locus-tag	class	description
D11S_0003	ENOG4108WTW	DNA transposition protein
D11S_0004	ENOG4106YXT	transposase
D11S_0005	ENOG4105R8V	Transcriptional regulator
D11S_0008	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D11S_0009	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D11S_0011	ENOG4105DJ4	phosphatidylserine decarboxylase
D11S_0012	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D11S_0013	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D11S_0014	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D11S_0014	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D11S_0016	ENOG4105DWK	Membrane
D11S_0017	ENOG4107XM3	UPF0442 protein
D11S_0018	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
D11S_0019	ENOG4105C37	(CBS) domain
D11S_0021	ENOG4105RX8	Protein of unknown function (DUF1523)
D11S_0022	ENOG4105F8V	Hydrolase, tatD family
D11S_0023	ENOG4107QRG	dna polymerase iii
D11S_0024	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D11S_0025	ENOG4105HHA	aminodeoxychorismate lyase
D11S_0026	ENOG4108YZA	Nitrogen regulatory protein pii
D11S_0027	ENOG4105MVE	transcriptional regulator
D11S_0028	ENOG4105ZXK	Dehydrogenase
D11S_0029	ENOG4105G63	Type III effector Hrp-dependent
D11S_0030	ENOG4105FB2	class II Aldolase
D11S_0031	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
D11S_0032	ENOG4105C6Z	Gluconate
D11S_0036	ENOG4108K4B	hydrolase
D11S_0037	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D11S_0039	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
D11S_0040	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
D11S_0041	ENOG4108WFC	UPF0438 protein yifE
D11S_0042	ENOG4108Z33	Thiol disulfide Interchange Protein
D11S_0044	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D11S_0046	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
D11S_0047	ENOG4105DE4	1-phosphofructokinase
D11S_0048	ENOG4105DM4	PTS System
D11S_0056	ENOG4105PM1	preprotein translocase subunit SecE
D11S_0057	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D11S_0061	ENOG4108VZM	50s ribosomal protein L10
D11S_0062	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D11S_0063	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D11S_0064	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D11S_0065	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D11S_0066	ENOG41083MP	50s ribosomal protein l29
D11S_0067	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D11S_0068	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D11S_0069	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D11S_0071	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D11S_0073	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D11S_0074	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D11S_0076	ENOG4105CMU	LysR family (Transcriptional regulator
D11S_0077	ENOG4107QP7	CoA-transferase subunit A
D11S_0078	ENOG4107QNJ	CoA-transferase subunit B
D11S_0079	ENOG4105CRW	Short chain fatty acid transporter
D11S_0080	ENOG4105CHU	acetyl-coa acetyltransferase
D11S_0081	ENOG4105EW9	transcriptional regulator AsnC family
D11S_0082	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
D11S_0083	ENOG4105C5B	carbamate kinase
D11S_0084	ENOG4105DBV	ornithine carbamoyltransferase
D11S_0086	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D11S_0088	ENOG4108VVK	transcriptional Regulator, AsnC
D11S_0089	ENOG4108I5U	Uridine phosphorylase
D11S_0091	ENOG4105K89	arsenate reductase
D11S_0094	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
D11S_0095	ENOG4105KJF	protein tyrosine phosphatase
D11S_0096	ENOG4105Z2P	Protein of unknown function (DUF465)
D11S_0097	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D11S_0099	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
D11S_0101	ENOG4105C1A	potassium transporter peripheral membrane
D11S_0102	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D11S_0111	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
D11S_0112	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
D11S_0114	ENOG4105D01	(LipO)protein
D11S_0116	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D11S_0117	ENOG4108MJ5	VirK protein
D11S_0119	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D11S_0124	ENOG41088T4	Helicase IV
D11S_0131	ENOG4107QMH	DNA methylase
D11S_0139	ENOG4105PXI	polysaccharide deacetylase
D11S_0140	ENOG41063SB	peptidase
D11S_0141	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
D11S_0142	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D11S_0143	ENOG4105XWI	UPF0304 protein
D11S_0144	ENOG410903C	(LipO)protein
D11S_0145	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
D11S_0146	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D11S_0152	ENOG4105CIC	tryptophan-specific transport protein
D11S_0153	ENOG4105F0N	pyrophosphate phospho-hydrolase
D11S_0154	ENOG4105ERG	peptidase m48, ste24p
D11S_0155	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D11S_0156	ENOG4105C31	Tryptophanyl-tRNA synthetase
D11S_0157	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D11S_0158	ENOG4106H78	methyltransferase
D11S_0159	ENOG4108EQA	pts system
D11S_0160	ENOG4105ETZ	PTS System
D11S_0161	ENOG4105F3R	pts system mannose fructose sorbose family iid
D11S_0162	ENOG410667J	hydrolase
D11S_0163	ENOG4105D9N	nucleoside
D11S_0167	ENOG4107BJW	polysaccharide deacetylase
D11S_0168	ENOG4105CND	Glycosyl transferase, family 2
D11S_0171	ENOG4105CXY	transporter
D11S_0177	ENOG4105C1J	atp-dependent rna helicase
D11S_0179	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D11S_0181	ENOG4105D3G	Pseudouridine synthase
D11S_0184	ENOG4105W39	Membrane
D11S_0185	ENOG4108UW5	maltose o-acetyltransferase
D11S_0192	ENOG4105C4R	Atp-dependent dna helicase
D11S_0195	ENOG4105C2M	dna polymerase I
D11S_0198	ENOG4105CGH	5'-nucleotidase
D11S_0199	ENOG4106W3N	
D11S_0201	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
D11S_0203	ENOG4105XA0	heptosyltransferase ii
D11S_0204	ENOG4106032	Glutathionylspermidine synthase
D11S_0205	ENOG4105CUW	cytochrome C-TYPE protein
D11S_0206	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
D11S_0207	ENOG4105GXZ	Ferredoxin-type protein NapH
D11S_0208	ENOG4108BGM	Quinol dehydrogenase periplasmic component
D11S_0212	ENOG4105BZU	Histidine kinase
D11S_0213	ENOG4105D4A	Cell wall formation (By similarity)
D11S_0215	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D11S_0221	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D11S_02215	ENOG4105M7P	phage repressor
D11S_02225	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D11S_0224	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D11S_0225	ENOG4105EMY	transcriptional regulator
D11S_0226	ENOG4105DTR	rard protein
D11S_0227	ENOG4105E2X	shikimate dehydrogenase
D11S_02275	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D11S_0228	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D11S_0229	ENOG4108WI1	Dna topoisomerase
D11S_0230	ENOG4105CGY	Dna recombination protein
D11S_0231	ENOG4108TEB	UPF0114 protein
D11S_0232	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D11S_0234	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
D11S_0235	ENOG4105E98	transcriptional regulator DeoR family
D11S_02375	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D11S_0238	ENOG4105CQ0	ABC transporter
D11S_02385	ENOG4105VPB	50S ribosomal protein L30
D11S_0239	ENOG4105D0C	transport protein
D11S_0243	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D11S_02440	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D11S_0245	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D11S_0246	ENOG4105KNE	Phosphatidate cytidylyltransferase
D11S_0247	ENOG4105DZP	Membrane-associated zinc metalloprotease
D11S_0248	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D11S_02480	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D11S_02490	ENOG4105C4Y	ABC transporter
D11S_0250	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D11S_0251	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D11S_0252	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D11S_0253	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D11S_02550	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
D11S_0257	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
D11S_0259	ENOG4108HPI	phosphatidate Cytidylyltransferase
D11S_02590	ENOG4105CAF	HipA N-terminal domain protein
D11S_0260	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D11S_02635	ENOG4105VT2	5-hydroxyisourate hydrolase
D11S_02660	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D11S_0267	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D11S_0268	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D11S_0269	ENOG4105KME	endoribonuclease L-psp
D11S_0270	ENOG4105Y3E	Modulates RecA activity (By similarity)
D11S_0271	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D11S_0272	ENOG4105C5H	ABC transporter
D11S_0273	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D11S_0275	ENOG410689M	(LipO)protein
D11S_0278	ENOG4105IYK	transposase
D11S_02780	ENOG4108BMY	protease
D11S_0280	ENOG4107FB0	transcriptional regulator DeoR family
