locus-tag	class	description
EML492_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EML492_00020	COG0697	spore germination
EML492_00025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EML492_00030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EML492_00040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EML492_00045	COG1420	regulation of RNA biosynthetic process
EML492_00055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EML492_00060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML492_00065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EML492_00075	COG1137	ATPase activity
EML492_00080	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EML492_00090	COG0616	signal peptide processing
EML492_00095	COG0776	regulation of translation
EML492_00120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EML492_00125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EML492_00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EML492_00150	COG0280	phosphate acetyltransferase
EML492_00150	COG0281	malic enzyme
EML492_00155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EML492_00185	COG0180	Tryptophanyl-tRNA synthetase
EML492_00195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EML492_00220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EML492_00225	COG1702	phosphate starvation-inducible protein PhoH
EML492_00230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EML492_00240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EML492_00245	COG1396	sequence-specific DNA binding
EML492_00250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EML492_00255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EML492_00275	COG0840	transmembrane signaling receptor activity
EML492_00280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_00290	COG0242	peptide deformylase activity
EML492_00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EML492_00310	COG0101	tRNA pseudouridine synthase activity
EML492_00315	COG0579	oxidoreductase
EML492_00325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_00330	COG2171	N-acyltransferase activity
EML492_00340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EML492_00360	COG0300	oxidoreductase activity
EML492_00365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EML492_00380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EML492_00385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EML492_00390	COG2207	Transcriptional regulator
EML492_00390	COG3708	Transcriptional regulator
EML492_00400	COG0706	membrane insertase activity
EML492_00405	COG0594	ribonuclease P activity
EML492_00410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EML492_00415	COG2972	Histidine kinase
EML492_00415	COG0840	transmembrane signaling receptor activity
EML492_00440	COG1733	regulation of RNA biosynthetic process
EML492_00460	COG0477	Major facilitator Superfamily
EML492_00480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EML492_00490	COG0583	DNA-binding transcription factor activity
EML492_00495	COG0300	oxidoreductase activity
EML492_00500	COG0667	Aldo Keto reductase
EML492_00510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_00515	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_00520	COG3938	Belongs to the proline racemase family
EML492_00550	COG1072	(Pantothenic acid kinase))
EML492_00555	COG0418	dihydroorotase activity
EML492_00565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EML492_00575	COG0166	Belongs to the GPI family
EML492_00580	COG0318	PFAM AMP-dependent synthetase and ligase
EML492_00590	COG0346	lactoylglutathione lyase activity
EML492_00595	COG3795	YCII-related domain
EML492_00600	COG1174	glycine betaine transport
EML492_00605	COG1125	glycine betaine transport
EML492_00610	COG1174	glycine betaine transport
EML492_00615	COG1732	Glycine betaine
EML492_00620	COG0583	DNA-binding transcription factor activity
EML492_00655	COG2326	polyphosphate kinase activity
EML492_00660	COG5002	protein histidine kinase activity
EML492_00670	COG0573	inorganic phosphate transmembrane transporter activity
EML492_00675	COG0581	inorganic phosphate transmembrane transporter activity
EML492_00680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EML492_00685	COG0704	Plays a role in the regulation of phosphate uptake
EML492_00690	COG0745	RESPONSE REGULATOR receiver
EML492_00700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EML492_00705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EML492_00710	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EML492_00715	COG2967	ApaG domain
EML492_00725	COG0717	Belongs to the dCTP deaminase family
EML492_00735	COG0110	maltose O-acetyltransferase activity
EML492_00770	COG0167	dihydroorotate dehydrogenase activity
EML492_00775	COG0534	Mate efflux family protein
EML492_00795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EML492_00805	COG0174	glutamine synthetase
EML492_00810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EML492_00815	COG1959	2 iron, 2 sulfur cluster binding
EML492_00820	COG1201	RNA secondary structure unwinding
EML492_00845	COG0730	response to heat
EML492_00860	COG1960	acyl-CoA dehydrogenase activity
EML492_00865	COG0183	Belongs to the thiolase family
EML492_00870	COG1250	3-hydroxyacyl-CoA dehydrogenase
EML492_00870	COG1024	Enoyl-CoA hydratase
EML492_00885	COG1970	mechanosensitive ion channel activity
EML492_00890	COG0436	Aminotransferase
EML492_00925	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_00935	COG1024	Enoyl-CoA hydratase
EML492_00965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EML492_00965	COG4651	solute:proton antiporter activity
EML492_00975	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EML492_00980	COG0840	transmembrane signaling receptor activity
EML492_00990	COG0745	RESPONSE REGULATOR receiver
EML492_00995	COG2198	Histidine kinase
EML492_00995	COG0643	Histidine kinase
EML492_01000	COG0835	chemotaxis
EML492_01005	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EML492_01010	COG2201	protein-glutamate methylesterase activity
EML492_01015	COG0745	RESPONSE REGULATOR receiver
EML492_01020	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EML492_01030	COG1766	The M ring may be actively involved in energy transduction
EML492_01035	COG2771	luxR family
EML492_01050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EML492_01055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML492_01060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML492_01065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML492_01070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EML492_01075	COG4786	Flagellar basal body rod
EML492_01080	COG1157	protein secretion by the type III secretion system
EML492_01090	COG1815	bacterial-type flagellum-dependent cell motility
EML492_01095	COG1558	bacterial-type flagellum-dependent cell motility
EML492_01100	COG1677	Flagellar hook-basal body complex protein FliE
EML492_01105	COG4786	Flagellar basal body rod
EML492_01110	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EML492_01115	COG1706	bacterial-type flagellum-dependent cell motility
EML492_01125	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EML492_01135	COG1338	Plays a role in the flagellum-specific transport system
EML492_01155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EML492_01165	COG0076	glutamate decarboxylase activity
EML492_01175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EML492_01210	COG1749	Flagellar hook protein flgE
EML492_01230	COG5443	negative regulation of bacterial-type flagellum assembly
EML492_01240	COG4794	Type iii secretion
EML492_01245	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EML492_01250	COG1684	flagellar biosynthetic protein fliR
EML492_01285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EML492_01290	COG1609	Transcriptional regulator
EML492_01295	COG1653	transport
EML492_01300	COG1175	transmembrane transport
EML492_01305	COG0395	ABC-type sugar transport system, permease component
EML492_01310	COG0366	Alpha amylase catalytic
EML492_01315	COG3842	ATPase activity
EML492_01335	COG0129	dihydroxy-acid dehydratase activity
EML492_01340	COG0363	glucosamine-6-phosphate deaminase activity
EML492_01345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EML492_01350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_01360	COG2081	HI0933 family
EML492_01375	COG2972	Histidine kinase
EML492_01375	COG0840	transmembrane signaling receptor activity
EML492_01385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EML492_01390	COG3842	ATPase activity
EML492_01395	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_01400	COG1177	transmembrane transport
EML492_01410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML492_01415	COG0513	Belongs to the DEAD box helicase family
EML492_01425	COG2205	protein histidine kinase activity
EML492_01465	COG4269	membrane
EML492_01475	COG1959	2 iron, 2 sulfur cluster binding
EML492_01480	COG0747	negative chemotaxis
EML492_01485	COG0601	transmembrane transport
EML492_01490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_01495	COG0444	Belongs to the ABC transporter superfamily
EML492_01500	COG4608	Belongs to the ABC transporter superfamily
EML492_01505	COG3265	gluconokinase activity
EML492_01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_01515	COG1755	Isoprenylcysteine carboxyl methyltransferase
EML492_01530	COG1595	DNA-templated transcription, initiation
EML492_01545	COG0583	DNA-binding transcription factor activity
EML492_01555	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EML492_01565	COG0477	Major facilitator Superfamily
EML492_01595	COG0583	DNA-binding transcription factor activity
EML492_01605	COG0488	(ABC) transporter
EML492_01635	COG0306	phosphate transporter
EML492_01650	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EML492_01655	COG0583	DNA-binding transcription factor activity
EML492_01660	COG0277	FAD linked oxidase domain protein
EML492_01665	COG0277	FAD linked oxidase domain protein
EML492_01670	COG0247	lactate metabolic process
EML492_01685	COG1376	ErfK ybiS ycfS ynhG family protein
EML492_01690	COG1376	ErfK ybiS ycfS ynhG family protein
EML492_01695	COG2818	Glycosylase
EML492_01710	COG0667	Aldo Keto reductase
EML492_01715	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_01715	COG0604	alcohol dehydrogenase
EML492_01715	COG3321	synthase
EML492_01720	COG0583	DNA-binding transcription factor activity
EML492_01745	COG0124	histidyl-tRNA synthetase
EML492_01750	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EML492_01755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EML492_01770	COG2259	Doxx family
EML492_01775	COG0625	glutathione transferase activity
EML492_01790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EML492_01805	COG0196	riboflavin kinase activity
EML492_01840	COG0590	tRNA wobble adenosine to inosine editing
EML492_01845	COG1187	pseudouridine synthase activity
EML492_01850	COG0742	ribosomal rna small subunit methyltransferase
EML492_01860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EML492_01860	COG0475	glutathione-regulated potassium exporter activity
EML492_01865	COG0312	modulator of DNA gyrase
EML492_01870	COG0483	inositol monophosphate 1-phosphatase activity
EML492_01880	COG1519	Transferase
EML492_01890	COG1663	tetraacyldisaccharide 4'-kinase activity
EML492_01900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EML492_01905	COG0745	RESPONSE REGULATOR receiver
EML492_01910	COG3300	MHYT domain
EML492_01910	COG5001	Diguanylate cyclase
EML492_01920	COG0137	argininosuccinate synthase activity
EML492_01930	COG3386	PFAM SMP-30 Gluconolaconase
EML492_01935	COG0800	Aldolase
EML492_01940	COG3734	2-keto-3-deoxy-galactonokinase
EML492_01945	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_01950	COG1414	Transcriptional regulator
EML492_01955	COG2197	response regulator
EML492_01960	COG0489	protein tyrosine kinase activity
EML492_01965	COG0598	Magnesium transport protein CorA
EML492_01970	COG3158	transport of potassium into the cell
EML492_01985	COG0356	it plays a direct role in the translocation of protons across the membrane
EML492_01990	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EML492_01995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EML492_02000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EML492_02010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EML492_02030	COG0521	Mo-molybdopterin cofactor biosynthetic process
EML492_02035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EML492_02045	COG0142	geranyltranstransferase activity
EML492_02065	COG1396	sequence-specific DNA binding
EML492_02100	COG0752	glycyl-tRNA synthetase alpha subunit
EML492_02105	COG1704	LemA family
EML492_02110	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EML492_02125	COG0751	glycine-tRNA ligase activity
EML492_02130	COG1683	Conserved Protein
EML492_02135	COG0840	transmembrane signaling receptor activity
EML492_02145	COG0151	Belongs to the GarS family
EML492_02150	COG2183	response to ionizing radiation
EML492_02155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EML492_02175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EML492_02200	COG0277	FAD linked oxidase domain protein
EML492_02205	COG0009	L-threonylcarbamoyladenylate synthase
EML492_02220	COG4638	Rieske (2fe-2S)
EML492_02245	COG1960	acyl-CoA dehydrogenase activity
EML492_02255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EML492_02265	COG0840	transmembrane signaling receptor activity
EML492_02275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EML492_02280	COG1741	Belongs to the pirin family
EML492_02285	COG1722	exodeoxyribonuclease VII activity
EML492_02290	COG0123	including yeast histone deacetylase and acetoin utilization protein
EML492_02305	COG1268	BioY protein
EML492_02310	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EML492_02315	COG1122	ATPase activity
EML492_02320	COG3214	Protein conserved in bacteria
EML492_02325	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EML492_02325	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EML492_02330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EML492_02340	COG0406	alpha-ribazole phosphatase activity
EML492_02345	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EML492_02350	COG0484	heat shock protein binding
EML492_02360	COG0259	pyridoxamine-phosphate oxidase activity
EML492_02370	COG1686	Belongs to the peptidase S11 family
EML492_02380	COG0312	modulator of DNA gyrase
EML492_02390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EML492_02395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EML492_02400	COG0109	protoheme IX farnesyltransferase activity
EML492_02410	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EML492_02420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML492_02425	COG0640	Transcriptional regulator
EML492_02450	COG3346	SURF1 family
EML492_02455	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EML492_02460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EML492_02465	COG0328	RNA-DNA hybrid ribonuclease activity
EML492_02480	COG0803	Belongs to the bacterial solute-binding protein 9 family
EML492_02490	COG1121	(ABC) transporter
EML492_02495	COG0678	peroxiredoxin activity
EML492_02495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EML492_02505	COG1678	Uncharacterized ACR, COG1678
EML492_02525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EML492_02530	COG0612	Peptidase, M16
EML492_02545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML492_02555	COG1268	BioY protein
EML492_02565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EML492_02585	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EML492_02600	COG1194	a g-specific adenine glycosylase
EML492_02610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EML492_02615	COG1196	nuclear chromosome segregation
EML492_02620	COG1253	flavin adenine dinucleotide binding
EML492_02625	COG3093	addiction module antidote protein HigA
EML492_02635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EML492_02635	COG0574	Belongs to the PEP-utilizing enzyme family
EML492_02690	COG1956	GAF domain-containing protein
EML492_02700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EML492_02720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EML492_02735	COG0477	Major facilitator Superfamily
EML492_02745	COG2895	sulfate adenylyltransferase (ATP) activity
EML492_02750	COG0175	sulfate reduction
EML492_02755	COG0175	sulfate reduction
EML492_02760	COG1959	2 iron, 2 sulfur cluster binding
EML492_02780	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EML492_02785	COG1012	belongs to the aldehyde dehydrogenase family
EML492_02790	COG0625	glutathione transferase activity
EML492_02795	COG1309	transcriptional regulator
EML492_02810	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EML492_02835	COG1349	DNA-binding transcription factor activity
EML492_02845	COG0625	glutathione transferase activity
EML492_02875	COG1960	acyl-CoA dehydrogenase activity
EML492_02880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EML492_02920	COG1793	dna ligase
EML492_02945	COG1376	ErfK ybiS ycfS ynhG family protein
EML492_02950	COG1376	ErfK ybiS ycfS ynhG family protein
EML492_02955	COG1846	Transcriptional regulator
EML492_02960	COG1764	response to oxidative stress
EML492_02975	COG1846	Transcriptional regulator
EML492_02990	COG0433	COG0433 Predicted ATPase
EML492_03010	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EML492_03015	COG4106	trans-aconitate 2-methyltransferase activity
EML492_03025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EML492_03030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EML492_03040	COG2814	Major facilitator Superfamily
EML492_03075	COG1278	Cold shock
EML492_03080	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EML492_03090	COG2207	Transcriptional regulator
EML492_03095	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_03115	COG2010	Cytochrome c
EML492_03120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML492_03150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EML492_03185	COG0484	heat shock protein binding
EML492_03200	COG2514	catechol 2,3-dioxygenase activity
EML492_03205	COG1272	protein, Hemolysin III
EML492_03215	COG1247	-acetyltransferase
EML492_03220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EML492_03220	COG2111	Na H antiporter
EML492_03225	COG2111	Na H antiporter
EML492_03230	COG1006	Multisubunit Na H antiporter MnhC subunit
EML492_03235	COG0651	ATP synthesis coupled electron transport
EML492_03240	COG1863	multisubunit Na H antiporter MnhE subunit
EML492_03245	COG2212	antiporter activity
EML492_03250	COG1320	monovalent cation:proton antiporter activity
EML492_03255	COG4957	zinc ion binding
EML492_03260	COG2166	iron-sulfur cluster assembly
EML492_03270	COG2205	protein histidine kinase activity
EML492_03310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EML492_03315	COG2983	Belongs to the UPF0260 family
EML492_03345	COG4235	cytochrome complex assembly
EML492_03350	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EML492_03355	COG1138	Cytochrome C-type biogenesis protein
EML492_03360	COG3088	subunit of a heme lyase
EML492_03365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EML492_03370	COG0745	RESPONSE REGULATOR receiver
EML492_03375	COG2205	protein histidine kinase activity
EML492_03380	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EML492_03385	COG2205	protein histidine kinase activity
EML492_03385	COG2202	Pas domain
EML492_03390	COG0308	aminopeptidase N
EML492_03395	COG3290	protein histidine kinase activity
EML492_03395	COG0840	transmembrane signaling receptor activity
EML492_03415	COG1573	uracil-dna glycosylase
EML492_03420	COG0443	Heat shock 70 kDa protein
EML492_03430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_03435	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_03460	COG2239	Acts as a magnesium transporter
EML492_03470	COG1733	regulation of RNA biosynthetic process
EML492_03475	COG2814	Major facilitator Superfamily
EML492_03485	COG0174	glutamine synthetase
EML492_03500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EML492_03505	COG0463	Glycosyl transferase, family 2
EML492_03515	COG4941	Belongs to the sigma-70 factor family
EML492_03525	COG3795	YCII-related domain
EML492_03540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EML492_03565	COG0705	Rhomboid family
EML492_03565	COG0457	Tetratricopeptide repeat
EML492_03570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EML492_03595	COG3718	enzyme involved in inositol metabolism
EML492_03600	COG1082	Xylose isomerase domain protein TIM barrel
EML492_03605	COG3962	Belongs to the TPP enzyme family
EML492_03610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_03665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EML492_03750	COG1061	Type III restriction enzyme res subunit
EML492_03855	COG4695	Portal protein
EML492_04040	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EML492_04045	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EML492_04085	COG0798	PFAM Bile acid sodium symporter
EML492_04095	COG0640	Transcriptional regulator
EML492_04115	COG0596	Alpha beta hydrolase
EML492_04115	COG2945	thiolester hydrolase activity
EML492_04120	COG0741	lytic transglycosylase activity
EML492_04125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_04130	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EML492_04140	COG1758	RNA polymerase activity
EML492_04160	COG0736	holo-[acyl-carrier-protein] synthase activity
EML492_04165	COG0681	Belongs to the peptidase S26 family
EML492_04170	COG0571	ribonuclease III activity
EML492_04175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EML492_04185	COG1381	Involved in DNA repair and RecF pathway recombination
EML492_04195	COG1418	mRNA catabolic process
EML492_04210	COG2032	superoxide dismutase activity
EML492_04225	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EML492_04230	COG0354	folic acid binding
EML492_04255	COG1742	UPF0060 membrane protein
EML492_04270	COG1183	phosphatidylcholine synthase activity
EML492_04275	COG0688	phosphatidylethanolamine metabolic process
EML492_04280	COG0671	phosphoesterase, PA-phosphatase related
EML492_04285	COG5265	(ABC) transporter
EML492_04305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EML492_04330	COG0215	cysteine-tRNA ligase activity
EML492_04335	COG4221	oxidoreductase activity
EML492_04340	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EML492_04345	COG1286	toxin biosynthetic process
EML492_04355	COG1280	lysine exporter protein (LysE YggA)
EML492_04360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EML492_04365	COG0305	Participates in initiation and elongation during chromosome replication
EML492_04385	COG0359	binds to the 23S rRNA
EML492_04395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EML492_04400	COG0360	Binds together with S18 to 16S ribosomal RNA
EML492_04420	COG0667	Aldo Keto reductase
EML492_04425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EML492_04435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML492_04440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EML492_04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EML492_04450	COG1561	YicC-like family, N-terminal region
EML492_04455	COG0194	GDP metabolic process
EML492_04460	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EML492_04465	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EML492_04475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EML492_04490	COG0671	phosphoesterase, PA-phosphatase related
EML492_04495	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EML492_04505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EML492_04520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EML492_04520	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML492_04525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EML492_04530	COG1505	serine-type exopeptidase activity
EML492_04540	COG0488	(ABC) transporter
EML492_04555	COG0105	UTP biosynthetic process
EML492_04575	COG0314	molybdopterin synthase activity
EML492_04585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EML492_04590	COG0322	excinuclease ABC activity
EML492_04595	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_04605	COG0625	glutathione transferase activity
EML492_04610	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EML492_04615	COG0243	molybdopterin cofactor binding
EML492_04625	COG3454	Phosphonate metabolism
EML492_04630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EML492_04635	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EML492_04640	COG0628	permease
EML492_04650	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EML492_04655	COG0248	Ppx GppA phosphatase
EML492_04665	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EML492_04670	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EML492_04675	COG2132	Multicopper oxidase
EML492_04685	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EML492_04705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EML492_04710	COG3654	unkown
EML492_04725	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EML492_04735	COG0113	porphobilinogen synthase activity
EML492_04755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EML492_04760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EML492_04765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EML492_04765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EML492_04775	COG0454	-acetyltransferase
EML492_04790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EML492_04795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EML492_04800	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EML492_04820	COG0416	fatty acid biosynthetic process
EML492_04825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EML492_04830	COG0776	regulation of translation
EML492_04885	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
EML492_04890	COG4423	Transcription factor
EML492_04900	COG0438	transferase activity, transferring glycosyl groups
EML492_04940	COG1612	heme a metabolic process
EML492_04950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EML492_04955	COG0010	Belongs to the arginase family
EML492_04970	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EML492_04975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EML492_04990	COG1832	CoA-binding protein
EML492_05000	COG1181	Belongs to the D-alanine--D-alanine ligase family
EML492_05010	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EML492_05015	COG0573	inorganic phosphate transmembrane transporter activity
EML492_05025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EML492_05030	COG2124	cytochrome p450
EML492_05035	COG3706	GGDEF domain
EML492_05040	COG0740	serine-type endopeptidase activity
EML492_05045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EML492_05050	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EML492_05055	COG0776	regulation of translation
EML492_05060	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_05065	COG0667	Aldo Keto reductase
EML492_05070	COG0420	3'-5' exonuclease activity
EML492_05075	COG4717	serine-type aminopeptidase activity
EML492_05085	COG0438	transferase activity, transferring glycosyl groups
EML492_05085	COG1216	Glycosyl transferase, family 2
EML492_05090	COG0604	alcohol dehydrogenase
EML492_05090	COG3321	synthase
EML492_05110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML492_05115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML492_05120	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML492_05125	COG0649	NAD binding
EML492_05135	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EML492_05140	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EML492_05145	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EML492_05145	COG3743	rRNA binding
EML492_05155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EML492_05160	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EML492_05170	COG0713	ATP synthesis coupled electron transport
EML492_05185	COG1007	ATP synthesis coupled electron transport
EML492_05200	COG0346	lactoylglutathione lyase activity
EML492_05215	COG0442	prolyl-tRNA aminoacylation
EML492_05225	COG1136	(ABC) transporter
EML492_05255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EML492_05275	COG0784	Response regulator, receiver
EML492_05285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EML492_05290	COG2814	Major facilitator Superfamily
EML492_05305	COG0557	exoribonuclease II activity
EML492_05310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EML492_05315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EML492_05315	COG0758	DNA mediated transformation
EML492_05320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EML492_05330	COG0540	Belongs to the ATCase OTCase family
EML492_05335	COG1960	acyl-CoA dehydrogenase activity
EML492_05340	COG3609	addiction module antidote protein, CC2985 family
EML492_05350	COG0456	acetyltransferase
EML492_05355	COG1309	transcriptional regulator
EML492_05370	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EML492_05375	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EML492_05380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EML492_05385	COG0154	amidase activity
EML492_05400	COG3811	Belongs to the UPF0386 family
EML492_05410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EML492_05430	COG4765	Protein conserved in bacteria
EML492_05445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EML492_05460	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EML492_05470	COG0436	Aminotransferase
EML492_05475	COG1530	ribonuclease E activity
EML492_05480	COG0860	N-Acetylmuramoyl-L-alanine amidase
EML492_05485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EML492_05495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EML492_05685	COG4197	protein conserved in bacteria, prophage-related
EML492_05750	COG0305	Participates in initiation and elongation during chromosome replication
EML492_05840	COG5410	chromosome segregation
EML492_06085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EML492_06110	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EML492_06115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EML492_06140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EML492_06150	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EML492_06155	COG0081	regulation of translation
EML492_06160	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EML492_06165	COG0222	ribosome binding
EML492_06170	COG0085	RNA polymerase activity
EML492_06175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EML492_06185	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EML492_06190	COG0049	tRNA binding
EML492_06195	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EML492_06200	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EML492_06205	COG0051	transcription antitermination factor activity, RNA binding
EML492_06210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EML492_06215	COG0088	Forms part of the polypeptide exit tunnel
EML492_06220	COG0089	rRNA binding
EML492_06225	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EML492_06230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EML492_06235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EML492_06240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EML492_06245	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EML492_06250	COG0255	Belongs to the universal ribosomal protein uL29 family
EML492_06255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EML492_06260	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EML492_06265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EML492_06270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EML492_06275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EML492_06280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EML492_06285	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EML492_06290	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EML492_06295	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EML492_06300	COG1841	ribosomal large subunit assembly
EML492_06305	COG0200	Binds to the 23S rRNA
EML492_06310	COG0201	protein transport
EML492_06315	COG0563	adenylate kinase activity
EML492_06320	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EML492_06325	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EML492_06330	COG0202	RNA polymerase activity
EML492_06335	COG0203	ribosomal protein L17
EML492_06340	COG3739	integral membrane protein
EML492_06355	COG1289	transmembrane transporter activity
EML492_06365	COG1566	PFAM secretion protein HlyD family protein
EML492_06370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EML492_06375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EML492_06380	COG0129	dihydroxy-acid dehydratase activity
EML492_06395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EML492_06415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_06435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EML492_06460	COG0488	(ABC) transporter
EML492_06465	COG1253	flavin adenine dinucleotide binding
EML492_06490	COG0789	Transcriptional regulator
EML492_06505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML492_06515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EML492_06520	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EML492_06530	COG1058	Belongs to the CinA family
EML492_06530	COG1546	Belongs to the CinA family
EML492_06535	COG0655	NAD(P)H dehydrogenase (quinone) activity
EML492_06545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EML492_06560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EML492_06575	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_06585	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EML492_06590	COG0583	DNA-binding transcription factor activity
EML492_06595	COG0737	Belongs to the 5'-nucleotidase family
EML492_06610	COG1522	sequence-specific DNA binding
EML492_06615	COG0686	Belongs to the AlaDH PNT family
EML492_06630	COG2897	thiosulfate sulfurtransferase activity
EML492_06635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EML492_06640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EML492_06645	COG0300	oxidoreductase activity
EML492_06650	COG3842	ATPase activity
EML492_06655	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EML492_06660	COG0395	ABC-type sugar transport system, permease component
EML492_06665	COG1175	transmembrane transport
EML492_06670	COG1653	transport
EML492_06725	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML492_06725	COG2755	lipolytic protein G-D-S-L family
EML492_06730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EML492_06740	COG0525	valine-tRNA ligase activity
EML492_06760	COG0316	Belongs to the HesB IscA family
EML492_06765	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EML492_06770	COG0018	arginyl-trna synthetase
EML492_06780	COG1472	Belongs to the glycosyl hydrolase 3 family
EML492_06785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EML492_06795	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EML492_06800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EML492_06805	COG0805	protein transport
EML492_06810	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EML492_06815	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EML492_06820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EML492_06835	COG1862	Preprotein translocase
EML492_06860	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EML492_06890	COG0544	peptidyl-prolyl cis-trans isomerase activity
EML492_06910	COG2003	Belongs to the UPF0758 family
EML492_06915	COG0024	Methionine aminopeptidase
EML492_06920	COG1489	DNA binding
EML492_06925	COG3243	poly(R)-hydroxyalkanoic acid synthase
EML492_06935	COG0436	Aminotransferase
EML492_07010	COG1278	Cold shock
EML492_07040	COG1280	lysine exporter protein (LysE YggA)
EML492_07045	COG1522	sequence-specific DNA binding
EML492_07055	COG1126	abc transporter atp-binding protein
EML492_07060	COG0765	amino acid transport
EML492_07065	COG4597	amino acid ABC transporter
EML492_07070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_07080	COG0626	cystathionine gamma-synthase activity
EML492_07095	COG0596	Alpha beta hydrolase
EML492_07120	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EML492_07130	COG0537	adenosine 5'-monophosphoramidase activity
EML492_07155	COG0052	Belongs to the universal ribosomal protein uS2 family
EML492_07160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EML492_07165	COG0528	UMP kinase activity
EML492_07170	COG0233	cytoplasmic translational termination
EML492_07175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EML492_07185	COG0750	zinc metalloprotease
EML492_07190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EML492_07195	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EML492_07200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EML492_07205	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EML492_07210	COG3494	Protein of unknown function (DUF1009)
EML492_07215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EML492_07230	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EML492_07240	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EML492_07245	COG0148	phosphopyruvate hydratase activity
EML492_07255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EML492_07260	COG0022	dehydrogenase e1 component
EML492_07260	COG0508	dehydrogenase complex catalyzes the overall conversion of
EML492_07265	COG0508	dehydrogenase complex catalyzes the overall conversion of
EML492_07275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EML492_07290	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EML492_07305	COG2867	negative regulation of translational initiation
EML492_07310	COG1546	Belongs to the CinA family
EML492_07315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EML492_07315	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EML492_07325	COG3852	Histidine kinase
EML492_07330	COG2204	response regulator
EML492_07335	COG5000	phosphorelay sensor kinase activity
EML492_07340	COG2204	response regulator
EML492_07345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EML492_07350	COG1923	regulation of RNA biosynthetic process
EML492_07355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EML492_07360	COG3956	TIGRFAM MazG family protein
EML492_07370	COG1648	precorrin-2 dehydrogenase activity
EML492_07370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EML492_07380	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EML492_07420	COG0785	Cytochrome C biogenesis protein
EML492_07425	COG0679	Auxin Efflux Carrier
EML492_07430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML492_07435	COG1183	phosphatidylcholine synthase activity
EML492_07445	COG3845	ABC transporter
EML492_07450	COG4603	Belongs to the binding-protein-dependent transport system permease family
EML492_07455	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML492_07465	COG1879	ABC-type sugar transport system periplasmic component
EML492_07470	COG1129	ABC transporter
EML492_07475	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_07480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_07485	COG2186	Transcriptional regulator
EML492_07490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EML492_07495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EML492_07515	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EML492_07525	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EML492_07540	COG0583	DNA-binding transcription factor activity
EML492_07565	COG0174	glutamine synthetase
EML492_07570	COG0347	Belongs to the P(II) protein family
EML492_07575	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EML492_07575	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EML492_07585	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EML492_07590	COG0629	single-stranded DNA binding
EML492_07595	COG2095	MarC family integral membrane protein
EML492_07600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EML492_07625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EML492_07640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EML492_07645	COG0343	queuine tRNA-ribosyltransferase activity
EML492_07675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EML492_07690	COG1132	(ABC) transporter
EML492_07695	COG1132	(ABC) transporter
EML492_07700	COG0583	DNA-binding transcription factor activity
EML492_07725	COG0321	lipoyl(octanoyl) transferase activity
EML492_07725	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EML492_07730	COG0084	hydrolase, TatD family'
EML492_07735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML492_07740	COG0730	response to heat
EML492_07750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EML492_07775	COG2094	Belongs to the DNA glycosylase MPG family
EML492_07805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EML492_07810	COG0134	indole-3-glycerol-phosphate synthase activity
EML492_07815	COG0315	cyclic pyranopterin monophosphate synthase activity
EML492_07825	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EML492_07835	COG0372	Belongs to the citrate synthase family
EML492_07840	COG0372	Belongs to the citrate synthase family
EML492_07845	COG0583	DNA-binding transcription factor activity
EML492_07865	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EML492_07880	COG0504	CTP synthase activity
EML492_07885	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EML492_07890	COG0149	triose-phosphate isomerase activity
EML492_07900	COG0187	DNA topoisomerase II activity
EML492_07910	COG0628	permease
EML492_07945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EML492_07955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EML492_07965	COG0302	gtp cyclohydrolase
EML492_07970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EML492_07975	COG1752	Esterase of the alpha-beta hydrolase superfamily
EML492_08000	COG2267	carboxylic ester hydrolase activity
EML492_08015	COG1686	Belongs to the peptidase S11 family
EML492_08035	COG1760	l-serine dehydratase
EML492_08060	COG2239	Acts as a magnesium transporter
EML492_08065	COG0242	peptide deformylase activity
EML492_08080	COG0321	lipoyl(octanoyl) transferase activity
EML492_08095	COG4770	biotin carboxylase activity
EML492_08100	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EML492_08105	COG1671	Belongs to the UPF0178 family
EML492_08110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EML492_08120	COG2259	Doxx family
EML492_08125	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EML492_08140	COG0546	phosphoglycolate phosphatase activity
EML492_08160	COG0509	glycine decarboxylation via glycine cleavage system
EML492_08165	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EML492_08165	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EML492_08175	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EML492_08190	COG0316	Belongs to the HesB IscA family
EML492_08195	COG2151	metal-sulfur cluster biosynthetic enzyme
EML492_08200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EML492_08205	COG0719	Fe-S assembly protein
EML492_08210	COG0396	ATPase activity
EML492_08220	COG0719	Fe-S assembly protein
EML492_08230	COG2945	thiolester hydrolase activity
EML492_08245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EML492_08250	COG0346	lactoylglutathione lyase activity
EML492_08260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EML492_08265	COG2833	Protein of unknown function (DUF455)
EML492_08270	COG0739	heme binding
EML492_08270	COG0741	lytic transglycosylase activity
EML492_08270	COG1196	nuclear chromosome segregation
EML492_08275	COG0513	Belongs to the DEAD box helicase family
EML492_08280	COG1051	belongs to the nudix hydrolase family
EML492_08290	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EML492_08295	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EML492_08295	COG3608	succinylglutamate desuccinylase aspartoacylase
EML492_08310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EML492_08315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML492_08335	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EML492_08355	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EML492_08360	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EML492_08365	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EML492_08370	COG0047	phosphoribosylformylglycinamidine synthase activity
EML492_08390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML492_08400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EML492_08425	COG2814	Major facilitator Superfamily
EML492_08430	COG2814	Major facilitator Superfamily
EML492_08440	COG0483	inositol monophosphate 1-phosphatase activity
EML492_08445	COG0483	inositol monophosphate 1-phosphatase activity
EML492_08450	COG0037	tRNA processing
EML492_08455	COG2066	Belongs to the glutaminase family
EML492_08460	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EML492_08470	COG1304	FMN binding
EML492_08480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EML492_08495	COG0538	isocitrate dehydrogenase activity
EML492_08510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EML492_08515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EML492_08525	COG2313	pseudouridylate synthase activity
EML492_08560	COG3106	COG3106 Predicted ATPase
EML492_08565	COG3768	UPF0283 membrane protein
EML492_08585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EML492_08595	COG0633	Ferredoxin
EML492_08625	COG3507	Belongs to the glycosyl hydrolase 43 family
EML492_08630	COG0667	Aldo Keto reductase
EML492_08635	COG0673	inositol 2-dehydrogenase activity
EML492_08655	COG0395	ABC-type sugar transport system, permease component
EML492_08660	COG1175	transmembrane transport
EML492_08675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EML492_08695	COG1127	ABC transporter
EML492_08700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EML492_08705	COG2814	Major facilitator Superfamily
EML492_08715	COG0280	phosphate acetyltransferase
EML492_08715	COG0281	malic enzyme
EML492_08730	COG0823	Involved in the tonB-independent uptake of proteins
EML492_08740	COG1368	sulfuric ester hydrolase activity
EML492_08765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EML492_08780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EML492_08785	COG0546	phosphoglycolate phosphatase activity
EML492_08790	COG2989	Protein conserved in bacteria
EML492_08795	COG0114	fumarate hydratase activity
EML492_08805	COG3706	GGDEF domain
EML492_08820	COG1846	Transcriptional regulator
EML492_08835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EML492_08845	COG0840	transmembrane signaling receptor activity
EML492_08845	COG2972	Histidine kinase
EML492_08850	COG0697	spore germination
EML492_08855	COG0746	molybdenum cofactor guanylyltransferase activity
EML492_08860	COG1763	Mo-molybdopterin cofactor biosynthetic process
EML492_08870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_08885	COG5425	PFAM Usg family protein
EML492_08900	COG0640	Transcriptional regulator
EML492_08910	COG1116	anion transmembrane transporter activity
EML492_08915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_08920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_08925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_08930	COG2084	Dehydrogenase
EML492_08935	COG1522	sequence-specific DNA binding
EML492_08940	COG1573	uracil-dna glycosylase
EML492_08950	COG2202	Pas domain
EML492_08950	COG2205	protein histidine kinase activity
EML492_08960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EML492_08965	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EML492_08980	COG0697	spore germination
EML492_08995	COG0842	Transport permease protein
EML492_09000	COG1131	(ABC) transporter
EML492_09015	COG1607	acyl-coa hydrolase
EML492_09045	COG2814	Major facilitator Superfamily
EML492_09050	COG0556	nucleotide-excision repair
EML492_09065	COG1278	Cold shock
EML492_09070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EML492_09075	COG0179	Fumarylacetoacetate (FAA) hydrolase
EML492_09090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EML492_09095	COG1121	(ABC) transporter
EML492_09105	COG0523	cobalamin synthesis protein
EML492_09130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EML492_09145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML492_09205	COG1917	Cupin 2, conserved barrel domain protein
EML492_09230	COG1492	cobalamin metabolic process
EML492_09245	COG4176	ABC-type proline glycine betaine transport system permease component
EML492_09250	COG4175	Glycine betaine
EML492_09250	COG0517	IMP dehydrogenase activity
EML492_09255	COG1410	methionine synthase
EML492_09255	COG0646	methionine synthase
EML492_09265	COG0463	Glycosyl transferase, family 2
EML492_09280	COG5598	trimethylamine methyltransferase
EML492_09285	COG5012	cobalamin binding
EML492_09315	COG0646	methionine synthase
EML492_09315	COG1410	methionine synthase
EML492_09335	COG0583	DNA-binding transcription factor activity
EML492_09360	COG0745	RESPONSE REGULATOR receiver
EML492_09365	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EML492_09365	COG3264	Mechanosensitive ion channel
EML492_09390	COG1959	2 iron, 2 sulfur cluster binding
EML492_09405	COG0384	phenazine biosynthesis protein PhzF
EML492_09420	COG3842	ATPase activity
EML492_09435	COG0667	Aldo Keto reductase
EML492_09440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML492_09455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML492_09465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EML492_09475	COG2207	Transcriptional regulator
EML492_09480	COG1064	alcohol dehydrogenase
EML492_09485	COG1252	NADH dehydrogenase
EML492_09495	COG1522	sequence-specific DNA binding
EML492_09500	COG1794	racemase activity, acting on amino acids and derivatives
EML492_09510	COG0456	acetyltransferase
EML492_09520	COG2814	Major facilitator Superfamily
EML492_09525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML492_09530	COG1733	regulation of RNA biosynthetic process
EML492_09540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EML492_09545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EML492_09580	COG0656	L-ascorbic acid biosynthetic process
EML492_09590	COG0440	acetolactate synthase activity
EML492_09595	COG0028	Belongs to the TPP enzyme family
EML492_09605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EML492_09610	COG3830	Belongs to the UPF0237 family
EML492_09610	COG0560	Phosphoserine phosphatase
EML492_09620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EML492_09630	COG0330	HflC and HflK could
EML492_09645	COG0463	Glycosyl transferase, family 2
EML492_09655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EML492_09665	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EML492_09685	COG0410	ABC transporter
EML492_09700	COG0583	DNA-binding transcription factor activity
EML492_09715	COG3238	Protein conserved in bacteria
EML492_09725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EML492_09755	COG0277	FAD linked oxidase domain protein
EML492_09760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_09765	COG0765	amino acid transport
EML492_09770	COG0765	amino acid transport
EML492_09790	COG2885	chlorophyll binding
EML492_09795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EML492_09800	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML492_09805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_09810	COG0210	DNA helicase
EML492_09825	COG1335	isochorismatase
EML492_09840	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EML492_09845	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EML492_09865	COG0006	proline dipeptidase activity
EML492_09875	COG2264	protein methyltransferase activity
EML492_09885	COG1999	signal sequence binding
EML492_09890	COG0835	chemotaxis
EML492_09905	COG1247	-acetyltransferase
EML492_09910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EML492_09920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EML492_09930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EML492_09935	COG0849	cell division
EML492_09940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EML492_09945	COG1181	Belongs to the D-alanine--D-alanine ligase family
EML492_09950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EML492_09955	COG0477	Major facilitator Superfamily
EML492_09960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EML492_09965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EML492_09970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EML492_09980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EML492_09985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EML492_09995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EML492_10010	COG0275	rRNA processing
EML492_10015	COG2001	Belongs to the MraZ family
EML492_10035	COG3023	N-Acetylmuramoyl-L-alanine amidase
EML492_10050	COG1280	lysine exporter protein (LysE YggA)
EML492_10070	COG4106	trans-aconitate 2-methyltransferase activity
EML492_10085	COG0697	spore germination
EML492_10095	COG2226	methyltransferase
EML492_10120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EML492_10125	COG0028	Belongs to the TPP enzyme family
EML492_10130	COG0251	oxidation-reduction process
EML492_10145	COG1376	ErfK ybiS ycfS ynhG family protein
EML492_10155	COG1012	belongs to the aldehyde dehydrogenase family
EML492_10160	COG0174	glutamine synthetase
EML492_10190	COG2011	ABC-type metal ion transport system permease component
EML492_10195	COG3842	ATPase activity
EML492_10200	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EML492_10210	COG1609	Transcriptional regulator
EML492_10220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EML492_10230	COG0673	inositol 2-dehydrogenase activity
EML492_10235	COG0395	ABC-type sugar transport system, permease component
EML492_10240	COG1175	transmembrane transport
EML492_10250	COG2971	BadF BadG BcrA BcrD
EML492_10255	COG2188	Transcriptional regulator
EML492_10270	COG4702	Belongs to the UPF0303 family
EML492_10285	COG0438	transferase activity, transferring glycosyl groups
EML492_10340	COG2264	protein methyltransferase activity
EML492_10390	COG2968	Membrane
EML492_10405	COG0432	Pfam Uncharacterised protein family UPF0047
EML492_10410	COG5507	3-demethylubiquinone-9 3-methyltransferase
EML492_10430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML492_10430	COG0072	phenylalanine-tRNA ligase activity
EML492_10435	COG1917	Cupin 2, conserved barrel domain protein
EML492_10435	COG2207	Transcriptional regulator
EML492_10455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EML492_10460	COG1063	alcohol dehydrogenase
EML492_10470	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_10475	COG0514	ATP-dependent DNA helicase (RecQ)
EML492_10480	COG0358	DNA primase activity
EML492_10495	COG0505	Belongs to the CarA family
EML492_10505	COG0534	Mate efflux family protein
EML492_10515	COG2321	neutral zinc metallopeptidase
EML492_10530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EML492_10535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EML492_10555	COG1522	sequence-specific DNA binding
EML492_10560	COG0492	ferredoxin-NADP+ reductase activity
EML492_10565	COG0583	DNA-binding transcription factor activity
EML492_10575	COG1902	pentaerythritol trinitrate reductase activity
EML492_10585	COG0300	oxidoreductase activity
EML492_10590	COG0583	DNA-binding transcription factor activity
EML492_10600	COG0387	Pfam Sodium calcium exchanger
EML492_10610	COG2133	pyrroloquinoline quinone binding
EML492_10620	COG1278	Cold shock
EML492_10630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML492_10645	COG1846	Transcriptional regulator
EML492_10650	COG0745	RESPONSE REGULATOR receiver
EML492_10655	COG2205	protein histidine kinase activity
EML492_10665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML492_10685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EML492_10695	COG1496	oxidoreductase activity
EML492_10710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EML492_10730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EML492_10745	COG0193	aminoacyl-tRNA hydrolase activity
EML492_10755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EML492_10775	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EML492_10780	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EML492_10780	COG2857	Cytochrome c1
EML492_10800	COG1132	(ABC) transporter
EML492_10805	COG1132	(ABC) transporter
EML492_10810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EML492_10830	COG0408	coproporphyrinogen oxidase activity
EML492_10845	COG0617	tRNA 3'-terminal CCA addition
EML492_10860	COG0714	Associated with various cellular activities
EML492_10880	COG0454	-acetyltransferase
EML492_10895	COG0435	Glutathione S-transferase
EML492_10935	COG1132	(ABC) transporter
EML492_10940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EML492_10945	COG3135	benzoate transporter
EML492_10950	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EML492_10960	COG0740	serine-type endopeptidase activity
EML492_10970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EML492_10975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EML492_10980	COG0778	Nitroreductase
EML492_10990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EML492_10990	COG0512	Glutamine amidotransferase of anthranilate synthase
EML492_10995	COG0488	(ABC) transporter
EML492_11010	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EML492_11015	COG2862	Uncharacterized protein family, UPF0114
EML492_11030	COG2197	response regulator
EML492_11055	COG1435	thymidine kinase activity
EML492_11065	COG4176	ABC-type proline glycine betaine transport system permease component
EML492_11070	COG4175	Glycine betaine
EML492_11085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML492_11090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EML492_11095	COG0366	Alpha amylase catalytic
EML492_11105	COG0601	transmembrane transport
EML492_11110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_11120	COG4608	Belongs to the ABC transporter superfamily
EML492_11125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_11145	COG1846	Transcriptional regulator
EML492_11150	COG1160	GTP binding
EML492_11170	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EML492_11180	COG0024	Methionine aminopeptidase
EML492_11200	COG4941	Belongs to the sigma-70 factor family
EML492_11205	COG3795	YCII-related domain
EML492_11215	COG1619	proteins homologs of microcin C7 resistance protein MccF
EML492_11225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML492_11230	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_11240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML492_11250	COG0583	DNA-binding transcription factor activity
EML492_11265	COG0402	S-adenosylhomocysteine deaminase activity
EML492_11280	COG2351	hydroxyisourate hydrolase activity
EML492_11285	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EML492_11295	COG3648	Uricase
EML492_11295	COG3195	allantoin biosynthetic process
EML492_11305	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EML492_11310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_11315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_11315	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EML492_11320	COG0784	Response regulator, receiver
EML492_11320	COG5002	protein histidine kinase activity
EML492_11320	COG2205	protein histidine kinase activity
EML492_11325	COG5598	trimethylamine methyltransferase
EML492_11335	COG0513	Belongs to the DEAD box helicase family
EML492_11350	COG2308	Evidence 4 Homologs of previously reported genes of
EML492_11370	COG1132	(ABC) transporter
EML492_11375	COG0129	dihydroxy-acid dehydratase activity
EML492_11380	COG1012	belongs to the aldehyde dehydrogenase family
EML492_11390	COG4214	carbohydrate transport
EML492_11420	COG0673	inositol 2-dehydrogenase activity
EML492_11430	COG4213	ABC transporter substrate-binding protein
EML492_11435	COG4214	carbohydrate transport
EML492_11440	COG1129	ABC transporter
EML492_11480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EML492_11500	COG0671	phosphoesterase, PA-phosphatase related
EML492_11510	COG2194	sulfuric ester hydrolase activity
EML492_11535	COG0406	alpha-ribazole phosphatase activity
EML492_11580	COG0022	dehydrogenase e1 component
EML492_11590	COG0038	chloride channel
EML492_11610	COG2076	Multidrug Resistance protein
EML492_11620	COG3842	ATPase activity
EML492_11625	COG3833	ABC-type maltose transport systems, permease component
EML492_11645	COG0673	inositol 2-dehydrogenase activity
EML492_11650	COG1609	Transcriptional regulator
EML492_11700	COG4558	Periplasmic binding protein
EML492_11705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML492_11710	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EML492_11735	COG0784	Response regulator, receiver
EML492_11740	COG2202	Pas domain
EML492_11740	COG3920	Histidine kinase
EML492_11745	COG0493	'glutamate synthase
EML492_11755	COG1309	transcriptional regulator
EML492_11785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_11790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_11795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_11800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_11810	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EML492_11815	COG0830	nickel cation binding
EML492_11820	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EML492_11825	COG3706	GGDEF domain
EML492_11835	COG0804	urea catabolic process
EML492_11840	COG1442	glycosyl transferase family 8
EML492_11845	COG0832	Belongs to the urease beta subunit family
EML492_11850	COG0831	urea catabolic process
EML492_11855	COG0829	nickel cation binding
EML492_11865	COG0411	ABC transporter
EML492_11875	COG0559	Belongs to the binding-protein-dependent transport system permease family
EML492_11885	COG2198	Histidine kinase
EML492_11885	COG0784	Response regulator, receiver
EML492_11885	COG5002	protein histidine kinase activity
EML492_11890	COG0745	RESPONSE REGULATOR receiver
EML492_11895	COG0683	leucine binding
EML492_11930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_11935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_11935	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML492_11940	COG4311	Sarcosine oxidase, delta subunit
EML492_11945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_12005	COG0564	pseudouridine synthase activity
EML492_12010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EML492_12020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EML492_12030	COG0402	S-adenosylhomocysteine deaminase activity
EML492_12035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EML492_12040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML492_12045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML492_12060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_12070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_12075	COG0402	S-adenosylhomocysteine deaminase activity
EML492_12085	COG2249	NAD(P)H dehydrogenase (quinone) activity
EML492_12110	COG0251	oxidation-reduction process
EML492_12135	COG0346	lactoylglutathione lyase activity
EML492_12140	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EML492_12145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML492_12160	COG1349	DNA-binding transcription factor activity
EML492_12165	COG0583	DNA-binding transcription factor activity
EML492_12170	COG2855	membrane
EML492_12175	COG3300	MHYT domain
EML492_12175	COG5001	Diguanylate cyclase
EML492_12180	COG0129	dihydroxy-acid dehydratase activity
EML492_12185	COG2084	Dehydrogenase
EML492_12190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML492_12210	COG0583	DNA-binding transcription factor activity
EML492_12220	COG1595	DNA-templated transcription, initiation
EML492_12230	COG0697	spore germination
EML492_12240	COG1846	Transcriptional regulator
EML492_12260	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EML492_12265	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_12270	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_12315	COG0477	Major facilitator Superfamily
EML492_12325	COG1278	Cold shock
EML492_12335	COG0346	lactoylglutathione lyase activity
EML492_12345	COG4948	Mandelate Racemase Muconate Lactonizing
EML492_12380	COG2011	ABC-type metal ion transport system permease component
EML492_12390	COG4521	taurine ABC transporter
EML492_12400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_12405	COG0330	HflC and HflK could
EML492_12410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_12420	COG2814	Major facilitator Superfamily
EML492_12455	COG0482	sulfurtransferase activity
EML492_12470	COG4589	Belongs to the CDS family
EML492_12480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_12520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EML492_12525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EML492_12530	COG0037	tRNA processing
EML492_12540	COG2885	chlorophyll binding
EML492_12545	COG0823	Involved in the tonB-independent uptake of proteins
EML492_12570	COG0824	Thioesterase
EML492_12585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EML492_12590	COG1268	BioY protein
EML492_12595	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EML492_12600	COG2318	DinB family
EML492_12605	COG0494	nUDIX hydrolase
EML492_12610	COG1408	metallophosphoesterase
EML492_12615	COG2255	four-way junction helicase activity
EML492_12620	COG0632	four-way junction helicase activity
EML492_12635	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EML492_12640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_12645	COG0217	transcriptional regulatory protein
EML492_12655	COG1692	metallophosphoesterase
EML492_12665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML492_12690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML492_12700	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_12705	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_12755	COG0126	phosphoglycerate kinase activity
EML492_12760	COG3588	fructose-bisphosphate aldolase
EML492_12765	COG0384	phenazine biosynthesis protein PhzF
EML492_12795	COG0254	rRNA binding
EML492_12805	COG3422	double-strand break repair
EML492_12830	COG0483	inositol monophosphate 1-phosphatase activity
EML492_12860	COG0640	Transcriptional regulator
EML492_12875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EML492_12880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EML492_12885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EML492_12890	COG0457	Tetratricopeptide repeat
EML492_12895	COG0596	Alpha beta hydrolase
EML492_12900	COG0583	DNA-binding transcription factor activity
EML492_12925	COG1280	lysine exporter protein (LysE YggA)
EML492_12930	COG0469	pyruvate kinase activity
EML492_12950	COG3750	Belongs to the UPF0335 family
EML492_12975	COG1999	signal sequence binding
EML492_12980	COG2372	response to copper ion
EML492_12985	COG0726	polysaccharide deacetylase
EML492_13005	COG3108	Peptidase M15
EML492_13020	COG0512	Glutamine amidotransferase of anthranilate synthase
EML492_13020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EML492_13040	COG5310	Homospermidine synthase
EML492_13055	COG0737	Belongs to the 5'-nucleotidase family
EML492_13060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EML492_13065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EML492_13070	COG0330	HflC and HflK could
EML492_13080	COG0517	IMP dehydrogenase activity
EML492_13080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EML492_13090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EML492_13095	COG2951	lytic endotransglycosylase activity
EML492_13115	COG0069	glutamate synthase activity
EML492_13115	COG0067	glutamate synthase
EML492_13115	COG0070	glutamate synthase
EML492_13135	COG0071	Belongs to the small heat shock protein (HSP20) family
EML492_13145	COG1522	sequence-specific DNA binding
EML492_13155	COG0454	-acetyltransferase
EML492_13160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EML492_13215	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EML492_13215	COG0662	Cupin 2, conserved barrel domain protein
EML492_13225	COG2308	Evidence 4 Homologs of previously reported genes of
EML492_13225	COG2307	Protein conserved in bacteria
EML492_13240	COG0058	SHG alpha-glucan phosphorylase activity
EML492_13245	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EML492_13250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EML492_13255	COG0297	glycogen (starch) synthase activity
EML492_13260	COG0033	Phosphoglucomutase
EML492_13265	COG1523	belongs to the glycosyl hydrolase 13 family
EML492_13280	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML492_13280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_13305	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EML492_13315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_13320	COG3920	Histidine kinase
EML492_13320	COG2202	Pas domain
EML492_13345	COG5001	Diguanylate cyclase
EML492_13350	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EML492_13355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EML492_13360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML492_13365	COG1609	Transcriptional regulator
EML492_13370	COG1846	Transcriptional regulator
EML492_13380	COG0523	cobalamin synthesis protein
EML492_13390	COG1045	serine acetyltransferase
EML492_13415	COG0583	DNA-binding transcription factor activity
EML492_13425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EML492_13440	COG0800	Aldolase
EML492_13445	COG2954	triphosphatase activity
EML492_13455	COG1054	Belongs to the UPF0176 family
EML492_13465	COG0431	NADPH-dependent FMN reductase
EML492_13480	COG0673	inositol 2-dehydrogenase activity
EML492_13490	COG1879	ABC-type sugar transport system periplasmic component
EML492_13495	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_13505	COG1609	Transcriptional regulator
EML492_13515	COG2115	Belongs to the xylose isomerase family
EML492_13520	COG1070	Carbohydrate kinase
EML492_13525	COG1609	Transcriptional regulator
EML492_13550	COG1253	flavin adenine dinucleotide binding
EML492_13560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EML492_13565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EML492_13570	COG0673	inositol 2-dehydrogenase activity
EML492_13575	COG1082	Xylose isomerase domain protein TIM barrel
EML492_13580	COG1082	Xylose isomerase domain protein TIM barrel
EML492_13600	COG0583	DNA-binding transcription factor activity
EML492_13605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EML492_13610	COG3842	ATPase activity
EML492_13615	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_13620	COG1177	transmembrane transport
EML492_13640	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_13660	COG3254	rhamnose metabolic process
EML492_13665	COG4948	Mandelate Racemase Muconate Lactonizing
EML492_13670	COG3842	ATPase activity
EML492_13675	COG0395	ABC-type sugar transport system, permease component
EML492_13680	COG1175	transmembrane transport
EML492_13710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EML492_13730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EML492_13740	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EML492_13760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML492_13775	COG0395	ABC-type sugar transport system, permease component
EML492_13780	COG1175	transmembrane transport
EML492_13790	COG2390	Transcriptional regulator
EML492_13810	COG1940	carbohydrate kinase activity
EML492_13815	COG3142	Participates in the control of copper homeostasis
EML492_13830	COG2719	SpoVR family
EML492_13835	COG2718	Belongs to the UPF0229 family
EML492_13840	COG2766	serine protein kinase
EML492_13855	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EML492_13860	COG0424	maF-like protein
EML492_13865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EML492_13875	COG5328	Belongs to the UPF0262 family
EML492_13880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EML492_13890	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EML492_13910	COG1196	nuclear chromosome segregation
EML492_13930	COG2514	catechol 2,3-dioxygenase activity
EML492_13935	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EML492_13945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_13965	COG1764	response to oxidative stress
EML492_13970	COG2186	Transcriptional regulator
EML492_13975	COG4948	Mandelate Racemase Muconate Lactonizing
EML492_13980	COG0670	Belongs to the BI1 family
EML492_13995	COG3781	membrane
EML492_14000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EML492_14005	COG2900	Belongs to the SlyX family
EML492_14015	COG3842	ATPase activity
EML492_14020	COG1175	transmembrane transport
EML492_14035	COG1609	Transcriptional regulator
EML492_14090	COG1396	sequence-specific DNA binding
EML492_14115	COG0784	Response regulator, receiver
EML492_14115	COG4191	Histidine kinase
EML492_14135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML492_14140	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EML492_14155	COG4221	oxidoreductase activity
EML492_14160	COG4191	Histidine kinase
EML492_14165	COG4566	intracellular signal transduction
EML492_14170	COG4566	intracellular signal transduction
EML492_14175	COG4566	intracellular signal transduction
EML492_14180	COG0583	DNA-binding transcription factor activity
EML492_14185	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_14230	COG2205	protein histidine kinase activity
EML492_14240	COG1187	pseudouridine synthase activity
EML492_14250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EML492_14275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EML492_14280	COG0443	Heat shock 70 kDa protein
EML492_14285	COG0484	heat shock protein binding
EML492_14290	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EML492_14305	COG2226	methyltransferase
EML492_14325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_14340	COG3474	cytochrome
EML492_14345	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EML492_14350	COG0077	Prephenate dehydratase
EML492_14350	COG1605	Chorismate mutase
EML492_14365	COG2378	regulation of single-species biofilm formation
EML492_14370	COG2816	NAD+ diphosphatase activity
EML492_14385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EML492_14390	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EML492_14395	COG1522	sequence-specific DNA binding
EML492_14410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EML492_14415	COG2951	lytic endotransglycosylase activity
EML492_14420	COG0779	Required for maturation of 30S ribosomal subunits
EML492_14435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EML492_14440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EML492_14445	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EML492_14450	COG2267	carboxylic ester hydrolase activity
EML492_14455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EML492_14460	COG1185	polyribonucleotide nucleotidyltransferase activity
EML492_14475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EML492_14480	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EML492_14490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EML492_14500	COG2860	membrane
EML492_14540	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EML492_14545	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EML492_14550	COG0539	negative regulation of cytoplasmic translation
EML492_14570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EML492_14575	COG1012	belongs to the aldehyde dehydrogenase family
EML492_14580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EML492_14585	COG2372	response to copper ion
EML492_14590	COG1276	copper resistance
EML492_14595	COG3622	Belongs to the hyi family
EML492_14615	COG0395	ABC-type sugar transport system, permease component
EML492_14645	COG1082	Xylose isomerase domain protein TIM barrel
EML492_14650	COG0673	inositol 2-dehydrogenase activity
EML492_14660	COG1129	ABC transporter
EML492_14665	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_14680	COG0673	inositol 2-dehydrogenase activity
EML492_14690	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_14700	COG3962	Belongs to the TPP enzyme family
EML492_14705	COG0673	inositol 2-dehydrogenase activity
EML492_14710	COG1012	belongs to the aldehyde dehydrogenase family
EML492_14785	COG4372	Transposase
EML492_14790	COG3436	PFAM IS66 Orf2 family protein
EML492_14885	COG0542	response to heat
EML492_14895	COG2890	protein-(glutamine-N5) methyltransferase activity
EML492_14900	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EML492_14910	COG0527	aspartate kinase activity
EML492_14915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML492_14930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EML492_14940	COG1040	competence protein
EML492_14945	COG2226	methyltransferase
EML492_14960	COG0494	nUDIX hydrolase
EML492_14970	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EML492_14975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EML492_14980	COG0653	protein targeting
EML492_14985	COG0583	DNA-binding transcription factor activity
EML492_14990	COG1942	4-Oxalocrotonate Tautomerase
EML492_14995	COG0625	glutathione transferase activity
EML492_15010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML492_15025	COG0681	Belongs to the peptidase S26 family
EML492_15030	COG0667	Aldo Keto reductase
EML492_15035	COG2264	protein methyltransferase activity
EML492_15055	COG4977	sequence-specific DNA binding
EML492_15055	COG1917	Cupin 2, conserved barrel domain protein
EML492_15090	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EML492_15095	COG1295	ribonuclease BN
EML492_15100	COG0300	oxidoreductase activity
EML492_15115	COG2086	electron transfer activity
EML492_15125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EML492_15130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EML492_15135	COG0165	Argininosuccinate lyase
EML492_15170	COG2884	Cell division ATP-binding protein ftsE
EML492_15190	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EML492_15210	COG0287	Prephenate dehydrogenase
EML492_15215	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EML492_15220	COG2226	methyltransferase
EML492_15225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EML492_15235	COG2382	esterase
EML492_15250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EML492_15285	COG4536	flavin adenine dinucleotide binding
EML492_15290	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EML492_15295	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EML492_15305	COG4974	Belongs to the 'phage' integrase family
EML492_15310	COG0825	malonyl-CoA metabolic process
EML492_15315	COG3034	peptidoglycan biosynthetic process
EML492_15325	COG0523	cobalamin synthesis protein
EML492_15330	COG1686	Belongs to the peptidase S11 family
EML492_15365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EML492_15375	COG0156	8-amino-7-oxononanoate synthase activity
EML492_15400	COG0729	surface antigen
EML492_15425	COG0010	Belongs to the arginase family
EML492_15430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EML492_15435	COG0835	chemotaxis
EML492_15440	COG2223	nitrite transmembrane transporter activity
EML492_15450	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EML492_15455	COG3383	formate dehydrogenase (NAD+) activity
EML492_15480	COG0640	Transcriptional regulator
EML492_15485	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_15515	COG4948	Mandelate Racemase Muconate Lactonizing
EML492_15520	COG1012	belongs to the aldehyde dehydrogenase family
EML492_15525	COG1454	alcohol dehydrogenase
EML492_15535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EML492_15540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EML492_15545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EML492_15550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EML492_15555	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EML492_15590	COG4974	Belongs to the 'phage' integrase family
EML492_15605	COG0612	Peptidase, M16
EML492_15615	COG1280	lysine exporter protein (LysE YggA)
EML492_15620	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_15635	COG0508	dehydrogenase complex catalyzes the overall conversion of
EML492_15650	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EML492_15655	COG0045	succinate-CoA ligase (ADP-forming) activity
EML492_15660	COG0039	L-malate dehydrogenase activity
EML492_15665	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EML492_15700	COG2264	protein methyltransferase activity
EML492_15710	COG2350	Protein conserved in bacteria
EML492_15715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EML492_15720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EML492_15725	COG0181	hydroxymethylbilane synthase activity
EML492_15770	COG1872	DUF167
EML492_15775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EML492_15785	COG1217	gtp-binding protein TYPA
EML492_15790	COG0339	signal peptide processing
EML492_15805	COG0137	argininosuccinate synthase activity
EML492_15815	COG1280	lysine exporter protein (LysE YggA)
EML492_15825	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EML492_15840	COG2154	pterin-4-alpha-carbinolamine dehydratase
EML492_15845	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EML492_15850	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EML492_15860	COG4181	ATPase activity
EML492_15870	COG0670	Belongs to the BI1 family
EML492_15895	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EML492_15900	COG4133	protoheme IX ABC transporter activity
EML492_15905	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EML492_15910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EML492_15930	COG2917	probably involved in intracellular septation
EML492_15935	COG0552	protein localization to endoplasmic reticulum
EML492_15940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EML492_15945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EML492_15965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EML492_15970	COG1605	Chorismate mutase
EML492_15970	COG0287	Prephenate dehydrogenase
EML492_15975	COG0228	four-way junction DNA binding
EML492_15980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EML492_15985	COG0336	Belongs to the RNA methyltransferase TrmD family
EML492_16015	COG1522	sequence-specific DNA binding
EML492_16025	COG0110	maltose O-acetyltransferase activity
EML492_16030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EML492_16035	COG0335	large ribosomal subunit rRNA binding
EML492_16045	COG0765	amino acid transport
EML492_16050	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EML492_16055	COG0697	spore germination
EML492_16060	COG1846	Transcriptional regulator
EML492_16080	COG0656	L-ascorbic acid biosynthetic process
EML492_16090	COG0745	RESPONSE REGULATOR receiver
EML492_16105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EML492_16110	COG1674	ftsk spoiiie
EML492_16115	COG0004	ammonium transporteR
EML492_16120	COG0347	Belongs to the P(II) protein family
EML492_16125	COG1946	Acyl-CoA thioesterase
EML492_16130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML492_16135	COG1733	regulation of RNA biosynthetic process
EML492_16145	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_16150	COG2835	tetraacyldisaccharide 4'-kinase activity
EML492_16160	COG3118	belongs to the thioredoxin family
EML492_16185	COG0395	ABC-type sugar transport system, permease component
EML492_16190	COG1175	transmembrane transport
EML492_16200	COG3250	beta-galactosidase activity
EML492_16205	COG1609	Transcriptional regulator
EML492_16225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_16235	COG0745	RESPONSE REGULATOR receiver
EML492_16240	COG2205	protein histidine kinase activity
EML492_16290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EML492_16295	COG2076	Multidrug Resistance protein
EML492_16305	COG1647	Serine aminopeptidase, S33
EML492_16315	COG2076	Multidrug Resistance protein
EML492_16325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EML492_16330	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EML492_16345	COG3618	amidohydrolase
EML492_16350	COG2814	Major facilitator Superfamily
EML492_16355	COG2188	Transcriptional regulator
EML492_16360	COG0583	DNA-binding transcription factor activity
EML492_16370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML492_16375	COG0697	spore germination
EML492_16385	COG1309	transcriptional regulator
EML492_16405	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EML492_16420	COG0438	transferase activity, transferring glycosyl groups
EML492_16455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_16460	COG1116	anion transmembrane transporter activity
EML492_16465	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_16475	COG1396	sequence-specific DNA binding
EML492_16510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_16515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML492_16525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML492_16580	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EML492_16595	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EML492_16600	COG2986	histidine ammonia-lyase
EML492_16605	COG1228	amidohydrolase
EML492_16610	COG0402	S-adenosylhomocysteine deaminase activity
EML492_16615	COG2188	Transcriptional regulator
EML492_16625	COG2986	histidine ammonia-lyase
EML492_16645	COG0025	NhaP-type Na H and K H
EML492_16675	COG1321	iron dependent repressor
EML492_16680	COG1914	H( )-stimulated, divalent metal cation uptake system
EML492_16685	COG0739	heme binding
EML492_16700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML492_16705	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EML492_16710	COG2080	2 iron, 2 sulfur cluster binding
EML492_16715	COG1309	transcriptional regulator
EML492_16725	COG3842	ATPase activity
EML492_16730	COG0395	ABC-type sugar transport system, permease component
EML492_16735	COG1175	transmembrane transport
EML492_16775	COG3842	ATPase activity
EML492_16785	COG0395	ABC-type sugar transport system, permease component
EML492_16800	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EML492_16805	COG2182	Extracellular solute-binding protein
EML492_16820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_16830	COG0673	inositol 2-dehydrogenase activity
EML492_16840	COG0673	inositol 2-dehydrogenase activity
EML492_16845	COG1309	transcriptional regulator
EML492_16855	COG1175	transmembrane transport
EML492_16860	COG0395	ABC-type sugar transport system, permease component
EML492_16865	COG0673	inositol 2-dehydrogenase activity
EML492_16870	COG0673	inositol 2-dehydrogenase activity
EML492_16890	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EML492_16900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML492_16905	COG1509	lysine 2,3-aminomutase activity
EML492_16910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EML492_16915	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EML492_16940	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EML492_16965	COG2188	Transcriptional regulator
EML492_16970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EML492_16975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EML492_16990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_16995	COG0488	(ABC) transporter
EML492_17010	COG2814	Major facilitator Superfamily
EML492_17025	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EML492_17040	COG1329	Transcriptional regulator
EML492_17045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EML492_17080	COG0183	Belongs to the thiolase family
EML492_17085	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
EML492_17090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EML492_17100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EML492_17105	COG0142	geranyltranstransferase activity
EML492_17115	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EML492_17120	COG2223	nitrite transmembrane transporter activity
EML492_17125	COG0697	spore germination
EML492_17140	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_17145	COG0583	DNA-binding transcription factor activity
EML492_17150	COG0662	Cupin 2, conserved barrel domain protein
EML492_17165	COG0740	serine-type endopeptidase activity
EML492_17170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_17175	COG0765	amino acid transport
EML492_17180	COG1126	abc transporter atp-binding protein
EML492_17185	COG0259	pyridoxamine-phosphate oxidase activity
EML492_17195	COG2186	Transcriptional regulator
EML492_17205	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EML492_17215	COG1132	(ABC) transporter
EML492_17230	COG3459	Glycosyltransferase 36 associated
EML492_17255	COG0444	Belongs to the ABC transporter superfamily
EML492_17260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_17265	COG0601	transmembrane transport
EML492_17280	COG1280	lysine exporter protein (LysE YggA)
EML492_17285	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EML492_17365	COG4211	Belongs to the binding-protein-dependent transport system permease family
EML492_17370	COG1129	ABC transporter
EML492_17420	COG3038	cytochrome b561
EML492_17435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EML492_17445	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EML492_17450	COG2948	multi-organism process
EML492_17455	COG3504	Conjugal transfer protein
EML492_17460	COG3736	Type IV secretory pathway, component VirB8
EML492_17470	COG3704	protein secretion by the type IV secretion system
EML492_17485	COG3451	type IV secretory pathway VirB4
EML492_17490	COG3702	type iv secretory pathway
EML492_17495	COG3838	Conjugal transfer protein Trbc
EML492_17515	COG0745	RESPONSE REGULATOR receiver
EML492_17520	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_17525	COG0028	Belongs to the TPP enzyme family
EML492_17530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EML492_17540	COG3842	ATPase activity
EML492_17545	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_17550	COG1177	transmembrane transport
EML492_17580	COG0745	RESPONSE REGULATOR receiver
EML492_17615	COG3505	Type IV secretory pathway VirD4
EML492_17625	COG2226	methyltransferase
EML492_17640	COG0438	transferase activity, transferring glycosyl groups
EML492_17660	COG2813	Specifically methylates the guanine in position
EML492_17690	COG0662	Cupin 2, conserved barrel domain protein
EML492_17690	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EML492_17730	COG3220	belongs to the UPF0276 family
EML492_17770	COG4650	regulator
EML492_17815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EML492_17820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EML492_17835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EML492_17840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EML492_17845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EML492_17850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EML492_17855	COG0725	ABC transporter, periplasmic molybdate-binding protein
EML492_17860	COG4149	molybdate abc transporter
EML492_17865	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EML492_17870	COG2005	Transcriptional regulator
EML492_17870	COG3585	molybdate ion transport
EML492_17875	COG0799	negative regulation of ribosome biogenesis
EML492_17880	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EML492_17890	COG0793	Belongs to the peptidase S41A family
EML492_17900	COG0494	nUDIX hydrolase
EML492_17915	COG0587	DNA-directed DNA polymerase activity
EML492_17935	COG2301	Belongs to the HpcH HpaI aldolase family
EML492_17945	COG0066	3-isopropylmalate dehydratase activity
EML492_17955	COG0473	3-isopropylmalate dehydrogenase activity
EML492_17960	COG0671	phosphoesterase, PA-phosphatase related
EML492_17970	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_17975	COG0783	Belongs to the Dps family
EML492_17985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EML492_17995	COG0288	reversible hydration of carbon dioxide
EML492_18005	COG2902	Dehydrogenase
EML492_18010	COG2270	Major facilitator Superfamily
EML492_18015	COG0138	bifunctional purine biosynthesis protein purh
EML492_18025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EML492_18025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EML492_18030	COG0501	Belongs to the peptidase M48B family
EML492_18040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML492_18055	COG0495	leucyl-tRNA aminoacylation
EML492_18080	COG0357	Ribosomal RNA small subunit methyltransferase G
EML492_18085	COG0445	tRNA wobble uridine modification
EML492_18090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EML492_18095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EML492_18100	COG1981	membrane
EML492_18105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EML492_18110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EML492_18115	COG0424	maF-like protein
EML492_18120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EML492_18125	COG0237	dephospho-CoA kinase activity
EML492_18140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EML492_18155	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EML492_18210	COG0135	phosphoribosylanthranilate isomerase activity
EML492_18215	COG0133	tryptophan synthase activity
EML492_18220	COG0159	tryptophan synthase activity
EML492_18225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EML492_18240	COG1074	ATP-dependent DNA helicase activity
EML492_18250	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EML492_18255	COG3178	'Phosphotransferase
EML492_18260	COG2205	protein histidine kinase activity
EML492_18265	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EML492_18270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML492_18275	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML492_18275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EML492_18285	COG0642	Histidine kinase
EML492_18290	COG0745	RESPONSE REGULATOR receiver
EML492_18295	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EML492_18315	COG1072	(Pantothenic acid kinase))
EML492_18320	COG0140	phosphoribosyl-ATP diphosphatase activity
EML492_18325	COG0107	imidazoleglycerol-phosphate synthase activity
EML492_18330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EML492_18335	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EML492_18345	COG0131	Imidazoleglycerol-phosphate dehydratase
EML492_18350	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EML492_18355	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EML492_18375	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EML492_18395	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EML492_18405	COG1643	Atp-dependent helicase
EML492_18410	COG2423	ornithine cyclodeaminase activity
EML492_18445	COG2972	Histidine kinase
EML492_18445	COG0840	transmembrane signaling receptor activity
EML492_18450	COG3842	ATPase activity
EML492_18460	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_18470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EML492_18480	COG2199	diguanylate cyclase activity
EML492_18480	COG2200	EAL domain
EML492_18490	COG4957	zinc ion binding
EML492_18495	COG0306	phosphate transporter
EML492_18530	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EML492_18535	COG1845	cytochrome c oxidase, subunit III
EML492_18540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EML492_18545	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EML492_18550	COG0477	Major facilitator Superfamily
EML492_18565	COG3842	ATPase activity
EML492_18570	COG1473	amidohydrolase
EML492_18575	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EML492_18585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_18590	COG5001	Diguanylate cyclase
EML492_18590	COG3300	MHYT domain
EML492_18600	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EML492_18600	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EML492_18605	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EML492_18610	COG3454	Phosphonate metabolism
EML492_18615	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EML492_18620	COG3639	organic phosphonate transmembrane transporter activity
EML492_18635	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EML492_18650	COG4778	phosphonate C-P lyase system protein PhnL
EML492_18655	COG4107	phosphonate C-P lyase system protein PhnK
EML492_18660	COG3627	carbon phosphorus lyase activity
EML492_18665	COG3626	phosphonate metabolism
EML492_18670	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EML492_18675	COG3624	Phosphonate C-P lyase system protein PhnG
EML492_18680	COG2188	Transcriptional regulator
EML492_18685	COG0588	phosphoglycerate mutase activity
EML492_18690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EML492_18695	COG1132	(ABC) transporter
EML492_18700	COG0837	glucose binding
EML492_18705	COG1803	Methylglyoxal synthase
EML492_18710	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EML492_18720	COG4166	transmembrane transport
EML492_18725	COG4174	ABC transporter (Permease)
EML492_18730	COG4239	(ABC) transporter, permease
EML492_18735	COG4172	Belongs to the ABC transporter superfamily
EML492_18740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_18745	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EML492_18765	COG0668	transmembrane transport
EML492_18780	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_18785	COG1902	pentaerythritol trinitrate reductase activity
EML492_18790	COG2267	carboxylic ester hydrolase activity
EML492_18820	COG0583	DNA-binding transcription factor activity
EML492_18830	COG2814	Major facilitator Superfamily
EML492_18840	COG0667	Aldo Keto reductase
EML492_18845	COG0583	DNA-binding transcription factor activity
EML492_18945	COG1744	ABC transporter substrate-binding protein PnrA-like
EML492_18950	COG3845	ABC transporter
EML492_18955	COG4603	Belongs to the binding-protein-dependent transport system permease family
EML492_18960	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML492_18970	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EML492_18975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EML492_18980	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EML492_18990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EML492_18995	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EML492_19000	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EML492_19035	COG4964	Belongs to the GSP D family
EML492_19075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EML492_19095	COG0154	amidase activity
EML492_19100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_19110	COG0747	negative chemotaxis
EML492_19130	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EML492_19150	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EML492_19175	COG0673	inositol 2-dehydrogenase activity
EML492_19185	COG0395	ABC-type sugar transport system, permease component
EML492_19195	COG3842	ATPase activity
EML492_19220	COG1737	Transcriptional regulator
EML492_19250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EML492_19270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EML492_19280	COG0481	GTPase activity
EML492_19305	COG5006	permease, DMT superfamily
EML492_19330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EML492_19335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EML492_19340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EML492_19345	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EML492_19350	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EML492_19350	COG0072	phenylalanine-tRNA ligase activity
EML492_19360	COG4953	penicillin-binding protein 1C
EML492_19370	COG0667	Aldo Keto reductase
EML492_19375	COG0583	DNA-binding transcription factor activity
EML492_19390	COG0667	Aldo Keto reductase
EML492_19430	COG1570	exodeoxyribonuclease VII activity
EML492_19435	COG2249	NAD(P)H dehydrogenase (quinone) activity
EML492_19440	COG2309	aminopeptidase activity
EML492_19460	COG1393	Belongs to the ArsC family
EML492_19515	COG0583	DNA-binding transcription factor activity
EML492_19520	COG2249	NAD(P)H dehydrogenase (quinone) activity
EML492_19530	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_19540	COG3663	DNA glycosylase
EML492_19565	COG0583	DNA-binding transcription factor activity
EML492_19570	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_19580	COG0519	Catalyzes the synthesis of GMP from XMP
EML492_19580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EML492_19630	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EML492_19640	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EML492_19650	COG1968	undecaprenyl-diphosphatase activity
EML492_19670	COG0284	orotidine-5'-phosphate decarboxylase activity
EML492_19680	COG3963	phosphatidate phosphatase activity
EML492_19690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EML492_19695	COG0792	nuclease activity
EML492_19710	COG0189	ligase activity
EML492_19725	COG1280	lysine exporter protein (LysE YggA)
EML492_19730	COG1335	isochorismatase
EML492_19735	COG1280	lysine exporter protein (LysE YggA)
EML492_19755	COG1522	sequence-specific DNA binding
EML492_19765	COG0756	dUTP diphosphatase activity
EML492_19770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EML492_19795	COG0667	Aldo Keto reductase
EML492_19800	COG0583	DNA-binding transcription factor activity
EML492_19805	COG1720	tRNA m6t6A37 methyltransferase activity
EML492_19810	COG3585	molybdate ion transport
EML492_19815	COG3119	arylsulfatase activity
EML492_19820	COG0583	DNA-binding transcription factor activity
EML492_19825	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EML492_19830	COG1877	trehalose-phosphatase activity
EML492_19840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EML492_19850	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_19855	COG0583	DNA-binding transcription factor activity
EML492_19860	COG0583	DNA-binding transcription factor activity
EML492_19865	COG2814	Major facilitator Superfamily
EML492_19890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EML492_19910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EML492_19915	COG2986	histidine ammonia-lyase
EML492_19925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EML492_19930	COG2226	methyltransferase
EML492_19935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EML492_19940	COG1024	Enoyl-CoA hydratase
EML492_19945	COG0268	Binds directly to 16S ribosomal RNA
EML492_19950	COG1192	Involved in chromosome partitioning
EML492_19955	COG1475	DNA binding
EML492_19960	COG0640	Transcriptional regulator
EML492_19975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_19985	COG0583	DNA-binding transcription factor activity
EML492_20035	COG0745	RESPONSE REGULATOR receiver
EML492_20045	COG1012	belongs to the aldehyde dehydrogenase family
EML492_20050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_20065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_20115	COG1012	belongs to the aldehyde dehydrogenase family
EML492_20125	COG0840	transmembrane signaling receptor activity
EML492_20140	COG1902	pentaerythritol trinitrate reductase activity
EML492_20145	COG0427	acetyl-CoA hydrolase
EML492_20150	COG3547	Transposase (IS116 IS110 IS902 family)
EML492_20160	COG4208	sulfate ABC transporter
EML492_20165	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_20175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_20185	COG3842	ATPase activity
EML492_20190	COG0583	DNA-binding transcription factor activity
EML492_20195	COG1126	abc transporter atp-binding protein
EML492_20200	COG0765	amino acid transport
EML492_20205	COG0765	amino acid transport
EML492_20220	COG0667	Aldo Keto reductase
EML492_20225	COG0583	DNA-binding transcription factor activity
EML492_20230	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_20235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML492_20240	COG2267	carboxylic ester hydrolase activity
EML492_20245	COG0251	oxidation-reduction process
EML492_20250	COG1335	isochorismatase
EML492_20255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_20260	COG5265	(ABC) transporter
EML492_20275	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_20280	COG1846	Transcriptional regulator
EML492_20280	COG1940	carbohydrate kinase activity
EML492_20285	COG1082	Xylose isomerase domain protein TIM barrel
EML492_20290	COG2207	Transcriptional regulator
EML492_20290	COG1917	Cupin 2, conserved barrel domain protein
EML492_20300	COG1175	transmembrane transport
EML492_20315	COG1063	alcohol dehydrogenase
EML492_20320	COG3842	ATPase activity
EML492_20325	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_20345	COG0504	CTP synthase activity
EML492_20350	COG0006	proline dipeptidase activity
EML492_20355	COG4948	Mandelate Racemase Muconate Lactonizing
EML492_20360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_20365	COG1126	abc transporter atp-binding protein
EML492_20370	COG0765	amino acid transport
EML492_20375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_20380	COG2186	Transcriptional regulator
EML492_20385	COG1177	transmembrane transport
EML492_20395	COG3842	ATPase activity
EML492_20410	COG1024	Enoyl-CoA hydratase
EML492_20420	COG0277	FAD linked oxidase domain protein
EML492_20430	COG0604	alcohol dehydrogenase
EML492_20435	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EML492_20440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_20465	COG1802	Transcriptional regulator
EML492_20470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_20475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_20495	COG0765	amino acid transport
EML492_20500	COG0765	amino acid transport
EML492_20505	COG1126	abc transporter atp-binding protein
EML492_20520	COG0444	Belongs to the ABC transporter superfamily
EML492_20525	COG4608	Belongs to the ABC transporter superfamily
EML492_20530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_20540	COG0747	negative chemotaxis
EML492_20545	COG3257	ureidoglycine aminohydrolase activity
