locus-tag	class	description
F3P66_00010	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3P66_00015	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F3P66_00025	COG0237	dephospho-CoA kinase activity
F3P66_00030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3P66_00035	COG0424	maF-like protein
F3P66_00040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F3P66_00050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F3P66_00055	COG1981	membrane
F3P66_00060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3P66_00065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F3P66_00070	COG0445	tRNA wobble uridine modification
F3P66_00075	COG0357	Ribosomal RNA small subunit methyltransferase G
F3P66_00095	COG0501	Belongs to the peptidase M48B family
F3P66_00100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3P66_00100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3P66_00110	COG0138	bifunctional purine biosynthesis protein purh
F3P66_00115	COG2721	sulfolactate sulfo-lyase activity
F3P66_00120	COG2186	Transcriptional regulator
F3P66_00125	COG1129	ABC transporter
F3P66_00130	COG4214	carbohydrate transport
F3P66_00150	COG1063	alcohol dehydrogenase
F3P66_00155	COG0246	Mannitol dehydrogenase
F3P66_00160	COG3254	rhamnose metabolic process
F3P66_00165	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_00180	COG1492	cobalamin metabolic process
F3P66_00245	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
F3P66_00250	COG1648	precorrin-2 dehydrogenase activity
F3P66_00250	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3P66_00255	COG1797	cobyrinic acid a,c-diamide synthase activity
F3P66_00260	COG1858	cytochrome C peroxidase
F3P66_00265	COG0473	3-isopropylmalate dehydrogenase activity
F3P66_00270	COG0066	3-isopropylmalate dehydratase activity
F3P66_00295	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3P66_00300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F3P66_00315	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F3P66_00320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F3P66_00325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F3P66_00330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F3P66_00335	COG0799	negative regulation of ribosome biogenesis
F3P66_00340	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F3P66_00350	COG0793	Belongs to the peptidase S41A family
F3P66_00360	COG0494	nUDIX hydrolase
F3P66_00375	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_00390	COG2270	Major facilitator Superfamily
F3P66_00395	COG2902	Dehydrogenase
F3P66_00400	COG1329	Transcriptional regulator
F3P66_00410	COG0745	RESPONSE REGULATOR receiver
F3P66_00425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3P66_00430	COG1674	ftsk spoiiie
F3P66_00435	COG0004	ammonium transporteR
F3P66_00440	COG0347	Belongs to the P(II) protein family
F3P66_00445	COG1946	Acyl-CoA thioesterase
F3P66_00450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P66_00470	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3P66_00485	COG0495	leucyl-tRNA aminoacylation
F3P66_00490	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3P66_00500	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3P66_00505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3P66_00510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3P66_00515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3P66_00525	COG2186	Transcriptional regulator
F3P66_00530	COG0277	FAD linked oxidase domain protein
F3P66_00535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P66_00540	COG2084	Dehydrogenase
F3P66_00545	COG0129	dihydroxy-acid dehydratase activity
F3P66_00555	COG0579	oxidoreductase
F3P66_00565	COG1473	amidohydrolase
F3P66_00570	COG3459	Glycosyltransferase 36 associated
F3P66_00580	COG1132	(ABC) transporter
F3P66_00585	COG2197	response regulator
F3P66_00590	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F3P66_00595	COG1349	DNA-binding transcription factor activity
F3P66_00600	COG2223	nitrite transmembrane transporter activity
F3P66_00605	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F3P66_00610	COG2885	chlorophyll binding
F3P66_00615	COG0142	geranyltranstransferase activity
F3P66_00620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3P66_00630	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
F3P66_00640	COG0488	(ABC) transporter
F3P66_00660	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F3P66_00695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_00700	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3P66_00710	COG0335	large ribosomal subunit rRNA binding
F3P66_00720	COG0336	Belongs to the RNA methyltransferase TrmD family
F3P66_00725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F3P66_00730	COG0228	four-way junction DNA binding
F3P66_00735	COG1605	Chorismate mutase
F3P66_00735	COG0287	Prephenate dehydrogenase
F3P66_00740	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3P66_00755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F3P66_00760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3P66_00765	COG0552	protein localization to endoplasmic reticulum
F3P66_00770	COG2917	probably involved in intracellular septation
F3P66_00795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3P66_00800	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3P66_00805	COG4133	protoheme IX ABC transporter activity
F3P66_00810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3P66_00825	COG0670	Belongs to the BI1 family
F3P66_00835	COG4181	ATPase activity
F3P66_00845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3P66_00850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3P66_00855	COG2154	pterin-4-alpha-carbinolamine dehydratase
F3P66_00870	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F3P66_00880	COG4120	Belongs to the binding-protein-dependent transport system permease family
F3P66_00885	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F3P66_00890	COG1280	lysine exporter protein (LysE YggA)
F3P66_00900	COG0137	argininosuccinate synthase activity
F3P66_00910	COG1846	Transcriptional regulator
F3P66_00915	COG0339	signal peptide processing
F3P66_00920	COG1217	gtp-binding protein TYPA
F3P66_00935	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3P66_00940	COG1872	DUF167
F3P66_00975	COG0181	hydroxymethylbilane synthase activity
F3P66_00980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F3P66_00985	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F3P66_01000	COG2264	protein methyltransferase activity
F3P66_01035	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3P66_01040	COG0039	L-malate dehydrogenase activity
F3P66_01045	COG0045	succinate-CoA ligase (ADP-forming) activity
F3P66_01050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3P66_01070	COG1280	lysine exporter protein (LysE YggA)
F3P66_01095	COG4974	Belongs to the 'phage' integrase family
F3P66_01110	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3P66_01115	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F3P66_01120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F3P66_01125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F3P66_01130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F3P66_01140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3P66_01150	COG0835	chemotaxis
F3P66_01160	COG0729	surface antigen
F3P66_01170	COG0156	8-amino-7-oxononanoate synthase activity
F3P66_01175	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F3P66_01180	COG0671	phosphoesterase, PA-phosphatase related
F3P66_01190	COG1940	carbohydrate kinase activity
F3P66_01195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3P66_01200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3P66_01205	COG2188	Transcriptional regulator
F3P66_01220	COG1175	transmembrane transport
F3P66_01225	COG0395	ABC-type sugar transport system, permease component
F3P66_01235	COG3842	ATPase activity
F3P66_01245	COG1737	Transcriptional regulator
F3P66_01250	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_01270	COG3142	Participates in the control of copper homeostasis
F3P66_01275	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3P66_01280	COG0438	transferase activity, transferring glycosyl groups
F3P66_01290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_01295	COG0601	transmembrane transport
F3P66_01300	COG4166	transmembrane transport
F3P66_01320	COG0438	transferase activity, transferring glycosyl groups
F3P66_01345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3P66_01370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3P66_01380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3P66_01385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F3P66_01400	COG2022	thiamine diphosphate biosynthetic process
F3P66_01405	COG3191	aminopeptidase activity
F3P66_01415	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F3P66_01420	COG4149	molybdate abc transporter
F3P66_01425	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3P66_01430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_01435	COG0583	DNA-binding transcription factor activity
F3P66_01450	COG1509	lysine 2,3-aminomutase activity
F3P66_01460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F3P66_01470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3P66_01475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_01485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3P66_01530	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P66_01530	COG1902	pentaerythritol trinitrate reductase activity
F3P66_01540	COG0745	RESPONSE REGULATOR receiver
F3P66_01570	COG1960	acyl-CoA dehydrogenase activity
F3P66_01615	COG0392	lysyltransferase activity
F3P66_01615	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F3P66_01635	COG0601	transmembrane transport
F3P66_01640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_01645	COG0444	Belongs to the ABC transporter superfamily
F3P66_01650	COG4608	Belongs to the ABC transporter superfamily
F3P66_01665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3P66_01675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_01680	COG3842	ATPase activity
F3P66_01685	COG0395	ABC-type sugar transport system, permease component
F3P66_01690	COG1175	transmembrane transport
F3P66_01705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_01720	COG1335	isochorismatase
F3P66_01725	COG0251	oxidation-reduction process
F3P66_01730	COG2267	carboxylic ester hydrolase activity
F3P66_01735	COG0778	Nitroreductase
F3P66_01740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P66_01745	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F3P66_01765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3P66_01775	COG0288	reversible hydration of carbon dioxide
F3P66_01780	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
F3P66_01785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3P66_01805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_01810	COG0657	acetylesterase activity
F3P66_01815	COG0583	DNA-binding transcription factor activity
F3P66_01830	COG0783	Belongs to the Dps family
F3P66_01835	COG4604	ABC transporter, ATP-binding protein
F3P66_01840	COG4605	iron ion homeostasis
F3P66_01845	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P66_01885	COG2205	protein histidine kinase activity
F3P66_01905	COG3721	Heme iron utilization protein
F3P66_01915	COG4558	Periplasmic binding protein
F3P66_01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P66_01925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F3P66_01930	COG2832	Protein of unknown function (DUF454)
F3P66_01940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F3P66_01950	COG0346	lactoylglutathione lyase activity
F3P66_01980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F3P66_01995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3P66_02005	COG0564	pseudouridine synthase activity
F3P66_02090	COG1218	3'(2'),5'-bisphosphate nucleotidase
F3P66_02140	COG0784	Response regulator, receiver
F3P66_02140	COG2198	Histidine kinase
F3P66_02140	COG5002	protein histidine kinase activity
F3P66_02145	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_02150	COG0174	glutamine synthetase
F3P66_02170	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3P66_02200	COG0829	nickel cation binding
F3P66_02205	COG0831	urea catabolic process
F3P66_02210	COG3813	Protein conserved in bacteria
F3P66_02215	COG0832	Belongs to the urease beta subunit family
F3P66_02225	COG3755	Protein conserved in bacteria
F3P66_02230	COG1442	glycosyl transferase family 8
F3P66_02235	COG0804	urea catabolic process
F3P66_02250	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F3P66_02255	COG0830	nickel cation binding
F3P66_02260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3P66_02300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_02305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_02320	COG0494	nUDIX hydrolase
F3P66_02335	COG1309	transcriptional regulator
F3P66_02355	COG2346	COG2346, Truncated hemoglobins
F3P66_02360	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3P66_02395	COG1215	transferase activity, transferring glycosyl groups
F3P66_02430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_02435	COG4215	(ABC) transporter
F3P66_02445	COG0646	methionine synthase
F3P66_02445	COG1410	methionine synthase
F3P66_02450	COG2814	Major facilitator Superfamily
F3P66_02455	COG0840	transmembrane signaling receptor activity
F3P66_02465	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3P66_02510	COG4213	ABC transporter substrate-binding protein
F3P66_02515	COG1129	ABC transporter
F3P66_02520	COG4214	carbohydrate transport
F3P66_02535	COG0456	acetyltransferase
F3P66_02550	COG1305	Transglutaminase-like
F3P66_02570	COG1376	ErfK ybiS ycfS ynhG family protein
F3P66_02575	COG2259	Doxx family
F3P66_02580	COG0697	spore germination
F3P66_02585	COG0513	Belongs to the DEAD box helicase family
F3P66_02595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_02595	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F3P66_02605	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3P66_02630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F3P66_02635	COG2351	hydroxyisourate hydrolase activity
F3P66_02645	COG1686	Belongs to the peptidase S11 family
F3P66_02650	COG1309	transcriptional regulator
F3P66_02660	COG1304	FMN binding
F3P66_02675	COG0402	S-adenosylhomocysteine deaminase activity
F3P66_02690	COG0583	DNA-binding transcription factor activity
F3P66_02715	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_02730	COG0024	Methionine aminopeptidase
F3P66_02740	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3P66_02760	COG1160	GTP binding
F3P66_02780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_02785	COG0366	Alpha amylase catalytic
F3P66_02800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3P66_02815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3P66_02815	COG0512	Glutamine amidotransferase of anthranilate synthase
F3P66_02830	COG2862	Uncharacterized protein family, UPF0114
F3P66_02850	COG1435	thymidine kinase activity
F3P66_02865	COG4175	Glycine betaine
F3P66_02890	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3P66_02895	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F3P66_02910	COG0740	serine-type endopeptidase activity
F3P66_02920	COG1595	DNA-templated transcription, initiation
F3P66_02935	COG3135	benzoate transporter
F3P66_02940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3P66_02955	COG0494	nUDIX hydrolase
F3P66_02960	COG0435	Glutathione S-transferase
F3P66_02970	COG0477	Major facilitator Superfamily
F3P66_02975	COG0454	-acetyltransferase
F3P66_02995	COG0714	Associated with various cellular activities
F3P66_03005	COG0494	nUDIX hydrolase
F3P66_03010	COG0617	tRNA 3'-terminal CCA addition
F3P66_03025	COG0408	coproporphyrinogen oxidase activity
F3P66_03040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3P66_03045	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3P66_03050	COG1132	(ABC) transporter
F3P66_03075	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3P66_03075	COG2857	Cytochrome c1
F3P66_03080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3P66_03100	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3P66_03110	COG0193	aminoacyl-tRNA hydrolase activity
F3P66_03120	COG5001	Diguanylate cyclase
F3P66_03125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F3P66_03130	COG3300	MHYT domain
