locus-tag	class	description
ANH9381_0014	COG3064	Membrane
ANH9381_0015	COG0848	biopolymer transport protein
ANH9381_0016	COG0811	peptide transport
ANH9381_0017	COG0824	Thioesterase
ANH9381_0018	COG1294	oxidase, subunit
ANH9381_0025	COG0641	radical SAM
ANH9381_0026	COG0217	transcriptional regulatory protein
ANH9381_0027	COG0494	nUDIX hydrolase
ANH9381_0030	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANH9381_0031	COG1755	Isoprenylcysteine carboxyl methyltransferase
ANH9381_0040	COG0346	lactoylglutathione lyase activity
ANH9381_0041	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANH9381_0043	COG2056	Na+-H+ antiporter family
ANH9381_0047	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANH9381_0048	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANH9381_0049	COG0142	geranyltranstransferase activity
ANH9381_0052	COG0697	spore germination
ANH9381_0053	COG0697	spore germination
ANH9381_0054	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANH9381_0058	COG4166	transmembrane transport
ANH9381_0059	COG0601	transmembrane transport
ANH9381_0060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANH9381_0061	COG0444	Belongs to the ABC transporter superfamily
ANH9381_0062	COG4608	Belongs to the ABC transporter superfamily
ANH9381_0063	COG0745	RESPONSE REGULATOR receiver
ANH9381_0064	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ANH9381_0066	COG1611	Belongs to the LOG family
ANH9381_0068	COG2259	Doxx family
ANH9381_0075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANH9381_0076	COG0626	cystathionine gamma-synthase activity
ANH9381_0081	COG2948	multi-organism process
ANH9381_0092	COG2860	membrane
ANH9381_0096	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANH9381_0098	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ANH9381_0099	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ANH9381_0100	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ANH9381_0101	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ANH9381_0103	COG0560	Phosphoserine phosphatase
ANH9381_0107	COG0728	peptidoglycan biosynthetic process
ANH9381_0108	COG0196	riboflavin kinase activity
ANH9381_0111	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANH9381_0113	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANH9381_0114	COG4974	Belongs to the 'phage' integrase family
ANH9381_0115	COG2814	Major facilitator Superfamily
ANH9381_0117	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ANH9381_0120	COG3266	domain, Protein
ANH9381_0120	COG3061	Opacity-associated protein A
ANH9381_0121	COG1509	lysine 2,3-aminomutase activity
ANH9381_0123	COG3033	Beta-eliminating lyase
ANH9381_0124	COG0814	amino acid
ANH9381_0127	COG5413	integral membrane protein
ANH9381_0129	COG0204	Acyl-transferase
ANH9381_0133	COG0697	spore germination
ANH9381_0134	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANH9381_0135	COG1882	Formate acetyltransferase
ANH9381_0136	COG2116	formate transmembrane transporter activity
ANH9381_0137	COG0537	adenosine 5'-monophosphoramidase activity
ANH9381_0145	COG3022	response to hydroperoxide
ANH9381_0146	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ANH9381_0149	COG0681	Belongs to the peptidase S26 family
ANH9381_0155	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ANH9381_0156	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANH9381_0157	COG0592	DNA-directed DNA polymerase activity
ANH9381_0159	COG2226	methyltransferase
ANH9381_0162	COG2801	Transposase and inactivated derivatives
ANH9381_0164	COG0281	malic enzyme
ANH9381_0165	COG2081	HI0933 family
ANH9381_0166	COG3088	subunit of a heme lyase
ANH9381_0166	COG4235	cytochrome complex assembly
ANH9381_0167	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANH9381_0168	COG1138	Cytochrome C-type biogenesis protein
ANH9381_0170	COG3301	Polysulphide reductase, NrfD
ANH9381_0171	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_0172	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ANH9381_0180	COG1138	Cytochrome C-type biogenesis protein
ANH9381_0182	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANH9381_0183	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANH9381_0184	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANH9381_0185	COG4133	protoheme IX ABC transporter activity
ANH9381_0187	COG2814	Major facilitator Superfamily
ANH9381_0190	COG0281	malic enzyme
ANH9381_0190	COG0280	phosphate acetyltransferase
ANH9381_0193	COG2321	neutral zinc metallopeptidase
ANH9381_0196	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ANH9381_0197	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ANH9381_0199	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ANH9381_0202	COG0436	Aminotransferase
ANH9381_0204	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ANH9381_0205	COG2267	carboxylic ester hydrolase activity
ANH9381_0208	COG3091	SprT-like family
ANH9381_0209	COG0814	amino acid
ANH9381_0210	COG1760	l-serine dehydratase
ANH9381_0211	COG0252	asparaginase activity
ANH9381_0213	COG3063	Type IV pilus biogenesis stability protein PilW
ANH9381_0214	COG1426	Protein conserved in bacteria
ANH9381_0217	COG2976	Protein conserved in bacteria
ANH9381_0219	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANH9381_0221	COG2233	PERMEase
ANH9381_0222	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANH9381_0223	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANH9381_0224	COG2918	glutathione biosynthetic process
ANH9381_0224	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANH9381_0226	COG2194	sulfuric ester hydrolase activity
ANH9381_0227	COG0740	serine-type endopeptidase activity
ANH9381_0231	COG3739	integral membrane protein
ANH9381_0232	COG2217	Heavy metal translocating P-type atpase
ANH9381_0233	COG2608	mercury ion transmembrane transporter activity
ANH9381_0234	COG0789	Transcriptional regulator
ANH9381_0235	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ANH9381_0239	COG1720	tRNA m6t6A37 methyltransferase activity
ANH9381_0240	COG1575	Belongs to the MenA family. Type 1 subfamily
ANH9381_0242	COG0471	metal ion transport
ANH9381_0243	COG3028	Belongs to the UPF0307 family
ANH9381_0244	COG0312	modulator of DNA gyrase
ANH9381_0245	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ANH9381_0246	COG1929	Belongs to the glycerate kinase type-1 family
ANH9381_0247	COG2610	gluconate transmembrane transporter activity
ANH9381_0248	COG3835	regulator
ANH9381_0250	COG0513	Belongs to the DEAD box helicase family
ANH9381_0251	COG4785	May be involved in cell division
ANH9381_0254	COG2731	YhcH YjgK YiaL family protein
ANH9381_0255	COG3023	N-Acetylmuramoyl-L-alanine amidase
ANH9381_0256	COG4969	Belongs to the N-Me-Phe pilin family
ANH9381_0260	COG1459	type II secretion system
ANH9381_0263	COG0237	dephospho-CoA kinase activity
ANH9381_0263	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ANH9381_0264	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ANH9381_0266	COG1115	amino acid carrier protein
ANH9381_0267	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ANH9381_0268	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ANH9381_0273	COG2184	nucleotidyltransferase activity
ANH9381_0274	COG4145	pantothenate transmembrane transporter activity
ANH9381_0275	COG3924	membrane
ANH9381_0278	COG0439	Biotin carboxylase
ANH9381_0279	COG0511	ligase activity, forming carbon-carbon bonds
ANH9381_0284	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ANH9381_0286	COG0456	acetyltransferase
ANH9381_0287	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANH9381_0289	COG3078	GTPase activator activity
ANH9381_0290	COG0590	tRNA wobble adenosine to inosine editing
ANH9381_0291	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ANH9381_0293	COG0730	response to heat
ANH9381_0295	COG1869	D-ribose catabolic process
ANH9381_0297	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_0298	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_0299	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANH9381_0300	COG1278	Cold shock
ANH9381_0304	COG0165	Argininosuccinate lyase
ANH9381_0305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANH9381_0306	COG0753	catalase activity
ANH9381_0308	COG0587	DNA-directed DNA polymerase activity