EML492_20550	COG0583	DNA-binding transcription factor activity
EML492_20555	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_20565	COG1335	isochorismatase
EML492_20570	COG0583	DNA-binding transcription factor activity
EML492_20575	COG0583	DNA-binding transcription factor activity
EML492_20595	COG0697	spore germination
EML492_20610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_20615	COG0683	leucine binding
EML492_20630	COG0411	ABC transporter
EML492_20645	COG1802	Transcriptional regulator
EML492_20660	COG1126	abc transporter atp-binding protein
EML492_20665	COG0765	amino acid transport
EML492_20670	COG0765	amino acid transport
EML492_20680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_20690	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_20695	COG2197	response regulator
EML492_20700	COG0601	transmembrane transport
EML492_20705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_20725	COG0747	negative chemotaxis
EML492_20750	COG4191	Histidine kinase
EML492_20750	COG0784	Response regulator, receiver
EML492_20755	COG2197	response regulator
EML492_20760	COG3237	CsbD-like
EML492_20770	COG3920	Histidine kinase
EML492_20780	COG0753	catalase activity
EML492_20795	COG0765	amino acid transport
EML492_20800	COG4597	amino acid ABC transporter
EML492_20805	COG4598	ABC transporter
EML492_20820	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML492_20825	COG4603	Belongs to the binding-protein-dependent transport system permease family
EML492_20830	COG3845	ABC transporter
EML492_20845	COG0793	Belongs to the peptidase S41A family
EML492_20850	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_20860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EML492_20870	COG4149	molybdate abc transporter
EML492_20875	COG3842	ATPase activity
EML492_20885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_20890	COG0583	DNA-binding transcription factor activity
EML492_20940	COG0583	DNA-binding transcription factor activity
EML492_20950	COG0583	DNA-binding transcription factor activity
EML492_20955	COG3384	dioxygenase
EML492_20975	COG0025	NhaP-type Na H and K H
EML492_20990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_20995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML492_21015	COG2022	thiamine diphosphate biosynthetic process
EML492_21030	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EML492_21035	COG1609	Transcriptional regulator
EML492_21045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_21050	COG0765	amino acid transport
EML492_21055	COG0765	amino acid transport
EML492_21065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML492_21075	COG0583	DNA-binding transcription factor activity
EML492_21090	COG0765	amino acid transport
EML492_21095	COG1126	abc transporter atp-binding protein
EML492_21100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_21105	COG1522	sequence-specific DNA binding
EML492_21120	COG0667	Aldo Keto reductase
EML492_21125	COG2814	Major facilitator Superfamily
EML492_21135	COG0583	DNA-binding transcription factor activity
EML492_21145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML492_21150	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EML492_21155	COG2080	2 iron, 2 sulfur cluster binding
EML492_21195	COG3153	acetyltransferase
EML492_21220	COG0698	ribose 5-phosphate isomerase
EML492_21225	COG0149	triose-phosphate isomerase activity
EML492_21260	COG1129	ABC transporter
EML492_21265	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_21270	COG1879	ABC-type sugar transport system periplasmic component
EML492_21275	COG1349	DNA-binding transcription factor activity
EML492_21280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML492_21285	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EML492_21295	COG0511	ligase activity, forming carbon-carbon bonds
EML492_21300	COG0439	Biotin carboxylase
EML492_21310	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_21315	COG1984	allophanate hydrolase subunit 2
EML492_21320	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_21325	COG0436	Aminotransferase
EML492_21335	COG4221	oxidoreductase activity
EML492_21340	COG0765	amino acid transport
EML492_21345	COG0765	amino acid transport
EML492_21360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EML492_21370	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_21400	COG3842	ATPase activity
EML492_21405	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_21420	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_21430	COG3842	ATPase activity
EML492_21435	COG0726	polysaccharide deacetylase
EML492_21445	COG0523	cobalamin synthesis protein
EML492_21460	COG2909	trisaccharide binding
EML492_21475	COG3842	ATPase activity
EML492_21485	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_21490	COG1177	transmembrane transport
EML492_21495	COG1129	ABC transporter
EML492_21500	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_21505	COG1879	ABC-type sugar transport system periplasmic component
EML492_21510	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_21515	COG2376	Dihydroxyacetone kinase
EML492_21525	COG2376	Dihydroxyacetone kinase
EML492_21550	COG2207	Transcriptional regulator
EML492_21555	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_21565	COG1335	isochorismatase
EML492_21575	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_21590	COG1012	belongs to the aldehyde dehydrogenase family
EML492_21595	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EML492_21600	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EML492_21620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EML492_21625	COG0784	Response regulator, receiver
EML492_21625	COG4191	Histidine kinase
EML492_21635	COG1294	oxidase, subunit
EML492_21640	COG1271	oxidase subunit
EML492_21645	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EML492_21650	COG4988	ABC transporter
EML492_21660	COG0517	IMP dehydrogenase activity
EML492_21660	COG0516	GMP reductase activity
EML492_21695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EML492_21700	COG3609	addiction module antidote protein, CC2985 family
EML492_21705	COG3668	Plasmid stabilization system
EML492_21745	COG2208	phosphoserine phosphatase activity
EML492_21750	COG2226	methyltransferase
EML492_21760	COG3300	MHYT domain
EML492_21760	COG5001	Diguanylate cyclase
EML492_21765	COG0745	RESPONSE REGULATOR receiver
EML492_21765	COG2205	protein histidine kinase activity
EML492_21765	COG3292	Two component regulator propeller
EML492_21775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EML492_21785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EML492_21825	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EML492_21825	COG2273	Hydrolase Family 16
EML492_21850	COG2197	response regulator
EML492_21855	COG2890	protein-(glutamine-N5) methyltransferase activity
EML492_21860	COG0367	asparagine synthase
EML492_21870	COG0318	PFAM AMP-dependent synthetase and ligase
EML492_21875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EML492_21880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EML492_21880	COG3321	synthase
EML492_21880	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EML492_21880	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EML492_21890	COG3300	MHYT domain
EML492_21890	COG5001	Diguanylate cyclase
EML492_21900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EML492_21930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_21935	COG1116	anion transmembrane transporter activity
EML492_21940	COG4191	Histidine kinase
EML492_21950	COG1609	Transcriptional regulator
EML492_21955	COG2271	Major facilitator Superfamily
EML492_21960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_21965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_22015	COG4774	siderophore transport
EML492_22020	COG2814	Major facilitator Superfamily
EML492_22035	COG1473	amidohydrolase
EML492_22050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_22060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_22105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_22120	COG0667	Aldo Keto reductase
EML492_22135	COG0747	negative chemotaxis
EML492_22140	COG0583	DNA-binding transcription factor activity
EML492_22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_22180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_22185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_22190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_22195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_22200	COG0454	-acetyltransferase
EML492_22205	COG0747	negative chemotaxis
EML492_22210	COG0747	negative chemotaxis
EML492_22230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_22285	COG1653	transport
EML492_22290	COG2188	Transcriptional regulator
EML492_22310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_22315	COG0601	transmembrane transport
EML492_22320	COG0747	negative chemotaxis
EML492_22325	COG2186	Transcriptional regulator
EML492_22330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_22335	COG0747	negative chemotaxis
EML492_22340	COG0601	transmembrane transport
EML492_22345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_22350	COG0444	Belongs to the ABC transporter superfamily
EML492_22355	COG4608	Belongs to the ABC transporter superfamily
EML492_22360	COG0483	inositol monophosphate 1-phosphatase activity
EML492_22365	COG0584	glycerophosphoryl diester phosphodiesterase
EML492_22370	COG1940	carbohydrate kinase activity
EML492_22375	COG5001	Diguanylate cyclase
EML492_22375	COG3300	MHYT domain
EML492_22395	COG3755	Protein conserved in bacteria
EML492_22415	COG0840	transmembrane signaling receptor activity
EML492_22420	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_22425	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_22430	COG1129	ABC transporter
EML492_22445	COG0477	Major facilitator Superfamily
EML492_22450	COG1309	transcriptional regulator
EML492_22455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EML492_22475	COG1396	sequence-specific DNA binding
EML492_22485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EML492_22500	COG0840	transmembrane signaling receptor activity
EML492_22515	COG3177	Filamentation induced by cAMP protein fic
EML492_22590	COG0583	DNA-binding transcription factor activity
EML492_22605	COG1309	transcriptional regulator
EML492_22610	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_22615	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EML492_22640	COG0668	transmembrane transport
EML492_22675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EML492_22705	COG0714	Associated with various cellular activities
EML492_22710	COG3119	arylsulfatase activity
EML492_22775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_22785	COG0583	DNA-binding transcription factor activity
EML492_22810	COG1162	GTPase activity
EML492_22825	COG1472	Belongs to the glycosyl hydrolase 3 family
EML492_22830	COG1846	Transcriptional regulator
EML492_22840	COG3842	ATPase activity
EML492_22845	COG1177	transmembrane transport
EML492_22850	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_22875	COG2207	Transcriptional regulator
EML492_22885	COG1752	Esterase of the alpha-beta hydrolase superfamily
EML492_22960	COG2375	cellular response to nickel ion
EML492_22960	COG1132	(ABC) transporter
EML492_22970	COG4774	siderophore transport
EML492_22975	COG1309	transcriptional regulator
EML492_22985	COG1982	Orn Lys Arg decarboxylase major
EML492_23000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EML492_23000	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EML492_23005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EML492_23010	COG1169	isochorismate synthase
EML492_23015	COG1021	2,3-dihydroxybenzoate-AMP ligase
EML492_23025	COG1169	isochorismate synthase
EML492_23075	COG1335	isochorismatase
EML492_23080	COG3845	ABC transporter
EML492_23095	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML492_23185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_23195	COG0747	negative chemotaxis
EML492_23200	COG1737	Transcriptional regulator
EML492_23210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_23220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_23225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EML492_23230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_23245	COG1024	Enoyl-CoA hydratase
EML492_23250	COG0583	DNA-binding transcription factor activity
EML492_23255	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EML492_23265	COG0583	DNA-binding transcription factor activity
EML492_23270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EML492_23275	COG3842	ATPase activity
EML492_23280	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_23285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EML492_23290	COG2072	flavoprotein involved in K transport
EML492_23310	COG0402	S-adenosylhomocysteine deaminase activity
EML492_23325	COG0583	DNA-binding transcription factor activity
EML492_23330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_23380	COG0444	Belongs to the ABC transporter superfamily
EML492_23385	COG2186	Transcriptional regulator
EML492_23390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_23395	COG0601	transmembrane transport
EML492_23410	COG1937	Protein conserved in bacteria
EML492_23455	COG2072	flavoprotein involved in K transport
EML492_23465	COG1845	cytochrome c oxidase, subunit III
EML492_23470	COG1845	cytochrome c oxidase, subunit III
EML492_23475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EML492_23480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EML492_23515	COG4221	oxidoreductase activity
EML492_23520	COG1309	transcriptional regulator
EML492_23530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EML492_23540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EML492_23560	COG1349	DNA-binding transcription factor activity
EML492_23575	COG2072	flavoprotein involved in K transport
EML492_23600	COG1335	isochorismatase
EML492_23615	COG0434	BtpA family
EML492_23620	COG1070	Carbohydrate kinase
EML492_23650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_23655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_23670	COG1733	regulation of RNA biosynthetic process
EML492_23700	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_23705	COG3321	synthase
EML492_23705	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_23705	COG0604	alcohol dehydrogenase
EML492_23720	COG1335	isochorismatase
EML492_23730	COG0583	DNA-binding transcription factor activity
EML492_23735	COG1741	Belongs to the pirin family
EML492_23755	COG1228	amidohydrolase
EML492_23770	COG2207	Transcriptional regulator
EML492_23790	COG2814	Major facilitator Superfamily
EML492_23805	COG2072	flavoprotein involved in K transport
EML492_23825	COG1472	Belongs to the glycosyl hydrolase 3 family
EML492_23840	COG0395	ABC-type sugar transport system, permease component
EML492_23845	COG1175	transmembrane transport
EML492_23850	COG1653	transport
EML492_23870	COG0601	transmembrane transport
EML492_23880	COG4608	Belongs to the ABC transporter superfamily
EML492_23890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_23955	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_23970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_23975	COG0159	tryptophan synthase activity
EML492_23985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_23990	COG3842	ATPase activity
EML492_23995	COG3833	ABC-type maltose transport systems, permease component
EML492_24000	COG1175	transmembrane transport
EML492_24015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_24025	COG1595	DNA-templated transcription, initiation
EML492_24060	COG0444	Belongs to the ABC transporter superfamily
EML492_24065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_24080	COG0747	negative chemotaxis
EML492_24085	COG2186	Transcriptional regulator
EML492_24110	COG3842	ATPase activity
EML492_24145	COG2272	Belongs to the type-B carboxylesterase lipase family
EML492_24160	COG2211	Major facilitator Superfamily
EML492_24180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EML492_24190	COG1280	lysine exporter protein (LysE YggA)
EML492_24195	COG2197	response regulator
EML492_24205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EML492_24210	COG0720	synthase
EML492_24215	COG0602	queuosine metabolic process
EML492_24230	COG2267	carboxylic ester hydrolase activity
EML492_24240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_24245	COG1012	belongs to the aldehyde dehydrogenase family
EML492_24265	COG1177	transmembrane transport
EML492_24270	COG3842	ATPase activity
EML492_24280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_24295	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_24305	COG0410	ABC transporter
EML492_24315	COG2706	6-phosphogluconolactonase activity
EML492_24320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_24325	COG1312	Catalyzes the dehydration of D-mannonate
EML492_24330	COG2186	Transcriptional regulator
EML492_24340	COG0601	transmembrane transport
EML492_24345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_24400	COG4774	siderophore transport
EML492_24415	COG1473	amidohydrolase
EML492_24420	COG0747	negative chemotaxis
EML492_24425	COG0601	transmembrane transport
EML492_24430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_24435	COG4172	Belongs to the ABC transporter superfamily
EML492_24445	COG3386	PFAM SMP-30 Gluconolaconase
EML492_24455	COG1063	alcohol dehydrogenase
EML492_24460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EML492_24465	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_24470	COG2084	Dehydrogenase
EML492_24480	COG1609	Transcriptional regulator
EML492_24490	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_24495	COG1129	ABC transporter
EML492_24505	COG0840	transmembrane signaling receptor activity
EML492_24525	COG4214	carbohydrate transport
EML492_24535	COG1070	Carbohydrate kinase
EML492_24540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_24545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_24550	COG0601	transmembrane transport
EML492_24575	COG4172	Belongs to the ABC transporter superfamily
EML492_24605	COG0673	inositol 2-dehydrogenase activity
EML492_24615	COG0395	ABC-type sugar transport system, permease component
EML492_24630	COG0673	inositol 2-dehydrogenase activity
EML492_24645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_24650	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
EML492_24655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EML492_24660	COG2390	Transcriptional regulator
EML492_24670	COG1940	carbohydrate kinase activity
EML492_24675	COG1879	ABC-type sugar transport system periplasmic component
EML492_24705	COG0765	amino acid transport
EML492_24710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_24720	COG1126	abc transporter atp-binding protein
EML492_24740	COG1522	sequence-specific DNA binding
EML492_24795	COG0864	Transcriptional regulator
EML492_24805	COG1609	Transcriptional regulator
EML492_24830	COG0697	spore germination
EML492_24835	COG0489	protein tyrosine kinase activity
EML492_24835	COG3206	protein involved in exopolysaccharide biosynthesis
EML492_24840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EML492_24845	COG1215	transferase activity, transferring glycosyl groups
EML492_24850	COG1215	transferase activity, transferring glycosyl groups
EML492_24855	COG1215	transferase activity, transferring glycosyl groups
EML492_24860	COG0438	transferase activity, transferring glycosyl groups
EML492_24865	COG2273	Hydrolase Family 16
EML492_24870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML492_24880	COG2244	polysaccharide biosynthetic process
EML492_24885	COG0463	Glycosyl transferase, family 2
EML492_24890	COG2327	Polysaccharide pyruvyl transferase
EML492_24895	COG1215	transferase activity, transferring glycosyl groups
EML492_24910	COG1596	polysaccharide export
EML492_24915	COG3307	-O-antigen
EML492_24920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML492_24930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_24950	COG2721	sulfolactate sulfo-lyase activity
EML492_24965	COG2207	Transcriptional regulator
EML492_24970	COG1486	melibiose metabolic process
EML492_24975	COG0747	negative chemotaxis
EML492_24980	COG0601	transmembrane transport
EML492_24985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_24990	COG4172	Belongs to the ABC transporter superfamily
EML492_24995	COG1486	melibiose metabolic process
EML492_25015	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EML492_25015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EML492_25020	COG1132	(ABC) transporter
EML492_25040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_25050	COG0747	negative chemotaxis
EML492_25080	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EML492_25095	COG1234	tRNA 3'-trailer cleavage
EML492_25120	COG0559	Belongs to the binding-protein-dependent transport system permease family
EML492_25130	COG0683	leucine binding
EML492_25140	COG3485	protocatechuate 3,4-dioxygenase
EML492_25145	COG3485	protocatechuate 3,4-dioxygenase
EML492_25150	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EML492_25155	COG2267	carboxylic ester hydrolase activity
EML492_25160	COG0583	DNA-binding transcription factor activity
EML492_25175	COG1414	Transcriptional regulator
EML492_25185	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EML492_25195	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_25230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EML492_25245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML492_25250	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EML492_25255	COG4208	sulfate ABC transporter
EML492_25265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EML492_25270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EML492_25280	COG2205	protein histidine kinase activity
EML492_25285	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EML492_25290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EML492_25295	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EML492_25330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_25335	COG0444	Belongs to the ABC transporter superfamily
EML492_25340	COG4608	Belongs to the ABC transporter superfamily
EML492_25355	COG2197	response regulator
EML492_25360	COG2205	protein histidine kinase activity
EML492_25360	COG0784	Response regulator, receiver
EML492_25375	COG0235	Class ii aldolase
EML492_25380	COG3395	kinase activity
EML492_25385	COG3622	Belongs to the hyi family
EML492_25390	COG2084	Dehydrogenase
EML492_25395	COG2271	Major facilitator Superfamily
EML492_25400	COG1609	Transcriptional regulator
EML492_25410	COG0765	amino acid transport
EML492_25415	COG0765	amino acid transport
EML492_25425	COG0251	oxidation-reduction process
EML492_25440	COG0235	Class ii aldolase
EML492_25450	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_25455	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_25460	COG1129	ABC transporter
EML492_25470	COG1609	Transcriptional regulator
EML492_25490	COG1215	transferase activity, transferring glycosyl groups
EML492_25530	COG1278	Cold shock
EML492_25545	COG0659	secondary active sulfate transmembrane transporter activity
EML492_25575	COG2205	protein histidine kinase activity
EML492_25580	COG1396	sequence-specific DNA binding
EML492_25615	COG1596	polysaccharide export
EML492_25620	COG0438	transferase activity, transferring glycosyl groups
EML492_25655	COG1215	transferase activity, transferring glycosyl groups
EML492_25695	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EML492_25720	COG0583	DNA-binding transcription factor activity
EML492_25725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_25730	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_25735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_25770	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_25780	COG1473	amidohydrolase
EML492_25795	COG0601	transmembrane transport
EML492_25810	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EML492_25825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML492_25835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_25840	COG0601	transmembrane transport
EML492_25845	COG0747	negative chemotaxis
EML492_25850	COG0306	phosphate transporter
EML492_25855	COG1392	Phosphate transport regulator
EML492_25860	COG3842	ATPase activity
EML492_25865	COG0395	ABC-type sugar transport system, permease component
EML492_25870	COG1175	transmembrane transport
EML492_25875	COG1653	transport
EML492_25880	COG0697	spore germination
EML492_25905	COG0747	negative chemotaxis
EML492_25915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_25925	COG1733	regulation of RNA biosynthetic process
EML492_25935	COG1132	(ABC) transporter
EML492_25940	COG0463	Glycosyl transferase, family 2
EML492_25945	COG1216	Glycosyl transferase, family 2
EML492_25950	COG2755	lipolytic protein G-D-S-L family
EML492_25950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EML492_25960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_25965	COG2079	MmgE PrpD family protein
EML492_25970	COG1126	abc transporter atp-binding protein
EML492_25975	COG0765	amino acid transport
EML492_26000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML492_26005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML492_26010	COG1120	ATPase activity
EML492_26020	COG5001	Diguanylate cyclase
EML492_26020	COG3300	MHYT domain
EML492_26040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_26045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML492_26055	COG0583	DNA-binding transcription factor activity
EML492_26070	COG0657	acetylesterase activity
EML492_26080	COG4166	transmembrane transport
EML492_26095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_26100	COG0601	transmembrane transport
EML492_26105	COG0747	negative chemotaxis
EML492_26120	COG1960	acyl-CoA dehydrogenase activity
EML492_26125	COG1250	3-hydroxyacyl-CoA dehydrogenase
EML492_26125	COG0824	Thioesterase
EML492_26130	COG3246	L-lysine catabolic process to acetate
EML492_26140	COG0583	DNA-binding transcription factor activity
EML492_26150	COG1609	Transcriptional regulator
EML492_26155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_26160	COG1126	abc transporter atp-binding protein
EML492_26165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_26185	COG3842	ATPase activity
EML492_26195	COG0395	ABC-type sugar transport system, permease component
EML492_26210	COG1461	Dihydroxyacetone kinase
EML492_26215	COG2376	Dihydroxyacetone kinase
EML492_26225	COG0673	inositol 2-dehydrogenase activity
EML492_26230	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_26235	COG1129	ABC transporter
EML492_26245	COG1879	ABC-type sugar transport system periplasmic component
EML492_26250	COG0287	Prephenate dehydrogenase
EML492_26260	COG1850	ribulose-bisphosphate carboxylase activity
EML492_26265	COG2186	Transcriptional regulator
EML492_26275	COG1968	undecaprenyl-diphosphatase activity
EML492_26280	COG2824	Alkylphosphonate utilization operon protein PhnA
EML492_26295	COG0352	thiamine-phosphate diphosphorylase activity
EML492_26300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EML492_26310	COG0625	glutathione transferase activity
EML492_26325	COG2204	response regulator
EML492_26330	COG4191	Histidine kinase
EML492_26335	COG1301	dicarboxylic acid transport
EML492_26340	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
EML492_26345	COG1136	(ABC) transporter
EML492_26345	COG0577	efflux transmembrane transporter activity
EML492_26355	COG1136	(ABC) transporter
EML492_26365	COG2169	Transcriptional regulator
EML492_26370	COG1414	Transcriptional regulator
EML492_26380	COG0747	negative chemotaxis
EML492_26400	COG4774	siderophore transport
EML492_26410	COG2819	hydrolase of the alpha beta superfamily
EML492_26415	COG1120	ATPase activity
EML492_26420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML492_26430	COG1522	sequence-specific DNA binding
EML492_26435	COG4172	Belongs to the ABC transporter superfamily
EML492_26440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_26445	COG0601	transmembrane transport
EML492_26475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_26480	COG0251	oxidation-reduction process
EML492_26500	COG1012	belongs to the aldehyde dehydrogenase family
EML492_26510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_26515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_26525	COG0454	-acetyltransferase
EML492_26540	COG1414	Transcriptional regulator
EML492_26555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EML492_26625	COG2207	Transcriptional regulator
EML492_26635	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EML492_26660	COG1136	(ABC) transporter
EML492_26660	COG0577	efflux transmembrane transporter activity
EML492_26665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_26680	COG0436	Aminotransferase
EML492_26690	COG0583	DNA-binding transcription factor activity
EML492_26705	COG0765	amino acid transport
EML492_26710	COG0765	amino acid transport
EML492_26715	COG1126	abc transporter atp-binding protein
EML492_26735	COG2197	response regulator
EML492_26740	COG4585	Histidine kinase
EML492_26750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_26760	COG0006	proline dipeptidase activity
EML492_26765	COG3842	ATPase activity
EML492_26770	COG0395	ABC-type sugar transport system, permease component
EML492_26785	COG0626	cystathionine gamma-synthase activity
EML492_26790	COG2186	Transcriptional regulator
EML492_26800	COG0657	acetylesterase activity
EML492_26800	COG2755	lipolytic protein G-D-S-L family
EML492_26820	COG3842	ATPase activity
EML492_26830	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_26835	COG0395	ABC-type sugar transport system, permease component
EML492_26855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_26860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_26865	COG1473	amidohydrolase
EML492_26875	COG1126	abc transporter atp-binding protein
EML492_26880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_26890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_26895	COG1215	transferase activity, transferring glycosyl groups
EML492_26905	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_26910	COG1129	ABC transporter
EML492_26915	COG4213	ABC transporter substrate-binding protein
EML492_26930	COG4993	Dehydrogenase
EML492_26950	COG1940	carbohydrate kinase activity
EML492_26950	COG1846	Transcriptional regulator
EML492_26965	COG0395	ABC-type sugar transport system, permease component
EML492_27020	COG0277	FAD linked oxidase domain protein
EML492_27060	COG1902	pentaerythritol trinitrate reductase activity
EML492_27105	COG0667	Aldo Keto reductase
EML492_27120	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML492_27120	COG1902	pentaerythritol trinitrate reductase activity
EML492_27130	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EML492_27140	COG4176	ABC-type proline glycine betaine transport system permease component
EML492_27145	COG4175	Glycine betaine
EML492_27145	COG0517	IMP dehydrogenase activity
EML492_27150	COG1278	Cold shock
EML492_27155	COG5342	invasion associated locus B
EML492_27195	COG1349	DNA-binding transcription factor activity
EML492_27205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_27220	COG1175	transmembrane transport
EML492_27225	COG0395	ABC-type sugar transport system, permease component
EML492_27230	COG2204	response regulator
EML492_27235	COG4191	Histidine kinase
EML492_27250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EML492_27260	COG1609	Transcriptional regulator
EML492_27270	COG1175	transmembrane transport
EML492_27275	COG0395	ABC-type sugar transport system, permease component
EML492_27295	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EML492_27300	COG0625	glutathione transferase activity
EML492_27320	COG3845	ABC transporter
EML492_27330	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML492_27345	COG0243	molybdopterin cofactor binding
EML492_27355	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EML492_27360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EML492_27370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_27375	COG0601	transmembrane transport
EML492_27380	COG0747	negative chemotaxis
EML492_27385	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EML492_27390	COG2971	BadF BadG BcrA BcrD
EML492_27395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EML492_27400	COG1737	Transcriptional regulator
EML492_27405	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_27415	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EML492_27420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EML492_27445	COG1116	anion transmembrane transporter activity
EML492_27450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_27460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EML492_27465	COG0747	negative chemotaxis
EML492_27470	COG4608	Belongs to the ABC transporter superfamily
EML492_27490	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_27495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_27500	COG0601	transmembrane transport
EML492_27515	COG0584	glycerophosphoryl diester phosphodiesterase
EML492_27520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_27530	COG4172	Belongs to the ABC transporter superfamily
EML492_27545	COG1609	Transcriptional regulator
EML492_27560	COG2137	regulation of response to DNA damage stimulus
EML492_27565	COG1802	Transcriptional regulator
EML492_27570	COG1126	abc transporter atp-binding protein
EML492_27575	COG0765	amino acid transport
EML492_27580	COG0765	amino acid transport
EML492_27590	COG1063	alcohol dehydrogenase
EML492_27595	COG0246	Mannitol dehydrogenase
EML492_27600	COG1312	Catalyzes the dehydration of D-mannonate
EML492_27605	COG1802	Transcriptional regulator
EML492_27610	COG0667	Aldo Keto reductase
EML492_27620	COG1473	amidohydrolase
EML492_27645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EML492_27650	COG0667	Aldo Keto reductase
EML492_27655	COG0583	DNA-binding transcription factor activity
EML492_27660	COG0450	alkyl hydroperoxide reductase
EML492_27680	COG2273	Hydrolase Family 16
EML492_27680	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EML492_27685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_27690	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EML492_27695	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EML492_27700	COG2894	cell division
EML492_27705	COG0850	regulation of cytokinetic process
EML492_27710	COG0668	transmembrane transport
EML492_27720	COG0252	asparaginase activity
EML492_27730	COG1027	Aspartate ammonia-lyase
EML492_27735	COG2186	Transcriptional regulator
EML492_27765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_27770	COG4172	Belongs to the ABC transporter superfamily
EML492_27775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_27790	COG1802	Transcriptional regulator
EML492_27795	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EML492_27800	COG1522	sequence-specific DNA binding
EML492_27810	COG0318	PFAM AMP-dependent synthetase and ligase
EML492_27820	COG1802	Transcriptional regulator
EML492_27825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_27830	COG1473	amidohydrolase
EML492_27835	COG1126	abc transporter atp-binding protein
EML492_27840	COG0765	amino acid transport
EML492_27860	COG2226	methyltransferase
EML492_27865	COG1120	ATPase activity
EML492_27870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML492_27880	COG1082	Xylose isomerase domain protein TIM barrel
EML492_27880	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EML492_27885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EML492_27925	COG5383	Protein conserved in bacteria
EML492_27930	COG0583	DNA-binding transcription factor activity
EML492_27935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EML492_27940	COG1454	alcohol dehydrogenase
EML492_27950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_27955	COG0747	negative chemotaxis
EML492_27960	COG0601	transmembrane transport
EML492_27965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_27970	COG0444	Belongs to the ABC transporter superfamily
EML492_27975	COG4608	Belongs to the ABC transporter superfamily
EML492_27995	COG0330	HflC and HflK could
EML492_28005	COG2217	Heavy metal translocating P-type atpase
EML492_28030	COG4789	Type iii secretion
EML492_28040	COG4792	protein secretion
EML492_28050	COG1987	bacterial-type flagellum assembly
EML492_28055	COG4790	Type iii secretion
EML492_28060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EML492_28080	COG4669	(LipO)protein
EML492_28100	COG2207	Transcriptional regulator
EML492_28125	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EML492_28130	COG0459	protein refolding
EML492_28145	COG1301	dicarboxylic acid transport
EML492_28150	COG0583	DNA-binding transcription factor activity
EML492_28170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EML492_28180	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EML492_28185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EML492_28190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EML492_28195	COG1120	ATPase activity
EML492_28210	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EML492_28220	COG0535	radical SAM domain protein
EML492_28225	COG0535	radical SAM domain protein
EML492_28230	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
EML492_28235	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EML492_28255	COG1064	alcohol dehydrogenase
EML492_28275	COG3707	response regulator
EML492_28280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_28285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_28290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_28295	COG1116	anion transmembrane transporter activity
EML492_28300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EML492_28310	COG0243	molybdopterin cofactor binding
EML492_28335	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EML492_28345	COG4977	sequence-specific DNA binding
EML492_28370	COG2011	ABC-type metal ion transport system permease component
EML492_28375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EML492_28380	COG1464	Belongs to the NlpA lipoprotein family
EML492_28395	COG4651	solute:proton antiporter activity
EML492_28395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EML492_28400	COG1063	alcohol dehydrogenase
EML492_28410	COG0477	Major facilitator Superfamily
EML492_28415	COG2186	Transcriptional regulator
EML492_28420	COG2814	Major facilitator Superfamily
EML492_28440	COG1940	carbohydrate kinase activity
EML492_28450	COG2186	Transcriptional regulator
EML492_28465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_28470	COG0405	Gamma-glutamyltransferase
EML492_28485	COG0386	Belongs to the glutathione peroxidase family
EML492_28490	COG4106	trans-aconitate 2-methyltransferase activity
EML492_28500	COG1940	carbohydrate kinase activity
EML492_28515	COG4952	isomerase
EML492_28520	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_28520	COG3347	Dehydrogenase
EML492_28525	COG1349	DNA-binding transcription factor activity
EML492_28545	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_28560	COG0583	DNA-binding transcription factor activity
EML492_28565	COG0625	glutathione transferase activity
EML492_28590	COG0673	inositol 2-dehydrogenase activity
EML492_28595	COG1309	transcriptional regulator
EML492_28605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML492_28615	COG1070	Carbohydrate kinase
EML492_28625	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EML492_28630	COG0667	Aldo Keto reductase
EML492_28640	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_28645	COG1129	ABC transporter
EML492_28660	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EML492_28675	COG1802	Transcriptional regulator
EML492_28680	COG1914	H( )-stimulated, divalent metal cation uptake system
EML492_28685	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_28690	COG4336	lyase activity
EML492_28695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_28700	COG4770	biotin carboxylase activity
EML492_28720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EML492_28735	COG3547	Transposase (IS116 IS110 IS902 family)
EML492_28755	COG1802	Transcriptional regulator
EML492_28765	COG0601	transmembrane transport
EML492_28770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_28780	COG4608	Belongs to the ABC transporter superfamily
EML492_28790	COG0154	amidase activity
EML492_28810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_28820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_28825	COG2828	Protein conserved in bacteria
EML492_28830	COG0583	DNA-binding transcription factor activity
EML492_28850	COG0745	RESPONSE REGULATOR receiver
EML492_28855	COG5002	protein histidine kinase activity
EML492_28855	COG3850	Histidine kinase
EML492_28885	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EML492_28890	COG0583	DNA-binding transcription factor activity
EML492_28895	COG0655	NAD(P)H dehydrogenase (quinone) activity
EML492_28905	COG1064	alcohol dehydrogenase
EML492_28940	COG2814	Major facilitator Superfamily
EML492_28950	COG2353	YceI-like domain
EML492_28985	COG2514	catechol 2,3-dioxygenase activity
EML492_28995	COG0583	DNA-binding transcription factor activity
EML492_29005	COG1175	transmembrane transport
EML492_29010	COG0395	ABC-type sugar transport system, permease component
EML492_29025	COG1917	Cupin 2, conserved barrel domain protein
EML492_29025	COG2207	Transcriptional regulator
EML492_29030	COG0840	transmembrane signaling receptor activity
EML492_29040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EML492_29065	COG2086	electron transfer activity
EML492_29075	COG1802	Transcriptional regulator
EML492_29080	COG5006	permease, DMT superfamily
EML492_29085	COG1126	abc transporter atp-binding protein
EML492_29090	COG0765	amino acid transport
EML492_29095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_29110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_29110	COG2022	thiamine diphosphate biosynthetic process
EML492_29120	COG0583	DNA-binding transcription factor activity
EML492_29125	COG1942	4-Oxalocrotonate Tautomerase
EML492_29145	COG0579	oxidoreductase
EML492_29150	COG1802	Transcriptional regulator
EML492_29160	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_29170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EML492_29175	COG0179	Fumarylacetoacetate (FAA) hydrolase