D11S_0282	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D11S_0283	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D11S_0284	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D11S_02855	ENOG4108RS6	transposase
D11S_0288	ENOG4105CJP	fad dependent oxidoreductase
D11S_02885	ENOG4105EAQ	(twin-arginine translocation) pathway signal
D11S_0289	ENOG4105EAB	amino acid AbC transporter
D11S_0290	ENOG4105E5Q	amino acid AbC transporter
D11S_0291	ENOG4105CDA	abc transporter atp-binding protein
D11S_0293	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
D11S_02935	ENOG4105K63	Thioredoxin
D11S_0294	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
D11S_0295	ENOG4105WWK	YheO domain protein
D11S_0296	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D11S_0297	ENOG4105VRX	Protein slyX homolog
D11S_0298	ENOG4105EHV	domain protein
D11S_0299	ENOG4105C5Q	Transcriptional regulator
D11S_0300	ENOG4105EJ2	Transcriptional regulator
D11S_0301	ENOG4105BZ1	(ABC) transporter
D11S_0302	ENOG4108JJ9	ABC, transporter
D11S_0303	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
D11S_0304	ENOG4107YZP	Rhodanese domain protein
D11S_0305	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D11S_0306	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D11S_0307	ENOG4105D7W	serine acetyltransferase
D11S_0310	ENOG4105CBT	Fructose-1,6-bisphosphatase
D11S_0311	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
D11S_0312	ENOG4105QTB	Flavodoxin
D11S_0314	ENOG4105ECR	NmrA family
D11S_0315	ENOG4105KVH	Transcriptional regulator
D11S_0316	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D11S_0321	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D11S_0323	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D11S_0325	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D11S_0326	ENOG4107RUE	extracellular solute-binding protein family 1
D11S_0334	ENOG4105F3R	pts system mannose fructose sorbose family iid
D11S_0335	ENOG4105ETZ	PTS System
D11S_0336	ENOG4108EQA	pts system
D11S_0337	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
D11S_0338	ENOG4105T16	Transcriptional regulator (AraC family)
D11S_0342	ENOG4105C87	Aminotransferase class I and II
D11S_0343	ENOG4108HWW	ABC transporter
D11S_0344	ENOG4105C2J	ABC transporter
D11S_0345	ENOG4105DFW	ABC transporter
D11S_0346	ENOG4105C93	Xylose Isomerase
D11S_0347	ENOG4105CMG	Carbohydrate kinase
D11S_0351	ENOG4105DQ6	Transposase
D11S_0352	ENOG4105JIM	Phosphatidylserine synthase
D11S_0353	ENOG4105EIB	trna rrna methyltransferase
D11S_0354	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D11S_0355	ENOG41083KI	ribonuclease, T2
D11S_0357	ENOG4105D2N	Aldolase
D11S_0359	ENOG4105PF3	O-Antigen polymerase
D11S_0360	ENOG4108EUD	Lysophospholipase
D11S_0361	ENOG4105DQF	Hydrolase
D11S_0363	ENOG4105C7B	Threonine dehydratase
D11S_0364	ENOG4105C7B	Threonine dehydratase
D11S_0365	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D11S_0366	ENOG4105CAK	Cell division ATP-binding protein ftsE
D11S_0367	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D11S_0368	ENOG4105DJV	ribulose-phosphate 3-epimerase
D11S_0369	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D11S_0370	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D11S_0372	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
D11S_0373	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D11S_0374	ENOG4108UM1	dedA family
D11S_0376	ENOG4108K5P	(LipO)protein
D11S_0378	ENOG4106WTF	Glycosyl transferase, family 2
D11S_0379	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
D11S_0382	ENOG4105DKP	glycosyl transferase, family 9
D11S_0384	ENOG4105E7U	AraC family transcriptional regulator
D11S_0385	ENOG4105BZ1	(ABC) transporter
D11S_0386	ENOG4105E55	glycerol-3-phosphate acyltransferase
D11S_0387	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D11S_0389	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D11S_0392	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D11S_0393	ENOG4105C79	DNA protecting protein DprA
D11S_0394	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
D11S_0395	ENOG4105CXY	transporter
D11S_0397	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D11S_0398	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D11S_0399	ENOG4105DFF	Rod shape-determining protein mreb
D11S_0400	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
D11S_0408	ENOG4107RAQ	aminopeptidase
D11S_0409	ENOG4105E07	UPF0149 protein
D11S_0410	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
D11S_0411	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D11S_0412	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D11S_0413	ENOG4105C34	Pseudouridine synthase
D11S_0414	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D11S_0415	ENOG4105E0M	Sulfatase
D11S_0416	ENOG4108RCM	Nitroreductase
D11S_0417	ENOG4105VZ9	UPF0235 protein
D11S_0418	ENOG4108VIA	integral membrane protein
D11S_0419	ENOG4107QUT	magnesium and cobalt transport protein CorA
D11S_0420	ENOG4108BSC	Methyltransferase
D11S_0422	ENOG4105BZS	acriflavin resistance protein
D11S_0423	ENOG410624X	efflux transporter, rnd family, mfp subunit
D11S_0424	ENOG4105Y7M	Transcriptional regulator, TetR family
D11S_0425	ENOG41063M6	Cell Division Protein
D11S_0426	ENOG4105C25	Primosomal protein n'
D11S_0427	ENOG4108SEH	involved in lipopolysaccharide biosynthesis
D11S_0429	ENOG4105W1T	Glycosyl Transferase
D11S_0432	ENOG4105W1T	Glycosyl Transferase
D11S_0436	ENOG4105W0E	50S ribosomal protein L33
D11S_0440	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D11S_0442	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
D11S_0443	ENOG4105YP7	UPF0270 protein
D11S_0444	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
D11S_0445	ENOG4105DC8	reductase
D11S_0446	ENOG4105D6S	protein involved in catabolism of external DNA
D11S_0447	ENOG4108JQC	penicillin-binding protein 1A
D11S_0452	ENOG4105E4G	Type IV pilus
D11S_0453	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D11S_0454	ENOG4105D49	3-dehydroquinate synthase
D11S_0455	ENOG4105DFE	Dna adenine methylase
D11S_0456	ENOG4108UUM	single-stranded DNA-binding protein
D11S_0457	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D11S_0458	ENOG4105W1Y	Transcriptional regulator
D11S_0461	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D11S_0462	ENOG4105M6F	mutator MutT protein
D11S_0463	ENOG4105DJF	DNA polymerase III, delta' subunit
D11S_0468	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
D11S_0469	ENOG41060A7	DNA polymerase beta domain protein region
D11S_0470	ENOG41062MS	nucleotidyltransferase substrate binding protein
D11S_0471	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D11S_0472	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D11S_0473	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D11S_0474	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D11S_0476	ENOG41075W9	High frequency lysogenization protein HflD homolog
D11S_0477	ENOG4107QTF	adenylosuccinate lyase
D11S_0479	ENOG4105EMU	Dehydrogenase
D11S_0480	ENOG4105VUF	Transcriptional regulator
D11S_0481	ENOG4107QPD	alcohol dehydrogenase
D11S_0482	ENOG4105C4W	S-formylglutathione hydrolase
D11S_0484	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D11S_0485	ENOG4106KVJ	cytochrome C assembly protein
D11S_0486	ENOG4108JU6	CBS domain protein
D11S_0487	ENOG4105M8K	biopolymer transport protein
D11S_0488	ENOG4105M15	transport protein ExbD
D11S_0489	ENOG41067XB	TonB family
D11S_0493	ENOG4107QY8	reductase
D11S_0494	ENOG4105QAX	Iron-sulfur
D11S_0495	ENOG4107KGK	dmso reductase anchor subunit
D11S_0496	ENOG4108NEM	leader-binding protein dmsD
D11S_0497	ENOG4105N1P	Ferredoxin-type protein
D11S_0499	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
D11S_0503	ENOG4105D52	delta-aminolevulinic acid dehydratase
D11S_0504	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D11S_0505	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
D11S_0506	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D11S_0507	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
D11S_0508	ENOG4105VEJ	Heat shock protein
D11S_0509	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
D11S_0510	ENOG4107RK2	ADP-ribose diphosphatase NudE
D11S_0511	ENOG4105E7U	AraC family transcriptional regulator
D11S_0512	ENOG4108KBJ	Inner membrane protein YkgB
D11S_0513	ENOG4105EPD	Oligopeptide transporter, Opt family
D11S_0515	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D11S_0516	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D11S_0517	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D11S_0521	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
D11S_0525	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D11S_0526	ENOG4105C2D	reductase
D11S_0528	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D11S_0539	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D11S_0544	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
D11S_0545	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D11S_0546	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D11S_0547	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D11S_0548	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D11S_0551	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D11S_0552	ENOG4105KQC	Competence protein