ANH9381_0309	COG1022	Amp-dependent synthetase and ligase
ANH9381_0312	COG1328	CTP reductase activity
ANH9381_0312	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANH9381_0313	COG0602	queuosine metabolic process
ANH9381_0314	COG0084	hydrolase, TatD family'
ANH9381_0317	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANH9381_0322	COG1686	Belongs to the peptidase S11 family
ANH9381_0323	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANH9381_0323	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANH9381_0324	COG0772	Belongs to the SEDS family
ANH9381_0325	COG0768	penicillin binding
ANH9381_0327	COG0799	negative regulation of ribosome biogenesis
ANH9381_0328	COG0513	Belongs to the DEAD box helicase family
ANH9381_0329	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANH9381_0330	COG2814	Major facilitator Superfamily
ANH9381_0332	COG1028	Short-chain dehydrogenase reductase Sdr
ANH9381_0333	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANH9381_0337	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANH9381_0338	COG1399	metal-binding, possibly nucleic acid-binding protein
ANH9381_0340	COG0500	methyltransferase
ANH9381_0341	COG2830	Protein of unknown function (DUF452)
ANH9381_0343	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANH9381_0344	COG0688	phosphatidylethanolamine metabolic process
ANH9381_0345	COG0545	Peptidyl-prolyl cis-trans isomerase
ANH9381_0349	COG2966	Psort location CytoplasmicMembrane, score
ANH9381_0350	COG3610	response to peptide
ANH9381_0351	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ANH9381_0352	COG1253	flavin adenine dinucleotide binding
ANH9381_0355	COG0084	hydrolase, TatD family'
ANH9381_0356	COG0470	DNA polymerase III
ANH9381_0357	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANH9381_0358	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANH9381_0359	COG0347	Belongs to the P(II) protein family
ANH9381_0360	COG1349	DNA-binding transcription factor activity
ANH9381_0361	COG2084	Dehydrogenase
ANH9381_0362	COG3395	kinase activity
ANH9381_0363	COG0235	Class ii aldolase
ANH9381_0364	COG3622	Belongs to the hyi family
ANH9381_0365	COG2610	gluconate transmembrane transporter activity
ANH9381_0367	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ANH9381_0370	COG0561	phosphatase activity
ANH9381_0375	COG3085	chromosome segregation
ANH9381_0376	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANH9381_0377	COG3084	Protein conserved in bacteria
ANH9381_0378	COG0746	molybdenum cofactor guanylyltransferase activity
ANH9381_0380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_0380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_0381	COG1105	Belongs to the carbohydrate kinase PfkB family
ANH9381_0382	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANH9381_0382	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ANH9381_0382	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANH9381_0389	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ANH9381_0393	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ANH9381_0397	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ANH9381_0398	COG0255	Belongs to the universal ribosomal protein uL29 family
ANH9381_0399	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANH9381_0400	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ANH9381_0401	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANH9381_0402	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ANH9381_0403	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANH9381_0404	COG0089	rRNA binding
ANH9381_0405	COG0088	Forms part of the polypeptide exit tunnel
ANH9381_0406	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANH9381_0407	COG0051	transcription antitermination factor activity, RNA binding
ANH9381_0408	COG0583	DNA-binding transcription factor activity
ANH9381_0409	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ANH9381_0410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ANH9381_0411	COG2031	fatty acid transporter
ANH9381_0412	COG0183	Belongs to the thiolase family
ANH9381_0414	COG1288	antiporter activity
ANH9381_0415	COG0549	Belongs to the carbamate kinase family
ANH9381_0416	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANH9381_0417	COG0038	chloride channel
ANH9381_0418	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANH9381_0420	COG1522	sequence-specific DNA binding
ANH9381_0421	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ANH9381_0423	COG1393	Belongs to the ArsC family
ANH9381_0425	COG3036	rescue of stalled ribosome
ANH9381_0426	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANH9381_0427	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANH9381_0428	COG2841	Protein conserved in bacteria
ANH9381_0431	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ANH9381_0433	COG0569	domain protein
ANH9381_0442	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ANH9381_0446	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ANH9381_0447	COG2990	Protein conserved in bacteria
ANH9381_0449	COG0606	chelatase, subunit chli
ANH9381_0452	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ANH9381_0455	COG3501	Rhs element vgr protein
ANH9381_0466	COG0606	chelatase, subunit chli
ANH9381_0467	COG2861	carbohydrate metabolic process
ANH9381_0468	COG4942	peptidase
ANH9381_0469	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANH9381_0474	COG2853	Lipoprotein
ANH9381_0475	COG0747	negative chemotaxis
ANH9381_0481	COG0814	amino acid
ANH9381_0483	COG4783	chaperone-mediated protein folding
ANH9381_0484	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANH9381_0486	COG0552	protein localization to endoplasmic reticulum
ANH9381_0487	COG0742	ribosomal rna small subunit methyltransferase
ANH9381_0488	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANH9381_0488	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_0489	COG3715	PTS system
ANH9381_0490	COG3716	PTS system mannose fructose sorbose family IID component
ANH9381_0491	COG0561	phosphatase activity
ANH9381_0492	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ANH9381_0498	COG1215	transferase activity, transferring glycosyl groups
ANH9381_0501	COG2271	Major facilitator Superfamily
ANH9381_0507	COG0513	Belongs to the DEAD box helicase family
ANH9381_0510	COG3201	nicotinamide mononucleotide transporter
ANH9381_0513	COG1238	metal cluster binding
ANH9381_0514	COG0110	maltose O-acetyltransferase activity
ANH9381_0515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANH9381_0520	COG0210	DNA helicase
ANH9381_0521	COG5645	(Lipo)protein
ANH9381_0523	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANH9381_0523	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANH9381_0530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANH9381_0532	COG0859	PFAM glycosyl transferase family 9
ANH9381_0535	COG3005	denitrification pathway
ANH9381_0536	COG3043	anaerobic respiration
ANH9381_0537	COG0348	domain, Protein
ANH9381_0538	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_0539	COG0243	molybdopterin cofactor binding
ANH9381_0540	COG3062	negative regulation of establishment of protein localization
ANH9381_0542	COG3850	Histidine kinase
ANH9381_0543	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANH9381_0545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANH9381_0548	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANH9381_0551	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANH9381_0553	COG0583	DNA-binding transcription factor activity
ANH9381_0554	COG2962	Rard protein
ANH9381_0557	COG0551	DNA topoisomerase type I activity
ANH9381_0562	COG0705	Rhomboid family
ANH9381_0563	COG1349	DNA-binding transcription factor activity
ANH9381_0565	COG4178	(ABC) transporter
ANH9381_0570	COG0233	cytoplasmic translational termination
ANH9381_0573	COG0575	Belongs to the CDS family
ANH9381_0576	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ANH9381_0578	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANH9381_0580	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANH9381_0582	COG0490	domain, Protein
ANH9381_0582	COG0471	metal ion transport
