locus-tag	class	description
Arad_0001	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Arad_0002	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Arad_0003	COG0237	dephospho-CoA kinase activity
Arad_0006	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Arad_0011	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Arad_0014	COG0187	DNA topoisomerase II activity
Arad_0024	COG0135	phosphoribosylanthranilate isomerase activity
Arad_0026	COG0133	tryptophan synthase activity
Arad_0028	COG0159	tryptophan synthase activity
Arad_0030	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Arad_0034	COG1074	ATP-dependent DNA helicase activity
Arad_0036	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Arad_0037	COG3178	'Phosphotransferase
Arad_0038	COG2205	protein histidine kinase activity
Arad_0039	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Arad_0041	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Arad_0042	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Arad_0042	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Arad_0045	COG0642	Histidine kinase
Arad_0046	COG0745	RESPONSE REGULATOR receiver
Arad_0047	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Arad_0050	COG3145	DNA-N1-methyladenine dioxygenase activity
Arad_0052	COG1072	(Pantothenic acid kinase))
Arad_0053	COG0140	phosphoribosyl-ATP diphosphatase activity
Arad_0055	COG0107	imidazoleglycerol-phosphate synthase activity
Arad_0056	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Arad_0057	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Arad_0060	COG0131	Imidazoleglycerol-phosphate dehydratase
Arad_0061	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Arad_0063	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Arad_0071	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Arad_0074	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Arad_0076	COG1643	Atp-dependent helicase
Arad_0078	COG2423	ornithine cyclodeaminase activity
Arad_0097	COG0517	IMP dehydrogenase activity
Arad_0102	COG1012	belongs to the aldehyde dehydrogenase family
Arad_0103	COG0673	inositol 2-dehydrogenase activity
Arad_0105	COG3962	Belongs to the TPP enzyme family
Arad_0107	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_0109	COG0673	inositol 2-dehydrogenase activity
Arad_0113	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_0116	COG0673	inositol 2-dehydrogenase activity
Arad_0117	COG1082	Xylose isomerase domain protein TIM barrel
Arad_0126	COG0395	ABC-type sugar transport system, permease component
Arad_0132	COG3622	Belongs to the hyi family
Arad_0134	COG2372	response to copper ion
Arad_0135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Arad_0136	COG1012	belongs to the aldehyde dehydrogenase family
Arad_0138	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Arad_0142	COG0539	negative regulation of cytoplasmic translation
Arad_0143	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Arad_0144	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Arad_0155	COG2860	membrane
Arad_0158	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Arad_0161	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Arad_0162	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Arad_0165	COG1185	polyribonucleotide nucleotidyltransferase activity
Arad_0169	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Arad_0170	COG2267	carboxylic ester hydrolase activity
Arad_0171	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Arad_0172	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Arad_0173	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Arad_0177	COG0779	Required for maturation of 30S ribosomal subunits
Arad_0178	COG2951	lytic endotransglycosylase activity
Arad_0179	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Arad_0184	COG1522	sequence-specific DNA binding
Arad_0185	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Arad_0186	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Arad_0188	COG2816	NAD+ diphosphatase activity
Arad_0189	COG2378	regulation of single-species biofilm formation
Arad_0193	COG1605	Chorismate mutase
Arad_0193	COG0077	Prephenate dehydratase
Arad_0195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Arad_0196	COG3474	cytochrome
Arad_0201	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_0206	COG2226	methyltransferase
Arad_0209	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Arad_0210	COG0484	heat shock protein binding
Arad_0212	COG0443	Heat shock 70 kDa protein
Arad_0213	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Arad_0223	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Arad_0226	COG1187	pseudouridine synthase activity
Arad_0228	COG0745	RESPONSE REGULATOR receiver
Arad_0229	COG2205	protein histidine kinase activity
Arad_0232	COG0840	transmembrane signaling receptor activity
Arad_0232	COG2972	Histidine kinase
Arad_0233	COG3842	ATPase activity
Arad_0235	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_0238	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Arad_0240	COG2200	EAL domain
Arad_0240	COG2199	diguanylate cyclase activity
Arad_0242	COG4957	zinc ion binding
Arad_0243	COG0306	phosphate transporter
Arad_0252	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Arad_0254	COG1845	cytochrome c oxidase, subunit III
Arad_0255	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Arad_0257	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Arad_0258	COG0477	Major facilitator Superfamily
Arad_0261	COG3842	ATPase activity
Arad_0263	COG1473	amidohydrolase
Arad_0264	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Arad_0266	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arad_0269	COG5001	Diguanylate cyclase
Arad_0269	COG3300	MHYT domain
Arad_0271	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Arad_0271	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Arad_0272	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Arad_0274	COG3454	Phosphonate metabolism
Arad_0276	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Arad_0277	COG3639	organic phosphonate transmembrane transporter activity
Arad_0281	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Arad_0285	COG4778	phosphonate C-P lyase system protein PhnL
Arad_0287	COG4107	phosphonate C-P lyase system protein PhnK
Arad_0288	COG3627	carbon phosphorus lyase activity
Arad_0289	COG3626	phosphonate metabolism
Arad_0291	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
Arad_0292	COG3624	Phosphonate C-P lyase system protein PhnG
Arad_0293	COG2188	Transcriptional regulator
Arad_0294	COG0588	phosphoglycerate mutase activity
Arad_0295	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Arad_0296	COG1132	(ABC) transporter
Arad_0297	COG0837	glucose binding
Arad_0298	COG1803	Methylglyoxal synthase
Arad_0300	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Arad_0303	COG4166	transmembrane transport
Arad_0305	COG4174	ABC transporter (Permease)
Arad_0306	COG4239	(ABC) transporter, permease
Arad_0307	COG4172	Belongs to the ABC transporter superfamily
Arad_0308	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_0309	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Arad_0314	COG0668	transmembrane transport
Arad_0318	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_0319	COG1902	pentaerythritol trinitrate reductase activity
Arad_0320	COG2267	carboxylic ester hydrolase activity
Arad_0326	COG0583	DNA-binding transcription factor activity
Arad_0328	COG2814	Major facilitator Superfamily
Arad_0330	COG0667	Aldo Keto reductase
Arad_0331	COG0583	DNA-binding transcription factor activity
Arad_0344	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Arad_0346	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Arad_0347	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Arad_0349	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Arad_0352	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Arad_0353	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Arad_0363	COG4964	Belongs to the GSP D family
Arad_0372	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Arad_0379	COG0154	amidase activity
Arad_0381	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_0383	COG0747	negative chemotaxis
Arad_0385	COG3191	aminopeptidase activity
Arad_0387	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arad_0393	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Arad_0400	COG0673	inositol 2-dehydrogenase activity
Arad_0403	COG0395	ABC-type sugar transport system, permease component
Arad_0406	COG3842	ATPase activity
Arad_0412	COG1737	Transcriptional regulator
Arad_0419	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Arad_0423	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Arad_0426	COG0481	GTPase activity
Arad_0432	COG5006	permease, DMT superfamily
Arad_0438	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Arad_0440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Arad_0441	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Arad_0444	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Arad_0445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arad_0445	COG0072	phenylalanine-tRNA ligase activity
Arad_0448	COG4953	penicillin-binding protein 1C
Arad_0451	COG0667	Aldo Keto reductase
Arad_0455	COG0667	Aldo Keto reductase
Arad_0456	COG4977	sequence-specific DNA binding
Arad_0466	COG1570	exodeoxyribonuclease VII activity
Arad_0467	COG2249	NAD(P)H dehydrogenase (quinone) activity
Arad_0468	COG2309	aminopeptidase activity
Arad_0472	COG1393	Belongs to the ArsC family
Arad_0477	COG2814	Major facilitator Superfamily
Arad_0484	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Arad_0486	COG0583	DNA-binding transcription factor activity
Arad_0487	COG2249	NAD(P)H dehydrogenase (quinone) activity
Arad_0489	COG1733	regulation of RNA biosynthetic process
Arad_0490	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_0493	COG3663	DNA glycosylase
Arad_0499	COG0583	DNA-binding transcription factor activity
Arad_0502	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_0504	COG2020	methyltransferase activity
Arad_0508	COG1309	transcriptional regulator
Arad_0510	COG0519	Catalyzes the synthesis of GMP from XMP
Arad_0510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Arad_0525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
Arad_0528	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Arad_0531	COG1968	undecaprenyl-diphosphatase activity
Arad_0538	COG0284	orotidine-5'-phosphate decarboxylase activity
Arad_0541	COG3963	phosphatidate phosphatase activity
Arad_0542	COG0592	DNA-directed DNA polymerase activity
Arad_0543	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Arad_0545	COG0792	nuclease activity
Arad_0549	COG0189	ligase activity
Arad_0553	COG1280	lysine exporter protein (LysE YggA)
Arad_0554	COG1335	isochorismatase
Arad_0555	COG1280	lysine exporter protein (LysE YggA)
Arad_0559	COG1522	sequence-specific DNA binding
Arad_0561	COG0756	dUTP diphosphatase activity
Arad_0562	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Arad_0567	COG0667	Aldo Keto reductase
Arad_0568	COG0583	DNA-binding transcription factor activity
Arad_0569	COG1720	tRNA m6t6A37 methyltransferase activity
Arad_0570	COG3585	molybdate ion transport
Arad_0571	COG3119	arylsulfatase activity
Arad_0572	COG0583	DNA-binding transcription factor activity
Arad_0573	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Arad_0574	COG1877	trehalose-phosphatase activity
Arad_0576	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Arad_0578	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_0579	COG0583	DNA-binding transcription factor activity
Arad_0580	COG0583	DNA-binding transcription factor activity
Arad_0581	COG2814	Major facilitator Superfamily
Arad_0586	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Arad_0591	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Arad_0592	COG2986	histidine ammonia-lyase
Arad_0594	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Arad_0595	COG2226	methyltransferase
Arad_0597	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Arad_0598	COG1024	Enoyl-CoA hydratase
Arad_0600	COG0268	Binds directly to 16S ribosomal RNA
Arad_0601	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Arad_0606	COG0697	spore germination
Arad_0608	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Arad_0609	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Arad_0611	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Arad_0612	COG1420	regulation of RNA biosynthetic process
Arad_0614	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Arad_0616	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Arad_0618	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Arad_0620	COG1137	ATPase activity
Arad_0622	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
Arad_0624	COG0616	signal peptide processing
Arad_0625	COG0776	regulation of translation
Arad_0631	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Arad_0632	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Arad_0633	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Arad_0638	COG0280	phosphate acetyltransferase
Arad_0638	COG0281	malic enzyme
Arad_0639	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Arad_0647	COG0180	Tryptophanyl-tRNA synthetase
Arad_0649	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Arad_0656	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arad_0657	COG1702	phosphate starvation-inducible protein PhoH
Arad_0658	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Arad_0660	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Arad_0661	COG1396	sequence-specific DNA binding
Arad_0663	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Arad_0665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Arad_0667	COG0071	Belongs to the small heat shock protein (HSP20) family
Arad_0669	COG0840	transmembrane signaling receptor activity
Arad_0670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_0674	COG0242	peptide deformylase activity
Arad_0679	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Arad_0680	COG0101	tRNA pseudouridine synthase activity
Arad_0682	COG0579	oxidoreductase
Arad_0684	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arad_0685	COG2171	N-acyltransferase activity
Arad_0694	COG0300	oxidoreductase activity
Arad_0695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Arad_0698	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Arad_0699	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Arad_0700	COG3708	Transcriptional regulator
Arad_0700	COG2207	Transcriptional regulator
Arad_0703	COG0706	membrane insertase activity
Arad_0704	COG0594	ribonuclease P activity
Arad_0705	COG2972	Histidine kinase
Arad_0705	COG0840	transmembrane signaling receptor activity
Arad_0713	COG1733	regulation of RNA biosynthetic process
Arad_0717	COG0477	Major facilitator Superfamily
Arad_0721	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Arad_0723	COG0583	DNA-binding transcription factor activity
Arad_0724	COG0300	oxidoreductase activity
Arad_0725	COG0667	Aldo Keto reductase
Arad_0729	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_0730	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_0731	COG3938	Belongs to the proline racemase family
Arad_0739	COG1072	(Pantothenic acid kinase))
Arad_0740	COG0418	dihydroorotase activity
Arad_0742	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Arad_0744	COG0166	Belongs to the GPI family
Arad_0745	COG0318	PFAM AMP-dependent synthetase and ligase
Arad_0748	COG0346	lactoylglutathione lyase activity
Arad_0750	COG3795	YCII-related domain
Arad_0751	COG1174	glycine betaine transport
Arad_0752	COG1125	glycine betaine transport
Arad_0753	COG1174	glycine betaine transport
Arad_0755	COG1732	Glycine betaine
Arad_0756	COG0583	DNA-binding transcription factor activity
Arad_0759	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Arad_0763	COG2326	polyphosphate kinase activity
Arad_0764	COG5002	protein histidine kinase activity
Arad_0768	COG0573	inorganic phosphate transmembrane transporter activity
Arad_0769	COG0581	inorganic phosphate transmembrane transporter activity
Arad_0770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Arad_0771	COG0704	Plays a role in the regulation of phosphate uptake
Arad_0772	COG0745	RESPONSE REGULATOR receiver
Arad_0775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arad_0776	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Arad_0778	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Arad_0779	COG2967	ApaG domain
Arad_0783	COG0717	Belongs to the dCTP deaminase family
Arad_0784	COG0110	maltose O-acetyltransferase activity
Arad_0791	COG0167	dihydroorotate dehydrogenase activity
Arad_0792	COG0534	Mate efflux family protein
Arad_0797	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
Arad_0799	COG0174	glutamine synthetase
Arad_0800	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Arad_0803	COG1201	RNA secondary structure unwinding
Arad_0808	COG0730	response to heat
Arad_0813	COG1960	acyl-CoA dehydrogenase activity
Arad_0815	COG0183	Belongs to the thiolase family
Arad_0816	COG1024	Enoyl-CoA hydratase
Arad_0816	COG1250	3-hydroxyacyl-CoA dehydrogenase
Arad_0821	COG1970	mechanosensitive ion channel activity
Arad_0832	COG0410	ABC transporter
Arad_0836	COG1024	Enoyl-CoA hydratase
Arad_0843	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Arad_0843	COG4651	solute:proton antiporter activity
Arad_0844	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Arad_0845	COG0840	transmembrane signaling receptor activity
Arad_0850	COG0643	Histidine kinase
Arad_0850	COG2198	Histidine kinase
Arad_0851	COG0835	chemotaxis
Arad_0852	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Arad_0853	COG2201	protein-glutamate methylesterase activity
Arad_0854	COG0745	RESPONSE REGULATOR receiver
Arad_0855	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Arad_0858	COG1766	The M ring may be actively involved in energy transduction
Arad_0859	COG2771	luxR family
Arad_0863	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Arad_0864	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arad_0867	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arad_0870	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arad_0871	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Arad_0873	COG4786	Flagellar basal body rod
Arad_0875	COG1157	protein secretion by the type III secretion system
Arad_0877	COG1815	bacterial-type flagellum-dependent cell motility
Arad_0879	COG1558	bacterial-type flagellum-dependent cell motility
Arad_0880	COG1677	Flagellar hook-basal body complex protein FliE
Arad_0881	COG4786	Flagellar basal body rod
Arad_0882	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
Arad_0884	COG1706	bacterial-type flagellum-dependent cell motility
Arad_0886	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Arad_0889	COG1338	Plays a role in the flagellum-specific transport system
Arad_0898	COG0076	glutamate decarboxylase activity
Arad_0900	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Arad_0910	COG1749	Flagellar hook protein flgE
Arad_0914	COG5443	negative regulation of bacterial-type flagellum assembly
Arad_0918	COG4794	Type iii secretion
Arad_0919	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Arad_0920	COG1684	flagellar biosynthetic protein fliR
Arad_0930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Arad_0931	COG1609	Transcriptional regulator
Arad_0932	COG1653	transport
Arad_0933	COG1175	transmembrane transport
Arad_0935	COG0395	ABC-type sugar transport system, permease component
Arad_0936	COG0366	Alpha amylase catalytic
Arad_0937	COG3842	ATPase activity
Arad_0942	COG0129	dihydroxy-acid dehydratase activity
Arad_0943	COG0363	glucosamine-6-phosphate deaminase activity
Arad_0944	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Arad_0945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_0948	COG2081	HI0933 family
Arad_0953	COG0840	transmembrane signaling receptor activity
Arad_0953	COG2972	Histidine kinase
Arad_0955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Arad_0957	COG3842	ATPase activity