F3P66_03130	COG5001	Diguanylate cyclase
F3P66_03135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F3P66_03140	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_03145	COG0840	transmembrane signaling receptor activity
F3P66_03160	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3P66_03170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3P66_03185	COG1496	oxidoreductase activity
F3P66_03195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F3P66_03215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3P66_03220	COG2205	protein histidine kinase activity
F3P66_03225	COG0745	RESPONSE REGULATOR receiver
F3P66_03230	COG1846	Transcriptional regulator
F3P66_03245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P66_03250	COG1278	Cold shock
F3P66_03270	COG2200	EAL domain
F3P66_03270	COG2199	diguanylate cyclase activity
F3P66_03275	COG0436	Aminotransferase
F3P66_03280	COG0387	Pfam Sodium calcium exchanger
F3P66_03315	COG1902	pentaerythritol trinitrate reductase activity
F3P66_03325	COG0583	DNA-binding transcription factor activity
F3P66_03330	COG0492	ferredoxin-NADP+ reductase activity
F3P66_03335	COG1522	sequence-specific DNA binding
F3P66_03345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3P66_03360	COG3706	GGDEF domain
F3P66_03370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3P66_03385	COG2321	neutral zinc metallopeptidase
F3P66_03405	COG0534	Mate efflux family protein
F3P66_03415	COG0505	Belongs to the CarA family
F3P66_03425	COG0358	DNA primase activity
F3P66_03430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3P66_03445	COG0432	Pfam Uncharacterised protein family UPF0047
F3P66_03455	COG2968	Membrane
F3P66_03515	COG3842	ATPase activity
F3P66_03550	COG0531	amino acid
F3P66_03555	COG0174	glutamine synthetase
F3P66_03570	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_03595	COG2814	Major facilitator Superfamily
F3P66_03615	COG0251	oxidation-reduction process
F3P66_03630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3P66_03635	COG2267	carboxylic ester hydrolase activity
F3P66_03645	COG2226	methyltransferase
F3P66_03665	COG4106	trans-aconitate 2-methyltransferase activity
F3P66_03695	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3P66_03730	COG0754	glutathionylspermidine amidase activity
F3P66_03740	COG3766	membrane
F3P66_03745	COG2001	Belongs to the MraZ family
F3P66_03750	COG0275	rRNA processing
F3P66_03765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3P66_03775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3P66_03780	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3P66_03790	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3P66_03795	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F3P66_03800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3P66_03805	COG5001	Diguanylate cyclase
F3P66_03805	COG3300	MHYT domain
F3P66_03810	COG0477	Major facilitator Superfamily
F3P66_03820	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F3P66_03825	COG0849	cell division
F3P66_03830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3P66_03840	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3P66_03845	COG0497	DNA recombination
F3P66_03850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3P66_03860	COG1247	-acetyltransferase
F3P66_03870	COG0583	DNA-binding transcription factor activity
F3P66_03875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3P66_03885	COG0835	chemotaxis
F3P66_03895	COG1999	signal sequence binding
F3P66_03900	COG2264	protein methyltransferase activity
F3P66_03910	COG0006	proline dipeptidase activity
F3P66_03930	COG1335	isochorismatase
F3P66_03985	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3P66_03990	COG0277	FAD linked oxidase domain protein
F3P66_04025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F3P66_04035	COG0330	HflC and HflK could
F3P66_04040	COG0330	HflC and HflK could
F3P66_04050	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_04060	COG0560	Phosphoserine phosphatase
F3P66_04060	COG3830	Belongs to the UPF0237 family
F3P66_04065	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F3P66_04075	COG0028	Belongs to the TPP enzyme family
F3P66_04080	COG0440	acetolactate synthase activity
F3P66_04095	COG0656	L-ascorbic acid biosynthetic process
F3P66_04125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3P66_04130	COG2197	response regulator
F3P66_04135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3P66_04140	COG1252	NADH dehydrogenase
F3P66_04145	COG1064	alcohol dehydrogenase
F3P66_04150	COG2207	Transcriptional regulator
F3P66_04160	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F3P66_04170	COG4115	mRNA cleavage
F3P66_04190	COG1840	ABC-type Fe3 transport system, periplasmic component
F3P66_04200	COG3842	ATPase activity
F3P66_04210	COG3706	GGDEF domain
F3P66_04225	COG0484	heat shock protein binding
F3P66_04245	COG2382	esterase
F3P66_04255	COG1733	regulation of RNA biosynthetic process
F3P66_04260	COG2910	NAD(P)H-binding
F3P66_04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3P66_04310	COG4251	negative regulation of phosphorylation
F3P66_04315	COG0784	Response regulator, receiver
F3P66_04320	COG2202	Pas domain
F3P66_04320	COG3920	Histidine kinase
F3P66_04325	COG0784	Response regulator, receiver
F3P66_04330	COG2205	protein histidine kinase activity
F3P66_04330	COG0784	Response regulator, receiver
F3P66_04330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_04330	COG2198	Histidine kinase
F3P66_04365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3P66_04385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3P66_04410	COG3895	Periplasmic Protein
F3P66_04425	COG0861	Integral membrane protein TerC family
F3P66_04430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3P66_04435	COG1086	Polysaccharide biosynthesis protein
F3P66_04445	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3P66_04455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F3P66_04460	COG0081	regulation of translation
F3P66_04465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F3P66_04470	COG0222	ribosome binding
F3P66_04475	COG0085	RNA polymerase activity
F3P66_04480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F3P66_04500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F3P66_04505	COG0049	tRNA binding
F3P66_04510	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F3P66_04515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3P66_04520	COG0051	transcription antitermination factor activity, RNA binding
F3P66_04525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F3P66_04530	COG0088	Forms part of the polypeptide exit tunnel
F3P66_04535	COG0089	rRNA binding
F3P66_04540	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F3P66_04545	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F3P66_04550	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F3P66_04555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F3P66_04560	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F3P66_04565	COG0255	Belongs to the universal ribosomal protein uL29 family
F3P66_04570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F3P66_04575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F3P66_04580	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F3P66_04585	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F3P66_04590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F3P66_04595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F3P66_04600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F3P66_04605	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F3P66_04610	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F3P66_04615	COG1841	ribosomal large subunit assembly
F3P66_04620	COG0200	Binds to the 23S rRNA
F3P66_04625	COG0201	protein transport
F3P66_04630	COG0563	adenylate kinase activity
F3P66_04635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F3P66_04640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F3P66_04645	COG0202	RNA polymerase activity
F3P66_04650	COG0203	ribosomal protein L17
F3P66_04655	COG3739	integral membrane protein
F3P66_04665	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F3P66_04670	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3P66_04675	COG0129	dihydroxy-acid dehydratase activity
F3P66_04690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3P66_04695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3P66_04735	COG0842	Transport permease protein
F3P66_04745	COG2390	Transcriptional regulator
F3P66_04750	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3P66_04755	COG3958	Transketolase
F3P66_04760	COG3959	Transketolase, thiamine diphosphate binding domain
F3P66_04765	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_04775	COG1129	ABC transporter
F3P66_04780	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_04790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3P66_04805	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F3P66_04810	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F3P66_04820	COG2205	protein histidine kinase activity
F3P66_04820	COG2202	Pas domain
F3P66_04830	COG1573	uracil-dna glycosylase
F3P66_04835	COG1522	sequence-specific DNA binding
F3P66_04840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_04850	COG5425	PFAM Usg family protein
F3P66_04860	COG4215	(ABC) transporter
F3P66_04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_04880	COG2313	pseudouridylate synthase activity
F3P66_04885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_04890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F3P66_04895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3P66_04910	COG0538	isocitrate dehydrogenase activity
F3P66_04920	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F3P66_04925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F3P66_04940	COG1280	lysine exporter protein (LysE YggA)
F3P66_04955	COG0861	Integral membrane protein TerC family
F3P66_04960	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F3P66_04965	COG2066	Belongs to the glutaminase family
F3P66_04970	COG0037	tRNA processing
F3P66_04975	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_04980	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_04985	COG2814	Major facilitator Superfamily
F3P66_04990	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F3P66_05010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3P66_05020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P66_05035	COG0047	phosphoribosylformylglycinamidine synthase activity
F3P66_05040	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3P66_05045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3P66_05055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3P66_05095	COG0513	Belongs to the DEAD box helicase family
F3P66_05100	COG0739	heme binding
F3P66_05105	COG2833	Protein of unknown function (DUF455)
F3P66_05110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3P66_05120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F3P66_05125	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F3P66_05130	COG2945	thiolester hydrolase activity
F3P66_05135	COG1104	cysteine desulfurase activity
F3P66_05140	COG0719	Fe-S assembly protein
F3P66_05145	COG0396	ATPase activity
F3P66_05150	COG0719	Fe-S assembly protein
F3P66_05155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3P66_05160	COG2151	metal-sulfur cluster biosynthetic enzyme
F3P66_05175	COG1136	(ABC) transporter
F3P66_05175	COG0577	efflux transmembrane transporter activity
F3P66_05180	COG0577	efflux transmembrane transporter activity
F3P66_05180	COG1136	(ABC) transporter
F3P66_05195	COG2267	carboxylic ester hydrolase activity
F3P66_05255	COG1278	Cold shock
F3P66_05295	COG0785	Cytochrome C biogenesis protein
F3P66_05300	COG0679	Auxin Efflux Carrier
F3P66_05305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P66_05310	COG1183	phosphatidylcholine synthase activity
F3P66_05315	COG3845	ABC transporter
F3P66_05320	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3P66_05325	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3P66_05335	COG2186	Transcriptional regulator
F3P66_05340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3P66_05345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3P66_05360	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3P66_05365	COG3668	Plasmid stabilization system
F3P66_05375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3P66_05385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3P66_05400	COG0697	spore germination
F3P66_05435	COG0347	Belongs to the P(II) protein family
F3P66_05440	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3P66_05440	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3P66_05455	COG0583	DNA-binding transcription factor activity
F3P66_05490	COG1760	l-serine dehydratase
F3P66_05525	COG0516	GMP reductase activity
F3P66_05525	COG0517	IMP dehydrogenase activity
F3P66_05530	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3P66_05535	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3P66_05540	COG0302	gtp cyclohydrolase
F3P66_05550	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F3P66_05560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F3P66_05575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P66_05600	COG0628	permease
F3P66_05605	COG1132	(ABC) transporter
F3P66_05615	COG1914	H( )-stimulated, divalent metal cation uptake system
F3P66_05630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3P66_05635	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F3P66_05640	COG0589	response to stress
F3P66_05645	COG1546	Belongs to the CinA family
F3P66_05645	COG1058	Belongs to the CinA family
F3P66_05650	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3P66_05695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3P66_05705	COG0525	valine-tRNA ligase activity
F3P66_05720	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
F3P66_05730	COG0316	Belongs to the HesB IscA family
F3P66_05735	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F3P66_05740	COG0018	arginyl-trna synthetase
F3P66_05750	COG1472	Belongs to the glycosyl hydrolase 3 family
F3P66_05755	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F3P66_05760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F3P66_05765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3P66_05770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3P66_05775	COG0805	protein transport
F3P66_05780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3P66_05785	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F3P66_05790	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3P66_05795	COG0739	heme binding
F3P66_05800	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3P66_05805	COG0746	molybdenum cofactor guanylyltransferase activity
F3P66_05810	COG2814	Major facilitator Superfamily
F3P66_05815	COG0697	spore germination
F3P66_05820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3P66_05830	COG0475	glutathione-regulated potassium exporter activity
F3P66_05830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3P66_05840	COG3706	GGDEF domain
F3P66_05845	COG0303	'Molybdopterin
F3P66_05850	COG0315	cyclic pyranopterin monophosphate synthase activity
F3P66_05855	COG0134	indole-3-glycerol-phosphate synthase activity
F3P66_05860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3P66_05885	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F3P66_05900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F3P66_05905	COG0343	queuine tRNA-ribosyltransferase activity
F3P66_05945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F3P66_05950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
F3P66_05975	COG0544	peptidyl-prolyl cis-trans isomerase activity
F3P66_06005	COG1368	sulfuric ester hydrolase activity
F3P66_06015	COG0823	Involved in the tonB-independent uptake of proteins
F3P66_06020	COG0778	Nitroreductase
F3P66_06030	COG0281	malic enzyme
F3P66_06030	COG0280	phosphate acetyltransferase
F3P66_06045	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_06050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3P66_06055	COG1127	ABC transporter
F3P66_06130	COG3264	Mechanosensitive ion channel
F3P66_06130	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F3P66_06140	COG0745	RESPONSE REGULATOR receiver
F3P66_06145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3P66_06150	COG0640	Transcriptional regulator
F3P66_06160	COG0740	serine-type endopeptidase activity
F3P66_06170	COG2226	methyltransferase
F3P66_06175	COG1309	transcriptional regulator
F3P66_06185	COG0187	DNA topoisomerase II activity
F3P66_06195	COG0149	triose-phosphate isomerase activity
F3P66_06205	COG0504	CTP synthase activity
F3P66_06215	COG0114	fumarate hydratase activity
F3P66_06225	COG0546	phosphoglycolate phosphatase activity
F3P66_06230	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F3P66_06245	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F3P66_06260	COG2003	Belongs to the UPF0758 family
F3P66_06265	COG0024	Methionine aminopeptidase
F3P66_06270	COG1489	DNA binding
F3P66_06275	COG3243	poly(R)-hydroxyalkanoic acid synthase
F3P66_06290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3P66_06295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3P66_06300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3P66_06310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3P66_06355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3P66_06380	COG1126	abc transporter atp-binding protein
F3P66_06385	COG0765	amino acid transport
F3P66_06390	COG4597	amino acid ABC transporter
F3P66_06395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_06400	COG0626	cystathionine gamma-synthase activity
F3P66_06415	COG0596	Alpha beta hydrolase
F3P66_06430	COG2124	cytochrome p450
F3P66_06460	COG1862	Preprotein translocase
F3P66_06490	COG1064	alcohol dehydrogenase
F3P66_06495	COG0321	lipoyl(octanoyl) transferase activity
F3P66_06525	COG0242	peptide deformylase activity
F3P66_06535	COG0243	molybdopterin cofactor binding
F3P66_06540	COG2239	Acts as a magnesium transporter
F3P66_06570	COG0668	transmembrane transport
F3P66_06640	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3P66_06650	COG0667	Aldo Keto reductase
F3P66_06670	COG1121	(ABC) transporter
F3P66_06675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3P66_06690	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3P66_06695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3P66_06710	COG0629	single-stranded DNA binding
F3P66_06715	COG3609	addiction module antidote protein, CC2985 family
F3P66_06725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
F3P66_06725	COG0617	tRNA 3'-terminal CCA addition
F3P66_06725	COG0517	IMP dehydrogenase activity
F3P66_06730	COG2095	MarC family integral membrane protein
F3P66_06735	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3P66_06795	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3P66_06805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3P66_06810	COG0084	hydrolase, TatD family'
F3P66_06815	COG0321	lipoyl(octanoyl) transferase activity
F3P66_06815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3P66_06835	COG0798	PFAM Bile acid sodium symporter
F3P66_06845	COG0431	NADPH-dependent FMN reductase
F3P66_06850	COG2826	transposase and inactivated derivatives, IS30 family
F3P66_06895	COG0450	alkyl hydroperoxide reductase
F3P66_06905	COG1671	Belongs to the UPF0178 family
F3P66_06915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3P66_06920	COG0251	oxidation-reduction process
F3P66_06940	COG0564	pseudouridine synthase activity
F3P66_06945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F3P66_06970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3P66_06975	COG0509	glycine decarboxylation via glycine cleavage system
F3P66_06980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3P66_06980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3P66_07005	COG0275	rRNA processing
F3P66_07020	COG1648	precorrin-2 dehydrogenase activity
F3P66_07020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3P66_07030	COG3956	TIGRFAM MazG family protein
F3P66_07035	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3P66_07040	COG1923	regulation of RNA biosynthetic process
F3P66_07045	COG0569	domain protein
F3P66_07050	COG2204	response regulator
F3P66_07055	COG5000	phosphorelay sensor kinase activity
F3P66_07060	COG2204	response regulator
F3P66_07065	COG3852	Histidine kinase
F3P66_07075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F3P66_07075	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F3P66_07085	COG2867	negative regulation of translational initiation
F3P66_07110	COG0697	spore germination
F3P66_07115	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F3P66_07125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3P66_07135	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3P66_07145	COG0022	dehydrogenase e1 component
F3P66_07145	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3P66_07150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3P66_07165	COG0148	phosphopyruvate hydratase activity
F3P66_07170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F3P66_07190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3P66_07205	COG1024	Enoyl-CoA hydratase
F3P66_07220	COG1960	acyl-CoA dehydrogenase activity
F3P66_07225	COG0683	leucine binding
F3P66_07245	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F3P66_07250	COG1063	alcohol dehydrogenase
F3P66_07255	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_07260	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_07270	COG2182	Extracellular solute-binding protein
F3P66_07280	COG0395	ABC-type sugar transport system, permease component
F3P66_07290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3P66_07295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_07300	COG0765	amino acid transport
F3P66_07305	COG0765	amino acid transport
F3P66_07310	COG4598	ABC transporter
F3P66_07315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3P66_07330	COG0372	Belongs to the citrate synthase family
F3P66_07340	COG0765	amino acid transport
F3P66_07345	COG0765	amino acid transport
F3P66_07355	COG2186	Transcriptional regulator
F3P66_07360	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3P66_07365	COG3494	Protein of unknown function (DUF1009)
F3P66_07370	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3P66_07375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3P66_07380	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3P66_07385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3P66_07390	COG0750	zinc metalloprotease
F3P66_07400	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3P66_07405	COG0233	cytoplasmic translational termination
F3P66_07410	COG0528	UMP kinase activity
F3P66_07415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F3P66_07420	COG0052	Belongs to the universal ribosomal protein uS2 family
F3P66_07450	COG0537	adenosine 5'-monophosphoramidase activity
F3P66_07480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3P66_07510	COG3106	COG3106 Predicted ATPase
F3P66_07515	COG3768	UPF0283 membrane protein
F3P66_07525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3P66_07530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3P66_07535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3P66_07545	COG0633	Ferredoxin
F3P66_07565	COG0384	phenazine biosynthesis protein PhzF
F3P66_07570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F3P66_07590	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3P66_07605	COG1530	ribonuclease E activity
F3P66_07610	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_07630	COG0436	Aminotransferase
F3P66_07640	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F3P66_07645	COG0511	ligase activity, forming carbon-carbon bonds
F3P66_07650	COG0439	Biotin carboxylase
F3P66_07655	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F3P66_07670	COG0456	acetyltransferase
F3P66_07680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3P66_07695	COG3811	Belongs to the UPF0386 family
F3P66_07700	COG0456	acetyltransferase
F3P66_07705	COG0154	amidase activity
F3P66_07710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3P66_07715	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F3P66_07720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F3P66_07745	COG0456	acetyltransferase
F3P66_07750	COG1960	acyl-CoA dehydrogenase activity
F3P66_07760	COG0540	Belongs to the ATCase OTCase family
F3P66_07770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F3P66_07775	COG0758	DNA mediated transformation
F3P66_07785	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3P66_07790	COG0557	exoribonuclease II activity
F3P66_07805	COG0477	Major facilitator Superfamily
F3P66_07810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F3P66_07825	COG0784	Response regulator, receiver
F3P66_07835	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3P66_07855	COG1136	(ABC) transporter
F3P66_07865	COG0442	prolyl-tRNA aminoacylation
F3P66_07890	COG1007	ATP synthesis coupled electron transport
F3P66_07905	COG0713	ATP synthesis coupled electron transport
F3P66_07915	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3P66_07920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F3P66_07930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F3P66_07935	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F3P66_07945	COG0649	NAD binding
F3P66_07955	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3P66_07960	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3P66_07965	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3P66_08000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3P66_08010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F3P66_08015	COG0740	serine-type endopeptidase activity
F3P66_08020	COG2199	diguanylate cyclase activity
F3P66_08025	COG2124	cytochrome p450
F3P66_08030	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_08055	COG1832	CoA-binding protein
F3P66_08070	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F3P66_08075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F3P66_08080	COG0010	Belongs to the arginase family
F3P66_08085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F3P66_08095	COG1612	heme a metabolic process
F3P66_08120	COG0297	glycogen (starch) synthase activity
F3P66_08175	COG3932	Exopolysaccharide synthesis, ExoD
F3P66_08205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3P66_08230	COG2897	thiosulfate sulfurtransferase activity
F3P66_08260	COG0737	Belongs to the 5'-nucleotidase family
F3P66_08265	COG0583	DNA-binding transcription factor activity
F3P66_08270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3P66_08285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3P66_08310	COG0444	Belongs to the ABC transporter superfamily
F3P66_08315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_08320	COG0601	transmembrane transport
F3P66_08425	COG0776	regulation of translation
F3P66_08430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3P66_08435	COG0416	fatty acid biosynthetic process
F3P66_08455	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F3P66_08460	COG2814	Major facilitator Superfamily
F3P66_08465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3P66_08470	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3P66_08475	COG1280	lysine exporter protein (LysE YggA)
F3P66_08485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3P66_08485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3P66_08490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F3P66_08495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F3P66_08515	COG0113	porphobilinogen synthase activity
F3P66_08525	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F3P66_08530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3P66_08540	COG0659	secondary active sulfate transmembrane transporter activity
F3P66_08545	COG4452	Inner membrane protein CreD
F3P66_08555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F3P66_08560	COG0477	Major facilitator Superfamily
F3P66_08565	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F3P66_08575	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3P66_08600	COG0248	Ppx GppA phosphatase
F3P66_08605	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F3P66_08615	COG0628	permease
F3P66_08620	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F3P66_08625	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3P66_08650	COG0243	molybdopterin cofactor binding
F3P66_08655	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3P66_08670	COG0625	glutathione transferase activity
F3P66_08680	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_08685	COG0322	excinuclease ABC activity
F3P66_08690	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3P66_08695	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F3P66_08700	COG0314	molybdopterin synthase activity
F3P66_08720	COG0105	UTP biosynthetic process
F3P66_08730	COG3706	GGDEF domain
F3P66_08735	COG0488	(ABC) transporter
F3P66_08750	COG4191	Histidine kinase
F3P66_08755	COG5001	Diguanylate cyclase
F3P66_08755	COG3300	MHYT domain
F3P66_08775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3P66_08790	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3P66_08800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F3P66_08805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3P66_08810	COG0400	carboxylic ester hydrolase activity
F3P66_08815	COG0194	GDP metabolic process
F3P66_08820	COG1561	YicC-like family, N-terminal region
F3P66_08825	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3P66_08835	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3P66_08840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3P66_08850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3P66_08855	COG0667	Aldo Keto reductase
F3P66_08865	COG0360	Binds together with S18 to 16S ribosomal RNA
F3P66_08870	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F3P66_08880	COG0359	binds to the 23S rRNA
F3P66_08905	COG0305	Participates in initiation and elongation during chromosome replication
F3P66_08915	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3P66_08945	COG1286	toxin biosynthetic process
F3P66_08950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3P66_08955	COG4221	oxidoreductase activity
F3P66_08960	COG0215	cysteine-tRNA ligase activity
F3P66_08970	COG2852	Protein conserved in bacteria
F3P66_09005	COG1652	LysM domain
F3P66_09010	COG5265	(ABC) transporter
F3P66_09015	COG0688	phosphatidylethanolamine metabolic process
F3P66_09020	COG1183	phosphatidylcholine synthase activity
F3P66_09040	COG1742	UPF0060 membrane protein
F3P66_09045	COG1051	belongs to the nudix hydrolase family
F3P66_09070	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F3P66_09080	COG0668	transmembrane transport
F3P66_09085	COG3443	Belongs to the bacterial solute-binding protein 9 family
F3P66_09090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_09105	COG0346	lactoylglutathione lyase activity
F3P66_09115	COG1418	mRNA catabolic process
F3P66_09130	COG2226	methyltransferase
F3P66_09140	COG1381	Involved in DNA repair and RecF pathway recombination
F3P66_09145	COG0784	Response regulator, receiver
F3P66_09155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3P66_09160	COG0571	ribonuclease III activity
F3P66_09165	COG0681	Belongs to the peptidase S26 family
F3P66_09170	COG0736	holo-[acyl-carrier-protein] synthase activity
F3P66_09190	COG1758	RNA polymerase activity
F3P66_09200	COG0840	transmembrane signaling receptor activity
F3P66_09210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F3P66_09215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_09225	COG0741	lytic transglycosylase activity
F3P66_09275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3P66_09300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3P66_09330	COG2814	Major facilitator Superfamily
F3P66_09340	COG1968	undecaprenyl-diphosphatase activity
F3P66_09345	COG1733	regulation of RNA biosynthetic process
F3P66_09350	COG0604	alcohol dehydrogenase
F3P66_09390	COG0443	Heat shock 70 kDa protein
F3P66_09410	COG0697	spore germination
F3P66_09415	COG0308	aminopeptidase N
F3P66_09425	COG2202	Pas domain
F3P66_09425	COG2205	protein histidine kinase activity
F3P66_09430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F3P66_09435	COG3713	MltA-interacting MipA family protein
F3P66_09440	COG2205	protein histidine kinase activity
F3P66_09450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3P66_09455	COG3088	subunit of a heme lyase
F3P66_09460	COG1138	Cytochrome C-type biogenesis protein
F3P66_09465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F3P66_09470	COG4235	cytochrome complex assembly