ANH9381_0583	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANH9381_0585	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANH9381_0592	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANH9381_0594	COG0251	oxidation-reduction process
ANH9381_0595	COG2137	regulation of response to DNA damage stimulus
ANH9381_0596	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANH9381_0599	COG2095	MarC family integral membrane protein
ANH9381_0602	COG0582	viral genome integration into host DNA
ANH9381_0603	COG2963	transposase activity
ANH9381_0605	COG1349	DNA-binding transcription factor activity
ANH9381_0607	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANH9381_0609	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ANH9381_0614	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANH9381_0615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANH9381_0616	COG0765	amino acid transport
ANH9381_0617	COG1126	abc transporter atp-binding protein
ANH9381_0618	COG2168	tRNA wobble position uridine thiolation
ANH9381_0620	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ANH9381_0621	COG2964	Protein conserved in bacteria
ANH9381_0622	COG0545	Peptidyl-prolyl cis-trans isomerase
ANH9381_0623	COG2900	Belongs to the SlyX family
ANH9381_0624	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANH9381_0624	COG0678	peroxiredoxin activity
ANH9381_0625	COG0583	DNA-binding transcription factor activity
ANH9381_0626	COG1309	transcriptional regulator
ANH9381_0627	COG1132	(ABC) transporter
ANH9381_0628	COG4988	ABC transporter
ANH9381_0629	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ANH9381_0630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANH9381_0631	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ANH9381_0633	COG1045	serine acetyltransferase
ANH9381_0634	COG1494	fructose-1,6-bisphosphatase
ANH9381_0636	COG0716	FMN binding
ANH9381_0638	COG0702	epimerase
ANH9381_0639	COG1733	regulation of RNA biosynthetic process
ANH9381_0641	COG3312	ion transport
ANH9381_0645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANH9381_0647	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANH9381_0650	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ANH9381_0654	COG0732	type I restriction modification DNA specificity domain
ANH9381_0656	COG3716	PTS system mannose fructose sorbose family IID component
ANH9381_0657	COG3715	PTS system
ANH9381_0658	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANH9381_0658	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_0660	COG2814	Major facilitator Superfamily
ANH9381_0661	COG2207	Transcriptional regulator
ANH9381_0661	COG1609	Transcriptional regulator
ANH9381_0662	COG1757	Na H antiporter
ANH9381_0663	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ANH9381_0664	COG4214	carbohydrate transport
ANH9381_0665	COG1129	ABC transporter
ANH9381_0666	COG4213	ABC transporter substrate-binding protein
ANH9381_0667	COG2115	Belongs to the xylose isomerase family
ANH9381_0668	COG1070	Carbohydrate kinase
ANH9381_0671	COG2801	Transposase and inactivated derivatives
ANH9381_0672	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANH9381_0673	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANH9381_0674	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANH9381_0675	COG3719	Belongs to the RNase T2 family
ANH9381_0677	COG0191	fructose-bisphosphate aldolase activity
ANH9381_0679	COG3307	-O-antigen
ANH9381_0680	COG2267	carboxylic ester hydrolase activity
ANH9381_0681	COG0561	phosphatase activity
ANH9381_0683	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANH9381_0684	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANH9381_0685	COG2177	Part of the ABC transporter FtsEX involved in
ANH9381_0686	COG2884	Cell division ATP-binding protein ftsE
ANH9381_0688	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANH9381_0694	COG1238	metal cluster binding
ANH9381_0696	COG1388	LysM domain
ANH9381_0696	COG4942	peptidase
ANH9381_0698	COG0463	Glycosyl transferase, family 2
ANH9381_0699	COG1519	Transferase
ANH9381_0702	COG0859	PFAM glycosyl transferase family 9
ANH9381_0703	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ANH9381_0704	COG1917	Cupin 2, conserved barrel domain protein
ANH9381_0704	COG4977	sequence-specific DNA binding
ANH9381_0705	COG1132	(ABC) transporter
ANH9381_0712	COG0758	DNA mediated transformation
ANH9381_0713	COG0584	glycerophosphoryl diester phosphodiesterase
ANH9381_0714	COG2271	Major facilitator Superfamily
ANH9381_0717	COG0557	exoribonuclease II activity
ANH9381_0718	COG1077	Cell shape determining protein MreB Mrl
ANH9381_0719	COG1792	Involved in formation and maintenance of cell shape
ANH9381_0720	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ANH9381_0725	COG0006	proline dipeptidase activity
ANH9381_0728	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ANH9381_0734	COG0778	Nitroreductase
ANH9381_0736	COG0762	integral membrane protein
ANH9381_0739	COG0500	methyltransferase
ANH9381_0740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANH9381_0741	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_0742	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANH9381_0743	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ANH9381_0746	COG3306	glycosyltransferase involved in LPS biosynthesis
ANH9381_0749	COG3306	glycosyltransferase involved in LPS biosynthesis
ANH9381_0754	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ANH9381_0757	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANH9381_0759	COG1309	transcriptional regulator
ANH9381_0762	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANH9381_0763	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ANH9381_0764	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANH9381_0765	COG4972	Pilus assembly protein
ANH9381_0769	COG4796	Type ii and iii secretion system protein
ANH9381_0772	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ANH9381_0774	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ANH9381_0776	COG2801	Transposase and inactivated derivatives
ANH9381_0780	COG0459	protein refolding
ANH9381_0782	COG1027	Aspartate ammonia-lyase
ANH9381_0783	COG0859	PFAM glycosyl transferase family 9
ANH9381_0785	COG2801	Transposase and inactivated derivatives
ANH9381_0787	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ANH9381_0797	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ANH9381_0798	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANH9381_0800	COG1739	Uncharacterized protein family UPF0029
ANH9381_0802	COG3172	ATPase kinase involved in NAD metabolism
ANH9381_0803	COG2129	metallophosphoesterase
ANH9381_0804	COG0814	amino acid
ANH9381_0805	COG1943	Transposase
ANH9381_0808	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ANH9381_0812	COG0201	protein transport
ANH9381_0814	COG1841	ribosomal large subunit assembly
ANH9381_0816	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ANH9381_0818	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANH9381_0820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANH9381_0822	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ANH9381_0824	COG1943	Transposase
ANH9381_0826	COG1114	Component of the transport system for branched-chain amino acids
ANH9381_0829	COG1040	competence protein
ANH9381_0830	COG0561	phosphatase activity
ANH9381_0831	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANH9381_0832	COG1596	polysaccharide export
ANH9381_0832	COG1555	photosystem II stabilization
ANH9381_0837	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANH9381_0838	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ANH9381_0840	COG1011	Hydrolase
ANH9381_0845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANH9381_0856	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANH9381_0858	COG1028	Short-chain dehydrogenase reductase Sdr
ANH9381_0859	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANH9381_0862	COG4545	Glutaredoxin-related protein
ANH9381_0863	COG1794	racemase activity, acting on amino acids and derivatives
ANH9381_0866	COG0363	glucosamine-6-phosphate deaminase activity
ANH9381_0867	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANH9381_0868	COG1218	3'(2'),5'-bisphosphate nucleotidase
ANH9381_0870	COG1297	OPT oligopeptide transporter protein
ANH9381_0871	COG3059	membrane
ANH9381_0872	COG4977	sequence-specific DNA binding
