locus-tag	class	description
ACT74_00010	ENOG4105DQ6	Transposase
ACT74_00020	ENOG4105M5K	heptosyltransferase
ACT74_00025	ENOG4108IJ0	Aspartate ammonia-lyase
ACT74_00035	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ACT74_00040	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ACT74_00045	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ACT74_00060	ENOG4105DQ6	Transposase
ACT74_00070	ENOG41080IJ	Diacylglycerol kinase
ACT74_00075	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACT74_00080	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ACT74_00085	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
ACT74_00090	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ACT74_00105	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
ACT74_00110	ENOG4105DSJ	YicC domain protein
ACT74_00115	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
ACT74_00120	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ACT74_00125	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
ACT74_00140	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT74_00145	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
ACT74_00150	ENOG4107QKW	extracellular solute-binding protein family 1
ACT74_00155	ENOG41090ED	Protein with unknown function (DUF469)
ACT74_00160	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ACT74_00165	ENOG4105CEN	a g-specific adenine glycosylase
ACT74_00170	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
ACT74_00175	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
ACT74_00190	ENOG4105IEY	(LipO)protein
ACT74_00195	ENOG4105M85	Bola protein
ACT74_00210	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACT74_00215	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACT74_00220	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ACT74_00225	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
ACT74_00230	ENOG4105CJ2	(LipO)protein
ACT74_00240	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ACT74_00245	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ACT74_00250	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ACT74_00255	ENOG4108UJU	UPF0301 protein
ACT74_00260	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
ACT74_00265	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
ACT74_00270	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
ACT74_00275	ENOG4107QKV	phosphomannomutase
ACT74_00280	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
ACT74_00285	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ACT74_00290	ENOG4108M6U	Universal stress protein A
ACT74_00295	ENOG4105DXN	mazG family
ACT74_00305	ENOG4105E68	Sulfatase
ACT74_00310	ENOG4105YDX	UPF0352 protein
ACT74_00320	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
ACT74_00325	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
ACT74_00330	ENOG4105E0F	Histidine kinase
ACT74_00335	ENOG4105D6U	Sodium Glutamate Symporter
ACT74_00345	ENOG4107S2Z	UPF0761 membrane protein
ACT74_00350	ENOG4105K5B	UPF0225 protein
ACT74_00360	ENOG4105D7A	ATP-binding protein
ACT74_00370	ENOG4105EQ2	LysR family Transcriptional regulator
ACT74_00380	ENOG4105CPC	Aldo Keto reductase
ACT74_00385	ENOG4105EBR	Carboxylesterase
ACT74_00400	ENOG4105EQ2	LysR family Transcriptional regulator
ACT74_00405	ENOG4105ENX	hydrolase
ACT74_00410	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ACT74_00415	ENOG410804X	Transcriptional regulator
ACT74_00420	ENOG4105K70	DNA-binding protein
ACT74_00425	ENOG4105R2J	Conserved Protein
ACT74_00430	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ACT74_00450	ENOG4105C9X	ppx gppa phosphatase
ACT74_00455	ENOG4105MA0	exported protein
ACT74_00460	ENOG4105CFU	surface antigen
ACT74_00465	ENOG4105WH1	Two component transcriptional regulator luxr family
ACT74_00470	ENOG4107T0K	Adenylate cyclase
ACT74_00475	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ACT74_00485	ENOG4105ECF	c-methyltransferase
ACT74_00490	ENOG410601J	HemY protein
ACT74_00495	ENOG4105EX9	Membrane
ACT74_00505	ENOG4108WQI	RNA Polymerase
ACT74_00515	ENOG4108RRZ	Transcription elongation factor GreB
ACT74_00520	ENOG4108TGR	phosphatase
ACT74_00525	ENOG4107QPK	)-transporter
ACT74_00535	ENOG4105BZM	domain protein
ACT74_00540	ENOG4105CMG	Carbohydrate kinase
ACT74_00545	ENOG4105CNN	ABC, transporter
ACT74_00550	ENOG4105C2J	ABC transporter
ACT74_00555	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
ACT74_00560	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACT74_00585	ENOG4105CS9	pantothenic acid kinase
ACT74_00590	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT74_00595	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ACT74_00600	ENOG4105XQ6	frataxin-like protein
ACT74_00605	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ACT74_00610	ENOG4105R3P	Inner membrane protein yagU
ACT74_00615	ENOG4108R3E	Dna-3-methyladenine glycosylase i
ACT74_00620	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
ACT74_00630	ENOG4105CIN	aminoacyl-histidine dipeptidase
ACT74_00635	ENOG4108IXY	short-chain dehydrogenase reductase
ACT74_00640	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
ACT74_00645	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
ACT74_00650	ENOG4105VQK	sigma E regulatory protein, MucB RseB
ACT74_00655	ENOG41069PW	sigma-e factor negative regulatory protein
ACT74_00660	ENOG4105EMN	RNA polymerase sigma factor
ACT74_00665	ENOG4105Y75	tpr repeat protein
ACT74_00675	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ACT74_00680	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ACT74_00685	ENOG4105EM7	Selenocysteine-specific translation elongation factor
ACT74_00700	ENOG4108R99	pseudouridine synthase
ACT74_00705	ENOG4105C8J	)-transporter
ACT74_00795	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ACT74_00810	ENOG4108JA2	transcriptioN-repair coupling factor
ACT74_00820	ENOG4105E5Z	arginine transporter ATP-binding subunit
ACT74_00825	ENOG4106PMH	Extracellular solute-binding protein family 3
ACT74_00830	ENOG4105GBT	ABC transporter
ACT74_00835	ENOG4105DMR	ABC, transporter
ACT74_00845	ENOG4108V6E	Cell division protein mraZ
ACT74_00850	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ACT74_00860	ENOG4105CJN	penicillin-binding protein
ACT74_00865	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ACT74_00870	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
ACT74_00875	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ACT74_00880	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ACT74_00885	ENOG4105CNI	cell division protein FtsW
ACT74_00890	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
ACT74_00895	ENOG4105DFU	Cell wall formation (By similarity)
ACT74_00900	ENOG4105CPF	Cell wall formation (By similarity)
ACT74_00905	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
ACT74_00910	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ACT74_00915	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ACT74_00925	ENOG4105CQC	Prephenate dehydratase
ACT74_00930	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ACT74_00935	ENOG4105KUZ	arsenate reductase
ACT74_00950	ENOG41087AY	ADP-Ribose pyrophosphatase
ACT74_00955	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
ACT74_00970	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ACT74_00985	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
ACT74_00990	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
ACT74_00995	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
ACT74_01000	ENOG4105E33	succinate dehydrogenase
ACT74_01005	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
ACT74_01010	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
ACT74_01015	ENOG4105E0A	ABC, transporter
ACT74_01020	ENOG4108IHU	transport system permease protein
ACT74_01025	ENOG4105DQ5	transport system permease protein
ACT74_01030	ENOG4108HUF	Transporter
ACT74_01035	ENOG4105DIN	metallophosphoesterase
ACT74_01040	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ACT74_01045	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ACT74_01050	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ACT74_01070	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
ACT74_01075	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
ACT74_01080	ENOG4107SC1	transglycosylase
ACT74_01085	ENOG4105K9H	YciI-like protein
ACT74_01090	ENOG4105NAU	thioesterase Superfamily protein
ACT74_01095	ENOG4107835	probably involved in intracellular septation (By similarity)
ACT74_01105	ENOG4105EIF	outer membrane protein W
ACT74_01110	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ACT74_01120	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACT74_01130	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ACT74_01135	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACT74_01140	ENOG4105BZU	Histidine kinase
ACT74_01145	ENOG4108HWV	)-transporter
ACT74_01155	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
ACT74_01160	ENOG41060NJ	transcriptional regulator
ACT74_01165	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
ACT74_01170	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
ACT74_01175	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
ACT74_01190	ENOG4107QPK	)-transporter
ACT74_01195	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
ACT74_01200	ENOG4105CHY	citrate lyase, alpha
ACT74_01205	ENOG4105CI0	Citrate lyase
ACT74_01215	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
ACT74_01220	ENOG4108JU5	Magnesium and cobalt efflux protein
ACT74_01225	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ACT74_01235	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ACT74_01240	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ACT74_01245	ENOG4105E2D	ec 3.2.1.52
ACT74_01250	ENOG4105D1F	ATP-binding protein
ACT74_01255	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ACT74_01260	ENOG4105WVQ	Fe-S assembly protein IscX
ACT74_01265	ENOG4108ZIT	Ferredoxin, 2FE-2S
ACT74_01270	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
ACT74_01275	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
ACT74_01280	ENOG4108Z4V	iron-sulfur cluster assembly
ACT74_01285	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
ACT74_01295	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
ACT74_01300	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
ACT74_01305	ENOG4105ECY	inositol monophosphatase
ACT74_01315	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT74_01320	ENOG4107RCV	ABC transporter, permease
ACT74_01325	ENOG4105C4Y	ABC transporter
ACT74_01330	ENOG4105C4Y	ABC transporter
ACT74_01350	ENOG4105F27	Major Facilitator
ACT74_01355	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ACT74_01370	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ACT74_01380	ENOG4105CK7	Sodium proline symporter
ACT74_01385	ENOG4105C03	ribonuclease
ACT74_01390	ENOG4105E9S	glutaredoxin 2
ACT74_01395	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
ACT74_01445	ENOG4106BMH	cytolethal distending toxin
ACT74_01450	ENOG4108TMH	cytolethal distending toxin
ACT74_01490	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
ACT74_01495	ENOG4105C28	cystathionine
ACT74_01515	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ACT74_01520	ENOG4105CFG	Acts as a chaperone (By similarity)
ACT74_01525	ENOG4106J39	exported protein
ACT74_01535	ENOG4105NBI	YecM protein
ACT74_01540	ENOG4108XTF	Outer Membrane Lipoprotein
ACT74_01545	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ACT74_01550	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ACT74_01555	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ACT74_01560	ENOG4107TT5	NLP P60 protein
ACT74_01570	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
ACT74_01580	ENOG4108BY2	phosphohistidine phosphatase
ACT74_01590	ENOG4105EEI	dihydropteroate synthase
ACT74_01595	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ACT74_01615	ENOG4105IYK	transposase
ACT74_01620	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ACT74_01625	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
ACT74_01660	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
ACT74_01665	ENOG4108EU3	peptide transport system, permease
ACT74_01675	ENOG4108EVY	peptide transport periplasmic protein
ACT74_01680	ENOG4105CM6	amino acid regulated cytosolic protein
ACT74_01685	ENOG4106K28	UPF0283 membrane protein
ACT74_01690	ENOG4108JU8	Transcriptional regulator
ACT74_01695	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
ACT74_01705	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
ACT74_01710	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ACT74_01715	ENOG4105K8N	protein family UPF0079, ATPase
ACT74_01725	ENOG4105IHM	Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane (By similarity)
ACT74_01730	ENOG410838F	Glycosyl transferase family 2
ACT74_01735	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
ACT74_01745	ENOG4108I6E	Sulfatase
ACT74_01765	ENOG4105KZ7	phosphocarrier protein hpr
ACT74_01770	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
ACT74_01775	ENOG4105C5Y	PTS System
ACT74_01780	ENOG4105DGW	oligopeptidase A
ACT74_01785	ENOG4105WD1	Membrane
ACT74_01790	ENOG4107TSG	Extracellular solute-binding protein, family 5
ACT74_01800	ENOG4105CRQ	synthase (Component I)
ACT74_01805	ENOG4105DDQ	anthranilate synthase
ACT74_01810	ENOG4105C5I	Dehydrogenase
ACT74_01815	ENOG4105D60	lipoprotein releasing system transmembrane protein
ACT74_01820	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
ACT74_01825	ENOG4105D60	lipoprotein releasing system transmembrane protein
ACT74_01830	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
ACT74_01835	ENOG4105CDU	Replicative dna helicase
ACT74_01840	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ACT74_01845	ENOG4107QP8	phosphohexose isomerase
ACT74_01850	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ACT74_01860	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ACT74_01865	ENOG4108ZAI	phosphatidylglycerophosphatase a
ACT74_01870	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
ACT74_01880	ENOG4105XPH	Ferredoxin
ACT74_01890	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACT74_01900	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACT74_01910	ENOG4105C4Y	ABC transporter
ACT74_01915	ENOG4107RCV	ABC transporter, permease
ACT74_01920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT74_01925	ENOG4107T9C	Alpha amylase catalytic region
ACT74_01930	ENOG4105EG2	ABC transporter, permease
ACT74_01935	ENOG4105D56	permease protein
ACT74_01940	ENOG4107FKK	extracellular solute-binding protein family 1
ACT74_01945	ENOG4108IJ9	(ABC) transporter
ACT74_01950	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
ACT74_01955	ENOG4107W52	maltose operon periplasmic protein
ACT74_01960	ENOG4105D06	uba thif-type nad fad binding protein
ACT74_01965	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
ACT74_01970	ENOG4105EUJ	GTP cyclohydrolase i
ACT74_01975	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
ACT74_01980	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ACT74_01985	ENOG4105HBR	Rna-binding protein
ACT74_01990	ENOG4105VUH	addiction module killer protein
ACT74_01995	ENOG4105YES	addiction module antidote protein
ACT74_02000	ENOG4108R6K	riboflavin synthase, subunit alpha
ACT74_02005	ENOG4107QI1	Mate efflux family protein
ACT74_02010	ENOG4108Z66	YbaK ebsC protein
ACT74_02015	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACT74_02030	ENOG4108VEN	abc transporter atp-binding protein
ACT74_02035	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ACT74_02040	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
ACT74_02045	ENOG4105DN3	alpha-2-macroglobulin domain protein
ACT74_02050	ENOG4105HMI	Membrane
ACT74_02055	ENOG4108JQB	penicillin-binding protein 1C
ACT74_02080	ENOG4105DW5	Transcriptional regulator
ACT74_02085	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
ACT74_02090	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
ACT74_02095	ENOG4105E0U	tyrosine-specific transport protein
ACT74_02100	ENOG4105CNT	hydrolase family 2
ACT74_02105	ENOG41090BQ	Glutaredoxin
ACT74_02110	ENOG4108DBC	nitroreductase
ACT74_02120	ENOG4105RHG	
ACT74_02125	ENOG4105C9Q	fumarate hydratase class II
ACT74_02130	ENOG4105MYG	DNA polymerase iii, chi subunit
ACT74_02160	ENOG4105CAF	HipA N-terminal domain protein
ACT74_02170	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ACT74_02175	ENOG4105CW7	secretion protein, HlyD family
ACT74_02180	ENOG4108RMU	ferritin dps family protein
ACT74_02190	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ACT74_02195	ENOG4107QNR	UPF0135 protein
ACT74_02200	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ACT74_02205	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
ACT74_02210	ENOG4105CRK	lysyL-tRNA synthetase
ACT74_02220	ENOG4105T95	Thiol disulfide interChange protein
ACT74_02225	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ACT74_02235	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
ACT74_02240	ENOG4105UZ0	ABC-type Co2 transport system, periplasmic component
ACT74_02245	ENOG4108A51	
ACT74_02250	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
ACT74_02260	ENOG4108JJB	ABC transporter
ACT74_02270	ENOG4105CQS	hydrogenase expression formation protein HypD
ACT74_02275	ENOG4105C45	hydrogenase expression formation protein (HypE)
ACT74_02290	ENOG4105F9E	Shikimate 5-dehydrogenase
ACT74_02295	ENOG4105SYT	Methylenetetrahydrofolate reductase
ACT74_02300	ENOG4108K5H	permease YjgP YjgQ family protein
ACT74_02305	ENOG4108M8S	permease YjgP YjgQ family protein
ACT74_02310	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
ACT74_02315	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
ACT74_02320	ENOG4105E0C	molybdate abc transporter
ACT74_02325	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ACT74_02330	ENOG4105F4R	Transcriptional regulator mode
ACT74_02335	ENOG4105C8P	)-transporter
ACT74_02340	ENOG4105DK2	UPF0207 protein
ACT74_02345	ENOG4105C0H	protease
ACT74_02350	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ACT74_02355	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
ACT74_02360	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
ACT74_02365	ENOG4105ETT	transcriptional Regulator, LysR family
ACT74_02370	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ACT74_02380	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
ACT74_02385	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
ACT74_02390	ENOG4105ECP	epimerase
ACT74_02395	ENOG4105DGN	Electron transport complex
ACT74_02400	ENOG4108R3D	Electron transport complex
ACT74_02405	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
ACT74_02420	ENOG4105DZB	Electron transport complex
ACT74_02425	ENOG4105CSM	endonuclease III
ACT74_02430	ENOG4105C8J	)-transporter
ACT74_02435	ENOG4105FAV	ABC, transporter
ACT74_02440	ENOG4105FDK	ABC transporter
ACT74_02445	ENOG4105DR5	peptidase
ACT74_02450	ENOG4108IPW	abc transporter atp-binding protein
ACT74_02455	ENOG4105CM4	permease protein
ACT74_02460	ENOG4105DHS	permease protein
ACT74_02470	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
ACT74_02480	ENOG4105H4F	exported protein
ACT74_02505	ENOG4107H6E	
ACT74_02515	ENOG4105DHQ	Histidine kinase
ACT74_02520	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ACT74_02525	ENOG4106CC8	Bacterial inner membrane protein
ACT74_02530	ENOG4105CDH	Citrulline--aspartate ligase
ACT74_02535	ENOG4108535	NAD dependent epimerase/dehydratase family
ACT74_02540	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
ACT74_02545	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
ACT74_02555	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
ACT74_02580	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ACT74_02585	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
ACT74_02600	ENOG4105DP9	ABC transporter
ACT74_02605	ENOG4106SMU	thiamine transporter membrane protein
ACT74_02610	ENOG4107T0D	ABC, transporter
ACT74_02620	ENOG4105C0H	protease
ACT74_02625	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
ACT74_02630	ENOG4105DDY	UPF0142 protein ycaO
ACT74_02635	ENOG4105EIP	mannose-6-phosphate isomerase
ACT74_02640	ENOG4105KWI	UPF0339 protein
ACT74_02655	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ACT74_02665	ENOG4105E2R	ROK family
ACT74_02690	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ACT74_02695	ENOG4105EYM	Major Facilitator superfamily
ACT74_02700	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
ACT74_02705	ENOG4105CMR	udp-glucose 4-epimerase
ACT74_02710	ENOG4105KAF	membrAne
ACT74_02715	ENOG4105C7N	Xanthine uracil vitamin C permease
ACT74_02720	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
ACT74_02725	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
ACT74_02730	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ACT74_02735	ENOG4105VT2	5-hydroxyisourate hydrolase
ACT74_02765	ENOG410682P	Hypothetical protein (DUF2513)
ACT74_02795	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
ACT74_02835	ENOG4105CEE	C4-dicarboxylate transporter
ACT74_02845	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
ACT74_02850	ENOG4105CHV	Transcription elongation factor NusA
ACT74_02855	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ACT74_02860	ENOG4107QMH	DNA methylase
ACT74_02875	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ACT74_02890	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ACT74_02900	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
ACT74_02905	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
ACT74_02920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT74_02940	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ACT74_02950	ENOG41085JB	UPF0434 protein
ACT74_02955	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ACT74_02965	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
ACT74_02970	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
ACT74_02975	ENOG4105DJ0	Poly(A) Polymerase
ACT74_02980	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACT74_02990	ENOG4108DNC	Involved in acetate metabolism (By similarity)
ACT74_02995	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ACT74_03000	ENOG4105PQ6	UPF0208 membrane protein
ACT74_03005	ENOG4105E96	Colicin v production protein
ACT74_03010	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
ACT74_03015	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
ACT74_03020	ENOG41061ZR	Transcriptional regulator
ACT74_03030	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
ACT74_03035	ENOG4107QSN	dihydrolipoamide acetyltransferase
ACT74_03040	ENOG4107QN2	dihydrolipoyl dehydrogenase
ACT74_03045	ENOG41069NU	Nitroreductase
ACT74_03050	ENOG4105D07	Signal peptide peptidase, SppA
ACT74_03055	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
ACT74_03060	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
ACT74_03065	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
ACT74_03070	ENOG4105FE9	pseudouridine synthase
ACT74_03075	ENOG4107R11	Transcriptional regulator
ACT74_03080	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
ACT74_03085	ENOG4105XW2	UPF0263 protein
ACT74_03090	ENOG4105ETE	Transcriptional regulator (LacI family
ACT74_03095	ENOG4105DWV	Homoserine O-trans-acetylase
ACT74_03100	ENOG4107GZ4	SanA protein
ACT74_03105	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
ACT74_03120	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACT74_03125	ENOG4107QIV	Cytochrome c biogenesis protein
ACT74_03130	ENOG4105E0X	reductase
ACT74_03135	ENOG41077A9	carbonic anhydrase
ACT74_03140	ENOG4105W4M	Transport-associated protein
ACT74_03145	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
ACT74_03150	ENOG41082RQ	UPF0102 protein
ACT74_03155	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
ACT74_03160	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
ACT74_03170	ENOG4105CEP	NADH dehydrogenase
ACT74_03180	ENOG4105ERU	peptidase
ACT74_03190	ENOG4105FGM	Fructosamine kinase
ACT74_03195	ENOG4105C22	threonyL-tRNA synthetase
ACT74_03215	ENOG4105DP0	ferredoxin-NADP reductase
ACT74_03220	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ACT74_03225	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ACT74_03230	ENOG4105D2M	Aldolase
ACT74_03235	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
ACT74_03240	ENOG41082GB	PTS system galactitol-specific transporter subunit IIA
ACT74_03245	ENOG41090UW	PTS System
ACT74_03250	ENOG4105DT3	PTS system, galactitol-specific IIc component
ACT74_03260	ENOG4105E98	transcriptional regulator DeoR family
ACT74_03265	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ACT74_03270	ENOG4105CTB	Polyprenyl synthetase
ACT74_03275	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
ACT74_03280	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ACT74_03285	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ACT74_03290	ENOG4108TGR	phosphatase
ACT74_03295	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
ACT74_03300	ENOG4105DWU	Membrane
ACT74_03305	ENOG4108W1A	pseudouridine synthase
ACT74_03315	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ACT74_03345	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ACT74_03355	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ACT74_03365	ENOG4108ZZ3	UPF0260 protein
ACT74_03375	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ACT74_03380	ENOG4108ESZ	Glycogen debranching enzyme
ACT74_03390	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ACT74_03395	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
ACT74_03400	ENOG4108VD1	dedA family
ACT74_03405	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ACT74_03415	ENOG41061WM	D-Alanyl-D-Alanine
ACT74_03420	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
ACT74_03425	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT74_03430	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
ACT74_03435	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
ACT74_03440	ENOG4108TZV	Membrane
ACT74_03445	ENOG4105CJB	Exodeoxyribonuclease I
ACT74_03455	ENOG4105DQ6	Transposase
ACT74_03470	ENOG41090A1	ferritin
ACT74_03475	ENOG41090A1	ferritin
ACT74_03480	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
ACT74_03485	ENOG4105Q9Y	Universal stress protein
ACT74_03495	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ACT74_03500	ENOG4105DB7	PHP domain protein
ACT74_03505	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ACT74_03510	ENOG4105CD8	aminopeptidase N
ACT74_03515	ENOG4105CGF	Aromatic amino acid aminotransferase
ACT74_03525	ENOG4105D0S	secretion protein (HlyD
ACT74_03530	ENOG4105CJ1	ABC, transporter
ACT74_03535	ENOG4105CMI	transporter
ACT74_03545	ENOG4105EHG	Permease protein
ACT74_03550	ENOG4105E0A	ABC, transporter
ACT74_03560	ENOG4107RNH	Outer membrane receptor FepA
ACT74_03565	ENOG4105E0A	ABC, transporter
ACT74_03570	ENOG4105EHG	Permease protein
ACT74_03575	ENOG4105S10	periplasmic binding protein
ACT74_03580	ENOG4106ZKY	
ACT74_03600	ENOG4108QBX	(LipO)protein
ACT74_03605	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ACT74_03610	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
ACT74_03615	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ACT74_03620	ENOG4105D0M	Protease HtpX homolog
ACT74_03625	ENOG4105C2X	Arabinose 5-phosphate isomerase
ACT74_03630	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
ACT74_03635	ENOG4105CRQ	synthase (Component I)
ACT74_03640	ENOG4105DDQ	anthranilate synthase
ACT74_03645	ENOG4108V5Q	transglutaminase-like protein
ACT74_03650	ENOG4107QYG	anthranilate phosphoribosyltransferase
ACT74_03660	ENOG41082AG	Plasmid maintenance system antidote protein
ACT74_03665	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ACT74_03680	ENOG4106AFN	Lyase and sodium transporter (By similarity)
ACT74_03685	ENOG4107QSA	Oxaloacetate decarboxylase
ACT74_03690	ENOG4105D9Q	decarboxylase (Beta subunit)
ACT74_03695	ENOG4108MVK	Receptor
ACT74_03705	ENOG4105EMU	Dehydrogenase
ACT74_03710	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ACT74_03720	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ACT74_03730	ENOG4105CA9	Pyruvate kinase
ACT74_03740	ENOG41061GT	Aldolase
ACT74_03745	ENOG4105D4B	ABC, transporter
ACT74_03760	ENOG4105C2J	ABC transporter
ACT74_03765	ENOG4105DKT	Transcriptional regulator
ACT74_03775	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ACT74_03780	ENOG4105DAG	ROK family
ACT74_03785	ENOG4105C5S	asparaginyl-tRNA synthetase
ACT74_03790	ENOG4105KB2	stringent starvation protein b
ACT74_03795	ENOG4107MKT	Stringent starvation protein a
ACT74_03800	ENOG4108ZAF	Molybdopterin
ACT74_03805	ENOG4105M00	molybdopterin converting factor, subunit 1
ACT74_03815	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ACT74_03820	ENOG4105CHW	UPF0052 protein
ACT74_03830	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
ACT74_03835	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
ACT74_03840	ENOG4105CUW	cytochrome C-TYPE protein
ACT74_03845	ENOG4107QY8	reductase
ACT74_03850	ENOG4105UNS	Pfam:DUF419
ACT74_03855	ENOG4107QPK	)-transporter
ACT74_03870	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ACT74_03890	ENOG4107QYX	exodeoxyribonuclease v alpha
ACT74_03895	ENOG4107QKA	exodeoxyribonuclease V beta
ACT74_03900	ENOG41090EX	DsrE family
ACT74_03910	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
ACT74_03915	ENOG4105DAN	ATP-dependent protease
ACT74_03920	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
ACT74_03925	ENOG4105VEQ	Cold shock protein
ACT74_03930	ENOG4105X5C	UPF0181 protein
ACT74_03935	ENOG4105DR9	pseudouridine synthase
ACT74_03940	ENOG4105WP7	tRNA pseudouridine synthase C
ACT74_03945	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
ACT74_03950	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
ACT74_03965	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
ACT74_03985	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ACT74_03990	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
ACT74_03995	ENOG4105CIY	formyltetrahydrofolate deformylase
ACT74_04000	ENOG4108SAU	DNA-binding protein H-ns
ACT74_04005	ENOG4107S6Z	Na H antiporter
ACT74_04035	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ACT74_04040	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
ACT74_04045	ENOG4105CB5	ATP-dependent DNA helicase recG
ACT74_04050	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ACT74_04055	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
ACT74_04060	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ACT74_04065	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ACT74_04075	ENOG4108Z1B	Cyclase dehydrase
ACT74_04080	ENOG4105VDB	UPF0125 protein
ACT74_04085	ENOG4105EZE	Cupin 4 family protein
ACT74_04095	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
ACT74_04100	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
ACT74_04105	ENOG4108IUZ	ABC transporter
ACT74_04110	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
ACT74_04115	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
ACT74_04120	ENOG4105DHJ	ABC, transporter
ACT74_04125	ENOG4105CY3	ABC transporter, permease
ACT74_04130	ENOG4107PE3	Mammalian cell entry related domain protein
ACT74_04135	ENOG4105E3I	toluene tolerance
ACT74_04145	ENOG4105VFK	BolA family
ACT74_04150	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ACT74_04165	ENOG4107R0E	Glycosyl transferase, family 2
ACT74_04175	ENOG4105KZW	UPF0381 protein
ACT74_04180	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
ACT74_04185	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ACT74_04195	ENOG4105EE5	Membrane protein terC
ACT74_04205	ENOG4105DQ6	Transposase
ACT74_04210	ENOG4105C5F	glutamine synthetase
ACT74_04215	ENOG4105CI3	gtp-binding protein typa
ACT74_04225	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACT74_04230	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACT74_04245	ENOG4108IJ8	ABC transporter
ACT74_04250	ENOG4105DFA	alanine racemase domain protein
ACT74_04260	ENOG4105CFH	Aspartokinase
ACT74_04275	ENOG4105D98	threonine synthase
ACT74_04285	ENOG4107QJR	hflk protein
ACT74_04290	ENOG4105EPW	hflc protein
ACT74_04295	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
ACT74_04300	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ACT74_04305	ENOG4105K8R	UPF0145 protein
ACT74_04310	ENOG4105CSA	Coproporphyrinogen iii oxidase
ACT74_04315	ENOG4105E66	phosphoriboisomerase A
ACT74_04320	ENOG4108JQ1	Dehydrogenase
ACT74_04325	ENOG4105S10	periplasmic binding protein
ACT74_04330	ENOG4108UHU	Aldolase
ACT74_04340	ENOG4105DMW	Dehydrogenase reductase
ACT74_04345	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
ACT74_04350	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ACT74_04355	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
ACT74_04360	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ACT74_04370	ENOG4107YCY	Transcriptional regulator
ACT74_04390	ENOG4105CHH	sulfate transporter
ACT74_04400	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ACT74_04405	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACT74_04410	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ACT74_04415	ENOG4105VCC	30S ribosomal protein S21
ACT74_04420	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACT74_04430	ENOG4107104	thymidine kinase
ACT74_04440	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
ACT74_04445	ENOG4105EXN	Sulfate transport protein CysZ
ACT74_04450	ENOG4105C6T	cysteine synthase
ACT74_04455	ENOG4108RG0	uracil-dna glycosylase
ACT74_04460	ENOG4105C3G	gtp-binding protein
ACT74_04465	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ACT74_04525	ENOG4105ESV	Glycosyl transferase, family 4
ACT74_04530	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ACT74_04535	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
ACT74_04540	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
ACT74_04545	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
ACT74_04555	ENOG4105BZ4	penicillin-binding protein
ACT74_04560	ENOG4107SJW	iron permease, FTR1
ACT74_04575	ENOG4107RBB	ABC transporter, permease
ACT74_04585	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ACT74_04590	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACT74_04600	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACT74_04620	ENOG4105CQ7	ATP-dependent helicase
ACT74_04625	ENOG4105M08	Membrane
ACT74_04630	ENOG4108VMM	UPF0756 membrane protein
ACT74_04635	ENOG4105M2J	Glutaredoxin
ACT74_04645	ENOG4105CQB	FAD linked oxidase domain protein
ACT74_04650	ENOG4105KA0	thioesterase Superfamily protein
ACT74_04660	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ACT74_04665	ENOG4105CE4	GlcNAc 6-P deacetylase
ACT74_04670	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
ACT74_04675	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ACT74_04680	ENOG4105QEK	Transcriptional regulator
ACT74_04690	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
ACT74_04695	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
ACT74_04700	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ACT74_04705	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
ACT74_04710	ENOG4105CI1	PTS System
ACT74_04730	ENOG4105D7X	high-affinity nickel-transporter
ACT74_04735	ENOG41065CD	Exported protein
ACT74_04740	ENOG4105C5H	ABC transporter
ACT74_04750	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT74_04755	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT74_04760	ENOG4108K3A	Glutathione S-transferase
ACT74_04770	ENOG4108VTV	Inherit from NOG: Membrane
ACT74_04775	ENOG4105M4H	endoribonuclease L-psp
ACT74_04795	ENOG4107QMP	dna polymerase iii subunits gamma and tau
ACT74_04805	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
ACT74_04810	ENOG4105EJ9	Membrane
ACT74_04815	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
ACT74_04820	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ACT74_04825	ENOG4105EGS	Mechanosensitive ion channel
ACT74_04830	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT74_04835	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
ACT74_04840	ENOG4105EV9	Alpha Beta Hydrolase
ACT74_04845	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
ACT74_04850	ENOG41090R7	Ferric uptake
ACT74_04855	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ACT74_04865	ENOG4108ZJT	translation initiation factor, Sui1
ACT74_04875	ENOG4105CFV	Tetratricopeptide repeat protein
ACT74_04880	ENOG4105Q4A	inner membrane protein yciS
ACT74_04885	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
ACT74_04890	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ACT74_04895	ENOG4105CAT	Cytidine monophosphate kinase
ACT74_04900	ENOG4108MJ5	VirK protein
ACT74_04910	ENOG4107RAN	Peptidase, M16
ACT74_04915	ENOG4105KMT	branched-chain amino acid
ACT74_04920	ENOG4108UMN	azlc family
ACT74_04925	ENOG4105DZ2	Transcriptional regulator
ACT74_04930	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
ACT74_04950	ENOG4108MN8	Membrane
ACT74_04955	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
ACT74_04965	ENOG4105DIK	(ABC) transporter
ACT74_04970	ENOG4105CC5	ABC transporter
ACT74_04975	ENOG4105CC5	ABC transporter
ACT74_04980	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
ACT74_04985	ENOG41068P6	UPF0319 protein
ACT74_04990	ENOG4108Z5K	methylglyoxal synthase
ACT74_04995	ENOG410901E	Membrane
ACT74_05000	ENOG4105EM2	membrane
ACT74_05005	ENOG4108DG9	Smr protein MutS2
ACT74_05010	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
ACT74_05015	ENOG4108IUS	Transketolase
ACT74_05045	ENOG4105C5H	ABC transporter
ACT74_05050	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
ACT74_05055	ENOG41067MG	lrgb family
ACT74_05060	ENOG4105VAW	lrga family
ACT74_05070	ENOG4105KK6	nuclease
ACT74_05075	ENOG4105C9B	Cysteine desulfurase
ACT74_05080	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ACT74_05085	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
ACT74_05090	ENOG4105D1S	lipid A biosynthesis
ACT74_05095	ENOG4107XHZ	cytoplasmic chaperone TorD family protein
ACT74_05100	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
ACT74_05110	ENOG4107QX8	SPFH domain, Band 7 family protein
ACT74_05135	ENOG4105CA0	peroxidase
ACT74_05140	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
ACT74_05145	ENOG4105CEY	Amp-dependent synthetase and ligase
ACT74_05150	ENOG4105R8X	Outer membrane lipoprotein Slp
ACT74_05155	ENOG41072GX	Peptidase M22 Glycoprotease
ACT74_05160	ENOG4105DVT	helicase
ACT74_05165	ENOG4105DSB	aldose 1-epimerase
ACT74_05170	ENOG4107QR8	Thioredoxin
ACT74_05175	ENOG4105C3M	thioredoxin reductase
ACT74_05180	ENOG4108JJ9	ABC, transporter
ACT74_05185	ENOG4108JJ8	(ABC) transporter
ACT74_05190	ENOG4105C29	acyl-CoA thioesterase
ACT74_05195	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
ACT74_05205	ENOG4105F3T	(LipO)protein
ACT74_05210	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
ACT74_05215	ENOG4105EYK	Phosphatidylglycerophosphatase B
ACT74_05220	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
ACT74_05235	ENOG4105GXY	Family of unknown function (DUF695) 
ACT74_05240	ENOG4105CGK	Exodeoxyribonuclease III
ACT74_05245	ENOG4105D3Q	Sugar transferase
ACT74_05250	ENOG4108KBE	Glycosyl transferase, family 2
ACT74_05255	ENOG4108RT7	Glycosyl transferase, family 2
ACT74_05265	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
ACT74_05270	ENOG4105WH5	Teichoic acid glycosylation protein
ACT74_05290	ENOG4105K64	Glycosyl transferase, family 2
ACT74_05300	ENOG4105MFV	ABC-2 type transporter
ACT74_05305	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ACT74_05315	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ACT74_05320	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
ACT74_05325	ENOG4105CVE	Lytic murein transglycosylase
ACT74_05330	ENOG4108RYC	glycosyltransferase
ACT74_05335	ENOG4108RJ9	Glycosyl transferase, family 2
ACT74_05345	ENOG41068D6	Glycosyltransferase
ACT74_05355	ENOG4108ZPC	Polysaccharide pyruvyl transferase
ACT74_05365	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ACT74_05370	ENOG41080C8	DUF218 domain
ACT74_05380	ENOG4105C4R	Atp-dependent dna helicase
ACT74_05385	ENOG4105C6Z	Gluconate
ACT74_05390	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
ACT74_05395	ENOG4105DIQ	Transcriptional regulator
ACT74_05400	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
ACT74_05415	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ACT74_05420	ENOG4108MG3	formate dehydrogenase
ACT74_05425	ENOG4105C8H	hydrogenase maturation protein Hypf
ACT74_05430	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
ACT74_05435	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACT74_05440	ENOG4107TDF	Formate hydrogenlyase subunit 4
ACT74_05445	ENOG4105D65	subunit l
ACT74_05450	ENOG4107WQX	hydrogenase 4 membrane subunit
ACT74_05455	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ACT74_05460	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
ACT74_05470	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
ACT74_05475	ENOG4105I6X	formate hydrogenlyase maturation
ACT74_05480	ENOG4108MG9	hydrogenase 3 maturation protease
ACT74_05485	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ACT74_05490	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
ACT74_05495	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
ACT74_05500	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
ACT74_05505	ENOG4105C7S	Dehydrogenase
ACT74_05510	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
ACT74_05515	ENOG4105C5X	domain protein
ACT74_05520	ENOG4105EAQ	(twin-arginine translocation) pathway signal
ACT74_05525	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
ACT74_05530	ENOG4105CN1	protease
ACT74_05535	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
ACT74_05540	ENOG4105H2K	paraquat-inducible protein a
ACT74_05545	ENOG4105DY2	Paraquat-inducible protein b
ACT74_05550	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
ACT74_05555	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ACT74_05560	ENOG4105F38	ABC transporter, permease
ACT74_05565	ENOG4105D38	putrescine abc transporter
ACT74_05570	ENOG4107RUE	extracellular solute-binding protein family 1
ACT74_05575	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
ACT74_05585	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
ACT74_05590	ENOG4105D1H	recombination factor protein RarA
ACT74_05595	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
ACT74_05600	ENOG4105CNU	cell division protein FtsK
ACT74_05605	ENOG4105EW9	transcriptional regulator AsnC family
ACT74_05610	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ACT74_05615	ENOG4105I7R	Adenylate cyclase
ACT74_05620	ENOG4107IX6	phosphate transport regulator
ACT74_05625	ENOG4105CJ3	phosphate transporter
ACT74_05635	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACT74_05640	ENOG4108AD6	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
ACT74_05645	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
ACT74_05650	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ACT74_05660	ENOG4105DAA	L-lactate
ACT74_05665	ENOG41090HJ	UPF0265 protein
ACT74_05670	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
ACT74_05675	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACT74_05695	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
ACT74_05700	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ACT74_05705	ENOG4107RZZ	dna polymerase iii epsilon subunit
ACT74_05725	ENOG4105K4U	addiction module toxin, RelE StbE family
ACT74_05740	ENOG4105CFP	Peptidase U32
ACT74_05745	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ACT74_05750	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ACT74_05760	ENOG4105VIE	preprotein translocase, subunit YajC
ACT74_05765	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACT74_05770	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ACT74_05775	ENOG4107ENK	receptor
ACT74_05780	ENOG4108EKI	Dehydrogenase
ACT74_05785	ENOG4105CNN	ABC, transporter
ACT74_05790	ENOG4105C2J	ABC transporter
ACT74_05795	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
ACT74_05805	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ACT74_05810	ENOG4105C26	Dehydrogenase
ACT74_05815	ENOG4105CXY	transporter
ACT74_05820	ENOG4105ECY	inositol monophosphatase
ACT74_05825	ENOG4105DH8	myo-inositol catabolism
ACT74_05835	ENOG4105D7K	pfkb domain protein
ACT74_05840	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
ACT74_05845	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
ACT74_05850	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ACT74_05855	ENOG4105E61	Mannitol repressor protein
ACT74_05860	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
ACT74_05865	ENOG4105CTS	PTS system mannitol-specific
ACT74_05870	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
ACT74_05875	ENOG4108JJA	ABC, transporter
ACT74_05880	ENOG4105DDI	hemolysin-type calcium-binding region
ACT74_05895	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ACT74_05910	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
ACT74_05915	ENOG4108WPU	DNA polymerase III subunit psi
ACT74_05920	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
ACT74_05925	ENOG4105DSY	exodeoxyribonuclease V, gamma
ACT74_05960	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ACT74_05965	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ACT74_05980	ENOG4105E02	MotA TolQ exbB proton channel
ACT74_05985	ENOG4107YD3	Thioesterase
ACT74_05995	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
ACT74_06000	ENOG4105C4M	(Ubiquinol oxidase) subunit I
ACT74_06030	ENOG4105CDY	transcriptional regulatory protein
ACT74_06035	ENOG4108TIT	dATP pyrophosphohydrolase
ACT74_06040	ENOG4105K3M	)-transporter
ACT74_06045	ENOG4105C9M	aspartyl-trna synthetase
ACT74_06050	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
ACT74_06065	ENOG4105CXY	transporter
ACT74_06070	ENOG4107ENK	receptor
ACT74_06075	ENOG4108UYE	Lactoylglutathione lyase
ACT74_06080	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
ACT74_06085	ENOG4105D3Y	Na H antiporter
ACT74_06095	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ACT74_06105	ENOG4105WPN	DNA integration recombination invertion protein
ACT74_06110	ENOG4105EAH	synthase
ACT74_06125	ENOG4105QYV	Membrane
ACT74_06130	ENOG4105QYV	Membrane
ACT74_06135	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACT74_06145	ENOG4108J59	Extracellular solute-binding protein, family 5
ACT74_06150	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
ACT74_06155	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
ACT74_06160	ENOG4105C3U	ABC transporter
ACT74_06165	ENOG4108JQ7	(ABC) transporter
ACT74_06175	ENOG4105YK5	50S ribosomal protein L36
ACT74_06180	ENOG4105NRA	50s ribosomal protein l31 type b
ACT74_06185	ENOG4108URH	decarboxylase
ACT74_06195	ENOG4105MGM	doxx family
ACT74_06205	ENOG4105C03	ribonuclease
ACT74_06210	ENOG4105EI2	Pseudouridine synthase
ACT74_06215	ENOG4105K63	Thioredoxin
ACT74_06220	ENOG4105C5I	Dehydrogenase
ACT74_06225	ENOG4105C28	cystathionine
ACT74_06255	ENOG4105EN6	Membrane
ACT74_06265	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ACT74_06270	ENOG4105DFU	Cell wall formation (By similarity)
ACT74_06280	ENOG4105CA3	membrane-bound lytic murein transglycosylase
ACT74_06285	ENOG4105CUZ	uba thif-type nad fad binding protein
ACT74_06290	ENOG4105NXV	High-affinity zinc uptake system protein
ACT74_06295	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
ACT74_06300	ENOG4108VPT	UPF0234 protein
ACT74_06305	ENOG4105EAC	phosphoserine phosphatase
ACT74_06310	ENOG41062Z9	Membrane
ACT74_06320	ENOG4105CJR	Integral membrane protein (MviN
ACT74_06325	ENOG4105DTN	riboflavin biosynthesis protein ribF
ACT74_06335	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ACT74_06345	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
ACT74_06350	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACT74_06355	ENOG4105D8G	Major Facilitator superfamily
ACT74_06360	ENOG4105II7	pyrroline-5-carboxylate reductase
ACT74_06365	ENOG4105II7	pyrroline-5-carboxylate reductase
ACT74_06370	ENOG4105DH7	May be involved in recombination (By similarity)
ACT74_06380	ENOG4108UBT	opacity-associated protein
ACT74_06385	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
ACT74_06395	ENOG4105C0F	tryptophanase EC 4.1.99.1
ACT74_06405	ENOG4105WWK	YheO domain protein
ACT74_06415	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
ACT74_06420	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
ACT74_06425	ENOG4107TZ2	Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity)
ACT74_06435	ENOG4105F1A	Pyruvate formate-lyase
ACT74_06440	ENOG4105C6N	Formate acetyltransferase
ACT74_06445	ENOG4105TMB	Formate nitrite transporter
ACT74_06450	ENOG4105K59	histidine triad (HIT) protein
ACT74_06460	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
ACT74_06470	ENOG4105CTQ	phosphohexokinase
ACT74_06485	ENOG4105D1Q	UPF0246 protein
ACT74_06495	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
ACT74_06500	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ACT74_06505	ENOG4105C3F	Signal peptidase i
ACT74_06520	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ACT74_06525	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACT74_06530	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ACT74_06535	ENOG4105VG0	50S ribosomal protein l34
ACT74_06540	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ACT74_06545	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ACT74_06550	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ACT74_06555	ENOG4105DVA	methyltransferase
ACT74_06560	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACT74_06575	ENOG4105DQ6	Transposase
ACT74_06585	ENOG4105C6K	Malic enzyme
ACT74_06590	ENOG4105CBX	hi0933 family
ACT74_06595	ENOG4108DMF	Cytochrome C biogenesis protein
ACT74_06600	ENOG4107QX9	Thiol disulfide interChange protein
ACT74_06605	ENOG4105DA4	cytochrome c-type biogenesis protein
ACT74_06610	ENOG4105DVI	reductase, NrfD
ACT74_06615	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
ACT74_06620	ENOG4105JJ8	Cytochrome c nitrite reductase, pentaheme subunit
ACT74_06640	ENOG4108M1T	Cytochrome c-type biogenesis protein
ACT74_06645	ENOG4108M1T	Cytochrome c-type biogenesis protein
ACT74_06650	ENOG4107QX9	Thiol disulfide interChange protein
ACT74_06655	ENOG4105DA4	cytochrome c-type biogenesis protein
ACT74_06660	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
ACT74_06665	ENOG4105X3C	heme exporter protein
ACT74_06670	ENOG41060IM	Heme exporter protein
ACT74_06675	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
ACT74_06680	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
ACT74_06685	ENOG4105C2C	drug resistance transporter, Bcr CflA
ACT74_06690	ENOG4105I08	Pseudouridine synthase
ACT74_06695	ENOG4105C6K	Malic enzyme
ACT74_06700	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ACT74_06710	ENOG4105CGZ	zinc metallopeptidase
ACT74_06720	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
ACT74_06725	ENOG4107ZVW	dihydroneopterin aldolase
ACT74_06730	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
ACT74_06735	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
ACT74_06740	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ACT74_06745	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
ACT74_06750	ENOG4105CHM	Aminotransferase
ACT74_06755	ENOG4105E4F	Isochorismate synthase
ACT74_06760	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
ACT74_06765	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
ACT74_06770	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ACT74_06780	ENOG4105GPY	SprT protein
ACT74_06785	ENOG4105C44	Serine transporter
ACT74_06790	ENOG4105EJQ	L-serine dehydratase
ACT74_06795	ENOG4105HDK	L-asparaginase
ACT74_06805	ENOG41090FY	type IV pilus biogenesis stability protein PilW
ACT74_06810	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
ACT74_06815	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
ACT74_06820	ENOG4105CUT	histidyl-tRNA synthetase
ACT74_06825	ENOG4105N21	Membrane
ACT74_06835	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
ACT74_06840	ENOG4105C2W	permease
ACT74_06845	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ACT74_06850	ENOG4105EIN	peptidylprolyl cis-trans isomerase
ACT74_06855	ENOG4105D9M	gamma-glutamylcysteine synthetase
ACT74_06860	ENOG4108I6E	Sulfatase
ACT74_06865	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ACT74_06870	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ACT74_06885	ENOG4105NX3	Membrane
ACT74_06890	ENOG4105C59	p-type ATPase
ACT74_06900	ENOG4108Z6Z	Transcriptional regulator
ACT74_06915	ENOG4108R96	Methyltransferase, YaeB family
ACT74_06920	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
ACT74_06925	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
ACT74_06930	ENOG4105C8P	)-transporter
ACT74_06935	ENOG4105N42	UPF0307 protein
ACT74_06940	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
ACT74_06945	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
ACT74_06950	ENOG4105BZW	Glycerate kinase
ACT74_06955	ENOG4107QQ0	gntp family
ACT74_06960	ENOG4107VHA	regulatoR
ACT74_06970	ENOG4105C1J	atp-dependent rna helicase
ACT74_06975	ENOG4105RT1	May be involved in cell division (By similarity)
ACT74_06985	ENOG4108R66	Conserved Protein
ACT74_06990	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
ACT74_07005	ENOG4105D7Q	type ii secretion system
ACT74_07020	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
ACT74_07030	ENOG4105BZG	amino acid carrier protein
ACT74_07035	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
ACT74_07045	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
ACT74_07050	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACT74_07060	ENOG4105MZU	cell filamentation protein
ACT74_07065	ENOG4108IA2	Sodium pantothenate symporter
ACT74_07070	ENOG4105RG0	Membrane
ACT74_07085	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ACT74_07090	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ACT74_07095	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ACT74_07100	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
ACT74_07115	ENOG4108IPT	Naphthoate synthase
ACT74_07125	ENOG4108HYK	gCN5-related N-acetyltransferase
ACT74_07130	ENOG4105D4P	Coproporphyrinogen iii oxidase
ACT74_07135	ENOG4105XCT	Protein of unknown function (DUF2489)
ACT74_07140	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
ACT74_07145	ENOG4108Z6B	deaminase
ACT74_07155	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ACT74_07165	ENOG4105HF0	Membrane
ACT74_07170	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
ACT74_07175	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
ACT74_07180	ENOG4105C2J	ABC transporter
ACT74_07185	ENOG4105CNN	ABC, transporter
ACT74_07190	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
ACT74_07195	ENOG4108RVA	ribokinase
ACT74_07200	ENOG4105VEQ	Cold shock protein
ACT74_07230	ENOG4108ST3	glycosyltransferase
ACT74_07235	ENOG4105CH7	arginosuccinase
ACT74_07240	ENOG4105D82	Glutamate dehydrogenase
ACT74_07245	ENOG4105CH6	catalase
ACT74_07250	ENOG4105C0B	DNA polymerase III (alpha subunit)
ACT74_07255	ENOG4108IQE	Amp-dependent synthetase and ligase
ACT74_07265	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
ACT74_07270	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
ACT74_07275	ENOG4105EYA	deoxyribonuclease
ACT74_07285	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ACT74_07295	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ACT74_07310	ENOG4105DZ1	carboxypeptidase
ACT74_07315	ENOG4105K6T	rare lipoprotein A
ACT74_07320	ENOG4105CNI	cell division protein FtsW
ACT74_07325	ENOG4105CJN	penicillin-binding protein
ACT74_07335	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
ACT74_07340	ENOG4105C1J	atp-dependent rna helicase
ACT74_07345	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ACT74_07350	ENOG4107RGD	Major Facilitator superfamily
ACT74_07360	ENOG4105CHR	reductase
ACT74_07365	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ACT74_07375	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
ACT74_07380	ENOG4105VGS	50s ribosomal protein l32
ACT74_07385	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
ACT74_07390	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ACT74_07395	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
ACT74_07400	ENOG4105HSA	Protein of unknown function (DUF452)
ACT74_07405	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ACT74_07410	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
ACT74_07415	ENOG4105DJ4	phosphatidylserine decarboxylase
ACT74_07420	ENOG4108V1T	peptidylprolyl cis-trans isomerase
ACT74_07425	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACT74_07430	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACT74_07435	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ACT74_07440	ENOG4105DWK	Membrane
ACT74_07445	ENOG4107XM3	UPF0442 protein
ACT74_07450	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
ACT74_07455	ENOG4105C37	(CBS) domain
ACT74_07460	ENOG4105RX8	Protein of unknown function (DUF1523)
ACT74_07465	ENOG4105F8V	Hydrolase, tatD family
ACT74_07470	ENOG4107QRG	dna polymerase iii
ACT74_07475	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
ACT74_07480	ENOG4105HHA	aminodeoxychorismate lyase
ACT74_07485	ENOG4108YZA	Nitrogen regulatory protein pii
ACT74_07490	ENOG4105MVE	transcriptional regulator
ACT74_07495	ENOG4105ZXK	Dehydrogenase
ACT74_07500	ENOG4105G63	Type III effector Hrp-dependent
ACT74_07505	ENOG4105FB2	class II Aldolase
ACT74_07515	ENOG4105C6Z	Gluconate
ACT74_07530	ENOG4108K4B	hydrolase
ACT74_07535	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ACT74_07545	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
ACT74_07550	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
ACT74_07555	ENOG4108WFC	UPF0438 protein yifE
ACT74_07560	ENOG4108Z33	Thiol disulfide Interchange Protein
ACT74_07570	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
ACT74_07580	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
ACT74_07585	ENOG4105DE4	1-phosphofructokinase
ACT74_07590	ENOG4105DM4	PTS System
ACT74_07620	ENOG4105PM1	preprotein translocase subunit SecE
ACT74_07625	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ACT74_07640	ENOG4108VZM	50s ribosomal protein L10
ACT74_07645	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ACT74_07650	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACT74_07655	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACT74_07665	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ACT74_07670	ENOG41083MP	50s ribosomal protein l29
ACT74_07675	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ACT74_07680	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ACT74_07685	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ACT74_07690	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ACT74_07695	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACT74_07705	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ACT74_07710	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ACT74_07720	ENOG4105CMU	LysR family (Transcriptional regulator
ACT74_07730	ENOG4107QNJ	CoA-transferase subunit B
ACT74_07735	ENOG4105CRW	Short chain fatty acid transporter
ACT74_07745	ENOG4105EW9	transcriptional regulator AsnC family
ACT74_07750	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
ACT74_07755	ENOG4105C5B	carbamate kinase
ACT74_07760	ENOG4105DBV	ornithine carbamoyltransferase
ACT74_07770	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ACT74_07780	ENOG4108VVK	transcriptional Regulator, AsnC
ACT74_07785	ENOG4108I5U	Uridine phosphorylase
ACT74_07795	ENOG4105K89	arsenate reductase
ACT74_07810	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ACT74_07815	ENOG4105KJF	protein tyrosine phosphatase
ACT74_07820	ENOG4105Z2P	Protein of unknown function (DUF465)
ACT74_07825	ENOG4108YZY	peptidylprolyl cis-trans isomerase
ACT74_07835	ENOG4105KQT	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity)
ACT74_07845	ENOG4105C1A	potassium transporter peripheral membrane
ACT74_07850	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ACT74_07890	ENOG4108RR8	protoporphyrinogen oxidase
ACT74_07895	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
ACT74_07905	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ACT74_07910	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
ACT74_07915	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
ACT74_07920	ENOG4108VVQ	metallophosphoesterase
ACT74_07925	ENOG4105E0U	tyrosine-specific transport protein
ACT74_07935	ENOG4108ZT0	50S ribosomal protein l17
ACT74_07940	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ACT74_07945	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ACT74_07960	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ACT74_07970	ENOG4105VPB	50S ribosomal protein L30
ACT74_07975	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ACT74_07980	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ACT74_07985	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ACT74_07990	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ACT74_08000	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACT74_08005	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ACT74_08010	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ACT74_08020	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ACT74_08025	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
ACT74_08030	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
ACT74_08035	ENOG4105MJ2	Competence protein
ACT74_08040	ENOG4108X4Q	Hydrolase
ACT74_08045	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ACT74_08050	ENOG4105KQC	Competence protein
ACT74_08055	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ACT74_08065	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ACT74_08070	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
ACT74_08075	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ACT74_08080	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ACT74_08085	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
ACT74_08110	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ACT74_08165	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACT74_08175	ENOG4105C2D	reductase
ACT74_08180	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ACT74_08195	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
ACT74_08210	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
ACT74_08215	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
ACT74_08220	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
ACT74_08230	ENOG4105EPD	Oligopeptide transporter, Opt family
ACT74_08235	ENOG4108KBJ	Inner membrane protein YkgB
ACT74_08240	ENOG4105E7U	AraC family transcriptional regulator
ACT74_08245	ENOG4107RK2	ADP-ribose diphosphatase NudE
ACT74_08250	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
ACT74_08255	ENOG4105VEJ	Heat shock protein
ACT74_08260	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
ACT74_08265	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ACT74_08270	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
ACT74_08275	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ACT74_08280	ENOG4105D52	delta-aminolevulinic acid dehydratase
ACT74_08300	ENOG41063VX	Inherit from COG: glutaredoxin-related protein
ACT74_08310	ENOG4105N1P	Ferredoxin-type protein
ACT74_08315	ENOG4108NEM	leader-binding protein dmsD
ACT74_08320	ENOG4107KGK	dmso reductase anchor subunit
ACT74_08325	ENOG4105QAX	Iron-sulfur
ACT74_08330	ENOG4107QY8	reductase
ACT74_08370	ENOG41067XB	TonB family
ACT74_08375	ENOG4105M15	transport protein ExbD
ACT74_08380	ENOG4105M8K	biopolymer transport protein
ACT74_08385	ENOG4108JU6	CBS domain protein
ACT74_08390	ENOG4106KVJ	cytochrome C assembly protein
ACT74_08395	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACT74_08400	ENOG4105C4W	S-formylglutathione hydrolase
ACT74_08405	ENOG4107QPD	alcohol dehydrogenase
ACT74_08415	ENOG4105EMU	Dehydrogenase
ACT74_08420	ENOG4107QTF	adenylosuccinate lyase
ACT74_08425	ENOG41075W9	High frequency lysogenization protein HflD homolog
ACT74_08435	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
ACT74_08440	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ACT74_08445	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ACT74_08450	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
ACT74_08455	ENOG41062MS	nucleotidyltransferase substrate binding protein
ACT74_08460	ENOG41060A7	DNA polymerase beta domain protein region
ACT74_08465	ENOG4105WV0	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
ACT74_08480	ENOG4105DJF	DNA polymerase III, delta' subunit
ACT74_08485	ENOG4105M6F	mutator MutT protein
ACT74_08490	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ACT74_08505	ENOG4105W1Y	Transcriptional regulator
ACT74_08510	ENOG4105DQ6	Transposase
ACT74_08525	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ACT74_08530	ENOG4108UUM	single-stranded DNA-binding protein
ACT74_08605	ENOG4105DFE	Dna adenine methylase
ACT74_08610	ENOG4105D49	3-dehydroquinate synthase
ACT74_08615	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ACT74_08620	ENOG4105E4G	Type IV pilus
ACT74_08645	ENOG4108JQC	penicillin-binding protein 1A
ACT74_08650	ENOG4105D6S	protein involved in catabolism of external DNA
ACT74_08655	ENOG4105DC8	reductase
ACT74_08660	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
ACT74_08665	ENOG4105YP7	UPF0270 protein
ACT74_08670	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
ACT74_08680	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
ACT74_08695	ENOG4105W0E	50S ribosomal protein L33
ACT74_08715	ENOG4105W1T	Glycosyl Transferase
ACT74_08725	ENOG4105W1T	Glycosyl Transferase
ACT74_08735	ENOG4108SEH	involved in lipopolysaccharide biosynthesis
ACT74_08740	ENOG4105C25	Primosomal protein n'
ACT74_08745	ENOG41063M6	Cell Division Protein
ACT74_08750	ENOG4105Y7M	Transcriptional regulator, TetR family
ACT74_08755	ENOG410624X	efflux transporter, rnd family, mfp subunit
ACT74_08760	ENOG4105BZS	acriflavin resistance protein
ACT74_08770	ENOG4107QUT	magnesium and cobalt transport protein CorA
ACT74_08775	ENOG4108VIA	integral membrane protein
ACT74_08780	ENOG4105VZ9	UPF0235 protein
ACT74_08785	ENOG4108RCM	Nitroreductase
ACT74_08790	ENOG4105E0M	Sulfatase
ACT74_08795	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
ACT74_08800	ENOG4105C34	Pseudouridine synthase
ACT74_08805	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACT74_08810	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
ACT74_08815	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
ACT74_08820	ENOG4105E07	UPF0149 protein
ACT74_08825	ENOG4107RAQ	aminopeptidase
ACT74_08855	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
ACT74_08860	ENOG4105DFF	Rod shape-determining protein mreb
ACT74_08865	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ACT74_08870	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ACT74_08875	ENOG4105CXY	transporter
ACT74_08880	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
ACT74_08885	ENOG4105C79	DNA protecting protein DprA
ACT74_08890	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ACT74_08905	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
ACT74_08910	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
ACT74_08915	ENOG4105E55	glycerol-3-phosphate acyltransferase
ACT74_08920	ENOG4105BZ1	(ABC) transporter
ACT74_08925	ENOG4105E7U	AraC family transcriptional regulator
ACT74_08935	ENOG4105DKP	glycosyl transferase, family 9
ACT74_08950	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ACT74_08955	ENOG4106WTF	Glycosyl transferase, family 2
ACT74_08960	ENOG4108K5P	(LipO)protein
ACT74_08970	ENOG4108UM1	dedA family
ACT74_08975	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ACT74_08980	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
ACT74_08990	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
ACT74_08995	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
ACT74_09000	ENOG4105DJV	ribulose-phosphate 3-epimerase
ACT74_09005	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
ACT74_09010	ENOG4105CAK	Cell division ATP-binding protein ftsE
ACT74_09015	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
ACT74_09020	ENOG4105C7B	Threonine dehydratase
ACT74_09025	ENOG4105C7B	Threonine dehydratase
ACT74_09035	ENOG4105DQF	Hydrolase
ACT74_09040	ENOG4108EUD	Lysophospholipase
ACT74_09045	ENOG4105PF3	O-Antigen polymerase
ACT74_09050	ENOG4105D2N	Aldolase
ACT74_09060	ENOG41083KI	ribonuclease, T2
ACT74_09065	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ACT74_09070	ENOG4105EIB	trna rrna methyltransferase
ACT74_09075	ENOG4105JIM	Phosphatidylserine synthase
ACT74_09080	ENOG4105DQ6	Transposase
ACT74_09095	ENOG4105CMG	Carbohydrate kinase
ACT74_09100	ENOG4105C93	Xylose Isomerase
ACT74_09105	ENOG4105DFW	ABC transporter
ACT74_09110	ENOG4105C2J	ABC transporter
ACT74_09115	ENOG4108HWW	ABC transporter
ACT74_09120	ENOG4105C87	Aminotransferase class I and II
ACT74_09125	ENOG4105DFD	Na H antiporter
ACT74_09130	ENOG4105T16	Transcriptional regulator (AraC family)
ACT74_09135	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ACT74_09140	ENOG4108EQA	pts system
ACT74_09145	ENOG4105ETZ	PTS System
ACT74_09150	ENOG4105F3R	pts system mannose fructose sorbose family iid
ACT74_09160	ENOG4105EKX	Restriction modification system DNA (Specificity
ACT74_09180	ENOG4107RUE	extracellular solute-binding protein family 1
ACT74_09185	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ACT74_09195	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ACT74_09205	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ACT74_09230	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ACT74_09235	ENOG4105KVH	Transcriptional regulator
ACT74_09240	ENOG4105ECR	NmrA family
ACT74_09250	ENOG4105QTB	Flavodoxin
ACT74_09255	ENOG4105N4M	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
ACT74_09260	ENOG4105CBT	Fructose-1,6-bisphosphatase
ACT74_09265	ENOG4105D7W	serine acetyltransferase
ACT74_09270	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ACT74_09275	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
ACT74_09280	ENOG4107YZP	Rhodanese domain protein
ACT74_09285	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
ACT74_09290	ENOG4108JJ9	ABC, transporter
ACT74_09295	ENOG4105BZ1	(ABC) transporter
ACT74_09300	ENOG4105EJ2	Transcriptional regulator
ACT74_09305	ENOG4105C5Q	Transcriptional regulator
ACT74_09310	ENOG4105EHV	domain protein
ACT74_09315	ENOG4105VRX	Protein slyX homolog
ACT74_09320	ENOG4108V1T	peptidylprolyl cis-trans isomerase
ACT74_09325	ENOG4105WWK	YheO domain protein
ACT74_09330	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
ACT74_09335	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
ACT74_09345	ENOG4105CDA	abc transporter atp-binding protein
ACT74_09350	ENOG4105E5Q	amino acid AbC transporter
ACT74_09355	ENOG4105EAB	amino acid AbC transporter
ACT74_09360	ENOG4105CJP	fad dependent oxidoreductase
ACT74_09385	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACT74_09390	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
ACT74_09395	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ACT74_09405	ENOG4107FB0	transcriptional regulator DeoR family
ACT74_09420	ENOG410689M	(LipO)protein
ACT74_09430	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ACT74_09435	ENOG4105C5H	ABC transporter
ACT74_09535	ENOG4105C5H	ABC transporter
ACT74_09540	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ACT74_09545	ENOG4105Y3E	Modulates RecA activity (By similarity)
ACT74_09550	ENOG4105KME	endoribonuclease L-psp
ACT74_09555	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ACT74_09560	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ACT74_09585	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
ACT74_09590	ENOG4108HPI	phosphatidate Cytidylyltransferase
ACT74_09600	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
ACT74_09605	ENOG4107QWE	)-transporter
ACT74_09615	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACT74_09620	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACT74_09625	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ACT74_09630	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ACT74_09640	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACT74_09645	ENOG4105DZP	Membrane-associated zinc metalloprotease
ACT74_09650	ENOG4105KNE	Phosphatidate cytidylyltransferase
ACT74_09655	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ACT74_09665	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ACT74_09675	ENOG4105D0C	transport protein
ACT74_09680	ENOG4105CQ0	ABC transporter
ACT74_09690	ENOG4105E98	transcriptional regulator DeoR family
ACT74_09695	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
ACT74_09705	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
ACT74_09710	ENOG4108TEB	UPF0114 protein
ACT74_09715	ENOG4105CGY	Dna recombination protein
ACT74_09720	ENOG4108WI1	Dna topoisomerase
ACT74_09725	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ACT74_09730	ENOG4105E2X	shikimate dehydrogenase
ACT74_09735	ENOG4105DTR	rard protein
ACT74_09740	ENOG4105EMY	transcriptional regulator
ACT74_09745	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ACT74_09750	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ACT74_09755	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ACT74_09765	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ACT74_09775	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ACT74_09785	ENOG4105D4A	Cell wall formation (By similarity)
ACT74_09790	ENOG4105BZU	Histidine kinase
ACT74_09805	ENOG4108BGM	Quinol dehydrogenase periplasmic component
ACT74_09810	ENOG4105GXZ	Ferredoxin-type protein NapH
ACT74_09815	ENOG4105IYZ	Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity)
ACT74_09820	ENOG4105CUW	cytochrome C-TYPE protein
ACT74_09825	ENOG4106032	Glutathionylspermidine synthase
ACT74_09830	ENOG4105XA0	heptosyltransferase ii
ACT74_09840	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
ACT74_09845	ENOG4106W3N	
ACT74_09850	ENOG4105CGH	5'-nucleotidase
ACT74_09865	ENOG4105C2M	dna polymerase I
ACT74_09880	ENOG4105C4R	Atp-dependent dna helicase
ACT74_09905	ENOG4107VXZ	Hydrolase
ACT74_09910	ENOG4108UW5	maltose o-acetyltransferase
ACT74_09915	ENOG4105W39	Membrane
ACT74_09925	ENOG4105D3G	Pseudouridine synthase
ACT74_09935	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
ACT74_09940	ENOG4105C1J	atp-dependent rna helicase
ACT74_09970	ENOG4105CXY	transporter
ACT74_09980	ENOG4105CND	Glycosyl transferase, family 2
ACT74_09985	ENOG4107BJW	polysaccharide deacetylase
ACT74_10000	ENOG4105D9N	nucleoside
ACT74_10005	ENOG410667J	hydrolase
ACT74_10010	ENOG4105F3R	pts system mannose fructose sorbose family iid
ACT74_10015	ENOG4105ETZ	PTS System
ACT74_10020	ENOG4108EQA	pts system
ACT74_10025	ENOG4106H78	methyltransferase
ACT74_10030	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACT74_10035	ENOG4105C31	Tryptophanyl-tRNA synthetase
ACT74_10040	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ACT74_10045	ENOG4105ERG	peptidase m48, ste24p
ACT74_10050	ENOG4105F0N	pyrophosphate phospho-hydrolase
ACT74_10055	ENOG4105CIC	tryptophan-specific transport protein
ACT74_10075	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
ACT74_10080	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
ACT74_10085	ENOG410903C	(LipO)protein
ACT74_10090	ENOG4105XWI	UPF0304 protein
ACT74_10095	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ACT74_10100	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
ACT74_10105	ENOG41063SB	peptidase
ACT74_10110	ENOG4105PXI	polysaccharide deacetylase
ACT74_10195	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
ACT74_10220	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ACT74_10225	ENOG4108MJ5	VirK protein
ACT74_10230	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
ACT74_10240	ENOG4105D01	(LipO)protein
ACT74_10250	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
ACT74_10255	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
