locus-tag	class	description
ACT75_00005	ENOG4105CJ1	ABC, transporter
ACT75_00025	ENOG4105CD8	aminopeptidase N
ACT75_00030	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ACT75_00035	ENOG4105DB7	PHP domain protein
ACT75_00040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ACT75_00050	ENOG4105Q9Y	Universal stress protein
ACT75_00055	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
ACT75_00060	ENOG41090A1	ferritin
ACT75_00065	ENOG41090A1	ferritin
ACT75_00180	ENOG4105CJB	Exodeoxyribonuclease I
ACT75_00185	ENOG4108TZV	Membrane
ACT75_00190	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
ACT75_00195	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
ACT75_00200	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT75_00205	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
ACT75_00210	ENOG41061WM	D-Alanyl-D-Alanine
ACT75_00220	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ACT75_00225	ENOG4108VD1	dedA family
ACT75_00230	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
ACT75_00235	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ACT75_00245	ENOG4108ESZ	Glycogen debranching enzyme
ACT75_00250	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ACT75_00280	ENOG4105C5H	ABC transporter
ACT75_00285	ENOG4105VUH	addiction module killer protein
ACT75_00295	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
ACT75_00300	ENOG41067MG	lrgb family
ACT75_00305	ENOG4105VAW	lrga family
ACT75_00345	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
ACT75_00350	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ACT75_00355	ENOG4105CUW	cytochrome C-TYPE protein
ACT75_00360	ENOG4107QY8	reductase
ACT75_00365	ENOG4105UNS	Pfam:DUF419
ACT75_00370	ENOG4107QPK	)-transporter
ACT75_00385	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ACT75_00405	ENOG4107QYX	exodeoxyribonuclease v alpha
ACT75_00410	ENOG4107QKA	exodeoxyribonuclease V beta
ACT75_00415	ENOG41090EX	DsrE family
ACT75_00425	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
ACT75_00430	ENOG4105DAN	ATP-dependent protease
ACT75_00435	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
ACT75_00440	ENOG4105VEQ	Cold shock protein
ACT75_00445	ENOG4105X5C	UPF0181 protein
ACT75_00450	ENOG4105DR9	pseudouridine synthase
ACT75_00455	ENOG4105WP7	tRNA pseudouridine synthase C
ACT75_00460	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
ACT75_00470	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
ACT75_00490	ENOG4105DQ6	Transposase
ACT75_00495	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
ACT75_00510	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
ACT75_00515	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_00520	ENOG4108BPE	-transporting atpase
ACT75_00525	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACT75_00530	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
ACT75_00535	ENOG4105CIY	formyltetrahydrofolate deformylase
ACT75_00540	ENOG4108SAU	DNA-binding protein H-ns
ACT75_00545	ENOG4107S6Z	Na H antiporter
ACT75_00555	ENOG4108VTV	Inherit from NOG: Membrane
ACT75_00560	ENOG4105M4H	endoribonuclease L-psp
ACT75_00575	ENOG4107NA1	Endonuclease Exonuclease phosphatase
ACT75_00580	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ACT75_00590	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
ACT75_00595	ENOG4105EJ9	Membrane
ACT75_00600	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
ACT75_00605	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ACT75_00610	ENOG4105EGS	Mechanosensitive ion channel
ACT75_00615	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT75_00620	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
ACT75_00625	ENOG4105EV9	Alpha Beta Hydrolase
ACT75_00630	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ACT75_00635	ENOG41090R7	Ferric uptake
ACT75_00640	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT75_00650	ENOG4108ZJT	translation initiation factor, Sui1
ACT75_00660	ENOG4105CFV	Tetratricopeptide repeat protein
ACT75_00665	ENOG4105Q4A	inner membrane protein yciS
ACT75_00670	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ACT75_00675	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ACT75_00680	ENOG4105CAT	Cytidine monophosphate kinase
ACT75_00685	ENOG4108MJ5	VirK protein
ACT75_00690	ENOG4105PE1	Receptor
ACT75_00695	ENOG4107RAN	Peptidase, M16
ACT75_00700	ENOG4105KMT	branched-chain amino acid
ACT75_00705	ENOG4108UMN	azlc family
ACT75_00710	ENOG4105DZ2	Transcriptional regulator
ACT75_00715	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ACT75_00720	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
ACT75_00725	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ACT75_00760	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
ACT75_00770	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
ACT75_00775	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
ACT75_00780	ENOG4108535	NAD dependent epimerase/dehydratase family
ACT75_00785	ENOG4105CDH	Citrulline--aspartate ligase
ACT75_00790	ENOG4106CC8	Bacterial inner membrane protein
ACT75_00795	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ACT75_00805	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ACT75_00810	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
ACT75_00825	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
ACT75_00835	ENOG4105DHS	permease protein
ACT75_00840	ENOG4105CM4	permease protein
ACT75_00845	ENOG4108IPW	abc transporter atp-binding protein
ACT75_00850	ENOG4105DR5	peptidase
ACT75_00855	ENOG4105FDK	ABC transporter
ACT75_00860	ENOG4105FAV	ABC, transporter
ACT75_00865	ENOG4105C8J	)-transporter
ACT75_00870	ENOG4105CSM	endonuclease III
ACT75_00875	ENOG4105DZB	Electron transport complex
ACT75_00890	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
ACT75_00895	ENOG4108R3D	Electron transport complex
ACT75_00900	ENOG4105DGN	Electron transport complex
ACT75_00905	ENOG4105ECP	epimerase
ACT75_00910	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
ACT75_00915	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ACT75_00925	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ACT75_00930	ENOG4105ETT	transcriptional Regulator, LysR family
ACT75_00935	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
ACT75_00940	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
ACT75_00945	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACT75_00950	ENOG4105C0H	protease
ACT75_00955	ENOG4105DK2	UPF0207 protein
ACT75_00960	ENOG4105C8P	)-transporter
ACT75_00965	ENOG4105F4R	Transcriptional regulator mode
ACT75_00970	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ACT75_00975	ENOG4105E0C	molybdate abc transporter
ACT75_00980	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
ACT75_00990	ENOG4108M8S	permease YjgP YjgQ family protein
ACT75_00995	ENOG4108K5H	permease YjgP YjgQ family protein
ACT75_01000	ENOG4105SYT	Methylenetetrahydrofolate reductase
ACT75_01005	ENOG4105F9E	Shikimate 5-dehydrogenase
ACT75_01035	ENOG4105C45	hydrogenase expression formation protein (HypE)
ACT75_01040	ENOG4105CQS	hydrogenase expression formation protein HypD
ACT75_01045	ENOG4107RSS	Hydrogenase accessory protein HypB
ACT75_01050	ENOG4108JJB	ABC transporter
ACT75_01060	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
ACT75_01065	ENOG4108A51	
ACT75_01070	ENOG4105UZ0	ABC-type Co2 transport system, periplasmic component
ACT75_01075	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ACT75_01085	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ACT75_01090	ENOG4105T95	Thiol disulfide interChange protein
ACT75_01100	ENOG4105CRK	lysyL-tRNA synthetase
ACT75_01115	ENOG4105CXY	transporter
ACT75_01120	ENOG4105ECY	inositol monophosphatase
ACT75_01125	ENOG4105DH8	myo-inositol catabolism
ACT75_01145	ENOG4105CS6	Rhs element vgr protein
ACT75_01150	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
ACT75_01155	ENOG4107GZ4	SanA protein
ACT75_01160	ENOG4105DWV	Homoserine O-trans-acetylase
ACT75_01165	ENOG4105ETE	Transcriptional regulator (LacI family
ACT75_01170	ENOG4105XW2	UPF0263 protein
ACT75_01175	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
ACT75_01180	ENOG4107R11	Transcriptional regulator
ACT75_01185	ENOG4105FE9	pseudouridine synthase
ACT75_01190	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
ACT75_01195	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
ACT75_01200	ENOG4105D07	Signal peptide peptidase, SppA
ACT75_01205	ENOG41069NU	Nitroreductase
ACT75_01210	ENOG4107QN2	dihydrolipoyl dehydrogenase
ACT75_01215	ENOG4107QSN	dihydrolipoamide acetyltransferase
ACT75_01220	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
ACT75_01230	ENOG41061ZR	Transcriptional regulator
ACT75_01235	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
ACT75_01240	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
ACT75_01245	ENOG4105E96	Colicin v production protein
ACT75_01250	ENOG4105PQ6	UPF0208 membrane protein
ACT75_01255	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ACT75_01260	ENOG4108DNC	Involved in acetate metabolism (By similarity)
ACT75_01270	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACT75_01275	ENOG4105DJ0	Poly(A) Polymerase
ACT75_01280	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
ACT75_01285	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
ACT75_01290	ENOG4105BZ1	(ABC) transporter
ACT75_01295	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ACT75_01300	ENOG41085JB	UPF0434 protein
ACT75_01310	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ACT75_01330	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_01350	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
