locus-tag	class	description
FY134_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY134_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY134_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY134_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY134_00025	COG1420	regulation of RNA biosynthetic process
FY134_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY134_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY134_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY134_00050	COG1137	ATPase activity
FY134_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY134_00065	COG0616	signal peptide processing
FY134_00070	COG0776	regulation of translation
FY134_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY134_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY134_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY134_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY134_00115	COG0728	peptidoglycan biosynthetic process
FY134_00125	COG0180	Tryptophanyl-tRNA synthetase
FY134_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY134_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY134_00145	COG0456	acetyltransferase
FY134_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY134_00165	COG1702	phosphate starvation-inducible protein PhoH
FY134_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY134_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY134_00185	COG1396	sequence-specific DNA binding
FY134_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY134_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY134_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_00210	COG0242	peptide deformylase activity
FY134_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY134_00220	COG0101	tRNA pseudouridine synthase activity
FY134_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY134_00235	COG2171	N-acyltransferase activity
FY134_00245	COG0840	transmembrane signaling receptor activity
FY134_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY134_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY134_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY134_00295	COG0706	membrane insertase activity
FY134_00300	COG0594	ribonuclease P activity
FY134_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY134_00310	COG0840	transmembrane signaling receptor activity
FY134_00325	COG2226	methyltransferase
FY134_00330	COG3842	ATPase activity
FY134_00335	COG1175	transmembrane transport
FY134_00340	COG0395	ABC-type sugar transport system, permease component
FY134_00355	COG0427	acetyl-CoA hydrolase
FY134_00365	COG3938	Belongs to the proline racemase family
FY134_00370	COG0418	dihydroorotase activity
FY134_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY134_00395	COG0166	Belongs to the GPI family
FY134_00400	COG0318	PFAM AMP-dependent synthetase and ligase
FY134_00405	COG3842	ATPase activity
FY134_00410	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_00415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY134_00420	COG4774	siderophore transport
FY134_00465	COG2326	polyphosphate kinase activity
FY134_00470	COG5002	protein histidine kinase activity
FY134_00475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY134_00480	COG0573	inorganic phosphate transmembrane transporter activity
FY134_00490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY134_00495	COG0704	Plays a role in the regulation of phosphate uptake
FY134_00500	COG0745	RESPONSE REGULATOR receiver
FY134_00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY134_00515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY134_00525	COG2967	ApaG domain
FY134_00540	COG0717	Belongs to the dCTP deaminase family
FY134_00550	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FY134_00570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY134_00620	COG0167	dihydroorotate dehydrogenase activity
FY134_00635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_00655	COG1959	2 iron, 2 sulfur cluster binding
FY134_00660	COG1201	RNA secondary structure unwinding
FY134_00680	COG0730	response to heat
FY134_00690	COG1960	acyl-CoA dehydrogenase activity
FY134_00695	COG0183	Belongs to the thiolase family
FY134_00700	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY134_00700	COG1024	Enoyl-CoA hydratase
FY134_00720	COG1320	monovalent cation:proton antiporter activity
FY134_00725	COG2212	antiporter activity
FY134_00730	COG1863	multisubunit Na H antiporter MnhE subunit
FY134_00735	COG0651	ATP synthesis coupled electron transport
FY134_00740	COG1006	Multisubunit Na H antiporter MnhC subunit
FY134_00745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY134_00745	COG2111	Na H antiporter
FY134_00755	COG0840	transmembrane signaling receptor activity
FY134_00765	COG0745	RESPONSE REGULATOR receiver
FY134_00770	COG0643	Histidine kinase
FY134_00770	COG2198	Histidine kinase
FY134_00775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY134_00780	COG2201	protein-glutamate methylesterase activity
FY134_00785	COG0745	RESPONSE REGULATOR receiver
FY134_00790	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY134_00800	COG1766	The M ring may be actively involved in energy transduction
FY134_00805	COG2771	luxR family
FY134_00815	COG2972	Histidine kinase
FY134_00815	COG0840	transmembrane signaling receptor activity
FY134_00820	COG2205	protein histidine kinase activity
FY134_00820	COG0784	Response regulator, receiver
FY134_00820	COG2198	Histidine kinase
FY134_00830	COG1970	mechanosensitive ion channel activity
FY134_00835	COG0436	Aminotransferase
FY134_00850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY134_00855	COG0424	maF-like protein
FY134_00860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY134_00870	COG5328	Belongs to the UPF0262 family
FY134_00875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY134_00885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY134_00920	COG1338	Plays a role in the flagellum-specific transport system
FY134_00930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY134_00940	COG1706	bacterial-type flagellum-dependent cell motility
FY134_00945	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY134_00950	COG4786	Flagellar basal body rod
FY134_00955	COG1677	Flagellar hook-basal body complex protein FliE
FY134_00960	COG1558	bacterial-type flagellum-dependent cell motility
FY134_00965	COG1815	bacterial-type flagellum-dependent cell motility
FY134_00970	COG1280	lysine exporter protein (LysE YggA)
FY134_00980	COG1157	protein secretion by the type III secretion system
FY134_00985	COG4786	Flagellar basal body rod
FY134_00995	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY134_01000	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY134_01005	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY134_01010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY134_01015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY134_01035	COG1360	Flagellar Motor Protein
FY134_01060	COG1749	Flagellar hook protein flgE
FY134_01080	COG5443	negative regulation of bacterial-type flagellum assembly
FY134_01085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY134_01095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY134_01135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY134_01140	COG1609	Transcriptional regulator
FY134_01145	COG1653	transport
FY134_01150	COG1175	transmembrane transport
FY134_01155	COG0395	ABC-type sugar transport system, permease component
FY134_01160	COG0366	Alpha amylase catalytic
FY134_01165	COG3842	ATPase activity
FY134_01175	COG3609	addiction module antidote protein, CC2985 family
FY134_01190	COG0129	dihydroxy-acid dehydratase activity
FY134_01195	COG0363	glucosamine-6-phosphate deaminase activity
FY134_01200	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY134_01205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_01215	COG2081	HI0933 family
FY134_01235	COG2224	Isocitrate lyase
FY134_01250	COG3842	ATPase activity
FY134_01255	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_01260	COG1177	transmembrane transport
FY134_01270	COG2205	protein histidine kinase activity
FY134_01280	COG0248	Ppx GppA phosphatase
FY134_01285	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY134_01290	COG0477	Major facilitator Superfamily
FY134_01335	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY134_01340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY134_01350	COG0142	geranyltranstransferase activity
FY134_01375	COG0752	glycyl-tRNA synthetase alpha subunit
FY134_01385	COG1704	LemA family
FY134_01390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY134_01400	COG0751	glycine-tRNA ligase activity
FY134_01405	COG1683	Conserved Protein
FY134_01410	COG0840	transmembrane signaling receptor activity
FY134_01420	COG0151	Belongs to the GarS family
FY134_01425	COG2183	response to ionizing radiation
FY134_01430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY134_01440	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY134_01455	COG0583	DNA-binding transcription factor activity
FY134_01475	COG0306	phosphate transporter
FY134_01485	COG0561	phosphatase activity
FY134_01490	COG0438	transferase activity, transferring glycosyl groups
FY134_01495	COG2186	Transcriptional regulator
FY134_01505	COG0583	DNA-binding transcription factor activity
FY134_01510	COG0277	FAD linked oxidase domain protein
FY134_01515	COG0277	FAD linked oxidase domain protein
FY134_01520	COG0247	lactate metabolic process
FY134_01530	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_01535	COG0519	Catalyzes the synthesis of GMP from XMP
FY134_01545	COG2855	membrane
FY134_01550	COG0583	DNA-binding transcription factor activity
FY134_01570	COG0124	histidyl-tRNA synthetase
FY134_01580	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY134_01585	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY134_01590	COG2259	Doxx family
FY134_01600	COG0459	protein refolding
FY134_01605	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY134_01615	COG0196	riboflavin kinase activity
FY134_01620	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY134_01630	COG0590	tRNA wobble adenosine to inosine editing
FY134_01635	COG1187	pseudouridine synthase activity
FY134_01640	COG0742	ribosomal rna small subunit methyltransferase
FY134_01645	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY134_01655	COG0312	modulator of DNA gyrase
FY134_01660	COG0483	inositol monophosphate 1-phosphatase activity
FY134_01670	COG1519	Transferase
FY134_01680	COG1663	tetraacyldisaccharide 4'-kinase activity
FY134_01690	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY134_01700	COG5001	Diguanylate cyclase
FY134_01700	COG3300	MHYT domain
FY134_01705	COG3386	PFAM SMP-30 Gluconolaconase
FY134_01710	COG0800	Aldolase
FY134_01715	COG3734	2-keto-3-deoxy-galactonokinase
FY134_01720	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_01730	COG2197	response regulator
FY134_01735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_01745	COG0598	Magnesium transport protein CorA
FY134_01750	COG3158	transport of potassium into the cell
FY134_01765	COG0356	it plays a direct role in the translocation of protons across the membrane
FY134_01775	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY134_01780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY134_01795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY134_01815	COG0009	L-threonylcarbamoyladenylate synthase
FY134_01825	COG4638	Rieske (2fe-2S)
FY134_01850	COG1960	acyl-CoA dehydrogenase activity
FY134_01865	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY134_01870	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY134_01875	COG0840	transmembrane signaling receptor activity
FY134_01885	COG1522	sequence-specific DNA binding
FY134_01915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY134_01920	COG1741	Belongs to the pirin family
FY134_01925	COG1722	exodeoxyribonuclease VII activity
FY134_01930	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY134_01935	COG1268	BioY protein
FY134_01940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY134_01945	COG1122	ATPase activity
FY134_01950	COG3214	Protein conserved in bacteria
FY134_01955	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY134_01955	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY134_01960	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY134_01975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY134_01990	COG0259	pyridoxamine-phosphate oxidase activity
FY134_02005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_02015	COG0312	modulator of DNA gyrase
FY134_02030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY134_02035	COG0109	protoheme IX farnesyltransferase activity
FY134_02040	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY134_02055	COG3346	SURF1 family
FY134_02060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY134_02065	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY134_02070	COG0328	RNA-DNA hybrid ribonuclease activity
FY134_02085	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY134_02085	COG0678	peroxiredoxin activity
FY134_02095	COG1678	Uncharacterized ACR, COG1678
FY134_02115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY134_02120	COG0612	Peptidase, M16
FY134_02145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_02150	COG1802	Transcriptional regulator
FY134_02165	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY134_02175	COG1194	a g-specific adenine glycosylase
FY134_02185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY134_02190	COG1196	nuclear chromosome segregation
FY134_02195	COG2514	catechol 2,3-dioxygenase activity
FY134_02200	COG0574	Belongs to the PEP-utilizing enzyme family
FY134_02200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY134_02215	COG1823	symporter activity
FY134_02235	COG1309	transcriptional regulator
FY134_02245	COG0579	oxidoreductase
FY134_02260	COG2895	sulfate adenylyltransferase (ATP) activity
FY134_02265	COG0175	sulfate reduction
FY134_02270	COG0175	sulfate reduction
FY134_02275	COG1959	2 iron, 2 sulfur cluster binding
FY134_02280	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY134_02285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY134_02290	COG4208	sulfate ABC transporter
FY134_02295	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY134_02305	COG2200	EAL domain
FY134_02305	COG2203	Gaf domain
FY134_02305	COG2199	diguanylate cyclase activity
FY134_02315	COG1309	transcriptional regulator
FY134_02320	COG1012	belongs to the aldehyde dehydrogenase family
FY134_02325	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY134_02360	COG0625	glutathione transferase activity
FY134_02370	COG0477	Major facilitator Superfamily
FY134_02380	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY134_02380	COG1793	dna ligase
FY134_02400	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_02405	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_02410	COG1846	Transcriptional regulator
FY134_02415	COG1764	response to oxidative stress
FY134_02430	COG0488	(ABC) transporter
FY134_02465	COG4221	oxidoreductase activity
FY134_02480	COG0433	COG0433 Predicted ATPase
FY134_02495	COG1733	regulation of RNA biosynthetic process
FY134_02500	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY134_02515	COG0656	L-ascorbic acid biosynthetic process
FY134_02520	COG2378	regulation of single-species biofilm formation
FY134_02530	COG4106	trans-aconitate 2-methyltransferase activity
FY134_02535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY134_02540	COG0840	transmembrane signaling receptor activity
FY134_02545	COG0583	DNA-binding transcription factor activity
FY134_02560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY134_02570	COG2378	regulation of single-species biofilm formation
FY134_02580	COG3909	cytochrome
FY134_02585	COG2010	Cytochrome c
FY134_02620	COG0789	Transcriptional regulator
FY134_02645	COG0517	IMP dehydrogenase activity
FY134_02645	COG4175	Glycine betaine
FY134_02650	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_02670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_02680	COG2169	Transcriptional regulator
FY134_02680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY134_02690	COG2514	catechol 2,3-dioxygenase activity
FY134_02710	COG1272	protein, Hemolysin III
FY134_02720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY134_02725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY134_02725	COG2111	Na H antiporter
FY134_02730	COG2111	Na H antiporter
FY134_02735	COG1006	Multisubunit Na H antiporter MnhC subunit
FY134_02740	COG0651	ATP synthesis coupled electron transport
FY134_02745	COG1863	multisubunit Na H antiporter MnhE subunit
FY134_02750	COG2212	antiporter activity
FY134_02755	COG1320	monovalent cation:proton antiporter activity
FY134_02760	COG4957	zinc ion binding
FY134_02775	COG2166	iron-sulfur cluster assembly
FY134_02785	COG2205	protein histidine kinase activity
FY134_02825	COG0583	DNA-binding transcription factor activity
FY134_02845	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY134_02850	COG2983	Belongs to the UPF0260 family
FY134_02865	COG2217	Heavy metal translocating P-type atpase
FY134_02900	COG1621	beta-fructofuranosidase activity
FY134_02905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY134_02955	COG4695	Portal protein
FY134_03170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY134_03270	COG4235	cytochrome complex assembly
FY134_03275	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY134_03280	COG1138	Cytochrome C-type biogenesis protein
FY134_03285	COG3088	subunit of a heme lyase
