locus-tag	class	description
OCA4_c00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OCA4_c00030	COG2852	Protein conserved in bacteria
OCA4_c00040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OCA4_c00060	COG1741	Belongs to the pirin family
OCA4_c00090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCA4_c00100	COG0728	peptidoglycan biosynthetic process
OCA4_c00110	COG0180	Tryptophanyl-tRNA synthetase
OCA4_c00120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OCA4_c00130	COG1214	PFAM Peptidase M22, glycoprotease
OCA4_c00140	COG0456	acetyltransferase
OCA4_c00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCA4_c00170	COG1702	phosphate starvation-inducible protein PhoH
OCA4_c00180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OCA4_c00190	COG1253	flavin adenine dinucleotide binding
OCA4_c00200	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OCA4_c00210	COG1396	sequence-specific DNA binding
OCA4_c00220	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OCA4_c00240	COG0779	Required for maturation of 30S ribosomal subunits
OCA4_c00270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OCA4_c00280	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OCA4_c00290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OCA4_c00300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OCA4_c00310	COG1185	polyribonucleotide nucleotidyltransferase activity
OCA4_c00330	COG0583	DNA-binding transcription factor activity
OCA4_c00350	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCA4_c00370	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCA4_c00410	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCA4_c00420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OCA4_c00430	COG2226	methyltransferase
OCA4_c00440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OCA4_c00450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OCA4_c00460	COG0756	dUTP diphosphatase activity
OCA4_c00470	COG2205	protein histidine kinase activity
OCA4_c00480	COG3178	'Phosphotransferase
OCA4_c00500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCA4_c00520	COG1074	ATP-dependent DNA helicase activity
OCA4_c00550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OCA4_c00560	COG0159	tryptophan synthase activity
OCA4_c00570	COG0133	tryptophan synthase activity
OCA4_c00580	COG0135	phosphoribosylanthranilate isomerase activity
OCA4_c00600	COG0776	regulation of translation
OCA4_c00610	COG0616	signal peptide processing
OCA4_c00620	COG0539	negative regulation of cytoplasmic translation
OCA4_c00630	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OCA4_c00660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OCA4_c00690	COG0071	Belongs to the small heat shock protein (HSP20) family
OCA4_c00710	COG0129	dihydroxy-acid dehydratase activity
OCA4_c00720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCA4_c00730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OCA4_c00740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OCA4_c00750	COG1137	ATPase activity
OCA4_c00760	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OCA4_c00780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCA4_c00790	COG0058	SHG alpha-glucan phosphorylase activity
OCA4_c00820	COG5001	Diguanylate cyclase
OCA4_c00820	COG3447	MASE1 domain protein
OCA4_c00820	COG5002	protein histidine kinase activity
OCA4_c00850	COG1968	undecaprenyl-diphosphatase activity
OCA4_c00890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OCA4_c00900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OCA4_c00910	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OCA4_c00920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OCA4_c00930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCA4_c00930	COG0072	phenylalanine-tRNA ligase activity
OCA4_c00960	COG0583	DNA-binding transcription factor activity
OCA4_c00970	COG0747	negative chemotaxis
OCA4_c00990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCA4_c01010	COG2267	carboxylic ester hydrolase activity
OCA4_c01050	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OCA4_c01080	COG0588	phosphoglycerate mutase activity
OCA4_c01090	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OCA4_c01100	COG0284	orotidine-5'-phosphate decarboxylase activity
OCA4_c01120	COG3963	phosphatidate phosphatase activity
OCA4_c01140	COG0443	Heat shock 70 kDa protein
OCA4_c01160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OCA4_c01170	COG1420	regulation of RNA biosynthetic process
OCA4_c01180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCA4_c01190	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OCA4_c01200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OCA4_c01220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OCA4_c01230	COG0792	nuclease activity
OCA4_c01240	COG0189	ligase activity
OCA4_c01300	COG1072	(Pantothenic acid kinase))
OCA4_c01310	COG0140	phosphoribosyl-ATP diphosphatase activity
OCA4_c01320	COG0107	imidazoleglycerol-phosphate synthase activity
OCA4_c01330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OCA4_c01340	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OCA4_c01360	COG0131	Imidazoleglycerol-phosphate dehydratase
OCA4_c01370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OCA4_c01380	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OCA4_c01400	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OCA4_c01420	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OCA4_c01430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCA4_c01440	COG0237	dephospho-CoA kinase activity
OCA4_c01450	COG0424	maF-like protein
OCA4_c01460	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OCA4_c01470	COG1981	membrane
OCA4_c01480	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OCA4_c01490	COG1396	sequence-specific DNA binding
OCA4_c01510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCA4_c01550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OCA4_c01560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c01570	COG1331	Highly conserved protein containing a thioredoxin domain
OCA4_c01580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OCA4_c01590	COG0445	tRNA wobble uridine modification
OCA4_c01600	COG0357	Ribosomal RNA small subunit methyltransferase G
OCA4_c01660	COG0495	leucyl-tRNA aminoacylation
OCA4_c01670	COG2203	Gaf domain
OCA4_c01670	COG5001	Diguanylate cyclase
OCA4_c01670	COG4251	negative regulation of phosphorylation
OCA4_c01670	COG3706	GGDEF domain
OCA4_c01680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OCA4_c01700	COG0745	RESPONSE REGULATOR receiver
OCA4_c01710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCA4_c01740	COG1674	ftsk spoiiie
OCA4_c01750	COG0436	Aminotransferase
OCA4_c01760	COG0004	ammonium transporteR
OCA4_c01770	COG0347	Belongs to the P(II) protein family
OCA4_c01780	COG1946	Acyl-CoA thioesterase
OCA4_c01790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCA4_c01800	COG2835	tetraacyldisaccharide 4'-kinase activity
OCA4_c01820	COG3118	belongs to the thioredoxin family
OCA4_c01850	COG0432	Pfam Uncharacterised protein family UPF0047
OCA4_c01880	COG0405	Gamma-glutamyltransferase
OCA4_c01900	COG0138	bifunctional purine biosynthesis protein purh
OCA4_c01940	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c01950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCA4_c01970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OCA4_c01980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OCA4_c02050	COG0583	DNA-binding transcription factor activity
OCA4_c02100	COG4221	oxidoreductase activity
OCA4_c02140	COG1872	DUF167
OCA4_c02150	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OCA4_c02160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OCA4_c02170	COG1247	-acetyltransferase
OCA4_c02190	COG1217	gtp-binding protein TYPA
OCA4_c02210	COG2154	pterin-4-alpha-carbinolamine dehydratase
OCA4_c02240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OCA4_c02260	COG0671	phosphoesterase, PA-phosphatase related
OCA4_c02270	COG0137	argininosuccinate synthase activity
OCA4_c02360	COG0318	PFAM AMP-dependent synthetase and ligase
OCA4_c02370	COG0477	Major facilitator Superfamily
OCA4_c02380	COG0473	3-isopropylmalate dehydrogenase activity
OCA4_c02400	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCA4_c02410	COG0288	reversible hydration of carbon dioxide
OCA4_c02420	COG2301	Belongs to the HpcH HpaI aldolase family
OCA4_c02430	COG0066	3-isopropylmalate dehydratase activity
OCA4_c02450	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OCA4_c02470	COG0335	large ribosomal subunit rRNA binding
OCA4_c02480	COG0336	Belongs to the RNA methyltransferase TrmD family
OCA4_c02490	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OCA4_c02500	COG0228	four-way junction DNA binding
OCA4_c02510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCA4_c02540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OCA4_c02550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCA4_c02560	COG0564	pseudouridine synthase activity
OCA4_c02570	COG0552	protein localization to endoplasmic reticulum
OCA4_c02580	COG2917	probably involved in intracellular septation
OCA4_c02600	COG4191	Histidine kinase
OCA4_c02610	COG1595	DNA-templated transcription, initiation
OCA4_c02650	COG3794	PFAM blue (type 1) copper domain protein
OCA4_c02760	COG2151	metal-sulfur cluster biosynthetic enzyme
OCA4_c02790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCA4_c02790	COG3453	Protein conserved in bacteria
OCA4_c02810	COG4974	Belongs to the 'phage' integrase family
OCA4_c02850	COG0798	PFAM Bile acid sodium symporter
OCA4_c02860	COG0431	NADPH-dependent FMN reductase
OCA4_c03050	COG5489	Protein of unknown function (DUF736)
OCA4_c03110	COG1192	Involved in chromosome partitioning
OCA4_c03160	COG0741	lytic transglycosylase activity
OCA4_c03210	COG4962	Type ii secretion system protein e
OCA4_c03230	COG3451	type IV secretory pathway VirB4
OCA4_c03260	COG3846	protein secretion by the type IV secretion system
OCA4_c03290	COG2948	multi-organism process
OCA4_c03310	COG0583	DNA-binding transcription factor activity
OCA4_c03330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCA4_c03350	COG2205	protein histidine kinase activity
OCA4_c03360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OCA4_c03370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OCA4_c03380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OCA4_c03470	COG0071	Belongs to the small heat shock protein (HSP20) family
OCA4_c03480	COG0071	Belongs to the small heat shock protein (HSP20) family
OCA4_c03490	COG3093	addiction module antidote protein HigA
OCA4_c03530	COG0210	DNA helicase
OCA4_c03710	COG1902	pentaerythritol trinitrate reductase activity
OCA4_c03720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCA4_c03760	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
OCA4_c03810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCA4_c03820	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OCA4_c03830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCA4_c03840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c03880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OCA4_c03900	COG0735	belongs to the Fur family
OCA4_c03910	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OCA4_c03940	COG0142	geranyltranstransferase activity
OCA4_c03950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OCA4_c03960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OCA4_c03990	COG5001	Diguanylate cyclase
OCA4_c03990	COG3300	MHYT domain
OCA4_c04010	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
OCA4_c04050	COG0154	amidase activity
OCA4_c04070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCA4_c04100	COG2890	protein-(glutamine-N5) methyltransferase activity
OCA4_c04110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OCA4_c04120	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
OCA4_c04140	COG0527	aspartate kinase activity
OCA4_c04160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCA4_c04190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCA4_c04200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCA4_c04210	COG1040	competence protein
OCA4_c04220	COG2226	methyltransferase
OCA4_c04230	COG0494	nUDIX hydrolase
OCA4_c04240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OCA4_c04250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCA4_c04260	COG0653	protein targeting
OCA4_c04280	COG3034	peptidoglycan biosynthetic process
OCA4_c04290	COG0825	malonyl-CoA metabolic process
OCA4_c04300	COG4974	Belongs to the 'phage' integrase family
OCA4_c04320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OCA4_c04330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OCA4_c04340	COG4536	flavin adenine dinucleotide binding
OCA4_c04420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OCA4_c04570	COG0069	glutamate synthase activity
OCA4_c04580	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OCA4_c04610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCA4_c04630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c04640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCA4_c04660	COG2003	Belongs to the UPF0758 family
OCA4_c04750	COG0640	Transcriptional regulator
OCA4_c04780	COG0798	PFAM Bile acid sodium symporter
OCA4_c04790	COG0431	NADPH-dependent FMN reductase
OCA4_c04830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCA4_c04850	COG0789	Transcriptional regulator
OCA4_c04890	COG0793	Belongs to the peptidase S41A family
OCA4_c04900	COG5489	Protein of unknown function (DUF736)
OCA4_c05020	COG0741	lytic transglycosylase activity
OCA4_c05050	COG1937	Protein conserved in bacteria
OCA4_c05140	COG1214	PFAM Peptidase M22, glycoprotease
OCA4_c05140	COG0456	acetyltransferase
OCA4_c05170	COG2372	response to copper ion
OCA4_c05240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCA4_c05290	COG1595	DNA-templated transcription, initiation
OCA4_c05310	COG0583	DNA-binding transcription factor activity
OCA4_c05340	COG4962	Type ii secretion system protein e
OCA4_c05370	COG3451	type IV secretory pathway VirB4
OCA4_c05400	COG3846	protein secretion by the type IV secretion system
OCA4_c05410	COG3701	Conjugal transfer protein
OCA4_c05470	COG2003	Belongs to the UPF0758 family
OCA4_c05480	COG0024	Methionine aminopeptidase
OCA4_c05490	COG1511	domain protein
OCA4_c05490	COG3264	Mechanosensitive ion channel
OCA4_c05500	COG3263	regulation of cellular component size
OCA4_c05510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCA4_c05520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCA4_c05540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OCA4_c05550	COG4149	molybdate abc transporter
OCA4_c05560	COG0725	ABC transporter, periplasmic molybdate-binding protein
OCA4_c05600	COG3422	double-strand break repair
OCA4_c05620	COG0481	GTPase activity
OCA4_c05630	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCA4_c05640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCA4_c05640	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCA4_c05660	COG0642	Histidine kinase
OCA4_c05670	COG0745	RESPONSE REGULATOR receiver
OCA4_c05690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OCA4_c05730	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OCA4_c05740	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCA4_c05740	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCA4_c05760	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OCA4_c05770	COG1643	Atp-dependent helicase
OCA4_c05800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCA4_c05810	COG2188	Transcriptional regulator
OCA4_c05870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCA4_c05880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
OCA4_c05900	COG2855	membrane
OCA4_c05910	COG1522	sequence-specific DNA binding
OCA4_c05920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCA4_c05940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OCA4_c05950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OCA4_c05960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OCA4_c05970	COG2223	nitrite transmembrane transporter activity
OCA4_c05990	COG0242	peptide deformylase activity
OCA4_c06000	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OCA4_c06010	COG0101	tRNA pseudouridine synthase activity
OCA4_c06030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCA4_c06040	COG2171	N-acyltransferase activity
OCA4_c06060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCA4_c06080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OCA4_c06090	COG0706	membrane insertase activity
OCA4_c06100	COG0594	ribonuclease P activity
OCA4_c06110	COG3852	Histidine kinase
OCA4_c06150	COG0747	negative chemotaxis
OCA4_c06170	COG0789	Transcriptional regulator
OCA4_c06180	COG2217	Heavy metal translocating P-type atpase
OCA4_c06200	COG0154	amidase activity
OCA4_c06230	COG0601	transmembrane transport
OCA4_c06250	COG0444	Belongs to the ABC transporter superfamily
OCA4_c06260	COG4608	Belongs to the ABC transporter superfamily
OCA4_c06280	COG2080	2 iron, 2 sulfur cluster binding
OCA4_c06290	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCA4_c06290	COG2010	Cytochrome c
OCA4_c06310	COG5001	Diguanylate cyclase
OCA4_c06350	COG1414	Transcriptional regulator
OCA4_c06420	COG4585	Histidine kinase
OCA4_c06430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCA4_c06440	COG1132	(ABC) transporter
OCA4_c06460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCA4_c06460	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OCA4_c06510	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c06570	COG0583	DNA-binding transcription factor activity
OCA4_c06630	COG0154	amidase activity
OCA4_c06700	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCA4_c06710	COG1704	LemA family
OCA4_c06870	COG0582	viral genome integration into host DNA
OCA4_c06890	COG0183	Belongs to the thiolase family
OCA4_c06900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OCA4_c06930	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OCA4_c06940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OCA4_c06960	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OCA4_c06970	COG3474	cytochrome
OCA4_c06980	COG4166	transmembrane transport
OCA4_c06990	COG4166	transmembrane transport
OCA4_c07000	COG4174	ABC transporter (Permease)
OCA4_c07010	COG4239	(ABC) transporter, permease
OCA4_c07020	COG4172	Belongs to the ABC transporter superfamily
OCA4_c07030	COG0791	NLP P60 protein
OCA4_c07040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCA4_c07110	COG4964	Belongs to the GSP D family
OCA4_c07160	COG1278	Cold shock
OCA4_c07170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OCA4_c07180	COG0513	Belongs to the DEAD box helicase family
OCA4_c07210	COG0784	Response regulator, receiver
OCA4_c07250	COG0628	permease
OCA4_c07260	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c07280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OCA4_c07300	COG0175	sulfate reduction
OCA4_c07320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCA4_c07320	COG1648	precorrin-2 dehydrogenase activity
OCA4_c07330	COG0175	sulfate reduction
OCA4_c07340	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OCA4_c07350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OCA4_c07360	COG4208	sulfate ABC transporter
OCA4_c07370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OCA4_c07390	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c07420	COG0318	PFAM AMP-dependent synthetase and ligase
OCA4_c07440	COG1132	(ABC) transporter
OCA4_c07450	COG0140	phosphoribosyl-ATP diphosphatase activity
OCA4_c07460	COG1238	metal cluster binding
OCA4_c07480	COG3706	GGDEF domain
OCA4_c07510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCA4_c07540	COG1802	Transcriptional regulator
OCA4_c07550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCA4_c07570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c07580	COG4336	lyase activity
OCA4_c07590	COG0405	Gamma-glutamyltransferase
OCA4_c07600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OCA4_c07610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCA4_c07620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OCA4_c07640	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c07640	COG3321	synthase
OCA4_c07640	COG0604	alcohol dehydrogenase
OCA4_c07780	COG2358	TRAP transporter, solute receptor (TAXI family
OCA4_c07840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCA4_c07840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCA4_c07860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCA4_c07870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OCA4_c07880	COG0328	RNA-DNA hybrid ribonuclease activity
OCA4_c07910	COG1678	Uncharacterized ACR, COG1678
OCA4_c07920	COG5001	Diguanylate cyclase
OCA4_c07920	COG3300	MHYT domain
OCA4_c07930	COG3321	synthase
OCA4_c07930	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c07930	COG0604	alcohol dehydrogenase
OCA4_c07950	COG0254	rRNA binding
OCA4_c07960	COG1132	(ABC) transporter
OCA4_c08000	COG0483	inositol monophosphate 1-phosphatase activity
OCA4_c08030	COG3588	fructose-bisphosphate aldolase
OCA4_c08040	COG0126	phosphoglycerate kinase activity
OCA4_c08080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OCA4_c08090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OCA4_c08100	COG1692	metallophosphoesterase
OCA4_c08110	COG0217	transcriptional regulatory protein
OCA4_c08120	COG2239	Acts as a magnesium transporter
OCA4_c08130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OCA4_c08140	COG0632	four-way junction helicase activity
OCA4_c08160	COG2255	four-way junction helicase activity
OCA4_c08180	COG0824	Thioesterase
OCA4_c08230	COG0848	biopolymer transport protein
OCA4_c08250	COG0823	Involved in the tonB-independent uptake of proteins
OCA4_c08260	COG2885	chlorophyll binding
OCA4_c08280	COG0037	tRNA processing
OCA4_c08290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCA4_c08310	COG1309	transcriptional regulator
OCA4_c08320	COG0277	FAD linked oxidase domain protein
OCA4_c08330	COG0277	FAD linked oxidase domain protein
OCA4_c08340	COG0247	lactate metabolic process
OCA4_c08370	COG4178	(ABC) transporter
OCA4_c08380	COG1620	l-lactate permease
OCA4_c08420	COG0459	protein refolding
OCA4_c08430	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCA4_c08470	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c08470	COG1388	LysM domain
OCA4_c08480	COG3416	Protein conserved in bacteria
OCA4_c08500	COG0463	Glycosyl transferase, family 2
OCA4_c08510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OCA4_c08520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OCA4_c08560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OCA4_c08580	COG0312	modulator of DNA gyrase
OCA4_c08590	COG1218	3'(2'),5'-bisphosphate nucleotidase
OCA4_c08620	COG1519	Transferase
OCA4_c08630	COG1663	tetraacyldisaccharide 4'-kinase activity
OCA4_c08660	COG1570	exodeoxyribonuclease VII activity
OCA4_c08670	COG0151	Belongs to the GarS family
OCA4_c08690	COG0590	tRNA wobble adenosine to inosine editing
OCA4_c08700	COG1187	pseudouridine synthase activity
OCA4_c08710	COG0742	ribosomal rna small subunit methyltransferase
OCA4_c08720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OCA4_c08740	COG0612	Peptidase, M16
OCA4_c08750	COG0612	Peptidase, M16
OCA4_c08770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OCA4_c08780	COG4771	TonB-dependent receptor
OCA4_c08790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OCA4_c08800	COG0196	riboflavin kinase activity
OCA4_c08810	COG0745	RESPONSE REGULATOR receiver
OCA4_c08860	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OCA4_c08890	COG2852	Protein conserved in bacteria
OCA4_c08910	COG1942	4-Oxalocrotonate Tautomerase
OCA4_c08950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OCA4_c08960	COG1278	Cold shock
OCA4_c08970	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OCA4_c08980	COG0322	excinuclease ABC activity
OCA4_c08990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OCA4_c09010	COG0314	molybdopterin synthase activity
OCA4_c09020	COG2890	protein-(glutamine-N5) methyltransferase activity
OCA4_c09030	COG0590	tRNA wobble adenosine to inosine editing
OCA4_c09040	COG0534	Mate efflux family protein
OCA4_c09050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCA4_c09060	COG1846	Transcriptional regulator
OCA4_c09070	COG0745	RESPONSE REGULATOR receiver
OCA4_c09080	COG2205	protein histidine kinase activity
OCA4_c09110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OCA4_c09130	COG1496	oxidoreductase activity
OCA4_c09150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OCA4_c09180	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OCA4_c09190	COG0193	aminoacyl-tRNA hydrolase activity
OCA4_c09240	COG0488	(ABC) transporter
OCA4_c09250	COG0556	nucleotide-excision repair
OCA4_c09270	COG0625	glutathione transferase activity
OCA4_c09350	COG0436	Aminotransferase
OCA4_c09380	COG0659	secondary active sulfate transmembrane transporter activity
OCA4_c09390	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OCA4_c09410	COG1304	FMN binding
OCA4_c09420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCA4_c09430	COG2223	nitrite transmembrane transporter activity
OCA4_c09480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCA4_c09500	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCA4_c09520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OCA4_c09550	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCA4_c09560	COG0564	pseudouridine synthase activity
OCA4_c09620	COG2010	Cytochrome c
OCA4_c09650	COG3278	Belongs to the heme-copper respiratory oxidase family
OCA4_c09670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCA4_c09690	COG4566	intracellular signal transduction
OCA4_c09700	COG4191	Histidine kinase
OCA4_c09710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OCA4_c09730	COG0181	hydroxymethylbilane synthase activity
OCA4_c09740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OCA4_c09770	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c09830	COG0643	Histidine kinase
OCA4_c09830	COG0784	Response regulator, receiver
OCA4_c09830	COG2198	Histidine kinase
OCA4_c09850	COG0643	Histidine kinase
OCA4_c09850	COG2198	Histidine kinase
OCA4_c09850	COG0784	Response regulator, receiver
OCA4_c09860	COG2201	protein-glutamate methylesterase activity
OCA4_c09910	COG1595	DNA-templated transcription, initiation
OCA4_c09940	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OCA4_c09960	COG0840	transmembrane signaling receptor activity
OCA4_c10010	COG1802	Transcriptional regulator
OCA4_c10020	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c10030	COG1116	anion transmembrane transporter activity
OCA4_c10040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c10080	COG2205	protein histidine kinase activity
OCA4_c10090	COG4191	Histidine kinase
OCA4_c10090	COG0784	Response regulator, receiver
OCA4_c10140	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCA4_c10180	COG0438	transferase activity, transferring glycosyl groups
OCA4_c10190	COG2814	Major facilitator Superfamily
OCA4_c10200	COG0679	Auxin Efflux Carrier
OCA4_c10220	COG2079	MmgE PrpD family protein
OCA4_c10240	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OCA4_c10300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCA4_c10320	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCA4_c10330	COG0366	Alpha amylase catalytic
OCA4_c10340	COG0366	Alpha amylase catalytic
OCA4_c10350	COG1640	4-alpha-glucanotransferase
OCA4_c10360	COG0412	Dienelactone hydrolase
OCA4_c10400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCA4_c10430	COG2897	thiosulfate sulfurtransferase activity
OCA4_c10450	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c10460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OCA4_c10480	COG4106	trans-aconitate 2-methyltransferase activity
OCA4_c10570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCA4_c10590	COG2204	response regulator
OCA4_c10610	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OCA4_c10630	COG2022	thiamine diphosphate biosynthetic process
OCA4_c10770	COG0523	cobalamin synthesis protein
OCA4_c10780	COG4771	TonB-dependent receptor
OCA4_c10830	COG0714	Associated with various cellular activities
OCA4_c10850	COG0494	nUDIX hydrolase
OCA4_c10870	COG0617	tRNA 3'-terminal CCA addition
OCA4_c10900	COG0408	coproporphyrinogen oxidase activity
OCA4_c10920	COG0602	queuosine metabolic process
OCA4_c10930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OCA4_c10940	COG0723	plastoquinol--plastocyanin reductase activity
OCA4_c10950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OCA4_c10950	COG2857	Cytochrome c1
OCA4_c10980	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OCA4_c11020	COG1704	LemA family
OCA4_c11050	COG1196	nuclear chromosome segregation
OCA4_c11080	COG1194	a g-specific adenine glycosylase
OCA4_c11090	COG0625	glutathione transferase activity
OCA4_c11110	COG2189	Belongs to the N(4) N(6)-methyltransferase family
OCA4_c11120	COG2321	neutral zinc metallopeptidase
OCA4_c11130	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCA4_c11220	COG2814	Major facilitator Superfamily
OCA4_c11230	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c11240	COG1573	uracil-dna glycosylase
OCA4_c11280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OCA4_c11290	COG0142	geranyltranstransferase activity
OCA4_c11340	COG0752	glycyl-tRNA synthetase alpha subunit
OCA4_c11350	COG2852	Protein conserved in bacteria
OCA4_c11360	COG0751	glycine-tRNA ligase activity
OCA4_c11380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OCA4_c11380	COG0574	Belongs to the PEP-utilizing enzyme family
OCA4_c11410	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OCA4_c11420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OCA4_c11430	COG0604	alcohol dehydrogenase
OCA4_c11480	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OCA4_c11490	COG2818	Glycosylase
OCA4_c11500	COG0354	folic acid binding
OCA4_c11510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCA4_c11560	COG2135	peptidase activity
OCA4_c11570	COG0277	FAD linked oxidase domain protein
OCA4_c11580	COG0009	L-threonylcarbamoyladenylate synthase
OCA4_c11620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCA4_c11620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCA4_c11630	COG1960	acyl-CoA dehydrogenase activity
OCA4_c11680	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c11700	COG1324	tolerance protein
OCA4_c11720	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c11730	COG0259	pyridoxamine-phosphate oxidase activity
OCA4_c11750	COG0484	heat shock protein binding
OCA4_c11800	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCA4_c11810	COG0406	alpha-ribazole phosphatase activity
OCA4_c11820	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OCA4_c11840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCA4_c11850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
OCA4_c11860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCA4_c11870	COG1722	exodeoxyribonuclease VII activity
OCA4_c11880	COG0123	including yeast histone deacetylase and acetoin utilization protein
OCA4_c11890	COG1024	Enoyl-CoA hydratase
OCA4_c11900	COG1960	acyl-CoA dehydrogenase activity
OCA4_c11930	COG5001	Diguanylate cyclase
OCA4_c11940	COG0519	Catalyzes the synthesis of GMP from XMP
OCA4_c11970	COG1309	transcriptional regulator
OCA4_c11990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c12000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCA4_c12040	COG3181	Tripartite tricarboxylate transporter family receptor
OCA4_c12080	COG3052	prosthetic group binding
OCA4_c12120	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OCA4_c12300	COG3842	ATPase activity
OCA4_c12340	COG1120	ATPase activity
OCA4_c12380	COG2201	protein-glutamate methylesterase activity
OCA4_c12400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCA4_c12420	COG0243	molybdopterin cofactor binding
OCA4_c12430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCA4_c12430	COG1648	precorrin-2 dehydrogenase activity
OCA4_c12450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCA4_c12450	COG3218	ABC-type transport auxiliary lipoprotein component
OCA4_c12460	COG1127	ABC transporter
OCA4_c12490	COG0071	Belongs to the small heat shock protein (HSP20) family
OCA4_c12510	COG0517	IMP dehydrogenase activity
OCA4_c12530	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
OCA4_c12540	COG1042	CoA-binding domain protein
OCA4_c12540	COG0045	succinate-CoA ligase (ADP-forming) activity
OCA4_c12540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCA4_c12670	COG0625	glutathione transferase activity
OCA4_c12690	COG0318	PFAM AMP-dependent synthetase and ligase
OCA4_c12730	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCA4_c12770	COG0583	DNA-binding transcription factor activity
OCA4_c12790	COG0463	Glycosyl transferase, family 2
OCA4_c12790	COG1216	Glycosyl transferase, family 2
OCA4_c12800	COG1414	Transcriptional regulator
OCA4_c12810	COG4948	Mandelate Racemase Muconate Lactonizing
OCA4_c12890	COG0625	glutathione transferase activity
OCA4_c12970	COG0318	PFAM AMP-dependent synthetase and ligase
OCA4_c12990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OCA4_c13000	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OCA4_c13010	COG3842	ATPase activity
OCA4_c13020	COG1176	ABC-type spermidine putrescine transport system, permease component I
OCA4_c13070	COG0437	4 iron, 4 sulfur cluster binding
OCA4_c13090	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCA4_c13180	COG3706	GGDEF domain
OCA4_c13190	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCA4_c13200	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCA4_c13200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OCA4_c13220	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OCA4_c13230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCA4_c13240	COG1414	Transcriptional regulator
OCA4_c13260	COG0477	Major facilitator Superfamily
OCA4_c13280	COG1414	Transcriptional regulator
OCA4_c13290	COG0028	Belongs to the TPP enzyme family
OCA4_c13300	COG0583	DNA-binding transcription factor activity
OCA4_c13310	COG3181	Tripartite tricarboxylate transporter family receptor
OCA4_c13340	COG1012	belongs to the aldehyde dehydrogenase family
OCA4_c13360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCA4_c13390	COG3300	MHYT domain
OCA4_c13390	COG5001	Diguanylate cyclase
OCA4_c13400	COG0667	Aldo Keto reductase
OCA4_c13420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OCA4_c13430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OCA4_c13440	COG0156	8-amino-7-oxononanoate synthase activity
OCA4_c13460	COG4774	siderophore transport
OCA4_c13470	COG3128	pkhd-type hydroxylase
OCA4_c13490	COG0848	biopolymer transport protein
OCA4_c13510	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OCA4_c13550	COG0746	molybdenum cofactor guanylyltransferase activity
OCA4_c13560	COG1763	Mo-molybdopterin cofactor biosynthetic process
OCA4_c13570	COG0303	'Molybdopterin
OCA4_c13650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OCA4_c13660	COG3383	formate dehydrogenase (NAD+) activity
OCA4_c13720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCA4_c13740	COG0247	lactate metabolic process
OCA4_c13740	COG0277	FAD linked oxidase domain protein
OCA4_c13760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCA4_c13780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OCA4_c13820	COG1309	transcriptional regulator
OCA4_c13840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCA4_c13890	COG0656	L-ascorbic acid biosynthetic process
OCA4_c13900	COG2900	Belongs to the SlyX family
OCA4_c13910	COG1054	Belongs to the UPF0176 family
OCA4_c13920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OCA4_c13940	COG1562	ergosterol biosynthetic process
OCA4_c13950	COG1562	ergosterol biosynthetic process
OCA4_c13960	COG1233	COG1233 Phytoene dehydrogenase and related
OCA4_c13970	COG1657	PFAM Prenyltransferase squalene oxidase
OCA4_c13980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OCA4_c14000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCA4_c14010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCA4_c14020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCA4_c14030	COG2409	Drug exporters of the RND superfamily
OCA4_c14080	COG1473	amidohydrolase
OCA4_c14120	COG0427	acetyl-CoA hydrolase
OCA4_c14210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCA4_c14230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OCA4_c14250	COG0433	COG0433 Predicted ATPase
OCA4_c14290	COG4957	zinc ion binding
OCA4_c14330	COG2166	iron-sulfur cluster assembly
OCA4_c14360	COG2205	protein histidine kinase activity
OCA4_c14440	COG0861	Integral membrane protein TerC family
OCA4_c14490	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCA4_c14500	COG2983	Belongs to the UPF0260 family
OCA4_c14510	COG0477	Major facilitator Superfamily
OCA4_c14570	COG4695	Portal protein
OCA4_c14860	COG4235	cytochrome complex assembly
OCA4_c14870	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OCA4_c14880	COG1138	Cytochrome C-type biogenesis protein
OCA4_c14890	COG3088	subunit of a heme lyase
OCA4_c14910	COG0745	RESPONSE REGULATOR receiver
OCA4_c14920	COG2205	protein histidine kinase activity
OCA4_c14930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OCA4_c14940	COG2205	protein histidine kinase activity
OCA4_c14940	COG2202	Pas domain
OCA4_c14950	COG0045	succinate-CoA ligase (ADP-forming) activity
OCA4_c14960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCA4_c14980	COG1414	Transcriptional regulator
OCA4_c14990	COG3960	tartronate-semialdehyde synthase activity
OCA4_c15000	COG3622	Belongs to the hyi family
OCA4_c15010	COG2084	Dehydrogenase
OCA4_c15020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCA4_c15040	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCA4_c15050	COG1802	Transcriptional regulator
OCA4_c15060	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCA4_c15070	COG0045	succinate-CoA ligase (ADP-forming) activity
OCA4_c15110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCA4_c15140	COG2832	Protein of unknown function (DUF454)
OCA4_c15160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCA4_c15190	COG2205	protein histidine kinase activity
OCA4_c15200	COG1285	pathogenesis
OCA4_c15210	COG0306	phosphate transporter
OCA4_c15220	COG1392	Phosphate transport regulator
OCA4_c15240	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCA4_c15250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
OCA4_c15260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
OCA4_c15280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCA4_c15300	COG0546	phosphoglycolate phosphatase activity
OCA4_c15310	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OCA4_c15350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCA4_c15360	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
OCA4_c15400	COG0215	cysteine-tRNA ligase activity
OCA4_c15420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCA4_c15440	COG5265	(ABC) transporter
OCA4_c15460	COG0688	phosphatidylethanolamine metabolic process
OCA4_c15470	COG1183	phosphatidylcholine synthase activity
OCA4_c15480	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OCA4_c15500	COG3158	transport of potassium into the cell
OCA4_c15550	COG0604	alcohol dehydrogenase
OCA4_c15550	COG3321	synthase
OCA4_c15560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCA4_c15570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCA4_c15580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCA4_c15590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCA4_c15650	COG4774	siderophore transport
OCA4_c15690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCA4_c15700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCA4_c15760	COG0583	DNA-binding transcription factor activity
OCA4_c15770	COG0488	(ABC) transporter
OCA4_c15780	COG1671	Belongs to the UPF0178 family
OCA4_c15800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OCA4_c15840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCA4_c15840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCA4_c15850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCA4_c15850	COG0519	Catalyzes the synthesis of GMP from XMP
OCA4_c15920	COG5489	Protein of unknown function (DUF736)
OCA4_c16020	COG5489	Protein of unknown function (DUF736)
OCA4_c16060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OCA4_c16190	COG4962	Type ii secretion system protein e
OCA4_c16210	COG3451	type IV secretory pathway VirB4
OCA4_c16260	COG2948	multi-organism process
OCA4_c16290	COG0464	growth
OCA4_c16470	COG0038	chloride channel
OCA4_c16490	COG1393	Belongs to the ArsC family
OCA4_c16560	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OCA4_c16580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OCA4_c16620	COG0300	oxidoreductase activity
OCA4_c16640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OCA4_c16650	COG1286	toxin biosynthetic process
OCA4_c16670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OCA4_c16680	COG0305	Participates in initiation and elongation during chromosome replication
OCA4_c16690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OCA4_c16700	COG0359	binds to the 23S rRNA
OCA4_c16720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OCA4_c16730	COG0360	Binds together with S18 to 16S ribosomal RNA
OCA4_c16740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OCA4_c16760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCA4_c16770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCA4_c16780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OCA4_c16790	COG1561	YicC-like family, N-terminal region
OCA4_c16800	COG0194	GDP metabolic process
OCA4_c16810	COG0477	Major facilitator Superfamily
OCA4_c16850	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OCA4_c16880	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OCA4_c16900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCA4_c16930	COG0488	(ABC) transporter
OCA4_c16950	COG0105	UTP biosynthetic process
OCA4_c16960	COG0861	Integral membrane protein TerC family
OCA4_c16970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OCA4_c16980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OCA4_c17010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OCA4_c17020	COG0248	Ppx GppA phosphatase
OCA4_c17040	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OCA4_c17050	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OCA4_c17060	COG0281	malic enzyme
OCA4_c17060	COG0280	phosphate acetyltransferase
OCA4_c17110	COG3045	CreA protein
OCA4_c17250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCA4_c17270	COG0303	'Molybdopterin
OCA4_c17280	COG0315	cyclic pyranopterin monophosphate synthase activity
OCA4_c17290	COG0134	indole-3-glycerol-phosphate synthase activity
OCA4_c17300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCA4_c17320	COG0149	triose-phosphate isomerase activity
OCA4_c17340	COG0504	CTP synthase activity
OCA4_c17380	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OCA4_c17410	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCA4_c17420	COG0148	phosphopyruvate hydratase activity
OCA4_c17430	COG0431	NADPH-dependent FMN reductase
OCA4_c17470	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OCA4_c17480	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCA4_c17480	COG0022	dehydrogenase e1 component
OCA4_c17490	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCA4_c17520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCA4_c17540	COG0129	dihydroxy-acid dehydratase activity
OCA4_c17560	COG0708	Exodeoxyribonuclease III
OCA4_c17570	COG0316	Belongs to the HesB IscA family
OCA4_c17580	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OCA4_c17590	COG0018	arginyl-trna synthetase
OCA4_c17610	COG1472	Belongs to the glycosyl hydrolase 3 family
OCA4_c17620	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OCA4_c17630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OCA4_c17650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCA4_c17660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCA4_c17670	COG0805	protein transport
OCA4_c17680	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OCA4_c17690	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OCA4_c17710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCA4_c17760	COG1862	Preprotein translocase
OCA4_c17770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCA4_c17810	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OCA4_c17830	COG0693	protein deglycase activity
OCA4_c17930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OCA4_c17950	COG0629	single-stranded DNA binding
OCA4_c17960	COG2095	MarC family integral membrane protein
OCA4_c17970	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OCA4_c17990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OCA4_c18020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OCA4_c18030	COG0343	queuine tRNA-ribosyltransferase activity
OCA4_c18060	COG0840	transmembrane signaling receptor activity
OCA4_c18140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OCA4_c18150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OCA4_c18210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OCA4_c18270	COG4774	siderophore transport
OCA4_c18280	COG3785	DNA binding
OCA4_c18290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCA4_c18300	COG1183	phosphatidylcholine synthase activity
OCA4_c18310	COG1253	flavin adenine dinucleotide binding
OCA4_c18330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCA4_c18340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OCA4_c18350	COG1984	allophanate hydrolase subunit 2
OCA4_c18360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OCA4_c18370	COG0473	3-isopropylmalate dehydrogenase activity
OCA4_c18370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCA4_c18430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OCA4_c18440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCA4_c18470	COG1177	transmembrane transport
OCA4_c18480	COG3842	ATPase activity
OCA4_c18490	COG2132	Multicopper oxidase
OCA4_c18550	COG0582	viral genome integration into host DNA
OCA4_c19000	COG1686	Belongs to the peptidase S11 family
OCA4_c19010	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OCA4_c19020	COG0470	DNA polymerase III
OCA4_c19040	COG0084	hydrolase, TatD family'
OCA4_c19050	COG0321	lipoyl(octanoyl) transferase activity
OCA4_c19050	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OCA4_c19060	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OCA4_c19130	COG0489	protein tyrosine kinase activity
OCA4_c19130	COG3206	protein involved in exopolysaccharide biosynthesis
OCA4_c19210	COG0438	transferase activity, transferring glycosyl groups
OCA4_c19230	COG2226	methyltransferase
OCA4_c19240	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OCA4_c19250	COG3956	TIGRFAM MazG family protein
OCA4_c19260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCA4_c19270	COG1923	regulation of RNA biosynthetic process
OCA4_c19280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCA4_c19290	COG2204	response regulator
OCA4_c19300	COG5000	phosphorelay sensor kinase activity
OCA4_c19340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OCA4_c19340	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OCA4_c19360	COG2867	negative regulation of translational initiation
OCA4_c19370	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OCA4_c19380	COG2094	Belongs to the DNA glycosylase MPG family
OCA4_c19390	COG0525	valine-tRNA ligase activity
OCA4_c19420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCA4_c19480	COG4172	Belongs to the ABC transporter superfamily
OCA4_c19490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCA4_c19520	COG0129	dihydroxy-acid dehydratase activity
OCA4_c19540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCA4_c19550	COG0583	DNA-binding transcription factor activity
OCA4_c19560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCA4_c19570	COG1960	acyl-CoA dehydrogenase activity
OCA4_c19580	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OCA4_c19590	COG1024	Enoyl-CoA hydratase
OCA4_c19640	COG1538	Outer membrane efflux protein
OCA4_c19660	COG1126	abc transporter atp-binding protein
OCA4_c19670	COG0765	amino acid transport
OCA4_c19680	COG4597	amino acid ABC transporter
OCA4_c19690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCA4_c19700	COG0626	cystathionine gamma-synthase activity
OCA4_c19720	COG0463	Glycosyl transferase, family 2
OCA4_c19730	COG0671	phosphoesterase, PA-phosphatase related
OCA4_c19740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OCA4_c19930	COG1278	Cold shock
OCA4_c20010	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OCA4_c20020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OCA4_c20030	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OCA4_c20040	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OCA4_c20070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCA4_c20080	COG1494	fructose-1,6-bisphosphatase
OCA4_c20100	COG0436	Aminotransferase
OCA4_c20120	COG3243	poly(R)-hydroxyalkanoic acid synthase
OCA4_c20140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OCA4_c20150	COG0586	Pfam SNARE associated Golgi protein
OCA4_c20160	COG0187	DNA topoisomerase II activity
OCA4_c20180	COG0513	Belongs to the DEAD box helicase family
OCA4_c20190	COG3706	GGDEF domain
OCA4_c20200	COG0316	Belongs to the HesB IscA family
OCA4_c20210	COG2151	metal-sulfur cluster biosynthetic enzyme
OCA4_c20220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCA4_c20230	COG0719	Fe-S assembly protein
OCA4_c20240	COG0396	ATPase activity
OCA4_c20250	COG0719	Fe-S assembly protein
OCA4_c20260	COG1104	cysteine desulfurase activity
OCA4_c20270	COG2945	thiolester hydrolase activity
OCA4_c20280	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OCA4_c20290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OCA4_c20310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OCA4_c20320	COG0739	heme binding
OCA4_c20340	COG0590	tRNA wobble adenosine to inosine editing
OCA4_c20360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCA4_c20370	COG0860	N-Acetylmuramoyl-L-alanine amidase
OCA4_c20380	COG1530	ribonuclease E activity
OCA4_c20380	COG1530	ribonuclease E activity
OCA4_c20390	COG0436	Aminotransferase
OCA4_c20420	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OCA4_c20430	COG0511	ligase activity, forming carbon-carbon bonds
OCA4_c20450	COG2205	protein histidine kinase activity
OCA4_c20460	COG0784	Response regulator, receiver
OCA4_c20470	COG0745	RESPONSE REGULATOR receiver
OCA4_c20480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OCA4_c20490	COG0658	competence protein
OCA4_c20490	COG2333	competence protein COMEC
OCA4_c20500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCA4_c20510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCA4_c20520	COG0372	Belongs to the citrate synthase family
OCA4_c20540	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCA4_c20550	COG3494	Protein of unknown function (DUF1009)
OCA4_c20560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCA4_c20570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCA4_c20580	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCA4_c20590	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCA4_c20600	COG0750	zinc metalloprotease
OCA4_c20610	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OCA4_c20630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OCA4_c20640	COG0233	cytoplasmic translational termination
OCA4_c20650	COG0528	UMP kinase activity
OCA4_c20660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OCA4_c20670	COG0052	Belongs to the universal ribosomal protein uS2 family
OCA4_c20720	COG1136	(ABC) transporter
OCA4_c20740	COG0442	prolyl-tRNA aminoacylation
OCA4_c20760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCA4_c20780	COG4774	siderophore transport
OCA4_c20780	COG4774	siderophore transport
OCA4_c20810	COG0346	lactoylglutathione lyase activity
OCA4_c20840	COG1007	ATP synthesis coupled electron transport
OCA4_c20870	COG0713	ATP synthesis coupled electron transport
OCA4_c20890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCA4_c20900	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OCA4_c20920	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OCA4_c20930	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
OCA4_c20940	COG0649	NAD binding
OCA4_c20960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCA4_c20970	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCA4_c20990	COG0473	3-isopropylmalate dehydrogenase activity
OCA4_c21000	COG0776	regulation of translation
OCA4_c21020	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCA4_c21050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCA4_c21080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OCA4_c21090	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OCA4_c21100	COG0740	serine-type endopeptidase activity
OCA4_c21110	COG0544	peptidyl-prolyl cis-trans isomerase activity
OCA4_c21140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OCA4_c21140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OCA4_c21150	COG0347	Belongs to the P(II) protein family
OCA4_c21160	COG0174	glutamine synthetase
OCA4_c21210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OCA4_c21220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OCA4_c21260	COG0672	)-iron permease
OCA4_c21270	COG1612	heme a metabolic process
OCA4_c21350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OCA4_c21380	COG2755	lipolytic protein G-D-S-L family
OCA4_c21380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OCA4_c21400	COG0776	regulation of translation
OCA4_c21410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCA4_c21420	COG0416	fatty acid biosynthetic process
OCA4_c21500	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
OCA4_c21510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OCA4_c21520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCA4_c21530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OCA4_c21550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCA4_c21550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCA4_c21560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OCA4_c21570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OCA4_c21620	COG0113	porphobilinogen synthase activity
OCA4_c21640	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OCA4_c21660	COG1914	H( )-stimulated, divalent metal cation uptake system
OCA4_c21680	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OCA4_c21700	COG1381	Involved in DNA repair and RecF pathway recombination
OCA4_c21730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OCA4_c21740	COG0571	ribonuclease III activity
OCA4_c21750	COG0681	Belongs to the peptidase S26 family
OCA4_c21760	COG0736	holo-[acyl-carrier-protein] synthase activity
OCA4_c21770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OCA4_c21790	COG1758	RNA polymerase activity
OCA4_c21830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OCA4_c21840	COG1970	mechanosensitive ion channel activity
OCA4_c21850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCA4_c21860	COG0741	lytic transglycosylase activity
OCA4_c21940	COG2963	transposase activity
OCA4_c21970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OCA4_c22050	COG1335	isochorismatase
OCA4_c22070	COG0583	DNA-binding transcription factor activity
OCA4_c22100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OCA4_c22140	COG0154	amidase activity
OCA4_c22160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OCA4_c22170	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OCA4_c22190	COG1960	acyl-CoA dehydrogenase activity
OCA4_c22200	COG0540	Belongs to the ATCase OTCase family
OCA4_c22210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCA4_c22220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OCA4_c22230	COG0758	DNA mediated transformation
OCA4_c22250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCA4_c22260	COG0557	exoribonuclease II activity
OCA4_c22300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OCA4_c22320	COG0784	Response regulator, receiver
OCA4_c22340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OCA4_c22420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OCA4_c22450	COG1686	Belongs to the peptidase S11 family
OCA4_c22480	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OCA4_c22580	COG0726	polysaccharide deacetylase
OCA4_c22610	COG0405	Gamma-glutamyltransferase
OCA4_c22630	COG2258	MOSC domain
OCA4_c22660	COG0321	lipoyl(octanoyl) transferase activity
OCA4_c22690	COG1254	Belongs to the acylphosphatase family
OCA4_c22710	COG0450	alkyl hydroperoxide reductase
OCA4_c22720	COG0415	Belongs to the DNA photolyase family
OCA4_c22730	COG0697	spore germination
OCA4_c22740	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OCA4_c22750	COG0596	Alpha beta hydrolase
OCA4_c22760	COG1764	response to oxidative stress
OCA4_c22770	COG1846	Transcriptional regulator
OCA4_c22820	COG0583	DNA-binding transcription factor activity
OCA4_c22830	COG1073	alpha beta
OCA4_c22840	COG1073	alpha beta
OCA4_c22850	COG0702	epimerase
OCA4_c22880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCA4_c22920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OCA4_c22960	COG0564	pseudouridine synthase activity
OCA4_c22970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OCA4_c22990	COG1733	regulation of RNA biosynthetic process
OCA4_c23020	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c23040	COG0203	ribosomal protein L17
OCA4_c23050	COG0202	RNA polymerase activity
OCA4_c23060	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OCA4_c23070	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OCA4_c23080	COG0563	adenylate kinase activity
OCA4_c23100	COG0200	Binds to the 23S rRNA
OCA4_c23110	COG1841	ribosomal large subunit assembly
OCA4_c23120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OCA4_c23130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OCA4_c23140	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OCA4_c23150	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OCA4_c23160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OCA4_c23170	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OCA4_c23180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OCA4_c23190	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OCA4_c23200	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OCA4_c23220	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OCA4_c23230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OCA4_c23240	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OCA4_c23250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OCA4_c23260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OCA4_c23270	COG0089	rRNA binding
OCA4_c23280	COG0088	Forms part of the polypeptide exit tunnel
OCA4_c23290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OCA4_c23300	COG0051	transcription antitermination factor activity, RNA binding
OCA4_c23310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCA4_c23320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCA4_c23330	COG0049	tRNA binding
OCA4_c23340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OCA4_c23380	COG1132	(ABC) transporter
OCA4_c23390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OCA4_c23400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OCA4_c23410	COG0085	RNA polymerase activity
OCA4_c23420	COG0222	ribosome binding
OCA4_c23430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OCA4_c23440	COG0081	regulation of translation
OCA4_c23450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OCA4_c23530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCA4_c23580	COG1414	Transcriptional regulator
OCA4_c23620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCA4_c23680	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
OCA4_c23700	COG4771	TonB-dependent receptor
OCA4_c23710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OCA4_c23720	COG2201	protein-glutamate methylesterase activity
OCA4_c23760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OCA4_c23770	COG0302	gtp cyclohydrolase
OCA4_c23800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OCA4_c23810	COG2080	2 iron, 2 sulfur cluster binding
OCA4_c23820	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
OCA4_c23830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OCA4_c23840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OCA4_c23870	COG1752	Esterase of the alpha-beta hydrolase superfamily
OCA4_c23880	COG0517	IMP dehydrogenase activity
OCA4_c24370	COG0305	Participates in initiation and elongation during chromosome replication
OCA4_c24540	COG0328	RNA-DNA hybrid ribonuclease activity
OCA4_c24550	COG0629	single-stranded DNA binding
OCA4_c24670	COG0859	PFAM glycosyl transferase family 9
OCA4_c24810	COG1064	alcohol dehydrogenase
OCA4_c24820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OCA4_c24830	COG1058	Belongs to the CinA family
OCA4_c24830	COG1546	Belongs to the CinA family
OCA4_c24850	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c24870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCA4_c24880	COG0459	protein refolding
OCA4_c24920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCA4_c24930	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
OCA4_c24960	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCA4_c25020	COG2068	MobA-Related Protein
OCA4_c25030	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OCA4_c25030	COG3608	succinylglutamate desuccinylase aspartoacylase
OCA4_c25050	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCA4_c25130	COG0785	Cytochrome C biogenesis protein
OCA4_c25140	COG3191	aminopeptidase activity
OCA4_c25240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OCA4_c25270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OCA4_c25280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OCA4_c25290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OCA4_c25300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OCA4_c25310	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
OCA4_c25340	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCA4_c25350	COG0047	phosphoribosylformylglycinamidine synthase activity
OCA4_c25360	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCA4_c25370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCA4_c25430	COG0538	isocitrate dehydrogenase activity
OCA4_c25450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCA4_c25450	COG4651	solute:proton antiporter activity
OCA4_c25470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCA4_c25480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OCA4_c25490	COG0509	glycine decarboxylation via glycine cleavage system
OCA4_c25500	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCA4_c25500	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCA4_c25510	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OCA4_c25520	COG1742	UPF0060 membrane protein
OCA4_c25530	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OCA4_c25630	COG2814	Major facilitator Superfamily
OCA4_c25690	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OCA4_c25690	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OCA4_c25770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OCA4_c25780	COG1684	flagellar biosynthetic protein fliR
OCA4_c25790	COG1987	bacterial-type flagellum assembly
OCA4_c25800	COG1677	Flagellar hook-basal body complex protein FliE
OCA4_c25810	COG1558	bacterial-type flagellum-dependent cell motility
OCA4_c25840	COG1338	Plays a role in the flagellum-specific transport system
OCA4_c25900	COG4786	Flagellar basal body rod
OCA4_c25910	COG4786	Flagellar basal body rod
OCA4_c25930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OCA4_c25970	COG1706	bacterial-type flagellum-dependent cell motility
OCA4_c26050	COG5443	negative regulation of bacterial-type flagellum assembly
OCA4_c26070	COG1256	bacterial-type flagellum assembly
OCA4_c26080	COG1749	Flagellar hook protein flgE
OCA4_c26150	COG3685	Protein conserved in bacteria
OCA4_c26160	COG0392	lysyltransferase activity
OCA4_c26180	COG0492	ferredoxin-NADP+ reductase activity
OCA4_c26190	COG0633	Ferredoxin
OCA4_c26220	COG0837	glucose binding
OCA4_c26230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCA4_c26230	COG3218	ABC-type transport auxiliary lipoprotein component
OCA4_c26240	COG1127	ABC transporter
OCA4_c26250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OCA4_c26260	COG4948	Mandelate Racemase Muconate Lactonizing
OCA4_c26290	COG0438	transferase activity, transferring glycosyl groups
OCA4_c26340	COG0728	peptidoglycan biosynthetic process
OCA4_c26360	COG0673	inositol 2-dehydrogenase activity
OCA4_c26400	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OCA4_c26400	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OCA4_c26430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCA4_c26440	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCA4_c26450	COG0859	PFAM glycosyl transferase family 9
OCA4_c26470	COG1132	(ABC) transporter
OCA4_c26480	COG0179	Fumarylacetoacetate (FAA) hydrolase
OCA4_c26520	COG1278	Cold shock
OCA4_c26530	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OCA4_c26540	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OCA4_c26600	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OCA4_c26670	COG0318	PFAM AMP-dependent synthetase and ligase
OCA4_c26710	COG0277	FAD linked oxidase domain protein
OCA4_c26720	COG2186	Transcriptional regulator
OCA4_c26780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCA4_c26790	COG2326	polyphosphate kinase activity
OCA4_c26800	COG1881	PFAM PEBP family protein
OCA4_c26810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OCA4_c26820	COG0440	acetolactate synthase activity
OCA4_c26830	COG0028	Belongs to the TPP enzyme family
OCA4_c26850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OCA4_c26880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OCA4_c26890	COG0560	Phosphoserine phosphatase
OCA4_c26890	COG3830	Belongs to the UPF0237 family
OCA4_c26920	COG0330	HflC and HflK could
OCA4_c26930	COG0330	HflC and HflK could
OCA4_c26950	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OCA4_c26970	COG0114	fumarate hydratase activity
OCA4_c27020	COG0277	FAD linked oxidase domain protein
OCA4_c27030	COG5487	UPF0391 membrane protein
OCA4_c27040	COG0210	DNA helicase
OCA4_c27050	COG1131	(ABC) transporter
OCA4_c27060	COG0842	Transport permease protein
OCA4_c27110	COG2264	protein methyltransferase activity
OCA4_c27130	COG0006	proline dipeptidase activity
OCA4_c27140	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OCA4_c27160	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCA4_c27180	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCA4_c27190	COG0849	cell division
OCA4_c27200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OCA4_c27210	COG1181	Belongs to the D-alanine--D-alanine ligase family
OCA4_c27230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OCA4_c27240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCA4_c27250	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OCA4_c27270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OCA4_c27290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCA4_c27310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OCA4_c27340	COG0275	rRNA processing
OCA4_c27390	COG1309	transcriptional regulator
OCA4_c27440	COG1024	Enoyl-CoA hydratase
OCA4_c27440	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCA4_c27470	COG3237	CsbD-like
OCA4_c27480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCA4_c27500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCA4_c27500	COG0512	Glutamine amidotransferase of anthranilate synthase
OCA4_c27510	COG2204	response regulator
OCA4_c27520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OCA4_c27540	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OCA4_c27550	COG1766	The M ring may be actively involved in energy transduction
OCA4_c27590	COG0482	sulfurtransferase activity
OCA4_c27630	COG1611	Belongs to the LOG family
OCA4_c27680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OCA4_c27680	COG2111	Na H antiporter
OCA4_c27690	COG1006	Multisubunit Na H antiporter MnhC subunit
OCA4_c27700	COG0651	ATP synthesis coupled electron transport
OCA4_c27720	COG2212	antiporter activity
OCA4_c27730	COG1320	monovalent cation:proton antiporter activity
OCA4_c27750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OCA4_c27760	COG2391	methyltransferase activity
OCA4_c27800	COG0737	Belongs to the 5'-nucleotidase family
OCA4_c27860	COG3258	Cytochrome c
OCA4_c27870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OCA4_c27880	COG0640	Transcriptional regulator
OCA4_c27910	COG0587	DNA-directed DNA polymerase activity
OCA4_c27940	COG1573	uracil-dna glycosylase
OCA4_c27950	COG1793	dna ligase
OCA4_c27970	COG1201	RNA secondary structure unwinding
OCA4_c28020	COG3276	selenocysteine insertion sequence binding
OCA4_c28050	COG1921	L-seryl-tRNASec selenium transferase activity
OCA4_c28070	COG2864	formate dehydrogenase
OCA4_c28080	COG0437	4 iron, 4 sulfur cluster binding
OCA4_c28100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCA4_c28110	COG1305	Transglutaminase-like
OCA4_c28140	COG1959	2 iron, 2 sulfur cluster binding
OCA4_c28160	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCA4_c28180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCA4_c28190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCA4_c28220	COG2951	lytic endotransglycosylase activity
OCA4_c28250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCA4_c28260	COG0358	DNA primase activity
OCA4_c28280	COG0640	Transcriptional regulator
OCA4_c28310	COG0505	Belongs to the CarA family
OCA4_c28340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OCA4_c28350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCA4_c28370	COG2259	Doxx family
OCA4_c28390	COG1522	sequence-specific DNA binding
OCA4_c28400	COG0492	ferredoxin-NADP+ reductase activity
OCA4_c28410	COG0583	DNA-binding transcription factor activity
OCA4_c28450	COG2205	protein histidine kinase activity
OCA4_c28460	COG1840	ABC-type Fe3 transport system, periplasmic component
OCA4_c28510	COG1177	transmembrane transport
OCA4_c28560	COG3842	ATPase activity
OCA4_c28570	COG3300	MHYT domain
OCA4_c28570	COG5001	Diguanylate cyclase
OCA4_c28630	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OCA4_c28640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCA4_c28650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OCA4_c28660	COG1012	belongs to the aldehyde dehydrogenase family
OCA4_c28760	COG1164	Oligoendopeptidase f
OCA4_c28770	COG2204	response regulator
OCA4_c28780	COG2989	Protein conserved in bacteria
OCA4_c28800	COG3750	Belongs to the UPF0335 family
OCA4_c28830	COG0469	pyruvate kinase activity
OCA4_c28850	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OCA4_c28860	COG0583	DNA-binding transcription factor activity
OCA4_c28870	COG1741	Belongs to the pirin family
OCA4_c28880	COG0655	NAD(P)H dehydrogenase (quinone) activity
OCA4_c28930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OCA4_c28940	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
OCA4_c28950	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OCA4_c28960	COG0363	glucosamine-6-phosphate deaminase activity
OCA4_c28970	COG3265	gluconokinase activity
OCA4_c28980	COG0561	phosphatase activity
OCA4_c28990	COG3387	PFAM Glycoside hydrolase 15-related
OCA4_c29000	COG1272	protein, Hemolysin III
OCA4_c29010	COG3106	COG3106 Predicted ATPase
OCA4_c29020	COG3768	UPF0283 membrane protein
OCA4_c29030	COG1278	Cold shock
OCA4_c29060	COG3023	N-Acetylmuramoyl-L-alanine amidase
OCA4_c29080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCA4_c29090	COG1120	ATPase activity
OCA4_c29100	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OCA4_c29110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCA4_c29120	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCA4_c29140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCA4_c29150	COG2181	nitrate reductase activity
OCA4_c29160	COG2963	transposase activity
OCA4_c29200	COG1024	Enoyl-CoA hydratase
OCA4_c29210	COG1414	Transcriptional regulator
OCA4_c29220	COG1012	belongs to the aldehyde dehydrogenase family
OCA4_c29330	COG2963	transposase activity
OCA4_c29570	COG0483	inositol monophosphate 1-phosphatase activity
OCA4_c29580	COG0583	DNA-binding transcription factor activity
OCA4_c29610	COG0071	Belongs to the small heat shock protein (HSP20) family
OCA4_c29620	COG1595	DNA-templated transcription, initiation
OCA4_c29650	COG0070	glutamate synthase
OCA4_c29650	COG0069	glutamate synthase activity
OCA4_c29650	COG0067	glutamate synthase
OCA4_c29690	COG2951	lytic endotransglycosylase activity
OCA4_c29700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OCA4_c29750	COG2203	Gaf domain
OCA4_c29750	COG4251	negative regulation of phosphorylation
OCA4_c29750	COG5001	Diguanylate cyclase
OCA4_c29750	COG3706	GGDEF domain
OCA4_c29800	COG0330	HflC and HflK could
OCA4_c29810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OCA4_c29820	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
OCA4_c29880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCA4_c29940	COG0523	cobalamin synthesis protein
OCA4_c29980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OCA4_c29990	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OCA4_c30110	COG4558	Periplasmic binding protein
OCA4_c30120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCA4_c30130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OCA4_c30150	COG2217	Heavy metal translocating P-type atpase
OCA4_c30160	COG2217	Heavy metal translocating P-type atpase
OCA4_c30190	COG1477	protein flavinylation
OCA4_c30230	COG3038	cytochrome b561
OCA4_c30320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCA4_c30330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCA4_c30350	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c30380	COG1309	transcriptional regulator
OCA4_c30400	COG1131	(ABC) transporter
OCA4_c30410	COG0842	Transport permease protein
OCA4_c30420	COG0842	Transport permease protein
OCA4_c30470	COG1136	(ABC) transporter
OCA4_c30470	COG0577	efflux transmembrane transporter activity
OCA4_c30490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCA4_c30500	COG1309	transcriptional regulator
OCA4_c30800	COG1475	DNA binding
OCA4_c31200	COG0739	heme binding
OCA4_c31210	COG0542	response to heat
OCA4_c31240	COG2813	Specifically methylates the guanine in position
OCA4_c31240	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCA4_c31250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OCA4_c31270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCA4_c31280	COG0287	Prephenate dehydrogenase
OCA4_c31340	COG2884	Cell division ATP-binding protein ftsE
OCA4_c31380	COG0019	diaminopimelate decarboxylase activity
OCA4_c31400	COG0165	Argininosuccinate lyase
OCA4_c31410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCA4_c31420	COG5507	3-demethylubiquinone-9 3-methyltransferase
OCA4_c31430	COG2764	glyoxalase bleomycin resistance protein dioxygenase
OCA4_c31440	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCA4_c31450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
OCA4_c31460	COG2086	electron transfer activity
OCA4_c31470	COG2096	Adenosyltransferase
OCA4_c31510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCA4_c31540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCA4_c31600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCA4_c31630	COG5001	Diguanylate cyclase
OCA4_c31650	COG0424	maF-like protein
OCA4_c31660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OCA4_c31670	COG5328	Belongs to the UPF0262 family
OCA4_c31680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OCA4_c31700	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OCA4_c31770	COG4774	siderophore transport
OCA4_c31790	COG1309	transcriptional regulator
OCA4_c31810	COG0697	spore germination
OCA4_c31820	COG1764	response to oxidative stress
OCA4_c31890	COG0235	Class ii aldolase
OCA4_c31910	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCA4_c31920	COG0156	8-amino-7-oxononanoate synthase activity
OCA4_c31930	COG4566	intracellular signal transduction
OCA4_c31940	COG0784	Response regulator, receiver
OCA4_c31940	COG2205	protein histidine kinase activity
OCA4_c31980	COG0356	it plays a direct role in the translocation of protons across the membrane
OCA4_c32000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCA4_c32010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCA4_c32040	COG0612	Peptidase, M16
OCA4_c32060	COG3346	SURF1 family
OCA4_c32080	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OCA4_c32100	COG0109	protoheme IX farnesyltransferase activity
OCA4_c32110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OCA4_c32120	COG1565	acr, cog1565
OCA4_c32120	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCA4_c32140	COG0312	modulator of DNA gyrase
OCA4_c32180	COG1846	Transcriptional regulator
OCA4_c32220	COG0534	Mate efflux family protein
OCA4_c32230	COG0167	dihydroorotate dehydrogenase activity
OCA4_c32280	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
OCA4_c32290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCA4_c32310	COG1999	signal sequence binding
OCA4_c32340	COG0717	Belongs to the dCTP deaminase family
OCA4_c32390	COG2967	ApaG domain
OCA4_c32410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OCA4_c32420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OCA4_c32440	COG0745	RESPONSE REGULATOR receiver
OCA4_c32450	COG0704	Plays a role in the regulation of phosphate uptake
OCA4_c32460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCA4_c32470	COG0581	inorganic phosphate transmembrane transporter activity
OCA4_c32480	COG0573	inorganic phosphate transmembrane transporter activity
OCA4_c32490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OCA4_c32500	COG5002	protein histidine kinase activity
OCA4_c32550	COG1271	oxidase subunit
OCA4_c32560	COG1294	oxidase, subunit
OCA4_c32580	COG1376	ErfK ybiS ycfS ynhG family protein
OCA4_c32590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCA4_c32600	COG2514	catechol 2,3-dioxygenase activity
OCA4_c32630	COG4948	Mandelate Racemase Muconate Lactonizing
OCA4_c32670	COG0402	S-adenosylhomocysteine deaminase activity
OCA4_c32680	COG0405	Gamma-glutamyltransferase
OCA4_c32690	COG2197	response regulator
OCA4_c32700	COG4585	Histidine kinase
OCA4_c32750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCA4_c32780	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OCA4_c32790	COG1877	trehalose-phosphatase activity
OCA4_c32800	COG0477	Major facilitator Superfamily
OCA4_c32820	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OCA4_c32830	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OCA4_c32840	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCA4_c32850	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCA4_c32860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OCA4_c32870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OCA4_c32880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OCA4_c32890	COG0799	negative regulation of ribosome biogenesis
OCA4_c32900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OCA4_c32920	COG0793	Belongs to the peptidase S41A family
OCA4_c32950	COG0494	nUDIX hydrolase
OCA4_c32960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCA4_c32970	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OCA4_c32980	COG1764	response to oxidative stress
OCA4_c32990	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OCA4_c33000	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OCA4_c33010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCA4_c33020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OCA4_c33050	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OCA4_c33070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCA4_c33080	COG1028	Short-chain dehydrogenase reductase Sdr
OCA4_c33090	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCA4_c33110	COG0039	L-malate dehydrogenase activity
OCA4_c33120	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OCA4_c33130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OCA4_c33150	COG4181	ATPase activity
OCA4_c33170	COG0670	Belongs to the BI1 family
OCA4_c33210	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OCA4_c33220	COG4133	protoheme IX ABC transporter activity
OCA4_c33230	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCA4_c33240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCA4_c33260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCA4_c33280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCA4_c33310	COG1120	ATPase activity
OCA4_c33320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCA4_c33340	COG1215	transferase activity, transferring glycosyl groups
OCA4_c33360	COG1132	(ABC) transporter
OCA4_c33390	COG1091	dTDP-4-dehydrorhamnose reductase activity
OCA4_c33430	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCA4_c33440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCA4_c33450	COG0784	Response regulator, receiver
OCA4_c33450	COG4191	Histidine kinase
OCA4_c33480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCA4_c33500	COG0268	Binds directly to 16S ribosomal RNA
OCA4_pHCG3B00010	COG1192	Involved in chromosome partitioning
OCA4_pHCG3B00020	COG1475	DNA binding
OCA4_pHCG3B00060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OCA4_pHCG3B00090	COG0546	phosphoglycolate phosphatase activity
OCA4_pHCG3B00160	COG2197	response regulator
OCA4_pHCG3B00170	COG3916	Acyl-homoserine-lactone synthase
OCA4_pHCG3B00220	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
OCA4_pHCG3B00230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCA4_pHCG3B00260	COG0587	DNA-directed DNA polymerase activity
OCA4_pHCG3B00340	COG3608	succinylglutamate desuccinylase aspartoacylase
OCA4_pHCG3B00340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OCA4_pHCG3B00380	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OCA4_pHCG3B00450	COG0126	phosphoglycerate kinase activity
OCA4_pHCG3B00480	COG4451	ribulose bisphosphate carboxylase, small
OCA4_pHCG3B00510	COG0546	phosphoglycolate phosphatase activity
OCA4_pHCG3B00530	COG2204	response regulator
OCA4_pHCG3B00540	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OCA4_pHCG3B00550	COG0375	protein maturation
OCA4_pHCG3B00600	COG0298	carbon dioxide binding
OCA4_pHCG3B00750	COG0864	Transcriptional regulator
OCA4_pHCG3B00810	COG2963	transposase activity
OCA4_pHCG3B00910	COG3547	Transposase (IS116 IS110 IS902 family)
OCA4_pHCG3B00980	COG0305	Participates in initiation and elongation during chromosome replication
OCA4_pHCG3B01000	COG5489	Protein of unknown function (DUF736)
OCA4_pHCG3B01010	COG3831	ATPase activity
OCA4_pHCG3B01030	COG3505	Type IV secretory pathway VirD4
OCA4_pHCG3B01060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCA4_pHCG3B01190	COG3701	Conjugal transfer protein
OCA4_pHCG3B01200	COG3846	protein secretion by the type IV secretion system
OCA4_pHCG3B01220	COG5314	conjugation
OCA4_pHCG3B01230	COG3451	type IV secretory pathway VirB4
OCA4_pHCG3B01240	COG5268	conjugation
OCA4_pHCG3B01250	COG3838	Conjugal transfer protein Trbc
OCA4_pHCG3B01260	COG4962	Type ii secretion system protein e
OCA4_pOC167B00010	COG1192	Involved in chromosome partitioning
OCA4_pOC167B00020	COG1475	DNA binding
OCA4_pOC167B00030	COG1414	Transcriptional regulator
OCA4_pOC167B00050	COG0629	single-stranded DNA binding
OCA4_pOC167B00080	COG1414	Transcriptional regulator
OCA4_pOC167B00100	COG1192	Involved in chromosome partitioning
OCA4_pOC167B00130	COG2197	response regulator
OCA4_pOC167B00150	COG1937	Protein conserved in bacteria
OCA4_pOC167B00240	COG0456	acetyltransferase
OCA4_pOC167B00240	COG1214	PFAM Peptidase M22, glycoprotease
OCA4_pOC167B00270	COG2372	response to copper ion
OCA4_pOC167B00360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCA4_pOC167B00410	COG1595	DNA-templated transcription, initiation
OCA4_pOC167B00540	COG2217	Heavy metal translocating P-type atpase
OCA4_pOC167B00600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OCA4_pOC167B00650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCA4_pOC167B00660	COG0431	NADPH-dependent FMN reductase
OCA4_pOC167B00680	COG0798	PFAM Bile acid sodium symporter
OCA4_pOC167B00710	COG0640	Transcriptional regulator
OCA4_pOC167B00800	COG2217	Heavy metal translocating P-type atpase
OCA4_pOC167B00940	COG0672	)-iron permease
OCA4_pOC167B00950	COG4786	Flagellar basal body rod
OCA4_pOC167B00960	COG1285	pathogenesis
OCA4_pOC167B01100	COG0697	spore germination
OCA4_pOC167B01120	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
OCA4_pOC167B01140	COG3504	Conjugal transfer protein
OCA4_pOC167B01160	COG3704	protein secretion by the type IV secretion system
OCA4_pOC167B01190	COG3451	type IV secretory pathway VirB4
OCA4_pOC167B01500	COG5489	Protein of unknown function (DUF736)
OCA4_pOC167B01610	COG0464	growth