F3P66_09585	COG4695	Portal protein
F3P66_09635	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F3P66_09640	COG1621	beta-fructofuranosidase activity
F3P66_09650	COG2814	Major facilitator Superfamily
F3P66_09660	COG2337	Toxic component of a toxin-antitoxin (TA) module
F3P66_09690	COG3077	Addiction module antitoxin, RelB DinJ family
F3P66_09695	COG3041	Addiction module toxin RelE StbE family
F3P66_09705	COG2983	Belongs to the UPF0260 family
F3P66_09710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3P66_09780	COG2205	protein histidine kinase activity
F3P66_09790	COG2166	iron-sulfur cluster assembly
F3P66_09805	COG4957	zinc ion binding
F3P66_09810	COG1320	monovalent cation:proton antiporter activity
F3P66_09815	COG2212	antiporter activity
F3P66_09820	COG1863	multisubunit Na H antiporter MnhE subunit
F3P66_09825	COG0651	ATP synthesis coupled electron transport
F3P66_09830	COG1006	Multisubunit Na H antiporter MnhC subunit
F3P66_09835	COG2111	Na H antiporter
F3P66_09840	COG2111	Na H antiporter
F3P66_09840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3P66_09845	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3P66_09855	COG1272	protein, Hemolysin III
F3P66_09875	COG2514	catechol 2,3-dioxygenase activity
F3P66_09885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3P66_09885	COG2169	Transcriptional regulator
F3P66_09895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_09925	COG4176	ABC-type proline glycine betaine transport system permease component
F3P66_09930	COG0517	IMP dehydrogenase activity
F3P66_09930	COG4175	Glycine betaine
F3P66_09955	COG0789	Transcriptional regulator
F3P66_09985	COG2010	Cytochrome c
F3P66_09990	COG3909	cytochrome
F3P66_10000	COG2378	regulation of single-species biofilm formation
F3P66_10010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3P66_10025	COG0583	DNA-binding transcription factor activity
F3P66_10030	COG0840	transmembrane signaling receptor activity
F3P66_10035	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3P66_10040	COG4106	trans-aconitate 2-methyltransferase activity
F3P66_10050	COG2378	regulation of single-species biofilm formation
F3P66_10055	COG0656	L-ascorbic acid biosynthetic process
F3P66_10070	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
F3P66_10075	COG1733	regulation of RNA biosynthetic process
F3P66_10090	COG0433	COG0433 Predicted ATPase
F3P66_10105	COG4221	oxidoreductase activity
F3P66_10140	COG0488	(ABC) transporter
F3P66_10155	COG1764	response to oxidative stress
F3P66_10160	COG1846	Transcriptional regulator
F3P66_10165	COG1376	ErfK ybiS ycfS ynhG family protein
F3P66_10170	COG1376	ErfK ybiS ycfS ynhG family protein
F3P66_10190	COG1793	dna ligase
F3P66_10190	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
F3P66_10200	COG0477	Major facilitator Superfamily
F3P66_10250	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F3P66_10260	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_10265	COG1309	transcriptional regulator
F3P66_10275	COG2203	Gaf domain
F3P66_10275	COG2200	EAL domain
F3P66_10275	COG2199	diguanylate cyclase activity
F3P66_10295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3P66_10300	COG4208	sulfate ABC transporter
F3P66_10305	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3P66_10310	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3P66_10315	COG1959	2 iron, 2 sulfur cluster binding
F3P66_10320	COG0175	sulfate reduction
F3P66_10325	COG0175	sulfate reduction
F3P66_10330	COG2895	sulfate adenylyltransferase (ATP) activity
F3P66_10355	COG0579	oxidoreductase
F3P66_10390	COG1823	symporter activity
F3P66_10410	COG2514	catechol 2,3-dioxygenase activity
F3P66_10420	COG1196	nuclear chromosome segregation
F3P66_10425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3P66_10435	COG1194	a g-specific adenine glycosylase
F3P66_10455	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F3P66_10480	COG1802	Transcriptional regulator
F3P66_10485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3P66_10505	COG0612	Peptidase, M16
F3P66_10510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3P66_10530	COG1678	Uncharacterized ACR, COG1678
F3P66_10540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3P66_10540	COG0678	peroxiredoxin activity
F3P66_10555	COG0328	RNA-DNA hybrid ribonuclease activity
F3P66_10560	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3P66_10565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F3P66_10570	COG3346	SURF1 family
F3P66_10585	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F3P66_10595	COG0109	protoheme IX farnesyltransferase activity
F3P66_10600	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3P66_10625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3P66_10640	COG0259	pyridoxamine-phosphate oxidase activity
F3P66_10655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3P66_10670	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F3P66_10675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3P66_10675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3P66_10680	COG3214	Protein conserved in bacteria
F3P66_10685	COG1122	ATPase activity
F3P66_10690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3P66_10695	COG1268	BioY protein
F3P66_10700	COG0123	including yeast histone deacetylase and acetoin utilization protein
F3P66_10705	COG1722	exodeoxyribonuclease VII activity
F3P66_10710	COG1741	Belongs to the pirin family
F3P66_10715	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F3P66_10760	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
F3P66_10765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3P66_10785	COG1960	acyl-CoA dehydrogenase activity
F3P66_10810	COG4638	Rieske (2fe-2S)
F3P66_10820	COG0009	L-threonylcarbamoyladenylate synthase
F3P66_10855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3P66_10860	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3P66_10870	COG0356	it plays a direct role in the translocation of protons across the membrane
F3P66_10885	COG3158	transport of potassium into the cell
F3P66_10890	COG0598	Magnesium transport protein CorA
F3P66_10900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_10905	COG2197	response regulator
F3P66_10915	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_10920	COG3734	2-keto-3-deoxy-galactonokinase
F3P66_10925	COG0800	Aldolase
F3P66_10930	COG3386	PFAM SMP-30 Gluconolaconase
F3P66_10935	COG3300	MHYT domain
F3P66_10935	COG5001	Diguanylate cyclase
F3P66_10945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F3P66_10955	COG1663	tetraacyldisaccharide 4'-kinase activity
F3P66_10975	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_10980	COG0312	modulator of DNA gyrase
F3P66_10990	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3P66_10995	COG0742	ribosomal rna small subunit methyltransferase
F3P66_11000	COG1187	pseudouridine synthase activity
F3P66_11005	COG0590	tRNA wobble adenosine to inosine editing
F3P66_11015	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F3P66_11020	COG0196	riboflavin kinase activity
F3P66_11030	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F3P66_11035	COG0459	protein refolding
F3P66_11050	COG2259	Doxx family
F3P66_11055	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F3P66_11060	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
F3P66_11070	COG0124	histidyl-tRNA synthetase
F3P66_11090	COG0583	DNA-binding transcription factor activity
F3P66_11095	COG2855	membrane
F3P66_11105	COG0519	Catalyzes the synthesis of GMP from XMP
F3P66_11110	COG1376	ErfK ybiS ycfS ynhG family protein
F3P66_11120	COG0247	lactate metabolic process
F3P66_11125	COG0277	FAD linked oxidase domain protein
F3P66_11135	COG0277	FAD linked oxidase domain protein
F3P66_11140	COG0583	DNA-binding transcription factor activity
F3P66_11155	COG2186	Transcriptional regulator
F3P66_11165	COG0561	phosphatase activity
F3P66_11175	COG0306	phosphate transporter
F3P66_11195	COG0583	DNA-binding transcription factor activity
F3P66_11210	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F3P66_11220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3P66_11225	COG2183	response to ionizing radiation
F3P66_11230	COG0151	Belongs to the GarS family
F3P66_11240	COG0840	transmembrane signaling receptor activity
F3P66_11245	COG1683	Conserved Protein
F3P66_11255	COG0751	glycine-tRNA ligase activity
F3P66_11265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F3P66_11270	COG1704	LemA family
F3P66_11280	COG0752	glycyl-tRNA synthetase alpha subunit
F3P66_11305	COG0142	geranyltranstransferase activity
F3P66_11315	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F3P66_11320	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3P66_11370	COG0477	Major facilitator Superfamily
F3P66_11375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F3P66_11380	COG0248	Ppx GppA phosphatase
F3P66_11390	COG2205	protein histidine kinase activity
F3P66_11405	COG1177	transmembrane transport
F3P66_11410	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3P66_11415	COG3842	ATPase activity
F3P66_11430	COG2224	Isocitrate lyase
F3P66_11450	COG2081	HI0933 family
F3P66_11460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_11465	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3P66_11470	COG0363	glucosamine-6-phosphate deaminase activity
F3P66_11475	COG0129	dihydroxy-acid dehydratase activity
F3P66_11490	COG3842	ATPase activity
F3P66_11500	COG0395	ABC-type sugar transport system, permease component
F3P66_11505	COG1175	transmembrane transport
F3P66_11510	COG1653	transport
F3P66_11515	COG1609	Transcriptional regulator
F3P66_11520	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F3P66_11560	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3P66_11570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F3P66_11575	COG5443	negative regulation of bacterial-type flagellum assembly
F3P66_11595	COG1749	Flagellar hook protein flgE
F3P66_11620	COG1360	Flagellar Motor Protein
F3P66_11645	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3P66_11650	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3P66_11655	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3P66_11660	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3P66_11665	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3P66_11675	COG4786	Flagellar basal body rod
F3P66_11680	COG1157	protein secretion by the type III secretion system
F3P66_11690	COG1815	bacterial-type flagellum-dependent cell motility
F3P66_11695	COG1558	bacterial-type flagellum-dependent cell motility
F3P66_11700	COG1677	Flagellar hook-basal body complex protein FliE
F3P66_11705	COG4786	Flagellar basal body rod
F3P66_11710	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
F3P66_11715	COG1706	bacterial-type flagellum-dependent cell motility
F3P66_11725	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F3P66_11735	COG1338	Plays a role in the flagellum-specific transport system
F3P66_11755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3P66_11770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3P66_11785	COG5328	Belongs to the UPF0262 family
F3P66_11795	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F3P66_11800	COG0424	maF-like protein
F3P66_11805	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F3P66_11820	COG0436	Aminotransferase
F3P66_11825	COG1970	mechanosensitive ion channel activity
F3P66_11830	COG2205	protein histidine kinase activity
F3P66_11830	COG2198	Histidine kinase
F3P66_11830	COG0784	Response regulator, receiver
F3P66_11835	COG2972	Histidine kinase
F3P66_11835	COG0840	transmembrane signaling receptor activity
F3P66_11845	COG2771	luxR family
F3P66_11850	COG1766	The M ring may be actively involved in energy transduction
F3P66_11860	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
F3P66_11865	COG0745	RESPONSE REGULATOR receiver
F3P66_11870	COG2201	protein-glutamate methylesterase activity
F3P66_11875	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3P66_11880	COG0643	Histidine kinase
F3P66_11880	COG2198	Histidine kinase
F3P66_11885	COG0745	RESPONSE REGULATOR receiver
F3P66_11895	COG0840	transmembrane signaling receptor activity
F3P66_11905	COG2111	Na H antiporter
F3P66_11905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3P66_11910	COG1006	Multisubunit Na H antiporter MnhC subunit
F3P66_11915	COG0651	ATP synthesis coupled electron transport
F3P66_11920	COG1863	multisubunit Na H antiporter MnhE subunit
F3P66_11925	COG2212	antiporter activity
F3P66_11930	COG1320	monovalent cation:proton antiporter activity
F3P66_11955	COG1024	Enoyl-CoA hydratase
F3P66_11955	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3P66_11960	COG0183	Belongs to the thiolase family
F3P66_11965	COG1960	acyl-CoA dehydrogenase activity
F3P66_11980	COG0730	response to heat
F3P66_12000	COG1201	RNA secondary structure unwinding
F3P66_12005	COG1959	2 iron, 2 sulfur cluster binding
F3P66_12025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3P66_12040	COG0167	dihydroorotate dehydrogenase activity
F3P66_12090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3P66_12110	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F3P66_12345	COG0717	Belongs to the dCTP deaminase family
F3P66_12355	COG2967	ApaG domain
F3P66_12365	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3P66_12370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3P66_12385	COG0745	RESPONSE REGULATOR receiver
F3P66_12390	COG0704	Plays a role in the regulation of phosphate uptake
F3P66_12395	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3P66_12405	COG0573	inorganic phosphate transmembrane transporter activity
F3P66_12410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3P66_12415	COG5002	protein histidine kinase activity
F3P66_12420	COG2326	polyphosphate kinase activity
F3P66_12460	COG4774	siderophore transport
F3P66_12465	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3P66_12470	COG1840	ABC-type Fe3 transport system, periplasmic component
F3P66_12475	COG3842	ATPase activity
F3P66_12480	COG0318	PFAM AMP-dependent synthetase and ligase
F3P66_12485	COG0166	Belongs to the GPI family
F3P66_12505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3P66_12510	COG0418	dihydroorotase activity
F3P66_12515	COG3938	Belongs to the proline racemase family
F3P66_12525	COG0427	acetyl-CoA hydrolase
F3P66_12540	COG0395	ABC-type sugar transport system, permease component
F3P66_12545	COG1175	transmembrane transport
F3P66_12550	COG3842	ATPase activity
F3P66_12555	COG2226	methyltransferase
F3P66_12570	COG3850	Histidine kinase
F3P66_12570	COG5002	protein histidine kinase activity
F3P66_12575	COG0840	transmembrane signaling receptor activity
F3P66_12585	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F3P66_12590	COG0594	ribonuclease P activity
F3P66_12595	COG0706	membrane insertase activity
F3P66_12600	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F3P66_12615	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F3P66_12640	COG0071	Belongs to the small heat shock protein (HSP20) family
F3P66_12650	COG0840	transmembrane signaling receptor activity
F3P66_12660	COG2171	N-acyltransferase activity
F3P66_12665	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3P66_12675	COG0101	tRNA pseudouridine synthase activity
F3P66_12680	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3P66_12685	COG0242	peptide deformylase activity
F3P66_12695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_12700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F3P66_12705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F3P66_12710	COG1396	sequence-specific DNA binding
F3P66_12715	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F3P66_12725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F3P66_12730	COG1702	phosphate starvation-inducible protein PhoH
F3P66_12735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3P66_12760	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F3P66_12770	COG0180	Tryptophanyl-tRNA synthetase
F3P66_12785	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F3P66_12790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F3P66_12805	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F3P66_12810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3P66_12825	COG0776	regulation of translation
F3P66_12830	COG0616	signal peptide processing
F3P66_12840	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3P66_12845	COG1137	ATPase activity
F3P66_12855	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3P66_12860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3P66_12865	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F3P66_12870	COG1420	regulation of RNA biosynthetic process
F3P66_12875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F3P66_12880	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F3P66_12885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3P66_12890	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3P66_12895	COG0268	Binds directly to 16S ribosomal RNA
F3P66_12900	COG1024	Enoyl-CoA hydratase
F3P66_12905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F3P66_12910	COG2226	methyltransferase
F3P66_12915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F3P66_12930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3P66_12935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F3P66_12940	COG0756	dUTP diphosphatase activity
F3P66_12945	COG1280	lysine exporter protein (LysE YggA)
F3P66_12950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3P66_12955	COG0606	chelatase, subunit chli
F3P66_12960	COG0189	ligase activity
F3P66_12970	COG3842	ATPase activity
F3P66_12975	COG0395	ABC-type sugar transport system, permease component
F3P66_12980	COG1175	transmembrane transport
F3P66_12995	COG0792	nuclease activity
F3P66_13000	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3P66_13010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3P66_13020	COG0284	orotidine-5'-phosphate decarboxylase activity
F3P66_13040	COG1968	undecaprenyl-diphosphatase activity
F3P66_13050	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3P66_13060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3P66_13090	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
F3P66_13105	COG0519	Catalyzes the synthesis of GMP from XMP
F3P66_13105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3P66_13115	COG1309	transcriptional regulator
F3P66_13130	COG1393	Belongs to the ArsC family
F3P66_13135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3P66_13140	COG2309	aminopeptidase activity
F3P66_13145	COG0697	spore germination
F3P66_13150	COG1846	Transcriptional regulator
F3P66_13160	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_13165	COG1570	exodeoxyribonuclease VII activity
F3P66_13190	COG4977	sequence-specific DNA binding
F3P66_13195	COG0667	Aldo Keto reductase
F3P66_13210	COG0667	Aldo Keto reductase
F3P66_13215	COG0072	phenylalanine-tRNA ligase activity
F3P66_13215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3P66_13220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F3P66_13230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F3P66_13235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F3P66_13240	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F3P66_13265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3P66_13270	COG2169	Transcriptional regulator
F3P66_13270	COG1917	Cupin 2, conserved barrel domain protein
F3P66_13285	COG1396	sequence-specific DNA binding
F3P66_13300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3P66_13305	COG0481	GTPase activity
F3P66_13335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P66_13340	COG0697	spore germination
F3P66_13345	COG3757	hydrolase, family 25
F3P66_13350	COG3422	double-strand break repair
F3P66_13405	COG4964	Belongs to the GSP D family
F3P66_13440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3P66_13445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F3P66_13455	COG0791	NLP P60 protein
F3P66_13470	COG0697	spore germination
F3P66_13490	COG4269	membrane
F3P66_13500	COG1840	ABC-type Fe3 transport system, periplasmic component
F3P66_13505	COG1959	2 iron, 2 sulfur cluster binding
F3P66_13515	COG1732	Glycine betaine
F3P66_13520	COG1174	glycine betaine transport
F3P66_13525	COG1125	glycine betaine transport
F3P66_13530	COG1174	glycine betaine transport
F3P66_13535	COG3265	gluconokinase activity
F3P66_13540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_13545	COG0174	glutamine synthetase
F3P66_13555	COG4172	Belongs to the ABC transporter superfamily
F3P66_13560	COG4239	(ABC) transporter, permease
F3P66_13565	COG4174	ABC transporter (Permease)
F3P66_13570	COG4166	transmembrane transport
F3P66_13580	COG1803	Methylglyoxal synthase
F3P66_13585	COG0837	glucose binding
F3P66_13590	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F3P66_13595	COG2188	Transcriptional regulator
F3P66_13600	COG3624	Phosphonate C-P lyase system protein PhnG
F3P66_13605	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F3P66_13610	COG3626	phosphonate metabolism
F3P66_13615	COG3627	carbon phosphorus lyase activity
F3P66_13620	COG4107	phosphonate C-P lyase system protein PhnK
F3P66_13625	COG4778	phosphonate C-P lyase system protein PhnL
F3P66_13635	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3P66_13640	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F3P66_13645	COG3639	organic phosphonate transmembrane transporter activity
F3P66_13650	COG3639	organic phosphonate transmembrane transporter activity
F3P66_13655	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3P66_13660	COG3454	Phosphonate metabolism
F3P66_13665	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3P66_13685	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3P66_13695	COG0848	biopolymer transport protein
F3P66_13715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_13750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3P66_13760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3P66_13775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F3P66_13780	COG0070	glutamate synthase
F3P66_13780	COG0067	glutamate synthase
F3P66_13780	COG0069	glutamate synthase activity
F3P66_13790	COG0477	Major facilitator Superfamily
F3P66_13800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3P66_13805	COG1845	cytochrome c oxidase, subunit III
F3P66_13810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3P66_13820	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3P66_13825	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F3P66_13830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F3P66_13840	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F3P66_13845	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F3P66_13850	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3P66_13855	COG0295	cytidine deaminase activity
F3P66_13860	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3P66_13870	COG3845	ABC transporter
F3P66_13875	COG1744	ABC transporter substrate-binding protein PnrA-like
F3P66_13880	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3P66_13895	COG0443	Heat shock 70 kDa protein
F3P66_13900	COG0484	heat shock protein binding
F3P66_13910	COG2900	Belongs to the SlyX family
F3P66_13945	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F3P66_13955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3P66_13955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3P66_13970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3P66_13980	COG1278	Cold shock
F3P66_13990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3P66_13995	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3P66_14010	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F3P66_14015	COG0077	Prephenate dehydratase
F3P66_14015	COG1605	Chorismate mutase
F3P66_14020	COG2816	NAD+ diphosphatase activity
F3P66_14035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3P66_14040	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F3P66_14050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F3P66_14055	COG2951	lytic endotransglycosylase activity
F3P66_14060	COG2814	Major facilitator Superfamily
F3P66_14065	COG0779	Required for maturation of 30S ribosomal subunits
F3P66_14080	COG3064	Membrane
F3P66_14080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F3P66_14085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F3P66_14090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F3P66_14095	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F3P66_14100	COG1185	polyribonucleotide nucleotidyltransferase activity
F3P66_14105	COG2813	Specifically methylates the guanine in position
F3P66_14115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_14145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F3P66_14165	COG1780	Probably involved in ribonucleotide reductase function
F3P66_14175	COG1072	(Pantothenic acid kinase))
F3P66_14255	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F3P66_14270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3P66_14280	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F3P66_14285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F3P66_14290	COG0131	Imidazoleglycerol-phosphate dehydratase
F3P66_14300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3P66_14305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F3P66_14310	COG0107	imidazoleglycerol-phosphate synthase activity
F3P66_14315	COG0140	phosphoribosyl-ATP diphosphatase activity
F3P66_14320	COG1072	(Pantothenic acid kinase))
F3P66_14330	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F3P66_14335	COG0745	RESPONSE REGULATOR receiver
F3P66_14340	COG0642	Histidine kinase
F3P66_14345	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
F3P66_14350	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3P66_14350	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3P66_14355	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3P66_14360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3P66_14370	COG2205	protein histidine kinase activity
F3P66_14380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3P66_14405	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F3P66_14410	COG0159	tryptophan synthase activity
F3P66_14415	COG0133	tryptophan synthase activity
F3P66_14420	COG0135	phosphoribosylanthranilate isomerase activity
F3P66_14435	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3P66_14460	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F3P66_14470	COG3030	protein affecting phage T7 exclusion by the F plasmid
F3P66_14475	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F3P66_14485	COG0237	dephospho-CoA kinase activity
F3P66_14490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3P66_14495	COG0424	maF-like protein
F3P66_14500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F3P66_14510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F3P66_14515	COG1981	membrane
F3P66_14520	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3P66_14525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F3P66_14530	COG0445	tRNA wobble uridine modification
F3P66_14535	COG0357	Ribosomal RNA small subunit methyltransferase G
F3P66_14555	COG0501	Belongs to the peptidase M48B family
F3P66_14560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3P66_14560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3P66_14630	COG3842	ATPase activity
F3P66_14635	COG3842	ATPase activity
F3P66_14680	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_14715	COG0601	transmembrane transport
F3P66_14720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_14740	COG0747	negative chemotaxis
F3P66_14770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_14775	COG0601	transmembrane transport
F3P66_14830	COG4178	(ABC) transporter
F3P66_14840	COG1609	Transcriptional regulator
F3P66_14855	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_14860	COG1735	metal-dependent hydrolase with the TIM-barrel fold
F3P66_14895	COG1794	racemase activity, acting on amino acids and derivatives
F3P66_14900	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_14905	COG1309	transcriptional regulator
F3P66_14910	COG2233	PERMEase
F3P66_14950	COG1595	DNA-templated transcription, initiation
F3P66_14960	COG0395	ABC-type sugar transport system, permease component
F3P66_14965	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3P66_14975	COG3842	ATPase activity
F3P66_15010	COG1653	transport
F3P66_15020	COG0395	ABC-type sugar transport system, permease component
F3P66_15025	COG3842	ATPase activity
F3P66_15030	COG0395	ABC-type sugar transport system, permease component
F3P66_15035	COG1175	transmembrane transport
F3P66_15065	COG1609	Transcriptional regulator
F3P66_15075	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3P66_15080	COG1082	Xylose isomerase domain protein TIM barrel
F3P66_15085	COG3842	ATPase activity
F3P66_15090	COG0395	ABC-type sugar transport system, permease component
F3P66_15095	COG1175	transmembrane transport
F3P66_15100	COG1653	transport
F3P66_15105	COG1309	transcriptional regulator
F3P66_15110	COG0673	inositol 2-dehydrogenase activity
F3P66_15125	COG0673	inositol 2-dehydrogenase activity
F3P66_15135	COG1278	Cold shock
F3P66_15145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3P66_15165	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F3P66_15180	COG3842	ATPase activity
F3P66_15185	COG0395	ABC-type sugar transport system, permease component
F3P66_15190	COG1175	transmembrane transport
F3P66_15210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3P66_15215	COG3618	amidohydrolase
F3P66_15220	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_15225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_15230	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_15235	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
F3P66_15245	COG2186	Transcriptional regulator
F3P66_15300	COG2223	nitrite transmembrane transporter activity
F3P66_15305	COG0583	DNA-binding transcription factor activity
F3P66_15310	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3P66_15320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3P66_15325	COG2084	Dehydrogenase
F3P66_15340	COG1609	Transcriptional regulator
F3P66_15345	COG1063	alcohol dehydrogenase
F3P66_15350	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_15365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_15370	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
F3P66_15375	COG1175	transmembrane transport
F3P66_15380	COG0395	ABC-type sugar transport system, permease component
F3P66_15395	COG0395	ABC-type sugar transport system, permease component
F3P66_15400	COG1175	transmembrane transport
F3P66_15405	COG2182	Extracellular solute-binding protein
F3P66_15410	COG0626	cystathionine gamma-synthase activity
F3P66_15425	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3P66_15435	COG1121	(ABC) transporter
F3P66_15440	COG0523	cobalamin synthesis protein
F3P66_15455	COG0523	cobalamin synthesis protein
F3P66_15460	COG1653	transport
F3P66_15465	COG1175	transmembrane transport
F3P66_15470	COG0395	ABC-type sugar transport system, permease component
F3P66_15475	COG3842	ATPase activity
F3P66_15490	COG3047	cAMP biosynthetic process
F3P66_15515	COG0583	DNA-binding transcription factor activity
F3P66_15520	COG1879	ABC-type sugar transport system periplasmic component
F3P66_15525	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_15530	COG1129	ABC transporter
F3P66_15540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3P66_15545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_15550	COG5002	protein histidine kinase activity
F3P66_15550	COG3447	MASE1 domain protein
F3P66_15550	COG5001	Diguanylate cyclase
F3P66_15555	COG3257	ureidoglycine aminohydrolase activity
F3P66_15565	COG5001	Diguanylate cyclase
F3P66_15580	COG0747	negative chemotaxis
F3P66_15585	COG0601	transmembrane transport
F3P66_15590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_15600	COG4608	Belongs to the ABC transporter superfamily
F3P66_15605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F3P66_15620	COG0129	dihydroxy-acid dehydratase activity
F3P66_15630	COG1879	ABC-type sugar transport system periplasmic component
F3P66_15635	COG1129	ABC transporter
F3P66_15640	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_15645	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_15650	COG2186	Transcriptional regulator
F3P66_15660	COG0587	DNA-directed DNA polymerase activity
F3P66_15700	COG3842	ATPase activity
F3P66_15705	COG0395	ABC-type sugar transport system, permease component
F3P66_15710	COG1175	transmembrane transport
F3P66_15715	COG1653	transport
F3P66_15725	COG0673	inositol 2-dehydrogenase activity
F3P66_15740	COG5001	Diguanylate cyclase
F3P66_15745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_15755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F3P66_15760	COG2894	cell division
F3P66_15765	COG0850	regulation of cytokinetic process
F3P66_15775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3P66_15780	COG2186	Transcriptional regulator
F3P66_15785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3P66_15795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3P66_15805	COG1312	Catalyzes the dehydration of D-mannonate
F3P66_15820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3P66_15825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3P66_15830	COG4172	Belongs to the ABC transporter superfamily
F3P66_15835	COG1921	L-seryl-tRNASec selenium transferase activity
F3P66_15850	COG3964	amidohydrolase
F3P66_15860	COG0601	transmembrane transport
F3P66_15870	COG0747	negative chemotaxis
F3P66_15880	COG0438	transferase activity, transferring glycosyl groups
F3P66_15915	COG4989	oxidoreductase activity
F3P66_15930	COG3842	ATPase activity
F3P66_15935	COG1653	transport
F3P66_15940	COG1175	transmembrane transport
F3P66_15945	COG0395	ABC-type sugar transport system, permease component
F3P66_15950	COG1501	Belongs to the glycosyl hydrolase 31 family
F3P66_15955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_15960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_15965	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
F3P66_15970	COG0352	thiamine-phosphate diphosphorylase activity
F3P66_15975	COG0351	phosphomethylpyrimidine kinase
F3P66_15980	COG1522	sequence-specific DNA binding
F3P66_15985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3P66_15990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_16005	COG2204	response regulator
F3P66_16010	COG4191	Histidine kinase
F3P66_16015	COG1301	dicarboxylic acid transport
F3P66_16025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3P66_16030	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_16040	COG1473	amidohydrolase
F3P66_16060	COG1215	transferase activity, transferring glycosyl groups
F3P66_16070	COG2942	2-epimerase
F3P66_16140	COG3307	-O-antigen
F3P66_16145	COG1596	polysaccharide export
F3P66_16150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3P66_16165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3P66_16170	COG0840	transmembrane signaling receptor activity
F3P66_16175	COG1376	ErfK ybiS ycfS ynhG family protein
F3P66_16175	COG1388	LysM domain
F3P66_16185	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_16195	COG2094	Belongs to the DNA glycosylase MPG family
F3P66_16215	COG1653	transport
F3P66_16230	COG3842	ATPase activity
F3P66_16240	COG0673	inositol 2-dehydrogenase activity
F3P66_16245	COG0602	queuosine metabolic process
F3P66_16250	COG0720	synthase
F3P66_16255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F3P66_16260	COG0673	inositol 2-dehydrogenase activity
F3P66_16275	COG0395	ABC-type sugar transport system, permease component
F3P66_16280	COG1175	transmembrane transport
F3P66_16300	COG0583	DNA-binding transcription factor activity
F3P66_16305	COG0280	phosphate acetyltransferase
F3P66_16305	COG0281	malic enzyme
F3P66_16320	COG0765	amino acid transport
F3P66_16325	COG1126	abc transporter atp-binding protein
F3P66_16335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3P66_16370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3P66_16375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3P66_16380	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3P66_16385	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_16390	COG1129	ABC transporter
F3P66_16425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_16430	COG0601	transmembrane transport
F3P66_16435	COG0583	DNA-binding transcription factor activity
F3P66_16440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_16445	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3P66_16465	COG1595	DNA-templated transcription, initiation
F3P66_16470	COG1120	ATPase activity
F3P66_16475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P66_16490	COG2226	methyltransferase
F3P66_16500	COG1120	ATPase activity
F3P66_16505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P66_16525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3P66_16535	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_16540	COG0473	3-isopropylmalate dehydrogenase activity
F3P66_16545	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_16550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_16580	COG0601	transmembrane transport
F3P66_16585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_16590	COG4172	Belongs to the ABC transporter superfamily
F3P66_16595	COG1522	sequence-specific DNA binding
F3P66_16600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_16610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_16615	COG1126	abc transporter atp-binding protein
F3P66_16625	COG1473	amidohydrolase
F3P66_16630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16640	COG1959	2 iron, 2 sulfur cluster binding
F3P66_16655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16680	COG1960	acyl-CoA dehydrogenase activity
F3P66_16715	COG0667	Aldo Keto reductase
F3P66_16725	COG0583	DNA-binding transcription factor activity
F3P66_16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16750	COG1473	amidohydrolase
F3P66_16755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_16795	COG4608	Belongs to the ABC transporter superfamily
F3P66_16800	COG0444	Belongs to the ABC transporter superfamily
F3P66_16810	COG0601	transmembrane transport
F3P66_16820	COG2186	Transcriptional regulator
F3P66_16845	COG3453	Protein conserved in bacteria
F3P66_16845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P66_16850	COG0640	Transcriptional regulator
F3P66_16860	COG2391	methyltransferase activity
F3P66_16865	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F3P66_16880	COG0022	dehydrogenase e1 component
F3P66_16890	COG1960	acyl-CoA dehydrogenase activity
F3P66_16895	COG0183	Belongs to the thiolase family
F3P66_16905	COG1960	acyl-CoA dehydrogenase activity
F3P66_16910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3P66_16925	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F3P66_16930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F3P66_16935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F3P66_16940	COG4952	isomerase
F3P66_16945	COG3347	Dehydrogenase
F3P66_16945	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_16950	COG1349	DNA-binding transcription factor activity
F3P66_16965	COG1129	ABC transporter
F3P66_16970	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_16980	COG3254	rhamnose metabolic process
F3P66_16995	COG2264	protein methyltransferase activity
F3P66_17000	COG5001	Diguanylate cyclase
F3P66_17025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3P66_17030	COG4208	sulfate ABC transporter
F3P66_17040	COG4150	thiosulfate binding
F3P66_17060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3P66_17070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3P66_17080	COG1040	competence protein
F3P66_17085	COG2226	methyltransferase
F3P66_17100	COG0494	nUDIX hydrolase
F3P66_17110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F3P66_17115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3P66_17120	COG0653	protein targeting
F3P66_17125	COG0697	spore germination
F3P66_17165	COG1312	Catalyzes the dehydration of D-mannonate
F3P66_17170	COG0246	Mannitol dehydrogenase
F3P66_17190	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_17195	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_17200	COG1129	ABC transporter
F3P66_17235	COG2376	Dihydroxyacetone kinase
F3P66_17240	COG3273	potassium ion transport
F3P66_17240	COG0471	metal ion transport
F3P66_17260	COG0438	transferase activity, transferring glycosyl groups
F3P66_17270	COG2244	polysaccharide biosynthetic process
F3P66_17295	COG0489	protein tyrosine kinase activity
F3P66_17295	COG3206	protein involved in exopolysaccharide biosynthesis
F3P66_17320	COG0438	transferase activity, transferring glycosyl groups
F3P66_17335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3P66_17340	COG2273	Hydrolase Family 16
F3P66_17340	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F3P66_17385	COG1396	sequence-specific DNA binding
F3P66_17395	COG1129	ABC transporter
F3P66_17400	COG4214	carbohydrate transport
F3P66_17405	COG4213	ABC transporter substrate-binding protein
F3P66_17420	COG0346	lactoylglutathione lyase activity
F3P66_17425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3P66_17425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F3P66_17430	COG4770	biotin carboxylase activity
F3P66_17440	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F3P66_17450	COG0625	glutathione transferase activity
F3P66_17455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3P66_17460	COG3800	Transcriptional regulator
F3P66_17460	COG1396	sequence-specific DNA binding
F3P66_17470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3P66_17480	COG0300	oxidoreductase activity
F3P66_17490	COG2096	Adenosyltransferase
F3P66_17500	COG2086	electron transfer activity
F3P66_17510	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3P66_17515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3P66_17520	COG0165	Argininosuccinate lyase
F3P66_17560	COG2884	Cell division ATP-binding protein ftsE
F3P66_17580	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3P66_17590	COG0287	Prephenate dehydrogenase
F3P66_17595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3P66_17600	COG2226	methyltransferase
F3P66_17605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P66_17620	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F3P66_17625	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F3P66_17660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F3P66_17665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F3P66_17680	COG4974	Belongs to the 'phage' integrase family
F3P66_17685	COG0825	malonyl-CoA metabolic process
F3P66_17690	COG3034	peptidoglycan biosynthetic process
F3P66_17695	COG0425	Belongs to the sulfur carrier protein TusA family
F3P66_17695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F3P66_17705	COG0523	cobalamin synthesis protein
F3P66_17710	COG1686	Belongs to the peptidase S11 family
F3P66_17715	COG1473	amidohydrolase
F3P66_17725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3P66_17835	COG0456	acetyltransferase
F3P66_17865	COG2267	carboxylic ester hydrolase activity
F3P66_17880	COG1959	2 iron, 2 sulfur cluster binding
F3P66_17885	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F3P66_17930	COG2226	methyltransferase
F3P66_17965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3P66_17985	COG1629	transport
F3P66_17985	COG4774	siderophore transport
F3P66_17990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F3P66_17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P66_18000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P66_18005	COG1120	ATPase activity
F3P66_18020	COG4953	penicillin-binding protein 1C
F3P66_18025	COG2373	Large extracellular alpha-helical protein
F3P66_18030	COG2835	tetraacyldisaccharide 4'-kinase activity
F3P66_18040	COG3118	belongs to the thioredoxin family
F3P66_18055	COG0625	glutathione transferase activity
F3P66_18065	COG0482	sulfurtransferase activity
F3P66_18080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3P66_18095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3P66_18100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3P66_18105	COG0037	tRNA processing
F3P66_18115	COG2885	chlorophyll binding
F3P66_18120	COG0823	Involved in the tonB-independent uptake of proteins
F3P66_18140	COG0824	Thioesterase
F3P66_18150	COG0494	nUDIX hydrolase
F3P66_18165	COG2255	four-way junction helicase activity
F3P66_18170	COG0632	four-way junction helicase activity
F3P66_18175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F3P66_18180	COG0840	transmembrane signaling receptor activity
F3P66_18185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_18190	COG0217	transcriptional regulatory protein
F3P66_18205	COG1692	metallophosphoesterase
F3P66_18215	COG1253	flavin adenine dinucleotide binding
F3P66_18250	COG3263	regulation of cellular component size
F3P66_18255	COG0126	phosphoglycerate kinase activity
F3P66_18260	COG3588	fructose-bisphosphate aldolase
F3P66_18280	COG0254	rRNA binding
F3P66_18285	COG1132	(ABC) transporter
F3P66_18305	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_18335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3P66_18340	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3P66_18345	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F3P66_18355	COG3750	Belongs to the UPF0335 family
F3P66_18375	COG0469	pyruvate kinase activity
F3P66_18380	COG3108	Peptidase M15
F3P66_18385	COG2204	response regulator
F3P66_18390	COG1164	Oligoendopeptidase f
F3P66_18395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3P66_18405	COG5310	Homospermidine synthase
F3P66_18415	COG0737	Belongs to the 5'-nucleotidase family
F3P66_18420	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F3P66_18425	COG0330	HflC and HflK could
F3P66_18455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3P66_18460	COG2951	lytic endotransglycosylase activity
F3P66_18475	COG2205	protein histidine kinase activity
F3P66_18485	COG0070	glutamate synthase
F3P66_18485	COG0069	glutamate synthase activity
F3P66_18485	COG0067	glutamate synthase
F3P66_18495	COG0745	RESPONSE REGULATOR receiver
F3P66_18500	COG2205	protein histidine kinase activity
F3P66_18505	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F3P66_18510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F3P66_18515	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F3P66_18530	COG0252	asparaginase activity
F3P66_18540	COG1027	Aspartate ammonia-lyase
F3P66_18545	COG2186	Transcriptional regulator
F3P66_18580	COG4176	ABC-type proline glycine betaine transport system permease component
F3P66_18585	COG0517	IMP dehydrogenase activity
F3P66_18585	COG4175	Glycine betaine
F3P66_18590	COG2986	histidine ammonia-lyase
F3P66_18595	COG2814	Major facilitator Superfamily
F3P66_18610	COG1522	sequence-specific DNA binding
F3P66_18615	COG0583	DNA-binding transcription factor activity
F3P66_18620	COG0667	Aldo Keto reductase
F3P66_18630	COG1335	isochorismatase
F3P66_18640	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_18645	COG3254	rhamnose metabolic process
F3P66_18660	COG2721	sulfolactate sulfo-lyase activity
F3P66_18665	COG1129	ABC transporter
F3P66_18675	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_18680	COG1879	ABC-type sugar transport system periplasmic component
F3P66_18890	COG2308	Evidence 4 Homologs of previously reported genes of
F3P66_18890	COG2307	Protein conserved in bacteria
F3P66_18905	COG0488	(ABC) transporter
F3P66_18910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3P66_18915	COG1304	FMN binding
F3P66_18935	COG1070	Carbohydrate kinase
F3P66_18945	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3P66_18950	COG0667	Aldo Keto reductase
F3P66_18960	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_18965	COG1129	ABC transporter
F3P66_18970	COG1879	ABC-type sugar transport system periplasmic component
F3P66_19020	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3P66_19035	COG0395	ABC-type sugar transport system, permease component
F3P66_19050	COG3842	ATPase activity
F3P66_19070	COG0243	molybdopterin cofactor binding
F3P66_19085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3P66_19090	COG1116	anion transmembrane transporter activity
F3P66_19095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_19100	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_19110	COG3707	response regulator
F3P66_19115	COG1802	Transcriptional regulator
F3P66_19120	COG1914	H( )-stimulated, divalent metal cation uptake system
F3P66_19125	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3P66_19130	COG4336	lyase activity
F3P66_19135	COG1984	allophanate hydrolase subunit 2
F3P66_19140	COG4770	biotin carboxylase activity
F3P66_19145	COG0366	Alpha amylase catalytic
F3P66_19155	COG4771	TonB-dependent receptor
F3P66_19185	COG1414	Transcriptional regulator
F3P66_19190	COG1475	DNA binding
F3P66_19195	COG1192	Involved in chromosome partitioning
F3P66_19230	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F3P66_19240	COG2986	histidine ammonia-lyase
F3P66_19245	COG1228	amidohydrolase
F3P66_19250	COG0402	S-adenosylhomocysteine deaminase activity
F3P66_19310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_19320	COG2423	ornithine cyclodeaminase activity
F3P66_19335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_19345	COG4176	ABC-type proline glycine betaine transport system permease component
F3P66_19355	COG4175	Glycine betaine
F3P66_19355	COG3448	diguanylate cyclase activity
F3P66_19365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_19370	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_19375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_19405	COG0673	inositol 2-dehydrogenase activity
F3P66_19410	COG0673	inositol 2-dehydrogenase activity
F3P66_19420	COG1175	transmembrane transport
F3P66_19425	COG0395	ABC-type sugar transport system, permease component
F3P66_19430	COG3842	ATPase activity
F3P66_19440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P66_19445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3P66_19470	COG0583	DNA-binding transcription factor activity
F3P66_19475	COG0346	lactoylglutathione lyase activity
F3P66_19490	COG1574	metal-dependent hydrolase with the TIM-barrel fold
F3P66_19500	COG2814	Major facilitator Superfamily
F3P66_19515	COG0583	DNA-binding transcription factor activity
F3P66_19520	COG0477	Major facilitator Superfamily
F3P66_19570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F3P66_19580	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F3P66_19585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3P66_19590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3P66_19620	COG0010	Belongs to the arginase family
F3P66_19640	COG0697	spore germination
F3P66_19645	COG0673	inositol 2-dehydrogenase activity
F3P66_19670	COG0477	Major facilitator Superfamily
F3P66_19675	COG0642	Histidine kinase
F3P66_19685	COG2194	sulfuric ester hydrolase activity
F3P66_19695	COG0583	DNA-binding transcription factor activity
F3P66_19700	COG4774	siderophore transport
F3P66_19715	COG1120	ATPase activity
F3P66_19725	COG3474	cytochrome
F3P66_19730	COG2137	regulation of response to DNA damage stimulus
F3P66_19735	COG3386	PFAM SMP-30 Gluconolaconase
F3P66_19745	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_19750	COG1129	ABC transporter
F3P66_19755	COG1879	ABC-type sugar transport system periplasmic component
F3P66_19765	COG4585	Histidine kinase
F3P66_19770	COG2197	response regulator
F3P66_19780	COG2133	pyrroloquinoline quinone binding
F3P66_19790	COG0500	methyltransferase
F3P66_19795	COG0564	pseudouridine synthase activity
F3P66_19810	COG4175	Glycine betaine
F3P66_19810	COG0517	IMP dehydrogenase activity
F3P66_19815	COG4176	ABC-type proline glycine betaine transport system permease component
F3P66_19825	COG4191	Histidine kinase
F3P66_19825	COG0784	Response regulator, receiver
F3P66_19830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3P66_19835	COG3206	protein involved in exopolysaccharide biosynthesis
F3P66_19835	COG0489	protein tyrosine kinase activity
F3P66_19840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3P66_19845	COG1215	transferase activity, transferring glycosyl groups
F3P66_19850	COG1215	transferase activity, transferring glycosyl groups
F3P66_19860	COG2273	Hydrolase Family 16
F3P66_19865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3P66_19870	COG2244	polysaccharide biosynthetic process
F3P66_19875	COG0463	Glycosyl transferase, family 2
F3P66_19880	COG2327	Polysaccharide pyruvyl transferase
F3P66_19885	COG1215	transferase activity, transferring glycosyl groups
F3P66_19905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3P66_19915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_19930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3P66_19930	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P66_19955	COG0033	Phosphoglucomutase
F3P66_19960	COG0297	glycogen (starch) synthase activity
F3P66_19965	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F3P66_19970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F3P66_19975	COG0058	SHG alpha-glucan phosphorylase activity
F3P66_19990	COG1794	racemase activity, acting on amino acids and derivatives
F3P66_19995	COG1522	sequence-specific DNA binding
F3P66_20005	COG2084	Dehydrogenase
F3P66_20010	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_20015	COG1063	alcohol dehydrogenase
F3P66_20025	COG4988	ABC transporter
F3P66_20030	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3P66_20040	COG1294	oxidase, subunit
F3P66_20070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3P66_20075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F3P66_20105	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F3P66_20110	COG0539	negative regulation of cytoplasmic translation
F3P66_20140	COG4221	oxidoreductase activity
F3P66_20150	COG0006	proline dipeptidase activity
F3P66_20155	COG0747	negative chemotaxis
F3P66_20160	COG0601	transmembrane transport
F3P66_20165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_20170	COG0444	Belongs to the ABC transporter superfamily
F3P66_20175	COG4608	Belongs to the ABC transporter superfamily
F3P66_20190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_20215	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3P66_20235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3P66_20240	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_20260	COG4993	Dehydrogenase
F3P66_20265	COG3685	Protein conserved in bacteria
F3P66_20295	COG0693	protein deglycase activity
F3P66_20320	COG0189	ligase activity
F3P66_20325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P66_20330	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3P66_20340	COG0583	DNA-binding transcription factor activity
F3P66_20345	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_20350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_20355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_20360	COG1116	anion transmembrane transporter activity
F3P66_20375	COG1522	sequence-specific DNA binding
F3P66_20390	COG0784	Response regulator, receiver
F3P66_20400	COG3920	Histidine kinase
F3P66_20410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3P66_20425	COG0019	diaminopimelate decarboxylase activity
F3P66_20435	COG0513	Belongs to the DEAD box helicase family
F3P66_20445	COG0527	aspartate kinase activity
F3P66_20455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F3P66_20460	COG2890	protein-(glutamine-N5) methyltransferase activity
F3P66_20475	COG0542	response to heat
F3P66_20480	COG0739	heme binding
F3P66_20480	COG0741	lytic transglycosylase activity
F3P66_20480	COG1196	nuclear chromosome segregation
F3P66_20525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_20535	COG2186	Transcriptional regulator
F3P66_20540	COG0747	negative chemotaxis
F3P66_20545	COG0601	transmembrane transport
F3P66_20550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_20555	COG4172	Belongs to the ABC transporter superfamily
F3P66_20595	COG1881	PFAM PEBP family protein
F3P66_20635	COG3833	ABC-type maltose transport systems, permease component
F3P66_20655	COG1278	Cold shock
F3P66_20660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3P66_20665	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3P66_20685	COG0300	oxidoreductase activity
F3P66_20695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3P66_20695	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P66_20700	COG4311	Sarcosine oxidase, delta subunit
F3P66_20705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_20710	COG4977	sequence-specific DNA binding
F3P66_20720	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3P66_20725	COG2218	PFAM glutamate synthase alpha subunit domain protein
F3P66_20730	COG0069	glutamate synthase activity
F3P66_20735	COG0174	glutamine synthetase
F3P66_20755	COG0765	amino acid transport
F3P66_20760	COG1126	abc transporter atp-binding protein
F3P66_20765	COG1454	alcohol dehydrogenase
F3P66_20775	COG2267	carboxylic ester hydrolase activity
F3P66_20785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_20790	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_20810	COG1177	transmembrane transport
F3P66_20815	COG3842	ATPase activity
F3P66_20830	COG3842	ATPase activity
F3P66_20835	COG0395	ABC-type sugar transport system, permease component
F3P66_20840	COG1175	transmembrane transport
F3P66_20850	COG3976	FMN-binding domain protein
F3P66_20850	COG1053	succinate dehydrogenase
F3P66_20865	COG4172	Belongs to the ABC transporter superfamily
F3P66_20875	COG0601	transmembrane transport
F3P66_20885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_20900	COG2828	Protein conserved in bacteria
F3P66_20905	COG0583	DNA-binding transcription factor activity
F3P66_20915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P66_20935	COG0494	nUDIX hydrolase
F3P66_20940	COG0583	DNA-binding transcription factor activity
F3P66_20950	COG0511	ligase activity, forming carbon-carbon bonds
F3P66_20955	COG0439	Biotin carboxylase
F3P66_20970	COG1984	allophanate hydrolase subunit 2
F3P66_20975	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3P66_20980	COG0436	Aminotransferase
F3P66_20990	COG4221	oxidoreductase activity
F3P66_20995	COG0765	amino acid transport
F3P66_21000	COG0765	amino acid transport
F3P66_21005	COG1126	abc transporter atp-binding protein
F3P66_21010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_21015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3P66_21030	COG0583	DNA-binding transcription factor activity
F3P66_21040	COG0583	DNA-binding transcription factor activity
F3P66_21045	COG2814	Major facilitator Superfamily
F3P66_21060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3P66_21070	COG2207	Transcriptional regulator
F3P66_21075	COG0668	transmembrane transport
F3P66_21085	COG4566	intracellular signal transduction
F3P66_21105	COG0668	transmembrane transport
F3P66_21110	COG4191	Histidine kinase
F3P66_21115	COG0784	Response regulator, receiver
F3P66_21115	COG2205	protein histidine kinase activity
F3P66_21115	COG5002	protein histidine kinase activity
F3P66_21120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P66_21135	COG0047	phosphoribosylformylglycinamidine synthase activity
F3P66_21150	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P66_21150	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3P66_21160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F3P66_21175	COG1309	transcriptional regulator
F3P66_21180	COG1063	alcohol dehydrogenase
F3P66_21190	COG1879	ABC-type sugar transport system periplasmic component
F3P66_21200	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_21350	COG5001	Diguanylate cyclase
F3P66_21360	COG1253	flavin adenine dinucleotide binding
F3P66_21375	COG3842	ATPase activity
F3P66_21380	COG0395	ABC-type sugar transport system, permease component
F3P66_21385	COG1175	transmembrane transport
F3P66_21390	COG1653	transport
F3P66_21400	COG0673	inositol 2-dehydrogenase activity
F3P66_21405	COG1609	Transcriptional regulator
F3P66_21415	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_21420	COG0583	DNA-binding transcription factor activity
F3P66_21430	COG1879	ABC-type sugar transport system periplasmic component
F3P66_21435	COG1129	ABC transporter
F3P66_21440	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_21445	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_21450	COG1609	Transcriptional regulator
F3P66_21460	COG0673	inositol 2-dehydrogenase activity
F3P66_21520	COG0714	Associated with various cellular activities
F3P66_21525	COG3256	nitric oxide reductase
F3P66_21540	COG1845	cytochrome c oxidase, subunit III
F3P66_21555	COG0163	prenyltransferase activity
F3P66_21560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F3P66_21565	COG3189	MarR family transcriptional regulator
F3P66_21575	COG0826	peptidase U32
F3P66_21630	COG0243	molybdopterin cofactor binding
F3P66_21640	COG3005	denitrification pathway
F3P66_21645	COG0583	DNA-binding transcription factor activity
F3P66_21655	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3P66_21660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_21675	COG1960	acyl-CoA dehydrogenase activity
F3P66_21680	COG0583	DNA-binding transcription factor activity
F3P66_21685	COG1609	Transcriptional regulator
F3P66_21695	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3P66_21705	COG3842	ATPase activity
F3P66_21715	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3P66_21725	COG1473	amidohydrolase
F3P66_21740	COG0747	negative chemotaxis
F3P66_21745	COG0601	transmembrane transport
F3P66_21750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_21755	COG0444	Belongs to the ABC transporter superfamily
F3P66_21760	COG4608	Belongs to the ABC transporter superfamily
F3P66_21770	COG0583	DNA-binding transcription factor activity
F3P66_21775	COG0747	negative chemotaxis
F3P66_21785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_21790	COG0154	amidase activity
F3P66_21795	COG0693	protein deglycase activity
F3P66_21805	COG1473	amidohydrolase
F3P66_21810	COG4172	Belongs to the ABC transporter superfamily
F3P66_21815	COG2390	Transcriptional regulator
F3P66_21825	COG1175	transmembrane transport
F3P66_21830	COG0395	ABC-type sugar transport system, permease component
F3P66_21845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3P66_21850	COG1069	ribulokinase activity
F3P66_21855	COG1737	Transcriptional regulator
F3P66_21880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3P66_21900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3P66_21905	COG1414	Transcriptional regulator
F3P66_21910	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_21920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3P66_21925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3P66_21930	COG1121	(ABC) transporter
F3P66_21935	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3P66_21950	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3P66_21960	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3P66_21965	COG0471	metal ion transport
F3P66_21965	COG3273	potassium ion transport
F3P66_21970	COG1253	flavin adenine dinucleotide binding
F3P66_21975	COG1309	transcriptional regulator
F3P66_21995	COG1609	Transcriptional regulator
F3P66_22000	COG1070	Carbohydrate kinase
F3P66_22010	COG2115	Belongs to the xylose isomerase family
F3P66_22025	COG0778	Nitroreductase
F3P66_22030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3P66_22035	COG2011	ABC-type metal ion transport system permease component
F3P66_22045	COG5001	Diguanylate cyclase
F3P66_22045	COG3300	MHYT domain
F3P66_22050	COG1054	Belongs to the UPF0176 family
F3P66_22060	COG2954	triphosphatase activity
F3P66_22065	COG0800	Aldolase
F3P66_22090	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F3P66_22115	COG0523	cobalamin synthesis protein
F3P66_22125	COG1846	Transcriptional regulator
F3P66_22130	COG1609	Transcriptional regulator
F3P66_22140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3P66_22145	COG0673	inositol 2-dehydrogenase activity
F3P66_22155	COG3718	enzyme involved in inositol metabolism
F3P66_22165	COG3962	Belongs to the TPP enzyme family
F3P66_22170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_22185	COG0411	ABC transporter
F3P66_22200	COG0683	leucine binding
F3P66_22220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_22230	COG0747	negative chemotaxis
F3P66_22255	COG1082	Xylose isomerase domain protein TIM barrel
F3P66_22255	COG3185	4-Hydroxyphenylpyruvate dioxygenase
F3P66_22265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F3P66_22270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3P66_22275	COG1126	abc transporter atp-binding protein
F3P66_22280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_22285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_22290	COG0765	amino acid transport
F3P66_22295	COG0765	amino acid transport
F3P66_22305	COG3485	protocatechuate 3,4-dioxygenase
F3P66_22310	COG3485	protocatechuate 3,4-dioxygenase
F3P66_22315	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3P66_22325	COG0583	DNA-binding transcription factor activity
F3P66_22340	COG1414	Transcriptional regulator
F3P66_22350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3P66_22355	COG0183	Belongs to the thiolase family
F3P66_22360	COG1609	Transcriptional regulator
F3P66_22380	COG0673	inositol 2-dehydrogenase activity
F3P66_22390	COG1609	Transcriptional regulator
F3P66_22395	COG0395	ABC-type sugar transport system, permease component
F3P66_22400	COG1175	transmembrane transport
F3P66_22405	COG3842	ATPase activity
F3P66_22415	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
F3P66_22435	COG1940	carbohydrate kinase activity
F3P66_22445	COG3842	ATPase activity
F3P66_22450	COG4149	molybdate abc transporter
F3P66_22460	COG0584	glycerophosphoryl diester phosphodiesterase
F3P66_22465	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_22470	COG0300	oxidoreductase activity
F3P66_22490	COG3842	ATPase activity
F3P66_22510	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3P66_22545	COG0667	Aldo Keto reductase
F3P66_22550	COG0583	DNA-binding transcription factor activity
F3P66_22560	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3P66_22570	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_22580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P66_22595	COG1132	(ABC) transporter
F3P66_22635	COG1215	transferase activity, transferring glycosyl groups
F3P66_22650	COG1215	transferase activity, transferring glycosyl groups
F3P66_22660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F3P66_22665	COG1091	dTDP-4-dehydrorhamnose reductase activity
F3P66_22670	COG1088	dTDP-glucose 4,6-dehydratase activity
F3P66_22675	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F3P66_22690	COG0444	Belongs to the ABC transporter superfamily
F3P66_22695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_22700	COG0601	transmembrane transport
F3P66_22705	COG2186	Transcriptional regulator
F3P66_22710	COG1312	Catalyzes the dehydration of D-mannonate
F3P66_22715	COG0747	negative chemotaxis
F3P66_22725	COG5001	Diguanylate cyclase
F3P66_22725	COG3300	MHYT domain
F3P66_22730	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_22740	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
F3P66_22750	COG0306	phosphate transporter
F3P66_22755	COG1392	Phosphate transport regulator
F3P66_22780	COG5002	protein histidine kinase activity
F3P66_22795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F3P66_22810	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_22825	COG3119	arylsulfatase activity
F3P66_22830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P66_22835	COG3842	ATPase activity
F3P66_22840	COG0165	Argininosuccinate lyase
F3P66_22845	COG0395	ABC-type sugar transport system, permease component
F3P66_22850	COG1175	transmembrane transport
F3P66_22855	COG2182	Extracellular solute-binding protein
F3P66_22860	COG1940	carbohydrate kinase activity
F3P66_22885	COG1486	melibiose metabolic process
F3P66_22890	COG0747	negative chemotaxis
F3P66_22895	COG0601	transmembrane transport
F3P66_22900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_22905	COG4172	Belongs to the ABC transporter superfamily
F3P66_22910	COG1486	melibiose metabolic process
F3P66_22915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_22920	COG0842	Transport permease protein
F3P66_22920	COG1129	ABC transporter
F3P66_22940	COG0784	Response regulator, receiver
F3P66_22945	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3P66_22955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_22960	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3P66_22980	COG0765	amino acid transport
F3P66_22990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P66_23000	COG3938	Belongs to the proline racemase family
F3P66_23020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_23025	COG0765	amino acid transport
F3P66_23030	COG0765	amino acid transport
F3P66_23040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3P66_23055	COG0402	S-adenosylhomocysteine deaminase activity
F3P66_23065	COG0601	transmembrane transport
F3P66_23070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_23080	COG0402	S-adenosylhomocysteine deaminase activity
F3P66_23085	COG0444	Belongs to the ABC transporter superfamily
F3P66_23090	COG4608	Belongs to the ABC transporter superfamily
F3P66_23095	COG1802	Transcriptional regulator
F3P66_23100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P66_23125	COG3383	formate dehydrogenase (NAD+) activity
F3P66_23135	COG2223	nitrite transmembrane transporter activity
F3P66_23165	COG3237	CsbD-like
F3P66_23170	COG2197	response regulator
F3P66_23175	COG2186	Transcriptional regulator
F3P66_23180	COG0747	negative chemotaxis
F3P66_23185	COG0601	transmembrane transport
F3P66_23190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_23195	COG0405	Gamma-glutamyltransferase
F3P66_23205	COG3237	CsbD-like
F3P66_23215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3P66_23220	COG3181	Tripartite tricarboxylate transporter family receptor
F3P66_23225	COG5265	(ABC) transporter
F3P66_23230	COG0488	(ABC) transporter
F3P66_23255	COG1049	propionate catabolic process, 2-methylcitrate cycle
F3P66_23260	COG0840	transmembrane signaling receptor activity
F3P66_23270	COG0110	maltose O-acetyltransferase activity
F3P66_23280	COG1063	alcohol dehydrogenase
F3P66_23285	COG3284	Transcriptional regulator
F3P66_23305	COG1129	ABC transporter
F3P66_23310	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_23315	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_23330	COG1082	Xylose isomerase domain protein TIM barrel
F3P66_23340	COG1126	abc transporter atp-binding protein
F3P66_23345	COG0765	amino acid transport
F3P66_23350	COG0765	amino acid transport
F3P66_23355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_23360	COG3608	succinylglutamate desuccinylase aspartoacylase
F3P66_23365	COG0006	proline dipeptidase activity
F3P66_23370	COG2423	ornithine cyclodeaminase activity
F3P66_23375	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3P66_23380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P66_23385	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3P66_23390	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_23395	COG1522	sequence-specific DNA binding
F3P66_23405	COG3046	protein related to deoxyribodipyrimidine photolyase
F3P66_23450	COG4566	intracellular signal transduction
F3P66_23460	COG0243	molybdopterin cofactor binding
F3P66_23465	COG0783	Belongs to the Dps family
F3P66_23485	COG0784	Response regulator, receiver
F3P66_23485	COG4191	Histidine kinase
F3P66_23495	COG1840	ABC-type Fe3 transport system, periplasmic component
F3P66_23500	COG1840	ABC-type Fe3 transport system, periplasmic component
F3P66_23510	COG3842	ATPase activity
F3P66_23515	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_23530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P66_23555	COG2197	response regulator
F3P66_23560	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3P66_23565	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3P66_23575	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
F3P66_23580	COG4310	Domain of unknown function (DUF2172)
F3P66_23585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P66_23595	COG2197	response regulator
F3P66_23600	COG4566	intracellular signal transduction
F3P66_23630	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3P66_23650	COG0438	transferase activity, transferring glycosyl groups
F3P66_23665	COG1522	sequence-specific DNA binding
F3P66_23700	COG1414	Transcriptional regulator
F3P66_23710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3P66_23750	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F3P66_23785	COG1349	DNA-binding transcription factor activity
F3P66_23790	COG1879	ABC-type sugar transport system periplasmic component
F3P66_23795	COG1129	ABC transporter
F3P66_23800	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_23805	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_23825	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_23900	COG1846	Transcriptional regulator
F3P66_23920	COG0667	Aldo Keto reductase
F3P66_24030	COG1475	DNA binding
F3P66_24035	COG1192	Involved in chromosome partitioning
F3P66_24075	COG2207	Transcriptional regulator
F3P66_24095	COG1566	PFAM secretion protein HlyD family protein
F3P66_24105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3P66_24160	COG3920	Histidine kinase
F3P66_24170	COG0431	NADPH-dependent FMN reductase
F3P66_24190	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_24240	COG1278	Cold shock
F3P66_24260	COG4191	Histidine kinase
F3P66_24260	COG0784	Response regulator, receiver
F3P66_24300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3P66_24310	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3P66_24315	COG2080	2 iron, 2 sulfur cluster binding
F3P66_24320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3P66_24325	COG1309	transcriptional regulator
F3P66_24340	COG3685	Protein conserved in bacteria
F3P66_24355	COG0753	catalase activity
F3P66_24405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_24410	COG0765	amino acid transport
F3P66_24420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3P66_24425	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_24430	COG0006	proline dipeptidase activity
F3P66_24435	COG0504	CTP synthase activity
F3P66_24470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3P66_24490	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_24495	COG1414	Transcriptional regulator
F3P66_24500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3P66_24505	COG3842	ATPase activity
F3P66_24510	COG0395	ABC-type sugar transport system, permease component
F3P66_24515	COG1175	transmembrane transport
F3P66_24525	COG4948	Mandelate Racemase Muconate Lactonizing
F3P66_24530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_24535	COG3734	2-keto-3-deoxy-galactonokinase
F3P66_24570	COG0071	Belongs to the small heat shock protein (HSP20) family
F3P66_24575	COG3831	ATPase activity
F3P66_24585	COG0596	Alpha beta hydrolase
F3P66_24590	COG1902	pentaerythritol trinitrate reductase activity
F3P66_24595	COG4221	oxidoreductase activity
F3P66_24605	COG0840	transmembrane signaling receptor activity
F3P66_24630	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_24640	COG1082	Xylose isomerase domain protein TIM barrel
F3P66_24650	COG0673	inositol 2-dehydrogenase activity
F3P66_24655	COG1082	Xylose isomerase domain protein TIM barrel
F3P66_24660	COG1609	Transcriptional regulator
F3P66_24705	COG2072	flavoprotein involved in K transport
F3P66_24710	COG3842	ATPase activity
F3P66_24715	COG1177	transmembrane transport
F3P66_24730	COG0583	DNA-binding transcription factor activity
F3P66_24750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P66_24760	COG1177	transmembrane transport
F3P66_24775	COG3842	ATPase activity
F3P66_24780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_24785	COG0765	amino acid transport
F3P66_24795	COG2186	Transcriptional regulator
F3P66_24805	COG0583	DNA-binding transcription factor activity
F3P66_24815	COG1012	belongs to the aldehyde dehydrogenase family
F3P66_24840	COG0673	inositol 2-dehydrogenase activity
F3P66_24845	COG0667	Aldo Keto reductase
F3P66_24855	COG1376	ErfK ybiS ycfS ynhG family protein
F3P66_24865	COG0789	Transcriptional regulator
F3P66_24880	COG0673	inositol 2-dehydrogenase activity
F3P66_24885	COG2267	carboxylic ester hydrolase activity
F3P66_24900	COG0583	DNA-binding transcription factor activity
F3P66_24910	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_24915	COG0583	DNA-binding transcription factor activity
F3P66_24925	COG1063	alcohol dehydrogenase
F3P66_24930	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_24945	COG1136	(ABC) transporter
F3P66_24945	COG0577	efflux transmembrane transporter activity
F3P66_24950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P66_24960	COG0745	RESPONSE REGULATOR receiver
F3P66_24970	COG2084	Dehydrogenase
F3P66_24975	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F3P66_24980	COG2948	multi-organism process
F3P66_24985	COG3504	Conjugal transfer protein
F3P66_24990	COG3736	Type IV secretory pathway, component VirB8
F3P66_25000	COG3704	protein secretion by the type IV secretion system
F3P66_25015	COG3451	type IV secretory pathway VirB4
F3P66_25020	COG3702	type iv secretory pathway
F3P66_25025	COG3838	Conjugal transfer protein Trbc
F3P66_25080	COG1733	regulation of RNA biosynthetic process
F3P66_25100	COG1285	pathogenesis
F3P66_25140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P66_25145	COG1454	alcohol dehydrogenase
F3P66_25155	COG1414	Transcriptional regulator
F3P66_25165	COG0577	efflux transmembrane transporter activity
F3P66_25190	COG1177	transmembrane transport
F3P66_25200	COG3842	ATPase activity
F3P66_25220	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_25225	COG0745	RESPONSE REGULATOR receiver
F3P66_25235	COG0745	RESPONSE REGULATOR receiver
F3P66_25240	COG0156	8-amino-7-oxononanoate synthase activity
F3P66_25290	COG3505	Type IV secretory pathway VirD4
F3P66_25295	COG3831	ATPase activity
F3P66_25310	COG5489	Protein of unknown function (DUF736)
F3P66_25400	COG3920	Histidine kinase
F3P66_25455	COG1609	Transcriptional regulator
F3P66_25470	COG3395	kinase activity
F3P66_25480	COG1454	alcohol dehydrogenase
F3P66_25485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F3P66_25500	COG0747	negative chemotaxis
F3P66_25505	COG0601	transmembrane transport
F3P66_25510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_25520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P66_25535	COG1846	Transcriptional regulator
F3P66_25540	COG1737	Transcriptional regulator
F3P66_25545	COG3842	ATPase activity
F3P66_25555	COG0395	ABC-type sugar transport system, permease component
F3P66_25560	COG1175	transmembrane transport
F3P66_25595	COG0071	Belongs to the small heat shock protein (HSP20) family
F3P66_25670	COG3177	Filamentation induced by cAMP protein fic
F3P66_25740	COG0210	DNA helicase
F3P66_25745	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F3P66_25810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3P66_25835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P66_25840	COG1126	abc transporter atp-binding protein
F3P66_25855	COG0640	Transcriptional regulator
F3P66_25860	COG1475	DNA binding
F3P66_25865	COG1192	Involved in chromosome partitioning
F3P66_25925	COG1566	PFAM secretion protein HlyD family protein
F3P66_25980	COG5314	conjugation
F3P66_25990	COG3846	protein secretion by the type IV secretion system
F3P66_25995	COG3701	Conjugal transfer protein
F3P66_26045	COG0583	DNA-binding transcription factor activity
F3P66_26110	COG3436	PFAM IS66 Orf2 family protein
F3P66_26265	COG3161	chorismate lyase activity
F3P66_26355	COG0483	inositol monophosphate 1-phosphatase activity
F3P66_26360	COG0584	glycerophosphoryl diester phosphodiesterase
F3P66_26365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_26400	COG1283	sodium-dependent phosphate transmembrane transporter activity
F3P66_26485	COG5489	Protein of unknown function (DUF736)
F3P66_26490	COG0494	nUDIX hydrolase
F3P66_26515	COG5489	Protein of unknown function (DUF736)
F3P66_26535	COG2824	Alkylphosphonate utilization operon protein PhnA
F3P66_26560	COG1475	DNA binding
F3P66_26650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_26655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_26665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3P66_26675	COG0583	DNA-binding transcription factor activity
F3P66_26680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_26695	COG0601	transmembrane transport
F3P66_26700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P66_26705	COG4172	Belongs to the ABC transporter superfamily
F3P66_26730	COG1129	ABC transporter
F3P66_26735	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3P66_26765	COG1028	Short-chain dehydrogenase reductase Sdr
F3P66_26770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P66_26780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P66_26785	COG1116	anion transmembrane transporter activity
F3P66_26805	COG0583	DNA-binding transcription factor activity
F3P66_26855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3P66_26860	COG0640	Transcriptional regulator
F3P66_26865	COG1475	DNA binding
F3P66_26870	COG1192	Involved in chromosome partitioning
F3P66_26880	COG4962	Type ii secretion system protein e
F3P66_26900	COG5314	conjugation
F3P66_26910	COG3846	protein secretion by the type IV secretion system
F3P66_26915	COG3701	Conjugal transfer protein
F3P66_26965	COG0583	DNA-binding transcription factor activity
F3P66_27025	COG3436	PFAM IS66 Orf2 family protein