D11S_0553	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D11S_0554	ENOG4108X4Q	Hydrolase
D11S_0555	ENOG4105MJ2	Competence protein
D11S_0556	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
D11S_0558	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D11S_0559	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D11S_0560	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D11S_0561	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D11S_0562	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D11S_0563	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D11S_0564	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D11S_0565	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D11S_0567	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D11S_0568	ENOG41067V7	50S ribosomal protein L36
D11S_0571	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D11S_0572	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D11S_0573	ENOG4108ZT0	50S ribosomal protein l17
D11S_0574	ENOG4105E0U	tyrosine-specific transport protein
D11S_0575	ENOG4108VVQ	metallophosphoesterase
D11S_0576	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
D11S_0577	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
D11S_0581	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D11S_0582	ENOG4108RR8	protoporphyrinogen oxidase
D11S_0596	ENOG4105M5K	heptosyltransferase
D11S_0597	ENOG4108IJ0	Aspartate ammonia-lyase
D11S_0599	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D11S_0600	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D11S_0601	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D11S_0604	ENOG4105DQ6	Transposase
D11S_0607	ENOG41080IJ	Diacylglycerol kinase
D11S_0608	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D11S_0609	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D11S_0610	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
D11S_0611	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D11S_0614	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
D11S_0615	ENOG4105DSJ	YicC domain protein
D11S_0616	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D11S_0617	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D11S_0618	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D11S_0619	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
D11S_0620	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_0621	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
D11S_0622	ENOG4107QKW	extracellular solute-binding protein family 1
D11S_0623	ENOG41090ED	Protein with unknown function (DUF469)
D11S_0624	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D11S_0625	ENOG4105CEN	a g-specific adenine glycosylase
D11S_0626	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
D11S_0627	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
D11S_0631	ENOG4105IEY	(LipO)protein
D11S_0632	ENOG4105M85	Bola protein
D11S_0637	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D11S_0638	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D11S_0639	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D11S_0640	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
D11S_0642	ENOG4105CJ2	(LipO)protein
D11S_0644	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D11S_0646	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D11S_0647	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D11S_0648	ENOG4108UJU	UPF0301 protein
D11S_0649	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D11S_0651	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
D11S_0652	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D11S_0653	ENOG4107QKV	phosphomannomutase
D11S_0654	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
D11S_0655	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D11S_0656	ENOG4108M6U	Universal stress protein A
D11S_0657	ENOG4105DXN	mazG family
D11S_0659	ENOG4105E68	Sulfatase
D11S_0660	ENOG4105YDX	UPF0352 protein
D11S_0662	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D11S_0663	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D11S_0664	ENOG4105E0F	Histidine kinase
D11S_0665	ENOG4105D6U	Sodium Glutamate Symporter
D11S_0666	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D11S_0667	ENOG4107S2Z	UPF0761 membrane protein
D11S_0668	ENOG4105K5B	UPF0225 protein
D11S_0670	ENOG4105D7A	ATP-binding protein
D11S_0672	ENOG4105EQ2	LysR family Transcriptional regulator
D11S_0674	ENOG4105CPC	Aldo Keto reductase
D11S_0675	ENOG4105EBR	Carboxylesterase
D11S_0678	ENOG4105EQ2	LysR family Transcriptional regulator
D11S_0681	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D11S_0682	ENOG410804X	Transcriptional regulator
D11S_0683	ENOG4105K70	DNA-binding protein
D11S_0684	ENOG4105R2J	Conserved Protein
D11S_0685	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D11S_0690	ENOG4105C9X	ppx gppa phosphatase
D11S_0691	ENOG4105MA0	exported protein
D11S_0692	ENOG4105CFU	surface antigen
D11S_0693	ENOG4105WH1	Two component transcriptional regulator luxr family
D11S_0694	ENOG4107T0K	Adenylate cyclase
D11S_0695	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D11S_0697	ENOG4105ECF	c-methyltransferase
D11S_0698	ENOG410601J	HemY protein
D11S_0699	ENOG4105EX9	Membrane
D11S_0701	ENOG4108WQI	RNA Polymerase
D11S_0703	ENOG4108RRZ	Transcription elongation factor GreB
D11S_0705	ENOG4108TGR	phosphatase
D11S_0710	ENOG4105BZM	domain protein
D11S_0711	ENOG4105CMG	Carbohydrate kinase
D11S_0712	ENOG4105CNN	ABC, transporter
D11S_0713	ENOG4105C2J	ABC transporter
D11S_0722	ENOG4105CS9	pantothenic acid kinase
D11S_0723	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D11S_0724	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D11S_0725	ENOG4105XQ6	frataxin-like protein
D11S_0727	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D11S_0728	ENOG4105R3P	Inner membrane protein yagU
D11S_0729	ENOG4108R3E	Dna-3-methyladenine glycosylase i
D11S_0730	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D11S_0733	ENOG4105CIN	aminoacyl-histidine dipeptidase
D11S_0734	ENOG4108IXY	short-chain dehydrogenase reductase
D11S_0735	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
D11S_0736	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
D11S_0737	ENOG4105VQK	sigma E regulatory protein, MucB RseB
D11S_0738	ENOG41069PW	sigma-e factor negative regulatory protein
D11S_0739	ENOG4105EMN	RNA polymerase sigma factor
D11S_0740	ENOG4105Y75	tpr repeat protein
D11S_0742	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D11S_0743	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
D11S_0744	ENOG4105EM7	Selenocysteine-specific translation elongation factor
D11S_0748	ENOG4108R99	pseudouridine synthase
D11S_0749	ENOG4105C8J	)-transporter
D11S_0766	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D11S_0770	ENOG4108JA2	transcriptioN-repair coupling factor
D11S_0772	ENOG4105E5Z	arginine transporter ATP-binding subunit
D11S_0773	ENOG4106PMH	Extracellular solute-binding protein family 3
D11S_0774	ENOG4105GBT	ABC transporter
D11S_0775	ENOG4105DMR	ABC, transporter
D11S_0777	ENOG4108V6E	Cell division protein mraZ
D11S_0778	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D11S_0780	ENOG4105CJN	penicillin-binding protein
D11S_0781	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D11S_0782	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
D11S_0783	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D11S_0784	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D11S_0785	ENOG4105CNI	cell division protein FtsW
D11S_0786	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D11S_0787	ENOG4105DFU	Cell wall formation (By similarity)
D11S_0788	ENOG4105CPF	Cell wall formation (By similarity)
D11S_0789	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
D11S_0790	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D11S_0791	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D11S_0795	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D11S_0796	ENOG4105KUZ	arsenate reductase
D11S_0799	ENOG41087AY	ADP-Ribose pyrophosphatase
D11S_0800	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
D11S_0805	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D11S_0808	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
D11S_0809	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
D11S_0810	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
D11S_0811	ENOG4105E33	succinate dehydrogenase
D11S_0812	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D11S_0814	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
D11S_0815	ENOG4105E0A	ABC, transporter
D11S_0816	ENOG4108IHU	transport system permease protein
D11S_0817	ENOG4105DQ5	transport system permease protein
D11S_0818	ENOG4108HUF	Transporter
D11S_0819	ENOG4105DIN	metallophosphoesterase
D11S_0821	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D11S_0822	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D11S_0826	ENOG4105DFP	Integrase
D11S_0829	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