ANH9381_0872	COG1917	Cupin 2, conserved barrel domain protein
ANH9381_0873	COG0494	nUDIX hydrolase
ANH9381_0874	COG1011	Hydrolase
ANH9381_0875	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ANH9381_0876	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANH9381_0877	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANH9381_0878	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANH9381_0879	COG0805	protein transport
ANH9381_0884	COG4545	Glutaredoxin-related protein
ANH9381_0886	COG2221	Nitrite and sulphite reductase 4Fe-4S
ANH9381_0886	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANH9381_0887	COG3381	protein complex oligomerization
ANH9381_0888	COG3302	dmso reductase anchor subunit
ANH9381_0889	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_0890	COG0243	molybdopterin cofactor binding
ANH9381_0899	COG0848	biopolymer transport protein
ANH9381_0900	COG0811	peptide transport
ANH9381_0901	COG4536	flavin adenine dinucleotide binding
ANH9381_0904	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANH9381_0907	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ANH9381_0908	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANH9381_0909	COG0789	Transcriptional regulator
ANH9381_0910	COG0789	Transcriptional regulator
ANH9381_0911	COG4221	oxidoreductase activity
ANH9381_0913	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANH9381_0917	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANH9381_0918	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANH9381_0919	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANH9381_0927	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ANH9381_0928	COG1466	dna polymerase III delta subunit
ANH9381_0929	COG0494	nUDIX hydrolase
ANH9381_0933	COG4701	Protein of unknown function (DUF721)
ANH9381_0934	COG0789	Transcriptional regulator
ANH9381_0935	COG2801	Transposase and inactivated derivatives
ANH9381_0937	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ANH9381_0938	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANH9381_0939	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANH9381_0940	COG1381	Involved in DNA repair and RecF pathway recombination
ANH9381_0941	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANH9381_0944	COG0354	folic acid binding
ANH9381_0945	COG1561	YicC-like family, N-terminal region
ANH9381_0947	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANH9381_0952	COG3842	ATPase activity
ANH9381_0953	COG1178	ABC-type Fe3 transport system permease component
ANH9381_0954	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_0955	COG3171	Protein conserved in bacteria
ANH9381_0957	COG1194	a g-specific adenine glycosylase
ANH9381_0958	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ANH9381_0962	COG3056	Lipoprotein
ANH9381_0963	COG0271	Belongs to the BolA IbaG family
ANH9381_0968	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ANH9381_0969	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ANH9381_0970	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ANH9381_0971	COG2871	sodium ion transport
ANH9381_0973	COG1477	protein flavinylation
ANH9381_0974	COG2991	Protein conserved in bacteria
ANH9381_0977	COG0148	phosphopyruvate hydratase activity
ANH9381_0980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ANH9381_0982	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ANH9381_0983	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ANH9381_0984	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANH9381_0985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ANH9381_0988	COG0589	response to stress
ANH9381_0989	COG3956	TIGRFAM MazG family protein
ANH9381_0990	COG0402	S-adenosylhomocysteine deaminase activity
ANH9381_0991	COG3083	sulfuric ester hydrolase activity
ANH9381_0992	COG3082	Protein of unknown function (DUF1414)
ANH9381_0994	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANH9381_0995	COG0745	RESPONSE REGULATOR receiver
ANH9381_0996	COG2205	protein histidine kinase activity
ANH9381_0997	COG0786	glutamate:sodium symporter activity
ANH9381_1000	COG3012	SEC-C Motif Domain Protein
ANH9381_1001	COG2258	MOSC domain
ANH9381_1002	COG0433	COG0433 Predicted ATPase
ANH9381_1005	COG0656	L-ascorbic acid biosynthetic process
ANH9381_1006	COG0667	Aldo Keto reductase
ANH9381_1013	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ANH9381_1014	COG1349	DNA-binding transcription factor activity
ANH9381_1016	COG3068	Protein conserved in bacteria
ANH9381_1017	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ANH9381_1021	COG0248	Ppx GppA phosphatase
ANH9381_1022	COG2911	Protein conserved in bacteria
ANH9381_1023	COG0729	surface antigen
ANH9381_1024	COG2197	response regulator
ANH9381_1026	COG0181	hydroxymethylbilane synthase activity
ANH9381_1028	COG2959	enzyme of heme biosynthesis
ANH9381_1029	COG3071	HemY protein
ANH9381_1030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ANH9381_1032	COG1595	DNA-templated transcription, initiation
ANH9381_1034	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANH9381_1035	COG2183	response to ionizing radiation
ANH9381_1036	COG0588	phosphoglycerate mutase activity
ANH9381_1037	COG0471	metal ion transport
ANH9381_1038	COG0583	DNA-binding transcription factor activity
ANH9381_1039	COG2183	response to ionizing radiation
ANH9381_1041	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_1042	COG1129	ABC transporter
ANH9381_1043	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_1044	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANH9381_1049	COG1072	(Pantothenic acid kinase))
ANH9381_1050	COG0187	DNA topoisomerase II activity
ANH9381_1051	COG0514	ATP-dependent DNA helicase (RecQ)
ANH9381_1054	COG0019	diaminopimelate decarboxylase activity
ANH9381_1055	COG3477	response to acidic pH
ANH9381_1056	COG2818	Glycosylase
ANH9381_1057	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ANH9381_1059	COG2195	Cleaves the N-terminal amino acid of tripeptides
ANH9381_1060	COG0300	oxidoreductase activity
ANH9381_1061	COG1763	Mo-molybdopterin cofactor biosynthetic process
ANH9381_1062	COG3086	response to oxidative stress
ANH9381_1063	COG3026	antisigma factor binding
ANH9381_1064	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ANH9381_1065	COG1595	DNA-templated transcription, initiation
ANH9381_1068	COG0442	prolyl-tRNA aminoacylation
ANH9381_1069	COG1921	L-seryl-tRNASec selenium transferase activity
ANH9381_1070	COG3276	selenocysteine insertion sequence binding
ANH9381_1072	COG1285	pathogenesis
ANH9381_1074	COG0733	neurotransmitter:sodium symporter activity
ANH9381_1087	COG4964	Belongs to the GSP D family
ANH9381_1092	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANH9381_1094	COG1444	tRNA N-acetyltransferase activity
ANH9381_1096	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANH9381_1098	COG1126	abc transporter atp-binding protein
ANH9381_1099	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANH9381_1100	COG4215	(ABC) transporter
ANH9381_1101	COG4160	amino acid transport
ANH9381_1102	COG1966	Carbon starvation protein
ANH9381_1105	COG3116	cell division
ANH9381_1106	COG0768	penicillin binding
ANH9381_1108	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANH9381_1110	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANH9381_1112	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANH9381_1115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ANH9381_1116	COG0849	cell division
ANH9381_1117	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANH9381_1119	COG0077	Prephenate dehydratase
ANH9381_1119	COG1605	Chorismate mutase
ANH9381_1120	COG0326	Molecular chaperone. Has ATPase activity
ANH9381_1121	COG1393	Belongs to the ArsC family
ANH9381_1123	COG1876	peptidase activity
ANH9381_1124	COG0494	nUDIX hydrolase
ANH9381_1125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ANH9381_1134	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ANH9381_1136	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ANH9381_1137	COG1053	succinate dehydrogenase
ANH9381_1140	COG1120	ATPase activity
ANH9381_1141	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_1142	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_1143	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ANH9381_1144	COG1408	metallophosphoesterase
