterns PS01144 Ribosomal protein L31e signature. 45 59 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 Pfam PF01198 Ribosomal protein L31e 6 81 2.3E-17 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1087.1 326ae9d9c543c1fe520a59f4f62eabcd 104 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 6 55 4.0E-13 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0595.1 5116dc788b3a0a50ba441248ea747d8c 383 SUPERFAMILY SSF51905 4 315 1.2E-23 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0595.1 5116dc788b3a0a50ba441248ea747d8c 383 SUPERFAMILY SSF51905 117 246 5.76E-21 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0595.1 5116dc788b3a0a50ba441248ea747d8c 383 Gene3D G3DSA:3.50.50.60 5 313 2.5E-70 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0595.1 5116dc788b3a0a50ba441248ea747d8c 383 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 288 4.8E-18 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_0595.1 5116dc788b3a0a50ba441248ea747d8c 383 Gene3D G3DSA:3.50.50.60 113 255 2.5E-70 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0124 1d9ac2b0ec252882644ba87694a017b2 332 SUPERFAMILY SSF64182 6 305 7.95E-32 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily APE_0124 1d9ac2b0ec252882644ba87694a017b2 332 Pfam PF02272 DHHA1 domain 169 294 1.1E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 APE_0124 1d9ac2b0ec252882644ba87694a017b2 332 Gene3D G3DSA:3.10.310.30 240 304 3.9E-10 T 23-10-2018 APE_0951.1 53739555fab31f6c0499e6ffd638464c 143 Pfam PF01597 Glycine cleavage H-protein 21 139 2.1E-47 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate APE_0951.1 53739555fab31f6c0499e6ffd638464c 143 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 18 139 41.723 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 APE_0951.1 53739555fab31f6c0499e6ffd638464c 143 Gene3D G3DSA:2.40.50.100 12 140 1.9E-51 T 23-10-2018 APE_0951.1 53739555fab31f6c0499e6ffd638464c 143 SUPERFAMILY SSF51230 18 139 1.29E-45 T 23-10-2018 IPR011053 Single hybrid motif APE_0951.1 53739555fab31f6c0499e6ffd638464c 143 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 61 90 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APE_0951.1 53739555fab31f6c0499e6ffd638464c 143 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 19 138 4.6E-44 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 APE_1275b 4374496d8bf8fc8938a3be61e3901d33 98 Gene3D G3DSA:3.60.21.10 5 74 2.1E-15 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_1275b 4374496d8bf8fc8938a3be61e3901d33 98 SUPERFAMILY SSF56300 12 68 5.22E-15 T 23-10-2018 APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 Gene3D G3DSA:3.10.400.10 1 163 1.1E-44 T 23-10-2018 APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 Gene3D G3DSA:3.40.50.620 170 377 4.6E-88 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 Pfam PF01747 ATP-sulfurylase 169 376 1.0E-85 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 Pfam PF14306 PUA-like domain 4 161 1.9E-48 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 SUPERFAMILY SSF88697 4 165 7.66E-46 T 23-10-2018 IPR015947 PUA-like superfamily APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 376 1.2E-112 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 381 51.826 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 APE_1197.1 25a5b3387a0751c714ce72854e0d8265 383 SUPERFAMILY SSF52374 169 378 5.33E-78 T 23-10-2018 APE_0964.1 d1b6d636ec42fe78f65ade272c833b0d 289 SUPERFAMILY SSF53335 115 280 4.18E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0964.1 d1b6d636ec42fe78f65ade272c833b0d 289 Gene3D G3DSA:3.40.50.150 121 277 1.1E-21 T 23-10-2018 APE_0964.1 d1b6d636ec42fe78f65ade272c833b0d 289 Pfam PF03602 Conserved hypothetical protein 95 136 220 2.7E-6 T 23-10-2018 APE_1457 772bfb738a6fad3aafb661d2f0ead17a 173 Gene3D G3DSA:1.20.1260.10 7 161 1.6E-42 T 23-10-2018 IPR012347 Ferritin-like APE_1457 772bfb738a6fad3aafb661d2f0ead17a 173 SUPERFAMILY SSF47240 15 162 1.57E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily APE_1457 772bfb738a6fad3aafb661d2f0ead17a 173 PIRSF PIRSF018063 1 169 2.5E-59 T 23-10-2018 IPR014490 DNA-binding protein from starved cells-like APE_1457 772bfb738a6fad3aafb661d2f0ead17a 173 Pfam PF00210 Ferritin-like domain 19 162 2.6E-30 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 APE_0689.1 abd4754fe279bd1c00c66803ed66eaa1 432 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 35 413 1.2E-97 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APE_0689.1 abd4754fe279bd1c00c66803ed66eaa1 432 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 304 323 - T 23-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 APE_0689.1 abd4754fe279bd1c00c66803ed66eaa1 432 SUPERFAMILY SSF53659 11 418 5.4E-125 T 23-10-2018 APE_0689.1 abd4754fe279bd1c00c66803ed66eaa1 432 SMART SM01329 34 414 9.3E-155 T 23-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 APE_0689.1 abd4754fe279bd1c00c66803ed66eaa1 432 Gene3D G3DSA:3.40.718.10 1 432 2.9E-183 T 23-10-2018 APE_0216.1 60846776df67b36768ab701744b7f813 189 Gene3D G3DSA:3.40.50.150 9 175 5.8E-25 T 23-10-2018 APE_0216.1 60846776df67b36768ab701744b7f813 189 Pfam PF08241 Methyltransferase domain 50 144 2.3E-14 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APE_0216.1 60846776df67b36768ab701744b7f813 189 SUPERFAMILY SSF53335 14 143 4.78E-24 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1940.1 ff340db585746b5f0f0c73f6ff197499 212 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 21 211 3.2E-66 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 APE_1940.1 ff340db585746b5f0f0c73f6ff197499 212 Gene3D G3DSA:3.40.50.10490 16 211 1.6E-53 T 23-10-2018 APE_1940.1 ff340db585746b5f0f0c73f6ff197499 212 Pfam PF01380 SIS domain 51 151 4.1E-18 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 APE_1940.1 ff340db585746b5f0f0c73f6ff197499 212 SUPERFAMILY SSF53697 15 211 8.6E-41 T 23-10-2018 APE_2254.1 3fc6b09bf6be208d443e40fc8473f1d9 575 Gene3D G3DSA:3.40.190.10 99 553 3.0E-38 T 23-10-2018 APE_2254.1 3fc6b09bf6be208d443e40fc8473f1d9 575 Pfam PF01547 Bacterial extracellular solute-binding protein 107 481 1.7E-54 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein APE_2254.1 3fc6b09bf6be208d443e40fc8473f1d9 575 SUPERFAMILY SSF53850 137 552 9.51E-36 T 23-10-2018 APE_0438.1 4aea7c64c8f497e85f924a532c7ba994 342 SUPERFAMILY SSF56747 12 326 2.4E-69 T 23-10-2018 APE_0438.1 4aea7c64c8f497e85f924a532c7ba994 342 Hamap MF_00700 DNA primase small subunit PriS [priS]. 8 322 27.642 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 APE_0438.1 4aea7c64c8f497e85f924a532c7ba994 342 Gene3D G3DSA:3.90.920.30 10 330 6.1E-74 T 23-10-2018 APE_0438.1 4aea7c64c8f497e85f924a532c7ba994 342 Pfam PF01896 DNA primase small subunit 96 262 7.2E-23 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 APE_1491.1 7d6b06532291a1f0c750bbbbcea67202 220 Gene3D G3DSA:3.40.50.720 3 132 1.1E-22 T 23-10-2018 APE_1491.1 7d6b06532291a1f0c750bbbbcea67202 220 SUPERFAMILY SSF51735 1 112 7.43E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1491.1 7d6b06532291a1f0c750bbbbcea67202 220 Pfam PF13241 Putative NAD(P)-binding 7 116 6.9E-20 T 23-10-2018 APE_1491.1 7d6b06532291a1f0c750bbbbcea67202 220 SUPERFAMILY SSF75615 120 204 1.19E-5 T 23-10-2018 APE_0656a 761dca09de2cd6bd809e135ea56cf0b7 83 Gene3D G3DSA:3.30.70.920 2 74 9.0E-22 T 23-10-2018 APE_0656a 761dca09de2cd6bd809e135ea56cf0b7 83 Pfam PF01037 Lrp/AsnC ligand binding domain 6 75 7.9E-13 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain APE_0656a 761dca09de2cd6bd809e135ea56cf0b7 83 SUPERFAMILY SSF54909 3 76 1.11E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 5 223 1.0E-75 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 SUPERFAMILY SSF52402 3 225 1.84E-54 T 23-10-2018 APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 Gene3D G3DSA:3.40.50.620 1 128 1.7E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 3 206 7.7E-45 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 Gene3D G3DSA:3.90.1490.10 130 227 1.0E-17 T 23-10-2018 APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 Pfam PF01902 Diphthamide synthase 3 206 2.6E-47 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_0421 b2563e75e2162e4f953d9e320c0af5ff 238 PIRSF PIRSF039123 1 238 5.2E-73 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 Pfam PF01497 Periplasmic binding protein 184 420 1.4E-30 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 Gene3D G3DSA:1.20.5.340 99 162 4.4E-7 T 23-10-2018 APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 SUPERFAMILY SSF57997 31 162 7.85E-13 T 23-10-2018 APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 Gene3D G3DSA:3.40.50.1980 163 293 3.5E-32 T 23-10-2018 APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 SUPERFAMILY SSF53807 161 443 2.08E-52 T 23-10-2018 APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 Gene3D G3DSA:3.40.50.1980 316 447 5.0E-25 T 23-10-2018 APE_1049.1 57a8256e09f3dd587b8a735b5fe70f95 490 Gene3D G3DSA:1.20.5.340 26 98 5.5E-5 T 23-10-2018 APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 Gene3D G3DSA:3.40.50.300 6 332 2.8E-92 T 23-10-2018 APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 SUPERFAMILY SSF52540 25 262 6.93E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 Pfam PF00005 ABC transporter 39 191 2.6E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 SMART SM00382 47 241 1.0E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 325 1.7E-25 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_2263.1 aeb5c2be692168e4eca924925681e89b 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 3.1E-17 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1297 4ffcde60cb5e59db7b153fabe1fccd24 321 Pfam PF09459 Ethylbenzene dehydrogenase 52 248 9.6E-39 T 23-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 APE_1297 4ffcde60cb5e59db7b153fabe1fccd24 321 SMART SM00887 52 248 2.5E-49 T 23-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 APE_1297 4ffcde60cb5e59db7b153fabe1fccd24 321 Gene3D G3DSA:2.60.40.1190 37 258 1.7E-41 T 23-10-2018 APE_1297 4ffcde60cb5e59db7b153fabe1fccd24 321 TIGRFAM TIGR03477 DMSO_red_II_gam: DMSO reductase family type II enzyme, heme b subunit 38 257 4.4E-81 T 23-10-2018 IPR017838 DMSO reductase family, type II, haem b-binding subunit GO:0020037|GO:0042597 APE_0558.1 a4637330bd98f31a9219c93183e96781 431 Gene3D G3DSA:3.40.50.2300 167 298 6.8E-46 T 23-10-2018 APE_0558.1 a4637330bd98f31a9219c93183e96781 431 Pfam PF13458 Periplasmic binding protein 44 407 5.0E-37 T 23-10-2018 IPR028081 Leucine-binding protein domain APE_0558.1 a4637330bd98f31a9219c93183e96781 431 SUPERFAMILY SSF53822 43 428 4.48E-47 T 23-10-2018 IPR028082 Periplasmic binding protein-like I APE_0558.1 a4637330bd98f31a9219c93183e96781 431 Gene3D G3DSA:3.40.50.2300 54 388 6.8E-46 T 23-10-2018 APE_1512 062cf204e2a7e4cc68b24403e324be5b 307 SUPERFAMILY SSF54211 62 136 5.53E-5 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_1512 062cf204e2a7e4cc68b24403e324be5b 307 PIRSF PIRSF004884 1 303 1.7E-89 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 APE_1512 062cf204e2a7e4cc68b24403e324be5b 307 Pfam PF08544 GHMP kinases C terminal 201 277 1.1E-5 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain APE_1892 ccf2ae8e76828c4018f1353e1c6c8e07 220 Gene3D G3DSA:1.10.3720.10 2 212 4.9E-49 T 23-10-2018 IPR035906 MetI-like superfamily APE_1892 ccf2ae8e76828c4018f1353e1c6c8e07 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 210 1.0E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1892 ccf2ae8e76828c4018f1353e1c6c8e07 220 SUPERFAMILY SSF161098 10 200 3.14E-41 T 23-10-2018 IPR035906 MetI-like superfamily APE_1892 ccf2ae8e76828c4018f1353e1c6c8e07 220 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 105 1.3E-28 T 23-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 APE_2004.1 aedda350871390ba75151e40be8fe919 189 PIRSF PIRSF006373 14 187 7.2E-35 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 APE_2004.1 aedda350871390ba75151e40be8fe919 189 Pfam PF08271 TFIIB zinc-binding 128 166 1.1E-8 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type APE_2004.1 aedda350871390ba75151e40be8fe919 189 SMART SM00531 32 170 3.8E-63 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 APE_2004.1 aedda350871390ba75151e40be8fe919 189 SUPERFAMILY SSF57783 117 161 1.36E-5 T 23-10-2018 APE_2004.1 aedda350871390ba75151e40be8fe919 189 SUPERFAMILY SSF46785 23 101 6.97E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2004.1 aedda350871390ba75151e40be8fe919 189 Pfam PF02002 TFIIE alpha subunit 44 115 2.1E-8 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 APE_2004.1 aedda350871390ba75151e40be8fe919 189 Gene3D G3DSA:1.10.10.10 17 101 3.7E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2004.1 aedda350871390ba75151e40be8fe919 189 Hamap MF_01909 Transcription factor E [tfe]. 7 178 21.902 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 Gene3D G3DSA:3.30.1430.10 82 192 6.8E-115 T 23-10-2018 APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 SUPERFAMILY SSF50447 4 343 1.06E-89 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 8 341 1.8E-142 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 342 49.686 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 ProSitePatterns PS00474 Ribosomal protein L3 signature. 197 220 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 Gene3D G3DSA:2.40.30.10 43 320 6.8E-115 T 23-10-2018 APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 Pfam PF00297 Ribosomal protein L3 4 343 2.0E-79 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0227 7071866a245b6cc0ff7b6ecd410785db 344 Gene3D G3DSA:4.10.960.10 9 259 6.8E-115 T 23-10-2018 APE_1588a b0aaf1e9c9517e59940149da8fe0ce68 77 Gene3D G3DSA:3.30.1490.20 1 76 2.7E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APE_1588a b0aaf1e9c9517e59940149da8fe0ce68 77 SUPERFAMILY SSF56059 3 76 3.06E-23 T 23-10-2018 APE_1588a b0aaf1e9c9517e59940149da8fe0ce68 77 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 3 76 1.1E-27 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 APE_0586.1 89c6c1b233e3792fe31c6208bfb83f9c 236 Gene3D G3DSA:3.40.50.970 12 236 7.1E-50 T 23-10-2018 APE_0586.1 89c6c1b233e3792fe31c6208bfb83f9c 236 SUPERFAMILY SSF52518 24 231 9.91E-44 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_0586.1 89c6c1b233e3792fe31c6208bfb83f9c 236 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 60 234 6.6E-20 T 23-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 APE_0683 56d409e11d6aa527768014919567649e 222 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 180 1.1E-13 T 23-10-2018 APE_0683 56d409e11d6aa527768014919567649e 222 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 2 202 1.7E-97 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal APE_0683 56d409e11d6aa527768014919567649e 222 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 182 1.8E-22 T 23-10-2018 APE_0683 56d409e11d6aa527768014919567649e 222 Gene3D G3DSA:3.40.50.1000 1 209 3.6E-39 T 23-10-2018 IPR023214 HAD superfamily APE_0683 56d409e11d6aa527768014919567649e 222 SUPERFAMILY SSF56784 3 210 4.07E-31 T 23-10-2018 IPR036412 HAD-like superfamily APE_0304.1 d14f31f33203579cc0f0368194568802 799 SMART SM00089 163 260 1.1E-18 T 23-10-2018 IPR022409 PKD/Chitinase domain APE_0304.1 d14f31f33203579cc0f0368194568802 799 SMART SM00089 70 150 6.1E-15 T 23-10-2018 IPR022409 PKD/Chitinase domain APE_0304.1 d14f31f33203579cc0f0368194568802 799 Gene3D G3DSA:3.10.105.10 542 773 3.5E-133 T 23-10-2018 APE_0304.1 d14f31f33203579cc0f0368194568802 799 Gene3D G3DSA:3.40.190.10 462 786 3.5E-133 T 23-10-2018 APE_0304.1 d14f31f33203579cc0f0368194568802 799 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 321 343 - T 23-10-2018 IPR023765 Solute-binding protein family 5, conserved site APE_0304.1 d14f31f33203579cc0f0368194568802 799 Pfam PF00801 PKD domain 70 138 1.6E-14 T 23-10-2018 IPR000601 PKD domain APE_0304.1 d14f31f33203579cc0f0368194568802 799 Pfam PF00801 PKD domain 175 246 1.9E-11 T 23-10-2018 IPR000601 PKD domain APE_0304.1 d14f31f33203579cc0f0368194568802 799 Gene3D G3DSA:2.60.40.10 156 257 1.2E-20 T 23-10-2018 IPR013783 Immunoglobulin-like fold APE_0304.1 d14f31f33203579cc0f0368194568802 799 Gene3D G3DSA:2.60.40.10 58 149 1.8E-21 T 23-10-2018 IPR013783 Immunoglobulin-like fold APE_0304.1 d14f31f33203579cc0f0368194568802 799 SUPERFAMILY SSF49299 62 148 3.27E-19 T 23-10-2018 IPR035986 PKD domain superfamily APE_0304.1 d14f31f33203579cc0f0368194568802 799 Gene3D G3DSA:3.90.76.10 287 461 3.5E-133 T 23-10-2018 APE_0304.1 d14f31f33203579cc0f0368194568802 799 SUPERFAMILY SSF53850 269 796 2.53E-122 T 23-10-2018 APE_0304.1 d14f31f33203579cc0f0368194568802 799 SUPERFAMILY SSF49299 160 259 1.24E-17 T 23-10-2018 IPR035986 PKD domain superfamily APE_0304.1 d14f31f33203579cc0f0368194568802 799 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 315 710 5.1E-94 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain APE_1445 70f4c2f073981df0378cf9decd8b6ff8 276 SUPERFAMILY SSF54211 16 220 7.09E-51 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_1445 70f4c2f073981df0378cf9decd8b6ff8 276 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 7 273 44.284 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 APE_1445 70f4c2f073981df0378cf9decd8b6ff8 276 Gene3D G3DSA:3.30.230.70 13 275 2.8E-75 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1445 70f4c2f073981df0378cf9decd8b6ff8 276 SUPERFAMILY SSF55666 192 275 5.24E-21 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1445 70f4c2f073981df0378cf9decd8b6ff8 276 Pfam PF03725 3' exoribonuclease family, domain 2 198 258 1.7E-11 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_1445 70f4c2f073981df0378cf9decd8b6ff8 276 Pfam PF01138 3' exoribonuclease family, domain 1 38 171 8.6E-31 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 APE_2455.1 25d7c1c489c81034573784e9f906153f 286 Pfam PF00924 Mechanosensitive ion channel 72 265 9.5E-8 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 Gene3D G3DSA:3.30.559.10 160 410 9.0E-89 T 23-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 Pfam PF00364 Biotin-requiring enzyme 6 78 4.4E-19 T 23-10-2018 IPR000089 Biotin/lipoyl attachment APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 Gene3D G3DSA:4.10.320.10 119 159 3.8E-16 T 23-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 SUPERFAMILY SSF47005 119 158 1.44E-10 T 23-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 176 405 5.6E-85 T 23-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 SUPERFAMILY SSF51230 4 97 4.71E-25 T 23-10-2018 IPR011053 Single hybrid motif APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 SUPERFAMILY SSF52777 166 405 4.89E-82 T 23-10-2018 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 Gene3D G3DSA:2.40.50.100 1 87 6.3E-24 T 23-10-2018 APE_1671 477dc7671df45f652c3ad24f3aa713ab 412 Pfam PF02817 e3 binding domain 120 155 2.0E-13 T 23-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 APE_0517 d51db33699da2104905c5d51a6fe5f38 268 Gene3D G3DSA:3.10.50.80 4 163 1.2E-42 T 23-10-2018 APE_0517 d51db33699da2104905c5d51a6fe5f38 268 SUPERFAMILY SSF54534 4 153 8.04E-34 T 23-10-2018 APE_0517 d51db33699da2104905c5d51a6fe5f38 268 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 5 100 6.9E-9 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain APE_0427.1 40f92cfaa1af232d883086679a0bb9b1 227 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 16 185 1.6E-74 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 APE_0427.1 40f92cfaa1af232d883086679a0bb9b1 227 Pfam PF03167 Uracil DNA glycosylase superfamily 30 173 3.5E-42 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APE_0427.1 40f92cfaa1af232d883086679a0bb9b1 227 Gene3D G3DSA:3.40.470.10 4 191 5.7E-65 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APE_0427.1 40f92cfaa1af232d883086679a0bb9b1 227 SMART SM00987 30 184 1.5E-37 T 23-10-2018 APE_0427.1 40f92cfaa1af232d883086679a0bb9b1 227 SUPERFAMILY SSF52141 5 183 3.92E-56 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APE_0427.1 40f92cfaa1af232d883086679a0bb9b1 227 SMART SM00986 30 184 1.5E-37 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 Gene3D G3DSA:3.40.50.300 257 492 1.1E-36 T 23-10-2018 APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 Gene3D G3DSA:3.40.50.300 3 240 5.7E-58 T 23-10-2018 APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 ProSitePatterns PS00211 ABC transporters family signature. 401 415 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 SUPERFAMILY SSF52540 262 483 2.62E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 SMART SM00382 38 223 1.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 Pfam PF00005 ABC transporter 279 428 2.5E-11 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 SUPERFAMILY SSF52540 13 226 5.79E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2588 b68a9cbbbc4cf2c612d79f2401b1c6ce 498 Pfam PF00005 ABC transporter 29 175 2.4E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1850 527431651d20e5a897cffdf8a3ef6683 144 SUPERFAMILY SSF54814 15 75 1.77E-11 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APE_1850 527431651d20e5a897cffdf8a3ef6683 144 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 6 143 2.2E-41 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal APE_1850 527431651d20e5a897cffdf8a3ef6683 144 SMART SM00322 34 126 0.0013 T 23-10-2018 IPR004087 K Homology domain GO:0003676 APE_1850 527431651d20e5a897cffdf8a3ef6683 144 SUPERFAMILY SSF54814 77 138 6.21E-9 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 APE_1850 527431651d20e5a897cffdf8a3ef6683 144 Gene3D G3DSA:3.30.300.20 1 75 2.2E-33 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta APE_1850 527431651d20e5a897cffdf8a3ef6683 144 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 3 144 28.828 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal APE_1850 527431651d20e5a897cffdf8a3ef6683 144 Gene3D G3DSA:3.30.300.20 76 144 5.0E-25 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta APE_1850 527431651d20e5a897cffdf8a3ef6683 144 Pfam PF07650 KH domain 14 98 6.3E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1850 527431651d20e5a897cffdf8a3ef6683 144 Pfam PF07650 KH domain 103 137 1.1E-5 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0549.1 8b09e89f57681c6463dc6d2c8965ba32 113 SUPERFAMILY SSF47819 3 99 3.27E-20 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 APE_0549.1 8b09e89f57681c6463dc6d2c8965ba32 113 PIRSF PIRSF005053 1 112 3.5E-34 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) APE_0549.1 8b09e89f57681c6463dc6d2c8965ba32 113 Gene3D G3DSA:1.10.150.80 48 111 6.0E-8 T 23-10-2018 APE_1954 ed6e401b2e5a153536b427d80acca943 191 SUPERFAMILY SSF55729 10 190 1.33E-36 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_1954 ed6e401b2e5a153536b427d80acca943 191 Pfam PF00583 Acetyltransferase (GNAT) family 37 167 5.9E-21 T 23-10-2018 IPR000182 GNAT domain APE_1954 ed6e401b2e5a153536b427d80acca943 191 Gene3D G3DSA:3.40.630.30 11 191 3.8E-52 T 23-10-2018 APE_2039.1 3a704ceededb21ab2a7172e7b173f929 320 Pfam PF03186 CobD/Cbib protein 20 280 3.4E-60 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 APE_2039.1 3a704ceededb21ab2a7172e7b173f929 320 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 319 52.566 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 APE_0579 719f5b9b45e784222ce01c51687dad0e 358 Gene3D G3DSA:3.40.50.1970 4 171 1.1E-38 T 23-10-2018 APE_0579 719f5b9b45e784222ce01c51687dad0e 358 SUPERFAMILY SSF56796 24 348 2.36E-69 T 23-10-2018 APE_0579 719f5b9b45e784222ce01c51687dad0e 358 Pfam PF01761 3-dehydroquinate synthase 71 321 2.6E-70 T 23-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 APE_0579 719f5b9b45e784222ce01c51687dad0e 358 PIRSF PIRSF001455 3 357 3.4E-102 T 23-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 APE_0579 719f5b9b45e784222ce01c51687dad0e 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 26 349 6.6E-95 T 23-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 APE_0579 719f5b9b45e784222ce01c51687dad0e 358 Gene3D G3DSA:1.20.1090.10 174 353 2.7E-39 T 23-10-2018 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 1 438 35.235 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Pfam PF02881 SRP54-type protein, helical bundle domain 3 78 8.2E-15 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 SMART SM00963 1 82 5.2E-18 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Pfam PF02978 Signal peptide binding domain 324 424 8.7E-28 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 SMART SM00962 96 292 1.8E-90 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 SMART SM00382 95 297 1.2E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Gene3D G3DSA:3.40.50.300 86 281 6.5E-102 T 23-10-2018 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Pfam PF00448 SRP54-type protein, GTPase domain 98 292 5.8E-64 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 SUPERFAMILY SSF47446 324 427 5.07E-30 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Gene3D G3DSA:1.20.120.140 5 301 6.5E-102 T 23-10-2018 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 Gene3D G3DSA:1.10.260.30 305 439 6.3E-38 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 APE_1735 31eb6c51751b17cb3236467b414c98ca 441 SUPERFAMILY SSF52540 39 350 1.06E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 SUPERFAMILY SSF52374 100 203 6.22E-17 T 23-10-2018 APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 SUPERFAMILY SSF158372 8 91 2.49E-16 T 23-10-2018 IPR036809 AF1782-like superfamily APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 Gene3D G3DSA:1.20.1270.90 5 90 1.4E-18 T 23-10-2018 APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 Pfam PF04010 Protein of unknown function (DUF357) 14 89 2.3E-18 T 23-10-2018 IPR023140 Domain of unknown function DUF357 APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 Gene3D G3DSA:3.40.50.620 100 218 1.1E-27 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 Pfam PF01467 Cytidylyltransferase-like 105 196 4.2E-11 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APE_2281.1 b5f5f3d5878602e62bf17ac60256e416 246 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 102 164 2.5E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 Gene3D G3DSA:3.10.580.10 160 302 4.8E-14 T 23-10-2018 APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 SUPERFAMILY SSF54631 179 299 1.72E-17 T 23-10-2018 APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 Gene3D G3DSA:1.10.3080.10 1 159 2.6E-28 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 Pfam PF00571 CBS domain 253 300 0.0019 T 23-10-2018 IPR000644 CBS domain APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 Pfam PF00571 CBS domain 191 230 3.5E-6 T 23-10-2018 IPR000644 CBS domain APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 SUPERFAMILY SSF81340 2 155 8.5E-28 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 SMART SM00116 252 300 1.3 T 23-10-2018 IPR000644 CBS domain APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 SMART SM00116 188 235 15.0 T 23-10-2018 IPR000644 CBS domain APE_1552 49e67b8e1bc961d44f807c3b9357dfac 319 Pfam PF00654 Voltage gated chloride channel 3 143 2.8E-21 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APE_0279.1 297b998177adf0a0464052aa9ee6af2f 152 Pfam PF01850 PIN domain 7 126 1.6E-6 T 23-10-2018 IPR002716 PIN domain APE_0279.1 297b998177adf0a0464052aa9ee6af2f 152 SUPERFAMILY SSF88723 6 133 3.64E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0279.1 297b998177adf0a0464052aa9ee6af2f 152 Gene3D G3DSA:3.40.50.1010 5 130 3.5E-13 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SUPERFAMILY SSF54631 391 447 3.25E-8 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SUPERFAMILY SSF54631 1 124 1.36E-15 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Gene3D G3DSA:3.10.580.10 2 129 9.4E-14 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Gene3D G3DSA:3.10.580.10 281 377 7.0E-11 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 74 124 0.0095 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 464 511 5.6 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 554 602 6.2E-11 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 328 376 0.029 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 10 61 5.8 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 219 268 9.5E-7 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SMART SM00116 399 447 1.9 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Gene3D G3DSA:3.10.580.10 131 267 1.9E-15 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Gene3D G3DSA:3.10.580.10 541 629 9.8E-13 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SUPERFAMILY SSF54631 455 601 1.42E-22 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Gene3D G3DSA:3.10.580.10 383 515 3.2E-16 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 SUPERFAMILY SSF54631 211 375 5.91E-26 T 23-10-2018 APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Pfam PF00571 CBS domain 322 375 1.3E-7 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Pfam PF00571 CBS domain 212 267 8.9E-10 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Pfam PF00571 CBS domain 6 58 0.0038 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Pfam PF00571 CBS domain 74 123 3.3E-7 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Pfam PF00571 CBS domain 556 602 3.5E-13 T 23-10-2018 IPR000644 CBS domain APE_0785.1 12963bbb1208911eee2f7f6d7391cee2 630 Pfam PF00571 CBS domain 395 446 4.9E-8 T 23-10-2018 IPR000644 CBS domain APE_0675.1 d0509dde4e9ea5c6061fc90b8eb94871 116 Pfam PF01588 Putative tRNA binding domain 20 113 2.3E-31 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 APE_0675.1 d0509dde4e9ea5c6061fc90b8eb94871 116 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 10 116 1.1E-40 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 APE_0675.1 d0509dde4e9ea5c6061fc90b8eb94871 116 Gene3D G3DSA:2.40.50.140 7 116 1.1E-37 T 23-10-2018 APE_0675.1 d0509dde4e9ea5c6061fc90b8eb94871 116 SUPERFAMILY SSF50249 13 115 4.41E-34 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1084a ad492422b40391391e960b4df30a6fa2 88 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 22 47 3.0E-8 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 APE_1084a ad492422b40391391e960b4df30a6fa2 88 Gene3D G3DSA:3.10.20.10 4 82 3.4E-25 T 23-10-2018 APE_1084a ad492422b40391391e960b4df30a6fa2 88 SUPERFAMILY SSF160374 3 79 1.44E-22 T 23-10-2018 APE_1084a ad492422b40391391e960b4df30a6fa2 88 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 4 63 22.329 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1084a ad492422b40391391e960b4df30a6fa2 88 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 13 63 1.0E-12 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 210 231 9.9E-17 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 83 99 9.9E-17 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 256 266 9.9E-17 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 135 154 9.9E-17 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 70 370 3.2E-95 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 SUPERFAMILY SSF52374 6 360 3.9E-70 T 23-10-2018 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 Gene3D G3DSA:3.40.50.620 1 256 6.7E-71 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 Gene3D G3DSA:1.10.240.10 257 372 3.5E-47 T 23-10-2018 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 Pfam PF00579 tRNA synthetases class I (W and Y) 69 349 7.0E-41 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2461.1 088eb485a62cc23eeec528a48ac52ba9 372 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 368 45.935 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 APE_1350.1 1f49f1f6c481e092afbc673468278a85 146 Gene3D G3DSA:3.30.70.640 1 146 2.3E-54 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_1350.1 1f49f1f6c481e092afbc673468278a85 146 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 139 2.5E-57 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_1350.1 1f49f1f6c481e092afbc673468278a85 146 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 1 146 36.871 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 APE_1350.1 1f49f1f6c481e092afbc673468278a85 146 Pfam PF01967 MoaC family 6 146 2.8E-45 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_1350.1 1f49f1f6c481e092afbc673468278a85 146 SUPERFAMILY SSF55040 4 146 1.83E-43 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0278 71b5538dd4e85d72f480402f95b667a6 158 Pfam PF10130 PIN domain 13 118 8.5E-15 T 23-10-2018 IPR002716 PIN domain APE_0278 71b5538dd4e85d72f480402f95b667a6 158 SMART SM00670 10 136 3.1E-13 T 23-10-2018 IPR002716 PIN domain APE_0278 71b5538dd4e85d72f480402f95b667a6 158 Gene3D G3DSA:3.40.50.1010 7 140 2.4E-5 T 23-10-2018 APE_0278 71b5538dd4e85d72f480402f95b667a6 158 SUPERFAMILY SSF88723 12 134 7.57E-9 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_1724.1 690f1c262858c396dbe92539460adcf3 265 SUPERFAMILY SSF50022 115 238 4.77E-22 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APE_1724.1 690f1c262858c396dbe92539460adcf3 265 Pfam PF00355 Rieske [2Fe-2S] domain 133 212 5.6E-12 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APE_1724.1 690f1c262858c396dbe92539460adcf3 265 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 7 31 2.5E-5 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal APE_2545.1 e5e79cff2221207c098e4d723b5be519 369 Gene3D G3DSA:3.40.190.10 148 285 5.2E-31 T 23-10-2018 APE_2545.1 e5e79cff2221207c098e4d723b5be519 369 Pfam PF16868 NMT1-like family 64 358 2.0E-17 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family APE_2545.1 e5e79cff2221207c098e4d723b5be519 369 Gene3D G3DSA:3.40.190.10 64 358 5.2E-31 T 23-10-2018 APE_2545.1 e5e79cff2221207c098e4d723b5be519 369 SUPERFAMILY SSF53850 60 361 2.99E-30 T 23-10-2018 APE_1535.1 2a24a7f084be7d3838cebcb419e2e92a 365 Pfam PF13353 4Fe-4S single cluster domain 146 235 5.0E-6 T 23-10-2018 APE_1535.1 2a24a7f084be7d3838cebcb419e2e92a 365 PIRSF PIRSF004869 77 362 3.0E-60 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted APE_1535.1 2a24a7f084be7d3838cebcb419e2e92a 365 Gene3D G3DSA:3.20.20.70 144 358 3.8E-12 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1535.1 2a24a7f084be7d3838cebcb419e2e92a 365 SUPERFAMILY SSF102114 150 351 7.32E-20 T 23-10-2018 APE_1535.1 2a24a7f084be7d3838cebcb419e2e92a 365 Pfam PF04055 Radical SAM superfamily 147 295 4.2E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_2617c 7088524fa9d9a0aa470969a9a04a33cc 72 Pfam PF01954 Protein of unknown function DUF104 2 64 3.0E-18 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_2617c 7088524fa9d9a0aa470969a9a04a33cc 72 SUPERFAMILY SSF141694 2 52 5.75E-11 T 23-10-2018 APE_2617c 7088524fa9d9a0aa470969a9a04a33cc 72 Gene3D G3DSA:4.10.1150.10 1 65 2.5E-9 T 23-10-2018 IPR024069 AF2212-like domain superfamily APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 Gene3D G3DSA:3.40.50.10470 171 370 6.6E-66 T 23-10-2018 APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 Pfam PF01008 Initiation factor 2 subunit family 64 358 1.2E-80 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 52 358 1.9E-105 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 20 368 36.668 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 Gene3D G3DSA:1.20.120.420 25 170 4.3E-34 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 28 357 9.7E-108 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 APE_0686 b1ae46036a7f27219cabc2cd1d0244ed 370 SUPERFAMILY SSF100950 27 366 8.37E-111 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_1265.1 48997e5812976ba207ddfb23d495dda6 347 Gene3D G3DSA:3.40.50.720 27 312 5.5E-54 T 23-10-2018 APE_1265.1 48997e5812976ba207ddfb23d495dda6 347 Gene3D G3DSA:3.40.50.720 97 290 5.5E-54 T 23-10-2018 APE_1265.1 48997e5812976ba207ddfb23d495dda6 347 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 289 1.2E-36 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 APE_1265.1 48997e5812976ba207ddfb23d495dda6 347 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 44 321 1.1E-15 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 APE_1265.1 48997e5812976ba207ddfb23d495dda6 347 SUPERFAMILY SSF52283 34 129 4.73E-17 T 23-10-2018 APE_1265.1 48997e5812976ba207ddfb23d495dda6 347 SUPERFAMILY SSF51735 100 290 1.11E-35 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0262 cd05f5f6d81ef53d0501141e5d0d3a54 230 Gene3D G3DSA:3.20.20.190 11 224 5.2E-20 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 APE_0262 cd05f5f6d81ef53d0501141e5d0d3a54 230 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 85 220 6.3E-15 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 APE_0262 cd05f5f6d81ef53d0501141e5d0d3a54 230 SUPERFAMILY SSF51695 12 223 1.05E-22 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 APE_0272.1 359dd98a8021a8cb173127e20ed17879 264 SUPERFAMILY SSF53850 34 216 8.4E-32 T 23-10-2018 APE_0272.1 359dd98a8021a8cb173127e20ed17879 264 Gene3D G3DSA:3.40.190.10 37 247 6.1E-25 T 23-10-2018 APE_0272.1 359dd98a8021a8cb173127e20ed17879 264 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 43 244 1.3E-18 T 23-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 APE_0272.1 359dd98a8021a8cb173127e20ed17879 264 Gene3D G3DSA:3.40.190.10 113 227 6.1E-25 T 23-10-2018 APE_0272.1 359dd98a8021a8cb173127e20ed17879 264 Pfam PF13531 Bacterial extracellular solute-binding protein 37 202 7.6E-22 T 23-10-2018 APE_2057.1 2eab5a5946d6a9bca01132bbaa258a7b 107 SUPERFAMILY SSF46785 4 69 1.96E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 Gene3D G3DSA:3.40.50.300 4 221 8.1E-67 T 23-10-2018 APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 SMART SM00382 28 219 1.7E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 Gene3D G3DSA:2.40.50.140 277 332 7.0E-27 T 23-10-2018 APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 Pfam PF08402 TOBE domain 270 340 1.4E-10 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 Gene3D G3DSA:2.40.50.940 222 341 7.0E-27 T 23-10-2018 APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 Pfam PF00005 ABC transporter 19 161 7.8E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 SUPERFAMILY SSF50331 236 348 1.94E-23 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APE_1635.1 cf35cd4768271592bac864bbfc0652e7 352 SUPERFAMILY SSF52540 4 241 4.03E-91 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0163.1 96d47d390f9c82d3da5cd920cb6eadc0 442 SUPERFAMILY SSF53720 4 373 1.31E-40 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 APE_0163.1 96d47d390f9c82d3da5cd920cb6eadc0 442 Gene3D G3DSA:3.40.605.10 60 199 4.4E-9 T 23-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 APE_0163.1 96d47d390f9c82d3da5cd920cb6eadc0 442 Gene3D G3DSA:3.40.309.10 215 387 1.9E-21 T 23-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 APE_0163.1 96d47d390f9c82d3da5cd920cb6eadc0 442 Pfam PF00171 Aldehyde dehydrogenase family 63 361 1.1E-24 T 23-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 APE_1464 400c4c93b468b85d314a633c20d941fb 388 Pfam PF00202 Aminotransferase class-III 17 382 2.9E-86 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_1464 400c4c93b468b85d314a633c20d941fb 388 Gene3D G3DSA:3.40.640.10 50 290 5.9E-114 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1464 400c4c93b468b85d314a633c20d941fb 388 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 8 383 46.501 T 23-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 APE_1464 400c4c93b468b85d314a633c20d941fb 388 PIRSF PIRSF000521 162 384 8.5E-31 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_1464 400c4c93b468b85d314a633c20d941fb 388 PIRSF PIRSF000521 16 120 2.4E-9 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_1464 400c4c93b468b85d314a633c20d941fb 388 PIRSF PIRSF000521 114 145 0.016 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_1464 400c4c93b468b85d314a633c20d941fb 388 SUPERFAMILY SSF53383 6 382 6.25E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_1464 400c4c93b468b85d314a633c20d941fb 388 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 208 245 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_1464 400c4c93b468b85d314a633c20d941fb 388 Gene3D G3DSA:3.90.1150.10 18 374 5.9E-114 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 225 241 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 Pfam PF00464 Serine hydroxymethyltransferase 22 390 5.0E-65 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 Gene3D G3DSA:3.40.640.10 44 282 1.1E-70 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 SUPERFAMILY SSF53383 8 419 2.16E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 PIRSF PIRSF000412 2 430 1.8E-145 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 Gene3D G3DSA:3.90.1150.10 283 429 1.9E-51 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_1962.1 66199c4b5c8ddef322d7d7505061a9cf 439 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 9 418 37.714 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 APE_2523.1 7d3af56f4815823ffed44866efa2af41 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 19 291 7.6E-34 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_2521.1 46e199d0ad01495aa6f88be269717779 427 Gene3D G3DSA:3.40.50.2300 37 360 2.5E-82 T 23-10-2018 APE_2521.1 46e199d0ad01495aa6f88be269717779 427 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 302 315 1.8E-6 T 23-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 APE_2521.1 46e199d0ad01495aa6f88be269717779 427 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 58 74 1.8E-6 T 23-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 APE_2521.1 46e199d0ad01495aa6f88be269717779 427 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 36 52 1.8E-6 T 23-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 APE_2521.1 46e199d0ad01495aa6f88be269717779 427 Gene3D G3DSA:3.40.50.2300 158 294 2.5E-82 T 23-10-2018 APE_2521.1 46e199d0ad01495aa6f88be269717779 427 Pfam PF13458 Periplasmic binding protein 35 360 4.2E-55 T 23-10-2018 IPR028081 Leucine-binding protein domain APE_2521.1 46e199d0ad01495aa6f88be269717779 427 SUPERFAMILY SSF53822 35 425 1.04E-77 T 23-10-2018 IPR028082 Periplasmic binding protein-like I APE_1717.1 ea0cfbdcd66fbaf41843c58a04740b81 481 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 10 474 71.594 T 23-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_1717.1 ea0cfbdcd66fbaf41843c58a04740b81 481 Gene3D G3DSA:3.90.1300.10 3 476 7.3E-150 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_1717.1 ea0cfbdcd66fbaf41843c58a04740b81 481 ProSitePatterns PS00571 Amidases signature. 151 182 - T 23-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 APE_1717.1 ea0cfbdcd66fbaf41843c58a04740b81 481 SUPERFAMILY SSF75304 5 475 1.83E-130 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_1717.1 ea0cfbdcd66fbaf41843c58a04740b81 481 Pfam PF01425 Amidase 25 462 6.0E-120 T 23-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_2037.1 4cacee0dac55cf8857411a324379ba62 261 Pfam PF02654 Cobalamin-5-phosphate synthase 11 249 2.3E-31 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 APE_2037.1 4cacee0dac55cf8857411a324379ba62 261 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 261 24.903 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 APE_0011.1 7706d707c7c129551ac3c919985611d0 272 PIRSF PIRSF038992 4 272 6.0E-76 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_0011.1 7706d707c7c129551ac3c919985611d0 272 SUPERFAMILY SSF51569 8 260 6.23E-72 T 23-10-2018 APE_0011.1 7706d707c7c129551ac3c919985611d0 272 Gene3D G3DSA:3.20.20.70 5 272 2.1E-81 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0011.1 7706d707c7c129551ac3c919985611d0 272 SMART SM01133 22 244 1.4E-40 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_0011.1 7706d707c7c129551ac3c919985611d0 272 Pfam PF01791 DeoC/LacD family aldolase 23 243 3.0E-36 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 APE_2598 628f0bb186c9efa82ce89b0cd4c0b11e 610 SUPERFAMILY SSF102114 131 383 4.58E-38 T 23-10-2018 APE_2598 628f0bb186c9efa82ce89b0cd4c0b11e 610 Gene3D G3DSA:3.20.20.70 130 406 5.5E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2598 628f0bb186c9efa82ce89b0cd4c0b11e 610 Pfam PF04055 Radical SAM superfamily 146 315 3.9E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_2598 628f0bb186c9efa82ce89b0cd4c0b11e 610 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 148 159 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_2598 628f0bb186c9efa82ce89b0cd4c0b11e 610 Pfam PF13394 4Fe-4S single cluster domain 148 232 5.0E-7 T 23-10-2018 APE_2084.1 48952b3083bf125c07c93f0d0b069296 346 Gene3D G3DSA:1.20.58.220 143 242 1.3E-14 T 23-10-2018 IPR038078 PhoU-like domain superfamily APE_2084.1 48952b3083bf125c07c93f0d0b069296 346 SMART SM00966 13 59 2.8E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_2084.1 48952b3083bf125c07c93f0d0b069296 346 SUPERFAMILY SSF109755 133 333 1.67E-21 T 23-10-2018 APE_2084.1 48952b3083bf125c07c93f0d0b069296 346 Pfam PF01895 PhoU domain 147 235 2.2E-13 T 23-10-2018 IPR026022 PhoU domain APE_2084.1 48952b3083bf125c07c93f0d0b069296 346 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 14 58 1.5E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 SUPERFAMILY SSF52540 4 261 9.57E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 SUPERFAMILY SSF52540 4 906 5.62E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 SUPERFAMILY SSF75712 416 514 2.35E-10 T 23-10-2018 APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Pfam PF04423 Rad50 zinc hook motif 441 492 1.3E-10 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Pfam PF02463 RecF/RecN/SMC N terminal domain 685 912 5.2E-11 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Gene3D G3DSA:3.40.50.300 697 918 3.1E-34 T 23-10-2018 APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Gene3D G3DSA:3.40.50.300 3 297 5.4E-32 T 23-10-2018 APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Gene3D G3DSA:1.10.287.510 414 528 5.4E-9 T 23-10-2018 APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Pfam PF13476 AAA domain 6 260 1.5E-19 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain APE_0110 5d37ba03e7ec40789c14c3578d8eed4c 919 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 2 917 11.693 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type APE_0061.1 60bea4cce316427e9868254eff53a493 429 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 23 5.8E-6 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal APE_0061.1 60bea4cce316427e9868254eff53a493 429 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 50 278 1.7E-18 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 APE_0061.1 60bea4cce316427e9868254eff53a493 429 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 26 5.7E-7 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal APE_0061.1 60bea4cce316427e9868254eff53a493 429 Gene3D G3DSA:3.40.50.2300 51 348 1.7E-68 T 23-10-2018 APE_0061.1 60bea4cce316427e9868254eff53a493 429 Gene3D G3DSA:3.40.50.2300 154 422 1.7E-68 T 23-10-2018 APE_0492.1 498716543e7472d19442e5a2fdab4625 201 Pfam PF00881 Nitroreductase family 18 198 4.1E-23 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APE_0492.1 498716543e7472d19442e5a2fdab4625 201 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 33 198 1.5E-41 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain APE_0492.1 498716543e7472d19442e5a2fdab4625 201 SUPERFAMILY SSF55469 13 198 4.6E-30 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APE_0492.1 498716543e7472d19442e5a2fdab4625 201 Gene3D G3DSA:3.40.109.10 1 199 4.5E-69 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APE_2617a e495102394914f46a0f7abd2309ee05b 86 SMART SM00966 4 50 3.1E-6 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_2617a e495102394914f46a0f7abd2309ee05b 86 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 2 56 0.007 T 23-10-2018 APE_2617a e495102394914f46a0f7abd2309ee05b 86 SUPERFAMILY SSF89447 3 44 1.14E-9 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily APE_2617a e495102394914f46a0f7abd2309ee05b 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 41 4.5E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_2617a e495102394914f46a0f7abd2309ee05b 86 Gene3D G3DSA:2.10.260.10 3 47 2.7E-10 T 23-10-2018 APE_2617a e495102394914f46a0f7abd2309ee05b 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 3.9E-12 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0680a.1 a2320cf4f060c180bef1e347538b1512 98 Pfam PF02680 Uncharacterized ArCR, COG1888 5 92 7.6E-35 T 23-10-2018 IPR003831 Protein of unknown function DUF211 APE_0680a.1 a2320cf4f060c180bef1e347538b1512 98 SUPERFAMILY SSF160363 4 92 9.68E-31 T 23-10-2018 IPR023129 MTH889-like domain superfamily APE_0680a.1 a2320cf4f060c180bef1e347538b1512 98 Gene3D G3DSA:3.30.70.1340 3 88 6.7E-31 T 23-10-2018 IPR023129 MTH889-like domain superfamily APE_0680a.1 a2320cf4f060c180bef1e347538b1512 98 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 90 3.0E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 APE_0919 ff7f4f2f25346b97a0f8df70adc9fd4b 254 Pfam PF00005 ABC transporter 22 181 2.5E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0919 ff7f4f2f25346b97a0f8df70adc9fd4b 254 Gene3D G3DSA:3.40.50.300 3 254 7.4E-67 T 23-10-2018 APE_0919 ff7f4f2f25346b97a0f8df70adc9fd4b 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 231 253 8.9E-9 T 23-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal APE_0919 ff7f4f2f25346b97a0f8df70adc9fd4b 254 SMART SM00382 31 248 7.5E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0919 ff7f4f2f25346b97a0f8df70adc9fd4b 254 SUPERFAMILY SSF52540 3 247 4.51E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0919 ff7f4f2f25346b97a0f8df70adc9fd4b 254 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1098 661da8d549a8cc5141763dc4d1d58576 388 Pfam PF01189 16S rRNA methyltransferase RsmB/F 195 385 1.3E-29 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 APE_1098 661da8d549a8cc5141763dc4d1d58576 388 SUPERFAMILY SSF88697 93 163 7.46E-15 T 23-10-2018 IPR015947 PUA-like superfamily APE_1098 661da8d549a8cc5141763dc4d1d58576 388 SUPERFAMILY SSF53335 165 387 3.95E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1098 661da8d549a8cc5141763dc4d1d58576 388 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 93 162 2.7E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 APE_1098 661da8d549a8cc5141763dc4d1d58576 388 Pfam PF01472 PUA domain 93 163 3.2E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 APE_1098 661da8d549a8cc5141763dc4d1d58576 388 Gene3D G3DSA:3.40.50.150 191 388 8.5E-45 T 23-10-2018 APE_1098 661da8d549a8cc5141763dc4d1d58576 388 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 274 286 1.7E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_1098 661da8d549a8cc5141763dc4d1d58576 388 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 205 215 1.7E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_1098 661da8d549a8cc5141763dc4d1d58576 388 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 370 387 1.7E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_1098 661da8d549a8cc5141763dc4d1d58576 388 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 321 337 1.7E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_1098 661da8d549a8cc5141763dc4d1d58576 388 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 176 190 1.7E-20 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_1098 661da8d549a8cc5141763dc4d1d58576 388 SMART SM00359 93 166 1.3E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 APE_1098 661da8d549a8cc5141763dc4d1d58576 388 Gene3D G3DSA:2.30.130.70 80 170 4.4E-17 T 23-10-2018 APE_2601.1 270d9dfb93df0dcb9baf68fe58ec793d 270 Gene3D G3DSA:3.75.10.10 7 268 4.7E-57 T 23-10-2018 APE_2601.1 270d9dfb93df0dcb9baf68fe58ec793d 270 SUPERFAMILY SSF55909 12 267 5.0E-52 T 23-10-2018 APE_2601.1 270d9dfb93df0dcb9baf68fe58ec793d 270 Pfam PF02274 Amidinotransferase 196 267 1.4E-7 T 23-10-2018 APE_2601.1 270d9dfb93df0dcb9baf68fe58ec793d 270 Pfam PF02274 Amidinotransferase 65 157 2.1E-10 T 23-10-2018 APE_2578 8bcc85a437a0bbd8716645e63ad3311c 283 PIRSF PIRSF006648 1 281 1.2E-81 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2578 8bcc85a437a0bbd8716645e63ad3311c 283 PRINTS PR00164 ABC-2 type transport system membrane protein signature 224 243 3.