D11S_0830	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
D11S_0831	ENOG4107SC1	transglycosylase
D11S_0832	ENOG4105K9H	YciI-like protein
D11S_0833	ENOG4105NAU	thioesterase Superfamily protein
D11S_0834	ENOG4107835	probably involved in intracellular septation (By similarity)
D11S_0836	ENOG4105EIF	outer membrane protein W
D11S_0838	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D11S_0841	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D11S_0843	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D11S_0844	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D11S_0846	ENOG4105BZU	Histidine kinase
D11S_0847	ENOG4108HWV	)-transporter
D11S_0849	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
D11S_0850	ENOG41060NJ	transcriptional regulator
D11S_0851	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D11S_0852	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D11S_0853	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D11S_0856	ENOG4107QPK	)-transporter
D11S_0857	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
D11S_0858	ENOG4105CHY	citrate lyase, alpha
D11S_0859	ENOG4105CI0	Citrate lyase
D11S_0861	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
D11S_0863	ENOG4108JU5	Magnesium and cobalt efflux protein
D11S_0864	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D11S_0867	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D11S_0868	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D11S_0869	ENOG4105E2D	ec 3.2.1.52
D11S_0871	ENOG4105D1F	ATP-binding protein
D11S_0872	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D11S_0873	ENOG4105WVQ	Fe-S assembly protein IscX
D11S_0874	ENOG4108ZIT	Ferredoxin, 2FE-2S
D11S_0875	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
D11S_0876	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
D11S_0877	ENOG4108Z4V	iron-sulfur cluster assembly
D11S_0878	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
D11S_0880	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
D11S_0881	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
D11S_0882	ENOG4105ECY	inositol monophosphatase
D11S_0884	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_0885	ENOG4107RCV	ABC transporter, permease
D11S_0887	ENOG4105C4Y	ABC transporter
D11S_0891	ENOG4105F27	Major Facilitator
D11S_0892	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D11S_0895	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D11S_0897	ENOG4105CK7	Sodium proline symporter
D11S_0898	ENOG4105C03	ribonuclease
D11S_0899	ENOG4105E9S	glutaredoxin 2
D11S_0900	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D11S_0908	ENOG4106BMH	cytolethal distending toxin
D11S_0909	ENOG4108TMH	cytolethal distending toxin
D11S_0916	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
D11S_0917	ENOG4105C28	cystathionine
D11S_0920	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
D11S_0921	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D11S_0922	ENOG4105CFG	Acts as a chaperone (By similarity)
D11S_0923	ENOG4106J39	exported protein
D11S_0925	ENOG4105NBI	YecM protein
D11S_0926	ENOG4108XTF	Outer Membrane Lipoprotein
D11S_0927	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D11S_0928	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D11S_0929	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D11S_0930	ENOG4107TT5	NLP P60 protein
D11S_0932	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
D11S_0934	ENOG4108BY2	phosphohistidine phosphatase
D11S_0936	ENOG4105EEI	dihydropteroate synthase
D11S_0937	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D11S_0941	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D11S_0942	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
D11S_0950	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
D11S_0951	ENOG4108EU3	peptide transport system, permease
D11S_0953	ENOG4108EVY	peptide transport periplasmic protein
D11S_0954	ENOG4105CM6	amino acid regulated cytosolic protein
D11S_0955	ENOG4106K28	UPF0283 membrane protein
D11S_0956	ENOG4108JU8	Transcriptional regulator
D11S_0959	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D11S_0961	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D11S_0962	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D11S_0963	ENOG4105K8N	protein family UPF0079, ATPase
D11S_0966	ENOG410838F	Glycosyl transferase family 2
D11S_0967	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
D11S_0969	ENOG4108I6E	Sulfatase
D11S_0973	ENOG4105KZ7	phosphocarrier protein hpr
D11S_0974	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
D11S_0975	ENOG4105C5Y	PTS System
D11S_0976	ENOG4105DGW	oligopeptidase A
D11S_0977	ENOG4105WD1	Membrane
D11S_0978	ENOG4107TSG	Extracellular solute-binding protein, family 5
D11S_0980	ENOG4105CRQ	synthase (Component I)
D11S_0981	ENOG4105DDQ	anthranilate synthase
D11S_0982	ENOG4105C5I	Dehydrogenase
D11S_0983	ENOG4105D60	lipoprotein releasing system transmembrane protein
D11S_0984	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D11S_0985	ENOG4105D60	lipoprotein releasing system transmembrane protein
D11S_0986	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D11S_0988	ENOG4105CDU	Replicative dna helicase
D11S_0989	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D11S_0990	ENOG4107QP8	phosphohexose isomerase
D11S_0991	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D11S_0993	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D11S_0994	ENOG4108ZAI	phosphatidylglycerophosphatase a
D11S_0995	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
D11S_0998	ENOG4105XPH	Ferredoxin
D11S_1000	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D11S_1001	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D11S_1004	ENOG4105C4Y	ABC transporter
D11S_1005	ENOG4107RCV	ABC transporter, permease
D11S_1006	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_1008	ENOG4107T9C	Alpha amylase catalytic region
D11S_1009	ENOG4105EG2	ABC transporter, permease
D11S_1010	ENOG4105D56	permease protein
D11S_1012	ENOG4107FKK	extracellular solute-binding protein family 1
D11S_1013	ENOG4108IJ9	(ABC) transporter
D11S_1014	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
D11S_1015	ENOG4107W52	maltose operon periplasmic protein
D11S_1017	ENOG4105D06	uba thif-type nad fad binding protein
D11S_1018	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D11S_1019	ENOG4105EUJ	GTP cyclohydrolase i
D11S_1020	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
D11S_1021	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D11S_1022	ENOG4105HBR	Rna-binding protein
D11S_1023	ENOG4105VUH	addiction module killer protein
D11S_1024	ENOG4105YES	addiction module antidote protein
D11S_1025	ENOG4108R6K	riboflavin synthase, subunit alpha
D11S_1026	ENOG4107QI1	Mate efflux family protein
D11S_1027	ENOG4108Z66	YbaK ebsC protein
D11S_1028	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D11S_1029	ENOG4105TWJ	Domain of unknown function (DUF1919)
D11S_1040	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D11S_1042	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D11S_1043	ENOG4105DN3	alpha-2-macroglobulin domain protein
D11S_1044	ENOG4105HMI	Membrane
D11S_1045	ENOG4108JQB	penicillin-binding protein 1C
D11S_1050	ENOG4105DW5	Transcriptional regulator
D11S_1051	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
D11S_1052	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
D11S_1053	ENOG4105E0U	tyrosine-specific transport protein
D11S_1055	ENOG4105CNT	hydrolase family 2
D11S_1056	ENOG41090BQ	Glutaredoxin
D11S_1057	ENOG4108DBC	nitroreductase
D11S_1059	ENOG4105D0Y	UPF0227 protein
D11S_1060	ENOG4105RHG	
D11S_1061	ENOG4105C9Q	fumarate hydratase class II
D11S_1062	ENOG4105MYG	DNA polymerase iii, chi subunit
D11S_1071	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
D11S_1074	ENOG4108RMU	ferritin dps family protein
D11S_1076	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D11S_1077	ENOG4107QNR	UPF0135 protein
D11S_1078	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D11S_1079	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
D11S_1080	ENOG4105CRK	lysyL-tRNA synthetase
D11S_1083	ENOG4105T95	Thiol disulfide interChange protein
D11S_1084	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D11S_1086	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D11S_1087	ENOG4105UZ0	ABC-type Co2 transport system, periplasmic component
D11S_1088	ENOG4108A51	
D11S_1089	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
D11S_1091	ENOG4108JJB	ABC transporter
D11S_1093	ENOG4105CQS	hydrogenase expression formation protein HypD
D11S_1094	ENOG4105C45	hydrogenase expression formation protein (HypE)
D11S_1096	ENOG4105F9E	Shikimate 5-dehydrogenase
D11S_1097	ENOG4105SYT	Methylenetetrahydrofolate reductase
D11S_1098	ENOG4108K5H	permease YjgP YjgQ family protein
D11S_1099	ENOG4108M8S	permease YjgP YjgQ family protein
D11S_1100	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D11S_1101	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D11S_1102	ENOG4105E0C	molybdate abc transporter
D11S_1103	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D11S_1104	ENOG4105F4R	Transcriptional regulator mode
D11S_1105	ENOG4105C8P	)-transporter
D11S_1106	ENOG4105DK2	UPF0207 protein
D11S_1107	ENOG4105C0H	protease
D11S_1108	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D11S_1109	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D11S_1110	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
D11S_1111	ENOG4105ETT	transcriptional Regulator, LysR family
D11S_1112	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D11S_1114	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D11S_1115	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
D11S_1116	ENOG4105ECP	epimerase
D11S_1117	ENOG4105DGN	Electron transport complex
D11S_1118	ENOG4108R3D	Electron transport complex
D11S_1119	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
D11S_1122	ENOG4105DZB	Electron transport complex
D11S_1123	ENOG4105CSM	endonuclease III
D11S_1124	ENOG4105C8J	)-transporter
D11S_1125	ENOG4105FAV	ABC, transporter
D11S_1126	ENOG4105FDK	ABC transporter
D11S_1127	ENOG4105DR5	peptidase
D11S_1128	ENOG4108IPW	abc transporter atp-binding protein
D11S_1129	ENOG4105CM4	permease protein
D11S_1130	ENOG4105DHS	permease protein
D11S_1132	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
D11S_1135	ENOG4105H4F	exported protein
D11S_1136	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D11S_1137	ENOG4105DHQ	Histidine kinase
D11S_1138	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D11S_1139	ENOG4106CC8	Bacterial inner membrane protein
D11S_1140	ENOG4105CDH	Citrulline--aspartate ligase
D11S_1141	ENOG4108535	NAD dependent epimerase/dehydratase family
D11S_1143	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D11S_1144	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
D11S_1146	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D11S_1150	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
D11S_1152	ENOG4105DWF	phosphomethylpyrimidine kinase
D11S_1153	ENOG4105DP9	ABC transporter
D11S_1154	ENOG4106SMU	thiamine transporter membrane protein
D11S_1155	ENOG4107T0D	ABC, transporter
D11S_1157	ENOG4105C0H	protease
D11S_1159	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
D11S_1160	ENOG4105DDY	UPF0142 protein ycaO
D11S_1161	ENOG4105EIP	mannose-6-phosphate isomerase
D11S_1162	ENOG4105KWI	UPF0339 protein
D11S_1165	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D11S_1167	ENOG4105E2R	ROK family
D11S_1172	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D11S_1173	ENOG4105EYM	Major Facilitator superfamily
D11S_1174	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
D11S_1175	ENOG4105CMR	udp-glucose 4-epimerase
D11S_1176	ENOG4105KAF	membrAne
D11S_1179	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D11S_1180	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
D11S_1181	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D11S_1185	ENOG410682P	Hypothetical protein (DUF2513)
D11S_1187	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
D11S_1190	ENOG4105WXW	Antirepressor
D11S_1197	ENOG4105CEE	C4-dicarboxylate transporter
D11S_1199	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D11S_1200	ENOG4105CHV	Transcription elongation factor NusA
D11S_1201	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D11S_1202	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D11S_1206	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D11S_1208	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D11S_1209	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D11S_1214	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_1218	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D11S_1220	ENOG41085JB	UPF0434 protein
D11S_1221	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D11S_1222	ENOG4105BZ1	(ABC) transporter
D11S_1223	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
D11S_1224	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
D11S_1227	ENOG4108DNC	Involved in acetate metabolism (By similarity)
D11S_1228	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D11S_1229	ENOG4105PQ6	UPF0208 membrane protein
D11S_1230	ENOG4105E96	Colicin v production protein
D11S_1232	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
D11S_1233	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
D11S_1234	ENOG41061ZR	Transcriptional regulator
D11S_1236	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
D11S_1237	ENOG4107QSN	dihydrolipoamide acetyltransferase
D11S_1238	ENOG4107QN2	dihydrolipoyl dehydrogenase
D11S_1240	ENOG41069NU	Nitroreductase
D11S_1241	ENOG4105D07	Signal peptide peptidase, SppA
D11S_1242	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
D11S_1243	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D11S_1244	ENOG4105FE9	pseudouridine synthase
D11S_1245	ENOG4107R11	Transcriptional regulator
D11S_1246	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D11S_1247	ENOG4105XW2	UPF0263 protein
D11S_1249	ENOG4105ETE	Transcriptional regulator (LacI family
D11S_1250	ENOG4105DWV	Homoserine O-trans-acetylase
D11S_1251	ENOG4107GZ4	SanA protein
D11S_1252	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
D11S_1255	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D11S_1256	ENOG4107QIV	Cytochrome c biogenesis protein
D11S_1257	ENOG4105E0X	reductase
D11S_1258	ENOG41077A9	carbonic anhydrase
D11S_1259	ENOG4105W4M	Transport-associated protein
D11S_1260	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D11S_1261	ENOG41082RQ	UPF0102 protein
D11S_1262	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
D11S_1263	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D11S_1265	ENOG4105CEP	NADH dehydrogenase
D11S_1267	ENOG4105ERU	peptidase
D11S_1269	ENOG4105FGM	Fructosamine kinase
D11S_1270	ENOG4105C22	threonyL-tRNA synthetase
D11S_1276	ENOG4105DP0	ferredoxin-NADP reductase
D11S_1277	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D11S_1279	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D11S_1285	ENOG4105E98	transcriptional regulator DeoR family
D11S_1286	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D11S_1287	ENOG4105CTB	Polyprenyl synthetase
D11S_1288	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D11S_1289	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D11S_1290	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D11S_1291	ENOG4108TGR	phosphatase
D11S_1292	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
D11S_1293	ENOG4105DWU	Membrane
D11S_1297	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
D11S_1303	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
D11S_1305	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
D11S_1307	ENOG4108ZZ3	UPF0260 protein
D11S_1309	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D11S_1310	ENOG4108ESZ	Glycogen debranching enzyme
D11S_1312	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D11S_1313	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
D11S_1315	ENOG4108VD1	dedA family
D11S_1316	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D11S_1318	ENOG41061WM	D-Alanyl-D-Alanine
D11S_1319	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
D11S_1320	ENOG4105CEY	Amp-dependent synthetase and ligase
D11S_1322	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
D11S_1323	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
D11S_1324	ENOG4108TZV	Membrane
D11S_1325	ENOG4105CJB	Exodeoxyribonuclease I
D11S_1330	ENOG41090A1	ferritin
D11S_1331	ENOG41090A1	ferritin
D11S_1333	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D11S_1334	ENOG4105Q9Y	Universal stress protein
D11S_1336	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D11S_1338	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D11S_1339	ENOG4105CD8	aminopeptidase N
D11S_1340	ENOG4105CGF	Aromatic amino acid aminotransferase
D11S_1343	ENOG4105D0S	secretion protein (HlyD
D11S_1346	ENOG4105CMI	transporter
D11S_1348	ENOG4105EHG	Permease protein
D11S_1349	ENOG4105E0A	ABC, transporter
D11S_1350	ENOG4105S10	periplasmic binding protein
D11S_1351	ENOG4105X1Q	TOBE domain protein
D11S_1354	ENOG4107RNH	Outer membrane receptor FepA
D11S_1355	ENOG4105E0A	ABC, transporter
D11S_1356	ENOG4105EHG	Permease protein
D11S_1357	ENOG4105S10	periplasmic binding protein
D11S_1363	ENOG4108QBX	(LipO)protein
D11S_1364	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D11S_1365	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D11S_1366	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D11S_1367	ENOG4105D0M	Protease HtpX homolog
D11S_1368	ENOG4105C2X	Arabinose 5-phosphate isomerase
D11S_1369	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
D11S_1370	ENOG4105CRQ	synthase (Component I)
D11S_1372	ENOG4108V5Q	transglutaminase-like protein
D11S_1374	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D11S_1380	ENOG4107QSA	Oxaloacetate decarboxylase
D11S_1381	ENOG4105D9Q	decarboxylase (Beta subunit)
D11S_1383	ENOG4108MVK	Receptor
D11S_1385	ENOG4105EMU	Dehydrogenase
D11S_1386	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D11S_1388	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D11S_1390	ENOG4105CA9	Pyruvate kinase
D11S_1392	ENOG41061GT	Aldolase
D11S_1393	ENOG4105D4B	ABC, transporter
D11S_1397	ENOG4105DKT	Transcriptional regulator
D11S_1398	ENOG4107RYS	Autoinducer-2 (AI-2) kinase
D11S_1399	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D11S_1400	ENOG4105DAG	ROK family
D11S_1401	ENOG4105C5S	asparaginyl-tRNA synthetase
D11S_1402	ENOG4105KB2	stringent starvation protein b
D11S_1403	ENOG4107MKT	Stringent starvation protein a
D11S_1404	ENOG4108ZAF	Molybdopterin
D11S_1405	ENOG4105M00	molybdopterin converting factor, subunit 1
D11S_1407	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D11S_1408	ENOG4105CHW	UPF0052 protein
D11S_1410	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
D11S_1411	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
D11S_1412	ENOG4105CUW	cytochrome C-TYPE protein
D11S_1413	ENOG4107QY8	reductase
D11S_1414	ENOG4105UNS	Pfam:DUF419
D11S_1415	ENOG4107QPK	)-transporter
D11S_1418	ENOG4105K4U	addiction module toxin, RelE StbE family
D11S_1419	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D11S_1424	ENOG4107QYX	exodeoxyribonuclease v alpha
D11S_1425	ENOG4107QKA	exodeoxyribonuclease V beta
D11S_1426	ENOG41090EX	DsrE family
D11S_1428	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
D11S_1429	ENOG4105DAN	ATP-dependent protease
D11S_1430	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
D11S_1431	ENOG4105VEQ	Cold shock protein
D11S_1432	ENOG4105X5C	UPF0181 protein
D11S_1433	ENOG4105DR9	pseudouridine synthase
D11S_1434	ENOG4105WP7	tRNA pseudouridine synthase C
D11S_1435	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
D11S_1436	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
D11S_1437	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
D11S_1439	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
D11S_1441	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_1443	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_1445	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D11S_1446	ENOG4105CIY	formyltetrahydrofolate deformylase
D11S_1447	ENOG4108SAU	DNA-binding protein H-ns
D11S_1448	ENOG4107S6Z	Na H antiporter
D11S_1455	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D11S_1456	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
D11S_1457	ENOG4105CB5	ATP-dependent DNA helicase recG
D11S_1458	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D11S_1459	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
D11S_1460	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D11S_1462	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D11S_1464	ENOG4108Z1B	Cyclase dehydrase
D11S_1465	ENOG4105VDB	UPF0125 protein
D11S_1466	ENOG4105EZE	Cupin 4 family protein
D11S_1468	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D11S_1469	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D11S_1470	ENOG4108IUZ	ABC transporter
D11S_1471	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
D11S_1472	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
D11S_1473	ENOG4105DHJ	ABC, transporter
D11S_1474	ENOG4105CY3	ABC transporter, permease
D11S_1475	ENOG4107PE3	Mammalian cell entry related domain protein
D11S_1476	ENOG4105E3I	toluene tolerance
D11S_1478	ENOG4105VFK	BolA family
D11S_1479	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D11S_1480	ENOG4105KZW	UPF0381 protein
D11S_1482	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D11S_1484	ENOG4105EE5	Membrane protein terC
D11S_1485	ENOG4105C5F	glutamine synthetase
D11S_1486	ENOG4105CI3	gtp-binding protein typa
D11S_1489	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D11S_1490	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D11S_1491	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D11S_1493	ENOG4108IJ8	ABC transporter
D11S_1494	ENOG4105DFA	alanine racemase domain protein
D11S_1497	ENOG4105CFH	Aspartokinase
D11S_1500	ENOG4105D98	threonine synthase
D11S_1502	ENOG4107QJR	hflk protein
D11S_1503	ENOG4105EPW	hflc protein
D11S_1505	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
D11S_1506	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D11S_1507	ENOG4105K8R	UPF0145 protein
D11S_1508	ENOG4105CSA	Coproporphyrinogen iii oxidase
D11S_1509	ENOG4105E66	phosphoriboisomerase A
D11S_1510	ENOG4108JQ1	Dehydrogenase
D11S_1512	ENOG4105S10	periplasmic binding protein
D11S_1513	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D11S_1515	ENOG4107YCY	Transcriptional regulator
D11S_1520	ENOG4105CHH	sulfate transporter
D11S_1522	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D11S_1523	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D11S_1524	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D11S_1525	ENOG4105VCC	30S ribosomal protein S21
D11S_1527	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D11S_1529	ENOG4107104	thymidine kinase
D11S_1531	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
D11S_1532	ENOG4105EXN	Sulfate transport protein CysZ
D11S_1533	ENOG4105C6T	cysteine synthase
D11S_1536	ENOG4108RG0	uracil-dna glycosylase
D11S_1537	ENOG4105C3G	gtp-binding protein
D11S_1538	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D11S_1550	ENOG4105ESV	Glycosyl transferase, family 4
D11S_1551	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D11S_1552	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D11S_1553	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D11S_1554	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D11S_1556	ENOG4105BZ4	penicillin-binding protein
D11S_1557	ENOG4107SJW	iron permease, FTR1
D11S_1560	ENOG4107RBB	ABC transporter, permease
D11S_1562	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D11S_1563	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D11S_1565	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D11S_1569	ENOG4105CQ7	ATP-dependent helicase
D11S_1570	ENOG4105M08	Membrane
D11S_1571	ENOG4108VMM	UPF0756 membrane protein
D11S_1572	ENOG4105M2J	Glutaredoxin
D11S_1574	ENOG4105CQB	FAD linked oxidase domain protein
D11S_1575	ENOG4105KA0	thioesterase Superfamily protein
D11S_1577	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D11S_1578	ENOG4105CE4	GlcNAc 6-P deacetylase
D11S_1579	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D11S_1580	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D11S_1581	ENOG4105QEK	Transcriptional regulator
D11S_1583	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
D11S_1584	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
D11S_1585	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D11S_1586	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
D11S_1587	ENOG4105CI1	PTS System
D11S_1591	ENOG4105D7X	high-affinity nickel-transporter
D11S_1592	ENOG41065CD	Exported protein
D11S_1594	ENOG4105C5H	ABC transporter
D11S_1596	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D11S_1598	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D11S_1599	ENOG4108K3A	Glutathione S-transferase
D11S_1601	ENOG4108VTV	Inherit from NOG: Membrane
D11S_1602	ENOG4105M4H	endoribonuclease L-psp
D11S_1606	ENOG4107NA1	Endonuclease Exonuclease phosphatase
D11S_1610	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
D11S_1611	ENOG4105EJ9	Membrane
D11S_1612	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
D11S_1613	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D11S_1614	ENOG4105EGS	Mechanosensitive ion channel
D11S_1615	ENOG4105CEY	Amp-dependent synthetase and ligase
D11S_1616	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
D11S_1617	ENOG4105EV9	Alpha Beta Hydrolase
D11S_1618	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
D11S_1619	ENOG41090R7	Ferric uptake
D11S_1620	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D11S_1622	ENOG4108ZJT	translation initiation factor, Sui1
D11S_1624	ENOG4105CFV	Tetratricopeptide repeat protein
D11S_1625	ENOG4105Q4A	inner membrane protein yciS
D11S_1626	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D11S_1627	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D11S_1628	ENOG4105CAT	Cytidine monophosphate kinase
D11S_1629	ENOG4108MJ5	VirK protein
D11S_1630	ENOG4105PE1	Receptor
D11S_1631	ENOG4107RAN	Peptidase, M16
D11S_1632	ENOG4105KMT	branched-chain amino acid
D11S_1633	ENOG4108UMN	azlc family
D11S_1635	ENOG4105DZ2	Transcriptional regulator
D11S_1636	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D11S_1639	ENOG4108MN8	Membrane
D11S_1640	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D11S_1642	ENOG4105DIK	(ABC) transporter
D11S_1643	ENOG4105CC5	ABC transporter
D11S_1644	ENOG4105CC5	ABC transporter
D11S_1645	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
D11S_1646	ENOG41068P6	UPF0319 protein
D11S_1647	ENOG4108Z5K	methylglyoxal synthase
D11S_1648	ENOG410901E	Membrane
D11S_1649	ENOG4105EM2	membrane
D11S_1652	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
D11S_1653	ENOG4108IUS	Transketolase
D11S_1659	ENOG4105C5H	ABC transporter
D11S_1660	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
D11S_1661	ENOG41067MG	lrgb family
D11S_1662	ENOG4105VAW	lrga family
D11S_1664	ENOG4105KK6	nuclease
D11S_1665	ENOG4105C9B	Cysteine desulfurase
D11S_1666	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D11S_1667	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D11S_1668	ENOG4105D1S	lipid A biosynthesis
D11S_1669	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
D11S_1670	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
D11S_1672	ENOG4107QX8	SPFH domain, Band 7 family protein
D11S_1676	ENOG4105CA0	peroxidase
D11S_1677	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
D11S_1678	ENOG4105CEY	Amp-dependent synthetase and ligase
D11S_1679	ENOG4105R8X	Outer membrane lipoprotein Slp
D11S_1680	ENOG41072GX	Peptidase M22 Glycoprotease
D11S_1681	ENOG4105DVT	helicase
D11S_1682	ENOG4105DSB	aldose 1-epimerase
D11S_1683	ENOG4107QR8	Thioredoxin
D11S_1684	ENOG4105C3M	thioredoxin reductase
D11S_1685	ENOG4108JJ9	ABC, transporter
D11S_1686	ENOG4108JJ8	(ABC) transporter
D11S_1688	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
D11S_1690	ENOG4105F3T	(LipO)protein
D11S_1691	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
D11S_1692	ENOG4105EYK	Phosphatidylglycerophosphatase B
D11S_1693	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
D11S_1697	ENOG4105GXY	Family of unknown function (DUF695) 
D11S_1698	ENOG4105CGK	Exodeoxyribonuclease III
D11S_1699	ENOG4105D3Q	Sugar transferase
D11S_1700	ENOG4108KBE	Glycosyl transferase, family 2
D11S_1701	ENOG4108RT7	Glycosyl transferase, family 2
D11S_1707	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D11S_1709	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D11S_1710	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D11S_1711	ENOG4105CVE	Lytic murein transglycosylase
D11S_1712	ENOG4108RYC	glycosyltransferase
D11S_1713	ENOG4108RJ9	Glycosyl transferase, family 2
D11S_1715	ENOG41068D6	Glycosyltransferase
D11S_1717	ENOG4108ZPC	Polysaccharide pyruvyl transferase
D11S_1719	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D11S_1720	ENOG41080C8	DUF218 domain
D11S_1723	ENOG4105C4R	Atp-dependent dna helicase
D11S_1724	ENOG4105C6Z	Gluconate
D11S_1725	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
D11S_1727	ENOG4105DIQ	Transcriptional regulator
D11S_1728	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
D11S_1732	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D11S_1733	ENOG4108MG3	formate dehydrogenase
D11S_1735	ENOG4105C8H	hydrogenase maturation protein Hypf
D11S_1736	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
D11S_1737	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D11S_1738	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D11S_1739	ENOG4107TDF	Formate hydrogenlyase subunit 4
D11S_1740	ENOG4105D65	subunit l
D11S_1741	ENOG4107WQX	hydrogenase 4 membrane subunit
D11S_1742	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D11S_1743	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D11S_1745	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
D11S_1746	ENOG4105I6X	formate hydrogenlyase maturation
D11S_1747	ENOG4108MG9	hydrogenase 3 maturation protease
D11S_1748	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D11S_1749	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D11S_1750	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D11S_1751	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D11S_1753	ENOG4105C7S	Dehydrogenase
D11S_1754	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D11S_1756	ENOG4105C5X	domain protein
D11S_1758	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D11S_1759	ENOG4105CN1	protease
D11S_1760	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
D11S_1761	ENOG4105H2K	paraquat-inducible protein a
D11S_1762	ENOG4105DY2	Paraquat-inducible protein b
D11S_1763	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D11S_1764	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D11S_1765	ENOG4105F38	ABC transporter, permease
D11S_1766	ENOG4105D38	putrescine abc transporter
D11S_1767	ENOG4107RUE	extracellular solute-binding protein family 1
D11S_1768	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
D11S_1771	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
D11S_1772	ENOG4105D1H	recombination factor protein RarA
D11S_1773	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
D11S_1774	ENOG4105CNU	cell division protein FtsK
D11S_1775	ENOG4105EW9	transcriptional regulator AsnC family
D11S_1776	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D11S_1777	ENOG4105I7R	Adenylate cyclase
D11S_1778	ENOG4107IX6	phosphate transport regulator
D11S_1779	ENOG4105CJ3	phosphate transporter
D11S_1781	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D11S_1782	ENOG4108AD6	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
D11S_1783	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D11S_1784	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D11S_1787	ENOG4105DAA	L-lactate
D11S_1789	ENOG41090HJ	UPF0265 protein
D11S_1791	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D11S_1792	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D11S_1793	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D11S_1795	ENOG4107RZZ	dna polymerase iii epsilon subunit
D11S_1799	ENOG4105K4U	addiction module toxin, RelE StbE family
D11S_1802	ENOG4105CFP	Peptidase U32
D11S_1803	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D11S_1804	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D11S_1806	ENOG4105VIE	preprotein translocase, subunit YajC
D11S_1807	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D11S_1808	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D11S_1809	ENOG4107ENK	receptor
D11S_1811	ENOG4108EKI	Dehydrogenase
D11S_1812	ENOG4105CNN	ABC, transporter
D11S_1813	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
D11S_1814	ENOG4105E61	Mannitol repressor protein
D11S_1815	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
D11S_1816	ENOG4105CTS	PTS system mannitol-specific
D11S_1817	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
D11S_1818	ENOG4108JJA	ABC, transporter
D11S_1819	ENOG4105DDI	hemolysin-type calcium-binding region
D11S_1821	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D11S_1824	ENOG4105C5Y	PTS System
D11S_1825	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D11S_1826	ENOG4108WPU	DNA polymerase III subunit psi
D11S_1827	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
D11S_1828	ENOG4105DSY	exodeoxyribonuclease V, gamma
D11S_1836	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D11S_1837	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D11S_1840	ENOG4105E02	MotA TolQ exbB proton channel
D11S_1841	ENOG4107YD3	Thioesterase
D11S_1843	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D11S_1844	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D11S_1850	ENOG4105CDY	transcriptional regulatory protein
D11S_1851	ENOG4108TIT	dATP pyrophosphohydrolase
D11S_1852	ENOG4105K3M	)-transporter
D11S_1854	ENOG4105C9M	aspartyl-trna synthetase
D11S_1855	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
D11S_1863	ENOG4105CXY	transporter
D11S_1864	ENOG4107ENK	receptor
D11S_1865	ENOG4108UYE	Lactoylglutathione lyase
D11S_1866	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
D11S_1867	ENOG4105D3Y	Na H antiporter
D11S_1869	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D11S_1872	ENOG4105WPN	DNA integration recombination invertion protein
D11S_1873	ENOG4105EAH	synthase
D11S_1876	ENOG4105QYV	Membrane
D11S_1877	ENOG4105QYV	Membrane
D11S_1878	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D11S_1884	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D11S_1885	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D11S_1886	ENOG4105C3U	ABC transporter
D11S_1887	ENOG4108JQ7	(ABC) transporter
D11S_1888	ENOG41065U4	response regulator
D11S_1889	ENOG4105NRA	50s ribosomal protein l31 type b
D11S_1890	ENOG4108URH	decarboxylase
D11S_1893	ENOG4105MGM	doxx family
D11S_1895	ENOG4105C03	ribonuclease
D11S_1897	ENOG4105EI2	Pseudouridine synthase
D11S_1899	ENOG4105C5I	Dehydrogenase
D11S_1900	ENOG4105C28	cystathionine
D11S_1908	ENOG4105EN6	Membrane
D11S_1911	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D11S_1912	ENOG4105DFU	Cell wall formation (By similarity)
D11S_1914	ENOG4105CA3	membrane-bound lytic murein transglycosylase
D11S_1915	ENOG4105CUZ	uba thif-type nad fad binding protein
D11S_1916	ENOG4105NXV	High-affinity zinc uptake system protein
D11S_1917	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
D11S_1918	ENOG4108VPT	UPF0234 protein
D11S_1919	ENOG4105EAC	phosphoserine phosphatase
D11S_1920	ENOG41062Z9	Membrane
D11S_1923	ENOG4105CJR	Integral membrane protein (MviN
D11S_1924	ENOG4105DTN	riboflavin biosynthesis protein ribF
D11S_1927	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D11S_1929	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D11S_1930	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D11S_1931	ENOG4105D8G	Major Facilitator superfamily
D11S_1932	ENOG4105II7	pyrroline-5-carboxylate reductase
D11S_1933	ENOG4105II7	pyrroline-5-carboxylate reductase
D11S_1934	ENOG4105DH7	May be involved in recombination (By similarity)
D11S_1936	ENOG4108UBT	opacity-associated protein
D11S_1937	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D11S_1940	ENOG4105C0F	tryptophanase EC 4.1.99.1
D11S_1941	ENOG4105E0U	tyrosine-specific transport protein
D11S_1942	ENOG4105WWK	YheO domain protein
D11S_1944	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D11S_1945	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
D11S_1946	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
D11S_1948	ENOG4105F1A	Pyruvate formate-lyase
D11S_1949	ENOG4105C6N	Formate acetyltransferase
D11S_1950	ENOG4105TMB	Formate nitrite transporter
D11S_1951	ENOG4105K59	histidine triad (HIT) protein
D11S_1953	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D11S_1956	ENOG4105CTQ	phosphohexokinase
D11S_1959	ENOG4105D1Q	UPF0246 protein
D11S_1960	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D11S_1961	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
D11S_1962	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D11S_1963	ENOG4105C3F	Signal peptidase i
D11S_1966	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D11S_1967	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D11S_1969	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D11S_1970	ENOG4105VG0	50S ribosomal protein l34
D11S_1972	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D11S_1973	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D11S_1974	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D11S_1975	ENOG4105DVA	methyltransferase
D11S_1976	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D11S_1980	ENOG4105C6K	Malic enzyme
D11S_1981	ENOG4105CBX	hi0933 family
D11S_1982	ENOG4108DMF	Cytochrome C biogenesis protein
D11S_1983	ENOG4107QX9	Thiol disulfide interChange protein
D11S_1984	ENOG4105DA4	cytochrome c-type biogenesis protein
D11S_1986	ENOG4105DVI	reductase, NrfD
D11S_1987	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D11S_1988	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
D11S_1992	ENOG4108M1T	Cytochrome c-type biogenesis protein
D11S_1993	ENOG4108M1T	Cytochrome c-type biogenesis protein
D11S_1994	ENOG4107QX9	Thiol disulfide interChange protein
D11S_1995	ENOG4105DA4	cytochrome c-type biogenesis protein
D11S_1996	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D11S_1997	ENOG4105X3C	heme exporter protein
D11S_1998	ENOG41060IM	Heme exporter protein
D11S_1999	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D11S_2000	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D11S_2003	ENOG4105I08	Pseudouridine synthase
D11S_2005	ENOG4105C6K	Malic enzyme
D11S_2006	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D11S_2008	ENOG4105CGZ	zinc metallopeptidase
D11S_2009	ENOG4108WZM	domain protein
D11S_2010	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D11S_2011	ENOG4107ZVW	dihydroneopterin aldolase
D11S_2012	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D11S_2014	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
D11S_2015	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D11S_2016	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
D11S_2017	ENOG4105CHM	Aminotransferase
D11S_2018	ENOG4105E4F	Isochorismate synthase
D11S_2019	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
D11S_2020	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
D11S_2021	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D11S_2023	ENOG4105GPY	SprT protein
D11S_2024	ENOG4105C44	Serine transporter
D11S_2025	ENOG4105EJQ	L-serine dehydratase
D11S_2026	ENOG4105HDK	L-asparaginase
D11S_2028	ENOG41090FY	type IV pilus biogenesis stability protein PilW
D11S_2029	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
D11S_2030	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D11S_2031	ENOG4105CUT	histidyl-tRNA synthetase
D11S_2032	ENOG4105N21	Membrane
D11S_2034	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
D11S_2036	ENOG4105C2W	permease
D11S_2037	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D11S_2038	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D11S_2039	ENOG4105D9M	gamma-glutamylcysteine synthetase
D11S_2041	ENOG4108I6E	Sulfatase
D11S_2042	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D11S_2043	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D11S_2046	ENOG4105NX3	Membrane
D11S_2047	ENOG4105C59	p-type ATPase
D11S_2049	ENOG4108Z6Z	Transcriptional regulator
D11S_2050	ENOG4105CVR	type I restriction-modification system
D11S_2051	ENOG4105DZR	Type I site-specific deoxyribonuclease
D11S_2052	ENOG4108R96	Methyltransferase, YaeB family
D11S_2053	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
D11S_2057	ENOG4105N42	UPF0307 protein
D11S_2058	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D11S_2059	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D11S_2060	ENOG4105BZW	Glycerate kinase
D11S_2061	ENOG4107QQ0	gntp family
D11S_2062	ENOG4107VHA	regulatoR
D11S_2064	ENOG4105C1J	atp-dependent rna helicase
D11S_2065	ENOG4105RT1	May be involved in cell division (By similarity)
D11S_2067	ENOG4108R66	Conserved Protein
D11S_2069	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
D11S_2071	ENOG4107QHF	type ii secretion system protein e
D11S_2072	ENOG4105D7Q	type ii secretion system
D11S_2075	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
D11S_2077	ENOG4105BZG	amino acid carrier protein
D11S_2078	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
D11S_2080	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D11S_2081	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D11S_2083	ENOG4105MZU	cell filamentation protein
D11S_2084	ENOG4108IA2	Sodium pantothenate symporter
D11S_2085	ENOG4105RG0	Membrane
D11S_2089	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D11S_2090	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D11S_2093	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
D11S_2096	ENOG4108IPT	Naphthoate synthase
D11S_2098	ENOG4108HYK	gCN5-related N-acetyltransferase
D11S_2099	ENOG4105D4P	Coproporphyrinogen iii oxidase
D11S_2100	ENOG4105XCT	Protein of unknown function (DUF2489)
D11S_2101	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
D11S_2102	ENOG4108Z6B	deaminase
D11S_2103	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D11S_2105	ENOG4105HF0	Membrane
D11S_2106	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D11S_2107	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
D11S_2108	ENOG4105C2J	ABC transporter
D11S_2109	ENOG4105CNN	ABC, transporter
D11S_2110	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D11S_2111	ENOG4108RVA	ribokinase
D11S_2112	ENOG4105VEQ	Cold shock protein
D11S_2118	ENOG4108ST3	glycosyltransferase
D11S_2119	ENOG4105CH7	arginosuccinase
D11S_2120	ENOG4105D82	Glutamate dehydrogenase
D11S_2121	ENOG4105CH6	catalase
D11S_2123	ENOG4105C0B	DNA polymerase III (alpha subunit)
D11S_2125	ENOG4108IQE	Amp-dependent synthetase and ligase
D11S_2128	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
D11S_2131	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
D11S_2132	ENOG4105EYA	deoxyribonuclease
D11S_2135	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D11S_2137	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D11S_2140	ENOG4105DZ1	carboxypeptidase
D11S_2141	ENOG4105K6T	rare lipoprotein A
D11S_2142	ENOG4105CNI	cell division protein FtsW
D11S_2143	ENOG4105CJN	penicillin-binding protein
D11S_2145	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D11S_2146	ENOG4105C1J	atp-dependent rna helicase
D11S_2147	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D11S_2148	ENOG4107RGD	Major Facilitator superfamily
D11S_2151	ENOG4105CHR	reductase
D11S_2152	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D11S_2154	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D11S_2155	ENOG4105VGS	50s ribosomal protein l32
D11S_2156	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
D11S_2157	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D11S_2158	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D11S_2165	ENOG4107H6E	
D11S_2179	ENOG41067KA	Domain of unknown function (DUF1834)
D11S_2180	ENOG4105Y5J	prophage protein
D11S_2182	ENOG4105EFV	Major head subunit
D11S_2183	ENOG4108TVE	i protein
D11S_2184	ENOG4105ZS4	g protein
D11S_2185	ENOG4108QUU	Morphogenesis Protein
D11S_2186	ENOG4105QIB	mu-like prophage Flumu protein gp29
D11S_2187	ENOG4105CF2	Mu-like prophage FluMu protein GP28
D11S_2188	ENOG4108Z6H	mu-like prophage Flumu protein gp27
D11S_2197	ENOG4105ZIA	Phage protein gp16
D11S_2198	ENOG41065S5	
D11S_2225	ENOG4106GMR	
D11S_2230	ENOG41090AG	Bacteriophage protein
D11S_2231	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D11S_2233	ENOG4108C66	Inherit from COG: DNA primase
D11S_2234	ENOG4107ZQ5	Phage-associated protein, HI1409 family
D11S_2236	ENOG41061CV	Terminase small subunit 
D11S_2240	ENOG4105NVB	glycoside hydrolase, family 19
D11S_2244	ENOG4105WXW	Antirepressor
D11S_2248	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D11S_2253	ENOG4105CAR	Terminase, large subunit
D11S_2263	ENOG4105WXW	Antirepressor
D11S_2273	ENOG4108KU3	Integrase
D11S_2289	ENOG4105CMA	conjugation trbi family protein
D11S_2301	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D11S_2320	ENOG4108UUM	single-stranded DNA-binding protein
D11S_2321	ENOG4108C33	Resolvase