Arad_0959	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_0960	COG1177	transmembrane transport
Arad_0962	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arad_0963	COG0513	Belongs to the DEAD box helicase family
Arad_0966	COG2205	protein histidine kinase activity
Arad_0978	COG4269	membrane
Arad_0980	COG1959	2 iron, 2 sulfur cluster binding
Arad_0982	COG0747	negative chemotaxis
Arad_0984	COG0601	transmembrane transport
Arad_0985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_0987	COG0444	Belongs to the ABC transporter superfamily
Arad_0988	COG4608	Belongs to the ABC transporter superfamily
Arad_0989	COG3265	gluconokinase activity
Arad_0990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_0991	COG1755	Isoprenylcysteine carboxyl methyltransferase
Arad_0995	COG1595	DNA-templated transcription, initiation
Arad_1000	COG0583	DNA-binding transcription factor activity
Arad_10005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_10009	COG1376	ErfK ybiS ycfS ynhG family protein
Arad_10012	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_10013	COG1473	amidohydrolase
Arad_10018	COG0436	Aminotransferase
Arad_1002	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Arad_10020	COG4302	ethanolamine ammonia-lyase activity
Arad_10021	COG4303	Ethanolamine ammonia lyase large subunit
Arad_10028	COG0235	Class ii aldolase
Arad_10030	COG3239	Fatty acid desaturase
Arad_10034	COG1116	anion transmembrane transporter activity
Arad_10036	COG3665	Urea carboxylase-associated protein
Arad_1004	COG0477	Major facilitator Superfamily
Arad_10042	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Arad_10051	COG0596	Alpha beta hydrolase
Arad_10054	COG0745	RESPONSE REGULATOR receiver
Arad_10055	COG2186	Transcriptional regulator
Arad_1014	COG0583	DNA-binding transcription factor activity
Arad_1017	COG0488	(ABC) transporter
Arad_1027	COG0306	phosphate transporter
Arad_1031	COG0583	DNA-binding transcription factor activity
Arad_1033	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Arad_1034	COG0583	DNA-binding transcription factor activity
Arad_1035	COG0277	FAD linked oxidase domain protein
Arad_1036	COG0277	FAD linked oxidase domain protein
Arad_1037	COG0247	lactate metabolic process
Arad_1040	COG1376	ErfK ybiS ycfS ynhG family protein
Arad_1041	COG1376	ErfK ybiS ycfS ynhG family protein
Arad_1042	COG2818	Glycosylase
Arad_1046	COG0667	Aldo Keto reductase
Arad_1048	COG3321	synthase
Arad_1048	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1048	COG0604	alcohol dehydrogenase
Arad_1049	COG0583	DNA-binding transcription factor activity
Arad_1055	COG0124	histidyl-tRNA synthetase
Arad_1056	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Arad_1058	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Arad_1062	COG2259	Doxx family
Arad_1064	COG0625	glutathione transferase activity
Arad_1068	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Arad_1072	COG0196	riboflavin kinase activity
Arad_1081	COG0590	tRNA wobble adenosine to inosine editing
Arad_1082	COG1187	pseudouridine synthase activity
Arad_1083	COG0742	ribosomal rna small subunit methyltransferase
Arad_1086	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Arad_1086	COG0475	glutathione-regulated potassium exporter activity
Arad_1087	COG0312	modulator of DNA gyrase
Arad_1088	COG0483	inositol monophosphate 1-phosphatase activity
Arad_1090	COG1519	Transferase
Arad_1092	COG1663	tetraacyldisaccharide 4'-kinase activity
Arad_1095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Arad_1096	COG0745	RESPONSE REGULATOR receiver
Arad_1097	COG3300	MHYT domain
Arad_1097	COG5001	Diguanylate cyclase
Arad_1098	COG1522	sequence-specific DNA binding
Arad_1099	COG0137	argininosuccinate synthase activity
Arad_1101	COG3386	PFAM SMP-30 Gluconolaconase
Arad_1102	COG0800	Aldolase
Arad_1103	COG3734	2-keto-3-deoxy-galactonokinase
Arad_1105	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1106	COG1414	Transcriptional regulator
Arad_1107	COG2197	response regulator
Arad_1109	COG0489	protein tyrosine kinase activity
Arad_1111	COG0598	Magnesium transport protein CorA
Arad_1113	COG3158	transport of potassium into the cell
Arad_1117	COG0356	it plays a direct role in the translocation of protons across the membrane
Arad_1119	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Arad_1120	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Arad_1121	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Arad_1124	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Arad_1128	COG0521	Mo-molybdopterin cofactor biosynthetic process
Arad_1130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Arad_1133	COG0142	geranyltranstransferase activity
Arad_1139	COG1396	sequence-specific DNA binding
Arad_1148	COG0752	glycyl-tRNA synthetase alpha subunit
Arad_1149	COG1704	LemA family
Arad_1151	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Arad_1155	COG0751	glycine-tRNA ligase activity
Arad_1157	COG1683	Conserved Protein
Arad_1158	COG0840	transmembrane signaling receptor activity
Arad_1161	COG0151	Belongs to the GarS family
Arad_1162	COG2183	response to ionizing radiation
Arad_1163	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Arad_1166	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Arad_1173	COG0277	FAD linked oxidase domain protein
Arad_1174	COG0009	L-threonylcarbamoyladenylate synthase
Arad_1180	COG4638	Rieske (2fe-2S)
Arad_1187	COG1960	acyl-CoA dehydrogenase activity
Arad_1191	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Arad_1195	COG0840	transmembrane signaling receptor activity
Arad_1198	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Arad_1200	COG1741	Belongs to the pirin family
Arad_12013	COG0776	regulation of translation
Arad_12019	COG1192	Involved in chromosome partitioning
Arad_1202	COG1722	exodeoxyribonuclease VII activity
Arad_12020	COG1475	DNA binding
Arad_12022	COG1414	Transcriptional regulator
Arad_12024	COG1396	sequence-specific DNA binding
Arad_1203	COG0123	including yeast histone deacetylase and acetoin utilization protein
Arad_12038	COG1192	Involved in chromosome partitioning
Arad_1206	COG1268	BioY protein
Arad_12064	COG3451	type IV secretory pathway VirB4
Arad_12072	COG2948	multi-organism process
Arad_12073	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
Arad_1208	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Arad_1209	COG1122	ATPase activity
Arad_12091	COG0534	Mate efflux family protein
Arad_12096	COG0367	asparagine synthase
Arad_12097	COG0561	phosphatase activity
Arad_12098	COG0488	(ABC) transporter
Arad_1210	COG3214	Protein conserved in bacteria
Arad_12100	COG4372	Transposase
Arad_12107	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_12108	COG3436	PFAM IS66 Orf2 family protein
Arad_12109	COG2963	transposase activity
Arad_1211	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Arad_1211	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Arad_12120	COG0235	Class ii aldolase
Arad_12125	COG1414	Transcriptional regulator
Arad_12126	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1213	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Arad_12135	COG1063	alcohol dehydrogenase
Arad_12137	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_12138	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_12139	COG1129	ABC transporter
Arad_12140	COG1879	ABC-type sugar transport system periplasmic component
Arad_12146	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Arad_12147	COG2086	electron transfer activity
Arad_12152	COG1126	abc transporter atp-binding protein
Arad_12153	COG0765	amino acid transport
Arad_12155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_12158	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_12158	COG2022	thiamine diphosphate biosynthetic process
Arad_1216	COG0406	alpha-ribazole phosphatase activity
Arad_12162	COG0583	DNA-binding transcription factor activity
Arad_12163	COG1942	4-Oxalocrotonate Tautomerase
Arad_1217	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Arad_12173	COG1175	transmembrane transport
Arad_12175	COG0395	ABC-type sugar transport system, permease component
Arad_1218	COG0484	heat shock protein binding
Arad_12180	COG2207	Transcriptional regulator
Arad_12180	COG1917	Cupin 2, conserved barrel domain protein
Arad_12181	COG0840	transmembrane signaling receptor activity
Arad_12186	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arad_12198	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Arad_12199	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Arad_1220	COG0259	pyridoxamine-phosphate oxidase activity
Arad_12202	COG0411	ABC transporter
Arad_12206	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_12209	COG4638	Rieske (2fe-2S)
Arad_12211	COG3485	protocatechuate 3,4-dioxygenase
Arad_12216	COG1012	belongs to the aldehyde dehydrogenase family
Arad_1222	COG1686	Belongs to the peptidase S11 family
Arad_12223	COG0583	DNA-binding transcription factor activity
Arad_12224	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arad_12225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arad_12230	COG1271	oxidase subunit
Arad_12231	COG1294	oxidase, subunit
Arad_12234	COG0028	Belongs to the TPP enzyme family
Arad_12239	COG2514	catechol 2,3-dioxygenase activity
Arad_1224	COG0312	modulator of DNA gyrase
Arad_12240	COG0435	Glutathione S-transferase
Arad_12241	COG0400	carboxylic ester hydrolase activity
Arad_12242	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_12260	COG0601	transmembrane transport
Arad_12266	COG0154	amidase activity
Arad_1227	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Arad_12272	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Arad_12273	COG0459	protein refolding
Arad_1228	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Arad_12282	COG2086	electron transfer activity
Arad_12284	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Arad_1229	COG0109	protoheme IX farnesyltransferase activity
Arad_12290	COG0431	NADPH-dependent FMN reductase
Arad_12302	COG1233	COG1233 Phytoene dehydrogenase and related
Arad_12303	COG1073	alpha beta
Arad_12304	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arad_12307	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1231	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Arad_12313	COG1733	regulation of RNA biosynthetic process
Arad_12315	COG1309	transcriptional regulator
Arad_12316	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_12317	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_12318	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_12321	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Arad_12333	COG1053	succinate dehydrogenase
Arad_1234	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arad_12342	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_12343	COG1116	anion transmembrane transporter activity
Arad_12344	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_12346	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_12348	COG1484	DNA-dependent DNA replication
Arad_1235	COG0640	Transcriptional regulator
Arad_12353	COG0601	transmembrane transport
Arad_12354	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_12355	COG4172	Belongs to the ABC transporter superfamily
Arad_12362	COG4172	Belongs to the ABC transporter superfamily
Arad_12364	COG3842	ATPase activity
Arad_12365	COG0395	ABC-type sugar transport system, permease component
Arad_12372	COG2379	hydroxypyruvate reductase
Arad_12376	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_12379	COG1879	ABC-type sugar transport system periplasmic component
Arad_12380	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_12383	COG1129	ABC transporter
Arad_12385	COG1082	Xylose isomerase domain protein TIM barrel
Arad_12386	COG1940	carbohydrate kinase activity
Arad_12387	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_12388	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
Arad_12394	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arad_12396	COG1879	ABC-type sugar transport system periplasmic component
Arad_12397	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_12398	COG1129	ABC transporter
Arad_12400	COG1116	anion transmembrane transporter activity
Arad_12408	COG0747	negative chemotaxis
Arad_12411	COG1960	acyl-CoA dehydrogenase activity
Arad_12412	COG0583	DNA-binding transcription factor activity
Arad_12413	COG0596	Alpha beta hydrolase
Arad_12415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_12416	COG4597	amino acid ABC transporter
Arad_12417	COG0765	amino acid transport
Arad_1242	COG3346	SURF1 family
Arad_12425	COG0601	transmembrane transport
Arad_12429	COG0747	negative chemotaxis
Arad_12434	COG0601	transmembrane transport
Arad_12435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_12438	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_1244	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Arad_12440	COG4552	Acetyltransferase involved in intracellular survival and related
Arad_12443	COG0572	uridine kinase
Arad_12444	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_12446	COG0776	regulation of translation
Arad_1245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Arad_12454	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Arad_12457	COG0697	spore germination
Arad_12458	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Arad_1246	COG0328	RNA-DNA hybrid ribonuclease activity
Arad_12462	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_12463	COG0601	transmembrane transport
Arad_12466	COG1126	abc transporter atp-binding protein
Arad_12467	COG0765	amino acid transport
Arad_12468	COG0765	amino acid transport
Arad_12477	COG4372	Transposase
Arad_12478	COG3436	PFAM IS66 Orf2 family protein
Arad_12480	COG2963	transposase activity
Arad_12482	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_12483	COG0583	DNA-binding transcription factor activity
Arad_12485	COG0154	amidase activity
Arad_1249	COG0803	Belongs to the bacterial solute-binding protein 9 family
Arad_12494	COG0753	catalase activity
Arad_12496	COG2801	Transposase and inactivated derivatives
Arad_12496	COG3415	Transposase
Arad_1251	COG1121	(ABC) transporter
Arad_1253	COG0678	peroxiredoxin activity
Arad_1253	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Arad_1256	COG1678	Uncharacterized ACR, COG1678
Arad_1261	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Arad_1262	COG0612	Peptidase, M16
Arad_1267	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arad_1269	COG1268	BioY protein
Arad_1271	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Arad_1275	COG2189	Belongs to the N(4) N(6)-methyltransferase family
Arad_1280	COG1194	a g-specific adenine glycosylase
Arad_1282	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Arad_1283	COG1196	nuclear chromosome segregation
Arad_1285	COG1253	flavin adenine dinucleotide binding
Arad_1286	COG3093	addiction module antidote protein HigA
Arad_1288	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Arad_1288	COG0574	Belongs to the PEP-utilizing enzyme family
Arad_1325	COG1956	GAF domain-containing protein
Arad_1329	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Arad_1335	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Arad_1339	COG0477	Major facilitator Superfamily
Arad_1342	COG2895	sulfate adenylyltransferase (ATP) activity
Arad_1343	COG0175	sulfate reduction
Arad_1345	COG0175	sulfate reduction
Arad_1347	COG1959	2 iron, 2 sulfur cluster binding
Arad_1348	COG0038	chloride channel
Arad_1351	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Arad_1352	COG1012	belongs to the aldehyde dehydrogenase family
Arad_1353	COG0625	glutathione transferase activity
Arad_1354	COG1309	transcriptional regulator
Arad_1358	COG4943	cyclic-guanylate-specific phosphodiesterase activity
Arad_1359	COG1063	alcohol dehydrogenase
Arad_1364	COG1349	DNA-binding transcription factor activity
Arad_1365	COG0625	glutathione transferase activity
Arad_1373	COG1960	acyl-CoA dehydrogenase activity
Arad_1374	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Arad_1382	COG1793	dna ligase
Arad_1387	COG1376	ErfK ybiS ycfS ynhG family protein
Arad_1389	COG1376	ErfK ybiS ycfS ynhG family protein
Arad_1390	COG1846	Transcriptional regulator
Arad_1391	COG1764	response to oxidative stress
Arad_1394	COG1846	Transcriptional regulator
Arad_1399	COG0433	COG0433 Predicted ATPase
Arad_14001	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_14002	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_1403	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Arad_14035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Arad_1405	COG4106	trans-aconitate 2-methyltransferase activity
Arad_14050	COG1475	DNA binding
Arad_14056	COG2824	Alkylphosphonate utilization operon protein PhnA
Arad_1406	COG1064	alcohol dehydrogenase
Arad_14066	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Arad_14069	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_14076	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_14079	COG5489	Protein of unknown function (DUF736)
Arad_1408	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Arad_14100	COG1126	abc transporter atp-binding protein
Arad_14101	COG0765	amino acid transport
Arad_1411	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Arad_14123	COG0584	glycerophosphoryl diester phosphodiesterase
Arad_14126	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_14129	COG0444	Belongs to the ABC transporter superfamily
Arad_14137	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_14138	COG0601	transmembrane transport
Arad_14140	COG4172	Belongs to the ABC transporter superfamily
Arad_14141	COG0444	Belongs to the ABC transporter superfamily
Arad_14142	COG0747	negative chemotaxis
Arad_14145	COG2390	Transcriptional regulator
Arad_14157	COG0145	ligase activity
Arad_1416	COG2814	Major facilitator Superfamily
Arad_14160	COG0583	DNA-binding transcription factor activity
Arad_1417	COG1881	PFAM PEBP family protein
Arad_14170	COG3701	Conjugal transfer protein
Arad_14172	COG3846	protein secretion by the type IV secretion system
Arad_14175	COG5314	conjugation
Arad_14177	COG3451	type IV secretory pathway VirB4
Arad_14181	COG4962	Type ii secretion system protein e
Arad_14184	COG1192	Involved in chromosome partitioning
Arad_14185	COG1475	DNA binding
Arad_14186	COG0640	Transcriptional regulator
Arad_14187	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_14199	COG0583	DNA-binding transcription factor activity
Arad_14202	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_14203	COG1116	anion transmembrane transporter activity
Arad_14204	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_14206	COG1879	ABC-type sugar transport system periplasmic component
Arad_14207	COG1129	ABC transporter
Arad_14208	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_14213	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_14214	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Arad_14222	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_14223	COG1129	ABC transporter
Arad_14227	COG0747	negative chemotaxis
Arad_14229	COG4172	Belongs to the ABC transporter superfamily
Arad_14231	COG0601	transmembrane transport
Arad_14234	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_14236	COG0583	DNA-binding transcription factor activity
Arad_14240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arad_1426	COG1278	Cold shock
Arad_1428	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Arad_1432	COG2207	Transcriptional regulator
Arad_1433	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1437	COG1280	lysine exporter protein (LysE YggA)
Arad_1441	COG2010	Cytochrome c
Arad_1442	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Arad_1451	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Arad_1461	COG2514	catechol 2,3-dioxygenase activity
Arad_1464	COG1272	protein, Hemolysin III
Arad_1466	COG1247	-acetyltransferase
Arad_1469	COG2111	Na H antiporter
Arad_1470	COG1006	Multisubunit Na H antiporter MnhC subunit
Arad_1472	COG1863	multisubunit Na H antiporter MnhE subunit
Arad_1473	COG2212	antiporter activity
Arad_1474	COG1320	monovalent cation:proton antiporter activity