FY134_03290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY134_03305	COG3011	Protein conserved in bacteria
FY134_03315	COG3713	MltA-interacting MipA family protein
FY134_03320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY134_03325	COG2205	protein histidine kinase activity
FY134_03325	COG2202	Pas domain
FY134_03335	COG0308	aminopeptidase N
FY134_03340	COG0697	spore germination
FY134_03355	COG0443	Heat shock 70 kDa protein
FY134_03395	COG0604	alcohol dehydrogenase
FY134_03400	COG1733	regulation of RNA biosynthetic process
FY134_03405	COG1968	undecaprenyl-diphosphatase activity
FY134_03410	COG2239	Acts as a magnesium transporter
FY134_03415	COG2814	Major facilitator Superfamily
FY134_03445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY134_03475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY134_03520	COG0741	lytic transglycosylase activity
FY134_03530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_03535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY134_03540	COG0840	transmembrane signaling receptor activity
FY134_03550	COG1758	RNA polymerase activity
FY134_03570	COG0736	holo-[acyl-carrier-protein] synthase activity
FY134_03575	COG0681	Belongs to the peptidase S26 family
FY134_03580	COG0571	ribonuclease III activity
FY134_03585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY134_03590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY134_03595	COG0784	Response regulator, receiver
FY134_03600	COG1381	Involved in DNA repair and RecF pathway recombination
FY134_03610	COG2226	methyltransferase
FY134_03620	COG1418	mRNA catabolic process
FY134_03630	COG0346	lactoylglutathione lyase activity
FY134_03645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_03650	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY134_03655	COG0668	transmembrane transport
FY134_03665	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY134_03690	COG1051	belongs to the nudix hydrolase family
FY134_03695	COG1742	UPF0060 membrane protein
FY134_03710	COG1183	phosphatidylcholine synthase activity
FY134_03715	COG0688	phosphatidylethanolamine metabolic process
FY134_03720	COG5265	(ABC) transporter
FY134_03760	COG2852	Protein conserved in bacteria
FY134_03765	COG0215	cysteine-tRNA ligase activity
FY134_03770	COG4221	oxidoreductase activity
FY134_03775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY134_03780	COG1286	toxin biosynthetic process
FY134_03800	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY134_03810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY134_03820	COG0305	Participates in initiation and elongation during chromosome replication
FY134_03840	COG0359	binds to the 23S rRNA
FY134_03850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY134_03855	COG0360	Binds together with S18 to 16S ribosomal RNA
FY134_03860	COG0667	Aldo Keto reductase
FY134_03865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY134_03875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY134_03880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY134_03885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY134_03890	COG1561	YicC-like family, N-terminal region
FY134_03895	COG0194	GDP metabolic process
FY134_03900	COG0400	carboxylic ester hydrolase activity
FY134_03905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY134_03910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY134_03920	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY134_03935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY134_03955	COG3300	MHYT domain
FY134_03955	COG5001	Diguanylate cyclase
FY134_03960	COG4191	Histidine kinase
FY134_03975	COG0488	(ABC) transporter
FY134_03980	COG3706	GGDEF domain
FY134_03990	COG0105	UTP biosynthetic process
FY134_04010	COG0314	molybdopterin synthase activity
FY134_04015	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FY134_04020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY134_04025	COG0322	excinuclease ABC activity
FY134_04030	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_04040	COG0625	glutathione transferase activity
FY134_04060	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY134_04065	COG0243	molybdopterin cofactor binding
FY134_04080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY134_04085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY134_04090	COG0628	permease
FY134_04100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY134_04105	COG0248	Ppx GppA phosphatase
FY134_04130	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY134_04140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY134_04145	COG0477	Major facilitator Superfamily
FY134_04150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY134_04160	COG4452	Inner membrane protein CreD
FY134_04165	COG0659	secondary active sulfate transmembrane transporter activity
FY134_04175	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY134_04180	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY134_04190	COG0113	porphobilinogen synthase activity
FY134_04210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY134_04215	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY134_04220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY134_04220	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY134_04230	COG1280	lysine exporter protein (LysE YggA)
FY134_04235	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY134_04240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY134_04245	COG2814	Major facilitator Superfamily
FY134_04250	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY134_04270	COG0416	fatty acid biosynthetic process
FY134_04275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY134_04280	COG0776	regulation of translation
FY134_04315	COG0601	transmembrane transport
FY134_04320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_04325	COG0444	Belongs to the ABC transporter superfamily
FY134_04335	COG0747	negative chemotaxis
FY134_04345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY134_04350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY134_04365	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY134_04370	COG0583	DNA-binding transcription factor activity
FY134_04375	COG0737	Belongs to the 5'-nucleotidase family
FY134_04400	COG2897	thiosulfate sulfurtransferase activity
FY134_04415	COG0415	Belongs to the DNA photolyase family
FY134_04425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY134_04455	COG3932	Exopolysaccharide synthesis, ExoD
FY134_04560	COG4626	Terminase
FY134_04560	COG1802	Transcriptional regulator
FY134_04630	COG0297	glycogen (starch) synthase activity
FY134_04655	COG1612	heme a metabolic process
FY134_04665	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY134_04670	COG0010	Belongs to the arginase family
FY134_04675	COG1396	sequence-specific DNA binding
FY134_04680	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FY134_04685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY134_04690	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY134_04700	COG1832	CoA-binding protein
FY134_04730	COG2124	cytochrome p450
FY134_04735	COG2199	diguanylate cyclase activity
FY134_04740	COG0740	serine-type endopeptidase activity
FY134_04745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY134_04750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY134_04760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY134_04790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_04795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_04800	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_04810	COG0649	NAD binding
FY134_04820	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY134_04825	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY134_04835	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY134_04840	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY134_04850	COG0713	ATP synthesis coupled electron transport
FY134_04865	COG1007	ATP synthesis coupled electron transport
FY134_04870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY134_04870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY134_04885	COG0442	prolyl-tRNA aminoacylation
FY134_04895	COG1136	(ABC) transporter
FY134_04910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY134_04930	COG0784	Response regulator, receiver
FY134_04940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY134_04945	COG0477	Major facilitator Superfamily
FY134_04960	COG0557	exoribonuclease II activity
FY134_04965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY134_04975	COG0758	DNA mediated transformation
FY134_04980	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY134_04990	COG0540	Belongs to the ATCase OTCase family
FY134_05000	COG1960	acyl-CoA dehydrogenase activity
FY134_05005	COG0456	acetyltransferase
FY134_05035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY134_05040	COG2824	Alkylphosphonate utilization operon protein PhnA
FY134_05045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY134_05050	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY134_05055	COG0154	amidase activity
FY134_05060	COG3811	Belongs to the UPF0386 family
FY134_05075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY134_05085	COG0456	acetyltransferase
FY134_05100	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY134_05105	COG0439	Biotin carboxylase
FY134_05110	COG0511	ligase activity, forming carbon-carbon bonds
FY134_05115	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY134_05125	COG0436	Aminotransferase
FY134_05145	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_05150	COG1530	ribonuclease E activity
FY134_05160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY134_05180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY134_05185	COG0384	phenazine biosynthesis protein PhzF
FY134_05200	COG0633	Ferredoxin
FY134_05210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FY134_05215	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY134_05220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY134_05230	COG3768	UPF0283 membrane protein
FY134_05235	COG3106	COG3106 Predicted ATPase
FY134_05265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY134_05295	COG0537	adenosine 5'-monophosphoramidase activity
FY134_05320	COG0052	Belongs to the universal ribosomal protein uS2 family
FY134_05325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY134_05330	COG0528	UMP kinase activity
FY134_05335	COG0233	cytoplasmic translational termination
FY134_05340	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY134_05350	COG0750	zinc metalloprotease
FY134_05355	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY134_05360	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY134_05365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY134_05370	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY134_05375	COG3494	Protein of unknown function (DUF1009)
FY134_05380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY134_05385	COG2186	Transcriptional regulator
FY134_05395	COG0765	amino acid transport
FY134_05400	COG0765	amino acid transport
FY134_05410	COG0372	Belongs to the citrate synthase family
FY134_05425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY134_05430	COG4598	ABC transporter
FY134_05435	COG0765	amino acid transport
FY134_05440	COG0765	amino acid transport
FY134_05445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_05450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_05455	COG3842	ATPase activity
FY134_05460	COG0395	ABC-type sugar transport system, permease component
FY134_05470	COG2182	Extracellular solute-binding protein
FY134_05480	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_05485	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_05490	COG1063	alcohol dehydrogenase
FY134_05495	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY134_05515	COG0683	leucine binding
FY134_05520	COG1960	acyl-CoA dehydrogenase activity
FY134_05535	COG1024	Enoyl-CoA hydratase
FY134_05550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_05570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY134_05575	COG0148	phosphopyruvate hydratase activity
FY134_05585	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY134_05590	COG0022	dehydrogenase e1 component
FY134_05590	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY134_05600	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY134_05610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY134_05620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY134_05625	COG0697	spore germination
FY134_05640	COG2867	negative regulation of translational initiation
FY134_05645	COG1546	Belongs to the CinA family
FY134_05650	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY134_05650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY134_05660	COG3852	Histidine kinase
FY134_05665	COG2204	response regulator
FY134_05670	COG5000	phosphorelay sensor kinase activity
FY134_05675	COG2204	response regulator
FY134_05680	COG0569	domain protein
FY134_05685	COG1923	regulation of RNA biosynthetic process
FY134_05690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY134_05695	COG3956	TIGRFAM MazG family protein
FY134_05705	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY134_05705	COG1648	precorrin-2 dehydrogenase activity
FY134_05720	COG0275	rRNA processing
FY134_05745	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY134_05745	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY134_05750	COG0509	glycine decarboxylation via glycine cleavage system
FY134_05755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_05780	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY134_05805	COG0251	oxidation-reduction process
FY134_05810	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY134_05820	COG1671	Belongs to the UPF0178 family
FY134_05830	COG0450	alkyl hydroperoxide reductase
FY134_05870	COG2826	transposase and inactivated derivatives, IS30 family
FY134_05875	COG0431	NADPH-dependent FMN reductase
FY134_05885	COG0798	PFAM Bile acid sodium symporter
FY134_05905	COG0321	lipoyl(octanoyl) transferase activity
FY134_05905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY134_05910	COG0084	hydrolase, TatD family'
FY134_05915	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY134_05925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY134_05975	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY134_05980	COG2095	MarC family integral membrane protein
FY134_05985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY134_05985	COG0517	IMP dehydrogenase activity
FY134_05985	COG0617	tRNA 3'-terminal CCA addition
FY134_05995	COG3609	addiction module antidote protein, CC2985 family
FY134_06000	COG0629	single-stranded DNA binding
FY134_06005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY134_06015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY134_06020	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY134_06035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY134_06040	COG1121	(ABC) transporter
FY134_06060	COG0667	Aldo Keto reductase
FY134_06070	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY134_06140	COG0668	transmembrane transport
FY134_06165	COG2239	Acts as a magnesium transporter
FY134_06170	COG0243	molybdopterin cofactor binding
FY134_06180	COG0242	peptide deformylase activity
FY134_06200	COG0321	lipoyl(octanoyl) transferase activity
FY134_06205	COG1064	alcohol dehydrogenase
FY134_06235	COG1862	Preprotein translocase
FY134_06260	COG2124	cytochrome p450
FY134_06280	COG0596	Alpha beta hydrolase
FY134_06290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_06295	COG0626	cystathionine gamma-synthase activity
FY134_06300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_06305	COG4597	amino acid ABC transporter
FY134_06310	COG0765	amino acid transport
FY134_06315	COG1126	abc transporter atp-binding protein
FY134_06330	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY134_06345	COG0436	Aminotransferase
FY134_06375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY134_06385	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY134_06390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY134_06395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY134_06410	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY134_06415	COG1489	DNA binding
FY134_06420	COG0024	Methionine aminopeptidase
FY134_06425	COG2003	Belongs to the UPF0758 family
FY134_06440	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY134_06460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY134_06465	COG0546	phosphoglycolate phosphatase activity
FY134_06480	COG0114	fumarate hydratase activity
FY134_06490	COG0504	CTP synthase activity
FY134_06500	COG0149	triose-phosphate isomerase activity
FY134_06510	COG0187	DNA topoisomerase II activity
FY134_06520	COG1309	transcriptional regulator
FY134_06525	COG2226	methyltransferase
FY134_06535	COG0740	serine-type endopeptidase activity
FY134_06545	COG0640	Transcriptional regulator
FY134_06550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY134_06555	COG0745	RESPONSE REGULATOR receiver
FY134_06565	COG3264	Mechanosensitive ion channel
FY134_06565	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY134_06635	COG1127	ABC transporter
FY134_06640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY134_06645	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_06660	COG0280	phosphate acetyltransferase
FY134_06660	COG0281	malic enzyme
FY134_06670	COG0778	Nitroreductase
FY134_06675	COG0823	Involved in the tonB-independent uptake of proteins
FY134_06685	COG1368	sulfuric ester hydrolase activity
FY134_06710	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY134_06730	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY134_06735	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY134_06770	COG0343	queuine tRNA-ribosyltransferase activity
FY134_06775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY134_06790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY134_06805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY134_06810	COG0134	indole-3-glycerol-phosphate synthase activity
FY134_06815	COG0315	cyclic pyranopterin monophosphate synthase activity
FY134_06820	COG0303	'Molybdopterin
FY134_06825	COG3706	GGDEF domain
FY134_06835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY134_06835	COG0475	glutathione-regulated potassium exporter activity
FY134_06845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY134_06850	COG0697	spore germination
FY134_06855	COG2814	Major facilitator Superfamily
FY134_06860	COG0746	molybdenum cofactor guanylyltransferase activity
FY134_06865	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY134_06870	COG0739	heme binding
FY134_06875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY134_06880	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY134_06885	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY134_06890	COG0805	protein transport
FY134_06895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY134_06900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY134_06905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY134_06910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY134_06915	COG1472	Belongs to the glycosyl hydrolase 3 family
FY134_06925	COG0018	arginyl-trna synthetase
FY134_06930	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY134_06935	COG0316	Belongs to the HesB IscA family
FY134_06945	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FY134_06960	COG0525	valine-tRNA ligase activity
FY134_06970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY134_07005	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY134_07010	COG1058	Belongs to the CinA family
FY134_07010	COG1546	Belongs to the CinA family
FY134_07015	COG0589	response to stress
FY134_07020	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY134_07025	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY134_07085	COG0084	hydrolase, TatD family'
FY134_07115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_07135	COG1914	H( )-stimulated, divalent metal cation uptake system
FY134_07145	COG1132	(ABC) transporter
FY134_07150	COG0628	permease
FY134_07170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_07185	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY134_07195	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY134_07205	COG0302	gtp cyclohydrolase
FY134_07210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY134_07215	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY134_07220	COG0516	GMP reductase activity
FY134_07220	COG0517	IMP dehydrogenase activity
FY134_07250	COG1760	l-serine dehydratase
FY134_07285	COG0583	DNA-binding transcription factor activity
FY134_07300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY134_07300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY134_07310	COG0347	Belongs to the P(II) protein family
FY134_07315	COG0174	glutamine synthetase
FY134_07345	COG0697	spore germination
FY134_07355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY134_07365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY134_07395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY134_07400	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY134_07405	COG2186	Transcriptional regulator
FY134_07415	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_07420	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY134_07425	COG3845	ABC transporter
FY134_07430	COG1183	phosphatidylcholine synthase activity
FY134_07435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_07440	COG0679	Auxin Efflux Carrier
FY134_07445	COG0785	Cytochrome C biogenesis protein
FY134_07475	COG1278	Cold shock
FY134_07525	COG2267	carboxylic ester hydrolase activity
FY134_07535	COG0577	efflux transmembrane transporter activity
FY134_07535	COG1136	(ABC) transporter
FY134_07540	COG0577	efflux transmembrane transporter activity
FY134_07540	COG1136	(ABC) transporter
FY134_07555	COG2151	metal-sulfur cluster biosynthetic enzyme
FY134_07560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY134_07565	COG0719	Fe-S assembly protein
FY134_07570	COG0396	ATPase activity
FY134_07580	COG0719	Fe-S assembly protein
FY134_07585	COG1104	cysteine desulfurase activity
FY134_07590	COG2945	thiolester hydrolase activity
FY134_07595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY134_07600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY134_07610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY134_07615	COG2833	Protein of unknown function (DUF455)
FY134_07620	COG0739	heme binding
FY134_07625	COG0513	Belongs to the DEAD box helicase family
FY134_07655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY134_07665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY134_07670	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY134_07675	COG0047	phosphoribosylformylglycinamidine synthase activity
FY134_07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_07700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY134_07720	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY134_07725	COG2814	Major facilitator Superfamily
FY134_07730	COG0483	inositol monophosphate 1-phosphatase activity
FY134_07735	COG0483	inositol monophosphate 1-phosphatase activity
FY134_07740	COG0037	tRNA processing
FY134_07745	COG2066	Belongs to the glutaminase family
FY134_07750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY134_07755	COG0861	Integral membrane protein TerC family
FY134_07770	COG1280	lysine exporter protein (LysE YggA)
FY134_07780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY134_07785	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY134_07795	COG0538	isocitrate dehydrogenase activity
FY134_07810	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY134_07815	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY134_07820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_07825	COG2313	pseudouridylate synthase activity
FY134_07835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_07840	COG4215	(ABC) transporter
FY134_07850	COG5425	PFAM Usg family protein
FY134_07860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_07865	COG1522	sequence-specific DNA binding
FY134_07870	COG1573	uracil-dna glycosylase
FY134_07880	COG2202	Pas domain
FY134_07880	COG2205	protein histidine kinase activity
FY134_07890	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY134_07895	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY134_07910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY134_07920	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_07925	COG1129	ABC transporter
FY134_07935	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_07940	COG3959	Transketolase, thiamine diphosphate binding domain
FY134_07945	COG3958	Transketolase
FY134_07950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY134_07955	COG2390	Transcriptional regulator
FY134_07965	COG0842	Transport permease protein
FY134_07970	COG1131	(ABC) transporter
FY134_08000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY134_08005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY134_08020	COG0129	dihydroxy-acid dehydratase activity
FY134_08025	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY134_08030	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY134_08040	COG0203	ribosomal protein L17
FY134_08045	COG0202	RNA polymerase activity
FY134_08050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY134_08055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY134_08060	COG0563	adenylate kinase activity
FY134_08065	COG0201	protein transport
FY134_08070	COG0200	Binds to the 23S rRNA
FY134_08075	COG1841	ribosomal large subunit assembly
FY134_08080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY134_08085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY134_08090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY134_08095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY134_08100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY134_08105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY134_08110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY134_08115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY134_08120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY134_08125	COG0255	Belongs to the universal ribosomal protein uL29 family
FY134_08130	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY134_08135	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY134_08140	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY134_08145	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY134_08150	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY134_08155	COG0089	rRNA binding
FY134_08160	COG0088	Forms part of the polypeptide exit tunnel
FY134_08165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY134_08170	COG0051	transcription antitermination factor activity, RNA binding
FY134_08175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY134_08180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY134_08185	COG0049	tRNA binding
FY134_08190	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY134_08210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY134_08215	COG0085	RNA polymerase activity
FY134_08220	COG0222	ribosome binding
FY134_08225	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY134_08230	COG0081	regulation of translation
FY134_08235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY134_08245	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY134_08255	COG1086	Polysaccharide biosynthesis protein
FY134_08260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY134_08265	COG0861	Integral membrane protein TerC family
FY134_08275	COG3895	Periplasmic Protein
FY134_08295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY134_08315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY134_08350	COG0784	Response regulator, receiver
FY134_08350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_08350	COG2198	Histidine kinase
FY134_08350	COG2205	protein histidine kinase activity
FY134_08355	COG0784	Response regulator, receiver
FY134_08360	COG3920	Histidine kinase
FY134_08360	COG2202	Pas domain
FY134_08365	COG0784	Response regulator, receiver
FY134_08370	COG4251	negative regulation of phosphorylation
FY134_08385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY134_08415	COG2910	NAD(P)H-binding
FY134_08420	COG1733	regulation of RNA biosynthetic process
FY134_08425	COG0556	nucleotide-excision repair
FY134_08430	COG2382	esterase
FY134_08450	COG0484	heat shock protein binding
FY134_08465	COG3706	GGDEF domain
FY134_08475	COG3842	ATPase activity
FY134_08485	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_08490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_08500	COG4115	mRNA cleavage
FY134_08510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY134_08520	COG2207	Transcriptional regulator
FY134_08525	COG1064	alcohol dehydrogenase
FY134_08530	COG1252	NADH dehydrogenase
FY134_08535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY134_08540	COG2197	response regulator
FY134_08545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY134_08575	COG0656	L-ascorbic acid biosynthetic process
FY134_08590	COG0440	acetolactate synthase activity
FY134_08595	COG0028	Belongs to the TPP enzyme family
FY134_08605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY134_08610	COG3830	Belongs to the UPF0237 family
FY134_08610	COG0560	Phosphoserine phosphatase
FY134_08620	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_08630	COG0330	HflC and HflK could
FY134_08635	COG0330	HflC and HflK could
FY134_08645	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY134_08680	COG0277	FAD linked oxidase domain protein
FY134_08685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY134_08740	COG1335	isochorismatase
FY134_08760	COG0006	proline dipeptidase activity
FY134_08765	COG2264	protein methyltransferase activity
FY134_08770	COG1999	signal sequence binding
FY134_08780	COG0835	chemotaxis
FY134_08795	COG0583	DNA-binding transcription factor activity
FY134_08805	COG1247	-acetyltransferase
FY134_08815	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY134_08820	COG0497	DNA recombination
FY134_08825	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY134_08835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY134_08840	COG0849	cell division
FY134_08845	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY134_08850	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY134_08855	COG0477	Major facilitator Superfamily
FY134_08860	COG3300	MHYT domain
FY134_08860	COG5001	Diguanylate cyclase
FY134_08865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY134_08870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY134_08875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY134_08885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY134_08890	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY134_08900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY134_08915	COG0275	rRNA processing
FY134_08920	COG2001	Belongs to the MraZ family
FY134_08945	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY134_08975	COG4106	trans-aconitate 2-methyltransferase activity
FY134_08995	COG2226	methyltransferase
FY134_09005	COG2267	carboxylic ester hydrolase activity
FY134_09010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY134_09025	COG0251	oxidation-reduction process
FY134_09040	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_09045	COG2814	Major facilitator Superfamily
FY134_09070	COG1012	belongs to the aldehyde dehydrogenase family
FY134_09085	COG0174	glutamine synthetase
FY134_09090	COG0531	amino acid
FY134_09100	COG1737	Transcriptional regulator
FY134_09120	COG3842	ATPase activity
FY134_09180	COG2968	Membrane
FY134_09205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY134_09210	COG0358	DNA primase activity
FY134_09230	COG0505	Belongs to the CarA family
FY134_09245	COG0534	Mate efflux family protein
FY134_09260	COG2321	neutral zinc metallopeptidase
FY134_09275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY134_09280	COG3706	GGDEF domain
FY134_09295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY134_09305	COG1522	sequence-specific DNA binding
FY134_09310	COG0492	ferredoxin-NADP+ reductase activity
FY134_09315	COG0583	DNA-binding transcription factor activity
FY134_09325	COG1902	pentaerythritol trinitrate reductase activity
FY134_09350	COG0387	Pfam Sodium calcium exchanger
FY134_09355	COG0436	Aminotransferase
FY134_09360	COG2199	diguanylate cyclase activity
FY134_09360	COG2200	EAL domain
FY134_09375	COG1278	Cold shock
FY134_09380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_09390	COG1846	Transcriptional regulator
FY134_09395	COG0745	RESPONSE REGULATOR receiver
FY134_09400	COG2205	protein histidine kinase activity
FY134_09405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY134_09425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY134_09435	COG1496	oxidoreductase activity
FY134_09450	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY134_09460	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY134_09475	COG0840	transmembrane signaling receptor activity
FY134_09480	COG1012	belongs to the aldehyde dehydrogenase family
FY134_09485	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY134_09490	COG5001	Diguanylate cyclase
FY134_09490	COG3300	MHYT domain
FY134_09495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY134_09500	COG5001	Diguanylate cyclase
FY134_09510	COG0193	aminoacyl-tRNA hydrolase activity
FY134_09520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY134_09540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY134_09545	COG2857	Cytochrome c1
FY134_09545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY134_09565	COG1132	(ABC) transporter
FY134_09570	COG1132	(ABC) transporter
FY134_09575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY134_09580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY134_09595	COG0408	coproporphyrinogen oxidase activity
FY134_09610	COG0617	tRNA 3'-terminal CCA addition
FY134_09625	COG0714	Associated with various cellular activities
FY134_09645	COG0454	-acetyltransferase
FY134_09650	COG0477	Major facilitator Superfamily
FY134_09660	COG0435	Glutathione S-transferase
FY134_09665	COG0494	nUDIX hydrolase
FY134_09675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY134_09690	COG3135	benzoate transporter
FY134_09705	COG1595	DNA-templated transcription, initiation
FY134_09715	COG0740	serine-type endopeptidase activity
FY134_09730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY134_09735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY134_09760	COG4175	Glycine betaine
FY134_09775	COG1435	thymidine kinase activity
FY134_09795	COG2862	Uncharacterized protein family, UPF0114
FY134_09800	COG1629	transport
FY134_09800	COG4771	TonB-dependent receptor
FY134_09810	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY134_09810	COG0512	Glutamine amidotransferase of anthranilate synthase
FY134_09825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY134_09840	COG0366	Alpha amylase catalytic
FY134_09845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_09865	COG1160	GTP binding
FY134_09885	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY134_09895	COG0024	Methionine aminopeptidase
FY134_09905	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_09915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY134_09925	COG0583	DNA-binding transcription factor activity
FY134_09940	COG0402	S-adenosylhomocysteine deaminase activity
FY134_09955	COG1304	FMN binding
FY134_09965	COG1309	transcriptional regulator
FY134_09970	COG1686	Belongs to the peptidase S11 family
FY134_09980	COG2351	hydroxyisourate hydrolase activity
FY134_09985	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY134_10000	COG3195	allantoin biosynthetic process
FY134_10000	COG3648	Uricase
FY134_10010	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY134_10020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_10020	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY134_10030	COG0513	Belongs to the DEAD box helicase family
FY134_10035	COG0697	spore germination
FY134_10040	COG2259	Doxx family
FY134_10045	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_10055	COG2308	Evidence 4 Homologs of previously reported genes of
FY134_10065	COG1305	Transglutaminase-like
FY134_10080	COG0456	acetyltransferase
FY134_10095	COG4214	carbohydrate transport
FY134_10100	COG1129	ABC transporter
FY134_10105	COG4213	ABC transporter substrate-binding protein
FY134_10225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY134_10235	COG0840	transmembrane signaling receptor activity
FY134_10240	COG2814	Major facilitator Superfamily
FY134_10245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY134_10245	COG0646	methionine synthase
FY134_10255	COG4215	(ABC) transporter
FY134_10260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_10285	COG1215	transferase activity, transferring glycosyl groups
FY134_10315	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY134_10320	COG2346	COG2346, Truncated hemoglobins
FY134_10340	COG1309	transcriptional regulator
FY134_10355	COG0494	nUDIX hydrolase
FY134_10365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_10370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_10395	COG1234	tRNA 3'-trailer cleavage
FY134_10400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY134_10405	COG0830	nickel cation binding
FY134_10410	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY134_10425	COG0804	urea catabolic process
FY134_10430	COG1442	glycosyl transferase family 8
FY134_10435	COG3755	Protein conserved in bacteria
FY134_10445	COG0832	Belongs to the urease beta subunit family
FY134_10450	COG3813	Protein conserved in bacteria
FY134_10455	COG0831	urea catabolic process
FY134_10460	COG0829	nickel cation binding
FY134_10475	COG0411	ABC transporter
FY134_10485	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY134_10500	COG0174	glutamine synthetase
FY134_10505	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_10510	COG2198	Histidine kinase
FY134_10510	COG5002	protein histidine kinase activity
FY134_10510	COG0784	Response regulator, receiver
FY134_10560	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY134_10635	COG0564	pseudouridine synthase activity
FY134_10645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY134_10655	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY134_10680	COG0346	lactoylglutathione lyase activity
FY134_10690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY134_10700	COG2832	Protein of unknown function (DUF454)
FY134_10705	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY134_10710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_10715	COG4558	Periplasmic binding protein
FY134_10725	COG3721	Heme iron utilization protein
FY134_10740	COG2205	protein histidine kinase activity
FY134_10780	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_10785	COG4605	iron ion homeostasis
FY134_10790	COG4604	ABC transporter, ATP-binding protein
FY134_10795	COG0783	Belongs to the Dps family
FY134_10810	COG0583	DNA-binding transcription factor activity
FY134_10815	COG0657	acetylesterase activity
FY134_10820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_10840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY134_10845	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY134_10850	COG0288	reversible hydration of carbon dioxide
FY134_10860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY134_10880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY134_10885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_10890	COG0778	Nitroreductase
FY134_10895	COG2267	carboxylic ester hydrolase activity
FY134_10900	COG0251	oxidation-reduction process
FY134_10905	COG1335	isochorismatase
FY134_10910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_10920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_10930	COG1653	transport
FY134_10935	COG1175	transmembrane transport
FY134_10940	COG0395	ABC-type sugar transport system, permease component
FY134_10945	COG3842	ATPase activity
FY134_10950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_10960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY134_10975	COG4608	Belongs to the ABC transporter superfamily
FY134_10980	COG0444	Belongs to the ABC transporter superfamily
FY134_10985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_10990	COG0601	transmembrane transport
FY134_11010	COG0392	lysyltransferase activity
FY134_11010	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FY134_11050	COG2159	amidohydrolase
FY134_11055	COG1960	acyl-CoA dehydrogenase activity
FY134_11085	COG0745	RESPONSE REGULATOR receiver
FY134_11095	COG1902	pentaerythritol trinitrate reductase activity
FY134_11095	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_11135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY134_11145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_11150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY134_11160	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY134_11170	COG1509	lysine 2,3-aminomutase activity
FY134_11185	COG0583	DNA-binding transcription factor activity
FY134_11190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_11195	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY134_11200	COG4149	molybdate abc transporter
FY134_11205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY134_11215	COG3191	aminopeptidase activity
FY134_11220	COG2022	thiamine diphosphate biosynthetic process
FY134_11235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY134_11240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY134_11250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY134_11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY134_11300	COG0438	transferase activity, transferring glycosyl groups
FY134_11320	COG4166	transmembrane transport
FY134_11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_11340	COG0438	transferase activity, transferring glycosyl groups
FY134_11345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY134_11350	COG3142	Participates in the control of copper homeostasis
FY134_11370	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_11375	COG1737	Transcriptional regulator
FY134_11385	COG3842	ATPase activity
FY134_11395	COG0395	ABC-type sugar transport system, permease component
FY134_11400	COG1175	transmembrane transport
FY134_11410	COG2188	Transcriptional regulator
FY134_11415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY134_11420	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY134_11425	COG1940	carbohydrate kinase activity
FY134_11435	COG0671	phosphoesterase, PA-phosphatase related
FY134_11440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY134_11445	COG0156	8-amino-7-oxononanoate synthase activity
FY134_11455	COG0729	surface antigen
FY134_11465	COG0835	chemotaxis
FY134_11475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY134_11480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY134_11485	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY134_11490	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY134_11495	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY134_11500	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY134_11515	COG4974	Belongs to the 'phage' integrase family
FY134_11540	COG1280	lysine exporter protein (LysE YggA)
FY134_11550	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY134_11560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY134_11565	COG0045	succinate-CoA ligase (ADP-forming) activity
FY134_11570	COG0039	L-malate dehydrogenase activity
FY134_11575	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY134_11610	COG2264	protein methyltransferase activity
FY134_11625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY134_11630	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY134_11635	COG0181	hydroxymethylbilane synthase activity
FY134_11675	COG1872	DUF167
FY134_11680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY134_11695	COG1217	gtp-binding protein TYPA
FY134_11700	COG0339	signal peptide processing
FY134_11705	COG1846	Transcriptional regulator
FY134_11715	COG0137	argininosuccinate synthase activity
FY134_11725	COG1280	lysine exporter protein (LysE YggA)
FY134_11730	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY134_11735	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY134_11745	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY134_11760	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY134_11765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY134_11770	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY134_11780	COG4181	ATPase activity
FY134_11790	COG0670	Belongs to the BI1 family
FY134_11805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY134_11810	COG4133	protoheme IX ABC transporter activity
FY134_11815	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY134_11820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY134_11845	COG2917	probably involved in intracellular septation
FY134_11850	COG0552	protein localization to endoplasmic reticulum
FY134_11855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY134_11860	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY134_11870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY134_11875	COG0287	Prephenate dehydrogenase
FY134_11875	COG1605	Chorismate mutase
FY134_11880	COG0228	four-way junction DNA binding
FY134_11885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY134_11890	COG0336	Belongs to the RNA methyltransferase TrmD family
FY134_11900	COG0335	large ribosomal subunit rRNA binding
FY134_11905	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY134_11910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_11925	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY134_11935	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY134_11955	COG0488	(ABC) transporter
FY134_11965	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY134_11975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY134_11980	COG0142	geranyltranstransferase activity
FY134_11985	COG2885	chlorophyll binding
FY134_11990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY134_11995	COG2223	nitrite transmembrane transporter activity
FY134_12000	COG1349	DNA-binding transcription factor activity
FY134_12005	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY134_12010	COG2197	response regulator
FY134_12015	COG1132	(ABC) transporter
FY134_12025	COG3459	Glycosyltransferase 36 associated
FY134_12030	COG1473	amidohydrolase
FY134_12035	COG0579	oxidoreductase
FY134_12045	COG0129	dihydroxy-acid dehydratase activity
FY134_12050	COG2084	Dehydrogenase
FY134_12055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_12060	COG0277	FAD linked oxidase domain protein
FY134_12065	COG2186	Transcriptional regulator
FY134_12075	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY134_12080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_12085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_12090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY134_12100	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY134_12105	COG0495	leucyl-tRNA aminoacylation
FY134_12120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY134_12135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_12140	COG1946	Acyl-CoA thioesterase
FY134_12145	COG0347	Belongs to the P(II) protein family
FY134_12150	COG0004	ammonium transporteR
FY134_12155	COG1674	ftsk spoiiie
FY134_12160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY134_12175	COG0745	RESPONSE REGULATOR receiver
FY134_12185	COG1329	Transcriptional regulator
FY134_12190	COG2902	Dehydrogenase
FY134_12195	COG2270	Major facilitator Superfamily
FY134_12210	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_12225	COG0494	nUDIX hydrolase
FY134_12235	COG0793	Belongs to the peptidase S41A family
FY134_12245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY134_12250	COG0799	negative regulation of ribosome biogenesis
FY134_12255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY134_12260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY134_12265	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY134_12270	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY134_12285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY134_12290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY134_12315	COG0066	3-isopropylmalate dehydratase activity
FY134_12320	COG0473	3-isopropylmalate dehydrogenase activity
FY134_12325	COG1858	cytochrome C peroxidase
FY134_12330	COG1797	cobyrinic acid a,c-diamide synthase activity
FY134_12335	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY134_12335	COG1648	precorrin-2 dehydrogenase activity
FY134_12340	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY134_12405	COG1492	cobalamin metabolic process
FY134_12420	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_12425	COG3254	rhamnose metabolic process
FY134_12430	COG0246	Mannitol dehydrogenase
FY134_12435	COG1063	alcohol dehydrogenase
FY134_12455	COG4214	carbohydrate transport
FY134_12460	COG1129	ABC transporter
FY134_12465	COG2186	Transcriptional regulator
FY134_12470	COG2721	sulfolactate sulfo-lyase activity
FY134_12475	COG0138	bifunctional purine biosynthesis protein purh
FY134_12485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY134_12485	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY134_12490	COG0501	Belongs to the peptidase M48B family
FY134_12510	COG0357	Ribosomal RNA small subunit methyltransferase G
FY134_12515	COG0445	tRNA wobble uridine modification
FY134_12520	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY134_12525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY134_12530	COG1981	membrane
FY134_12535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY134_12540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY134_12545	COG0424	maF-like protein
FY134_12550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_12555	COG0237	dephospho-CoA kinase activity
FY134_12565	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY134_12570	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY134_12580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY134_12605	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY134_12620	COG0135	phosphoribosylanthranilate isomerase activity
FY134_12625	COG0133	tryptophan synthase activity
FY134_12630	COG0159	tryptophan synthase activity
FY134_12635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY134_12650	COG1074	ATP-dependent DNA helicase activity
FY134_12660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY134_12670	COG2205	protein histidine kinase activity
FY134_12680	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY134_12685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY134_12690	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY134_12690	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY134_12695	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY134_12700	COG0642	Histidine kinase
FY134_12705	COG0745	RESPONSE REGULATOR receiver
FY134_12710	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY134_12720	COG1072	(Pantothenic acid kinase))
FY134_12725	COG0140	phosphoribosyl-ATP diphosphatase activity
FY134_12730	COG0107	imidazoleglycerol-phosphate synthase activity
FY134_12735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY134_12740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY134_12750	COG0131	Imidazoleglycerol-phosphate dehydratase
FY134_12755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY134_12760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY134_12770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY134_12785	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY134_12795	COG1643	Atp-dependent helicase
FY134_12835	COG0514	ATP-dependent DNA helicase (RecQ)
FY134_12860	COG1072	(Pantothenic acid kinase))
FY134_12870	COG1780	Probably involved in ribonucleotide reductase function
FY134_12890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY134_12920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_12930	COG2813	Specifically methylates the guanine in position
FY134_12935	COG1185	polyribonucleotide nucleotidyltransferase activity
FY134_12940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY134_12945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY134_12950	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY134_12955	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY134_12955	COG3064	Membrane
FY134_12970	COG0779	Required for maturation of 30S ribosomal subunits
FY134_12975	COG2814	Major facilitator Superfamily
FY134_12980	COG2951	lytic endotransglycosylase activity
FY134_12985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY134_12995	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY134_13000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY134_13015	COG2816	NAD+ diphosphatase activity
FY134_13020	COG0077	Prephenate dehydratase
FY134_13020	COG1605	Chorismate mutase
FY134_13025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY134_13030	COG3474	cytochrome
FY134_13040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY134_13045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY134_13055	COG1278	Cold shock
FY134_13065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY134_13080	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY134_13080	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY134_13090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY134_13120	COG2900	Belongs to the SlyX family
FY134_13130	COG0484	heat shock protein binding
FY134_13135	COG0443	Heat shock 70 kDa protein
FY134_13150	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY134_13155	COG1744	ABC transporter substrate-binding protein PnrA-like
FY134_13160	COG3845	ABC transporter
FY134_13165	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_13170	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_13175	COG0295	cytidine deaminase activity
FY134_13180	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY134_13185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY134_13190	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY134_13200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY134_13205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY134_13210	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY134_13220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY134_13225	COG1845	cytochrome c oxidase, subunit III
FY134_13230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY134_13240	COG0477	Major facilitator Superfamily
FY134_13245	COG0070	glutamate synthase
FY134_13245	COG0069	glutamate synthase activity
FY134_13245	COG0067	glutamate synthase
FY134_13250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY134_13265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY134_13275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY134_13305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_13325	COG0848	biopolymer transport protein
FY134_13335	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY134_13350	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY134_13355	COG3454	Phosphonate metabolism
FY134_13360	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY134_13365	COG3639	organic phosphonate transmembrane transporter activity
FY134_13370	COG3639	organic phosphonate transmembrane transporter activity
FY134_13375	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY134_13380	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY134_13390	COG4778	phosphonate C-P lyase system protein PhnL
FY134_13395	COG4107	phosphonate C-P lyase system protein PhnK
FY134_13400	COG3627	carbon phosphorus lyase activity
FY134_13405	COG3626	phosphonate metabolism
FY134_13410	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY134_13415	COG3624	Phosphonate C-P lyase system protein PhnG
FY134_13420	COG2188	Transcriptional regulator
FY134_13425	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY134_13430	COG0837	glucose binding
FY134_13435	COG1803	Methylglyoxal synthase
FY134_13440	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY134_13445	COG4166	transmembrane transport
FY134_13450	COG4174	ABC transporter (Permease)
FY134_13455	COG4239	(ABC) transporter, permease
FY134_13460	COG4172	Belongs to the ABC transporter superfamily
FY134_13465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_13470	COG0174	glutamine synthetase
FY134_13475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_13480	COG3265	gluconokinase activity
FY134_13485	COG1174	glycine betaine transport
FY134_13490	COG1125	glycine betaine transport
FY134_13495	COG1174	glycine betaine transport
FY134_13500	COG1732	Glycine betaine
FY134_13510	COG1959	2 iron, 2 sulfur cluster binding
FY134_13515	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_13535	COG0697	spore germination
FY134_13550	COG0791	NLP P60 protein
FY134_13560	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY134_13565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY134_13600	COG4964	Belongs to the GSP D family
FY134_13645	COG3422	double-strand break repair
FY134_13650	COG3757	hydrolase, family 25
FY134_13655	COG0697	spore germination
FY134_13660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_13690	COG0481	GTPase activity
FY134_13695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY134_13710	COG1396	sequence-specific DNA binding
FY134_13725	COG1917	Cupin 2, conserved barrel domain protein
FY134_13725	COG2169	Transcriptional regulator
FY134_13730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY134_13755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY134_13760	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY134_13765	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY134_13775	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY134_13780	COG0072	phenylalanine-tRNA ligase activity
FY134_13780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY134_13785	COG0667	Aldo Keto reductase
FY134_13800	COG0667	Aldo Keto reductase
FY134_13805	COG4977	sequence-specific DNA binding
FY134_13830	COG1570	exodeoxyribonuclease VII activity
FY134_13835	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_13845	COG1846	Transcriptional regulator
FY134_13850	COG0697	spore germination
FY134_13855	COG2309	aminopeptidase activity
FY134_13860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY134_13865	COG1393	Belongs to the ArsC family
FY134_13875	COG1309	transcriptional regulator
FY134_13885	COG0519	Catalyzes the synthesis of GMP from XMP
FY134_13885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY134_13900	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY134_13930	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY134_13940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY134_13950	COG1968	undecaprenyl-diphosphatase activity
FY134_13965	COG0284	orotidine-5'-phosphate decarboxylase activity
FY134_13975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY134_13985	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY134_13990	COG0792	nuclease activity
FY134_14005	COG1175	transmembrane transport
FY134_14010	COG0395	ABC-type sugar transport system, permease component
FY134_14015	COG3842	ATPase activity
FY134_14025	COG0189	ligase activity
FY134_14065	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY134_14120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_14135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY134_14140	COG1280	lysine exporter protein (LysE YggA)
FY134_14145	COG0756	dUTP diphosphatase activity
FY134_14150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY134_14155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY134_14170	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY134_14175	COG2226	methyltransferase
FY134_14180	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY134_14185	COG1024	Enoyl-CoA hydratase
FY134_14190	COG0268	Binds directly to 16S ribosomal RNA
FY134_14210	COG0640	Transcriptional regulator
FY134_14255	COG3842	ATPase activity
FY134_14260	COG4209	transmembrane transport
FY134_14265	COG0395	ABC-type sugar transport system, permease component
FY134_14270	COG1653	transport
FY134_14280	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_14290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_14300	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_14330	COG2197	response regulator
FY134_14335	COG0601	transmembrane transport
FY134_14340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_14360	COG0747	negative chemotaxis
FY134_14375	COG1446	asparaginase
FY134_14385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_14390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_14395	COG0601	transmembrane transport
FY134_14435	COG1215	transferase activity, transferring glycosyl groups
FY134_14445	COG0025	NhaP-type Na H and K H
FY134_14450	COG4178	(ABC) transporter
FY134_14460	COG1609	Transcriptional regulator
FY134_14475	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_14480	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FY134_14515	COG1794	racemase activity, acting on amino acids and derivatives
FY134_14520	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_14525	COG1309	transcriptional regulator
FY134_14530	COG2233	PERMEase
FY134_14570	COG1595	DNA-templated transcription, initiation
FY134_14580	COG0395	ABC-type sugar transport system, permease component
FY134_14585	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_14595	COG3842	ATPase activity
FY134_14630	COG1653	transport
FY134_14645	COG3842	ATPase activity
FY134_14650	COG0395	ABC-type sugar transport system, permease component
FY134_14655	COG1175	transmembrane transport
FY134_14685	COG1609	Transcriptional regulator
FY134_14695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_14700	COG1082	Xylose isomerase domain protein TIM barrel
FY134_14705	COG3842	ATPase activity
FY134_14710	COG0395	ABC-type sugar transport system, permease component
FY134_14715	COG1175	transmembrane transport
FY134_14720	COG1653	transport
FY134_14725	COG1309	transcriptional regulator
FY134_14730	COG0673	inositol 2-dehydrogenase activity
FY134_14745	COG0673	inositol 2-dehydrogenase activity
FY134_14750	COG1278	Cold shock
FY134_14760	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY134_14780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY134_14795	COG3842	ATPase activity
FY134_14800	COG0395	ABC-type sugar transport system, permease component
FY134_14805	COG1175	transmembrane transport
FY134_14825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_14830	COG3618	amidohydrolase
FY134_14835	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_14840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_14845	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_14850	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY134_14855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_14860	COG2186	Transcriptional regulator
FY134_14910	COG2223	nitrite transmembrane transporter activity
FY134_14915	COG0583	DNA-binding transcription factor activity
FY134_14920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_14930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_14950	COG1609	Transcriptional regulator
FY134_14955	COG1063	alcohol dehydrogenase
FY134_14960	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_14970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_14975	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY134_14980	COG1175	transmembrane transport
FY134_14985	COG0395	ABC-type sugar transport system, permease component
FY134_15000	COG0395	ABC-type sugar transport system, permease component
FY134_15005	COG1175	transmembrane transport
FY134_15010	COG2182	Extracellular solute-binding protein
FY134_15015	COG0626	cystathionine gamma-synthase activity
FY134_15025	COG0328	RNA-DNA hybrid ribonuclease activity
FY134_15030	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY134_15040	COG1121	(ABC) transporter
FY134_15045	COG0523	cobalamin synthesis protein
FY134_15060	COG0523	cobalamin synthesis protein
FY134_15065	COG1653	transport
FY134_15070	COG1175	transmembrane transport
FY134_15075	COG0395	ABC-type sugar transport system, permease component
FY134_15080	COG3842	ATPase activity
FY134_15095	COG3047	cAMP biosynthetic process
FY134_15120	COG0583	DNA-binding transcription factor activity
FY134_15125	COG1879	ABC-type sugar transport system periplasmic component
FY134_15130	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_15135	COG1129	ABC transporter
FY134_15145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY134_15150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_15155	COG3447	MASE1 domain protein
FY134_15155	COG5001	Diguanylate cyclase
FY134_15155	COG5002	protein histidine kinase activity
FY134_15160	COG3257	ureidoglycine aminohydrolase activity
FY134_15170	COG5001	Diguanylate cyclase
FY134_15175	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY134_15185	COG0747	negative chemotaxis
FY134_15190	COG0601	transmembrane transport
FY134_15195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_15205	COG4608	Belongs to the ABC transporter superfamily
FY134_15220	COG0129	dihydroxy-acid dehydratase activity
FY134_15225	COG1879	ABC-type sugar transport system periplasmic component
FY134_15230	COG1129	ABC transporter
FY134_15235	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_15240	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_15245	COG2186	Transcriptional regulator
FY134_15255	COG0587	DNA-directed DNA polymerase activity
FY134_15285	COG0673	inositol 2-dehydrogenase activity
FY134_15295	COG3842	ATPase activity
FY134_15300	COG0395	ABC-type sugar transport system, permease component
FY134_15305	COG1175	transmembrane transport
FY134_15310	COG1653	transport
FY134_15320	COG0673	inositol 2-dehydrogenase activity
FY134_15335	COG5001	Diguanylate cyclase
FY134_15340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_15350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY134_15355	COG2894	cell division
FY134_15360	COG0850	regulation of cytokinetic process
FY134_15365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_15370	COG2186	Transcriptional regulator
FY134_15375	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_15385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_15390	COG1063	alcohol dehydrogenase
FY134_15395	COG1312	Catalyzes the dehydration of D-mannonate
FY134_15410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_15415	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY134_15415	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_15420	COG4172	Belongs to the ABC transporter superfamily
FY134_15425	COG1921	L-seryl-tRNASec selenium transferase activity
FY134_15440	COG3964	amidohydrolase
FY134_15450	COG0601	transmembrane transport
FY134_15460	COG0438	transferase activity, transferring glycosyl groups
FY134_15495	COG4989	oxidoreductase activity
FY134_15510	COG3842	ATPase activity
FY134_15515	COG1653	transport
FY134_15520	COG1175	transmembrane transport
FY134_15525	COG0395	ABC-type sugar transport system, permease component
FY134_15530	COG1501	Belongs to the glycosyl hydrolase 31 family
FY134_15535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_15540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_15545	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY134_15550	COG0352	thiamine-phosphate diphosphorylase activity
FY134_15555	COG0351	phosphomethylpyrimidine kinase
FY134_15560	COG1522	sequence-specific DNA binding
FY134_15565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY134_15570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_15585	COG2204	response regulator
FY134_15590	COG4191	Histidine kinase
FY134_15595	COG1301	dicarboxylic acid transport
FY134_15605	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_15610	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_15620	COG1473	amidohydrolase
FY134_15640	COG1215	transferase activity, transferring glycosyl groups
FY134_15650	COG2942	2-epimerase
FY134_15685	COG2197	response regulator
FY134_15715	COG3307	-O-antigen
FY134_15720	COG1596	polysaccharide export
FY134_15725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY134_15740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_15745	COG0840	transmembrane signaling receptor activity
FY134_15745	COG2972	Histidine kinase
FY134_15750	COG1376	ErfK ybiS ycfS ynhG family protein
FY134_15750	COG1388	LysM domain
FY134_15760	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_15770	COG2094	Belongs to the DNA glycosylase MPG family
FY134_15780	COG1609	Transcriptional regulator
FY134_15785	COG1653	transport
FY134_15800	COG3842	ATPase activity
FY134_15810	COG0673	inositol 2-dehydrogenase activity
FY134_15815	COG0602	queuosine metabolic process
FY134_15820	COG0720	synthase
FY134_15825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY134_15830	COG0673	inositol 2-dehydrogenase activity
FY134_15845	COG0395	ABC-type sugar transport system, permease component
FY134_15850	COG1175	transmembrane transport
FY134_15870	COG0583	DNA-binding transcription factor activity
FY134_15875	COG0280	phosphate acetyltransferase
FY134_15875	COG0281	malic enzyme
FY134_15890	COG0765	amino acid transport
FY134_15900	COG2079	MmgE PrpD family protein
FY134_15905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_15915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_15930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY134_15935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY134_15940	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY134_15945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY134_15950	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_15955	COG1129	ABC transporter
FY134_15970	COG1473	amidohydrolase
FY134_15990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_15995	COG0601	transmembrane transport
FY134_16000	COG0583	DNA-binding transcription factor activity
FY134_16005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_16010	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY134_16030	COG1595	DNA-templated transcription, initiation
FY134_16035	COG1120	ATPase activity
FY134_16040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_16055	COG2226	methyltransferase
FY134_16065	COG1120	ATPase activity
FY134_16070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_16090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_16100	COG1012	belongs to the aldehyde dehydrogenase family
FY134_16105	COG0473	3-isopropylmalate dehydrogenase activity
FY134_16110	COG1012	belongs to the aldehyde dehydrogenase family
FY134_16115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_16145	COG0601	transmembrane transport
FY134_16150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_16155	COG4172	Belongs to the ABC transporter superfamily
FY134_16160	COG1522	sequence-specific DNA binding
FY134_16165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_16175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_16180	COG1126	abc transporter atp-binding protein
FY134_16190	COG1473	amidohydrolase
FY134_16195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16205	COG1959	2 iron, 2 sulfur cluster binding
FY134_16215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_16220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16240	COG1960	acyl-CoA dehydrogenase activity
FY134_16275	COG0667	Aldo Keto reductase
FY134_16285	COG0583	DNA-binding transcription factor activity
FY134_16290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16305	COG0747	negative chemotaxis
FY134_16310	COG1473	amidohydrolase
FY134_16315	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_16355	COG4608	Belongs to the ABC transporter superfamily
FY134_16360	COG0444	Belongs to the ABC transporter superfamily
FY134_16370	COG0601	transmembrane transport
FY134_16380	COG2186	Transcriptional regulator
FY134_16395	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_16405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_16405	COG3453	Protein conserved in bacteria
FY134_16410	COG0640	Transcriptional regulator
FY134_16420	COG2391	methyltransferase activity
FY134_16425	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY134_16435	COG0022	dehydrogenase e1 component
FY134_16445	COG1960	acyl-CoA dehydrogenase activity
FY134_16450	COG0183	Belongs to the thiolase family
FY134_16460	COG1960	acyl-CoA dehydrogenase activity
FY134_16465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY134_16480	COG1024	Enoyl-CoA hydratase
FY134_16485	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY134_16490	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY134_16495	COG4952	isomerase
FY134_16500	COG3347	Dehydrogenase
FY134_16500	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_16505	COG1349	DNA-binding transcription factor activity
FY134_16515	COG1129	ABC transporter
FY134_16520	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_16530	COG3254	rhamnose metabolic process
FY134_16545	COG2264	protein methyltransferase activity
FY134_16550	COG5001	Diguanylate cyclase
FY134_16565	COG4335	DNA alkylation repair
FY134_16570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY134_16575	COG4208	sulfate ABC transporter
FY134_16585	COG4150	thiosulfate binding
FY134_16590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY134_16605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_16615	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY134_16625	COG1040	competence protein
FY134_16630	COG2226	methyltransferase
FY134_16645	COG0494	nUDIX hydrolase
FY134_16655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY134_16660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY134_16665	COG0653	protein targeting
FY134_16710	COG1312	Catalyzes the dehydration of D-mannonate
FY134_16715	COG0246	Mannitol dehydrogenase
FY134_16735	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_16745	COG1129	ABC transporter
FY134_16775	COG2376	Dihydroxyacetone kinase
FY134_16780	COG3273	potassium ion transport
FY134_16780	COG0471	metal ion transport
FY134_16800	COG0438	transferase activity, transferring glycosyl groups
FY134_16810	COG2244	polysaccharide biosynthetic process
FY134_16830	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY134_16840	COG0489	protein tyrosine kinase activity
FY134_16840	COG3206	protein involved in exopolysaccharide biosynthesis
FY134_16860	COG0438	transferase activity, transferring glycosyl groups
FY134_16865	COG0438	transferase activity, transferring glycosyl groups
FY134_16880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY134_16885	COG2273	Hydrolase Family 16
FY134_16885	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY134_16930	COG1396	sequence-specific DNA binding
FY134_16940	COG1129	ABC transporter
FY134_16945	COG4214	carbohydrate transport
FY134_16950	COG4213	ABC transporter substrate-binding protein
FY134_16965	COG0346	lactoylglutathione lyase activity
FY134_16970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY134_16970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY134_16975	COG4770	biotin carboxylase activity
FY134_16985	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY134_16995	COG0625	glutathione transferase activity
FY134_17000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY134_17005	COG3800	Transcriptional regulator
FY134_17005	COG1396	sequence-specific DNA binding
FY134_17015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY134_17025	COG0300	oxidoreductase activity
FY134_17035	COG2096	Adenosyltransferase
FY134_17045	COG2086	electron transfer activity
FY134_17055	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY134_17060	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY134_17065	COG0165	Argininosuccinate lyase
FY134_17100	COG2884	Cell division ATP-binding protein ftsE
FY134_17120	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY134_17130	COG0287	Prephenate dehydrogenase
FY134_17135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY134_17140	COG2226	methyltransferase
FY134_17145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_17165	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY134_17170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY134_17200	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY134_17205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY134_17215	COG4974	Belongs to the 'phage' integrase family
FY134_17220	COG0825	malonyl-CoA metabolic process
FY134_17225	COG3034	peptidoglycan biosynthetic process
FY134_17230	COG0425	Belongs to the sulfur carrier protein TusA family
FY134_17230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY134_17235	COG0523	cobalamin synthesis protein
FY134_17240	COG1686	Belongs to the peptidase S11 family
FY134_17245	COG1473	amidohydrolase
FY134_17250	COG1959	2 iron, 2 sulfur cluster binding
FY134_17255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FY134_17295	COG2226	methyltransferase
FY134_17330	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY134_17350	COG4774	siderophore transport
FY134_17350	COG1629	transport
FY134_17355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY134_17360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_17365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY134_17370	COG1120	ATPase activity
FY134_17385	COG4953	penicillin-binding protein 1C
FY134_17390	COG2373	Large extracellular alpha-helical protein
FY134_17395	COG2835	tetraacyldisaccharide 4'-kinase activity
FY134_17405	COG3118	belongs to the thioredoxin family
FY134_17420	COG0625	glutathione transferase activity
FY134_17430	COG0482	sulfurtransferase activity
FY134_17445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_17460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY134_17465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_17470	COG0037	tRNA processing
FY134_17480	COG2885	chlorophyll binding
FY134_17485	COG0823	Involved in the tonB-independent uptake of proteins
FY134_17505	COG0824	Thioesterase
FY134_17515	COG0494	nUDIX hydrolase
FY134_17520	COG2318	DinB family
FY134_17530	COG2255	four-way junction helicase activity
FY134_17535	COG0632	four-way junction helicase activity
FY134_17540	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY134_17545	COG0840	transmembrane signaling receptor activity
FY134_17550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_17555	COG0217	transcriptional regulatory protein
FY134_17570	COG1692	metallophosphoesterase
FY134_17580	COG1253	flavin adenine dinucleotide binding
FY134_17615	COG0126	phosphoglycerate kinase activity
FY134_17620	COG3588	fructose-bisphosphate aldolase
FY134_17640	COG0254	rRNA binding
FY134_17645	COG1132	(ABC) transporter
FY134_17665	COG0483	inositol monophosphate 1-phosphatase activity
FY134_17695	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY134_17700	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY134_17705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY134_17710	COG0457	Tetratricopeptide repeat
FY134_17715	COG3750	Belongs to the UPF0335 family
FY134_17735	COG0469	pyruvate kinase activity
FY134_17740	COG3108	Peptidase M15
FY134_17745	COG2204	response regulator
FY134_17750	COG1164	Oligoendopeptidase f
FY134_17755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY134_17765	COG5310	Homospermidine synthase
FY134_17775	COG0737	Belongs to the 5'-nucleotidase family
FY134_17780	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY134_17785	COG0330	HflC and HflK could
FY134_17815	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY134_17820	COG2951	lytic endotransglycosylase activity
FY134_17835	COG2205	protein histidine kinase activity
FY134_17850	COG0070	glutamate synthase
FY134_17850	COG0069	glutamate synthase activity
FY134_17850	COG0067	glutamate synthase
FY134_17860	COG0745	RESPONSE REGULATOR receiver
FY134_17865	COG2205	protein histidine kinase activity
FY134_17870	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY134_17875	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY134_17880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY134_17895	COG0252	asparaginase activity
FY134_17905	COG1027	Aspartate ammonia-lyase
FY134_17910	COG2186	Transcriptional regulator
FY134_17945	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_17950	COG0517	IMP dehydrogenase activity
FY134_17950	COG4175	Glycine betaine
FY134_17955	COG2986	histidine ammonia-lyase
FY134_17960	COG2814	Major facilitator Superfamily
FY134_17975	COG1522	sequence-specific DNA binding
FY134_17980	COG0583	DNA-binding transcription factor activity
FY134_17985	COG0667	Aldo Keto reductase
FY134_17995	COG1335	isochorismatase
FY134_18005	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_18010	COG3254	rhamnose metabolic process
FY134_18025	COG2721	sulfolactate sulfo-lyase activity
FY134_18030	COG1129	ABC transporter
FY134_18040	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_18045	COG1879	ABC-type sugar transport system periplasmic component
FY134_18080	COG0583	DNA-binding transcription factor activity
FY134_18120	COG2307	Protein conserved in bacteria
FY134_18120	COG2308	Evidence 4 Homologs of previously reported genes of
FY134_18135	COG0488	(ABC) transporter
FY134_18140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_18145	COG1304	FMN binding
FY134_18155	COG1846	Transcriptional regulator
FY134_18165	COG1070	Carbohydrate kinase
FY134_18170	COG1830	Aldolase
FY134_18175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY134_18180	COG0667	Aldo Keto reductase
FY134_18190	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_18195	COG1129	ABC transporter
FY134_18200	COG1879	ABC-type sugar transport system periplasmic component
FY134_18340	COG0071	Belongs to the small heat shock protein (HSP20) family
FY134_18355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY134_18370	COG0395	ABC-type sugar transport system, permease component
FY134_18385	COG3842	ATPase activity
FY134_18400	COG1648	precorrin-2 dehydrogenase activity
FY134_18400	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY134_18405	COG0243	molybdopterin cofactor binding
FY134_18415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY134_18420	COG1116	anion transmembrane transporter activity
FY134_18425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_18430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_18440	COG3707	response regulator
FY134_18445	COG1802	Transcriptional regulator
FY134_18450	COG1914	H( )-stimulated, divalent metal cation uptake system
FY134_18455	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY134_18460	COG4336	lyase activity
FY134_18465	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY134_18470	COG4770	biotin carboxylase activity
FY134_18475	COG0366	Alpha amylase catalytic
FY134_18485	COG4771	TonB-dependent receptor
FY134_18510	COG1414	Transcriptional regulator
FY134_18515	COG1475	DNA binding
FY134_18520	COG1192	Involved in chromosome partitioning
FY134_18550	COG0596	Alpha beta hydrolase
FY134_18555	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY134_18565	COG2986	histidine ammonia-lyase
FY134_18570	COG1228	amidohydrolase
FY134_18575	COG0402	S-adenosylhomocysteine deaminase activity
FY134_18630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_18640	COG2423	ornithine cyclodeaminase activity
FY134_18655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_18660	COG3938	Belongs to the proline racemase family
FY134_18665	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_18675	COG4175	Glycine betaine
FY134_18675	COG3448	diguanylate cyclase activity
FY134_18685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_18690	COG1012	belongs to the aldehyde dehydrogenase family
FY134_18695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_18725	COG0673	inositol 2-dehydrogenase activity
FY134_18730	COG0673	inositol 2-dehydrogenase activity
FY134_18740	COG1175	transmembrane transport
FY134_18745	COG0395	ABC-type sugar transport system, permease component
FY134_18750	COG3842	ATPase activity
FY134_18760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_18765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY134_18790	COG0583	DNA-binding transcription factor activity
FY134_18795	COG0346	lactoylglutathione lyase activity
FY134_18810	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY134_18825	COG2814	Major facilitator Superfamily
FY134_18840	COG0583	DNA-binding transcription factor activity
FY134_18845	COG0477	Major facilitator Superfamily
FY134_18895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY134_18905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY134_18910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_18915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY134_18945	COG0010	Belongs to the arginase family
FY134_18955	COG0697	spore germination
FY134_18960	COG0673	inositol 2-dehydrogenase activity
FY134_18980	COG0477	Major facilitator Superfamily
FY134_18985	COG0642	Histidine kinase
FY134_18995	COG2194	sulfuric ester hydrolase activity
FY134_19005	COG0583	DNA-binding transcription factor activity
FY134_19010	COG4774	siderophore transport
FY134_19025	COG1120	ATPase activity
FY134_19035	COG3474	cytochrome
FY134_19040	COG2137	regulation of response to DNA damage stimulus
FY134_19045	COG3386	PFAM SMP-30 Gluconolaconase
FY134_19055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_19060	COG1129	ABC transporter
FY134_19065	COG1879	ABC-type sugar transport system periplasmic component
FY134_19070	COG4585	Histidine kinase
FY134_19075	COG2197	response regulator
FY134_19085	COG2133	pyrroloquinoline quinone binding
FY134_19095	COG0500	methyltransferase
FY134_19100	COG0564	pseudouridine synthase activity
FY134_19115	COG0517	IMP dehydrogenase activity
FY134_19115	COG4175	Glycine betaine
FY134_19120	COG4176	ABC-type proline glycine betaine transport system permease component
FY134_19130	COG4191	Histidine kinase
FY134_19130	COG0784	Response regulator, receiver
FY134_19135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_19140	COG3206	protein involved in exopolysaccharide biosynthesis
FY134_19140	COG0489	protein tyrosine kinase activity
FY134_19145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY134_19150	COG1215	transferase activity, transferring glycosyl groups
FY134_19155	COG1215	transferase activity, transferring glycosyl groups
FY134_19160	COG1215	transferase activity, transferring glycosyl groups
FY134_19165	COG0438	transferase activity, transferring glycosyl groups
FY134_19170	COG2273	Hydrolase Family 16
FY134_19175	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY134_19180	COG2244	polysaccharide biosynthetic process
FY134_19185	COG0463	Glycosyl transferase, family 2
FY134_19190	COG2327	Polysaccharide pyruvyl transferase
FY134_19195	COG1215	transferase activity, transferring glycosyl groups
FY134_19215	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY134_19220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_19235	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_19235	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_19260	COG0033	Phosphoglucomutase
FY134_19265	COG0297	glycogen (starch) synthase activity
FY134_19270	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY134_19275	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY134_19280	COG0058	SHG alpha-glucan phosphorylase activity
FY134_19290	COG1794	racemase activity, acting on amino acids and derivatives
FY134_19295	COG1522	sequence-specific DNA binding
FY134_19305	COG2084	Dehydrogenase
FY134_19310	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_19315	COG1063	alcohol dehydrogenase
FY134_19325	COG4988	ABC transporter
FY134_19330	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY134_19340	COG1294	oxidase, subunit
FY134_19370	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY134_19375	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY134_19405	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY134_19410	COG0539	negative regulation of cytoplasmic translation
FY134_19440	COG4221	oxidoreductase activity
FY134_19445	COG0006	proline dipeptidase activity
FY134_19450	COG0747	negative chemotaxis
FY134_19455	COG0601	transmembrane transport
FY134_19460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_19465	COG0444	Belongs to the ABC transporter superfamily
FY134_19470	COG4608	Belongs to the ABC transporter superfamily
FY134_19485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_19510	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY134_19530	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY134_19535	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_19555	COG4993	Dehydrogenase
FY134_19560	COG3685	Protein conserved in bacteria
FY134_19590	COG0693	protein deglycase activity
FY134_19610	COG0189	ligase activity
FY134_19615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_19620	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY134_19630	COG0583	DNA-binding transcription factor activity
FY134_19635	COG1012	belongs to the aldehyde dehydrogenase family
FY134_19640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_19645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_19650	COG1116	anion transmembrane transporter activity
FY134_19660	COG1522	sequence-specific DNA binding
FY134_19675	COG0784	Response regulator, receiver
FY134_19685	COG3920	Histidine kinase
FY134_19695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY134_19710	COG0019	diaminopimelate decarboxylase activity
FY134_19720	COG0513	Belongs to the DEAD box helicase family
FY134_19725	COG0527	aspartate kinase activity
FY134_19735	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY134_19740	COG2890	protein-(glutamine-N5) methyltransferase activity
FY134_19750	COG0542	response to heat
FY134_19755	COG1196	nuclear chromosome segregation
FY134_19755	COG0741	lytic transglycosylase activity
FY134_19755	COG0739	heme binding
FY134_19795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_19805	COG2186	Transcriptional regulator
FY134_19810	COG0747	negative chemotaxis
FY134_19815	COG0601	transmembrane transport
FY134_19820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_19825	COG4172	Belongs to the ABC transporter superfamily
FY134_19830	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_19865	COG1881	PFAM PEBP family protein
FY134_19890	COG1278	Cold shock
FY134_19900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY134_19920	COG0300	oxidoreductase activity
FY134_19930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_19930	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_19935	COG4311	Sarcosine oxidase, delta subunit
FY134_19940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_19945	COG4977	sequence-specific DNA binding
FY134_19955	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY134_19960	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY134_19965	COG0069	glutamate synthase activity
FY134_19970	COG0174	glutamine synthetase
FY134_19990	COG0765	amino acid transport
FY134_19995	COG1126	abc transporter atp-binding protein
FY134_20000	COG1454	alcohol dehydrogenase
FY134_20010	COG2267	carboxylic ester hydrolase activity
FY134_20020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_20025	COG1012	belongs to the aldehyde dehydrogenase family
FY134_20045	COG1177	transmembrane transport
FY134_20060	COG3842	ATPase activity
FY134_20065	COG0395	ABC-type sugar transport system, permease component
FY134_20070	COG1175	transmembrane transport
FY134_20080	COG3976	FMN-binding domain protein
FY134_20080	COG1053	succinate dehydrogenase
FY134_20085	COG1609	Transcriptional regulator
FY134_20095	COG4172	Belongs to the ABC transporter superfamily
FY134_20100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_20105	COG0601	transmembrane transport
FY134_20115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_20130	COG2828	Protein conserved in bacteria
FY134_20135	COG0583	DNA-binding transcription factor activity
FY134_20145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_20155	COG1280	lysine exporter protein (LysE YggA)
FY134_20165	COG0494	nUDIX hydrolase
FY134_20170	COG0583	DNA-binding transcription factor activity
FY134_20180	COG0511	ligase activity, forming carbon-carbon bonds
FY134_20185	COG0439	Biotin carboxylase
FY134_20200	COG1984	allophanate hydrolase subunit 2
FY134_20205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY134_20210	COG0436	Aminotransferase
FY134_20220	COG4221	oxidoreductase activity
FY134_20225	COG0765	amino acid transport
FY134_20230	COG0765	amino acid transport
FY134_20235	COG1126	abc transporter atp-binding protein
FY134_20240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_20245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY134_20260	COG0583	DNA-binding transcription factor activity
FY134_20270	COG0583	DNA-binding transcription factor activity
FY134_20275	COG2814	Major facilitator Superfamily
FY134_20290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_20300	COG2207	Transcriptional regulator
FY134_20305	COG0668	transmembrane transport
FY134_20315	COG4566	intracellular signal transduction
FY134_20335	COG0668	transmembrane transport
FY134_20340	COG4191	Histidine kinase
FY134_20345	COG0784	Response regulator, receiver
FY134_20345	COG5002	protein histidine kinase activity
FY134_20345	COG2205	protein histidine kinase activity
FY134_20350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY134_20365	COG0047	phosphoribosylformylglycinamidine synthase activity
FY134_20380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_20380	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY134_20390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY134_20405	COG1309	transcriptional regulator
FY134_20410	COG1063	alcohol dehydrogenase
FY134_20420	COG1879	ABC-type sugar transport system periplasmic component
FY134_20430	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_20580	COG5001	Diguanylate cyclase
FY134_20590	COG1253	flavin adenine dinucleotide binding
FY134_20605	COG3842	ATPase activity
FY134_20610	COG0395	ABC-type sugar transport system, permease component
FY134_20615	COG1175	transmembrane transport
FY134_20620	COG1653	transport
FY134_20630	COG0673	inositol 2-dehydrogenase activity
FY134_20635	COG1609	Transcriptional regulator
FY134_20650	COG0583	DNA-binding transcription factor activity
FY134_20660	COG1879	ABC-type sugar transport system periplasmic component
FY134_20665	COG1129	ABC transporter
FY134_20670	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_20675	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_20680	COG1609	Transcriptional regulator
FY134_20690	COG0673	inositol 2-dehydrogenase activity
FY134_20715	COG3189	MarR family transcriptional regulator
FY134_20730	COG1960	acyl-CoA dehydrogenase activity
FY134_20735	COG0583	DNA-binding transcription factor activity
FY134_20740	COG1609	Transcriptional regulator
FY134_20750	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_20760	COG3842	ATPase activity
FY134_20770	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY134_20780	COG1473	amidohydrolase
FY134_20795	COG0747	negative chemotaxis
FY134_20800	COG0601	transmembrane transport
FY134_20805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_20810	COG0444	Belongs to the ABC transporter superfamily
FY134_20815	COG4608	Belongs to the ABC transporter superfamily
FY134_20820	COG0583	DNA-binding transcription factor activity
FY134_20825	COG0747	negative chemotaxis
FY134_20835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_20840	COG0154	amidase activity
FY134_20845	COG0693	protein deglycase activity
FY134_20855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_20860	COG0601	transmembrane transport
FY134_20870	COG1473	amidohydrolase
FY134_20875	COG4172	Belongs to the ABC transporter superfamily
FY134_20880	COG2390	Transcriptional regulator
FY134_20890	COG1175	transmembrane transport
FY134_20895	COG0395	ABC-type sugar transport system, permease component
FY134_20910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY134_20915	COG1069	ribulokinase activity
FY134_20920	COG1737	Transcriptional regulator
FY134_20940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY134_20950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY134_20955	COG1414	Transcriptional regulator
FY134_20960	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_20970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY134_20975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY134_20980	COG1121	(ABC) transporter
FY134_20985	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY134_20995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY134_21000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY134_21005	COG0471	metal ion transport
FY134_21005	COG3273	potassium ion transport
FY134_21010	COG1253	flavin adenine dinucleotide binding
FY134_21015	COG1309	transcriptional regulator
FY134_21030	COG1609	Transcriptional regulator
FY134_21035	COG1070	Carbohydrate kinase
FY134_21040	COG2115	Belongs to the xylose isomerase family
FY134_21050	COG0778	Nitroreductase
FY134_21055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY134_21060	COG2011	ABC-type metal ion transport system permease component
FY134_21070	COG3300	MHYT domain
FY134_21070	COG5001	Diguanylate cyclase
FY134_21075	COG1054	Belongs to the UPF0176 family
FY134_21085	COG2954	triphosphatase activity
FY134_21090	COG0800	Aldolase
FY134_21110	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY134_21130	COG2814	Major facilitator Superfamily
FY134_21140	COG0523	cobalamin synthesis protein
FY134_21150	COG1846	Transcriptional regulator
FY134_21155	COG1609	Transcriptional regulator
FY134_21165	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_21170	COG0673	inositol 2-dehydrogenase activity
FY134_21175	COG3718	enzyme involved in inositol metabolism
FY134_21185	COG3962	Belongs to the TPP enzyme family
FY134_21190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_21220	COG0683	leucine binding
FY134_21235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_21245	COG0747	negative chemotaxis
FY134_21250	COG4172	Belongs to the ABC transporter superfamily
FY134_21260	COG3185	4-Hydroxyphenylpyruvate dioxygenase
FY134_21260	COG1082	Xylose isomerase domain protein TIM barrel
FY134_21270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY134_21275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_21280	COG1126	abc transporter atp-binding protein
FY134_21285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_21290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_21295	COG0765	amino acid transport
FY134_21300	COG0765	amino acid transport
FY134_21310	COG3485	protocatechuate 3,4-dioxygenase
FY134_21315	COG3485	protocatechuate 3,4-dioxygenase
FY134_21320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY134_21330	COG0583	DNA-binding transcription factor activity
FY134_21345	COG1414	Transcriptional regulator
FY134_21355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY134_21360	COG0183	Belongs to the thiolase family
FY134_21365	COG1609	Transcriptional regulator
FY134_21380	COG1082	Xylose isomerase domain protein TIM barrel
FY134_21385	COG0673	inositol 2-dehydrogenase activity
FY134_21395	COG1609	Transcriptional regulator
FY134_21400	COG0395	ABC-type sugar transport system, permease component
FY134_21405	COG1175	transmembrane transport
FY134_21410	COG3842	ATPase activity
FY134_21420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY134_21450	COG3842	ATPase activity
FY134_21455	COG4149	molybdate abc transporter
FY134_21465	COG0584	glycerophosphoryl diester phosphodiesterase
FY134_21470	COG0483	inositol monophosphate 1-phosphatase activity
FY134_21475	COG0300	oxidoreductase activity
FY134_21485	COG1940	carbohydrate kinase activity
FY134_21485	COG1846	Transcriptional regulator
FY134_21495	COG3842	ATPase activity
FY134_21515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY134_21550	COG0385	Bile acid
FY134_21555	COG0667	Aldo Keto reductase
FY134_21560	COG0583	DNA-binding transcription factor activity
FY134_21570	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY134_21580	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_21590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_21605	COG1132	(ABC) transporter
FY134_21630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_21645	COG0463	Glycosyl transferase, family 2
FY134_21665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FY134_21675	COG4106	trans-aconitate 2-methyltransferase activity
FY134_21680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY134_21685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY134_21695	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY134_21700	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY134_21705	COG1088	dTDP-glucose 4,6-dehydratase activity
FY134_21710	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY134_21725	COG0444	Belongs to the ABC transporter superfamily
FY134_21730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_21735	COG0601	transmembrane transport
FY134_21740	COG2186	Transcriptional regulator
FY134_21745	COG1312	Catalyzes the dehydration of D-mannonate
FY134_21750	COG0747	negative chemotaxis
FY134_21760	COG3300	MHYT domain
FY134_21760	COG5001	Diguanylate cyclase
FY134_21765	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_21775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY134_21785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY134_21790	COG0306	phosphate transporter
FY134_21795	COG1392	Phosphate transport regulator
FY134_21815	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY134_21825	COG1012	belongs to the aldehyde dehydrogenase family
FY134_21840	COG3119	arylsulfatase activity
FY134_21845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_21850	COG3842	ATPase activity
FY134_21855	COG0165	Argininosuccinate lyase
FY134_21860	COG0395	ABC-type sugar transport system, permease component
FY134_21865	COG1175	transmembrane transport
FY134_21870	COG2182	Extracellular solute-binding protein
FY134_21875	COG1940	carbohydrate kinase activity
FY134_21900	COG1486	melibiose metabolic process
FY134_21905	COG0747	negative chemotaxis
FY134_21910	COG0601	transmembrane transport
FY134_21915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_21920	COG4172	Belongs to the ABC transporter superfamily
FY134_21925	COG1486	melibiose metabolic process
FY134_21930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_21935	COG1129	ABC transporter
FY134_21935	COG0842	Transport permease protein
FY134_21940	COG0842	Transport permease protein
FY134_21955	COG0784	Response regulator, receiver
FY134_21960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY134_21970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_21975	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY134_21990	COG0765	amino acid transport
FY134_22000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_22010	COG3938	Belongs to the proline racemase family
FY134_22025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_22030	COG0765	amino acid transport
FY134_22035	COG0765	amino acid transport
FY134_22045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY134_22060	COG0402	S-adenosylhomocysteine deaminase activity
FY134_22070	COG0601	transmembrane transport
FY134_22075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_22085	COG0402	S-adenosylhomocysteine deaminase activity
FY134_22090	COG0444	Belongs to the ABC transporter superfamily
FY134_22095	COG4608	Belongs to the ABC transporter superfamily
FY134_22100	COG1802	Transcriptional regulator
FY134_22105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY134_22130	COG3383	formate dehydrogenase (NAD+) activity
FY134_22140	COG2223	nitrite transmembrane transporter activity
FY134_22170	COG3237	CsbD-like
FY134_22175	COG2197	response regulator
FY134_22180	COG2186	Transcriptional regulator
FY134_22185	COG0747	negative chemotaxis
FY134_22190	COG0601	transmembrane transport
FY134_22195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_22200	COG0405	Gamma-glutamyltransferase
FY134_22210	COG0483	inositol monophosphate 1-phosphatase activity
FY134_22220	COG3842	ATPase activity
FY134_22245	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY134_22250	COG3181	Tripartite tricarboxylate transporter family receptor
FY134_22255	COG5265	(ABC) transporter
FY134_22260	COG0488	(ABC) transporter
FY134_22285	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY134_22290	COG0840	transmembrane signaling receptor activity
FY134_22300	COG0110	maltose O-acetyltransferase activity
FY134_22310	COG1063	alcohol dehydrogenase
FY134_22315	COG3284	Transcriptional regulator
FY134_22335	COG1129	ABC transporter
FY134_22340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_22345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_22360	COG1082	Xylose isomerase domain protein TIM barrel
FY134_22370	COG1126	abc transporter atp-binding protein
FY134_22375	COG0765	amino acid transport
FY134_22380	COG0765	amino acid transport
FY134_22385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_22390	COG3608	succinylglutamate desuccinylase aspartoacylase
FY134_22395	COG0006	proline dipeptidase activity
FY134_22400	COG2423	ornithine cyclodeaminase activity
FY134_22405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY134_22410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY134_22415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY134_22420	COG1012	belongs to the aldehyde dehydrogenase family
FY134_22425	COG1522	sequence-specific DNA binding
FY134_22430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY134_22460	COG2140	Oxalate decarboxylase
FY134_22475	COG4566	intracellular signal transduction
FY134_22485	COG0243	molybdopterin cofactor binding
FY134_22490	COG0783	Belongs to the Dps family
FY134_22510	COG0596	Alpha beta hydrolase
FY134_22520	COG1764	response to oxidative stress
FY134_22535	COG0596	Alpha beta hydrolase
FY134_22565	COG4191	Histidine kinase
FY134_22565	COG0784	Response regulator, receiver
FY134_22575	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_22580	COG1840	ABC-type Fe3 transport system, periplasmic component
FY134_22590	COG3842	ATPase activity
FY134_22595	COG0483	inositol monophosphate 1-phosphatase activity
FY134_22610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_22635	COG2197	response regulator
FY134_22640	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY134_22645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY134_22655	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY134_22660	COG4310	Domain of unknown function (DUF2172)
FY134_22665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY134_22670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY134_22675	COG2197	response regulator
FY134_22680	COG4566	intracellular signal transduction
FY134_22710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY134_22730	COG0438	transferase activity, transferring glycosyl groups
FY134_22745	COG1522	sequence-specific DNA binding
FY134_22765	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_22780	COG1414	Transcriptional regulator
FY134_22790	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_22815	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY134_22845	COG1349	DNA-binding transcription factor activity
FY134_22850	COG1879	ABC-type sugar transport system periplasmic component
FY134_22855	COG1129	ABC transporter
FY134_22860	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_22865	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_22885	COG1012	belongs to the aldehyde dehydrogenase family
FY134_22890	COG1280	lysine exporter protein (LysE YggA)
FY134_22905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY134_22955	COG4529	Protein conserved in bacteria
FY134_23005	COG3422	double-strand break repair
FY134_23020	COG1192	Involved in chromosome partitioning
FY134_23025	COG1475	DNA binding
FY134_23030	COG0640	Transcriptional regulator
FY134_23045	COG1126	abc transporter atp-binding protein
FY134_23050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_23055	COG1609	Transcriptional regulator
FY134_23075	COG1733	regulation of RNA biosynthetic process
FY134_23190	COG4691	Plasmid stability protein
FY134_23195	COG1487	ribonuclease activity
FY134_23210	COG0534	Mate efflux family protein
FY134_23215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY134_23230	COG0596	Alpha beta hydrolase
FY134_23275	COG3920	Histidine kinase
FY134_23290	COG0784	Response regulator, receiver
FY134_23310	COG4095	Psort location CytoplasmicMembrane, score
FY134_23340	COG0753	catalase activity
FY134_23345	COG3685	Protein conserved in bacteria
FY134_23380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY134_23385	COG0297	glycogen (starch) synthase activity
FY134_23465	COG1609	Transcriptional regulator
FY134_23490	COG0673	inositol 2-dehydrogenase activity
FY134_23500	COG4608	Belongs to the ABC transporter superfamily
FY134_23510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_23515	COG0601	transmembrane transport
FY134_23520	COG0747	negative chemotaxis
FY134_23525	COG1802	Transcriptional regulator
FY134_23535	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_23625	COG1175	transmembrane transport
FY134_23630	COG0395	ABC-type sugar transport system, permease component
FY134_23640	COG3842	ATPase activity
FY134_23645	COG1737	Transcriptional regulator
FY134_23650	COG1846	Transcriptional regulator
FY134_23665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_23675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_23680	COG0601	transmembrane transport
FY134_23685	COG0747	negative chemotaxis
FY134_23695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY134_23700	COG1454	alcohol dehydrogenase
FY134_23710	COG3395	kinase activity
FY134_23720	COG2020	methyltransferase activity
FY134_23730	COG0492	ferredoxin-NADP+ reductase activity
FY134_23730	COG3118	belongs to the thioredoxin family
FY134_23735	COG1309	transcriptional regulator
FY134_23760	COG3177	Filamentation induced by cAMP protein fic
FY134_23765	COG1309	transcriptional regulator
FY134_23790	COG0372	Belongs to the citrate synthase family
FY134_23845	COG4423	Transcription factor
FY134_23860	COG0840	transmembrane signaling receptor activity
FY134_23875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY134_23880	COG1070	Carbohydrate kinase
FY134_23890	COG1175	transmembrane transport
FY134_23900	COG3842	ATPase activity
FY134_23910	COG2390	Transcriptional regulator
FY134_23980	COG0714	Associated with various cellular activities
FY134_23985	COG3256	nitric oxide reductase
FY134_24000	COG1845	cytochrome c oxidase, subunit III
FY134_24010	COG0163	prenyltransferase activity
FY134_24015	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY134_24020	COG3189	MarR family transcriptional regulator
FY134_24030	COG0826	peptidase U32
FY134_24055	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY134_24065	COG4459	periplasmic nitrate reductase
FY134_24080	COG0243	molybdopterin cofactor binding
FY134_24090	COG3005	denitrification pathway
FY134_24130	COG2268	Band 7 protein
FY134_24150	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_24155	COG0583	DNA-binding transcription factor activity
FY134_24180	COG0583	DNA-binding transcription factor activity
FY134_24195	COG1177	transmembrane transport
FY134_24200	COG3842	ATPase activity
FY134_24205	COG2072	flavoprotein involved in K transport
FY134_24225	COG0534	Mate efflux family protein
FY134_24250	COG1609	Transcriptional regulator
FY134_24255	COG1082	Xylose isomerase domain protein TIM barrel
FY134_24260	COG0673	inositol 2-dehydrogenase activity
FY134_24265	COG1082	Xylose isomerase domain protein TIM barrel
FY134_24275	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_24295	COG2972	Histidine kinase
FY134_24295	COG0840	transmembrane signaling receptor activity
FY134_24310	COG4221	oxidoreductase activity
FY134_24315	COG1902	pentaerythritol trinitrate reductase activity
FY134_24320	COG0596	Alpha beta hydrolase
FY134_24330	COG3831	ATPase activity
FY134_24335	COG0071	Belongs to the small heat shock protein (HSP20) family
FY134_24350	COG0577	efflux transmembrane transporter activity
FY134_24365	COG3734	2-keto-3-deoxy-galactonokinase
FY134_24370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_24375	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_24385	COG1175	transmembrane transport
FY134_24390	COG0395	ABC-type sugar transport system, permease component
FY134_24395	COG3842	ATPase activity
FY134_24400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY134_24405	COG1414	Transcriptional regulator
FY134_24410	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_24415	COG3158	transport of potassium into the cell
FY134_24425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY134_24440	COG2826	transposase and inactivated derivatives, IS30 family
FY134_24460	COG0504	CTP synthase activity
FY134_24465	COG0006	proline dipeptidase activity
FY134_24470	COG4948	Mandelate Racemase Muconate Lactonizing
FY134_24475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY134_24485	COG0765	amino acid transport
FY134_24490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_24535	COG0753	catalase activity
FY134_24550	COG3685	Protein conserved in bacteria
FY134_24560	COG1309	transcriptional regulator
FY134_24565	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY134_24570	COG2080	2 iron, 2 sulfur cluster binding
FY134_24575	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY134_24580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY134_24585	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY134_24630	COG0784	Response regulator, receiver
FY134_24630	COG4191	Histidine kinase
FY134_24635	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
FY134_24650	COG1278	Cold shock
FY134_24715	COG3920	Histidine kinase
FY134_24760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY134_24770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY134_24780	COG1566	PFAM secretion protein HlyD family protein
FY134_24800	COG2207	Transcriptional regulator
FY134_24825	COG1192	Involved in chromosome partitioning
FY134_24830	COG1475	DNA binding
FY134_24835	COG0640	Transcriptional regulator
FY134_24840	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY134_24885	COG0583	DNA-binding transcription factor activity
FY134_24895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY134_24900	COG1116	anion transmembrane transporter activity
FY134_24905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY134_24915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_24920	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_24950	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_24955	COG1129	ABC transporter
FY134_24980	COG4172	Belongs to the ABC transporter superfamily
FY134_24985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_24990	COG0601	transmembrane transport
FY134_25000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_25005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY134_25010	COG0583	DNA-binding transcription factor activity
FY134_25020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY134_25035	COG1132	(ABC) transporter
FY134_25040	COG4172	Belongs to the ABC transporter superfamily
FY134_25045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_25065	COG1082	Xylose isomerase domain protein TIM barrel
FY134_25070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY134_25075	COG0019	diaminopimelate decarboxylase activity
FY134_25085	COG1475	DNA binding
FY134_25095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY134_25185	COG1475	DNA binding
FY134_25210	COG2824	Alkylphosphonate utilization operon protein PhnA
FY134_25260	COG5489	Protein of unknown function (DUF736)
FY134_25345	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY134_25360	COG0747	negative chemotaxis
FY134_25365	COG0444	Belongs to the ABC transporter superfamily
FY134_25380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_25385	COG0584	glycerophosphoryl diester phosphodiesterase
FY134_25390	COG0483	inositol monophosphate 1-phosphatase activity
FY134_25455	COG3161	chorismate lyase activity
FY134_25605	COG3436	PFAM IS66 Orf2 family protein
FY134_25685	COG2222	sugar isomerase
FY134_25695	COG0006	proline dipeptidase activity
FY134_25715	COG1177	transmembrane transport
FY134_25720	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY134_25725	COG3842	ATPase activity
FY134_25755	COG3842	ATPase activity
FY134_25760	COG0006	proline dipeptidase activity
FY134_25780	COG0300	oxidoreductase activity
FY134_25785	COG0129	dihydroxy-acid dehydratase activity
FY134_25790	COG0667	Aldo Keto reductase
FY134_25800	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_25810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_25815	COG0601	transmembrane transport
FY134_25820	COG4172	Belongs to the ABC transporter superfamily
FY134_25830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY134_25865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY134_25900	COG3701	Conjugal transfer protein
FY134_25905	COG3846	protein secretion by the type IV secretion system
FY134_25915	COG5314	conjugation
FY134_25920	COG3451	type IV secretory pathway VirB4
FY134_25935	COG4962	Type ii secretion system protein e
FY134_25945	COG1192	Involved in chromosome partitioning
FY134_25950	COG1475	DNA binding
FY134_25955	COG0640	Transcriptional regulator
FY134_26020	COG3621	Patatin-like phospholipase
FY134_26045	COG1802	Transcriptional regulator
FY134_26050	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY134_26055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_26060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY134_26070	COG3971	2-oxopent-4-enoate hydratase activity
FY134_26075	COG3485	protocatechuate 3,4-dioxygenase
FY134_26080	COG0683	leucine binding
FY134_26105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_26115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY134_26120	COG3959	Transketolase, thiamine diphosphate binding domain
FY134_26125	COG3958	Transketolase
FY134_26135	COG1063	alcohol dehydrogenase
FY134_26140	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY134_26150	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_26165	COG1802	Transcriptional regulator
FY134_26175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY134_26190	COG2186	Transcriptional regulator
FY134_26200	COG1126	abc transporter atp-binding protein
FY134_26210	COG0765	amino acid transport
FY134_26215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY134_26230	COG0436	Aminotransferase
FY134_26235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_26245	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_26255	COG1609	Transcriptional regulator
FY134_26260	COG0673	inositol 2-dehydrogenase activity
FY134_26270	COG0673	inositol 2-dehydrogenase activity
FY134_26285	COG3718	enzyme involved in inositol metabolism
FY134_26295	COG3962	Belongs to the TPP enzyme family
FY134_26300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY134_26310	COG0673	inositol 2-dehydrogenase activity
FY134_26315	COG1082	Xylose isomerase domain protein TIM barrel
FY134_26325	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY134_26330	COG1129	ABC transporter
FY134_26340	COG1609	Transcriptional regulator
FY134_26345	COG1309	transcriptional regulator
FY134_26350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY134_26380	COG0626	cystathionine gamma-synthase activity
FY134_26405	COG4598	ABC transporter
FY134_26410	COG0583	DNA-binding transcription factor activity
FY134_26420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY134_26490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY134_26495	COG1012	belongs to the aldehyde dehydrogenase family
FY134_26515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY134_26520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY134_26545	COG1126	abc transporter atp-binding protein
FY134_26565	COG1960	acyl-CoA dehydrogenase activity
FY134_26580	COG1309	transcriptional regulator
FY134_26600	COG1137	ATPase activity
FY134_26620	COG3485	protocatechuate 3,4-dioxygenase
FY134_26635	COG1309	transcriptional regulator
FY134_26655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY134_26680	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY134_26715	COG0583	DNA-binding transcription factor activity
FY134_26775	COG0587	DNA-directed DNA polymerase activity
FY134_26795	COG5489	Protein of unknown function (DUF736)
FY134_26800	COG4974	Belongs to the 'phage' integrase family
FY134_26815	COG0494	nUDIX hydrolase
FY134_26830	COG0776	regulation of translation
FY134_26835	COG3831	ATPase activity
FY134_26900	COG0395	ABC-type sugar transport system, permease component
FY134_26905	COG1175	transmembrane transport
FY134_26940	COG0640	Transcriptional regulator
FY134_26945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY134_26950	COG1335	isochorismatase
FY134_26960	COG3836	Belongs to the HpcH HpaI aldolase family
FY134_26965	COG1028	Short-chain dehydrogenase reductase Sdr
FY134_26985	COG0436	Aminotransferase
FY134_27000	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY134_27025	COG1012	belongs to the aldehyde dehydrogenase family
FY134_27030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FY134_27070	COG3701	Conjugal transfer protein
FY134_27075	COG3846	protein secretion by the type IV secretion system
FY134_27085	COG5314	conjugation
FY134_27090	COG3451	type IV secretory pathway VirB4
FY134_27105	COG4962	Type ii secretion system protein e
FY134_27115	COG1192	Involved in chromosome partitioning
FY134_27120	COG1475	DNA binding
FY134_27125	COG0640	Transcriptional regulator
FY134_27135	COG1473	amidohydrolase
FY134_27200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY134_27245	COG3620	sequence-specific DNA binding
FY134_27250	COG3550	peptidyl-serine autophosphorylation
FY134_27290	COG1858	cytochrome C peroxidase
FY134_27300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY134_27305	COG0583	DNA-binding transcription factor activity
FY134_27315	COG1733	regulation of RNA biosynthetic process
FY134_27335	COG0741	lytic transglycosylase activity
FY134_27335	COG1196	nuclear chromosome segregation
FY134_27335	COG0739	heme binding
FY134_27350	COG3451	type IV secretory pathway VirB4
FY134_27380	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY134_27395	COG1192	Involved in chromosome partitioning
FY134_27400	COG3505	Type IV secretory pathway VirD4
FY134_27505	COG3436	PFAM IS66 Orf2 family protein
FY134_27515	COG1940	carbohydrate kinase activity
FY134_27520	COG1653	transport
FY134_27525	COG1175	transmembrane transport
FY134_27530	COG0395	ABC-type sugar transport system, permease component
FY134_27545	COG3842	ATPase activity
FY134_27550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY134_27570	COG3831	ATPase activity
FY134_27660	COG3701	Conjugal transfer protein
FY134_27665	COG3846	protein secretion by the type IV secretion system
FY134_27675	COG5314	conjugation
FY134_27680	COG3451	type IV secretory pathway VirB4
FY134_27695	COG4962	Type ii secretion system protein e