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2578 8bcc85a437a0bbd8716645e63ad3311c 283 PRINTS PR00164 ABC-2 type transport system membrane protein signature 82 104 3.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2578 8bcc85a437a0bbd8716645e63ad3311c 283 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 3.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2578 8bcc85a437a0bbd8716645e63ad3311c 283 Pfam PF01061 ABC-2 type transporter 9 245 2.6E-31 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 18 366 8.2E-110 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 803 0.0 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Gene3D G3DSA:3.50.30.10 373 483 6.6E-44 T 23-10-2018 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Gene3D G3DSA:3.20.20.60 508 802 4.0E-95 T 23-10-2018 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 SUPERFAMILY SSF51621 492 808 9.68E-96 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 PIRSF PIRSF000854 1 807 2.1E-242 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Gene3D G3DSA:3.30.470.20 193 368 5.0E-42 T 23-10-2018 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 705 723 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Pfam PF00391 PEP-utilising enzyme, mobile domain 403 474 4.6E-29 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 SUPERFAMILY SSF52009 372 483 1.96E-38 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 SUPERFAMILY SSF56059 4 396 7.65E-95 T 23-10-2018 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 433 444 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 498 802 2.4E-84 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 APE_0650.1 03979eb90f5fa69fd41ab21ef35b4b48 820 Gene3D G3DSA:3.30.1490.20 1 192 1.3E-66 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 SUPERFAMILY SSF48256 10 391 2.36E-113 T 23-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PIRSF PIRSF001369 11 392 5.4E-106 T 23-10-2018 IPR024176 Citrate synthase, bacterial-type APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PRINTS PR00143 Citrate synthase signature 186 201 4.6E-37 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PRINTS PR00143 Citrate synthase signature 344 358 4.6E-37 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PRINTS PR00143 Citrate synthase signature 137 150 4.6E-37 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PRINTS PR00143 Citrate synthase signature 324 340 4.6E-37 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PRINTS PR00143 Citrate synthase signature 270 290 4.6E-37 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 PRINTS PR00143 Citrate synthase signature 208 236 4.6E-37 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 Gene3D G3DSA:1.10.230.10 235 341 1.8E-101 T 23-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain APE_1713 21f9b740105c0987cac89a04654ea7ef 394 Gene3D G3DSA:1.10.580.10 30 365 1.8E-101 T 23-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 ProSitePatterns PS00480 Citrate synthase signature. 277 289 - T 23-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 APE_1713 21f9b740105c0987cac89a04654ea7ef 394 Pfam PF00285 Citrate synthase, C-terminal domain 19 374 2.8E-107 T 23-10-2018 IPR002020 Citrate synthase GO:0046912 APE_1666 7e48eb4ae1c5f93025196a9465ec8f44 268 Pfam PF01966 HD domain 74 179 1.1E-8 T 23-10-2018 IPR006674 HD domain APE_1666 7e48eb4ae1c5f93025196a9465ec8f44 268 SMART SM00471 50 189 5.1E-4 T 23-10-2018 IPR003607 HD/PDEase domain APE_1666 7e48eb4ae1c5f93025196a9465ec8f44 268 Gene3D G3DSA:1.10.3210.10 24 208 2.0E-9 T 23-10-2018 APE_1666 7e48eb4ae1c5f93025196a9465ec8f44 268 SUPERFAMILY SSF109604 89 188 7.54E-9 T 23-10-2018 APE_0519.1 b18cce7be735ff154e47bf41330152ee 352 Gene3D G3DSA:3.40.50.1970 2 160 9.8E-32 T 23-10-2018 APE_0519.1 b18cce7be735ff154e47bf41330152ee 352 PIRSF PIRSF000112 2 349 6.5E-63 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 APE_0519.1 b18cce7be735ff154e47bf41330152ee 352 Gene3D G3DSA:1.20.1090.10 162 351 5.5E-62 T 23-10-2018 APE_0519.1 b18cce7be735ff154e47bf41330152ee 352 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 7 352 44.339 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 APE_0519.1 b18cce7be735ff154e47bf41330152ee 352 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 274 1.8E-63 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 APE_0519.1 b18cce7be735ff154e47bf41330152ee 352 SUPERFAMILY SSF56796 4 337 5.76E-69 T 23-10-2018 APE_0972.1 494a7fc7f1fb8244d3ec21a76ebd7be7 490 Pfam PF00474 Sodium:solute symporter family 38 392 2.2E-22 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 APE_0972.1 494a7fc7f1fb8244d3ec21a76ebd7be7 490 Gene3D G3DSA:1.20.1730.10 5 485 2.6E-40 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily APE_1331 80872d48e164ff51e9d429f352921b3a 562 Pfam PF02538 Hydantoinase B/oxoprolinase 4 520 1.9E-185 T 23-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 APE_1041 251d976874ba58b1c1a0ec8c9654b444 143 Pfam PF06695 Putative small multi-drug export protein 2 130 5.2E-22 T 23-10-2018 IPR009577 Putative small multi-drug export APE_0669.1 67ea1db02310346711f8b9d5961f0884 224 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 18 218 8.1E-40 T 23-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 APE_0669.1 67ea1db02310346711f8b9d5961f0884 224 Gene3D G3DSA:1.20.910.10 2 224 1.3E-56 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 APE_0669.1 67ea1db02310346711f8b9d5961f0884 224 Pfam PF03070 TENA/THI-4/PQQC family 16 218 4.9E-62 T 23-10-2018 IPR004305 Thiaminase-2/PQQC APE_0669.1 67ea1db02310346711f8b9d5961f0884 224 SUPERFAMILY SSF48613 6 220 1.08E-58 T 23-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 Pfam PF01336 OB-fold nucleic acid binding domain 22 100 2.3E-13 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 442 39.891 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 Gene3D G3DSA:2.40.50.140 8 109 2.5E-23 T 23-10-2018 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 436 2.8E-84 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 16 442 5.6E-135 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 PRINTS PR01042 Aspartyl-tRNA synthetase signature 189 201 3.3E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 PRINTS PR01042 Aspartyl-tRNA synthetase signature 357 373 3.3E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 PRINTS PR01042 Aspartyl-tRNA synthetase signature 397 411 3.3E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 PRINTS PR01042 Aspartyl-tRNA synthetase signature 206 219 3.3E-19 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 Gene3D G3DSA:3.30.930.10 110 442 7.0E-101 T 23-10-2018 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 SUPERFAMILY SSF55681 98 441 8.89E-85 T 23-10-2018 APE_2192.1 0b0953fd718885f2f69176837bf9230b 442 SUPERFAMILY SSF50249 13 108 6.0E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 SUPERFAMILY SSF46924 1 63 5.75E-23 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 18.857 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 Gene3D G3DSA:1.10.10.60 1 66 1.3E-24 T 23-10-2018 APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 4.0E-17 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 57 1.0E-24 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1749a 4156b9ab9d1da9761c1e3d1efa9337f4 77 PIRSF PIRSF005653 1 73 2.0E-27 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_2526 cb73cfbdea1f196e8558716966b4345a 240 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_2526 cb73cfbdea1f196e8558716966b4345a 240 SUPERFAMILY SSF52540 4 238 4.35E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2526 cb73cfbdea1f196e8558716966b4345a 240 Pfam PF00005 ABC transporter 24 167 1.3E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2526 cb73cfbdea1f196e8558716966b4345a 240 SMART SM00382 31 224 2.2E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2526 cb73cfbdea1f196e8558716966b4345a 240 Gene3D G3DSA:3.40.50.300 2 240 2.9E-60 T 23-10-2018 APE_2295.1 5a07a73cef7524f5d1665ded4cb92d7b 326 Pfam PF12706 Beta-lactamase superfamily domain 32 148 1.1E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2295.1 5a07a73cef7524f5d1665ded4cb92d7b 326 Gene3D G3DSA:3.60.15.10 8 167 3.1E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_2295.1 5a07a73cef7524f5d1665ded4cb92d7b 326 SUPERFAMILY SSF56281 32 316 2.1E-33 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_2537.1 6a59a1c1be0b59265dcf729128ce4164 322 Pfam PF00892 EamA-like transporter family 168 303 2.4E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_2537.1 6a59a1c1be0b59265dcf729128ce4164 322 Pfam PF00892 EamA-like transporter family 17 151 4.7E-8 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_2537.1 6a59a1c1be0b59265dcf729128ce4164 322 SUPERFAMILY SSF103481 207 306 1.18E-9 T 23-10-2018 APE_2537.1 6a59a1c1be0b59265dcf729128ce4164 322 SUPERFAMILY SSF103481 57 155 1.44E-11 T 23-10-2018 APE_1829 094e1696ffe8b23b14f0f0b84b189c56 345 Pfam PF00005 ABC transporter 28 174 4.7E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1829 094e1696ffe8b23b14f0f0b84b189c56 345 Gene3D G3DSA:3.40.50.300 2 246 3.4E-60 T 23-10-2018 APE_1829 094e1696ffe8b23b14f0f0b84b189c56 345 SMART SM00382 37 231 4.2E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1829 094e1696ffe8b23b14f0f0b84b189c56 345 SUPERFAMILY SSF52540 5 235 3.48E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1829 094e1696ffe8b23b14f0f0b84b189c56 345 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 SUPERFAMILY SSF51905 114 241 2.79E-25 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.6E-5 T 23-10-2018 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 1.6E-5 T 23-10-2018 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 Gene3D G3DSA:3.50.50.100 1 380 6.3E-88 T 23-10-2018 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 284 1.4E-22 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 5.0E-7 T 23-10-2018 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.0E-7 T 23-10-2018 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 96 114 5.0E-7 T 23-10-2018 APE_1043.1 f64f5e22299d3c0e983a488a0ab2a487 381 SUPERFAMILY SSF51905 2 312 3.28E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1498.1 0af53f7c70b52071c823c9f6fc5da7a0 411 Gene3D G3DSA:3.40.50.1100 61 157 2.7E-112 T 23-10-2018 APE_1498.1 0af53f7c70b52071c823c9f6fc5da7a0 411 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 32 410 5.3E-184 T 23-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 APE_1498.1 0af53f7c70b52071c823c9f6fc5da7a0 411 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 313 1.5E-84 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_1498.1 0af53f7c70b52071c823c9f6fc5da7a0 411 SUPERFAMILY SSF53686 11 361 3.27E-97 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_1498.1 0af53f7c70b52071c823c9f6fc5da7a0 411 SUPERFAMILY SSF55021 340 404 3.93E-5 T 23-10-2018 APE_1498.1 0af53f7c70b52071c823c9f6fc5da7a0 411 Gene3D G3DSA:3.40.50.1100 20 318 2.7E-112 T 23-10-2018 APE_1647 c8ecea6e579c5ffb5d6bfd826d163456 197 SUPERFAMILY SSF52507 8 192 3.4E-39 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 APE_1647 c8ecea6e579c5ffb5d6bfd826d163456 197 Gene3D G3DSA:3.40.50.1950 8 196 7.9E-54 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 APE_1647 c8ecea6e579c5ffb5d6bfd826d163456 197 Pfam PF02441 Flavoprotein 8 171 3.8E-18 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 APE_1647 c8ecea6e579c5ffb5d6bfd826d163456 197 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 10 190 6.1E-51 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like APE_1647 c8ecea6e579c5ffb5d6bfd826d163456 197 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 6 192 30.663 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like APE_1164 0658a88e4fb44df2091bb73ab8412104 410 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 81 96 9.4E-26 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 8 28 9.4E-26 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 29 47 9.4E-26 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 98 116 9.4E-26 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 Gene3D G3DSA:1.10.8.470 134 225 5.6E-64 T 23-10-2018 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 Pfam PF02824 TGS domain 347 404 6.0E-17 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 Pfam PF08438 GTPase of unknown function C-terminal 231 338 2.1E-32 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal APE_1164 0658a88e4fb44df2091bb73ab8412104 410 SUPERFAMILY SSF52540 7 287 9.01E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1164 0658a88e4fb44df2091bb73ab8412104 410 Gene3D G3DSA:3.40.50.300 8 279 5.6E-64 T 23-10-2018 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 Pfam PF01926 50S ribosome-binding GTPase 9 124 1.3E-17 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_1164 0658a88e4fb44df2091bb73ab8412104 410 Gene3D G3DSA:3.10.20.30 330 407 5.3E-32 T 23-10-2018 IPR012675 Beta-grasp domain superfamily APE_1164 0658a88e4fb44df2091bb73ab8412104 410 SUPERFAMILY SSF81271 333 404 3.27E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 APE_1687 6743d7fa649c8cee698cbf92cbb278ce 565 Pfam PF01642 Methylmalonyl-CoA mutase 39 557 2.0E-220 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 APE_1687 6743d7fa649c8cee698cbf92cbb278ce 565 Gene3D G3DSA:3.20.20.240 1 565 6.2E-248 T 23-10-2018 APE_1687 6743d7fa649c8cee698cbf92cbb278ce 565 SUPERFAMILY SSF51703 17 559 2.54E-213 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 APE_1687 6743d7fa649c8cee698cbf92cbb278ce 565 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 38 564 1.1E-273 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 4.3E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 SMART SM00382 34 240 3.4E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 SUPERFAMILY SSF52540 34 316 2.15E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 2.7E-29 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 Pfam PF00005 ABC transporter 26 182 1.4E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1578 a97e9b2710eaefef1b7a6165d0f3d040 324 Gene3D G3DSA:3.40.50.300 3 322 2.4E-104 T 23-10-2018 APE_1361.1 32c3d14cd89068f1bb0d39ddce28ada7 260 SUPERFAMILY SSF51735 8 252 2.25E-33 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1361.1 32c3d14cd89068f1bb0d39ddce28ada7 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 252 1.3E-23 T 23-10-2018 APE_1361.1 32c3d14cd89068f1bb0d39ddce28ada7 260 Gene3D G3DSA:3.40.50.720 7 255 2.3E-34 T 23-10-2018 APE_2048 23da0e2346441cb45545ca9c5ed2aec5 332 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 326 6.0E-69 T 23-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 APE_2048 23da0e2346441cb45545ca9c5ed2aec5 332 SUPERFAMILY SSF51726 13 331 5.23E-84 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APE_2048 23da0e2346441cb45545ca9c5ed2aec5 332 Gene3D G3DSA:3.20.20.210 2 332 2.1E-109 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APE_2048 23da0e2346441cb45545ca9c5ed2aec5 332 Hamap MF_00288 Methionine synthase [metE]. 11 328 46.958 T 23-10-2018 IPR022921 Methionine synthase MetE, archaeal GO:0008168|GO:0009086 APE_2200 deec55165ed832339a27af326cd41046 427 SUPERFAMILY SSF141300 4 53 2.62E-12 T 23-10-2018 IPR037222 GatD, N-terminal APE_2200 deec55165ed832339a27af326cd41046 427 Gene3D G3DSA:3.40.50.40 286 423 1.9E-48 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 153 163 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 75 413 1.1E-120 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 Pfam PF00710 Asparaginase, N-terminal 75 269 2.4E-61 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 SUPERFAMILY SSF53774 71 419 5.1E-105 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 PIRSF PIRSF500175 1 421 2.0E-169 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 APE_2200 deec55165ed832339a27af326cd41046 427 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 10 417 1.9E-183 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 APE_2200 deec55165ed832339a27af326cd41046 427 PRINTS PR00139 Asparaginase/glutaminase family signature 338 356 3.4E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 PRINTS PR00139 Asparaginase/glutaminase family signature 152 170 3.4E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 PRINTS PR00139 Asparaginase/glutaminase family signature 76 87 3.4E-17 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 Gene3D G3DSA:3.40.50.1170 66 285 1.5E-72 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 SMART SM00870 75 401 5.5E-138 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 PIRSF PIRSF001220 70 412 5.0E-103 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 APE_2200 deec55165ed832339a27af326cd41046 427 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 1 417 46.224 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 APE_2200 deec55165ed832339a27af326cd41046 427 Gene3D G3DSA:2.30.30.520 1 55 2.8E-11 T 23-10-2018 IPR037222 GatD, N-terminal APE_1267.1 62a6b510a67c7743eee1cb4c5b7e7714 428 Gene3D G3DSA:3.30.9.10 85 355 4.8E-147 T 23-10-2018 APE_1267.1 62a6b510a67c7743eee1cb4c5b7e7714 428 SUPERFAMILY SSF51905 4 412 1.23E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1267.1 62a6b510a67c7743eee1cb4c5b7e7714 428 Gene3D G3DSA:3.50.50.60 4 397 4.8E-147 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1267.1 62a6b510a67c7743eee1cb4c5b7e7714 428 Pfam PF01266 FAD dependent oxidoreductase 5 393 2.1E-41 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APE_1901 d8c324a4cc5077f999d089e03b93f8fc 161 Pfam PF01917 Archaebacterial flagellin 5 156 1.4E-20 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 APE_1104.1 6b02068b4c47b2f819eeb00946c5be47 280 Pfam PF01513 ATP-NAD kinase 61 259 8.5E-35 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 APE_1104.1 6b02068b4c47b2f819eeb00946c5be47 280 Gene3D G3DSA:3.40.50.10330 24 276 2.2E-51 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 APE_1104.1 6b02068b4c47b2f819eeb00946c5be47 280 Gene3D G3DSA:2.60.200.30 123 254 2.2E-51 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 APE_1104.1 6b02068b4c47b2f819eeb00946c5be47 280 Hamap MF_00361 NAD kinase [nadK]. 3 278 24.355 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 APE_1104.1 6b02068b4c47b2f819eeb00946c5be47 280 SUPERFAMILY SSF111331 5 276 2.22E-59 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily APE_0358 4f780d591dfdb36a1408eaa490079a12 132 SUPERFAMILY SSF50104 7 117 2.88E-36 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily APE_0358 4f780d591dfdb36a1408eaa490079a12 132 ProSitePatterns PS01108 Ribosomal protein L24 signature. 51 68 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0358 4f780d591dfdb36a1408eaa490079a12 132 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 7 120 32.648 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0358 4f780d591dfdb36a1408eaa490079a12 132 Gene3D G3DSA:2.30.30.30 4 131 5.5E-52 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 APE_0358 4f780d591dfdb36a1408eaa490079a12 132 SMART SM00739 47 74 9.0E-7 T 23-10-2018 IPR005824 KOW APE_0358 4f780d591dfdb36a1408eaa490079a12 132 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 7 121 2.3E-34 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0358 4f780d591dfdb36a1408eaa490079a12 132 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 7 122 2.3E-55 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0358 4f780d591dfdb36a1408eaa490079a12 132 Pfam PF00467 KOW motif 50 81 2.5E-9 T 23-10-2018 IPR005824 KOW APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 264 276 - T 23-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 Pfam PF00490 Delta-aminolevulinic acid dehydratase 22 344 9.9E-130 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PIRSF PIRSF001415 12 349 1.1E-142 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 Gene3D G3DSA:3.20.20.70 16 351 5.3E-132 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 SMART SM01004 19 346 2.4E-193 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 174 193 7.8E-55 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 320 339 7.8E-55 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 264 280 7.8E-55 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 212 231 7.8E-55 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 290 305 7.8E-55 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 140 154 7.8E-55 T 23-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 APE_2300.1 b6113fd7c4c7b80082d869db5d22d49b 353 SUPERFAMILY SSF51569 16 347 3.81E-123 T 23-10-2018 APE_0291 d09a191bf8d4e48cb859b6862cb238a6 110 SUPERFAMILY SSF52833 1 101 4.42E-36 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_0291 d09a191bf8d4e48cb859b6862cb238a6 110 Pfam PF00578 AhpC/TSA family 4 101 1.2E-29 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_0291 d09a191bf8d4e48cb859b6862cb238a6 110 Gene3D G3DSA:3.40.30.10 1 109 5.7E-32 T 23-10-2018 APE_1949.1 58c3714f99ee8273363f8ea3944cf669 211 Gene3D G3DSA:2.20.25.420 25 76 5.8E-8 T 23-10-2018 APE_1949.1 58c3714f99ee8273363f8ea3944cf669 211 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 33 190 1.5E-40 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 APE_1949.1 58c3714f99ee8273363f8ea3944cf669 211 SMART SM00709 31 188 5.0E-72 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 APE_1949.1 58c3714f99ee8273363f8ea3944cf669 211 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 33 209 1.5E-34 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 APE_1949.1 58c3714f99ee8273363f8ea3944cf669 211 Pfam PF03367 ZPR1 zinc-finger domain 32 186 2.0E-33 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 APE_1949.1 58c3714f99ee8273363f8ea3944cf669 211 Gene3D G3DSA:2.60.120.1040 78 204 1.9E-14 T 23-10-2018 APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 Gene3D G3DSA:2.40.50.140 3 108 3.0E-29 T 23-10-2018 APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 31 53 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 43 93 4.0E-23 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 SUPERFAMILY SSF50249 13 103 9.71E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 5 100 26.272 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 SMART SM00652 18 100 1.6E-41 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 APE_0748a 33de7457b6e05dbbb9c14792ee24f888 111 Pfam PF01176 Translation initiation factor 1A / IF-1 23 84 1.9E-18 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 APE_2489.1 ac093bd78997ac39024d780b8dcb8c7d 148 SUPERFAMILY SSF54631 13 134 2.02E-39 T 23-10-2018 APE_2489.1 ac093bd78997ac39024d780b8dcb8c7d 148 Gene3D G3DSA:3.10.580.10 6 141 1.2E-40 T 23-10-2018 APE_2489.1 ac093bd78997ac39024d780b8dcb8c7d 148 SMART SM00116 87 135 1.2E-12 T 23-10-2018 IPR000644 CBS domain APE_2489.1 ac093bd78997ac39024d780b8dcb8c7d 148 SMART SM00116 22 70 1.8E-13 T 23-10-2018 IPR000644 CBS domain APE_2489.1 ac093bd78997ac39024d780b8dcb8c7d 148 Pfam PF00571 CBS domain 82 135 3.5E-17 T 23-10-2018 IPR000644 CBS domain APE_2489.1 ac093bd78997ac39024d780b8dcb8c7d 148 Pfam PF00571 CBS domain 15 69 2.0E-14 T 23-10-2018 IPR000644 CBS domain APE_2296 181dc09222eb0908c421718a49191053 416 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 401 20.021 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 Gene3D G3DSA:3.30.460.30 2 148 4.4E-34 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 143 1.8E-31 T 23-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 SUPERFAMILY SSF69075 301 393 1.7E-13 T 23-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 Gene3D G3DSA:3.40.50.720 149 293 1.4E-16 T 23-10-2018 APE_2296 181dc09222eb0908c421718a49191053 416 SUPERFAMILY SSF51735 149 276 5.04E-16 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_2296 181dc09222eb0908c421718a49191053 416 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 160 283 4.3E-25 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase APE_2296 181dc09222eb0908c421718a49191053 416 SUPERFAMILY SSF69742 5 146 5.23E-32 T 23-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 87 110 - T 23-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 PIRSF PIRSF000445 3 413 1.7E-82 T 23-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_2296 181dc09222eb0908c421718a49191053 416 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 304 387 6.6E-7 T 23-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.7E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 2.7E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 75 90 2.7E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 SMART SM00418 21 112 1.7E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 SUPERFAMILY SSF46785 23 137 9.4E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 Gene3D G3DSA:1.10.10.10 18 100 3.5E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0290.1 aed0b906cc4af6006d613ac013dee05b 181 Pfam PF12840 Helix-turn-helix domain 23 84 5.5E-12 T 23-10-2018 APE_0921 96ebe44a09975037547296d97a879733 237 SUPERFAMILY SSF52540 4 234 2.15E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0921 96ebe44a09975037547296d97a879733 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0921 96ebe44a09975037547296d97a879733 237 Gene3D G3DSA:3.40.50.300 1 237 9.9E-62 T 23-10-2018 APE_0921 96ebe44a09975037547296d97a879733 237 SMART SM00382 30 214 8.7E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0921 96ebe44a09975037547296d97a879733 237 Pfam PF00005 ABC transporter 23 166 1.6E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 PIRSF PIRSF001456 4 370 1.3E-139 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 Hamap MF_00300 Chorismate synthase [aroC]. 11 363 36.517 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 SUPERFAMILY SSF103263 5 358 1.57E-122 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 ProSitePatterns PS00788 Chorismate synthase signature 2. 125 141 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 TIGRFAM TIGR00033 aroC: chorismate synthase 11 357 7.5E-122 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 Pfam PF01264 Chorismate synthase 11 356 1.2E-122 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 ProSitePatterns PS00787 Chorismate synthase signature 1. 17 32 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 ProSitePatterns PS00789 Chorismate synthase signature 3. 330 346 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_0564 dd1ce1da65ba51c72f4e230cb6409ea9 380 Gene3D G3DSA:3.60.150.10 3 370 6.4E-134 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 APE_1307 26d754afedc79644b8daf87433f27543 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 23-10-2018 IPR020845 AMP-binding, conserved site APE_1307 26d754afedc79644b8daf87433f27543 651 Gene3D G3DSA:3.40.50.12780 337 482 2.5E-35 T 23-10-2018 APE_1307 26d754afedc79644b8daf87433f27543 651 Pfam PF00501 AMP-binding enzyme 27 489 6.4E-91 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_1307 26d754afedc79644b8daf87433f27543 651 SUPERFAMILY SSF56801 19 621 1.19E-98 T 23-10-2018 APE_1307 26d754afedc79644b8daf87433f27543 651 Gene3D G3DSA:3.40.50.12780 18 336 1.7E-31 T 23-10-2018 APE_0104a.1 81dd4f1c7944e9a34f7c213c26434ebe 74 SUPERFAMILY SSF54862 9 69 3.52E-6 T 23-10-2018 APE_0104a.1 81dd4f1c7944e9a34f7c213c26434ebe 74 Gene3D G3DSA:3.30.70.20 1 68 1.1E-12 T 23-10-2018 APE_0104a.1 81dd4f1c7944e9a34f7c213c26434ebe 74 Pfam PF13459 4Fe-4S single cluster domain 4 67 6.8E-17 T 23-10-2018 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 Gene3D G3DSA:3.30.70.141 1 141 6.2E-60 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 SUPERFAMILY SSF54919 2 141 4.84E-58 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 SMART SM00562 3 140 1.5E-86 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 Pfam PF00334 Nucleoside diphosphate kinase 4 138 3.3E-57 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 36.689 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.0E-41 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 3.0E-41 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 3.0E-41 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 3.0E-41 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2377 456e9f52dabaaf3715df10cd2bca3533 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.0E-41 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2112.1 1fa8286c7081451fcaade9c4c877ff5d 132 Hamap MF_01285 Riboflavin kinase [ribK]. 4 129 23.514 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 APE_2112.1 1fa8286c7081451fcaade9c4c877ff5d 132 SUPERFAMILY SSF82114 4 129 2.58E-34 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 APE_2112.1 1fa8286c7081451fcaade9c4c877ff5d 132 Pfam PF01982 Domain of unknown function DUF120 10 127 7.8E-32 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 APE_2112.1 1fa8286c7081451fcaade9c4c877ff5d 132 Gene3D G3DSA:2.40.30.30 3 131 2.3E-33 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 SUPERFAMILY SSF54999 4 100 2.49E-30 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 23.702 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 4 100 2.2E-51 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 Gene3D G3DSA:3.30.70.600 2 101 9.3E-33 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 Pfam PF00338 Ribosomal protein S10p/S20e 6 100 1.1E-26 T 23-10-2018 IPR027486 Ribosomal protein S10 domain APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 3.9E-12 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 3.9E-12 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.9E-12 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1842 5bcd0959bbcdcf80344561db3715e8a9 104 SMART SM01403 6 100 7.7E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain APE_0179 d18631a57bb33e9b0f6bfc1e01a8ec25 281 Gene3D G3DSA:3.90.550.10 5 205 5.4E-25 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0179 d18631a57bb33e9b0f6bfc1e01a8ec25 281 SUPERFAMILY SSF53448 7 200 3.03E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0179 d18631a57bb33e9b0f6bfc1e01a8ec25 281 Pfam PF12804 MobA-like NTP transferase domain 10 174 1.2E-20 T 23-10-2018 IPR025877 MobA-like NTP transferase APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 Gene3D G3DSA:3.65.10.20 9 333 2.2E-108 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 6 350 37.392 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 Gene3D G3DSA:3.30.360.20 188 287 2.2E-108 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 186 286 6.2E-19 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 PIRSF PIRSF005378 3 361 4.7E-119 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 159 169 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 SUPERFAMILY SSF55205 7 220 1.77E-64 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 SUPERFAMILY SSF52913 187 290 7.19E-20 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 Pfam PF01137 RNA 3'-terminal phosphate cyclase 13 333 3.4E-76 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain APE_0511.1 f7ff9c1d7e25af73dd7bdab3d303a001 361 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 7 330 1.5E-115 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 Pfam PF13242 HAD-hyrolase-like 189 259 8.3E-11 T 23-10-2018 APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 PIRSF PIRSF000915 5 255 2.3E-60 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 SUPERFAMILY SSF56784 7 247 1.14E-48 T 23-10-2018 IPR036412 HAD-like superfamily APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 Pfam PF13344 Haloacid dehalogenase-like hydrolase 14 108 2.4E-21 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 13 236 1.5E-36 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 Gene3D G3DSA:3.40.50.1000 77 189 1.8E-71 T 23-10-2018 IPR023214 HAD superfamily APE_1605.1 bb1bbded88a97c9cc74b40c1ef781f66 267 Gene3D G3DSA:3.40.50.1000 15 247 1.8E-71 T 23-10-2018 IPR023214 HAD superfamily APE_2105.1 eb95ea20b179d965b034f5e1c0ae8819 282 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 77 92 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 APE_2105.1 eb95ea20b179d965b034f5e1c0ae8819 282 SUPERFAMILY SSF53167 19 248 8.25E-71 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APE_2105.1 eb95ea20b179d965b034f5e1c0ae8819 282 Pfam PF01048 Phosphorylase superfamily 32 256 9.1E-45 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 APE_2105.1 eb95ea20b179d965b034f5e1c0ae8819 282 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 19 258 3.8E-93 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 APE_2105.1 eb95ea20b179d965b034f5e1c0ae8819 282 Gene3D G3DSA:3.40.50.1580 16 269 4.6E-81 T 23-10-2018 APE_0424a d16bf1d8e5e90a22c7363c25768e973b 68 Gene3D G3DSA:2.30.30.860 3 68 7.7E-23 T 23-10-2018 APE_0436b.1 b48420b5f4f02ecc69b3a0a11e88adc2 95 Gene3D G3DSA:3.10.450.80 1 95 3.5E-31 T 23-10-2018 APE_0436b.1 b48420b5f4f02ecc69b3a0a11e88adc2 95 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 3.0E-25 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0436b.1 b48420b5f4f02ecc69b3a0a11e88adc2 95 Pfam PF00935 Ribosomal protein L44 16 91 1.8E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0436b.1 b48420b5f4f02ecc69b3a0a11e88adc2 95 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 23.273 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0436b.1 b48420b5f4f02ecc69b3a0a11e88adc2 95 SUPERFAMILY SSF57829 2 91 1.83E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APE_0688 7928ea04bb31cdf7a48d57b692488f11 324 Gene3D G3DSA:3.10.180.10 66 215 1.2E-103 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_0688 7928ea04bb31cdf7a48d57b692488f11 324 SUPERFAMILY SSF54593 2 298 3.86E-45 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_0688 7928ea04bb31cdf7a48d57b692488f11 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 159 271 4.9E-14 T 23-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APE_0688 7928ea04bb31cdf7a48d57b692488f11 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 48 3.0E-9 T 23-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain APE_0688 7928ea04bb31cdf7a48d57b692488f11 324 Gene3D G3DSA:3.10.180.10 6 309 1.2E-103 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 SUPERFAMILY SSF55031 201 330 2.99E-18 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 SUPERFAMILY SSF53187 12 411 7.43E-56 T 23-10-2018 APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 Gene3D G3DSA:3.30.70.360 201 330 1.2E-87 T 23-10-2018 APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 Pfam PF01546 Peptidase family M20/M25/M40 92 407 5.7E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 Gene3D G3DSA:3.40.630.10 21 398 1.2E-87 T 23-10-2018 APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 Pfam PF07687 Peptidase dimerisation domain 198 309 4.8E-19 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain APE_0632.1 08519de4d2adb40f1c72af8b11d3a1ab 419 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 18 398 2.3E-76 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase APE_1588 dc9baed6e0d4de27247dc72a45dbdf45 132 Gene3D G3DSA:3.40.50.1010 4 128 6.9E-11 T 23-10-2018 APE_1588 dc9baed6e0d4de27247dc72a45dbdf45 132 SUPERFAMILY SSF88723 1 120 1.82E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_1588 dc9baed6e0d4de27247dc72a45dbdf45 132 Pfam PF01850 PIN domain 5 120 3.0E-10 T 23-10-2018 IPR002716 PIN domain APE_0929.1 d04711b4d6487210644679b96ce86f56 397 Pfam PF02803 Thiolase, C-terminal domain 258 359 1.4E-7 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 APE_0929.1 d04711b4d6487210644679b96ce86f56 397 Gene3D G3DSA:3.40.47.10 4 392 6.5E-121 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_0929.1 d04711b4d6487210644679b96ce86f56 397 SUPERFAMILY SSF53901 232 388 6.86E-25 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_0929.1 d04711b4d6487210644679b96ce86f56 397 PIRSF PIRSF000429 2 390 1.6E-60 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_0929.1 d04711b4d6487210644679b96ce86f56 397 SUPERFAMILY SSF53901 5 229 8.2E-47 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_0929.1 d04711b4d6487210644679b96ce86f56 397 Pfam PF00108 Thiolase, N-terminal domain 5 224 1.2E-24 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 APE_0105 38476aee90836873984952109eb2cf7b 263 SUPERFAMILY SSF52540 6 169 9.82E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0105 38476aee90836873984952109eb2cf7b 263 PIRSF PIRSF006230 1 263 1.1E-57 T 23-10-2018 IPR016478 GTPase, MTG1 APE_0105 38476aee90836873984952109eb2cf7b 263 Pfam PF03193 RsgA GTPase 8 160 4.0E-12 T 23-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 APE_0105 38476aee90836873984952109eb2cf7b 263 Gene3D G3DSA:3.40.50.300 5 162 9.6E-36 T 23-10-2018 APE_0105 38476aee90836873984952109eb2cf7b 263 Gene3D G3DSA:1.10.1580.10 172 252 9.3E-7 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily APE_2612.1 f689ef09e2bb9a42fbb963a8abae7e9d 194 Gene3D G3DSA:1.10.3480.10 38 191 4.3E-31 T 23-10-2018 APE_2612.1 f689ef09e2bb9a42fbb963a8abae7e9d 194 Pfam PF02613 Nitrate reductase delta subunit 89 151 5.7E-6 T 23-10-2018 IPR020945 DMSO/Nitrate reductase chaperone APE_2612.1 f689ef09e2bb9a42fbb963a8abae7e9d 194 SUPERFAMILY SSF89155 87 171 1.31E-15 T 23-10-2018 IPR036411 TorD-like superfamily APE_1497.1 b55b6ee3815dfb91bcd90eceffff95d7 324 Gene3D G3DSA:3.30.70.3460 201 324 9.7E-10 T 23-10-2018 APE_1497.1 b55b6ee3815dfb91bcd90eceffff95d7 324 Gene3D G3DSA:3.30.70.3460 68 155 1.8E-10 T 23-10-2018 APE_1497.1 b55b6ee3815dfb91bcd90eceffff95d7 324 SUPERFAMILY SSF46785 5 65 2.39E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 51 162 6.0E-10 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 Gene3D G3DSA:3.30.565.10 19 255 1.7E-66 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 Gene3D G3DSA:1.10.8.50 256 335 5.1E-20 T 23-10-2018 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 Pfam PF09239 Topoisomerase VI B subunit, transducer 337 492 2.0E-63 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 26 516 8.5E-220 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 PIRSF PIRSF006553 17 564 3.0E-204 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 SUPERFAMILY SSF54211 336 495 1.06E-60 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 335 544 7.0E-116 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 SUPERFAMILY SSF46946 256 328 8.83E-8 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 25 534 32.44 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 SUPERFAMILY SSF55874 36 253 1.19E-31 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 SMART SM00387 48 172 0.0062 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase APE_0706.1 47032a4b7263610ca078e6d7efb04434 568 Gene3D G3DSA:3.30.230.10 336 554 2.4E-70 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_0892.1 ddb2159a9a193ae7984272c728916741 355 SMART SM00382 17 184 2.7E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0892.1 ddb2159a9a193ae7984272c728916741 355 Gene3D G3DSA:3.40.50.300 13 190 2.5E-15 T 23-10-2018 APE_0892.1 ddb2159a9a193ae7984272c728916741 355 Pfam PF07728 AAA domain (dynein-related subfamily) 21 174 5.3E-7 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 APE_0892.1 ddb2159a9a193ae7984272c728916741 355 SUPERFAMILY SSF52540 19 192 5.55E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0257a ec3d2f81a43651c2468021a4a3c42486 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 22 33 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0257a ec3d2f81a43651c2468021a4a3c42486 56 SUPERFAMILY SSF46548 11 50 9.07E-10 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_0257a ec3d2f81a43651c2468021a4a3c42486 56 Pfam PF00037 4Fe-4S binding domain 21 35 1.6E-4 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_0257a ec3d2f81a43651c2468021a4a3c42486 56 Gene3D G3DSA:1.10.1060.10 8 55 7.6E-7 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_1209b c5675235b47f257c71a9198021570061 141 Gene3D G3DSA:3.40.50.1010 4 141 3.4E-12 T 23-10-2018 APE_1209b c5675235b47f257c71a9198021570061 141 Pfam PF01850 PIN domain 5 140 5.5E-17 T 23-10-2018 IPR002716 PIN domain APE_1209b c5675235b47f257c71a9198021570061 141 SUPERFAMILY SSF88723 3 140 1.28E-14 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 Gene3D G3DSA:3.10.580.10 200 339 1.4E-31 T 23-10-2018 APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 SUPERFAMILY SSF54631 198 331 1.46E-28 T 23-10-2018 APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 Gene3D G3DSA:3.10.580.10 58 198 6.1E-26 T 23-10-2018 APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 Pfam PF00571 CBS domain 284 333 5.2E-10 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 Pfam PF00571 CBS domain 204 258 1.6E-9 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 Pfam PF00571 CBS domain 141 196 1.9E-9 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 Pfam PF00571 CBS domain 60 115 7.0E-7 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 SMART SM00116 148 196 1.3 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 SMART SM00116 211 260 5.1E-8 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 SMART SM00116 288 335 8.4E-12 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 SMART SM00116 66 116 0.0051 T 23-10-2018 IPR000644 CBS domain APE_0233 dc2ebdc4c784b5968b37ec07ceaa3097 340 SUPERFAMILY SSF54631 59 196 1.39E-23 T 23-10-2018 APE_0890a.1 6d225f5d98364790b6a65291e5d4480b 79 Pfam PF03683 Uncharacterised protein family (UPF0175) 18 76 5.9E-17 T 23-10-2018 IPR005368 Uncharacterised protein family UPF0175 APE_0436a 48904e6751298d8d39801f540efee5da 73 Pfam PF01667 Ribosomal protein S27 19 69 5.4E-21 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0436a 48904e6751298d8d39801f540efee5da 73 Gene3D G3DSA:2.20.25.100 20 72 3.1E-19 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily APE_0436a 48904e6751298d8d39801f540efee5da 73 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 13 72 20.445 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0436a 48904e6751298d8d39801f540efee5da 73 ProSitePatterns PS01168 Ribosomal protein S27e signature. 27 59 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0436a 48904e6751298d8d39801f540efee5da 73 SUPERFAMILY SSF57829 19 71 3.48E-18 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APE_0796.1 a0cc3f3b486a521bdd465bc58839c893 230 Gene3D G3DSA:3.40.30.10 74 218 7.4E-19 T 23-10-2018 APE_0796.1 a0cc3f3b486a521bdd465bc58839c893 230 SUPERFAMILY SSF52833 80 225 1.54E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_0796.1 a0cc3f3b486a521bdd465bc58839c893 230 Pfam PF02630 SCO1/SenC 79 199 6.3E-6 T 23-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_2165 636b6ae04d9c77b21cf2d3d24dd2147e 197 Pfam PF02374 Anion-transporting ATPase 3 175 2.6E-27 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 APE_2165 636b6ae04d9c77b21cf2d3d24dd2147e 197 Gene3D G3DSA:3.40.50.300 1 191 7.2E-36 T 23-10-2018 APE_2165 636b6ae04d9c77b21cf2d3d24dd2147e 197 SUPERFAMILY SSF52540 3 188 2.07E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0741 476f49687d72322d0729486dff2badb5 214 SUPERFAMILY SSF54719 92 204 3.14E-43 T 23-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 SUPERFAMILY SSF46609 4 92 3.4E-30 T 23-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 6 87 7.8E-29 T 23-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 96 198 8.5E-36 T 23-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 PIRSF PIRSF000349 1 208 2.0E-78 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 PRINTS PR01703 Manganese superoxide dismutase signature 10 21 6.9E-21 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 PRINTS PR01703 Manganese superoxide dismutase signature 31 44 6.9E-21 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 PRINTS PR01703 Manganese superoxide dismutase signature 70 83 6.9E-21 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 PRINTS PR01703 Manganese superoxide dismutase signature 125 133 6.9E-21 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 6.9E-21 T 23-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 23-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 Gene3D G3DSA:1.10.287.990 24 87 1.9E-26 T 23-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_0741 476f49687d72322d0729486dff2badb5 214 Gene3D G3DSA:2.40.500.20 88 214 2.5E-51 T 23-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 4.0E-16 T 23-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 SUPERFAMILY SSF47203 238 400 9.67E-39 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 Gene3D G3DSA:1.20.140.10 245 405 4.1E-33 T 23-10-2018 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 226 5.0E-14 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 PIRSF PIRSF016578 19 134 1.1E-4 T 23-10-2018 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 PIRSF PIRSF016578 226 373 1.9E-11 T 23-10-2018 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 Gene3D G3DSA:1.10.540.10 1 121 5.1E-21 T 23-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 Gene3D G3DSA:2.40.110.10 124 244 1.5E-23 T 23-10-2018 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 397 8.4E-32 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_2354 4ed7ed0d9ef7c8c929a9b3ddc355ade4 405 SUPERFAMILY SSF56645 2 239 4.19E-46 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APE_0073.1 311c267bebfa6a73dc8fe486bf44aaa0 596 Pfam PF01170 Putative RNA methylase family UPF0020 75 134 6.7E-5 T 23-10-2018 IPR000241 Putative RNA methylase domain APE_0073.1 311c267bebfa6a73dc8fe486bf44aaa0 596 SUPERFAMILY SSF53335 76 117 1.66E-8 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0073.1 311c267bebfa6a73dc8fe486bf44aaa0 596 SUPERFAMILY SSF53335 78 494 1.66E-5 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0073.1 311c267bebfa6a73dc8fe486bf44aaa0 596 Gene3D G3DSA:3.40.50.150 70 154 1.1E-7 T 23-10-2018 APE_0309.1 d48ae2dc0fa74afee256449ea773846e 367 Gene3D G3DSA:3.30.9.10 86 322 9.8E-55 T 23-10-2018 APE_0309.1 d48ae2dc0fa74afee256449ea773846e 367 Gene3D G3DSA:3.50.50.60 5 353 9.8E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0309.1 d48ae2dc0fa74afee256449ea773846e 367 SUPERFAMILY SSF51905 4 361 2.46E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0309.1 d48ae2dc0fa74afee256449ea773846e 367 Pfam PF01266 FAD dependent oxidoreductase 5 358 8.3E-40 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 APE_2324.1 d1ccd7a16f416760b7a2eeeaae3242f8 94 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 21.52 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2324.1 d1ccd7a16f416760b7a2eeeaae3242f8 94 SUPERFAMILY SSF50447 4 87 3.88E-18 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_2324.1 d1ccd7a16f416760b7a2eeeaae3242f8 94 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 3.0E-30 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2324.1 d1ccd7a16f416760b7a2eeeaae3242f8 94 Gene3D G3DSA:2.40.10.190 2 91 5.6E-18 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2324.1 d1ccd7a16f416760b7a2eeeaae3242f8 94 Pfam PF01247 Ribosomal protein L35Ae 4 87 1.6E-9 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0788.1 ca8bded953759d18c55fb94b92a7d48a 197 SUPERFAMILY SSF52972 3 170 1.96E-35 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APE_0788.1 ca8bded953759d18c55fb94b92a7d48a 197 Hamap MF_00648 Non-canonical purine NTP phosphatase. 3 172 27.93 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase APE_0788.1 ca8bded953759d18c55fb94b92a7d48a 197 Gene3D G3DSA:3.90.950.10 1 177 3.6E-37 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like APE_0788.1 ca8bded953759d18c55fb94b92a7d48a 197 Pfam PF01931 Protein of unknown function DUF84 8 169 1.6E-40 T 23-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 APE_2267.1 d3ffe3866117105058a9186a64a816cb 459 Gene3D G3DSA:3.90.1150.10 6 382 1.8E-91 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2267.1 d3ffe3866117105058a9186a64a816cb 459 SUPERFAMILY SSF53383 6 364 1.53E-82 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2267.1 d3ffe3866117105058a9186a64a816cb 459 Gene3D G3DSA:3.40.640.10 41 297 1.8E-91 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2267.1 d3ffe3866117105058a9186a64a816cb 459 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 84 311 3.7E-18 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 APE_1501.1 22d17b80c747ca01c42e50df795b2eaf 133 SUPERFAMILY SSF55298 9 129 1.88E-42 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APE_1501.1 22d17b80c747ca01c42e50df795b2eaf 133 Pfam PF01042 Endoribonuclease L-PSP 12 127 1.1E-39 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 APE_1501.1 22d17b80c747ca01c42e50df795b2eaf 133 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 8 127 1.3E-47 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 APE_1501.1 22d17b80c747ca01c42e50df795b2eaf 133 Gene3D G3DSA:3.30.1330.40 11 133 8.3E-55 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 APE_0505 64f1fc84a0aa3db66c02dee7119d4522 136 Pfam PF03966 Trm112p-like protein 4 88 1.5E-17 T 23-10-2018 IPR005651 Trm112-like APE_0505 64f1fc84a0aa3db66c02dee7119d4522 136 SUPERFAMILY SSF158997 6 102 9.81E-12 T 23-10-2018 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 SUPERFAMILY SSF55486 6 497 5.25E-109 T 23-10-2018 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 Gene3D G3DSA:1.10.1370.30 2 498 1.5E-184 T 23-10-2018 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 381 398 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 231 247 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 404 425 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 335 354 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 248 267 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 295 311 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 449 467 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 268 287 3.1E-73 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 497 1.8E-103 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_1775.1 a1fa960d9cc8c23e0a6781463e867682 500 PIRSF PIRSF006615 5 500 1.2E-198 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 APE_0763.1 1134a76cf936c83050cd751dec8a735a 322 Gene3D G3DSA:3.40.50.720 3 283 7.1E-23 T 23-10-2018 APE_0763.1 1134a76cf936c83050cd751dec8a735a 322 SUPERFAMILY SSF51735 3 252 7.27E-24 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0763.1 1134a76cf936c83050cd751dec8a735a 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 186 3.1E-11 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 Gene3D G3DSA:3.10.580.10 139 276 7.7E-32 T 23-10-2018 APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 SUPERFAMILY SSF54631 22 131 8.97E-19 T 23-10-2018 APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 SMART SM00116 84 132 1.7 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 SMART SM00116 149 197 1.4E-6 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 SMART SM00116 220 270 9.4E-7 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 SMART SM00116 22 70 0.0072 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 SUPERFAMILY SSF54631 137 269 3.12E-30 T 23-10-2018 APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 Gene3D G3DSA:3.10.580.10 17 137 5.7E-16 T 23-10-2018 APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 Pfam PF00571 CBS domain 143 194 8.8E-10 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 Pfam PF00571 CBS domain 213 268 1.8E-12 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 Pfam PF00571 CBS domain 22 66 6.1E-7 T 23-10-2018 IPR000644 CBS domain APE_0234 fd1d77c8455d65cf2de30e832f3926fa 278 Pfam PF00571 CBS domain 79 126 2.6E-5 T 23-10-2018 IPR000644 CBS domain APE_1530.1 fa12610348050651127f98a465968f2d 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 19 442 5.3E-136 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 APE_1530.1 fa12610348050651127f98a465968f2d 450 SMART SM00729 154 374 2.4E-56 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_1530.1 fa12610348050651127f98a465968f2d 450 Gene3D G3DSA:3.40.50.12160 19 144 3.1E-19 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily APE_1530.1 fa12610348050651127f98a465968f2d 450 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 20 435 7.3E-116 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 APE_1530.1 fa12610348050651127f98a465968f2d 450 SUPERFAMILY SSF102114 154 384 3.66E-51 T 23-10-2018 APE_1530.1 fa12610348050651127f98a465968f2d 450 Pfam PF00919 Uncharacterized protein family UPF0004 20 110 2.9E-20 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 APE_1530.1 fa12610348050651127f98a465968f2d 450 Pfam PF04055 Radical SAM superfamily 160 333 3.8E-28 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1530.1 fa12610348050651127f98a465968f2d 450 Pfam PF01938 TRAM domain 386 444 6.8E-13 T 23-10-2018 IPR002792 TRAM domain APE_1530.1 fa12610348050651127f98a465968f2d 450 Gene3D G3DSA:3.80.30.20 153 388 1.3E-71 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APE_2379a 0268f3a2710b2fc8d9b52e2c254aee01 63 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 56 27.292 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_2379a 0268f3a2710b2fc8d9b52e2c254aee01 63 SMART SM00746 7 45 1.4E-12 T 23-10-2018 IPR011017 TRASH domain APE_2379a 0268f3a2710b2fc8d9b52e2c254aee01 63 Gene3D G3DSA:2.30.170.20 2 62 9.4E-26 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily APE_2379a 0268f3a2710b2fc8d9b52e2c254aee01 63 Pfam PF01246 Ribosomal protein L24e 3 59 8.1E-19 T 23-10-2018 IPR000988 Ribosomal protein L24e-related APE_2379a 0268f3a2710b2fc8d9b52e2c254aee01 63 SUPERFAMILY SSF57716 5 55 2.28E-15 T 23-10-2018 APE_1450.1 179bae969ad186808c7d11b06bf55239 211 SUPERFAMILY SSF89550 16 205 5.1E-22 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 APE_1450.1 179bae969ad186808c7d11b06bf55239 211 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 6 210 16.051 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 APE_1450.1 179bae969ad186808c7d11b06bf55239 211 Gene3D G3DSA:3.20.20.140 48 205 5.2E-16 T 23-10-2018 APE_1450.1 179bae969ad186808c7d11b06bf55239 211 Pfam PF01876 RNase P subunit p30 5 193 8.9E-12 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 APE_0201.1 0d487939f8ebff709819ea4580513daa 368 Gene3D G3DSA:3.50.50.60 9 119 3.7E-8 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0201.1 0d487939f8ebff709819ea4580513daa 368 Gene3D G3DSA:3.50.50.60 123 344 3.2E-13 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0201.1 0d487939f8ebff709819ea4580513daa 368 SUPERFAMILY SSF51905 13 291 6.15E-13 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0581.1 b45799b8cbd75da24b35e93e3e393165 270 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 13 266 1.1E-128 T 23-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 APE_0581.1 b45799b8cbd75da24b35e93e3e393165 270 Gene3D G3DSA:3.20.20.70 1 270 1.1E-111 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0581.1 b45799b8cbd75da24b35e93e3e393165 270 Pfam PF00793 DAHP synthetase I family 22 260 6.5E-82 T 23-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 APE_0581.1 b45799b8cbd75da24b35e93e3e393165 270 SUPERFAMILY SSF51569 8 266 2.29E-98 T 23-10-2018 APE_1045.1 3502064282d9f7740c391e0582bd99a5 319 Pfam PF01435 Peptidase family M48 70 308 1.7E-36 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 APE_1045.1 3502064282d9f7740c391e0582bd99a5 319 Hamap MF_00188 Protease HtpX [htpX]. 1 309 28.087 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 APE_1045.1 3502064282d9f7740c391e0582bd99a5 319 Gene3D G3DSA:3.30.2010.10 60 150 5.3E-24 T 23-10-2018 APE_0459 a41bd72c7e0a40a3027dca43e2204635 112 Gene3D G3DSA:1.10.10.10 9 83 2.8E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0459 a41bd72c7e0a40a3027dca43e2204635 112 SMART SM00419 20 68 3.2E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 APE_0459 a41bd72c7e0a40a3027dca43e2204635 112 SUPERFAMILY SSF46785 11 71 1.25E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2174 57be9150edc7e09480ffd2c06c318caf 108 SMART SM00649 1 76 5.0E-4 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 APE_2174 57be9150edc7e09480ffd2c06c318caf 108 SUPERFAMILY SSF46906 9 80 1.7E-18 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily APE_2174 57be9150edc7e09480ffd2c06c318caf 108 Gene3D G3DSA:1.10.10.250 11 101 1.2E-30 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily APE_2174 57be9150edc7e09480ffd2c06c318caf 108 Pfam PF00298 Ribosomal protein L11, RNA binding domain 9 75 1.2E-18 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 APE_2174 57be9150edc7e09480ffd2c06c318caf 108 ProSitePatterns PS00359 Ribosomal protein L11 signature. 62 77 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0815.1 5f4e577e4acf4df43c464fb15ba8ee7e 277 SUPERFAMILY SSF53335 7 274 8.98E-53 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0815.1 5f4e577e4acf4df43c464fb15ba8ee7e 277 Gene3D G3DSA:3.40.50.150 14 275 3.1E-52 T 23-10-2018 APE_0815.1 5f4e577e4acf4df43c464fb15ba8ee7e 277 Pfam PF02475 Met-10+ like-protein 15 217 1.4E-49 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 SMART SM00350 108 605 7.2E-209 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 332 347 4.2E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 444 456 4.2E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 471 479 4.2E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 392 406 4.2E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 420 433 4.2E-30 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 SUPERFAMILY SSF52540 301 601 2.19E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 SMART SM00382 333 486 0.0012 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Gene3D G3DSA:3.30.1640.10 7 106 1.6E-23 T 23-10-2018 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Gene3D G3DSA:3.40.50.300 275 609 1.7E-135 T 23-10-2018 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Gene3D G3DSA:2.20.28.10 143 190 2.7E-12 T 23-10-2018 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Pfam PF00493 MCM2/3/5 family 278 604 1.6E-134 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 ProSitePatterns PS00847 MCM family signature. 400 408 - T 23-10-2018 IPR018525 Mini-chromosome maintenance, conserved site GO:0003677|GO:0005524|GO:0006260 Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Gene3D G3DSA:1.10.10.10 610 697 5.6E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 SUPERFAMILY SSF50249 17 260 2.4E-61 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Pfam PF14551 MCM N-terminal domain 16 97 1.9E-19 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 APE_0188.1 86f4413a799b0a213c37b05b7b48dc7f 697 Pfam PF17207 MCM OB domain 112 241 9.2E-35 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 APE_0966.1 4aa959b37c97ee9569e845387d71e425 724 SUPERFAMILY SSF56300 169 426 2.71E-35 T 23-10-2018 APE_0966.1 4aa959b37c97ee9569e845387d71e425 724 Gene3D G3DSA:3.60.21.10 149 439 3.1E-29 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_0966.1 4aa959b37c97ee9569e845387d71e425 724 Pfam PF00149 Calcineurin-like phosphoesterase 168 374 1.1E-14 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APE_0396.1 7444806d68708f07bf9014c39688fed7 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 23-10-2018 IPR020845 AMP-binding, conserved site APE_0396.1 7444806d68708f07bf9014c39688fed7 555 Gene3D G3DSA:3.30.300.310 439 551 9.5E-34 T 23-10-2018 APE_0396.1 7444806d68708f07bf9014c39688fed7 555 Pfam PF00501 AMP-binding enzyme 38 443 9.9E-100 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_0396.1 7444806d68708f07bf9014c39688fed7 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 535 3.6E-22 T 23-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain APE_0396.1 7444806d68708f07bf9014c39688fed7 555 SUPERFAMILY SSF56801 10 550 4.58E-143 T 23-10-2018 APE_0396.1 7444806d68708f07bf9014c39688fed7 555 Gene3D G3DSA:3.40.50.12780 9 438 1.2E-118 T 23-10-2018 APE_2154.1 bd27583eb5071082ddeb9161cc9f90b5 285 TIGRFAM TIGR01912 TatC-Arch: Sec-independent protein translocase TatC 35 273 3.8E-77 T 23-10-2018 IPR011532 Sec-independent protein translocase TatC, archaeal APE_2154.1 bd27583eb5071082ddeb9161cc9f90b5 285 Pfam PF00902 Sec-independent protein translocase protein (TatC) 25 256 2.4E-38 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APE_2154.1 bd27583eb5071082ddeb9161cc9f90b5 285 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 114 132 7.7E-16 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APE_2154.1 bd27583eb5071082ddeb9161cc9f90b5 285 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 21 48 7.7E-16 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APE_2154.1 bd27583eb5071082ddeb9161cc9f90b5 285 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 132 158 7.7E-16 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APE_2154.1 bd27583eb5071082ddeb9161cc9f90b5 285 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 187 215 7.7E-16 T 23-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 APE_0555.1 84e6ab8823140d1b1b129d68a6fc44e4 243 Pfam PF00588 SpoU rRNA Methylase family 4 152 1.3E-28 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 APE_0555.1 84e6ab8823140d1b1b129d68a6fc44e4 243 PIRSF PIRSF004808 1 233 3.3E-61 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 APE_0555.1 84e6ab8823140d1b1b129d68a6fc44e4 243 SUPERFAMILY SSF75217 3 159 6.8E-31 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_0555.1 84e6ab8823140d1b1b129d68a6fc44e4 243 Gene3D G3DSA:3.40.1280.10 1 160 2.4E-43 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 Gene3D G3DSA:3.40.30.10 1 121 1.0E-37 T 23-10-2018 APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 Gene3D G3DSA:3.40.30.10 124 225 1.8E-27 T 23-10-2018 APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 9 223 1.1E-81 T 23-10-2018 IPR011903 Glutaredoxin-like domain APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 SUPERFAMILY SSF52833 9 121 1.68E-11 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 Pfam PF13192 Thioredoxin domain 142 219 3.3E-16 T 23-10-2018 IPR012336 Thioredoxin-like fold APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 Pfam PF13192 Thioredoxin domain 28 113 2.3E-14 T 23-10-2018 IPR012336 Thioredoxin-like fold APE_0775 dca78390321f7a2f42b370fbb2de6b1f 243 SUPERFAMILY SSF52833 126 222 4.32E-17 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 Pfam PF08264 Anticodon-binding domain of tRNA 623 772 1.4E-22 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 SUPERFAMILY SSF50677 200 351 1.96E-43 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 Gene3D G3DSA:3.40.50.620 29 545 3.9E-194 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 SUPERFAMILY SSF47323 596 789 6.35E-31 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 Gene3D G3DSA:3.90.740.10 185 352 3.9E-194 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 PRINTS PR00986 Valyl-tRNA synthetase signature 45 56 2.1E-12 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 PRINTS PR00986 Valyl-tRNA synthetase signature 240 257 2.1E-12 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 PRINTS PR00986 Valyl-tRNA synthetase signature 465 486 2.1E-12 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 PRINTS PR00986 Valyl-tRNA synthetase signature 496 514 2.1E-12 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 22 583 2.0E-110 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 SUPERFAMILY SSF52374 19 594 1.97E-107 T 23-10-2018 APE_1805.1 cd5f7dfee04f6d57b6cb81bfb7529fd8 823 Gene3D G3DSA:1.10.730.10 19 754 3.9E-194 T 23-10-2018 APE_2078 dd6fee4247662bd87ebc98ef27bda2d5 437 SUPERFAMILY SSF143968 287 420 3.66E-41 T 23-10-2018 APE_2078 dd6fee4247662bd87ebc98ef27bda2d5 437 Gene3D G3DSA:3.40.1670.10 297 409 1.1E-36 T 23-10-2018 APE_2078 dd6fee4247662bd87ebc98ef27bda2d5 437 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 15 410 9.5E-86 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 APE_2078 dd6fee4247662bd87ebc98ef27bda2d5 437 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 16 386 7.3E-78 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 APE_2078 dd6fee4247662bd87ebc98ef27bda2d5 437 SUPERFAMILY SSF50475 10 280 4.32E-54 T 23-10-2018 APE_2617b cf72cfb375fbd52a21b3346ea69c0985 80 Gene3D G3DSA:3.40.50.1010 4 78 1.3E-5 T 23-10-2018 APE_2617b cf72cfb375fbd52a21b3346ea69c0985 80 SUPERFAMILY SSF88723 22 76 1.96E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_2617b cf72cfb375fbd52a21b3346ea69c0985 80 Pfam PF01850 PIN domain 19 77 2.1E-12 T 23-10-2018 IPR002716 PIN domain APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 Gene3D G3DSA:3.40.50.720 4 325 2.4E-101 T 23-10-2018 APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 232 248 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 Gene3D G3DSA:3.40.50.720 104 299 2.4E-101 T 23-10-2018 APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 203 225 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 SUPERFAMILY SSF52283 4 143 2.34E-27 T 23-10-2018 APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 298 5.7E-58 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 330 9.1E-27 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 APE_2507.1 2234520cf8c3e3c2087abeac410e794e 333 SUPERFAMILY SSF51735 106 299 2.78E-56 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1695.1 14d6135929f53c934066028138c55aed 375 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 371 38.972 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 APE_1695.1 14d6135929f53c934066028138c55aed 375 SUPERFAMILY SSF101790 280 370 2.13E-21 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal APE_1695.1 14d6135929f53c934066028138c55aed 375 Gene3D G3DSA:3.30.1360.120 2 369 2.5E-92 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 APE_1695.1 14d6135929f53c934066028138c55aed 375 PIRSF PIRSF006487 1 374 1.4E-84 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 APE_1695.1 14d6135929f53c934066028138c55aed 375 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 272 363 7.3E-20 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 APE_1695.1 14d6135929f53c934066028138c55aed 375 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 249 8.5E-69 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain APE_1695.1 14d6135929f53c934066028138c55aed 375 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 369 4.0E-77 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 APE_1695.1 14d6135929f53c934066028138c55aed 375 SUPERFAMILY SSF103025 2 287 5.65E-72 T 23-10-2018 APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 Gene3D G3DSA:3.40.640.10 72 341 3.5E-159 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 Gene3D G3DSA:3.90.1150.10 17 438 3.5E-159 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 SUPERFAMILY SSF53383 29 444 1.55E-132 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 Pfam PF00202 Aminotransferase class-III 37 442 2.5E-122 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 PIRSF PIRSF000521 139 445 5.6E-47 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 PIRSF PIRSF000521 1 144 1.5E-10 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_0457 e8510f3ce692bdf9d7bc9cbab6a36262 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 9 339 38.188 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 12 25 2.5E-37 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 2.5E-37 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 2.5E-37 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 262 271 2.5E-37 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 135 147 2.5E-37 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 157 178 2.5E-37 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 Pfam PF00814 Glycoprotease family 39 305 1.3E-70 T 23-10-2018 IPR000905 Gcp-like domain APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 Gene3D G3DSA:3.30.420.40 11 313 3.6E-79 T 23-10-2018 APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 12 305 1.8E-67 T 23-10-2018 IPR017861 Kae1/TsaD family APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 11 338 7.3E-140 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 SUPERFAMILY SSF53067 10 306 4.1E-22 T 23-10-2018 APE_1135 d62950901a1fb7dcdcdf27ec9518bd54 349 Gene3D G3DSA:3.30.420.40 133 292 3.6E-79 T 23-10-2018 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 9 56 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 1 198 34.546 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 PRINTS PR00141 Proteasome component signature 146 157 3.2E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 PRINTS PR00141 Proteasome component signature 135 146 3.2E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 PRINTS PR00141 Proteasome component signature 171 182 3.2E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 PRINTS PR00141 Proteasome component signature 13 28 3.2E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 Pfam PF00227 Proteasome subunit 4 184 3.2E-52 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 SUPERFAMILY SSF56235 4 189 1.28E-57 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 Gene3D G3DSA:3.60.20.10 3 193 1.1E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal APE_0507.1 85e8485c8cf2965ce2eaea7e1f4a1ddd 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 5 187 4.8E-70 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 SUPERFAMILY SSF55920 150 369 4.97E-70 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 SUPERFAMILY SSF53092 3 136 6.28E-6 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 Pfam PF01321 Creatinase/Prolidase N-terminal domain 9 150 1.7E-9 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 Gene3D G3DSA:3.40.350.10 8 149 3.5E-8 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 Gene3D G3DSA:3.90.230.10 150 373 3.9E-72 T 23-10-2018 APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 306 318 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site APE_0526.1 a26c42c8384b8538280bedb9d2f1fa40 373 Pfam PF00557 Metallopeptidase family M24 159 360 6.7E-61 T 23-10-2018 IPR000994 Peptidase M24 APE_1223.1 112b014b6e93c70ea7d2ea9db2a29e30 389 SUPERFAMILY SSF53686 10 377 3.36E-85 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme APE_1223.1 112b014b6e93c70ea7d2ea9db2a29e30 389 Gene3D G3DSA:3.40.50.1100 158 383 3.0E-63 T 23-10-2018 APE_1223.1 112b014b6e93c70ea7d2ea9db2a29e30 389 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 355 1.3E-59 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme APE_1223.1 112b014b6e93c70ea7d2ea9db2a29e30 389 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 42 60 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 APE_1223.1 112b014b6e93c70ea7d2ea9db2a29e30 389 Gene3D G3DSA:3.40.50.1100 20 54 3.3E-36 T 23-10-2018 APE_1223.1 112b014b6e93c70ea7d2ea9db2a29e30 389 Gene3D G3DSA:3.40.50.1100 55 131 3.3E-36 T 23-10-2018 APE_0554.1 f09b5a70fb3380b1b326ddcce0778d56 196 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 23 75 1.3E-4 T 23-10-2018 APE_0554.1 f09b5a70fb3380b1b326ddcce0778d56 196 SUPERFAMILY SSF53335 9 148 3.31E-15 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0554.1 f09b5a70fb3380b1b326ddcce0778d56 196 Gene3D G3DSA:3.40.50.150 15 196 3.0E-17 T 23-10-2018 APE_0554.1 f09b5a70fb3380b1b326ddcce0778d56 196 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 105 111 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APE_0532.1 97371bac04666c5d3151856856f8631d 247 SUPERFAMILY SSF52540 3 222 5.64E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0532.1 97371bac04666c5d3151856856f8631d 247 Gene3D G3DSA:3.40.50.300 1 233 1.1E-55 T 23-10-2018 APE_0532.1 97371bac04666c5d3151856856f8631d 247 Pfam PF00005 ABC transporter 18 162 3.3E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0532.1 97371bac04666c5d3151856856f8631d 247 SMART SM00382 27 210 2.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0957a 1f8cbe17611e1e8422f56e5e9502d56d 94 SMART SM00651 14 81 3.0E-19 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type APE_0957a 1f8cbe17611e1e8422f56e5e9502d56d 94 SUPERFAMILY SSF50182 12 83 5.29E-20 T 23-10-2018 IPR010920 LSM domain superfamily APE_0957a 1f8cbe17611e1e8422f56e5e9502d56d 94 Gene3D G3DSA:2.30.30.100 3 89 5.1E-21 T 23-10-2018 APE_0957a 1f8cbe17611e1e8422f56e5e9502d56d 94 Pfam PF01423 LSM domain 15 80 2.1E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type APE_2161 3c5423818fc2fc0ae4f3e524f02602c1 489 Gene3D G3DSA:3.20.20.140 56 452 1.2E-80 T 23-10-2018 APE_2161 3c5423818fc2fc0ae4f3e524f02602c1 489 Gene3D G3DSA:3.10.310.70 74 178 1.2E-80 T 23-10-2018 APE_2161 3c5423818fc2fc0ae4f3e524f02602c1 489 SUPERFAMILY SSF51556 55 445 4.17E-28 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_2161 3c5423818fc2fc0ae4f3e524f02602c1 489 Gene3D G3DSA:2.30.40.10 52 466 1.2E-80 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 APE_2161 3c5423818fc2fc0ae4f3e524f02602c1 489 Pfam PF07969 Amidohydrolase family 52 472 7.1E-58 T 23-10-2018 IPR013108 Amidohydrolase 3 APE_1686.1 bcb5e8e69a193f5816b1e24ef2aa38b4 161 SUPERFAMILY SSF52242 5 142 1.7E-50 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 APE_1686.1 bcb5e8e69a193f5816b1e24ef2aa38b4 161 Gene3D G3DSA:3.40.50.280 1 161 3.0E-74 T 23-10-2018 APE_1686.1 bcb5e8e69a193f5816b1e24ef2aa38b4 161 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 17 145 2.5E-50 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 APE_1686.1 bcb5e8e69a193f5816b1e24ef2aa38b4 161 Pfam PF02310 B12 binding domain 20 114 7.9E-22 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 APE_1586b 14244ac7dbdc4483945e1d32cac64b89 35 Gene3D G3DSA:1.20.140.10 1 35 9.0E-6 T 23-10-2018 APE_1586b 14244ac7dbdc4483945e1d32cac64b89 35 SUPERFAMILY SSF47203 7 35 3.72E-5 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_1239.1 161cdc7f0fac09cf8055ffe361ede320 199 Pfam PF01930 Domain of unknown function DUF83 4 189 5.2E-10 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 APE_1239.1 161cdc7f0fac09cf8055ffe361ede320 199 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 3 190 4.7E-49 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 APE_1239.1 161cdc7f0fac09cf8055ffe361ede320 199 Gene3D G3DSA:3.90.320.10 6 191 2.0E-7 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal APE_1999 8f95882e009ba180703fc8480a2e2988 382 SUPERFAMILY SSF116726 136 178 1.7E-5 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 APE_1999 8f95882e009ba180703fc8480a2e2988 382 SUPERFAMILY SSF109755 10 290 4.5E-12 T 23-10-2018 APE_1999 8f95882e009ba180703fc8480a2e2988 382 Gene3D G3DSA:1.20.58.220 10 114 1.7E-7 T 23-10-2018 IPR038078 PhoU-like domain superfamily APE_0023.1 3866fbce83be0acc1a64463f81ebeb8e 172 SUPERFAMILY SSF56784 7 141 9.71E-10 T 23-10-2018 IPR036412 HAD-like superfamily APE_0023.1 3866fbce83be0acc1a64463f81ebeb8e 172 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 7 157 2.9E-30 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 APE_0023.1 3866fbce83be0acc1a64463f81ebeb8e 172 Gene3D G3DSA:3.40.50.1000 5 163 1.0E-16 T 23-10-2018 IPR023214 HAD superfamily APE_0023.1 3866fbce83be0acc1a64463f81ebeb8e 172 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 7 138 1.0E-9 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC APE_1461.1 cc4ad3661b3b97f6292d3685f4c44eee 270 Pfam PF00696 Amino acid kinase family 7 246 1.6E-35 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APE_1461.1 cc4ad3661b3b97f6292d3685f4c44eee 270 SUPERFAMILY SSF53633 6 269 1.54E-41 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1461.1 cc4ad3661b3b97f6292d3685f4c44eee 270 Gene3D G3DSA:3.40.1160.10 2 270 8.5E-49 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1461.1 cc4ad3661b3b97f6292d3685f4c44eee 270 PIRSF PIRSF000728 2 270 1.2E-61 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APE_1461.1 cc4ad3661b3b97f6292d3685f4c44eee 270 TIGRFAM TIGR00761 argB: acetylglutamate kinase 7 250 1.3E-45 T 23-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 APE_1461.1 cc4ad3661b3b97f6292d3685f4c44eee 270 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 6 268 49.123 T 23-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 APE_2617.1 f6ac1463c695673e0d7d04ac2fc44ec0 147 Gene3D G3DSA:3.40.50.1010 5 136 1.0E-8 T 23-10-2018 APE_2617.1 f6ac1463c695673e0d7d04ac2fc44ec0 147 SMART SM00670 4 125 4.5E-6 T 23-10-2018 IPR002716 PIN domain APE_2617.1 f6ac1463c695673e0d7d04ac2fc44ec0 147 SUPERFAMILY SSF88723 4 143 2.8E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_2617.1 f6ac1463c695673e0d7d04ac2fc44ec0 147 Pfam PF01850 PIN domain 7 126 3.1E-9 T 23-10-2018 IPR002716 PIN domain APE_2516 06d81184e38b5091e54879cb8282ce5a 323 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 26 319 5.2E-96 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 APE_2516 06d81184e38b5091e54879cb8282ce5a 323 SMART SM00382 38 229 1.1E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2516 06d81184e38b5091e54879cb8282ce5a 323 Gene3D G3DSA:3.40.50.300 3 243 1.2E-61 T 23-10-2018 APE_2516 06d81184e38b5091e54879cb8282ce5a 323 Pfam PF00005 ABC transporter 29 173 7.7E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2516 06d81184e38b5091e54879cb8282ce5a 323 Pfam PF13732 Domain of unknown function (DUF4162) 227 317 1.4E-6 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 APE_2516 06d81184e38b5091e54879cb8282ce5a 323 SUPERFAMILY SSF52540 24 234 4.17E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0373 cde90932296629d76ba2450e947a0409 236 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 20 199 6.6E-43 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 APE_0373 cde90932296629d76ba2450e947a0409 236 Pfam PF12705 PD-(D/E)XK nuclease superfamily 73 198 6.1E-7 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type APE_0373 cde90932296629d76ba2450e947a0409 236 Pfam PF12705 PD-(D/E)XK nuclease superfamily 20 68 8.4E-5 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type APE_0373 cde90932296629d76ba2450e947a0409 236 Gene3D G3DSA:3.90.320.10 24 201 2.9E-7 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal APE_2538 5c84e6dc8f197eb2f4100c1bd8ba0440 559 Pfam PF03553 Na+/H+ antiporter family 161 510 3.6E-96 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 SUPERFAMILY SSF54768 49 120 2.09E-22 T 23-10-2018 APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 ProSitePatterns PS00585 Ribosomal protein S5 signature. 72 104 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 Pfam PF03719 Ribosomal protein S5, C-terminal domain 141 208 1.2E-23 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 Gene3D G3DSA:3.30.160.770 13 117 2.4E-41 T 23-10-2018 APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 7 207 49.569 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 9 217 2.1E-109 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 SUPERFAMILY SSF54211 133 212 9.36E-22 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 Gene3D G3DSA:3.30.230.10 118 214 8.6E-36 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_0346 c557aeda74a38ed9146c7076f53bfeb8 218 Pfam PF00333 Ribosomal protein S5, N-terminal domain 55 119 6.0E-26 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 APE_1363.1 8491df5b5a84579e116228f2eeab90ba 273 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 73 265 6.1E-40 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 APE_2223 2a43558fb4d8116950ec58f2a4d13469 205 Gene3D G3DSA:3.90.550.10 1 196 3.7E-44 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_2223 2a43558fb4d8116950ec58f2a4d13469 205 SUPERFAMILY SSF53448 1 188 8.56E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_2223 2a43558fb4d8116950ec58f2a4d13469 205 Pfam PF12804 MobA-like NTP transferase domain 1 163 4.3E-29 T 23-10-2018 IPR025877 MobA-like NTP transferase APE_2493.1 0e45ecb886c9a9ad0da61f20d5303360 543 Pfam PF04055 Radical SAM superfamily 193 390 2.6E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_2493.1 0e45ecb886c9a9ad0da61f20d5303360 543 Gene3D G3DSA:3.80.30.20 187 420 9.8E-16 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APE_2493.1 0e45ecb886c9a9ad0da61f20d5303360 543 SUPERFAMILY SSF102114 178 393 1.26E-15 T 23-10-2018 APE_2493.1 0e45ecb886c9a9ad0da61f20d5303360 543 SMART SM00729 188 438 1.1E-11 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 29 40 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 Gene3D G3DSA:3.20.20.70 12 320 9.9E-61 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 SMART SM00729 23 227 1.5E-10 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 Pfam PF06463 Molybdenum Cofactor Synthesis C 196 323 3.4E-21 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 SUPERFAMILY SSF102114 16 310 3.4E-59 T 23-10-2018 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 Pfam PF04055 Radical SAM superfamily 29 189 3.2E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 14 326 41.309 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 APE_0478.1 438de5d6160bcdd49c3d07da354d6de8 367 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 14 323 3.0E-110 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 APE_0076.1 0697b6f17a992a785d2986270580c6bb 283 SUPERFAMILY SSF103481 51 140 9.94E-12 T 23-10-2018 APE_0076.1 0697b6f17a992a785d2986270580c6bb 283 Pfam PF00892 EamA-like transporter family 9 137 4.5E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_0076.1 0697b6f17a992a785d2986270580c6bb 283 Pfam PF00892 EamA-like transporter family 150 280 1.4E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_0076.1 0697b6f17a992a785d2986270580c6bb 283 SUPERFAMILY SSF103481 189 280 1.15E-13 T 23-10-2018 APE_2481.1 315ad5c45754972ebe58e9226f6b1d5a 389 Pfam PF07318 Protein of unknown function (DUF1464) 6 366 2.3E-125 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 APE_2481.1 315ad5c45754972ebe58e9226f6b1d5a 389 PIRSF PIRSF009433 1 385 3.6E-157 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 APE_2124.1 a99a6cc1ae3612d947f792e7c35959c6 465 Pfam PF02347 Glycine cleavage system P-protein 14 458 2.1E-108 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 APE_2124.1 a99a6cc1ae3612d947f792e7c35959c6 465 Gene3D G3DSA:3.40.640.10 91 363 2.2E-144 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2124.1 a99a6cc1ae3612d947f792e7c35959c6 465 SUPERFAMILY SSF53383 14 463 1.42E-100 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2124.1 a99a6cc1ae3612d947f792e7c35959c6 465 Gene3D G3DSA:3.90.1150.10 80 458 2.2E-144 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2124.1 a99a6cc1ae3612d947f792e7c35959c6 465 PIRSF PIRSF006815 3 463 2.6E-146 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 APE_2124.1 a99a6cc1ae3612d947f792e7c35959c6 465 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 462 49.292 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 APE_2563 f64dfbd7aa969f2a2e8b250bb365c194 210 Gene3D G3DSA:2.102.10.10 76 206 1.0E-30 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APE_2563 f64dfbd7aa969f2a2e8b250bb365c194 210 SUPERFAMILY SSF50022 81 204 8.25E-25 T 23-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 APE_2563 f64dfbd7aa969f2a2e8b250bb365c194 210 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 15 41 7.5E-4 T 23-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal APE_2563 f64dfbd7aa969f2a2e8b250bb365c194 210 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 80 204 9.1E-42 T 23-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 APE_2563 f64dfbd7aa969f2a2e8b250bb365c194 210 Pfam PF00355 Rieske [2Fe-2S] domain 84 174 1.3E-12 T 23-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 APE_1132a dbbb509c6afe3ac4ba0f3b303e06171e 63 SMART SM01402 11 56 3.9E-21 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 APE_1132a dbbb509c6afe3ac4ba0f3b303e06171e 63 Pfam PF01599 Ribosomal protein S27a 11 56 1.9E-14 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 APE_1132a dbbb509c6afe3ac4ba0f3b303e06171e 63 Gene3D G3DSA:2.20.25.660 1 62 1.4E-9 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 APE_1132a dbbb509c6afe3ac4ba0f3b303e06171e 63 SUPERFAMILY SSF57829 11 62 1.35E-14 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APE_1132a dbbb509c6afe3ac4ba0f3b303e06171e 63 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 11 59 17.171 T 23-10-2018 IPR022845 Ribosomal protein S27ae APE_0056.1 2e946e959515fea126c8cc509a16502e 250 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 23-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 APE_0056.1 2e946e959515fea126c8cc509a16502e 250 SUPERFAMILY SSF52096 5 248 1.07E-62 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APE_0056.1 2e946e959515fea126c8cc509a16502e 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 248 6.4E-45 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 APE_0056.1 2e946e959515fea126c8cc509a16502e 250 Gene3D G3DSA:3.90.226.10 3 250 5.5E-64 T 23-10-2018 APE_0352a 7eaa3907857eb925e20cec4a864cf3e0 54 Pfam PF00253 Ribosomal protein S14p/S29e 6 52 8.2E-12 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0352a 7eaa3907857eb925e20cec4a864cf3e0 54 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 54 17.007 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 APE_0352a 7eaa3907857eb925e20cec4a864cf3e0 54 Gene3D G3DSA:4.10.830.10 2 54 3.3E-20 T 23-10-2018 APE_0352a 7eaa3907857eb925e20cec4a864cf3e0 54 ProSitePatterns PS00527 Ribosomal protein S14 signature. 21 42 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0352a 7eaa3907857eb925e20cec4a864cf3e0 54 SUPERFAMILY SSF57716 7 47 1.64E-6 T 23-10-2018 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 Gene3D G3DSA:3.20.20.70 112 302 1.8E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 56 115 8.7E-5 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 SUPERFAMILY SSF54675 7 120 1.22E-29 T 23-10-2018 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 120 309 3.0E-24 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 SUPERFAMILY SSF51690 117 388 2.5E-73 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 Gene3D G3DSA:3.90.1170.20 1 111 2.1E-30 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 PIRSF PIRSF000484 15 74 0.76 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 APE_1273.1 e88ce089f3d9c5741c7c9ad54d6bfd85 390 PIRSF PIRSF000484 71 389 2.3E-56 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 APE_2130.1 6b8a76c7ce2f773d8aec08e0e07d8a27 430 Gene3D G3DSA:3.90.1150.10 10 420 2.1E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2130.1 6b8a76c7ce2f773d8aec08e0e07d8a27 430 Pfam PF00202 Aminotransferase class-III 35 414 1.2E-59 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 APE_2130.1 6b8a76c7ce2f773d8aec08e0e07d8a27 430 SUPERFAMILY SSF53383 29 423 5.09E-100 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2130.1 6b8a76c7ce2f773d8aec08e0e07d8a27 430 Gene3D G3DSA:3.40.640.10 70 316 2.1E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 SMART SM00487 31 251 2.9E-13 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 58 392 4.1E-46 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 Pfam PF00270 DEAD/DEAH box helicase 39 223 6.6E-20 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 Pfam PF00271 Helicase conserved C-terminal domain 267 363 3.2E-5 T 23-10-2018 IPR001650 Helicase, C-terminal APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 SUPERFAMILY SSF52540 53 373 9.41E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 Gene3D G3DSA:3.40.50.300 245 400 1.1E-12 T 23-10-2018 APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 SMART SM00490 279 364 0.0019 T 23-10-2018 IPR001650 Helicase, C-terminal APE_1232 893b661a9f75b96d3b611f1bccec3f7e 570 Gene3D G3DSA:3.40.50.300 22 229 2.7E-15 T 23-10-2018 APE_2227 842f25365e3e01bbf7fc198c534d02de 298 Gene3D G3DSA:3.40.50.720 126 268 2.0E-25 T 23-10-2018 APE_2227 842f25365e3e01bbf7fc198c534d02de 298 Pfam PF02625 XdhC and CoxI family 24 87 9.6E-16 T 23-10-2018 IPR003777 XdhC- CoxI APE_2227 842f25365e3e01bbf7fc198c534d02de 298 Pfam PF13478 XdhC Rossmann domain 128 262 1.5E-24 T 23-10-2018 IPR027051 XdhC Rossmann domain APE_1753.1 047b005ee340ee2c6d127c627967a0a2 187 Pfam PF13207 AAA domain 12 133 2.2E-16 T 23-10-2018 APE_1753.1 047b005ee340ee2c6d127c627967a0a2 187 Gene3D G3DSA:3.40.50.300 8 179 1.6E-34 T 23-10-2018 APE_1753.1 047b005ee340ee2c6d127c627967a0a2 187 Hamap MF_01111 UPF0200 protein . 8 182 29.734 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related APE_1753.1 047b005ee340ee2c6d127c627967a0a2 187 SUPERFAMILY SSF52540 8 166 2.45E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0273 951b574228dc82840c2d65891e2674c8 144 SMART SM00670 1 136 3.5E-27 T 23-10-2018 IPR002716 PIN domain APE_0273 951b574228dc82840c2d65891e2674c8 144 Pfam PF01850 PIN domain 3 139 1.6E-21 T 23-10-2018 IPR002716 PIN domain APE_0273 951b574228dc82840c2d65891e2674c8 144 SUPERFAMILY SSF88723 1 139 1.63E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0273 951b574228dc82840c2d65891e2674c8 144 Gene3D G3DSA:3.40.50.1010 2 141 1.7E-14 T 23-10-2018 APE_2018.1 ef1f22c2ec2186664b072f13ce901bb6 244 SUPERFAMILY SSF159659 10 232 4.97E-24 T 23-10-2018 APE_2018.1 ef1f22c2ec2186664b072f13ce901bb6 244 Pfam PF09754 PAC2 family 22 226 7.0E-30 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 APE_2018.1 ef1f22c2ec2186664b072f13ce901bb6 244 Gene3D G3DSA:3.40.50.10900 1 243 6.3E-40 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily APE_0979.1 ab9a2776b003ed67024bec5d4c4c8a9e 431 Gene3D G3DSA:3.90.1300.10 56 423 6.9E-35 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_0979.1 ab9a2776b003ed67024bec5d4c4c8a9e 431 SUPERFAMILY SSF75304 58 395 3.27E-39 T 23-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_0979.1 ab9a2776b003ed67024bec5d4c4c8a9e 431 Pfam PF01425 Amidase 86 198 8.8E-22 T 23-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 APE_0235.1 a270eab3a4e2d0c4dd19bb8b343ba0f8 309 Gene3D G3DSA:3.90.650.10 136 309 7.2E-21 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APE_0235.1 a270eab3a4e2d0c4dd19bb8b343ba0f8 309 Pfam PF00586 AIR synthase related protein, N-terminal domain 44 129 8.6E-9 T 23-10-2018 IPR016188 PurM-like, N-terminal domain APE_0235.1 a270eab3a4e2d0c4dd19bb8b343ba0f8 309 PIRSF PIRSF005303 1 309 1.1E-63 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 APE_0235.1 a270eab3a4e2d0c4dd19bb8b343ba0f8 309 SUPERFAMILY SSF56042 135 298 5.02E-15 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily APE_0235.1 a270eab3a4e2d0c4dd19bb8b343ba0f8 309 Gene3D G3DSA:3.30.1330.10 8 133 2.3E-13 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APE_0235.1 a270eab3a4e2d0c4dd19bb8b343ba0f8 309 SUPERFAMILY SSF55326 32 130 3.66E-14 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily APE_0791.1 266931a300b86a370a92f97833cf41ae 262 SUPERFAMILY SSF52540 5 189 4.74E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0791.1 266931a300b86a370a92f97833cf41ae 262 Pfam PF03029 Conserved hypothetical ATP binding protein 7 248 5.1E-59 T 23-10-2018 IPR004130 GPN-loop GTPase APE_0791.1 266931a300b86a370a92f97833cf41ae 262 Gene3D G3DSA:3.40.50.300 3 262 1.2E-49 T 23-10-2018 APE_2379b.1 07000e9bee33bfcf4060e3542f9e56ef 82 ProSitePatterns PS00961 Ribosomal protein S28e signature. 70 78 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2379b.1 07000e9bee33bfcf4060e3542f9e56ef 82 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 79 25.542 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2379b.1 07000e9bee33bfcf4060e3542f9e56ef 82 SUPERFAMILY SSF50249 14 81 3.43E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_2379b.1 07000e9bee33bfcf4060e3542f9e56ef 82 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 20 60 1.0E-14 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2379b.1 07000e9bee33bfcf4060e3542f9e56ef 82 Pfam PF01200 Ribosomal protein S28e 18 78 1.9E-31 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2379b.1 07000e9bee33bfcf4060e3542f9e56ef 82 Gene3D G3DSA:2.40.50.140 12 82 3.7E-32 T 23-10-2018 APE_2408.1 4a2c1f814f388d06dfbd28cd8d3a1378 237 SUPERFAMILY SSF52540 3 211 2.51E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2408.1 4a2c1f814f388d06dfbd28cd8d3a1378 237 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_2408.1 4a2c1f814f388d06dfbd28cd8d3a1378 237 Pfam PF00005 ABC transporter 23 156 2.0E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2408.1 4a2c1f814f388d06dfbd28cd8d3a1378 237 Gene3D G3DSA:3.40.50.300 2 218 3.2E-44 T 23-10-2018 APE_2408.1 4a2c1f814f388d06dfbd28cd8d3a1378 237 SMART SM00382 28 226 7.0E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0117.1 cfdfbb9135bb71dad32cc082902eaf2a 421 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 19 133 1.0E-62 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 APE_0117.1 cfdfbb9135bb71dad32cc082902eaf2a 421 Gene3D G3DSA:3.40.50.800 310 416 5.3E-19 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily APE_0117.1 cfdfbb9135bb71dad32cc082902eaf2a 421 SUPERFAMILY SSF52954 310 416 1.66E-16 T 23-10-2018 APE_0117.1 cfdfbb9135bb71dad32cc082902eaf2a 421 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 133 1.3E-42 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 APE_0117.1 cfdfbb9135bb71dad32cc082902eaf2a 421 Gene3D G3DSA:3.50.80.10 1 134 4.8E-47 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily APE_0117.1 cfdfbb9135bb71dad32cc082902eaf2a 421 Pfam PF03129 Anticodon binding domain 318 407 3.7E-16 T 23-10-2018 IPR004154 Anticodon-binding APE_1852.1 d8a2828bc96d1effc92d8175c358864d 407 Gene3D G3DSA:1.10.150.390 354 398 2.8E-18 T 23-10-2018 APE_1852.1 d8a2828bc96d1effc92d8175c358864d 407 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 405 38.158 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1852.1 d8a2828bc96d1effc92d8175c358864d 407 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 17 402 3.3E-164 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1852.1 d8a2828bc96d1effc92d8175c358864d 407 SUPERFAMILY SSF64484 29 399 4.35E-97 T 23-10-2018 APE_1852.1 d8a2828bc96d1effc92d8175c358864d 407 Pfam PF04998 RNA polymerase Rpb1, domain 5 25 347 9.4E-57 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 APE_1581.1 cff7b5d9e9bc9adb8839cf387a408c93 521 SUPERFAMILY SSF161098 312 503 8.9E-19 T 23-10-2018 IPR035906 MetI-like superfamily APE_1581.1 cff7b5d9e9bc9adb8839cf387a408c93 521 Gene3D G3DSA:1.10.3720.10 307 521 3.6E-13 T 23-10-2018 IPR035906 MetI-like superfamily APE_1581.1 cff7b5d9e9bc9adb8839cf387a408c93 521 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 336 520 1.2E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 Gene3D G3DSA:2.40.50.100 266 359 9.1E-18 T 23-10-2018 APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 Pfam PF00005 ABC transporter 20 161 8.3E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 Gene3D G3DSA:3.40.50.300 1 238 2.0E-76 T 23-10-2018 APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 SMART SM00382 28 211 2.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 SUPERFAMILY SSF50331 236 361 8.79E-18 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 SUPERFAMILY SSF52540 4 242 9.69E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2060.1 261bd326d177ea7b5b7ec62267f9d909 391 Gene3D G3DSA:2.40.50.140 284 347 9.1E-18 T 23-10-2018 APE_0442.1 9610f952de170e782d2a747f6e636820 118 SUPERFAMILY SSF57783 60 117 1.87E-22 T 23-10-2018 APE_0442.1 9610f952de170e782d2a747f6e636820 118 Pfam PF01096 Transcription factor S-II (TFIIS) 78 115 2.3E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 APE_0442.1 9610f952de170e782d2a747f6e636820 118 TIGRFAM TIGR01384 TFS_arch: transcription factor S 6 117 4.3E-31 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 APE_0442.1 9610f952de170e782d2a747f6e636820 118 Pfam PF02150 RNA polymerases M/15 Kd subunit 5 39 8.6E-10 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 APE_0442.1 9610f952de170e782d2a747f6e636820 118 Gene3D G3DSA:2.20.25.10 3 46 4.8E-8 T 23-10-2018 APE_0442.1 9610f952de170e782d2a747f6e636820 118 SMART SM00661 6 61 1.1E-11 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 APE_0442.1 9610f952de170e782d2a747f6e636820 118 SUPERFAMILY SSF57783 5 40 2.89E-7 T 23-10-2018 APE_0442.1 9610f952de170e782d2a747f6e636820 118 Gene3D G3DSA:2.20.25.10 69 118 7.7E-25 T 23-10-2018 APE_0442.1 9610f952de170e782d2a747f6e636820 118 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 79 114 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 APE_0442.1 9610f952de170e782d2a747f6e636820 118 PIRSF PIRSF005586 5 118 2.8E-40 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 APE_0442.1 9610f952de170e782d2a747f6e636820 118 SMART SM00440 77 116 1.5E-22 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 APE_1889 8f0513594d28f11c6f24d53ded930127 224 Pfam PF08241 Methyltransferase domain 51 136 6.9E-11 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APE_1889 8f0513594d28f11c6f24d53ded930127 224 SUPERFAMILY SSF53335 13 191 2.93E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1889 8f0513594d28f11c6f24d53ded930127 224 Gene3D G3DSA:3.40.50.150 9 221 2.3E-38 T 23-10-2018 APE_1285.1 2e71454e53fdc376d0c25a152b4adde2 333 PRINTS PR01270 Histone deacetylase superfamily signature 237 247 1.1E-5 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_1285.1 2e71454e53fdc376d0c25a152b4adde2 333 PRINTS PR01270 Histone deacetylase superfamily signature 153 168 1.1E-5 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_1285.1 2e71454e53fdc376d0c25a152b4adde2 333 Pfam PF00850 Histone deacetylase domain 14 270 6.4E-39 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_1285.1 2e71454e53fdc376d0c25a152b4adde2 333 Gene3D G3DSA:3.40.800.20 2 332 7.1E-51 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 APE_1285.1 2e71454e53fdc376d0c25a152b4adde2 333 SUPERFAMILY SSF52768 6 311 5.76E-53 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily APE_1085 602f916ded484a4ede680ec3e381c6d8 233 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 233 91.012 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 APE_1085 602f916ded484a4ede680ec3e381c6d8 233 SMART SM00654 10 210 1.9E-109 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 APE_1085 602f916ded484a4ede680ec3e381c6d8 233 SUPERFAMILY SSF55909 9 228 3.83E-66 T 23-10-2018 APE_1085 602f916ded484a4ede680ec3e381c6d8 233 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 13 229 1.5E-63 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 APE_1085 602f916ded484a4ede680ec3e381c6d8 233 Pfam PF01912 eIF-6 family 11 210 1.3E-67 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 APE_1085 602f916ded484a4ede680ec3e381c6d8 233 PIRSF PIRSF006413 8 231 1.9E-83 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 APE_1085 602f916ded484a4ede680ec3e381c6d8 233 Gene3D G3DSA:3.75.10.10 9 229 1.2E-77 T 23-10-2018 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 4 636 1.1E-226 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 SUPERFAMILY SSF55261 281 408 2.83E-39 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Gene3D G3DSA:1.10.10.410 574 632 5.0E-11 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 642 312.965 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 286 410 7.0E-54 T 23-10-2018 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Pfam PF02938 GAD domain 299 393 1.4E-21 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Gene3D G3DSA:1.10.150.380 457 553 2.5E-11 T 23-10-2018 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Pfam PF02637 GatB domain 507 632 4.5E-22 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Gene3D G3DSA:3.30.1360.30 275 408 1.3E-40 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 SUPERFAMILY SSF89095 501 632 1.36E-19 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 SUPERFAMILY SSF55931 3 457 5.04E-104 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 Pfam PF02934 GatB/GatE catalytic domain 12 449 3.4E-72 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 APE_2202 22fc7c4bdeaa181a3c89a9e9788ab720 642 SMART SM00845 488 632 6.7E-24 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 APE_1790.1 6817ea9d25518dad0e19b587342b76f0 215 SUPERFAMILY SSF56112 25 157 8.07E-11 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily APE_1183 7f3d0009b62f2e53c330e635e66830f0 309 Pfam PF08241 Methyltransferase domain 67 115 7.2E-15 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 APE_1183 7f3d0009b62f2e53c330e635e66830f0 309 SUPERFAMILY SSF53335 67 156 5.85E-18 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1183 7f3d0009b62f2e53c330e635e66830f0 309 Gene3D G3DSA:3.40.50.150 14 167 2.4E-18 T 23-10-2018 APE_2156.1 86d61712a9e57b3723ba009d2caba156 304 Pfam PF00753 Metallo-beta-lactamase superfamily 18 217 2.1E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2156.1 86d61712a9e57b3723ba009d2caba156 304 SMART SM00849 18 217 1.6E-34 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_2156.1 86d61712a9e57b3723ba009d2caba156 304 Gene3D G3DSA:3.60.15.10 2 264 2.9E-59 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_2156.1 86d61712a9e57b3723ba009d2caba156 304 SUPERFAMILY SSF56281 17 274 2.03E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_2093 d1f65f9f15cdbc2a78d00a04aa0b4de0 514 SUPERFAMILY SSF52540 172 512 7.71E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2093 d1f65f9f15cdbc2a78d00a04aa0b4de0 514 Pfam PF01935 Domain of unknown function DUF87 205 328 1.6E-14 T 23-10-2018 IPR002789 Helicase HerA, central domain APE_2093 d1f65f9f15cdbc2a78d00a04aa0b4de0 514 Gene3D G3DSA:3.40.50.300 365 514 1.1E-22 T 23-10-2018 APE_2093 d1f65f9f15cdbc2a78d00a04aa0b4de0 514 Gene3D G3DSA:3.40.50.300 188 291 6.8E-12 T 23-10-2018 APE_2042.1 6adb41982885962c3fa5f3ad4c15a342 232 Gene3D G3DSA:3.90.1490.10 132 212 4.3E-7 T 23-10-2018 APE_2042.1 6adb41982885962c3fa5f3ad4c15a342 232 Pfam PF01902 Diphthamide synthase 4 204 6.7E-22 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 APE_2042.1 6adb41982885962c3fa5f3ad4c15a342 232 SUPERFAMILY SSF52402 3 219 2.65E-50 T 23-10-2018 APE_2042.1 6adb41982885962c3fa5f3ad4c15a342 232 Gene3D G3DSA:3.40.50.620 3 128 3.6E-11 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 SUPERFAMILY SSF48140 1 143 3.66E-48 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 Pfam PF01280 Ribosomal protein L19e 3 145 1.8E-50 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 Gene3D G3DSA:1.10.1650.10 1 57 3.8E-20 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 2 150 26.17 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 ProSitePatterns PS00526 Ribosomal protein L19e signature. 6 25 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 Gene3D G3DSA:1.10.1200.240 61 153 1.9E-24 T 23-10-2018 APE_0348 aacc0015e0bcd07bf3e0c173f141f0e0 155 SMART SM01416 2 147 3.0E-74 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 Pfam PF01300 Telomere recombination 31 206 1.9E-59 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 SUPERFAMILY SSF55821 13 219 1.01E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 17 212 1.1E-68 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 Gene3D G3DSA:3.90.870.10 10 222 1.6E-85 T 23-10-2018 APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 PIRSF PIRSF004930 9 367 2.8E-128 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 Pfam PF03481 Putative GTP-binding controlling metal-binding 213 362 2.0E-22 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain APE_2397 a7feb771294fdfb7b826cf8ced2a33bc 367 Gene3D G3DSA:3.40.50.11030 225 367 2.9E-28 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 75 909 1.6E-211 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 Pfam PF02867 Ribonucleotide reductase, barrel domain 144 235 8.5E-32 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 Gene3D G3DSA:3.20.70.20 697 914 3.4E-45 T 23-10-2018 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 PRINTS PR01183 Ribonucleotide reductase large chain signature 494 517 3.7E-15 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 PRINTS PR01183 Ribonucleotide reductase large chain signature 532 554 3.7E-15 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 PRINTS PR01183 Ribonucleotide reductase large chain signature 219 238 3.7E-15 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 70 134 1.2E-13 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 SUPERFAMILY SSF48168 66 133 1.39E-10 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 SUPERFAMILY SSF51998 143 911 3.66E-124 T 23-10-2018 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 Gene3D G3DSA:3.20.70.20 64 236 2.9E-55 T 23-10-2018 APE_2062.1 46cbdc4546b991672a5dd3e05b0a5543 979 Pfam PF02867 Ribonucleotide reductase, barrel domain 297 899 2.6E-92 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 APE_0952.1 f3e8d680468662e86bca8264bfac2195 240 SUPERFAMILY SSF51366 21 232 9.68E-28 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_0952.1 f3e8d680468662e86bca8264bfac2195 240 Gene3D G3DSA:3.20.20.70 21 234 2.7E-48 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0952.1 f3e8d680468662e86bca8264bfac2195 240 SMART SM00934 21 228 1.8E-20 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_0952.1 f3e8d680468662e86bca8264bfac2195 240 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 22 227 2.6E-22 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_2347.1 64bdfb4d0dc791c79ba93a2d95a05699 92 Gene3D G3DSA:2.40.50.100 12 84 1.0E-16 T 23-10-2018 APE_2347.1 64bdfb4d0dc791c79ba93a2d95a05699 92 SUPERFAMILY SSF51230 19 90 2.09E-16 T 23-10-2018 IPR011053 Single hybrid motif APE_2347.1 64bdfb4d0dc791c79ba93a2d95a05699 92 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 32 61 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 APE_2347.1 64bdfb4d0dc791c79ba93a2d95a05699 92 Pfam PF00364 Biotin-requiring enzyme 22 79 2.7E-13 T 23-10-2018 IPR000089 Biotin/lipoyl attachment APE_2530.1 e3065b33077d6a1beb518ff1f9c83cd4 552 Pfam PF02538 Hydantoinase B/oxoprolinase 4 522 7.4E-186 T 23-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 APE_0550 727f96b4999cdcd0550ddc6c4367b4e6 326 Gene3D G3DSA:1.10.150.280 184 279 3.8E-28 T 23-10-2018 APE_0550 727f96b4999cdcd0550ddc6c4367b4e6 326 Gene3D G3DSA:2.40.50.140 26 89 1.7E-8 T 23-10-2018 APE_0550 727f96b4999cdcd0550ddc6c4367b4e6 326 SUPERFAMILY SSF160975 28 85 1.44E-14 T 23-10-2018 APE_0550 727f96b4999cdcd0550ddc6c4367b4e6 326 SUPERFAMILY SSF160975 175 289 4.84E-39 T 23-10-2018 APE_0550 727f96b4999cdcd0550ddc6c4367b4e6 326 Pfam PF04919 Protein of unknown function (DUF655) 25 290 5.6E-85 T 23-10-2018 IPR007003 Protein of unknown function DUF655 APE_0274a 836e2de0367f9b05a06bc253db69087a 71 Gene3D G3DSA:3.40.50.150 5 71 6.8E-11 T 23-10-2018 APE_0274a 836e2de0367f9b05a06bc253db69087a 71 SUPERFAMILY SSF53335 3 71 4.26E-11 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_0473.1 0dfdca6b8c8d8b12ffc81233b1293f5a 324 SMART SM00966 13 58 1.5E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0473.1 0dfdca6b8c8d8b12ffc81233b1293f5a 324 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 15 52 6.1E-10 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 APE_0473.1 0dfdca6b8c8d8b12ffc81233b1293f5a 324 SUPERFAMILY SSF89447 16 55 1.17E-8 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily APE_0178.1 12e6cbd1155962f86723a73fafb4570f 140 Gene3D G3DSA:3.40.50.300 2 123 7.6E-31 T 23-10-2018 APE_0178.1 12e6cbd1155962f86723a73fafb4570f 140 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 108 7.1E-30 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 APE_0178.1 12e6cbd1155962f86723a73fafb4570f 140 SUPERFAMILY SSF52540 2 106 4.77E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0178.1 12e6cbd1155962f86723a73fafb4570f 140 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 106 1.9E-26 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 APE_2604a.1 e2c170d6cab2f5e374d229fb75dcdbc3 140 Pfam PF00501 AMP-binding enzyme 83 140 3.8E-11 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 APE_2604a.1 e2c170d6cab2f5e374d229fb75dcdbc3 140 Gene3D G3DSA:3.40.50.12780 48 140 1.1E-15 T 23-10-2018 APE_2604a.1 e2c170d6cab2f5e374d229fb75dcdbc3 140 SUPERFAMILY SSF56801 7 139 1.57E-25 T 23-10-2018 APE_2604a.1 e2c170d6cab2f5e374d229fb75dcdbc3 140 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 22 73 1.3E-19 T 23-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 APE_0487 838b789a9dd136839e89ae900fcb690f 473 SUPERFAMILY SSF56176 3 216 1.92E-62 T 23-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 APE_0487 838b789a9dd136839e89ae900fcb690f 473 Pfam PF01565 FAD binding domain 39 178 7.4E-37 T 23-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 APE_0487 838b789a9dd136839e89ae900fcb690f 473 SUPERFAMILY SSF55103 219 471 2.78E-50 T 23-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 APE_0487 838b789a9dd136839e89ae900fcb690f 473 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 469 3.7E-69 T 23-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 APE_0487 838b789a9dd136839e89ae900fcb690f 473 Gene3D G3DSA:3.30.70.2740 344 425 2.5E-15 T 23-10-2018 APE_0487 838b789a9dd136839e89ae900fcb690f 473 Gene3D G3DSA:3.30.465.40 1 234 6.3E-65 T 23-10-2018 APE_0487 838b789a9dd136839e89ae900fcb690f 473 Gene3D G3DSA:1.10.45.10 426 470 1.9E-11 T 23-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 APE_0159 f033bec7bead1b1ff03de054b7fdf071 282 Pfam PF01040 UbiA prenyltransferase family 31 254 4.6E-36 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 APE_0159 f033bec7bead1b1ff03de054b7fdf071 282 Gene3D G3DSA:1.10.357.140 10 169 3.1E-16 T 23-10-2018 APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 SUPERFAMILY SSF52317 2 202 3.77E-47 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 PIRSF PIRSF005639 1 203 6.9E-63 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 Gene3D G3DSA:3.40.50.880 1 203 1.8E-64 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 200 35.388 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 198 5.8E-57 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_0244.1 ec3827348f829ccc9ba9565dc58147ef 203 Pfam PF01174 SNO glutamine amidotransferase family 5 201 5.1E-50 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 APE_2465.1 553da693c5adec0e64ea3138389a388f 451 Gene3D G3DSA:3.40.50.150 243 450 3.9E-59 T 23-10-2018 APE_2465.1 553da693c5adec0e64ea3138389a388f 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 234 248 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_2465.1 553da693c5adec0e64ea3138389a388f 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 432 449 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_2465.1 553da693c5adec0e64ea3138389a388f 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 263 273 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_2465.1 553da693c5adec0e64ea3138389a388f 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 332 344 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_2465.1 553da693c5adec0e64ea3138389a388f 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 382 398 1.5E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase APE_2465.1 553da693c5adec0e64ea3138389a388f 451 SUPERFAMILY SSF53335 168 450 3.49E-61 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_2465.1 553da693c5adec0e64ea3138389a388f 451 Pfam PF01189 16S rRNA methyltransferase RsmB/F 253 448 1.0E-49 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 APE_2465.1 553da693c5adec0e64ea3138389a388f 451 Gene3D G3DSA:3.30.70.1170 186 242 1.5E-24 T 23-10-2018 APE_2465.1 553da693c5adec0e64ea3138389a388f 451 Gene3D G3DSA:1.10.940.10 1 155 9.3E-49 T 23-10-2018 IPR035926 NusB-like superfamily APE_1136.1 80e662814e1143608c3c3464c95779f5 231 Gene3D G3DSA:3.30.200.20 24 96 9.3E-19 T 23-10-2018 APE_1136.1 80e662814e1143608c3c3464c95779f5 231 SUPERFAMILY SSF56112 11 205 1.05E-21 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily APE_1136.1 80e662814e1143608c3c3464c95779f5 231 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 19 220 1.7E-66 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 APE_1136.1 80e662814e1143608c3c3464c95779f5 231 Gene3D G3DSA:1.10.510.10 113 221 7.8E-24 T 23-10-2018 APE_1136.1 80e662814e1143608c3c3464c95779f5 231 Pfam PF01163 RIO1 family 53 154 1.7E-6 T 23-10-2018 APE_1303.1 8eab2102aaf853c2a944aa154065c055 427 SUPERFAMILY SSF53822 45 410 1.98E-48 T 23-10-2018 IPR028082 Periplasmic binding protein-like I APE_1303.1 8eab2102aaf853c2a944aa154065c055 427 Gene3D G3DSA:3.40.50.2300 164 398 1.2E-143 T 23-10-2018 APE_1303.1 8eab2102aaf853c2a944aa154065c055 427 Pfam PF13458 Periplasmic binding protein 45 399 4.7E-65 T 23-10-2018 IPR028081 Leucine-binding protein domain APE_1303.1 8eab2102aaf853c2a944aa154065c055 427 Gene3D G3DSA:3.40.50.2300 46 391 1.2E-143 T 23-10-2018 APE_0031.1 b7d50a20c1603ce2079741ba91a1d61a 484 Gene3D G3DSA:1.20.1250.20 267 471 1.3E-17 T 23-10-2018 APE_0031.1 b7d50a20c1603ce2079741ba91a1d61a 484 SUPERFAMILY SSF103473 15 466 1.06E-54 T 23-10-2018 IPR036259 MFS transporter superfamily APE_0031.1 b7d50a20c1603ce2079741ba91a1d61a 484 Gene3D G3DSA:1.20.1250.20 12 266 8.8E-38 T 23-10-2018 APE_0031.1 b7d50a20c1603ce2079741ba91a1d61a 484 Pfam PF07690 Major Facilitator Superfamily 18 417 9.0E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_0941 3e22d2db0f6974483acfde767aeff349 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 258 3.5E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0941 3e22d2db0f6974483acfde767aeff349 267 SUPERFAMILY SSF161098 9 255 2.22E-39 T 23-10-2018 IPR035906 MetI-like superfamily APE_0941 3e22d2db0f6974483acfde767aeff349 267 Gene3D G3DSA:1.10.3720.10 8 258 9.1E-35 T 23-10-2018 IPR035906 MetI-like superfamily APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 Pfam PF07676 WD40-like Beta Propeller Repeat 59 85 6.0E-6 T 23-10-2018 IPR011659 WD40-like Beta Propeller APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 SUPERFAMILY SSF53474 401 654 1.15E-57 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 SUPERFAMILY SSF82171 16 389 3.4E-36 T 23-10-2018 APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 Gene3D G3DSA:2.120.10.30 3 151 2.9E-16 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 Gene3D G3DSA:2.120.10.30 169 396 3.7E-10 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 Pfam PF00326 Prolyl oligopeptidase family 444 655 5.5E-55 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 APE_1832 5f8e197698b4c2b48ca9acc90a45d555 659 Gene3D G3DSA:3.40.50.1820 405 658 3.2E-64 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 Pfam PF08543 Phosphomethylpyrimidine kinase 19 263 1.2E-95 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 12 264 3.6E-100 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 SUPERFAMILY SSF53613 10 269 1.5E-80 T 23-10-2018 IPR029056 Ribokinase-like APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 Gene3D G3DSA:3.40.1190.20 3 271 4.8E-99 T 23-10-2018 IPR029056 Ribokinase-like APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 Pfam PF10120 Thiamine-phosphate synthase 280 450 2.5E-58 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 Gene3D G3DSA:3.40.225.10 272 457 2.2E-67 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APE_2400.1 bc0867b969bdf9cf29f3c7c58e7cecbc 460 SUPERFAMILY SSF53639 274 453 1.02E-60 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 11 97 1.0E-43 T 23-10-2018 APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 Pfam PF01918 Alba 8 70 2.0E-18 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 PIRSF PIRSF028732 3 98 5.0E-39 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 Gene3D G3DSA:3.30.110.20 1 102 1.1E-34 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 9 97 1.7E-30 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 SUPERFAMILY SSF82704 7 97 1.31E-21 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 APE_1823 c6736905ae47ebbe0ccf6d9703f42712 102 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 97 26.682 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 APE_2147.1 f3353f17779296f52bf6423cad3e58d5 458 Gene3D G3DSA:1.10.4100.10 21 434 4.6E-117 T 23-10-2018 APE_2147.1 f3353f17779296f52bf6423cad3e58d5 458 SUPERFAMILY SSF103378 4 445 4.05E-133 T 23-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 APE_2147.1 f3353f17779296f52bf6423cad3e58d5 458 Gene3D G3DSA:3.30.1330.120 265 402 4.6E-117 T 23-10-2018 APE_2147.1 f3353f17779296f52bf6423cad3e58d5 458 Pfam PF03972 MmgE/PrpD family 7 442 2.2E-140 T 23-10-2018 IPR005656 MmgE/PrpD GO:0016829 APE_1154.1 2856da2b3738ae80979d09f2d6e2e79f 214 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 1 195 35.541 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 APE_1154.1 2856da2b3738ae80979d09f2d6e2e79f 214 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 40 52 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1154.1 2856da2b3738ae80979d09f2d6e2e79f 214 SMART SM01397 1 195 1.7E-98 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1154.1 2856da2b3738ae80979d09f2d6e2e79f 214 Pfam PF01015 Ribosomal S3Ae family 6 195 3.5E-64 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 SUPERFAMILY SSF52402 6 144 2.93E-22 T 23-10-2018 APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 Gene3D G3DSA:3.40.50.620 3 146 2.3E-24 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 PRINTS PR01438 Universal stress protein signature 5 23 7.0E-6 T 23-10-2018 IPR006015 Universal stress protein A APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 PRINTS PR01438 Universal stress protein signature 106 118 7.0E-6 T 23-10-2018 IPR006015 Universal stress protein A APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 PRINTS PR01438 Universal stress protein signature 124 146 7.0E-6 T 23-10-2018 IPR006015 Universal stress protein A APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 Gene3D G3DSA:3.40.50.620 147 285 1.4E-15 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 SUPERFAMILY SSF52402 163 287 1.59E-16 T 23-10-2018 APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 Pfam PF00582 Universal stress protein family 163 287 6.5E-17 T 23-10-2018 IPR006016 UspA APE_0140.1 53973381f7dc4428b0a01b95a5abeacb 288 Pfam PF00582 Universal stress protein family 6 143 6.6E-19 T 23-10-2018 IPR006016 UspA APE_1877.1 fa4bccb42899b50addbeb5b33f947d5e 253 Gene3D G3DSA:1.20.1540.10 13 243 5.1E-26 T 23-10-2018 IPR035952 Rhomboid-like superfamily APE_1877.1 fa4bccb42899b50addbeb5b33f947d5e 253 Pfam PF01694 Rhomboid family 64 237 2.6E-38 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 APE_1877.1 fa4bccb42899b50addbeb5b33f947d5e 253 SUPERFAMILY SSF144091 15 239 1.01E-38 T 23-10-2018 APE_0412 bb7d43db6bc3eef36f58ed62cb3e05e9 362 Gene3D G3DSA:3.40.640.10 21 251 1.3E-48 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_0412 bb7d43db6bc3eef36f58ed62cb3e05e9 362 SUPERFAMILY SSF53383 21 315 1.21E-50 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_0412 bb7d43db6bc3eef36f58ed62cb3e05e9 362 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 85 222 2.6E-15 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 APE_0412 bb7d43db6bc3eef36f58ed62cb3e05e9 362 Gene3D G3DSA:3.90.1150.10 252 323 1.3E-48 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_1426 cc7536e7f6c7209bd5a400062859b17d 189 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 53 176 1.5E-31 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1426 cc7536e7f6c7209bd5a400062859b17d 189 Gene3D G3DSA:3.30.460.80 10 153 1.0E-29 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1426 cc7536e7f6c7209bd5a400062859b17d 189 SUPERFAMILY SSF143243 42 176 1.05E-34 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1426 cc7536e7f6c7209bd5a400062859b17d 189 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 117 153 1.0E-14 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 SUPERFAMILY SSF88697 83 169 1.16E-19 T 23-10-2018 IPR015947 PUA-like superfamily APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 51 164 1.6E-12 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 Gene3D G3DSA:3.10.450.120 9 173 2.4E-76 T 23-10-2018 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 Gene3D G3DSA:2.30.130.10 80 163 2.4E-76 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 Pfam PF09183 Domain of unknown function (DUF1947) 9 76 2.1E-8 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 SMART SM00359 84 163 3.5E-7 T 23-10-2018 IPR002478 PUA domain GO:0003723 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 7 169 7.6E-44 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 PIRSF PIRSF005067 2 174 1.8E-42 T 23-10-2018 IPR016437 MCT-1/Tma20 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 Pfam PF01472 PUA domain 84 151 7.7E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 APE_0525.1 04a3923230f544e18ac88cc5a977c472 178 SUPERFAMILY SSF88802 1 82 4.58E-50 T 23-10-2018 APE_1208.1 468c18c3e0555a89eed626cd10724242 363 SUPERFAMILY SSF53448 3 295 2.55E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1208.1 468c18c3e0555a89eed626cd10724242 363 Gene3D G3DSA:2.160.10.10 233 362 7.4E-17 T 23-10-2018 APE_1208.1 468c18c3e0555a89eed626cd10724242 363 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 274 307 1.2E-5 T 23-10-2018 IPR001451 Hexapeptide repeat APE_1208.1 468c18c3e0555a89eed626cd10724242 363 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 233 267 9.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat APE_1208.1 468c18c3e0555a89eed626cd10724242 363 Pfam PF12804 MobA-like NTP transferase domain 3 133 8.9E-11 T 23-10-2018 IPR025877 MobA-like NTP transferase APE_1208.1 468c18c3e0555a89eed626cd10724242 363 Gene3D G3DSA:3.90.550.10 1 232 1.7E-23 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1208.1 468c18c3e0555a89eed626cd10724242 363 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 259 287 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 ProSitePatterns PS00380 Rhodanese signature 1. 37 48 - T 23-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 SUPERFAMILY SSF52821 158 286 3.01E-41 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 SMART SM00450 154 281 3.6E-31 T 23-10-2018 IPR001763 Rhodanese-like domain APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 SMART SM00450 10 125 1.2E-19 T 23-10-2018 IPR001763 Rhodanese-like domain APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 Pfam PF00581 Rhodanese-like domain 160 276 1.7E-22 T 23-10-2018 IPR001763 Rhodanese-like domain APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 Pfam PF00581 Rhodanese-like domain 12 120 4.2E-17 T 23-10-2018 IPR001763 Rhodanese-like domain APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 Gene3D G3DSA:3.40.250.10 150 288 2.8E-47 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 ProSitePatterns PS00683 Rhodanese C-terminal signature. 265 275 - T 23-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 SUPERFAMILY SSF52821 7 132 4.45E-32 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily APE_2595.1 70c2b64fde77a6c35be778cd34d4f83d 289 Gene3D G3DSA:3.40.250.10 2 146 8.9E-37 T 23-10-2018 IPR036873 Rhodanese-like domain superfamily APE_0103.1 ffb62eb574eeae48a003a2492f39e2c0 155 Gene3D G3DSA:2.60.40.790 10 155 1.1E-9 T 23-10-2018 IPR008978 HSP20-like chaperone APE_0103.1 ffb62eb574eeae48a003a2492f39e2c0 155 Pfam PF00011 Hsp20/alpha crystallin family 69 152 1.5E-5 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain APE_0103.1 ffb62eb574eeae48a003a2492f39e2c0 155 SUPERFAMILY SSF49764 55 152 3.45E-12 T 23-10-2018 IPR008978 HSP20-like chaperone APE_2212.1 0d9b15dd7816208c1ad9e1316e1854e1 292 SUPERFAMILY SSF52096 62 245 1.31E-26 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APE_2212.1 0d9b15dd7816208c1ad9e1316e1854e1 292 Pfam PF01972 Serine dehydrogenase proteinase 6 281 7.8E-116 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 APE_2212.1 0d9b15dd7816208c1ad9e1316e1854e1 292 Gene3D G3DSA:3.90.226.10 61 265 1.4E-21 T 23-10-2018 APE_0543 015e912ffc2256bf16f9a022ea40fc7f 385 Gene3D G3DSA:1.20.1250.20 7 181 5.6E-11 T 23-10-2018 APE_0543 015e912ffc2256bf16f9a022ea40fc7f 385 Gene3D G3DSA:1.20.1250.20 195 372 1.0E-6 T 23-10-2018 APE_0543 015e912ffc2256bf16f9a022ea40fc7f 385 Pfam PF07690 Major Facilitator Superfamily 14 333 6.0E-11 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_0543 015e912ffc2256bf16f9a022ea40fc7f 385 SUPERFAMILY SSF103473 11 365 8.11E-21 T 23-10-2018 IPR036259 MFS transporter superfamily APE_0362a d80e585ac474276a2cc6d56f5e186a69 71 TIGRFAM TIGR00012 L29: ribosomal protein uL29 10 65 1.8E-19 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0362a d80e585ac474276a2cc6d56f5e186a69 71 Pfam PF00831 Ribosomal L29 protein 9 65 7.7E-21 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0362a d80e585ac474276a2cc6d56f5e186a69 71 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 6 65 16.372 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0362a d80e585ac474276a2cc6d56f5e186a69 71 Gene3D G3DSA:1.20.58.1890 1 69 2.8E-22 T 23-10-2018 APE_0362a d80e585ac474276a2cc6d56f5e186a69 71 SUPERFAMILY SSF46561 6 66 2.09E-18 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0362a d80e585ac474276a2cc6d56f5e186a69 71 ProSitePatterns PS00579 Ribosomal protein L29 signature. 44 58 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1396 99fec9d0380b94b802405c475c065985 387 SUPERFAMILY SSF161098 140 358 1.22E-26 T 23-10-2018 IPR035906 MetI-like superfamily APE_1396 99fec9d0380b94b802405c475c065985 387 Gene3D G3DSA:1.10.3720.10 134 378 1.4E-23 T 23-10-2018 IPR035906 MetI-like superfamily APE_1396 99fec9d0380b94b802405c475c065985 387 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 163 378 1.8E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1396 99fec9d0380b94b802405c475c065985 387 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 46 102 5.0E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain APE_0795.1 931c136bf15fafc4fa85d7e7a13eca7e 103 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 19 88 1.4E-10 T 23-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 Pfam PF04055 Radical SAM superfamily 55 213 2.3E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 SMART SM00729 48 252 5.7E-18 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 PIRSF PIRSF005963 1 293 9.5E-127 T 23-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 Hamap MF_00206 Lipoyl synthase [lipA]. 1 285 117.649 T 23-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 TIGRFAM TIGR00510 lipA: lipoyl synthase 15 282 9.8E-94 T 23-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 Gene3D G3DSA:3.20.20.70 49 288 4.7E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2344.1 640d7ad2803c204f7f01e8a77490c92b 293 SUPERFAMILY SSF102114 18 275 2.09E-54 T 23-10-2018 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 136 152 6.6E-12 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 160 173 6.6E-12 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 PRINTS PR01038 Arginyl-tRNA synthetase signature 121 136 6.6E-12 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 SUPERFAMILY SSF55190 11 104 4.58E-10 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 SMART SM00836 528 644 5.6E-27 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 11 644 8.3E-98 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 SUPERFAMILY SSF52374 118 520 3.44E-71 T 23-10-2018 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 Hamap MF_00123 Arginine--tRNA ligase [argS]. 9 644 25.775 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 Gene3D G3DSA:1.10.730.10 528 644 2.1E-27 T 23-10-2018 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 SMART SM01016 9 92 2.1E-4 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 SUPERFAMILY SSF47323 522 644 3.73E-28 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 Pfam PF05746 DALR anticodon binding domain 528 644 6.1E-28 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 Pfam PF00750 tRNA synthetases class I (R) 348 507 6.8E-20 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 Pfam PF00750 tRNA synthetases class I (R) 113 174 1.6E-10 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 APE_1756 68c3518a47ecfbba79a265fa06a8ae23 644 Gene3D G3DSA:3.30.1360.70 2 106 2.0E-8 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 APE_1231 e5141a7541923e35ff03ff07e03affad 282 Gene3D G3DSA:1.10.3210.30 13 198 6.7E-20 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 SUPERFAMILY SSF54791 10 86 2.28E-10 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 SUPERFAMILY SSF54791 92 183 1.9E-20 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 Pfam PF00013 KH domain 11 50 3.2E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 Pfam PF00013 KH domain 112 159 6.9E-5 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 SMART SM00322 90 163 0.041 T 23-10-2018 IPR004087 K Homology domain GO:0003676 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 SMART SM00322 6 76 0.012 T 23-10-2018 IPR004087 K Homology domain GO:0003676 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 11 185 1.4E-63 T 23-10-2018 IPR019964 KH domain protein, archaea APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 Gene3D G3DSA:3.30.1370.10 89 195 4.9E-42 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APE_0754.1 78c6a93b3ac7729740e653aec1a85461 195 Gene3D G3DSA:3.30.1370.10 5 88 1.3E-31 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 APE_1253 f39f6cc10945ff8ee05578b5e603be9b 306 Pfam PF00005 ABC transporter 30 175 9.1E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1253 f39f6cc10945ff8ee05578b5e603be9b 306 SUPERFAMILY SSF52540 12 234 7.29E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1253 f39f6cc10945ff8ee05578b5e603be9b 306 SMART SM00382 39 224 2.5E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1253 f39f6cc10945ff8ee05578b5e603be9b 306 Gene3D G3DSA:3.40.50.300 10 300 6.3E-69 T 23-10-2018 APE_1253 f39f6cc10945ff8ee05578b5e603be9b 306 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1319.1 bc7d2401d933d22be3662bdc38428202 415 Pfam PF01882 Protein of unknown function DUF58 194 276 8.3E-23 T 23-10-2018 IPR002881 Domain of unknown function DUF58 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 SUPERFAMILY SSF50193 14 140 1.28E-46 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 Gene3D G3DSA:2.40.150.20 2 140 7.4E-55 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 ProSitePatterns PS00049 Ribosomal protein L14 signature. 79 105 - T 23-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 19 140 20.441 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 SMART SM01374 19 140 2.2E-64 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 Pfam PF00238 Ribosomal protein L14p/L23e 20 140 1.4E-38 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 APE_0359 9ec0f8c6d3f7f74c9e3436dd3b0f40cb 140 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 13 140 5.6E-65 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal APE_2520.1 ecaf48bc5d9a67d7796187a4052443c4 237 SUPERFAMILY SSF51395 57 142 4.27E-5 T 23-10-2018 APE_2520.1 ecaf48bc5d9a67d7796187a4052443c4 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 215 5.6E-13 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 APE_2520.1 ecaf48bc5d9a67d7796187a4052443c4 237 Gene3D G3DSA:3.40.50.12500 6 236 1.4E-87 T 23-10-2018 APE_2520.1 ecaf48bc5d9a67d7796187a4052443c4 237 PIRSF PIRSF015736 1 237 2.9E-90 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase APE_0343 c4b891717b6529d2afd4e9ea6fcbd421 158 Gene3D G3DSA:4.10.990.10 5 55 5.1E-6 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal APE_0343 c4b891717b6529d2afd4e9ea6fcbd421 158 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 2 148 13.768 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 APE_0343 c4b891717b6529d2afd4e9ea6fcbd421 158 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 31 146 4.3E-17 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P APE_0343 c4b891717b6529d2afd4e9ea6fcbd421 158 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0343 c4b891717b6529d2afd4e9ea6fcbd421 158 SUPERFAMILY SSF52080 6 154 1.83E-30 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily APE_0343 c4b891717b6529d2afd4e9ea6fcbd421 158 Gene3D G3DSA:3.100.10.10 64 154 1.9E-19 T 23-10-2018 APE_2577.1 b6d4f590cf819d6674e3c48a45045845 291 Pfam PF04055 Radical SAM superfamily 45 211 6.5E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_2577.1 b6d4f590cf819d6674e3c48a45045845 291 SUPERFAMILY SSF102114 44 239 1.96E-10 T 23-10-2018 APE_1848.1 24eddbb30bde8f0f481d6b5559bbbbe8 156 SUPERFAMILY SSF103256 31 155 6.93E-19 T 23-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 APE_1848.1 24eddbb30bde8f0f481d6b5559bbbbe8 156 Pfam PF02577 Bifunctional nuclease 50 151 1.4E-8 T 23-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 APE_1848.1 24eddbb30bde8f0f481d6b5559bbbbe8 156 Gene3D G3DSA:3.10.690.10 30 156 4.0E-7 T 23-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 APE_2247 50243bac89410a4c3d35d801d26a6049 194 Gene3D G3DSA:3.10.300.10 114 191 1.3E-11 T 23-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APE_2247 50243bac89410a4c3d35d801d26a6049 194 Gene3D G3DSA:3.10.300.10 2 110 6.3E-25 T 23-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APE_2247 50243bac89410a4c3d35d801d26a6049 194 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 8 180 3.5E-41 T 23-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APE_2247 50243bac89410a4c3d35d801d26a6049 194 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 7 183 28.422 T 23-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 APE_2247 50243bac89410a4c3d35d801d26a6049 194 SUPERFAMILY SSF50486 4 188 5.57E-46 T 23-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 APE_0148.1 0e5c8b1669d915a7ba2e0edaa021ace8 144 Pfam PF01951 Archease protein family (MTH1598/TM1083) 8 144 7.9E-41 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 APE_0148.1 0e5c8b1669d915a7ba2e0edaa021ace8 144 Hamap MF_01222 Protein archease. 4 144 44.275 T 23-10-2018 IPR022952 Archease, archaea APE_0148.1 0e5c8b1669d915a7ba2e0edaa021ace8 144 Gene3D G3DSA:3.55.10.10 5 144 4.9E-41 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 APE_0148.1 0e5c8b1669d915a7ba2e0edaa021ace8 144 SUPERFAMILY SSF69819 5 144 1.03E-43 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 APE_0148.1 0e5c8b1669d915a7ba2e0edaa021ace8 144 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 10 143 9.0E-74 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 APE_0237.1 e30af1088c57b517ce6adafd7867df2d 211 Pfam PF06778 Chlorite dismutase 24 210 5.8E-35 T 23-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase APE_0237.1 e30af1088c57b517ce6adafd7867df2d 211 Gene3D G3DSA:3.30.70.1100 99 211 1.0E-16 T 23-10-2018 APE_0237.1 e30af1088c57b517ce6adafd7867df2d 211 SUPERFAMILY SSF54909 3 210 1.34E-39 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 Pfam PF09377 SBDS protein C-terminal domain 100 185 8.2E-18 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 SUPERFAMILY SSF109728 81 153 3.4E-23 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 SUPERFAMILY SSF54980 156 228 1.22E-16 T 23-10-2018 IPR035647 EF-G domain III/V-like APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 Gene3D G3DSA:3.30.70.240 163 233 5.6E-21 T 23-10-2018 APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 SUPERFAMILY SSF89895 4 86 1.7E-23 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 Gene3D G3DSA:1.10.10.900 87 161 2.1E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 10 93 3.6E-23 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 Gene3D G3DSA:3.30.1250.10 7 86 1.0E-27 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 6 229 6.7E-68 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 APE_1167.1 8ee16ec04541b7e5fe44bab49bd41704 233 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 36 55 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site APE_1865.1 46dbb86edb6c3a88121793d43250a097 366 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 16 355 2.2E-101 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme APE_1865.1 46dbb86edb6c3a88121793d43250a097 366 Gene3D G3DSA:3.20.20.70 70 301 2.1E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1865.1 46dbb86edb6c3a88121793d43250a097 366 Pfam PF04055 Radical SAM superfamily 92 253 4.3E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1865.1 46dbb86edb6c3a88121793d43250a097 366 PIRSF PIRSF004869 2 328 1.1E-94 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted APE_1865.1 46dbb86edb6c3a88121793d43250a097 366 SUPERFAMILY SSF102114 61 331 4.19E-38 T 23-10-2018 APE_1865.1 46dbb86edb6c3a88121793d43250a097 366 SMART SM00729 86 293 0.0039 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_1092.1 326665a134b9df8405f06699440a62c5 163 Gene3D G3DSA:2.20.25.200 63 113 1.5E-19 T 23-10-2018 APE_1092.1 326665a134b9df8405f06699440a62c5 163 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 37 100 1.3E-12 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 APE_1092.1 326665a134b9df8405f06699440a62c5 163 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 8 109 22.287 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 APE_1758.1 1185d37e7f27e6a0d6694156ece10757 481 Gene3D G3DSA:3.90.1860.10 1 481 1.8E-202 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 APE_1758.1 1185d37e7f27e6a0d6694156ece10757 481 Pfam PF01139 tRNA-splicing ligase RtcB 46 481 2.1E-166 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 APE_1758.1 1185d37e7f27e6a0d6694156ece10757 481 SUPERFAMILY SSF103365 3 481 3.79E-175 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 APE_2485.1 fb0a55c12b31d328c09b1faccb09464b 184 Pfam PF01944 Stage II sporulation protein M 22 174 3.1E-22 T 23-10-2018 IPR002798 Stage II sporulation protein M-like APE_0086 45c3799d374daf66c58c453c985373b6 163 PIRSF PIRSF000239 1 159 2.1E-28 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_0086 45c3799d374daf66c58c453c985373b6 163 Gene3D G3DSA:3.40.30.10 3 150 4.5E-45 T 23-10-2018 APE_0086 45c3799d374daf66c58c453c985373b6 163 Pfam PF00578 AhpC/TSA family 4 128 4.7E-39 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_0086 45c3799d374daf66c58c453c985373b6 163 SUPERFAMILY SSF52833 3 150 1.72E-49 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1725 7932550062e486e258a39a27aae0d34f 571 SUPERFAMILY SSF81648 219 376 6.67E-15 T 23-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APE_1725 7932550062e486e258a39a27aae0d34f 571 Gene3D G3DSA:1.20.810.10 25 403 7.1E-62 T 23-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 APE_1725 7932550062e486e258a39a27aae0d34f 571 SUPERFAMILY SSF81342 11 260 1.11E-37 T 23-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 APE_1725 7932550062e486e258a39a27aae0d34f 571 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 93 263 2.8E-30 T 23-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 SUPERFAMILY SSF52743 117 769 2.49E-54 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 665 675 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 Pfam PF00082 Subtilase family 195 718 5.4E-31 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 200 211 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 PRINTS PR00723 Subtilisin serine protease family (S8) signature 456 469 5.3E-14 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 PRINTS PR00723 Subtilisin serine protease family (S8) signature 664 680 5.3E-14 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 214 5.3E-14 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 Gene3D G3DSA:3.40.50.200 428 731 8.7E-47 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_0607 98c4d35485d24a4c1afa7735f9e3a689 1331 Gene3D G3DSA:3.40.50.200 176 255 7.1E-9 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 PIRSF PIRSF002131 3 132 7.2E-36 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 Gene3D G3DSA:3.30.420.80 2 133 6.6E-64 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 9 125 5.3E-65 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 Pfam PF00411 Ribosomal protein S11 11 129 7.8E-48 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 SUPERFAMILY SSF53137 6 131 4.71E-38 T 23-10-2018 APE_1742.1 49ad42a59eb4504a68f292c2782b2878 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 6 130 22.999 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 APE_0812 026c8af8f76103bdfa08bdfc0543df0e 327 Gene3D G3DSA:1.10.1670.10 182 320 2.7E-6 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 APE_0812 026c8af8f76103bdfa08bdfc0543df0e 327 SUPERFAMILY SSF48150 9 286 8.25E-24 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 APE_1771 85430b999db10e255a7678872ec5fbcc 281 SUPERFAMILY SSF53213 76 240 7.32E-5 T 23-10-2018 APE_1771 85430b999db10e255a7678872ec5fbcc 281 Hamap MF_00055 MEMO1 family protein . 2 280 59.013 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 APE_1771 85430b999db10e255a7678872ec5fbcc 281 Pfam PF01875 Memo-like protein 6 278 9.0E-69 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 APE_1771 85430b999db10e255a7678872ec5fbcc 281 Gene3D G3DSA:3.40.830.10 1 281 9.4E-58 T 23-10-2018 APE_1771 85430b999db10e255a7678872ec5fbcc 281 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 4 279 1.4E-84 T 23-10-2018 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 Gene3D G3DSA:3.40.50.10260 12 227 2.0E-52 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 Gene3D G3DSA:3.40.1190.20 231 498 9.4E-64 T 23-10-2018 IPR029056 Ribokinase-like APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 PIRSF PIRSF017184 14 496 1.7E-89 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 16 223 2.9E-43 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 SUPERFAMILY SSF53613 234 492 4.18E-52 T 23-10-2018 IPR029056 Ribokinase-like APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 Pfam PF03853 YjeF-related protein N-terminus 37 202 6.7E-38 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 236 494 1.1E-49 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 Pfam PF01256 Carbohydrate kinase 254 490 6.1E-41 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 SUPERFAMILY SSF64153 16 252 2.09E-54 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 430 440 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 16 223 22.509 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 APE_2362.1 637c899bdd9fa41960168011b241a1a8 499 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 231 499 20.893 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 APE_0153.1 26dfd0ef89600b0e9d530fb3f2f73702 248 Gene3D G3DSA:1.10.10.10 4 76 1.5E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0153.1 26dfd0ef89600b0e9d530fb3f2f73702 248 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 13 76 1.1E-11 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal APE_0157 d1a06dd5419266698f8f8fcee613fde3 246 Gene3D G3DSA:3.40.50.10420 37 212 2.1E-11 T 23-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily APE_0157 d1a06dd5419266698f8f8fcee613fde3 246 SUPERFAMILY SSF100950 6 221 4.05E-32 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_0157 d1a06dd5419266698f8f8fcee613fde3 246 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 205 3.7E-44 T 23-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase APE_1963.1 bbf21b94a69eaebadc96f2308b81c0aa 390 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 263 283 - T 23-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 APE_1963.1 bbf21b94a69eaebadc96f2308b81c0aa 390 Gene3D G3DSA:3.40.50.1970 2 187 6.7E-39 T 23-10-2018 APE_1963.1 bbf21b94a69eaebadc96f2308b81c0aa 390 Gene3D G3DSA:1.20.1090.10 189 390 4.2E-59 T 23-10-2018 APE_1963.1 bbf21b94a69eaebadc96f2308b81c0aa 390 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 382 3.5E-100 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 APE_1963.1 bbf21b94a69eaebadc96f2308b81c0aa 390 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 176 204 - T 23-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 APE_1963.1 bbf21b94a69eaebadc96f2308b81c0aa 390 SUPERFAMILY SSF56796 3 389 2.88E-98 T 23-10-2018 APE_1702 286da19e9ee8dc0a09d2d57ad6526497 253 SUPERFAMILY SSF52540 3 236 7.99E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1702 286da19e9ee8dc0a09d2d57ad6526497 253 Gene3D G3DSA:3.40.50.300 3 249 6.7E-56 T 23-10-2018 APE_1702 286da19e9ee8dc0a09d2d57ad6526497 253 Pfam PF00005 ABC transporter 18 174 1.4E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1702 286da19e9ee8dc0a09d2d57ad6526497 253 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 3 244 1.1E-82 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 APE_1702 286da19e9ee8dc0a09d2d57ad6526497 253 SMART SM00382 27 224 7.5E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 Gene3D G3DSA:3.40.50.1220 176 308 5.7E-51 T 23-10-2018 APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 Pfam PF01012 Electron transfer flavoprotein domain 56 164 2.5E-13 T 23-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 SUPERFAMILY SSF52402 15 213 2.37E-16 T 23-10-2018 APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 Gene3D G3DSA:3.40.50.620 16 174 7.0E-15 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 182 265 2.2E-30 T 23-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 SUPERFAMILY SSF52467 181 302 2.62E-43 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily APE_0135 b23f530024e0cfd0a6102fbbcba336ea 308 PIRSF PIRSF000089 16 307 6.1E-87 T 23-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 APE_0722 cdcd27d69482074186bc849b512dc9d0 219 SUPERFAMILY SSF46785 8 91 8.19E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1102 823d3ae3e38a6359989fb8fb5c15d5af 139 Gene3D G3DSA:3.40.50.1010 7 138 3.5E-27 T 23-10-2018 APE_1102 823d3ae3e38a6359989fb8fb5c15d5af 139 Pfam PF17146 PIN domain of ribonuclease 16 103 4.6E-18 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 APE_1102 823d3ae3e38a6359989fb8fb5c15d5af 139 SUPERFAMILY SSF88723 16 131 4.32E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_1102 823d3ae3e38a6359989fb8fb5c15d5af 139 SMART SM00670 14 121 2.2E-12 T 23-10-2018 IPR002716 PIN domain APE_1102 823d3ae3e38a6359989fb8fb5c15d5af 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 16 130 10.767 T 23-10-2018 IPR022907 VapC family GO:0004540 APE_0176.1 1b741cfea6eed7377e36693973b19720 219 Gene3D G3DSA:3.60.15.10 2 217 1.9E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0176.1 1b741cfea6eed7377e36693973b19720 219 Pfam PF13483 Beta-lactamase superfamily domain 5 167 1.2E-34 T 23-10-2018 APE_0176.1 1b741cfea6eed7377e36693973b19720 219 SUPERFAMILY SSF56281 4 192 4.9E-25 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 Pfam PF02754 Cysteine-rich domain 558 648 6.4E-13 T 23-10-2018 IPR004017 Cysteine-rich domain APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 Pfam PF02754 Cysteine-rich domain 419 504 5.4E-11 T 23-10-2018 IPR004017 Cysteine-rich domain APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 SUPERFAMILY SSF103501 14 228 1.57E-20 T 23-10-2018 IPR036197 NarG-like superfamily APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 SUPERFAMILY SSF46548 253 362 2.79E-18 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 Gene3D G3DSA:1.20.950.20 47 223 7.1E-7 T 23-10-2018 APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 Pfam PF13183 4Fe-4S dicluster domain 267 346 3.7E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 334 345 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0101.1 2b89220e17f9b4fdde32f6a1a4305004 672 Gene3D G3DSA:1.10.1060.10 234 368 4.8E-9 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_0129.1 38f279204c4bae14e8b74680ff264ba9 371 Pfam PF01882 Protein of unknown function DUF58 210 295 4.4E-18 T 23-10-2018 IPR002881 Domain of unknown function DUF58 APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 1.5E-136 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 Pfam PF06745 KaiC 5 237 5.1E-88 T 23-10-2018 IPR014774 KaiC-like domain APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 PRINTS PR01874 DNA repair protein radA signature 14 42 1.1E-8 T 23-10-2018 APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 PRINTS PR01874 DNA repair protein radA signature 167 195 1.1E-8 T 23-10-2018 APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 PRINTS PR01874 DNA repair protein radA signature 56 73 1.1E-8 T 23-10-2018 APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 Gene3D G3DSA:3.40.50.300 1 247 6.2E-72 T 23-10-2018 APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 SUPERFAMILY SSF52540 3 236 2.71E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1505.1 cd49012aa809e17edb8fd8d2ad5f3d1b 248 Hamap MF_01076 UPF0273 protein . 2 245 58.511 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like APE_0605.1 6d444e5ac5c27abf67ffc628b152dc67 195 Gene3D G3DSA:3.40.50.410 10 185 2.3E-22 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_0605.1 6d444e5ac5c27abf67ffc628b152dc67 195 SUPERFAMILY SSF53300 9 176 1.07E-20 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_0605.1 6d444e5ac5c27abf67ffc628b152dc67 195 Pfam PF13519 von Willebrand factor type A domain 13 120 5.8E-9 T 23-10-2018 IPR002035 von Willebrand factor, type A APE_2066.1 3ffd68c77867fd4200bc1f81ec3e96fa 385 SUPERFAMILY SSF53756 14 378 1.0E-93 T 23-10-2018 APE_2066.1 3ffd68c77867fd4200bc1f81ec3e96fa 385 Pfam PF00534 Glycosyl transferases group 1 193 358 1.1E-43 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 APE_2066.1 3ffd68c77867fd4200bc1f81ec3e96fa 385 Gene3D G3DSA:3.40.50.2000 199 364 7.9E-47 T 23-10-2018 APE_2066.1 3ffd68c77867fd4200bc1f81ec3e96fa 385 Pfam PF13439 Glycosyltransferase Family 4 26 192 1.9E-24 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APE_2066.1 3ffd68c77867fd4200bc1f81ec3e96fa 385 Gene3D G3DSA:3.40.50.2000 14 198 5.5E-36 T 23-10-2018 APE_2015.1 5d23abeaeeaf3654030999aaa1b5ae21 121 Pfam PF16992 DNA-directed RNA polymerase, subunit G 6 110 1.0E-23 T 23-10-2018 IPR031555 DNA-directed RNA polymerase, subunit G APE_2015.1 5d23abeaeeaf3654030999aaa1b5ae21 121 Gene3D G3DSA:2.40.50.140 2 112 6.3E-30 T 23-10-2018 APE_1443.1 aaa75583f890519b0caf0fc539cf8551 180 Gene3D G3DSA:3.40.50.10480 1 169 2.9E-69 T 23-10-2018 APE_1443.1 aaa75583f890519b0caf0fc539cf8551 180 SUPERFAMILY SSF52954 1 167 2.75E-34 T 23-10-2018 APE_1443.1 aaa75583f890519b0caf0fc539cf8551 180 SMART SM00879 1 170 1.8E-10 T 23-10-2018 IPR007109 Brix domain APE_1443.1 aaa75583f890519b0caf0fc539cf8551 180 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 1 173 28.445 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein APE_2502.1 d574704d15a0192410f858ff1276f20a 321 Pfam PF04909 Amidohydrolase 109 310 1.3E-27 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APE_2502.1 d574704d15a0192410f858ff1276f20a 321 SUPERFAMILY SSF51556 9 311 1.3E-31 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_2502.1 d574704d15a0192410f858ff1276f20a 321 Gene3D G3DSA:3.20.20.140 9 313 5.2E-36 T 23-10-2018 APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 Pfam PF00005 ABC transporter 273 419 2.5E-15 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 SUPERFAMILY SSF52540 273 472 1.65E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 Gene3D G3DSA:3.40.50.300 259 482 2.0E-32 T 23-10-2018 APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 Gene3D G3DSA:3.40.50.300 3 238 1.1E-50 T 23-10-2018 APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 SUPERFAMILY SSF52540 5 226 1.15E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 SMART SM00382 30 217 1.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0063 f71ac51bf86ae88ae2ce31a690fecf81 492 Pfam PF00005 ABC transporter 21 168 1.3E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1652 a0e67e112029de42e115a389513fc1bb 389 SUPERFAMILY SSF102114 35 354 1.96E-67 T 23-10-2018 APE_1652 a0e67e112029de42e115a389513fc1bb 389 Pfam PF04055 Radical SAM superfamily 40 185 5.4E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_1652 a0e67e112029de42e115a389513fc1bb 389 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 284 373 1.2E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain APE_1652 a0e67e112029de42e115a389513fc1bb 389 SMART SM00729 35 233 1.1E-8 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_1652 a0e67e112029de42e115a389513fc1bb 389 PIRSF PIRSF037420 21 386 2.5E-93 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E APE_1652 a0e67e112029de42e115a389513fc1bb 389 Pfam PF13353 4Fe-4S single cluster domain 39 123 1.7E-5 T 23-10-2018 APE_1652 a0e67e112029de42e115a389513fc1bb 389 Gene3D G3DSA:3.20.20.70 35 324 3.7E-53 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1652 a0e67e112029de42e115a389513fc1bb 389 Pfam PF13186 Iron-sulfur cluster-binding domain 284 346 1.6E-5 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain APE_1436.1 77546fb54f466d8d747c758ac7001954 248 SMART SM00891 14 94 2.8E-27 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 Gene3D G3DSA:1.10.150.20 150 223 1.8E-26 T 23-10-2018 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 Gene3D G3DSA:3.40.50.10130 7 142 1.9E-48 T 23-10-2018 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 Pfam PF14520 Helix-hairpin-helix domain 168 216 3.8E-11 T 23-10-2018 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 SUPERFAMILY SSF47781 158 218 2.64E-15 T 23-10-2018 IPR010994 RuvA domain 2-like APE_1436.1 77546fb54f466d8d747c758ac7001954 248 SMART SM00278 166 185 1.1 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 SMART SM00278 198 217 1.4 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 Pfam PF02732 ERCC4 domain 17 136 7.0E-22 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 APE_1436.1 77546fb54f466d8d747c758ac7001954 248 SUPERFAMILY SSF52980 11 139 1.34E-34 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 APE_1437.1 ffa78f5429b15ed0ff504a196b6fa867 348 Pfam PF01368 DHH family 24 167 4.6E-13 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 APE_1437.1 ffa78f5429b15ed0ff504a196b6fa867 348 Pfam PF02272 DHHA1 domain 249 315 4.9E-8 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 APE_1437.1 ffa78f5429b15ed0ff504a196b6fa867 348 SUPERFAMILY SSF64182 21 315 2.22E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily APE_1437.1 ffa78f5429b15ed0ff504a196b6fa867 348 Gene3D G3DSA:3.90.1640.10 8 205 4.0E-34 T 23-10-2018 APE_1768.1 df9c3efc07bd746788a9303d380a270c 249 SUPERFAMILY SSF53633 13 246 1.05E-28 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1768.1 df9c3efc07bd746788a9303d380a270c 249 Pfam PF00696 Amino acid kinase family 14 228 4.4E-26 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 APE_1768.1 df9c3efc07bd746788a9303d380a270c 249 Gene3D G3DSA:3.40.1160.10 12 248 5.1E-41 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily APE_1768.1 df9c3efc07bd746788a9303d380a270c 249 PIRSF PIRSF016496 8 249 6.4E-57 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 APE_2050.1 d0e92c3f4ac22ffffa98525ed6ace709 336 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 76 286 2.9E-20 T 23-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 APE_2050.1 d0e92c3f4ac22ffffa98525ed6ace709 336 Gene3D G3DSA:3.20.20.210 1 326 2.9E-53 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APE_2050.1 d0e92c3f4ac22ffffa98525ed6ace709 336 SUPERFAMILY SSF51726 7 325 3.79E-53 T 23-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 APE_2011.1 fc43d0708ddeb491ead5d2331a7e804f 171 Gene3D G3DSA:1.10.260.40 75 171 6.2E-18 T 23-10-2018 APE_2011.1 fc43d0708ddeb491ead5d2331a7e804f 171 SUPERFAMILY SSF47413 80 145 2.15E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APE_2011.1 fc43d0708ddeb491ead5d2331a7e804f 171 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 7 168 6.4E-32 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 APE_2011.1 fc43d0708ddeb491ead5d2331a7e804f 171 Pfam PF01381 Helix-turn-helix 87 139 5.9E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_2011.1 fc43d0708ddeb491ead5d2331a7e804f 171 SMART SM00530 86 141 2.7E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_0962 b5030e2c177f11573cea3c534a08a25b 271 Gene3D G3DSA:1.10.10.10 215 264 9.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0962 b5030e2c177f11573cea3c534a08a25b 271 SUPERFAMILY SSF46785 215 262 5.68E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2480a f9a715bec9fbea6b5b4735c9d9f3052c 68 Pfam PF07754 Domain of unknown function (DUF1610) 19 42 1.2E-7 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 APE_1980.1 89aed3a6b8b7a93fc1a9fb50c48dcc41 268 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 5 255 44.688 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea APE_1980.1 89aed3a6b8b7a93fc1a9fb50c48dcc41 268 Pfam PF00994 Probable molybdopterin binding domain 9 173 5.4E-37 T 23-10-2018 IPR001453 MoaB/Mog domain APE_1980.1 89aed3a6b8b7a93fc1a9fb50c48dcc41 268 Gene3D G3DSA:3.40.980.10 5 173 1.5E-54 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_1980.1 89aed3a6b8b7a93fc1a9fb50c48dcc41 268 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 170 6.5E-25 T 23-10-2018 IPR001453 MoaB/Mog domain APE_1980.1 89aed3a6b8b7a93fc1a9fb50c48dcc41 268 SUPERFAMILY SSF53218 4 203 4.19E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily APE_1980.1 89aed3a6b8b7a93fc1a9fb50c48dcc41 268 SMART SM00852 8 174 1.9E-41 T 23-10-2018 IPR001453 MoaB/Mog domain APE_0761.1 3e43a6c475465c68f3c6751728487dad 91 Gene3D G3DSA:3.30.460.10 1 80 3.9E-15 T 23-10-2018 APE_0761.1 3e43a6c475465c68f3c6751728487dad 91 Pfam PF01909 Nucleotidyltransferase domain 3 61 2.7E-10 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 APE_0761.1 3e43a6c475465c68f3c6751728487dad 91 SUPERFAMILY SSF81301 2 68 1.06E-15 T 23-10-2018 APE_0293 eae1564cf4c41c0f455881e73f311626 101 SUPERFAMILY SSF46785 24 85 5.77E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0293 eae1564cf4c41c0f455881e73f311626 101 Gene3D G3DSA:1.10.10.10 21 96 1.3E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0293 eae1564cf4c41c0f455881e73f311626 101 SMART SM00418 20 91 0.0043 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_0293 eae1564cf4c41c0f455881e73f311626 101 Pfam PF01022 Bacterial regulatory protein, arsR family 24 66 5.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 APE_1044 41cb1bdd328df2669576b1cfa5db1fd6 249 SUPERFAMILY SSF55469 13 248 7.85E-60 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APE_1044 41cb1bdd328df2669576b1cfa5db1fd6 249 Pfam PF00881 Nitroreductase family 19 171 1.7E-21 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 APE_1044 41cb1bdd328df2669576b1cfa5db1fd6 249 PIRSF PIRSF005426 10 249 6.4E-76 T 23-10-2018 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 APE_1044 41cb1bdd328df2669576b1cfa5db1fd6 249 Gene3D G3DSA:3.40.109.10 12 249 2.5E-60 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 APE_0993.1 a46fb2a03f5fce60a043d98ea04d6e4d 244 Pfam PF01048 Phosphorylase superfamily 17 214 8.5E-36 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 APE_0993.1 a46fb2a03f5fce60a043d98ea04d6e4d 244 Gene3D G3DSA:3.40.50.1580 3 241 1.9E-55 T 23-10-2018 APE_0993.1 a46fb2a03f5fce60a043d98ea04d6e4d 244 SUPERFAMILY SSF53167 5 217 5.37E-56 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APE_2170 195035da9380f956d95a850e7dcbe17c 111 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 7 110 3.9E-35 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 APE_2170 195035da9380f956d95a850e7dcbe17c 111 Gene3D G3DSA:1.10.10.1410 7 63 1.5E-14 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2170 195035da9380f956d95a850e7dcbe17c 111 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 6 107 12.801 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2170 195035da9380f956d95a850e7dcbe17c 111 Pfam PF00428 60s Acidic ribosomal protein 22 109 2.3E-15 T 23-10-2018 APE_0545.1 fb4d539d7a7d335a2f23e9dee063dad8 214 Gene3D G3DSA:3.40.50.2020 7 211 2.1E-50 T 23-10-2018 APE_0545.1 fb4d539d7a7d335a2f23e9dee063dad8 214 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 5 211 37.083 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 APE_0545.1 fb4d539d7a7d335a2f23e9dee063dad8 214 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 11 212 9.0E-75 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 APE_0545.1 fb4d539d7a7d335a2f23e9dee063dad8 214 SUPERFAMILY SSF53271 11 211 4.28E-45 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_0545.1 fb4d539d7a7d335a2f23e9dee063dad8 214 Pfam PF14681 Uracil phosphoribosyltransferase 11 209 1.7E-41 T 23-10-2018 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 Gene3D G3DSA:1.10.10.10 3 57 1.4E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.2E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.2E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.2E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 SMART SM00344 6 110 5.0E-27 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 Gene3D G3DSA:3.30.70.920 60 141 5.4E-19 T 23-10-2018 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 SUPERFAMILY SSF46785 4 56 2.07E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 Pfam PF01037 Lrp/AsnC ligand binding domain 69 140 2.1E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 2.1E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_1458a a09520d6ee00be85c6228ed11e42b71b 141 SUPERFAMILY SSF54909 65 140 5.36E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel APE_1418.1 e294912f93ad34093697192559503ca9 160 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 21 155 1.4E-15 T 23-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1418.1 e294912f93ad34093697192559503ca9 160 Gene3D G3DSA:1.20.120.1200 7 159 1.8E-10 T 23-10-2018 APE_0053.1 9fddec053a2cf8e84740b411f1b5355c 286 SUPERFAMILY SSF56529 71 280 8.37E-58 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 APE_0053.1 9fddec053a2cf8e84740b411f1b5355c 286 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 279 1.0E-57 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 APE_0053.1 9fddec053a2cf8e84740b411f1b5355c 286 Gene3D G3DSA:3.90.850.10 74 285 1.4E-64 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 Gene3D G3DSA:4.10.80.40 545 579 4.4E-8 T 23-10-2018 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 Pfam PF02910 Fumarate reductase flavoprotein C-term 457 583 1.5E-40 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 SUPERFAMILY SSF51905 3 425 1.03E-69 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 10 583 1.8E-224 T 23-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 SUPERFAMILY SSF56425 233 357 6.73E-38 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 Gene3D G3DSA:3.50.50.60 10 413 6.1E-140 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 Gene3D G3DSA:3.90.700.10 243 362 6.1E-140 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 PIRSF PIRSF000171 2 577 7.3E-50 T 23-10-2018 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 Pfam PF00890 FAD binding domain 10 401 6.1E-108 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 Gene3D G3DSA:1.20.58.100 428 544 1.4E-31 T 23-10-2018 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 SUPERFAMILY SSF46977 448 583 3.4E-49 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0950.1 4f03f5d35af8f51be1c2e76ff8b436d7 583 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 47 56 - T 23-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_1861.1 bb6a1256f6c11c2ae3e1ce1e9bd0ddbd 250 Gene3D G3DSA:3.60.21.10 24 137 3.5E-7 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_1861.1 bb6a1256f6c11c2ae3e1ce1e9bd0ddbd 250 SUPERFAMILY SSF56300 26 191 1.32E-15 T 23-10-2018 APE_1861.1 bb6a1256f6c11c2ae3e1ce1e9bd0ddbd 250 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 25 221 3.4E-36 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like APE_1861.1 bb6a1256f6c11c2ae3e1ce1e9bd0ddbd 250 PIRSF PIRSF000887 4 250 1.0E-67 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 APE_1861.1 bb6a1256f6c11c2ae3e1ce1e9bd0ddbd 250 Pfam PF00149 Calcineurin-like phosphoesterase 26 125 1.2E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APE_0433a 6267942d483f101d5fe2459f7f5769d0 58 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 54 17.89 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 APE_0433a 6267942d483f101d5fe2459f7f5769d0 58 SUPERFAMILY SSF144210 3 57 1.07E-18 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 APE_0433a 6267942d483f101d5fe2459f7f5769d0 58 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 52 6.6E-22 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 APE_0433a 6267942d483f101d5fe2459f7f5769d0 58 Gene3D G3DSA:2.20.28.40 1 56 1.3E-21 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 APE_0097.1 f26b9e890d9801d81cd8076fb97878f9 214 Pfam PF04250 Protein of unknown function (DUF429) 16 145 4.0E-7 T 23-10-2018 IPR007362 Protein of unknown function DUF429 APE_0097.1 f26b9e890d9801d81cd8076fb97878f9 214 PIRSF PIRSF024051 13 214 5.8E-65 T 23-10-2018 IPR018036 Protein of unknown function DUF429, subgroup APE_0390 1d9586f8e255276218dafe3c6f5fa317 159 Gene3D G3DSA:3.40.630.30 2 158 4.1E-25 T 23-10-2018 APE_0390 1d9586f8e255276218dafe3c6f5fa317 159 SUPERFAMILY SSF55729 8 150 8.44E-25 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_0390 1d9586f8e255276218dafe3c6f5fa317 159 Pfam PF00583 Acetyltransferase (GNAT) family 60 148 2.2E-16 T 23-10-2018 IPR000182 GNAT domain APE_0656.1 8ebb1a7206b620d81170c888aad37170 456 Gene3D G3DSA:3.90.600.20 159 252 1.0E-25 T 23-10-2018 APE_0656.1 8ebb1a7206b620d81170c888aad37170 456 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 1 432 31.878 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 APE_0656.1 8ebb1a7206b620d81170c888aad37170 456 Gene3D G3DSA:3.30.70.2200 1 154 8.1E-35 T 23-10-2018 APE_0656.1 8ebb1a7206b620d81170c888aad37170 456 Gene3D G3DSA:2.40.50.1010 253 405 1.2E-38 T 23-10-2018 APE_0656.1 8ebb1a7206b620d81170c888aad37170 456 Pfam PF08489 Domain of unknown function (DUF1743) 141 253 2.5E-31 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 APE_1629 02368ebee5d66abf981b268367e82c02 101 Gene3D G3DSA:3.30.780.10 22 100 2.5E-29 T 23-10-2018 APE_1629 02368ebee5d66abf981b268367e82c02 101 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 3 98 4.4E-37 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 APE_1629 02368ebee5d66abf981b268367e82c02 101 SUPERFAMILY SSF55159 22 97 3.01E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 APE_1629 02368ebee5d66abf981b268367e82c02 101 PIRSF PIRSF037511 3 99 2.9E-27 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 APE_1629 02368ebee5d66abf981b268367e82c02 101 Hamap MF_00604 Protein translation factor SUI1 homolog. 6 95 27.015 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea APE_1629 02368ebee5d66abf981b268367e82c02 101 Pfam PF01253 Translation initiation factor SUI1 22 93 1.1E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 APE_1547.1 f279668867c78007c31f4c1f9f44a874 578 SUPERFAMILY SSF50993 5 316 3.66E-136 T 23-10-2018 APE_1547.1 f279668867c78007c31f4c1f9f44a874 578 Gene3D G3DSA:3.40.50.1820 318 578 1.6E-78 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_1547.1 f279668867c78007c31f4c1f9f44a874 578 Gene3D G3DSA:2.130.10.150 18 317 5.4E-147 T 23-10-2018 APE_1547.1 f279668867c78007c31f4c1f9f44a874 578 Pfam PF00326 Prolyl oligopeptidase family 379 562 1.7E-40 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 APE_1547.1 f279668867c78007c31f4c1f9f44a874 578 SUPERFAMILY SSF53474 331 564 6.05E-52 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_0340.1 c5b1d70348ac2060a1478c33f8e78d2e 739 Pfam PF14871 Hypothetical glycosyl hydrolase 6 30 168 1.4E-44 T 23-10-2018 IPR028212 Hypothetical glycosyl hydrolase 6 APE_0340.1 c5b1d70348ac2060a1478c33f8e78d2e 739 Gene3D G3DSA:3.40.50.880 374 612 2.0E-18 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_0340.1 c5b1d70348ac2060a1478c33f8e78d2e 739 SUPERFAMILY SSF52317 420 612 1.18E-5 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like APE_1706 7c436c89590b4422f0b1a062469bde45 391 Pfam PF01458 Uncharacterized protein family (UPF0051) 149 369 8.8E-35 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 APE_1706 7c436c89590b4422f0b1a062469bde45 391 SUPERFAMILY SSF101960 7 381 6.54E-53 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily APE_0426.1 6ba69958c8aed45a9705c15c46701888 361 Gene3D G3DSA:3.90.550.10 2 239 3.5E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0426.1 6ba69958c8aed45a9705c15c46701888 361 Pfam PF04138 GtrA-like protein 242 360 2.3E-20 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 APE_0426.1 6ba69958c8aed45a9705c15c46701888 361 Pfam PF00535 Glycosyl transferase family 2 12 146 3.1E-30 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APE_0426.1 6ba69958c8aed45a9705c15c46701888 361 SUPERFAMILY SSF53448 8 182 6.1E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1921 70bf318dc23ab4c7c9cd484eb789f3cd 167 Gene3D G3DSA:3.10.28.10 2 162 5.8E-32 T 23-10-2018 IPR027434 Homing endonuclease APE_1921 70bf318dc23ab4c7c9cd484eb789f3cd 167 Pfam PF00961 LAGLIDADG endonuclease 11 100 3.7E-8 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 APE_1921 70bf318dc23ab4c7c9cd484eb789f3cd 167 SUPERFAMILY SSF55608 8 117 2.83E-18 T 23-10-2018 IPR027434 Homing endonuclease APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 PIRSF PIRSF000778 2 94 3.6E-33 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 Gene3D G3DSA:3.90.940.10 12 93 9.2E-25 T 23-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 Pfam PF01192 RNA polymerase Rpb6 18 70 3.3E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 SUPERFAMILY SSF63562 5 90 1.44E-25 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 20 77 21.43 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 23 37 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0914 fe109fa95ba9e6b1c6bcaf5d7d9658f0 103 SMART SM01409 16 71 0.0021 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0768.1 b2ab881e6ae500ef7d2474e3fcb24e83 333 SUPERFAMILY SSF53697 37 319 4.23E-26 T 23-10-2018 APE_0768.1 b2ab881e6ae500ef7d2474e3fcb24e83 333 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 175 325 4.3E-32 T 23-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 APE_0768.1 b2ab881e6ae500ef7d2474e3fcb24e83 333 Gene3D G3DSA:3.40.50.10490 188 326 3.2E-26 T 23-10-2018 APE_0768.1 b2ab881e6ae500ef7d2474e3fcb24e83 333 Gene3D G3DSA:3.40.50.10490 5 161 1.7E-20 T 23-10-2018 APE_0768.1 b2ab881e6ae500ef7d2474e3fcb24e83 333 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 8 325 1.7E-111 T 23-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 APE_0020.1 081685c1c33009e05962a68c02d8e93f 464 SUPERFAMILY SSF53383 2 392 3.99E-96 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_0020.1 081685c1c33009e05962a68c02d8e93f 464 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 45 315 5.1E-28 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 APE_0020.1 081685c1c33009e05962a68c02d8e93f 464 Gene3D G3DSA:3.90.1150.10 3 384 9.0E-97 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_0020.1 081685c1c33009e05962a68c02d8e93f 464 Gene3D G3DSA:3.40.640.10 36 292 9.0E-97 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_0481.1 2431ae3a72a1b0ebdba52b040d4365c4 98 Gene3D G3DSA:3.30.70.20 1 30 7.4E-6 T 23-10-2018 APE_0481.1 2431ae3a72a1b0ebdba52b040d4365c4 98 Gene3D G3DSA:1.10.1060.10 54 96 2.3E-6 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_0481.1 2431ae3a72a1b0ebdba52b040d4365c4 98 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 15 26 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0481.1 2431ae3a72a1b0ebdba52b040d4365c4 98 Pfam PF13183 4Fe-4S dicluster domain 12 79 3.4E-12 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_0481.1 2431ae3a72a1b0ebdba52b040d4365c4 98 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 65 76 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0481.1 2431ae3a72a1b0ebdba52b040d4365c4 98 SUPERFAMILY SSF46548 10 93 7.85E-20 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 APE_1462a 5ed7e730fc968675b46431c3efa66845 56 SUPERFAMILY SSF57783 2 34 2.55E-5 T 23-10-2018 APE_1462a 5ed7e730fc968675b46431c3efa66845 56 Gene3D G3DSA:2.20.28.160 1 56 5.9E-23 T 23-10-2018 APE_0007.1 4a87ce025fe333a8522be1d74523160e 511 SUPERFAMILY SSF82171 65 347 2.75E-6 T 23-10-2018 APE_1668 21f1c2d2a29d2950ccb8904bcebdc27d 106 SUPERFAMILY SSF54913 3 104 5.93E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta APE_1668 21f1c2d2a29d2950ccb8904bcebdc27d 106 Gene3D G3DSA:3.30.70.120 1 105 6.4E-36 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal APE_1668 21f1c2d2a29d2950ccb8904bcebdc27d 106 Pfam PF03091 CutA1 divalent ion tolerance protein 6 101 7.2E-34 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 APE_0528 5b1804de98aba2ac4f4a23c78fac4a3c 377 SUPERFAMILY SSF141130 18 365 1.24E-88 T 23-10-2018 APE_0528 5b1804de98aba2ac4f4a23c78fac4a3c 377 Pfam PF03069 Acetamidase/Formamidase family 11 365 2.6E-122 T 23-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 APE_0528 5b1804de98aba2ac4f4a23c78fac4a3c 377 Gene3D G3DSA:2.60.120.580 4 120 2.1E-24 T 23-10-2018 APE_0528 5b1804de98aba2ac4f4a23c78fac4a3c 377 Gene3D G3DSA:2.60.120.580 176 263 5.1E-25 T 23-10-2018 APE_0528 5b1804de98aba2ac4f4a23c78fac4a3c 377 Gene3D G3DSA:3.10.28.20 295 366 4.5E-6 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 Gene3D G3DSA:1.10.3860.10 2 422 5.6E-155 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 APE_2583.1 25f74591931a19e761a6757160f853f3 424 SUPERFAMILY SSF118215 15 412 3.01E-124 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 359 379 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 231 250 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 77 102 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 7 27 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 297 323 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 332 351 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 PRINTS PR00173 Glutamate-aspartate symporter signature 48 68 5.8E-52 T 23-10-2018 APE_2583.1 25f74591931a19e761a6757160f853f3 424 Pfam PF00375 Sodium:dicarboxylate symporter family 14 410 5.7E-129 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 APE_2583.1 25f74591931a19e761a6757160f853f3 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 40 55 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site APE_2154a 9786db091dcc3016741df08fee824cf1 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 4 24 9.5E-8 T 23-10-2018 APE_2154a 9786db091dcc3016741df08fee824cf1 59 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 24 43 9.5E-8 T 23-10-2018 APE_2154a 9786db091dcc3016741df08fee824cf1 59 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 8 52 2.2E-18 T 23-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 APE_2154a 9786db091dcc3016741df08fee824cf1 59 Pfam PF02416 mttA/Hcf106 family 7 55 1.9E-18 T 23-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 APE_0924.1 a51cd7f5678bea0b9f49f37743939b07 387 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 290 4.1E-33 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_0303 a0ebd1ac341f0569a2440e4204a699e6 342 SUPERFAMILY SSF161098 93 328 6.05E-13 T 23-10-2018 IPR035906 MetI-like superfamily APE_0303 a0ebd1ac341f0569a2440e4204a699e6 342 Gene3D G3DSA:1.10.3720.10 89 335 1.4E-17 T 23-10-2018 IPR035906 MetI-like superfamily APE_0303 a0ebd1ac341f0569a2440e4204a699e6 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 341 1.4E-36 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1660.1 94c521091233e72712b31affef7fcca1 148 SMART SM00881 12 113 2.2E-27 T 23-10-2018 IPR003781 CoA-binding GO:0048037 APE_1660.1 94c521091233e72712b31affef7fcca1 148 SUPERFAMILY SSF51735 8 142 1.87E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1660.1 94c521091233e72712b31affef7fcca1 148 Gene3D G3DSA:3.40.50.720 6 147 1.2E-40 T 23-10-2018 APE_1660.1 94c521091233e72712b31affef7fcca1 148 Pfam PF13380 CoA binding domain 16 139 2.1E-35 T 23-10-2018 IPR003781 CoA-binding GO:0048037 APE_0883a 56f54ce079f1a02fbe598dd601058ccf 76 Pfam PF01402 Ribbon-helix-helix protein, copG family 19 53 3.3E-6 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 APE_1661 7392bb31db52d367c3e538d9de78995b 124 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 6 124 8.7E-39 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 APE_1661 7392bb31db52d367c3e538d9de78995b 124 SUPERFAMILY SSF102462 5 124 8.55E-40 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 APE_1661 7392bb31db52d367c3e538d9de78995b 124 Gene3D G3DSA:3.40.1490.10 6 124 6.2E-40 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 APE_1661 7392bb31db52d367c3e538d9de78995b 124 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 7 124 3.7E-37 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 APE_1661 7392bb31db52d367c3e538d9de78995b 124 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 6 124 28.622 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 12 262 1.1E-70 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 262 9.3E-30 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 SUPERFAMILY SSF51735 11 158 2.89E-28 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 10 264 23.361 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 Gene3D G3DSA:1.10.3730.10 163 266 6.2E-30 T 23-10-2018 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 11 100 2.2E-17 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 Gene3D G3DSA:3.40.50.720 4 162 4.1E-40 T 23-10-2018 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 SUPERFAMILY SSF48179 159 266 1.65E-28 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APE_0146.1 6261d2b1dd9ff620d12bbe3c9d4aea9a 279 PIRSF PIRSF000193 10 267 1.1E-61 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 APE_1683.1 b003fb156b8cd5dbb0af333f417e2531 322 SUPERFAMILY SSF52540 4 295 2.89E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1683.1 b003fb156b8cd5dbb0af333f417e2531 322 Pfam PF03308 ArgK protein 19 286 4.3E-117 T 23-10-2018 APE_1683.1 b003fb156b8cd5dbb0af333f417e2531 322 Gene3D G3DSA:3.40.50.300 41 252 8.3E-79 T 23-10-2018 APE_1683.1 b003fb156b8cd5dbb0af333f417e2531 322 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 14 311 1.3E-137 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 APE_1779.1 4f255904a52b7cca3fc3f3fc34ab9ce0 145 SUPERFAMILY SSF88697 1 122 3.98E-17 T 23-10-2018 IPR015947 PUA-like superfamily APE_2125.1 7f3e9c9fc7ae661f4b21b856ad785f4f 161 Pfam PF00578 AhpC/TSA family 5 132 1.1E-37 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_2125.1 7f3e9c9fc7ae661f4b21b856ad785f4f 161 SUPERFAMILY SSF52833 2 154 1.82E-46 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_2125.1 7f3e9c9fc7ae661f4b21b856ad785f4f 161 PIRSF PIRSF000239 1 156 1.2E-24 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_2125.1 7f3e9c9fc7ae661f4b21b856ad785f4f 161 Gene3D G3DSA:3.40.30.10 1 161 4.4E-54 T 23-10-2018 APE_2409 724588349f775366483eb0bec6c9c3b1 169 SUPERFAMILY SSF52540 4 129 1.94E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0255.1 8081f3b330e6746495e7263225b6f3be 250 Gene3D G3DSA:3.90.550.10 1 243 6.4E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0255.1 8081f3b330e6746495e7263225b6f3be 250 SUPERFAMILY SSF53448 4 239 1.17E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0255.1 8081f3b330e6746495e7263225b6f3be 250 Pfam PF00483 Nucleotidyl transferase 7 237 4.6E-28 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APE_0288 b90c057f00bc8eb1ef97344066814a75 196 Pfam PF12802 MarR family 32 92 1.2E-13 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APE_0288 b90c057f00bc8eb1ef97344066814a75 196 SMART SM00347 27 127 1.1E-13 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 APE_0288 b90c057f00bc8eb1ef97344066814a75 196 SUPERFAMILY SSF46785 4 140 4.2E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0288 b90c057f00bc8eb1ef97344066814a75 196 Gene3D G3DSA:1.10.10.10 2 142 4.5E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0288 b90c057f00bc8eb1ef97344066814a75 196 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 23-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site APE_1181 c2aaae42a1315a9c4266d9d8a4536d65 355 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 3 355 2.7E-156 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form APE_1181 c2aaae42a1315a9c4266d9d8a4536d65 355 Gene3D G3DSA:2.160.10.10 241 352 3.4E-6 T 23-10-2018 APE_1181 c2aaae42a1315a9c4266d9d8a4536d65 355 Gene3D G3DSA:3.90.550.10 1 240 5.1E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1181 c2aaae42a1315a9c4266d9d8a4536d65 355 SUPERFAMILY SSF53448 1 309 2.48E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1181 c2aaae42a1315a9c4266d9d8a4536d65 355 Pfam PF00483 Nucleotidyl transferase 3 236 2.7E-41 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APE_1872.1 ef8e73a467eb154adad690ad5195c31e 377 SUPERFAMILY SSF53901 4 218 5.76E-22 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1872.1 ef8e73a467eb154adad690ad5195c31e 377 SUPERFAMILY SSF53901 239 356 6.58E-17 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1872.1 ef8e73a467eb154adad690ad5195c31e 377 Pfam PF00108 Thiolase, N-terminal domain 17 179 5.5E-10 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 APE_1872.1 ef8e73a467eb154adad690ad5195c31e 377 Gene3D G3DSA:3.40.47.10 3 376 8.9E-72 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 APE_1872.1 ef8e73a467eb154adad690ad5195c31e 377 PIRSF PIRSF000429 3 373 8.4E-30 T 23-10-2018 IPR002155 Thiolase GO:0016747 APE_0988 f1fd4d683ec3a63c9fa4b938434c75a3 155 SUPERFAMILY SSF52121 4 130 1.7E-21 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_0988 f1fd4d683ec3a63c9fa4b938434c75a3 155 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 23 128 2.3E-8 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_0988 f1fd4d683ec3a63c9fa4b938434c75a3 155 Gene3D G3DSA:3.40.50.960 1 155 2.1E-52 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_0988 f1fd4d683ec3a63c9fa4b938434c75a3 155 PIRSF PIRSF015750 1 155 8.6E-73 T 23-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_0988 f1fd4d683ec3a63c9fa4b938434c75a3 155 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 4 154 2.4E-80 T 23-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 APE_2361.1 75790702643586ee8bc450b57f960893 279 Gene3D G3DSA:3.40.50.1820 9 271 5.9E-44 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2361.1 75790702643586ee8bc450b57f960893 279 SUPERFAMILY SSF53474 11 270 3.63E-43 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2361.1 75790702643586ee8bc450b57f960893 279 Pfam PF12697 Alpha/beta hydrolase family 32 264 9.6E-25 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 APE_0198.1 76df48e75ba59c6a27b62cafe716a0bd 117 Gene3D G3DSA:1.10.8.10 75 113 2.7E-20 T 23-10-2018 APE_0198.1 76df48e75ba59c6a27b62cafe716a0bd 117 SMART SM01407 6 66 6.3E-12 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain APE_0198.1 76df48e75ba59c6a27b62cafe716a0bd 117 SUPERFAMILY SSF46934 75 114 1.13E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 APE_0198.1 76df48e75ba59c6a27b62cafe716a0bd 117 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 114 19.773 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 APE_1411.1 38fcd3eb0bc87d46c8b6b3960eadf391 701 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 78 130 8.2E-15 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1411.1 38fcd3eb0bc87d46c8b6b3960eadf391 701 Pfam PF00361 Proton-conducting membrane transporter 192 483 4.0E-48 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1411.1 38fcd3eb0bc87d46c8b6b3960eadf391 701 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 91 116 4.9E-34 T 23-10-2018 APE_1411.1 38fcd3eb0bc87d46c8b6b3960eadf391 701 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 255 276 4.9E-34 T 23-10-2018 APE_1411.1 38fcd3eb0bc87d46c8b6b3960eadf391 701 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 277 303 4.9E-34 T 23-10-2018 APE_1411.1 38fcd3eb0bc87d46c8b6b3960eadf391 701 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 476 495 4.9E-34 T 23-10-2018 APE_0166.1 5430fef22c18ccabc699e86e70d3054e 180 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 10 120 2.0E-59 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APE_0166.1 5430fef22c18ccabc699e86e70d3054e 180 Pfam PF01923 Cobalamin adenosyltransferase 5 168 6.2E-42 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APE_0166.1 5430fef22c18ccabc699e86e70d3054e 180 SUPERFAMILY SSF89028 4 175 4.32E-41 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APE_0166.1 5430fef22c18ccabc699e86e70d3054e 180 Gene3D G3DSA:1.20.1200.10 23 180 7.2E-38 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APE_0166.1 5430fef22c18ccabc699e86e70d3054e 180 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 5 179 3.0E-35 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 APE_2610 f974de791127da798ce9876bbdd84103 1165 Gene3D G3DSA:3.40.50.740 53 194 5.2E-17 T 23-10-2018 APE_2610 f974de791127da798ce9876bbdd84103 1165 Pfam PF00384 Molybdopterin oxidoreductase 331 733 6.3E-13 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_2610 f974de791127da798ce9876bbdd84103 1165 Pfam PF01568 Molydopterin dinucleotide binding domain 981 1040 8.9E-15 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 APE_2610 f974de791127da798ce9876bbdd84103 1165 SMART SM00926 49 141 2.5E-13 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_2610 f974de791127da798ce9876bbdd84103 1165 SUPERFAMILY SSF50692 954 1046 2.49E-22 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily APE_2610 f974de791127da798ce9876bbdd84103 1165 SUPERFAMILY SSF53706 48 962 3.54E-107 T 23-10-2018 APE_2610 f974de791127da798ce9876bbdd84103 1165 Gene3D G3DSA:3.40.50.740 619 808 5.2E-13 T 23-10-2018 APE_2610 f974de791127da798ce9876bbdd84103 1165 Gene3D G3DSA:2.40.40.20 926 1088 6.2E-21 T 23-10-2018 APE_0035.1 dbd13319427ae73455d1fd7982b3a7c0 468 Gene3D G3DSA:3.40.190.10 86 461 2.3E-57 T 23-10-2018 APE_0035.1 dbd13319427ae73455d1fd7982b3a7c0 468 Gene3D G3DSA:1.20.5.1070 25 73 3.4E-5 T 23-10-2018 APE_0035.1 dbd13319427ae73455d1fd7982b3a7c0 468 SUPERFAMILY SSF53850 88 461 8.69E-61 T 23-10-2018 APE_0035.1 dbd13319427ae73455d1fd7982b3a7c0 468 Pfam PF01547 Bacterial extracellular solute-binding protein 102 382 2.7E-32 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein APE_1611 eb8935fbe1303084712452a5ed187ac2 650 Pfam PF05670 Domain of unknown function (DUF814) 423 522 4.9E-25 T 23-10-2018 IPR008532 Domain of unknown function DUF814 APE_1611 eb8935fbe1303084712452a5ed187ac2 650 Gene3D G3DSA:2.30.310.10 5 155 7.1E-20 T 23-10-2018 APE_1611 eb8935fbe1303084712452a5ed187ac2 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 9 396 7.1E-34 T 23-10-2018 APE_0976.1 cfc4706e6083bd4da3c06f14d630021e 100 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 2 81 30.021 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 APE_0976.1 cfc4706e6083bd4da3c06f14d630021e 100 SUPERFAMILY SSF50104 3 89 3.31E-24 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily APE_0976.1 cfc4706e6083bd4da3c06f14d630021e 100 Gene3D G3DSA:2.30.30.30 3 88 5.6E-37 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 APE_0537.1 cda8bda91130bc72fc89c0b0da3eb195 338 Gene3D G3DSA:3.40.50.620 4 317 1.4E-62 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0537.1 cda8bda91130bc72fc89c0b0da3eb195 338 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 205 311 7.5E-23 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 APE_0537.1 cda8bda91130bc72fc89c0b0da3eb195 338 Pfam PF01171 PP-loop family 54 193 1.2E-8 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 APE_0537.1 cda8bda91130bc72fc89c0b0da3eb195 338 PIRSF PIRSF004976 2 321 1.4E-93 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 APE_0537.1 cda8bda91130bc72fc89c0b0da3eb195 338 SUPERFAMILY SSF52402 28 237 4.89E-38 T 23-10-2018 APE_0279a.1 b2ff0e6c890cc97571c822ea5e34e5c1 66 Gene3D G3DSA:4.10.1150.10 1 61 2.1E-11 T 23-10-2018 IPR024069 AF2212-like domain superfamily APE_0279a.1 b2ff0e6c890cc97571c822ea5e34e5c1 66 Pfam PF01954 Protein of unknown function DUF104 1 58 2.6E-20 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_0279a.1 b2ff0e6c890cc97571c822ea5e34e5c1 66 SUPERFAMILY SSF141694 1 57 3.66E-14 T 23-10-2018 APE_0644.1 d41191524f20c3a613396401c8eed320 327 Pfam PF13394 4Fe-4S single cluster domain 17 106 1.0E-4 T 23-10-2018 APE_0644.1 d41191524f20c3a613396401c8eed320 327 Pfam PF04055 Radical SAM superfamily 18 125 1.3E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_0644.1 d41191524f20c3a613396401c8eed320 327 SUPERFAMILY SSF102114 13 184 2.22E-19 T 23-10-2018 APE_0644.1 d41191524f20c3a613396401c8eed320 327 Gene3D G3DSA:3.20.20.70 11 125 1.7E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0311 3d63bb44afb46015821942ddd09c8594 276 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 3 209 2.5E-34 T 23-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 APE_0311 3d63bb44afb46015821942ddd09c8594 276 PIRSF PIRSF015582 1 275 1.7E-77 T 23-10-2018 IPR011206 Citrate lyase beta subunit-like APE_0311 3d63bb44afb46015821942ddd09c8594 276 SUPERFAMILY SSF51621 2 221 2.13E-52 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APE_0311 3d63bb44afb46015821942ddd09c8594 276 Gene3D G3DSA:3.20.20.60 1 273 2.7E-81 T 23-10-2018 APE_1495.1 094c6bc21a5f7bd79860311a3ff053ae 326 Pfam PF00248 Aldo/keto reductase family 12 305 6.7E-40 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain APE_1495.1 094c6bc21a5f7bd79860311a3ff053ae 326 SUPERFAMILY SSF51430 5 307 2.75E-53 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APE_1495.1 094c6bc21a5f7bd79860311a3ff053ae 326 Gene3D G3DSA:3.20.20.100 3 315 6.4E-51 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily APE_1929.1 8038edb92076ce9d8e1332c6a9b55d72 222 Gene3D G3DSA:3.10.28.10 5 179 1.0E-11 T 23-10-2018 IPR027434 Homing endonuclease APE_1929.1 8038edb92076ce9d8e1332c6a9b55d72 222 SUPERFAMILY SSF55608 8 78 2.47E-5 T 23-10-2018 IPR027434 Homing endonuclease APE_1929.1 8038edb92076ce9d8e1332c6a9b55d72 222 Pfam PF14528 LAGLIDADG-like domain 109 183 1.3E-9 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 APE_1929.1 8038edb92076ce9d8e1332c6a9b55d72 222 SUPERFAMILY SSF55608 96 196 4.89E-13 T 23-10-2018 IPR027434 Homing endonuclease APE_0947 c7c510e9a76ac2609b2c789d4165d4ea 117 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 102 2.9E-7 T 23-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0947 c7c510e9a76ac2609b2c789d4165d4ea 117 SUPERFAMILY SSF81343 6 112 2.18E-9 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0947 c7c510e9a76ac2609b2c789d4165d4ea 117 Gene3D G3DSA:1.20.1300.10 1 113 1.5E-6 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_1550.1 74aed790c3bec430119fe0f23ada8779 374 Pfam PF12698 ABC-2 family transporter protein 29 361 4.4E-11 T 23-10-2018 APE_0641 c09f1ee1ee82338671e4c22855615f11 349 Pfam PF00085 Thioredoxin 242 334 5.3E-6 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 APE_0641 c09f1ee1ee82338671e4c22855615f11 349 ProSitePatterns PS00194 Thioredoxin family active site. 257 275 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 APE_0641 c09f1ee1ee82338671e4c22855615f11 349 Gene3D G3DSA:3.40.30.10 223 349 1.0E-28 T 23-10-2018 APE_0641 c09f1ee1ee82338671e4c22855615f11 349 SUPERFAMILY SSF52833 232 335 3.3E-13 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_0428.1 850104aa011bb63052255621a60de1da 600 Gene3D G3DSA:3.30.230.10 26 190 2.6E-8 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup APE_0428.1 850104aa011bb63052255621a60de1da 600 SUPERFAMILY SSF54211 32 190 4.55E-12 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold APE_0915.1 1a1846ea30438e93f518e5c25b0d3aa4 355 Pfam PF02163 Peptidase family M50 240 283 4.1E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 SUPERFAMILY SSF55729 506 630 2.27E-12 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 15 781 44.671 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Gene3D G3DSA:3.40.630.30 432 635 9.1E-56 T 23-10-2018 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Pfam PF13718 GNAT acetyltransferase 2 590 637 7.8E-9 T 23-10-2018 IPR000182 GNAT domain APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Pfam PF13718 GNAT acetyltransferase 2 470 585 6.4E-29 T 23-10-2018 IPR000182 GNAT domain APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Pfam PF13725 Possible tRNA binding domain 690 787 1.2E-8 T 23-10-2018 IPR027992 Possible tRNA binding domain Reactome: R-HSA-6790901 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Gene3D G3DSA:3.40.50.12320 246 419 3.1E-32 T 23-10-2018 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 SUPERFAMILY SSF52540 219 374 2.09E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Pfam PF05127 Helicase 250 429 1.2E-55 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Gene3D G3DSA:3.40.50.11040 66 213 5.3E-9 T 23-10-2018 APE_2392.1 166e418297be5fa0e2c3f7b4ecb00367 815 Pfam PF08351 Domain of unknown function (DUF1726) 92 184 4.6E-30 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 APE_0525a ca47237c0fd4e00090a1b1b6b50e55a9 77 Pfam PF01423 LSM domain 14 75 4.2E-19 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type APE_0525a ca47237c0fd4e00090a1b1b6b50e55a9 77 SMART SM00651 11 75 1.1E-21 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type APE_0525a ca47237c0fd4e00090a1b1b6b50e55a9 77 SUPERFAMILY SSF50182 7 75 8.59E-19 T 23-10-2018 IPR010920 LSM domain superfamily APE_0525a ca47237c0fd4e00090a1b1b6b50e55a9 77 Hamap MF_00257 Putative snRNP Sm-like protein. 5 75 23.573 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea APE_0525a ca47237c0fd4e00090a1b1b6b50e55a9 77 Gene3D G3DSA:2.30.30.100 5 76 3.3E-20 T 23-10-2018 APE_2581 0bbf8bfb63b80f6f585a70aa15b070ef 405 Gene3D G3DSA:3.30.930.10 35 291 2.2E-14 T 23-10-2018 APE_2581 0bbf8bfb63b80f6f585a70aa15b070ef 405 SUPERFAMILY SSF55681 59 282 5.87E-19 T 23-10-2018 APE_2581 0bbf8bfb63b80f6f585a70aa15b070ef 405 Gene3D G3DSA:3.30.390.50 309 394 2.1E-11 T 23-10-2018 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 2 88 29.97 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 Gene3D G3DSA:3.40.1800.40 30 87 1.0E-15 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 Pfam PF01199 Ribosomal protein L34e 3 86 5.8E-27 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 PRINTS PR01250 Ribosomal protein L34 signature 6 19 4.4E-20 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 PRINTS PR01250 Ribosomal protein L34 signature 19 36 4.4E-20 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 PRINTS PR01250 Ribosomal protein L34 signature 57 79 4.4E-20 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 PRINTS PR01250 Ribosomal protein L34 signature 37 47 4.4E-20 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0978a f9967c882efbcdeda2281ba7e81de2f6 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 8 21 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1262 6472f3b69f2930f8cae0833d6d87f918 286 SUPERFAMILY SSF161111 6 191 1.44E-15 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APE_1262 6472f3b69f2930f8cae0833d6d87f918 286 Gene3D G3DSA:1.20.1510.10 2 190 2.7E-14 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APE_1262 6472f3b69f2930f8cae0833d6d87f918 286 Pfam PF01545 Cation efflux family 8 189 4.6E-13 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 APE_0600 8910480a402bf8284586a5931fd70e9a 175 Gene3D G3DSA:3.90.79.10 5 160 3.2E-24 T 23-10-2018 APE_0600 8910480a402bf8284586a5931fd70e9a 175 SUPERFAMILY SSF55811 6 162 5.82E-25 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 APE_0600 8910480a402bf8284586a5931fd70e9a 175 Pfam PF00293 NUDIX domain 9 126 4.8E-17 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 APE_0503.1 e78c6eb23e7ef37024d0b567515fbe32 143 PIRSF PIRSF008210 1 143 2.0E-67 T 23-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 APE_0503.1 e78c6eb23e7ef37024d0b567515fbe32 143 Pfam PF09921 Uncharacterized protein conserved in archaea (DUF2153) 14 135 2.0E-50 T 23-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 APE_0071.1 9dcc3c6c54a89ff806c474beaa87af63 219 Gene3D G3DSA:3.90.420.10 20 209 8.6E-47 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 APE_0071.1 9dcc3c6c54a89ff806c474beaa87af63 219 SUPERFAMILY SSF56524 19 193 6.15E-53 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 APE_0071.1 9dcc3c6c54a89ff806c474beaa87af63 219 Pfam PF00174 Oxidoreductase molybdopterin binding domain 32 175 3.8E-32 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 APE_1230 332de4bf2aed6c2797ccd5705399281c 374 TIGRFAM TIGR01914 cas_Csa4: CRISPR-associated protein Cas8a2/Csa4, subtype I-A/APERN 2 369 5.4E-136 T 23-10-2018 IPR010184 CRISPR-associated protein, MJ0385 APE_1230 332de4bf2aed6c2797ccd5705399281c 374 Pfam PF09703 CRISPR-associated protein (Cas_Csa4) 3 368 7.2E-119 T 23-10-2018 IPR010184 CRISPR-associated protein, MJ0385 APE_0168.1 06163870c4303f51478af378c7c69789 127 Pfam PF01381 Helix-turn-helix 27 62 1.6E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 Gene3D G3DSA:3.40.50.300 18 355 1.2E-99 T 23-10-2018 APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 SUPERFAMILY SSF50249 125 207 7.37E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 Gene3D G3DSA:2.40.50.360 119 246 1.2E-99 T 23-10-2018 APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 SUPERFAMILY SSF52540 37 439 1.19E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 Gene3D G3DSA:1.10.8.60 360 449 4.5E-30 T 23-10-2018 APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 SMART SM00382 62 383 3.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0326.1 0fdc68ad900a7bee7b2bf444284c5389 449 Pfam PF06068 TIP49 C-terminus 16 409 8.3E-163 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 APE_1570 91b5c4f3ebad220a1b0d9415433d6426 284 Gene3D G3DSA:1.20.120.1780 159 284 4.5E-44 T 23-10-2018 APE_1570 91b5c4f3ebad220a1b0d9415433d6426 284 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 2 277 3.7E-69 T 23-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related APE_1570 91b5c4f3ebad220a1b0d9415433d6426 284 Pfam PF01040 UbiA prenyltransferase family 13 249 1.2E-37 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 APE_1570 91b5c4f3ebad220a1b0d9415433d6426 284 Gene3D G3DSA:1.10.357.140 3 158 3.1E-57 T 23-10-2018 APE_1209e 575d5abe9fbfc32400b0ea43a54b2125 91 SUPERFAMILY SSF47203 2 89 1.61E-20 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_1209e 575d5abe9fbfc32400b0ea43a54b2125 91 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 2 88 1.2E-16 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_1209e 575d5abe9fbfc32400b0ea43a54b2125 91 Gene3D G3DSA:1.20.140.10 1 91 9.1E-20 T 23-10-2018 APE_0677.1 bd2fc547066c04c482530b94f7e9f025 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 170 291 1.9E-26 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain APE_0677.1 bd2fc547066c04c482530b94f7e9f025 309 Gene3D G3DSA:3.40.50.720 3 166 2.8E-13 T 23-10-2018 APE_0677.1 bd2fc547066c04c482530b94f7e9f025 309 SUPERFAMILY SSF48179 170 291 5.44E-23 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APE_0677.1 bd2fc547066c04c482530b94f7e9f025 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 4 294 8.9E-63 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 APE_0677.1 bd2fc547066c04c482530b94f7e9f025 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 143 2.5E-14 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain APE_0677.1 bd2fc547066c04c482530b94f7e9f025 309 Gene3D G3DSA:1.10.1040.10 171 294 3.0E-25 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APE_2462.1 355a12355370592c19596fcbfb36891a 145 SMART SM00756 1 139 3.1E-17 T 23-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 APE_2462.1 355a12355370592c19596fcbfb36891a 145 Gene3D G3DSA:1.20.1440.130 2 143 3.5E-9 T 23-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 APE_2462.1 355a12355370592c19596fcbfb36891a 145 Pfam PF07884 Vitamin K epoxide reductase family 8 135 3.3E-19 T 23-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 APE_1080.1 b5f0facd5249347b081aafc1d0f4cb57 235 SUPERFAMILY SSF53271 86 216 1.31E-18 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like APE_1080.1 b5f0facd5249347b081aafc1d0f4cb57 235 Gene3D G3DSA:3.40.50.2020 66 232 4.1E-19 T 23-10-2018 APE_1080.1 b5f0facd5249347b081aafc1d0f4cb57 235 Pfam PF00156 Phosphoribosyl transferase domain 111 210 4.0E-6 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 APE_1260 a59ad6628f9917de85896b0af55d4664 209 SUPERFAMILY SSF56281 13 205 1.2E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1260 a59ad6628f9917de85896b0af55d4664 209 Gene3D G3DSA:3.60.15.10 3 209 2.9E-52 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1260 a59ad6628f9917de85896b0af55d4664 209 Pfam PF00753 Metallo-beta-lactamase superfamily 10 188 1.8E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_1260 a59ad6628f9917de85896b0af55d4664 209 SMART SM00849 13 188 3.2E-36 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0560 7a8072837b21337e8c53942361419979 483 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 28 367 1.9E-144 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 APE_0560 7a8072837b21337e8c53942361419979 483 PIRSF PIRSF016666 1 483 9.2E-233 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 APE_2380.1 cbcb668ae91bc025ce573b8309d9a355 79 Pfam PF02667 Short chain fatty acid transporter 6 77 6.7E-26 T 23-10-2018 IPR006160 Short chain fatty acid transporter AtoE APE_1031.1 b29adb4c97c4675a0a14d4305c0d692f 463 Pfam PF13519 von Willebrand factor type A domain 299 407 3.8E-9 T 23-10-2018 IPR002035 von Willebrand factor, type A APE_1031.1 b29adb4c97c4675a0a14d4305c0d692f 463 SUPERFAMILY SSF53300 298 441 2.23E-19 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_1031.1 b29adb4c97c4675a0a14d4305c0d692f 463 SMART SM00327 295 461 1.5E-9 T 23-10-2018 IPR002035 von Willebrand factor, type A APE_1031.1 b29adb4c97c4675a0a14d4305c0d692f 463 Gene3D G3DSA:3.40.50.410 299 453 3.9E-16 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_0667 481c1af8efbf9b5a0f25ea23a7620c57 395 SUPERFAMILY SSF140914 60 294 1.57E-15 T 23-10-2018 APE_1047.1 9496368350668a0045977ef7573d4cab 284 SUPERFAMILY SSF100950 6 260 1.42E-41 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_1047.1 9496368350668a0045977ef7573d4cab 284 Gene3D G3DSA:3.40.50.10470 93 263 7.7E-29 T 23-10-2018 APE_1047.1 9496368350668a0045977ef7573d4cab 284 Pfam PF01008 Initiation factor 2 subunit family 74 219 3.0E-23 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 APE_2035.1 0ec80ca56429856553be17af0ee15e3f 354 Gene3D G3DSA:3.90.1150.10 11 335 1.0E-75 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2035.1 0ec80ca56429856553be17af0ee15e3f 354 SUPERFAMILY SSF53383 4 350 4.99E-60 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2035.1 0ec80ca56429856553be17af0ee15e3f 354 Gene3D G3DSA:3.40.640.10 22 250 1.0E-75 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2035.1 0ec80ca56429856553be17af0ee15e3f 354 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 201 214 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APE_2035.1 0ec80ca56429856553be17af0ee15e3f 354 Pfam PF00155 Aminotransferase class I and II 13 346 1.3E-35 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APE_0500.1 fa9dc9f04d1407cf057cf79c82709451 294 Hamap MF_01406 UPF0282 protein . 1 290 39.215 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase APE_0500.1 fa9dc9f04d1407cf057cf79c82709451 294 PIRSF PIRSF004944 1 294 1.5E-110 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase APE_0500.1 fa9dc9f04d1407cf057cf79c82709451 294 SUPERFAMILY SSF56281 17 269 4.35E-11 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0500.1 fa9dc9f04d1407cf057cf79c82709451 294 Gene3D G3DSA:3.60.15.10 13 248 2.6E-9 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_1583.1 db368b66f34661c7b7be3bfed9e3c6e5 915 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 105 239 1.3E-9 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain APE_1583.1 db368b66f34661c7b7be3bfed9e3c6e5 915 SUPERFAMILY SSF53850 158 454 1.57E-11 T 23-10-2018 APE_1583.1 db368b66f34661c7b7be3bfed9e3c6e5 915 SUPERFAMILY SSF53850 585 791 2.35E-6 T 23-10-2018 APE_1241.1 5d7e87fbd9e5746fb115c3435df403c2 260 Pfam PF06023 CRISPR-associated exonuclease Csa1 4 87 1.0E-24 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 APE_1241.1 5d7e87fbd9e5746fb115c3435df403c2 260 Pfam PF06023 CRISPR-associated exonuclease Csa1 89 259 9.8E-62 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 APE_1241.1 5d7e87fbd9e5746fb115c3435df403c2 260 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 6 258 4.1E-89 T 23-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 APE_2379 e5a4d6ea10e708b3d357de1aed52f92f 221 Pfam PF01810 LysE type translocator 21 210 7.3E-21 T 23-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 APE_2568.1 705dc52cad890e646731ad8d66208256 190 Gene3D G3DSA:3.40.30.10 27 190 4.0E-43 T 23-10-2018 APE_2568.1 705dc52cad890e646731ad8d66208256 190 Pfam PF00578 AhpC/TSA family 44 109 1.4E-6 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 APE_2568.1 705dc52cad890e646731ad8d66208256 190 SUPERFAMILY SSF52833 44 189 1.28E-21 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1548.1 70f0fd20139e8a001779fa09d9d1c995 300 SMART SM00382 29 212 7.4E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1548.1 70f0fd20139e8a001779fa09d9d1c995 300 SUPERFAMILY SSF52540 5 226 1.43E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1548.1 70f0fd20139e8a001779fa09d9d1c995 300 Gene3D G3DSA:3.40.50.300 3 233 1.4E-65 T 23-10-2018 APE_1548.1 70f0fd20139e8a001779fa09d9d1c995 300 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1548.1 70f0fd20139e8a001779fa09d9d1c995 300 Pfam PF00005 ABC transporter 22 163 8.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2426.1 e227dea0877b6f05206aa15cd895b182 363 Pfam PF00999 Sodium/hydrogen exchanger family 12 354 1.8E-50 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 APE_2426.1 e227dea0877b6f05206aa15cd895b182 363 Gene3D G3DSA:1.20.1530.20 6 363 3.6E-48 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily APE_1820 566a93ec670777a578e486662819d32d 470 Gene3D G3DSA:3.50.50.60 1 103 4.6E-10 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1820 566a93ec670777a578e486662819d32d 470 Pfam PF12831 FAD dependent oxidoreductase 5 51 9.0E-10 T 23-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal APE_1820 566a93ec670777a578e486662819d32d 470 SUPERFAMILY SSF51905 3 440 5.59E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1422 e863403dc5fda2fdb879f5162a7b13f2 414 Gene3D G3DSA:1.10.645.20 30 414 1.1E-122 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1422 e863403dc5fda2fdb879f5162a7b13f2 414 SUPERFAMILY SSF56762 42 414 3.53E-104 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1422 e863403dc5fda2fdb879f5162a7b13f2 414 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 143 414 7.8E-85 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_1571.1 d7f424b8b8e68ba2cda26f4f8e2107db 487 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 453 1.1E-120 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 APE_1571.1 d7f424b8b8e68ba2cda26f4f8e2107db 487 SUPERFAMILY SSF50475 5 321 3.61E-90 T 23-10-2018 APE_1571.1 d7f424b8b8e68ba2cda26f4f8e2107db 487 Gene3D G3DSA:3.40.1670.10 336 452 1.0E-40 T 23-10-2018 APE_1571.1 d7f424b8b8e68ba2cda26f4f8e2107db 487 SUPERFAMILY SSF143968 322 486 3.01E-57 T 23-10-2018 APE_1571.1 d7f424b8b8e68ba2cda26f4f8e2107db 487 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 427 4.0E-129 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 APE_0601 dc49d03e62bffc7e1c3ccc07521afa9c 184 SUPERFAMILY SSF56784 29 98 1.02E-10 T 23-10-2018 IPR036412 HAD-like superfamily APE_0601 dc49d03e62bffc7e1c3ccc07521afa9c 184 Gene3D G3DSA:3.40.50.1000 31 154 2.3E-6 T 23-10-2018 IPR023214 HAD superfamily APE_2290.1 150ce8ab22a6ce57764335e38a571da7 639 Pfam PF07676 WD40-like Beta Propeller Repeat 65 90 2.4E-5 T 23-10-2018 IPR011659 WD40-like Beta Propeller APE_2290.1 150ce8ab22a6ce57764335e38a571da7 639 SUPERFAMILY SSF69304 63 295 6.28E-12 T 23-10-2018 APE_2290.1 150ce8ab22a6ce57764335e38a571da7 639 Pfam PF00326 Prolyl oligopeptidase family 412 620 1.9E-51 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 APE_2290.1 150ce8ab22a6ce57764335e38a571da7 639 Gene3D G3DSA:2.120.10.30 18 238 7.5E-8 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like APE_2290.1 150ce8ab22a6ce57764335e38a571da7 639 SUPERFAMILY SSF53474 369 620 1.34E-56 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2290.1 150ce8ab22a6ce57764335e38a571da7 639 Gene3D G3DSA:3.40.50.1820 370 621 1.6E-63 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_2041.1 4d6e718e6b1ecacfbcca7d79ba0e06da 318 Pfam PF00733 Asparagine synthase 26 151 2.0E-21 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 APE_2041.1 4d6e718e6b1ecacfbcca7d79ba0e06da 318 SUPERFAMILY SSF52402 13 240 1.15E-31 T 23-10-2018 APE_2041.1 4d6e718e6b1ecacfbcca7d79ba0e06da 318 Gene3D G3DSA:3.40.50.620 6 247 1.1E-36 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0880b 7fa77dba49dc90f22bc286ff0da757a5 81 SUPERFAMILY SSF46785 12 75 9.76E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0880b 7fa77dba49dc90f22bc286ff0da757a5 81 Gene3D G3DSA:1.10.10.10 2 80 1.2E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0880b 7fa77dba49dc90f22bc286ff0da757a5 81 Pfam PF09339 IclR helix-turn-helix domain 11 57 6.2E-9 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 APE_0338.1 0240426716e0589b5b4904fa11238ff7 456 Pfam PF00144 Beta-lactamase 12 327 8.2E-60 T 23-10-2018 IPR001466 Beta-lactamase-related APE_0338.1 0240426716e0589b5b4904fa11238ff7 456 Gene3D G3DSA:3.40.710.10 5 342 4.3E-92 T 23-10-2018 APE_0338.1 0240426716e0589b5b4904fa11238ff7 456 SUPERFAMILY SSF56601 4 331 5.31E-68 T 23-10-2018 IPR012338 Beta-lactamase/transpeptidase-like APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 SUPERFAMILY SSF52540 48 318 6.43E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 Pfam PF01926 50S ribosome-binding GTPase 164 284 1.0E-15 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 Gene3D G3DSA:3.40.50.300 155 336 4.3E-32 T 23-10-2018 APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 185 203 1.8E-9 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 164 184 1.8E-9 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 1.8E-9 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_0510.1 bf46145f7d65ce7b84189b1903225caf 341 Gene3D G3DSA:1.20.120.1190 7 154 3.9E-16 T 23-10-2018 APE_1234.1 e893ca4904aa36cb096800969eaa2ed1 282 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 8 196 1.5E-75 T 23-10-2018 IPR010153 CRISPR-associated protein, Cas5a type APE_1234.1 e893ca4904aa36cb096800969eaa2ed1 282 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 8 44 5.7E-10 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal APE_0471a 27bb711aa427efbdf103977b35f1b100 106 SUPERFAMILY SSF88723 5 92 1.77E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_0471a 27bb711aa427efbdf103977b35f1b100 106 Pfam PF01850 PIN domain 4 86 2.4E-9 T 23-10-2018 IPR002716 PIN domain APE_0471a 27bb711aa427efbdf103977b35f1b100 106 Gene3D G3DSA:3.40.50.1010 3 97 1.0E-7 T 23-10-2018 APE_0786.1 63075a1b1b9d35e5937f156ecfdf7ea6 133 Gene3D G3DSA:2.40.10.230 20 102 1.7E-9 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain APE_0786.1 63075a1b1b9d35e5937f156ecfdf7ea6 133 SUPERFAMILY SSF50447 26 89 1.52E-7 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily APE_0142 7fb8c0796a2c58bdb5b932f3eeb42845 180 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 23 76 2.6E-9 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 APE_0142 7fb8c0796a2c58bdb5b932f3eeb42845 180 SUPERFAMILY SSF47979 80 154 1.45E-13 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 APE_0142 7fb8c0796a2c58bdb5b932f3eeb42845 180 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 80 147 9.5E-10 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 APE_0142 7fb8c0796a2c58bdb5b932f3eeb42845 180 SMART SM00529 41 139 2.3E-35 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 APE_0142 7fb8c0796a2c58bdb5b932f3eeb42845 180 Gene3D G3DSA:1.10.10.10 10 148 4.2E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0142 7fb8c0796a2c58bdb5b932f3eeb42845 180 SUPERFAMILY SSF46785 25 91 2.64E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1443a a0fff235954072733908a7264ba3d29d 86 Pfam PF01780 Ribosomal L37ae protein family 3 85 2.8E-32 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1443a a0fff235954072733908a7264ba3d29d 86 Gene3D G3DSA:2.20.25.30 1 86 1.3E-27 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1443a a0fff235954072733908a7264ba3d29d 86 SUPERFAMILY SSF57829 10 81 2.2E-24 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 APE_1443a a0fff235954072733908a7264ba3d29d 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 72 24.068 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_1026.1 b3a003fb89162c019634673f91b0b4d8 211 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1026.1 b3a003fb89162c019634673f91b0b4d8 211 SUPERFAMILY SSF52540 4 208 4.87E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1026.1 b3a003fb89162c019634673f91b0b4d8 211 Gene3D G3DSA:3.40.50.300 2 211 8.7E-43 T 23-10-2018 APE_1026.1 b3a003fb89162c019634673f91b0b4d8 211 Pfam PF00005 ABC transporter 20 156 3.8E-19 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1026.1 b3a003fb89162c019634673f91b0b4d8 211 SMART SM00382 29 209 2.5E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0302.1 58a013eb82f064bd954d3368c818760f 301 SUPERFAMILY SSF161098 89 278 1.57E-25 T 23-10-2018 IPR035906 MetI-like superfamily APE_0302.1 58a013eb82f064bd954d3368c818760f 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 56 2.0E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain APE_0302.1 58a013eb82f064bd954d3368c818760f 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 296 1.4E-30 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_0302.1 58a013eb82f064bd954d3368c818760f 301 Gene3D G3DSA:1.10.3720.10 86 297 2.3E-19 T 23-10-2018 IPR035906 MetI-like superfamily APE_1856a ed78e48f06d1c7206dee22637fbbacf4 90 Gene3D G3DSA:3.90.940.20 2 84 3.6E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1856a ed78e48f06d1c7206dee22637fbbacf4 90 SUPERFAMILY SSF55287 12 83 2.09E-25 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1856a ed78e48f06d1c7206dee22637fbbacf4 90 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 12 82 6.9E-29 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1856a ed78e48f06d1c7206dee22637fbbacf4 90 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 16 82 3.0E-33 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1856a ed78e48f06d1c7206dee22637fbbacf4 90 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 10 83 22.052 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_1856a ed78e48f06d1c7206dee22637fbbacf4 90 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 15 28 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 APE_0781.1 1bfe1fa150ce55829f491d0bebef5035 206 Pfam PF03266 NTPase 20 188 5.0E-53 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 APE_0781.1 1bfe1fa150ce55829f491d0bebef5035 206 Hamap MF_00796 Nucleoside-triphosphatase . 18 198 27.606 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 APE_0781.1 1bfe1fa150ce55829f491d0bebef5035 206 Gene3D G3DSA:3.40.50.300 17 196 9.6E-34 T 23-10-2018 APE_0781.1 1bfe1fa150ce55829f491d0bebef5035 206 SUPERFAMILY SSF52540 20 193 2.08E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0275a 088c05ad2d66258f492180075d1b3806 75 Pfam PF10049 Protein of unknown function (DUF2283) 7 54 8.4E-20 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 APE_0546a aac8ff6084ad105d2d8e59f86bcbb78a 107 Gene3D G3DSA:2.30.30.70 3 98 3.6E-32 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0546a aac8ff6084ad105d2d8e59f86bcbb78a 107 ProSitePatterns PS01171 Ribosomal protein L21e signature. 39 65 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0546a aac8ff6084ad105d2d8e59f86bcbb78a 107 SUPERFAMILY SSF50104 5 98 4.21E-28 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily APE_0546a aac8ff6084ad105d2d8e59f86bcbb78a 107 Pfam PF01157 Ribosomal protein L21e 6 97 1.0E-29 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0546a aac8ff6084ad105d2d8e59f86bcbb78a 107 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 99 28.108 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal APE_0639.1 716fec02c6a1a5ef34a53de2d16510d6 130 Pfam PF02675 S-adenosylmethionine decarboxylase 22 127 5.9E-33 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APE_0639.1 716fec02c6a1a5ef34a53de2d16510d6 130 SUPERFAMILY SSF56276 17 127 4.71E-33 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 APE_0639.1 716fec02c6a1a5ef34a53de2d16510d6 130 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 16 130 28.359 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APE_0639.1 716fec02c6a1a5ef34a53de2d16510d6 130 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 18 127 2.6E-34 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APE_0639.1 716fec02c6a1a5ef34a53de2d16510d6 130 Gene3D G3DSA:3.60.90.10 6 129 2.0E-34 T 23-10-2018 APE_0702.1 8dfc15024659509d80b939544bc567e9 137 Pfam PF02195 ParB-like nuclease domain 6 70 7.2E-8 T 23-10-2018 IPR003115 ParB/Sulfiredoxin APE_0702.1 8dfc15024659509d80b939544bc567e9 137 SMART SM00470 1 91 1.5E-11 T 23-10-2018 IPR003115 ParB/Sulfiredoxin APE_0702.1 8dfc15024659509d80b939544bc567e9 137 SUPERFAMILY SSF110849 2 123 2.75E-34 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily APE_0702.1 8dfc15024659509d80b939544bc567e9 137 Gene3D G3DSA:3.90.1530.10 1 89 1.1E-24 T 23-10-2018 APE_1258.1 300326ee09e09ebbe488a88f735f7466 184 Gene3D G3DSA:1.20.120.520 5 160 3.3E-26 T 23-10-2018 APE_1258.1 300326ee09e09ebbe488a88f735f7466 184 Pfam PF01814 Hemerythrin HHE cation binding domain 8 142 1.1E-20 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 APE_1882.1 a4b81a3294152d08de0a36a9035e3ead 812 Gene3D G3DSA:2.115.10.20 273 520 2.6E-6 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily APE_1882.1 a4b81a3294152d08de0a36a9035e3ead 812 SUPERFAMILY SSF50939 98 463 3.33E-29 T 23-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 APE_1882.1 a4b81a3294152d08de0a36a9035e3ead 812 Gene3D G3DSA:2.130.10.10 83 272 5.8E-9 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 APE_1882.1 a4b81a3294152d08de0a36a9035e3ead 812 Gene3D G3DSA:1.20.120.20 660 791 6.8E-6 T 23-10-2018 APE_0513.1 e6204d98467904806d1932c7a01a5d78 172 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 59 8.9E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APE_0513.1 e6204d98467904806d1932c7a01a5d78 172 SUPERFAMILY SSF52374 2 167 6.97E-30 T 23-10-2018 APE_0513.1 e6204d98467904806d1932c7a01a5d78 172 Gene3D G3DSA:3.40.50.620 2 172 2.0E-38 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_0513.1 e6204d98467904806d1932c7a01a5d78 172 Pfam PF01467 Cytidylyltransferase-like 5 135 1.3E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 APE_0513.1 e6204d98467904806d1932c7a01a5d78 172 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 172 72.171 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 APE_1191 53ad2c08f677ec8d5c0681699bacc6cc 363 Gene3D G3DSA:3.40.50.2000 13 351 5.3E-76 T 23-10-2018 APE_1191 53ad2c08f677ec8d5c0681699bacc6cc 363 Pfam PF00534 Glycosyl transferases group 1 180 339 1.6E-42 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 APE_1191 53ad2c08f677ec8d5c0681699bacc6cc 363 Gene3D G3DSA:3.40.50.2000 172 341 5.3E-76 T 23-10-2018 APE_1191 53ad2c08f677ec8d5c0681699bacc6cc 363 Pfam PF13439 Glycosyltransferase Family 4 16 176 2.4E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 APE_1191 53ad2c08f677ec8d5c0681699bacc6cc 363 SUPERFAMILY SSF53756 13 360 1.38E-87 T 23-10-2018 APE_0938.1 19e68821438108a0076374390c236c0e 228 Gene3D G3DSA:1.10.510.10 98 207 4.5E-9 T 23-10-2018 APE_0938.1 19e68821438108a0076374390c236c0e 228 SUPERFAMILY SSF56112 8 192 3.49E-18 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily APE_1615 21024ca8e3e8956cff686f24dc7077a0 351 Pfam PF01545 Cation efflux family 53 247 1.0E-14 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 APE_1615 21024ca8e3e8956cff686f24dc7077a0 351 SUPERFAMILY SSF161111 50 248 1.19E-6 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily APE_0079 8c02964ced21e1cea09f2b699cf9c2f0 132 Gene3D G3DSA:3.60.90.10 1 131 8.3E-35 T 23-10-2018 APE_0079 8c02964ced21e1cea09f2b699cf9c2f0 132 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 6 124 26.13 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APE_0079 8c02964ced21e1cea09f2b699cf9c2f0 132 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 8 120 3.7E-40 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APE_0079 8c02964ced21e1cea09f2b699cf9c2f0 132 Pfam PF02675 S-adenosylmethionine decarboxylase 12 119 2.2E-32 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 APE_0079 8c02964ced21e1cea09f2b699cf9c2f0 132 SUPERFAMILY SSF56276 8 122 1.65E-35 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 APE_0079 8c02964ced21e1cea09f2b699cf9c2f0 132 Hamap MF_01298 Arginine decarboxylase proenzyme. 2 121 48.536 T 23-10-2018 IPR027549 Arginine decarboxylase proenzyme GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 APE_2336a eaf248504399c79237e6c079c8287688 91 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 23 90 7.0E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 APE_2336a eaf248504399c79237e6c079c8287688 91 Pfam PF03685 Uncharacterised protein family (UPF0147) 10 89 4.5E-34 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 APE_2336a eaf248504399c79237e6c079c8287688 91 Gene3D G3DSA:1.20.1440.50 8 91 1.5E-29 T 23-10-2018 IPR023130 Ta0600-like superfamily APE_2336a eaf248504399c79237e6c079c8287688 91 SUPERFAMILY SSF158436 7 91 6.02E-32 T 23-10-2018 APE_2336a eaf248504399c79237e6c079c8287688 91 Hamap MF_00342 UPF0147 protein . 9 90 29.948 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 APE_2086 c6623856dfecdcf5b0b6a50f5a57b9c9 331 Pfam PF01171 PP-loop family 51 210 1.4E-10 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 APE_2086 c6623856dfecdcf5b0b6a50f5a57b9c9 331 SUPERFAMILY SSF52402 26 235 1.1E-41 T 23-10-2018 APE_2086 c6623856dfecdcf5b0b6a50f5a57b9c9 331 Gene3D G3DSA:3.40.50.620 2 303 1.4E-63 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_2086 c6623856dfecdcf5b0b6a50f5a57b9c9 331 PIRSF PIRSF004976 1 306 2.6E-92 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 APE_0594a.1 d267ad752608776ee3b8d61196ed953e 92 SUPERFAMILY SSF46785 8 89 2.77E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0594a.1 d267ad752608776ee3b8d61196ed953e 92 Pfam PF14947 Winged helix-turn-helix 6 86 5.8E-15 T 23-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain APE_0594a.1 d267ad752608776ee3b8d61196ed953e 92 Gene3D G3DSA:1.10.10.10 2 90 2.0E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2291 3c35dc6c2e12f5144b981bb4955c6a80 239 Pfam PF00483 Nucleotidyl transferase 3 228 4.6E-35 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 APE_2291 3c35dc6c2e12f5144b981bb4955c6a80 239 Gene3D G3DSA:3.90.550.10 2 230 6.0E-64 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_2291 3c35dc6c2e12f5144b981bb4955c6a80 239 SUPERFAMILY SSF53448 2 227 5.42E-62 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0275b.1 885de9235946e6a951ff8bd46cb56f49 108 SUPERFAMILY SSF53167 6 103 1.44E-10 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APE_0275b.1 885de9235946e6a951ff8bd46cb56f49 108 Gene3D G3DSA:3.40.50.1580 2 108 1.3E-10 T 23-10-2018 APE_0275b.1 885de9235946e6a951ff8bd46cb56f49 108 Pfam PF01048 Phosphorylase superfamily 47 86 7.0E-8 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 APE_0313.1 f3af2b1446ad78d685196e384ebc43b7 164 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 3 135 4.6E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain APE_0313.1 f3af2b1446ad78d685196e384ebc43b7 164 Pfam PF01980 Uncharacterised protein family UPF0066 26 135 6.4E-34 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain APE_0313.1 f3af2b1446ad78d685196e384ebc43b7 164 Gene3D G3DSA:2.40.30.70 3 148 1.1E-37 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily APE_0313.1 f3af2b1446ad78d685196e384ebc43b7 164 SUPERFAMILY SSF118196 3 153 3.27E-41 T 23-10-2018 IPR036413 YaeB-like superfamily APE_1255.1 ee51b86441b9ab2bdc0586e602ecace8 249 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 APE_1255.1 ee51b86441b9ab2bdc0586e602ecace8 249 SUPERFAMILY SSF52540 7 228 2.19E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1255.1 ee51b86441b9ab2bdc0586e602ecace8 249 Gene3D G3DSA:3.40.50.300 4 246 1.1E-59 T 23-10-2018 APE_1255.1 ee51b86441b9ab2bdc0586e602ecace8 249 Pfam PF00005 ABC transporter 24 166 8.1E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1255.1 ee51b86441b9ab2bdc0586e602ecace8 249 SMART SM00382 33 223 1.9E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1161.1 1b6bc26b742fc4e3ed900ab69a4c0726 123 Pfam PF01900 Rpp14/Pop5 family 14 109 3.1E-10 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 APE_1161.1 1b6bc26b742fc4e3ed900ab69a4c0726 123 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 2 115 22.259 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 APE_1161.1 1b6bc26b742fc4e3ed900ab69a4c0726 123 Gene3D G3DSA:3.30.70.3250 4 116 2.5E-21 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 APE_1161.1 1b6bc26b742fc4e3ed900ab69a4c0726 123 SUPERFAMILY SSF160350 10 113 3.66E-21 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 399 45.277 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 Gene3D G3DSA:1.10.8.60 310 388 1.1E-25 T 23-10-2018 APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 381 1.2E-198 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 Gene3D G3DSA:2.40.50.140 23 128 3.0E-26 T 23-10-2018 APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 SUPERFAMILY SSF52540 130 380 6.0E-73 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 Gene3D G3DSA:3.40.50.300 129 309 1.2E-68 T 23-10-2018 APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 SMART SM00382 172 311 1.8E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 APE_2012 604b8d1f52d93ee67211ff64a4ea78f2 409 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 2.2E-44 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 APE_1053.1 094f641b7218c4fbf2e339a3900dbfa3 320 Gene3D G3DSA:1.10.3470.10 2 316 8.7E-68 T 23-10-2018 IPR037294 ABC transporter, BtuC-like APE_1053.1 094f641b7218c4fbf2e339a3900dbfa3 320 SUPERFAMILY SSF81345 6 309 8.24E-58 T 23-10-2018 IPR037294 ABC transporter, BtuC-like APE_1053.1 094f641b7218c4fbf2e339a3900dbfa3 320 Pfam PF01032 FecCD transport family 44 310 2.6E-65 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 APE_2472.1 2e20531980508cb9c821913d1e24417f 291 Gene3D G3DSA:3.40.50.300 6 98 1.3E-5 T 23-10-2018 APE_2472.1 2e20531980508cb9c821913d1e24417f 291 SUPERFAMILY SSF52540 7 88 2.71E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1591.1 53b1aa5aec2b3c51f9d48553db1d4798 101 ProSitePatterns PS00150 Acylphosphatase signature 1. 18 28 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 APE_1591.1 53b1aa5aec2b3c51f9d48553db1d4798 101 Pfam PF00708 Acylphosphatase 15 99 1.4E-24 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 APE_1591.1 53b1aa5aec2b3c51f9d48553db1d4798 101 Gene3D G3DSA:3.30.70.100 2 101 8.4E-28 T 23-10-2018 APE_1591.1 53b1aa5aec2b3c51f9d48553db1d4798 101 SUPERFAMILY SSF54975 10 101 3.05E-27 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 APE_2365.1 6596fefead4a9fbf182e8dcdb2196a40 147 SUPERFAMILY SSF88723 12 135 8.97E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_2365.1 6596fefead4a9fbf182e8dcdb2196a40 147 Gene3D G3DSA:3.40.50.1010 10 140 2.1E-17 T 23-10-2018 APE_2365.1 6596fefead4a9fbf182e8dcdb2196a40 147 Pfam PF04900 Fcf1 37 140 2.0E-8 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 APE_2365.1 6596fefead4a9fbf182e8dcdb2196a40 147 SMART SM00670 11 120 8.5E-12 T 23-10-2018 IPR002716 PIN domain APE_1622.1 69a3a9b4dbf2cc3c837c45495b3d6b56 389 SUPERFAMILY SSF51905 3 288 1.17E-27 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1622.1 69a3a9b4dbf2cc3c837c45495b3d6b56 389 Gene3D G3DSA:3.50.50.60 3 323 2.6E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1622.1 69a3a9b4dbf2cc3c837c45495b3d6b56 389 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 146 1.8E-6 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_1622.1 69a3a9b4dbf2cc3c837c45495b3d6b56 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 238 253 1.1E-7 T 23-10-2018 APE_1622.1 69a3a9b4dbf2cc3c837c45495b3d6b56 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.1E-7 T 23-10-2018 APE_2109 5613635d96cf951de9cbec3fe44a8073 447 Gene3D G3DSA:3.80.30.20 157 378 7.3E-36 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe APE_2109 5613635d96cf951de9cbec3fe44a8073 447 Pfam PF02310 B12 binding domain 14 109 1.8E-11 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 APE_2109 5613635d96cf951de9cbec3fe44a8073 447 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 8 387 1.1E-111 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type APE_2109 5613635d96cf951de9cbec3fe44a8073 447 SUPERFAMILY SSF102114 142 367 2.22E-43 T 23-10-2018 APE_2109 5613635d96cf951de9cbec3fe44a8073 447 Pfam PF04055 Radical SAM superfamily 160 333 1.8E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_2109 5613635d96cf951de9cbec3fe44a8073 447 Gene3D G3DSA:3.40.50.280 2 120 2.8E-11 T 23-10-2018 APE_2109 5613635d96cf951de9cbec3fe44a8073 447 SMART SM00729 156 380 1.2E-54 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 APE_1313.1 22c145209d1c8ed8544698ab453e2700 178 Pfam PF13559 Domain of unknown function (DUF4129) 115 175 9.2E-7 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 APE_2176a 7b7713522a33cc53113447fb19a58272 60 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 8 57 9.5E-13 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_2176a 7b7713522a33cc53113447fb19a58272 60 Gene3D G3DSA:1.20.5.820 2 59 3.5E-16 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_2176a 7b7713522a33cc53113447fb19a58272 60 SUPERFAMILY SSF103456 8 57 1.83E-13 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_2176a 7b7713522a33cc53113447fb19a58272 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 5 60 11.153 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 Gene3D G3DSA:3.40.640.10 70 295 2.1E-97 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 97 117 6.3E-11 T 23-10-2018 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 119 140 6.3E-11 T 23-10-2018 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 234 258 6.3E-11 T 23-10-2018 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 203 226 6.3E-11 T 23-10-2018 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 167 191 6.3E-11 T 23-10-2018 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 Pfam PF00155 Aminotransferase class I and II 67 377 5.4E-37 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 240 253 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 SUPERFAMILY SSF53383 53 380 4.03E-63 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2575 7722fca5fef6a4a66ad9bfb3106b4ac8 397 Gene3D G3DSA:3.90.1150.10 35 378 2.1E-97 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_0287 8ca0587ced2220a5ea73af5dcf18ac5b 195 Pfam PF11563 Protoglobin 23 194 3.1E-35 T 23-10-2018 APE_0287 8ca0587ced2220a5ea73af5dcf18ac5b 195 PIRSF PIRSF014300 1 195 3.8E-126 T 23-10-2018 IPR012102 Protoglobin APE_0287 8ca0587ced2220a5ea73af5dcf18ac5b 195 Gene3D G3DSA:1.10.490.10 1 195 1.1E-76 T 23-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 APE_0287 8ca0587ced2220a5ea73af5dcf18ac5b 195 SUPERFAMILY SSF46458 10 186 1.09E-25 T 23-10-2018 IPR009050 Globin-like superfamily APE_1734.1 8b4be8022675c19b87a7ee73c7f6a088 174 SUPERFAMILY SSF75217 17 160 1.96E-10 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 Pfam PF13416 Bacterial extracellular solute-binding protein 55 319 7.3E-33 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 42 58 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 101 114 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 264 283 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 179 198 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 132 148 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 58 79 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 85 99 7.5E-24 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 SUPERFAMILY SSF53850 36 352 9.45E-75 T 23-10-2018 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 PIRSF PIRSF019574 2 370 1.2E-87 T 23-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 Gene3D G3DSA:3.40.190.10 39 340 3.2E-95 T 23-10-2018 APE_0945.1 459298ef626fbb3fad8eb1d68dedb086 404 Gene3D G3DSA:3.40.190.10 141 361 3.2E-95 T 23-10-2018 APE_0333.1 d2485a686b6500db044ecfdd4fe4cb99 178 Gene3D G3DSA:2.70.40.10 1 176 1.2E-45 T 23-10-2018 IPR036157 dUTPase-like superfamily APE_0333.1 d2485a686b6500db044ecfdd4fe4cb99 178 Hamap MF_00146 dCTP deaminase [dcd]. 1 172 31.377 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 APE_0333.1 d2485a686b6500db044ecfdd4fe4cb99 178 Pfam PF00692 dUTPase 62 166 8.9E-16 T 23-10-2018 IPR029054 dUTPase-like APE_0333.1 d2485a686b6500db044ecfdd4fe4cb99 178 SUPERFAMILY SSF51283 2 173 4.45E-42 T 23-10-2018 IPR036157 dUTPase-like superfamily APE_0333.1 d2485a686b6500db044ecfdd4fe4cb99 178 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 171 1.0E-48 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 290 43.926 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 Gene3D G3DSA:3.40.50.261 125 292 2.3E-74 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 153 182 - T 23-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 23-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 SUPERFAMILY SSF51735 1 123 2.18E-42 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 PRINTS PR01798 Succinyl-CoA synthase signature 209 222 1.3E-32 T 23-10-2018 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 1.3E-32 T 23-10-2018 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 PRINTS PR01798 Succinyl-CoA synthase signature 83 100 1.3E-32 T 23-10-2018 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 PRINTS PR01798 Succinyl-CoA synthase signature 178 196 1.3E-32 T 23-10-2018 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 SUPERFAMILY SSF52210 124 288 4.06E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 PIRSF PIRSF001553 1 292 1.7E-135 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 290 1.1E-127 T 23-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 Gene3D G3DSA:3.40.50.720 1 124 6.4E-54 T 23-10-2018 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 SMART SM00881 4 101 1.8E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 Pfam PF00549 CoA-ligase 152 272 4.7E-19 T 23-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 APE_1072.1 5a130cba78237a0f728ac993c05abd8e 292 Pfam PF02629 CoA binding domain 6 100 8.6E-32 T 23-10-2018 IPR003781 CoA-binding GO:0048037 APE_2460.1 05d2c0fdf13c1fb74a3fcf934c5a5dc2 92 PIRSF PIRSF036548 1 92 2.1E-32 T 23-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 APE_2460.1 05d2c0fdf13c1fb74a3fcf934c5a5dc2 92 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 38 89 4.9E-5 T 23-10-2018 APE_2460.1 05d2c0fdf13c1fb74a3fcf934c5a5dc2 92 SUPERFAMILY SSF54862 39 90 4.37E-10 T 23-10-2018 APE_2460.1 05d2c0fdf13c1fb74a3fcf934c5a5dc2 92 Gene3D G3DSA:3.30.70.20 8 86 1.6E-8 T 23-10-2018 APE_1594 9e62153efbda33a25b0a4f1366b0492e 267 Gene3D G3DSA:3.40.50.720 16 256 6.0E-71 T 23-10-2018 APE_1594 9e62153efbda33a25b0a4f1366b0492e 267 SUPERFAMILY SSF69572 18 248 5.89E-76 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 APE_1594 9e62153efbda33a25b0a4f1366b0492e 267 Pfam PF00899 ThiF family 23 246 4.3E-62 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 APE_0446 f7bac3afb188bf90601bb20d3294414e 219 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 132 138 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 APE_0446 f7bac3afb188bf90601bb20d3294414e 219 Pfam PF03602 Conserved hypothetical protein 95 40 159 4.5E-5 T 23-10-2018 APE_0446 f7bac3afb188bf90601bb20d3294414e 219 Gene3D G3DSA:3.40.50.150 17 217 1.4E-29 T 23-10-2018 APE_0446 f7bac3afb188bf90601bb20d3294414e 219 SUPERFAMILY SSF53335 35 207 1.31E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1703 934532eb6f39c0beea85763b0480c245 476 Pfam PF01458 Uncharacterized protein family (UPF0051) 220 445 6.8E-65 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 APE_1703 934532eb6f39c0beea85763b0480c245 476 SUPERFAMILY SSF101960 42 466 4.05E-124 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily APE_1703 934532eb6f39c0beea85763b0480c245 476 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 27 465 6.3E-189 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 Gene3D G3DSA:1.10.10.10 7 59 1.1E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 55 3.2E-11 T 23-10-2018 APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 SUPERFAMILY SSF46785 8 67 1.74E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 SMART SM00344 8 113 5.7E-5 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 8 24 3.6E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 35 54 3.6E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_2565.1 19b18c3fe9f2a2bb535f805da2417de2 206 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 24 35 3.6E-8 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_0973b baac95d024dfef8170307fdf82360363 57 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 5.2E-10 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 APE_0973b baac95d024dfef8170307fdf82360363 57 SUPERFAMILY SSF47598 4 41 2.83E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APE_0978.1 b3ac438888571ec1dd47e5df6e0d3c8e 172 Pfam PF13207 AAA domain 4 81 2.0E-15 T 23-10-2018 APE_0978.1 b3ac438888571ec1dd47e5df6e0d3c8e 172 Hamap MF_00239 Cytidylate kinase [cmk]. 1 171 42.86 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 APE_0978.1 b3ac438888571ec1dd47e5df6e0d3c8e 172 SUPERFAMILY SSF52540 1 165 1.17E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0978.1 b3ac438888571ec1dd47e5df6e0d3c8e 172 Gene3D G3DSA:3.40.50.300 1 172 2.1E-36 T 23-10-2018 APE_0978.1 b3ac438888571ec1dd47e5df6e0d3c8e 172 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 1 163 1.8E-46 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 APE_1878 8945ddc232ef18457cab898c343c5fe8 305 Pfam PF01040 UbiA prenyltransferase family 34 280 6.4E-46 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 APE_1878 8945ddc232ef18457cab898c343c5fe8 305 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 18 297 15.598 T 23-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 APE_1878 8945ddc232ef18457cab898c343c5fe8 305 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 20 295 1.5E-81 T 23-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 APE_1878 8945ddc232ef18457cab898c343c5fe8 305 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 72 94 - T 23-10-2018 IPR030470 UbiA prenyltransferase conserved site APE_1878 8945ddc232ef18457cab898c343c5fe8 305 Gene3D G3DSA:1.10.357.140 28 186 1.6E-16 T 23-10-2018 APE_1073 e827530472630c20589b2d870c919067 539 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 396 536 6.3E-22 T 23-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 APE_1073 e827530472630c20589b2d870c919067 539 Pfam PF04851 Type III restriction enzyme, res subunit 166 306 4.5E-21 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 APE_1073 e827530472630c20589b2d870c919067 539 SMART SM00490 431 511 1.2E-14 T 23-10-2018 IPR001650 Helicase, C-terminal APE_1073 e827530472630c20589b2d870c919067 539 Gene3D G3DSA:3.40.50.300 160 331 3.2E-41 T 23-10-2018 APE_1073 e827530472630c20589b2d870c919067 539 SMART SM00487 163 333 1.5E-24 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain APE_1073 e827530472630c20589b2d870c919067 539 SUPERFAMILY SSF52540 207 531 5.02E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2284a 93a9c149a9024dddd30ca3f9ebb51f41 78 SMART SM00746 6 44 7.4E-11 T 23-10-2018 IPR011017 TRASH domain APE_2284a 93a9c149a9024dddd30ca3f9ebb51f41 78 Pfam PF04945 YHS domain 5 50 4.0E-19 T 23-10-2018 IPR007029 YHS domain APE_2284a 93a9c149a9024dddd30ca3f9ebb51f41 78 SUPERFAMILY SSF47240 7 50 1.32E-10 T 23-10-2018 IPR009078 Ferritin-like superfamily APE_2284a 93a9c149a9024dddd30ca3f9ebb51f41 78 Gene3D G3DSA:1.10.620.20 3 68 4.2E-10 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 APE_0801.1 dc470776892aa53fff40ec86894b2019 267 Pfam PF01975 Survival protein SurE 5 183 2.1E-39 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 APE_0801.1 dc470776892aa53fff40ec86894b2019 267 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 264 23.911 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 APE_0801.1 dc470776892aa53fff40ec86894b2019 267 Gene3D G3DSA:3.40.1210.10 3 254 3.2E-43 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 APE_0801.1 dc470776892aa53fff40ec86894b2019 267 SUPERFAMILY SSF64167 3 261 1.57E-50 T 23-10-2018 APE_0620.1 df04ba859046ac0ef69704c8f574846e 1950 Pfam PF13620 Carboxypeptidase regulatory-like domain 1833 1905 2.6E-10 T 23-10-2018 APE_0620.1 df04ba859046ac0ef69704c8f574846e 1950 Gene3D G3DSA:2.60.40.1120 1830 1912 8.1E-8 T 23-10-2018 APE_0620.1 df04ba859046ac0ef69704c8f574846e 1950 SUPERFAMILY SSF49464 1833 1909 9.81E-10 T 23-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily APE_0620.1 df04ba859046ac0ef69704c8f574846e 1950 SUPERFAMILY SSF50998 81 601 2.75E-8 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily APE_1180 0aac5b10a8c08df7c89635147446f759 330 SUPERFAMILY SSF51735 1 323 2.9E-92 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_1180 0aac5b10a8c08df7c89635147446f759 330 Gene3D G3DSA:3.90.25.10 191 311 4.3E-116 T 23-10-2018 APE_1180 0aac5b10a8c08df7c89635147446f759 330 Gene3D G3DSA:3.40.50.720 2 303 4.3E-116 T 23-10-2018 APE_1180 0aac5b10a8c08df7c89635147446f759 330 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 9.5E-153 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 APE_1180 0aac5b10a8c08df7c89635147446f759 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 4.6E-77 T 23-10-2018 IPR016040 NAD(P)-binding domain APE_1399 7b24ccd354e75f34b58eda6aeb9f0855 333 SMART SM00382 38 251 2.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1399 7b24ccd354e75f34b58eda6aeb9f0855 333 SUPERFAMILY SSF52540 38 314 2.02E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1399 7b24ccd354e75f34b58eda6aeb9f0855 333 Pfam PF00005 ABC transporter 30 193 6.5E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_1399 7b24ccd354e75f34b58eda6aeb9f0855 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 328 2.6E-29 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1399 7b24ccd354e75f34b58eda6aeb9f0855 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 309 1.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 APE_1399 7b24ccd354e75f34b58eda6aeb9f0855 333 Gene3D G3DSA:3.40.50.300 7 333 2.1E-96 T 23-10-2018 APE_2256.1 d0aca9b1860cdaf4286f590c155fa0c7 306 PIRSF PIRSF014470 2 306 4.8E-141 T 23-10-2018 IPR016620 Uncharacterised conserved protein UCP014470 APE_2256.1 d0aca9b1860cdaf4286f590c155fa0c7 306 TIGRFAM TIGR02619 TIGR02619: putative CRISPR-associated protein, APE2256 family 77 226 5.4E-65 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 APE_2256.1 d0aca9b1860cdaf4286f590c155fa0c7 306 Pfam PF09651 CRISPR-associated protein (Cas_APE2256) 89 225 2.0E-37 T 23-10-2018 IPR013442 CRISPR-associated protein APE2256 APE_2256.1 d0aca9b1860cdaf4286f590c155fa0c7 306 Gene3D G3DSA:3.40.50.10770 67 229 3.3E-33 T 23-10-2018 APE_0236.1 bb3dea36278cb1bd968ff561abeeccea 249 SUPERFAMILY SSF53790 5 245 2.49E-62 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 APE_0236.1 bb3dea36278cb1bd968ff561abeeccea 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 216 1.2E-42 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 APE_0236.1 bb3dea36278cb1bd968ff561abeeccea 249 Gene3D G3DSA:3.40.1010.10 4 120 1.9E-34 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 APE_0236.1 bb3dea36278cb1bd968ff561abeeccea 249 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 85 118 - T 23-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APE_0236.1 bb3dea36278cb1bd968ff561abeeccea 249 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 6 242 2.0E-71 T 23-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 APE_0236.1 bb3dea36278cb1bd968ff561abeeccea 249 Gene3D G3DSA:3.30.950.10 121 249 1.2E-32 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 APE_0965.1 0ca91fa8ab8a77ed093f471e32d73476 287 SUPERFAMILY SSF103481 193 286 2.35E-7 T 23-10-2018 APE_0965.1 0ca91fa8ab8a77ed093f471e32d73476 287 Pfam PF00892 EamA-like transporter family 5 137 1.1E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_0965.1 0ca91fa8ab8a77ed093f471e32d73476 287 Pfam PF00892 EamA-like transporter family 154 286 1.9E-8 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 APE_0965.1 0ca91fa8ab8a77ed093f471e32d73476 287 SUPERFAMILY SSF103481 43 141 1.16E-8 T 23-10-2018 APE_1188 c744ca7631a1abef46ab95a7d9877ea4 383 SUPERFAMILY SSF53756 78 374 1.38E-22 T 23-10-2018 APE_1188 c744ca7631a1abef46ab95a7d9877ea4 383 Pfam PF00534 Glycosyl transferases group 1 199 346 1.7E-8 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 APE_1188 c744ca7631a1abef46ab95a7d9877ea4 383 Gene3D G3DSA:3.40.50.2000 44 192 2.8E-5 T 23-10-2018 APE_1188 c744ca7631a1abef46ab95a7d9877ea4 383 Gene3D G3DSA:3.40.50.2000 193 359 1.2E-14 T 23-10-2018 APE_0113 ba1e393729f4983e66fa53636a02ced2 409 Pfam PF00149 Calcineurin-like phosphoesterase 3 202 2.6E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 APE_0113 ba1e393729f4983e66fa53636a02ced2 409 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 2 400 20.474 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 APE_0113 ba1e393729f4983e66fa53636a02ced2 409 Gene3D G3DSA:3.60.21.10 3 251 1.7E-39 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like APE_0113 ba1e393729f4983e66fa53636a02ced2 409 SUPERFAMILY SSF56300 1 313 1.1E-43 T 23-10-2018 APE_0623.1 e07a32791fe81510c750178fd8ccc4e9 112 SUPERFAMILY SSF57783 2 90 2.95E-9 T 23-10-2018 APE_0623.1 e07a32791fe81510c750178fd8ccc4e9 112 Pfam PF05129 Transcription elongation factor Elf1 like 2 88 1.4E-17 T 23-10-2018 IPR007808 Transcription elongation factor 1 APE_1819 1604cd83cf7cf73a513f0f9fb433d5ae 363 SUPERFAMILY SSF55120 22 347 1.73E-41 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 APE_1819 1604cd83cf7cf73a513f0f9fb433d5ae 363 Gene3D G3DSA:3.30.2350.20 29 180 1.3E-11 T 23-10-2018 APE_1819 1604cd83cf7cf73a513f0f9fb433d5ae 363 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 37 172 2.2E-11 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 APE_2406.1 4c8a6a7b85918465301669479000d12e 226 Pfam PF00005 ABC transporter 7 131 6.5E-13 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 APE_2406.1 4c8a6a7b85918465301669479000d12e 226 Gene3D G3DSA:3.40.50.300 2 194 6.6E-38 T 23-10-2018 APE_2406.1 4c8a6a7b85918465301669479000d12e 226 SUPERFAMILY SSF52540 6 190 1.26E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2406.1 4c8a6a7b85918465301669479000d12e 226 SMART SM00382 15 184 2.1E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1887.1 a7528863d5e56612c2acb27fa4e685e9 429 SUPERFAMILY SSF53743 26 299 1.27E-38 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 APE_2023 aeb055beb7554719b392772063b68e59 411 Pfam PF00266 Aminotransferase class-V 21 399 4.4E-131 T 23-10-2018 IPR000192 Aminotransferase class V domain APE_2023 aeb055beb7554719b392772063b68e59 411 Gene3D G3DSA:3.90.1150.10 12 400 2.6E-131 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 APE_2023 aeb055beb7554719b392772063b68e59 411 SUPERFAMILY SSF53383 12 407 4.39E-107 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase APE_2023 aeb055beb7554719b392772063b68e59 411 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 212 231 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site APE_2023 aeb055beb7554719b392772063b68e59 411 Gene3D G3DSA:3.40.640.10 39 300 2.6E-131 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 APE_1715.1 38b76b3c7b6fd439899f003f2d3df47e 297 Gene3D G3DSA:1.10.4200.10 37 292 4.8E-21 T 23-10-2018 APE_1715.1 38b76b3c7b6fd439899f003f2d3df47e 297 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 11 283 1.1E-37 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 APE_2522.1 f05ea8d107ac48ba255b24f432aafe44 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 276 3.4E-39 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_1333 1e69b27f8cd3bccccc0f1e0e9322b1fc 103 Gene3D G3DSA:3.30.70.100 1 101 1.6E-19 T 23-10-2018 APE_1333 1e69b27f8cd3bccccc0f1e0e9322b1fc 103 SUPERFAMILY SSF54909 13 81 3.47E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel APE_1333 1e69b27f8cd3bccccc0f1e0e9322b1fc 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 5 78 8.0E-17 T 23-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain APE_0431 e7d61430694aa50e68d72ee89e9b4ae3 187 SUPERFAMILY SSF52540 19 159 1.15E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0431 e7d61430694aa50e68d72ee89e9b4ae3 187 Gene3D G3DSA:3.40.50.300 8 116 1.1E-5 T 23-10-2018 APE_2277.1 bd3e2496319ca48f9dfcd2b39954f6a5 268 SUPERFAMILY SSF56317 2 266 8.89E-57 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APE_2277.1 bd3e2496319ca48f9dfcd2b39954f6a5 268 Gene3D G3DSA:3.60.110.10 1 266 8.9E-62 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily APE_2277.1 bd3e2496319ca48f9dfcd2b39954f6a5 268 Pfam PF00795 Carbon-nitrogen hydrolase 3 248 1.4E-35 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 APE_0715.1 0eb3a31dae82902bb0af45c80716c45d 503 Pfam PF02386 Cation transport protein 318 498 3.8E-25 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 APE_0715.1 0eb3a31dae82902bb0af45c80716c45d 503 Pfam PF02386 Cation transport protein 82 285 1.3E-21 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 APE_1009.1 cb205764ed863693561be22b983aa6f7 168 Pfam PF04027 Domain of unknown function (DUF371) 8 138 9.5E-47 T 23-10-2018 IPR007171 Protein of unknown function DUF371 APE_1009.1 cb205764ed863693561be22b983aa6f7 168 Gene3D G3DSA:2.60.120.630 4 145 4.8E-48 T 23-10-2018 IPR023131 Mth639-like domain superfamily APE_1106.1 e12453da4d8ed416f138143b30e14be3 344 Gene3D G3DSA:3.40.50.150 85 341 2.4E-42 T 23-10-2018 APE_1106.1 e12453da4d8ed416f138143b30e14be3 344 SUPERFAMILY SSF53335 84 339 2.04E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1106.1 e12453da4d8ed416f138143b30e14be3 344 Pfam PF02475 Met-10+ like-protein 85 281 1.9E-37 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 APE_2350.1 97af79659ffcfbe1fa6e2ffc91f9dedf 207 Gene3D G3DSA:3.40.50.850 6 207 4.1E-55 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 APE_2350.1 97af79659ffcfbe1fa6e2ffc91f9dedf 207 Pfam PF00857 Isochorismatase family 26 187 8.1E-43 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 APE_2350.1 97af79659ffcfbe1fa6e2ffc91f9dedf 207 SUPERFAMILY SSF52499 14 199 1.1E-58 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 APE_1814.1 06f45193ff70c81d29a2a4c75475dc90 301 SUPERFAMILY SSF47240 14 131 2.64E-15 T 23-10-2018 IPR009078 Ferritin-like superfamily APE_1814.1 06f45193ff70c81d29a2a4c75475dc90 301 Pfam PF02915 Rubrerythrin 15 128 8.3E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 APE_1814.1 06f45193ff70c81d29a2a4c75475dc90 301 Gene3D G3DSA:1.20.1260.10 14 135 1.9E-7 T 23-10-2018 IPR012347 Ferritin-like APE_2592a a8bb397c1a1bca8a2f02421d235b9e88 65 SUPERFAMILY SSF64307 16 60 1.83E-5 T 23-10-2018 IPR036868 TusA-like domain superfamily APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 PRINTS PR00095 Anthranilate synthase component I signature 379 393 3.7E-15 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 PRINTS PR00095 Anthranilate synthase component I signature 271 284 3.7E-15 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 PRINTS PR00095 Anthranilate synthase component I signature 285 298 3.7E-15 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 PRINTS PR00095 Anthranilate synthase component I signature 365 379 3.7E-15 T 23-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 Pfam PF00425 chorismate binding enzyme 170 424 4.6E-88 T 23-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 SUPERFAMILY SSF56322 34 434 7.2E-118 T 23-10-2018 IPR005801 ADC synthase GO:0009058 APE_2553.1 a9a94633466e5b2b80828c35f721a435 438 Gene3D G3DSA:3.60.120.10 22 436 9.4E-121 T 23-10-2018 IPR005801 ADC synthase GO:0009058 APE_1568.1 88f48023bbaf3df2c222856d7ad723c4 110 Gene3D G3DSA:3.40.1260.10 2 109 2.8E-13 T 23-10-2018 IPR027396 DsrEFH-like APE_1568.1 88f48023bbaf3df2c222856d7ad723c4 110 SUPERFAMILY SSF75169 3 110 6.47E-7 T 23-10-2018 IPR027396 DsrEFH-like APE_1898 13a489a7e4cdfadd148746caaf180791 245 Gene3D G3DSA:3.40.50.300 11 243 2.1E-37 T 23-10-2018 APE_1898 13a489a7e4cdfadd148746caaf180791 245 SMART SM00382 33 198 0.0036 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_1898 13a489a7e4cdfadd148746caaf180791 245 SUPERFAMILY SSF52540 11 231 1.36E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1898 13a489a7e4cdfadd148746caaf180791 245 Pfam PF06745 KaiC 16 237 1.6E-14 T 23-10-2018 IPR014774 KaiC-like domain APE_0676 9a37ca585e3e5ffd0176afb3f59549c0 274 SUPERFAMILY SSF51621 5 263 5.5E-97 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APE_0676 9a37ca585e3e5ffd0176afb3f59549c0 274 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 264 9.0E-91 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APE_0676 9a37ca585e3e5ffd0176afb3f59549c0 274 Gene3D G3DSA:3.20.20.60 4 272 7.5E-107 T 23-10-2018 APE_0676 9a37ca585e3e5ffd0176afb3f59549c0 274 PIRSF PIRSF000388 2 267 1.9E-101 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APE_0676 9a37ca585e3e5ffd0176afb3f59549c0 274 Pfam PF02548 Ketopantoate hydroxymethyltransferase 5 259 7.3E-104 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APE_0676 9a37ca585e3e5ffd0176afb3f59549c0 274 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 6 264 40.178 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 SUPERFAMILY SSF51971 13 267 8.83E-52 T 23-10-2018 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 Gene3D G3DSA:3.50.50.60 265 336 2.7E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0935 ffd35b0497d96a3f727c051a1966c512 337 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 1.0E-17 T 23-10-2018 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 1.0E-17 T 23-10-2018 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 PRINTS PR00419 Adrenodoxin reductase family signature 81 91 1.0E-17 T 23-10-2018 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 PRINTS PR00419 Adrenodoxin reductase family signature 155 169 1.0E-17 T 23-10-2018 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 Gene3D G3DSA:3.50.50.60 5 123 4.5E-14 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_0935 ffd35b0497d96a3f727c051a1966c512 337 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 322 6.6E-23 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 APE_0935 ffd35b0497d96a3f727c051a1966c512 337 Gene3D G3DSA:3.50.50.60 124 264 1.9E-22 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1186.1 400c06b56b93394b872d128dae64412f 429 Pfam PF00534 Glycosyl transferases group 1 228 349 3.7E-7 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 APE_1186.1 400c06b56b93394b872d128dae64412f 429 Gene3D G3DSA:3.40.50.2000 224 403 2.1E-11 T 23-10-2018 APE_1186.1 400c06b56b93394b872d128dae64412f 429 SUPERFAMILY SSF53756 29 348 2.67E-13 T 23-10-2018 APE_0506 43ce1268326e873507d8e3bef0daaab6 218 Pfam PF04493 Endonuclease V 1 171 5.4E-51 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 APE_0506 43ce1268326e873507d8e3bef0daaab6 218 Gene3D G3DSA:3.30.2170.10 1 191 1.1E-53 T 23-10-2018 APE_0506 43ce1268326e873507d8e3bef0daaab6 218 Hamap MF_00801 Endonuclease V [nfi]. 1 181 26.666 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 APE_2616a 6d3fc656deebd42e82e0b634c2595f2b 64 Gene3D G3DSA:4.10.1150.10 1 62 8.8E-8 T 23-10-2018 IPR024069 AF2212-like domain superfamily APE_2616a 6d3fc656deebd42e82e0b634c2595f2b 64 Pfam PF01954 Protein of unknown function DUF104 2 61 5.0E-16 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_2616a 6d3fc656deebd42e82e0b634c2595f2b 64 SUPERFAMILY SSF141694 2 62 7.59E-11 T 23-10-2018 APE_1257 4349b9041c0eb0d7222b8d2172358865 439 Pfam PF12698 ABC-2 family transporter protein 45 401 9.7E-13 T 23-10-2018 APE_0222.1 0a3d82c1e83009a80f4e86aaabda64a0 308 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 10 294 48.083 T 23-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 APE_0222.1 0a3d82c1e83009a80f4e86aaabda64a0 308 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 14 293 4.3E-137 T 23-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 APE_0222.1 0a3d82c1e83009a80f4e86aaabda64a0 308 SUPERFAMILY SSF51621 11 300 1.12E-99 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 APE_0222.1 0a3d82c1e83009a80f4e86aaabda64a0 308 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 256 1.4E-53 T 23-10-2018 APE_0222.1 0a3d82c1e83009a80f4e86aaabda64a0 308 ProSitePatterns PS00161 Isocitrate lyase signature. 125 130 - T 23-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 APE_0222.1 0a3d82c1e83009a80f4e86aaabda64a0 308 Gene3D G3DSA:3.20.20.60 9 297 4.8E-107 T 23-10-2018 APE_1952.1 cd82c54fb2fcc0d360b6237b4973c722 463 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 7 320 1.7E-84 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 APE_1952.1 cd82c54fb2fcc0d360b6237b4973c722 463 Gene3D G3DSA:3.50.50.60 3 460 1.8E-129 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1952.1 cd82c54fb2fcc0d360b6237b4973c722 463 SUPERFAMILY SSF51905 6 327 5.13E-28 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1244.1 46f978c0e25906d9f2e88f6d8f3354ca 583 Gene3D G3DSA:3.40.50.1820 47 333 2.2E-25 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_1244.1 46f978c0e25906d9f2e88f6d8f3354ca 583 SUPERFAMILY SSF53474 71 323 3.98E-22 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold APE_1244.1 46f978c0e25906d9f2e88f6d8f3354ca 583 Pfam PF12146 Serine aminopeptidase, S33 102 220 3.4E-9 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 APE_0588.1 04e5d0c26c9ea35aab981c988dc1f51a 901 Gene3D G3DSA:1.50.10.10 516 639 2.1E-5 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 APE_0588.1 04e5d0c26c9ea35aab981c988dc1f51a 901 SUPERFAMILY SSF48208 518 716 4.63E-9 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 APE_2333.1 9c59886cf9a134c0f32d13f50a67e8c7 213 Gene3D G3DSA:3.40.1350.10 7 108 2.2E-6 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APE_2333.1 9c59886cf9a134c0f32d13f50a67e8c7 213 Pfam PF02021 Uncharacterised protein family UPF0102 11 60 2.6E-5 T 23-10-2018 IPR003509 Uncharacterised protein family UPF0102 APE_2333.1 9c59886cf9a134c0f32d13f50a67e8c7 213 SUPERFAMILY SSF52980 7 107 1.01E-14 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 APE_0792.1 c9a364cf45e33f33aba4e680c9bec8cc 236 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 130 202 2.0E-15 T 23-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0792.1 c9a364cf45e33f33aba4e680c9bec8cc 236 Gene3D G3DSA:2.60.40.2600 101 226 2.1E-35 T 23-10-2018 APE_0792.1 c9a364cf45e33f33aba4e680c9bec8cc 236 SUPERFAMILY SSF49503 102 218 1.14E-34 T 23-10-2018 IPR008972 Cupredoxin APE_0792.1 c9a364cf45e33f33aba4e680c9bec8cc 236 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 151 201 - T 23-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0792.1 c9a364cf45e33f33aba4e680c9bec8cc 236 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 7 218 6.8E-72 T 23-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_0516.1 786509b99e40e6f5d631064acdd7c389 174 Gene3D G3DSA:2.30.130.10 105 172 7.6E-13 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 APE_0516.1 786509b99e40e6f5d631064acdd7c389 174 Pfam PF03657 Uncharacterised protein family (UPF0113) 11 172 1.2E-70 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 APE_2470 d18d8cbdd867c37daa31f72cbdf0a422 103 Gene3D G3DSA:1.10.10.10 29 101 5.6E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_2470 d18d8cbdd867c37daa31f72cbdf0a422 103 Pfam PF03297 S25 ribosomal protein 7 89 6.6E-11 T 23-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_2470 d18d8cbdd867c37daa31f72cbdf0a422 103 SUPERFAMILY SSF46785 43 90 1.41E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0125.1 342b8309c8a3867e94a2b53036d8d56d 483 Pfam PF13559 Domain of unknown function (DUF4129) 402 471 4.4E-14 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 APE_1336.1 d8d43981c7e758a16f164a700592d797 549 Gene3D G3DSA:3.50.50.60 182 331 4.6E-15 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1336.1 d8d43981c7e758a16f164a700592d797 549 SUPERFAMILY SSF51905 7 309 3.27E-43 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1336.1 d8d43981c7e758a16f164a700592d797 549 Gene3D G3DSA:3.50.50.60 6 78 7.2E-14 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily APE_1336.1 d8d43981c7e758a16f164a700592d797 549 Pfam PF01593 Flavin containing amine oxidoreductase 18 499 9.8E-18 T 23-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 APE_2180.1 8ddd289de33b2c71769716e08de6b37e 250 SUPERFAMILY SSF117396 2 244 4.32E-43 T 23-10-2018 IPR036520 UPF0759 superfamily APE_2180.1 8ddd289de33b2c71769716e08de6b37e 250 Pfam PF01904 Protein of unknown function DUF72 19 241 5.0E-31 T 23-10-2018 IPR002763 Protein of unknown function DUF72 APE_2180.1 8ddd289de33b2c71769716e08de6b37e 250 Gene3D G3DSA:3.20.20.410 2 247 1.9E-35 T 23-10-2018 IPR036520 UPF0759 superfamily APE_2253.1 37c7c33e8ab00f4e42a9eeaeb188a4a0 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 297 2.9E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_2253.1 37c7c33e8ab00f4e42a9eeaeb188a4a0 314 Gene3D G3DSA:1.10.3720.10 7 299 1.8E-36 T 23-10-2018 IPR035906 MetI-like superfamily APE_2253.1 37c7c33e8ab00f4e42a9eeaeb188a4a0 314 SUPERFAMILY SSF161098 10 304 4.97E-36 T 23-10-2018 IPR035906 MetI-like superfamily APE_2208.1 71b93a47ae9e1c7e28342cb7f26f9508 580 Pfam PF00437 Type II/IV secretion system protein 188 438 8.3E-47 T 23-10-2018 IPR001482 Type II/IV secretion system protein APE_2208.1 71b93a47ae9e1c7e28342cb7f26f9508 580 SUPERFAMILY SSF52540 172 553 3.78E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2208.1 71b93a47ae9e1c7e28342cb7f26f9508 580 Gene3D G3DSA:3.40.50.300 287 575 3.1E-89 T 23-10-2018 APE_2208.1 71b93a47ae9e1c7e28342cb7f26f9508 580 Gene3D G3DSA:3.30.450.380 47 285 1.9E-72 T 23-10-2018 APE_1751 0b707f220b0cefd3239d6990c1bb82c2 150 SUPERFAMILY SSF55282 9 149 1.65E-41 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1751 0b707f220b0cefd3239d6990c1bb82c2 150 Pfam PF01877 RNA binding 9 122 1.1E-19 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 APE_1751 0b707f220b0cefd3239d6990c1bb82c2 150 Gene3D G3DSA:3.30.1440.10 7 143 3.8E-42 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1751 0b707f220b0cefd3239d6990c1bb82c2 150 Hamap MF_01112 UPF0201 protein . 8 141 27.794 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 Gene3D G3DSA:3.40.190.80 157 262 2.6E-18 T 23-10-2018 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 Gene3D G3DSA:3.30.540.10 2 141 3.5E-19 T 23-10-2018 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 Pfam PF00459 Inositol monophosphatase family 5 243 3.9E-39 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 3.6E-19 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 3.6E-19 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 3.6E-19 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 3.6E-19 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 3.6E-19 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 APE_1798.1 42e8ef4aa08c26f4d1bca520781a6289 267 SUPERFAMILY SSF56655 37 256 3.53E-38 T 23-10-2018 APE_1708 d9f217e288e65c01e72bcce3a95d05df 791 SUPERFAMILY SSF58104 430 713 1.1E-5 T 23-10-2018 APE_1825.1 4d4e1c2f93dc745256cba70951ea563a 376 PIRSF PIRSF016907 2 376 5.9E-150 T 23-10-2018 IPR011386 Putative ATP-NAD kinase APE_1825.1 4d4e1c2f93dc745256cba70951ea563a 376 Pfam PF01513 ATP-NAD kinase 6 375 6.8E-47 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 APE_1825.1 4d4e1c2f93dc745256cba70951ea563a 376 SUPERFAMILY SSF111331 102 184 2.62E-7 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily APE_1123.1 76d4badbb5c40d5942f2937ed5fe2448 372 Pfam PF07431 Protein of unknown function (DUF1512) 15 371 4.1E-144 T 23-10-2018 IPR009995 Protein of unknown function DUF1512 APE_1123.1 76d4badbb5c40d5942f2937ed5fe2448 372 PIRSF PIRSF016495 1 372 5.0E-161 T 23-10-2018 IPR009995 Protein of unknown function DUF1512 APE_1799a a25497d1771bea16875dda13f4d89814 79 Gene3D G3DSA:3.30.70.920 6 77 1.7E-20 T 23-10-2018 APE_1799a a25497d1771bea16875dda13f4d89814 79 Pfam PF01037 Lrp/AsnC ligand binding domain 9 78 1.6E-10 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain APE_1799a a25497d1771bea16875dda13f4d89814 79 SUPERFAMILY SSF54909 5 78 1.07E-11 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel APE_0591.1 e331fa0293f31ef8fd2b853965b15995 266 Gene3D G3DSA:3.90.226.10 2 259 6.9E-63 T 23-10-2018 APE_0591.1 e331fa0293f31ef8fd2b853965b15995 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 21 257 1.4E-40 T 23-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 APE_0591.1 e331fa0293f31ef8fd2b853965b15995 266 SUPERFAMILY SSF52096 4 259 9.67E-63 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily APE_1470.1 57185ece25ccbb28a61a5fe9fb1df9b2 269 PIRSF PIRSF006293 2 248 1.9E-44 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APE_1470.1 57185ece25ccbb28a61a5fe9fb1df9b2 269 Gene3D G3DSA:3.40.50.620 4 244 1.3E-52 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold APE_1470.1 57185ece25ccbb28a61a5fe9fb1df9b2 269 SUPERFAMILY SSF52402 5 244 4.97E-35 T 23-10-2018 APE_1470.1 57185ece25ccbb28a61a5fe9fb1df9b2 269 Pfam PF06508 Queuosine biosynthesis protein QueC 5 236 2.8E-39 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APE_1470.1 57185ece25ccbb28a61a5fe9fb1df9b2 269 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 242 38.434 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 APE_1885 ab49d8e3dd93373d8a2728a4c85260fa 275 SUPERFAMILY SSF53167 12 273 5.76E-94 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APE_1885 ab49d8e3dd93373d8a2728a4c85260fa 275 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 13 253 9.1E-111 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 APE_1885 ab49d8e3dd93373d8a2728a4c85260fa 275 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 12 275 44.732 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 APE_1885 ab49d8e3dd93373d8a2728a4c85260fa 275 Pfam PF01048 Phosphorylase superfamily 14 252 2.3E-48 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 APE_1885 ab49d8e3dd93373d8a2728a4c85260fa 275 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 60 100 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 APE_1885 ab49d8e3dd93373d8a2728a4c85260fa 275 Gene3D G3DSA:3.40.50.1580 1 275 5.4E-106 T 23-10-2018 APE_1721 db8185bf0c84bea35f7e55224f43c6c4 254 SUPERFAMILY SSF52833 78 229 6.72E-14 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1721 db8185bf0c84bea35f7e55224f43c6c4 254 Gene3D G3DSA:3.40.30.10 73 242 3.0E-15 T 23-10-2018 APE_0537a 9e78cea7832ece76906e7926778bf043 91 Pfam PF01294 Ribosomal protein L13e 34 84 5.8E-12 T 23-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0537a 9e78cea7832ece76906e7926778bf043 91 ProSitePatterns PS01104 Ribosomal protein L13e signature. 35 49 - T 23-10-2018 IPR018256 Ribosomal protein L13e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0537a 9e78cea7832ece76906e7926778bf043 91 Hamap MF_00499 50S ribosomal protein L13e [rpl13e]. 12 89 22.738 T 23-10-2018 IPR001380 Ribosomal protein L13e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1529.1 6a850b2f4ed5495f456be99d47382cae 108 Pfam PF04930 FUN14 family 17 105 1.1E-14 T 23-10-2018 IPR007014 FUN14 APE_1235 00803e201aa43340b024dbd380cdbb07 347 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 3 287 5.4E-110 T 23-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern APE_1235 00803e201aa43340b024dbd380cdbb07 347 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 265 3.1E-39 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR APE_1235 00803e201aa43340b024dbd380cdbb07 347 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 281 4.6E-70 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR APE_1503.1 b83b5740159500a4ba29b4e30525a64c 164 Gene3D G3DSA:3.40.50.150 6 159 4.3E-49 T 23-10-2018 APE_1503.1 b83b5740159500a4ba29b4e30525a64c 164 Pfam PF13649 Methyltransferase domain 36 122 7.8E-10 T 23-10-2018 APE_1503.1 b83b5740159500a4ba29b4e30525a64c 164 SUPERFAMILY SSF53335 11 135 1.86E-33 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1764.1 0b037a11850e6e1e0caeca90bf74ea11 332 Gene3D G3DSA:1.10.600.10 4 332 7.7E-98 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily APE_1764.1 0b037a11850e6e1e0caeca90bf74ea11 332 SUPERFAMILY SSF48576 19 331 1.1E-88 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily APE_1764.1 0b037a11850e6e1e0caeca90bf74ea11 332 Pfam PF00348 Polyprenyl synthetase 31 280 2.6E-67 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 APE_1764.1 0b037a11850e6e1e0caeca90bf74ea11 332 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site APE_0531.1 34a8cd57656663563ccd5fc7a54f57c4 300 SUPERFAMILY SSF53807 37 290 5.89E-27 T 23-10-2018 APE_0531.1 34a8cd57656663563ccd5fc7a54f57c4 300 Pfam PF01297 Zinc-uptake complex component A periplasmic 47 248 2.6E-10 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 APE_0531.1 34a8cd57656663563ccd5fc7a54f57c4 300 Gene3D G3DSA:3.40.50.1980 44 189 2.3E-10 T 23-10-2018 APE_2199a 373fddd1fafb5efb7f04c1550aca4a97 50 Pfam PF04758 Ribosomal protein S30 3 47 4.2E-12 T 23-10-2018 IPR006846 Ribosomal protein S30 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0640 23bb6246bf533abaef4ad3974900b6e7 257 SUPERFAMILY SSF53167 5 201 1.91E-15 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 APE_0640 23bb6246bf533abaef4ad3974900b6e7 257 Gene3D G3DSA:3.40.50.1580 38 253 5.4E-8 T 23-10-2018 APE_2235 59f6dd2ecd92b2a745ac7872a07ed376 216 Gene3D G3DSA:3.40.50.300 4 186 1.4E-8 T 23-10-2018 APE_2235 59f6dd2ecd92b2a745ac7872a07ed376 216 SUPERFAMILY SSF52540 6 184 1.36E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1797 366c3835c32c9b82a66b1e26528e7974 229 Gene3D G3DSA:3.50.40.10 62 221 5.4E-10 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 APE_1797 366c3835c32c9b82a66b1e26528e7974 229 Pfam PF03483 B3/4 domain 66 216 3.4E-30 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 APE_1797 366c3835c32c9b82a66b1e26528e7974 229 SUPERFAMILY SSF56037 53 223 3.92E-38 T 23-10-2018 APE_1797 366c3835c32c9b82a66b1e26528e7974 229 SMART SM00873 65 217 2.2E-27 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 APE_1442 c59e4ed4de8b1f0be4ee71cb32f9b847 239 Pfam PF04254 Protein of unknown function (DUF432) 60 182 1.4E-27 T 23-10-2018 IPR007366 Protein of unknown function DUF432 APE_0948.1 520eb188241ac1990a94a47a88f784dd 119 PIRSF PIRSF000178 1 80 1.5E-6 T 23-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0948.1 520eb188241ac1990a94a47a88f784dd 119 PIRSF PIRSF000178 92 118 240.0 T 23-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0948.1 520eb188241ac1990a94a47a88f784dd 119 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 1 111 6.3E-12 T 23-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0948.1 520eb188241ac1990a94a47a88f784dd 119 Gene3D G3DSA:1.20.1300.10 1 119 2.4E-7 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0948.1 520eb188241ac1990a94a47a88f784dd 119 SUPERFAMILY SSF81343 1 116 1.79E-12 T 23-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 APE_0116.1 d0010344e4865f11fa63a31afd7eadd6 185 SMART SM01022 1 99 2.4E-22 T 23-10-2018 IPR007374 ASCH domain APE_0116.1 d0010344e4865f11fa63a31afd7eadd6 185 SUPERFAMILY SSF88697 3 96 1.66E-16 T 23-10-2018 IPR015947 PUA-like superfamily APE_0116.1 d0010344e4865f11fa63a31afd7eadd6 185 Pfam PF04266 ASCH domain 3 97 6.2E-15 T 23-10-2018 IPR007374 ASCH domain APE_1545.1 6ffba9d56a1b3709928af19bc833e788 198 Pfam PF06195 Protein of unknown function (DUF996) 31 166 6.8E-34 T 23-10-2018 IPR010397 Protein of unknown function DUF996 APE_1545.1 6ffba9d56a1b3709928af19bc833e788 198 PIRSF PIRSF019678 6 184 7.4E-63 T 23-10-2018 IPR010397 Protein of unknown function DUF996 APE_0297 2dab13b25d6867e50118373eb683ed6d 139 SUPERFAMILY SSF46785 68 137 1.2E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1007a 81902532d0589468b269e1685aa60cf2 90 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 33 8.9E-9 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 APE_1007a 81902532d0589468b269e1685aa60cf2 90 SUPERFAMILY SSF57783 1 38 3.57E-5 T 23-10-2018 APE_1007a 81902532d0589468b269e1685aa60cf2 90 SMART SM00661 2 55 1.9E-19 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 APE_0264.1 4fa465efcbc2fa57698a35008981d23d 210 Pfam PF13643 Domain of unknown function (DUF4145) 52 156 7.1E-5 T 23-10-2018 IPR025285 Domain of unknown function DUF4145 APE_2258 57ed4d1fd424c2a30ce4a76dbf2fe0e4 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 339 8.8E-42 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_2348 bab315a238e601791ac620f6a2661d21 244 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 12 220 4.2E-27 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_2348 bab315a238e601791ac620f6a2661d21 244 SMART SM00934 12 222 6.8E-36 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_2348 bab315a238e601791ac620f6a2661d21 244 SUPERFAMILY SSF51366 9 225 7.54E-40 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 APE_2348 bab315a238e601791ac620f6a2661d21 244 Gene3D G3DSA:3.20.20.70 10 234 1.5E-47 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_2348 bab315a238e601791ac620f6a2661d21 244 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 13 232 36.675 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 42 66 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 SUPERFAMILY SSF53613 9 291 8.26E-77 T 23-10-2018 IPR029056 Ribokinase-like APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 Pfam PF00294 pfkB family carbohydrate kinase 9 292 1.6E-60 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 PRINTS PR00990 Ribokinase signature 218 229 5.4E-10 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 PRINTS PR00990 Ribokinase signature 179 194 5.4E-10 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 PRINTS PR00990 Ribokinase signature 10 31 5.4E-10 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 PRINTS PR00990 Ribokinase signature 37 56 5.4E-10 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 APE_0012 08f9994f5d2df4844e3a0a39acf6e6e8 310 Gene3D G3DSA:3.40.1190.20 4 306 1.1E-82 T 23-10-2018 IPR029056 Ribokinase-like APE_0197.1 43aad77e307003d86b1148506ba56f36 255 Gene3D G3DSA:1.10.260.40 29 108 1.9E-8 T 23-10-2018 APE_0197.1 43aad77e307003d86b1148506ba56f36 255 SUPERFAMILY SSF47413 34 85 2.95E-10 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 APE_0197.1 43aad77e307003d86b1148506ba56f36 255 SMART SM00530 39 93 2.1E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 APE_0197.1 43aad77e307003d86b1148506ba56f36 255 PIRSF PIRSF037724 8 247 3.0E-95 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted APE_0197.1 43aad77e307003d86b1148506ba56f36 255 Pfam PF13560 Helix-turn-helix domain 35 85 8.8E-7 T 23-10-2018 APE_0685 a4668e89465d5f46c8b3a1287e05e2c1 170 Gene3D G3DSA:3.40.1170.20 3 80 1.3E-49 T 23-10-2018 APE_0685 a4668e89465d5f46c8b3a1287e05e2c1 170 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 87 160 1.1E-4 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 APE_0685 a4668e89465d5f46c8b3a1287e05e2c1 170 Gene3D G3DSA:3.40.1350.10 81 170 3.0E-42 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APE_0685 a4668e89465d5f46c8b3a1287e05e2c1 170 SUPERFAMILY SSF53032 86 166 4.71E-10 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 APE_0122.1 a280eebd1477a574b330a39caffb752d 177 Pfam PF01230 HIT domain 45 136 1.1E-13 T 23-10-2018 IPR001310 Histidine triad (HIT) protein APE_0122.1 a280eebd1477a574b330a39caffb752d 177 Gene3D G3DSA:3.30.428.10 2 175 2.7E-54 T 23-10-2018 IPR036265 HIT-like superfamily APE_0122.1 a280eebd1477a574b330a39caffb752d 177 SUPERFAMILY SSF54197 12 164 2.78E-42 T 23-10-2018 IPR036265 HIT-like superfamily APE_0727 dd0ea823b803e3d567472d09dcc13e0b 284 Pfam PF16317 Glycosyl hydrolase family 99 2 109 1.0E-8 T 23-10-2018 IPR026071 Glycosyl hydrolase family 99 GO:0016798 APE_0727 dd0ea823b803e3d567472d09dcc13e0b 284 Gene3D G3DSA:3.20.20.80 131 254 3.7E-10 T 23-10-2018 APE_0727 dd0ea823b803e3d567472d09dcc13e0b 284 Gene3D G3DSA:3.20.20.80 1 120 2.6E-24 T 23-10-2018 APE_1013.1 6598e974d0679ff116583b1ea1d51104 170 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 27 3.4E-4 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal APE_1013.1 6598e974d0679ff116583b1ea1d51104 170 Pfam PF07790 Archaeal Type IV pilin, N-terminal 5 90 3.8E-7 T 23-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal APE_0372.1 146d74925f0806af12a84663a34f1262 291 Pfam PF07728 AAA domain (dynein-related subfamily) 43 182 5.9E-19 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 APE_0372.1 146d74925f0806af12a84663a34f1262 291 Gene3D G3DSA:1.10.8.80 216 288 4.0E-5 T 23-10-2018 APE_0372.1 146d74925f0806af12a84663a34f1262 291 SUPERFAMILY SSF52540 28 276 6.0E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0372.1 146d74925f0806af12a84663a34f1262 291 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 119 137 9.7E-7 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 APE_0372.1 146d74925f0806af12a84663a34f1262 291 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 44 62 9.7E-7 T 23-10-2018 IPR001270 ClpA/B family GO:0005524 APE_0372.1 146d74925f0806af12a84663a34f1262 291 Gene3D G3DSA:3.40.50.300 16 215 6.6E-28 T 23-10-2018 APE_0372.1 146d74925f0806af12a84663a34f1262 291 SMART SM00382 40 189 2.3E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0243 6d52068108cd583ab0571d8e04b145aa 148 Gene3D G3DSA:3.40.30.10 27 147 2.2E-9 T 23-10-2018 APE_0243 6d52068108cd583ab0571d8e04b145aa 148 SUPERFAMILY SSF52833 27 142 1.57E-13 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1914.1 30eb9eead3efef669bae88ebce6382dc 394 Gene3D G3DSA:1.20.1250.20 9 385 1.8E-34 T 23-10-2018 APE_1914.1 30eb9eead3efef669bae88ebce6382dc 394 SUPERFAMILY SSF103473 12 385 4.58E-36 T 23-10-2018 IPR036259 MFS transporter superfamily APE_1914.1 30eb9eead3efef669bae88ebce6382dc 394 Pfam PF07690 Major Facilitator Superfamily 14 325 2.5E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_1914.1 30eb9eead3efef669bae88ebce6382dc 394 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 APE_1182 20e5f859ff7a20e5d26ee49aabf3bc2c 522 Gene3D G3DSA:3.40.720.10 1 274 2.6E-41 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APE_1182 20e5f859ff7a20e5d26ee49aabf3bc2c 522 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 3 439 1.5E-68 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 APE_1182 20e5f859ff7a20e5d26ee49aabf3bc2c 522 SUPERFAMILY SSF53649 2 472 4.22E-37 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 APE_1182 20e5f859ff7a20e5d26ee49aabf3bc2c 522 Gene3D G3DSA:3.40.720.10 429 506 1.1E-5 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 APE_0896.1 b453de454194769f4ca430ee17384089 270 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 26 2.3E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal APE_1195.1 111679e8ab424c71c6dbd4fb094b6c62 183 Pfam PF01583 Adenylylsulphate kinase 9 165 4.4E-59 T 23-10-2018 APE_1195.1 111679e8ab424c71c6dbd4fb094b6c62 183 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 8 177 1.9E-60 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APE_1195.1 111679e8ab424c71c6dbd4fb094b6c62 183 SUPERFAMILY SSF52540 7 179 3.71E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1195.1 111679e8ab424c71c6dbd4fb094b6c62 183 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 8 182 38.026 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 APE_1195.1 111679e8ab424c71c6dbd4fb094b6c62 183 Gene3D G3DSA:3.40.50.300 1 183 4.5E-67 T 23-10-2018 APE_1996.1 48dbb9b1dd9dbe03ed20d4c06555ae31 255 SUPERFAMILY SSF46785 36 98 2.64E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1699 b1f173f8d35b057b8f380c6f4d5236fe 167 Gene3D G3DSA:3.30.1460.10 7 152 7.2E-17 T 23-10-2018 APE_1699 b1f173f8d35b057b8f380c6f4d5236fe 167 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 10 148 1.7E-34 T 23-10-2018 IPR018747 Protein of unknown function DUF2299 APE_2206.1 d02b516a6a2bcd61a5f7689283b6e8f7 284 Pfam PF00482 Type II secretion system (T2SS), protein F 75 201 3.4E-14 T 23-10-2018 IPR018076 Type II secretion system F domain APE_0798 7df2b106ceceb76c75286151e204f05c 197 Pfam PF04191 Phospholipid methyltransferase 105 160 3.7E-7 T 23-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 APE_0798 7df2b106ceceb76c75286151e204f05c 197 Gene3D G3DSA:1.20.120.1630 92 182 3.6E-11 T 23-10-2018 APE_2225.1 87fed8ec1e0ba816889b55ea6b6b094a 147 SUPERFAMILY SSF55961 3 145 6.21E-40 T 23-10-2018 APE_2225.1 87fed8ec1e0ba816889b55ea6b6b094a 147 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 7 145 1.4E-46 T 23-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G APE_2225.1 87fed8ec1e0ba816889b55ea6b6b094a 147 Gene3D G3DSA:3.30.530.20 1 147 1.5E-42 T 23-10-2018 IPR023393 START-like domain superfamily APE_0562.1 d9225b31979b8be752b6733e494cc109 268 SUPERFAMILY SSF51735 4 157 3.43E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0562.1 d9225b31979b8be752b6733e494cc109 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 93 4.9E-11 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal APE_0562.1 d9225b31979b8be752b6733e494cc109 268 Gene3D G3DSA:3.40.50.720 2 166 6.4E-24 T 23-10-2018 APE_1526.1 b9d761a7d9c06db6fc2924ee199d0e6b 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 30 92 8.2E-10 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APE_1526.1 b9d761a7d9c06db6fc2924ee199d0e6b 194 Gene3D G3DSA:1.20.120.1760 9 194 2.0E-38 T 23-10-2018 APE_1526.1 b9d761a7d9c06db6fc2924ee199d0e6b 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 70 92 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 APE_0211.1 0bed439323034f06e37d8707903cb9d7 278 Gene3D G3DSA:3.40.1190.20 4 263 5.9E-31 T 23-10-2018 IPR029056 Ribokinase-like APE_0211.1 0bed439323034f06e37d8707903cb9d7 278 SUPERFAMILY SSF53613 5 249 1.57E-19 T 23-10-2018 IPR029056 Ribokinase-like APE_1810 a40bf15ba0e4108b824f358fe36ddb45 558 Pfam PF09818 Predicted ATPase of the ABC class 6 432 2.5E-151 T 23-10-2018 IPR019195 ABC transporter, ATPase, putative APE_2484.1 3d3f390cf8682b19ac05a802685bfacc 155 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 76 1.1E-11 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APE_2484.1 3d3f390cf8682b19ac05a802685bfacc 155 SMART SM00855 3 110 0.0021 T 23-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 APE_2484.1 3d3f390cf8682b19ac05a802685bfacc 155 Gene3D G3DSA:3.40.50.1240 4 154 4.1E-28 T 23-10-2018 IPR029033 Histidine phosphatase superfamily APE_2484.1 3d3f390cf8682b19ac05a802685bfacc 155 SUPERFAMILY SSF53254 2 131 8.9E-19 T 23-10-2018 IPR029033 Histidine phosphatase superfamily APE_0179a 63629f4646230397c068ab7a107dc4f9 67 ProDom PD010361 RIBOSOMAL RIBONUCLEOPROTEIN L38 60S L38 L38E FAMILY STRAIN MULTIGENE NRRL 1 56 0.003 T 23-10-2018 IPR002675 Ribosomal protein L38e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0179a 63629f4646230397c068ab7a107dc4f9 67 Gene3D G3DSA:3.30.720.90 1 65 1.1E-9 T 23-10-2018 IPR038464 Ribosomal protein L38e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0179a 63629f4646230397c068ab7a107dc4f9 67 Pfam PF01781 Ribosomal L38e protein family 4 56 7.2E-9 T 23-10-2018 IPR002675 Ribosomal protein L38e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1614 2a59236b66d081964793964159e2c1ed 160 SUPERFAMILY SSF117916 62 148 2.19E-6 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APE_0051 02a6707ca7ee5ee766d9743f44b88d9f 201 Gene3D G3DSA:1.20.58.220 6 201 1.2E-29 T 23-10-2018 IPR038078 PhoU-like domain superfamily APE_0051 02a6707ca7ee5ee766d9743f44b88d9f 201 Pfam PF01895 PhoU domain 17 102 8.8E-10 T 23-10-2018 IPR026022 PhoU domain APE_0051 02a6707ca7ee5ee766d9743f44b88d9f 201 Pfam PF01895 PhoU domain 120 199 7.3E-16 T 23-10-2018 IPR026022 PhoU domain APE_0051 02a6707ca7ee5ee766d9743f44b88d9f 201 SUPERFAMILY SSF109755 7 199 1.36E-30 T 23-10-2018 APE_1558 861abd18b512fb0266d92cb5b901c267 279 Pfam PF14338 Mrr N-terminal domain 211 278 7.9E-10 T 23-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain APE_1585 e74ceb8d47aa4f7736eac26e42e94f13 146 SUPERFAMILY SSF54631 28 131 1.36E-6 T 23-10-2018 APE_1001.1 092ce1b266bccea438909aa7b15a9deb 387 PIRSF PIRSF010361 2 387 4.4E-70 T 23-10-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane APE_1001.1 092ce1b266bccea438909aa7b15a9deb 387 Pfam PF09594 Glycosyltransferase family 87 75 289 5.6E-6 T 23-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 APE_1395.1 a4ca60ec2a44980e1b76dd6a906fd6bf 332 SUPERFAMILY SSF161098 91 317 1.02E-15 T 23-10-2018 IPR035906 MetI-like superfamily APE_1395.1 a4ca60ec2a44980e1b76dd6a906fd6bf 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 332 1.5E-37 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1395.1 a4ca60ec2a44980e1b76dd6a906fd6bf 332 Gene3D G3DSA:1.10.3720.10 87 325 1.4E-19 T 23-10-2018 IPR035906 MetI-like superfamily APE_1534 eeca5ee0c94665ead612d0dbcdfd5785 288 SUPERFAMILY SSF55729 8 137 3.54E-7 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase APE_1534 eeca5ee0c94665ead612d0dbcdfd5785 288 Gene3D G3DSA:3.40.630.30 5 160 9.5E-6 T 23-10-2018 APE_0973.1 beced49f8d12894e91c6d7a45d34c2db 338 Pfam PF06626 Protein of unknown function (DUF1152) 16 311 2.2E-106 T 23-10-2018 IPR010581 Protein of unknown function DUF1152 APE_0973.1 beced49f8d12894e91c6d7a45d34c2db 338 PIRSF PIRSF029122 7 338 2.3E-133 T 23-10-2018 IPR010581 Protein of unknown function DUF1152 APE_1964.1 0f0943d818dfb37864415f97485a860f 133 Pfam PF02036 SCP-2 sterol transfer family 13 116 6.6E-18 T 23-10-2018 IPR003033 SCP2 sterol-binding domain APE_1964.1 0f0943d818dfb37864415f97485a860f 133 Gene3D G3DSA:3.30.1050.10 5 128 1.1E-31 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily APE_1964.1 0f0943d818dfb37864415f97485a860f 133 SUPERFAMILY SSF55718 3 129 1.51E-32 T 23-10-2018 IPR036527 SCP2 sterol-binding domain superfamily APE_1190.1 59284b26da7e35bb70d37966dec6844b 206 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 11 148 2.8E-22 T 23-10-2018 IPR006342 Methyltransferase FkbM APE_1190.1 59284b26da7e35bb70d37966dec6844b 206 SUPERFAMILY SSF53335 8 172 9.58E-32 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1190.1 59284b26da7e35bb70d37966dec6844b 206 Gene3D G3DSA:3.40.50.150 3 177 4.0E-24 T 23-10-2018 APE_1190.1 59284b26da7e35bb70d37966dec6844b 206 Pfam PF05050 Methyltransferase FkbM domain 14 167 2.1E-14 T 23-10-2018 IPR006342 Methyltransferase FkbM APE_0540.1 fa41444ee41d80c1558360207c7384dc 389 Gene3D G3DSA:3.40.50.300 65 258 2.9E-12 T 23-10-2018 APE_0540.1 fa41444ee41d80c1558360207c7384dc 389 SUPERFAMILY SSF52540 84 226 7.64E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0540.1 fa41444ee41d80c1558360207c7384dc 389 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 89 252 6.0E-18 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain APE_0540.1 fa41444ee41d80c1558360207c7384dc 389 SUPERFAMILY SSF53795 84 126 2.56E-6 T 23-10-2018 APE_1677.1 41805cba8fc2fb2f33b194c0d765fd73 377 Pfam PF00676 Dehydrogenase E1 component 43 336 4.3E-81 T 23-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 APE_1677.1 41805cba8fc2fb2f33b194c0d765fd73 377 SUPERFAMILY SSF52518 17 357 6.77E-94 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_1677.1 41805cba8fc2fb2f33b194c0d765fd73 377 Gene3D G3DSA:3.40.50.970 4 374 1.9E-111 T 23-10-2018 APE_1677.1 41805cba8fc2fb2f33b194c0d765fd73 377 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 16 359 6.6E-130 T 23-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 APE_1495a ebe9029095d760c37b786861e345534d 78 SUPERFAMILY SSF47598 1 45 7.23E-11 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APE_1495a ebe9029095d760c37b786861e345534d 78 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 42 5.9E-12 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 APE_1495a ebe9029095d760c37b786861e345534d 78 Gene3D G3DSA:1.10.1220.10 9 45 3.8E-7 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 APE_0330.1 fc29941df576e0e12b3ea3e63342098c 334 SMART SM00849 22 239 1.2E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0330.1 fc29941df576e0e12b3ea3e63342098c 334 Pfam PF00753 Metallo-beta-lactamase superfamily 21 239 1.0E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase APE_0330.1 fc29941df576e0e12b3ea3e63342098c 334 SUPERFAMILY SSF56281 17 331 1.44E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0330.1 fc29941df576e0e12b3ea3e63342098c 334 Gene3D G3DSA:3.60.15.10 9 267 9.0E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like APE_0082.1 ea51535dc12871c8248e7ef8fd07f95d 394 SMART SM00933 69 358 1.1E-30 T 23-10-2018 IPR018977 NurA domain APE_0082.1 ea51535dc12871c8248e7ef8fd07f95d 394 Pfam PF09376 NurA domain 70 357 1.2E-21 T 23-10-2018 IPR018977 NurA domain APE_1510.1 6e173049bb576a7b449710e0df1dcabb 255 SUPERFAMILY SSF54631 7 124 1.29E-11 T 23-10-2018 APE_1510.1 6e173049bb576a7b449710e0df1dcabb 255 Pfam PF00571 CBS domain 79 124 4.9E-6 T 23-10-2018 IPR000644 CBS domain APE_1510.1 6e173049bb576a7b449710e0df1dcabb 255 Gene3D G3DSA:3.10.580.10 4 128 7.2E-11 T 23-10-2018 APE_0720a 110c9523fc4c4c9e3e35ae51d61cef52 81 Gene3D G3DSA:1.10.10.10 8 74 5.8E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_0720a 110c9523fc4c4c9e3e35ae51d61cef52 81 Pfam PF09339 IclR helix-turn-helix domain 12 58 3.1E-11 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 APE_0720a 110c9523fc4c4c9e3e35ae51d61cef52 81 SUPERFAMILY SSF46785 7 77 4.96E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0488.1 f83b2f9ce063311441e00bdc6deea4e8 185 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 5 181 2.8E-64 T 23-10-2018 IPR018700 Protein of unknown function DUF2204 APE_0488.1 f83b2f9ce063311441e00bdc6deea4e8 185 SUPERFAMILY SSF81301 12 148 4.9E-9 T 23-10-2018 APE_0663 98f3e4f7af9c8c01b5907d659f279b40 116 Pfam PF04434 SWIM zinc finger 34 77 3.2E-5 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 APE_0620a 8fe8fceff71f82a2768a54b1cf689a5d 88 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 76 4.4E-11 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core APE_0620a 8fe8fceff71f82a2768a54b1cf689a5d 88 SUPERFAMILY SSF101386 5 79 1.21E-18 T 23-10-2018 APE_0620a 8fe8fceff71f82a2768a54b1cf689a5d 88 Gene3D G3DSA:1.10.287.1080 1 79 2.4E-23 T 23-10-2018 APE_0789 a5864702630d0a1f6657f54ff0f6aafd 136 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 2 131 2.1E-35 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_0789 a5864702630d0a1f6657f54ff0f6aafd 136 Pfam PF01201 Ribosomal protein S8e 5 129 8.6E-30 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 APE_0789 a5864702630d0a1f6657f54ff0f6aafd 136 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 130 31.667 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_0789 a5864702630d0a1f6657f54ff0f6aafd 136 Gene3D G3DSA:2.40.10.310 61 136 3.0E-28 T 23-10-2018 APE_0789 a5864702630d0a1f6657f54ff0f6aafd 136 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 30 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 APE_1895.1 08d5dff5e4a7ea17e39128db2c891eea 551 Pfam PF00482 Type II secretion system (T2SS), protein F 321 450 6.5E-12 T 23-10-2018 IPR018076 Type II secretion system F domain APE_1895.1 08d5dff5e4a7ea17e39128db2c891eea 551 Pfam PF00482 Type II secretion system (T2SS), protein F 75 199 1.6E-7 T 23-10-2018 IPR018076 Type II secretion system F domain APE_0320.1 7923b5dd4670669bb3585398bebc4a8d 110 Gene3D G3DSA:3.30.70.20 1 79 2.6E-14 T 23-10-2018 APE_0320.1 7923b5dd4670669bb3585398bebc4a8d 110 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 17 28 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0320.1 7923b5dd4670669bb3585398bebc4a8d 110 SUPERFAMILY SSF54862 9 81 2.29E-19 T 23-10-2018 APE_0320.1 7923b5dd4670669bb3585398bebc4a8d 110 Pfam PF00037 4Fe-4S binding domain 11 33 2.4E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_0199.1 fcf7604bb3d1ce2795fbbf96dab256fc 406 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 87 232 6.9E-7 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like APE_2242.1 86fe38bf61ee59add66a6a32c586f296 279 Pfam PF01883 Iron-sulfur cluster assembly protein 4 77 1.1E-11 T 23-10-2018 IPR002744 MIP18 family-like APE_2242.1 86fe38bf61ee59add66a6a32c586f296 279 Gene3D G3DSA:3.30.300.130 2 99 8.1E-16 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APE_2242.1 86fe38bf61ee59add66a6a32c586f296 279 SUPERFAMILY SSF117916 2 84 1.57E-15 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APE_2411.1 d541d51c61a30e054ebc59129e64a279 184 PIRSF PIRSF024534 5 177 9.7E-67 T 23-10-2018 IPR012652 Energy coupling factor transporter S component ThiW APE_2411.1 d541d51c61a30e054ebc59129e64a279 184 Pfam PF09512 Thiamine-precursor transporter protein (ThiW) 12 167 3.5E-45 T 23-10-2018 IPR012652 Energy coupling factor transporter S component ThiW APE_2411.1 d541d51c61a30e054ebc59129e64a279 184 Gene3D G3DSA:1.10.1760.20 9 172 2.4E-8 T 23-10-2018 APE_2411.1 d541d51c61a30e054ebc59129e64a279 184 TIGRFAM TIGR02359 thiW: energy coupling factor transporter S component ThiW 10 172 1.9E-60 T 23-10-2018 IPR012652 Energy coupling factor transporter S component ThiW APE_2328a e46445c27044b8ceb81b60e233a5187b 95 Gene3D G3DSA:3.30.1740.20 1 94 5.6E-24 T 23-10-2018 IPR038551 Ribosomal protein S26e superfamily APE_2328a e46445c27044b8ceb81b60e233a5187b 95 Pfam PF01283 Ribosomal protein S26e 1 91 6.5E-22 T 23-10-2018 IPR000892 Ribosomal protein S26e GO:0003735|GO:0005622|GO:0005840|GO:0006412 APE_2064.1 d769edb9286070d98b2f930f62dcea2a 325 Gene3D G3DSA:3.30.1360.170 10 269 1.0E-48 T 23-10-2018 APE_2064.1 d769edb9286070d98b2f930f62dcea2a 325 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 272 24.947 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APE_2064.1 d769edb9286070d98b2f930f62dcea2a 325 Pfam PF02511 Thymidylate synthase complementing protein 15 258 3.0E-57 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APE_2064.1 d769edb9286070d98b2f930f62dcea2a 325 SUPERFAMILY SSF69796 10 269 9.02E-51 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 APE_1564.1 5ae54f564f1e49503e7d9e4b26e93698 214 SUPERFAMILY SSF88723 113 201 5.89E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_1564.1 5ae54f564f1e49503e7d9e4b26e93698 214 Pfam PF08745 PINc domain ribonuclease 13 202 2.1E-62 T 23-10-2018 IPR014856 PIN-domain ribonuclease APE_1564.1 5ae54f564f1e49503e7d9e4b26e93698 214 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 13 204 7.8E-69 T 23-10-2018 IPR014856 PIN-domain ribonuclease APE_1564.1 5ae54f564f1e49503e7d9e4b26e93698 214 Hamap MF_01078 UPF0278 protein . 10 209 30.921 T 23-10-2018 IPR014856 PIN-domain ribonuclease APE_1690.1 2747f1eb2eb6d69b00c7f37d0958bcf7 210 Gene3D G3DSA:1.10.3450.10 93 173 3.6E-6 T 23-10-2018 APE_1690.1 2747f1eb2eb6d69b00c7f37d0958bcf7 210 SUPERFAMILY SSF140663 92 171 7.46E-11 T 23-10-2018 IPR023203 TTHA0068-like superfamily APE_1690.1 2747f1eb2eb6d69b00c7f37d0958bcf7 210 Pfam PF03745 Domain of unknown function (DUF309) 96 144 9.0E-8 T 23-10-2018 IPR005500 Protein of unknown function DUF309 APE_1417.1 cda5994229012c639347bbabf257dfb8 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 96 3.6E-11 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like APE_0716.1 3a842ef08acbbbcb231f50f27d266c7b 315 Pfam PF16795 Archaeal phage integrase 138 298 5.4E-55 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal APE_0716.1 3a842ef08acbbbcb231f50f27d266c7b 315 Gene3D G3DSA:1.10.443.10 134 302 4.0E-30 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 APE_0957 0694930dc2afe201db2c1b59efa1ef90 261 Hamap MF_00722 Endonuclease NucS [nucS]. 35 248 33.545 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 APE_0957 0694930dc2afe201db2c1b59efa1ef90 261 Gene3D G3DSA:3.40.1350.10 132 242 3.4E-32 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 APE_0957 0694930dc2afe201db2c1b59efa1ef90 261 Pfam PF01939 Endonuclease NucS 34 242 1.1E-43 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 APE_0957 0694930dc2afe201db2c1b59efa1ef90 261 Gene3D G3DSA:2.70.180.20 10 129 3.0E-27 T 23-10-2018 APE_0739 848f10795de99a53050528d1c6c6088f 345 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 191 335 3.7E-31 T 23-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 APE_0739 848f10795de99a53050528d1c6c6088f 345 SUPERFAMILY SSF47203 191 337 1.13E-31 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 APE_0739 848f10795de99a53050528d1c6c6088f 345 SUPERFAMILY SSF56645 11 181 1.83E-23 T 23-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 APE_0739 848f10795de99a53050528d1c6c6088f 345 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 90 179 9.2E-11 T 23-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 APE_0739 848f10795de99a53050528d1c6c6088f 345 Gene3D G3DSA:1.20.140.10 194 340 2.0E-32 T 23-10-2018 APE_0739 848f10795de99a53050528d1c6c6088f 345 Gene3D G3DSA:2.40.110.10 89 193 5.2E-14 T 23-10-2018 APE_1824 5e93571e424f885f20073bcb312ee01d 385 Pfam PF05559 Protein of unknown function (DUF763) 3 342 3.0E-103 T 23-10-2018 IPR008482 Protein of unknown function DUF763 APE_2110 34c4dcb2bf685a87bc9dacb466335bad 247 Hamap MF_02088 Probable queuosine precursor transporter. 8 234 17.622 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 APE_2110 34c4dcb2bf685a87bc9dacb466335bad 247 Pfam PF02592 Putative vitamin uptake transporter 49 221 4.9E-52 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 APE_2110 34c4dcb2bf685a87bc9dacb466335bad 247 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 16 228 7.4E-73 T 23-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 APE_2086a 50c6fb10e5e4bee37a6c6cb83b813080 74 SUPERFAMILY SSF54285 11 74 1.26E-8 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp APE_2086a 50c6fb10e5e4bee37a6c6cb83b813080 74 Gene3D G3DSA:3.10.20.30 3 74 4.4E-16 T 23-10-2018 IPR012675 Beta-grasp domain superfamily APE_0760.1 468f791948a4a1936fa3894452f91784 135 SMART SM00748 9 120 9.3E-41 T 23-10-2018 IPR007842 HEPN domain APE_0760.1 468f791948a4a1936fa3894452f91784 135 SUPERFAMILY SSF81593 3 126 1.73E-34 T 23-10-2018 APE_0760.1 468f791948a4a1936fa3894452f91784 135 Pfam PF05168 HEPN domain 7 126 5.0E-31 T 23-10-2018 IPR007842 HEPN domain APE_0760.1 468f791948a4a1936fa3894452f91784 135 Gene3D G3DSA:1.20.120.330 2 130 4.6E-32 T 23-10-2018 APE_0109.1 930653562ec74d47f97919536b49dc8b 401 Pfam PF09376 NurA domain 50 375 1.8E-45 T 23-10-2018 IPR018977 NurA domain APE_0109.1 930653562ec74d47f97919536b49dc8b 401 SMART SM00933 49 375 8.4E-37 T 23-10-2018 IPR018977 NurA domain APE_2177.1 7c4ca66b1c59aea22ed96496e8638ac8 171 SUPERFAMILY SSF88723 16 80 1.11E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily APE_2177.1 7c4ca66b1c59aea22ed96496e8638ac8 171 Pfam PF01927 Mut7-C RNAse domain 13 159 1.5E-50 T 23-10-2018 IPR002782 Mut7-C RNAse domain APE_0339.1 e22ee7193c2392c8ccbd3f2b72606ebc 363 SUPERFAMILY SSF75005 53 350 3.03E-34 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily APE_0339.1 e22ee7193c2392c8ccbd3f2b72606ebc 363 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 24 352 5.7E-119 T 23-10-2018 IPR007184 Mannoside phosphorylase APE_0339.1 e22ee7193c2392c8ccbd3f2b72606ebc 363 Gene3D G3DSA:2.115.10.20 68 360 1.0E-32 T 23-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily APE_2341 cef2eb0aebc5ec2e19c49cc80dfa0f57 264 Gene3D G3DSA:3.30.930.10 1 241 1.1E-49 T 23-10-2018 APE_2341 cef2eb0aebc5ec2e19c49cc80dfa0f57 264 SUPERFAMILY SSF55681 3 238 5.82E-47 T 23-10-2018 APE_2341 cef2eb0aebc5ec2e19c49cc80dfa0f57 264 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 154 9.8E-7 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 105 123 3.3E-14 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 84 104 3.3E-14 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 132 147 3.3E-14 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 Gene3D G3DSA:3.10.20.30 311 389 8.6E-32 T 23-10-2018 IPR012675 Beta-grasp domain superfamily APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 SUPERFAMILY SSF81271 310 387 2.09E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 SUPERFAMILY SSF52540 85 325 5.78E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 314 1.8E-12 T 23-10-2018 IPR031662 GTP binding protein, second domain APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 Pfam PF02824 TGS domain 316 387 2.2E-23 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 APE_2052.1 737c5c73f97eb043e33d9b84d335bc48 389 Pfam PF01926 50S ribosome-binding GTPase 84 183 3.8E-17 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 APE_0002 346358fdff0d11bfa1cdd74d7df4ef96 112 SUPERFAMILY SSF46785 5 103 7.87E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_0002 346358fdff0d11bfa1cdd74d7df4ef96 112 Pfam PF03551 Transcriptional regulator PadR-like family 20 91 8.7E-23 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal APE_0002 346358fdff0d11bfa1cdd74d7df4ef96 112 Gene3D G3DSA:1.10.10.10 2 107 1.2E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1326.1 8d93ce24a1c39a93503b3f2307b2b7be 383 Gene3D G3DSA:3.20.20.70 47 367 5.0E-6 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_1326.1 8d93ce24a1c39a93503b3f2307b2b7be 383 SUPERFAMILY SSF102114 43 246 4.05E-10 T 23-10-2018 APE_1555.1 6805565a2fb589860a57717521cbd33d 335 SUPERFAMILY SSF81340 6 285 2.49E-48 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APE_1555.1 6805565a2fb589860a57717521cbd33d 335 Pfam PF00654 Voltage gated chloride channel 73 284 2.8E-47 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 APE_1555.1 6805565a2fb589860a57717521cbd33d 335 Gene3D G3DSA:1.10.3080.10 2 295 1.5E-47 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 APE_1817.1 2089ec6031c821e31434c7c56eff701b 142 Pfam PF10051 Uncharacterized protein conserved in archaea (DUF2286) 2 136 4.0E-42 T 23-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 APE_0183.1 c150948fa2fb59456275bb4790e51e17 266 Pfam PF01925 Sulfite exporter TauE/SafE 17 264 1.3E-48 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 APE_2436 f398ec5c1fadd25af55d7928aafd659c 375 Gene3D G3DSA:3.20.20.140 56 330 1.4E-30 T 23-10-2018 APE_2436 f398ec5c1fadd25af55d7928aafd659c 375 Pfam PF01979 Amidohydrolase family 179 292 1.0E-10 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APE_2436 f398ec5c1fadd25af55d7928aafd659c 375 SUPERFAMILY SSF51556 53 316 6.13E-36 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_1868.1 ef279883346af0bd39e2a4f37a855b4b 251 Pfam PF04254 Protein of unknown function (DUF432) 79 186 1.0E-20 T 23-10-2018 IPR007366 Protein of unknown function DUF432 APE_0087.1 27339ccd01c7f02ca3904a0f6df41a50 104 Pfam PF09943 Uncharacterized protein conserved in archaea (DUF2175) 4 99 2.6E-31 T 23-10-2018 IPR018686 Protein of unknown function DUF2175 APE_2514 d52e6caf3190aabfb0d0136c51327b97 275 PIRSF PIRSF006648 12 264 1.7E-19 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2514 d52e6caf3190aabfb0d0136c51327b97 275 Pfam PF01061 ABC-2 type transporter 14 228 5.1E-13 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APE_2514 d52e6caf3190aabfb0d0136c51327b97 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 28 49 7.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2514 d52e6caf3190aabfb0d0136c51327b97 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 7.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2514 d52e6caf3190aabfb0d0136c51327b97 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 149 173 7.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_2514 d52e6caf3190aabfb0d0136c51327b97 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 7.3E-9 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 APE_0673.1 02999f59709bb2ad3cc477c189f0abe1 685 Pfam PF01496 V-type ATPase 116kDa subunit family 247 507 4.0E-15 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_0673.1 02999f59709bb2ad3cc477c189f0abe1 685 Pfam PF01496 V-type ATPase 116kDa subunit family 574 672 1.0E-14 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 APE_1763 529acc175c127748574dd8ef5df2512e 178 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 20 168 1.9E-52 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 APE_0219 9134952f345708b621c8129ad16bb731 461 SUPERFAMILY SSF52540 195 448 1.7E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_0219 9134952f345708b621c8129ad16bb731 461 SMART SM00382 229 403 4.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain APE_0219 9134952f345708b621c8129ad16bb731 461 Pfam PF01935 Domain of unknown function DUF87 216 280 3.4E-5 T 23-10-2018 IPR002789 Helicase HerA, central domain APE_0219 9134952f345708b621c8129ad16bb731 461 Gene3D G3DSA:3.40.50.300 203 441 3.7E-27 T 23-10-2018 APE_0609.1 885233f93b11d2b4b871347b3f0b11f8 1550 Gene3D G3DSA:1.20.5.1070 1448 1517 1.6E-5 T 23-10-2018 APE_2605.1 43b9f60ee48679e93fd1212f686b2f89 233 SUPERFAMILY SSF54862 52 225 7.95E-68 T 23-10-2018 APE_2605.1 43b9f60ee48679e93fd1212f686b2f89 233 Pfam PF13247 4Fe-4S dicluster domain 99 192 3.6E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain APE_2605.1 43b9f60ee48679e93fd1212f686b2f89 233 Gene3D G3DSA:3.30.70.20 37 93 6.3E-8 T 23-10-2018 APE_2605.1 43b9f60ee48679e93fd1212f686b2f89 233 Gene3D G3DSA:3.30.70.20 94 233 5.5E-57 T 23-10-2018 APE_2605.1 43b9f60ee48679e93fd1212f686b2f89 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 137 148 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site APE_0891 8005fd696934405878931bb998290328 162 Pfam PF05425 Copper resistance protein D 52 157 1.8E-18 T 23-10-2018 IPR008457 Copper resistance protein D GO:0016021 APE_2129.1 b6d1ceabc22c660d57ba3b5d35184fa5 155 Pfam PF08905 Domain of unknown function (DUF1850) 53 127 6.5E-7 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 APE_0890 3729bb6a533398524c3597a586d44a96 156 Pfam PF11848 Domain of unknown function (DUF3368) 98 144 6.5E-14 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 APE_1932.1 8c308f3d706429e34d91559dd38d546f 406 Pfam PF12698 ABC-2 family transporter protein 22 394 2.9E-19 T 23-10-2018 APE_1630.1 ad7e04dd39582d95b2719a9ea7e45461 477 SUPERFAMILY SSF53850 90 461 9.93E-56 T 23-10-2018 APE_1630.1 ad7e04dd39582d95b2719a9ea7e45461 477 Pfam PF01547 Bacterial extracellular solute-binding protein 90 376 2.1E-39 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein APE_1630.1 ad7e04dd39582d95b2719a9ea7e45461 477 Gene3D G3DSA:3.40.190.10 56 460 3.3E-48 T 23-10-2018 APE_0493.1 fdcac2c11913cfcb0fa1334fb1c7aa6b 316 SUPERFAMILY SSF100950 32 279 1.34E-19 T 23-10-2018 IPR037171 NagB/RpiA transferase-like APE_0493.1 fdcac2c11913cfcb0fa1334fb1c7aa6b 316 Pfam PF01008 Initiation factor 2 subunit family 90 229 2.4E-6 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 APE_0493.1 fdcac2c11913cfcb0fa1334fb1c7aa6b 316 Gene3D G3DSA:3.40.50.10470 113 284 1.7E-12 T 23-10-2018 APE_0955 fd3762f6ebdf0414580b2af768a4060a 295 SUPERFAMILY SSF81324 35 250 8.72E-47 T 23-10-2018 APE_0955 fd3762f6ebdf0414580b2af768a4060a 295 Pfam PF00520 Ion transport protein 62 251 8.1E-18 T 23-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 APE_0955 fd3762f6ebdf0414580b2af768a4060a 295 Gene3D G3DSA:1.10.287.70 36 253 2.1E-78 T 23-10-2018 APE_0536.1 278113a98305883002348487dd097526 327 Gene3D G3DSA:3.20.20.80 157 288 1.5E-6 T 23-10-2018 APE_0536.1 278113a98305883002348487dd097526 327 Gene3D G3DSA:3.20.20.80 1 147 5.8E-25 T 23-10-2018 APE_0833.1 75e75e24d0aa6a5be9f1a48aa7c379bf 267 SUPERFAMILY SSF52540 36 169 8.79E-6 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1939.1 90fc3acdb285819014a7e794fd8e6fb8 279 PIRSF PIRSF016896 1 279 2.2E-74 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 APE_2128 013a1bf260afd50daba8c70a717570b8 318 Gene3D G3DSA:3.40.50.970 26 202 2.8E-26 T 23-10-2018 APE_2128 013a1bf260afd50daba8c70a717570b8 318 SUPERFAMILY SSF52518 14 250 2.95E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold APE_2128 013a1bf260afd50daba8c70a717570b8 318 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 16 303 2.2E-144 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate APE_2128 013a1bf260afd50daba8c70a717570b8 318 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 197 2.4E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 APE_2128 013a1bf260afd50daba8c70a717570b8 318 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 201 274 3.7E-22 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal APE_2499.1 c79740afd8642bab5a517e432065abb8 134 Pfam PF03061 Thioesterase superfamily 40 109 2.3E-6 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 APE_2499.1 c79740afd8642bab5a517e432065abb8 134 Gene3D G3DSA:3.10.129.10 2 133 1.6E-37 T 23-10-2018 APE_2499.1 c79740afd8642bab5a517e432065abb8 134 SUPERFAMILY SSF54637 8 130 1.91E-30 T 23-10-2018 IPR029069 HotDog domain superfamily APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 PIRSF PIRSF000103 2 289 3.7E-76 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 Gene3D G3DSA:3.40.50.720 2 157 2.2E-33 T 23-10-2018 APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 SUPERFAMILY SSF51735 4 158 2.85E-28 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 SUPERFAMILY SSF48179 161 283 1.13E-18 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 162 280 6.4E-13 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 Gene3D G3DSA:1.10.1040.10 158 285 2.3E-17 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 APE_0756.1 2f99b6e526749414fffa5c2e827a4ec7 291 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 156 7.8E-23 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 APE_1240.1 b9a3a402769b764b1311fc5d0df9a059 327 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 319 2.8E-92 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 APE_1240.1 b9a3a402769b764b1311fc5d0df9a059 327 Gene3D G3DSA:3.100.10.20 2 80 2.9E-17 T 23-10-2018 APE_1240.1 b9a3a402769b764b1311fc5d0df9a059 327 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 312 23.684 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 APE_1240.1 b9a3a402769b764b1311fc5d0df9a059 327 Pfam PF01867 CRISPR associated protein Cas1 4 253 4.6E-59 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 APE_1240.1 b9a3a402769b764b1311fc5d0df9a059 327 Gene3D G3DSA:1.20.120.920 82 324 3.0E-53 T 23-10-2018 APE_1305 a4d35a04185c599dfff564e5cf2636aa 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 278 1.2E-26 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_2195 be85815cd09bd21e474bbe87950776b2 141 Pfam PF01886 Protein of unknown function DUF61 18 135 3.2E-16 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 APE_2195 be85815cd09bd21e474bbe87950776b2 141 PIRSF PIRSF024484 10 141 7.8E-63 T 23-10-2018 IPR012357 Uncharacterised conserved protein UCP024484 APE_1477 429738b8551cc4eaeb1d7220021b0fa4 308 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 191 286 4.0E-48 T 23-10-2018 IPR005642 Lysine exporter LysO APE_1477 429738b8551cc4eaeb1d7220021b0fa4 308 Pfam PF03956 Lysine exporter LysO 118 300 7.8E-43 T 23-10-2018 IPR005642 Lysine exporter LysO APE_1000.1 f766b8b728bc323b47fe054722d73c92 151 Pfam PF03168 Late embryogenesis abundant protein 55 149 7.3E-12 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup APE_0803.1 de6f0e46dacb475dbade7fde4dc98e3d 408 SUPERFAMILY SSF51717 153 357 5.49E-5 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 APE_0416b.1 5e2f573b4e244f1e99eadfd38501383b 57 Gene3D G3DSA:1.10.1220.10 17 57 1.9E-7 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 APE_0416b.1 5e2f573b4e244f1e99eadfd38501383b 57 SUPERFAMILY SSF47598 17 55 1.08E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 APE_0416b.1 5e2f573b4e244f1e99eadfd38501383b 57 Pfam PF01402 Ribbon-helix-helix protein, copG family 19 54 5.5E-11 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 APE_1196.1 9f3825951112d6c31210b07b6b7c3153 265 Pfam PF01925 Sulfite exporter TauE/SafE 13 247 2.2E-27 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 APE_2269.1 685d6b7c9a7fd2e7e6d22aa354d54ff6 382 SUPERFAMILY SSF103473 2 379 4.32E-32 T 23-10-2018 IPR036259 MFS transporter superfamily APE_2269.1 685d6b7c9a7fd2e7e6d22aa354d54ff6 382 Pfam PF07690 Major Facilitator Superfamily 10 341 4.8E-22 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 APE_2269.1 685d6b7c9a7fd2e7e6d22aa354d54ff6 382 TIGRFAM TIGR00903 2A0129: major facilitator 4 family protein 15 382 3.2E-208 T 23-10-2018 IPR005277 Uncharacterised protein family, Major Facilitator Superfamily MSF4 APE_2269.1 685d6b7c9a7fd2e7e6d22aa354d54ff6 382 Gene3D G3DSA:1.20.1250.20 2 379 1.1E-26 T 23-10-2018 APE_1711 d0a943e4c47365e70047e47ed2e7a7fe 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 249 265 2.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_1711 d0a943e4c47365e70047e47ed2e7a7fe 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 277 296 2.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 APE_1711 d0a943e4c47365e70047e47ed2e7a7fe 319 Gene3D G3DSA:1.10.10.10 243 300 2.9E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1711 d0a943e4c47365e70047e47ed2e7a7fe 319 Pfam PF13412 Winged helix-turn-helix DNA-binding 249 297 4.1E-9 T 23-10-2018 APE_1711 d0a943e4c47365e70047e47ed2e7a7fe 319 SUPERFAMILY SSF46785 248 303 1.31E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_2190 d71755b5d3251f2a024ed3604af73c97 354 SUPERFAMILY SSF64182 8 331 1.45E-11 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily APE_1720 cccdc742bd7e02b86658466006a5dbae 196 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 103 153 - T 23-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1720 cccdc742bd7e02b86658466006a5dbae 196 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 84 154 6.5E-8 T 23-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 APE_1720 cccdc742bd7e02b86658466006a5dbae 196 SUPERFAMILY SSF49503 68 159 6.86E-24 T 23-10-2018 IPR008972 Cupredoxin APE_1720 cccdc742bd7e02b86658466006a5dbae 196 Gene3D G3DSA:2.60.40.420 28 160 3.9E-27 T 23-10-2018 IPR008972 Cupredoxin APE_2240 6eb2f9330714baf5d284d2b611b75402 324 Gene3D G3DSA:3.20.20.140 37 303 2.4E-31 T 23-10-2018 APE_2240 6eb2f9330714baf5d284d2b611b75402 324 SUPERFAMILY SSF51556 11 296 5.35E-32 T 23-10-2018 IPR032466 Metal-dependent hydrolase APE_2240 6eb2f9330714baf5d284d2b611b75402 324 Pfam PF04909 Amidohydrolase 6 295 1.2E-40 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 APE_1410.1 ef867142638f5632a5a7eee394ae7027 461 Pfam PF00361 Proton-conducting membrane transporter 133 408 5.8E-23 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 APE_0370 f439da6f29009edf8ed0993fc2e89139 659 SUPERFAMILY SSF53300 504 617 2.86E-8 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily APE_0370 f439da6f29009edf8ed0993fc2e89139 659 Pfam PF05762 VWA domain containing CoxE-like protein 470 635 2.6E-15 T 23-10-2018 IPR008912 Uncharacterised protein family CoxE-like APE_0136.1 0b4d9f743634e406bf831cbc990eb2ae 376 PIRSF PIRSF019205 8 368 9.8E-155 T 23-10-2018 IPR012443 Protein of unknown function DUF1646 APE_0136.1 0b4d9f743634e406bf831cbc990eb2ae 376 Pfam PF07854 Protein of unknown function (DUF1646) 16 368 7.1E-160 T 23-10-2018 IPR012443 Protein of unknown function DUF1646 APE_2310.1 1b4bea8e51cbc8f1c289235dd28a3d36 383 Gene3D G3DSA:3.90.1200.10 116 375 8.1E-43 T 23-10-2018 APE_2310.1 1b4bea8e51cbc8f1c289235dd28a3d36 383 Pfam PF01636 Phosphotransferase enzyme family 54 279 3.2E-10 T 23-10-2018 IPR002575 Aminoglycoside phosphotransferase APE_2310.1 1b4bea8e51cbc8f1c289235dd28a3d36 383 SUPERFAMILY SSF56112 49 281 6.65E-19 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily APE_2311.1 59b90a41c441e0f977202d64789f14c9 299 Pfam PF10977 Protein of unknown function (DUF2797) 135 205 1.7E-6 T 23-10-2018 IPR021246 Protein of unknown function DUF2797 APE_2155.1 2255b2cb447a5c8710987c903d18799d 243 Pfam PF02361 Cobalt transport protein 35 213 1.0E-9 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component APE_0290a 4be4db8075f3082b40bfe69b00493a7b 71 Gene3D G3DSA:3.40.30.10 2 68 3.0E-7 T 23-10-2018 APE_0290a 4be4db8075f3082b40bfe69b00493a7b 71 SUPERFAMILY SSF52833 6 59 1.56E-9 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1722 c9415132701e8c72ccd7e6edf84295a5 389 Gene3D G3DSA:3.40.30.10 40 147 2.1E-15 T 23-10-2018 APE_1722 c9415132701e8c72ccd7e6edf84295a5 389 SUPERFAMILY SSF52833 46 164 5.69E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily APE_1722 c9415132701e8c72ccd7e6edf84295a5 389 Pfam PF00085 Thioredoxin 59 142 7.8E-8 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 APE_1662.1 a644d306da902742b4d1c6faf5647200 159 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 8 91 1.0E-42 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal APE_1662.1 a644d306da902742b4d1c6faf5647200 159 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 99 8.0E-28 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal APE_1662.1 a644d306da902742b4d1c6faf5647200 159 Gene3D G3DSA:2.30.30.20 102 154 1.7E-15 T 23-10-2018 APE_1662.1 a644d306da902742b4d1c6faf5647200 159 SUPERFAMILY SSF57825 106 157 1.96E-12 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily APE_1662.1 a644d306da902742b4d1c6faf5647200 159 SUPERFAMILY SSF54893 4 102 4.19E-29 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily APE_1662.1 a644d306da902742b4d1c6faf5647200 159 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 3 155 30.839 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 APE_1662.1 a644d306da902742b4d1c6faf5647200 159 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 106 153 2.2E-13 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal APE_1662.1 a644d306da902742b4d1c6faf5647200 159 Gene3D G3DSA:3.30.70.140 1 101 1.3E-30 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily APE_1304.1 9547c52c5310c815a674b061a6eef225 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 319 1.9E-32 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_1517a beb72fc969fc4fa1adf35a6da97f8f88 108 SMART SM01357 67 99 2.6E-11 T 23-10-2018 IPR029227 Plant antimicrobial peptide GO:0050832 APE_2490.1 486ef579fe72c62aea46efc59356acf4 276 Pfam PF03239 Iron permease FTR1 family 5 267 1.4E-64 T 23-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 APE_0932.1 4368df04ef3b65120cdce3a9dab0bc59 320 Pfam PF04055 Radical SAM superfamily 33 193 1.2E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 APE_0932.1 4368df04ef3b65120cdce3a9dab0bc59 320 Gene3D G3DSA:3.80.30.30 78 225 3.8E-7 T 23-10-2018 APE_0932.1 4368df04ef3b65120cdce3a9dab0bc59 320 SUPERFAMILY SSF102114 14 245 1.12E-8 T 23-10-2018 APE_2154b 1141fdb52c6811a69546acdfaf684562 77 Gene3D G3DSA:3.40.50.300 1 75 1.9E-13 T 23-10-2018 APE_2154b 1141fdb52c6811a69546acdfaf684562 77 SUPERFAMILY SSF52540 1 64 6.14E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_2435 c89cb9bcca914e963eb6fda3e603583f 255 Pfam PF09973 Predicted membrane protein (DUF2208) 9 243 1.9E-74 T 23-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane APE_2435 c89cb9bcca914e963eb6fda3e603583f 255 PIRSF PIRSF014484 1 255 1.1E-110 T 23-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane APE_1189.1 b80c7237fa8a80113166a6cd31c17c45 283 Gene3D G3DSA:3.90.550.10 3 248 4.2E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1189.1 b80c7237fa8a80113166a6cd31c17c45 283 SUPERFAMILY SSF53448 17 216 7.74E-36 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1189.1 b80c7237fa8a80113166a6cd31c17c45 283 Pfam PF00535 Glycosyl transferase family 2 20 123 2.8E-24 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APE_0207 4ffb1c2aa585aa2b28074b0396436787 129 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 13 51 7.7E-13 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 APE_0207 4ffb1c2aa585aa2b28074b0396436787 129 Hamap MF_00343 UPF0148 protein . 8 116 22.0 T 23-10-2018 IPR022954 Uncharacterised protein family UPF0148 APE_0143.1 621435eb720fbaaea93ee72b669d4cad 223 Pfam PF03357 Snf7 39 206 5.7E-7 T 23-10-2018 IPR005024 Snf7 family GO:0007034 APE_0889.1 76ebbe07eb94c4eeed427f69480af7e6 388 TIGRFAM TIGR02460 osmo_MPGsynth: mannosyl-3-phosphoglycerate synthase 2 377 1.8E-182 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 APE_0889.1 76ebbe07eb94c4eeed427f69480af7e6 388 Gene3D G3DSA:3.90.550.10 1 387 3.0E-117 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0889.1 76ebbe07eb94c4eeed427f69480af7e6 388 Pfam PF09488 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) 6 366 7.4E-121 T 23-10-2018 IPR012812 Mannosyl-3-phosphoglycerate synthase GO:0005737|GO:0050504|GO:0051479 KEGG: 00051+2.4.1.217|MetaCyc: PWY-5656 APE_0824 43bcfafa97c7dbe8309599c08918f3e4 233 Pfam PF01435 Peptidase family M48 70 190 5.1E-12 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 APE_0444.1 4ffd0c23a28ece6d5ef6cc7bdcb9eae8 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 15 201 6.4E-55 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 APE_0650a.1 f1b8226371a1aa995539ed67011b270c 59 Pfam PF03911 Sec61beta family 15 54 1.8E-13 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 APE_0650a.1 f1b8226371a1aa995539ed67011b270c 59 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 3 55 15.207 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG APE_1237.1 3575c87b9114306099ec4ee5fe58f62e 240 SUPERFAMILY SSF46785 171 237 4.1E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1237.1 3575c87b9114306099ec4ee5fe58f62e 240 Gene3D G3DSA:1.10.10.10 171 238 6.6E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily APE_1237.1 3575c87b9114306099ec4ee5fe58f62e 240 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 10 234 4.6E-71 T 23-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 APE_1956a.1 f4ddeda0b342ac9fe47dedc19a6591c0 66 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 36 57 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 APE_1632 24ae3f7b2056d1d30d8aa76c34e4e6c3 288 Gene3D G3DSA:1.10.3720.10 60 286 3.3E-37 T 23-10-2018 IPR035906 MetI-like superfamily APE_1632 24ae3f7b2056d1d30d8aa76c34e4e6c3 288 SUPERFAMILY SSF161098 10 285 1.83E-35 T 23-10-2018 IPR035906 MetI-like superfamily APE_1719.1 6dd03aa3c814673717a3b4a623f7707b 190 SUPERFAMILY SSF46626 31 125 6.1E-5 T 23-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 APE_2607 0d98132bd458e4797d53d6d01317b698 404 Pfam PF03916 Polysulphide reductase, NrfD 25 347 5.8E-72 T 23-10-2018 IPR005614 NrfD family APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 SUPERFAMILY SSF51735 6 260 1.97E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 Gene3D G3DSA:3.40.50.720 1 260 6.7E-71 T 23-10-2018 APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.6E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.6E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.6E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 7.6E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 7.6E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.6E-30 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR APE_0912 a7b80bd685d619f95bcaad8f3a8a7b14 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 259 1.9E-47 T 23-10-2018 APE_1723.1 0ccd8944aa2fe480cca4ccd8604cf1bc 201 Gene3D G3DSA:3.40.50.150 4 200 1.0E-25 T 23-10-2018 APE_1723.1 0ccd8944aa2fe480cca4ccd8604cf1bc 201 SUPERFAMILY SSF53335 20 172 1.69E-16 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase APE_1723.1 0ccd8944aa2fe480cca4ccd8604cf1bc 201 Pfam PF01596 O-methyltransferase 75 164 3.3E-8 T 23-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 APE_0577 98babb6b6fe5fe44360dcf85c4745285 222 Gene3D G3DSA:3.20.20.70 3 217 5.0E-11 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 APE_0577 98babb6b6fe5fe44360dcf85c4745285 222 Pfam PF01487 Type I 3-dehydroquinase 27 214 1.6E-9 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APE_0577 98babb6b6fe5fe44360dcf85c4745285 222 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 6 217 26.01 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 APE_0577 98babb6b6fe5fe44360dcf85c4745285 222 SUPERFAMILY SSF51569 7 214 4.03E-12 T 23-10-2018 APE_1582 989b8ad374450b4bdc36f36279070374 363 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 144 359 1.8E-39 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 APE_1582 989b8ad374450b4bdc36f36279070374 363 SUPERFAMILY SSF161098 120 342 2.22E-17 T 23-10-2018 IPR035906 MetI-like superfamily APE_2587.1 daddcdb3fac3780641604b06a0afe368 359 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 336 7.6E-39 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_1808 32ca687cde30dc2a450890aab4df5af6 163 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 151 1.5E-14 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase APE_1866.1 8f0f7af98dc2ecc42a0ca4aadb0fdff3 234 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 4 80 3.1E-31 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 APE_0004 3f45df9837293f564aa58a739e2f4fc4 304 Pfam PF02517 CAAX protease self-immunity 151 260 1.2E-12 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 APE_2334.1 5026750b93d3720a1cde5dc9171f2091 239 Pfam PF04981 NMD3 family 7 230 1.5E-34 T 23-10-2018 IPR007064 Nmd3, N-terminal APE_1192 0635a688e9733a2e183fd7b2519b7c92 290 Pfam PF00535 Glycosyl transferase family 2 4 137 1.9E-10 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 APE_1192 0635a688e9733a2e183fd7b2519b7c92 290 Gene3D G3DSA:3.90.550.10 2 245 2.8E-24 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_1192 0635a688e9733a2e183fd7b2519b7c92 290 SUPERFAMILY SSF53448 2 217 9.98E-22 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases APE_0266a.1 0a85832330af03bf23e0938e52f4aecb 84 Pfam PF01998 Protein of unknown function DUF131 30 76 1.3E-13 T 23-10-2018 IPR002849 Protein of unknown function DUF131 APE_2246.1 ba8edb644161ec3c0872afea65fcdd69 178 Pfam PF04343 Protein of unknown function, DUF488 17 144 7.3E-30 T 23-10-2018 IPR007438 Protein of unknown function DUF488 APE_2246.1 ba8edb644161ec3c0872afea65fcdd69 178 PIRSF PIRSF024492 1 178 1.5E-59 T 23-10-2018 IPR014519 Uncharacterised conserved protein UCP024492 APE_0682a.1 d762dc5209d270aefd007a56ad476ede 68 Pfam PF10049 Protein of unknown function (DUF2283) 16 63 2.0E-12 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 APE_0187 9a42fba73221548bd7145549a9f26ccc 188 Pfam PF05916 GINS complex protein 47 159 2.2E-8 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 APE_2497 80b0a9ef3da36a87f1b2f2e59e815d07 199 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 5 190 9.7E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 APE_2497 80b0a9ef3da36a87f1b2f2e59e815d07 199 Pfam PF01914 MarC family integral membrane protein 7 193 5.6E-32 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 APE_2207.1 d0d916f7a4b136df153a50cf54a9cce9 332 Pfam PF00482 Type II secretion system (T2SS), protein F 145 272 2.4E-14 T 23-10-2018 IPR018076 Type II secretion system F domain APE_1561 08e093ae57143c31cead7303bf05f12c 138 PIRSF PIRSF014405 1 134 3.2E-60 T 23-10-2018 IPR012372 Uncharacterised conserved protein UCP014405, metallopeptidase Zn-binding site APE_0939 5b6a1f9f09c41b17d6529ef273d3bc5b 100 Hamap MF_01245 UPF0248 protein . 12 85 19.037 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 APE_0939 5b6a1f9f09c41b17d6529ef273d3bc5b 100 Pfam PF04457 Protein of unknown function (DUF504) 28 84 1.3E-12 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 APE_0067.1 89f48a7a74bc3a19c44457308dcc5c56 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 255 1.7E-34 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_0065 33595f5577b785cd3713117b4c1c9b08 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 302 1.6E-18 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_0748.1 56e01e50ee132294300b016fec6e2880 362 Pfam PF04981 NMD3 family 5 241 2.8E-43 T 23-10-2018 IPR007064 Nmd3, N-terminal APE_1907 0d287caeac3e29e5538a7afb0ccb0d92 246 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 4 27 2.9E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal APE_1907 0d287caeac3e29e5538a7afb0ccb0d92 246 Pfam PF01917 Archaebacterial flagellin 6 216 6.1E-30 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 APE_0256 e6e0e39758af792a5dfbcd0514612a40 185 PIRSF PIRSF006533 6 178 8.6E-51 T 23-10-2018 IPR007164 Protein of unknown function DUF359 APE_0256 e6e0e39758af792a5dfbcd0514612a40 185 Pfam PF04019 Protein of unknown function (DUF359) 59 158 1.3E-22 T 23-10-2018 IPR007164 Protein of unknown function DUF359 APE_0256 e6e0e39758af792a5dfbcd0514612a40 185 Hamap MF_00590 UPF0218 protein . 12 176 18.816 T 23-10-2018 IPR007164 Protein of unknown function DUF359 APE_1979.1 41ebc0c1f99e3e3761b33ff16cb351d3 138 Pfam PF01883 Iron-sulfur cluster assembly protein 20 97 5.0E-21 T 23-10-2018 IPR002744 MIP18 family-like APE_1979.1 41ebc0c1f99e3e3761b33ff16cb351d3 138 Gene3D G3DSA:3.30.300.130 13 118 1.2E-33 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APE_1979.1 41ebc0c1f99e3e3761b33ff16cb351d3 138 SUPERFAMILY SSF117916 20 116 5.89E-25 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily APE_0922 ff058d61ce19c5200bd1efd44d91af7b 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 326 7.9E-33 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 APE_1629a.1 4eb83b5cb5fcea281cb13bf7f6696b4a 73 SUPERFAMILY SSF63393 21 61 1.86E-5 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 APE_1629a.1 4eb83b5cb5fcea281cb13bf7f6696b4a 73 Gene3D G3DSA:2.20.28.30 21 73 9.4E-9 T 23-10-2018 APE_1990 39defb81bd505e267e7a8702f64ee03b 111 Gene3D G3DSA:3.40.30.10 13 79 6.2E-6 T 23-10-2018 APE_1478.1 6fbccc472aedabd579ca119ca564ecc7 221 Pfam PF04087 Domain of unknown function (DUF389) 68 206 1.2E-23 T 23-10-2018 IPR005240 Protein of unknown function DUF389 APE_1827.1 d2d8ca2cd6ff3b8fc61ff341bbc87a37 274 Pfam PF01061 ABC-2 type transporter 12 224 2.9E-8 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 APE_1689 36cd026045658f7258b1c58ad2d78f6b 163 PIRSF PIRSF014422 3 163 2.5E-69 T 23-10-2018 IPR016618 Uncharacterised conserved protein UCP014422 APE_2274 8dbacee02a3379a54a125ce604cb1099 999 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 77 103 2.7E-9 T 23-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_2274 8dbacee02a3379a54a125ce604cb1099 999 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 192 218 2.7E-9 T 23-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_2274 8dbacee02a3379a54a125ce604cb1099 999 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 285 304 2.7E-9 T 23-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_2274 8dbacee02a3379a54a125ce604cb1099 999 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 226 246 2.7E-9 T 23-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 APE_2274 8dbacee02a3379a54a125ce604cb1099 999 Pfam PF01578 Cytochrome C assembly protein 92 266 7.1E-14 T 23-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 APE_0843.1 0841cbd4576b9b542747398bca204a74 926 SUPERFAMILY SSF48208 472 706 6.8E-17 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 APE_2381.1 fbaeae09355af3aa50a3c8456e2f9998 409 Pfam PF02667 Short chain fatty acid transporter 11 408 5.3E-114 T 23-10-2018 IPR006160 Short chain fatty acid transporter AtoE APE_0470.1 802d114befe8061220748523031b2fb8 254 Pfam PF12679 ABC-2 family transporter protein 54 250 6.1E-10 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 APE_0472b.1 b3f648f4b6a17820178061733456f709 61 SUPERFAMILY SSF141694 3 54 2.33E-5 T 23-10-2018 APE_0472b.1 b3f648f4b6a17820178061733456f709 61 Pfam PF01954 Protein of unknown function DUF104 1 47 7.5E-6 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 APE_1649.1 73e55775cb677d1ab0ca275609206cd1 427 Gene3D G3DSA:3.40.50.300 85 285 5.0E-20 T 23-10-2018 APE_1649.1 73e55775cb677d1ab0ca275609206cd1 427 SUPERFAMILY SSF52540 78 237 2.97E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase APE_1649.1 73e55775cb677d1ab0ca275609206cd1 427 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 104 279 1.3E-28 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain APE_0614.1 b7d23efe949e3158724d6b2a530ea79b 541 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 6.4E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal APE_1599.1 38853f1494ac92338bd7af00cb031a33 667 Pfam PF04312 Protein of unknown function (DUF460) 225 360 1.0E-43 T 23-10-2018 IPR007408 Protein of unknown function DUF460 APE_0469.1 1550805532d1b54e2bb7c04580e619d6 136 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 32 103 2.9E-21 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative APE_0469.1 1550805532d1b54e2bb7c04580e619d6 136 Gene3D G3DSA:1.10.10.60 57 86 1.8E-5 T 23-10-2018 APE_0821 74630c9d36ab4ca6df1ad20325fdef2e 326 SUPERFAMILY SSF46785 132 195 1.94E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily APE_1209f 0a9ea5f4e006c1c2799a990bd679dba7 32 SUPERFAMILY SSF47203 2 30 8.54E-6 T 23-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114