Arad_1475	COG4957	zinc ion binding
Arad_1476	COG2166	iron-sulfur cluster assembly
Arad_1478	COG2205	protein histidine kinase activity
Arad_1486	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Arad_1487	COG2983	Belongs to the UPF0260 family
Arad_1490	COG0745	RESPONSE REGULATOR receiver
Arad_1491	COG2205	protein histidine kinase activity
Arad_1493	COG4235	cytochrome complex assembly
Arad_1494	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Arad_1495	COG1138	Cytochrome C-type biogenesis protein
Arad_1496	COG3088	subunit of a heme lyase
Arad_1497	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Arad_1499	COG0745	RESPONSE REGULATOR receiver
Arad_1500	COG2205	protein histidine kinase activity
Arad_15002	COG0495	leucyl-tRNA aminoacylation
Arad_15006	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_15008	COG1132	(ABC) transporter
Arad_15014	COG1475	DNA binding
Arad_1502	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Arad_15023	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Arad_15026	COG0469	pyruvate kinase activity
Arad_15028	COG0574	Belongs to the PEP-utilizing enzyme family
Arad_15028	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Arad_1503	COG2205	protein histidine kinase activity
Arad_1503	COG2202	Pas domain
Arad_15032	COG1619	proteins homologs of microcin C7 resistance protein MccF
Arad_15034	COG2226	methyltransferase
Arad_15036	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1504	COG0308	aminopeptidase N
Arad_1505	COG3290	protein histidine kinase activity
Arad_1505	COG0840	transmembrane signaling receptor activity
Arad_1510	COG1573	uracil-dna glycosylase
Arad_1511	COG0443	Heat shock 70 kDa protein
Arad_1513	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_1515	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1521	COG2239	Acts as a magnesium transporter
Arad_1524	COG1733	regulation of RNA biosynthetic process
Arad_1525	COG2814	Major facilitator Superfamily
Arad_1528	COG0174	glutamine synthetase
Arad_1532	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Arad_1533	COG0463	Glycosyl transferase, family 2
Arad_1535	COG4941	Belongs to the sigma-70 factor family
Arad_1537	COG3795	YCII-related domain
Arad_1540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Arad_1547	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arad_1555	COG3718	enzyme involved in inositol metabolism
Arad_1557	COG1082	Xylose isomerase domain protein TIM barrel
Arad_1558	COG3962	Belongs to the TPP enzyme family
Arad_1559	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_1562	COG0673	inositol 2-dehydrogenase activity
Arad_1568	COG0798	PFAM Bile acid sodium symporter
Arad_1571	COG0640	Transcriptional regulator
Arad_1580	COG0596	Alpha beta hydrolase
Arad_1580	COG2945	thiolester hydrolase activity
Arad_1581	COG0741	lytic transglycosylase activity
Arad_1582	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_1583	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Arad_1586	COG1758	RNA polymerase activity
Arad_1591	COG0736	holo-[acyl-carrier-protein] synthase activity
Arad_1592	COG0681	Belongs to the peptidase S26 family
Arad_1593	COG0571	ribonuclease III activity
Arad_1595	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Arad_1597	COG1381	Involved in DNA repair and RecF pathway recombination
Arad_1600	COG1418	mRNA catabolic process
Arad_1604	COG2032	superoxide dismutase activity
Arad_1608	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Arad_1609	COG0354	folic acid binding
Arad_1616	COG1742	UPF0060 membrane protein
Arad_1620	COG1183	phosphatidylcholine synthase activity
Arad_1622	COG0688	phosphatidylethanolamine metabolic process
Arad_1623	COG0671	phosphoesterase, PA-phosphatase related
Arad_1624	COG5265	(ABC) transporter
Arad_1630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arad_1637	COG0215	cysteine-tRNA ligase activity
Arad_1639	COG4221	oxidoreductase activity
Arad_1640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Arad_1642	COG1286	toxin biosynthetic process
Arad_1644	COG1280	lysine exporter protein (LysE YggA)
Arad_1645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Arad_1646	COG0305	Participates in initiation and elongation during chromosome replication
Arad_1655	COG0359	binds to the 23S rRNA
Arad_1657	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Arad_1658	COG0360	Binds together with S18 to 16S ribosomal RNA
Arad_1665	COG0667	Aldo Keto reductase
Arad_1666	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Arad_1671	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Arad_1672	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Arad_1673	COG1561	YicC-like family, N-terminal region
Arad_1675	COG0194	GDP metabolic process
Arad_1676	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Arad_1677	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Arad_1681	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Arad_1684	COG0671	phosphoesterase, PA-phosphatase related
Arad_1686	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Arad_1693	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Arad_1694	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Arad_1695	COG1505	serine-type exopeptidase activity
Arad_1698	COG0488	(ABC) transporter
Arad_1702	COG0105	UTP biosynthetic process
Arad_1709	COG0314	molybdopterin synthase activity
Arad_1711	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Arad_1712	COG0322	excinuclease ABC activity
Arad_1713	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1718	COG0625	glutathione transferase activity
Arad_1720	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Arad_1721	COG0243	molybdopterin cofactor binding
Arad_1723	COG3454	Phosphonate metabolism
Arad_1724	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Arad_1725	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Arad_1726	COG0628	permease
Arad_1728	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Arad_1729	COG0248	Ppx GppA phosphatase
Arad_1731	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Arad_1732	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Arad_1733	COG2132	Multicopper oxidase
Arad_1734	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Arad_1740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Arad_1741	COG3654	unkown
Arad_1744	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Arad_1746	COG0113	porphobilinogen synthase activity
Arad_1752	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Arad_1753	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Arad_1754	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arad_1754	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Arad_1756	COG0454	-acetyltransferase
Arad_1760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Arad_1762	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Arad_1764	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Arad_1770	COG0416	fatty acid biosynthetic process
Arad_1772	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Arad_1773	COG0776	regulation of translation
Arad_1786	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
Arad_1787	COG4423	Transcription factor
Arad_1791	COG0438	transferase activity, transferring glycosyl groups
Arad_1800	COG1612	heme a metabolic process
Arad_1804	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Arad_1805	COG0010	Belongs to the arginase family
Arad_1810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Arad_1812	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Arad_1816	COG1832	CoA-binding protein
Arad_1821	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Arad_1823	COG0573	inorganic phosphate transmembrane transporter activity
Arad_1826	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Arad_1828	COG3706	GGDEF domain
Arad_1829	COG0740	serine-type endopeptidase activity
Arad_1831	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Arad_1832	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Arad_1833	COG0776	regulation of translation
Arad_1834	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_1835	COG0667	Aldo Keto reductase
Arad_1836	COG0420	3'-5' exonuclease activity
Arad_1837	COG4717	serine-type aminopeptidase activity
Arad_1839	COG1216	Glycosyl transferase, family 2
Arad_1839	COG0438	transferase activity, transferring glycosyl groups
Arad_1842	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arad_1843	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arad_1844	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arad_1846	COG0649	NAD binding
Arad_1848	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Arad_1849	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Arad_1851	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Arad_1851	COG3743	rRNA binding
Arad_1855	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Arad_1857	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Arad_1860	COG0713	ATP synthesis coupled electron transport
Arad_1863	COG1007	ATP synthesis coupled electron transport
Arad_1870	COG0442	prolyl-tRNA aminoacylation
Arad_1872	COG1136	(ABC) transporter
Arad_1876	COG0587	DNA-directed DNA polymerase activity
Arad_1879	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Arad_1884	COG0784	Response regulator, receiver
Arad_1885	COG3706	GGDEF domain
Arad_1885	COG0745	RESPONSE REGULATOR receiver
Arad_1886	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Arad_1887	COG2814	Major facilitator Superfamily
Arad_1890	COG0557	exoribonuclease II activity
Arad_1891	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Arad_1893	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Arad_1893	COG0758	DNA mediated transformation
Arad_1894	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Arad_1897	COG0540	Belongs to the ATCase OTCase family
Arad_1899	COG1960	acyl-CoA dehydrogenase activity
Arad_1900	COG3609	addiction module antidote protein, CC2985 family
Arad_1902	COG0456	acetyltransferase
Arad_1906	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Arad_1907	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Arad_1908	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arad_1909	COG0154	amidase activity
Arad_1912	COG3811	Belongs to the UPF0386 family
Arad_1914	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Arad_1920	COG4765	Protein conserved in bacteria
Arad_1924	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Arad_1928	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Arad_1930	COG0436	Aminotransferase
Arad_1932	COG1530	ribonuclease E activity
Arad_1933	COG0860	N-Acetylmuramoyl-L-alanine amidase
Arad_1936	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Arad_1939	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Arad_1949	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Arad_1950	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Arad_1957	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Arad_1958	COG0081	regulation of translation
Arad_1959	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Arad_1960	COG0222	ribosome binding
Arad_1962	COG0085	RNA polymerase activity
Arad_1963	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Arad_1966	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Arad_1967	COG0049	tRNA binding
Arad_1968	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Arad_1970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Arad_1971	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Arad_1973	COG0088	Forms part of the polypeptide exit tunnel
Arad_1974	COG0089	rRNA binding
Arad_1975	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Arad_1977	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Arad_1978	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Arad_1979	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Arad_1980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Arad_1982	COG0255	Belongs to the universal ribosomal protein uL29 family
Arad_1983	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Arad_1985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Arad_1986	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Arad_1988	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Arad_1990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Arad_1991	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Arad_1992	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Arad_1994	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Arad_1995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Arad_1998	COG0200	Binds to the 23S rRNA
Arad_2000	COG0201	protein transport
Arad_2002	COG0563	adenylate kinase activity
Arad_2003	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Arad_2004	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Arad_2005	COG0202	RNA polymerase activity
Arad_2007	COG0203	ribosomal protein L17
Arad_2015	COG1289	transmembrane transporter activity
Arad_2017	COG1566	PFAM secretion protein HlyD family protein
Arad_2020	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Arad_2021	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Arad_2022	COG0129	dihydroxy-acid dehydratase activity
Arad_2026	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Arad_2030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_2032	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Arad_2038	COG0488	(ABC) transporter
Arad_2040	COG1253	flavin adenine dinucleotide binding
Arad_2045	COG0789	Transcriptional regulator
Arad_2048	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_2051	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Arad_2052	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Arad_2056	COG1058	Belongs to the CinA family
Arad_2056	COG1546	Belongs to the CinA family
Arad_2057	COG0655	NAD(P)H dehydrogenase (quinone) activity
Arad_2059	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Arad_2061	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Arad_2065	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_2068	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Arad_2069	COG0583	DNA-binding transcription factor activity
Arad_2070	COG0737	Belongs to the 5'-nucleotidase family
Arad_2073	COG1522	sequence-specific DNA binding
Arad_2074	COG0686	Belongs to the AlaDH PNT family
Arad_2078	COG2897	thiosulfate sulfurtransferase activity
Arad_2079	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Arad_2081	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Arad_2082	COG0300	oxidoreductase activity
Arad_2083	COG3842	ATPase activity
Arad_2086	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Arad_2088	COG0395	ABC-type sugar transport system, permease component
Arad_2089	COG1175	transmembrane transport
Arad_2092	COG1653	transport
Arad_2106	COG2755	lipolytic protein G-D-S-L family
Arad_2106	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Arad_2107	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Arad_2111	COG0525	valine-tRNA ligase activity
Arad_2118	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Arad_2119	COG0018	arginyl-trna synthetase
Arad_2121	COG1472	Belongs to the glycosyl hydrolase 3 family
Arad_2122	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Arad_2126	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Arad_2127	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Arad_2129	COG0805	protein transport
Arad_2130	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Arad_2132	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Arad_2133	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Arad_2134	COG0739	heme binding
Arad_2142	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Arad_2148	COG0544	peptidyl-prolyl cis-trans isomerase activity
Arad_2156	COG0024	Methionine aminopeptidase
Arad_2157	COG1489	DNA binding
Arad_2158	COG3243	poly(R)-hydroxyalkanoic acid synthase
Arad_2161	COG0436	Aminotransferase
Arad_2163	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Arad_2165	COG2186	Transcriptional regulator
Arad_2173	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_2176	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_2184	COG1278	Cold shock
Arad_2190	COG1280	lysine exporter protein (LysE YggA)
Arad_2191	COG1522	sequence-specific DNA binding
Arad_2194	COG1126	abc transporter atp-binding protein
Arad_2196	COG0765	amino acid transport
Arad_2198	COG4597	amino acid ABC transporter
Arad_2199	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_2201	COG0626	cystathionine gamma-synthase activity
Arad_2211	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Arad_2213	COG0537	adenosine 5'-monophosphoramidase activity
Arad_2219	COG0052	Belongs to the universal ribosomal protein uS2 family
Arad_2220	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Arad_2222	COG0528	UMP kinase activity
Arad_2223	COG0233	cytoplasmic translational termination
Arad_2224	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Arad_2226	COG0750	zinc metalloprotease
Arad_2227	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Arad_2229	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Arad_2231	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Arad_2232	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Arad_2233	COG3494	Protein of unknown function (DUF1009)
Arad_2234	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Arad_2240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Arad_2242	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Arad_2243	COG0148	phosphopyruvate hydratase activity
Arad_2246	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Arad_2247	COG0022	dehydrogenase e1 component
Arad_2247	COG0508	dehydrogenase complex catalyzes the overall conversion of
Arad_2249	COG0508	dehydrogenase complex catalyzes the overall conversion of
Arad_2251	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Arad_2255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Arad_2261	COG1546	Belongs to the CinA family
Arad_2262	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Arad_2262	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Arad_2264	COG3852	Histidine kinase
Arad_2265	COG2204	response regulator
Arad_2267	COG5000	phosphorelay sensor kinase activity
Arad_2268	COG2204	response regulator
Arad_2269	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Arad_2271	COG1923	regulation of RNA biosynthetic process
Arad_2272	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Arad_2273	COG3956	TIGRFAM MazG family protein
Arad_2277	COG1648	precorrin-2 dehydrogenase activity
Arad_2277	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Arad_2279	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arad_2339	COG0785	Cytochrome C biogenesis protein
Arad_2340	COG0679	Auxin Efflux Carrier
Arad_2343	COG1183	phosphatidylcholine synthase activity
Arad_2350	COG1879	ABC-type sugar transport system periplasmic component
Arad_2352	COG1129	ABC transporter
Arad_2353	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_2354	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_2355	COG2186	Transcriptional regulator
Arad_2356	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Arad_2357	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Arad_2361	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Arad_2364	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Arad_2372	COG0174	glutamine synthetase
Arad_2373	COG0347	Belongs to the P(II) protein family
Arad_2375	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Arad_2375	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Arad_2377	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Arad_2379	COG0629	single-stranded DNA binding
Arad_2380	COG2095	MarC family integral membrane protein
Arad_2382	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Arad_2387	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Arad_2388	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Arad_2390	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Arad_2393	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Arad_2394	COG0343	queuine tRNA-ribosyltransferase activity
Arad_2398	COG3773	Cell wall hydrolase
Arad_2398	COG3409	Peptidoglycan-binding domain 1 protein
