locus-tag	class	description
FXN57_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FXN57_00010	COG0592	DNA-directed DNA polymerase activity
FXN57_00020	COG2226	methyltransferase
FXN57_00035	COG0281	malic enzyme
FXN57_00040	COG2081	HI0933 family
FXN57_00045	COG3088	subunit of a heme lyase
FXN57_00045	COG4235	cytochrome complex assembly
FXN57_00050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FXN57_00055	COG1138	Cytochrome C-type biogenesis protein
FXN57_00065	COG3301	Polysulphide reductase, NrfD
FXN57_00100	COG1138	Cytochrome C-type biogenesis protein
FXN57_00110	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FXN57_00115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FXN57_00120	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FXN57_00125	COG4133	protoheme IX ABC transporter activity
FXN57_00170	COG2267	carboxylic ester hydrolase activity
FXN57_00175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FXN57_00185	COG0436	Aminotransferase
FXN57_00200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FXN57_00205	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FXN57_00210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FXN57_00220	COG1652	LysM domain
FXN57_00225	COG2321	neutral zinc metallopeptidase
FXN57_00235	COG3293	Transposase
FXN57_00245	COG0280	phosphate acetyltransferase
FXN57_00245	COG0281	malic enzyme
FXN57_00250	COG3293	Transposase
FXN57_00325	COG3293	Transposase
FXN57_00335	COG2801	Transposase and inactivated derivatives
FXN57_00340	COG3091	SprT-like family
FXN57_00345	COG0814	amino acid
FXN57_00350	COG1760	l-serine dehydratase
FXN57_00355	COG0252	asparaginase activity
FXN57_00365	COG3063	Type IV pilus biogenesis stability protein PilW
FXN57_00370	COG1426	Protein conserved in bacteria
FXN57_00385	COG2976	Protein conserved in bacteria
FXN57_00395	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FXN57_00400	COG2233	PERMEase
FXN57_00405	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FXN57_00410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FXN57_00415	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FXN57_00425	COG0659	secondary active sulfate transmembrane transporter activity
FXN57_00445	COG2186	Transcriptional regulator
FXN57_00460	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FXN57_00485	COG0800	Aldolase
FXN57_00500	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FXN57_00505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FXN57_00515	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FXN57_00520	COG1555	photosystem II stabilization
FXN57_00530	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FXN57_00550	COG0196	riboflavin kinase activity
FXN57_00555	COG0728	peptidoglycan biosynthetic process
FXN57_00570	COG0560	Phosphoserine phosphatase
FXN57_00580	COG0193	aminoacyl-tRNA hydrolase activity
FXN57_00585	COG0012	GTP binding
FXN57_00595	COG1573	uracil-dna glycosylase
FXN57_00600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FXN57_00610	COG3115	cell septum assembly
FXN57_00630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FXN57_00635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FXN57_00645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FXN57_00670	COG2801	Transposase and inactivated derivatives
FXN57_00715	COG3161	chorismate lyase activity
FXN57_00725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FXN57_00730	COG1758	RNA polymerase activity
FXN57_00740	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FXN57_00775	COG2801	Transposase and inactivated derivatives
FXN57_00780	COG3293	Transposase
FXN57_00800	COG2271	Major facilitator Superfamily
FXN57_00810	COG1215	transferase activity, transferring glycosyl groups
FXN57_00815	COG0726	polysaccharide deacetylase
FXN57_00815	COG1649	PFAM Uncharacterised BCR, COG1649
FXN57_00830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FXN57_00835	COG0561	phosphatase activity
FXN57_00850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN57_00850	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_00855	COG0742	ribosomal rna small subunit methyltransferase
FXN57_00860	COG0552	protein localization to endoplasmic reticulum
FXN57_00865	COG2884	Cell division ATP-binding protein ftsE
FXN57_00870	COG2177	Part of the ABC transporter FtsEX involved in
FXN57_00895	COG1720	tRNA m6t6A37 methyltransferase activity
FXN57_00900	COG1575	Belongs to the MenA family. Type 1 subfamily
FXN57_00965	COG3293	Transposase
FXN57_00975	COG3028	Belongs to the UPF0307 family
FXN57_00980	COG0312	modulator of DNA gyrase
FXN57_00985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FXN57_00990	COG1929	Belongs to the glycerate kinase type-1 family
FXN57_00995	COG2610	gluconate transmembrane transporter activity
FXN57_01005	COG2801	Transposase and inactivated derivatives
FXN57_01015	COG0513	Belongs to the DEAD box helicase family
FXN57_01020	COG4785	May be involved in cell division
FXN57_01030	COG2731	YhcH YjgK YiaL family protein
FXN57_01035	COG3023	N-Acetylmuramoyl-L-alanine amidase
FXN57_01040	COG4969	Belongs to the N-Me-Phe pilin family
FXN57_01080	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FXN57_01100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FXN57_01105	COG0222	ribosome binding
FXN57_01140	COG0789	Transcriptional regulator
FXN57_01145	COG2608	mercury ion transmembrane transporter activity
FXN57_01150	COG2217	Heavy metal translocating P-type atpase
FXN57_01175	COG0740	serine-type endopeptidase activity
FXN57_01180	COG2194	sulfuric ester hydrolase activity
FXN57_01185	COG2918	glutathione biosynthetic process
FXN57_01185	COG1181	Belongs to the D-alanine--D-alanine ligase family
FXN57_01205	COG2801	Transposase and inactivated derivatives
FXN57_01225	COG0237	dephospho-CoA kinase activity
FXN57_01225	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FXN57_01230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FXN57_01240	COG1115	amino acid carrier protein
FXN57_01245	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FXN57_01280	COG4145	pantothenate transmembrane transporter activity
FXN57_01285	COG3924	membrane
FXN57_01300	COG3293	Transposase
FXN57_01305	COG0439	Biotin carboxylase
FXN57_01310	COG0511	ligase activity, forming carbon-carbon bonds
FXN57_01335	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FXN57_01345	COG0456	acetyltransferase
FXN57_01350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FXN57_01360	COG3078	GTPase activator activity
FXN57_01365	COG3501	Rhs element vgr protein
FXN57_01375	COG3201	nicotinamide mononucleotide transporter
FXN57_01385	COG0513	Belongs to the DEAD box helicase family
FXN57_01420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FXN57_01430	COG0251	oxidation-reduction process
FXN57_01435	COG2137	regulation of response to DNA damage stimulus
FXN57_01440	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FXN57_01455	COG3293	Transposase
FXN57_01525	COG1238	metal cluster binding
FXN57_01530	COG0110	maltose O-acetyltransferase activity
FXN57_01535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FXN57_01560	COG0210	DNA helicase
FXN57_01565	COG5645	(Lipo)protein
FXN57_01575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FXN57_01575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FXN57_01585	COG3293	Transposase
FXN57_01590	COG0243	molybdopterin cofactor binding
FXN57_01600	COG3302	dmso reductase anchor subunit
FXN57_01605	COG3293	Transposase
FXN57_01610	COG3381	protein complex oligomerization
FXN57_01615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FXN57_01615	COG2221	Nitrite and sulphite reductase 4Fe-4S
FXN57_01625	COG4545	Glutaredoxin-related protein
FXN57_01640	COG3293	Transposase
FXN57_01660	COG1114	Component of the transport system for branched-chain amino acids
FXN57_01670	COG3293	Transposase
FXN57_01675	COG0140	phosphoribosyl-ATP diphosphatase activity
FXN57_01675	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FXN57_01690	COG0561	phosphatase activity
FXN57_01695	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FXN57_01700	COG1596	polysaccharide export
FXN57_01700	COG1555	photosystem II stabilization
FXN57_01720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FXN57_01725	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FXN57_01735	COG1011	Hydrolase
FXN57_01815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FXN57_01825	COG1028	Short-chain dehydrogenase reductase Sdr
FXN57_01855	COG0737	Belongs to the 5'-nucleotidase family
FXN57_01865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FXN57_01875	COG0859	PFAM glycosyl transferase family 9
FXN57_01880	COG0754	glutathionylspermidine amidase activity
FXN57_01885	COG3005	denitrification pathway
FXN57_01890	COG3043	anaerobic respiration
FXN57_01895	COG0348	domain, Protein
FXN57_01900	COG0437	4 iron, 4 sulfur cluster binding
FXN57_01905	COG0243	molybdopterin cofactor binding
FXN57_01910	COG3062	negative regulation of establishment of protein localization
FXN57_01915	COG3850	Histidine kinase
FXN57_01920	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FXN57_01930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FXN57_01945	COG0582	viral genome integration into host DNA
FXN57_01955	COG1070	Carbohydrate kinase
FXN57_01960	COG2115	Belongs to the xylose isomerase family
FXN57_01965	COG4213	ABC transporter substrate-binding protein
FXN57_01970	COG1129	ABC transporter
FXN57_01980	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FXN57_01985	COG1757	Na H antiporter
FXN57_01990	COG1609	Transcriptional regulator
FXN57_01990	COG2207	Transcriptional regulator
FXN57_02000	COG0297	glycogen (starch) synthase activity
FXN57_02010	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FXN57_02020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FXN57_02040	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FXN57_02040	COG0662	Cupin 2, conserved barrel domain protein
FXN57_02045	COG2814	Major facilitator Superfamily
FXN57_02050	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN57_02050	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_02055	COG3715	PTS system
FXN57_02060	COG3716	PTS system mannose fructose sorbose family IID component
FXN57_02075	COG0859	PFAM glycosyl transferase family 9
FXN57_02080	COG1027	Aspartate ammonia-lyase
FXN57_02090	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FXN57_02095	COG0459	protein refolding
FXN57_02125	COG3293	Transposase
FXN57_02150	COG3293	Transposase
FXN57_02165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FXN57_02175	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FXN57_02180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FXN57_02195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FXN57_02205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FXN57_02225	COG3312	ion transport
FXN57_02235	COG1733	regulation of RNA biosynthetic process
FXN57_02250	COG0716	FMN binding
FXN57_02260	COG1494	fructose-1,6-bisphosphatase
FXN57_02270	COG1045	serine acetyltransferase
FXN57_02280	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FXN57_02285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FXN57_02290	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FXN57_02295	COG4988	ABC transporter
FXN57_02300	COG1132	(ABC) transporter
FXN57_02305	COG1309	transcriptional regulator
FXN57_02310	COG0583	DNA-binding transcription factor activity
FXN57_02315	COG0678	peroxiredoxin activity
FXN57_02315	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FXN57_02320	COG2900	Belongs to the SlyX family
FXN57_02325	COG0545	Peptidyl-prolyl cis-trans isomerase
FXN57_02330	COG2964	Protein conserved in bacteria
FXN57_02335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FXN57_02345	COG2168	tRNA wobble position uridine thiolation
FXN57_02350	COG1126	abc transporter atp-binding protein
FXN57_02355	COG0765	amino acid transport
FXN57_02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FXN57_02365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FXN57_02395	COG1686	Belongs to the peptidase S11 family
FXN57_02400	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FXN57_02400	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FXN57_02405	COG0772	Belongs to the SEDS family
FXN57_02410	COG0768	penicillin binding
FXN57_02420	COG0799	negative regulation of ribosome biogenesis
FXN57_02425	COG0513	Belongs to the DEAD box helicase family
FXN57_02430	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FXN57_02435	COG2814	Major facilitator Superfamily
FXN57_02445	COG1028	Short-chain dehydrogenase reductase Sdr
FXN57_02450	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FXN57_02460	COG0416	fatty acid biosynthetic process
FXN57_02465	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FXN57_02470	COG1399	metal-binding, possibly nucleic acid-binding protein
FXN57_02485	COG2830	Protein of unknown function (DUF452)
FXN57_02500	COG0688	phosphatidylethanolamine metabolic process
FXN57_02510	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FXN57_02515	COG3293	Transposase
FXN57_02520	COG2966	Psort location CytoplasmicMembrane, score
FXN57_02525	COG3610	response to peptide
FXN57_02530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FXN57_02605	COG2853	Lipoprotein
FXN57_02610	COG0747	negative chemotaxis
FXN57_02645	COG0814	amino acid
FXN57_02655	COG4783	chaperone-mediated protein folding
FXN57_02660	COG3293	Transposase
FXN57_02670	COG0848	biopolymer transport protein
FXN57_02675	COG0811	peptide transport
FXN57_02680	COG4536	flavin adenine dinucleotide binding
FXN57_02685	COG4137	Cytochrome C assembly protein
FXN57_02690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FXN57_02705	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FXN57_02710	COG0789	Transcriptional regulator
FXN57_02715	COG4221	oxidoreductase activity
FXN57_02725	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FXN57_02745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FXN57_02750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FXN57_02755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FXN57_02760	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FXN57_02765	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
FXN57_02780	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FXN57_02785	COG1466	dna polymerase III delta subunit
FXN57_02790	COG0494	nUDIX hydrolase
FXN57_02805	COG4701	Protein of unknown function (DUF721)
FXN57_02810	COG0789	Transcriptional regulator
FXN57_02815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FXN57_02835	COG3293	Transposase
FXN57_02850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FXN57_02865	COG4796	Type ii and iii secretion system protein
FXN57_02885	COG4972	Pilus assembly protein
FXN57_02890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FXN57_02895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FXN57_02900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FXN57_02915	COG1309	transcriptional regulator
FXN57_02925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FXN57_02940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FXN57_02960	COG3306	glycosyltransferase involved in LPS biosynthesis
FXN57_02970	COG3306	glycosyltransferase involved in LPS biosynthesis
FXN57_02985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FXN57_02995	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FXN57_03000	COG1309	transcriptional regulator
FXN57_03005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FXN57_03010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FXN57_03015	COG0500	methyltransferase
FXN57_03025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FXN57_03030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FXN57_03035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FXN57_03040	COG1381	Involved in DNA repair and RecF pathway recombination
FXN57_03045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FXN57_03065	COG0354	folic acid binding
FXN57_03070	COG1561	YicC-like family, N-terminal region
FXN57_03080	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FXN57_03095	COG3842	ATPase activity
FXN57_03100	COG1178	ABC-type Fe3 transport system permease component
FXN57_03105	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN57_03120	COG1194	a g-specific adenine glycosylase
FXN57_03125	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FXN57_03145	COG3056	Lipoprotein
FXN57_03150	COG0271	Belongs to the BolA IbaG family
FXN57_03165	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FXN57_03170	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FXN57_03175	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FXN57_03180	COG2871	sodium ion transport
FXN57_03185	COG1477	protein flavinylation
FXN57_03190	COG2991	Protein conserved in bacteria
FXN57_03205	COG0148	phosphopyruvate hydratase activity
FXN57_03220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FXN57_03225	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FXN57_03230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FXN57_03240	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FXN57_03255	COG3956	TIGRFAM MazG family protein
FXN57_03260	COG0402	S-adenosylhomocysteine deaminase activity
FXN57_03265	COG3083	sulfuric ester hydrolase activity
FXN57_03270	COG3082	Protein of unknown function (DUF1414)
FXN57_03280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FXN57_03285	COG0745	RESPONSE REGULATOR receiver
FXN57_03290	COG2205	protein histidine kinase activity
FXN57_03295	COG0786	glutamate:sodium symporter activity
FXN57_03310	COG3012	SEC-C Motif Domain Protein
FXN57_03315	COG2258	MOSC domain
FXN57_03330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FXN57_03335	COG1349	DNA-binding transcription factor activity
FXN57_03345	COG3068	Protein conserved in bacteria
FXN57_03350	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FXN57_03370	COG0248	Ppx GppA phosphatase
FXN57_03375	COG2911	Protein conserved in bacteria
FXN57_03380	COG0729	surface antigen
FXN57_03385	COG2197	response regulator
FXN57_03395	COG0181	hydroxymethylbilane synthase activity
FXN57_03405	COG2959	enzyme of heme biosynthesis
FXN57_03410	COG3071	HemY protein
FXN57_03415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FXN57_03425	COG1595	DNA-templated transcription, initiation
FXN57_03435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FXN57_03440	COG2183	response to ionizing radiation
FXN57_03450	COG0471	metal ion transport
FXN57_03455	COG0583	DNA-binding transcription factor activity
FXN57_03460	COG2183	response to ionizing radiation
FXN57_03465	COG3293	Transposase
FXN57_03475	COG1172	Belongs to the binding-protein-dependent transport system permease family
FXN57_03480	COG1129	ABC transporter
FXN57_03485	COG1879	ABC-type sugar transport system periplasmic component
FXN57_03490	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FXN57_03505	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FXN57_03515	COG0583	DNA-binding transcription factor activity
FXN57_03520	COG2962	Rard protein
FXN57_03535	COG0551	DNA topoisomerase type I activity
FXN57_03560	COG0705	Rhomboid family
FXN57_03565	COG1349	DNA-binding transcription factor activity
FXN57_03580	COG4178	(ABC) transporter
FXN57_03595	COG0233	cytoplasmic translational termination
FXN57_03610	COG0575	Belongs to the CDS family
FXN57_03625	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FXN57_03635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FXN57_03645	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FXN57_03655	COG0471	metal ion transport
FXN57_03655	COG0490	domain, Protein
FXN57_03670	COG4589	Belongs to the CDS family
FXN57_03675	COG0521	Mo-molybdopterin cofactor biosynthetic process
FXN57_03695	COG3276	selenocysteine insertion sequence binding
FXN57_03700	COG1921	L-seryl-tRNASec selenium transferase activity
FXN57_03705	COG0442	prolyl-tRNA aminoacylation
FXN57_03720	COG1595	DNA-templated transcription, initiation
FXN57_03725	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FXN57_03730	COG3026	antisigma factor binding
FXN57_03735	COG3086	response to oxidative stress
FXN57_03740	COG1763	Mo-molybdopterin cofactor biosynthetic process
FXN57_03745	COG0300	oxidoreductase activity
FXN57_03750	COG2195	Cleaves the N-terminal amino acid of tripeptides
FXN57_03760	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FXN57_03765	COG2818	Glycosylase
FXN57_03770	COG3477	response to acidic pH
FXN57_03775	COG0019	diaminopimelate decarboxylase activity
FXN57_03790	COG0514	ATP-dependent DNA helicase (RecQ)
FXN57_03795	COG0187	DNA topoisomerase II activity
FXN57_03800	COG1072	(Pantothenic acid kinase))
FXN57_03825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FXN57_03840	COG0561	phosphatase activity
FXN57_03845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FXN57_03850	COG2267	carboxylic ester hydrolase activity
FXN57_03855	COG3307	-O-antigen
FXN57_03860	COG0191	fructose-bisphosphate aldolase activity
FXN57_03870	COG3719	Belongs to the RNase T2 family
FXN57_03875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FXN57_03880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FXN57_03885	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FXN57_03900	COG0463	Glycosyl transferase, family 2
FXN57_03905	COG1519	Transferase
FXN57_03920	COG0859	PFAM glycosyl transferase family 9
FXN57_03925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FXN57_03930	COG1917	Cupin 2, conserved barrel domain protein
FXN57_03930	COG4977	sequence-specific DNA binding
FXN57_03935	COG1132	(ABC) transporter
FXN57_03970	COG0758	DNA mediated transformation
FXN57_03975	COG0584	glycerophosphoryl diester phosphodiesterase
FXN57_03980	COG2271	Major facilitator Superfamily
FXN57_03990	COG0557	exoribonuclease II activity
FXN57_03995	COG1077	Cell shape determining protein MreB Mrl
FXN57_04000	COG1792	Involved in formation and maintenance of cell shape
FXN57_04005	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FXN57_04035	COG0006	proline dipeptidase activity
FXN57_04055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FXN57_04080	COG0778	Nitroreductase
FXN57_04090	COG0762	integral membrane protein
FXN57_04110	COG0363	glucosamine-6-phosphate deaminase activity
FXN57_04115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FXN57_04120	COG1218	3'(2'),5'-bisphosphate nucleotidase
FXN57_04130	COG1297	OPT oligopeptide transporter protein
FXN57_04135	COG3293	Transposase
FXN57_04140	COG3059	membrane
FXN57_04145	COG1917	Cupin 2, conserved barrel domain protein
FXN57_04145	COG4977	sequence-specific DNA binding
FXN57_04150	COG0494	nUDIX hydrolase
FXN57_04155	COG1011	Hydrolase
FXN57_04160	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FXN57_04165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FXN57_04170	COG3293	Transposase
FXN57_04190	COG3293	Transposase
FXN57_04205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FXN57_04210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FXN57_04215	COG0805	protein transport
FXN57_04230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FXN57_04240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FXN57_04250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FXN57_04260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FXN57_04270	COG1841	ribosomal large subunit assembly
FXN57_04280	COG0201	protein transport
FXN57_04300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FXN57_04315	COG0814	amino acid
FXN57_04330	COG3423	Transcriptional regulator
FXN57_04345	COG2129	metallophosphoesterase
FXN57_04350	COG3172	ATPase kinase involved in NAD metabolism
FXN57_04365	COG1739	Uncharacterized protein family UPF0029
FXN57_04375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FXN57_04380	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
FXN57_04420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FXN57_04420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FXN57_04425	COG0569	domain protein
FXN57_04435	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FXN57_04450	COG2841	Protein conserved in bacteria
FXN57_04455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FXN57_04460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FXN57_04465	COG3036	rescue of stalled ribosome
FXN57_04475	COG1393	Belongs to the ArsC family
FXN57_04485	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FXN57_04490	COG1522	sequence-specific DNA binding
FXN57_04500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FXN57_04505	COG0038	chloride channel
FXN57_04510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FXN57_04515	COG0549	Belongs to the carbamate kinase family
FXN57_04520	COG1288	antiporter activity
FXN57_04530	COG0183	Belongs to the thiolase family
FXN57_04535	COG2031	fatty acid transporter
FXN57_04540	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FXN57_04545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FXN57_04555	COG0051	transcription antitermination factor activity, RNA binding
FXN57_04560	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FXN57_04565	COG0088	Forms part of the polypeptide exit tunnel
FXN57_04570	COG0089	rRNA binding
FXN57_04575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FXN57_04580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FXN57_04585	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FXN57_04590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FXN57_04595	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FXN57_04600	COG0255	Belongs to the universal ribosomal protein uL29 family
FXN57_04605	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FXN57_04615	COG2801	Transposase and inactivated derivatives
FXN57_04675	COG4964	Belongs to the GSP D family
FXN57_04705	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FXN57_04715	COG1444	tRNA N-acetyltransferase activity
FXN57_04720	COG3293	Transposase
FXN57_04725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FXN57_04735	COG1126	abc transporter atp-binding protein
FXN57_04740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FXN57_04745	COG4215	(ABC) transporter
FXN57_04750	COG4160	amino acid transport
FXN57_04755	COG1966	Carbon starvation protein
FXN57_04770	COG3116	cell division
FXN57_04775	COG0768	penicillin binding
FXN57_04785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FXN57_04795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FXN57_04805	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FXN57_04820	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FXN57_04825	COG0849	cell division
FXN57_04830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FXN57_04840	COG0077	Prephenate dehydratase
FXN57_04840	COG1605	Chorismate mutase
FXN57_04845	COG0326	Molecular chaperone. Has ATPase activity
FXN57_04850	COG1393	Belongs to the ArsC family
FXN57_04860	COG1876	peptidase activity
FXN57_04865	COG0494	nUDIX hydrolase
FXN57_04870	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FXN57_04915	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FXN57_04925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FXN57_04930	COG1053	succinate dehydrogenase
FXN57_04945	COG1120	ATPase activity
FXN57_04950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FXN57_04960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FXN57_04975	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FXN57_04980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FXN57_05010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FXN57_05020	COG0741	lytic transglycosylase activity
FXN57_05025	COG2350	Protein conserved in bacteria
FXN57_05030	COG1607	acyl-coa hydrolase
FXN57_05035	COG2917	probably involved in intracellular septation
FXN57_05045	COG3293	Transposase
FXN57_05055	COG0497	DNA recombination
FXN57_05065	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FXN57_05080	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FXN57_05080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FXN57_05085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FXN57_05090	COG0784	Response regulator, receiver
FXN57_05090	COG2198	Histidine kinase
FXN57_05090	COG5002	protein histidine kinase activity
FXN57_05095	COG3293	Transposase
FXN57_05110	COG1879	ABC-type sugar transport system periplasmic component
FXN57_05115	COG1609	Transcriptional regulator
FXN57_05120	COG1085	galactose-1-phosphate uridylyltransferase
FXN57_05125	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FXN57_05130	COG2017	converts alpha-aldose to the beta-anomer
FXN57_05145	COG0471	metal ion transport
FXN57_05150	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FXN57_05150	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
FXN57_05155	COG3051	citrate lyase alpha subunit
FXN57_05160	COG2301	Belongs to the HpcH HpaI aldolase family
FXN57_05170	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FXN57_05175	COG4535	Mg2 and Co2 transporter CorC
FXN57_05195	COG0105	UTP biosynthetic process
FXN57_05215	COG1388	LysM domain
FXN57_05215	COG4942	peptidase
FXN57_05225	COG1238	metal cluster binding
FXN57_05255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FXN57_05270	COG3293	Transposase
FXN57_05285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FXN57_05295	COG0733	neurotransmitter:sodium symporter activity
FXN57_05305	COG1285	pathogenesis
FXN57_05310	COG2801	Transposase and inactivated derivatives
FXN57_05355	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FXN57_05355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FXN57_05355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FXN57_05360	COG1105	Belongs to the carbohydrate kinase PfkB family
FXN57_05365	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_05365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_05375	COG0746	molybdenum cofactor guanylyltransferase activity
FXN57_05380	COG3084	Protein conserved in bacteria
FXN57_05385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FXN57_05390	COG3085	chromosome segregation
FXN57_05445	COG0561	phosphatase activity
FXN57_05455	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FXN57_05465	COG2610	gluconate transmembrane transporter activity
FXN57_05470	COG3622	Belongs to the hyi family
FXN57_05475	COG0235	Class ii aldolase
FXN57_05480	COG3395	kinase activity
FXN57_05485	COG2084	Dehydrogenase
FXN57_05490	COG1349	DNA-binding transcription factor activity
FXN57_05495	COG0347	Belongs to the P(II) protein family
FXN57_05500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FXN57_05505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FXN57_05510	COG0470	DNA polymerase III
FXN57_05515	COG0084	hydrolase, TatD family'
FXN57_05525	COG1253	flavin adenine dinucleotide binding
FXN57_05530	COG3293	Transposase
FXN57_05555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FXN57_05560	COG4942	peptidase
FXN57_05565	COG2861	carbohydrate metabolic process
FXN57_05570	COG0606	chelatase, subunit chli
FXN57_05660	COG3209	COG3209 Rhs family protein
FXN57_05675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FXN57_05705	COG2990	Protein conserved in bacteria
FXN57_05710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FXN57_05730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FXN57_05805	COG0195	Participates in both transcription termination and antitermination
FXN57_05825	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FXN57_05850	COG3293	Transposase
FXN57_05855	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FXN57_05860	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FXN57_05875	COG3842	ATPase activity
FXN57_05885	COG0395	ABC-type sugar transport system, permease component
FXN57_05895	COG0322	excinuclease ABC activity
FXN57_05905	COG2835	tetraacyldisaccharide 4'-kinase activity
FXN57_05910	COG1663	tetraacyldisaccharide 4'-kinase activity
FXN57_05925	COG3293	Transposase
FXN57_05930	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FXN57_05940	COG0617	tRNA 3'-terminal CCA addition
FXN57_05945	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FXN57_05955	COG0280	phosphate acetyltransferase
FXN57_05955	COG0857	belongs to the CobB CobQ family
FXN57_05960	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FXN57_05965	COG3092	negative regulation of chromosome organization
FXN57_05970	COG1286	toxin biosynthetic process
FXN57_05975	COG1640	4-alpha-glucanotransferase
FXN57_05980	COG0058	SHG alpha-glucan phosphorylase activity
FXN57_05985	COG2909	trisaccharide binding
FXN57_05995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FXN57_06000	COG0508	dehydrogenase complex catalyzes the overall conversion of
FXN57_06005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FXN57_06010	COG0778	Nitroreductase
FXN57_06015	COG0616	signal peptide processing
FXN57_06020	COG1605	Chorismate mutase
FXN57_06020	COG0287	Prephenate dehydrogenase
FXN57_06025	COG0009	L-threonylcarbamoyladenylate synthase
FXN57_06035	COG0583	DNA-binding transcription factor activity
FXN57_06055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FXN57_06060	COG2949	membrane
FXN57_06065	COG1609	Transcriptional regulator
FXN57_06080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FXN57_06095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FXN57_06100	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FXN57_06105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FXN57_06110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FXN57_06115	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
FXN57_06120	COG0310	cobalt ion transport
FXN57_06125	COG0310	cobalt ion transport
FXN57_06130	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FXN57_06135	COG1122	ATPase activity
FXN57_06140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FXN57_06150	COG0309	Hydrogenase expression formation protein (HypE)
FXN57_06160	COG3293	Transposase
FXN57_06185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FXN57_06190	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FXN57_06195	COG0795	lipopolysaccharide-transporting ATPase activity
FXN57_06200	COG0795	lipopolysaccharide-transporting ATPase activity
FXN57_06215	COG4149	molybdate abc transporter
FXN57_06220	COG0725	ABC transporter, periplasmic molybdate-binding protein
FXN57_06225	COG2005	Transcriptional regulator
FXN57_06230	COG0471	metal ion transport
FXN57_06240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FXN57_06245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FXN57_06245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FXN57_06250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FXN57_06260	COG0583	DNA-binding transcription factor activity
FXN57_06265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FXN57_06280	COG0039	L-malate dehydrogenase activity
FXN57_06285	COG1438	arginine binding
FXN57_06290	COG1090	epimerase
FXN57_06295	COG4657	Part of a membrane complex involved in electron transport
FXN57_06325	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FXN57_06330	COG0733	neurotransmitter:sodium symporter activity
FXN57_06335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FXN57_06345	COG0739	heme binding
FXN57_06350	COG4604	ABC transporter, ATP-binding protein
FXN57_06355	COG4605	iron ion homeostasis
FXN57_06360	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FXN57_06365	COG4607	ABC-type enterochelin transport system periplasmic component
FXN57_06370	COG0737	Belongs to the 5'-nucleotidase family
FXN57_06385	COG3111	PFAM Bacterial OB fold (BOF) protein
FXN57_06390	COG0745	RESPONSE REGULATOR receiver
FXN57_06395	COG0642	Histidine kinase
FXN57_06400	COG0405	Gamma-glutamyltransferase
FXN57_06405	COG3293	Transposase
FXN57_06420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FXN57_06425	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FXN57_06470	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FXN57_06480	COG0583	DNA-binding transcription factor activity
FXN57_06485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FXN57_06490	COG1687	branched-chain amino acid
FXN57_06495	COG0612	Peptidase, M16
FXN57_06505	COG2990	Protein conserved in bacteria
FXN57_06515	COG0539	negative regulation of cytoplasmic translation
FXN57_06520	COG0776	regulation of translation
FXN57_06525	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FXN57_06530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FXN57_06540	COG0023	Translation Initiation Factor
FXN57_06545	COG3094	Invasion gene expression up-regulator, SirB
FXN57_06550	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FXN57_06555	COG0735	belongs to the Fur family
FXN57_06560	COG0716	FMN binding
FXN57_06570	COG0596	Alpha beta hydrolase
FXN57_06575	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FXN57_06580	COG0318	PFAM AMP-dependent synthetase and ligase
FXN57_06585	COG3264	Mechanosensitive ion channel
FXN57_06585	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FXN57_06590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FXN57_06595	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FXN57_06600	COG0730	response to heat
FXN57_06605	COG1560	Kdo2-lipid A biosynthetic process
FXN57_06615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FXN57_06625	COG0463	Glycosyl transferase, family 2
FXN57_06635	COG0251	oxidation-reduction process
FXN57_06645	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FXN57_06650	COG1757	Na H antiporter
FXN57_06655	COG2916	Histone family protein nucleoid-structuring protein H-NS
FXN57_06660	COG0788	formyltetrahydrofolate deformylase activity
FXN57_06670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FXN57_06680	COG3842	ATPase activity
FXN57_06700	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN57_06715	COG3293	Transposase
FXN57_06730	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FXN57_06735	COG3098	single-species biofilm formation
FXN57_06750	COG1278	Cold shock
FXN57_06760	COG1067	ATP-dependent peptidase activity
FXN57_06765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FXN57_06775	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FXN57_06780	COG1074	ATP-dependent DNA helicase activity
FXN57_06785	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FXN57_06805	COG0101	tRNA pseudouridine synthase activity
FXN57_06810	COG2026	Addiction module toxin, RelE StbE family
FXN57_06820	COG0471	metal ion transport
FXN57_06825	COG2315	Protein conserved in bacteria
FXN57_06830	COG0243	molybdopterin cofactor binding
FXN57_06835	COG3005	denitrification pathway
FXN57_06855	COG3293	Transposase
FXN57_06880	COG3293	Transposase
FXN57_06890	COG1448	Aminotransferase
FXN57_06895	COG0308	aminopeptidase N
FXN57_06900	COG0167	dihydroorotate dehydrogenase activity
FXN57_06905	COG0613	PHP domain protein
FXN57_06925	COG0589	response to stress
FXN57_06930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FXN57_06935	COG1528	Iron-storage protein
FXN57_06940	COG1528	Iron-storage protein
FXN57_06965	COG2925	Exonuclease
FXN57_06970	COG0697	spore germination
FXN57_06975	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FXN57_06980	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FXN57_06990	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FXN57_06995	COG1686	Belongs to the peptidase S11 family
FXN57_07005	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FXN57_07010	COG0586	Pfam SNARE associated Golgi protein
FXN57_07015	COG0058	SHG alpha-glucan phosphorylase activity
FXN57_07030	COG3293	Transposase
FXN57_07040	COG3657	addiction module killer protein
FXN57_07055	COG1346	cytolysis
FXN57_07065	COG3293	Transposase
FXN57_07080	COG0842	Transport permease protein
FXN57_07080	COG1129	ABC transporter
FXN57_07085	COG0842	Transport permease protein
FXN57_07100	COG0791	NLP P60 protein
FXN57_07115	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FXN57_07130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FXN57_07130	COG0517	IMP dehydrogenase activity
FXN57_07140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FXN57_07145	COG0512	Glutamine amidotransferase of anthranilate synthase
FXN57_07150	COG1942	4-Oxalocrotonate Tautomerase
FXN57_07160	COG0135	phosphoribosylanthranilate isomerase activity
FXN57_07160	COG0134	indole-3-glycerol-phosphate synthase activity
FXN57_07170	COG0298	carbon dioxide binding
FXN57_07185	COG3293	Transposase
FXN57_07190	COG3630	sodium ion export across plasma membrane
FXN57_07225	COG4221	oxidoreductase activity
FXN57_07230	COG0133	tryptophan synthase activity
FXN57_07240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FXN57_07250	COG0469	pyruvate kinase activity
FXN57_07260	COG3293	Transposase
FXN57_07270	COG1879	ABC-type sugar transport system periplasmic component
FXN57_07290	COG3293	Transposase
FXN57_07315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FXN57_07320	COG1940	carbohydrate kinase activity
FXN57_07330	COG2969	positive regulation of protein catabolic process
FXN57_07340	COG0314	molybdopterin synthase activity
FXN57_07345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FXN57_07355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FXN57_07365	COG3293	Transposase
FXN57_07380	COG1120	ATPase activity
FXN57_07390	COG3585	molybdate ion transport
FXN57_07415	COG4774	siderophore transport
FXN57_07430	COG1525	nuclease
FXN57_07435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FXN57_07440	COG2166	iron-sulfur cluster assembly
FXN57_07445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FXN57_07445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FXN57_07450	COG1560	Kdo2-lipid A biosynthetic process
FXN57_07455	COG3381	protein complex oligomerization
FXN57_07460	COG2249	NAD(P)H dehydrogenase (quinone) activity
FXN57_07470	COG0330	HflC and HflK could
FXN57_07495	COG1858	cytochrome C peroxidase
FXN57_07500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FXN57_07505	COG0318	PFAM AMP-dependent synthetase and ligase
FXN57_07510	COG3065	identical protein binding
FXN57_07515	COG1214	PFAM Peptidase M22, glycoprotease
FXN57_07520	COG1199	ATP-dependent helicase activity
FXN57_07535	COG4580	involved in the transport of maltose and maltodextrins
FXN57_07540	COG3842	ATPase activity
FXN57_07545	COG2182	Extracellular solute-binding protein
FXN57_07555	COG3833	ABC-type maltose transport systems, permease component
FXN57_07560	COG0366	Alpha amylase catalytic
FXN57_07565	COG3842	ATPase activity
FXN57_07575	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN57_07580	COG3293	Transposase
FXN57_07595	COG0732	type I restriction modification DNA specificity domain
FXN57_07625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FXN57_07635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FXN57_07645	COG0633	Ferredoxin
FXN57_07660	COG1280	lysine exporter protein (LysE YggA)
FXN57_07665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FXN57_07670	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FXN57_07680	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FXN57_07685	COG3293	Transposase
FXN57_07700	COG0166	Belongs to the GPI family
FXN57_07710	COG0305	Participates in initiation and elongation during chromosome replication
FXN57_07715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FXN57_07720	COG4591	ABC-type transport system involved in lipoprotein release permease component
FXN57_07730	COG4591	ABC-type transport system involved in lipoprotein release permease component
FXN57_07750	COG3293	Transposase
FXN57_07780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FXN57_07785	COG0577	efflux transmembrane transporter activity
FXN57_07785	COG1136	(ABC) transporter
FXN57_07790	COG1538	Outer membrane efflux protein
FXN57_07800	COG2824	Alkylphosphonate utilization operon protein PhnA
FXN57_07810	COG0564	pseudouridine synthase activity
FXN57_07815	COG2431	L-lysine efflux transmembrane transporter activity
FXN57_07825	COG0406	alpha-ribazole phosphatase activity
FXN57_07830	COG0285	dihydrofolate synthase activity
FXN57_07845	COG0142	geranyltranstransferase activity
FXN57_07855	COG1349	DNA-binding transcription factor activity
FXN57_07860	COG1063	alcohol dehydrogenase
FXN57_07865	COG3775	system Galactitol-specific IIC component
FXN57_07870	COG3414	Phosphotransferase system galactitol-specific IIB component
FXN57_07875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_07885	COG3684	Belongs to the aldolase LacD family
FXN57_07895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FXN57_07900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FXN57_07950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FXN57_07955	COG0512	Glutamine amidotransferase of anthranilate synthase
FXN57_07965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FXN57_07995	COG4166	transmembrane transport
FXN57_08000	COG2832	Protein of unknown function (DUF454)
FXN57_08005	COG0339	signal peptide processing
FXN57_08010	COG2190	(PTS) system
FXN57_08015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FXN57_08020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_08045	COG2194	sulfuric ester hydrolase activity
FXN57_08055	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FXN57_08065	COG2246	polysaccharide biosynthetic process
FXN57_08075	COG0802	atpase or kinase
FXN57_08080	COG1388	LysM domain
FXN57_08080	COG0860	N-Acetylmuramoyl-L-alanine amidase
FXN57_08095	COG1923	regulation of RNA biosynthetic process
FXN57_08100	COG3283	Transcriptional regulator of aromatic amino acids metabolism
FXN57_08110	COG3106	COG3106 Predicted ATPase
FXN57_08115	COG4166	transmembrane transport
FXN57_08120	COG4168	peptide transport system, permease
FXN57_08125	COG4171	peptide transport system, permease
FXN57_08130	COG4172	Belongs to the ABC transporter superfamily
FXN57_08135	COG4172	Belongs to the ABC transporter superfamily
FXN57_08175	COG0516	GMP reductase activity
FXN57_08175	COG0517	IMP dehydrogenase activity
FXN57_08185	COG2932	Transcriptional regulator
FXN57_08195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FXN57_08200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FXN57_08210	COG2062	phosphohistidine phosphatase, SixA
FXN57_08225	COG3100	YcgL domain-containing protein
FXN57_08235	COG0791	NLP P60 protein
FXN57_08245	COG2890	protein-(glutamine-N5) methyltransferase activity
FXN57_08250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FXN57_08255	COG3133	Outer membrane lipoprotein
FXN57_08260	COG3102	Protein conserved in bacteria
FXN57_08270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FXN57_08275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FXN57_08280	COG4178	(ABC) transporter
FXN57_08285	COG4774	siderophore transport
FXN57_08295	COG0307	riboflavin synthase, alpha
FXN57_08300	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FXN57_08305	COG3657	addiction module killer protein
FXN57_08310	COG1534	Rna-binding protein
FXN57_08315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FXN57_08320	COG2027	D-alanyl-D-alanine carboxypeptidase
FXN57_08330	COG0303	'Molybdopterin
FXN57_08335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FXN57_08345	COG3118	belongs to the thioredoxin family
FXN57_08350	COG0492	ferredoxin-NADP+ reductase activity
FXN57_08355	COG4988	ABC transporter
FXN57_08360	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FXN57_08370	COG1946	Acyl-CoA thioesterase
FXN57_08375	COG0515	serine threonine protein kinase
FXN57_08395	COG0671	phosphoesterase, PA-phosphatase related
FXN57_08400	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FXN57_08415	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FXN57_08420	COG0708	Exodeoxyribonuclease III
FXN57_08425	COG2951	lytic endotransglycosylase activity
FXN57_08430	COG1216	Glycosyl transferase, family 2
FXN57_08435	COG1216	Glycosyl transferase, family 2
FXN57_08445	COG3306	glycosyltransferase involved in LPS biosynthesis
FXN57_08450	COG3293	Transposase
FXN57_08460	COG5039	Polysaccharide pyruvyl transferase
FXN57_08465	COG2161	toxin-antitoxin pair type II binding
FXN57_08470	COG4115	mRNA cleavage
FXN57_08475	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FXN57_08480	COG1793	dna ligase
FXN57_08485	COG0210	DNA helicase
FXN57_08490	COG2610	gluconate transmembrane transporter activity
FXN57_08495	COG3265	gluconokinase activity
FXN57_08500	COG1609	Transcriptional regulator
FXN57_08520	COG0437	4 iron, 4 sulfur cluster binding
FXN57_08525	COG2864	formate dehydrogenase
FXN57_08530	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FXN57_08540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FXN57_08550	COG0650	Formate hydrogenlyase subunit 4
FXN57_08555	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FXN57_08560	COG4237	Hydrogenase 4 membrane
FXN57_08565	COG0651	ATP synthesis coupled electron transport
FXN57_08570	COG3261	NADH dehydrogenase
FXN57_08570	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FXN57_08580	COG3260	NADH ubiquinone oxidoreductase 20
FXN57_08590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FXN57_08645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FXN57_08655	COG0508	dehydrogenase complex catalyzes the overall conversion of
FXN57_08660	COG0567	Dehydrogenase, E1 component
FXN57_08665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FXN57_08670	COG3108	Peptidase M15
FXN57_08675	COG2989	Protein conserved in bacteria
FXN57_08680	COG0793	Belongs to the peptidase S41A family
FXN57_08690	COG2995	paraquat-inducible protein a
FXN57_08695	COG3008	intermembrane lipid transfer
FXN57_08760	COG3293	Transposase
FXN57_08800	COG1940	carbohydrate kinase activity
FXN57_08800	COG1846	Transcriptional regulator
FXN57_08810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FXN57_08815	COG2226	methyltransferase
FXN57_08825	COG3422	double-strand break repair
FXN57_08835	COG1944	ATP diphosphatase activity
FXN57_08840	COG3105	Protein conserved in bacteria
FXN57_08845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FXN57_08865	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FXN57_08870	COG3683	transport system, periplasmic component
FXN57_08875	COG0488	(ABC) transporter
FXN57_08885	COG3293	Transposase
FXN57_08890	COG0187	DNA topoisomerase II activity
FXN57_08900	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FXN57_08905	COG0625	glutathione transferase activity
FXN57_08910	COG2885	chlorophyll binding
FXN57_08910	COG3047	cAMP biosynthetic process
FXN57_08915	COG0616	signal peptide processing
FXN57_08920	COG3293	Transposase
FXN57_08930	COG1252	NADH dehydrogenase
FXN57_08940	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FXN57_08950	COG0792	nuclease activity
FXN57_08955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FXN57_08960	COG2823	Periplasmic or secreted lipoprotein
FXN57_08965	COG0288	reversible hydration of carbon dioxide
FXN57_08970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FXN57_08970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FXN57_08975	COG0785	Cytochrome C biogenesis protein
FXN57_08980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FXN57_09000	COG3069	C4-dicarboxylate transmembrane transporter activity
FXN57_09010	COG3077	Addiction module antitoxin, RelB DinJ family
FXN57_09015	COG3041	Addiction module toxin RelE StbE family
FXN57_09030	COG2351	hydroxyisourate hydrolase activity
FXN57_09035	COG0825	malonyl-CoA metabolic process
FXN57_09050	COG2252	PERMEase
FXN57_09055	COG3152	Membrane
FXN57_09060	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FXN57_09065	COG0375	protein maturation
FXN57_09070	COG2814	Major facilitator Superfamily
FXN57_09075	COG0563	adenylate kinase activity
FXN57_09080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FXN57_09085	COG3025	triphosphatase activity
FXN57_09090	COG1392	Phosphate transport regulator
FXN57_09095	COG0306	phosphate transporter
FXN57_09100	COG4991	sh3 domain protein
FXN57_09110	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FXN57_09115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FXN57_09130	COG1620	l-lactate permease
FXN57_09150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FXN57_09160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FXN57_09180	COG2026	Addiction module toxin, RelE StbE family
FXN57_09205	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FXN57_09215	COG1862	Preprotein translocase
FXN57_09220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FXN57_09225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FXN57_09235	COG3293	Transposase
FXN57_09240	COG1012	belongs to the aldehyde dehydrogenase family
FXN57_09240	COG1454	alcohol dehydrogenase
FXN57_09245	COG1172	Belongs to the binding-protein-dependent transport system permease family
FXN57_09250	COG1129	ABC transporter
FXN57_09255	COG1879	ABC-type sugar transport system periplasmic component
FXN57_09265	COG0673	inositol 2-dehydrogenase activity
FXN57_09305	COG0720	synthase
FXN57_09310	COG0602	queuosine metabolic process
FXN57_09315	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FXN57_09320	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FXN57_09370	COG0783	Belongs to the Dps family
FXN57_09375	COG3293	Transposase
FXN57_09380	COG1566	PFAM secretion protein HlyD family protein
FXN57_09435	COG2927	DNA polymerase III (CHI subunit)
FXN57_09440	COG0114	fumarate hydratase activity
FXN57_09445	COG2268	Band 7 protein
FXN57_09460	COG0778	Nitroreductase
FXN57_09465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FXN57_09475	COG0814	amino acid
FXN57_09515	COG0235	Class ii aldolase
FXN57_09520	COG3623	hexulose-6-phosphate isomerase
FXN57_09545	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
FXN57_09570	COG3293	Transposase
FXN57_09585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FXN57_09590	COG3962	Belongs to the TPP enzyme family
FXN57_09600	COG0673	inositol 2-dehydrogenase activity
FXN57_09605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FXN57_09610	COG2274	protein secretion by the type I secretion system
FXN57_09615	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FXN57_09620	COG2994	toxin metabolic process
FXN57_09630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FXN57_09650	COG2813	Specifically methylates the guanine in position
FXN57_09655	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FXN57_09660	COG0456	acetyltransferase
FXN57_09665	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FXN57_09680	COG4795	General secretion pathway protein
FXN57_09705	COG3064	Membrane
FXN57_09710	COG0848	biopolymer transport protein
FXN57_09715	COG0811	peptide transport
FXN57_09720	COG0824	Thioesterase
FXN57_09735	COG1294	oxidase, subunit
FXN57_09740	COG1271	oxidase subunit
FXN57_09770	COG0217	transcriptional regulatory protein
FXN57_09775	COG0494	nUDIX hydrolase
FXN57_09785	COG3293	Transposase
FXN57_09795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FXN57_09800	COG1755	Isoprenylcysteine carboxyl methyltransferase
FXN57_09815	COG2271	Major facilitator Superfamily
FXN57_09820	COG4771	TonB-dependent receptor
FXN57_09825	COG0346	lactoylglutathione lyase activity
FXN57_09830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FXN57_09835	COG2056	Na+-H+ antiporter family
FXN57_09860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FXN57_09865	COG0142	geranyltranstransferase activity
FXN57_09885	COG0697	spore germination
FXN57_09890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FXN57_09900	COG4166	transmembrane transport
FXN57_09905	COG0601	transmembrane transport
FXN57_09910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FXN57_09915	COG0444	Belongs to the ABC transporter superfamily
FXN57_09920	COG4608	Belongs to the ABC transporter superfamily
FXN57_09925	COG0745	RESPONSE REGULATOR receiver
FXN57_09930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FXN57_09940	COG1611	Belongs to the LOG family
FXN57_09950	COG3293	Transposase
FXN57_09955	COG2259	Doxx family
FXN57_09965	COG1530	ribonuclease E activity
FXN57_09985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FXN57_09990	COG0626	cystathionine gamma-synthase activity
FXN57_10030	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FXN57_10035	COG1959	2 iron, 2 sulfur cluster binding
FXN57_10045	COG0822	iron-sulfur transferase activity
FXN57_10050	COG3293	Transposase
FXN57_10065	COG0443	Heat shock 70 kDa protein
FXN57_10070	COG0633	Ferredoxin
FXN57_10075	COG2975	iron-sulfur cluster assembly
FXN57_10080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FXN57_10080	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FXN57_10085	COG0489	protein tyrosine kinase activity
FXN57_10115	COG0590	tRNA wobble adenosine to inosine editing
FXN57_10120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FXN57_10130	COG0730	response to heat
FXN57_10140	COG1869	D-ribose catabolic process
FXN57_10155	COG3617	BRO family, N-terminal domain
FXN57_10170	COG1598	PFAM Uncharacterised protein family UPF0150
FXN57_10205	COG0582	viral genome integration into host DNA
FXN57_10240	COG0165	Argininosuccinate lyase
FXN57_10245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FXN57_10250	COG0753	catalase activity
FXN57_10265	COG0587	DNA-directed DNA polymerase activity
FXN57_10270	COG1022	Amp-dependent synthetase and ligase
FXN57_10285	COG1328	CTP reductase activity
FXN57_10285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FXN57_10290	COG0602	queuosine metabolic process
FXN57_10295	COG0084	hydrolase, TatD family'
FXN57_10300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FXN57_10355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FXN57_10360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FXN57_10370	COG0024	Methionine aminopeptidase
FXN57_10375	COG0316	Belongs to the HesB IscA family
FXN57_10385	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FXN57_10390	COG0672	)-iron permease
FXN57_10405	COG1136	(ABC) transporter
FXN57_10405	COG0577	efflux transmembrane transporter activity
FXN57_10415	COG1136	(ABC) transporter
FXN57_10415	COG0577	efflux transmembrane transporter activity
FXN57_10420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FXN57_10430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FXN57_10450	COG1643	Atp-dependent helicase
FXN57_10455	COG2363	Small membrane protein
FXN57_10475	COG3293	Transposase
FXN57_10480	COG0277	FAD linked oxidase domain protein
FXN57_10480	COG0247	lactate metabolic process
FXN57_10495	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FXN57_10500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FXN57_10505	COG0363	glucosamine-6-phosphate deaminase activity
FXN57_10510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FXN57_10515	COG1737	Transcriptional regulator
FXN57_10525	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FXN57_10530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FXN57_10545	COG2190	(PTS) system
FXN57_10545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FXN57_10545	COG1263	PTS System
FXN57_10585	COG3842	ATPase activity
FXN57_10590	COG1176	ABC-type spermidine putrescine transport system, permease component I
FXN57_10595	COG1177	transmembrane transport
FXN57_10600	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FXN57_10615	COG3293	Transposase
FXN57_10625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FXN57_10640	COG1522	sequence-specific DNA binding
FXN57_10650	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FXN57_10655	COG1178	ABC-type Fe3 transport system permease component
FXN57_10660	COG4143	(ABC) transporter
FXN57_10705	COG2920	part of a sulfur-relay system
FXN57_10715	COG1121	(ABC) transporter
FXN57_10720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FXN57_10725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FXN57_10740	COG1803	Methylglyoxal synthase
FXN57_10745	COG3304	Inner membrane component domain
FXN57_10750	COG1289	transmembrane transporter activity
FXN57_10765	COG3958	Transketolase
FXN57_10770	COG3959	Transketolase, thiamine diphosphate binding domain
FXN57_10810	COG3293	Transposase
FXN57_10830	COG3501	Rhs element vgr protein
FXN57_10850	COG4953	penicillin-binding protein 1C
FXN57_10855	COG3293	Transposase
FXN57_10860	COG2855	membrane
FXN57_10875	COG0157	Belongs to the NadC ModD family
FXN57_10880	COG3842	ATPase activity
FXN57_10885	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FXN57_10890	COG0725	ABC transporter, periplasmic molybdate-binding protein
FXN57_10900	COG5339	Protein conserved in bacteria
FXN57_10905	COG0443	Heat shock 70 kDa protein
FXN57_10910	COG0484	heat shock protein binding
FXN57_10915	COG2337	Toxic component of a toxin-antitoxin (TA) module
FXN57_10930	COG0626	cystathionine gamma-synthase activity
FXN57_10935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FXN57_11025	COG2337	Toxic component of a toxin-antitoxin (TA) module
FXN57_11075	COG3021	interspecies interaction between organisms
FXN57_11105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FXN57_11120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FXN57_11125	COG2999	glutathione oxidoreductase activity
FXN57_11130	COG1530	ribonuclease E activity
FXN57_11135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FXN57_11160	COG3293	Transposase
FXN57_11170	COG3293	Transposase
FXN57_11195	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN57_11200	COG1840	ABC-type Fe3 transport system, periplasmic component
FXN57_11225	COG3293	Transposase
FXN57_11235	COG2860	membrane
FXN57_11250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FXN57_11260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FXN57_11265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FXN57_11270	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FXN57_11275	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
FXN57_11300	COG2850	peptidyl-arginine hydroxylation
FXN57_11315	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FXN57_11320	COG1137	ATPase activity
FXN57_11325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FXN57_11330	COG3117	lipopolysaccharide transmembrane transporter activity
FXN57_11335	COG1127	ABC transporter
FXN57_11340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FXN57_11345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FXN57_11350	COG2854	intermembrane phospholipid transfer
FXN57_11355	COG3113	response to antibiotic
FXN57_11360	COG5007	Belongs to the BolA IbaG family
FXN57_11380	COG3293	Transposase
FXN57_11385	COG3691	Protein conserved in bacteria
FXN57_11395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FXN57_11405	COG0861	Integral membrane protein TerC family
FXN57_11430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FXN57_11435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FXN57_11455	COG0517	IMP dehydrogenase activity
FXN57_11455	COG1125	glycine betaine transport
FXN57_11460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FXN57_11470	COG0460	homoserine dehydrogenase
FXN57_11470	COG0527	aspartate kinase activity
FXN57_11485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FXN57_11490	COG2091	lysine biosynthetic process via aminoadipic acid
FXN57_11495	COG0330	HflC and HflK could
FXN57_11500	COG0330	HflC and HflK could
FXN57_11510	COG0544	peptidyl-prolyl cis-trans isomerase activity
FXN57_11515	COG4974	Belongs to the 'phage' integrase family
FXN57_11520	COG2814	Major facilitator Superfamily
FXN57_11525	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FXN57_11540	COG3266	domain, Protein
FXN57_11540	COG3061	Opacity-associated protein A
FXN57_11545	COG1509	lysine 2,3-aminomutase activity
FXN57_11555	COG3293	Transposase
FXN57_11565	COG3033	Beta-eliminating lyase
FXN57_11570	COG0814	amino acid
FXN57_11575	COG2964	Protein conserved in bacteria
FXN57_11580	COG5413	integral membrane protein
FXN57_11590	COG0204	Acyl-transferase
FXN57_11600	COG0697	spore germination
FXN57_11605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FXN57_11610	COG1882	Formate acetyltransferase
FXN57_11615	COG2116	formate transmembrane transporter activity
FXN57_11620	COG3293	Transposase
FXN57_11625	COG0537	adenosine 5'-monophosphoramidase activity
FXN57_11645	COG0205	6-phosphofructokinase activity
FXN57_11660	COG3022	response to hydroperoxide
FXN57_11665	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FXN57_11680	COG0681	Belongs to the peptidase S26 family
FXN57_11715	COG0230	Belongs to the bacterial ribosomal protein bL34 family