locus-tag	class	description
FXN58_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FXN58_00010	COG0592	DNA-directed DNA polymerase activity
FXN58_00020	COG2226	methyltransferase
FXN58_00035	COG0281	malic enzyme
FXN58_00040	COG2081	HI0933 family
FXN58_00045	COG4235	cytochrome complex assembly
FXN58_00045	COG3088	subunit of a heme lyase
FXN58_00050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FXN58_00055	COG1138	Cytochrome C-type biogenesis protein
FXN58_00065	COG3301	Polysulphide reductase, NrfD
FXN58_00070	COG0437	4 iron, 4 sulfur cluster binding
FXN58_00075	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FXN58_00110	COG1138	Cytochrome C-type biogenesis protein
FXN58_00120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FXN58_00125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FXN58_00130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FXN58_00135	COG4133	protoheme IX ABC transporter activity
FXN58_00180	COG2267	carboxylic ester hydrolase activity
FXN58_00185	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FXN58_00195	COG0436	Aminotransferase
FXN58_00210	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FXN58_00215	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FXN58_00220	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FXN58_00230	COG1652	LysM domain
FXN58_00235	COG2321	neutral zinc metallopeptidase
FXN58_00245	COG3293	Transposase
FXN58_00255	COG0281	malic enzyme
FXN58_00255	COG0280	phosphate acetyltransferase
FXN58_00335	COG3293	Transposase
FXN58_00345	COG2801	Transposase and inactivated derivatives
FXN58_00350	COG3091	SprT-like family
FXN58_00355	COG0814	amino acid
FXN58_00360	COG1760	l-serine dehydratase
FXN58_00365	COG0252	asparaginase activity
FXN58_00375	COG3063	Type IV pilus biogenesis stability protein PilW
FXN58_00380	COG1426	Protein conserved in bacteria
FXN58_00395	COG2976	Protein conserved in bacteria
FXN58_00405	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FXN58_00410	COG2233	PERMEase
FXN58_00415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FXN58_00420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FXN58_00425	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FXN58_00435	COG0659	secondary active sulfate transmembrane transporter activity
FXN58_00455	COG2186	Transcriptional regulator
FXN58_00470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FXN58_00480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FXN58_00495	COG0800	Aldolase
FXN58_00510	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FXN58_00515	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FXN58_00525	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FXN58_00530	COG1555	photosystem II stabilization
FXN58_00540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FXN58_00560	COG0196	riboflavin kinase activity
FXN58_00565	COG0728	peptidoglycan biosynthetic process
FXN58_00580	COG0560	Phosphoserine phosphatase
FXN58_00590	COG0193	aminoacyl-tRNA hydrolase activity
FXN58_00595	COG0012	GTP binding
FXN58_00605	COG1573	uracil-dna glycosylase
FXN58_00610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FXN58_00620	COG3115	cell septum assembly
FXN58_00640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FXN58_00645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FXN58_00655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FXN58_00680	COG2801	Transposase and inactivated derivatives
FXN58_00725	COG3161	chorismate lyase activity
FXN58_00735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FXN58_00740	COG1758	RNA polymerase activity
FXN58_00750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FXN58_00785	COG2801	Transposase and inactivated derivatives
FXN58_00790	COG3293	Transposase
FXN58_00810	COG2271	Major facilitator Superfamily
FXN58_00820	COG1215	transferase activity, transferring glycosyl groups
FXN58_00825	COG0726	polysaccharide deacetylase
FXN58_00825	COG1649	PFAM Uncharacterised BCR, COG1649
FXN58_00840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FXN58_00845	COG0561	phosphatase activity
FXN58_00850	COG3716	PTS system mannose fructose sorbose family IID component
FXN58_00860	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_00860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN58_00865	COG0742	ribosomal rna small subunit methyltransferase
FXN58_00870	COG0552	protein localization to endoplasmic reticulum
FXN58_00875	COG2884	Cell division ATP-binding protein ftsE
FXN58_00880	COG2177	Part of the ABC transporter FtsEX involved in
FXN58_00910	COG1575	Belongs to the MenA family. Type 1 subfamily
FXN58_00920	COG3293	Transposase
FXN58_00930	COG3028	Belongs to the UPF0307 family
FXN58_00935	COG0312	modulator of DNA gyrase
FXN58_00940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FXN58_00945	COG1929	Belongs to the glycerate kinase type-1 family
FXN58_00960	COG2801	Transposase and inactivated derivatives
FXN58_00970	COG0513	Belongs to the DEAD box helicase family
FXN58_00975	COG4785	May be involved in cell division
FXN58_00985	COG2731	YhcH YjgK YiaL family protein
FXN58_00990	COG3023	N-Acetylmuramoyl-L-alanine amidase
FXN58_00995	COG4969	Belongs to the N-Me-Phe pilin family
FXN58_01040	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FXN58_01060	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FXN58_01065	COG0222	ribosome binding
FXN58_01080	COG2932	Transcriptional regulator
FXN58_01100	COG0789	Transcriptional regulator
FXN58_01105	COG2608	mercury ion transmembrane transporter activity
FXN58_01110	COG2217	Heavy metal translocating P-type atpase
FXN58_01135	COG0740	serine-type endopeptidase activity
FXN58_01140	COG2194	sulfuric ester hydrolase activity
FXN58_01145	COG2918	glutathione biosynthetic process
FXN58_01145	COG1181	Belongs to the D-alanine--D-alanine ligase family
FXN58_01170	COG2801	Transposase and inactivated derivatives
FXN58_01190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FXN58_01190	COG0237	dephospho-CoA kinase activity
FXN58_01195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FXN58_01205	COG1115	amino acid carrier protein
FXN58_01210	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FXN58_01245	COG4145	pantothenate transmembrane transporter activity
FXN58_01250	COG3924	membrane
FXN58_01265	COG3293	Transposase
FXN58_01270	COG0439	Biotin carboxylase
FXN58_01275	COG0511	ligase activity, forming carbon-carbon bonds
FXN58_01300	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FXN58_01310	COG0456	acetyltransferase
FXN58_01315	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FXN58_01325	COG3078	GTPase activator activity
FXN58_01330	COG3293	Transposase
FXN58_01335	COG3501	Rhs element vgr protein
FXN58_01345	COG3201	nicotinamide mononucleotide transporter
FXN58_01355	COG0513	Belongs to the DEAD box helicase family
FXN58_01390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FXN58_01400	COG0251	oxidation-reduction process
FXN58_01405	COG2137	regulation of response to DNA damage stimulus
FXN58_01410	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FXN58_01465	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FXN58_01495	COG1238	metal cluster binding
FXN58_01500	COG0110	maltose O-acetyltransferase activity
FXN58_01505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FXN58_01525	COG0210	DNA helicase
FXN58_01530	COG5645	(Lipo)protein
FXN58_01540	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FXN58_01540	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FXN58_01550	COG3293	Transposase
FXN58_01555	COG0243	molybdopterin cofactor binding
FXN58_01570	COG3293	Transposase
FXN58_01575	COG3381	protein complex oligomerization
FXN58_01580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FXN58_01580	COG2221	Nitrite and sulphite reductase 4Fe-4S
FXN58_01590	COG4545	Glutaredoxin-related protein
FXN58_01605	COG3293	Transposase
FXN58_01625	COG1114	Component of the transport system for branched-chain amino acids
FXN58_01635	COG3293	Transposase
FXN58_01640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FXN58_01640	COG0140	phosphoribosyl-ATP diphosphatase activity
FXN58_01655	COG0561	phosphatase activity
FXN58_01660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FXN58_01665	COG1596	polysaccharide export
FXN58_01665	COG1555	photosystem II stabilization
FXN58_01685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FXN58_01690	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FXN58_01725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FXN58_01780	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FXN58_01790	COG1028	Short-chain dehydrogenase reductase Sdr
FXN58_01795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FXN58_01820	COG0737	Belongs to the 5'-nucleotidase family
FXN58_01830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FXN58_01840	COG0859	PFAM glycosyl transferase family 9
FXN58_01845	COG0754	glutathionylspermidine amidase activity
FXN58_01850	COG3005	denitrification pathway
FXN58_01855	COG3043	anaerobic respiration
FXN58_01860	COG0348	domain, Protein
FXN58_01865	COG0437	4 iron, 4 sulfur cluster binding
FXN58_01870	COG0243	molybdopterin cofactor binding
FXN58_01875	COG3062	negative regulation of establishment of protein localization
FXN58_01880	COG3850	Histidine kinase
FXN58_01885	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FXN58_01895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FXN58_01910	COG0582	viral genome integration into host DNA
FXN58_01920	COG1070	Carbohydrate kinase
FXN58_01925	COG2115	Belongs to the xylose isomerase family
FXN58_01930	COG4213	ABC transporter substrate-binding protein
FXN58_01935	COG1129	ABC transporter
FXN58_01940	COG4214	carbohydrate transport
FXN58_01945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FXN58_01950	COG1757	Na H antiporter
FXN58_01955	COG1609	Transcriptional regulator
FXN58_01955	COG2207	Transcriptional regulator
FXN58_01965	COG0297	glycogen (starch) synthase activity
FXN58_01975	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FXN58_01985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FXN58_02005	COG0662	Cupin 2, conserved barrel domain protein
FXN58_02005	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FXN58_02010	COG2814	Major facilitator Superfamily
FXN58_02015	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN58_02015	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_02020	COG3715	PTS system
FXN58_02025	COG3716	PTS system mannose fructose sorbose family IID component
FXN58_02040	COG0859	PFAM glycosyl transferase family 9
FXN58_02045	COG1027	Aspartate ammonia-lyase
FXN58_02055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FXN58_02060	COG0459	protein refolding
FXN58_02090	COG3293	Transposase
FXN58_02100	COG3293	Transposase
FXN58_02105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FXN58_02115	COG0688	phosphatidylethanolamine metabolic process
FXN58_02130	COG2830	Protein of unknown function (DUF452)
FXN58_02145	COG1399	metal-binding, possibly nucleic acid-binding protein
FXN58_02150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FXN58_02155	COG0416	fatty acid biosynthetic process
FXN58_02165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FXN58_02170	COG1028	Short-chain dehydrogenase reductase Sdr
FXN58_02180	COG2814	Major facilitator Superfamily
FXN58_02185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FXN58_02190	COG0513	Belongs to the DEAD box helicase family
FXN58_02195	COG0799	negative regulation of ribosome biogenesis
FXN58_02205	COG0768	penicillin binding
FXN58_02210	COG0772	Belongs to the SEDS family
FXN58_02215	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FXN58_02215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FXN58_02220	COG1686	Belongs to the peptidase S11 family
FXN58_02250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FXN58_02255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FXN58_02260	COG0765	amino acid transport
FXN58_02265	COG1126	abc transporter atp-binding protein
FXN58_02270	COG2168	tRNA wobble position uridine thiolation
FXN58_02280	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FXN58_02285	COG2964	Protein conserved in bacteria
FXN58_02290	COG0545	Peptidyl-prolyl cis-trans isomerase
FXN58_02295	COG2900	Belongs to the SlyX family
FXN58_02300	COG0678	peroxiredoxin activity
FXN58_02300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FXN58_02305	COG0583	DNA-binding transcription factor activity
FXN58_02310	COG1309	transcriptional regulator
FXN58_02315	COG1132	(ABC) transporter
FXN58_02320	COG4988	ABC transporter
FXN58_02325	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FXN58_02330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FXN58_02335	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FXN58_02345	COG1045	serine acetyltransferase
FXN58_02355	COG1494	fructose-1,6-bisphosphatase
FXN58_02365	COG0716	FMN binding
FXN58_02380	COG1733	regulation of RNA biosynthetic process
FXN58_02390	COG3312	ion transport
FXN58_02410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FXN58_02420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FXN58_02435	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FXN58_02440	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FXN58_02450	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FXN58_02470	COG3293	Transposase
FXN58_02500	COG3293	Transposase
FXN58_02505	COG4783	chaperone-mediated protein folding
FXN58_02515	COG0814	amino acid
FXN58_02550	COG0747	negative chemotaxis
FXN58_02555	COG2853	Lipoprotein
FXN58_02625	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FXN58_02630	COG3610	response to peptide
FXN58_02635	COG2966	Psort location CytoplasmicMembrane, score
FXN58_02640	COG3293	Transposase
FXN58_02650	COG0848	biopolymer transport protein
FXN58_02655	COG0811	peptide transport
FXN58_02660	COG4536	flavin adenine dinucleotide binding
FXN58_02665	COG4137	Cytochrome C assembly protein
FXN58_02670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FXN58_02685	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FXN58_02690	COG0789	Transcriptional regulator
FXN58_02695	COG4221	oxidoreductase activity
FXN58_02705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FXN58_02725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FXN58_02730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FXN58_02735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FXN58_02740	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FXN58_02745	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FXN58_02760	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FXN58_02765	COG1466	dna polymerase III delta subunit
FXN58_02770	COG0494	nUDIX hydrolase
FXN58_02785	COG4701	Protein of unknown function (DUF721)
FXN58_02790	COG0789	Transcriptional regulator
FXN58_02795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FXN58_02815	COG3293	Transposase
FXN58_02830	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FXN58_02845	COG4796	Type ii and iii secretion system protein
FXN58_02865	COG4972	Pilus assembly protein
FXN58_02870	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FXN58_02875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FXN58_02880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FXN58_02895	COG1309	transcriptional regulator
FXN58_02905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FXN58_02920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FXN58_02940	COG3306	glycosyltransferase involved in LPS biosynthesis
FXN58_02950	COG3306	glycosyltransferase involved in LPS biosynthesis
FXN58_02965	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FXN58_02975	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FXN58_02980	COG1309	transcriptional regulator
FXN58_02985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FXN58_02990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FXN58_03005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FXN58_03010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FXN58_03015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FXN58_03020	COG1381	Involved in DNA repair and RecF pathway recombination
FXN58_03025	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FXN58_03045	COG0354	folic acid binding
FXN58_03050	COG1561	YicC-like family, N-terminal region
FXN58_03060	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FXN58_03075	COG3842	ATPase activity
FXN58_03080	COG1178	ABC-type Fe3 transport system permease component
FXN58_03085	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN58_03090	COG3171	Protein conserved in bacteria
FXN58_03100	COG1194	a g-specific adenine glycosylase
FXN58_03105	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FXN58_03125	COG3056	Lipoprotein
FXN58_03130	COG0271	Belongs to the BolA IbaG family
FXN58_03145	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FXN58_03150	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FXN58_03155	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FXN58_03160	COG2871	sodium ion transport
FXN58_03165	COG1477	protein flavinylation
FXN58_03170	COG2991	Protein conserved in bacteria
FXN58_03185	COG0148	phosphopyruvate hydratase activity
FXN58_03200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FXN58_03205	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FXN58_03210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FXN58_03220	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FXN58_03235	COG3956	TIGRFAM MazG family protein
FXN58_03240	COG0402	S-adenosylhomocysteine deaminase activity
FXN58_03245	COG3083	sulfuric ester hydrolase activity
FXN58_03250	COG3082	Protein of unknown function (DUF1414)
FXN58_03260	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FXN58_03265	COG0745	RESPONSE REGULATOR receiver
FXN58_03270	COG2205	protein histidine kinase activity
FXN58_03275	COG0786	glutamate:sodium symporter activity
FXN58_03295	COG2258	MOSC domain
FXN58_03310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FXN58_03315	COG1349	DNA-binding transcription factor activity
FXN58_03325	COG3068	Protein conserved in bacteria
FXN58_03330	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FXN58_03350	COG0248	Ppx GppA phosphatase
FXN58_03355	COG2911	Protein conserved in bacteria
FXN58_03360	COG0729	surface antigen
FXN58_03365	COG2197	response regulator
FXN58_03375	COG0181	hydroxymethylbilane synthase activity
FXN58_03385	COG2959	enzyme of heme biosynthesis
FXN58_03390	COG3071	HemY protein
FXN58_03395	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FXN58_03405	COG1595	DNA-templated transcription, initiation
FXN58_03415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FXN58_03420	COG2183	response to ionizing radiation
FXN58_03430	COG0471	metal ion transport
FXN58_03435	COG0583	DNA-binding transcription factor activity
FXN58_03440	COG2183	response to ionizing radiation
FXN58_03445	COG3293	Transposase
FXN58_03455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FXN58_03460	COG1129	ABC transporter
FXN58_03465	COG1879	ABC-type sugar transport system periplasmic component
FXN58_03470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FXN58_03485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FXN58_03495	COG0583	DNA-binding transcription factor activity
FXN58_03500	COG2962	Rard protein
FXN58_03515	COG0551	DNA topoisomerase type I activity
FXN58_03540	COG0705	Rhomboid family
FXN58_03545	COG1349	DNA-binding transcription factor activity
FXN58_03560	COG4178	(ABC) transporter
FXN58_03575	COG0233	cytoplasmic translational termination
FXN58_03590	COG0575	Belongs to the CDS family
FXN58_03605	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FXN58_03615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FXN58_03625	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FXN58_03635	COG0471	metal ion transport
FXN58_03635	COG0490	domain, Protein
FXN58_03640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FXN58_03650	COG4589	Belongs to the CDS family
FXN58_03655	COG0521	Mo-molybdopterin cofactor biosynthetic process
FXN58_03675	COG3276	selenocysteine insertion sequence binding
FXN58_03680	COG1921	L-seryl-tRNASec selenium transferase activity
FXN58_03685	COG0442	prolyl-tRNA aminoacylation
FXN58_03700	COG1595	DNA-templated transcription, initiation
FXN58_03705	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FXN58_03710	COG3026	antisigma factor binding
FXN58_03715	COG3086	response to oxidative stress
FXN58_03720	COG1763	Mo-molybdopterin cofactor biosynthetic process
FXN58_03725	COG0300	oxidoreductase activity
FXN58_03730	COG2195	Cleaves the N-terminal amino acid of tripeptides
FXN58_03740	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FXN58_03745	COG2818	Glycosylase
FXN58_03750	COG3477	response to acidic pH
FXN58_03755	COG0019	diaminopimelate decarboxylase activity
FXN58_03770	COG0514	ATP-dependent DNA helicase (RecQ)
FXN58_03775	COG0187	DNA topoisomerase II activity
FXN58_03780	COG1072	(Pantothenic acid kinase))
FXN58_03805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FXN58_03820	COG0561	phosphatase activity
FXN58_03825	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FXN58_03830	COG2267	carboxylic ester hydrolase activity
FXN58_03835	COG3307	-O-antigen
FXN58_03840	COG0191	fructose-bisphosphate aldolase activity
FXN58_03850	COG3719	Belongs to the RNase T2 family
FXN58_03855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FXN58_03860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FXN58_03865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FXN58_03880	COG0463	Glycosyl transferase, family 2
FXN58_03885	COG1519	Transferase
FXN58_03900	COG0859	PFAM glycosyl transferase family 9
FXN58_03905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FXN58_03910	COG1917	Cupin 2, conserved barrel domain protein
FXN58_03910	COG4977	sequence-specific DNA binding
FXN58_03915	COG1132	(ABC) transporter
FXN58_03950	COG0758	DNA mediated transformation
FXN58_03955	COG0584	glycerophosphoryl diester phosphodiesterase
FXN58_03960	COG2271	Major facilitator Superfamily
FXN58_03970	COG0557	exoribonuclease II activity
FXN58_03975	COG1077	Cell shape determining protein MreB Mrl
FXN58_03980	COG1792	Involved in formation and maintenance of cell shape
FXN58_03985	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FXN58_04015	COG0006	proline dipeptidase activity
FXN58_04035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FXN58_04060	COG0778	Nitroreductase
FXN58_04070	COG0762	integral membrane protein
FXN58_04090	COG0363	glucosamine-6-phosphate deaminase activity
FXN58_04095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FXN58_04100	COG1218	3'(2'),5'-bisphosphate nucleotidase
FXN58_04110	COG1297	OPT oligopeptide transporter protein
FXN58_04115	COG3293	Transposase
FXN58_04120	COG3059	membrane
FXN58_04125	COG1917	Cupin 2, conserved barrel domain protein
FXN58_04125	COG4977	sequence-specific DNA binding
FXN58_04130	COG0494	nUDIX hydrolase
FXN58_04135	COG1011	Hydrolase
FXN58_04140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FXN58_04145	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FXN58_04150	COG3293	Transposase
FXN58_04170	COG3293	Transposase
FXN58_04180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FXN58_04185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FXN58_04190	COG0805	protein transport
FXN58_04205	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FXN58_04215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FXN58_04225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FXN58_04235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FXN58_04245	COG1841	ribosomal large subunit assembly
FXN58_04255	COG0201	protein transport
FXN58_04275	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FXN58_04290	COG0814	amino acid
FXN58_04300	COG3423	Transcriptional regulator
FXN58_04315	COG2129	metallophosphoesterase
FXN58_04320	COG3172	ATPase kinase involved in NAD metabolism
FXN58_04335	COG1739	Uncharacterized protein family UPF0029
FXN58_04345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FXN58_04350	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FXN58_04395	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FXN58_04400	COG0084	hydrolase, TatD family'
FXN58_04405	COG0602	queuosine metabolic process
FXN58_04410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FXN58_04410	COG1328	CTP reductase activity
FXN58_04420	COG1022	Amp-dependent synthetase and ligase
FXN58_04425	COG0587	DNA-directed DNA polymerase activity
FXN58_04440	COG0753	catalase activity
FXN58_04445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FXN58_04450	COG0165	Argininosuccinate lyase
FXN58_04480	COG0582	viral genome integration into host DNA
FXN58_04515	COG1598	PFAM Uncharacterised protein family UPF0150
FXN58_04530	COG3617	BRO family, N-terminal domain
FXN58_04545	COG1869	D-ribose catabolic process
FXN58_04555	COG0730	response to heat
FXN58_04565	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FXN58_04575	COG0590	tRNA wobble adenosine to inosine editing
FXN58_04605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FXN58_04610	COG4942	peptidase
FXN58_04615	COG2861	carbohydrate metabolic process
FXN58_04620	COG0606	chelatase, subunit chli
FXN58_04675	COG3293	Transposase
FXN58_04715	COG3501	Rhs element vgr protein
FXN58_04730	COG3293	Transposase
FXN58_04745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FXN58_04775	COG2990	Protein conserved in bacteria
FXN58_04780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FXN58_04800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FXN58_04840	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FXN58_04840	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FXN58_04845	COG0569	domain protein
FXN58_04855	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FXN58_04870	COG2841	Protein conserved in bacteria
FXN58_04875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FXN58_04880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FXN58_04885	COG3036	rescue of stalled ribosome
FXN58_04895	COG1393	Belongs to the ArsC family
FXN58_04905	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FXN58_04910	COG1522	sequence-specific DNA binding
FXN58_04920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FXN58_04925	COG0038	chloride channel
FXN58_04930	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FXN58_04935	COG0549	Belongs to the carbamate kinase family
FXN58_04940	COG1288	antiporter activity
FXN58_04950	COG0183	Belongs to the thiolase family
FXN58_04955	COG2031	fatty acid transporter
FXN58_04960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FXN58_04965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FXN58_04970	COG3293	Transposase
FXN58_04980	COG0051	transcription antitermination factor activity, RNA binding
FXN58_04985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FXN58_04990	COG0088	Forms part of the polypeptide exit tunnel
FXN58_04995	COG0089	rRNA binding
FXN58_05000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FXN58_05005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FXN58_05010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FXN58_05015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FXN58_05020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FXN58_05025	COG0255	Belongs to the universal ribosomal protein uL29 family
FXN58_05030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FXN58_05045	COG2801	Transposase and inactivated derivatives
FXN58_05105	COG4964	Belongs to the GSP D family
FXN58_05135	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FXN58_05145	COG1444	tRNA N-acetyltransferase activity
FXN58_05150	COG3293	Transposase
FXN58_05155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FXN58_05165	COG1126	abc transporter atp-binding protein
FXN58_05170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FXN58_05175	COG4215	(ABC) transporter
FXN58_05180	COG4160	amino acid transport
FXN58_05185	COG1966	Carbon starvation protein
FXN58_05200	COG3116	cell division
FXN58_05205	COG0768	penicillin binding
FXN58_05215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FXN58_05225	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FXN58_05235	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FXN58_05250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FXN58_05255	COG0849	cell division
FXN58_05260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FXN58_05270	COG0077	Prephenate dehydratase
FXN58_05270	COG1605	Chorismate mutase
FXN58_05275	COG0326	Molecular chaperone. Has ATPase activity
FXN58_05280	COG1393	Belongs to the ArsC family
FXN58_05290	COG1876	peptidase activity
FXN58_05295	COG0494	nUDIX hydrolase
FXN58_05300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FXN58_05345	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FXN58_05355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FXN58_05360	COG1053	succinate dehydrogenase
FXN58_05375	COG1120	ATPase activity
FXN58_05380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FXN58_05390	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FXN58_05405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FXN58_05410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FXN58_05440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FXN58_05450	COG0741	lytic transglycosylase activity
FXN58_05455	COG2350	Protein conserved in bacteria
FXN58_05460	COG1607	acyl-coa hydrolase
FXN58_05465	COG2917	probably involved in intracellular septation
FXN58_05475	COG3293	Transposase
FXN58_05480	COG3047	cAMP biosynthetic process
FXN58_05485	COG0497	DNA recombination
FXN58_05495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FXN58_05505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FXN58_05505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FXN58_05510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FXN58_05515	COG2198	Histidine kinase
FXN58_05515	COG5002	protein histidine kinase activity
FXN58_05515	COG0784	Response regulator, receiver
FXN58_05520	COG3293	Transposase
FXN58_05525	COG4211	Belongs to the binding-protein-dependent transport system permease family
FXN58_05535	COG1879	ABC-type sugar transport system periplasmic component
FXN58_05540	COG1609	Transcriptional regulator
FXN58_05545	COG1085	galactose-1-phosphate uridylyltransferase
FXN58_05550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FXN58_05555	COG2017	converts alpha-aldose to the beta-anomer
FXN58_05585	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FXN58_05590	COG4535	Mg2 and Co2 transporter CorC
FXN58_05610	COG0105	UTP biosynthetic process
FXN58_05630	COG1388	LysM domain
FXN58_05630	COG4942	peptidase
FXN58_05640	COG1238	metal cluster binding
FXN58_05670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FXN58_05685	COG3293	Transposase
FXN58_05700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FXN58_05710	COG0733	neurotransmitter:sodium symporter activity
FXN58_05720	COG1285	pathogenesis
FXN58_05725	COG2801	Transposase and inactivated derivatives
FXN58_05765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FXN58_05765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FXN58_05765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FXN58_05770	COG1105	Belongs to the carbohydrate kinase PfkB family
FXN58_05775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_05775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_05785	COG0746	molybdenum cofactor guanylyltransferase activity
FXN58_05790	COG3084	Protein conserved in bacteria
FXN58_05795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FXN58_05800	COG3085	chromosome segregation
FXN58_05855	COG0561	phosphatase activity
FXN58_05865	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FXN58_05875	COG2610	gluconate transmembrane transporter activity
FXN58_05885	COG0235	Class ii aldolase
FXN58_05890	COG3395	kinase activity
FXN58_05895	COG2084	Dehydrogenase
FXN58_05900	COG1349	DNA-binding transcription factor activity
FXN58_05905	COG0347	Belongs to the P(II) protein family
FXN58_05910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FXN58_05915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FXN58_05920	COG0470	DNA polymerase III
FXN58_05925	COG0084	hydrolase, TatD family'
FXN58_05935	COG1253	flavin adenine dinucleotide binding
FXN58_05940	COG3293	Transposase
FXN58_05965	COG0489	protein tyrosine kinase activity
FXN58_05970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FXN58_05970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FXN58_05975	COG2975	iron-sulfur cluster assembly
FXN58_05980	COG0633	Ferredoxin
FXN58_05985	COG0443	Heat shock 70 kDa protein
FXN58_06000	COG3293	Transposase
FXN58_06005	COG0822	iron-sulfur transferase activity
FXN58_06015	COG1959	2 iron, 2 sulfur cluster binding
FXN58_06020	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FXN58_06060	COG0626	cystathionine gamma-synthase activity
FXN58_06065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FXN58_06085	COG1530	ribonuclease E activity
FXN58_06095	COG2259	Doxx family
FXN58_06100	COG3293	Transposase
FXN58_06110	COG1611	Belongs to the LOG family
FXN58_06120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FXN58_06125	COG0745	RESPONSE REGULATOR receiver
FXN58_06130	COG4608	Belongs to the ABC transporter superfamily
FXN58_06135	COG0444	Belongs to the ABC transporter superfamily
FXN58_06140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FXN58_06145	COG0601	transmembrane transport
FXN58_06150	COG4166	transmembrane transport
FXN58_06160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FXN58_06165	COG0697	spore germination
FXN58_06185	COG0142	geranyltranstransferase activity
FXN58_06190	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FXN58_06215	COG2056	Na+-H+ antiporter family
FXN58_06220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FXN58_06225	COG0346	lactoylglutathione lyase activity
FXN58_06235	COG2271	Major facilitator Superfamily
FXN58_06250	COG1755	Isoprenylcysteine carboxyl methyltransferase
FXN58_06255	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FXN58_06265	COG3293	Transposase
FXN58_06275	COG0494	nUDIX hydrolase
FXN58_06280	COG0217	transcriptional regulatory protein
FXN58_06310	COG1271	oxidase subunit
FXN58_06315	COG1294	oxidase, subunit
FXN58_06330	COG0824	Thioesterase
FXN58_06335	COG0811	peptide transport
FXN58_06340	COG0848	biopolymer transport protein
FXN58_06345	COG3064	Membrane
FXN58_06370	COG4795	General secretion pathway protein
FXN58_06385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FXN58_06390	COG0456	acetyltransferase
FXN58_06395	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FXN58_06400	COG2813	Specifically methylates the guanine in position
FXN58_06420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FXN58_06430	COG2994	toxin metabolic process
FXN58_06435	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FXN58_06440	COG2274	protein secretion by the type I secretion system
FXN58_06445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FXN58_06450	COG0673	inositol 2-dehydrogenase activity
FXN58_06460	COG3962	Belongs to the TPP enzyme family
FXN58_06465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FXN58_06480	COG3293	Transposase
FXN58_06505	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FXN58_06530	COG3623	hexulose-6-phosphate isomerase
FXN58_06535	COG0235	Class ii aldolase
FXN58_06575	COG0814	amino acid
FXN58_06585	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FXN58_06590	COG0778	Nitroreductase
FXN58_06605	COG2268	Band 7 protein
FXN58_06610	COG0114	fumarate hydratase activity
FXN58_06615	COG2927	DNA polymerase III (CHI subunit)
FXN58_06670	COG1566	PFAM secretion protein HlyD family protein
FXN58_06675	COG3293	Transposase
FXN58_06680	COG0783	Belongs to the Dps family
FXN58_06690	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FXN58_06695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FXN58_06700	COG0602	queuosine metabolic process
FXN58_06705	COG0720	synthase
FXN58_06745	COG0673	inositol 2-dehydrogenase activity
FXN58_06755	COG1879	ABC-type sugar transport system periplasmic component
FXN58_06760	COG1129	ABC transporter
FXN58_06765	COG1172	Belongs to the binding-protein-dependent transport system permease family
FXN58_06770	COG1012	belongs to the aldehyde dehydrogenase family
FXN58_06770	COG1454	alcohol dehydrogenase
FXN58_06775	COG3293	Transposase
FXN58_06785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FXN58_06790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FXN58_06795	COG1862	Preprotein translocase
FXN58_06805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FXN58_06830	COG2026	Addiction module toxin, RelE StbE family
FXN58_06850	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FXN58_06860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FXN58_06880	COG1620	l-lactate permease
FXN58_06895	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FXN58_06900	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FXN58_06910	COG4991	sh3 domain protein
FXN58_06915	COG0306	phosphate transporter
FXN58_06920	COG1392	Phosphate transport regulator
FXN58_06925	COG3025	triphosphatase activity
FXN58_06930	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FXN58_06935	COG0563	adenylate kinase activity
FXN58_06940	COG2814	Major facilitator Superfamily
FXN58_06945	COG0375	protein maturation
FXN58_06950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FXN58_06955	COG3152	Membrane
FXN58_06960	COG2252	PERMEase
FXN58_06975	COG0825	malonyl-CoA metabolic process
FXN58_06980	COG2351	hydroxyisourate hydrolase activity
FXN58_06995	COG3041	Addiction module toxin RelE StbE family
FXN58_07000	COG3077	Addiction module antitoxin, RelB DinJ family
FXN58_07010	COG3069	C4-dicarboxylate transmembrane transporter activity
FXN58_07030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FXN58_07035	COG0785	Cytochrome C biogenesis protein
FXN58_07040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FXN58_07040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FXN58_07045	COG0288	reversible hydration of carbon dioxide
FXN58_07050	COG2823	Periplasmic or secreted lipoprotein
FXN58_07055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FXN58_07060	COG0792	nuclease activity
FXN58_07070	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FXN58_07080	COG1252	NADH dehydrogenase
FXN58_07090	COG3293	Transposase
FXN58_07095	COG0616	signal peptide processing
FXN58_07100	COG2885	chlorophyll binding
FXN58_07100	COG3047	cAMP biosynthetic process
FXN58_07105	COG0625	glutathione transferase activity
FXN58_07110	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FXN58_07120	COG0187	DNA topoisomerase II activity
FXN58_07125	COG3293	Transposase
FXN58_07135	COG0488	(ABC) transporter
FXN58_07140	COG3683	transport system, periplasmic component
FXN58_07145	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FXN58_07165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FXN58_07170	COG3105	Protein conserved in bacteria
FXN58_07175	COG1944	ATP diphosphatase activity
FXN58_07185	COG3422	double-strand break repair
FXN58_07190	COG2190	(PTS) system
FXN58_07190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN58_07190	COG1263	PTS System
FXN58_07195	COG2226	methyltransferase
FXN58_07200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FXN58_07210	COG1846	Transcriptional regulator
FXN58_07210	COG1940	carbohydrate kinase activity
FXN58_07245	COG3293	Transposase
FXN58_07305	COG3293	Transposase
FXN58_07310	COG3008	intermembrane lipid transfer
FXN58_07315	COG2995	paraquat-inducible protein a
FXN58_07325	COG0793	Belongs to the peptidase S41A family
FXN58_07330	COG2989	Protein conserved in bacteria
FXN58_07335	COG3108	Peptidase M15
FXN58_07340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FXN58_07345	COG0567	Dehydrogenase, E1 component
FXN58_07350	COG0508	dehydrogenase complex catalyzes the overall conversion of
FXN58_07360	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FXN58_07395	COG3293	Transposase
FXN58_07420	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FXN58_07430	COG3260	NADH ubiquinone oxidoreductase 20
FXN58_07440	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FXN58_07440	COG3261	NADH dehydrogenase
FXN58_07445	COG0651	ATP synthesis coupled electron transport
FXN58_07450	COG4237	Hydrogenase 4 membrane
FXN58_07455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FXN58_07460	COG0650	Formate hydrogenlyase subunit 4
FXN58_07465	COG0651	ATP synthesis coupled electron transport
FXN58_07470	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FXN58_07480	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FXN58_07485	COG2864	formate dehydrogenase
FXN58_07490	COG0437	4 iron, 4 sulfur cluster binding
FXN58_07510	COG1609	Transcriptional regulator
FXN58_07515	COG3265	gluconokinase activity
FXN58_07520	COG2610	gluconate transmembrane transporter activity
FXN58_07525	COG0210	DNA helicase
FXN58_07530	COG1793	dna ligase
FXN58_07535	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FXN58_07540	COG4115	mRNA cleavage
FXN58_07545	COG2161	toxin-antitoxin pair type II binding
FXN58_07550	COG5039	Polysaccharide pyruvyl transferase
FXN58_07560	COG3293	Transposase
FXN58_07565	COG3306	glycosyltransferase involved in LPS biosynthesis
FXN58_07575	COG1216	Glycosyl transferase, family 2
FXN58_07580	COG1216	Glycosyl transferase, family 2
FXN58_07585	COG2951	lytic endotransglycosylase activity
FXN58_07590	COG0708	Exodeoxyribonuclease III
FXN58_07595	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FXN58_07605	COG3293	Transposase
FXN58_07615	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FXN58_07620	COG0671	phosphoesterase, PA-phosphatase related
FXN58_07640	COG0515	serine threonine protein kinase
FXN58_07645	COG1946	Acyl-CoA thioesterase
FXN58_07655	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FXN58_07660	COG4988	ABC transporter
FXN58_07665	COG0492	ferredoxin-NADP+ reductase activity
FXN58_07670	COG3118	belongs to the thioredoxin family
FXN58_07680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FXN58_07685	COG0303	'Molybdopterin
FXN58_07695	COG2027	D-alanyl-D-alanine carboxypeptidase
FXN58_07700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FXN58_07705	COG1534	Rna-binding protein
FXN58_07710	COG3657	addiction module killer protein
FXN58_07715	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FXN58_07720	COG0307	riboflavin synthase, alpha
FXN58_07730	COG4774	siderophore transport
FXN58_07735	COG4178	(ABC) transporter
FXN58_07740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FXN58_07745	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FXN58_07755	COG3102	Protein conserved in bacteria
FXN58_07760	COG3133	Outer membrane lipoprotein
FXN58_07765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FXN58_07770	COG2890	protein-(glutamine-N5) methyltransferase activity
FXN58_07780	COG3293	Transposase
FXN58_07785	COG0791	NLP P60 protein
FXN58_07795	COG3100	YcgL domain-containing protein
FXN58_07810	COG2062	phosphohistidine phosphatase, SixA
FXN58_07820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FXN58_07825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FXN58_07835	COG2932	Transcriptional regulator
FXN58_07845	COG0516	GMP reductase activity
FXN58_07845	COG0517	IMP dehydrogenase activity
FXN58_07885	COG4172	Belongs to the ABC transporter superfamily
FXN58_07890	COG4172	Belongs to the ABC transporter superfamily
FXN58_07895	COG4171	peptide transport system, permease
FXN58_07900	COG4168	peptide transport system, permease
FXN58_07905	COG4166	transmembrane transport
FXN58_07910	COG3106	COG3106 Predicted ATPase
FXN58_07920	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FXN58_07925	COG1923	regulation of RNA biosynthetic process
FXN58_07935	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FXN58_07940	COG1388	LysM domain
FXN58_07940	COG0860	N-Acetylmuramoyl-L-alanine amidase
FXN58_07945	COG0802	atpase or kinase
FXN58_07955	COG2246	polysaccharide biosynthetic process
FXN58_07965	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FXN58_07975	COG2194	sulfuric ester hydrolase activity
FXN58_07995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_08000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FXN58_08005	COG2190	(PTS) system
FXN58_08010	COG0339	signal peptide processing
FXN58_08015	COG2832	Protein of unknown function (DUF454)
FXN58_08020	COG4166	transmembrane transport
FXN58_08050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FXN58_08060	COG0512	Glutamine amidotransferase of anthranilate synthase
FXN58_08065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FXN58_08110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FXN58_08115	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FXN58_08125	COG3684	Belongs to the aldolase LacD family
FXN58_08135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_08140	COG3414	Phosphotransferase system galactitol-specific IIB component
FXN58_08145	COG3775	system Galactitol-specific IIC component
FXN58_08150	COG1063	alcohol dehydrogenase
FXN58_08155	COG1349	DNA-binding transcription factor activity
FXN58_08165	COG0142	geranyltranstransferase activity
FXN58_08180	COG0285	dihydrofolate synthase activity
FXN58_08185	COG0406	alpha-ribazole phosphatase activity
FXN58_08195	COG2431	L-lysine efflux transmembrane transporter activity
FXN58_08200	COG0564	pseudouridine synthase activity
FXN58_08210	COG2824	Alkylphosphonate utilization operon protein PhnA
FXN58_08220	COG1538	Outer membrane efflux protein
FXN58_08225	COG0577	efflux transmembrane transporter activity
FXN58_08225	COG1136	(ABC) transporter
FXN58_08230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FXN58_08275	COG4591	ABC-type transport system involved in lipoprotein release permease component
FXN58_08285	COG4591	ABC-type transport system involved in lipoprotein release permease component
FXN58_08290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FXN58_08295	COG0305	Participates in initiation and elongation during chromosome replication
FXN58_08305	COG0166	Belongs to the GPI family
FXN58_08320	COG3293	Transposase
FXN58_08325	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FXN58_08335	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FXN58_08340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FXN58_08345	COG1280	lysine exporter protein (LysE YggA)
FXN58_08360	COG0633	Ferredoxin
FXN58_08370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FXN58_08380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FXN58_08415	COG3293	Transposase
FXN58_08420	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN58_08430	COG3842	ATPase activity
FXN58_08435	COG0366	Alpha amylase catalytic
FXN58_08440	COG3833	ABC-type maltose transport systems, permease component
FXN58_08450	COG2182	Extracellular solute-binding protein
FXN58_08455	COG3842	ATPase activity
FXN58_08460	COG4580	involved in the transport of maltose and maltodextrins
FXN58_08475	COG1199	ATP-dependent helicase activity
FXN58_08480	COG1214	PFAM Peptidase M22, glycoprotease
FXN58_08485	COG3065	identical protein binding
FXN58_08490	COG0318	PFAM AMP-dependent synthetase and ligase
FXN58_08495	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FXN58_08500	COG1858	cytochrome C peroxidase
FXN58_08525	COG0330	HflC and HflK could
FXN58_08535	COG2249	NAD(P)H dehydrogenase (quinone) activity
FXN58_08540	COG3381	protein complex oligomerization
FXN58_08545	COG1560	Kdo2-lipid A biosynthetic process
FXN58_08550	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FXN58_08550	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FXN58_08555	COG2166	iron-sulfur cluster assembly
FXN58_08560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FXN58_08565	COG1525	nuclease
FXN58_08580	COG4774	siderophore transport
FXN58_08605	COG3585	molybdate ion transport
FXN58_08615	COG1120	ATPase activity
FXN58_08630	COG3293	Transposase
FXN58_08640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FXN58_08650	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FXN58_08655	COG0314	molybdopterin synthase activity
FXN58_08665	COG2969	positive regulation of protein catabolic process
FXN58_08675	COG1940	carbohydrate kinase activity
FXN58_08680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FXN58_08705	COG2390	Transcriptional regulator
FXN58_08710	COG3293	Transposase
FXN58_08730	COG1879	ABC-type sugar transport system periplasmic component
FXN58_08740	COG3293	Transposase
FXN58_08750	COG0469	pyruvate kinase activity
FXN58_08760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FXN58_08770	COG0133	tryptophan synthase activity
FXN58_08775	COG4221	oxidoreductase activity
FXN58_08810	COG3630	sodium ion export across plasma membrane
FXN58_08815	COG3293	Transposase
FXN58_08830	COG0298	carbon dioxide binding
FXN58_08840	COG0135	phosphoribosylanthranilate isomerase activity
FXN58_08840	COG0134	indole-3-glycerol-phosphate synthase activity
FXN58_08850	COG1942	4-Oxalocrotonate Tautomerase
FXN58_08855	COG0512	Glutamine amidotransferase of anthranilate synthase
FXN58_08860	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FXN58_08870	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FXN58_08870	COG0517	IMP dehydrogenase activity
FXN58_08885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FXN58_08900	COG0791	NLP P60 protein
FXN58_08915	COG0842	Transport permease protein
FXN58_08935	COG3293	Transposase
FXN58_08945	COG1448	Aminotransferase
FXN58_08950	COG0308	aminopeptidase N
FXN58_08955	COG0167	dihydroorotate dehydrogenase activity
FXN58_08960	COG0613	PHP domain protein
FXN58_08980	COG0589	response to stress
FXN58_08985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FXN58_08990	COG1528	Iron-storage protein
FXN58_08995	COG1528	Iron-storage protein
FXN58_09020	COG2925	Exonuclease
FXN58_09025	COG0697	spore germination
FXN58_09030	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FXN58_09035	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FXN58_09045	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FXN58_09050	COG1686	Belongs to the peptidase S11 family
FXN58_09060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FXN58_09065	COG0586	Pfam SNARE associated Golgi protein
FXN58_09085	COG3293	Transposase
FXN58_09095	COG3657	addiction module killer protein
FXN58_09110	COG1346	cytolysis
FXN58_09120	COG3293	Transposase
FXN58_09145	COG3293	Transposase
FXN58_09165	COG3005	denitrification pathway
FXN58_09170	COG0243	molybdopterin cofactor binding
FXN58_09175	COG2315	Protein conserved in bacteria
FXN58_09180	COG0471	metal ion transport
FXN58_09190	COG2026	Addiction module toxin, RelE StbE family
FXN58_09195	COG0101	tRNA pseudouridine synthase activity
FXN58_09215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FXN58_09220	COG1074	ATP-dependent DNA helicase activity
FXN58_09225	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FXN58_09235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FXN58_09240	COG1067	ATP-dependent peptidase activity
FXN58_09250	COG1278	Cold shock
FXN58_09265	COG3098	single-species biofilm formation
FXN58_09270	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FXN58_09285	COG3293	Transposase
FXN58_09295	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN58_09310	COG1178	ABC-type Fe3 transport system permease component
FXN58_09315	COG3842	ATPase activity
FXN58_09320	COG3101	peptidyl-lysine hydroxylation
FXN58_09325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FXN58_09335	COG0788	formyltetrahydrofolate deformylase activity
FXN58_09340	COG2916	Histone family protein nucleoid-structuring protein H-NS
FXN58_09345	COG1757	Na H antiporter
FXN58_09350	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FXN58_09360	COG0251	oxidation-reduction process
FXN58_09375	COG0463	Glycosyl transferase, family 2
FXN58_09385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FXN58_09395	COG1560	Kdo2-lipid A biosynthetic process
FXN58_09400	COG0730	response to heat
FXN58_09405	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FXN58_09410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FXN58_09415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FXN58_09415	COG3264	Mechanosensitive ion channel
FXN58_09420	COG0318	PFAM AMP-dependent synthetase and ligase
FXN58_09425	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FXN58_09430	COG0596	Alpha beta hydrolase
FXN58_09440	COG0716	FMN binding
FXN58_09445	COG0735	belongs to the Fur family
FXN58_09450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FXN58_09455	COG3094	Invasion gene expression up-regulator, SirB
FXN58_09460	COG0023	Translation Initiation Factor
FXN58_09470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FXN58_09475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FXN58_09480	COG0776	regulation of translation
FXN58_09485	COG0539	negative regulation of cytoplasmic translation
FXN58_09495	COG2990	Protein conserved in bacteria
FXN58_09505	COG0612	Peptidase, M16
FXN58_09510	COG1687	branched-chain amino acid
FXN58_09515	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FXN58_09520	COG0583	DNA-binding transcription factor activity
FXN58_09530	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FXN58_09575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FXN58_09580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FXN58_09595	COG3293	Transposase
FXN58_09600	COG0405	Gamma-glutamyltransferase
FXN58_09605	COG0642	Histidine kinase
FXN58_09610	COG0745	RESPONSE REGULATOR receiver
FXN58_09615	COG3111	PFAM Bacterial OB fold (BOF) protein
FXN58_09630	COG0737	Belongs to the 5'-nucleotidase family
FXN58_09635	COG4607	ABC-type enterochelin transport system periplasmic component
FXN58_09640	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FXN58_09645	COG4605	iron ion homeostasis
FXN58_09650	COG4604	ABC transporter, ATP-binding protein
FXN58_09655	COG0739	heme binding
FXN58_09665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FXN58_09670	COG0733	neurotransmitter:sodium symporter activity
FXN58_09675	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FXN58_09695	COG4656	Part of a membrane complex involved in electron transport
FXN58_09705	COG4657	Part of a membrane complex involved in electron transport
FXN58_09710	COG1090	epimerase
FXN58_09715	COG1438	arginine binding
FXN58_09720	COG0039	L-malate dehydrogenase activity
FXN58_09735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FXN58_09740	COG0583	DNA-binding transcription factor activity
FXN58_09750	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FXN58_09755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FXN58_09755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FXN58_09760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FXN58_09770	COG0471	metal ion transport
FXN58_09775	COG2005	Transcriptional regulator
FXN58_09780	COG0725	ABC transporter, periplasmic molybdate-binding protein
FXN58_09785	COG4149	molybdate abc transporter
FXN58_09800	COG0795	lipopolysaccharide-transporting ATPase activity
FXN58_09805	COG0795	lipopolysaccharide-transporting ATPase activity
FXN58_09810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FXN58_09815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FXN58_09840	COG3293	Transposase
FXN58_09850	COG0309	Hydrogenase expression formation protein (HypE)
FXN58_09860	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FXN58_09865	COG1122	ATPase activity
FXN58_09870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FXN58_09875	COG0310	cobalt ion transport
FXN58_09880	COG0310	cobalt ion transport
FXN58_09885	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
FXN58_09890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FXN58_09895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FXN58_09900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FXN58_09905	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FXN58_09920	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FXN58_09930	COG1609	Transcriptional regulator
FXN58_09935	COG2949	membrane
FXN58_09940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FXN58_09960	COG0583	DNA-binding transcription factor activity
FXN58_09970	COG0009	L-threonylcarbamoyladenylate synthase
FXN58_09975	COG1605	Chorismate mutase
FXN58_09975	COG0287	Prephenate dehydrogenase
FXN58_09980	COG0616	signal peptide processing
FXN58_09985	COG0778	Nitroreductase
FXN58_09990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FXN58_09995	COG0508	dehydrogenase complex catalyzes the overall conversion of
FXN58_10000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FXN58_10015	COG0058	SHG alpha-glucan phosphorylase activity
FXN58_10020	COG1640	4-alpha-glucanotransferase
FXN58_10025	COG1286	toxin biosynthetic process
FXN58_10030	COG3092	negative regulation of chromosome organization
FXN58_10035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FXN58_10040	COG0280	phosphate acetyltransferase
FXN58_10040	COG0857	belongs to the CobB CobQ family
FXN58_10050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FXN58_10055	COG0617	tRNA 3'-terminal CCA addition
FXN58_10065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FXN58_10070	COG3293	Transposase
FXN58_10085	COG1663	tetraacyldisaccharide 4'-kinase activity
FXN58_10090	COG2835	tetraacyldisaccharide 4'-kinase activity
FXN58_10100	COG0322	excinuclease ABC activity
FXN58_10110	COG0395	ABC-type sugar transport system, permease component
FXN58_10135	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FXN58_10140	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FXN58_10145	COG3293	Transposase
FXN58_10170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FXN58_10190	COG0195	Participates in both transcription termination and antitermination
FXN58_10275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FXN58_10280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FXN58_10290	COG0024	Methionine aminopeptidase
FXN58_10295	COG0316	Belongs to the HesB IscA family
FXN58_10305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FXN58_10310	COG0672	)-iron permease
FXN58_10325	COG0577	efflux transmembrane transporter activity
FXN58_10325	COG1136	(ABC) transporter
FXN58_10335	COG0577	efflux transmembrane transporter activity
FXN58_10335	COG1136	(ABC) transporter
FXN58_10340	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FXN58_10350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FXN58_10370	COG1643	Atp-dependent helicase
FXN58_10375	COG2363	Small membrane protein
FXN58_10395	COG3293	Transposase
FXN58_10400	COG0277	FAD linked oxidase domain protein
FXN58_10400	COG0247	lactate metabolic process
FXN58_10415	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FXN58_10420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FXN58_10425	COG0363	glucosamine-6-phosphate deaminase activity
FXN58_10430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FXN58_10435	COG1737	Transcriptional regulator
FXN58_10445	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FXN58_10450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FXN58_10465	COG1263	PTS System
FXN58_10465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN58_10465	COG2190	(PTS) system
FXN58_10505	COG3842	ATPase activity
FXN58_10510	COG1176	ABC-type spermidine putrescine transport system, permease component I
FXN58_10515	COG1177	transmembrane transport
FXN58_10520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FXN58_10535	COG3293	Transposase
FXN58_10545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FXN58_10560	COG1522	sequence-specific DNA binding
FXN58_10570	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FXN58_10575	COG1178	ABC-type Fe3 transport system permease component
FXN58_10580	COG4143	(ABC) transporter
FXN58_10625	COG2920	part of a sulfur-relay system
FXN58_10635	COG1121	(ABC) transporter
FXN58_10640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FXN58_10645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FXN58_10660	COG1803	Methylglyoxal synthase
FXN58_10665	COG3304	Inner membrane component domain
FXN58_10670	COG1289	transmembrane transporter activity
FXN58_10685	COG3958	Transketolase
FXN58_10690	COG3959	Transketolase, thiamine diphosphate binding domain
FXN58_10755	COG3293	Transposase
FXN58_10760	COG4953	penicillin-binding protein 1C
FXN58_10765	COG3293	Transposase
FXN58_10770	COG2855	membrane
FXN58_10785	COG0157	Belongs to the NadC ModD family
FXN58_10790	COG3842	ATPase activity
FXN58_10795	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FXN58_10800	COG0725	ABC transporter, periplasmic molybdate-binding protein
FXN58_10810	COG5339	Protein conserved in bacteria
FXN58_10815	COG0443	Heat shock 70 kDa protein
FXN58_10820	COG0484	heat shock protein binding
FXN58_10825	COG2337	Toxic component of a toxin-antitoxin (TA) module
FXN58_10840	COG0626	cystathionine gamma-synthase activity
FXN58_10845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FXN58_10920	COG0629	single-stranded DNA binding
FXN58_10965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FXN58_11205	COG2337	Toxic component of a toxin-antitoxin (TA) module
FXN58_11250	COG3021	interspecies interaction between organisms
FXN58_11280	COG3293	Transposase
FXN58_11290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FXN58_11310	COG2999	glutathione oxidoreductase activity
FXN58_11315	COG1530	ribonuclease E activity
FXN58_11320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FXN58_11345	COG3293	Transposase
FXN58_11355	COG3293	Transposase
FXN58_11380	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN58_11385	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN58_11410	COG3293	Transposase
FXN58_11435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FXN58_11445	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FXN58_11450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FXN58_11455	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FXN58_11460	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FXN58_11485	COG2850	peptidyl-arginine hydroxylation
FXN58_11500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN58_11505	COG1137	ATPase activity
FXN58_11510	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FXN58_11515	COG3117	lipopolysaccharide transmembrane transporter activity
FXN58_11520	COG1127	ABC transporter
FXN58_11525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FXN58_11530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FXN58_11535	COG2854	intermembrane phospholipid transfer
FXN58_11540	COG3113	response to antibiotic
FXN58_11545	COG5007	Belongs to the BolA IbaG family
FXN58_11565	COG3293	Transposase
FXN58_11570	COG3691	Protein conserved in bacteria
FXN58_11580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FXN58_11590	COG0861	Integral membrane protein TerC family
FXN58_11615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FXN58_11620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FXN58_11640	COG0517	IMP dehydrogenase activity
FXN58_11640	COG1125	glycine betaine transport
FXN58_11645	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FXN58_11655	COG0527	aspartate kinase activity
FXN58_11655	COG0460	homoserine dehydrogenase
FXN58_11670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FXN58_11675	COG2091	lysine biosynthetic process via aminoadipic acid
FXN58_11680	COG0330	HflC and HflK could
FXN58_11685	COG0330	HflC and HflK could
FXN58_11695	COG0544	peptidyl-prolyl cis-trans isomerase activity
FXN58_11700	COG4974	Belongs to the 'phage' integrase family
FXN58_11705	COG2814	Major facilitator Superfamily
FXN58_11710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FXN58_11725	COG3061	Opacity-associated protein A
FXN58_11725	COG3266	domain, Protein
FXN58_11730	COG1509	lysine 2,3-aminomutase activity
FXN58_11740	COG3293	Transposase
FXN58_11750	COG3033	Beta-eliminating lyase
FXN58_11760	COG2964	Protein conserved in bacteria
FXN58_11765	COG5413	integral membrane protein
FXN58_11780	COG0204	Acyl-transferase
FXN58_11790	COG0697	spore germination
FXN58_11795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FXN58_11800	COG1882	Formate acetyltransferase
FXN58_11805	COG2116	formate transmembrane transporter activity
FXN58_11810	COG3293	Transposase
FXN58_11815	COG0537	adenosine 5'-monophosphoramidase activity
FXN58_11850	COG3022	response to hydroperoxide
FXN58_11855	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FXN58_11870	COG0681	Belongs to the peptidase S26 family
FXN58_11905	COG0230	Belongs to the bacterial ribosomal protein bL34 family