locus-tag	class	description
CF65_00002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CF65_00003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CF65_00004	ENOG4105DVA	methyltransferase
CF65_00007	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CF65_00010	ENOG4105DQ6	Transposase
CF65_00015	ENOG4105C6K	Malic enzyme
CF65_00021	ENOG41088T4	Helicase IV
CF65_00029	ENOG4107QMH	DNA methylase
CF65_00038	ENOG4105CBX	hi0933 family
CF65_00039	ENOG4108DMF	Cytochrome C biogenesis protein
CF65_00040	ENOG4107QX9	Thiol disulfide interChange protein
CF65_00041	ENOG4105DA4	cytochrome c-type biogenesis protein
CF65_00043	ENOG4105DVI	reductase, NrfD
CF65_00044	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CF65_00046	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
CF65_00050	ENOG4108M1T	Cytochrome c-type biogenesis protein
CF65_00052	ENOG4108M1T	Cytochrome c-type biogenesis protein
CF65_00054	ENOG4107QX9	Thiol disulfide interChange protein
CF65_00055	ENOG4105DA4	cytochrome c-type biogenesis protein
CF65_00056	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CF65_00057	ENOG4105X3C	heme exporter protein
CF65_00058	ENOG41060IM	Heme exporter protein
CF65_00059	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CF65_00061	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CF65_00062	ENOG4105C2C	drug resistance transporter, Bcr CflA
CF65_00064	ENOG4105I08	Pseudouridine synthase
CF65_00066	ENOG4105C6K	Malic enzyme
CF65_00068	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CF65_00071	ENOG4105CGZ	zinc metallopeptidase
CF65_00075	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CF65_00076	ENOG4107ZVW	dihydroneopterin aldolase
CF65_00077	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CF65_00079	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CF65_00080	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CF65_00081	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CF65_00084	ENOG4105CHM	Aminotransferase
CF65_00085	ENOG4105E4F	Isochorismate synthase
CF65_00086	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CF65_00087	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
CF65_00088	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CF65_00091	ENOG4105GPY	SprT protein
CF65_00092	ENOG4105C44	Serine transporter
CF65_00093	ENOG4105EJQ	L-serine dehydratase
CF65_00096	ENOG4105HDK	L-asparaginase
CF65_00101	ENOG41090FY	type IV pilus biogenesis stability protein PilW
CF65_00105	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
CF65_00106	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CF65_00107	ENOG4105CUT	histidyl-tRNA synthetase
CF65_00108	ENOG4105N21	Membrane
CF65_00110	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
CF65_00112	ENOG4105C2W	permease
CF65_00113	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CF65_00114	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CF65_00115	ENOG4105D9M	gamma-glutamylcysteine synthetase
CF65_00116	ENOG4108I6E	Sulfatase
CF65_00119	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CF65_00120	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CF65_00126	ENOG4105NX3	Membrane
CF65_00128	ENOG4105C59	p-type ATPase
CF65_00131	ENOG4108Z6Z	Transcriptional regulator
CF65_00132	ENOG4108R96	Methyltransferase, YaeB family
CF65_00134	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CF65_00135	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CF65_00136	ENOG4105C8P	)-transporter
CF65_00137	ENOG4105N42	UPF0307 protein
CF65_00139	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CF65_00141	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CF65_00142	ENOG4105BZW	Glycerate kinase
CF65_00143	ENOG4107QQ0	gntp family
CF65_00144	ENOG4107VHA	regulatoR
CF65_00145	ENOG4105DQ6	Transposase
CF65_00146	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
CF65_00148	ENOG4105C1J	atp-dependent rna helicase
CF65_00150	ENOG4105RT1	May be involved in cell division (By similarity)
CF65_00153	ENOG4108R66	Conserved Protein
CF65_00158	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
CF65_00161	ENOG4107QHF	type ii secretion system protein e
CF65_00162	ENOG4105D7Q	type ii secretion system
CF65_00165	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
CF65_00167	ENOG4105BZG	amino acid carrier protein
CF65_00168	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
CF65_00171	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CF65_00172	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CF65_00175	ENOG4105MZU	cell filamentation protein
CF65_00176	ENOG4108IA2	Sodium pantothenate symporter
CF65_00177	ENOG4105RG0	Membrane
CF65_00182	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CF65_00183	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CF65_00185	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CF65_00186	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
CF65_00189	ENOG4108IPT	Naphthoate synthase
CF65_00191	ENOG4108HYK	gCN5-related N-acetyltransferase
CF65_00194	ENOG4105D4P	Coproporphyrinogen iii oxidase
CF65_00195	ENOG4105XCT	Protein of unknown function (DUF2489)
CF65_00196	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CF65_00198	ENOG4108Z6B	deaminase
CF65_00200	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CF65_00202	ENOG4105HF0	Membrane
CF65_00204	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CF65_00205	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CF65_00207	ENOG4105C2J	ABC transporter
CF65_00208	ENOG4105CNN	ABC, transporter
CF65_00209	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CF65_00212	ENOG4108RVA	ribokinase
CF65_00213	ENOG4105VEQ	Cold shock protein
CF65_00216	ENOG4108ST3	glycosyltransferase
CF65_00218	ENOG4105CH7	arginosuccinase
CF65_00221	ENOG4105D82	Glutamate dehydrogenase
CF65_00223	ENOG4105CH6	catalase
CF65_00229	ENOG4105C0B	DNA polymerase III (alpha subunit)
CF65_00231	ENOG4108IQE	Amp-dependent synthetase and ligase
CF65_00236	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CF65_00241	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CF65_00244	ENOG4105EYA	deoxyribonuclease
CF65_00247	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CF65_00250	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CF65_00254	ENOG4105DZ1	carboxypeptidase
CF65_00256	ENOG4105K6T	rare lipoprotein A
CF65_00257	ENOG4105CNI	cell division protein FtsW
CF65_00258	ENOG4105CJN	penicillin-binding protein
CF65_00260	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CF65_00263	ENOG4105C1J	atp-dependent rna helicase
CF65_00265	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CF65_00266	ENOG4107RGD	Major Facilitator superfamily
CF65_00269	ENOG4105CHR	reductase
CF65_00270	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CF65_00273	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CF65_00274	ENOG4105VGS	50s ribosomal protein l32
CF65_00275	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CF65_00276	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CF65_00277	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CF65_00278	ENOG4105HSA	Protein of unknown function (DUF452)
CF65_00279	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CF65_00280	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CF65_00281	ENOG4105DJ4	phosphatidylserine decarboxylase
CF65_00282	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CF65_00283	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CF65_00286	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CF65_00287	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CF65_00288	ENOG4105DWK	Membrane
CF65_00290	ENOG4107XM3	UPF0442 protein
CF65_00292	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CF65_00296	ENOG4105C37	(CBS) domain
CF65_00300	ENOG4105RX8	Protein of unknown function (DUF1523)
CF65_00301	ENOG4105F8V	Hydrolase, tatD family
CF65_00302	ENOG4107QRG	dna polymerase iii
CF65_00303	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CF65_00305	ENOG4105HHA	aminodeoxychorismate lyase
CF65_00306	ENOG4108YZA	Nitrogen regulatory protein pii
CF65_00308	ENOG4105MVE	transcriptional regulator
CF65_00309	ENOG4105ZXK	Dehydrogenase
CF65_00310	ENOG4105G63	Type III effector Hrp-dependent
CF65_00311	ENOG4105FB2	class II Aldolase
CF65_00312	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
CF65_00316	ENOG4108K4B	hydrolase
CF65_00317	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CF65_00323	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CF65_00324	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CF65_00325	ENOG4108WFC	UPF0438 protein yifE
CF65_00326	ENOG4108Z33	Thiol disulfide Interchange Protein
CF65_00329	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CF65_00332	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CF65_00333	ENOG4105DE4	1-phosphofructokinase
CF65_00335	ENOG4105DM4	PTS System
CF65_00344	ENOG4105PM1	preprotein translocase subunit SecE
CF65_00345	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CF65_00350	ENOG4108VZM	50s ribosomal protein L10
CF65_00355	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CF65_00356	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CF65_00357	ENOG4108RS6	transposase
CF65_00358	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CF65_00359	ENOG41083MP	50s ribosomal protein l29
CF65_00361	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CF65_00362	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CF65_00363	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CF65_00365	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CF65_00366	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CF65_00368	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CF65_00369	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CF65_00371	ENOG4105CMU	LysR family (Transcriptional regulator
CF65_00372	ENOG4107QP7	CoA-transferase subunit A
CF65_00373	ENOG4107QNJ	CoA-transferase subunit B
CF65_00374	ENOG4105CRW	Short chain fatty acid transporter
CF65_00377	ENOG4105CHU	acetyl-coa acetyltransferase
CF65_00378	ENOG4105EW9	transcriptional regulator AsnC family
CF65_00379	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CF65_00380	ENOG4105C5B	carbamate kinase
CF65_00381	ENOG4105DBV	ornithine carbamoyltransferase
CF65_00384	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CF65_00387	ENOG4108VVK	transcriptional Regulator, AsnC
CF65_00388	ENOG4108I5U	Uridine phosphorylase
CF65_00391	ENOG4105K89	arsenate reductase
CF65_00397	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CF65_00398	ENOG4105KJF	protein tyrosine phosphatase
CF65_00399	ENOG4105Z2P	Protein of unknown function (DUF465)
CF65_00401	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CF65_00404	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
CF65_00407	ENOG4105C1A	potassium transporter peripheral membrane
CF65_00408	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CF65_00414	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CF65_00415	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CF65_00417	ENOG4105D01	(LipO)protein
CF65_00420	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CF65_00422	ENOG4108MJ5	VirK protein
CF65_00423	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CF65_00425	ENOG4105C0P	Mg chelatase subunit ChlI
CF65_00426	ENOG4105C0P	Mg chelatase subunit ChlI
CF65_00434	ENOG4105CS6	Rhs element vgr protein
CF65_00448	ENOG4105C0P	Mg chelatase subunit ChlI
CF65_00449	ENOG4105PXI	polysaccharide deacetylase
CF65_00450	ENOG41063SB	peptidase
CF65_00452	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
CF65_00453	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CF65_00454	ENOG4105XWI	UPF0304 protein
CF65_00455	ENOG410903C	(LipO)protein
CF65_00458	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
CF65_00460	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CF65_00468	ENOG4105CIC	tryptophan-specific transport protein
CF65_00469	ENOG4105F0N	pyrophosphate phospho-hydrolase
CF65_00470	ENOG4105ERG	peptidase m48, ste24p
CF65_00471	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CF65_00473	ENOG4105C31	Tryptophanyl-tRNA synthetase
CF65_00474	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CF65_00475	ENOG4106H78	methyltransferase
CF65_00478	ENOG4108EQA	pts system
CF65_00479	ENOG4105ETZ	PTS System
CF65_00480	ENOG4105F3R	pts system mannose fructose sorbose family iid
CF65_00482	ENOG410667J	hydrolase
CF65_00486	ENOG4105D9N	nucleoside
CF65_00491	ENOG4107BJW	polysaccharide deacetylase
CF65_00492	ENOG4105CND	Glycosyl transferase, family 2
CF65_00497	ENOG4105CXY	transporter
CF65_00506	ENOG4105C1J	atp-dependent rna helicase
CF65_00508	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CF65_00513	ENOG4105D3G	Pseudouridine synthase
CF65_00518	ENOG4105W39	Membrane
CF65_00519	ENOG4108UW5	maltose o-acetyltransferase
CF65_00521	ENOG4107VXZ	Hydrolase
CF65_00527	ENOG4105C4R	Atp-dependent dna helicase
CF65_00531	ENOG4105C2M	dna polymerase I
CF65_00536	ENOG4105CGH	5'-nucleotidase
CF65_00537	ENOG4106W3N	
CF65_00539	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CF65_00543	ENOG4105XA0	heptosyltransferase ii
CF65_00544	ENOG4106032	Glutathionylspermidine synthase
CF65_00545	ENOG4106032	Glutathionylspermidine synthase
CF65_00546	ENOG4105CUW	cytochrome C-TYPE protein
CF65_00547	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
CF65_00549	ENOG4105GXZ	Ferredoxin-type protein NapH
CF65_00550	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CF65_00557	ENOG4105BZU	Histidine kinase
CF65_00558	ENOG4105D4A	Cell wall formation (By similarity)
CF65_00560	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CF65_00563	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CF65_00565	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CF65_00566	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CF65_00569	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CF65_00573	ENOG4105DTR	rard protein
CF65_00575	ENOG4105E2X	shikimate dehydrogenase
CF65_00576	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CF65_00578	ENOG4108WI1	Dna topoisomerase
CF65_00579	ENOG4105CGY	Dna recombination protein
CF65_00580	ENOG4108TEB	UPF0114 protein
CF65_00581	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CF65_00583	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
CF65_00585	ENOG4105E98	transcriptional regulator DeoR family
CF65_00586	ENOG4105E98	transcriptional regulator DeoR family
CF65_00590	ENOG41063SR	receptor
CF65_00591	ENOG4105CQ0	ABC transporter
CF65_00592	ENOG4105D0C	transport protein
CF65_00600	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CF65_00602	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CF65_00603	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CF65_00605	ENOG4105KNE	Phosphatidate cytidylyltransferase
CF65_00606	ENOG4105DZP	Membrane-associated zinc metalloprotease
CF65_00608	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF65_00610	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CF65_00611	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CF65_00612	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CF65_00613	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CF65_00615	ENOG4107QWE	)-transporter
CF65_00616	ENOG4108HPI	phosphatidate Cytidylyltransferase
CF65_00618	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CF65_00628	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CF65_00629	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CF65_00634	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CF65_00635	ENOG4105EEI	dihydropteroate synthase
CF65_00637	ENOG4108BY2	phosphohistidine phosphatase
CF65_00641	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CF65_00644	ENOG4107TT5	NLP P60 protein
CF65_00646	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CF65_00647	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CF65_00649	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CF65_00650	ENOG4108XTF	Outer Membrane Lipoprotein
CF65_00651	ENOG4105NBI	YecM protein
CF65_00652	ENOG4105C75	arginyL-tRNA synthetase
CF65_00654	ENOG4106J39	exported protein
CF65_00657	ENOG4105CFG	Acts as a chaperone (By similarity)
CF65_00659	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CF65_00662	ENOG4105C28	cystathionine
CF65_00663	ENOG4105C28	cystathionine
CF65_00664	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CF65_00668	ENOG4108TMH	cytolethal distending toxin
CF65_00669	ENOG4106BMH	cytolethal distending toxin
CF65_00674	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CF65_00675	ENOG4105E9S	glutaredoxin 2
CF65_00679	ENOG4105C03	ribonuclease
CF65_00680	ENOG4105CK7	Sodium proline symporter
CF65_00684	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CF65_00689	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CF65_00691	ENOG4105F27	Major Facilitator
CF65_00696	ENOG4105C4Y	ABC transporter
CF65_00698	ENOG4105C4Y	ABC transporter
CF65_00699	ENOG4107RCV	ABC transporter, permease
CF65_00700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CF65_00705	ENOG4105ECY	inositol monophosphatase
CF65_00706	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CF65_00707	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CF65_00709	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CF65_00711	ENOG4108Z4V	iron-sulfur cluster assembly
CF65_00712	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CF65_00713	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CF65_00715	ENOG4108ZIT	Ferredoxin, 2FE-2S
CF65_00716	ENOG4105WVQ	Fe-S assembly protein IscX
CF65_00717	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CF65_00718	ENOG4105D1F	ATP-binding protein
CF65_00721	ENOG4105E2D	ec 3.2.1.52
CF65_00722	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CF65_00723	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CF65_00726	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CF65_00729	ENOG4108JU5	Magnesium and cobalt efflux protein
CF65_00732	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
CF65_00735	ENOG4105CI0	Citrate lyase
CF65_00737	ENOG4105CHY	citrate lyase, alpha
CF65_00740	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
CF65_00741	ENOG4107QPK	)-transporter
CF65_00744	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CF65_00745	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CF65_00747	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CF65_00749	ENOG41060NJ	transcriptional regulator
CF65_00750	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
CF65_00753	ENOG4108HWV	)-transporter
CF65_00757	ENOG4105BZU	Histidine kinase
CF65_00759	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CF65_00760	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CF65_00761	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CF65_00766	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CF65_00769	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CF65_00770	ENOG4105EIF	outer membrane protein W
CF65_00774	ENOG4107835	probably involved in intracellular septation (By similarity)
CF65_00775	ENOG4105NAU	thioesterase Superfamily protein
CF65_00776	ENOG4105K9H	YciI-like protein
CF65_00777	ENOG4107SC1	transglycosylase
CF65_00778	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
CF65_00780	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CF65_00785	ENOG4105DFP	Integrase
CF65_00789	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CF65_00790	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CF65_00792	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CF65_00794	ENOG4105DIN	metallophosphoesterase
CF65_00795	ENOG4108HUF	Transporter
CF65_00796	ENOG4105DQ5	transport system permease protein
CF65_00798	ENOG4108IHU	transport system permease protein
CF65_00799	ENOG4105E0A	ABC, transporter
CF65_00801	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CF65_00804	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CF65_00805	ENOG4105E33	succinate dehydrogenase
CF65_00806	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CF65_00807	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CF65_00809	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CF65_00812	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CF65_00816	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CF65_00817	ENOG41087AY	ADP-Ribose pyrophosphatase
CF65_00822	ENOG4105KUZ	arsenate reductase
CF65_00823	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CF65_00825	ENOG4105CQC	Prephenate dehydratase
CF65_00827	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CF65_00830	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CF65_00831	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CF65_00832	ENOG4105CPF	Cell wall formation (By similarity)
CF65_00833	ENOG4105DFU	Cell wall formation (By similarity)
CF65_00835	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CF65_00837	ENOG4105CNI	cell division protein FtsW
CF65_00838	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CF65_00839	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CF65_00840	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CF65_00841	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CF65_00844	ENOG4105CJN	penicillin-binding protein
CF65_00847	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CF65_00849	ENOG4108V6E	Cell division protein mraZ
CF65_00854	ENOG4105DMR	ABC, transporter
CF65_00855	ENOG4105GBT	ABC transporter
CF65_00856	ENOG4106PMH	Extracellular solute-binding protein family 3
CF65_00858	ENOG4105E5Z	arginine transporter ATP-binding subunit
CF65_00861	ENOG4108JA2	transcriptioN-repair coupling factor
CF65_00865	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CF65_00884	ENOG4105C8J	)-transporter
CF65_00885	ENOG4108R99	pseudouridine synthase
CF65_00892	ENOG4105EM7	Selenocysteine-specific translation elongation factor
CF65_00894	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
CF65_00896	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CF65_00899	ENOG4105KPY	Small multidrug resistance protein
CF65_00900	ENOG4105Y75	tpr repeat protein
CF65_00902	ENOG4105EMN	RNA polymerase sigma factor
CF65_00904	ENOG41069PW	sigma-e factor negative regulatory protein
CF65_00906	ENOG4105VQK	sigma E regulatory protein, MucB RseB
CF65_00908	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
CF65_00909	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
CF65_00912	ENOG4108IXY	short-chain dehydrogenase reductase
CF65_00914	ENOG4105CIN	aminoacyl-histidine dipeptidase
CF65_00919	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CF65_00920	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CF65_00921	ENOG4105R3P	Inner membrane protein yagU
CF65_00923	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CF65_00926	ENOG4105XQ6	frataxin-like protein
CF65_00927	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CF65_00929	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CF65_00930	ENOG4105CS9	pantothenic acid kinase
CF65_00931	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CF65_00932	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CF65_00933	ENOG4105C2J	ABC transporter
CF65_00934	ENOG4105C2J	ABC transporter
CF65_00935	ENOG4105CNN	ABC, transporter
CF65_00936	ENOG4105CNN	ABC, transporter
CF65_00937	ENOG4105CMG	Carbohydrate kinase
CF65_00938	ENOG4105CMG	Carbohydrate kinase
CF65_00939	ENOG4105BZM	domain protein
CF65_00941	ENOG4107QPK	)-transporter
CF65_00942	ENOG4108TGR	phosphatase
CF65_00943	ENOG4105BZM	domain protein
CF65_00944	ENOG4108RRZ	Transcription elongation factor GreB
CF65_00948	ENOG4108WQI	RNA Polymerase
CF65_00950	ENOG4105EX9	Membrane
CF65_00952	ENOG410601J	HemY protein
CF65_00953	ENOG4105ECF	c-methyltransferase
CF65_00957	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CF65_00958	ENOG4107T0K	Adenylate cyclase
CF65_00959	ENOG4105WH1	Two component transcriptional regulator luxr family
CF65_00960	ENOG4105CFU	surface antigen
CF65_00961	ENOG4105MA0	exported protein
CF65_00962	ENOG4105C9X	ppx gppa phosphatase
CF65_00970	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CF65_00971	ENOG4105R2J	Conserved Protein
CF65_00972	ENOG4105K70	DNA-binding protein
CF65_00973	ENOG410804X	Transcriptional regulator
CF65_00974	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CF65_00976	ENOG4105ENX	hydrolase
CF65_00977	ENOG4105EQ2	LysR family Transcriptional regulator
CF65_00981	ENOG4105EBR	Carboxylesterase
CF65_00982	ENOG4105CPC	Aldo Keto reductase
CF65_00985	ENOG4105EQ2	LysR family Transcriptional regulator
CF65_00988	ENOG4105D7A	ATP-binding protein
CF65_00991	ENOG4105K5B	UPF0225 protein
CF65_00992	ENOG4107S2Z	UPF0761 membrane protein
CF65_00994	ENOG4105D6U	Sodium Glutamate Symporter
CF65_00995	ENOG4105E0F	Histidine kinase
CF65_00997	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CF65_00998	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CF65_01003	ENOG4105YDX	UPF0352 protein
CF65_01005	ENOG4105E68	Sulfatase
CF65_01008	ENOG4105DXN	mazG family
CF65_01009	ENOG4108M6U	Universal stress protein A
CF65_01011	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CF65_01012	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CF65_01013	ENOG4107QKV	phosphomannomutase
CF65_01014	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CF65_01015	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CF65_01017	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CF65_01018	ENOG4108UJU	UPF0301 protein
CF65_01019	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CF65_01020	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CF65_01022	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CF65_01024	ENOG4105CJ2	(LipO)protein
CF65_01027	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CF65_01028	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CF65_01029	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CF65_01031	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CF65_01039	ENOG4105M85	Bola protein
CF65_01040	ENOG4105IEY	(LipO)protein
CF65_01042	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CF65_01043	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CF65_01044	ENOG4105CEN	a g-specific adenine glycosylase
CF65_01045	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CF65_01046	ENOG41090ED	Protein with unknown function (DUF469)
CF65_01048	ENOG4107QKW	extracellular solute-binding protein family 1
CF65_01050	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
CF65_01051	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CF65_01053	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CF65_01054	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CF65_01056	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CF65_01057	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CF65_01059	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CF65_01062	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CF65_01063	ENOG4105DSJ	YicC domain protein
CF65_01064	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CF65_01069	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CF65_01070	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CF65_01071	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CF65_01072	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CF65_01074	ENOG41080IJ	Diacylglycerol kinase
CF65_01077	ENOG4105DQ6	Transposase
CF65_01078	ENOG4105W1Y	Transcriptional regulator
CF65_01083	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CF65_01085	ENOG4105M6F	mutator MutT protein
CF65_01087	ENOG4105DJF	DNA polymerase III, delta' subunit
CF65_01095	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
CF65_01096	ENOG41060A7	DNA polymerase beta domain protein region
CF65_01097	ENOG41062MS	nucleotidyltransferase substrate binding protein
CF65_01098	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CF65_01099	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CF65_01101	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CF65_01102	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
CF65_01106	ENOG41075W9	High frequency lysogenization protein HflD homolog
CF65_01107	ENOG4107QTF	adenylosuccinate lyase
CF65_01109	ENOG4105EMU	Dehydrogenase
CF65_01111	ENOG4105VUF	Transcriptional regulator
CF65_01113	ENOG4105VUF	Transcriptional regulator
CF65_01114	ENOG4107QPD	alcohol dehydrogenase
CF65_01115	ENOG4105C4W	S-formylglutathione hydrolase
CF65_01117	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CF65_01120	ENOG4106KVJ	cytochrome C assembly protein
CF65_01123	ENOG4108JU6	CBS domain protein
CF65_01124	ENOG4105M8K	biopolymer transport protein
CF65_01127	ENOG41067XB	TonB family
CF65_01137	ENOG4107QY8	reductase
CF65_01138	ENOG4105QAX	Iron-sulfur
CF65_01140	ENOG4107KGK	dmso reductase anchor subunit
CF65_01141	ENOG4108NEM	leader-binding protein dmsD
CF65_01146	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
CF65_01151	ENOG4105D52	delta-aminolevulinic acid dehydratase
CF65_01152	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CF65_01153	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CF65_01154	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CF65_01156	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CF65_01158	ENOG4105VEJ	Heat shock protein
CF65_01159	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
CF65_01160	ENOG4107RK2	ADP-ribose diphosphatase NudE
CF65_01161	ENOG4105E7U	AraC family transcriptional regulator
CF65_01162	ENOG4108KBJ	Inner membrane protein YkgB
CF65_01164	ENOG4105EPD	Oligopeptide transporter, Opt family
CF65_01166	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CF65_01167	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CF65_01168	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CF65_01172	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
CF65_01177	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CF65_01179	ENOG4105C2D	reductase
CF65_01182	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CF65_01195	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CF65_01201	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CF65_01202	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CF65_01203	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CF65_01206	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CF65_01211	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CF65_01213	ENOG4105KQC	Competence protein
CF65_01215	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CF65_01216	ENOG4108X4Q	Hydrolase
CF65_01220	ENOG4105MJ2	Competence protein
CF65_01221	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CF65_01222	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CF65_01223	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CF65_01224	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CF65_01226	ENOG4108RS6	transposase
CF65_01228	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CF65_01229	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CF65_01230	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CF65_01232	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CF65_01233	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CF65_01234	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
CF65_01235	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CF65_01237	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CF65_01238	ENOG41067V7	50S ribosomal protein L36
CF65_01241	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CF65_01242	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CF65_01243	ENOG4108ZT0	50S ribosomal protein l17
CF65_01244	ENOG4108RS6	transposase
CF65_01245	ENOG4105E0U	tyrosine-specific transport protein
CF65_01249	ENOG4108VVQ	metallophosphoesterase
CF65_01250	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
CF65_01252	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CF65_01254	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CF65_01258	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CF65_01259	ENOG4108RR8	protoporphyrinogen oxidase
CF65_01264	ENOG4108UUE	Transcriptional regulator
CF65_01265	ENOG4108UUE	Transcriptional regulator
CF65_01268	ENOG4105DQ6	Transposase
CF65_01273	ENOG4108VW9	Membrane
CF65_01276	ENOG4105M5K	heptosyltransferase
CF65_01277	ENOG4108IJ0	Aspartate ammonia-lyase
CF65_01280	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CF65_01284	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CF65_01286	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CF65_01287	ENOG4105DQ6	Transposase
CF65_01291	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CF65_01292	ENOG4108UUM	single-stranded DNA-binding protein
CF65_01294	ENOG4105DFE	Dna adenine methylase
CF65_01295	ENOG4105D49	3-dehydroquinate synthase
CF65_01296	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CF65_01297	ENOG4105E4G	Type IV pilus
CF65_01304	ENOG4108JQC	penicillin-binding protein 1A
CF65_01305	ENOG4105D6S	protein involved in catabolism of external DNA
CF65_01306	ENOG4105DC8	reductase
CF65_01308	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CF65_01310	ENOG4105YP7	UPF0270 protein
CF65_01311	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CF65_01315	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CF65_01319	ENOG4105M7P	phage repressor
CF65_01324	ENOG4105W0E	50S ribosomal protein L33
CF65_01330	ENOG4105W1T	Glycosyl Transferase
CF65_01332	ENOG4105W1T	Glycosyl Transferase
CF65_01334	ENOG4108SEH	involved in lipopolysaccharide biosynthesis
CF65_01335	ENOG4105C25	Primosomal protein n'
CF65_01337	ENOG41063M6	Cell Division Protein
CF65_01339	ENOG4105Y7M	Transcriptional regulator, TetR family
CF65_01340	ENOG410624X	efflux transporter, rnd family, mfp subunit
CF65_01341	ENOG4105BZS	acriflavin resistance protein
CF65_01342	ENOG4108BSC	Methyltransferase
CF65_01344	ENOG4107QUT	magnesium and cobalt transport protein CorA
CF65_01345	ENOG4108VIA	integral membrane protein
CF65_01347	ENOG4105VZ9	UPF0235 protein
CF65_01349	ENOG4108RCM	Nitroreductase
CF65_01351	ENOG4105E0M	Sulfatase
CF65_01354	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CF65_01355	ENOG4105C34	Pseudouridine synthase
CF65_01356	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CF65_01357	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CF65_01358	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CF65_01359	ENOG4105E07	UPF0149 protein
CF65_01360	ENOG4107RAQ	aminopeptidase
CF65_01370	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CF65_01371	ENOG4105DFF	Rod shape-determining protein mreb
CF65_01372	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CF65_01374	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CF65_01378	ENOG4105CXY	transporter
CF65_01379	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CF65_01383	ENOG4105C79	DNA protecting protein DprA
CF65_01385	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CF65_01388	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CF65_01390	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CF65_01391	ENOG4105E55	glycerol-3-phosphate acyltransferase
CF65_01393	ENOG4105BZ1	(ABC) transporter
CF65_01394	ENOG4105E7U	AraC family transcriptional regulator
CF65_01396	ENOG4105DKP	glycosyl transferase, family 9
CF65_01401	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CF65_01402	ENOG4106WTF	Glycosyl transferase, family 2
CF65_01407	ENOG4108K5P	(LipO)protein
CF65_01409	ENOG4108UM1	dedA family
CF65_01411	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CF65_01413	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CF65_01417	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CF65_01418	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CF65_01419	ENOG4105DJV	ribulose-phosphate 3-epimerase
CF65_01421	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CF65_01422	ENOG4105CAK	Cell division ATP-binding protein ftsE
CF65_01423	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CF65_01424	ENOG4105C7B	Threonine dehydratase
CF65_01426	ENOG4105C7B	Threonine dehydratase
CF65_01431	ENOG4105DQF	Hydrolase
CF65_01432	ENOG4108EUD	Lysophospholipase
CF65_01434	ENOG4105PF3	O-Antigen polymerase
CF65_01436	ENOG4105D2N	Aldolase
CF65_01438	ENOG41083KI	ribonuclease, T2
CF65_01439	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CF65_01441	ENOG4105EIB	trna rrna methyltransferase
CF65_01442	ENOG4105JIM	Phosphatidylserine synthase
CF65_01444	ENOG4105DQ6	Transposase
CF65_01451	ENOG4105CMG	Carbohydrate kinase
CF65_01453	ENOG4105C93	Xylose Isomerase
CF65_01455	ENOG4105DFW	ABC transporter
CF65_01456	ENOG4105C2J	ABC transporter
CF65_01457	ENOG4108HWW	ABC transporter
CF65_01458	ENOG4105C87	Aminotransferase class I and II
CF65_01459	ENOG4105DFD	Na H antiporter
CF65_01462	ENOG4105T16	Transcriptional regulator (AraC family)
CF65_01463	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CF65_01465	ENOG4108EQA	pts system
CF65_01466	ENOG4105ETZ	PTS System
CF65_01467	ENOG4105F3R	pts system mannose fructose sorbose family iid
CF65_01473	ENOG4105EKX	Restriction modification system DNA (Specificity
CF65_01479	ENOG4107RUE	extracellular solute-binding protein family 1
CF65_01480	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CF65_01484	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CF65_01487	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CF65_01492	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CF65_01494	ENOG4105KVH	Transcriptional regulator
CF65_01495	ENOG4105ECR	NmrA family
CF65_01497	ENOG4105QTB	Flavodoxin
CF65_01498	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
CF65_01499	ENOG4105CBT	Fructose-1,6-bisphosphatase
CF65_01502	ENOG4105D7W	serine acetyltransferase
CF65_01503	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CF65_01506	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CF65_01507	ENOG4107YZP	Rhodanese domain protein
CF65_01508	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CF65_01509	ENOG4108JJ9	ABC, transporter
CF65_01510	ENOG4105BZ1	(ABC) transporter
CF65_01511	ENOG4105EJ2	Transcriptional regulator
CF65_01513	ENOG4105C5Q	Transcriptional regulator
CF65_01514	ENOG4105EHV	domain protein
CF65_01515	ENOG4105VRX	Protein slyX homolog
CF65_01517	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CF65_01519	ENOG4105WWK	YheO domain protein
CF65_01522	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CF65_01524	ENOG4105CDA	abc transporter atp-binding protein
CF65_01525	ENOG4105E5Q	amino acid AbC transporter
CF65_01526	ENOG4105EAB	amino acid AbC transporter
CF65_01528	ENOG4105CJP	fad dependent oxidoreductase
CF65_01537	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CF65_01538	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CF65_01539	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CF65_01546	ENOG4107FB0	transcriptional regulator DeoR family
CF65_01549	ENOG4105IYK	transposase
CF65_01552	ENOG410689M	(LipO)protein
CF65_01554	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CF65_01555	ENOG4105C5H	ABC transporter
CF65_01556	ENOG4105C5H	ABC transporter
CF65_01557	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CF65_01559	ENOG4105Y3E	Modulates RecA activity (By similarity)
CF65_01561	ENOG4105KME	endoribonuclease L-psp
CF65_01563	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CF65_01564	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CF65_01569	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CF65_01571	ENOG4108EU3	peptide transport system, permease
CF65_01573	ENOG4108EVY	peptide transport periplasmic protein
CF65_01575	ENOG4105CM6	amino acid regulated cytosolic protein
CF65_01577	ENOG4106K28	UPF0283 membrane protein
CF65_01579	ENOG4108JU8	Transcriptional regulator
CF65_01586	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CF65_01588	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CF65_01589	ENOG4105K8N	protein family UPF0079, ATPase
CF65_01593	ENOG410838F	Glycosyl transferase family 2
CF65_01594	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CF65_01596	ENOG4108I6E	Sulfatase
CF65_01599	ENOG4105KZ7	phosphocarrier protein hpr
CF65_01600	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CF65_01601	ENOG4105C5Y	PTS System
CF65_01603	ENOG4105DGW	oligopeptidase A
CF65_01604	ENOG4105WD1	Membrane
CF65_01607	ENOG4107TSG	Extracellular solute-binding protein, family 5
CF65_01609	ENOG4105CRQ	synthase (Component I)
CF65_01611	ENOG4105DDQ	anthranilate synthase
CF65_01614	ENOG4105C5I	Dehydrogenase
CF65_01615	ENOG4105D60	lipoprotein releasing system transmembrane protein
CF65_01616	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CF65_01618	ENOG4105D60	lipoprotein releasing system transmembrane protein
CF65_01619	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CF65_01621	ENOG4105CDU	Replicative dna helicase
CF65_01623	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CF65_01624	ENOG4107QP8	phosphohexose isomerase
CF65_01625	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CF65_01628	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CF65_01629	ENOG4108ZAI	phosphatidylglycerophosphatase a
CF65_01630	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
CF65_01633	ENOG4105XPH	Ferredoxin
CF65_01635	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CF65_01637	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CF65_01642	ENOG4105C4Y	ABC transporter
CF65_01644	ENOG4107RCV	ABC transporter, permease
CF65_01645	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CF65_01648	ENOG4107T9C	Alpha amylase catalytic region
CF65_01649	ENOG4105EG2	ABC transporter, permease
CF65_01650	ENOG4105D56	permease protein
CF65_01654	ENOG4107FKK	extracellular solute-binding protein family 1
CF65_01656	ENOG4108IJ9	(ABC) transporter
CF65_01657	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CF65_01658	ENOG4107W52	maltose operon periplasmic protein
CF65_01661	ENOG4105D06	uba thif-type nad fad binding protein
CF65_01662	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CF65_01663	ENOG4105EUJ	GTP cyclohydrolase i
CF65_01666	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
CF65_01668	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CF65_01670	ENOG4105HBR	Rna-binding protein
CF65_01671	ENOG4105VUH	addiction module killer protein
CF65_01672	ENOG4105YES	addiction module antidote protein
CF65_01673	ENOG4108R6K	riboflavin synthase, subunit alpha
CF65_01675	ENOG4107QI1	Mate efflux family protein
CF65_01678	ENOG4108Z66	YbaK ebsC protein
CF65_01679	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CF65_01681	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
CF65_01684	ENOG4108VEN	abc transporter atp-binding protein
CF65_01685	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CF65_01687	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CF65_01688	ENOG4105DN3	alpha-2-macroglobulin domain protein
CF65_01689	ENOG4105HMI	Membrane
CF65_01690	ENOG4108JQB	penicillin-binding protein 1C
CF65_01698	ENOG4105DW5	Transcriptional regulator
CF65_01700	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
CF65_01703	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
CF65_01704	ENOG4105E0U	tyrosine-specific transport protein
CF65_01705	ENOG4105CNT	hydrolase family 2
CF65_01708	ENOG41090BQ	Glutaredoxin
CF65_01709	ENOG4108DBC	nitroreductase
CF65_01711	ENOG4105D0Y	UPF0227 protein
CF65_01715	ENOG4105RHG	
CF65_01717	ENOG4105C9Q	fumarate hydratase class II
CF65_01718	ENOG4105MYG	DNA polymerase iii, chi subunit
CF65_01728	ENOG4105CAF	HipA N-terminal domain protein
CF65_01731	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CF65_01732	ENOG4105CW7	secretion protein, HlyD family
CF65_01734	ENOG4108RMU	ferritin dps family protein
CF65_01738	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
CF65_01739	ENOG4107QNR	UPF0135 protein
CF65_01740	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CF65_01741	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CF65_01743	ENOG4105CRK	lysyL-tRNA synthetase
CF65_01746	ENOG4105T95	Thiol disulfide interChange protein
CF65_01747	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CF65_01750	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CF65_01751	ENOG4105UZ0	ABC-type Co2 transport system, periplasmic component
CF65_01753	ENOG4108A51	
CF65_01755	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
CF65_01757	ENOG4108JJB	ABC transporter
CF65_01758	ENOG4107RSS	Hydrogenase accessory protein HypB
CF65_01759	ENOG4105CQS	hydrogenase expression formation protein HypD
CF65_01760	ENOG4105C45	hydrogenase expression formation protein (HypE)
CF65_01763	ENOG4105M7P	phage repressor
CF65_01765	ENOG4106YXT	transposase
CF65_01772	ENOG4105F9E	Shikimate 5-dehydrogenase
CF65_01774	ENOG4105SYT	Methylenetetrahydrofolate reductase
CF65_01776	ENOG4108K5H	permease YjgP YjgQ family protein
CF65_01777	ENOG4108M8S	permease YjgP YjgQ family protein
CF65_01778	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CF65_01779	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CF65_01780	ENOG4105E0C	molybdate abc transporter
CF65_01781	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CF65_01782	ENOG4105F4R	Transcriptional regulator mode
CF65_01784	ENOG4105C8P	)-transporter
CF65_01787	ENOG4105DK2	UPF0207 protein
CF65_01789	ENOG4105C0H	protease
CF65_01790	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CF65_01792	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CF65_01793	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CF65_01794	ENOG4105ETT	transcriptional Regulator, LysR family
CF65_01796	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CF65_01801	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CF65_01803	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CF65_01804	ENOG4105ECP	epimerase
CF65_01805	ENOG4105DGN	Electron transport complex
CF65_01807	ENOG4108R3D	Electron transport complex
CF65_01808	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CF65_01813	ENOG4105DZB	Electron transport complex
CF65_01814	ENOG4105CSM	endonuclease III
CF65_01815	ENOG4105C8J	)-transporter
CF65_01818	ENOG4105FAV	ABC, transporter
CF65_01820	ENOG4105FDK	ABC transporter
CF65_01822	ENOG4105DR5	peptidase
CF65_01824	ENOG4108IPW	abc transporter atp-binding protein
CF65_01825	ENOG4105CM4	permease protein
CF65_01826	ENOG4105DHS	permease protein
CF65_01830	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CF65_01835	ENOG4105H4F	exported protein
CF65_01837	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CF65_01841	ENOG4107H6E	
CF65_01842	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CF65_01843	ENOG4105DHQ	Histidine kinase
CF65_01845	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CF65_01846	ENOG4106CC8	Bacterial inner membrane protein
CF65_01848	ENOG4105CDH	Citrulline--aspartate ligase
CF65_01850	ENOG4108535	NAD dependent epimerase/dehydratase family
CF65_01852	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CF65_01854	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
CF65_01857	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CF65_01861	ENOG4105DWF	phosphomethylpyrimidine kinase
CF65_01865	ENOG4105DP9	ABC transporter
CF65_01866	ENOG4106SMU	thiamine transporter membrane protein
CF65_01867	ENOG4107T0D	ABC, transporter
CF65_01869	ENOG4105C0H	protease
CF65_01871	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
CF65_01872	ENOG4105DDY	UPF0142 protein ycaO
CF65_01873	ENOG4105EIP	mannose-6-phosphate isomerase
CF65_01874	ENOG4105KWI	UPF0339 protein
CF65_01875	ENOG4105CI1	PTS System
CF65_01876	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
CF65_01878	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CF65_01880	ENOG4105E2R	ROK family
CF65_01881	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CF65_01883	ENOG4105EYM	Major Facilitator superfamily
CF65_01885	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
CF65_01886	ENOG4105CMR	udp-glucose 4-epimerase
CF65_01887	ENOG4105KAF	membrAne
CF65_01889	ENOG4105C7N	Xanthine uracil vitamin C permease
CF65_01890	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CF65_01891	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CF65_01893	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CF65_01894	ENOG4105VT2	5-hydroxyisourate hydrolase
CF65_01906	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CF65_01918	ENOG4105CEE	C4-dicarboxylate transporter
CF65_01919	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CF65_01920	ENOG4105CHV	Transcription elongation factor NusA
CF65_01922	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CF65_01923	ENOG4107QMH	DNA methylase
CF65_01928	ENOG4105C0D	helicase
CF65_01930	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CF65_01936	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CF65_01938	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CF65_01939	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CF65_01947	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CF65_01954	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CF65_01957	ENOG41085JB	UPF0434 protein
CF65_01959	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CF65_01961	ENOG4105BZ1	(ABC) transporter
CF65_01962	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
CF65_01963	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
CF65_01965	ENOG4105DJ0	Poly(A) Polymerase
CF65_01966	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CF65_01972	ENOG4108DNC	Involved in acetate metabolism (By similarity)
CF65_01973	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CF65_01974	ENOG4105PQ6	UPF0208 membrane protein
CF65_01976	ENOG4105E96	Colicin v production protein
CF65_01981	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CF65_01982	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CF65_01983	ENOG41061ZR	Transcriptional regulator
CF65_01985	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CF65_01986	ENOG4107QSN	dihydrolipoamide acetyltransferase
CF65_01988	ENOG4107QN2	dihydrolipoyl dehydrogenase
CF65_01991	ENOG41069NU	Nitroreductase
CF65_01992	ENOG4105D07	Signal peptide peptidase, SppA
CF65_01994	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CF65_01995	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CF65_01996	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CF65_01997	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CF65_01998	ENOG4105FE9	pseudouridine synthase
CF65_01999	ENOG4107R11	Transcriptional regulator
CF65_02000	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CF65_02001	ENOG4105XW2	UPF0263 protein
CF65_02003	ENOG4105ETE	Transcriptional regulator (LacI family
CF65_02004	ENOG4105DWV	Homoserine O-trans-acetylase
CF65_02005	ENOG4107GZ4	SanA protein
CF65_02006	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
CF65_02008	ENOG4107H6E	
CF65_02010	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CF65_02011	ENOG4107QIV	Cytochrome c biogenesis protein
CF65_02012	ENOG4105E0X	reductase
CF65_02013	ENOG41077A9	carbonic anhydrase
CF65_02014	ENOG4105W4M	Transport-associated protein
CF65_02015	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CF65_02017	ENOG41082RQ	UPF0102 protein
CF65_02018	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
CF65_02020	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CF65_02023	ENOG4105CEP	NADH dehydrogenase
CF65_02026	ENOG4105ERU	peptidase
CF65_02028	ENOG4105FGM	Fructosamine kinase
CF65_02030	ENOG4105C22	threonyL-tRNA synthetase
CF65_02034	ENOG4105DP0	ferredoxin-NADP reductase
CF65_02035	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CF65_02038	ENOG41082NX	50s ribosomal protein l35
CF65_02039	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CF65_02040	ENOG4108RS6	transposase
CF65_02042	ENOG4105D2M	Aldolase
CF65_02043	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CF65_02044	ENOG41082GB	PTS system galactitol-specific transporter subunit IIA
CF65_02045	ENOG41090UW	PTS System
CF65_02046	ENOG4105DT3	PTS system, galactitol-specific IIc component
CF65_02047	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
CF65_02048	ENOG4105E98	transcriptional regulator DeoR family
CF65_02050	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CF65_02051	ENOG4105CTB	Polyprenyl synthetase
CF65_02052	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CF65_02053	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CF65_02056	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CF65_02057	ENOG4108TGR	phosphatase
CF65_02060	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CF65_02062	ENOG4105DWU	Membrane
CF65_02063	ENOG4108W1A	pseudouridine synthase
CF65_02069	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
CF65_02077	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CF65_02081	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CF65_02084	ENOG4108ZZ3	UPF0260 protein
CF65_02087	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CF65_02088	ENOG4108ESZ	Glycogen debranching enzyme
CF65_02089	ENOG4108ESZ	Glycogen debranching enzyme
CF65_02092	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CF65_02094	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CF65_02097	ENOG4108VD1	dedA family
CF65_02099	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CF65_02101	ENOG41061WM	D-Alanyl-D-Alanine
CF65_02103	ENOG41061WM	D-Alanyl-D-Alanine
CF65_02105	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
CF65_02108	ENOG4105CEY	Amp-dependent synthetase and ligase
CF65_02111	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
CF65_02112	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
CF65_02113	ENOG4108TZV	Membrane
CF65_02114	ENOG4105CJB	Exodeoxyribonuclease I
CF65_02117	ENOG4105DQ6	Transposase
CF65_02120	ENOG41090A1	ferritin
CF65_02121	ENOG41090A1	ferritin
CF65_02124	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CF65_02125	ENOG4105Q9Y	Universal stress protein
CF65_02128	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CF65_02131	ENOG4105DB7	PHP domain protein
CF65_02132	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CF65_02134	ENOG4105CD8	aminopeptidase N
CF65_02136	ENOG4105CGF	Aromatic amino acid aminotransferase
CF65_02139	ENOG4105D0S	secretion protein (HlyD
CF65_02140	ENOG4105CJ1	ABC, transporter
CF65_02141	ENOG4105CMI	transporter
CF65_02144	ENOG4105EHG	Permease protein
CF65_02146	ENOG4105E0A	ABC, transporter
CF65_02150	ENOG4105HVQ	Regulatory factor of maltose metabolism
CF65_02151	ENOG4107RNH	Outer membrane receptor FepA
CF65_02152	ENOG4105E0A	ABC, transporter
CF65_02153	ENOG4105EHG	Permease protein
CF65_02154	ENOG4105S10	periplasmic binding protein
CF65_02156	ENOG4106ZKY	
CF65_02162	ENOG4108QBX	(LipO)protein
CF65_02163	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CF65_02164	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CF65_02166	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CF65_02168	ENOG4105D0M	Protease HtpX homolog
CF65_02171	ENOG4105C2X	Arabinose 5-phosphate isomerase
CF65_02172	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
CF65_02173	ENOG4105CRQ	synthase (Component I)
CF65_02175	ENOG4105DDQ	anthranilate synthase
CF65_02177	ENOG4108V5Q	transglutaminase-like protein
CF65_02179	ENOG4107QYG	anthranilate phosphoribosyltransferase
CF65_02181	ENOG41082AG	Plasmid maintenance system antidote protein
CF65_02182	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CF65_02184	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CF65_02193	ENOG4106AFN	Lyase and sodium transporter (By similarity)
CF65_02195	ENOG4107QSA	Oxaloacetate decarboxylase
CF65_02196	ENOG4105D9Q	decarboxylase (Beta subunit)
CF65_02201	ENOG4108MVK	Receptor
CF65_02202	ENOG4108MVK	Receptor
CF65_02205	ENOG4105EMU	Dehydrogenase
CF65_02206	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CF65_02210	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CF65_02214	ENOG4105CA9	Pyruvate kinase
CF65_02217	ENOG41061GT	Aldolase
CF65_02218	ENOG41061GT	Aldolase
CF65_02219	ENOG4105D4B	ABC, transporter
CF65_02224	ENOG41071MT	Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane
CF65_02226	ENOG4105C2J	ABC transporter
CF65_02228	ENOG4105DKT	Transcriptional regulator
CF65_02230	ENOG4107RYS	Autoinducer-2 (AI-2) kinase
CF65_02231	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CF65_02232	ENOG4105DAG	ROK family
CF65_02233	ENOG4105C5S	asparaginyl-tRNA synthetase
CF65_02235	ENOG4105KB2	stringent starvation protein b
CF65_02236	ENOG4107MKT	Stringent starvation protein a
CF65_02237	ENOG4108ZAF	Molybdopterin
CF65_02239	ENOG4105M00	molybdopterin converting factor, subunit 1
CF65_02242	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CF65_02243	ENOG4105CHW	UPF0052 protein
CF65_02246	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
CF65_02249	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CF65_02250	ENOG4105CUW	cytochrome C-TYPE protein
CF65_02251	ENOG4107QY8	reductase
CF65_02252	ENOG4105UNS	Pfam:DUF419
CF65_02254	ENOG4107QPK	)-transporter
CF65_02260	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CF65_02265	ENOG4107QYX	exodeoxyribonuclease v alpha
CF65_02266	ENOG4107QKA	exodeoxyribonuclease V beta
CF65_02267	ENOG41090EX	DsrE family
CF65_02269	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CF65_02270	ENOG4105DAN	ATP-dependent protease
CF65_02272	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
CF65_02273	ENOG4105VEQ	Cold shock protein
CF65_02275	ENOG4105X5C	UPF0181 protein
CF65_02276	ENOG4105DR9	pseudouridine synthase
CF65_02278	ENOG4105WP7	tRNA pseudouridine synthase C
CF65_02279	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
CF65_02280	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CF65_02281	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CF65_02282	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
CF65_02283	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CF65_02285	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
CF65_02286	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CF65_02288	ENOG4108BPE	-transporting atpase
CF65_02289	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CF65_02290	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CF65_02291	ENOG4105CIY	formyltetrahydrofolate deformylase
CF65_02292	ENOG4108SAU	DNA-binding protein H-ns
CF65_02294	ENOG4107S6Z	Na H antiporter
CF65_02300	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CF65_02301	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CF65_02303	ENOG4105CB5	ATP-dependent DNA helicase recG
CF65_02305	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CF65_02306	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CF65_02307	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CF65_02309	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CF65_02312	ENOG4108Z1B	Cyclase dehydrase
CF65_02313	ENOG4105VDB	UPF0125 protein
CF65_02315	ENOG4105EZE	Cupin 4 family protein
CF65_02317	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CF65_02319	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CF65_02320	ENOG4108IUZ	ABC transporter
CF65_02321	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CF65_02323	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
CF65_02324	ENOG4105DHJ	ABC, transporter
CF65_02325	ENOG4105CY3	ABC transporter, permease
CF65_02326	ENOG4107PE3	Mammalian cell entry related domain protein
CF65_02327	ENOG4105E3I	toluene tolerance
CF65_02329	ENOG4105VFK	BolA family
CF65_02330	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CF65_02332	ENOG4107R0E	Glycosyl transferase, family 2
CF65_02333	ENOG4105KZW	UPF0381 protein
CF65_02335	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CF65_02338	ENOG4105EE5	Membrane protein terC
CF65_02342	ENOG4105DQ6	Transposase
CF65_02343	ENOG4105C5F	glutamine synthetase
CF65_02344	ENOG4105CI3	gtp-binding protein typa
CF65_02348	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CF65_02349	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CF65_02350	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CF65_02351	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CF65_02352	ENOG4105E90	ABC transporter
CF65_02353	ENOG4108IJ8	ABC transporter
CF65_02354	ENOG4105DFA	alanine racemase domain protein
CF65_02357	ENOG4105CFH	Aspartokinase
CF65_02360	ENOG4105D98	threonine synthase
CF65_02363	ENOG4107QJR	hflk protein
CF65_02365	ENOG4105EPW	hflc protein
CF65_02367	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
CF65_02368	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CF65_02369	ENOG4105K8R	UPF0145 protein
CF65_02371	ENOG4105CSA	Coproporphyrinogen iii oxidase
CF65_02374	ENOG4105E66	phosphoriboisomerase A
CF65_02375	ENOG4108JQ1	Dehydrogenase
CF65_02380	ENOG4105S10	periplasmic binding protein
CF65_02381	ENOG4108UHU	Aldolase
CF65_02383	ENOG4105DMW	Dehydrogenase reductase
CF65_02384	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CF65_02385	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CF65_02387	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CF65_02389	ENOG4107YCY	Transcriptional regulator
CF65_02393	ENOG4105CHH	sulfate transporter
CF65_02395	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CF65_02397	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CF65_02398	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CF65_02399	ENOG4105VCC	30S ribosomal protein S21
CF65_02402	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CF65_02407	ENOG4107104	thymidine kinase
CF65_02410	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
CF65_02411	ENOG4105EXN	Sulfate transport protein CysZ
CF65_02412	ENOG4105C6T	cysteine synthase
CF65_02416	ENOG4108RG0	uracil-dna glycosylase
CF65_02417	ENOG4105C3G	gtp-binding protein
CF65_02418	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CF65_02420	ENOG4105DQ6	Transposase
CF65_02423	ENOG4105ESV	Glycosyl transferase, family 4
CF65_02425	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CF65_02426	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CF65_02429	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CF65_02430	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CF65_02432	ENOG4105BZ4	penicillin-binding protein
CF65_02434	ENOG4107SJW	iron permease, FTR1
CF65_02438	ENOG4107RBB	ABC transporter, permease
CF65_02440	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CF65_02442	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CF65_02446	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CF65_02454	ENOG4105CQ7	ATP-dependent helicase
CF65_02455	ENOG4105M08	Membrane
CF65_02456	ENOG4108VMM	UPF0756 membrane protein
CF65_02457	ENOG4105M2J	Glutaredoxin
CF65_02459	ENOG4105CQB	FAD linked oxidase domain protein
CF65_02460	ENOG4105KA0	thioesterase Superfamily protein
CF65_02462	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CF65_02463	ENOG4105CE4	GlcNAc 6-P deacetylase
CF65_02465	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CF65_02466	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CF65_02468	ENOG4105QEK	Transcriptional regulator
CF65_02472	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
CF65_02473	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
CF65_02474	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CF65_02476	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
CF65_02478	ENOG4105CI1	PTS System
CF65_02481	ENOG4105D7X	high-affinity nickel-transporter
CF65_02482	ENOG41065CD	Exported protein
CF65_02484	ENOG4105C5H	ABC transporter
CF65_02486	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CF65_02491	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CF65_02492	ENOG4108K3A	Glutathione S-transferase
CF65_02494	ENOG4108VTV	Inherit from NOG: Membrane
CF65_02495	ENOG4105M4H	endoribonuclease L-psp
CF65_02501	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CF65_02504	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CF65_02506	ENOG4105EJ9	Membrane
CF65_02507	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
CF65_02509	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CF65_02511	ENOG4105EGS	Mechanosensitive ion channel
CF65_02512	ENOG4105CEY	Amp-dependent synthetase and ligase
CF65_02513	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
CF65_02514	ENOG4105EV9	Alpha Beta Hydrolase
CF65_02515	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CF65_02516	ENOG41090R7	Ferric uptake
CF65_02519	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CF65_02523	ENOG4108ZJT	translation initiation factor, Sui1
CF65_02525	ENOG4105CFV	Tetratricopeptide repeat protein
CF65_02526	ENOG4105Q4A	inner membrane protein yciS
CF65_02527	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CF65_02528	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CF65_02529	ENOG4105CAT	Cytidine monophosphate kinase
CF65_02531	ENOG4108MJ5	VirK protein
CF65_02532	ENOG4105PE1	Receptor
CF65_02533	ENOG4107RAN	Peptidase, M16
CF65_02534	ENOG4107RAN	Peptidase, M16
CF65_02536	ENOG4105KMT	branched-chain amino acid
CF65_02538	ENOG4108UMN	azlc family
CF65_02539	ENOG4105DZ2	Transcriptional regulator
CF65_02540	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CF65_02543	ENOG4105DFS	Conserved Protein
CF65_02544	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CF65_02547	ENOG4108MN8	Membrane
CF65_02548	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CF65_02550	ENOG4105DIK	(ABC) transporter
CF65_02551	ENOG4105CC5	ABC transporter
CF65_02552	ENOG4105CC5	ABC transporter
CF65_02553	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CF65_02554	ENOG41068P6	UPF0319 protein
CF65_02556	ENOG4108Z5K	methylglyoxal synthase
CF65_02558	ENOG410901E	Membrane
CF65_02560	ENOG4105EM2	membrane
CF65_02561	ENOG4108DG9	Smr protein MutS2
CF65_02562	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CF65_02563	ENOG4108IUS	Transketolase
CF65_02565	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CF65_02573	ENOG4105C5H	ABC transporter
CF65_02574	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CF65_02575	ENOG41067MG	lrgb family
CF65_02576	ENOG4105VAW	lrga family
CF65_02577	ENOG4105KK6	nuclease
CF65_02579	ENOG4105C9B	Cysteine desulfurase
CF65_02581	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CF65_02584	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CF65_02586	ENOG4105D1S	lipid A biosynthesis
CF65_02587	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
CF65_02589	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
CF65_02591	ENOG4107QX8	SPFH domain, Band 7 family protein
CF65_02595	ENOG4105CA0	peroxidase
CF65_02597	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CF65_02598	ENOG4105CEY	Amp-dependent synthetase and ligase
CF65_02599	ENOG4105R8X	Outer membrane lipoprotein Slp
CF65_02600	ENOG41072GX	Peptidase M22 Glycoprotease
CF65_02601	ENOG4105DVT	helicase
CF65_02602	ENOG4105DSB	aldose 1-epimerase
CF65_02603	ENOG4107QR8	Thioredoxin
CF65_02604	ENOG4105C3M	thioredoxin reductase
CF65_02606	ENOG4108JJ9	ABC, transporter
CF65_02609	ENOG4108JJ8	(ABC) transporter
CF65_02610	ENOG4105C29	acyl-CoA thioesterase
CF65_02613	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
CF65_02615	ENOG4105F3T	(LipO)protein
CF65_02616	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CF65_02618	ENOG4105EYK	Phosphatidylglycerophosphatase B
CF65_02619	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CF65_02623	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CF65_02626	ENOG4105GXY	Family of unknown function (DUF695) 
CF65_02628	ENOG4105CGK	Exodeoxyribonuclease III
CF65_02631	ENOG4105D3Q	Sugar transferase
CF65_02632	ENOG4108KBE	Glycosyl transferase, family 2
CF65_02634	ENOG4108RT7	Glycosyl transferase, family 2
CF65_02636	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CF65_02640	ENOG4105K64	Glycosyl transferase, family 2
CF65_02643	ENOG4105MFV	ABC-2 type transporter
CF65_02644	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
CF65_02646	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
CF65_02647	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CF65_02648	ENOG4105CVE	Lytic murein transglycosylase
CF65_02649	ENOG4108RYC	glycosyltransferase
CF65_02651	ENOG4108RJ9	Glycosyl transferase, family 2
CF65_02654	ENOG41068D6	Glycosyltransferase
CF65_02656	ENOG4108ZPC	Polysaccharide pyruvyl transferase
CF65_02658	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
CF65_02659	ENOG41080C8	DUF218 domain
CF65_02666	ENOG4105C4R	Atp-dependent dna helicase
CF65_02668	ENOG4105C6Z	Gluconate
CF65_02671	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CF65_02673	ENOG4105DIQ	Transcriptional regulator
CF65_02674	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CF65_02677	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CF65_02678	ENOG4108MG3	formate dehydrogenase
CF65_02679	ENOG4108MG3	formate dehydrogenase
CF65_02682	ENOG4105C8H	hydrogenase maturation protein Hypf
CF65_02683	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
CF65_02684	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CF65_02686	ENOG4107TDF	Formate hydrogenlyase subunit 4
CF65_02687	ENOG4105D65	subunit l
CF65_02688	ENOG4107WQX	hydrogenase 4 membrane subunit
CF65_02689	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CF65_02692	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CF65_02695	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
CF65_02696	ENOG4105I6X	formate hydrogenlyase maturation
CF65_02697	ENOG4108MG9	hydrogenase 3 maturation protease
CF65_02698	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CF65_02699	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CF65_02700	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CF65_02702	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CF65_02704	ENOG4105C7S	Dehydrogenase
CF65_02706	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CF65_02708	ENOG4105C5X	domain protein
CF65_02710	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CF65_02711	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CF65_02712	ENOG4105CN1	protease
CF65_02713	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
CF65_02714	ENOG4105H2K	paraquat-inducible protein a
CF65_02715	ENOG4105DY2	Paraquat-inducible protein b
CF65_02716	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CF65_02718	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CF65_02719	ENOG4105F38	ABC transporter, permease
CF65_02720	ENOG4105D38	putrescine abc transporter
CF65_02721	ENOG4107RUE	extracellular solute-binding protein family 1
CF65_02722	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
CF65_02726	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CF65_02728	ENOG4105D1H	recombination factor protein RarA
CF65_02731	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CF65_02733	ENOG4105CNU	cell division protein FtsK
CF65_02734	ENOG4105EW9	transcriptional regulator AsnC family
CF65_02735	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CF65_02736	ENOG4105I7R	Adenylate cyclase
CF65_02737	ENOG4107IX6	phosphate transport regulator
CF65_02738	ENOG4105CJ3	phosphate transporter
CF65_02742	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CF65_02743	ENOG4108AD6	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
CF65_02745	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CF65_02747	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CF65_02751	ENOG4105DAA	L-lactate
CF65_02754	ENOG41090HJ	UPF0265 protein
CF65_02756	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CF65_02757	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CF65_02758	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CF65_02762	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CF65_02763	ENOG4107RZZ	dna polymerase iii epsilon subunit
CF65_02774	ENOG4105CFP	Peptidase U32
CF65_02775	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CF65_02776	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CF65_02779	ENOG4105VIE	preprotein translocase, subunit YajC
CF65_02780	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CF65_02781	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CF65_02782	ENOG4107ENK	receptor
CF65_02784	ENOG4108EKI	Dehydrogenase
CF65_02785	ENOG4105CNN	ABC, transporter
CF65_02786	ENOG4105C2J	ABC transporter
CF65_02787	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CF65_02789	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CF65_02790	ENOG4105C26	Dehydrogenase
CF65_02792	ENOG4105CXY	transporter
CF65_02793	ENOG4105ECY	inositol monophosphatase
CF65_02794	ENOG4105DH8	myo-inositol catabolism
CF65_02797	ENOG4105D7K	pfkb domain protein
CF65_02800	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CF65_02801	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CF65_02802	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
CF65_02803	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
CF65_02805	ENOG4108JJA	ABC, transporter
CF65_02806	ENOG4105DDI	hemolysin-type calcium-binding region
CF65_02810	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CF65_02818	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CF65_02819	ENOG4108WPU	DNA polymerase III subunit psi
CF65_02821	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
CF65_02823	ENOG4105DSY	exodeoxyribonuclease V, gamma
CF65_02829	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CF65_02830	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CF65_02836	ENOG4105E02	MotA TolQ exbB proton channel
CF65_02837	ENOG4107YD3	Thioesterase
CF65_02840	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CF65_02841	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CF65_02844	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CF65_02848	ENOG4105CDY	transcriptional regulatory protein
CF65_02850	ENOG4108TIT	dATP pyrophosphohydrolase
CF65_02853	ENOG4105K3M	)-transporter
CF65_02856	ENOG4105C9M	aspartyl-trna synthetase
CF65_02857	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
CF65_02864	ENOG4105CXY	transporter
CF65_02865	ENOG4107ENK	receptor
CF65_02866	ENOG4108UYE	Lactoylglutathione lyase
CF65_02867	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CF65_02870	ENOG4105D3Y	Na H antiporter
CF65_02873	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CF65_02875	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CF65_02878	ENOG4105WPN	DNA integration recombination invertion protein
CF65_02879	ENOG4105EAH	synthase
CF65_02883	ENOG4105QYV	Membrane
CF65_02885	ENOG4105QYV	Membrane
CF65_02886	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CF65_02888	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CF65_02891	ENOG4108J59	Extracellular solute-binding protein, family 5
CF65_02892	ENOG4108J59	Extracellular solute-binding protein, family 5
CF65_02893	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CF65_02895	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CF65_02897	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CF65_02898	ENOG4105C3U	ABC transporter
CF65_02899	ENOG4108JQ7	(ABC) transporter
CF65_02902	ENOG41065U4	response regulator
CF65_02903	ENOG4105YK5	50S ribosomal protein L36
CF65_02904	ENOG4105NRA	50s ribosomal protein l31 type b
CF65_02905	ENOG4108URH	decarboxylase
CF65_02909	ENOG4105MGM	doxx family
CF65_02910	ENOG4105C03	ribonuclease
CF65_02913	ENOG4105EI2	Pseudouridine synthase
CF65_02915	ENOG4105K63	Thioredoxin
CF65_02916	ENOG4105C5I	Dehydrogenase
CF65_02917	ENOG4105C28	cystathionine
CF65_02919	ENOG4105EJX	conjugal transfer ATPase
CF65_02921	ENOG4105MZU	cell filamentation protein
CF65_02922	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CF65_02925	ENOG4105EN6	Membrane
CF65_02930	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CF65_02931	ENOG4105DFU	Cell wall formation (By similarity)
CF65_02932	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CF65_02933	ENOG4105CUZ	uba thif-type nad fad binding protein
CF65_02935	ENOG4105NXV	High-affinity zinc uptake system protein
CF65_02936	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
CF65_02937	ENOG4108VPT	UPF0234 protein
CF65_02939	ENOG4105EAC	phosphoserine phosphatase
CF65_02940	ENOG41062Z9	Membrane
CF65_02946	ENOG4105CJR	Integral membrane protein (MviN
CF65_02947	ENOG4105DTN	riboflavin biosynthesis protein ribF
CF65_02952	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CF65_02955	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CF65_02956	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CF65_02958	ENOG4105D8G	Major Facilitator superfamily
CF65_02959	ENOG4105II7	pyrroline-5-carboxylate reductase
CF65_02961	ENOG4105II7	pyrroline-5-carboxylate reductase
CF65_02962	ENOG4105DH7	May be involved in recombination (By similarity)
CF65_02964	ENOG4108UBT	opacity-associated protein
CF65_02966	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CF65_02970	ENOG4105C0F	tryptophanase EC 4.1.99.1
CF65_02973	ENOG4105E0U	tyrosine-specific transport protein
CF65_02974	ENOG4105WWK	YheO domain protein
CF65_02976	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CF65_02977	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CF65_02978	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
CF65_02982	ENOG4105F1A	Pyruvate formate-lyase
CF65_02983	ENOG4105C6N	Formate acetyltransferase
CF65_02984	ENOG4105TMB	Formate nitrite transporter
CF65_02987	ENOG4105K59	histidine triad (HIT) protein
CF65_02990	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CF65_02993	ENOG4105CTQ	phosphohexokinase
CF65_02996	ENOG41076HS	cation diffusion facilitator family transporter
CF65_02999	ENOG4105D1Q	UPF0246 protein
CF65_03000	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CF65_03001	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
CF65_03003	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CF65_03004	ENOG4105C3F	Signal peptidase i
CF65_03010	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CF65_03011	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CF65_03013	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CF65_03014	ENOG4105VG0	50S ribosomal protein l34