ANH9381_1146	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANH9381_1147	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANH9381_1152	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANH9381_1154	COG0741	lytic transglycosylase activity
ANH9381_1155	COG2350	Protein conserved in bacteria
ANH9381_1156	COG1607	acyl-coa hydrolase
ANH9381_1157	COG2917	probably involved in intracellular septation
ANH9381_1160	COG3047	cAMP biosynthetic process
ANH9381_1161	COG0497	DNA recombination
ANH9381_1163	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANH9381_1166	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANH9381_1166	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ANH9381_1167	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANH9381_1168	COG2198	Histidine kinase
ANH9381_1168	COG5002	protein histidine kinase activity
ANH9381_1168	COG0784	Response regulator, receiver
ANH9381_1169	COG4211	Belongs to the binding-protein-dependent transport system permease family
ANH9381_1172	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_1173	COG1609	Transcriptional regulator
ANH9381_1174	COG1085	galactose-1-phosphate uridylyltransferase
ANH9381_1175	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ANH9381_1176	COG2017	converts alpha-aldose to the beta-anomer
ANH9381_1179	COG0471	metal ion transport
ANH9381_1180	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
ANH9381_1180	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ANH9381_1181	COG3051	citrate lyase alpha subunit
ANH9381_1182	COG2301	Belongs to the HpcH HpaI aldolase family
ANH9381_1184	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ANH9381_1186	COG4535	Mg2 and Co2 transporter CorC
ANH9381_1190	COG0105	UTP biosynthetic process
ANH9381_1192	COG0489	protein tyrosine kinase activity
ANH9381_1193	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANH9381_1193	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANH9381_1194	COG2975	iron-sulfur cluster assembly
ANH9381_1195	COG0633	Ferredoxin
ANH9381_1196	COG0443	Heat shock 70 kDa protein
ANH9381_1199	COG0822	iron-sulfur transferase activity
ANH9381_1201	COG1959	2 iron, 2 sulfur cluster binding
ANH9381_1202	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ANH9381_1207	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_1208	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_1218	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANH9381_1219	COG1530	ribonuclease E activity
ANH9381_1220	COG2999	glutathione oxidoreductase activity
ANH9381_1221	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ANH9381_1233	COG3021	interspecies interaction between organisms
ANH9381_1240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANH9381_1241	COG0626	cystathionine gamma-synthase activity
ANH9381_1244	COG2337	Toxic component of a toxin-antitoxin (TA) module
ANH9381_1245	COG0484	heat shock protein binding
ANH9381_1248	COG5339	Protein conserved in bacteria
ANH9381_1250	COG3102	Protein conserved in bacteria
ANH9381_1251	COG3133	Outer membrane lipoprotein
ANH9381_1252	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANH9381_1253	COG2890	protein-(glutamine-N5) methyltransferase activity
ANH9381_1255	COG0791	NLP P60 protein
ANH9381_1256	COG3100	YcgL domain-containing protein
ANH9381_1259	COG2062	phosphohistidine phosphatase, SixA
ANH9381_1261	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANH9381_1262	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANH9381_1263	COG2801	Transposase and inactivated derivatives
ANH9381_1265	COG0529	Catalyzes the synthesis of activated sulfate
ANH9381_1267	COG2963	transposase activity
ANH9381_1268	COG0517	IMP dehydrogenase activity
ANH9381_1268	COG0516	GMP reductase activity
ANH9381_1269	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ANH9381_1269	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ANH9381_1276	COG4172	Belongs to the ABC transporter superfamily
ANH9381_1277	COG4172	Belongs to the ABC transporter superfamily
ANH9381_1278	COG4171	peptide transport system, permease
ANH9381_1279	COG4168	peptide transport system, permease
ANH9381_1280	COG4166	transmembrane transport
ANH9381_1281	COG3106	COG3106 Predicted ATPase
ANH9381_1283	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ANH9381_1286	COG1923	regulation of RNA biosynthetic process
ANH9381_1288	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ANH9381_1289	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANH9381_1289	COG1388	LysM domain
ANH9381_1290	COG0802	atpase or kinase
ANH9381_1292	COG2246	polysaccharide biosynthetic process
ANH9381_1295	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ANH9381_1302	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_1303	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANH9381_1304	COG2190	(PTS) system
ANH9381_1305	COG0339	signal peptide processing
ANH9381_1306	COG2832	Protein of unknown function (DUF454)
ANH9381_1310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANH9381_1312	COG0512	Glutamine amidotransferase of anthranilate synthase
ANH9381_1313	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANH9381_1314	COG4591	ABC-type transport system involved in lipoprotein release permease component
ANH9381_1316	COG4591	ABC-type transport system involved in lipoprotein release permease component
ANH9381_1317	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANH9381_1319	COG0305	Participates in initiation and elongation during chromosome replication
ANH9381_1321	COG0166	Belongs to the GPI family
ANH9381_1322	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ANH9381_1324	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ANH9381_1325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ANH9381_1326	COG1280	lysine exporter protein (LysE YggA)
ANH9381_1328	COG0633	Ferredoxin
ANH9381_1330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANH9381_1331	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANH9381_1334	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_1336	COG3842	ATPase activity
ANH9381_1337	COG0366	Alpha amylase catalytic
ANH9381_1338	COG3833	ABC-type maltose transport systems, permease component
ANH9381_1340	COG2182	Extracellular solute-binding protein
ANH9381_1341	COG3842	ATPase activity
ANH9381_1342	COG4580	involved in the transport of maltose and maltodextrins
ANH9381_1345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANH9381_1346	COG0303	'Molybdopterin
ANH9381_1348	COG2027	D-alanyl-D-alanine carboxypeptidase
ANH9381_1349	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANH9381_1350	COG1534	Rna-binding protein
ANH9381_1351	COG3657	addiction module killer protein
ANH9381_1352	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ANH9381_1353	COG0307	riboflavin synthase, alpha
ANH9381_1355	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ANH9381_1356	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANH9381_1357	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANH9381_1358	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ANH9381_1359	COG3842	ATPase activity
ANH9381_1360	COG0157	Belongs to the NadC ModD family
ANH9381_1363	COG2855	membrane
ANH9381_1364	COG4953	penicillin-binding protein 1C
ANH9381_1365	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ANH9381_1370	COG3623	hexulose-6-phosphate isomerase
ANH9381_1371	COG0235	Class ii aldolase
ANH9381_1372	COG0814	amino acid
ANH9381_1374	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANH9381_1375	COG0778	Nitroreductase
ANH9381_1380	COG0114	fumarate hydratase activity
ANH9381_1381	COG2927	DNA polymerase III (CHI subunit)
ANH9381_1391	COG2814	Major facilitator Superfamily
ANH9381_1392	COG1566	PFAM secretion protein HlyD family protein
ANH9381_1394	COG0783	Belongs to the Dps family
ANH9381_1396	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANH9381_1397	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ANH9381_1398	COG0602	queuosine metabolic process
ANH9381_1399	COG0720	synthase
ANH9381_1400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ANH9381_1402	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANH9381_1403	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANH9381_1404	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANH9381_1405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ANH9381_1406	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ANH9381_1407	COG0310	cobalt ion transport
ANH9381_1408	COG0310	cobalt ion transport
ANH9381_1409	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ANH9381_1410	COG1122	ATPase activity
ANH9381_1411	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANH9381_1412	COG0409	Hydrogenase expression formation protein
ANH9381_1413	COG0309	Hydrogenase expression formation protein (HypE)
ANH9381_1415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ANH9381_1416	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ANH9381_1417	COG0795	lipopolysaccharide-transporting ATPase activity
ANH9381_1418	COG0795	lipopolysaccharide-transporting ATPase activity
ANH9381_1419	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANH9381_1420	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ANH9381_1421	COG4149	molybdate abc transporter
ANH9381_1422	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANH9381_1423	COG2005	Transcriptional regulator
ANH9381_1424	COG0471	metal ion transport
ANH9381_1426	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANH9381_1427	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANH9381_1427	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANH9381_1428	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANH9381_1430	COG0583	DNA-binding transcription factor activity
ANH9381_1431	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANH9381_1433	COG0039	L-malate dehydrogenase activity
ANH9381_1434	COG1438	arginine binding
ANH9381_1435	COG1090	epimerase
ANH9381_1436	COG4657	Part of a membrane complex involved in electron transport
ANH9381_1443	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANH9381_1444	COG0733	neurotransmitter:sodium symporter activity
ANH9381_1445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANH9381_1447	COG0739	heme binding
ANH9381_1448	COG4604	ABC transporter, ATP-binding protein
ANH9381_1449	COG4605	iron ion homeostasis
ANH9381_1450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANH9381_1451	COG4607	ABC-type enterochelin transport system periplasmic component
ANH9381_1455	COG3111	PFAM Bacterial OB fold (BOF) protein
ANH9381_1460	COG3392	D12 class N6 adenine-specific DNA methyltransferase
ANH9381_1461	COG0745	RESPONSE REGULATOR receiver
ANH9381_1462	COG0642	Histidine kinase
ANH9381_1463	COG0405	Gamma-glutamyltransferase
ANH9381_1466	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANH9381_1467	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ANH9381_1468	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
ANH9381_1473	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANH9381_1474	COG1518	maintenance of DNA repeat elements
ANH9381_1476	COG0351	phosphomethylpyrimidine kinase
ANH9381_1477	COG4143	(ABC) transporter
ANH9381_1478	COG1178	ABC-type Fe3 transport system permease component
ANH9381_1479	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ANH9381_1481	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANH9381_1482	COG3105	Protein conserved in bacteria
ANH9381_1486	COG3422	double-strand break repair
ANH9381_1489	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANH9381_1491	COG1940	carbohydrate kinase activity
ANH9381_1491	COG1846	Transcriptional regulator
ANH9381_1496	COG0563	adenylate kinase activity
ANH9381_1497	COG2814	Major facilitator Superfamily
ANH9381_1498	COG0375	protein maturation
ANH9381_1499	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANH9381_1500	COG3152	Membrane
ANH9381_1502	COG2252	PERMEase
ANH9381_1505	COG0825	malonyl-CoA metabolic process
ANH9381_1506	COG2351	hydroxyisourate hydrolase activity
ANH9381_1520	COG1598	PFAM Uncharacterised protein family UPF0150
ANH9381_1524	COG5301	cellulose 1,4-beta-cellobiosidase activity
ANH9381_1526	COG0582	viral genome integration into host DNA
ANH9381_1528	COG3041	Addiction module toxin RelE StbE family
ANH9381_1529	COG3077	Addiction module antitoxin, RelB DinJ family
ANH9381_1531	COG3069	C4-dicarboxylate transmembrane transporter activity
ANH9381_1534	COG0195	Participates in both transcription termination and antitermination
ANH9381_1542	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANH9381_1549	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ANH9381_1550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ANH9381_1551	COG3177	Filamentation induced by cAMP protein fic
ANH9381_1554	COG1175	transmembrane transport
ANH9381_1555	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANH9381_1557	COG0322	excinuclease ABC activity
ANH9381_1559	COG2835	tetraacyldisaccharide 4'-kinase activity
ANH9381_1560	COG1663	tetraacyldisaccharide 4'-kinase activity
ANH9381_1561	COG1132	(ABC) transporter
ANH9381_1562	COG2333	competence protein COMEC
ANH9381_1562	COG0658	competence protein
ANH9381_1563	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ANH9381_1564	COG0617	tRNA 3'-terminal CCA addition
ANH9381_1565	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANH9381_1568	COG0857	belongs to the CobB CobQ family
ANH9381_1568	COG0280	phosphate acetyltransferase
ANH9381_1569	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANH9381_1570	COG3092	negative regulation of chromosome organization
ANH9381_1571	COG1286	toxin biosynthetic process
ANH9381_1573	COG1640	4-alpha-glucanotransferase
ANH9381_1574	COG0058	SHG alpha-glucan phosphorylase activity
ANH9381_1575	COG2909	trisaccharide binding
ANH9381_1577	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ANH9381_1578	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANH9381_1579	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANH9381_1580	COG0778	Nitroreductase
ANH9381_1581	COG0616	signal peptide processing
ANH9381_1585	COG0009	L-threonylcarbamoyladenylate synthase
ANH9381_1587	COG0583	DNA-binding transcription factor activity
ANH9381_1589	COG3099	Belongs to the UPF0263 family
ANH9381_1592	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ANH9381_1593	COG2949	membrane
ANH9381_1594	COG1609	Transcriptional regulator
ANH9381_1597	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANH9381_1598	COG0785	Cytochrome C biogenesis protein
ANH9381_1599	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANH9381_1599	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANH9381_1600	COG0288	reversible hydration of carbon dioxide
ANH9381_1601	COG2823	Periplasmic or secreted lipoprotein
ANH9381_1602	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ANH9381_1603	COG0792	nuclease activity
ANH9381_1605	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANH9381_1610	COG0616	signal peptide processing
ANH9381_1611	COG2885	chlorophyll binding
ANH9381_1611	COG3047	cAMP biosynthetic process
ANH9381_1619	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ANH9381_1621	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ANH9381_1623	COG3684	Belongs to the aldolase LacD family
ANH9381_1625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_1626	COG3414	Phosphotransferase system galactitol-specific IIB component
ANH9381_1627	COG3775	system Galactitol-specific IIC component
ANH9381_1628	COG1063	alcohol dehydrogenase
ANH9381_1629	COG1349	DNA-binding transcription factor activity
ANH9381_1631	COG0142	geranyltranstransferase activity
ANH9381_1634	COG0285	dihydrofolate synthase activity
ANH9381_1635	COG0406	alpha-ribazole phosphatase activity
ANH9381_1636	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANH9381_1637	COG2431	L-lysine efflux transmembrane transporter activity
ANH9381_1638	COG0564	pseudouridine synthase activity
ANH9381_1640	COG2824	Alkylphosphonate utilization operon protein PhnA
ANH9381_1646	COG1538	Outer membrane efflux protein
ANH9381_1649	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_1654	COG1523	belongs to the glycosyl hydrolase 13 family
ANH9381_1657	COG0058	SHG alpha-glucan phosphorylase activity
ANH9381_1658	COG0586	Pfam SNARE associated Golgi protein
ANH9381_1659	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ANH9381_1661	COG1686	Belongs to the peptidase S11 family