ACT75_01355	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
ACT75_01365	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ACT75_01380	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ACT75_01390	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ACT75_01395	ENOG4105CHV	Transcription elongation factor NusA
ACT75_01400	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ACT75_01470	ENOG4105ESV	Glycosyl transferase, family 4
ACT75_01475	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ACT75_01480	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
ACT75_01485	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ACT75_01490	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
ACT75_01500	ENOG4105BZ4	penicillin-binding protein
ACT75_01505	ENOG4107SJW	iron permease, FTR1
ACT75_01520	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACT75_01530	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACT75_01545	ENOG4107YBY	Hydrolase
ACT75_01555	ENOG4105CQ7	ATP-dependent helicase
ACT75_01560	ENOG4105M08	Membrane
ACT75_01565	ENOG4108VMM	UPF0756 membrane protein
ACT75_01570	ENOG4105M2J	Glutaredoxin
ACT75_01580	ENOG4105CQB	FAD linked oxidase domain protein
ACT75_01585	ENOG4105KA0	thioesterase Superfamily protein
ACT75_01595	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ACT75_01600	ENOG4105CE4	GlcNAc 6-P deacetylase
ACT75_01605	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
ACT75_01610	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACT75_01615	ENOG4105QEK	Transcriptional regulator
ACT75_01625	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
ACT75_01630	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
ACT75_01635	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ACT75_01640	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
ACT75_01645	ENOG4105CI1	PTS System
ACT75_01655	ENOG4105CS6	Rhs element vgr protein
ACT75_01670	ENOG4105NVB	glycoside hydrolase, family 19
ACT75_01735	ENOG4105E2R	ROK family
ACT75_01745	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ACT75_01750	ENOG4105D1A	Methyltransferase
ACT75_01760	ENOG4105KWI	UPF0339 protein
ACT75_01765	ENOG4105EIP	mannose-6-phosphate isomerase
ACT75_01770	ENOG4105DDY	UPF0142 protein ycaO
ACT75_01775	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
ACT75_01780	ENOG4105C0H	protease
ACT75_01800	ENOG4105D7X	high-affinity nickel-transporter
ACT75_01805	ENOG41065CD	Exported protein
ACT75_01810	ENOG4105C5H	ABC transporter
ACT75_01820	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT75_01825	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT75_01830	ENOG4108K3A	Glutathione S-transferase
ACT75_01840	ENOG4105ERU	peptidase
ACT75_01850	ENOG4105CEP	NADH dehydrogenase
ACT75_01860	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
ACT75_01865	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
ACT75_01870	ENOG41082RQ	UPF0102 protein
ACT75_01875	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ACT75_01880	ENOG4105W4M	Transport-associated protein
ACT75_01885	ENOG41077A9	carbonic anhydrase
ACT75_01890	ENOG4105E0X	reductase
ACT75_01895	ENOG4107QIV	Cytochrome c biogenesis protein
ACT75_01900	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACT75_01915	ENOG4105DQ6	Transposase
ACT75_01925	ENOG4105CEE	C4-dicarboxylate transporter
ACT75_01950	ENOG4105VT2	5-hydroxyisourate hydrolase
ACT75_01955	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ACT75_01960	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
ACT75_01965	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
ACT75_01970	ENOG4105C7N	Xanthine uracil vitamin C permease
ACT75_01975	ENOG4105KAF	membrAne
ACT75_01980	ENOG4105CMR	udp-glucose 4-epimerase
ACT75_01985	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
ACT75_01990	ENOG4105EYM	Major Facilitator superfamily
ACT75_01995	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACT75_02000	ENOG4105IYK	transposase
ACT75_02005	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ACT75_02010	ENOG4105I7R	Adenylate cyclase
ACT75_02015	ENOG4107IX6	phosphate transport regulator
ACT75_02020	ENOG4105CJ3	phosphate transporter
ACT75_02030	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACT75_02035	ENOG4108AD6	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
ACT75_02040	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ACT75_02045	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ACT75_02055	ENOG4105DAA	L-lactate
ACT75_02060	ENOG41090HJ	UPF0265 protein
ACT75_02065	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
ACT75_02070	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACT75_02090	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ACT75_02100	ENOG4107RZZ	dna polymerase iii epsilon subunit
ACT75_02120	ENOG4105K4U	addiction module toxin, RelE StbE family
ACT75_02135	ENOG4105CFP	Peptidase U32
ACT75_02175	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ACT75_02180	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACT75_02190	ENOG4105VIE	preprotein translocase, subunit YajC
ACT75_02195	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACT75_02200	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACT75_02205	ENOG4107ENK	receptor
ACT75_02210	ENOG4108EKI	Dehydrogenase
ACT75_02215	ENOG4105CNN	ABC, transporter
ACT75_02220	ENOG4105C2J	ABC transporter
ACT75_02225	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
ACT75_02235	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ACT75_02240	ENOG4105C26	Dehydrogenase
ACT75_02255	ENOG4105M6W	Crispr-associated protein, Csy3 family
ACT75_02275	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
ACT75_02280	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ACT75_02285	ENOG4107QNR	UPF0135 protein
ACT75_02290	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ACT75_02300	ENOG4108RMU	ferritin dps family protein
ACT75_02310	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ACT75_02320	ENOG4105CAF	HipA N-terminal domain protein
ACT75_02340	ENOG4105MYG	DNA polymerase iii, chi subunit
ACT75_02345	ENOG4105C9Q	fumarate hydratase class II
ACT75_02350	ENOG4105RHG	
ACT75_02360	ENOG4108DBC	nitroreductase
ACT75_02365	ENOG41090BQ	Glutaredoxin
ACT75_02370	ENOG4105CNT	hydrolase family 2
ACT75_02375	ENOG4105E0U	tyrosine-specific transport protein
ACT75_02410	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
ACT75_02415	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
ACT75_02420	ENOG4105DW5	Transcriptional regulator
ACT75_02465	ENOG4105CS6	Rhs element vgr protein
ACT75_02470	ENOG4108JQB	penicillin-binding protein 1C
ACT75_02475	ENOG4105HMI	Membrane
ACT75_02480	ENOG4105DN3	alpha-2-macroglobulin domain protein
ACT75_02485	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
ACT75_02490	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ACT75_02495	ENOG4108VEN	abc transporter atp-binding protein
ACT75_02505	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
ACT75_02520	ENOG4106J39	exported protein
ACT75_02525	ENOG4105CFG	Acts as a chaperone (By similarity)
ACT75_02530	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACT75_02535	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
ACT75_02550	ENOG4105C28	cystathionine
ACT75_02555	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ACT75_02575	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
ACT75_02580	ENOG4105E9S	glutaredoxin 2
ACT75_02585	ENOG4105C03	ribonuclease
ACT75_02590	ENOG4105CK7	Sodium proline symporter
ACT75_02600	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ACT75_02615	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ACT75_02620	ENOG4105F27	Major Facilitator
ACT75_02640	ENOG4105C4Y	ABC transporter
ACT75_02645	ENOG4105C4Y	ABC transporter
ACT75_02650	ENOG4107RCV	ABC transporter, permease
ACT75_02655	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_02665	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ACT75_02670	ENOG4105EN6	Membrane
ACT75_02680	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACT75_02685	ENOG4105DFU	Cell wall formation (By similarity)
ACT75_02695	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ACT75_02700	ENOG4105CUZ	uba thif-type nad fad binding protein
ACT75_02705	ENOG4105NXV	High-affinity zinc uptake system protein
ACT75_02710	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
ACT75_02735	ENOG4105VDB	UPF0125 protein
ACT75_02740	ENOG4105EZE	Cupin 4 family protein
ACT75_02745	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACT75_02750	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
ACT75_02755	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
ACT75_02760	ENOG4108IUZ	ABC transporter
ACT75_02765	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
ACT75_02770	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
ACT75_02775	ENOG4105DHJ	ABC, transporter
ACT75_02780	ENOG4105CY3	ABC transporter, permease
ACT75_02785	ENOG4107PE3	Mammalian cell entry related domain protein
ACT75_02790	ENOG4105E3I	toluene tolerance
ACT75_02800	ENOG4105VFK	BolA family
ACT75_02805	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ACT75_02810	ENOG4105KZW	UPF0381 protein
ACT75_02820	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ACT75_02830	ENOG4105EE5	Membrane protein terC
ACT75_02835	ENOG4105C5F	glutamine synthetase
ACT75_02840	ENOG4105CI3	gtp-binding protein typa
ACT75_02845	ENOG4108BMY	protease
ACT75_02850	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACT75_02855	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACT75_02860	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
ACT75_02870	ENOG4108IJ8	ABC transporter
ACT75_02875	ENOG4105DFA	alanine racemase domain protein
ACT75_02885	ENOG4105CFH	Aspartokinase
ACT75_02900	ENOG4105D98	threonine synthase
ACT75_02910	ENOG4107QJR	hflk protein
ACT75_02915	ENOG4105EPW	hflc protein
ACT75_02920	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ACT75_02925	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACT75_02930	ENOG4105II7	pyrroline-5-carboxylate reductase
ACT75_02935	ENOG4105DH7	May be involved in recombination (By similarity)
ACT75_02945	ENOG4108UBT	opacity-associated protein
ACT75_02950	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
ACT75_02960	ENOG4105C0F	tryptophanase EC 4.1.99.1
ACT75_02965	ENOG4105E0U	tyrosine-specific transport protein
ACT75_02970	ENOG4105WWK	YheO domain protein
ACT75_02980	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
ACT75_02985	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
ACT75_02990	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
ACT75_03000	ENOG4105F1A	Pyruvate formate-lyase
ACT75_03005	ENOG4105C6N	Formate acetyltransferase
ACT75_03010	ENOG4105TMB	Formate nitrite transporter
ACT75_03015	ENOG4105K59	histidine triad (HIT) protein
ACT75_03025	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
ACT75_03035	ENOG4105CTQ	phosphohexokinase
ACT75_03055	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ACT75_03060	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
ACT75_03065	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ACT75_03070	ENOG4105C3F	Signal peptidase i
ACT75_03085	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ACT75_03090	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACT75_03095	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ACT75_03100	ENOG4105VG0	50S ribosomal protein l34
ACT75_03105	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ACT75_03110	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ACT75_03115	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ACT75_03120	ENOG4105DVA	methyltransferase
ACT75_03125	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACT75_03130	ENOG4105CBX	hi0933 family
ACT75_03135	ENOG4108DMF	Cytochrome C biogenesis protein
ACT75_03140	ENOG4107QX9	Thiol disulfide interChange protein
ACT75_03145	ENOG4105DA4	cytochrome c-type biogenesis protein
ACT75_03150	ENOG4105DVI	reductase, NrfD
ACT75_03155	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ACT75_03160	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
ACT75_03180	ENOG4108M1T	Cytochrome c-type biogenesis protein
ACT75_03185	ENOG4108M1T	Cytochrome c-type biogenesis protein
ACT75_03190	ENOG4107QX9	Thiol disulfide interChange protein
ACT75_03195	ENOG4105DA4	cytochrome c-type biogenesis protein
ACT75_03200	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
ACT75_03205	ENOG4105X3C	heme exporter protein
ACT75_03210	ENOG41060IM	Heme exporter protein
ACT75_03215	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
ACT75_03220	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
ACT75_03225	ENOG4105C2C	drug resistance transporter, Bcr CflA
ACT75_03230	ENOG4105I08	Pseudouridine synthase
ACT75_03270	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ACT75_03275	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
ACT75_03280	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
ACT75_03285	ENOG4105E4F	Isochorismate synthase
ACT75_03290	ENOG4105CHM	Aminotransferase
ACT75_03295	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
ACT75_03300	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ACT75_03305	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
ACT75_03310	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
ACT75_03315	ENOG4107ZVW	dihydroneopterin aldolase
ACT75_03320	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ACT75_03325	ENOG4108WZM	domain protein
ACT75_03330	ENOG4105CGZ	zinc metallopeptidase
ACT75_03340	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACT75_03345	ENOG4105C6K	Malic enzyme
ACT75_03390	ENOG4105GPY	SprT protein
ACT75_03395	ENOG4105C44	Serine transporter
ACT75_03400	ENOG4105EJQ	L-serine dehydratase
ACT75_03405	ENOG4105HDK	L-asparaginase
ACT75_03415	ENOG41090FY	type IV pilus biogenesis stability protein PilW
ACT75_03420	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
ACT75_03425	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ACT75_03430	ENOG4105CUT	histidyl-tRNA synthetase
ACT75_03435	ENOG4105N21	Membrane
ACT75_03445	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
ACT75_03450	ENOG4105C2W	permease
ACT75_03455	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ACT75_03460	ENOG4105EIN	peptidylprolyl cis-trans isomerase
ACT75_03465	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ACT75_03475	ENOG4105CHH	sulfate transporter
ACT75_03495	ENOG4107YCY	Transcriptional regulator
ACT75_03510	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
ACT75_03515	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ACT75_03520	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
ACT75_03525	ENOG4105DMW	Dehydrogenase reductase
ACT75_03535	ENOG4108UHU	Aldolase
ACT75_03540	ENOG4105S10	periplasmic binding protein
ACT75_03545	ENOG4108JQ1	Dehydrogenase
ACT75_03550	ENOG4105E66	phosphoriboisomerase A
ACT75_03555	ENOG4105CSA	Coproporphyrinogen iii oxidase
ACT75_03560	ENOG4105K8R	UPF0145 protein
ACT75_03565	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ACT75_03570	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
ACT75_03580	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ACT75_03600	ENOG4105DTN	riboflavin biosynthesis protein ribF
ACT75_03605	ENOG4105CJR	Integral membrane protein (MviN
ACT75_03615	ENOG41062Z9	Membrane
ACT75_03620	ENOG4105EAC	phosphoserine phosphatase
ACT75_03625	ENOG4108VPT	UPF0234 protein
ACT75_03630	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ACT75_03635	ENOG4105C3G	gtp-binding protein
ACT75_03640	ENOG4108RG0	uracil-dna glycosylase
ACT75_03645	ENOG4105C6T	cysteine synthase
ACT75_03650	ENOG4105EXN	Sulfate transport protein CysZ
ACT75_03655	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
ACT75_03665	ENOG4107104	thymidine kinase
ACT75_03675	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACT75_03680	ENOG4105VCC	30S ribosomal protein S21
ACT75_03685	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ACT75_03690	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACT75_03700	ENOG4105DFP	Integrase
ACT75_03715	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ACT75_03720	ENOG41083MP	50s ribosomal protein l29
ACT75_03725	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ACT75_03730	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ACT75_03735	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ACT75_03740	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ACT75_03745	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACT75_03755	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ACT75_03760	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ACT75_03770	ENOG4105CMU	LysR family (Transcriptional regulator
ACT75_03775	ENOG4107QP7	CoA-transferase subunit A
ACT75_03780	ENOG4107QNJ	CoA-transferase subunit B
ACT75_03785	ENOG4105CRW	Short chain fatty acid transporter
ACT75_03790	ENOG4105CHU	acetyl-coa acetyltransferase
ACT75_03795	ENOG4105EW9	transcriptional regulator AsnC family
ACT75_03800	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
ACT75_03805	ENOG4105C5B	carbamate kinase
ACT75_03810	ENOG4105DBV	ornithine carbamoyltransferase
ACT75_03820	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACT75_03830	ENOG4108VVK	transcriptional Regulator, AsnC
ACT75_03835	ENOG4108I5U	Uridine phosphorylase
ACT75_03845	ENOG4105K89	arsenate reductase
ACT75_03860	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ACT75_03865	ENOG4105KJF	protein tyrosine phosphatase
ACT75_03875	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ACT75_03885	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
ACT75_03895	ENOG4105C1A	potassium transporter peripheral membrane
ACT75_03900	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ACT75_03940	ENOG4108RR8	protoporphyrinogen oxidase
ACT75_03945	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
ACT75_03955	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
ACT75_03960	ENOG4105W0Z	cytoplasmic protein
ACT75_03965	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
ACT75_03970	ENOG4108VVQ	metallophosphoesterase
ACT75_03975	ENOG4105E0U	tyrosine-specific transport protein
ACT75_03980	ENOG4108ZT0	50S ribosomal protein l17
ACT75_03985	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACT75_03990	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACT75_04005	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ACT75_04015	ENOG4105VPB	50S ribosomal protein L30
ACT75_04020	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ACT75_04025	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ACT75_04030	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ACT75_04035	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ACT75_04045	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACT75_04050	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ACT75_04055	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ACT75_04065	ENOG4105D52	delta-aminolevulinic acid dehydratase
ACT75_04070	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ACT75_04075	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
ACT75_04080	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACT75_04105	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
ACT75_04110	ENOG4105VEJ	Heat shock protein
ACT75_04115	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
ACT75_04120	ENOG4107RK2	ADP-ribose diphosphatase NudE
ACT75_04125	ENOG4105E7U	AraC family transcriptional regulator
ACT75_04130	ENOG4108KBJ	Inner membrane protein YkgB
ACT75_04135	ENOG4105EPD	Oligopeptide transporter, Opt family
ACT75_04145	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
ACT75_04150	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
ACT75_04155	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
ACT75_04170	ENOG4107QUT	magnesium and cobalt transport protein CorA
ACT75_04175	ENOG4108VIA	integral membrane protein
ACT75_04180	ENOG4105VZ9	UPF0235 protein
ACT75_04185	ENOG4108RCM	Nitroreductase
ACT75_04210	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
ACT75_04215	ENOG4105C34	Pseudouridine synthase
ACT75_04220	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACT75_04225	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
ACT75_04230	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
ACT75_04235	ENOG4105E07	UPF0149 protein
ACT75_04240	ENOG4107RAQ	aminopeptidase
ACT75_04270	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
ACT75_04275	ENOG4105DFF	Rod shape-determining protein mreb
ACT75_04280	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ACT75_04285	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ACT75_04290	ENOG4105CXY	transporter
ACT75_04295	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
ACT75_04300	ENOG4105C79	DNA protecting protein DprA
ACT75_04305	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ACT75_04320	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ACT75_04325	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
ACT75_04330	ENOG4105E55	glycerol-3-phosphate acyltransferase
ACT75_04335	ENOG4105BZ1	(ABC) transporter
ACT75_04340	ENOG4105E7U	AraC family transcriptional regulator
ACT75_04350	ENOG4105DKP	glycosyl transferase, family 9
ACT75_04365	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ACT75_04370	ENOG4106WTF	Glycosyl transferase, family 2
ACT75_04385	ENOG4105JIM	Phosphatidylserine synthase
ACT75_04390	ENOG4105EIB	trna rrna methyltransferase
ACT75_04395	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ACT75_04400	ENOG41083KI	ribonuclease, T2
ACT75_04410	ENOG4105D2N	Aldolase
ACT75_04415	ENOG4105PF3	O-Antigen polymerase
ACT75_04420	ENOG4108EUD	Lysophospholipase
ACT75_04425	ENOG4105DQF	Hydrolase
ACT75_04435	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACT75_04460	ENOG4105CS9	pantothenic acid kinase
ACT75_04465	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT75_04470	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ACT75_04475	ENOG4105XQ6	frataxin-like protein
ACT75_04480	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ACT75_04485	ENOG4105R3P	Inner membrane protein yagU
ACT75_04490	ENOG4108R3E	Dna-3-methyladenine glycosylase i
ACT75_04495	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ACT75_04505	ENOG4105CIN	aminoacyl-histidine dipeptidase
ACT75_04510	ENOG4108IXY	short-chain dehydrogenase reductase
ACT75_04515	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
ACT75_04520	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
ACT75_04525	ENOG4105VQK	sigma E regulatory protein, MucB RseB
ACT75_04530	ENOG41069PW	sigma-e factor negative regulatory protein
ACT75_04535	ENOG4105EMN	RNA polymerase sigma factor
ACT75_04540	ENOG4105Y75	tpr repeat protein
ACT75_04550	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ACT75_04555	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ACT75_04560	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ACT75_04615	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACT75_04620	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACT75_04645	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ACT75_04650	ENOG4108HPI	phosphatidate Cytidylyltransferase
ACT75_04660	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
ACT75_04665	ENOG4107QWE	)-transporter
ACT75_04675	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACT75_04680	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACT75_04685	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ACT75_04690	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACT75_04700	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACT75_04705	ENOG4105DZP	Membrane-associated zinc metalloprotease
ACT75_04710	ENOG4105KNE	Phosphatidate cytidylyltransferase
ACT75_04715	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ACT75_04725	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ACT75_04735	ENOG4105D0C	transport protein
ACT75_04740	ENOG4105CQ0	ABC transporter
ACT75_04745	ENOG41063SR	receptor
ACT75_04750	ENOG4105E98	transcriptional regulator DeoR family
ACT75_04755	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
ACT75_04765	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ACT75_04770	ENOG4108TEB	UPF0114 protein
ACT75_04775	ENOG4105CGY	Dna recombination protein
ACT75_04780	ENOG4108WI1	Dna topoisomerase
ACT75_04785	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACT75_04790	ENOG4105E2X	shikimate dehydrogenase
ACT75_04795	ENOG4105DTR	rard protein
ACT75_04800	ENOG4105EMY	transcriptional regulator
ACT75_04805	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ACT75_04810	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ACT75_04815	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ACT75_04825	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACT75_04830	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
ACT75_04835	ENOG4105C2J	ABC transporter
ACT75_04840	ENOG4105CNN	ABC, transporter
ACT75_04845	ENOG4105CMG	Carbohydrate kinase
ACT75_04850	ENOG4105BZM	domain protein
ACT75_04870	ENOG4107QPK	)-transporter
ACT75_04875	ENOG4108TGR	phosphatase
ACT75_04880	ENOG4105BZM	domain protein
ACT75_04885	ENOG4108RRZ	Transcription elongation factor GreB
ACT75_04895	ENOG4108WQI	RNA Polymerase
ACT75_04905	ENOG4105EX9	Membrane
ACT75_04910	ENOG410601J	HemY protein
ACT75_04915	ENOG4105ECF	c-methyltransferase
ACT75_04925	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ACT75_04930	ENOG4107T0K	Adenylate cyclase
ACT75_04935	ENOG4105WH1	Two component transcriptional regulator luxr family
ACT75_04940	ENOG4105CFU	surface antigen
ACT75_04945	ENOG4105MA0	exported protein
ACT75_04950	ENOG4105C9X	ppx gppa phosphatase
ACT75_04970	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ACT75_04975	ENOG4105R2J	Conserved Protein
ACT75_04980	ENOG4105K70	DNA-binding protein
ACT75_04985	ENOG410804X	Transcriptional regulator
ACT75_04990	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ACT75_04995	ENOG4105ENX	hydrolase
ACT75_05000	ENOG4105EQ2	LysR family Transcriptional regulator
ACT75_05010	ENOG4105EBR	Carboxylesterase
ACT75_05015	ENOG4107SET	aldo keto reductase
ACT75_05025	ENOG4105EQ2	LysR family Transcriptional regulator
ACT75_05035	ENOG4105D7A	ATP-binding protein
ACT75_05045	ENOG4105K5B	UPF0225 protein
ACT75_05050	ENOG4107S2Z	UPF0761 membrane protein
ACT75_05055	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
ACT75_05060	ENOG4105D6U	Sodium Glutamate Symporter
ACT75_05065	ENOG4105E0F	Histidine kinase
ACT75_05070	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
ACT75_05075	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
ACT75_05085	ENOG4105YDX	UPF0352 protein
ACT75_05090	ENOG4105E68	Sulfatase
ACT75_05100	ENOG4105DXN	mazG family
ACT75_05105	ENOG4108M6U	Universal stress protein A
ACT75_05110	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACT75_05115	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
ACT75_05125	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ACT75_05130	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
ACT75_05135	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ACT75_05140	ENOG4108UJU	UPF0301 protein
ACT75_05145	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ACT75_05150	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ACT75_05155	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACT75_05165	ENOG4105CJ2	(LipO)protein
ACT75_05170	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
ACT75_05175	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACT75_05180	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACT75_05185	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACT75_05200	ENOG4105M85	Bola protein
ACT75_05205	ENOG4105IEY	(LipO)protein
ACT75_05220	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
ACT75_05225	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
ACT75_05230	ENOG4105CEN	a g-specific adenine glycosylase
ACT75_05235	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ACT75_05240	ENOG41090ED	Protein with unknown function (DUF469)
ACT75_05245	ENOG4107QKW	extracellular solute-binding protein family 1
ACT75_05250	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
ACT75_05255	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_05260	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
ACT75_05265	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ACT75_05270	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ACT75_05275	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
ACT75_05280	ENOG4105DSJ	YicC domain protein
ACT75_05285	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
ACT75_05300	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ACT75_05305	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
ACT75_05310	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACT75_05315	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACT75_05320	ENOG41080IJ	Diacylglycerol kinase
ACT75_05330	ENOG4108BSC	Methyltransferase
ACT75_05335	ENOG4105BZS	acriflavin resistance protein
ACT75_05340	ENOG410624X	efflux transporter, rnd family, mfp subunit
ACT75_05345	ENOG4105Y7M	Transcriptional regulator, TetR family
ACT75_05350	ENOG41063M6	Cell Division Protein
ACT75_05355	ENOG4105C25	Primosomal protein n'
ACT75_05360	ENOG4108SEH	involved in lipopolysaccharide biosynthesis
ACT75_05370	ENOG4105W1T	Glycosyl Transferase
ACT75_05380	ENOG4105W1T	Glycosyl Transferase
ACT75_05400	ENOG4105W0E	50S ribosomal protein L33
ACT75_05415	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
ACT75_05425	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
ACT75_05430	ENOG4105YP7	UPF0270 protein
ACT75_05435	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
ACT75_05440	ENOG4105DC8	reductase
ACT75_05445	ENOG4105D6S	protein involved in catabolism of external DNA
ACT75_05450	ENOG4108JQC	penicillin-binding protein 1A
ACT75_05475	ENOG4105E4G	Type IV pilus
ACT75_05480	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ACT75_05485	ENOG4105D49	3-dehydroquinate synthase
ACT75_05490	ENOG4105DFE	Dna adenine methylase
ACT75_05520	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACT75_05530	ENOG4108UUM	single-stranded DNA-binding protein
ACT75_05535	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ACT75_05550	ENOG4105W1Y	Transcriptional regulator
ACT75_05565	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACT75_05570	ENOG4105M6F	mutator MutT protein
ACT75_05575	ENOG4105DJF	DNA polymerase III, delta' subunit
ACT75_05590	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ACT75_05595	ENOG41060A7	DNA polymerase beta domain protein region
ACT75_05600	ENOG41062MS	nucleotidyltransferase substrate binding protein
ACT75_05605	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
ACT75_05610	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ACT75_05615	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ACT75_05620	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
ACT75_05630	ENOG41075W9	High frequency lysogenization protein HflD homolog
ACT75_05635	ENOG4107QTF	adenylosuccinate lyase
ACT75_05640	ENOG4105EMU	Dehydrogenase
ACT75_05645	ENOG4105VUF	Transcriptional regulator
ACT75_05650	ENOG4107QPD	alcohol dehydrogenase
ACT75_05655	ENOG4105C4W	S-formylglutathione hydrolase
ACT75_05660	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACT75_05665	ENOG4106KVJ	cytochrome C assembly protein
ACT75_05670	ENOG4108JU6	CBS domain protein
ACT75_05675	ENOG4105M8K	biopolymer transport protein
ACT75_05680	ENOG4105M15	transport protein ExbD
ACT75_05685	ENOG41067XB	TonB family
ACT75_05690	ENOG4105ERG	peptidase m48, ste24p
ACT75_05695	ENOG4105F0N	pyrophosphate phospho-hydrolase
ACT75_05700	ENOG4105CIC	tryptophan-specific transport protein
ACT75_05720	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ACT75_05725	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
ACT75_05730	ENOG410903C	(LipO)protein
ACT75_05735	ENOG4105XWI	UPF0304 protein
ACT75_05740	ENOG4105CS6	Rhs element vgr protein
ACT75_05770	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
ACT75_05775	ENOG4107XM3	UPF0442 protein
ACT75_05780	ENOG4105DWK	Membrane
ACT75_05785	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACT75_05790	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACT75_05795	ENOG4108V1T	peptidylprolyl cis-trans isomerase
ACT75_05800	ENOG4105DJ4	phosphatidylserine decarboxylase
ACT75_05805	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
ACT75_05810	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ACT75_05815	ENOG4105HSA	Protein of unknown function (DUF452)
ACT75_05820	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
ACT75_05825	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ACT75_05830	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
ACT75_05835	ENOG4105VGS	50s ribosomal protein l32
ACT75_05840	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ACT75_05850	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ACT75_05855	ENOG4105CHR	reductase
ACT75_05865	ENOG4107RGD	Major Facilitator superfamily
ACT75_05870	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ACT75_05875	ENOG4105C1J	atp-dependent rna helicase
ACT75_05880	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
ACT75_05890	ENOG4105CJN	penicillin-binding protein
ACT75_05895	ENOG4105CNI	cell division protein FtsW
ACT75_05900	ENOG4105K6T	rare lipoprotein A
ACT75_05905	ENOG4105DZ1	carboxypeptidase
ACT75_05920	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ACT75_05935	ENOG4105CJP	fad dependent oxidoreductase
ACT75_05940	ENOG4105EAB	amino acid AbC transporter
ACT75_05945	ENOG4105E5Q	amino acid AbC transporter
ACT75_05950	ENOG4105CDA	abc transporter atp-binding protein
ACT75_05960	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
ACT75_05965	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
ACT75_05970	ENOG4105WWK	YheO domain protein
ACT75_05975	ENOG4108V1T	peptidylprolyl cis-trans isomerase
ACT75_05985	ENOG4105EHV	domain protein
ACT75_05990	ENOG4105C5Q	Transcriptional regulator
ACT75_05995	ENOG4105EJ2	Transcriptional regulator
ACT75_06000	ENOG4105BZ1	(ABC) transporter
ACT75_06005	ENOG4108JJ9	ABC, transporter
ACT75_06010	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
ACT75_06015	ENOG4107YZP	Rhodanese domain protein
ACT75_06020	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
ACT75_06025	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ACT75_06030	ENOG4105D7W	serine acetyltransferase
ACT75_06040	ENOG4105CBT	Fructose-1,6-bisphosphatase
ACT75_06045	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
ACT75_06050	ENOG4105QTB	Flavodoxin
ACT75_06060	ENOG4105ECR	NmrA family
ACT75_06065	ENOG4105KVH	Transcriptional regulator
ACT75_06070	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ACT75_06090	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACT75_06095	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACT75_06105	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ACT75_06115	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ACT75_06120	ENOG4107RUE	extracellular solute-binding protein family 1
ACT75_06125	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACT75_06130	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
ACT75_06135	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ACT75_06145	ENOG4107FB0	transcriptional regulator DeoR family
ACT75_06255	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ACT75_06260	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACT75_06265	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ACT75_06275	ENOG4108IJ0	Aspartate ammonia-lyase
ACT75_06280	ENOG4105M5K	heptosyltransferase
ACT75_06285	ENOG4105F3R	pts system mannose fructose sorbose family iid
ACT75_06290	ENOG4105ETZ	PTS System
ACT75_06295	ENOG4108EQA	pts system
ACT75_06300	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ACT75_06305	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
ACT75_06310	ENOG4105MFV	ABC-2 type transporter
ACT75_06325	ENOG4107TXM	Nad-dependent epimerase dehydratase
ACT75_06330	ENOG4105EXC	Acyl-transferase
ACT75_06335	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
ACT75_06345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ACT75_06350	ENOG4105D3Q	Sugar transferase
ACT75_06355	ENOG4105T16	Transcriptional regulator (AraC family)
ACT75_06360	ENOG4105DFD	Na H antiporter
ACT75_06365	ENOG4105C87	Aminotransferase class I and II
ACT75_06370	ENOG4108HWW	ABC transporter
ACT75_06375	ENOG4105C2J	ABC transporter
ACT75_06380	ENOG4105DFW	ABC transporter
ACT75_06385	ENOG4105C93	Xylose Isomerase
ACT75_06410	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACT75_06420	ENOG4105D4A	Cell wall formation (By similarity)
ACT75_06425	ENOG4105BZU	Histidine kinase
ACT75_06440	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ACT75_06445	ENOG4105GXZ	Ferredoxin-type protein NapH
ACT75_06450	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ACT75_06455	ENOG4105CUW	cytochrome C-TYPE protein
ACT75_06460	ENOG4106032	Glutathionylspermidine synthase
ACT75_06465	ENOG4105XA0	heptosyltransferase ii
ACT75_06475	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
ACT75_06480	ENOG4106W3N	
ACT75_06485	ENOG4105CGH	5'-nucleotidase
ACT75_06510	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACT75_06515	ENOG4105C2D	reductase
ACT75_06525	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACT75_06580	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ACT75_06605	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
ACT75_06610	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACT75_06615	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ACT75_06620	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
ACT75_06625	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ACT75_06635	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACT75_06640	ENOG4105KQC	Competence protein
ACT75_06645	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACT75_06650	ENOG4108X4Q	Hydrolase
ACT75_06655	ENOG4105MJ2	Competence protein
ACT75_06660	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
ACT75_06665	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ACT75_06670	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
ACT75_06675	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ACT75_06690	ENOG4105DFS	Conserved Protein
ACT75_06700	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
ACT75_06715	ENOG4108NEM	leader-binding protein dmsD
ACT75_06720	ENOG4107KGK	dmso reductase anchor subunit
ACT75_06725	ENOG4105QAX	Iron-sulfur
ACT75_06730	ENOG4107QY8	reductase
ACT75_06740	ENOG4105C2M	dna polymerase I
ACT75_06755	ENOG4105C4R	Atp-dependent dna helicase
ACT75_06780	ENOG4107VXZ	Hydrolase
ACT75_06785	ENOG4108UW5	maltose o-acetyltransferase
ACT75_06790	ENOG4105W39	Membrane
ACT75_06875	ENOG4105XB7	anti-repressor protein
ACT75_06920	ENOG4105DFP	Integrase
ACT75_06925	ENOG410689M	(LipO)protein
ACT75_06935	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ACT75_06940	ENOG4105C5H	ABC transporter
ACT75_06945	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ACT75_06950	ENOG4105Y3E	Modulates RecA activity (By similarity)
ACT75_06955	ENOG4105KME	endoribonuclease L-psp
ACT75_06960	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ACT75_06965	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ACT75_07020	ENOG4105C1J	atp-dependent rna helicase
ACT75_07025	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
ACT75_07035	ENOG4105D3G	Pseudouridine synthase
ACT75_07045	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
ACT75_07050	ENOG4105XCT	Protein of unknown function (DUF2489)
ACT75_07055	ENOG4105D4P	Coproporphyrinogen iii oxidase
ACT75_07060	ENOG4108HYK	gCN5-related N-acetyltransferase
ACT75_07070	ENOG4108IPT	Naphthoate synthase
ACT75_07085	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
ACT75_07090	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ACT75_07095	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ACT75_07100	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACT75_07115	ENOG4105RG0	Membrane
ACT75_07120	ENOG4108IA2	Sodium pantothenate symporter
ACT75_07125	ENOG4105MZU	cell filamentation protein
ACT75_07135	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACT75_07140	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
ACT75_07150	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
ACT75_07155	ENOG4105BZG	amino acid carrier protein
ACT75_07165	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
ACT75_07200	ENOG4105D9M	gamma-glutamylcysteine synthetase
ACT75_07205	ENOG4108I6E	Sulfatase
ACT75_07210	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ACT75_07215	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ACT75_07230	ENOG4105NX3	Membrane
ACT75_07235	ENOG4105C59	p-type ATPase
ACT75_07260	ENOG4105M7P	phage repressor
ACT75_07265	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACT75_07270	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACT75_07275	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ACT75_07280	ENOG4108VZM	50s ribosomal protein L10
ACT75_07295	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ACT75_07300	ENOG4105PM1	preprotein translocase subunit SecE
ACT75_07345	ENOG4105D7Q	type ii secretion system
ACT75_07350	ENOG4107QHF	type ii secretion system protein e
ACT75_07360	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
ACT75_07365	ENOG4108R66	Conserved Protein
ACT75_07375	ENOG4105RT1	May be involved in cell division (By similarity)
ACT75_07380	ENOG4105C1J	atp-dependent rna helicase
ACT75_07390	ENOG4107VHA	regulatoR
ACT75_07395	ENOG4107QQ0	gntp family
ACT75_07400	ENOG4105BZW	Glycerate kinase
ACT75_07405	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
ACT75_07410	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
ACT75_07415	ENOG4105N42	UPF0307 protein
ACT75_07420	ENOG4105C8P	)-transporter
ACT75_07430	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
ACT75_07435	ENOG4108R96	Methyltransferase, YaeB family
ACT75_07465	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
ACT75_07470	ENOG4105CAK	Cell division ATP-binding protein ftsE
ACT75_07475	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACT75_07480	ENOG4106H78	methyltransferase
ACT75_07485	ENOG4108EQA	pts system
ACT75_07490	ENOG4105ETZ	PTS System
ACT75_07495	ENOG4105F3R	pts system mannose fructose sorbose family iid
ACT75_07500	ENOG410667J	hydrolase
ACT75_07505	ENOG4105D9N	nucleoside
ACT75_07520	ENOG4107BJW	polysaccharide deacetylase
ACT75_07525	ENOG4105CND	Glycosyl transferase, family 2
ACT75_07535	ENOG4105CXY	transporter
ACT75_07560	ENOG4105DQ6	Transposase
ACT75_07580	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ACT75_07585	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ACT75_07590	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ACT75_07595	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACT75_07600	ENOG4105CB5	ATP-dependent DNA helicase recG
ACT75_07605	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
ACT75_07610	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ACT75_07645	ENOG4105KT7	mgtC SapB transporter
ACT75_07650	ENOG4108R99	pseudouridine synthase
ACT75_07655	ENOG4105C8J	)-transporter
ACT75_07660	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ACT75_07665	ENOG4105C31	Tryptophanyl-tRNA synthetase
ACT75_07670	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACT75_07675	ENOG4105DJV	ribulose-phosphate 3-epimerase
ACT75_07680	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
ACT75_07685	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
ACT75_07695	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ACT75_07700	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ACT75_07705	ENOG4108UM1	dedA family
ACT75_07715	ENOG4108K5P	(LipO)protein
ACT75_07730	ENOG4105E2D	ec 3.2.1.52
ACT75_07735	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ACT75_07740	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ACT75_07750	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ACT75_07755	ENOG4108JU5	Magnesium and cobalt efflux protein
ACT75_07760	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
ACT75_07770	ENOG4105CI0	Citrate lyase
ACT75_07775	ENOG4105CHY	citrate lyase, alpha
ACT75_07780	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
ACT75_07785	ENOG4107QPK	)-transporter
ACT75_07800	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
ACT75_07810	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
ACT75_07815	ENOG41060NJ	transcriptional regulator
ACT75_07820	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
ACT75_07830	ENOG4108HWV	)-transporter
ACT75_07835	ENOG4105BZU	Histidine kinase
ACT75_07840	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACT75_07845	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ACT75_07855	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACT75_07865	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ACT75_07880	ENOG4107835	probably involved in intracellular septation (By similarity)
ACT75_07885	ENOG4105NAU	thioesterase Superfamily protein
ACT75_07890	ENOG4105K9H	YciI-like protein
ACT75_07895	ENOG4107SC1	transglycosylase
ACT75_07900	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
ACT75_07905	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
ACT75_07925	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ACT75_07930	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ACT75_07935	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ACT75_07940	ENOG4105DIN	metallophosphoesterase
ACT75_07945	ENOG4108HUF	Transporter
ACT75_07950	ENOG4105DQ5	transport system permease protein
ACT75_07955	ENOG4108IHU	transport system permease protein
ACT75_07960	ENOG4105E0A	ABC, transporter
ACT75_07965	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
ACT75_07970	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ACT75_07975	ENOG4105E33	succinate dehydrogenase
ACT75_07980	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
ACT75_07985	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
ACT75_07990	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
ACT75_08005	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ACT75_08020	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
ACT75_08025	ENOG41087AY	ADP-Ribose pyrophosphatase
ACT75_08040	ENOG4105KUZ	arsenate reductase
ACT75_08045	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ACT75_08050	ENOG4105CQC	Prephenate dehydratase
ACT75_08060	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ACT75_08065	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ACT75_08070	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
ACT75_08075	ENOG4105CPF	Cell wall formation (By similarity)
ACT75_08080	ENOG4105DFU	Cell wall formation (By similarity)
ACT75_08085	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
ACT75_08090	ENOG4105CNI	cell division protein FtsW
ACT75_08095	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ACT75_08100	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ACT75_08105	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
ACT75_08110	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ACT75_08115	ENOG4105CJN	penicillin-binding protein
ACT75_08125	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ACT75_08130	ENOG4108V6E	Cell division protein mraZ
ACT75_08140	ENOG4105DMR	ABC, transporter
ACT75_08145	ENOG4105GBT	ABC transporter
ACT75_08150	ENOG4106PMH	Extracellular solute-binding protein family 3
ACT75_08155	ENOG4105E5Z	arginine transporter ATP-binding subunit
ACT75_08165	ENOG4108JA2	transcriptioN-repair coupling factor
ACT75_08185	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ACT75_08315	ENOG4105DM4	PTS System
ACT75_08320	ENOG4105DE4	1-phosphofructokinase
ACT75_08325	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
ACT75_08335	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
ACT75_08345	ENOG4108Z33	Thiol disulfide Interchange Protein
ACT75_08350	ENOG4108WFC	UPF0438 protein yifE
ACT75_08355	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
ACT75_08360	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
ACT75_08395	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ACT75_08400	ENOG4108K4B	hydrolase
ACT75_08425	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
ACT75_08430	ENOG4105FB2	class II Aldolase
ACT75_08435	ENOG4105G63	Type III effector Hrp-dependent
ACT75_08440	ENOG4105ZXK	Dehydrogenase
ACT75_08445	ENOG4105MVE	transcriptional regulator
ACT75_08450	ENOG4108YZA	Nitrogen regulatory protein pii
ACT75_08455	ENOG4105HHA	aminodeoxychorismate lyase
ACT75_08460	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ACT75_08465	ENOG4107QRG	dna polymerase iii
ACT75_08470	ENOG4105F8V	Hydrolase, tatD family
ACT75_08475	ENOG4105RX8	Protein of unknown function (DUF1523)
ACT75_08480	ENOG4105C37	(CBS) domain
ACT75_08505	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ACT75_08510	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
ACT75_08515	ENOG41063SB	peptidase
ACT75_08520	ENOG4105PXI	polysaccharide deacetylase
ACT75_08525	ENOG4105C0P	Mg chelatase subunit ChlI
ACT75_08530	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ACT75_08535	ENOG4108MJ5	VirK protein
ACT75_08540	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ACT75_08550	ENOG4105D01	(LipO)protein
ACT75_08560	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_08565	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
ACT75_08615	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACT75_08625	ENOG4105EYA	deoxyribonuclease
ACT75_08630	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
ACT75_08635	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
ACT75_08645	ENOG4108IQE	Amp-dependent synthetase and ligase
ACT75_08650	ENOG4105C0B	DNA polymerase III (alpha subunit)
ACT75_08670	ENOG4105CH6	catalase
ACT75_08675	ENOG4105D82	Glutamate dehydrogenase
ACT75_08680	ENOG4105CH7	arginosuccinase
ACT75_08685	ENOG4108ST3	glycosyltransferase
ACT75_08715	ENOG4108KU3	Integrase
ACT75_08820	ENOG4105XB7	anti-repressor protein
ACT75_08830	ENOG4105CDU	Replicative dna helicase
ACT75_08850	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACT75_08870	ENOG4105WXW	Antirepressor
ACT75_08890	ENOG4105NVB	glycoside hydrolase, family 19
ACT75_08905	ENOG41061CV	Terminase small subunit 
ACT75_08915	ENOG4107ZQ5	Phage-associated protein, HI1409 family
ACT75_08920	ENOG4108C66	Inherit from COG: DNA primase
ACT75_08930	ENOG41090AG	Bacteriophage protein
ACT75_08955	ENOG4106GMR	
ACT75_09040	ENOG4105VEQ	Cold shock protein
ACT75_09045	ENOG4108RVA	ribokinase
ACT75_09050	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
ACT75_09055	ENOG4105CNN	ABC, transporter
ACT75_09060	ENOG4105C2J	ABC transporter
ACT75_09065	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
ACT75_09070	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ACT75_09075	ENOG4105HF0	Membrane
ACT75_09085	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ACT75_09095	ENOG4108Z6B	deaminase
ACT75_09135	ENOG4105D1F	ATP-binding protein
ACT75_09140	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACT75_09145	ENOG4105WVQ	Fe-S assembly protein IscX
ACT75_09150	ENOG4108ZIT	Ferredoxin, 2FE-2S
ACT75_09155	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
ACT75_09160	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
ACT75_09165	ENOG4108Z4V	iron-sulfur cluster assembly
ACT75_09170	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
ACT75_09180	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
ACT75_09185	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
ACT75_09190	ENOG4105ECY	inositol monophosphatase
ACT75_09250	ENOG4105C5I	Dehydrogenase
ACT75_09255	ENOG4105K63	Thioredoxin
ACT75_09260	ENOG4105EI2	Pseudouridine synthase
ACT75_09265	ENOG4105C03	ribonuclease
ACT75_09275	ENOG4105MGM	doxx family
ACT75_09285	ENOG4108URH	decarboxylase
ACT75_09290	ENOG4105NRA	50s ribosomal protein l31 type b
ACT75_09295	ENOG4105YK5	50S ribosomal protein L36
ACT75_09300	ENOG41065U4	response regulator
ACT75_09305	ENOG4108JQ7	(ABC) transporter
ACT75_09310	ENOG4105C3U	ABC transporter
ACT75_09315	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACT75_09320	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACT75_09325	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACT75_09330	ENOG4108J59	Extracellular solute-binding protein, family 5
ACT75_09340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACT75_09345	ENOG4105QYV	Membrane
ACT75_09350	ENOG4105QYV	Membrane
ACT75_09365	ENOG4105EAH	synthase
ACT75_09370	ENOG4105WPN	DNA integration recombination invertion protein
ACT75_09375	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACT75_09385	ENOG4105D3Y	Na H antiporter
ACT75_09390	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
ACT75_09395	ENOG4108UYE	Lactoylglutathione lyase
ACT75_09400	ENOG4107ENK	receptor
ACT75_09405	ENOG4105CXY	transporter
ACT75_09420	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
ACT75_09425	ENOG4105C9M	aspartyl-trna synthetase
ACT75_09430	ENOG4105DQ6	Transposase
ACT75_09440	ENOG4105K3M	)-transporter
ACT75_09445	ENOG4108TIT	dATP pyrophosphohydrolase
ACT75_09450	ENOG4105CDY	transcriptional regulatory protein
ACT75_09480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
ACT75_09485	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
ACT75_09495	ENOG4107YD3	Thioesterase
ACT75_09500	ENOG4105E02	MotA TolQ exbB proton channel
ACT75_09515	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ACT75_09520	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ACT75_09560	ENOG4105DSY	exodeoxyribonuclease V, gamma
ACT75_09565	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
ACT75_09570	ENOG4108WPU	DNA polymerase III subunit psi
ACT75_09575	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
ACT75_09580	ENOG4105C5Y	PTS System
ACT75_09590	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACT75_09605	ENOG4105DDI	hemolysin-type calcium-binding region
ACT75_09610	ENOG4108JJA	ABC, transporter
ACT75_09615	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ACT75_09620	ENOG4105CTS	PTS system mannitol-specific
ACT75_09625	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
ACT75_09630	ENOG4105E61	Mannitol repressor protein
ACT75_09635	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ACT75_09640	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
ACT75_09645	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
ACT75_09650	ENOG4105D7K	pfkb domain protein
ACT75_09700	ENOG4108IUS	Transketolase
ACT75_09705	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
ACT75_09710	ENOG4108DG9	Smr protein MutS2
ACT75_09715	ENOG4105EM2	membrane
ACT75_09720	ENOG410901E	Membrane
ACT75_09725	ENOG4108Z5K	methylglyoxal synthase
ACT75_09730	ENOG41068P6	UPF0319 protein
ACT75_09735	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
ACT75_09740	ENOG4105CC5	ABC transporter
ACT75_09745	ENOG4105CC5	ABC transporter
ACT75_09750	ENOG4105DIK	(ABC) transporter
ACT75_09760	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
ACT75_09765	ENOG4108MN8	Membrane
ACT75_09780	ENOG4105C0D	helicase
ACT75_09795	ENOG4107QMH	DNA methylase
ACT75_09810	ENOG4105FB9	CRISPR-associated protein
ACT75_09840	ENOG4105DWF	phosphomethylpyrimidine kinase
ACT75_09840	ENOG4105DWF	phosphomethylpyrimidine kinase
ACT75_09845	ENOG4105DP9	ABC transporter
ACT75_09850	ENOG4106SMU	thiamine transporter membrane protein
ACT75_09855	ENOG4107T0D	ABC, transporter
ACT75_09865	ENOG4105EW9	transcriptional regulator AsnC family
ACT75_09870	ENOG4105CNU	cell division protein FtsK
ACT75_09875	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
ACT75_09880	ENOG4105D1H	recombination factor protein RarA
ACT75_09885	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
ACT75_09895	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
ACT75_09900	ENOG4107RUE	extracellular solute-binding protein family 1
ACT75_09905	ENOG4105D38	putrescine abc transporter
ACT75_09910	ENOG4105F38	ABC transporter, permease
ACT75_09915	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_09920	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
ACT75_09925	ENOG4105DY2	Paraquat-inducible protein b
ACT75_09930	ENOG4105H2K	paraquat-inducible protein a
ACT75_09935	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
ACT75_09940	ENOG4105CN1	protease
ACT75_09945	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
ACT75_09950	ENOG4105EAQ	(twin-arginine translocation) pathway signal
ACT75_09955	ENOG4105C5X	domain protein
ACT75_09960	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
ACT75_09965	ENOG4105C7S	Dehydrogenase
ACT75_09970	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
ACT75_09975	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
ACT75_09995	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ACT75_10000	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ACT75_10010	ENOG4108MG9	hydrogenase 3 maturation protease
ACT75_10015	ENOG4105I6X	formate hydrogenlyase maturation
ACT75_10020	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
ACT75_10030	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACT75_10035	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACT75_10040	ENOG4107WQX	hydrogenase 4 membrane subunit
ACT75_10045	ENOG4105D65	subunit l
ACT75_10050	ENOG4107TDF	Formate hydrogenlyase subunit 4
ACT75_10055	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACT75_10060	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
ACT75_10065	ENOG4105C8H	hydrogenase maturation protein Hypf
ACT75_10070	ENOG4108MG3	formate dehydrogenase
ACT75_10075	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ACT75_10090	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ACT75_10095	ENOG4105DIQ	Transcriptional regulator
ACT75_10100	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
ACT75_10105	ENOG4105C6Z	Gluconate
ACT75_10110	ENOG4105C4R	Atp-dependent dna helicase
ACT75_10120	ENOG41080C8	DUF218 domain
ACT75_10125	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ACT75_10135	ENOG4108ZPC	Polysaccharide pyruvyl transferase
ACT75_10145	ENOG41068D6	Glycosyltransferase
ACT75_10155	ENOG4108RJ9	Glycosyl transferase, family 2
ACT75_10160	ENOG4108RYC	glycosyltransferase
ACT75_10165	ENOG4105CVE	Lytic murein transglycosylase
ACT75_10170	ENOG4105CGK	Exodeoxyribonuclease III
ACT75_10175	ENOG4105GXY	Family of unknown function (DUF695) 
ACT75_10180	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ACT75_10190	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ACT75_10195	ENOG4105EYK	Phosphatidylglycerophosphatase B
ACT75_10200	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
ACT75_10210	ENOG4105F3T	(LipO)protein
ACT75_10220	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
ACT75_10225	ENOG4105C29	acyl-CoA thioesterase
ACT75_10230	ENOG4108JJ8	(ABC) transporter
ACT75_10235	ENOG4108JJ9	ABC, transporter
ACT75_10240	ENOG4105C3M	thioredoxin reductase
ACT75_10245	ENOG4107QR8	Thioredoxin
ACT75_10255	ENOG4105D06	uba thif-type nad fad binding protein
ACT75_10260	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACT75_10265	ENOG4105EUJ	GTP cyclohydrolase i
ACT75_10270	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
ACT75_10275	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACT75_10280	ENOG4105HBR	Rna-binding protein
ACT75_10285	ENOG4105VUH	addiction module killer protein
ACT75_10290	ENOG4105YES	addiction module antidote protein
ACT75_10295	ENOG4108R6K	riboflavin synthase, subunit alpha
ACT75_10300	ENOG4107QI1	Mate efflux family protein
ACT75_10310	ENOG4105CQ0	ABC transporter
ACT75_10315	ENOG4108Z66	YbaK ebsC protein
ACT75_10320	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACT75_10330	ENOG4105NBI	YecM protein
ACT75_10335	ENOG4108XTF	Outer Membrane Lipoprotein
ACT75_10340	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ACT75_10345	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACT75_10350	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ACT75_10355	ENOG4107TT5	NLP P60 protein
ACT75_10370	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
ACT75_10380	ENOG4108BY2	phosphohistidine phosphatase
ACT75_10390	ENOG4105EEI	dihydropteroate synthase
ACT75_10395	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ACT75_10415	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACT75_10420	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
ACT75_10455	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
ACT75_10460	ENOG4108EU3	peptide transport system, permease
ACT75_10470	ENOG4108EVY	peptide transport periplasmic protein
ACT75_10475	ENOG4105CM6	amino acid regulated cytosolic protein
ACT75_10480	ENOG4106K28	UPF0283 membrane protein
ACT75_10485	ENOG4108JU8	Transcriptional regulator
ACT75_10490	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
ACT75_10500	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
ACT75_10505	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ACT75_10510	ENOG4105K8N	protein family UPF0079, ATPase
ACT75_10520	ENOG410838F	Glycosyl transferase family 2
ACT75_10525	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ACT75_10535	ENOG4108I6E	Sulfatase
ACT75_10570	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
ACT75_10585	ENOG4106BMH	cytolethal distending toxin
ACT75_10590	ENOG4108TMH	cytolethal distending toxin
ACT75_10665	ENOG4105KZ7	phosphocarrier protein hpr
ACT75_10670	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
ACT75_10675	ENOG4105C5Y	PTS System
ACT75_10680	ENOG4105DGW	oligopeptidase A
ACT75_10685	ENOG4105WD1	Membrane
ACT75_10725	ENOG4105CRQ	synthase (Component I)
ACT75_10730	ENOG4105DDQ	anthranilate synthase
ACT75_10735	ENOG4105C5I	Dehydrogenase
ACT75_10745	ENOG4105FGM	Fructosamine kinase
ACT75_10750	ENOG4105C22	threonyL-tRNA synthetase
ACT75_10765	ENOG4105DP0	ferredoxin-NADP reductase
ACT75_10770	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ACT75_10780	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ACT75_10790	ENOG4105D2M	Aldolase
ACT75_10795	ENOG4105DT3	PTS system, galactitol-specific IIc component
ACT75_10800	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
ACT75_10805	ENOG4105E98	transcriptional regulator DeoR family
ACT75_10810	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ACT75_10815	ENOG4105CTB	Polyprenyl synthetase
ACT75_10820	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACT75_10825	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ACT75_10830	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ACT75_10835	ENOG4108TGR	phosphatase
ACT75_10840	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ACT75_10845	ENOG4105DWU	Membrane
ACT75_10850	ENOG4108W1A	pseudouridine synthase
ACT75_10860	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ACT75_10870	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ACT75_10880	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ACT75_10900	ENOG4108ZZ3	UPF0260 protein
ACT75_10930	ENOG4105D60	lipoprotein releasing system transmembrane protein
ACT75_10940	ENOG4105D60	lipoprotein releasing system transmembrane protein
ACT75_10945	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
ACT75_10950	ENOG4105CDU	Replicative dna helicase
ACT75_10955	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ACT75_10960	ENOG4107QP8	phosphohexose isomerase
ACT75_10970	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ACT75_10980	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ACT75_10985	ENOG4108ZAI	phosphatidylglycerophosphatase a
ACT75_10990	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
ACT75_11000	ENOG4105XPH	Ferredoxin
ACT75_11010	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACT75_11025	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACT75_11035	ENOG4105C4Y	ABC transporter
ACT75_11040	ENOG4107RCV	ABC transporter, permease
ACT75_11045	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT75_11050	ENOG4107T9C	Alpha amylase catalytic region
ACT75_11055	ENOG4105EG2	ABC transporter, permease
ACT75_11060	ENOG4105D56	permease protein
ACT75_11065	ENOG4107FKK	extracellular solute-binding protein family 1
ACT75_11070	ENOG4108IJ9	(ABC) transporter
ACT75_11075	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
ACT75_11080	ENOG4107W52	maltose operon periplasmic protein
ACT75_11085	ENOG4105DSB	aldose 1-epimerase
ACT75_11090	ENOG4105DVT	helicase
ACT75_11095	ENOG41072GX	Peptidase M22 Glycoprotease
ACT75_11100	ENOG4105R8X	Outer membrane lipoprotein Slp
ACT75_11105	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT75_11110	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT75_11115	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
ACT75_11120	ENOG4105CA0	peroxidase
ACT75_11145	ENOG4107QX8	SPFH domain, Band 7 family protein
ACT75_11155	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
ACT75_11160	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
ACT75_11165	ENOG4105D1S	lipid A biosynthesis
ACT75_11170	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ACT75_11175	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ACT75_11180	ENOG4105C9B	Cysteine desulfurase
ACT75_11185	ENOG4105KK6	nuclease
ACT75_11205	ENOG4106ZKY	
ACT75_11210	ENOG4105S10	periplasmic binding protein
ACT75_11215	ENOG4105EHG	Permease protein
ACT75_11220	ENOG4105E0A	ABC, transporter
ACT75_11230	ENOG4107RNH	Outer membrane receptor FepA
ACT75_11235	ENOG4105X1Q	TOBE domain protein
ACT75_11245	ENOG4105E0A	ABC, transporter
ACT75_11250	ENOG4105EHG	Permease protein
ACT75_11280	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACT75_11290	ENOG4105M00	molybdopterin converting factor, subunit 1
ACT75_11295	ENOG4108ZAF	Molybdopterin
ACT75_11300	ENOG4107MKT	Stringent starvation protein a
ACT75_11305	ENOG4105KB2	stringent starvation protein b
ACT75_11310	ENOG4105C5S	asparaginyl-tRNA synthetase
ACT75_11315	ENOG4105DAG	ROK family
ACT75_11320	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ACT75_11325	ENOG4107RYS	Autoinducer-2 (AI-2) kinase
ACT75_11330	ENOG4105DKT	Transcriptional regulator
ACT75_11355	ENOG41061GT	Aldolase
ACT75_11365	ENOG4105CA9	Pyruvate kinase
ACT75_11375	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACT75_11385	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACT75_11390	ENOG4105EMU	Dehydrogenase
ACT75_11400	ENOG4108MVK	Receptor
ACT75_11405	ENOG4108MVK	Receptor
ACT75_11410	ENOG4105D9Q	decarboxylase (Beta subunit)
ACT75_11415	ENOG4107QSA	Oxaloacetate decarboxylase
ACT75_11420	ENOG4106AFN	Lyase and sodium transporter (By similarity)
ACT75_11440	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ACT75_11445	ENOG41082AG	Plasmid maintenance system antidote protein
ACT75_11455	ENOG4107QYG	anthranilate phosphoribosyltransferase
ACT75_11460	ENOG4108V5Q	transglutaminase-like protein
ACT75_11465	ENOG4105DDQ	anthranilate synthase
ACT75_11470	ENOG4105CRQ	synthase (Component I)
ACT75_11475	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ACT75_11480	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACT75_11485	ENOG4105D0M	Protease HtpX homolog
ACT75_11490	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ACT75_11495	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ACT75_11500	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ACT75_11505	ENOG4108QBX	(LipO)protein
ACT75_11515	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ACT75_11520	ENOG4105CMI	transporter