EML492_29180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EML492_29185	COG2814	Major facilitator Superfamily
EML492_29190	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_29210	COG3485	protocatechuate 3,4-dioxygenase
EML492_29235	COG3547	Transposase (IS116 IS110 IS902 family)
EML492_29245	COG1802	Transcriptional regulator
EML492_29255	COG1122	ATPase activity
EML492_29260	COG4120	Belongs to the binding-protein-dependent transport system permease family
EML492_29285	COG5001	Diguanylate cyclase
EML492_29295	COG1312	Catalyzes the dehydration of D-mannonate
EML492_29305	COG3250	beta-galactosidase activity
EML492_29310	COG3459	Glycosyltransferase 36 associated
EML492_29315	COG0656	L-ascorbic acid biosynthetic process
EML492_29320	COG2814	Major facilitator Superfamily
EML492_29325	COG0583	DNA-binding transcription factor activity
EML492_29350	COG1132	(ABC) transporter
EML492_29355	COG1032	radical SAM domain protein
EML492_29375	COG2223	nitrite transmembrane transporter activity
EML492_29385	COG2169	Transcriptional regulator
EML492_29415	COG3634	alkyl hydroperoxide reductase activity
EML492_29420	COG0583	DNA-binding transcription factor activity
EML492_29435	COG2197	response regulator
EML492_29440	COG2267	carboxylic ester hydrolase activity
EML492_29450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_29465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EML492_29465	COG3743	rRNA binding
EML492_29485	COG2224	Isocitrate lyase
EML492_29500	COG4585	Histidine kinase
EML492_29505	COG1879	ABC-type sugar transport system periplasmic component
EML492_29510	COG1129	ABC transporter
EML492_29515	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_29525	COG3386	PFAM SMP-30 Gluconolaconase
EML492_29530	COG1802	Transcriptional regulator
EML492_29545	COG0765	amino acid transport
EML492_29550	COG1126	abc transporter atp-binding protein
EML492_29560	COG1063	alcohol dehydrogenase
EML492_29565	COG2721	sulfolactate sulfo-lyase activity
EML492_29570	COG1396	sequence-specific DNA binding
EML492_29580	COG1024	Enoyl-CoA hydratase
EML492_29585	COG1250	3-hydroxyacyl-CoA dehydrogenase
EML492_29595	COG2986	histidine ammonia-lyase
EML492_29630	COG2030	dehydratase
EML492_29645	COG1732	Glycine betaine
EML492_29665	COG1174	glycine betaine transport
EML492_29700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_29705	COG0840	transmembrane signaling receptor activity
EML492_29730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_29735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EML492_29750	COG0069	glutamate synthase activity
EML492_29755	COG2218	PFAM glutamate synthase alpha subunit domain protein
EML492_29760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EML492_29770	COG4977	sequence-specific DNA binding
EML492_29775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_29780	COG4311	Sarcosine oxidase, delta subunit
EML492_29785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EML492_29785	COG0446	pyridine nucleotide-disulphide oxidoreductase
EML492_29800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EML492_29805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EML492_29810	COG1121	(ABC) transporter
EML492_29815	COG0803	Belongs to the bacterial solute-binding protein 9 family
EML492_29840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EML492_29845	COG1522	sequence-specific DNA binding
EML492_29850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EML492_29855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_29875	COG1082	Xylose isomerase domain protein TIM barrel
EML492_29885	COG1175	transmembrane transport
EML492_29890	COG0395	ABC-type sugar transport system, permease component
EML492_29895	COG3842	ATPase activity
EML492_29935	COG0395	ABC-type sugar transport system, permease component
EML492_29940	COG1175	transmembrane transport
EML492_29955	COG1309	transcriptional regulator
EML492_29960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EML492_29980	COG1012	belongs to the aldehyde dehydrogenase family
EML492_30005	COG0411	ABC transporter
EML492_30035	COG2080	2 iron, 2 sulfur cluster binding
EML492_30040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML492_30040	COG2010	Cytochrome c
EML492_30050	COG1846	Transcriptional regulator
EML492_30090	COG1846	Transcriptional regulator
EML492_30105	COG0411	ABC transporter
EML492_30115	COG2188	Transcriptional regulator
EML492_30120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_30130	COG0601	transmembrane transport
EML492_30135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_30165	COG1116	anion transmembrane transporter activity
EML492_30170	COG4191	Histidine kinase
EML492_30175	COG4566	intracellular signal transduction
EML492_30185	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EML492_30190	COG1780	Probably involved in ribonucleotide reductase function
EML492_30200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EML492_30205	COG0671	phosphoesterase, PA-phosphatase related
EML492_30210	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_30215	COG1177	transmembrane transport
EML492_30225	COG1396	sequence-specific DNA binding
EML492_30230	COG3842	ATPase activity
EML492_30260	COG0626	cystathionine gamma-synthase activity
EML492_30275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EML492_30295	COG1120	ATPase activity
EML492_30320	COG4774	siderophore transport
EML492_30325	COG2819	hydrolase of the alpha beta superfamily
EML492_30330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EML492_30340	COG0625	glutathione transferase activity
EML492_30350	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EML492_30365	COG1522	sequence-specific DNA binding
EML492_30380	COG0840	transmembrane signaling receptor activity
EML492_30395	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EML492_30400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EML492_30405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EML492_30405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EML492_30415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EML492_30425	COG1609	Transcriptional regulator
EML492_30430	COG1063	alcohol dehydrogenase
EML492_30450	COG0673	inositol 2-dehydrogenase activity
EML492_30460	COG2390	Transcriptional regulator
EML492_30465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML492_30470	COG3958	Transketolase
EML492_30475	COG3959	Transketolase, thiamine diphosphate binding domain
EML492_30480	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_30490	COG1129	ABC transporter
EML492_30495	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_30500	COG0149	triose-phosphate isomerase activity
EML492_30505	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_30510	COG1082	Xylose isomerase domain protein TIM barrel
EML492_30515	COG0673	inositol 2-dehydrogenase activity
EML492_30520	COG1082	Xylose isomerase domain protein TIM barrel
EML492_30545	COG2130	NADP-dependent
EML492_30595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EML492_30605	COG3938	Belongs to the proline racemase family
EML492_30610	COG4176	ABC-type proline glycine betaine transport system permease component
EML492_30615	COG4176	ABC-type proline glycine betaine transport system permease component
EML492_30620	COG4175	Glycine betaine
EML492_30620	COG3448	diguanylate cyclase activity
EML492_30635	COG1012	belongs to the aldehyde dehydrogenase family
EML492_30640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EML492_30645	COG1802	Transcriptional regulator
EML492_30665	COG0840	transmembrane signaling receptor activity
EML492_30670	COG0395	ABC-type sugar transport system, permease component
EML492_30675	COG1175	transmembrane transport
EML492_30680	COG1653	transport
EML492_30685	COG3842	ATPase activity
EML492_30690	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_30695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EML492_30700	COG2186	Transcriptional regulator
EML492_30730	COG1116	anion transmembrane transporter activity
EML492_30735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_30750	COG0640	Transcriptional regulator
EML492_30795	COG0436	Aminotransferase
EML492_30810	COG1079	Belongs to the binding-protein-dependent transport system permease family
EML492_30855	COG0659	secondary active sulfate transmembrane transporter activity
EML492_30865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EML492_30870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EML492_30895	COG0438	transferase activity, transferring glycosyl groups
EML492_30900	COG2144	transferase activity, transferring acyl groups
EML492_30925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EML492_30935	COG0300	oxidoreductase activity
EML492_30960	COG1175	transmembrane transport
EML492_30965	COG0395	ABC-type sugar transport system, permease component
EML492_30970	COG3842	ATPase activity
EML492_30990	COG4774	siderophore transport
EML492_31010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EML492_31015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EML492_31020	COG2186	Transcriptional regulator
EML492_31025	COG0747	negative chemotaxis
EML492_31030	COG0601	transmembrane transport
EML492_31035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_31045	COG0402	S-adenosylhomocysteine deaminase activity
EML492_31055	COG4608	Belongs to the ABC transporter superfamily
EML492_31065	COG0583	DNA-binding transcription factor activity
EML492_31070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EML492_31080	COG1129	ABC transporter
EML492_31090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EML492_31100	COG0747	negative chemotaxis
EML492_31105	COG0601	transmembrane transport
EML492_31110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_31115	COG4172	Belongs to the ABC transporter superfamily
EML492_31125	COG3932	Exopolysaccharide synthesis, ExoD
EML492_31145	COG0765	amino acid transport
EML492_31165	COG0006	proline dipeptidase activity
EML492_31185	COG1802	Transcriptional regulator
EML492_31190	COG1984	allophanate hydrolase subunit 2
EML492_31195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_31200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EML492_31215	COG0765	amino acid transport
EML492_31220	COG0765	amino acid transport
EML492_31230	COG0010	Belongs to the arginase family
EML492_31250	COG2072	flavoprotein involved in K transport
EML492_31255	COG1126	abc transporter atp-binding protein
EML492_31260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EML492_31265	COG0765	amino acid transport
EML492_31270	COG0765	amino acid transport
EML492_31280	COG1921	L-seryl-tRNASec selenium transferase activity
EML492_31295	COG3964	amidohydrolase
EML492_31305	COG0601	transmembrane transport
EML492_31310	COG0747	negative chemotaxis
EML492_31335	COG0028	Belongs to the TPP enzyme family
EML492_31340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EML492_31355	COG2837	iron assimilation
EML492_31370	COG0542	response to heat
EML492_31375	COG4191	Histidine kinase
EML492_31390	COG0484	heat shock protein binding
EML492_31400	COG0303	'Molybdopterin
EML492_31405	COG0668	transmembrane transport
EML492_31410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EML492_31430	COG1294	oxidase, subunit
EML492_31435	COG1271	oxidase subunit
EML492_31440	COG0243	molybdopterin cofactor binding
EML492_31445	COG3781	membrane
EML492_31480	COG0300	oxidoreductase activity
EML492_31505	COG0667	Aldo Keto reductase
EML492_31515	COG1902	pentaerythritol trinitrate reductase activity
EML492_31525	COG1609	Transcriptional regulator
EML492_31530	COG1840	ABC-type Fe3 transport system, periplasmic component
EML492_31540	COG3842	ATPase activity
EML492_31570	COG1215	transferase activity, transferring glycosyl groups
EML492_31580	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
EML492_31590	COG4251	negative regulation of phosphorylation
EML492_31590	COG3706	GGDEF domain
EML492_31590	COG5001	Diguanylate cyclase
EML492_31590	COG2203	Gaf domain
EML492_31595	COG1609	Transcriptional regulator
EML492_31605	COG1129	ABC transporter
EML492_31610	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_31665	COG1459	type II secretion system
EML492_31670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EML492_31695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EML492_31725	COG1376	ErfK ybiS ycfS ynhG family protein
EML492_31740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_31745	COG1473	amidohydrolase
EML492_31770	COG0436	Aminotransferase
EML492_31780	COG4302	ethanolamine ammonia-lyase activity
EML492_31785	COG4303	Ethanolamine ammonia lyase large subunit
EML492_31805	COG0235	Class ii aldolase
EML492_31815	COG3239	Fatty acid desaturase
EML492_31830	COG1116	anion transmembrane transporter activity
EML492_31840	COG3665	Urea carboxylase-associated protein
EML492_31845	COG4770	biotin carboxylase activity
EML492_31855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EML492_31885	COG0596	Alpha beta hydrolase
EML492_31890	COG1192	Involved in chromosome partitioning
EML492_31895	COG1475	DNA binding
EML492_31900	COG0640	Transcriptional regulator
EML492_32000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EML492_32065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_32070	COG4172	Belongs to the ABC transporter superfamily
EML492_32075	COG0747	negative chemotaxis
EML492_32090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EML492_32105	COG0601	transmembrane transport
EML492_32110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_32125	COG0667	Aldo Keto reductase
EML492_32130	COG0129	dihydroxy-acid dehydratase activity
EML492_32135	COG0300	oxidoreductase activity
EML492_32150	COG3842	ATPase activity
EML492_32155	COG1176	ABC-type spermidine putrescine transport system, permease component I
EML492_32165	COG2222	sugar isomerase
EML492_32170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EML492_32190	COG3300	MHYT domain
EML492_32190	COG5001	Diguanylate cyclase
EML492_32205	COG1283	sodium-dependent phosphate transmembrane transporter activity
EML492_32220	COG0444	Belongs to the ABC transporter superfamily
EML492_32225	COG4608	Belongs to the ABC transporter superfamily
EML492_32240	COG0584	glycerophosphoryl diester phosphodiesterase
EML492_32245	COG0483	inositol monophosphate 1-phosphatase activity
EML492_32260	COG4302	ethanolamine ammonia-lyase activity
EML492_32265	COG4303	Ethanolamine ammonia lyase large subunit
EML492_32275	COG0154	amidase activity
EML492_32290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_32295	COG4172	Belongs to the ABC transporter superfamily
EML492_32300	COG1349	DNA-binding transcription factor activity
EML492_32305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_32325	COG1940	carbohydrate kinase activity
EML492_32335	COG1879	ABC-type sugar transport system periplasmic component
EML492_32345	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_32360	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML492_32370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML492_32375	COG0563	adenylate kinase activity
EML492_32380	COG2972	Histidine kinase
EML492_32380	COG0840	transmembrane signaling receptor activity
EML492_32390	COG0191	fructose-bisphosphate aldolase activity
EML492_32395	COG0149	triose-phosphate isomerase activity
EML492_32440	COG1475	DNA binding
EML492_32480	COG4227	nucleotidyltransferase activity
EML492_32490	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EML492_32495	COG5489	Protein of unknown function (DUF736)
EML492_32500	COG2161	toxin-antitoxin pair type II binding
EML492_32515	COG5489	Protein of unknown function (DUF736)
EML492_32525	COG3831	ATPase activity
EML492_32535	COG1879	ABC-type sugar transport system periplasmic component
EML492_32540	COG0840	transmembrane signaling receptor activity
EML492_32550	COG3505	Type IV secretory pathway VirD4
EML492_32565	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EML492_32570	COG4959	Type IV secretory pathway protease TraF
EML492_32575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EML492_32595	COG1476	TRANSCRIPTIONal
EML492_32605	COG2771	luxR family
EML492_32610	COG2948	multi-organism process
EML492_32620	COG3504	Conjugal transfer protein
EML492_32625	COG3701	Conjugal transfer protein
EML492_32630	COG3846	protein secretion by the type IV secretion system
EML492_32640	COG5314	conjugation
EML492_32650	COG5268	conjugation
EML492_32655	COG3838	Conjugal transfer protein Trbc
EML492_32660	COG4962	Type ii secretion system protein e
EML492_32665	COG3916	Acyl-homoserine-lactone synthase
EML492_32670	COG1192	Involved in chromosome partitioning
EML492_32675	COG1475	DNA binding
EML492_32680	COG0640	Transcriptional regulator
EML492_32685	COG2963	transposase activity
EML492_32720	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EML492_32830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EML492_32840	COG3436	PFAM IS66 Orf2 family protein
EML492_32845	COG2963	transposase activity
EML492_32850	COG3161	chorismate lyase activity
EML492_32855	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EML492_32930	COG0745	RESPONSE REGULATOR receiver
EML492_32940	COG1192	Involved in chromosome partitioning
EML492_32950	COG3843	relaxase mobilization nuclease domain protein
EML492_32955	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
EML492_32960	COG3505	Type IV secretory pathway VirD4
EML492_32995	COG0747	negative chemotaxis
EML492_33015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_33020	COG0584	glycerophosphoryl diester phosphodiesterase
EML492_33155	COG0583	DNA-binding transcription factor activity
EML492_33160	COG5383	Protein conserved in bacteria
EML492_33165	COG1012	belongs to the aldehyde dehydrogenase family
EML492_33170	COG0436	Aminotransferase
EML492_33175	COG0247	lactate metabolic process
EML492_33175	COG0277	FAD linked oxidase domain protein
EML492_33185	COG1522	sequence-specific DNA binding
EML492_33190	COG0154	amidase activity
EML492_33195	COG1231	oxidoreductase activity
EML492_33205	COG2222	sugar isomerase
EML492_33210	COG1028	Short-chain dehydrogenase reductase Sdr
EML492_33215	COG0006	proline dipeptidase activity
EML492_33225	COG0667	Aldo Keto reductase
EML492_33235	COG0300	oxidoreductase activity
EML492_33255	COG0006	proline dipeptidase activity
EML492_33260	COG3842	ATPase activity
EML492_33280	COG0840	transmembrane signaling receptor activity
EML492_33280	COG2972	Histidine kinase
EML492_33300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EML492_33305	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EML492_33310	COG2080	2 iron, 2 sulfur cluster binding
EML492_33315	COG2814	Major facilitator Superfamily
EML492_33355	COG1064	alcohol dehydrogenase
EML492_33365	COG0655	NAD(P)H dehydrogenase (quinone) activity
EML492_33370	COG0583	DNA-binding transcription factor activity
EML492_33375	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EML492_33410	COG4302	ethanolamine ammonia-lyase activity
EML492_33415	COG4303	Ethanolamine ammonia lyase large subunit
EML492_33425	COG0154	amidase activity
EML492_33440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EML492_33445	COG4172	Belongs to the ABC transporter superfamily
EML492_33450	COG1349	DNA-binding transcription factor activity
EML492_33455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EML492_33475	COG1940	carbohydrate kinase activity
EML492_33485	COG1879	ABC-type sugar transport system periplasmic component
EML492_33495	COG1172	Belongs to the binding-protein-dependent transport system permease family
EML492_33510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EML492_33520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EML492_33525	COG0563	adenylate kinase activity
EML492_33530	COG2972	Histidine kinase
EML492_33530	COG0840	transmembrane signaling receptor activity
EML492_33540	COG0191	fructose-bisphosphate aldolase activity
EML492_33545	COG0149	triose-phosphate isomerase activity
EML492_33585	COG1475	DNA binding
EML492_33620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EML492_33625	COG5489	Protein of unknown function (DUF736)
EML492_33635	COG5489	Protein of unknown function (DUF736)
EML492_33650	COG3831	ATPase activity
EML492_33660	COG1879	ABC-type sugar transport system periplasmic component
EML492_33665	COG0840	transmembrane signaling receptor activity
EML492_33680	COG3505	Type IV secretory pathway VirD4
EML492_33695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EML492_33700	COG4959	Type IV secretory pathway protease TraF
EML492_33705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EML492_33715	COG3177	Filamentation induced by cAMP protein fic
EML492_33730	COG2771	luxR family
EML492_33735	COG2948	multi-organism process
EML492_33745	COG3504	Conjugal transfer protein
EML492_33750	COG3701	Conjugal transfer protein
EML492_33755	COG3846	protein secretion by the type IV secretion system
EML492_33765	COG5314	conjugation
EML492_33770	COG3451	type IV secretory pathway VirB4
EML492_33775	COG5268	conjugation
EML492_33780	COG3838	Conjugal transfer protein Trbc
EML492_33785	COG4962	Type ii secretion system protein e
EML492_33790	COG3916	Acyl-homoserine-lactone synthase