ANH9381_1662	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ANH9381_1671	COG0697	spore germination
ANH9381_1672	COG2925	Exonuclease
ANH9381_1677	COG1528	Iron-storage protein
ANH9381_1678	COG1528	Iron-storage protein
ANH9381_1680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANH9381_1681	COG0589	response to stress
ANH9381_1682	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
ANH9381_1684	COG0613	PHP domain protein
ANH9381_1685	COG0167	dihydroorotate dehydrogenase activity
ANH9381_1686	COG0308	aminopeptidase N
ANH9381_1687	COG1448	Aminotransferase
ANH9381_1689	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_1690	COG0842	Transport permease protein
ANH9381_1690	COG1129	ABC transporter
ANH9381_1691	COG0842	Transport permease protein
ANH9381_1696	COG1120	ATPase activity
ANH9381_1698	COG3585	molybdate ion transport
ANH9381_1701	COG1120	ATPase activity
ANH9381_1704	COG4774	siderophore transport
ANH9381_1707	COG0791	NLP P60 protein
ANH9381_1710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANH9381_1712	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANH9381_1712	COG0517	IMP dehydrogenase activity
ANH9381_1713	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ANH9381_1714	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANH9381_1715	COG0512	Glutamine amidotransferase of anthranilate synthase
ANH9381_1716	COG1942	4-Oxalocrotonate Tautomerase
ANH9381_1717	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANH9381_1719	COG3093	addiction module antidote protein HigA
ANH9381_1720	COG0134	indole-3-glycerol-phosphate synthase activity
ANH9381_1720	COG0135	phosphoribosylanthranilate isomerase activity
ANH9381_1722	COG0298	carbon dioxide binding
ANH9381_1725	COG3630	sodium ion export across plasma membrane
ANH9381_1731	COG4221	oxidoreductase activity
ANH9381_1732	COG0133	tryptophan synthase activity
ANH9381_1734	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANH9381_1736	COG0469	pyruvate kinase activity
ANH9381_1739	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_1741	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_1745	COG2390	Transcriptional regulator
ANH9381_1747	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ANH9381_1748	COG1940	carbohydrate kinase activity
ANH9381_1750	COG2969	positive regulation of protein catabolic process
ANH9381_1752	COG0314	molybdopterin synthase activity
ANH9381_1753	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ANH9381_1755	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANH9381_1760	COG3005	denitrification pathway
ANH9381_1761	COG0243	molybdopterin cofactor binding
ANH9381_1762	COG2315	Protein conserved in bacteria
ANH9381_1763	COG0471	metal ion transport
ANH9381_1767	COG0101	tRNA pseudouridine synthase activity
ANH9381_1772	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ANH9381_1775	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ANH9381_1777	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANH9381_1778	COG1067	ATP-dependent peptidase activity
ANH9381_1780	COG1278	Cold shock
ANH9381_1784	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ANH9381_1785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ANH9381_1785	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ANH9381_1791	COG1840	ABC-type Fe3 transport system, periplasmic component
ANH9381_1795	COG1178	ABC-type Fe3 transport system permease component
ANH9381_1796	COG3842	ATPase activity
ANH9381_1797	COG3101	peptidyl-lysine hydroxylation
ANH9381_1798	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANH9381_1800	COG0788	formyltetrahydrofolate deformylase activity
ANH9381_1801	COG2916	Histone family protein nucleoid-structuring protein H-NS
ANH9381_1802	COG1757	Na H antiporter
ANH9381_1809	COG3161	chorismate lyase activity
ANH9381_1811	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANH9381_1812	COG1758	RNA polymerase activity
ANH9381_1814	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANH9381_1816	COG2867	negative regulation of translational initiation
ANH9381_1818	COG2850	peptidyl-arginine hydroxylation
ANH9381_1821	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANH9381_1822	COG1137	ATPase activity
ANH9381_1823	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ANH9381_1824	COG3117	lipopolysaccharide transmembrane transporter activity
ANH9381_1825	COG1127	ABC transporter
ANH9381_1826	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANH9381_1827	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ANH9381_1828	COG2854	intermembrane phospholipid transfer
ANH9381_1829	COG3113	response to antibiotic
ANH9381_1830	COG5007	Belongs to the BolA IbaG family
ANH9381_1834	COG0463	Glycosyl transferase, family 2
ANH9381_1835	COG3691	Protein conserved in bacteria
ANH9381_1836	COG2067	long-chain fatty acid transport protein
ANH9381_1837	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANH9381_1839	COG0861	Integral membrane protein TerC family
ANH9381_1842	COG2801	Transposase and inactivated derivatives
ANH9381_1844	COG0174	glutamine synthetase
ANH9381_1852	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANH9381_1856	COG0517	IMP dehydrogenase activity
ANH9381_1856	COG1125	glycine betaine transport
ANH9381_1857	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANH9381_1864	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ANH9381_1865	COG2091	lysine biosynthetic process via aminoadipic acid
ANH9381_1866	COG0330	HflC and HflK could
ANH9381_1867	COG0330	HflC and HflK could
ANH9381_1869	COG1555	photosystem II stabilization
ANH9381_1870	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANH9381_1872	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANH9381_1873	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ANH9381_1874	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANH9381_1876	COG0800	Aldolase
ANH9381_1878	COG1028	Short-chain dehydrogenase reductase Sdr
ANH9381_1879	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANH9381_1881	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANH9381_1884	COG2186	Transcriptional regulator
ANH9381_1889	COG0659	secondary active sulfate transmembrane transporter activity
ANH9381_1891	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANH9381_1892	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANH9381_1894	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANH9381_1896	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANH9381_1900	COG3115	cell septum assembly
ANH9381_1902	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANH9381_1904	COG1573	uracil-dna glycosylase
ANH9381_1905	COG0012	GTP binding
ANH9381_1906	COG0193	aminoacyl-tRNA hydrolase activity
ANH9381_1908	COG2801	Transposase and inactivated derivatives
ANH9381_1919	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANH9381_1920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ANH9381_1922	COG0024	Methionine aminopeptidase
ANH9381_1923	COG0316	Belongs to the HesB IscA family
ANH9381_1925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANH9381_1926	COG0672	)-iron permease
ANH9381_1929	COG0577	efflux transmembrane transporter activity
ANH9381_1931	COG1136	(ABC) transporter
ANH9381_1931	COG0577	efflux transmembrane transporter activity
ANH9381_1932	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANH9381_1934	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANH9381_1936	COG3385	transposase activity
ANH9381_1938	COG1643	Atp-dependent helicase
ANH9381_1939	COG2363	Small membrane protein
ANH9381_1947	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ANH9381_1948	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ANH9381_1951	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANH9381_1952	COG1737	Transcriptional regulator
ANH9381_1954	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ANH9381_1955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANH9381_1957	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ANH9381_1958	COG1263	PTS System
ANH9381_1958	COG2190	(PTS) system
ANH9381_1958	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANH9381_1962	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ANH9381_1963	COG3683	transport system, periplasmic component
ANH9381_1964	COG0488	(ABC) transporter
ANH9381_1966	COG0187	DNA topoisomerase II activity
ANH9381_1970	COG0625	glutathione transferase activity
ANH9381_1971	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ANH9381_1973	COG0251	oxidation-reduction process
ANH9381_1976	COG0463	Glycosyl transferase, family 2
ANH9381_1981	COG1560	Kdo2-lipid A biosynthetic process
ANH9381_1982	COG0730	response to heat
ANH9381_1983	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ANH9381_1984	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANH9381_1985	COG3264	Mechanosensitive ion channel
ANH9381_1985	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ANH9381_1986	COG0318	PFAM AMP-dependent synthetase and ligase
ANH9381_1987	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ANH9381_1988	COG0596	Alpha beta hydrolase
ANH9381_1989	COG0716	FMN binding
ANH9381_1990	COG0735	belongs to the Fur family
ANH9381_1991	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANH9381_1992	COG3094	Invasion gene expression up-regulator, SirB
ANH9381_1993	COG0023	Translation Initiation Factor
ANH9381_1995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ANH9381_1996	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ANH9381_1997	COG0776	regulation of translation
ANH9381_1998	COG0539	negative regulation of cytoplasmic translation
ANH9381_2000	COG2990	Protein conserved in bacteria
ANH9381_2001	COG4771	TonB-dependent receptor
ANH9381_2002	COG0612	Peptidase, M16
ANH9381_2003	COG1687	branched-chain amino acid
ANH9381_2004	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ANH9381_2005	COG0583	DNA-binding transcription factor activity
ANH9381_2012	COG2920	part of a sulfur-relay system
ANH9381_2014	COG1121	(ABC) transporter
ANH9381_2015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANH9381_2016	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANH9381_2021	COG3304	Inner membrane component domain
ANH9381_2022	COG1289	transmembrane transporter activity
ANH9381_2025	COG3958	Transketolase
ANH9381_2026	COG3959	Transketolase, thiamine diphosphate binding domain
ANH9381_2034	COG1346	cytolysis
ANH9381_2037	COG1525	nuclease
ANH9381_2038	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANH9381_2039	COG2166	iron-sulfur cluster assembly
ANH9381_2040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANH9381_2040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ANH9381_2041	COG1560	Kdo2-lipid A biosynthetic process
ANH9381_2042	COG3381	protein complex oligomerization
ANH9381_2043	COG2249	NAD(P)H dehydrogenase (quinone) activity
ANH9381_2045	COG0330	HflC and HflK could
ANH9381_2049	COG1858	cytochrome C peroxidase
ANH9381_2050	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ANH9381_2051	COG0318	PFAM AMP-dependent synthetase and ligase
ANH9381_2052	COG3065	identical protein binding
ANH9381_2053	COG1214	PFAM Peptidase M22, glycoprotease
ANH9381_2054	COG1199	ATP-dependent helicase activity
ANH9381_2055	COG0676	glucose-6-phosphate 1-epimerase activity
ANH9381_2056	COG3118	belongs to the thioredoxin family
ANH9381_2057	COG0492	ferredoxin-NADP+ reductase activity
ANH9381_2060	COG1946	Acyl-CoA thioesterase
ANH9381_2062	COG0515	serine threonine protein kinase
ANH9381_2065	COG1940	carbohydrate kinase activity
ANH9381_2066	COG0671	phosphoesterase, PA-phosphatase related
ANH9381_2067	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANH9381_2069	COG1088	dTDP-glucose 4,6-dehydratase activity
ANH9381_2071	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ANH9381_2072	COG0708	Exodeoxyribonuclease III
ANH9381_2079	COG1216	Glycosyl transferase, family 2
ANH9381_2080	COG2246	polysaccharide biosynthetic process
ANH9381_2085	COG0463	Glycosyl transferase, family 2
ANH9381_2092	COG2951	lytic endotransglycosylase activity
ANH9381_2093	COG1216	Glycosyl transferase, family 2
ANH9381_2094	COG1216	Glycosyl transferase, family 2
ANH9381_2096	COG3306	glycosyltransferase involved in LPS biosynthesis
ANH9381_2098	COG5039	Polysaccharide pyruvyl transferase
ANH9381_2099	COG2161	toxin-antitoxin pair type II binding
ANH9381_2100	COG4115	mRNA cleavage
ANH9381_2101	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ANH9381_2103	COG1793	dna ligase
ANH9381_2108	COG3265	gluconokinase activity
ANH9381_2109	COG1609	Transcriptional regulator
ANH9381_2110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ANH9381_2113	COG0437	4 iron, 4 sulfur cluster binding
ANH9381_2114	COG2864	formate dehydrogenase
ANH9381_2115	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ANH9381_2116	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANH9381_2117	COG0651	ATP synthesis coupled electron transport
ANH9381_2118	COG0650	Formate hydrogenlyase subunit 4
ANH9381_2119	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANH9381_2120	COG4237	Hydrogenase 4 membrane
ANH9381_2121	COG0651	ATP synthesis coupled electron transport
ANH9381_2122	COG3261	NADH dehydrogenase
ANH9381_2122	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ANH9381_2123	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANH9381_2124	COG3260	NADH ubiquinone oxidoreductase 20
ANH9381_2126	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ANH9381_2127	COG3383	formate dehydrogenase (NAD+) activity
ANH9381_2128	COG3383	formate dehydrogenase (NAD+) activity
ANH9381_2129	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ANH9381_2132	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANH9381_2133	COG0567	Dehydrogenase, E1 component
ANH9381_2134	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANH9381_2135	COG3108	Peptidase M15
ANH9381_2136	COG2989	Protein conserved in bacteria
ANH9381_2137	COG0793	Belongs to the peptidase S41A family
ANH9381_2139	COG2995	paraquat-inducible protein a
ANH9381_2140	COG3008	intermembrane lipid transfer
ANH9381_2143	COG3842	ATPase activity
ANH9381_2146	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ANH9381_2149	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ANH9381_2151	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANH9381_2154	COG1522	sequence-specific DNA binding
ANH9381_2155	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ANH9381_2156	COG3025	triphosphatase activity
ANH9381_2157	COG1392	Phosphate transport regulator
ANH9381_2158	COG0306	phosphate transporter
ANH9381_2159	COG4991	sh3 domain protein
ANH9381_2160	COG0617	tRNA 3'-terminal CCA addition
ANH9381_2161	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ANH9381_2162	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ANH9381_2166	COG1620	l-lactate permease
ANH9381_2172	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ANH9381_2173	COG0328	RNA-DNA hybrid ribonuclease activity
ANH9381_2174	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANH9381_2178	COG2026	Addiction module toxin, RelE StbE family
ANH9381_2186	COG1862	Preprotein translocase
ANH9381_2187	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANH9381_2188	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANH9381_2191	COG1454	alcohol dehydrogenase
ANH9381_2191	COG1012	belongs to the aldehyde dehydrogenase family
ANH9381_2192	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANH9381_2193	COG1129	ABC transporter
ANH9381_2194	COG1879	ABC-type sugar transport system periplasmic component
ANH9381_2196	COG0673	inositol 2-dehydrogenase activity
ANH9381_2198	COG2271	Major facilitator Superfamily
ANH9381_2200	COG3718	enzyme involved in inositol metabolism
ANH9381_2203	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANH9381_2204	COG3962	Belongs to the TPP enzyme family
ANH9381_2207	COG0673	inositol 2-dehydrogenase activity
ANH9381_2208	COG3722	fumarate hydratase activity
ANH9381_2209	COG0246	Mannitol dehydrogenase
ANH9381_2211	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANH9381_2212	COG2274	protein secretion by the type I secretion system
ANH9381_2213	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ANH9381_2214	COG2994	toxin metabolic process
ANH9381_2216	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANH9381_2221	COG2813	Specifically methylates the guanine in position
ANH9381_2222	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ANH9381_2223	COG0456	acetyltransferase
ANH9381_2224	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity