locus-tag	class	description
NJ8700_00020	COG0252	asparaginase activity
NJ8700_00030	COG3063	Type IV pilus biogenesis stability protein PilW
NJ8700_00035	COG1426	Protein conserved in bacteria
NJ8700_00050	COG2976	Protein conserved in bacteria
NJ8700_00060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NJ8700_00065	COG2233	PERMEase
NJ8700_00075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NJ8700_00080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NJ8700_00090	COG0659	secondary active sulfate transmembrane transporter activity
NJ8700_00095	COG0800	Aldolase
NJ8700_00105	COG0280	phosphate acetyltransferase
NJ8700_00105	COG0281	malic enzyme
NJ8700_00115	COG2814	Major facilitator Superfamily
NJ8700_00120	COG4133	protoheme IX ABC transporter activity
NJ8700_00125	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NJ8700_00130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NJ8700_00135	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NJ8700_00145	COG1138	Cytochrome C-type biogenesis protein
NJ8700_00150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJ8700_00180	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NJ8700_00185	COG0437	4 iron, 4 sulfur cluster binding
NJ8700_00190	COG3301	Polysulphide reductase, NrfD
NJ8700_00195	COG1138	Cytochrome C-type biogenesis protein
NJ8700_00200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJ8700_00205	COG4235	cytochrome complex assembly
NJ8700_00205	COG3088	subunit of a heme lyase
NJ8700_00210	COG2081	HI0933 family
NJ8700_00215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NJ8700_00225	COG1305	Transglutaminase-like
NJ8700_00235	COG2608	mercury ion transmembrane transporter activity
NJ8700_00245	COG2226	methyltransferase
NJ8700_00255	COG0592	DNA-directed DNA polymerase activity
NJ8700_00265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NJ8700_00285	COG0602	queuosine metabolic process
NJ8700_00290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NJ8700_00290	COG1328	CTP reductase activity
NJ8700_00300	COG1022	Amp-dependent synthetase and ligase
NJ8700_00305	COG0587	DNA-directed DNA polymerase activity
NJ8700_00310	COG0121	glutamine amidotransferase
NJ8700_00315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NJ8700_00345	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NJ8700_00355	COG1278	Cold shock
NJ8700_00360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NJ8700_00365	COG0494	nUDIX hydrolase
NJ8700_00370	COG0730	response to heat
NJ8700_00380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NJ8700_00385	COG0590	tRNA wobble adenosine to inosine editing
NJ8700_00390	COG3078	GTPase activator activity
NJ8700_00400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NJ8700_00405	COG0456	acetyltransferase
NJ8700_00410	COG0149	triose-phosphate isomerase activity
NJ8700_00415	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NJ8700_00430	COG0511	ligase activity, forming carbon-carbon bonds
NJ8700_00435	COG0439	Biotin carboxylase
NJ8700_00455	COG0681	Belongs to the peptidase S26 family
NJ8700_00470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NJ8700_00485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NJ8700_00495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NJ8700_00510	COG0537	adenosine 5'-monophosphoramidase activity
NJ8700_00515	COG2116	formate transmembrane transporter activity
NJ8700_00520	COG1882	Formate acetyltransferase
NJ8700_00530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NJ8700_00535	COG0697	spore germination
NJ8700_00545	COG0204	Acyl-transferase
NJ8700_00555	COG5413	integral membrane protein
NJ8700_00560	COG2964	Protein conserved in bacteria
NJ8700_00565	COG0814	amino acid
NJ8700_00570	COG3033	Beta-eliminating lyase
NJ8700_00580	COG1509	lysine 2,3-aminomutase activity
NJ8700_00585	COG3061	Opacity-associated protein A
NJ8700_00585	COG3266	domain, Protein
NJ8700_00605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NJ8700_00610	COG2814	Major facilitator Superfamily
NJ8700_00615	COG4974	Belongs to the 'phage' integrase family
NJ8700_00620	COG0544	peptidyl-prolyl cis-trans isomerase activity
NJ8700_00625	COG0330	HflC and HflK could
NJ8700_00630	COG0330	HflC and HflK could
NJ8700_00640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NJ8700_00655	COG0527	aspartate kinase activity
NJ8700_00655	COG0460	homoserine dehydrogenase
NJ8700_00675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NJ8700_00680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NJ8700_00705	COG0174	glutamine synthetase
NJ8700_00710	COG0861	Integral membrane protein TerC family
NJ8700_00720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NJ8700_00725	COG2067	long-chain fatty acid transport protein
NJ8700_00730	COG3691	Protein conserved in bacteria
NJ8700_00735	COG0471	metal ion transport
NJ8700_00740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NJ8700_00745	COG1575	Belongs to the MenA family. Type 1 subfamily
NJ8700_00750	COG1720	tRNA m6t6A37 methyltransferase activity
NJ8700_00755	COG0789	Transcriptional regulator
NJ8700_00760	COG2608	mercury ion transmembrane transporter activity
NJ8700_00765	COG2217	Heavy metal translocating P-type atpase
NJ8700_00770	COG3739	integral membrane protein
NJ8700_00780	COG0740	serine-type endopeptidase activity
NJ8700_00790	COG2194	sulfuric ester hydrolase activity
NJ8700_00800	COG1181	Belongs to the D-alanine--D-alanine ligase family
NJ8700_00800	COG2918	glutathione biosynthetic process
NJ8700_00850	COG4964	Belongs to the GSP D family
NJ8700_00875	COG1702	phosphate starvation-inducible protein PhoH
NJ8700_00880	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NJ8700_00890	COG1444	tRNA N-acetyltransferase activity
NJ8700_00900	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NJ8700_00920	COG1126	abc transporter atp-binding protein
NJ8700_00925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJ8700_00930	COG4215	(ABC) transporter
NJ8700_00935	COG4160	amino acid transport
NJ8700_00940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJ8700_00950	COG1966	Carbon starvation protein
NJ8700_00965	COG3116	cell division
NJ8700_00970	COG0768	penicillin binding
NJ8700_00975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NJ8700_00980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NJ8700_01000	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NJ8700_01015	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NJ8700_01020	COG0849	cell division
NJ8700_01025	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NJ8700_01040	COG1605	Chorismate mutase
NJ8700_01040	COG0077	Prephenate dehydratase
NJ8700_01050	COG0326	Molecular chaperone. Has ATPase activity
NJ8700_01055	COG1393	Belongs to the ArsC family
NJ8700_01070	COG1876	peptidase activity
NJ8700_01075	COG0494	nUDIX hydrolase
NJ8700_01080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NJ8700_01110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NJ8700_01120	COG0471	metal ion transport
NJ8700_01125	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NJ8700_01125	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NJ8700_01130	COG3051	citrate lyase alpha subunit
NJ8700_01135	COG2301	Belongs to the HpcH HpaI aldolase family
NJ8700_01145	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NJ8700_01150	COG4535	Mg2 and Co2 transporter CorC
NJ8700_01170	COG0105	UTP biosynthetic process
NJ8700_01180	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NJ8700_01195	COG3501	Rhs element vgr protein
NJ8700_01205	COG3209	COG3209 Rhs family protein
NJ8700_01230	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NJ8700_01235	COG1530	ribonuclease E activity
NJ8700_01240	COG2999	glutathione oxidoreductase activity
NJ8700_01245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NJ8700_01255	COG0725	ABC transporter, periplasmic molybdate-binding protein
NJ8700_01260	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NJ8700_01265	COG3842	ATPase activity
NJ8700_01270	COG0157	Belongs to the NadC ModD family
NJ8700_01285	COG4953	penicillin-binding protein 1C
NJ8700_01355	COG1823	symporter activity
NJ8700_01365	COG0795	lipopolysaccharide-transporting ATPase activity
NJ8700_01370	COG0795	lipopolysaccharide-transporting ATPase activity
NJ8700_01375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NJ8700_01380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJ8700_01390	COG0739	heme binding
NJ8700_01405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NJ8700_01415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NJ8700_01425	COG0617	tRNA 3'-terminal CCA addition
NJ8700_01430	COG4991	sh3 domain protein
NJ8700_01435	COG0306	phosphate transporter
NJ8700_01445	COG3025	triphosphatase activity
NJ8700_01450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NJ8700_01455	COG1522	sequence-specific DNA binding
NJ8700_01470	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NJ8700_01475	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NJ8700_01525	COG1518	maintenance of DNA repeat elements
NJ8700_01535	COG1263	PTS System
NJ8700_01535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJ8700_01535	COG2190	(PTS) system
NJ8700_01545	COG0058	SHG alpha-glucan phosphorylase activity
NJ8700_01550	COG2188	Transcriptional regulator
NJ8700_01565	COG0583	DNA-binding transcription factor activity
NJ8700_01570	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NJ8700_01575	COG1687	branched-chain amino acid
NJ8700_01580	COG0612	Peptidase, M16
NJ8700_01585	COG4771	TonB-dependent receptor
NJ8700_01590	COG2990	Protein conserved in bacteria
NJ8700_01595	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NJ8700_01600	COG0539	negative regulation of cytoplasmic translation
NJ8700_01605	COG0776	regulation of translation
NJ8700_01610	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
NJ8700_01615	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NJ8700_01625	COG0023	Translation Initiation Factor
NJ8700_01630	COG3094	Invasion gene expression up-regulator, SirB
NJ8700_01635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NJ8700_01645	COG0735	belongs to the Fur family
NJ8700_01650	COG0716	FMN binding
NJ8700_01660	COG0596	Alpha beta hydrolase
NJ8700_01665	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NJ8700_01670	COG0318	PFAM AMP-dependent synthetase and ligase
NJ8700_01675	COG3264	Mechanosensitive ion channel
NJ8700_01675	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NJ8700_01685	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
NJ8700_01690	COG0730	response to heat
NJ8700_01695	COG1560	Kdo2-lipid A biosynthetic process
NJ8700_01700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NJ8700_01705	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NJ8700_01710	COG3021	interspecies interaction between organisms
NJ8700_01715	COG0251	oxidation-reduction process
NJ8700_01725	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NJ8700_01735	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NJ8700_01740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NJ8700_01750	COG0602	queuosine metabolic process
NJ8700_01755	COG0720	synthase
NJ8700_01785	COG1289	transmembrane transporter activity
NJ8700_01790	COG3304	Inner membrane component domain
NJ8700_01810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJ8700_01815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NJ8700_01820	COG1121	(ABC) transporter
NJ8700_01830	COG2920	part of a sulfur-relay system
NJ8700_01840	COG3105	Protein conserved in bacteria
NJ8700_01850	COG1944	ATP diphosphatase activity
NJ8700_01870	COG2226	methyltransferase
NJ8700_01885	COG1846	Transcriptional regulator
NJ8700_01885	COG1940	carbohydrate kinase activity
NJ8700_01910	COG0405	Gamma-glutamyltransferase
NJ8700_01925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NJ8700_01945	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NJ8700_01955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NJ8700_01960	COG1177	transmembrane transport
NJ8700_01965	COG1176	ABC-type spermidine putrescine transport system, permease component I
NJ8700_01970	COG3842	ATPase activity
NJ8700_01980	COG3008	intermembrane lipid transfer
NJ8700_01985	COG2995	paraquat-inducible protein a
NJ8700_01995	COG0793	Belongs to the peptidase S41A family
NJ8700_02000	COG2989	Protein conserved in bacteria
NJ8700_02005	COG3108	Peptidase M15
NJ8700_02010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NJ8700_02015	COG0567	Dehydrogenase, E1 component
NJ8700_02020	COG0508	dehydrogenase complex catalyzes the overall conversion of
NJ8700_02030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NJ8700_02060	COG3070	regulator of competence-specific genes
NJ8700_02080	COG0745	RESPONSE REGULATOR receiver
NJ8700_02085	COG0642	Histidine kinase
NJ8700_02095	COG2814	Major facilitator Superfamily
NJ8700_02100	COG0375	protein maturation
NJ8700_02110	COG2252	PERMEase
NJ8700_02120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NJ8700_02125	COG0825	malonyl-CoA metabolic process
NJ8700_02260	COG4626	Terminase
NJ8700_02260	COG1802	Transcriptional regulator
NJ8700_02440	COG0582	viral genome integration into host DNA
NJ8700_02455	COG3069	C4-dicarboxylate transmembrane transporter activity
NJ8700_02480	COG0517	IMP dehydrogenase activity
NJ8700_02480	COG0516	GMP reductase activity
NJ8700_02490	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NJ8700_02490	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NJ8700_02500	COG0351	phosphomethylpyrimidine kinase
NJ8700_02505	COG4143	(ABC) transporter
NJ8700_02510	COG1178	ABC-type Fe3 transport system permease component
NJ8700_02515	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NJ8700_02540	COG1263	PTS System
NJ8700_02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJ8700_02540	COG2190	(PTS) system
NJ8700_02550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NJ8700_02550	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NJ8700_02555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NJ8700_02560	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NJ8700_02570	COG1737	Transcriptional regulator
NJ8700_02575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NJ8700_02580	COG0363	glucosamine-6-phosphate deaminase activity
NJ8700_02585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NJ8700_02590	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NJ8700_02605	COG0247	lactate metabolic process
NJ8700_02605	COG0277	FAD linked oxidase domain protein
NJ8700_02620	COG1704	LemA family
NJ8700_02645	COG2363	Small membrane protein
NJ8700_02650	COG1643	Atp-dependent helicase
NJ8700_02665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJ8700_02670	COG1136	(ABC) transporter
NJ8700_02670	COG0577	efflux transmembrane transporter activity
NJ8700_02680	COG0577	efflux transmembrane transporter activity
NJ8700_02695	COG0672	)-iron permease
NJ8700_02700	COG1556	Lactate utilization protein
NJ8700_02710	COG0247	lactate metabolic process
NJ8700_02715	COG1620	l-lactate permease
NJ8700_02720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NJ8700_02725	COG3112	Uncharacterised protein family (UPF0231)
NJ8700_02730	COG0316	Belongs to the HesB IscA family
NJ8700_02735	COG0024	Methionine aminopeptidase
NJ8700_02745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NJ8700_02750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NJ8700_02795	COG3787	Belongs to the UPF0306 family
NJ8700_02800	COG4172	Belongs to the ABC transporter superfamily
NJ8700_02805	COG4172	Belongs to the ABC transporter superfamily
NJ8700_02810	COG4171	peptide transport system, permease
NJ8700_02815	COG4168	peptide transport system, permease
NJ8700_02820	COG4166	transmembrane transport
NJ8700_02835	COG3106	COG3106 Predicted ATPase
NJ8700_02845	COG3283	Transcriptional regulator of aromatic amino acids metabolism
NJ8700_02850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NJ8700_02855	COG1923	regulation of RNA biosynthetic process
NJ8700_02865	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NJ8700_02870	COG0860	N-Acetylmuramoyl-L-alanine amidase
NJ8700_02870	COG1388	LysM domain
NJ8700_02875	COG0802	atpase or kinase
NJ8700_02880	COG2194	sulfuric ester hydrolase activity
NJ8700_02895	COG1162	GTPase activity
NJ8700_02900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJ8700_02905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NJ8700_02910	COG2190	(PTS) system
NJ8700_02915	COG0339	signal peptide processing
NJ8700_02920	COG2832	Protein of unknown function (DUF454)
NJ8700_02925	COG4166	transmembrane transport
NJ8700_02940	COG0671	phosphoesterase, PA-phosphatase related
NJ8700_02945	COG1940	carbohydrate kinase activity
NJ8700_02950	COG1216	Glycosyl transferase, family 2
NJ8700_02955	COG2951	lytic endotransglycosylase activity
NJ8700_02970	COG2246	polysaccharide biosynthetic process
NJ8700_03005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NJ8700_03010	COG0708	Exodeoxyribonuclease III
NJ8700_03015	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NJ8700_03020	COG1088	dTDP-glucose 4,6-dehydratase activity
NJ8700_03035	COG0778	Nitroreductase
NJ8700_03040	COG0616	signal peptide processing
NJ8700_03045	COG1605	Chorismate mutase
NJ8700_03045	COG0287	Prephenate dehydrogenase
NJ8700_03050	COG0009	L-threonylcarbamoyladenylate synthase
NJ8700_03060	COG0583	DNA-binding transcription factor activity
NJ8700_03070	COG2351	hydroxyisourate hydrolase activity
NJ8700_03080	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NJ8700_03085	COG0508	dehydrogenase complex catalyzes the overall conversion of
NJ8700_03090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NJ8700_03100	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NJ8700_03110	COG0512	Glutamine amidotransferase of anthranilate synthase
NJ8700_03115	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NJ8700_03130	COG1943	Transposase
NJ8700_03135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJ8700_03170	COG4591	ABC-type transport system involved in lipoprotein release permease component
NJ8700_03180	COG4591	ABC-type transport system involved in lipoprotein release permease component
NJ8700_03185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NJ8700_03190	COG0305	Participates in initiation and elongation during chromosome replication
NJ8700_03205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NJ8700_03215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NJ8700_03220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NJ8700_03225	COG1280	lysine exporter protein (LysE YggA)
NJ8700_03235	COG0633	Ferredoxin
NJ8700_03240	COG0471	metal ion transport
NJ8700_03245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJ8700_03255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJ8700_03260	COG1840	ABC-type Fe3 transport system, periplasmic component
NJ8700_03270	COG3842	ATPase activity
NJ8700_03275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NJ8700_03280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NJ8700_03285	COG3955	Domain of unknown function (DUF1919)
NJ8700_03290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NJ8700_03295	COG0785	Cytochrome C biogenesis protein
NJ8700_03300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NJ8700_03300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NJ8700_03305	COG0288	reversible hydration of carbon dioxide
NJ8700_03310	COG2823	Periplasmic or secreted lipoprotein
NJ8700_03315	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NJ8700_03330	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NJ8700_03340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NJ8700_03345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NJ8700_03360	COG0616	signal peptide processing
NJ8700_03390	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NJ8700_03395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NJ8700_03400	COG3738	Protein conserved in bacteria
NJ8700_03410	COG0142	geranyltranstransferase activity
NJ8700_03425	COG2819	hydrolase of the alpha beta superfamily
NJ8700_03435	COG0285	dihydrofolate synthase activity
NJ8700_03440	COG0588	phosphoglycerate mutase activity
NJ8700_03445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NJ8700_03450	COG2431	L-lysine efflux transmembrane transporter activity
NJ8700_03455	COG0564	pseudouridine synthase activity
NJ8700_03465	COG2824	Alkylphosphonate utilization operon protein PhnA
NJ8700_03485	COG1538	Outer membrane efflux protein
NJ8700_03490	COG1136	(ABC) transporter
NJ8700_03490	COG0577	efflux transmembrane transporter activity
NJ8700_03495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJ8700_03505	COG2983	Belongs to the UPF0260 family
NJ8700_03510	COG1640	4-alpha-glucanotransferase
NJ8700_03520	COG1523	belongs to the glycosyl hydrolase 13 family
NJ8700_03535	COG0058	SHG alpha-glucan phosphorylase activity
NJ8700_03545	COG0586	Pfam SNARE associated Golgi protein
NJ8700_03560	COG1686	Belongs to the peptidase S11 family
NJ8700_03565	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
NJ8700_03580	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NJ8700_03585	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NJ8700_03590	COG0697	spore germination
NJ8700_03595	COG2925	Exonuclease
NJ8700_03600	COG1528	Iron-storage protein
NJ8700_03605	COG1528	Iron-storage protein
NJ8700_03610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NJ8700_03615	COG0589	response to stress
NJ8700_03620	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
NJ8700_03630	COG0583	DNA-binding transcription factor activity
NJ8700_03635	COG0613	PHP domain protein
NJ8700_03650	COG0308	aminopeptidase N
NJ8700_03655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NJ8700_03660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NJ8700_03665	COG1448	Aminotransferase
NJ8700_03675	COG1120	ATPase activity
NJ8700_03685	COG3585	molybdate ion transport
NJ8700_03690	COG1309	transcriptional regulator
NJ8700_03695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJ8700_03700	COG0842	Transport permease protein
NJ8700_03700	COG1129	ABC transporter
NJ8700_03705	COG0842	Transport permease protein
NJ8700_03710	COG1538	Outer membrane efflux protein
NJ8700_03730	COG0791	NLP P60 protein
NJ8700_03745	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NJ8700_03750	COG0501	Belongs to the peptidase M48B family
NJ8700_03760	COG0517	IMP dehydrogenase activity
NJ8700_03760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NJ8700_03765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NJ8700_03775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NJ8700_03780	COG0512	Glutamine amidotransferase of anthranilate synthase
NJ8700_03785	COG1942	4-Oxalocrotonate Tautomerase
NJ8700_03795	COG0134	indole-3-glycerol-phosphate synthase activity
NJ8700_03795	COG0135	phosphoribosylanthranilate isomerase activity
NJ8700_03800	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NJ8700_03805	COG0437	4 iron, 4 sulfur cluster binding
NJ8700_03810	COG5557	Pfam Polysulphide reductase, NrfD
NJ8700_03815	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
NJ8700_03820	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NJ8700_03825	COG1773	rubredoxin
NJ8700_03830	COG0298	carbon dioxide binding
NJ8700_03840	COG3630	sodium ion export across plasma membrane
NJ8700_03845	COG0511	ligase activity, forming carbon-carbon bonds
NJ8700_03845	COG5016	pyruvate
NJ8700_03855	COG4221	oxidoreductase activity
NJ8700_03860	COG0133	tryptophan synthase activity
NJ8700_03870	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NJ8700_03880	COG0469	pyruvate kinase activity
NJ8700_03895	COG1879	ABC-type sugar transport system periplasmic component
NJ8700_03915	COG2390	Transcriptional regulator
NJ8700_03940	COG2969	positive regulation of protein catabolic process
NJ8700_03950	COG0314	molybdopterin synthase activity
NJ8700_03955	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NJ8700_03965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NJ8700_03990	COG3005	denitrification pathway
NJ8700_04005	COG3005	denitrification pathway
NJ8700_04010	COG0243	molybdopterin cofactor binding
NJ8700_04015	COG2315	Protein conserved in bacteria
NJ8700_04020	COG0366	Alpha amylase catalytic
NJ8700_04025	COG1263	PTS System
NJ8700_04025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJ8700_04030	COG0101	tRNA pseudouridine synthase activity
NJ8700_04050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NJ8700_04055	COG1074	ATP-dependent DNA helicase activity
NJ8700_04060	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NJ8700_04065	COG2252	PERMEase
NJ8700_04075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NJ8700_04080	COG1067	ATP-dependent peptidase activity
NJ8700_04090	COG1278	Cold shock
NJ8700_04105	COG3098	single-species biofilm formation
NJ8700_04115	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NJ8700_04120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NJ8700_04120	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NJ8700_04125	COG3101	peptidyl-lysine hydroxylation
NJ8700_04130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NJ8700_04140	COG0788	formyltetrahydrofolate deformylase activity
NJ8700_04145	COG2916	Histone family protein nucleoid-structuring protein H-NS
NJ8700_04150	COG1757	Na H antiporter
NJ8700_04185	COG1609	Transcriptional regulator
NJ8700_04190	COG2949	membrane
NJ8700_04195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NJ8700_04210	COG3099	Belongs to the UPF0263 family
NJ8700_04215	COG4178	(ABC) transporter
NJ8700_04220	COG4774	siderophore transport
NJ8700_04230	COG0307	riboflavin synthase, alpha
NJ8700_04235	COG1534	Rna-binding protein
NJ8700_04240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NJ8700_04245	COG2027	D-alanyl-D-alanine carboxypeptidase
NJ8700_04255	COG0303	'Molybdopterin
NJ8700_04260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NJ8700_04270	COG4580	involved in the transport of maltose and maltodextrins
NJ8700_04280	COG3842	ATPase activity
NJ8700_04285	COG2182	Extracellular solute-binding protein
NJ8700_04290	COG2182	Extracellular solute-binding protein
NJ8700_04300	COG3833	ABC-type maltose transport systems, permease component
NJ8700_04305	COG0366	Alpha amylase catalytic
NJ8700_04380	COG2909	trisaccharide binding
NJ8700_04385	COG0058	SHG alpha-glucan phosphorylase activity
NJ8700_04390	COG1640	4-alpha-glucanotransferase
NJ8700_04400	COG0163	prenyltransferase activity
NJ8700_04410	COG1286	toxin biosynthetic process
NJ8700_04420	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NJ8700_04425	COG0857	belongs to the CobB CobQ family
NJ8700_04425	COG0280	phosphate acetyltransferase
NJ8700_04440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NJ8700_04445	COG0617	tRNA 3'-terminal CCA addition
NJ8700_04455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NJ8700_04460	COG0658	competence protein
NJ8700_04460	COG2333	competence protein COMEC
NJ8700_04465	COG1132	(ABC) transporter
NJ8700_04470	COG1663	tetraacyldisaccharide 4'-kinase activity
NJ8700_04475	COG2835	tetraacyldisaccharide 4'-kinase activity
NJ8700_04485	COG0322	excinuclease ABC activity
NJ8700_04515	COG1176	ABC-type spermidine putrescine transport system, permease component I
NJ8700_04520	COG1175	transmembrane transport
NJ8700_04540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NJ8700_04545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NJ8700_04560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NJ8700_04565	COG1621	beta-fructofuranosidase activity
NJ8700_04580	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NJ8700_04590	COG0195	Participates in both transcription termination and antitermination
NJ8700_04610	COG3100	YcgL domain-containing protein
NJ8700_04625	COG2062	phosphohistidine phosphatase, SixA
NJ8700_04635	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NJ8700_04640	COG2962	Rard protein
NJ8700_04645	COG1522	sequence-specific DNA binding
NJ8700_04650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NJ8700_04665	COG2932	Transcriptional regulator
NJ8700_04675	COG2801	Transposase and inactivated derivatives
NJ8700_04680	COG0791	NLP P60 protein
NJ8700_04690	COG2890	protein-(glutamine-N5) methyltransferase activity
NJ8700_04700	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NJ8700_04705	COG3133	Outer membrane lipoprotein
NJ8700_04710	COG3102	Protein conserved in bacteria
NJ8700_04720	COG5339	Protein conserved in bacteria
NJ8700_04725	COG0443	Heat shock 70 kDa protein
NJ8700_04730	COG1403	HNH endonuclease
NJ8700_04735	COG0484	heat shock protein binding
NJ8700_04745	COG0626	cystathionine gamma-synthase activity
NJ8700_04750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NJ8700_04770	COG0305	Participates in initiation and elongation during chromosome replication
NJ8700_04835	COG0629	single-stranded DNA binding
NJ8700_04890	COG3219	Protein conserved in bacteria
NJ8700_04895	COG3220	belongs to the UPF0276 family
NJ8700_04905	COG2259	Doxx family
NJ8700_04965	COG1858	cytochrome C peroxidase
NJ8700_04970	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NJ8700_04975	COG0318	PFAM AMP-dependent synthetase and ligase
NJ8700_04980	COG3065	identical protein binding
NJ8700_04985	COG1214	PFAM Peptidase M22, glycoprotease
NJ8700_04990	COG1199	ATP-dependent helicase activity
NJ8700_04995	COG0676	glucose-6-phosphate 1-epimerase activity
NJ8700_05005	COG1174	glycine betaine transport
NJ8700_05010	COG0517	IMP dehydrogenase activity
NJ8700_05010	COG1125	glycine betaine transport
NJ8700_05020	COG3118	belongs to the thioredoxin family
NJ8700_05025	COG0492	ferredoxin-NADP+ reductase activity
NJ8700_05030	COG4988	ABC transporter
NJ8700_05035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NJ8700_05040	COG1946	Acyl-CoA thioesterase
NJ8700_05050	COG0515	serine threonine protein kinase
NJ8700_05065	COG1216	Glycosyl transferase, family 2
NJ8700_05075	COG3306	glycosyltransferase involved in LPS biosynthesis
NJ8700_05085	COG5039	Polysaccharide pyruvyl transferase
NJ8700_05090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NJ8700_05095	COG1793	dna ligase
NJ8700_05105	COG0210	DNA helicase
NJ8700_05110	COG2610	gluconate transmembrane transporter activity
NJ8700_05115	COG3265	gluconokinase activity
NJ8700_05120	COG1609	Transcriptional regulator
NJ8700_05140	COG0437	4 iron, 4 sulfur cluster binding
NJ8700_05145	COG2864	formate dehydrogenase
NJ8700_05150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NJ8700_05155	COG4149	molybdate abc transporter
NJ8700_05160	COG0725	ABC transporter, periplasmic molybdate-binding protein
NJ8700_05165	COG2005	Transcriptional regulator
NJ8700_05175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NJ8700_05180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NJ8700_05180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NJ8700_05185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NJ8700_05195	COG0583	DNA-binding transcription factor activity
NJ8700_05200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NJ8700_05210	COG1438	arginine binding
NJ8700_05215	COG1090	epimerase
NJ8700_05220	COG4657	Part of a membrane complex involved in electron transport
NJ8700_05230	COG4656	Part of a membrane complex involved in electron transport
NJ8700_05250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NJ8700_05255	COG0733	neurotransmitter:sodium symporter activity
NJ8700_05260	COG3958	Transketolase
NJ8700_05265	COG3959	Transketolase, thiamine diphosphate binding domain
NJ8700_05290	COG1346	cytolysis
NJ8700_05300	COG0425	Belongs to the sulfur carrier protein TusA family
NJ8700_05305	COG2391	methyltransferase activity
NJ8700_05315	COG1525	nuclease
NJ8700_05320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NJ8700_05325	COG2166	iron-sulfur cluster assembly
NJ8700_05330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NJ8700_05330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NJ8700_05335	COG1560	Kdo2-lipid A biosynthetic process
NJ8700_05340	COG3381	protein complex oligomerization
NJ8700_05345	COG2249	NAD(P)H dehydrogenase (quinone) activity
NJ8700_05355	COG0330	HflC and HflK could
NJ8700_05360	COG0737	Belongs to the 5'-nucleotidase family
NJ8700_05365	COG1629	transport
NJ8700_05365	COG4771	TonB-dependent receptor
NJ8700_05370	COG4607	ABC-type enterochelin transport system periplasmic component
NJ8700_05375	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJ8700_05380	COG4605	iron ion homeostasis
NJ8700_05385	COG4604	ABC transporter, ATP-binding protein
NJ8700_05395	COG3383	formate dehydrogenase (NAD+) activity
NJ8700_05400	COG3383	formate dehydrogenase (NAD+) activity
NJ8700_05410	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NJ8700_05420	COG3260	NADH ubiquinone oxidoreductase 20
NJ8700_05430	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
NJ8700_05430	COG3261	NADH dehydrogenase
NJ8700_05435	COG0651	ATP synthesis coupled electron transport
NJ8700_05440	COG4237	Hydrogenase 4 membrane
NJ8700_05445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NJ8700_05450	COG0650	Formate hydrogenlyase subunit 4
NJ8700_05455	COG0651	ATP synthesis coupled electron transport
NJ8700_05460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NJ8700_05465	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
NJ8700_05470	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NJ8700_05490	COG0309	Hydrogenase expression formation protein (HypE)
NJ8700_05495	COG0409	Hydrogenase expression formation protein
NJ8700_05500	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NJ8700_05505	COG1122	ATPase activity
NJ8700_05510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NJ8700_05515	COG0310	cobalt ion transport
NJ8700_05520	COG0310	cobalt ion transport
NJ8700_05525	COG5266	PFAM Nickel transport complex, NikM subunit, transmembrane
NJ8700_05530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NJ8700_05535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NJ8700_05540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NJ8700_05545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NJ8700_05600	COG1840	ABC-type Fe3 transport system, periplasmic component
NJ8700_05605	COG1840	ABC-type Fe3 transport system, periplasmic component
NJ8700_05630	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NJ8700_05635	COG1959	2 iron, 2 sulfur cluster binding
NJ8700_05645	COG0822	iron-sulfur transferase activity
NJ8700_05655	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NJ8700_05660	COG0443	Heat shock 70 kDa protein
NJ8700_05665	COG0633	Ferredoxin
NJ8700_05670	COG2975	iron-sulfur cluster assembly
NJ8700_05675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJ8700_05675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NJ8700_05680	COG0489	protein tyrosine kinase activity
NJ8700_05685	COG3683	transport system, periplasmic component
NJ8700_05690	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
NJ8700_05705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NJ8700_05710	COG0488	(ABC) transporter
NJ8700_05725	COG0187	DNA topoisomerase II activity
NJ8700_05730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NJ8700_05735	COG0783	Belongs to the Dps family
NJ8700_05740	COG1566	PFAM secretion protein HlyD family protein
NJ8700_05745	COG2814	Major facilitator Superfamily
NJ8700_05750	COG1840	ABC-type Fe3 transport system, periplasmic component
NJ8700_05760	COG3550	peptidyl-serine autophosphorylation
NJ8700_05780	COG2927	DNA polymerase III (CHI subunit)
NJ8700_05785	COG0114	fumarate hydratase activity
NJ8700_05790	COG2268	Band 7 protein
NJ8700_05805	COG0778	Nitroreductase
NJ8700_05810	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NJ8700_05820	COG0814	amino acid
NJ8700_05830	COG0235	Class ii aldolase
NJ8700_05835	COG3623	hexulose-6-phosphate isomerase
NJ8700_05855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJ8700_05860	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
NJ8700_05890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NJ8700_05895	COG2017	converts alpha-aldose to the beta-anomer
NJ8700_05900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NJ8700_05905	COG1085	galactose-1-phosphate uridylyltransferase
NJ8700_05910	COG1609	Transcriptional regulator
NJ8700_05915	COG1879	ABC-type sugar transport system periplasmic component
NJ8700_05925	COG4211	Belongs to the binding-protein-dependent transport system permease family
NJ8700_05930	COG2198	Histidine kinase
NJ8700_05930	COG5002	protein histidine kinase activity
NJ8700_05930	COG0784	Response regulator, receiver
NJ8700_05935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NJ8700_05940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NJ8700_05940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NJ8700_05950	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NJ8700_05960	COG0497	DNA recombination
NJ8700_05970	COG2917	probably involved in intracellular septation
NJ8700_05975	COG1607	acyl-coa hydrolase
NJ8700_05980	COG2350	Protein conserved in bacteria
NJ8700_05985	COG0741	lytic transglycosylase activity
NJ8700_05995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NJ8700_06015	COG4133	protoheme IX ABC transporter activity
NJ8700_06030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NJ8700_06035	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NJ8700_06045	COG1408	metallophosphoesterase
NJ8700_06050	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
NJ8700_06055	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJ8700_06060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NJ8700_06065	COG1120	ATPase activity
NJ8700_06075	COG1053	succinate dehydrogenase
NJ8700_06080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NJ8700_06090	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NJ8700_06100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NJ8700_06105	COG0343	queuine tRNA-ribosyltransferase activity
NJ8700_06115	COG3945	hemerythrin HHE cation binding domain
NJ8700_06125	COG1862	Preprotein translocase
NJ8700_06130	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NJ8700_06135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NJ8700_06145	COG1454	alcohol dehydrogenase
NJ8700_06145	COG1012	belongs to the aldehyde dehydrogenase family
NJ8700_06150	COG0673	inositol 2-dehydrogenase activity
NJ8700_06160	COG2271	Major facilitator Superfamily
NJ8700_06170	COG3718	enzyme involved in inositol metabolism
NJ8700_06175	COG1737	Transcriptional regulator
NJ8700_06180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NJ8700_06185	COG3962	Belongs to the TPP enzyme family
NJ8700_06195	COG0673	inositol 2-dehydrogenase activity
NJ8700_06225	COG0151	Belongs to the GarS family
NJ8700_06230	COG0138	bifunctional purine biosynthesis protein purh
NJ8700_06240	COG2813	Specifically methylates the guanine in position
NJ8700_06245	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
NJ8700_06250	COG0456	acetyltransferase
NJ8700_06255	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NJ8700_06270	COG4795	General secretion pathway protein
NJ8700_06275	COG2165	general secretion pathway protein
NJ8700_06305	COG3064	Membrane
NJ8700_06310	COG0848	biopolymer transport protein
NJ8700_06315	COG0811	peptide transport
NJ8700_06320	COG0824	Thioesterase
NJ8700_06335	COG1294	oxidase, subunit
NJ8700_06340	COG1271	oxidase subunit
NJ8700_06355	COG0632	four-way junction helicase activity
NJ8700_06375	COG0494	nUDIX hydrolase
NJ8700_06380	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NJ8700_06385	COG1755	Isoprenylcysteine carboxyl methyltransferase
NJ8700_06400	COG2271	Major facilitator Superfamily
NJ8700_06415	COG0346	lactoylglutathione lyase activity
NJ8700_06420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NJ8700_06425	COG2056	Na+-H+ antiporter family
NJ8700_06450	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NJ8700_06460	COG0142	geranyltranstransferase activity
NJ8700_06475	COG0697	spore germination
NJ8700_06480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NJ8700_06495	COG4166	transmembrane transport
NJ8700_06500	COG0601	transmembrane transport
NJ8700_06505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NJ8700_06510	COG0444	Belongs to the ABC transporter superfamily
NJ8700_06515	COG4608	Belongs to the ABC transporter superfamily
NJ8700_06520	COG0745	RESPONSE REGULATOR receiver
NJ8700_06525	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NJ8700_06545	COG2259	Doxx family
NJ8700_06555	COG1530	ribonuclease E activity
NJ8700_06570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NJ8700_06575	COG0626	cystathionine gamma-synthase activity
NJ8700_06595	COG0527	aspartate kinase activity
NJ8700_06610	COG5295	Hep Hag repeat protein
NJ8700_06620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NJ8700_06630	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NJ8700_06635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NJ8700_06640	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NJ8700_06645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NJ8700_06645	COG0475	glutathione-regulated potassium exporter activity
NJ8700_06650	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
NJ8700_06680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NJ8700_06690	COG2867	negative regulation of translational initiation
NJ8700_06700	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NJ8700_06710	COG1758	RNA polymerase activity
NJ8700_06715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NJ8700_06725	COG3161	chorismate lyase activity
NJ8700_06730	COG2850	peptidyl-arginine hydroxylation
NJ8700_06740	COG1660	Displays ATPase and GTPase activities
NJ8700_06745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJ8700_06750	COG1137	ATPase activity
NJ8700_06755	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NJ8700_06760	COG3117	lipopolysaccharide transmembrane transporter activity
NJ8700_06765	COG1127	ABC transporter
NJ8700_06770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NJ8700_06775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NJ8700_06780	COG2854	intermembrane phospholipid transfer
NJ8700_06785	COG3113	response to antibiotic
NJ8700_06790	COG5007	Belongs to the BolA IbaG family
NJ8700_06800	COG3028	Belongs to the UPF0307 family
NJ8700_06805	COG0312	modulator of DNA gyrase
NJ8700_06810	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NJ8700_06815	COG1929	Belongs to the glycerate kinase type-1 family
NJ8700_06820	COG2610	gluconate transmembrane transporter activity
NJ8700_06825	COG3835	regulator
NJ8700_06855	COG0513	Belongs to the DEAD box helicase family
NJ8700_06860	COG4785	May be involved in cell division
NJ8700_06870	COG2731	YhcH YjgK YiaL family protein
NJ8700_06875	COG3023	N-Acetylmuramoyl-L-alanine amidase
NJ8700_06880	COG4969	Belongs to the N-Me-Phe pilin family
NJ8700_06885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NJ8700_06890	COG1459	type II secretion system
NJ8700_06895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NJ8700_06900	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NJ8700_06900	COG0237	dephospho-CoA kinase activity
NJ8700_06915	COG1115	amino acid carrier protein
NJ8700_06920	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NJ8700_06965	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NJ8700_06980	COG4145	pantothenate transmembrane transporter activity
NJ8700_06985	COG3924	membrane
NJ8700_06995	COG0084	hydrolase, TatD family'
NJ8700_07000	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NJ8700_07025	COG1686	Belongs to the peptidase S11 family
NJ8700_07030	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NJ8700_07030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NJ8700_07035	COG0772	Belongs to the SEDS family
NJ8700_07040	COG0768	penicillin binding
NJ8700_07050	COG0799	negative regulation of ribosome biogenesis
NJ8700_07055	COG0513	Belongs to the DEAD box helicase family
NJ8700_07060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NJ8700_07065	COG2814	Major facilitator Superfamily
NJ8700_07075	COG1028	Short-chain dehydrogenase reductase Sdr
NJ8700_07080	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NJ8700_07090	COG0416	fatty acid biosynthetic process
NJ8700_07095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NJ8700_07100	COG1399	metal-binding, possibly nucleic acid-binding protein
NJ8700_07110	COG2226	methyltransferase
NJ8700_07115	COG2830	Protein of unknown function (DUF452)
NJ8700_07125	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NJ8700_07130	COG0500	methyltransferase
NJ8700_07140	COG0671	phosphoesterase, PA-phosphatase related
NJ8700_07140	COG2453	phosphatase
NJ8700_07145	COG2267	carboxylic ester hydrolase activity
NJ8700_07150	COG0688	phosphatidylethanolamine metabolic process
NJ8700_07155	COG0545	Peptidyl-prolyl cis-trans isomerase
NJ8700_07165	COG2966	Psort location CytoplasmicMembrane, score
NJ8700_07170	COG3610	response to peptide
NJ8700_07175	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NJ8700_07180	COG1253	flavin adenine dinucleotide binding
NJ8700_07190	COG0084	hydrolase, TatD family'
NJ8700_07195	COG0470	DNA polymerase III
NJ8700_07200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NJ8700_07205	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NJ8700_07210	COG0628	permease
NJ8700_07215	COG0347	Belongs to the P(II) protein family
NJ8700_07220	COG0561	phosphatase activity
NJ8700_07255	COG0521	Mo-molybdopterin cofactor biosynthetic process
NJ8700_07260	COG4589	Belongs to the CDS family
NJ8700_07270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NJ8700_07275	COG0471	metal ion transport
NJ8700_07275	COG0490	domain, Protein
NJ8700_07295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NJ8700_07305	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
NJ8700_07320	COG0575	Belongs to the CDS family
NJ8700_07335	COG0233	cytoplasmic translational termination
NJ8700_07350	COG4178	(ABC) transporter
NJ8700_07365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NJ8700_07370	COG0066	3-isopropylmalate dehydratase activity
NJ8700_07375	COG2226	methyltransferase
NJ8700_07380	COG0814	amino acid
NJ8700_07390	COG4783	chaperone-mediated protein folding
NJ8700_07400	COG0848	biopolymer transport protein
NJ8700_07405	COG0811	peptide transport
NJ8700_07410	COG4536	flavin adenine dinucleotide binding
NJ8700_07415	COG4137	Cytochrome C assembly protein
NJ8700_07420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NJ8700_07460	COG0758	DNA mediated transformation
NJ8700_07465	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NJ8700_07485	COG2183	response to ionizing radiation
NJ8700_07490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NJ8700_07500	COG1595	DNA-templated transcription, initiation
NJ8700_07510	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NJ8700_07515	COG3071	HemY protein
NJ8700_07520	COG2959	enzyme of heme biosynthesis
NJ8700_07530	COG0181	hydroxymethylbilane synthase activity
NJ8700_07540	COG2197	response regulator
NJ8700_07545	COG0729	surface antigen
NJ8700_07550	COG2911	Protein conserved in bacteria
NJ8700_07555	COG0248	Ppx GppA phosphatase
NJ8700_07575	COG2991	Protein conserved in bacteria
NJ8700_07580	COG1477	protein flavinylation
NJ8700_07590	COG2871	sodium ion transport
NJ8700_07595	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NJ8700_07600	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NJ8700_07605	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NJ8700_07620	COG0271	Belongs to the BolA IbaG family
NJ8700_07625	COG3056	Lipoprotein
NJ8700_07650	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NJ8700_07655	COG1194	a g-specific adenine glycosylase
NJ8700_07665	COG3171	Protein conserved in bacteria
NJ8700_07670	COG1132	(ABC) transporter
NJ8700_07675	COG4977	sequence-specific DNA binding
NJ8700_07675	COG1917	Cupin 2, conserved barrel domain protein
NJ8700_07680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NJ8700_07685	COG0859	PFAM glycosyl transferase family 9
NJ8700_07705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NJ8700_07710	COG1840	ABC-type Fe3 transport system, periplasmic component
NJ8700_07725	COG1178	ABC-type Fe3 transport system permease component
NJ8700_07730	COG3842	ATPase activity
NJ8700_07740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NJ8700_07750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NJ8700_07755	COG1561	YicC-like family, N-terminal region
NJ8700_07760	COG0354	folic acid binding
NJ8700_07780	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NJ8700_07785	COG1381	Involved in DNA repair and RecF pathway recombination
NJ8700_07790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NJ8700_07795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NJ8700_07800	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NJ8700_07815	COG2177	Part of the ABC transporter FtsEX involved in
NJ8700_07820	COG2884	Cell division ATP-binding protein ftsE
NJ8700_07825	COG0552	protein localization to endoplasmic reticulum
NJ8700_07830	COG0742	ribosomal rna small subunit methyltransferase
NJ8700_07835	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJ8700_07835	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NJ8700_07840	COG3715	PTS system
NJ8700_07845	COG3716	PTS system mannose fructose sorbose family IID component
NJ8700_07850	COG0561	phosphatase activity
NJ8700_07860	COG2271	Major facilitator Superfamily
NJ8700_07865	COG1120	ATPase activity
NJ8700_07895	COG1215	transferase activity, transferring glycosyl groups
NJ8700_07900	COG0726	polysaccharide deacetylase
NJ8700_07900	COG1649	PFAM Uncharacterised BCR, COG1649
NJ8700_07915	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NJ8700_07920	COG2364	Membrane
NJ8700_07925	COG0859	PFAM glycosyl transferase family 9
NJ8700_07930	COG1027	Aspartate ammonia-lyase
NJ8700_07935	COG3030	protein affecting phage T7 exclusion by the F plasmid
NJ8700_07940	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NJ8700_07945	COG0459	protein refolding
NJ8700_07965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NJ8700_07970	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NJ8700_07980	COG1011	Hydrolase
NJ8700_08005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NJ8700_08065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NJ8700_08075	COG1028	Short-chain dehydrogenase reductase Sdr
NJ8700_08080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NJ8700_08085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NJ8700_08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NJ8700_08095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NJ8700_08100	COG3719	Belongs to the RNase T2 family
NJ8700_08110	COG0191	fructose-bisphosphate aldolase activity
NJ8700_08115	COG3307	-O-antigen
NJ8700_08120	COG2267	carboxylic ester hydrolase activity
NJ8700_08125	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NJ8700_08130	COG0561	phosphatase activity
NJ8700_08140	COG0028	Belongs to the TPP enzyme family
NJ8700_08160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NJ8700_08170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NJ8700_08185	COG1131	(ABC) transporter
NJ8700_08190	COG0842	Transport permease protein
NJ8700_08250	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NJ8700_08255	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NJ8700_08265	COG2960	long-chain fatty acid transporting porin activity
NJ8700_08270	COG3172	ATPase kinase involved in NAD metabolism
NJ8700_08275	COG2129	metallophosphoesterase
NJ8700_08280	COG0814	amino acid
NJ8700_08285	COG1555	photosystem II stabilization
NJ8700_08305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NJ8700_08310	COG0561	phosphatase activity
NJ8700_08315	COG1040	competence protein
NJ8700_08335	COG0107	imidazoleglycerol-phosphate synthase activity
NJ8700_08350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NJ8700_08360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NJ8700_08360	COG0131	Imidazoleglycerol-phosphate dehydratase
NJ8700_08365	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NJ8700_08370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NJ8700_08375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NJ8700_08380	COG1114	Component of the transport system for branched-chain amino acids
NJ8700_08415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NJ8700_08425	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NJ8700_08440	COG0589	response to stress
NJ8700_08445	COG3956	TIGRFAM MazG family protein
NJ8700_08450	COG0402	S-adenosylhomocysteine deaminase activity
NJ8700_08455	COG3083	sulfuric ester hydrolase activity
NJ8700_08470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NJ8700_08475	COG0745	RESPONSE REGULATOR receiver
NJ8700_08480	COG2205	protein histidine kinase activity
NJ8700_08485	COG0786	glutamate:sodium symporter activity
NJ8700_08500	COG3012	SEC-C Motif Domain Protein
NJ8700_08505	COG2258	MOSC domain
NJ8700_08510	COG0433	COG0433 Predicted ATPase
NJ8700_08520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NJ8700_08525	COG1349	DNA-binding transcription factor activity
NJ8700_08535	COG3068	Protein conserved in bacteria
NJ8700_08540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NJ8700_08560	COG0222	ribosome binding
NJ8700_08565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NJ8700_08585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NJ8700_08600	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
NJ8700_08675	COG0582	viral genome integration into host DNA
NJ8700_08685	COG3177	Filamentation induced by cAMP protein fic
NJ8700_08705	COG0513	Belongs to the DEAD box helicase family
NJ8700_08715	COG3201	nicotinamide mononucleotide transporter
NJ8700_08725	COG0564	pseudouridine synthase activity
NJ8700_08795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NJ8700_08820	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NJ8700_08820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NJ8700_08820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NJ8700_08825	COG1105	Belongs to the carbohydrate kinase PfkB family
NJ8700_08830	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJ8700_08830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NJ8700_08840	COG0746	molybdenum cofactor guanylyltransferase activity
NJ8700_08845	COG3084	Protein conserved in bacteria
NJ8700_08850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NJ8700_08855	COG3085	chromosome segregation
NJ8700_08965	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NJ8700_08975	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NJ8700_08995	COG0754	glutathionylspermidine amidase activity
NJ8700_09005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJ8700_09005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NJ8700_09015	COG5645	(Lipo)protein
NJ8700_09020	COG0210	DNA helicase
NJ8700_09045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NJ8700_09050	COG0110	maltose O-acetyltransferase activity
NJ8700_09055	COG1238	metal cluster binding
NJ8700_09065	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NJ8700_09090	COG1349	DNA-binding transcription factor activity
NJ8700_09095	COG0606	chelatase, subunit chli
NJ8700_09130	COG2861	carbohydrate metabolic process
NJ8700_09135	COG4942	peptidase
NJ8700_09140	COG2354	Protein conserved in bacteria
NJ8700_09170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NJ8700_09195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NJ8700_09205	COG2095	MarC family integral membrane protein
NJ8700_09235	COG0546	phosphoglycolate phosphatase activity
NJ8700_09240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NJ8700_09260	COG0585	pseudouridine synthase activity
NJ8700_09270	COG1238	metal cluster binding
NJ8700_09280	COG1388	LysM domain
NJ8700_09280	COG4942	peptidase
NJ8700_09300	COG2814	Major facilitator Superfamily
NJ8700_09305	COG1763	Mo-molybdopterin cofactor biosynthetic process
NJ8700_09310	COG3086	response to oxidative stress
NJ8700_09315	COG3026	antisigma factor binding
NJ8700_09320	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NJ8700_09325	COG1595	DNA-templated transcription, initiation
NJ8700_09340	COG0442	prolyl-tRNA aminoacylation
NJ8700_09345	COG1921	L-seryl-tRNASec selenium transferase activity
NJ8700_09350	COG3276	selenocysteine insertion sequence binding
NJ8700_09360	COG1902	pentaerythritol trinitrate reductase activity
NJ8700_09365	COG1285	pathogenesis
NJ8700_09375	COG0733	neurotransmitter:sodium symporter activity
NJ8700_09390	COG1132	(ABC) transporter
NJ8700_09395	COG4988	ABC transporter
NJ8700_09400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NJ8700_09405	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NJ8700_09410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NJ8700_09420	COG1045	serine acetyltransferase
NJ8700_09430	COG1494	fructose-1,6-bisphosphatase
NJ8700_09435	COG3074	FtsZ-dependent cytokinesis
NJ8700_09440	COG0716	FMN binding
NJ8700_09450	COG0357	Ribosomal RNA small subunit methyltransferase G
NJ8700_09455	COG3312	ion transport
NJ8700_09470	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NJ8700_09475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NJ8700_09485	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NJ8700_09505	COG0859	PFAM glycosyl transferase family 9
NJ8700_09520	COG0737	Belongs to the 5'-nucleotidase family
NJ8700_09525	COG1309	transcriptional regulator
NJ8700_09530	COG0583	DNA-binding transcription factor activity
NJ8700_09535	COG0678	peroxiredoxin activity
NJ8700_09535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NJ8700_09540	COG0754	glutathionylspermidine amidase activity
NJ8700_09545	COG3005	denitrification pathway
NJ8700_09550	COG3043	anaerobic respiration
NJ8700_09555	COG0348	domain, Protein
NJ8700_09560	COG0437	4 iron, 4 sulfur cluster binding
NJ8700_09565	COG0243	molybdopterin cofactor binding
NJ8700_09570	COG3062	negative regulation of establishment of protein localization
NJ8700_09575	COG3850	Histidine kinase
NJ8700_09590	COG1275	C4-dicarboxylate transporter malic acid transport protein
NJ8700_09595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NJ8700_09600	COG2195	Cleaves the N-terminal amino acid of tripeptides
NJ8700_09615	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NJ8700_09620	COG2818	Glycosylase
NJ8700_09625	COG3477	response to acidic pH
NJ8700_09630	COG0019	diaminopimelate decarboxylase activity
NJ8700_09645	COG0514	ATP-dependent DNA helicase (RecQ)
NJ8700_09650	COG0187	DNA topoisomerase II activity
NJ8700_09655	COG1072	(Pantothenic acid kinase))
NJ8700_09690	COG1126	abc transporter atp-binding protein
NJ8700_09695	COG0765	amino acid transport
NJ8700_09700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NJ8700_09705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NJ8700_09715	COG0545	Peptidyl-prolyl cis-trans isomerase
NJ8700_09720	COG2964	Protein conserved in bacteria
NJ8700_09725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NJ8700_09735	COG2168	tRNA wobble position uridine thiolation
NJ8700_09745	COG0840	transmembrane signaling receptor activity
NJ8700_09750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NJ8700_09775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NJ8700_09790	COG0702	epimerase
NJ8700_09795	COG1733	regulation of RNA biosynthetic process
NJ8700_09800	COG0752	glycyl-tRNA synthetase alpha subunit
NJ8700_09820	COG0751	glycine-tRNA ligase activity
NJ8700_09830	COG0805	protein transport
NJ8700_09850	COG3165	ubiquinone biosynthetic process from chorismate
NJ8700_09865	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NJ8700_09870	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NJ8700_09875	COG1011	Hydrolase
NJ8700_09880	COG0494	nUDIX hydrolase
NJ8700_09885	COG1917	Cupin 2, conserved barrel domain protein
NJ8700_09885	COG4977	sequence-specific DNA binding
NJ8700_09890	COG3059	membrane
NJ8700_09895	COG1297	OPT oligopeptide transporter protein
NJ8700_09905	COG1218	3'(2'),5'-bisphosphate nucleotidase
NJ8700_09910	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NJ8700_09915	COG0363	glucosamine-6-phosphate deaminase activity
NJ8700_09975	COG0747	negative chemotaxis
NJ8700_09980	COG2853	Lipoprotein
NJ8700_09995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NJ8700_10055	COG3501	Rhs element vgr protein
NJ8700_10075	COG2990	Protein conserved in bacteria
NJ8700_10080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NJ8700_10100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NJ8700_10145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NJ8700_10145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NJ8700_10150	COG0569	domain protein
NJ8700_10155	COG1970	mechanosensitive ion channel activity
NJ8700_10160	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NJ8700_10175	COG2841	Protein conserved in bacteria
NJ8700_10180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NJ8700_10185	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
NJ8700_10190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NJ8700_10195	COG3036	rescue of stalled ribosome
NJ8700_10205	COG1393	Belongs to the ArsC family
NJ8700_10215	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NJ8700_10220	COG1522	sequence-specific DNA binding
NJ8700_10230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NJ8700_10235	COG0038	chloride channel
NJ8700_10245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NJ8700_10250	COG0549	Belongs to the carbamate kinase family
NJ8700_10255	COG1288	antiporter activity
NJ8700_10260	COG1522	sequence-specific DNA binding
NJ8700_10265	COG0051	transcription antitermination factor activity, RNA binding
NJ8700_10270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NJ8700_10275	COG0088	Forms part of the polypeptide exit tunnel
NJ8700_10280	COG0089	rRNA binding
NJ8700_10285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NJ8700_10290	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NJ8700_10295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NJ8700_10300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NJ8700_10305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NJ8700_10315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NJ8700_10330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NJ8700_10350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NJ8700_10360	COG1841	ribosomal large subunit assembly
NJ8700_10370	COG0201	protein transport
NJ8700_10385	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NJ8700_10400	COG0463	Glycosyl transferase, family 2
NJ8700_10405	COG1519	Transferase
NJ8700_10410	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NJ8700_10420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NJ8700_10425	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NJ8700_10430	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NJ8700_10450	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
NJ8700_10455	COG1466	dna polymerase III delta subunit
NJ8700_10465	COG0494	nUDIX hydrolase
NJ8700_10480	COG4701	Protein of unknown function (DUF721)
NJ8700_10485	COG0789	Transcriptional regulator
NJ8700_10490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NJ8700_10520	COG0583	DNA-binding transcription factor activity
NJ8700_10560	COG3384	dioxygenase
NJ8700_10565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NJ8700_10570	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NJ8700_10575	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NJ8700_10585	COG4796	Type ii and iii secretion system protein
NJ8700_10605	COG4972	Pilus assembly protein
NJ8700_10610	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NJ8700_10615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NJ8700_10620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NJ8700_10645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NJ8700_10665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NJ8700_10685	COG3306	glycosyltransferase involved in LPS biosynthesis
NJ8700_10695	COG3306	glycosyltransferase involved in LPS biosynthesis
NJ8700_10705	COG4750	Nucleotidyl transferase
NJ8700_10720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NJ8700_10725	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NJ8700_10730	COG1309	transcriptional regulator
NJ8700_10735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NJ8700_10740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NJ8700_10745	COG0500	methyltransferase
NJ8700_10755	COG0762	integral membrane protein
NJ8700_10765	COG0778	Nitroreductase
NJ8700_10770	COG1368	sulfuric ester hydrolase activity
NJ8700_10795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NJ8700_10810	COG0006	proline dipeptidase activity
NJ8700_10820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NJ8700_10840	COG0335	large ribosomal subunit rRNA binding
NJ8700_10845	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NJ8700_10850	COG1792	Involved in formation and maintenance of cell shape
NJ8700_10855	COG1077	Cell shape determining protein MreB Mrl
NJ8700_10865	COG0557	exoribonuclease II activity
NJ8700_10875	COG2271	Major facilitator Superfamily
NJ8700_10880	COG0584	glycerophosphoryl diester phosphodiesterase
NJ8700_10895	COG0583	DNA-binding transcription factor activity
NJ8700_10900	COG2962	Rard protein
NJ8700_10915	COG0551	DNA topoisomerase type I activity
NJ8700_10935	COG0705	Rhomboid family
NJ8700_10940	COG1349	DNA-binding transcription factor activity
NJ8700_10945	COG1629	transport
NJ8700_10945	COG4206	TonB-dependent receptor
NJ8700_11000	COG5566	PFAM Mor transcription activator
NJ8700_11005	COG0582	viral genome integration into host DNA
NJ8700_11015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NJ8700_11025	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NJ8700_11035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NJ8700_11055	COG3115	cell septum assembly
NJ8700_11065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NJ8700_11070	COG1573	uracil-dna glycosylase
NJ8700_11075	COG0012	GTP binding
NJ8700_11080	COG0193	aminoacyl-tRNA hydrolase activity
NJ8700_11090	COG0560	Phosphoserine phosphatase
NJ8700_11115	COG0728	peptidoglycan biosynthetic process
NJ8700_11120	COG0196	riboflavin kinase activity
NJ8700_11140	COG1555	photosystem II stabilization
NJ8700_11145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NJ8700_11155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NJ8700_11160	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NJ8700_11165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NJ8700_11170	COG2321	neutral zinc metallopeptidase
NJ8700_11175	COG1652	LysM domain
NJ8700_11185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NJ8700_11190	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NJ8700_11200	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NJ8700_11215	COG0436	Aminotransferase
NJ8700_11225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NJ8700_11230	COG2267	carboxylic ester hydrolase activity
NJ8700_11240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NJ8700_11245	COG3091	SprT-like family
NJ8700_11250	COG0814	amino acid
NJ8700_11255	COG1760	l-serine dehydratase