Arad_2401	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Arad_2402	COG1733	regulation of RNA biosynthetic process
Arad_2404	COG1132	(ABC) transporter
Arad_2405	COG1132	(ABC) transporter
Arad_2406	COG0583	DNA-binding transcription factor activity
Arad_2413	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Arad_2413	COG0321	lipoyl(octanoyl) transferase activity
Arad_2416	COG0084	hydrolase, TatD family'
Arad_2417	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arad_2418	COG0730	response to heat
Arad_2423	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Arad_2428	COG2094	Belongs to the DNA glycosylase MPG family
Arad_2437	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Arad_2438	COG0134	indole-3-glycerol-phosphate synthase activity
Arad_2440	COG0315	cyclic pyranopterin monophosphate synthase activity
Arad_2442	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Arad_2445	COG0372	Belongs to the citrate synthase family
Arad_2446	COG0372	Belongs to the citrate synthase family
Arad_2454	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Arad_2457	COG0504	CTP synthase activity
Arad_2458	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Arad_2459	COG0149	triose-phosphate isomerase activity
Arad_2462	COG0187	DNA topoisomerase II activity
Arad_2464	COG0628	permease
Arad_2472	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Arad_2474	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Arad_2476	COG0302	gtp cyclohydrolase
Arad_2477	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Arad_2478	COG1752	Esterase of the alpha-beta hydrolase superfamily
Arad_2486	COG2267	carboxylic ester hydrolase activity
Arad_2491	COG1686	Belongs to the peptidase S11 family
Arad_2497	COG1760	l-serine dehydratase
Arad_2502	COG2239	Acts as a magnesium transporter
Arad_2503	COG0242	peptide deformylase activity
Arad_2505	COG0321	lipoyl(octanoyl) transferase activity
Arad_2510	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Arad_2512	COG1671	Belongs to the UPF0178 family
Arad_2513	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Arad_2514	COG2076	Multidrug Resistance protein
Arad_2515	COG2259	Doxx family
Arad_2516	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Arad_2519	COG0546	phosphoglycolate phosphatase activity
Arad_2526	COG0509	glycine decarboxylation via glycine cleavage system
Arad_2527	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Arad_2527	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Arad_2528	COG0400	carboxylic ester hydrolase activity
Arad_2529	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Arad_2532	COG0316	Belongs to the HesB IscA family
Arad_2534	COG2151	metal-sulfur cluster biosynthetic enzyme
Arad_2535	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Arad_2536	COG0719	Fe-S assembly protein
Arad_2537	COG0396	ATPase activity
Arad_2539	COG0719	Fe-S assembly protein
Arad_2542	COG2945	thiolester hydrolase activity
Arad_2548	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Arad_2549	COG0346	lactoylglutathione lyase activity
Arad_2551	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Arad_2552	COG2833	Protein of unknown function (DUF455)
Arad_2553	COG0741	lytic transglycosylase activity
Arad_2553	COG0739	heme binding
Arad_2553	COG1196	nuclear chromosome segregation
Arad_2554	COG0513	Belongs to the DEAD box helicase family
Arad_2556	COG1051	belongs to the nudix hydrolase family
Arad_2558	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Arad_2559	COG3608	succinylglutamate desuccinylase aspartoacylase
Arad_2559	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Arad_2563	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Arad_2564	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_2568	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Arad_2573	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Arad_2574	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arad_2576	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
Arad_2577	COG0047	phosphoribosylformylglycinamidine synthase activity
Arad_2582	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arad_2585	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Arad_2592	COG2814	Major facilitator Superfamily
Arad_2593	COG2814	Major facilitator Superfamily
Arad_2595	COG0483	inositol monophosphate 1-phosphatase activity
Arad_2597	COG0483	inositol monophosphate 1-phosphatase activity
Arad_2599	COG0037	tRNA processing
Arad_2601	COG2066	Belongs to the glutaminase family
Arad_2602	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Arad_2606	COG1304	FMN binding
Arad_2609	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Arad_2613	COG0538	isocitrate dehydrogenase activity
Arad_2616	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
Arad_2617	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Arad_2618	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Arad_2620	COG2313	pseudouridylate synthase activity
Arad_2628	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Arad_2631	COG3106	COG3106 Predicted ATPase
Arad_2632	COG3768	UPF0283 membrane protein
Arad_2637	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Arad_2639	COG0633	Ferredoxin
Arad_2646	COG3507	Belongs to the glycosyl hydrolase 43 family
Arad_2647	COG0667	Aldo Keto reductase
Arad_2648	COG0673	inositol 2-dehydrogenase activity
Arad_2653	COG0395	ABC-type sugar transport system, permease component
Arad_2660	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Arad_2662	COG0456	acetyltransferase
Arad_2666	COG1127	ABC transporter
Arad_2667	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Arad_2668	COG2814	Major facilitator Superfamily
Arad_2672	COG0281	malic enzyme
Arad_2672	COG0280	phosphate acetyltransferase
Arad_2675	COG0823	Involved in the tonB-independent uptake of proteins
Arad_2677	COG1368	sulfuric ester hydrolase activity
Arad_2682	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Arad_2687	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Arad_2688	COG0546	phosphoglycolate phosphatase activity
Arad_2690	COG2989	Protein conserved in bacteria
Arad_2691	COG0114	fumarate hydratase activity
Arad_2695	COG3706	GGDEF domain
Arad_2698	COG1846	Transcriptional regulator
Arad_2701	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Arad_2704	COG0840	transmembrane signaling receptor activity
Arad_2704	COG2972	Histidine kinase
Arad_2705	COG0697	spore germination
Arad_2706	COG0746	molybdenum cofactor guanylyltransferase activity
Arad_2707	COG1763	Mo-molybdopterin cofactor biosynthetic process
Arad_2710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_2714	COG5425	PFAM Usg family protein
Arad_2718	COG0640	Transcriptional regulator
Arad_2720	COG1116	anion transmembrane transporter activity
Arad_2721	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_2722	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_2723	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_2725	COG2084	Dehydrogenase
Arad_2726	COG1522	sequence-specific DNA binding
Arad_2728	COG1573	uracil-dna glycosylase
Arad_2731	COG2205	protein histidine kinase activity
Arad_2731	COG2202	Pas domain
Arad_2733	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Arad_2734	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Arad_2737	COG0697	spore germination
Arad_2741	COG0842	Transport permease protein
Arad_2742	COG1131	(ABC) transporter
Arad_2745	COG1607	acyl-coa hydrolase
Arad_2753	COG2814	Major facilitator Superfamily
Arad_2754	COG0556	nucleotide-excision repair
Arad_2757	COG1278	Cold shock
Arad_2759	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Arad_2760	COG0179	Fumarylacetoacetate (FAA) hydrolase
Arad_2764	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Arad_2765	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Arad_2767	COG0523	cobalamin synthesis protein
Arad_2775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Arad_2779	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Arad_2796	COG1917	Cupin 2, conserved barrel domain protein
Arad_2802	COG1492	cobalamin metabolic process
Arad_2806	COG4176	ABC-type proline glycine betaine transport system permease component
Arad_2808	COG0517	IMP dehydrogenase activity
Arad_2808	COG4175	Glycine betaine
Arad_2810	COG1410	methionine synthase
Arad_2810	COG0646	methionine synthase
Arad_2818	COG5598	trimethylamine methyltransferase
Arad_2819	COG5012	cobalamin binding
Arad_2829	COG1410	methionine synthase
Arad_2829	COG0646	methionine synthase
Arad_2835	COG0583	DNA-binding transcription factor activity
Arad_2839	COG3706	GGDEF domain
Arad_2839	COG0745	RESPONSE REGULATOR receiver
Arad_2841	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Arad_2841	COG3264	Mechanosensitive ion channel
Arad_2848	COG1959	2 iron, 2 sulfur cluster binding
Arad_2852	COG0384	phenazine biosynthesis protein PhzF
Arad_2855	COG3842	ATPase activity
Arad_2859	COG0667	Aldo Keto reductase
Arad_2861	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arad_2863	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Arad_2866	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Arad_2868	COG2207	Transcriptional regulator
Arad_2869	COG1064	alcohol dehydrogenase
Arad_2870	COG1252	NADH dehydrogenase
Arad_2874	COG1522	sequence-specific DNA binding
Arad_2875	COG1794	racemase activity, acting on amino acids and derivatives
Arad_2878	COG0456	acetyltransferase
Arad_2880	COG2814	Major facilitator Superfamily
Arad_2881	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Arad_2882	COG1733	regulation of RNA biosynthetic process
Arad_2885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Arad_2887	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Arad_2894	COG0656	L-ascorbic acid biosynthetic process
Arad_2897	COG0440	acetolactate synthase activity
Arad_2898	COG0028	Belongs to the TPP enzyme family
Arad_2901	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Arad_2903	COG0560	Phosphoserine phosphatase
Arad_2903	COG3830	Belongs to the UPF0237 family
Arad_2906	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Arad_2909	COG0330	HflC and HflK could
Arad_2913	COG0463	Glycosyl transferase, family 2
Arad_2915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arad_2918	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Arad_2923	COG0410	ABC transporter
Arad_2926	COG0583	DNA-binding transcription factor activity
Arad_2930	COG3238	Protein conserved in bacteria
Arad_2934	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Arad_2940	COG0277	FAD linked oxidase domain protein
Arad_2941	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_2944	COG0765	amino acid transport
Arad_2950	COG2885	chlorophyll binding
Arad_2951	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Arad_2952	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arad_2954	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_2955	COG0210	DNA helicase
Arad_2959	COG1335	isochorismatase
Arad_2962	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Arad_2963	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Arad_2967	COG0006	proline dipeptidase activity
Arad_2968	COG2264	protein methyltransferase activity
Arad_2971	COG1999	signal sequence binding
Arad_2973	COG0835	chemotaxis
Arad_2979	COG1247	-acetyltransferase
Arad_2980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Arad_2982	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Arad_2986	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arad_2988	COG0849	cell division
Arad_2989	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Arad_2991	COG1181	Belongs to the D-alanine--D-alanine ligase family
Arad_2992	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Arad_2993	COG0477	Major facilitator Superfamily
Arad_2994	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Arad_2995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Arad_2996	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Arad_2998	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Arad_3000	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Arad_3002	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Arad_3005	COG2001	Belongs to the MraZ family
Arad_3006	COG0275	rRNA processing
Arad_3010	COG3023	N-Acetylmuramoyl-L-alanine amidase
Arad_3014	COG1280	lysine exporter protein (LysE YggA)
Arad_3021	COG4106	trans-aconitate 2-methyltransferase activity
Arad_3025	COG0697	spore germination
Arad_3028	COG2226	methyltransferase
Arad_3034	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Arad_3035	COG0028	Belongs to the TPP enzyme family
Arad_3036	COG0251	oxidation-reduction process
Arad_3040	COG1376	ErfK ybiS ycfS ynhG family protein
Arad_3042	COG1012	belongs to the aldehyde dehydrogenase family
Arad_3043	COG0174	glutamine synthetase
Arad_3051	COG2011	ABC-type metal ion transport system permease component
Arad_3052	COG3842	ATPase activity
Arad_3053	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Arad_3057	COG1609	Transcriptional regulator
Arad_3059	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Arad_3061	COG0673	inositol 2-dehydrogenase activity
Arad_3062	COG0395	ABC-type sugar transport system, permease component
Arad_3067	COG2971	BadF BadG BcrA BcrD
Arad_3071	COG4702	Belongs to the UPF0303 family
Arad_3088	COG2264	protein methyltransferase activity
Arad_3099	COG2968	Membrane
Arad_3103	COG0432	Pfam Uncharacterised protein family UPF0047
Arad_3104	COG5507	3-demethylubiquinone-9 3-methyltransferase
Arad_3110	COG0072	phenylalanine-tRNA ligase activity
Arad_3110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arad_3111	COG2207	Transcriptional regulator
Arad_3111	COG1917	Cupin 2, conserved barrel domain protein
Arad_3117	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Arad_3118	COG1063	alcohol dehydrogenase
Arad_3121	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_3122	COG0514	ATP-dependent DNA helicase (RecQ)
Arad_3123	COG0358	DNA primase activity
Arad_3127	COG0505	Belongs to the CarA family
Arad_3129	COG0534	Mate efflux family protein
Arad_3132	COG2321	neutral zinc metallopeptidase
Arad_3135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Arad_3136	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Arad_3141	COG1522	sequence-specific DNA binding
Arad_3143	COG0492	ferredoxin-NADP+ reductase activity
Arad_3145	COG0583	DNA-binding transcription factor activity
Arad_3148	COG1902	pentaerythritol trinitrate reductase activity
Arad_3151	COG0300	oxidoreductase activity
Arad_3152	COG0583	DNA-binding transcription factor activity
Arad_3154	COG0387	Pfam Sodium calcium exchanger
Arad_3158	COG2133	pyrroloquinoline quinone binding
Arad_3160	COG1278	Cold shock
Arad_3162	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arad_3167	COG1846	Transcriptional regulator
Arad_3169	COG0745	RESPONSE REGULATOR receiver
Arad_3170	COG2205	protein histidine kinase activity
Arad_3172	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Arad_3177	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Arad_3185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Arad_3189	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Arad_3192	COG0193	aminoacyl-tRNA hydrolase activity
Arad_3194	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Arad_3199	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Arad_3200	COG2857	Cytochrome c1
Arad_3200	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Arad_3205	COG1132	(ABC) transporter
Arad_3206	COG1132	(ABC) transporter
Arad_3207	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Arad_3212	COG0408	coproporphyrinogen oxidase activity
Arad_3216	COG0617	tRNA 3'-terminal CCA addition
Arad_3220	COG0714	Associated with various cellular activities
Arad_3226	COG0454	-acetyltransferase
Arad_3230	COG0435	Glutathione S-transferase
Arad_3241	COG1132	(ABC) transporter
Arad_3242	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arad_3243	COG3135	benzoate transporter
Arad_3244	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Arad_3246	COG0740	serine-type endopeptidase activity
Arad_3250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Arad_3251	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Arad_3252	COG0778	Nitroreductase
Arad_3255	COG0512	Glutamine amidotransferase of anthranilate synthase
Arad_3255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Arad_3256	COG0488	(ABC) transporter
Arad_3259	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Arad_3260	COG2862	Uncharacterized protein family, UPF0114
Arad_3263	COG2197	response regulator
Arad_3270	COG1435	thymidine kinase activity
Arad_3274	COG4176	ABC-type proline glycine betaine transport system permease component
Arad_3275	COG4175	Glycine betaine
Arad_3279	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Arad_3280	COG0366	Alpha amylase catalytic
Arad_3282	COG0601	transmembrane transport
Arad_3283	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_3285	COG4608	Belongs to the ABC transporter superfamily
Arad_3287	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_3290	COG1846	Transcriptional regulator
Arad_3291	COG1160	GTP binding
Arad_3297	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
Arad_3299	COG0024	Methionine aminopeptidase
Arad_3304	COG4941	Belongs to the sigma-70 factor family
Arad_3305	COG3795	YCII-related domain
Arad_3308	COG1619	proteins homologs of microcin C7 resistance protein MccF
Arad_3310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Arad_3311	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_3313	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Arad_3317	COG0583	DNA-binding transcription factor activity
Arad_3320	COG0402	S-adenosylhomocysteine deaminase activity
Arad_3321	COG1304	FMN binding
Arad_3324	COG2351	hydroxyisourate hydrolase activity
Arad_3326	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
Arad_3328	COG3195	allantoin biosynthetic process
Arad_3328	COG3648	Uricase
Arad_3331	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Arad_3332	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_3333	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Arad_3333	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_3335	COG5002	protein histidine kinase activity
Arad_3335	COG2205	protein histidine kinase activity
Arad_3335	COG0784	Response regulator, receiver
Arad_3336	COG5598	trimethylamine methyltransferase
Arad_3338	COG0513	Belongs to the DEAD box helicase family
Arad_3344	COG2308	Evidence 4 Homologs of previously reported genes of
Arad_3350	COG1132	(ABC) transporter
Arad_3352	COG1012	belongs to the aldehyde dehydrogenase family
Arad_3355	COG4214	carbohydrate transport
Arad_3362	COG0673	inositol 2-dehydrogenase activity
Arad_3364	COG4213	ABC transporter substrate-binding protein
Arad_3365	COG4214	carbohydrate transport
Arad_3366	COG1129	ABC transporter
Arad_3379	COG0671	phosphoesterase, PA-phosphatase related
Arad_3380	COG0745	RESPONSE REGULATOR receiver
Arad_3381	COG2194	sulfuric ester hydrolase activity
Arad_3385	COG0406	alpha-ribazole phosphatase activity
Arad_3395	COG0022	dehydrogenase e1 component
Arad_3398	COG0038	chloride channel
Arad_3403	COG2076	Multidrug Resistance protein
Arad_3405	COG3842	ATPase activity
Arad_3406	COG3833	ABC-type maltose transport systems, permease component
Arad_3413	COG0673	inositol 2-dehydrogenase activity
Arad_3414	COG1609	Transcriptional regulator
Arad_3427	COG4558	Periplasmic binding protein
Arad_3428	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arad_3429	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Arad_3436	COG0784	Response regulator, receiver
Arad_3438	COG2202	Pas domain
Arad_3438	COG3920	Histidine kinase
Arad_3439	COG0493	'glutamate synthase
Arad_3443	COG1309	transcriptional regulator
Arad_3452	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_3453	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_3455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_3457	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_3459	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Arad_3460	COG0830	nickel cation binding
Arad_3462	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Arad_3465	COG3706	GGDEF domain
Arad_3467	COG0804	urea catabolic process
Arad_3469	COG1442	glycosyl transferase family 8
Arad_3470	COG0832	Belongs to the urease beta subunit family
Arad_3472	COG0831	urea catabolic process
Arad_3474	COG0829	nickel cation binding
Arad_3476	COG0411	ABC transporter
Arad_3478	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_3481	COG0784	Response regulator, receiver
Arad_3481	COG2198	Histidine kinase
Arad_3481	COG5002	protein histidine kinase activity
Arad_3482	COG0745	RESPONSE REGULATOR receiver
Arad_3483	COG0683	leucine binding
Arad_3486	COG0411	ABC transporter
Arad_3493	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Arad_3493	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arad_3494	COG4311	Sarcosine oxidase, delta subunit
Arad_3496	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_3512	COG0564	pseudouridine synthase activity
Arad_3513	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Arad_3515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Arad_3518	COG0402	S-adenosylhomocysteine deaminase activity
Arad_3519	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Arad_3521	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arad_3522	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_3525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_3528	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_3529	COG0402	S-adenosylhomocysteine deaminase activity
Arad_3531	COG2249	NAD(P)H dehydrogenase (quinone) activity
Arad_3537	COG0346	lactoylglutathione lyase activity
Arad_3538	COG0251	oxidation-reduction process
Arad_3543	COG0346	lactoylglutathione lyase activity
Arad_3544	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Arad_3547	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Arad_3550	COG1349	DNA-binding transcription factor activity
Arad_3551	COG0583	DNA-binding transcription factor activity
Arad_3554	COG5001	Diguanylate cyclase
Arad_3554	COG3300	MHYT domain
Arad_3555	COG0129	dihydroxy-acid dehydratase activity
Arad_3557	COG2084	Dehydrogenase
Arad_3558	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arad_3562	COG0583	DNA-binding transcription factor activity
Arad_3564	COG1595	DNA-templated transcription, initiation
Arad_3567	COG0697	spore germination
Arad_3569	COG1846	Transcriptional regulator
Arad_3572	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Arad_3573	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_3575	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_3588	COG0477	Major facilitator Superfamily
Arad_3590	COG1278	Cold shock
Arad_3592	COG0346	lactoylglutathione lyase activity
Arad_3595	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_3604	COG2011	ABC-type metal ion transport system permease component
Arad_3606	COG4521	taurine ABC transporter
Arad_3608	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_3609	COG0330	HflC and HflK could
Arad_3610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_3613	COG2814	Major facilitator Superfamily
Arad_3647	COG0433	COG0433 Predicted ATPase
Arad_3657	COG0482	sulfurtransferase activity
Arad_3662	COG4589	Belongs to the CDS family
Arad_3664	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_3674	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Arad_3675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Arad_3676	COG0037	tRNA processing
Arad_3678	COG2885	chlorophyll binding
Arad_3679	COG0823	Involved in the tonB-independent uptake of proteins
Arad_3685	COG0824	Thioesterase
Arad_3688	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Arad_3689	COG1268	BioY protein
Arad_3690	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Arad_3692	COG2318	DinB family
Arad_3693	COG0494	nUDIX hydrolase
Arad_3694	COG1408	metallophosphoesterase
Arad_3695	COG2255	four-way junction helicase activity
Arad_3697	COG0632	four-way junction helicase activity
Arad_3699	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Arad_3701	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_3703	COG0217	transcriptional regulatory protein
Arad_3706	COG1692	metallophosphoesterase
Arad_3709	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arad_3719	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_3720	COG0300	oxidoreductase activity
Arad_3732	COG0126	phosphoglycerate kinase activity
Arad_3734	COG3588	fructose-bisphosphate aldolase
Arad_3737	COG0384	phenazine biosynthesis protein PhzF
Arad_3749	COG0254	rRNA binding
Arad_3751	COG3422	double-strand break repair
Arad_3759	COG0483	inositol monophosphate 1-phosphatase activity
Arad_3766	COG0640	Transcriptional regulator
Arad_3770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Arad_3771	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Arad_3772	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Arad_3773	COG0457	Tetratricopeptide repeat
Arad_3774	COG0596	Alpha beta hydrolase
Arad_3775	COG0583	DNA-binding transcription factor activity
Arad_3783	COG0469	pyruvate kinase activity
Arad_3789	COG3750	Belongs to the UPF0335 family
Arad_3798	COG2372	response to copper ion
Arad_3799	COG0726	polysaccharide deacetylase
Arad_3804	COG3108	Peptidase M15
Arad_3808	COG0512	Glutamine amidotransferase of anthranilate synthase
Arad_3808	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Arad_3814	COG5310	Homospermidine synthase
Arad_3820	COG0737	Belongs to the 5'-nucleotidase family
Arad_3821	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Arad_3822	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Arad_3825	COG0330	HflC and HflK could
Arad_3827	COG0517	IMP dehydrogenase activity
Arad_3827	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Arad_3829	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Arad_3830	COG2951	lytic endotransglycosylase activity
Arad_3836	COG0070	glutamate synthase
Arad_3836	COG0067	glutamate synthase
Arad_3836	COG0069	glutamate synthase activity
Arad_3843	COG0071	Belongs to the small heat shock protein (HSP20) family
Arad_3846	COG1522	sequence-specific DNA binding
Arad_3849	COG0454	-acetyltransferase
Arad_3850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Arad_3863	COG0662	Cupin 2, conserved barrel domain protein
Arad_3863	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Arad_3865	COG2308	Evidence 4 Homologs of previously reported genes of
Arad_3865	COG2307	Protein conserved in bacteria
Arad_3868	COG0058	SHG alpha-glucan phosphorylase activity
Arad_3869	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Arad_3871	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Arad_3872	COG0297	glycogen (starch) synthase activity
Arad_3873	COG0033	Phosphoglucomutase
Arad_3874	COG1523	belongs to the glycosyl hydrolase 13 family
Arad_3878	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arad_3878	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Arad_3882	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_3885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Arad_3890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_3891	COG2202	Pas domain
Arad_3891	COG3920	Histidine kinase
Arad_3892	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Arad_3893	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Arad_3894	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Arad_3896	COG5001	Diguanylate cyclase
Arad_3897	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Arad_3898	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Arad_3899	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Arad_3900	COG1609	Transcriptional regulator
Arad_3901	COG1846	Transcriptional regulator
Arad_3903	COG0523	cobalamin synthesis protein
Arad_3906	COG1045	serine acetyltransferase
Arad_3912	COG0583	DNA-binding transcription factor activity
Arad_3914	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Arad_3917	COG0800	Aldolase
Arad_3924	COG0431	NADPH-dependent FMN reductase
Arad_3928	COG0673	inositol 2-dehydrogenase activity
Arad_3932	COG1879	ABC-type sugar transport system periplasmic component
Arad_3934	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_3936	COG1609	Transcriptional regulator
Arad_3938	COG2115	Belongs to the xylose isomerase family
Arad_3939	COG1070	Carbohydrate kinase
Arad_3940	COG1609	Transcriptional regulator
Arad_3947	COG1253	flavin adenine dinucleotide binding
Arad_3953	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Arad_3954	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Arad_3957	COG0673	inositol 2-dehydrogenase activity
Arad_3958	COG1082	Xylose isomerase domain protein TIM barrel
Arad_3959	COG1082	Xylose isomerase domain protein TIM barrel
Arad_3964	COG0583	DNA-binding transcription factor activity
Arad_3966	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Arad_3969	COG3842	ATPase activity
Arad_3970	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_3972	COG1177	transmembrane transport
Arad_3980	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_3985	COG3254	rhamnose metabolic process
Arad_3986	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_3987	COG3842	ATPase activity
Arad_3988	COG0395	ABC-type sugar transport system, permease component
Arad_3990	COG1175	transmembrane transport
Arad_3999	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Arad_4003	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Arad_4010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arad_4014	COG0395	ABC-type sugar transport system, permease component
Arad_4016	COG1175	transmembrane transport
Arad_4019	COG2390	Transcriptional regulator
Arad_4021	COG4154	Belongs to the RbsD FucU family
Arad_4022	COG0745	RESPONSE REGULATOR receiver
Arad_4023	COG0642	Histidine kinase
Arad_4024	COG1940	carbohydrate kinase activity
Arad_4025	COG3142	Participates in the control of copper homeostasis
Arad_4029	COG2719	SpoVR family
Arad_4030	COG2718	Belongs to the UPF0229 family
Arad_4031	COG2766	serine protein kinase
Arad_4034	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Arad_4035	COG0424	maF-like protein
Arad_4037	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Arad_4039	COG5328	Belongs to the UPF0262 family
Arad_4040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Arad_4043	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Arad_4048	COG2514	catechol 2,3-dioxygenase activity
Arad_4050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Arad_4052	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_4057	COG1764	response to oxidative stress
Arad_4058	COG2186	Transcriptional regulator
Arad_4061	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_4062	COG0670	Belongs to the BI1 family
Arad_4066	COG3781	membrane
Arad_4067	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Arad_4068	COG2900	Belongs to the SlyX family
Arad_4070	COG3842	ATPase activity
Arad_4072	COG1175	transmembrane transport
Arad_4076	COG1609	Transcriptional regulator
Arad_4093	COG1396	sequence-specific DNA binding
Arad_4095	COG1396	sequence-specific DNA binding
Arad_4104	COG4467	Involved in initiation control of chromosome replication
Arad_4105	COG4372	Transposase
Arad_4117	COG4372	Transposase
Arad_4124	COG0542	response to heat
Arad_4127	COG2890	protein-(glutamine-N5) methyltransferase activity
Arad_4128	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Arad_4131	COG0527	aspartate kinase activity
Arad_4133	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Arad_4137	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Arad_4146	COG2226	methyltransferase
Arad_4152	COG0494	nUDIX hydrolase
Arad_4154	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Arad_4155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Arad_4157	COG0653	protein targeting
Arad_4159	COG0583	DNA-binding transcription factor activity
Arad_4160	COG1942	4-Oxalocrotonate Tautomerase
Arad_4161	COG0625	glutathione transferase activity
Arad_4164	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arad_4169	COG0681	Belongs to the peptidase S26 family
Arad_4170	COG0667	Aldo Keto reductase
Arad_4171	COG2264	protein methyltransferase activity
Arad_4184	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Arad_4186	COG1295	ribonuclease BN
Arad_4187	COG0300	oxidoreductase activity
Arad_4191	COG2086	electron transfer activity
Arad_4195	COG1250	3-hydroxyacyl-CoA dehydrogenase
Arad_4196	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Arad_4197	COG0165	Argininosuccinate lyase
Arad_4207	COG2884	Cell division ATP-binding protein ftsE
Arad_4212	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Arad_4216	COG0287	Prephenate dehydrogenase
Arad_4217	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Arad_4218	COG2226	methyltransferase
Arad_4219	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Arad_4221	COG2382	esterase
Arad_4224	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Arad_4233	COG4536	flavin adenine dinucleotide binding
Arad_4234	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Arad_4236	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Arad_4238	COG4974	Belongs to the 'phage' integrase family
Arad_4239	COG0825	malonyl-CoA metabolic process
Arad_4240	COG3034	peptidoglycan biosynthetic process
Arad_4243	COG0523	cobalamin synthesis protein
Arad_4244	COG1686	Belongs to the peptidase S11 family
Arad_4246	COG1473	amidohydrolase
Arad_4263	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Arad_4265	COG0156	8-amino-7-oxononanoate synthase activity
Arad_4270	COG0729	surface antigen
Arad_4277	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arad_4278	COG0835	chemotaxis
Arad_4284	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Arad_4285	COG3383	formate dehydrogenase (NAD+) activity
Arad_4290	COG0640	Transcriptional regulator
Arad_4299	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_4300	COG1012	belongs to the aldehyde dehydrogenase family
Arad_4301	COG1454	alcohol dehydrogenase
Arad_4304	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Arad_4306	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Arad_4307	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Arad_4308	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Arad_4310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Arad_4319	COG4974	Belongs to the 'phage' integrase family
Arad_4323	COG0612	Peptidase, M16
Arad_4326	COG1280	lysine exporter protein (LysE YggA)
Arad_4327	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_4330	COG0508	dehydrogenase complex catalyzes the overall conversion of
Arad_4333	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Arad_4336	COG0045	succinate-CoA ligase (ADP-forming) activity
Arad_4338	COG0039	L-malate dehydrogenase activity
Arad_4339	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Arad_4341	COG3541	Predicted nucleotidyltransferase
Arad_4350	COG2264	protein methyltransferase activity
Arad_4352	COG2350	Protein conserved in bacteria
Arad_4354	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Arad_4355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Arad_4356	COG0181	hydroxymethylbilane synthase activity
Arad_4365	COG1872	DUF167
Arad_4366	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Arad_4371	COG0339	signal peptide processing
Arad_4374	COG0137	argininosuccinate synthase activity
Arad_4376	COG1280	lysine exporter protein (LysE YggA)
Arad_4378	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Arad_4381	COG2154	pterin-4-alpha-carbinolamine dehydratase
Arad_4382	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Arad_4383	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Arad_4385	COG4181	ATPase activity
Arad_4388	COG0670	Belongs to the BI1 family
Arad_4394	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Arad_4395	COG4133	protoheme IX ABC transporter activity
Arad_4396	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Arad_4397	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Arad_4402	COG2917	probably involved in intracellular septation
Arad_4403	COG0552	protein localization to endoplasmic reticulum
Arad_4404	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Arad_4405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Arad_4410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Arad_4411	COG1605	Chorismate mutase
Arad_4411	COG0287	Prephenate dehydrogenase
Arad_4412	COG0228	four-way junction DNA binding
Arad_4414	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Arad_4416	COG0336	Belongs to the RNA methyltransferase TrmD family
Arad_4424	COG1522	sequence-specific DNA binding
Arad_4427	COG0110	maltose O-acetyltransferase activity
Arad_4428	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Arad_4429	COG0335	large ribosomal subunit rRNA binding
Arad_4432	COG0765	amino acid transport
Arad_4434	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Arad_4435	COG0697	spore germination
Arad_4437	COG1846	Transcriptional regulator
Arad_4442	COG0656	L-ascorbic acid biosynthetic process
Arad_4444	COG0745	RESPONSE REGULATOR receiver
Arad_4448	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Arad_4449	COG1674	ftsk spoiiie
Arad_4451	COG0004	ammonium transporteR
Arad_4452	COG0347	Belongs to the P(II) protein family
Arad_4453	COG1946	Acyl-CoA thioesterase
Arad_4454	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Arad_4455	COG1733	regulation of RNA biosynthetic process
Arad_4457	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_4458	COG2835	tetraacyldisaccharide 4'-kinase activity
Arad_4460	COG3118	belongs to the thioredoxin family
Arad_4469	COG1609	Transcriptional regulator
Arad_4474	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_4475	COG0745	RESPONSE REGULATOR receiver
Arad_4476	COG2205	protein histidine kinase activity
Arad_4488	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Arad_4490	COG2076	Multidrug Resistance protein
Arad_4493	COG1647	Serine aminopeptidase, S33
Arad_4497	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Arad_4499	COG0642	Histidine kinase
Arad_4501	COG0745	RESPONSE REGULATOR receiver
Arad_4502	COG3618	amidohydrolase
Arad_4505	COG2188	Transcriptional regulator
Arad_4508	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arad_4509	COG0697	spore germination
Arad_4512	COG1309	transcriptional regulator
Arad_4515	COG0596	Alpha beta hydrolase
Arad_4516	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Arad_4519	COG0438	transferase activity, transferring glycosyl groups
Arad_4526	COG0642	Histidine kinase
Arad_4530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_4531	COG1116	anion transmembrane transporter activity
Arad_4532	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_4535	COG1396	sequence-specific DNA binding
Arad_4545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_4546	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arad_4548	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arad_4559	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Arad_4562	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Arad_4563	COG2986	histidine ammonia-lyase
Arad_4564	COG1228	amidohydrolase
Arad_4566	COG2188	Transcriptional regulator
Arad_4568	COG2986	histidine ammonia-lyase
Arad_4571	COG0025	NhaP-type Na H and K H
Arad_4577	COG1321	iron dependent repressor
Arad_4578	COG1914	H( )-stimulated, divalent metal cation uptake system
Arad_4580	COG0739	heme binding
Arad_4584	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Arad_4585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Arad_4586	COG2080	2 iron, 2 sulfur cluster binding
Arad_4588	COG1309	transcriptional regulator
Arad_4590	COG3842	ATPase activity
Arad_4592	COG0395	ABC-type sugar transport system, permease component
Arad_4593	COG1175	transmembrane transport
Arad_4605	COG3842	ATPase activity
Arad_4608	COG0395	ABC-type sugar transport system, permease component
Arad_4611	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
Arad_4612	COG2182	Extracellular solute-binding protein
Arad_4616	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_4618	COG0673	inositol 2-dehydrogenase activity
Arad_4620	COG0673	inositol 2-dehydrogenase activity
Arad_4621	COG1309	transcriptional regulator
Arad_4624	COG1175	transmembrane transport
Arad_4625	COG0395	ABC-type sugar transport system, permease component
Arad_4627	COG0673	inositol 2-dehydrogenase activity
Arad_4629	COG0673	inositol 2-dehydrogenase activity
Arad_4630	COG3842	ATPase activity
Arad_4633	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Arad_4636	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Arad_4637	COG1509	lysine 2,3-aminomutase activity
Arad_4638	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Arad_4639	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Arad_4643	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Arad_4651	COG2188	Transcriptional regulator
Arad_4652	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Arad_4653	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Arad_4656	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_4662	COG0477	Major facilitator Superfamily
Arad_4665	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Arad_4667	COG4783	chaperone-mediated protein folding
Arad_4669	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Arad_4671	COG1329	Transcriptional regulator
Arad_4682	COG0183	Belongs to the thiolase family
Arad_4683	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Arad_4685	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Arad_4689	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Arad_4690	COG0142	geranyltranstransferase activity
Arad_4692	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Arad_4693	COG2223	nitrite transmembrane transporter activity
Arad_4694	COG0697	spore germination
Arad_4700	COG0662	Cupin 2, conserved barrel domain protein
Arad_4704	COG0740	serine-type endopeptidase activity
Arad_4705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_4707	COG0765	amino acid transport
Arad_4709	COG1126	abc transporter atp-binding protein
Arad_4713	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_4714	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
Arad_4718	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Arad_4720	COG1132	(ABC) transporter
Arad_4726	COG3459	Glycosyltransferase 36 associated
Arad_4734	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_4735	COG0601	transmembrane transport
Arad_4739	COG1280	lysine exporter protein (LysE YggA)
Arad_4741	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
Arad_4742	COG3316	Transposase and inactivated derivatives
Arad_4761	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_4762	COG1129	ABC transporter
Arad_4775	COG3038	cytochrome b561
Arad_4778	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Arad_4780	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
Arad_4781	COG2948	multi-organism process
Arad_4783	COG3736	Type IV secretory pathway, component VirB8
Arad_4784	COG3504	Conjugal transfer protein
Arad_4786	COG3704	protein secretion by the type IV secretion system
Arad_4789	COG3451	type IV secretory pathway VirB4
Arad_4790	COG3838	Conjugal transfer protein Trbc
Arad_4792	COG3702	type iv secretory pathway
Arad_4803	COG1396	sequence-specific DNA binding
Arad_4804	COG1476	TRANSCRIPTIONal
Arad_4814	COG3505	Type IV secretory pathway VirD4
Arad_4820	COG3436	PFAM IS66 Orf2 family protein
Arad_4821	COG4372	Transposase
Arad_4824	COG3436	PFAM IS66 Orf2 family protein
Arad_4825	COG2963	transposase activity
Arad_4830	COG1216	Glycosyl transferase, family 2
Arad_4830	COG0438	transferase activity, transferring glycosyl groups
Arad_4837	COG1088	dTDP-glucose 4,6-dehydratase activity
Arad_4838	COG1091	dTDP-4-dehydrorhamnose reductase activity
Arad_4847	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Arad_4848	COG0438	transferase activity, transferring glycosyl groups
Arad_4857	COG3220	belongs to the UPF0276 family
Arad_4869	COG4650	regulator
Arad_4870	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Arad_4872	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Arad_4875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arad_4877	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Arad_4878	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Arad_4880	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Arad_4883	COG0725	ABC transporter, periplasmic molybdate-binding protein
Arad_4884	COG4149	molybdate abc transporter
Arad_4885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Arad_4886	COG2005	Transcriptional regulator
Arad_4886	COG3585	molybdate ion transport
Arad_4887	COG0799	negative regulation of ribosome biogenesis
Arad_4889	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Arad_4892	COG0793	Belongs to the peptidase S41A family
Arad_4894	COG0494	nUDIX hydrolase
Arad_4897	COG0587	DNA-directed DNA polymerase activity
Arad_4898	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Arad_4903	COG2301	Belongs to the HpcH HpaI aldolase family
Arad_4906	COG0066	3-isopropylmalate dehydratase activity
Arad_4909	COG0473	3-isopropylmalate dehydrogenase activity
Arad_4910	COG0671	phosphoesterase, PA-phosphatase related
Arad_4914	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_4916	COG0783	Belongs to the Dps family
Arad_4918	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Arad_4922	COG0288	reversible hydration of carbon dioxide
Arad_4924	COG2902	Dehydrogenase
Arad_4925	COG2270	Major facilitator Superfamily
Arad_4926	COG0138	bifunctional purine biosynthesis protein purh
Arad_4928	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Arad_4928	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Arad_4929	COG0501	Belongs to the peptidase M48B family
Arad_4932	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Arad_4935	COG0495	leucyl-tRNA aminoacylation
Arad_4938	COG1475	DNA binding
Arad_4939	COG1192	Involved in chromosome partitioning
Arad_4940	COG0357	Ribosomal RNA small subunit methyltransferase G
Arad_4941	COG0445	tRNA wobble uridine modification
Arad_4943	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Arad_4944	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Arad_4947	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Arad_4980	COG0424	maF-like protein
Arad_4984	COG1476	TRANSCRIPTIONal
Arad_4987	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Arad_4988	COG0328	RNA-DNA hybrid ribonuclease activity
Arad_4989	COG1121	(ABC) transporter
Arad_7000	COG1192	Involved in chromosome partitioning
Arad_7001	COG1475	DNA binding
Arad_7003	COG1414	Transcriptional regulator
Arad_7006	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_7008	COG0583	DNA-binding transcription factor activity
Arad_7020	COG0745	RESPONSE REGULATOR receiver
Arad_7021	COG2205	protein histidine kinase activity
Arad_7022	COG1012	belongs to the aldehyde dehydrogenase family
Arad_7023	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_7028	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_7039	COG1012	belongs to the aldehyde dehydrogenase family
Arad_7041	COG0840	transmembrane signaling receptor activity
Arad_7044	COG1902	pentaerythritol trinitrate reductase activity
Arad_7046	COG0427	acetyl-CoA hydrolase
Arad_7047	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_7049	COG4208	sulfate ABC transporter
Arad_7050	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_7052	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_7056	COG0583	DNA-binding transcription factor activity
Arad_7058	COG1126	abc transporter atp-binding protein
Arad_7060	COG0765	amino acid transport
Arad_7061	COG0765	amino acid transport
Arad_7065	COG0667	Aldo Keto reductase
Arad_7066	COG0583	DNA-binding transcription factor activity
Arad_7069	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_7070	COG2267	carboxylic ester hydrolase activity
Arad_7071	COG0251	oxidation-reduction process
Arad_7072	COG1335	isochorismatase
Arad_7073	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_7074	COG5265	(ABC) transporter
Arad_7078	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7079	COG1846	Transcriptional regulator
Arad_7079	COG1940	carbohydrate kinase activity
Arad_7080	COG1082	Xylose isomerase domain protein TIM barrel
Arad_7081	COG2207	Transcriptional regulator
Arad_7081	COG1917	Cupin 2, conserved barrel domain protein
Arad_7083	COG1175	transmembrane transport
Arad_7087	COG1063	alcohol dehydrogenase
Arad_7088	COG3842	ATPase activity
Arad_7089	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7096	COG0006	proline dipeptidase activity
Arad_7097	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_7098	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arad_7100	COG1126	abc transporter atp-binding protein
Arad_7102	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_7104	COG2186	Transcriptional regulator
Arad_7105	COG1177	transmembrane transport
Arad_7107	COG3842	ATPase activity
Arad_7111	COG1024	Enoyl-CoA hydratase
Arad_7114	COG0277	FAD linked oxidase domain protein
Arad_7116	COG0604	alcohol dehydrogenase
Arad_7117	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
Arad_7118	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_7123	COG1802	Transcriptional regulator
Arad_7124	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_7125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_7129	COG0765	amino acid transport
Arad_7130	COG0765	amino acid transport
Arad_7135	COG0444	Belongs to the ABC transporter superfamily
Arad_7137	COG4608	Belongs to the ABC transporter superfamily
Arad_7138	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_7141	COG0747	negative chemotaxis
Arad_7142	COG3257	ureidoglycine aminohydrolase activity
Arad_7145	COG4993	Dehydrogenase
Arad_7147	COG0583	DNA-binding transcription factor activity
Arad_7152	COG0840	transmembrane signaling receptor activity
Arad_7154	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Arad_7159	COG3485	protocatechuate 3,4-dioxygenase
Arad_7162	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_7164	COG2814	Major facilitator Superfamily
Arad_7171	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_7177	COG0835	chemotaxis
Arad_7179	COG3316	Transposase and inactivated derivatives
Arad_7181	COG4566	intracellular signal transduction
Arad_7182	COG4191	Histidine kinase
Arad_7183	COG2140	Oxalate decarboxylase
Arad_7194	COG5001	Diguanylate cyclase
Arad_7209	COG2084	Dehydrogenase
Arad_7211	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7212	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_7214	COG1129	ABC transporter
Arad_7223	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_7227	COG0235	Class ii aldolase
Arad_7229	COG2423	ornithine cyclodeaminase activity
Arad_7232	COG0477	Major facilitator Superfamily
Arad_7233	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arad_7236	COG0583	DNA-binding transcription factor activity
Arad_7238	COG2814	Major facilitator Superfamily
Arad_7240	COG0583	DNA-binding transcription factor activity
Arad_7251	COG1335	isochorismatase
Arad_7254	COG1802	Transcriptional regulator
Arad_7255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arad_7256	COG4569	acetaldehyde dehydrogenase (acetylating) activity
Arad_7257	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Arad_7261	COG0179	Fumarylacetoacetate (FAA) hydrolase
Arad_7264	COG3971	2-oxopent-4-enoate hydratase activity
Arad_7279	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7280	COG0583	DNA-binding transcription factor activity
Arad_7281	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7285	COG1335	isochorismatase
Arad_7286	COG0583	DNA-binding transcription factor activity
Arad_7287	COG0583	DNA-binding transcription factor activity
Arad_7291	COG0697	spore germination
Arad_7296	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_7297	COG0683	leucine binding
Arad_7301	COG0411	ABC transporter
Arad_7304	COG1802	Transcriptional regulator
Arad_7310	COG0765	amino acid transport
Arad_7314	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_7317	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7318	COG2197	response regulator
Arad_7319	COG0601	transmembrane transport
Arad_7326	COG0747	negative chemotaxis
Arad_7332	COG4191	Histidine kinase
Arad_7332	COG0784	Response regulator, receiver
Arad_7333	COG2197	response regulator
Arad_7336	COG3920	Histidine kinase
Arad_7339	COG0753	catalase activity
Arad_7343	COG0765	amino acid transport
Arad_7345	COG0765	amino acid transport
Arad_7346	COG4598	ABC transporter
Arad_7354	COG0793	Belongs to the peptidase S41A family
Arad_7355	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7357	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arad_7359	COG4149	molybdate abc transporter
Arad_7360	COG3842	ATPase activity
Arad_7363	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_7364	COG0583	DNA-binding transcription factor activity
Arad_7376	COG0583	DNA-binding transcription factor activity
Arad_7378	COG0583	DNA-binding transcription factor activity
Arad_7379	COG3384	dioxygenase
Arad_7383	COG0025	NhaP-type Na H and K H
Arad_7387	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_7388	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arad_7389	COG0745	RESPONSE REGULATOR receiver
Arad_7393	COG2022	thiamine diphosphate biosynthetic process
Arad_7398	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Arad_7399	COG1609	Transcriptional regulator
Arad_7401	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_7405	COG0765	amino acid transport
Arad_7407	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Arad_7410	COG0583	DNA-binding transcription factor activity
Arad_7414	COG0765	amino acid transport
Arad_7416	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_7417	COG1522	sequence-specific DNA binding
Arad_7422	COG0667	Aldo Keto reductase
Arad_7425	COG2814	Major facilitator Superfamily
Arad_7428	COG0583	DNA-binding transcription factor activity
Arad_7431	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Arad_7432	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Arad_7433	COG2080	2 iron, 2 sulfur cluster binding
Arad_7434	COG2814	Major facilitator Superfamily
Arad_7447	COG3153	acetyltransferase
Arad_7453	COG0698	ribose 5-phosphate isomerase
Arad_7454	COG0149	triose-phosphate isomerase activity
Arad_7464	COG1129	ABC transporter
Arad_7465	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_7467	COG1879	ABC-type sugar transport system periplasmic component
Arad_7468	COG1349	DNA-binding transcription factor activity
Arad_7469	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Arad_7470	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Arad_7473	COG0511	ligase activity, forming carbon-carbon bonds
Arad_7474	COG0439	Biotin carboxylase
Arad_7478	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_7479	COG1984	allophanate hydrolase subunit 2
Arad_7480	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_7485	COG4221	oxidoreductase activity
Arad_7487	COG0765	amino acid transport
Arad_7488	COG0765	amino acid transport
Arad_7492	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arad_7494	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_7503	COG3842	ATPase activity
Arad_7504	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_7509	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7512	COG3842	ATPase activity
Arad_7513	COG0726	polysaccharide deacetylase
Arad_7516	COG0523	cobalamin synthesis protein
Arad_7518	COG0154	amidase activity
Arad_7520	COG2909	trisaccharide binding
Arad_7523	COG3842	ATPase activity
Arad_7525	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_7526	COG1177	transmembrane transport
Arad_7527	COG1129	ABC transporter
Arad_7529	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_7530	COG1879	ABC-type sugar transport system periplasmic component
Arad_7532	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7533	COG2376	Dihydroxyacetone kinase
Arad_7536	COG2376	Dihydroxyacetone kinase
Arad_7541	COG2207	Transcriptional regulator
Arad_7542	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7544	COG1335	isochorismatase
Arad_7546	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_7566	COG1012	belongs to the aldehyde dehydrogenase family
Arad_7568	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Arad_7571	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Arad_7576	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Arad_7578	COG4191	Histidine kinase
Arad_7578	COG0784	Response regulator, receiver
Arad_7580	COG1294	oxidase, subunit
Arad_7581	COG1271	oxidase subunit
Arad_7582	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Arad_7583	COG4988	ABC transporter
Arad_7586	COG0516	GMP reductase activity
Arad_7586	COG0517	IMP dehydrogenase activity
Arad_7597	COG3609	addiction module antidote protein, CC2985 family
Arad_7598	COG3668	Plasmid stabilization system
Arad_7607	COG2208	phosphoserine phosphatase activity
Arad_7608	COG2226	methyltransferase
Arad_7610	COG3300	MHYT domain
Arad_7610	COG5001	Diguanylate cyclase
Arad_7614	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Arad_7616	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Arad_7621	COG4372	Transposase
Arad_7623	COG2273	Hydrolase Family 16
Arad_7623	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Arad_7628	COG2197	response regulator
Arad_7630	COG2890	protein-(glutamine-N5) methyltransferase activity
Arad_7631	COG0367	asparagine synthase
Arad_7633	COG0318	PFAM AMP-dependent synthetase and ligase
Arad_7634	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Arad_7635	COG3321	synthase
Arad_7635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Arad_7635	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Arad_7635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Arad_7637	COG3300	MHYT domain
Arad_7637	COG5001	Diguanylate cyclase
Arad_7639	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Arad_7646	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_7647	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_7648	COG1116	anion transmembrane transporter activity
Arad_7649	COG4191	Histidine kinase
Arad_7651	COG1609	Transcriptional regulator
Arad_7652	COG2271	Major facilitator Superfamily
Arad_7653	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_7654	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_7666	COG4774	siderophore transport
Arad_7667	COG2814	Major facilitator Superfamily
Arad_7670	COG1473	amidohydrolase
Arad_7676	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_7686	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_7690	COG0667	Aldo Keto reductase
Arad_7697	COG0747	negative chemotaxis
Arad_7699	COG0583	DNA-binding transcription factor activity
Arad_7700	COG0778	Nitroreductase
Arad_7708	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_7710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_7711	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_7712	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_7713	COG0454	-acetyltransferase
Arad_7715	COG0747	negative chemotaxis
Arad_7716	COG0747	negative chemotaxis
Arad_7718	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_7719	COG4172	Belongs to the ABC transporter superfamily
Arad_7721	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_7736	COG1653	transport
Arad_7738	COG2188	Transcriptional regulator
Arad_7742	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_7743	COG0601	transmembrane transport
Arad_7744	COG0747	negative chemotaxis
Arad_7745	COG2186	Transcriptional regulator
Arad_7746	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_7748	COG0747	negative chemotaxis
Arad_7749	COG0601	transmembrane transport
Arad_7751	COG0444	Belongs to the ABC transporter superfamily
Arad_7752	COG4608	Belongs to the ABC transporter superfamily
Arad_7753	COG0483	inositol monophosphate 1-phosphatase activity
Arad_7754	COG0584	glycerophosphoryl diester phosphodiesterase
Arad_7755	COG1940	carbohydrate kinase activity
Arad_7756	COG3300	MHYT domain
Arad_7756	COG5001	Diguanylate cyclase
Arad_7760	COG2226	methyltransferase
Arad_7761	COG3755	Protein conserved in bacteria
Arad_7766	COG0840	transmembrane signaling receptor activity
Arad_7768	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_7769	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_7770	COG1129	ABC transporter
Arad_7774	COG0477	Major facilitator Superfamily
Arad_7775	COG1309	transcriptional regulator
Arad_7777	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Arad_7783	COG1396	sequence-specific DNA binding
Arad_7787	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Arad_7791	COG0840	transmembrane signaling receptor activity
Arad_7796	COG3177	Filamentation induced by cAMP protein fic
Arad_7809	COG0668	transmembrane transport
Arad_7818	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Arad_7824	COG0714	Associated with various cellular activities
Arad_7826	COG3119	arylsulfatase activity
Arad_7831	COG2124	cytochrome p450
Arad_7833	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Arad_7837	COG0542	response to heat
Arad_7845	COG4195	phage-related replication protein
Arad_7854	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Arad_7857	COG3639	organic phosphonate transmembrane transporter activity
Arad_7867	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Arad_7868	COG0028	Belongs to the TPP enzyme family
Arad_7868	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
Arad_7872	COG0431	NADPH-dependent FMN reductase
Arad_7877	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Arad_7879	COG3475	LICD family
Arad_7889	COG3344	reverse transcriptase
Arad_7890	COG0667	Aldo Keto reductase
Arad_7897	COG0300	oxidoreductase activity
Arad_7906	COG3781	membrane
Arad_7907	COG0243	molybdopterin cofactor binding
Arad_7908	COG1271	oxidase subunit
Arad_7909	COG1294	oxidase, subunit
Arad_7914	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Arad_7915	COG0668	transmembrane transport
Arad_7917	COG0303	'Molybdopterin
Arad_7918	COG0443	Heat shock 70 kDa protein
Arad_7920	COG0484	heat shock protein binding
Arad_7924	COG4191	Histidine kinase
Arad_7925	COG0542	response to heat
Arad_7929	COG2837	iron assimilation
Arad_7932	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Arad_7933	COG0028	Belongs to the TPP enzyme family
Arad_7939	COG0747	negative chemotaxis
Arad_7940	COG0601	transmembrane transport
Arad_7942	COG3964	amidohydrolase
Arad_7947	COG1921	L-seryl-tRNASec selenium transferase activity
Arad_7949	COG0765	amino acid transport
Arad_7951	COG0765	amino acid transport
Arad_7952	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_7953	COG1126	abc transporter atp-binding protein
Arad_7954	COG2072	flavoprotein involved in K transport
Arad_7962	COG0765	amino acid transport
Arad_7963	COG0765	amino acid transport
Arad_7966	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_7968	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_7969	COG1984	allophanate hydrolase subunit 2
Arad_7971	COG1802	Transcriptional regulator
Arad_7975	COG0006	proline dipeptidase activity
Arad_7985	COG3932	Exopolysaccharide synthesis, ExoD
Arad_7988	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_7998	COG4957	zinc ion binding
Arad_8002	COG4797	methyltransferase
Arad_8002	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Arad_8005	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Arad_8007	COG0583	DNA-binding transcription factor activity
Arad_8009	COG0583	DNA-binding transcription factor activity
Arad_8010	COG0477	Major facilitator Superfamily
Arad_8015	COG0601	transmembrane transport
Arad_8016	COG0747	negative chemotaxis
Arad_8020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Arad_8023	COG1129	ABC transporter
Arad_8026	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Arad_8027	COG0583	DNA-binding transcription factor activity
Arad_8030	COG4608	Belongs to the ABC transporter superfamily
Arad_8032	COG0402	S-adenosylhomocysteine deaminase activity
Arad_8036	COG0747	negative chemotaxis
Arad_8037	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Arad_8040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Arad_8046	COG4774	siderophore transport
Arad_8052	COG3842	ATPase activity
Arad_8053	COG0395	ABC-type sugar transport system, permease component
Arad_8054	COG1175	transmembrane transport
Arad_8064	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Arad_8069	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Arad_8072	COG2144	transferase activity, transferring acyl groups
Arad_8074	COG0438	transferase activity, transferring glycosyl groups
Arad_8080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_8081	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_8083	COG0659	secondary active sulfate transmembrane transporter activity
Arad_8094	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_8112	COG0640	Transcriptional regulator
Arad_8116	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_8117	COG1116	anion transmembrane transporter activity
Arad_8124	COG2186	Transcriptional regulator
Arad_8125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arad_8126	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8127	COG3842	ATPase activity
Arad_8128	COG1653	transport
Arad_8130	COG1175	transmembrane transport
Arad_8133	COG0395	ABC-type sugar transport system, permease component
Arad_8134	COG0840	transmembrane signaling receptor activity
Arad_8140	COG1802	Transcriptional regulator
Arad_8142	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_8144	COG1012	belongs to the aldehyde dehydrogenase family
Arad_8147	COG3448	diguanylate cyclase activity
Arad_8147	COG4175	Glycine betaine
Arad_8148	COG4176	ABC-type proline glycine betaine transport system permease component
Arad_8150	COG4176	ABC-type proline glycine betaine transport system permease component
Arad_8151	COG3938	Belongs to the proline racemase family
Arad_8153	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_8159	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_8165	COG2130	NADP-dependent
Arad_8173	COG1082	Xylose isomerase domain protein TIM barrel
Arad_8174	COG0673	inositol 2-dehydrogenase activity
Arad_8176	COG1082	Xylose isomerase domain protein TIM barrel
Arad_8177	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8178	COG0149	triose-phosphate isomerase activity
Arad_8179	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8180	COG1129	ABC transporter
Arad_8181	COG1879	ABC-type sugar transport system periplasmic component
Arad_8182	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_8183	COG3959	Transketolase, thiamine diphosphate binding domain
Arad_8184	COG3958	Transketolase
Arad_8185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Arad_8186	COG2390	Transcriptional regulator
Arad_8188	COG0673	inositol 2-dehydrogenase activity
Arad_8193	COG1063	alcohol dehydrogenase
Arad_8194	COG1609	Transcriptional regulator
Arad_8196	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Arad_8198	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Arad_8200	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Arad_8201	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Arad_8204	COG0840	transmembrane signaling receptor activity
Arad_8208	COG1522	sequence-specific DNA binding
Arad_8212	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Arad_8214	COG0625	glutathione transferase activity
Arad_8216	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Arad_8218	COG2819	hydrolase of the alpha beta superfamily
Arad_8219	COG4774	siderophore transport
Arad_8225	COG1120	ATPase activity
Arad_8230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Arad_8233	COG0626	cystathionine gamma-synthase activity
Arad_8234	COG0019	diaminopimelate decarboxylase activity
Arad_8240	COG3842	ATPase activity
Arad_8241	COG1396	sequence-specific DNA binding
Arad_8245	COG1177	transmembrane transport
Arad_8246	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_8248	COG0671	phosphoesterase, PA-phosphatase related
Arad_8252	COG1780	Probably involved in ribonucleotide reductase function
Arad_8253	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Arad_8257	COG4566	intracellular signal transduction
Arad_8258	COG4191	Histidine kinase
Arad_8259	COG1116	anion transmembrane transporter activity
Arad_8265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_8266	COG0601	transmembrane transport
Arad_8269	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arad_8272	COG0411	ABC transporter
Arad_8276	COG1846	Transcriptional regulator
Arad_8286	COG1846	Transcriptional regulator
Arad_8291	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Arad_8291	COG2010	Cytochrome c
Arad_8292	COG2080	2 iron, 2 sulfur cluster binding
Arad_8298	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_8299	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_8300	COG0411	ABC transporter
Arad_8305	COG1012	belongs to the aldehyde dehydrogenase family
Arad_8309	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_8310	COG1309	transcriptional regulator
Arad_8314	COG1175	transmembrane transport
Arad_8316	COG0395	ABC-type sugar transport system, permease component
Arad_8326	COG3842	ATPase activity
Arad_8330	COG1082	Xylose isomerase domain protein TIM barrel
Arad_8335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_8336	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Arad_8338	COG1522	sequence-specific DNA binding
Arad_8347	COG0463	Glycosyl transferase, family 2
Arad_8348	COG0803	Belongs to the bacterial solute-binding protein 9 family
Arad_8350	COG1121	(ABC) transporter
Arad_8351	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Arad_8352	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Arad_8356	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Arad_8356	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arad_8357	COG4311	Sarcosine oxidase, delta subunit
Arad_8358	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_8359	COG4977	sequence-specific DNA binding
Arad_8362	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Arad_8364	COG2218	PFAM glutamate synthase alpha subunit domain protein
Arad_8365	COG0069	glutamate synthase activity
Arad_8371	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Arad_8372	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Arad_8378	COG0840	transmembrane signaling receptor activity
Arad_8379	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Arad_8387	COG1174	glycine betaine transport
Arad_8392	COG1732	Glycine betaine
Arad_8393	COG2986	histidine ammonia-lyase
Arad_8403	COG2986	histidine ammonia-lyase
Arad_8407	COG1024	Enoyl-CoA hydratase
Arad_8409	COG1396	sequence-specific DNA binding
Arad_8411	COG2721	sulfolactate sulfo-lyase activity
Arad_8412	COG1063	alcohol dehydrogenase
Arad_8413	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Arad_8414	COG1126	abc transporter atp-binding protein
Arad_8415	COG0765	amino acid transport
Arad_8417	COG0246	Mannitol dehydrogenase
Arad_8418	COG1802	Transcriptional regulator
Arad_8419	COG3386	PFAM SMP-30 Gluconolaconase
Arad_8422	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_8423	COG1129	ABC transporter
Arad_8425	COG1879	ABC-type sugar transport system periplasmic component
Arad_8426	COG4585	Histidine kinase
Arad_8429	COG2224	Isocitrate lyase
Arad_8434	COG3743	rRNA binding
Arad_8434	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Arad_8437	COG4172	Belongs to the ABC transporter superfamily
Arad_8438	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_8441	COG2267	carboxylic ester hydrolase activity
Arad_8442	COG2197	response regulator
Arad_8448	COG0583	DNA-binding transcription factor activity
Arad_8449	COG3634	alkyl hydroperoxide reductase activity
Arad_8451	COG0450	alkyl hydroperoxide reductase
Arad_8459	COG2169	Transcriptional regulator
Arad_8461	COG2223	nitrite transmembrane transporter activity
Arad_8470	COG1032	radical SAM domain protein
Arad_8472	COG1132	(ABC) transporter
Arad_8478	COG0583	DNA-binding transcription factor activity
Arad_8479	COG2814	Major facilitator Superfamily
Arad_8481	COG0656	L-ascorbic acid biosynthetic process
Arad_8482	COG3459	Glycosyltransferase 36 associated
Arad_8483	COG3250	beta-galactosidase activity
Arad_8485	COG1312	Catalyzes the dehydration of D-mannonate
Arad_8490	COG5001	Diguanylate cyclase
Arad_8496	COG4120	Belongs to the binding-protein-dependent transport system permease family
Arad_8497	COG1122	ATPase activity
Arad_8500	COG1802	Transcriptional regulator
Arad_8503	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_8513	COG2353	YceI-like domain
Arad_8519	COG0583	DNA-binding transcription factor activity
Arad_8520	COG2828	Protein conserved in bacteria
Arad_8521	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_8523	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_8526	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_8529	COG1609	Transcriptional regulator
Arad_8534	COG0673	inositol 2-dehydrogenase activity
Arad_8539	COG1733	regulation of RNA biosynthetic process
Arad_8540	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_8541	COG1301	dicarboxylic acid transport
Arad_8542	COG0583	DNA-binding transcription factor activity
Arad_8544	COG4221	oxidoreductase activity
Arad_8545	COG1764	response to oxidative stress
Arad_8548	COG1396	sequence-specific DNA binding
Arad_8553	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arad_8554	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Arad_8555	COG1309	transcriptional regulator
Arad_8560	COG0154	amidase activity
Arad_8562	COG4608	Belongs to the ABC transporter superfamily
Arad_8565	COG0601	transmembrane transport
Arad_8567	COG1802	Transcriptional regulator
Arad_8570	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_8574	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_8579	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arad_8582	COG0745	RESPONSE REGULATOR receiver
Arad_8583	COG2205	protein histidine kinase activity
Arad_8585	COG4770	biotin carboxylase activity
Arad_8586	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_8587	COG4336	lyase activity
Arad_8588	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Arad_8589	COG1914	H( )-stimulated, divalent metal cation uptake system
Arad_8590	COG1802	Transcriptional regulator
Arad_8596	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Arad_8600	COG1129	ABC transporter
Arad_8601	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_8604	COG0667	Aldo Keto reductase
Arad_8605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Arad_8607	COG1070	Carbohydrate kinase
Arad_8611	COG1175	transmembrane transport
Arad_8613	COG0395	ABC-type sugar transport system, permease component
Arad_8614	COG3842	ATPase activity
Arad_8617	COG4948	Mandelate Racemase Muconate Lactonizing
Arad_8618	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8619	COG1063	alcohol dehydrogenase
Arad_8622	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arad_8624	COG1309	transcriptional regulator
Arad_8625	COG0673	inositol 2-dehydrogenase activity
Arad_8633	COG0625	glutathione transferase activity
Arad_8634	COG0583	DNA-binding transcription factor activity
Arad_8637	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_8642	COG1349	DNA-binding transcription factor activity
Arad_8644	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8644	COG3347	Dehydrogenase
Arad_8646	COG4952	isomerase
Arad_8652	COG1940	carbohydrate kinase activity
Arad_8655	COG4106	trans-aconitate 2-methyltransferase activity
Arad_8656	COG0386	Belongs to the glutathione peroxidase family
Arad_8660	COG0405	Gamma-glutamyltransferase
Arad_8665	COG2186	Transcriptional regulator
Arad_8668	COG1940	carbohydrate kinase activity
Arad_8674	COG2814	Major facilitator Superfamily
Arad_8675	COG2186	Transcriptional regulator
Arad_8676	COG0477	Major facilitator Superfamily
Arad_8677	COG1063	alcohol dehydrogenase
Arad_8679	COG4651	solute:proton antiporter activity
Arad_8679	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Arad_8684	COG1464	Belongs to the NlpA lipoprotein family
Arad_8686	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Arad_8688	COG2011	ABC-type metal ion transport system permease component
Arad_8693	COG4977	sequence-specific DNA binding
Arad_8696	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Arad_8702	COG0243	molybdopterin cofactor binding
Arad_8704	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Arad_8705	COG1116	anion transmembrane transporter activity
Arad_8706	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_8707	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_8708	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_8709	COG3707	response regulator
Arad_8714	COG1064	alcohol dehydrogenase
Arad_8716	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Arad_8717	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Arad_8718	COG0535	radical SAM domain protein
Arad_8719	COG0535	radical SAM domain protein
Arad_8721	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Arad_8727	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Arad_8730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Arad_8737	COG0583	DNA-binding transcription factor activity
Arad_8739	COG1301	dicarboxylic acid transport
Arad_8744	COG0459	protein refolding
Arad_8745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Arad_8754	COG2207	Transcriptional regulator
Arad_8765	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Arad_8766	COG4790	Type iii secretion
Arad_8768	COG1987	bacterial-type flagellum assembly
Arad_8772	COG4792	protein secretion
Arad_8774	COG4789	Type iii secretion
Arad_8781	COG2217	Heavy metal translocating P-type atpase
Arad_8783	COG0330	HflC and HflK could
Arad_8787	COG4608	Belongs to the ABC transporter superfamily
Arad_8788	COG0444	Belongs to the ABC transporter superfamily
Arad_8789	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_8790	COG0601	transmembrane transport
Arad_8791	COG0747	negative chemotaxis
Arad_8792	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_8794	COG1454	alcohol dehydrogenase
Arad_8795	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Arad_8796	COG0583	DNA-binding transcription factor activity
Arad_8797	COG5383	Protein conserved in bacteria
Arad_8801	COG0683	leucine binding
Arad_8803	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_8808	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Arad_8812	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arad_8813	COG1120	ATPase activity
Arad_8815	COG2226	methyltransferase
Arad_8820	COG0765	amino acid transport
Arad_8821	COG1126	abc transporter atp-binding protein
Arad_8823	COG1473	amidohydrolase
Arad_8824	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_8825	COG1802	Transcriptional regulator
Arad_8827	COG0318	PFAM AMP-dependent synthetase and ligase
Arad_8830	COG1522	sequence-specific DNA binding
Arad_8832	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Arad_8835	COG1802	Transcriptional regulator
Arad_8839	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_8840	COG4172	Belongs to the ABC transporter superfamily
Arad_8848	COG2186	Transcriptional regulator
Arad_8849	COG1027	Aspartate ammonia-lyase
Arad_8852	COG0252	asparaginase activity
Arad_8855	COG0668	transmembrane transport
Arad_8856	COG0850	regulation of cytokinetic process
Arad_8857	COG2894	cell division
Arad_8858	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Arad_8861	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
Arad_8862	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_8863	COG2273	Hydrolase Family 16
Arad_8863	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Arad_8870	COG0450	alkyl hydroperoxide reductase
Arad_8871	COG0583	DNA-binding transcription factor activity
Arad_8873	COG0667	Aldo Keto reductase
Arad_8874	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Arad_8880	COG1473	amidohydrolase
Arad_8882	COG0667	Aldo Keto reductase
Arad_8883	COG1802	Transcriptional regulator
Arad_8885	COG1312	Catalyzes the dehydration of D-mannonate
Arad_8887	COG0246	Mannitol dehydrogenase
Arad_8888	COG1063	alcohol dehydrogenase
Arad_8890	COG0765	amino acid transport
Arad_8892	COG0765	amino acid transport
Arad_8893	COG1126	abc transporter atp-binding protein
Arad_8894	COG1802	Transcriptional regulator
Arad_8896	COG2137	regulation of response to DNA damage stimulus
Arad_8900	COG1609	Transcriptional regulator
Arad_8904	COG4172	Belongs to the ABC transporter superfamily
Arad_8907	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_8908	COG0584	glycerophosphoryl diester phosphodiesterase
Arad_8910	COG0601	transmembrane transport
Arad_8911	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_8912	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8916	COG4608	Belongs to the ABC transporter superfamily
Arad_8917	COG0747	negative chemotaxis
Arad_8918	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Arad_8920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_8921	COG1116	anion transmembrane transporter activity
Arad_8928	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Arad_8930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Arad_8932	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_8933	COG1737	Transcriptional regulator
Arad_8934	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Arad_8935	COG2971	BadF BadG BcrA BcrD
Arad_8937	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Arad_8938	COG0747	negative chemotaxis
Arad_8939	COG0601	transmembrane transport
Arad_8942	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Arad_8943	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Arad_8947	COG0243	molybdopterin cofactor binding
Arad_8960	COG0625	glutathione transferase activity
Arad_8961	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
Arad_8966	COG1175	transmembrane transport
Arad_8968	COG1609	Transcriptional regulator
Arad_8972	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Arad_8974	COG4191	Histidine kinase
Arad_8975	COG2204	response regulator
Arad_8977	COG0395	ABC-type sugar transport system, permease component
Arad_8978	COG1175	transmembrane transport
Arad_8982	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_8983	COG1830	Aldolase
Arad_8985	COG1349	DNA-binding transcription factor activity
Arad_8995	COG5342	invasion associated locus B
Arad_8996	COG1278	Cold shock
Arad_8997	COG0517	IMP dehydrogenase activity
Arad_8997	COG4175	Glycine betaine
Arad_8998	COG4176	ABC-type proline glycine betaine transport system permease component
Arad_9000	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Arad_9002	COG0446	pyridine nucleotide-disulphide oxidoreductase
Arad_9002	COG1902	pentaerythritol trinitrate reductase activity
Arad_9006	COG0667	Aldo Keto reductase
Arad_9019	COG1902	pentaerythritol trinitrate reductase activity
Arad_9023	COG3344	reverse transcriptase
Arad_9032	COG0277	FAD linked oxidase domain protein
Arad_9047	COG0395	ABC-type sugar transport system, permease component
Arad_9050	COG1846	Transcriptional regulator
Arad_9050	COG1940	carbohydrate kinase activity
Arad_9054	COG4993	Dehydrogenase
Arad_9058	COG4213	ABC transporter substrate-binding protein
Arad_9059	COG1129	ABC transporter
Arad_9061	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9063	COG1215	transferase activity, transferring glycosyl groups
Arad_9064	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9068	COG1126	abc transporter atp-binding protein
Arad_9070	COG1473	amidohydrolase
Arad_9072	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9073	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9079	COG0395	ABC-type sugar transport system, permease component
Arad_9080	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_9083	COG3842	ATPase activity
Arad_9087	COG0657	acetylesterase activity
Arad_9087	COG2755	lipolytic protein G-D-S-L family
Arad_9091	COG2186	Transcriptional regulator
Arad_9096	COG0395	ABC-type sugar transport system, permease component
Arad_9098	COG3842	ATPase activity
Arad_9099	COG0006	proline dipeptidase activity
Arad_9101	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_9104	COG4585	Histidine kinase
Arad_9105	COG2197	response regulator
Arad_9111	COG1126	abc transporter atp-binding protein
Arad_9112	COG0765	amino acid transport
Arad_9114	COG0765	amino acid transport
Arad_9118	COG0583	DNA-binding transcription factor activity
Arad_9120	COG0436	Aminotransferase
Arad_9124	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_9126	COG1136	(ABC) transporter
Arad_9126	COG0577	efflux transmembrane transporter activity
Arad_9127	COG2205	protein histidine kinase activity
Arad_9128	COG0745	RESPONSE REGULATOR receiver
Arad_9131	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Arad_9134	COG2207	Transcriptional regulator
Arad_9154	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Arad_9160	COG1414	Transcriptional regulator
Arad_9163	COG0454	-acetyltransferase
Arad_9165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arad_9166	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Arad_9168	COG1012	belongs to the aldehyde dehydrogenase family
Arad_9172	COG0251	oxidation-reduction process
Arad_9174	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_9182	COG0601	transmembrane transport
Arad_9184	COG4172	Belongs to the ABC transporter superfamily
Arad_9185	COG1522	sequence-specific DNA binding
Arad_9188	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_9189	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arad_9190	COG1120	ATPase activity
Arad_9192	COG2819	hydrolase of the alpha beta superfamily
Arad_9194	COG4774	siderophore transport
Arad_9199	COG0747	negative chemotaxis
Arad_9202	COG1414	Transcriptional regulator
Arad_9203	COG2169	Transcriptional regulator
Arad_9205	COG1136	(ABC) transporter
Arad_9207	COG0577	efflux transmembrane transporter activity
Arad_9207	COG1136	(ABC) transporter
Arad_9208	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Arad_9210	COG1301	dicarboxylic acid transport
Arad_9211	COG4191	Histidine kinase
Arad_9212	COG2204	response regulator
Arad_9216	COG0625	glutathione transferase activity
Arad_9219	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
Arad_9220	COG0352	thiamine-phosphate diphosphorylase activity
Arad_9223	COG2824	Alkylphosphonate utilization operon protein PhnA
Arad_9224	COG1968	undecaprenyl-diphosphatase activity
Arad_9228	COG2186	Transcriptional regulator
Arad_9230	COG1850	ribulose-bisphosphate carboxylase activity
Arad_9232	COG0287	Prephenate dehydrogenase
Arad_9233	COG1879	ABC-type sugar transport system periplasmic component
Arad_9236	COG1129	ABC transporter
Arad_9237	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9238	COG0673	inositol 2-dehydrogenase activity
Arad_9240	COG2376	Dihydroxyacetone kinase
Arad_9241	COG1461	Dihydroxyacetone kinase
Arad_9246	COG0395	ABC-type sugar transport system, permease component
Arad_9248	COG3842	ATPase activity
Arad_9252	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_9253	COG1126	abc transporter atp-binding protein
Arad_9255	COG1609	Transcriptional regulator
Arad_9257	COG0583	DNA-binding transcription factor activity
Arad_9259	COG3246	L-lysine catabolic process to acetate
Arad_9260	COG1250	3-hydroxyacyl-CoA dehydrogenase
Arad_9260	COG0824	Thioesterase
Arad_9261	COG1960	acyl-CoA dehydrogenase activity
Arad_9265	COG0747	negative chemotaxis
Arad_9267	COG0601	transmembrane transport
Arad_9268	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9272	COG4166	transmembrane transport
Arad_9279	COG0583	DNA-binding transcription factor activity
Arad_9281	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Arad_9282	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Arad_9283	COG0745	RESPONSE REGULATOR receiver
Arad_9287	COG3300	MHYT domain
Arad_9287	COG5001	Diguanylate cyclase
Arad_9289	COG1120	ATPase activity
Arad_9290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arad_9291	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Arad_9297	COG0765	amino acid transport
Arad_9298	COG1126	abc transporter atp-binding protein
Arad_9299	COG2079	MmgE PrpD family protein
Arad_9304	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Arad_9304	COG2755	lipolytic protein G-D-S-L family
Arad_9305	COG1216	Glycosyl transferase, family 2
Arad_9306	COG0463	Glycosyl transferase, family 2
Arad_9308	COG1132	(ABC) transporter
Arad_9310	COG1733	regulation of RNA biosynthetic process
Arad_9313	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9315	COG0747	negative chemotaxis
Arad_9323	COG0697	spore germination
Arad_9324	COG1653	transport
Arad_9326	COG1175	transmembrane transport
Arad_9327	COG0395	ABC-type sugar transport system, permease component
Arad_9328	COG3842	ATPase activity
Arad_9331	COG1392	Phosphate transport regulator
Arad_9333	COG0306	phosphate transporter
Arad_9335	COG0747	negative chemotaxis
Arad_9337	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9339	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Arad_9343	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Arad_9344	COG1802	Transcriptional regulator
Arad_9346	COG0601	transmembrane transport
Arad_9349	COG1473	amidohydrolase
Arad_9351	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_9358	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_9360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9362	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_9363	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9364	COG0583	DNA-binding transcription factor activity
Arad_9370	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Arad_9380	COG1215	transferase activity, transferring glycosyl groups
Arad_9390	COG0438	transferase activity, transferring glycosyl groups
Arad_9391	COG1596	polysaccharide export
Arad_9396	COG1396	sequence-specific DNA binding
Arad_9398	COG2205	protein histidine kinase activity
Arad_9399	COG0745	RESPONSE REGULATOR receiver
Arad_9405	COG0659	secondary active sulfate transmembrane transporter activity
Arad_9408	COG1278	Cold shock
Arad_9421	COG1082	Xylose isomerase domain protein TIM barrel
Arad_9422	COG1609	Transcriptional regulator
Arad_9424	COG1129	ABC transporter
Arad_9425	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9428	COG0235	Class ii aldolase
Arad_9432	COG0251	oxidation-reduction process
Arad_9434	COG0765	amino acid transport
Arad_9435	COG0765	amino acid transport
Arad_9437	COG1609	Transcriptional regulator
Arad_9438	COG2271	Major facilitator Superfamily
Arad_9439	COG2084	Dehydrogenase
Arad_9440	COG3622	Belongs to the hyi family
Arad_9441	COG3395	kinase activity
Arad_9442	COG0235	Class ii aldolase
Arad_9445	COG0745	RESPONSE REGULATOR receiver
Arad_9445	COG3706	GGDEF domain
Arad_9447	COG2197	response regulator
Arad_9452	COG4608	Belongs to the ABC transporter superfamily
Arad_9453	COG0444	Belongs to the ABC transporter superfamily
Arad_9454	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9462	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Arad_9463	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Arad_9464	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Arad_9466	COG2205	protein histidine kinase activity
Arad_9468	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Arad_9469	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Arad_9472	COG4208	sulfate ABC transporter
Arad_9473	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Arad_9474	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Arad_9478	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Arad_9491	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Arad_9496	COG1414	Transcriptional regulator
Arad_9499	COG0583	DNA-binding transcription factor activity
Arad_9500	COG2267	carboxylic ester hydrolase activity
Arad_9502	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Arad_9503	COG3485	protocatechuate 3,4-dioxygenase
Arad_9504	COG3485	protocatechuate 3,4-dioxygenase
Arad_9506	COG0683	leucine binding
Arad_9508	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_9513	COG1234	tRNA 3'-trailer cleavage
Arad_9517	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Arad_9525	COG0747	negative chemotaxis
Arad_9527	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9531	COG1132	(ABC) transporter
Arad_9532	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Arad_9532	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Arad_9538	COG1486	melibiose metabolic process
Arad_9539	COG4172	Belongs to the ABC transporter superfamily
Arad_9540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9543	COG0601	transmembrane transport
Arad_9544	COG0747	negative chemotaxis
Arad_9545	COG1486	melibiose metabolic process
Arad_9546	COG2207	Transcriptional regulator
Arad_9551	COG2721	sulfolactate sulfo-lyase activity
Arad_9556	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9559	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Arad_9561	COG3307	-O-antigen
Arad_9562	COG1596	polysaccharide export
Arad_9565	COG1215	transferase activity, transferring glycosyl groups
Arad_9566	COG2327	Polysaccharide pyruvyl transferase
Arad_9567	COG0463	Glycosyl transferase, family 2
Arad_9569	COG2244	polysaccharide biosynthetic process
Arad_9570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Arad_9571	COG2273	Hydrolase Family 16
Arad_9573	COG0438	transferase activity, transferring glycosyl groups
Arad_9574	COG1215	transferase activity, transferring glycosyl groups
Arad_9575	COG1215	transferase activity, transferring glycosyl groups
Arad_9576	COG1215	transferase activity, transferring glycosyl groups
Arad_9577	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Arad_9578	COG0489	protein tyrosine kinase activity
Arad_9578	COG3206	protein involved in exopolysaccharide biosynthesis
Arad_9579	COG0697	spore germination
Arad_9585	COG1609	Transcriptional regulator
Arad_9587	COG0864	Transcriptional regulator
Arad_9601	COG1522	sequence-specific DNA binding
Arad_9606	COG1126	abc transporter atp-binding protein
Arad_9608	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_9618	COG1879	ABC-type sugar transport system periplasmic component
Arad_9619	COG1940	carbohydrate kinase activity
Arad_9622	COG2390	Transcriptional regulator
Arad_9623	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Arad_9624	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
Arad_9625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_9628	COG0673	inositol 2-dehydrogenase activity
Arad_9631	COG0395	ABC-type sugar transport system, permease component
Arad_9637	COG1940	carbohydrate kinase activity
Arad_9638	COG3842	ATPase activity
Arad_9639	COG4172	Belongs to the ABC transporter superfamily
Arad_9644	COG0601	transmembrane transport
Arad_9645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9647	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Arad_9648	COG1070	Carbohydrate kinase
Arad_9651	COG4214	carbohydrate transport
Arad_9656	COG0840	transmembrane signaling receptor activity
Arad_9660	COG1129	ABC transporter
Arad_9661	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9666	COG1609	Transcriptional regulator
Arad_9669	COG2084	Dehydrogenase
Arad_9671	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_9672	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Arad_9673	COG1063	alcohol dehydrogenase
Arad_9676	COG3386	PFAM SMP-30 Gluconolaconase
Arad_9679	COG4172	Belongs to the ABC transporter superfamily
Arad_9680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9683	COG0747	negative chemotaxis
Arad_9685	COG1473	amidohydrolase
Arad_9688	COG4774	siderophore transport
Arad_9693	COG2205	protein histidine kinase activity
Arad_9694	COG0745	RESPONSE REGULATOR receiver
Arad_9697	COG4172	Belongs to the ABC transporter superfamily
Arad_9699	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9700	COG0601	transmembrane transport
Arad_9702	COG2186	Transcriptional regulator
Arad_9703	COG1312	Catalyzes the dehydration of D-mannonate
Arad_9704	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_9705	COG2706	6-phosphogluconolactonase activity
Arad_9707	COG0410	ABC transporter
Arad_9709	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9710	COG0559	Belongs to the binding-protein-dependent transport system permease family
Arad_9713	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9717	COG3842	ATPase activity
Arad_9718	COG1177	transmembrane transport
Arad_9719	COG1176	ABC-type spermidine putrescine transport system, permease component I
Arad_9724	COG1012	belongs to the aldehyde dehydrogenase family
Arad_9725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Arad_9727	COG2267	carboxylic ester hydrolase activity
Arad_9732	COG0602	queuosine metabolic process
Arad_9733	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Arad_9736	COG2197	response regulator
Arad_9738	COG1280	lysine exporter protein (LysE YggA)
Arad_9740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Arad_9746	COG2211	Major facilitator Superfamily
Arad_9752	COG2272	Belongs to the type-B carboxylesterase lipase family
Arad_9765	COG2186	Transcriptional regulator
Arad_9766	COG0747	negative chemotaxis
Arad_9769	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_9770	COG0444	Belongs to the ABC transporter superfamily
Arad_9778	COG1595	DNA-templated transcription, initiation
Arad_9781	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Arad_9784	COG1175	transmembrane transport
Arad_9786	COG3842	ATPase activity
Arad_9787	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_9790	COG0159	tryptophan synthase activity
Arad_9791	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Arad_9795	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9812	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Arad_9814	COG4608	Belongs to the ABC transporter superfamily
Arad_9817	COG0601	transmembrane transport
Arad_9821	COG2801	Transposase and inactivated derivatives
Arad_9824	COG1653	transport
Arad_9826	COG0395	ABC-type sugar transport system, permease component
Arad_9834	COG2072	flavoprotein involved in K transport
Arad_9836	COG3547	Transposase (IS116 IS110 IS902 family)
Arad_9838	COG2814	Major facilitator Superfamily
Arad_9841	COG2207	Transcriptional regulator
Arad_9845	COG1228	amidohydrolase
Arad_9850	COG1741	Belongs to the pirin family
Arad_9851	COG0583	DNA-binding transcription factor activity
Arad_9854	COG1335	isochorismatase
Arad_9857	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_9857	COG3321	synthase
Arad_9857	COG0604	alcohol dehydrogenase
Arad_9859	COG1028	Short-chain dehydrogenase reductase Sdr
Arad_9865	COG1733	regulation of RNA biosynthetic process
Arad_9870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Arad_9872	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Arad_9879	COG1070	Carbohydrate kinase
Arad_9880	COG0434	BtpA family
Arad_9883	COG1335	isochorismatase
Arad_9888	COG2072	flavoprotein involved in K transport
Arad_9892	COG1349	DNA-binding transcription factor activity
Arad_9897	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Arad_9899	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Arad_9900	COG0587	DNA-directed DNA polymerase activity
Arad_9902	COG1309	transcriptional regulator
Arad_9903	COG4221	oxidoreductase activity
Arad_9910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Arad_9912	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Arad_9913	COG1845	cytochrome c oxidase, subunit III
Arad_9914	COG1845	cytochrome c oxidase, subunit III
Arad_9916	COG2072	flavoprotein involved in K transport
Arad_9917	COG1254	Belongs to the acylphosphatase family
Arad_9934	COG1937	Protein conserved in bacteria
Arad_9940	COG0601	transmembrane transport
Arad_9942	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Arad_9943	COG2186	Transcriptional regulator
Arad_9944	COG0444	Belongs to the ABC transporter superfamily
Arad_9954	COG2801	Transposase and inactivated derivatives
Arad_9956	COG3344	reverse transcriptase
Arad_9959	COG1902	pentaerythritol trinitrate reductase activity
Arad_9962	COG1609	Transcriptional regulator
Arad_9963	COG1840	ABC-type Fe3 transport system, periplasmic component
Arad_9965	COG3842	ATPase activity
Arad_9974	COG1215	transferase activity, transferring glycosyl groups
Arad_9976	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Arad_9978	COG4251	negative regulation of phosphorylation
Arad_9978	COG5001	Diguanylate cyclase
Arad_9978	COG2203	Gaf domain
Arad_9978	COG3706	GGDEF domain
Arad_9979	COG1609	Transcriptional regulator
Arad_9980	COG1609	Transcriptional regulator
Arad_9982	COG1129	ABC transporter
Arad_9983	COG1172	Belongs to the binding-protein-dependent transport system permease family
Arad_9998	COG1459	type II secretion system
Arad_9999	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB