locus-tag	class	description
G6M87_00045	COG3038	cytochrome b561
G6M87_00060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G6M87_00070	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
G6M87_00075	COG2948	multi-organism process
G6M87_00080	COG3504	Conjugal transfer protein
G6M87_00085	COG3736	Type IV secretory pathway, component VirB8
G6M87_00095	COG3704	protein secretion by the type IV secretion system
G6M87_00110	COG3451	type IV secretory pathway VirB4
G6M87_00115	COG3702	type iv secretory pathway
G6M87_00120	COG3838	Conjugal transfer protein Trbc
G6M87_00165	COG1396	sequence-specific DNA binding
G6M87_00170	COG1476	TRANSCRIPTIONal
G6M87_00175	COG1396	sequence-specific DNA binding
G6M87_00215	COG3505	Type IV secretory pathway VirD4
G6M87_00235	COG3754	Rhamnan synthesis protein F
G6M87_00240	COG0463	Glycosyl transferase, family 2
G6M87_00240	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
G6M87_00275	COG1088	dTDP-glucose 4,6-dehydratase activity
G6M87_00280	COG1091	dTDP-4-dehydrorhamnose reductase activity
G6M87_00315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G6M87_00320	COG0438	transferase activity, transferring glycosyl groups
G6M87_00350	COG3220	belongs to the UPF0276 family
G6M87_00390	COG4650	regulator
G6M87_00405	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G6M87_00430	COG1715	Restriction endonuclease
G6M87_00440	COG3436	PFAM IS66 Orf2 family protein
G6M87_00445	COG4372	Transposase
G6M87_00455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6M87_00500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6M87_00505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G6M87_00520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G6M87_00525	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G6M87_00530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G6M87_00535	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G6M87_00545	COG0725	ABC transporter, periplasmic molybdate-binding protein
G6M87_00550	COG4149	molybdate abc transporter
G6M87_00555	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G6M87_00560	COG3585	molybdate ion transport
G6M87_00560	COG2005	Transcriptional regulator
G6M87_00565	COG0799	negative regulation of ribosome biogenesis
G6M87_00570	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G6M87_00580	COG0793	Belongs to the peptidase S41A family
G6M87_00590	COG0494	nUDIX hydrolase
G6M87_00605	COG0587	DNA-directed DNA polymerase activity
G6M87_00630	COG2301	Belongs to the HpcH HpaI aldolase family
G6M87_00640	COG0066	3-isopropylmalate dehydratase activity
G6M87_00650	COG0473	3-isopropylmalate dehydrogenase activity
G6M87_00655	COG0671	phosphoesterase, PA-phosphatase related
G6M87_00665	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_00670	COG0783	Belongs to the Dps family
G6M87_00675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G6M87_00685	COG0288	reversible hydration of carbon dioxide
G6M87_00695	COG2902	Dehydrogenase
G6M87_00700	COG2270	Major facilitator Superfamily
G6M87_00705	COG0138	bifunctional purine biosynthesis protein purh
G6M87_00715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6M87_00715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G6M87_00720	COG0501	Belongs to the peptidase M48B family
G6M87_00730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6M87_00745	COG0495	leucyl-tRNA aminoacylation
G6M87_00770	COG0357	Ribosomal RNA small subunit methyltransferase G
G6M87_00775	COG0445	tRNA wobble uridine modification
G6M87_00780	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G6M87_00785	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
G6M87_00790	COG1981	membrane
G6M87_00795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G6M87_00800	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
G6M87_00805	COG0424	maF-like protein
G6M87_00810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6M87_00815	COG0237	dephospho-CoA kinase activity
G6M87_00830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G6M87_00845	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G6M87_00900	COG0135	phosphoribosylanthranilate isomerase activity
G6M87_00905	COG0133	tryptophan synthase activity
G6M87_00910	COG0159	tryptophan synthase activity
G6M87_00915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G6M87_00930	COG1074	ATP-dependent DNA helicase activity
G6M87_00940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6M87_00945	COG3178	'Phosphotransferase
G6M87_00950	COG2205	protein histidine kinase activity
G6M87_00955	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6M87_00960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6M87_00965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6M87_00965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G6M87_00975	COG0642	Histidine kinase
G6M87_00980	COG0745	RESPONSE REGULATOR receiver
G6M87_00985	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G6M87_01005	COG1072	(Pantothenic acid kinase))
G6M87_01010	COG0140	phosphoribosyl-ATP diphosphatase activity
G6M87_01015	COG0107	imidazoleglycerol-phosphate synthase activity
G6M87_01020	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G6M87_01025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6M87_01035	COG0131	Imidazoleglycerol-phosphate dehydratase
G6M87_01040	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G6M87_01045	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G6M87_01065	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G6M87_01085	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
G6M87_01095	COG1643	Atp-dependent helicase
G6M87_01100	COG2423	ornithine cyclodeaminase activity
G6M87_01250	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_01255	COG0673	inositol 2-dehydrogenase activity
G6M87_01260	COG3962	Belongs to the TPP enzyme family
G6M87_01270	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_01280	COG0673	inositol 2-dehydrogenase activity
G6M87_01295	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_01300	COG1129	ABC transporter
G6M87_01310	COG0673	inositol 2-dehydrogenase activity
G6M87_01315	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_01345	COG0395	ABC-type sugar transport system, permease component
G6M87_01365	COG3622	Belongs to the hyi family
G6M87_01370	COG1276	copper resistance
G6M87_01375	COG2372	response to copper ion
G6M87_01380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G6M87_01385	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_01390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6M87_01410	COG0539	negative regulation of cytoplasmic translation
G6M87_01415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G6M87_01420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6M87_01460	COG2860	membrane
G6M87_01470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6M87_01480	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6M87_01485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6M87_01500	COG1185	polyribonucleotide nucleotidyltransferase activity
G6M87_01505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G6M87_01510	COG2267	carboxylic ester hydrolase activity
G6M87_01515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G6M87_01520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G6M87_01525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G6M87_01540	COG0779	Required for maturation of 30S ribosomal subunits
G6M87_01545	COG2951	lytic endotransglycosylase activity
G6M87_01550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6M87_01565	COG1522	sequence-specific DNA binding
G6M87_01570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G6M87_01575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G6M87_01590	COG2816	NAD+ diphosphatase activity
G6M87_01595	COG2378	regulation of single-species biofilm formation
G6M87_01610	COG0077	Prephenate dehydratase
G6M87_01610	COG1605	Chorismate mutase
G6M87_01615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G6M87_01620	COG3474	cytochrome
G6M87_01630	COG0679	Auxin Efflux Carrier
G6M87_01635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_01655	COG2226	methyltransferase
G6M87_01670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G6M87_01675	COG0484	heat shock protein binding
G6M87_01680	COG0443	Heat shock 70 kDa protein
G6M87_01685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G6M87_01710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6M87_01720	COG1187	pseudouridine synthase activity
G6M87_01730	COG2205	protein histidine kinase activity
G6M87_01770	COG2972	Histidine kinase
G6M87_01770	COG0840	transmembrane signaling receptor activity
G6M87_01775	COG3842	ATPase activity
G6M87_01785	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_01795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6M87_01805	COG2199	diguanylate cyclase activity
G6M87_01805	COG2200	EAL domain
G6M87_01815	COG4957	zinc ion binding
G6M87_01820	COG0306	phosphate transporter
G6M87_01855	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G6M87_01860	COG1845	cytochrome c oxidase, subunit III
G6M87_01865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6M87_01870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6M87_01875	COG0477	Major facilitator Superfamily
G6M87_01890	COG3842	ATPase activity
G6M87_01895	COG1473	amidohydrolase
G6M87_01900	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6M87_01910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_01915	COG5001	Diguanylate cyclase
G6M87_01915	COG3300	MHYT domain
G6M87_01925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6M87_01925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G6M87_01930	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G6M87_01935	COG3454	Phosphonate metabolism
G6M87_01940	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G6M87_01945	COG3639	organic phosphonate transmembrane transporter activity
G6M87_01960	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G6M87_01975	COG4778	phosphonate C-P lyase system protein PhnL
G6M87_01980	COG4107	phosphonate C-P lyase system protein PhnK
G6M87_01985	COG3627	carbon phosphorus lyase activity
G6M87_01990	COG3626	phosphonate metabolism
G6M87_01995	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
G6M87_02000	COG3624	Phosphonate C-P lyase system protein PhnG
G6M87_02005	COG2188	Transcriptional regulator
G6M87_02010	COG0588	phosphoglycerate mutase activity
G6M87_02015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G6M87_02020	COG1132	(ABC) transporter
G6M87_02025	COG0837	glucose binding
G6M87_02030	COG1803	Methylglyoxal synthase
G6M87_02035	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
G6M87_02045	COG4166	transmembrane transport
G6M87_02050	COG4174	ABC transporter (Permease)
G6M87_02055	COG4239	(ABC) transporter, permease
G6M87_02060	COG4172	Belongs to the ABC transporter superfamily
G6M87_02065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_02070	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G6M87_02090	COG0668	transmembrane transport
G6M87_02105	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_02110	COG1902	pentaerythritol trinitrate reductase activity
G6M87_02115	COG2267	carboxylic ester hydrolase activity
G6M87_02145	COG0583	DNA-binding transcription factor activity
G6M87_02155	COG2814	Major facilitator Superfamily
G6M87_02165	COG0667	Aldo Keto reductase
G6M87_02170	COG0583	DNA-binding transcription factor activity
G6M87_02195	COG1744	ABC transporter substrate-binding protein PnrA-like
G6M87_02200	COG3845	ABC transporter
G6M87_02205	COG4603	Belongs to the binding-protein-dependent transport system permease family
G6M87_02210	COG1079	Belongs to the binding-protein-dependent transport system permease family
G6M87_02220	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
G6M87_02225	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G6M87_02230	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G6M87_02240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G6M87_02245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G6M87_02250	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G6M87_02290	COG4964	Belongs to the GSP D family
G6M87_02330	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6M87_02350	COG0154	amidase activity
G6M87_02355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_02365	COG0747	negative chemotaxis
G6M87_02385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6M87_02390	COG3038	cytochrome b561
G6M87_02405	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6M87_02430	COG0673	inositol 2-dehydrogenase activity
G6M87_02440	COG0395	ABC-type sugar transport system, permease component
G6M87_02450	COG3842	ATPase activity
G6M87_02475	COG1737	Transcriptional regulator
G6M87_02510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6M87_02530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6M87_02540	COG0481	GTPase activity
G6M87_02565	COG5006	permease, DMT superfamily
G6M87_02590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G6M87_02595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G6M87_02600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G6M87_02605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G6M87_02610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6M87_02610	COG0072	phenylalanine-tRNA ligase activity
G6M87_02620	COG4953	penicillin-binding protein 1C
G6M87_02630	COG0667	Aldo Keto reductase
G6M87_02635	COG0583	DNA-binding transcription factor activity
G6M87_02650	COG0667	Aldo Keto reductase
G6M87_02655	COG4977	sequence-specific DNA binding
G6M87_02690	COG1570	exodeoxyribonuclease VII activity
G6M87_02695	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6M87_02700	COG2309	aminopeptidase activity
G6M87_02720	COG1393	Belongs to the ArsC family
G6M87_02775	COG0583	DNA-binding transcription factor activity
G6M87_02780	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6M87_02790	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_02800	COG3663	DNA glycosylase
G6M87_02825	COG0583	DNA-binding transcription factor activity
G6M87_02830	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_02840	COG2020	methyltransferase activity
G6M87_02855	COG1309	transcriptional regulator
G6M87_02860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6M87_02860	COG0519	Catalyzes the synthesis of GMP from XMP
G6M87_02910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G6M87_02920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G6M87_02930	COG1968	undecaprenyl-diphosphatase activity
G6M87_02950	COG0284	orotidine-5'-phosphate decarboxylase activity
G6M87_02960	COG3963	phosphatidate phosphatase activity
G6M87_02970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G6M87_02975	COG0792	nuclease activity
G6M87_02990	COG0189	ligase activity
G6M87_03005	COG1280	lysine exporter protein (LysE YggA)
G6M87_03010	COG1335	isochorismatase
G6M87_03015	COG1280	lysine exporter protein (LysE YggA)
G6M87_03035	COG1522	sequence-specific DNA binding
G6M87_03045	COG0756	dUTP diphosphatase activity
G6M87_03050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6M87_03075	COG0667	Aldo Keto reductase
G6M87_03080	COG0583	DNA-binding transcription factor activity
G6M87_03085	COG1720	tRNA m6t6A37 methyltransferase activity
G6M87_03090	COG3585	molybdate ion transport
G6M87_03095	COG3119	arylsulfatase activity
G6M87_03100	COG0583	DNA-binding transcription factor activity
G6M87_03105	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G6M87_03110	COG1877	trehalose-phosphatase activity
G6M87_03120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G6M87_03130	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_03135	COG0583	DNA-binding transcription factor activity
G6M87_03140	COG0583	DNA-binding transcription factor activity
G6M87_03145	COG2814	Major facilitator Superfamily
G6M87_03170	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G6M87_03190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G6M87_03195	COG2986	histidine ammonia-lyase
G6M87_03205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6M87_03210	COG2226	methyltransferase
G6M87_03215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G6M87_03220	COG1024	Enoyl-CoA hydratase
G6M87_03225	COG0268	Binds directly to 16S ribosomal RNA
G6M87_03230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G6M87_03245	COG0697	spore germination
G6M87_03250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6M87_03255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G6M87_03265	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
G6M87_03270	COG1420	regulation of RNA biosynthetic process
G6M87_03280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G6M87_03285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6M87_03290	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G6M87_03300	COG1137	ATPase activity
G6M87_03305	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G6M87_03315	COG0616	signal peptide processing
G6M87_03320	COG0776	regulation of translation
G6M87_03345	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G6M87_03350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6M87_03355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G6M87_03375	COG0281	malic enzyme
G6M87_03375	COG0280	phosphate acetyltransferase
G6M87_03380	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G6M87_03410	COG0180	Tryptophanyl-tRNA synthetase
G6M87_03420	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G6M87_03445	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6M87_03450	COG1702	phosphate starvation-inducible protein PhoH
G6M87_03455	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G6M87_03465	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G6M87_03470	COG1396	sequence-specific DNA binding
G6M87_03475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G6M87_03480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G6M87_03490	COG0071	Belongs to the small heat shock protein (HSP20) family
G6M87_03500	COG0840	transmembrane signaling receptor activity
G6M87_03505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_03515	COG0242	peptide deformylase activity
G6M87_03530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G6M87_03535	COG0101	tRNA pseudouridine synthase activity
G6M87_03540	COG0579	oxidoreductase
G6M87_03550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_03555	COG2171	N-acyltransferase activity
G6M87_03565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6M87_03585	COG0300	oxidoreductase activity
G6M87_03590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G6M87_03605	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
G6M87_03610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G6M87_03615	COG2207	Transcriptional regulator
G6M87_03615	COG3708	Transcriptional regulator
G6M87_03625	COG0706	membrane insertase activity
G6M87_03630	COG0594	ribonuclease P activity
G6M87_03635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G6M87_03640	COG0840	transmembrane signaling receptor activity
G6M87_03640	COG2972	Histidine kinase
G6M87_03665	COG1733	regulation of RNA biosynthetic process
G6M87_03685	COG0477	Major facilitator Superfamily
G6M87_03705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6M87_03715	COG0583	DNA-binding transcription factor activity
G6M87_03720	COG0300	oxidoreductase activity
G6M87_03725	COG0667	Aldo Keto reductase
G6M87_03735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_03740	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_03745	COG3938	Belongs to the proline racemase family
G6M87_03775	COG1072	(Pantothenic acid kinase))
G6M87_03780	COG0418	dihydroorotase activity
G6M87_03790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6M87_03800	COG0166	Belongs to the GPI family
G6M87_03805	COG0318	PFAM AMP-dependent synthetase and ligase
G6M87_03815	COG0346	lactoylglutathione lyase activity
G6M87_03820	COG3795	YCII-related domain
G6M87_03825	COG1174	glycine betaine transport
G6M87_03830	COG1125	glycine betaine transport
G6M87_03835	COG1174	glycine betaine transport
G6M87_03840	COG1732	Glycine betaine
G6M87_03845	COG0583	DNA-binding transcription factor activity
G6M87_03945	COG2326	polyphosphate kinase activity
G6M87_03950	COG5002	protein histidine kinase activity
G6M87_03960	COG0573	inorganic phosphate transmembrane transporter activity
G6M87_03965	COG0581	inorganic phosphate transmembrane transporter activity
G6M87_03970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6M87_03975	COG0704	Plays a role in the regulation of phosphate uptake
G6M87_03980	COG0745	RESPONSE REGULATOR receiver
G6M87_03990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6M87_03995	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6M87_04000	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G6M87_04005	COG2967	ApaG domain
G6M87_04015	COG0717	Belongs to the dCTP deaminase family
G6M87_04025	COG0110	maltose O-acetyltransferase activity
G6M87_04060	COG0167	dihydroorotate dehydrogenase activity
G6M87_04065	COG0534	Mate efflux family protein
G6M87_04085	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
G6M87_04095	COG0174	glutamine synthetase
G6M87_04100	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6M87_04105	COG1959	2 iron, 2 sulfur cluster binding
G6M87_04110	COG1201	RNA secondary structure unwinding
G6M87_04135	COG0730	response to heat
G6M87_04150	COG1960	acyl-CoA dehydrogenase activity
G6M87_04155	COG0183	Belongs to the thiolase family
G6M87_04160	COG1024	Enoyl-CoA hydratase
G6M87_04160	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6M87_04175	COG1970	mechanosensitive ion channel activity
G6M87_04180	COG0436	Aminotransferase
G6M87_04225	COG1024	Enoyl-CoA hydratase
G6M87_04255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6M87_04255	COG4651	solute:proton antiporter activity
G6M87_04265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6M87_04270	COG0840	transmembrane signaling receptor activity
G6M87_04280	COG0745	RESPONSE REGULATOR receiver
G6M87_04285	COG0643	Histidine kinase
G6M87_04285	COG2198	Histidine kinase
G6M87_04290	COG0835	chemotaxis
G6M87_04295	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G6M87_04300	COG2201	protein-glutamate methylesterase activity
G6M87_04305	COG0745	RESPONSE REGULATOR receiver
G6M87_04310	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G6M87_04320	COG1766	The M ring may be actively involved in energy transduction
G6M87_04325	COG2771	luxR family
G6M87_04340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G6M87_04345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6M87_04350	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6M87_04355	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6M87_04360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G6M87_04365	COG4786	Flagellar basal body rod
G6M87_04370	COG1157	protein secretion by the type III secretion system
G6M87_04380	COG1815	bacterial-type flagellum-dependent cell motility
G6M87_04385	COG1558	bacterial-type flagellum-dependent cell motility
G6M87_04390	COG1677	Flagellar hook-basal body complex protein FliE
G6M87_04395	COG4786	Flagellar basal body rod
G6M87_04400	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
G6M87_04405	COG1706	bacterial-type flagellum-dependent cell motility
G6M87_04415	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G6M87_04425	COG1338	Plays a role in the flagellum-specific transport system
G6M87_04455	COG0076	glutamate decarboxylase activity
G6M87_04465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G6M87_04500	COG1749	Flagellar hook protein flgE
G6M87_04520	COG5443	negative regulation of bacterial-type flagellum assembly
G6M87_04530	COG4794	Type iii secretion
G6M87_04535	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G6M87_04540	COG1684	flagellar biosynthetic protein fliR
G6M87_04575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6M87_04580	COG1609	Transcriptional regulator
G6M87_04585	COG1653	transport
G6M87_04590	COG1175	transmembrane transport
G6M87_04595	COG0395	ABC-type sugar transport system, permease component
G6M87_04600	COG0366	Alpha amylase catalytic
G6M87_04605	COG3842	ATPase activity
G6M87_04625	COG0129	dihydroxy-acid dehydratase activity
G6M87_04630	COG0363	glucosamine-6-phosphate deaminase activity
G6M87_04635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6M87_04640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_04650	COG2081	HI0933 family
G6M87_04665	COG2972	Histidine kinase
G6M87_04665	COG0840	transmembrane signaling receptor activity
G6M87_04680	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G6M87_04685	COG3842	ATPase activity
G6M87_04690	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_04695	COG1177	transmembrane transport
G6M87_04705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6M87_04710	COG0513	Belongs to the DEAD box helicase family
G6M87_04720	COG2205	protein histidine kinase activity
G6M87_04760	COG4269	membrane
G6M87_04770	COG1959	2 iron, 2 sulfur cluster binding
G6M87_04775	COG0747	negative chemotaxis
G6M87_04780	COG0601	transmembrane transport
G6M87_04785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_04790	COG0444	Belongs to the ABC transporter superfamily
G6M87_04795	COG4608	Belongs to the ABC transporter superfamily
G6M87_04800	COG3265	gluconokinase activity
G6M87_04805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_04810	COG1755	Isoprenylcysteine carboxyl methyltransferase
G6M87_04825	COG1595	DNA-templated transcription, initiation
G6M87_04840	COG0583	DNA-binding transcription factor activity
G6M87_04850	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G6M87_04860	COG0477	Major facilitator Superfamily
G6M87_04890	COG0583	DNA-binding transcription factor activity
G6M87_04900	COG0488	(ABC) transporter
G6M87_04930	COG0306	phosphate transporter
G6M87_04945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6M87_04950	COG0583	DNA-binding transcription factor activity
G6M87_04955	COG0277	FAD linked oxidase domain protein
G6M87_04960	COG0277	FAD linked oxidase domain protein
G6M87_04965	COG0247	lactate metabolic process
G6M87_04980	COG1376	ErfK ybiS ycfS ynhG family protein
G6M87_04985	COG1376	ErfK ybiS ycfS ynhG family protein
G6M87_04990	COG2818	Glycosylase
G6M87_05005	COG0667	Aldo Keto reductase
G6M87_05010	COG0604	alcohol dehydrogenase
G6M87_05010	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_05010	COG3321	synthase
G6M87_05015	COG0583	DNA-binding transcription factor activity
G6M87_05055	COG0124	histidyl-tRNA synthetase
G6M87_05060	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
G6M87_05065	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6M87_05080	COG2259	Doxx family
G6M87_05085	COG0625	glutathione transferase activity
G6M87_05100	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6M87_05115	COG0196	riboflavin kinase activity
G6M87_05150	COG0590	tRNA wobble adenosine to inosine editing
G6M87_05155	COG1187	pseudouridine synthase activity
G6M87_05160	COG0742	ribosomal rna small subunit methyltransferase
G6M87_05170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6M87_05170	COG0475	glutathione-regulated potassium exporter activity
G6M87_05175	COG0312	modulator of DNA gyrase
G6M87_05180	COG0483	inositol monophosphate 1-phosphatase activity
G6M87_05190	COG1519	Transferase
G6M87_05200	COG1663	tetraacyldisaccharide 4'-kinase activity
G6M87_05210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G6M87_05215	COG0745	RESPONSE REGULATOR receiver
G6M87_05220	COG3300	MHYT domain
G6M87_05220	COG5001	Diguanylate cyclase
G6M87_05225	COG1522	sequence-specific DNA binding
G6M87_05230	COG0137	argininosuccinate synthase activity
G6M87_05240	COG3386	PFAM SMP-30 Gluconolaconase
G6M87_05245	COG0800	Aldolase
G6M87_05250	COG3734	2-keto-3-deoxy-galactonokinase
G6M87_05255	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_05260	COG1414	Transcriptional regulator
G6M87_05265	COG2197	response regulator
G6M87_05270	COG0489	protein tyrosine kinase activity
G6M87_05275	COG0598	Magnesium transport protein CorA
G6M87_05280	COG3158	transport of potassium into the cell
G6M87_05295	COG0356	it plays a direct role in the translocation of protons across the membrane
G6M87_05300	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6M87_05305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6M87_05310	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G6M87_05320	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6M87_05340	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6M87_05345	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G6M87_05355	COG0142	geranyltranstransferase activity
G6M87_05375	COG1396	sequence-specific DNA binding
G6M87_05410	COG0752	glycyl-tRNA synthetase alpha subunit
G6M87_05415	COG1704	LemA family
G6M87_05420	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6M87_05435	COG0751	glycine-tRNA ligase activity
G6M87_05440	COG1683	Conserved Protein
G6M87_05445	COG0840	transmembrane signaling receptor activity
G6M87_05455	COG0151	Belongs to the GarS family
G6M87_05460	COG2183	response to ionizing radiation
G6M87_05465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6M87_05485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6M87_05510	COG0277	FAD linked oxidase domain protein
G6M87_05515	COG0009	L-threonylcarbamoyladenylate synthase
G6M87_05530	COG4638	Rieske (2fe-2S)
G6M87_05555	COG1960	acyl-CoA dehydrogenase activity
G6M87_05565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G6M87_05575	COG0840	transmembrane signaling receptor activity
G6M87_05585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G6M87_05590	COG1741	Belongs to the pirin family
G6M87_05595	COG1722	exodeoxyribonuclease VII activity
G6M87_05600	COG0123	including yeast histone deacetylase and acetoin utilization protein
G6M87_05615	COG1268	BioY protein
G6M87_05620	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
G6M87_05625	COG1122	ATPase activity
G6M87_05630	COG3214	Protein conserved in bacteria
G6M87_05635	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6M87_05635	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6M87_05640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G6M87_05650	COG0406	alpha-ribazole phosphatase activity
G6M87_05655	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G6M87_05660	COG0484	heat shock protein binding
G6M87_05670	COG0259	pyridoxamine-phosphate oxidase activity
G6M87_05680	COG1686	Belongs to the peptidase S11 family
G6M87_05690	COG0312	modulator of DNA gyrase
G6M87_05700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6M87_05705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6M87_05710	COG0109	protoheme IX farnesyltransferase activity
G6M87_05720	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
G6M87_05730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6M87_05735	COG0640	Transcriptional regulator
G6M87_05760	COG3346	SURF1 family
G6M87_05765	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G6M87_05770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G6M87_05775	COG0328	RNA-DNA hybrid ribonuclease activity
G6M87_05790	COG0803	Belongs to the bacterial solute-binding protein 9 family
G6M87_05800	COG1121	(ABC) transporter
G6M87_05805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G6M87_05805	COG0678	peroxiredoxin activity
G6M87_05815	COG1678	Uncharacterized ACR, COG1678
G6M87_05835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6M87_05840	COG0612	Peptidase, M16
G6M87_05855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6M87_05865	COG1268	BioY protein
G6M87_05875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6M87_05895	COG2189	Belongs to the N(4) N(6)-methyltransferase family
G6M87_05910	COG1194	a g-specific adenine glycosylase
G6M87_05920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6M87_05925	COG1196	nuclear chromosome segregation
G6M87_05930	COG1253	flavin adenine dinucleotide binding
G6M87_05935	COG3093	addiction module antidote protein HigA
G6M87_05945	COG0574	Belongs to the PEP-utilizing enzyme family
G6M87_05945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6M87_06000	COG1956	GAF domain-containing protein
G6M87_06010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6M87_06030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G6M87_06045	COG0477	Major facilitator Superfamily
G6M87_06055	COG2895	sulfate adenylyltransferase (ATP) activity
G6M87_06060	COG0175	sulfate reduction
G6M87_06065	COG0175	sulfate reduction
G6M87_06070	COG1959	2 iron, 2 sulfur cluster binding
G6M87_06090	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G6M87_06095	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_06100	COG0625	glutathione transferase activity
G6M87_06105	COG1309	transcriptional regulator
G6M87_06120	COG4943	cyclic-guanylate-specific phosphodiesterase activity
G6M87_06125	COG1063	alcohol dehydrogenase
G6M87_06145	COG1349	DNA-binding transcription factor activity
G6M87_06155	COG0625	glutathione transferase activity
G6M87_06190	COG1960	acyl-CoA dehydrogenase activity
G6M87_06195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6M87_06235	COG1793	dna ligase
G6M87_06260	COG1376	ErfK ybiS ycfS ynhG family protein
G6M87_06265	COG1376	ErfK ybiS ycfS ynhG family protein
G6M87_06270	COG1846	Transcriptional regulator
G6M87_06275	COG1764	response to oxidative stress
G6M87_06290	COG1846	Transcriptional regulator
G6M87_06305	COG0433	COG0433 Predicted ATPase
G6M87_06325	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
G6M87_06330	COG4106	trans-aconitate 2-methyltransferase activity
G6M87_06340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6M87_06345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6M87_06355	COG2814	Major facilitator Superfamily
G6M87_06390	COG1278	Cold shock
G6M87_06395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6M87_06405	COG2207	Transcriptional regulator
G6M87_06410	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_06430	COG2010	Cytochrome c
G6M87_06435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6M87_06465	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6M87_06500	COG0484	heat shock protein binding
G6M87_06515	COG2514	catechol 2,3-dioxygenase activity
G6M87_06520	COG1272	protein, Hemolysin III
G6M87_06530	COG1247	-acetyltransferase
G6M87_06535	COG2111	Na H antiporter
G6M87_06535	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6M87_06540	COG2111	Na H antiporter
G6M87_06545	COG1006	Multisubunit Na H antiporter MnhC subunit
G6M87_06550	COG0651	ATP synthesis coupled electron transport
G6M87_06555	COG1863	multisubunit Na H antiporter MnhE subunit
G6M87_06560	COG2212	antiporter activity
G6M87_06565	COG1320	monovalent cation:proton antiporter activity
G6M87_06570	COG4957	zinc ion binding
G6M87_06575	COG2166	iron-sulfur cluster assembly
G6M87_06585	COG2205	protein histidine kinase activity
G6M87_06625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G6M87_06630	COG2983	Belongs to the UPF0260 family
G6M87_06660	COG4235	cytochrome complex assembly
G6M87_06665	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G6M87_06670	COG1138	Cytochrome C-type biogenesis protein
G6M87_06675	COG3088	subunit of a heme lyase
G6M87_06680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6M87_06685	COG0745	RESPONSE REGULATOR receiver
G6M87_06690	COG2205	protein histidine kinase activity
G6M87_06695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G6M87_06700	COG2202	Pas domain
G6M87_06700	COG2205	protein histidine kinase activity
G6M87_06705	COG0308	aminopeptidase N
G6M87_06710	COG3290	protein histidine kinase activity
G6M87_06710	COG0840	transmembrane signaling receptor activity
G6M87_06735	COG1573	uracil-dna glycosylase
G6M87_06740	COG0443	Heat shock 70 kDa protein
G6M87_06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_06755	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_06780	COG2239	Acts as a magnesium transporter
G6M87_06790	COG1733	regulation of RNA biosynthetic process
G6M87_06795	COG2814	Major facilitator Superfamily
G6M87_06805	COG0174	glutamine synthetase
G6M87_06820	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6M87_06825	COG0463	Glycosyl transferase, family 2
G6M87_06835	COG4941	Belongs to the sigma-70 factor family
G6M87_06845	COG3795	YCII-related domain
G6M87_06860	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G6M87_06885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6M87_06910	COG3718	enzyme involved in inositol metabolism
G6M87_06915	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_06920	COG3962	Belongs to the TPP enzyme family
G6M87_06925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_06935	COG0673	inositol 2-dehydrogenase activity
G6M87_06965	COG0798	PFAM Bile acid sodium symporter
G6M87_06975	COG0640	Transcriptional regulator
G6M87_06995	COG2945	thiolester hydrolase activity
G6M87_06995	COG0596	Alpha beta hydrolase
G6M87_07000	COG0741	lytic transglycosylase activity
G6M87_07005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_07010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G6M87_07020	COG1758	RNA polymerase activity
G6M87_07040	COG0736	holo-[acyl-carrier-protein] synthase activity
G6M87_07045	COG0681	Belongs to the peptidase S26 family
G6M87_07050	COG0571	ribonuclease III activity
G6M87_07055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6M87_07065	COG1381	Involved in DNA repair and RecF pathway recombination
G6M87_07075	COG1418	mRNA catabolic process
G6M87_07090	COG2032	superoxide dismutase activity
G6M87_07105	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G6M87_07110	COG0354	folic acid binding
G6M87_07135	COG1742	UPF0060 membrane protein
G6M87_07150	COG1183	phosphatidylcholine synthase activity
G6M87_07155	COG0688	phosphatidylethanolamine metabolic process
G6M87_07160	COG0671	phosphoesterase, PA-phosphatase related
G6M87_07165	COG5265	(ABC) transporter
G6M87_07185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6M87_07210	COG0215	cysteine-tRNA ligase activity
G6M87_07215	COG4221	oxidoreductase activity
G6M87_07220	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G6M87_07225	COG1286	toxin biosynthetic process
G6M87_07235	COG1280	lysine exporter protein (LysE YggA)
G6M87_07240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6M87_07245	COG0305	Participates in initiation and elongation during chromosome replication
G6M87_07265	COG0359	binds to the 23S rRNA
G6M87_07275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G6M87_07280	COG0360	Binds together with S18 to 16S ribosomal RNA
G6M87_07300	COG0667	Aldo Keto reductase
G6M87_07305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6M87_07315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6M87_07320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6M87_07325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6M87_07330	COG1561	YicC-like family, N-terminal region
G6M87_07335	COG0194	GDP metabolic process
G6M87_07340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6M87_07345	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G6M87_07355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G6M87_07370	COG0671	phosphoesterase, PA-phosphatase related
G6M87_07375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G6M87_07385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6M87_07400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G6M87_07400	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G6M87_07405	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G6M87_07410	COG1505	serine-type exopeptidase activity
G6M87_07420	COG0488	(ABC) transporter
G6M87_07435	COG0105	UTP biosynthetic process
G6M87_07455	COG0314	molybdopterin synthase activity
G6M87_07465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6M87_07470	COG0322	excinuclease ABC activity
G6M87_07475	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_07485	COG0625	glutathione transferase activity
G6M87_07490	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G6M87_07495	COG0243	molybdopterin cofactor binding
G6M87_07505	COG3454	Phosphonate metabolism
G6M87_07510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G6M87_07515	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G6M87_07520	COG0628	permease
G6M87_07530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G6M87_07535	COG0248	Ppx GppA phosphatase
G6M87_07545	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6M87_07550	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
G6M87_07555	COG2132	Multicopper oxidase
G6M87_07560	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G6M87_07580	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6M87_07585	COG3654	unkown
G6M87_07600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G6M87_07610	COG0113	porphobilinogen synthase activity
G6M87_07630	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6M87_07635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G6M87_07640	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6M87_07640	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6M87_07650	COG0454	-acetyltransferase
G6M87_07665	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6M87_07670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G6M87_07675	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G6M87_07695	COG0416	fatty acid biosynthetic process
G6M87_07700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G6M87_07705	COG0776	regulation of translation
G6M87_07760	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
G6M87_07765	COG4423	Transcription factor
G6M87_07775	COG0438	transferase activity, transferring glycosyl groups
G6M87_07815	COG1612	heme a metabolic process
G6M87_07825	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G6M87_07830	COG0010	Belongs to the arginase family
G6M87_07845	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G6M87_07850	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G6M87_07865	COG1832	CoA-binding protein
G6M87_07885	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G6M87_07890	COG0573	inorganic phosphate transmembrane transporter activity
G6M87_07900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6M87_07905	COG2124	cytochrome p450
G6M87_07910	COG3706	GGDEF domain
G6M87_07915	COG0740	serine-type endopeptidase activity
G6M87_07920	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G6M87_07925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G6M87_07930	COG0776	regulation of translation
G6M87_07935	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_07940	COG0667	Aldo Keto reductase
G6M87_07945	COG0420	3'-5' exonuclease activity
G6M87_07950	COG4717	serine-type aminopeptidase activity
G6M87_07960	COG1216	Glycosyl transferase, family 2
G6M87_07960	COG0438	transferase activity, transferring glycosyl groups
G6M87_07965	COG0604	alcohol dehydrogenase
G6M87_07965	COG3321	synthase
G6M87_07985	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6M87_07990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6M87_07995	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6M87_08000	COG0649	NAD binding
G6M87_08010	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
G6M87_08015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6M87_08020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6M87_08020	COG3743	rRNA binding
G6M87_08030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G6M87_08035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6M87_08045	COG0713	ATP synthesis coupled electron transport
G6M87_08060	COG1007	ATP synthesis coupled electron transport
G6M87_08075	COG0346	lactoylglutathione lyase activity
G6M87_08090	COG0442	prolyl-tRNA aminoacylation
G6M87_08100	COG1136	(ABC) transporter
G6M87_08130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6M87_08150	COG0784	Response regulator, receiver
G6M87_08160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G6M87_08165	COG2814	Major facilitator Superfamily
G6M87_08180	COG0557	exoribonuclease II activity
G6M87_08185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G6M87_08190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6M87_08190	COG0758	DNA mediated transformation
G6M87_08195	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G6M87_08205	COG0540	Belongs to the ATCase OTCase family
G6M87_08210	COG1960	acyl-CoA dehydrogenase activity
G6M87_08215	COG3609	addiction module antidote protein, CC2985 family
G6M87_08225	COG0456	acetyltransferase
G6M87_08245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6M87_08250	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G6M87_08255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6M87_08260	COG0154	amidase activity
G6M87_08270	COG3811	Belongs to the UPF0386 family
G6M87_08280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6M87_08300	COG4765	Protein conserved in bacteria
G6M87_08315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G6M87_08330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6M87_08340	COG0436	Aminotransferase
G6M87_08345	COG1530	ribonuclease E activity
G6M87_08350	COG0860	N-Acetylmuramoyl-L-alanine amidase
G6M87_08355	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G6M87_08365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6M87_08460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6M87_08485	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6M87_08490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6M87_08515	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6M87_08525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G6M87_08530	COG0081	regulation of translation
G6M87_08535	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G6M87_08540	COG0222	ribosome binding
G6M87_08545	COG0085	RNA polymerase activity
G6M87_08550	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G6M87_08560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G6M87_08565	COG0049	tRNA binding
G6M87_08570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G6M87_08575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G6M87_08580	COG0051	transcription antitermination factor activity, RNA binding
G6M87_08585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G6M87_08590	COG0088	Forms part of the polypeptide exit tunnel
G6M87_08595	COG0089	rRNA binding
G6M87_08600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G6M87_08605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G6M87_08610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G6M87_08615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G6M87_08620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G6M87_08625	COG0255	Belongs to the universal ribosomal protein uL29 family
G6M87_08630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G6M87_08635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G6M87_08640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G6M87_08645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G6M87_08650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G6M87_08655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G6M87_08660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G6M87_08665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G6M87_08670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G6M87_08675	COG1841	ribosomal large subunit assembly
G6M87_08680	COG0200	Binds to the 23S rRNA
G6M87_08685	COG0201	protein transport
G6M87_08690	COG0563	adenylate kinase activity
G6M87_08695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G6M87_08700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G6M87_08705	COG0202	RNA polymerase activity
G6M87_08710	COG0203	ribosomal protein L17
G6M87_08715	COG3739	integral membrane protein
G6M87_08730	COG1289	transmembrane transporter activity
G6M87_08740	COG1566	PFAM secretion protein HlyD family protein
G6M87_08745	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G6M87_08750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6M87_08755	COG0129	dihydroxy-acid dehydratase activity
G6M87_08770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G6M87_08790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_08810	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G6M87_08835	COG0488	(ABC) transporter
G6M87_08840	COG1253	flavin adenine dinucleotide binding
G6M87_08865	COG0789	Transcriptional regulator
G6M87_08880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6M87_08890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6M87_08895	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G6M87_08905	COG1058	Belongs to the CinA family
G6M87_08905	COG1546	Belongs to the CinA family
G6M87_08910	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6M87_08920	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G6M87_08935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G6M87_08950	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_08960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6M87_08965	COG0583	DNA-binding transcription factor activity
G6M87_08970	COG0737	Belongs to the 5'-nucleotidase family
G6M87_08985	COG1522	sequence-specific DNA binding
G6M87_08990	COG0686	Belongs to the AlaDH PNT family
G6M87_09005	COG2897	thiosulfate sulfurtransferase activity
G6M87_09010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6M87_09015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6M87_09020	COG0300	oxidoreductase activity
G6M87_09025	COG3842	ATPase activity
G6M87_09030	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6M87_09035	COG0395	ABC-type sugar transport system, permease component
G6M87_09040	COG1175	transmembrane transport
G6M87_09045	COG1653	transport
G6M87_09130	COG0328	RNA-DNA hybrid ribonuclease activity
G6M87_09285	COG3179	chitinase
G6M87_09365	COG2755	lipolytic protein G-D-S-L family
G6M87_09365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6M87_09370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G6M87_09380	COG0525	valine-tRNA ligase activity
G6M87_09400	COG0316	Belongs to the HesB IscA family
G6M87_09405	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G6M87_09410	COG0018	arginyl-trna synthetase
G6M87_09420	COG1472	Belongs to the glycosyl hydrolase 3 family
G6M87_09425	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6M87_09435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6M87_09440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G6M87_09445	COG0805	protein transport
G6M87_09450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G6M87_09455	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G6M87_09460	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G6M87_09475	COG1862	Preprotein translocase
G6M87_09500	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
G6M87_09530	COG0544	peptidyl-prolyl cis-trans isomerase activity
G6M87_09550	COG2003	Belongs to the UPF0758 family
G6M87_09555	COG0024	Methionine aminopeptidase
G6M87_09560	COG1489	DNA binding
G6M87_09565	COG3243	poly(R)-hydroxyalkanoic acid synthase
G6M87_09575	COG0436	Aminotransferase
G6M87_09650	COG1278	Cold shock
G6M87_09680	COG1280	lysine exporter protein (LysE YggA)
G6M87_09685	COG1522	sequence-specific DNA binding
G6M87_09695	COG1126	abc transporter atp-binding protein
G6M87_09700	COG0765	amino acid transport
G6M87_09705	COG4597	amino acid ABC transporter
G6M87_09710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_09720	COG0626	cystathionine gamma-synthase activity
G6M87_09735	COG0596	Alpha beta hydrolase
G6M87_09760	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G6M87_09770	COG0537	adenosine 5'-monophosphoramidase activity
G6M87_09795	COG0052	Belongs to the universal ribosomal protein uS2 family
G6M87_09800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G6M87_09805	COG0528	UMP kinase activity
G6M87_09810	COG0233	cytoplasmic translational termination
G6M87_09815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6M87_09825	COG0750	zinc metalloprotease
G6M87_09830	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6M87_09835	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6M87_09840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G6M87_09845	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6M87_09850	COG3494	Protein of unknown function (DUF1009)
G6M87_09855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6M87_09870	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6M87_09880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G6M87_09885	COG0148	phosphopyruvate hydratase activity
G6M87_09895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6M87_09900	COG0022	dehydrogenase e1 component
G6M87_09900	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6M87_09905	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6M87_09915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6M87_09930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6M87_09945	COG2867	negative regulation of translational initiation
G6M87_09950	COG1546	Belongs to the CinA family
G6M87_09955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
G6M87_09955	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G6M87_09965	COG3852	Histidine kinase
G6M87_09970	COG2204	response regulator
G6M87_09975	COG5000	phosphorelay sensor kinase activity
G6M87_09980	COG2204	response regulator
G6M87_09985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6M87_09990	COG1923	regulation of RNA biosynthetic process
G6M87_09995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6M87_10000	COG3956	TIGRFAM MazG family protein
G6M87_10010	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6M87_10010	COG1648	precorrin-2 dehydrogenase activity
G6M87_10020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6M87_10060	COG0785	Cytochrome C biogenesis protein
G6M87_10065	COG0679	Auxin Efflux Carrier
G6M87_10070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6M87_10075	COG1183	phosphatidylcholine synthase activity
G6M87_10085	COG3845	ABC transporter
G6M87_10090	COG4603	Belongs to the binding-protein-dependent transport system permease family
G6M87_10095	COG1079	Belongs to the binding-protein-dependent transport system permease family
G6M87_10105	COG1879	ABC-type sugar transport system periplasmic component
G6M87_10110	COG1129	ABC transporter
G6M87_10115	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_10120	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_10125	COG2186	Transcriptional regulator
G6M87_10130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G6M87_10135	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6M87_10155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6M87_10165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G6M87_10180	COG0583	DNA-binding transcription factor activity
G6M87_10205	COG0174	glutamine synthetase
G6M87_10210	COG0347	Belongs to the P(II) protein family
G6M87_10215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G6M87_10215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G6M87_10225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G6M87_10230	COG0629	single-stranded DNA binding
G6M87_10235	COG2095	MarC family integral membrane protein
G6M87_10240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
G6M87_10265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G6M87_10280	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G6M87_10285	COG0343	queuine tRNA-ribosyltransferase activity
G6M87_10315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6M87_10330	COG1132	(ABC) transporter
G6M87_10335	COG1132	(ABC) transporter
G6M87_10340	COG0583	DNA-binding transcription factor activity
G6M87_10360	COG0321	lipoyl(octanoyl) transferase activity
G6M87_10360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G6M87_10365	COG0084	hydrolase, TatD family'
G6M87_10370	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6M87_10375	COG0730	response to heat
G6M87_10385	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G6M87_10405	COG0582	viral genome integration into host DNA
G6M87_10485	COG2094	Belongs to the DNA glycosylase MPG family
G6M87_10515	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6M87_10520	COG0134	indole-3-glycerol-phosphate synthase activity
G6M87_10525	COG0315	cyclic pyranopterin monophosphate synthase activity
G6M87_10535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
G6M87_10545	COG0372	Belongs to the citrate synthase family
G6M87_10550	COG0372	Belongs to the citrate synthase family
G6M87_10555	COG0583	DNA-binding transcription factor activity
G6M87_10575	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
G6M87_10590	COG0504	CTP synthase activity
G6M87_10595	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G6M87_10600	COG0149	triose-phosphate isomerase activity
G6M87_10610	COG0187	DNA topoisomerase II activity
G6M87_10620	COG0628	permease
G6M87_10655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G6M87_10665	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G6M87_10675	COG0302	gtp cyclohydrolase
G6M87_10680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6M87_10685	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6M87_10710	COG2267	carboxylic ester hydrolase activity
G6M87_10725	COG1686	Belongs to the peptidase S11 family
G6M87_10745	COG1760	l-serine dehydratase
G6M87_10770	COG2239	Acts as a magnesium transporter
G6M87_10775	COG0242	peptide deformylase activity
G6M87_10845	COG0556	nucleotide-excision repair
G6M87_10870	COG3750	Belongs to the UPF0335 family
G6M87_10915	COG0500	methyltransferase
G6M87_11000	COG0740	serine-type endopeptidase activity
G6M87_11010	COG1802	Transcriptional regulator
G6M87_11010	COG4626	Terminase
G6M87_11070	COG1475	DNA binding
G6M87_11125	COG0321	lipoyl(octanoyl) transferase activity
G6M87_11140	COG4770	biotin carboxylase activity
G6M87_11145	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G6M87_11150	COG1671	Belongs to the UPF0178 family
G6M87_11155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
G6M87_11165	COG2259	Doxx family
G6M87_11170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6M87_11185	COG0546	phosphoglycolate phosphatase activity
G6M87_11205	COG0509	glycine decarboxylation via glycine cleavage system
G6M87_11210	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6M87_11210	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G6M87_11220	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6M87_11235	COG0316	Belongs to the HesB IscA family
G6M87_11240	COG2151	metal-sulfur cluster biosynthetic enzyme
G6M87_11245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6M87_11250	COG0719	Fe-S assembly protein
G6M87_11255	COG0396	ATPase activity
G6M87_11265	COG0719	Fe-S assembly protein
G6M87_11275	COG2945	thiolester hydrolase activity
G6M87_11290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G6M87_11295	COG0346	lactoylglutathione lyase activity
G6M87_11305	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6M87_11310	COG2833	Protein of unknown function (DUF455)
G6M87_11315	COG1196	nuclear chromosome segregation
G6M87_11315	COG0741	lytic transglycosylase activity
G6M87_11315	COG0739	heme binding
G6M87_11320	COG0513	Belongs to the DEAD box helicase family
G6M87_11325	COG1051	belongs to the nudix hydrolase family
G6M87_11335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G6M87_11340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
G6M87_11340	COG3608	succinylglutamate desuccinylase aspartoacylase
G6M87_11355	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G6M87_11360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6M87_11380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6M87_11400	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G6M87_11405	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6M87_11410	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
G6M87_11415	COG0047	phosphoribosylformylglycinamidine synthase activity
G6M87_11435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6M87_11445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6M87_11470	COG2814	Major facilitator Superfamily
G6M87_11475	COG2814	Major facilitator Superfamily
G6M87_11485	COG0483	inositol monophosphate 1-phosphatase activity
G6M87_11490	COG0483	inositol monophosphate 1-phosphatase activity
G6M87_11495	COG0037	tRNA processing
G6M87_11500	COG2066	Belongs to the glutaminase family
G6M87_11505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G6M87_11515	COG1304	FMN binding
G6M87_11525	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6M87_11540	COG0538	isocitrate dehydrogenase activity
G6M87_11555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G6M87_11560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G6M87_11570	COG2313	pseudouridylate synthase activity
G6M87_11605	COG3106	COG3106 Predicted ATPase
G6M87_11610	COG3768	UPF0283 membrane protein
G6M87_11630	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G6M87_11640	COG0633	Ferredoxin
G6M87_11670	COG3507	Belongs to the glycosyl hydrolase 43 family
G6M87_11675	COG0667	Aldo Keto reductase
G6M87_11680	COG0673	inositol 2-dehydrogenase activity
G6M87_11700	COG0395	ABC-type sugar transport system, permease component
G6M87_11705	COG1175	transmembrane transport
G6M87_11720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
G6M87_11740	COG1127	ABC transporter
G6M87_11745	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6M87_11750	COG2814	Major facilitator Superfamily
G6M87_11760	COG0281	malic enzyme
G6M87_11760	COG0280	phosphate acetyltransferase
G6M87_11775	COG0823	Involved in the tonB-independent uptake of proteins
G6M87_11785	COG1368	sulfuric ester hydrolase activity
G6M87_11810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
G6M87_11825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G6M87_11830	COG0546	phosphoglycolate phosphatase activity
G6M87_11835	COG2989	Protein conserved in bacteria
G6M87_11840	COG0114	fumarate hydratase activity
G6M87_11850	COG3706	GGDEF domain
G6M87_11865	COG1846	Transcriptional regulator
G6M87_11880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6M87_11890	COG2972	Histidine kinase
G6M87_11890	COG0840	transmembrane signaling receptor activity
G6M87_11895	COG0697	spore germination
G6M87_11900	COG0746	molybdenum cofactor guanylyltransferase activity
G6M87_11905	COG1763	Mo-molybdopterin cofactor biosynthetic process
G6M87_11915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_11930	COG5425	PFAM Usg family protein
G6M87_11945	COG0640	Transcriptional regulator
G6M87_11955	COG1116	anion transmembrane transporter activity
G6M87_11960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_11965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_11970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_11975	COG2084	Dehydrogenase
G6M87_11980	COG1522	sequence-specific DNA binding
G6M87_11985	COG1573	uracil-dna glycosylase
G6M87_11995	COG2205	protein histidine kinase activity
G6M87_11995	COG2202	Pas domain
G6M87_12005	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6M87_12010	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
G6M87_12025	COG0697	spore germination
G6M87_12040	COG0842	Transport permease protein
G6M87_12045	COG1131	(ABC) transporter
G6M87_12060	COG1607	acyl-coa hydrolase
G6M87_12090	COG2814	Major facilitator Superfamily
G6M87_12095	COG0556	nucleotide-excision repair
G6M87_12110	COG1278	Cold shock
G6M87_12115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G6M87_12120	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6M87_12135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6M87_12140	COG1121	(ABC) transporter
G6M87_12150	COG0523	cobalamin synthesis protein
G6M87_12175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6M87_12190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6M87_12250	COG1917	Cupin 2, conserved barrel domain protein
G6M87_12275	COG1492	cobalamin metabolic process
G6M87_12290	COG4176	ABC-type proline glycine betaine transport system permease component
G6M87_12295	COG4175	Glycine betaine
G6M87_12295	COG0517	IMP dehydrogenase activity
G6M87_12300	COG1410	methionine synthase
G6M87_12300	COG0646	methionine synthase
G6M87_12310	COG0463	Glycosyl transferase, family 2
G6M87_12325	COG5598	trimethylamine methyltransferase
G6M87_12330	COG5012	cobalamin binding
G6M87_12360	COG0646	methionine synthase
G6M87_12360	COG1410	methionine synthase
G6M87_12380	COG0583	DNA-binding transcription factor activity
G6M87_12405	COG0745	RESPONSE REGULATOR receiver
G6M87_12410	COG3264	Mechanosensitive ion channel
G6M87_12410	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G6M87_12435	COG1959	2 iron, 2 sulfur cluster binding
G6M87_12450	COG0384	phenazine biosynthesis protein PhzF
G6M87_12465	COG3842	ATPase activity
G6M87_12480	COG0667	Aldo Keto reductase
G6M87_12485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6M87_12500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6M87_12510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G6M87_12520	COG2207	Transcriptional regulator
G6M87_12525	COG1064	alcohol dehydrogenase
G6M87_12530	COG1252	NADH dehydrogenase
G6M87_12540	COG1522	sequence-specific DNA binding
G6M87_12545	COG1794	racemase activity, acting on amino acids and derivatives
G6M87_12555	COG0456	acetyltransferase
G6M87_12565	COG2814	Major facilitator Superfamily
G6M87_12570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6M87_12575	COG1733	regulation of RNA biosynthetic process
G6M87_12585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G6M87_12590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6M87_12625	COG0656	L-ascorbic acid biosynthetic process
G6M87_12635	COG0440	acetolactate synthase activity
G6M87_12640	COG0028	Belongs to the TPP enzyme family
G6M87_12650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G6M87_12655	COG0560	Phosphoserine phosphatase
G6M87_12665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6M87_12675	COG0330	HflC and HflK could
G6M87_12690	COG0463	Glycosyl transferase, family 2
G6M87_12700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6M87_12710	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G6M87_12730	COG0410	ABC transporter
G6M87_12745	COG0583	DNA-binding transcription factor activity
G6M87_12760	COG3238	Protein conserved in bacteria
G6M87_12770	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G6M87_12800	COG0277	FAD linked oxidase domain protein
G6M87_12805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_12810	COG0765	amino acid transport
G6M87_12815	COG0765	amino acid transport
G6M87_12835	COG2885	chlorophyll binding
G6M87_12840	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G6M87_12845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6M87_12850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_12855	COG0210	DNA helicase
G6M87_12875	COG1335	isochorismatase
G6M87_12890	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G6M87_12895	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6M87_12915	COG0006	proline dipeptidase activity
G6M87_12925	COG2264	protein methyltransferase activity
G6M87_12935	COG1999	signal sequence binding
G6M87_12940	COG0835	chemotaxis
G6M87_12955	COG1247	-acetyltransferase
G6M87_12960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G6M87_12970	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6M87_12980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6M87_12985	COG0849	cell division
G6M87_12990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6M87_12995	COG1181	Belongs to the D-alanine--D-alanine ligase family
G6M87_13000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G6M87_13005	COG0477	Major facilitator Superfamily
G6M87_13010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G6M87_13015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6M87_13020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G6M87_13030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G6M87_13035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G6M87_13045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6M87_13060	COG0275	rRNA processing
G6M87_13065	COG2001	Belongs to the MraZ family
G6M87_13085	COG3023	N-Acetylmuramoyl-L-alanine amidase
G6M87_13100	COG1280	lysine exporter protein (LysE YggA)
G6M87_13120	COG4106	trans-aconitate 2-methyltransferase activity
G6M87_13135	COG0697	spore germination
G6M87_13145	COG2226	methyltransferase
G6M87_13170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6M87_13175	COG0028	Belongs to the TPP enzyme family
G6M87_13180	COG0251	oxidation-reduction process
G6M87_13195	COG1376	ErfK ybiS ycfS ynhG family protein
G6M87_13205	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_13210	COG0174	glutamine synthetase
G6M87_13240	COG2011	ABC-type metal ion transport system permease component
G6M87_13245	COG3842	ATPase activity
G6M87_13250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G6M87_13260	COG1609	Transcriptional regulator
G6M87_13270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6M87_13280	COG0673	inositol 2-dehydrogenase activity
G6M87_13285	COG0395	ABC-type sugar transport system, permease component
G6M87_13290	COG1175	transmembrane transport
G6M87_13300	COG2971	BadF BadG BcrA BcrD
G6M87_13305	COG2188	Transcriptional regulator
G6M87_13320	COG4702	Belongs to the UPF0303 family
G6M87_13335	COG0438	transferase activity, transferring glycosyl groups
G6M87_13390	COG2264	protein methyltransferase activity
G6M87_13445	COG2968	Membrane
G6M87_13460	COG0432	Pfam Uncharacterised protein family UPF0047
G6M87_13465	COG5507	3-demethylubiquinone-9 3-methyltransferase
G6M87_13485	COG0072	phenylalanine-tRNA ligase activity
G6M87_13485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6M87_13490	COG2207	Transcriptional regulator
G6M87_13490	COG1917	Cupin 2, conserved barrel domain protein
G6M87_13510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6M87_13515	COG1063	alcohol dehydrogenase
G6M87_13525	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_13530	COG0514	ATP-dependent DNA helicase (RecQ)
G6M87_13535	COG0358	DNA primase activity
G6M87_13550	COG0505	Belongs to the CarA family
G6M87_13560	COG0534	Mate efflux family protein
G6M87_13570	COG2321	neutral zinc metallopeptidase
G6M87_13585	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G6M87_13590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6M87_13610	COG1522	sequence-specific DNA binding
G6M87_13615	COG0492	ferredoxin-NADP+ reductase activity
G6M87_13620	COG0583	DNA-binding transcription factor activity
G6M87_13630	COG1902	pentaerythritol trinitrate reductase activity
G6M87_13640	COG0300	oxidoreductase activity
G6M87_13645	COG0583	DNA-binding transcription factor activity
G6M87_13655	COG0387	Pfam Sodium calcium exchanger
G6M87_13665	COG2133	pyrroloquinoline quinone binding
G6M87_13675	COG1278	Cold shock
G6M87_13685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6M87_13700	COG1846	Transcriptional regulator
G6M87_13705	COG0745	RESPONSE REGULATOR receiver
G6M87_13710	COG2205	protein histidine kinase activity
G6M87_13720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6M87_13740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G6M87_13750	COG1496	oxidoreductase activity
G6M87_13765	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6M87_13785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G6M87_13800	COG0193	aminoacyl-tRNA hydrolase activity
G6M87_13810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G6M87_13830	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6M87_13835	COG2857	Cytochrome c1
G6M87_13835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G6M87_13855	COG1132	(ABC) transporter
G6M87_13860	COG1132	(ABC) transporter
G6M87_13865	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6M87_13885	COG0408	coproporphyrinogen oxidase activity
G6M87_13900	COG0617	tRNA 3'-terminal CCA addition
G6M87_13915	COG0714	Associated with various cellular activities
G6M87_13935	COG0454	-acetyltransferase
G6M87_13950	COG0435	Glutathione S-transferase
G6M87_13990	COG1132	(ABC) transporter
G6M87_13995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6M87_14000	COG3135	benzoate transporter
G6M87_14005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6M87_14015	COG0740	serine-type endopeptidase activity
G6M87_14025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G6M87_14030	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G6M87_14035	COG0778	Nitroreductase
G6M87_14045	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6M87_14045	COG0512	Glutamine amidotransferase of anthranilate synthase
G6M87_14050	COG0488	(ABC) transporter
G6M87_14065	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G6M87_14070	COG2862	Uncharacterized protein family, UPF0114
G6M87_14085	COG2197	response regulator
G6M87_14110	COG1435	thymidine kinase activity
G6M87_14120	COG4176	ABC-type proline glycine betaine transport system permease component
G6M87_14125	COG4175	Glycine betaine
G6M87_14140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6M87_14145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6M87_14150	COG0366	Alpha amylase catalytic
G6M87_14160	COG0601	transmembrane transport
G6M87_14165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_14175	COG4608	Belongs to the ABC transporter superfamily
G6M87_14180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_14200	COG1846	Transcriptional regulator
G6M87_14205	COG1160	GTP binding
G6M87_14225	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G6M87_14235	COG0024	Methionine aminopeptidase
G6M87_14255	COG4941	Belongs to the sigma-70 factor family
G6M87_14260	COG3795	YCII-related domain
G6M87_14270	COG1619	proteins homologs of microcin C7 resistance protein MccF
G6M87_14280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6M87_14285	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_14295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6M87_14310	COG0583	DNA-binding transcription factor activity
G6M87_14325	COG0402	S-adenosylhomocysteine deaminase activity
G6M87_14340	COG2351	hydroxyisourate hydrolase activity
G6M87_14345	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G6M87_14365	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
G6M87_14370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_14375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_14375	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G6M87_14380	COG0784	Response regulator, receiver
G6M87_14380	COG2205	protein histidine kinase activity
G6M87_14380	COG5002	protein histidine kinase activity
G6M87_14385	COG5598	trimethylamine methyltransferase
G6M87_14395	COG0513	Belongs to the DEAD box helicase family
G6M87_14410	COG2308	Evidence 4 Homologs of previously reported genes of
G6M87_14430	COG1132	(ABC) transporter
G6M87_14435	COG0129	dihydroxy-acid dehydratase activity
G6M87_14440	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_14450	COG4214	carbohydrate transport
G6M87_14480	COG0673	inositol 2-dehydrogenase activity
G6M87_14490	COG4213	ABC transporter substrate-binding protein
G6M87_14495	COG4214	carbohydrate transport
G6M87_14500	COG1129	ABC transporter
G6M87_14540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6M87_14560	COG0671	phosphoesterase, PA-phosphatase related
G6M87_14570	COG2194	sulfuric ester hydrolase activity
G6M87_14595	COG0406	alpha-ribazole phosphatase activity
G6M87_14640	COG0022	dehydrogenase e1 component
G6M87_14650	COG0038	chloride channel
G6M87_14670	COG2076	Multidrug Resistance protein
G6M87_14680	COG3842	ATPase activity
G6M87_14685	COG3833	ABC-type maltose transport systems, permease component
G6M87_14705	COG0673	inositol 2-dehydrogenase activity
G6M87_14710	COG1609	Transcriptional regulator
G6M87_14760	COG4558	Periplasmic binding protein
G6M87_14765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6M87_14770	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
G6M87_14795	COG0784	Response regulator, receiver
G6M87_14800	COG2202	Pas domain
G6M87_14800	COG3920	Histidine kinase
G6M87_14805	COG0493	'glutamate synthase
G6M87_14815	COG1309	transcriptional regulator
G6M87_14845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_14850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_14855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_14860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_14870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G6M87_14875	COG0830	nickel cation binding
G6M87_14880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
G6M87_14885	COG3706	GGDEF domain
G6M87_14895	COG0804	urea catabolic process
G6M87_14900	COG1442	glycosyl transferase family 8
G6M87_14905	COG0832	Belongs to the urease beta subunit family
G6M87_14910	COG0831	urea catabolic process
G6M87_14915	COG0829	nickel cation binding
G6M87_14925	COG0411	ABC transporter
G6M87_14935	COG0559	Belongs to the binding-protein-dependent transport system permease family
G6M87_14945	COG0784	Response regulator, receiver
G6M87_14945	COG2198	Histidine kinase
G6M87_14945	COG5002	protein histidine kinase activity
G6M87_14950	COG0745	RESPONSE REGULATOR receiver
G6M87_14955	COG0683	leucine binding
G6M87_14990	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6M87_14995	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6M87_14995	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6M87_15000	COG4311	Sarcosine oxidase, delta subunit
G6M87_15005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_15065	COG0564	pseudouridine synthase activity
G6M87_15070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G6M87_15080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6M87_15090	COG0402	S-adenosylhomocysteine deaminase activity
G6M87_15095	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6M87_15100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6M87_15105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6M87_15120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_15130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_15135	COG0402	S-adenosylhomocysteine deaminase activity
G6M87_15145	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6M87_15165	COG0346	lactoylglutathione lyase activity
G6M87_15170	COG0251	oxidation-reduction process
G6M87_15195	COG0346	lactoylglutathione lyase activity
G6M87_15200	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G6M87_15205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6M87_15220	COG1349	DNA-binding transcription factor activity
G6M87_15225	COG0583	DNA-binding transcription factor activity
G6M87_15230	COG2855	membrane
G6M87_15235	COG5001	Diguanylate cyclase
G6M87_15235	COG3300	MHYT domain
G6M87_15240	COG0129	dihydroxy-acid dehydratase activity
G6M87_15245	COG2084	Dehydrogenase
G6M87_15250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6M87_15270	COG0583	DNA-binding transcription factor activity
G6M87_15280	COG1595	DNA-templated transcription, initiation
G6M87_15290	COG0697	spore germination
G6M87_15300	COG1846	Transcriptional regulator
G6M87_15320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6M87_15325	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_15330	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_15375	COG0477	Major facilitator Superfamily
G6M87_15385	COG1278	Cold shock
G6M87_15395	COG0346	lactoylglutathione lyase activity
G6M87_15405	COG4948	Mandelate Racemase Muconate Lactonizing
G6M87_15440	COG2011	ABC-type metal ion transport system permease component
G6M87_15450	COG4521	taurine ABC transporter
G6M87_15460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_15465	COG0330	HflC and HflK could
G6M87_15470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_15480	COG2814	Major facilitator Superfamily
G6M87_15515	COG0482	sulfurtransferase activity
G6M87_15530	COG4589	Belongs to the CDS family
G6M87_15540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_15580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6M87_15585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6M87_15590	COG0037	tRNA processing
G6M87_15600	COG2885	chlorophyll binding
G6M87_15605	COG0823	Involved in the tonB-independent uptake of proteins
G6M87_15630	COG0824	Thioesterase
G6M87_15645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6M87_15650	COG1268	BioY protein
G6M87_15655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G6M87_15660	COG2318	DinB family
G6M87_15665	COG0494	nUDIX hydrolase
G6M87_15670	COG1408	metallophosphoesterase
G6M87_15675	COG2255	four-way junction helicase activity
G6M87_15680	COG0632	four-way junction helicase activity
G6M87_15695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G6M87_15700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_15705	COG0217	transcriptional regulatory protein
G6M87_15715	COG1692	metallophosphoesterase
G6M87_15725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6M87_15750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6M87_15765	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_15815	COG0126	phosphoglycerate kinase activity
G6M87_15820	COG3588	fructose-bisphosphate aldolase
G6M87_15825	COG0384	phenazine biosynthesis protein PhzF
G6M87_15855	COG0254	rRNA binding
G6M87_15865	COG3422	double-strand break repair
G6M87_15890	COG0483	inositol monophosphate 1-phosphatase activity
G6M87_15920	COG0640	Transcriptional regulator
G6M87_15935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G6M87_15940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6M87_15945	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G6M87_15950	COG0457	Tetratricopeptide repeat
G6M87_15955	COG0596	Alpha beta hydrolase
G6M87_15960	COG0583	DNA-binding transcription factor activity
G6M87_15990	COG0469	pyruvate kinase activity
G6M87_16010	COG3750	Belongs to the UPF0335 family
G6M87_16040	COG2372	response to copper ion
G6M87_16045	COG0726	polysaccharide deacetylase
G6M87_16065	COG3108	Peptidase M15
G6M87_16080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6M87_16080	COG0512	Glutamine amidotransferase of anthranilate synthase
G6M87_16100	COG5310	Homospermidine synthase
G6M87_16115	COG0737	Belongs to the 5'-nucleotidase family
G6M87_16120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G6M87_16125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6M87_16130	COG0330	HflC and HflK could
G6M87_16140	COG0517	IMP dehydrogenase activity
G6M87_16140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G6M87_16150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6M87_16155	COG2951	lytic endotransglycosylase activity
G6M87_16175	COG0069	glutamate synthase activity
G6M87_16175	COG0067	glutamate synthase
G6M87_16175	COG0070	glutamate synthase
G6M87_16195	COG0071	Belongs to the small heat shock protein (HSP20) family
G6M87_16205	COG1522	sequence-specific DNA binding
G6M87_16210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6M87_16265	COG0662	Cupin 2, conserved barrel domain protein
G6M87_16265	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
G6M87_16275	COG2307	Protein conserved in bacteria
G6M87_16275	COG2308	Evidence 4 Homologs of previously reported genes of
G6M87_16290	COG0058	SHG alpha-glucan phosphorylase activity
G6M87_16295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G6M87_16300	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G6M87_16305	COG0297	glycogen (starch) synthase activity
G6M87_16310	COG0033	Phosphoglucomutase
G6M87_16315	COG1523	belongs to the glycosyl hydrolase 13 family
G6M87_16330	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6M87_16330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6M87_16345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_16355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G6M87_16365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_16370	COG3920	Histidine kinase
G6M87_16370	COG2202	Pas domain
G6M87_16395	COG5001	Diguanylate cyclase
G6M87_16400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
G6M87_16405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6M87_16410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6M87_16415	COG1609	Transcriptional regulator
G6M87_16420	COG1846	Transcriptional regulator
G6M87_16430	COG0523	cobalamin synthesis protein
G6M87_16440	COG1045	serine acetyltransferase
G6M87_16465	COG0583	DNA-binding transcription factor activity
G6M87_16475	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
G6M87_16490	COG0800	Aldolase
G6M87_16495	COG2954	triphosphatase activity
G6M87_16505	COG2814	Major facilitator Superfamily
G6M87_16510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_16515	COG1609	Transcriptional regulator
G6M87_16520	COG1054	Belongs to the UPF0176 family
G6M87_16530	COG0431	NADPH-dependent FMN reductase
G6M87_16545	COG0673	inositol 2-dehydrogenase activity
G6M87_16555	COG1879	ABC-type sugar transport system periplasmic component
G6M87_16560	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_16570	COG1609	Transcriptional regulator
G6M87_16580	COG2115	Belongs to the xylose isomerase family
G6M87_16585	COG1070	Carbohydrate kinase
G6M87_16590	COG1609	Transcriptional regulator
G6M87_16615	COG1253	flavin adenine dinucleotide binding
G6M87_16625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6M87_16630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G6M87_16635	COG0673	inositol 2-dehydrogenase activity
G6M87_16640	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_16645	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_16665	COG0583	DNA-binding transcription factor activity
G6M87_16670	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G6M87_16675	COG3842	ATPase activity
G6M87_16680	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_16685	COG1177	transmembrane transport
G6M87_16705	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_16725	COG3254	rhamnose metabolic process
G6M87_16730	COG4948	Mandelate Racemase Muconate Lactonizing
G6M87_16735	COG3842	ATPase activity
G6M87_16740	COG0395	ABC-type sugar transport system, permease component
G6M87_16745	COG1175	transmembrane transport
G6M87_16775	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6M87_16795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6M87_16825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6M87_16840	COG0395	ABC-type sugar transport system, permease component
G6M87_16845	COG1175	transmembrane transport
G6M87_16855	COG2390	Transcriptional regulator
G6M87_16875	COG1940	carbohydrate kinase activity
G6M87_16880	COG3142	Participates in the control of copper homeostasis
G6M87_16895	COG2719	SpoVR family
G6M87_16900	COG2718	Belongs to the UPF0229 family
G6M87_16905	COG2766	serine protein kinase
G6M87_16920	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G6M87_16925	COG0424	maF-like protein
G6M87_16930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G6M87_16940	COG5328	Belongs to the UPF0262 family
G6M87_16945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G6M87_16955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6M87_16980	COG2514	catechol 2,3-dioxygenase activity
G6M87_16985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G6M87_16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_17015	COG1764	response to oxidative stress
G6M87_17020	COG2186	Transcriptional regulator
G6M87_17025	COG4948	Mandelate Racemase Muconate Lactonizing
G6M87_17030	COG0670	Belongs to the BI1 family
G6M87_17045	COG3781	membrane
G6M87_17050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G6M87_17055	COG2900	Belongs to the SlyX family
G6M87_17065	COG3842	ATPase activity
G6M87_17070	COG1175	transmembrane transport
G6M87_17085	COG1609	Transcriptional regulator
G6M87_17155	COG1396	sequence-specific DNA binding
G6M87_17195	COG0326	Molecular chaperone. Has ATPase activity
G6M87_17205	COG0326	Molecular chaperone. Has ATPase activity
G6M87_17215	COG2963	transposase activity
G6M87_17220	COG3436	PFAM IS66 Orf2 family protein
G6M87_17225	COG4372	Transposase
G6M87_17235	COG0477	Major facilitator Superfamily
G6M87_17285	COG0542	response to heat
G6M87_17295	COG2890	protein-(glutamine-N5) methyltransferase activity
G6M87_17300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G6M87_17310	COG0527	aspartate kinase activity
G6M87_17315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6M87_17330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6M87_17345	COG2226	methyltransferase
G6M87_17360	COG0494	nUDIX hydrolase
G6M87_17370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6M87_17375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6M87_17380	COG0653	protein targeting
G6M87_17385	COG0583	DNA-binding transcription factor activity
G6M87_17390	COG1942	4-Oxalocrotonate Tautomerase
G6M87_17395	COG0625	glutathione transferase activity
G6M87_17410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6M87_17425	COG0681	Belongs to the peptidase S26 family
G6M87_17430	COG0667	Aldo Keto reductase
G6M87_17435	COG2264	protein methyltransferase activity
G6M87_17490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6M87_17495	COG1295	ribonuclease BN
G6M87_17500	COG0300	oxidoreductase activity
G6M87_17515	COG2086	electron transfer activity
G6M87_17525	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6M87_17530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G6M87_17535	COG0165	Argininosuccinate lyase
G6M87_17570	COG2884	Cell division ATP-binding protein ftsE
G6M87_17590	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
G6M87_17610	COG0287	Prephenate dehydrogenase
G6M87_17615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G6M87_17620	COG2226	methyltransferase
G6M87_17625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6M87_17635	COG2382	esterase
G6M87_17650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G6M87_17685	COG4536	flavin adenine dinucleotide binding
G6M87_17690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G6M87_17695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G6M87_17705	COG4974	Belongs to the 'phage' integrase family
G6M87_17710	COG0825	malonyl-CoA metabolic process
G6M87_17715	COG3034	peptidoglycan biosynthetic process
G6M87_17725	COG0523	cobalamin synthesis protein
G6M87_17730	COG1686	Belongs to the peptidase S11 family
G6M87_17735	COG1473	amidohydrolase
G6M87_17765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G6M87_17775	COG0156	8-amino-7-oxononanoate synthase activity
G6M87_17800	COG0729	surface antigen
G6M87_17825	COG0010	Belongs to the arginase family
G6M87_17830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6M87_17835	COG0835	chemotaxis
G6M87_17840	COG2223	nitrite transmembrane transporter activity
G6M87_17850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G6M87_17855	COG3383	formate dehydrogenase (NAD+) activity
G6M87_17880	COG0640	Transcriptional regulator
G6M87_17885	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_17915	COG4948	Mandelate Racemase Muconate Lactonizing
G6M87_17920	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_17925	COG1454	alcohol dehydrogenase
G6M87_17935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G6M87_17940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G6M87_17945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G6M87_17950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G6M87_17955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G6M87_17990	COG4974	Belongs to the 'phage' integrase family
G6M87_18005	COG0612	Peptidase, M16
G6M87_18015	COG1280	lysine exporter protein (LysE YggA)
G6M87_18020	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_18035	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6M87_18050	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G6M87_18055	COG0045	succinate-CoA ligase (ADP-forming) activity
G6M87_18060	COG0039	L-malate dehydrogenase activity
G6M87_18065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G6M87_18110	COG2350	Protein conserved in bacteria
G6M87_18115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G6M87_18120	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G6M87_18125	COG0181	hydroxymethylbilane synthase activity
G6M87_18170	COG1872	DUF167
G6M87_18175	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G6M87_18185	COG1217	gtp-binding protein TYPA
G6M87_18190	COG0339	signal peptide processing
G6M87_18205	COG0137	argininosuccinate synthase activity
G6M87_18215	COG1280	lysine exporter protein (LysE YggA)
G6M87_18225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G6M87_18240	COG2154	pterin-4-alpha-carbinolamine dehydratase
G6M87_18245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6M87_18250	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
G6M87_18260	COG4181	ATPase activity
G6M87_18270	COG0670	Belongs to the BI1 family
G6M87_18295	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6M87_18300	COG4133	protoheme IX ABC transporter activity
G6M87_18305	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6M87_18310	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G6M87_18330	COG2917	probably involved in intracellular septation
G6M87_18335	COG0552	protein localization to endoplasmic reticulum
G6M87_18340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G6M87_18345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G6M87_18365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6M87_18370	COG0287	Prephenate dehydrogenase
G6M87_18370	COG1605	Chorismate mutase
G6M87_18375	COG0228	four-way junction DNA binding
G6M87_18380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6M87_18385	COG0336	Belongs to the RNA methyltransferase TrmD family
G6M87_18420	COG1522	sequence-specific DNA binding
G6M87_18430	COG0110	maltose O-acetyltransferase activity
G6M87_18435	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G6M87_18440	COG0335	large ribosomal subunit rRNA binding
G6M87_18450	COG0765	amino acid transport
G6M87_18455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G6M87_18460	COG0697	spore germination
G6M87_18465	COG1846	Transcriptional regulator
G6M87_18485	COG0656	L-ascorbic acid biosynthetic process
G6M87_18495	COG0745	RESPONSE REGULATOR receiver
G6M87_18510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G6M87_18515	COG1674	ftsk spoiiie
G6M87_18520	COG0004	ammonium transporteR
G6M87_18525	COG0347	Belongs to the P(II) protein family
G6M87_18530	COG1946	Acyl-CoA thioesterase
G6M87_18535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6M87_18540	COG1733	regulation of RNA biosynthetic process
G6M87_18550	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_18555	COG2835	tetraacyldisaccharide 4'-kinase activity
G6M87_18565	COG3118	belongs to the thioredoxin family
G6M87_18590	COG0395	ABC-type sugar transport system, permease component
G6M87_18595	COG1175	transmembrane transport
G6M87_18605	COG3250	beta-galactosidase activity
G6M87_18610	COG1609	Transcriptional regulator
G6M87_18630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_18640	COG0745	RESPONSE REGULATOR receiver
G6M87_18645	COG2205	protein histidine kinase activity
G6M87_18700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6M87_18705	COG2076	Multidrug Resistance protein
G6M87_18715	COG1647	Serine aminopeptidase, S33
G6M87_18725	COG2076	Multidrug Resistance protein
G6M87_18735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6M87_18740	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
G6M87_18755	COG3618	amidohydrolase
G6M87_18760	COG2814	Major facilitator Superfamily
G6M87_18765	COG2188	Transcriptional regulator
G6M87_18770	COG0583	DNA-binding transcription factor activity
G6M87_18780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6M87_18785	COG0697	spore germination
G6M87_18795	COG1309	transcriptional regulator
G6M87_18815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
G6M87_18830	COG0438	transferase activity, transferring glycosyl groups
G6M87_18865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_18870	COG1116	anion transmembrane transporter activity
G6M87_18875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_18885	COG1396	sequence-specific DNA binding
G6M87_18920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_18925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6M87_18935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6M87_18985	COG2814	Major facilitator Superfamily
G6M87_18990	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G6M87_19005	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G6M87_19010	COG2986	histidine ammonia-lyase
G6M87_19015	COG1228	amidohydrolase
G6M87_19020	COG0402	S-adenosylhomocysteine deaminase activity
G6M87_19025	COG2188	Transcriptional regulator
G6M87_19035	COG2986	histidine ammonia-lyase
G6M87_19055	COG0025	NhaP-type Na H and K H
G6M87_19085	COG1321	iron dependent repressor
G6M87_19090	COG1914	H( )-stimulated, divalent metal cation uptake system
G6M87_19095	COG0739	heme binding
G6M87_19110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6M87_19115	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G6M87_19120	COG2080	2 iron, 2 sulfur cluster binding
G6M87_19125	COG1309	transcriptional regulator
G6M87_19135	COG3842	ATPase activity
G6M87_19140	COG0395	ABC-type sugar transport system, permease component
G6M87_19145	COG1175	transmembrane transport
G6M87_19185	COG3842	ATPase activity
G6M87_19195	COG0395	ABC-type sugar transport system, permease component
G6M87_19210	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
G6M87_19215	COG2182	Extracellular solute-binding protein
G6M87_19230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_19240	COG0673	inositol 2-dehydrogenase activity
G6M87_19250	COG0673	inositol 2-dehydrogenase activity
G6M87_19255	COG1309	transcriptional regulator
G6M87_19265	COG1175	transmembrane transport
G6M87_19270	COG0395	ABC-type sugar transport system, permease component
G6M87_19275	COG0673	inositol 2-dehydrogenase activity
G6M87_19280	COG0673	inositol 2-dehydrogenase activity
G6M87_19300	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G6M87_19310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6M87_19315	COG1509	lysine 2,3-aminomutase activity
G6M87_19320	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G6M87_19325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G6M87_19345	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G6M87_19370	COG2188	Transcriptional regulator
G6M87_19375	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6M87_19380	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G6M87_19395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_19400	COG0488	(ABC) transporter
G6M87_19415	COG2814	Major facilitator Superfamily
G6M87_19430	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G6M87_19445	COG1329	Transcriptional regulator
G6M87_19450	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6M87_19485	COG0183	Belongs to the thiolase family
G6M87_19490	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
G6M87_19495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G6M87_19505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6M87_19510	COG0142	geranyltranstransferase activity
G6M87_19520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G6M87_19525	COG2223	nitrite transmembrane transporter activity
G6M87_19530	COG0697	spore germination
G6M87_19555	COG0662	Cupin 2, conserved barrel domain protein
G6M87_19570	COG0740	serine-type endopeptidase activity
G6M87_19575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_19580	COG0765	amino acid transport
G6M87_19585	COG1126	abc transporter atp-binding protein
G6M87_19595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_19600	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
G6M87_19610	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
G6M87_19620	COG1132	(ABC) transporter
G6M87_19635	COG3459	Glycosyltransferase 36 associated
G6M87_19660	COG0444	Belongs to the ABC transporter superfamily
G6M87_19665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_19670	COG0601	transmembrane transport
G6M87_19685	COG1280	lysine exporter protein (LysE YggA)
G6M87_19690	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
G6M87_19690	COG4447	cellulose binding
G6M87_19760	COG4211	Belongs to the binding-protein-dependent transport system permease family
G6M87_19765	COG1129	ABC transporter
G6M87_19780	COG0673	inositol 2-dehydrogenase activity
G6M87_19785	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_19810	COG2130	NADP-dependent
G6M87_19860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_19870	COG3938	Belongs to the proline racemase family
G6M87_19875	COG4176	ABC-type proline glycine betaine transport system permease component
G6M87_19880	COG4176	ABC-type proline glycine betaine transport system permease component
G6M87_19885	COG3448	diguanylate cyclase activity
G6M87_19885	COG4175	Glycine betaine
G6M87_19900	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_19905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_19910	COG1802	Transcriptional regulator
G6M87_19930	COG0840	transmembrane signaling receptor activity
G6M87_19935	COG0395	ABC-type sugar transport system, permease component
G6M87_19940	COG1175	transmembrane transport
G6M87_19945	COG1653	transport
G6M87_19950	COG3842	ATPase activity
G6M87_19955	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_19960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6M87_19965	COG2186	Transcriptional regulator
G6M87_19985	COG1116	anion transmembrane transporter activity
G6M87_19990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_20005	COG0640	Transcriptional regulator
G6M87_20050	COG0436	Aminotransferase
G6M87_20065	COG1079	Belongs to the binding-protein-dependent transport system permease family
G6M87_20110	COG0659	secondary active sulfate transmembrane transporter activity
G6M87_20120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_20125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_20150	COG0438	transferase activity, transferring glycosyl groups
G6M87_20155	COG2144	transferase activity, transferring acyl groups
G6M87_20180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6M87_20215	COG1175	transmembrane transport
G6M87_20220	COG0395	ABC-type sugar transport system, permease component
G6M87_20225	COG3842	ATPase activity
G6M87_20245	COG4774	siderophore transport
G6M87_20265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G6M87_20270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6M87_20275	COG2186	Transcriptional regulator
G6M87_20280	COG0747	negative chemotaxis
G6M87_20285	COG0601	transmembrane transport
G6M87_20290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_20300	COG0402	S-adenosylhomocysteine deaminase activity
G6M87_20310	COG4608	Belongs to the ABC transporter superfamily
G6M87_20320	COG0583	DNA-binding transcription factor activity
G6M87_20325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G6M87_20335	COG1129	ABC transporter
G6M87_20345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G6M87_20355	COG0747	negative chemotaxis
G6M87_20360	COG0601	transmembrane transport
G6M87_20365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_20370	COG4172	Belongs to the ABC transporter superfamily
G6M87_20380	COG0477	Major facilitator Superfamily
G6M87_20385	COG0583	DNA-binding transcription factor activity
G6M87_20390	COG0583	DNA-binding transcription factor activity
G6M87_20395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6M87_20405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G6M87_20405	COG4797	methyltransferase
G6M87_20420	COG4957	zinc ion binding
G6M87_20450	COG2204	response regulator
G6M87_20460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6M87_20465	COG3932	Exopolysaccharide synthesis, ExoD
G6M87_20485	COG0765	amino acid transport
G6M87_20505	COG0006	proline dipeptidase activity
G6M87_20520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_20525	COG1802	Transcriptional regulator
G6M87_20530	COG1984	allophanate hydrolase subunit 2
G6M87_20535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_20540	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_20555	COG0765	amino acid transport
G6M87_20560	COG0765	amino acid transport
G6M87_20570	COG0010	Belongs to the arginase family
G6M87_20590	COG2072	flavoprotein involved in K transport
G6M87_20595	COG1126	abc transporter atp-binding protein
G6M87_20600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_20605	COG0765	amino acid transport
G6M87_20610	COG0765	amino acid transport
G6M87_20620	COG1921	L-seryl-tRNASec selenium transferase activity
G6M87_20635	COG3964	amidohydrolase
G6M87_20645	COG0601	transmembrane transport
G6M87_20650	COG0747	negative chemotaxis
G6M87_20675	COG0028	Belongs to the TPP enzyme family
G6M87_20680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6M87_20695	COG4166	transmembrane transport
G6M87_20730	COG1609	Transcriptional regulator
G6M87_20735	COG1840	ABC-type Fe3 transport system, periplasmic component
G6M87_20745	COG3842	ATPase activity
G6M87_20775	COG1215	transferase activity, transferring glycosyl groups
G6M87_20785	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
G6M87_20795	COG5001	Diguanylate cyclase
G6M87_20795	COG4251	negative regulation of phosphorylation
G6M87_20795	COG3706	GGDEF domain
G6M87_20795	COG2203	Gaf domain
G6M87_20800	COG1609	Transcriptional regulator
G6M87_20810	COG1129	ABC transporter
G6M87_20815	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_20875	COG1459	type II secretion system
G6M87_20880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G6M87_20905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_20920	COG1376	ErfK ybiS ycfS ynhG family protein
G6M87_20935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_20940	COG1473	amidohydrolase
G6M87_20960	COG0436	Aminotransferase
G6M87_20970	COG4302	ethanolamine ammonia-lyase activity
G6M87_20975	COG4303	Ethanolamine ammonia lyase large subunit
G6M87_20995	COG0235	Class ii aldolase
G6M87_21005	COG3239	Fatty acid desaturase
G6M87_21020	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G6M87_21030	COG3665	Urea carboxylase-associated protein
G6M87_21035	COG4770	biotin carboxylase activity
G6M87_21045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6M87_21075	COG0596	Alpha beta hydrolase
G6M87_21080	COG1192	Involved in chromosome partitioning
G6M87_21085	COG1475	DNA binding
G6M87_21090	COG0640	Transcriptional regulator
G6M87_21105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_21115	COG0583	DNA-binding transcription factor activity
G6M87_21165	COG0745	RESPONSE REGULATOR receiver
G6M87_21175	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_21180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_21195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_21245	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_21255	COG0840	transmembrane signaling receptor activity
G6M87_21270	COG1902	pentaerythritol trinitrate reductase activity
G6M87_21275	COG0427	acetyl-CoA hydrolase
G6M87_21280	COG3547	Transposase (IS116 IS110 IS902 family)
G6M87_21290	COG4208	sulfate ABC transporter
G6M87_21295	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_21305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_21315	COG3842	ATPase activity
G6M87_21320	COG0583	DNA-binding transcription factor activity
G6M87_21325	COG1126	abc transporter atp-binding protein
G6M87_21330	COG0765	amino acid transport
G6M87_21335	COG0765	amino acid transport
G6M87_21350	COG0667	Aldo Keto reductase
G6M87_21355	COG0583	DNA-binding transcription factor activity
G6M87_21365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6M87_21370	COG2267	carboxylic ester hydrolase activity
G6M87_21375	COG0251	oxidation-reduction process
G6M87_21380	COG1335	isochorismatase
G6M87_21385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_21390	COG5265	(ABC) transporter
G6M87_21405	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_21410	COG1940	carbohydrate kinase activity
G6M87_21410	COG1846	Transcriptional regulator
G6M87_21415	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_21420	COG2207	Transcriptional regulator
G6M87_21420	COG1917	Cupin 2, conserved barrel domain protein
G6M87_21430	COG1175	transmembrane transport
G6M87_21445	COG1063	alcohol dehydrogenase
G6M87_21450	COG3842	ATPase activity
G6M87_21455	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_21480	COG0006	proline dipeptidase activity
G6M87_21485	COG4948	Mandelate Racemase Muconate Lactonizing
G6M87_21490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_21495	COG1126	abc transporter atp-binding protein
G6M87_21500	COG0765	amino acid transport
G6M87_21505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_21510	COG2186	Transcriptional regulator
G6M87_21515	COG1177	transmembrane transport
G6M87_21520	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_21525	COG3842	ATPase activity
G6M87_21535	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
G6M87_21540	COG1024	Enoyl-CoA hydratase
G6M87_21550	COG0277	FAD linked oxidase domain protein
G6M87_21560	COG0604	alcohol dehydrogenase
G6M87_21565	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
G6M87_21570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_21595	COG1802	Transcriptional regulator
G6M87_21600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_21605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_21625	COG0765	amino acid transport
G6M87_21630	COG0765	amino acid transport
G6M87_21635	COG1126	abc transporter atp-binding protein
G6M87_21650	COG0444	Belongs to the ABC transporter superfamily
G6M87_21655	COG4608	Belongs to the ABC transporter superfamily
G6M87_21660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_21670	COG0747	negative chemotaxis
G6M87_21675	COG3257	ureidoglycine aminohydrolase activity
G6M87_21685	COG4993	Dehydrogenase
G6M87_21715	COG0840	transmembrane signaling receptor activity
G6M87_21720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6M87_21740	COG3485	protocatechuate 3,4-dioxygenase
G6M87_21755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6M87_21765	COG2814	Major facilitator Superfamily
G6M87_21790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_21865	COG2084	Dehydrogenase
G6M87_21870	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_21875	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_21885	COG1129	ABC transporter
G6M87_21940	COG0235	Class ii aldolase
G6M87_21950	COG2423	ornithine cyclodeaminase activity
G6M87_21960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6M87_21965	COG0477	Major facilitator Superfamily
G6M87_21975	COG0583	DNA-binding transcription factor activity
G6M87_21980	COG1309	transcriptional regulator
G6M87_21985	COG2814	Major facilitator Superfamily
G6M87_21990	COG0583	DNA-binding transcription factor activity
G6M87_22005	COG0583	DNA-binding transcription factor activity
G6M87_22030	COG1335	isochorismatase
G6M87_22040	COG1802	Transcriptional regulator
G6M87_22045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6M87_22050	COG4569	acetaldehyde dehydrogenase (acetylating) activity
G6M87_22055	COG3193	protein, possibly involved in utilization of glycolate and propanediol
G6M87_22070	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6M87_22085	COG3971	2-oxopent-4-enoate hydratase activity
G6M87_22145	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_22150	COG0583	DNA-binding transcription factor activity
G6M87_22155	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_22165	COG1335	isochorismatase
G6M87_22170	COG0583	DNA-binding transcription factor activity
G6M87_22175	COG0583	DNA-binding transcription factor activity
G6M87_22195	COG0697	spore germination
G6M87_22210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_22215	COG0683	leucine binding
G6M87_22230	COG0411	ABC transporter
G6M87_22245	COG1802	Transcriptional regulator
G6M87_22265	COG0765	amino acid transport
G6M87_22270	COG0765	amino acid transport
G6M87_22280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_22290	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_22295	COG2197	response regulator
G6M87_22300	COG0601	transmembrane transport
G6M87_22305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_22325	COG0747	negative chemotaxis
G6M87_22345	COG4191	Histidine kinase
G6M87_22345	COG0784	Response regulator, receiver
G6M87_22350	COG2197	response regulator
G6M87_22365	COG3920	Histidine kinase
G6M87_22380	COG1079	Belongs to the binding-protein-dependent transport system permease family
G6M87_22385	COG4603	Belongs to the binding-protein-dependent transport system permease family
G6M87_22390	COG3845	ABC transporter
G6M87_22405	COG0793	Belongs to the peptidase S41A family
G6M87_22410	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_22420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6M87_22430	COG1177	transmembrane transport
G6M87_22435	COG3842	ATPase activity
G6M87_22445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_22450	COG0583	DNA-binding transcription factor activity
G6M87_22500	COG0583	DNA-binding transcription factor activity
G6M87_22510	COG0583	DNA-binding transcription factor activity
G6M87_22515	COG3384	dioxygenase
G6M87_22535	COG0025	NhaP-type Na H and K H
G6M87_22550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_22555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6M87_22575	COG2022	thiamine diphosphate biosynthetic process
G6M87_22590	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G6M87_22595	COG1609	Transcriptional regulator
G6M87_22605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_22610	COG0765	amino acid transport
G6M87_22615	COG0765	amino acid transport
G6M87_22625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6M87_22635	COG0583	DNA-binding transcription factor activity
G6M87_22650	COG0765	amino acid transport
G6M87_22655	COG1126	abc transporter atp-binding protein
G6M87_22660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_22665	COG1522	sequence-specific DNA binding
G6M87_22680	COG0667	Aldo Keto reductase
G6M87_22685	COG2814	Major facilitator Superfamily
G6M87_22695	COG0583	DNA-binding transcription factor activity
G6M87_22705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6M87_22710	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
G6M87_22715	COG2080	2 iron, 2 sulfur cluster binding
G6M87_22755	COG3153	acetyltransferase
G6M87_22780	COG0698	ribose 5-phosphate isomerase
G6M87_22785	COG0149	triose-phosphate isomerase activity
G6M87_22820	COG1129	ABC transporter
G6M87_22825	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_22830	COG1879	ABC-type sugar transport system periplasmic component
G6M87_22835	COG1349	DNA-binding transcription factor activity
G6M87_22845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G6M87_22855	COG0511	ligase activity, forming carbon-carbon bonds
G6M87_22860	COG0439	Biotin carboxylase
G6M87_22870	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_22875	COG1984	allophanate hydrolase subunit 2
G6M87_22880	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_22885	COG0436	Aminotransferase
G6M87_22895	COG4221	oxidoreductase activity
G6M87_22900	COG0765	amino acid transport
G6M87_22905	COG0765	amino acid transport
G6M87_22920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6M87_22930	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_22950	COG1984	allophanate hydrolase subunit 2
G6M87_22960	COG3842	ATPase activity
G6M87_22965	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_22980	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_22990	COG3842	ATPase activity
G6M87_22995	COG0726	polysaccharide deacetylase
G6M87_23005	COG0523	cobalamin synthesis protein
G6M87_23020	COG2909	trisaccharide binding
G6M87_23035	COG3842	ATPase activity
G6M87_23045	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_23050	COG1177	transmembrane transport
G6M87_23055	COG1129	ABC transporter
G6M87_23060	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_23065	COG1879	ABC-type sugar transport system periplasmic component
G6M87_23070	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_23075	COG2376	Dihydroxyacetone kinase
G6M87_23085	COG2376	Dihydroxyacetone kinase
G6M87_23110	COG2207	Transcriptional regulator
G6M87_23115	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_23125	COG1335	isochorismatase
G6M87_23130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G6M87_23135	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_23215	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_23220	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
G6M87_23225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G6M87_23245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6M87_23250	COG4191	Histidine kinase
G6M87_23250	COG0784	Response regulator, receiver
G6M87_23260	COG1294	oxidase, subunit
G6M87_23265	COG1271	oxidase subunit
G6M87_23270	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G6M87_23275	COG4988	ABC transporter
G6M87_23285	COG0517	IMP dehydrogenase activity
G6M87_23285	COG0516	GMP reductase activity
G6M87_23315	COG4372	Transposase
G6M87_23325	COG2963	transposase activity
G6M87_23340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6M87_23345	COG3609	addiction module antidote protein, CC2985 family
G6M87_23350	COG3668	Plasmid stabilization system
G6M87_23390	COG2208	phosphoserine phosphatase activity
G6M87_23395	COG2226	methyltransferase
G6M87_23405	COG5001	Diguanylate cyclase
G6M87_23405	COG3300	MHYT domain
G6M87_23410	COG0745	RESPONSE REGULATOR receiver
G6M87_23410	COG2205	protein histidine kinase activity
G6M87_23410	COG3292	Two component regulator propeller
G6M87_23420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6M87_23430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G6M87_23470	COG2273	Hydrolase Family 16
G6M87_23470	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
G6M87_23495	COG2197	response regulator
G6M87_23500	COG2890	protein-(glutamine-N5) methyltransferase activity
G6M87_23505	COG0367	asparagine synthase
G6M87_23515	COG0318	PFAM AMP-dependent synthetase and ligase
G6M87_23520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6M87_23525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6M87_23525	COG3321	synthase
G6M87_23525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G6M87_23525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6M87_23535	COG3300	MHYT domain
G6M87_23535	COG5001	Diguanylate cyclase
G6M87_23545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G6M87_23575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_23580	COG1116	anion transmembrane transporter activity
G6M87_23585	COG4191	Histidine kinase
G6M87_23595	COG1609	Transcriptional regulator
G6M87_23600	COG2271	Major facilitator Superfamily
G6M87_23605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_23610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_23660	COG4774	siderophore transport
G6M87_23665	COG2814	Major facilitator Superfamily
G6M87_23680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_23685	COG0454	-acetyltransferase
G6M87_23690	COG0747	negative chemotaxis
G6M87_23695	COG0747	negative chemotaxis
G6M87_23715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_23770	COG1653	transport
G6M87_23775	COG2188	Transcriptional regulator
G6M87_23795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_23800	COG0601	transmembrane transport
G6M87_23805	COG0747	negative chemotaxis
G6M87_23810	COG2186	Transcriptional regulator
G6M87_23815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_23820	COG0747	negative chemotaxis
G6M87_23825	COG0601	transmembrane transport
G6M87_23830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_23835	COG0444	Belongs to the ABC transporter superfamily
G6M87_23840	COG4608	Belongs to the ABC transporter superfamily
G6M87_23845	COG3609	addiction module antidote protein, CC2985 family
G6M87_23855	COG0483	inositol monophosphate 1-phosphatase activity
G6M87_23860	COG0584	glycerophosphoryl diester phosphodiesterase
G6M87_23865	COG1940	carbohydrate kinase activity
G6M87_23870	COG3300	MHYT domain
G6M87_23870	COG5001	Diguanylate cyclase
G6M87_23890	COG3755	Protein conserved in bacteria
G6M87_23910	COG0840	transmembrane signaling receptor activity
G6M87_23915	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_23920	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_23925	COG1129	ABC transporter
G6M87_23940	COG0477	Major facilitator Superfamily
G6M87_23945	COG1309	transcriptional regulator
G6M87_23950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6M87_23960	COG3344	reverse transcriptase
G6M87_23980	COG1396	sequence-specific DNA binding
G6M87_23995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6M87_24010	COG0840	transmembrane signaling receptor activity
G6M87_24025	COG3177	Filamentation induced by cAMP protein fic
G6M87_24070	COG0596	Alpha beta hydrolase
G6M87_24125	COG2124	cytochrome p450
G6M87_24130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6M87_24130	COG3321	synthase
G6M87_24130	COG4221	oxidoreductase activity
G6M87_24130	COG0300	oxidoreductase activity
G6M87_24145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6M87_24175	COG0028	Belongs to the TPP enzyme family
G6M87_24175	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
G6M87_24180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G6M87_24210	COG4372	Transposase
G6M87_24220	COG2963	transposase activity
G6M87_24230	COG2072	flavoprotein involved in K transport
G6M87_24240	COG2963	transposase activity
G6M87_24250	COG4372	Transposase
G6M87_24265	COG2963	transposase activity
G6M87_24280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_24295	COG1131	(ABC) transporter
G6M87_24355	COG1278	Cold shock
G6M87_24360	COG2207	Transcriptional regulator
G6M87_24365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6M87_24385	COG0651	ATP synthesis coupled electron transport
G6M87_24390	COG0650	Formate hydrogenlyase subunit 4
G6M87_24400	COG0651	ATP synthesis coupled electron transport
G6M87_24405	COG0649	NAD binding
G6M87_24410	COG3260	NADH ubiquinone oxidoreductase 20
G6M87_24435	COG1278	Cold shock
G6M87_24450	COG2824	Alkylphosphonate utilization operon protein PhnA
G6M87_24455	COG0776	regulation of translation
G6M87_24495	COG1177	transmembrane transport
G6M87_24500	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_24505	COG3842	ATPase activity
G6M87_24515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_24520	COG0174	glutamine synthetase
G6M87_24525	COG1574	metal-dependent hydrolase with the TIM-barrel fold
G6M87_24530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_24535	COG0174	glutamine synthetase
G6M87_24620	COG0745	RESPONSE REGULATOR receiver
G6M87_24655	COG0642	Histidine kinase
G6M87_24675	COG0463	Glycosyl transferase, family 2
G6M87_24695	COG3038	cytochrome b561
G6M87_24705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6M87_24740	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6M87_24800	COG0444	Belongs to the ABC transporter superfamily
G6M87_24805	COG2186	Transcriptional regulator
G6M87_24810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_24815	COG0601	transmembrane transport
G6M87_24830	COG1937	Protein conserved in bacteria
G6M87_24870	COG1254	Belongs to the acylphosphatase family
G6M87_24885	COG1845	cytochrome c oxidase, subunit III
G6M87_24890	COG1845	cytochrome c oxidase, subunit III
G6M87_24895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6M87_24900	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6M87_24935	COG4221	oxidoreductase activity
G6M87_24940	COG1309	transcriptional regulator
G6M87_24945	COG0587	DNA-directed DNA polymerase activity
G6M87_24950	COG4974	Belongs to the 'phage' integrase family
G6M87_24955	COG0517	IMP dehydrogenase activity
G6M87_24970	COG2072	flavoprotein involved in K transport
G6M87_24990	COG1472	Belongs to the glycosyl hydrolase 3 family
G6M87_25005	COG0395	ABC-type sugar transport system, permease component
G6M87_25010	COG1175	transmembrane transport
G6M87_25015	COG1653	transport
G6M87_25035	COG0601	transmembrane transport
G6M87_25040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_25045	COG4608	Belongs to the ABC transporter superfamily
G6M87_25055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_25080	COG1609	Transcriptional regulator
G6M87_25125	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G6M87_25130	COG1126	abc transporter atp-binding protein
G6M87_25135	COG0765	amino acid transport
G6M87_25140	COG0765	amino acid transport
G6M87_25150	COG2188	Transcriptional regulator
G6M87_25170	COG1070	Carbohydrate kinase
G6M87_25185	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_25190	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_25195	COG1129	ABC transporter
G6M87_25200	COG1349	DNA-binding transcription factor activity
G6M87_25295	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_25310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_25315	COG0159	tryptophan synthase activity
G6M87_25325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_25330	COG3842	ATPase activity
G6M87_25335	COG3833	ABC-type maltose transport systems, permease component
G6M87_25340	COG1175	transmembrane transport
G6M87_25355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_25365	COG1595	DNA-templated transcription, initiation
G6M87_25400	COG0444	Belongs to the ABC transporter superfamily
G6M87_25405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_25420	COG0747	negative chemotaxis
G6M87_25425	COG2186	Transcriptional regulator
G6M87_25450	COG3842	ATPase activity
G6M87_25485	COG2272	Belongs to the type-B carboxylesterase lipase family
G6M87_25500	COG2211	Major facilitator Superfamily
G6M87_25520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G6M87_25530	COG1280	lysine exporter protein (LysE YggA)
G6M87_25535	COG2197	response regulator
G6M87_25545	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G6M87_25550	COG0720	synthase
G6M87_25555	COG0602	queuosine metabolic process
G6M87_25570	COG2267	carboxylic ester hydrolase activity
G6M87_25580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_25585	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_25605	COG1177	transmembrane transport
G6M87_25610	COG3842	ATPase activity
G6M87_25620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_25635	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_25645	COG0410	ABC transporter
G6M87_25655	COG2706	6-phosphogluconolactonase activity
G6M87_25660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_25665	COG1312	Catalyzes the dehydration of D-mannonate
G6M87_25670	COG2186	Transcriptional regulator
G6M87_25680	COG0601	transmembrane transport
G6M87_25685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_25740	COG4774	siderophore transport
G6M87_25755	COG1473	amidohydrolase
G6M87_25760	COG0747	negative chemotaxis
G6M87_25765	COG0601	transmembrane transport
G6M87_25770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_25775	COG4172	Belongs to the ABC transporter superfamily
G6M87_25785	COG3386	PFAM SMP-30 Gluconolaconase
G6M87_25795	COG1063	alcohol dehydrogenase
G6M87_25800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G6M87_25805	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_25810	COG2084	Dehydrogenase
G6M87_25820	COG1609	Transcriptional regulator
G6M87_25830	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_25835	COG1129	ABC transporter
G6M87_25845	COG0840	transmembrane signaling receptor activity
G6M87_25865	COG4214	carbohydrate transport
G6M87_25875	COG1070	Carbohydrate kinase
G6M87_25880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_25885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_25890	COG0601	transmembrane transport
G6M87_25915	COG4172	Belongs to the ABC transporter superfamily
G6M87_25920	COG3842	ATPase activity
G6M87_25930	COG0516	GMP reductase activity
G6M87_25945	COG0673	inositol 2-dehydrogenase activity
G6M87_25955	COG0395	ABC-type sugar transport system, permease component
G6M87_25970	COG0673	inositol 2-dehydrogenase activity
G6M87_25985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_25990	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
G6M87_25995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6M87_26000	COG2390	Transcriptional regulator
G6M87_26010	COG1940	carbohydrate kinase activity
G6M87_26015	COG1879	ABC-type sugar transport system periplasmic component
G6M87_26045	COG0765	amino acid transport
G6M87_26050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_26060	COG1126	abc transporter atp-binding protein
G6M87_26080	COG1522	sequence-specific DNA binding
G6M87_26135	COG0864	Transcriptional regulator
G6M87_26145	COG1609	Transcriptional regulator
G6M87_26170	COG0697	spore germination
G6M87_26175	COG0489	protein tyrosine kinase activity
G6M87_26175	COG3206	protein involved in exopolysaccharide biosynthesis
G6M87_26180	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6M87_26185	COG1215	transferase activity, transferring glycosyl groups
G6M87_26190	COG1215	transferase activity, transferring glycosyl groups
G6M87_26195	COG1215	transferase activity, transferring glycosyl groups
G6M87_26200	COG0438	transferase activity, transferring glycosyl groups
G6M87_26205	COG2273	Hydrolase Family 16
G6M87_26210	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6M87_26220	COG2244	polysaccharide biosynthetic process
G6M87_26225	COG0463	Glycosyl transferase, family 2
G6M87_26230	COG2327	Polysaccharide pyruvyl transferase
G6M87_26235	COG1215	transferase activity, transferring glycosyl groups
G6M87_26250	COG1596	polysaccharide export
G6M87_26255	COG3307	-O-antigen
G6M87_26260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6M87_26270	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_26290	COG2721	sulfolactate sulfo-lyase activity
G6M87_26305	COG2207	Transcriptional regulator
G6M87_26310	COG1486	melibiose metabolic process
G6M87_26315	COG0747	negative chemotaxis
G6M87_26320	COG0601	transmembrane transport
G6M87_26325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_26330	COG4172	Belongs to the ABC transporter superfamily
G6M87_26335	COG1486	melibiose metabolic process
G6M87_26355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6M87_26355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G6M87_26360	COG1132	(ABC) transporter
G6M87_26380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_26390	COG0747	negative chemotaxis
G6M87_26420	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
G6M87_26435	COG1234	tRNA 3'-trailer cleavage
G6M87_26460	COG0559	Belongs to the binding-protein-dependent transport system permease family
G6M87_26470	COG0683	leucine binding
G6M87_26480	COG3485	protocatechuate 3,4-dioxygenase
G6M87_26485	COG3485	protocatechuate 3,4-dioxygenase
G6M87_26490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6M87_26495	COG2267	carboxylic ester hydrolase activity
G6M87_26500	COG0583	DNA-binding transcription factor activity
G6M87_26515	COG1414	Transcriptional regulator
G6M87_26525	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6M87_26535	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_26570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6M87_26585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6M87_26590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G6M87_26595	COG4208	sulfate ABC transporter
G6M87_26605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6M87_26610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6M87_26620	COG2205	protein histidine kinase activity
G6M87_26625	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
G6M87_26630	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6M87_26635	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G6M87_26670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_26675	COG0444	Belongs to the ABC transporter superfamily
G6M87_26680	COG4608	Belongs to the ABC transporter superfamily
G6M87_26695	COG2197	response regulator
G6M87_26700	COG0784	Response regulator, receiver
G6M87_26700	COG2205	protein histidine kinase activity
G6M87_26715	COG0235	Class ii aldolase
G6M87_26720	COG3395	kinase activity
G6M87_26725	COG3622	Belongs to the hyi family
G6M87_26730	COG2084	Dehydrogenase
G6M87_26735	COG2271	Major facilitator Superfamily
G6M87_26740	COG1609	Transcriptional regulator
G6M87_26750	COG0765	amino acid transport
G6M87_26755	COG0765	amino acid transport
G6M87_26765	COG0251	oxidation-reduction process
G6M87_26780	COG0235	Class ii aldolase
G6M87_26790	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_26795	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_26800	COG1129	ABC transporter
G6M87_26810	COG1609	Transcriptional regulator
G6M87_26830	COG1215	transferase activity, transferring glycosyl groups
G6M87_26870	COG1278	Cold shock
G6M87_26885	COG0659	secondary active sulfate transmembrane transporter activity
G6M87_26915	COG2205	protein histidine kinase activity
G6M87_26920	COG1396	sequence-specific DNA binding
G6M87_26955	COG1596	polysaccharide export
G6M87_26960	COG0438	transferase activity, transferring glycosyl groups
G6M87_26995	COG1215	transferase activity, transferring glycosyl groups
G6M87_27035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G6M87_27060	COG0583	DNA-binding transcription factor activity
G6M87_27065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_27070	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_27075	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_27110	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_27120	COG1473	amidohydrolase
G6M87_27135	COG0601	transmembrane transport
G6M87_27150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6M87_27165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6M87_27175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_27180	COG0601	transmembrane transport
G6M87_27185	COG0747	negative chemotaxis
G6M87_27190	COG0306	phosphate transporter
G6M87_27195	COG1392	Phosphate transport regulator
G6M87_27200	COG3842	ATPase activity
G6M87_27205	COG0395	ABC-type sugar transport system, permease component
G6M87_27210	COG1175	transmembrane transport
G6M87_27215	COG1653	transport
G6M87_27220	COG0697	spore germination
G6M87_27245	COG0747	negative chemotaxis
G6M87_27255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_27265	COG1733	regulation of RNA biosynthetic process
G6M87_27275	COG1132	(ABC) transporter
G6M87_27280	COG0463	Glycosyl transferase, family 2
G6M87_27285	COG1216	Glycosyl transferase, family 2
G6M87_27290	COG2755	lipolytic protein G-D-S-L family
G6M87_27290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G6M87_27300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_27305	COG2079	MmgE PrpD family protein
G6M87_27310	COG1126	abc transporter atp-binding protein
G6M87_27315	COG0765	amino acid transport
G6M87_27340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6M87_27345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6M87_27350	COG1120	ATPase activity
G6M87_27360	COG5001	Diguanylate cyclase
G6M87_27360	COG3300	MHYT domain
G6M87_27380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_27385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6M87_27395	COG0583	DNA-binding transcription factor activity
G6M87_27410	COG0657	acetylesterase activity
G6M87_27420	COG4166	transmembrane transport
G6M87_27435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_27440	COG0601	transmembrane transport
G6M87_27445	COG0747	negative chemotaxis
G6M87_27460	COG1960	acyl-CoA dehydrogenase activity
G6M87_27465	COG0824	Thioesterase
G6M87_27465	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6M87_27470	COG3246	L-lysine catabolic process to acetate
G6M87_27480	COG0583	DNA-binding transcription factor activity
G6M87_27490	COG1609	Transcriptional regulator
G6M87_27495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_27500	COG1126	abc transporter atp-binding protein
G6M87_27505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_27525	COG3842	ATPase activity
G6M87_27535	COG0395	ABC-type sugar transport system, permease component
G6M87_27550	COG1461	Dihydroxyacetone kinase
G6M87_27555	COG2376	Dihydroxyacetone kinase
G6M87_27565	COG0673	inositol 2-dehydrogenase activity
G6M87_27570	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_27575	COG1129	ABC transporter
G6M87_27585	COG1879	ABC-type sugar transport system periplasmic component
G6M87_27590	COG0287	Prephenate dehydrogenase
G6M87_27600	COG1850	ribulose-bisphosphate carboxylase activity
G6M87_27605	COG2186	Transcriptional regulator
G6M87_27615	COG1968	undecaprenyl-diphosphatase activity
G6M87_27620	COG2824	Alkylphosphonate utilization operon protein PhnA
G6M87_27635	COG0352	thiamine-phosphate diphosphorylase activity
G6M87_27640	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
G6M87_27650	COG0625	glutathione transferase activity
G6M87_27665	COG2204	response regulator
G6M87_27670	COG4191	Histidine kinase
G6M87_27675	COG1301	dicarboxylic acid transport
G6M87_27680	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
G6M87_27685	COG0577	efflux transmembrane transporter activity
G6M87_27685	COG1136	(ABC) transporter
G6M87_27695	COG1136	(ABC) transporter
G6M87_27705	COG2169	Transcriptional regulator
G6M87_27710	COG1414	Transcriptional regulator
G6M87_27720	COG0747	negative chemotaxis
G6M87_27740	COG4774	siderophore transport
G6M87_27750	COG2819	hydrolase of the alpha beta superfamily
G6M87_27755	COG1120	ATPase activity
G6M87_27760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6M87_27770	COG1522	sequence-specific DNA binding
G6M87_27775	COG4172	Belongs to the ABC transporter superfamily
G6M87_27780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_27785	COG0601	transmembrane transport
G6M87_27815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_27820	COG0251	oxidation-reduction process
G6M87_27840	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_27850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_27855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_27865	COG0454	-acetyltransferase
G6M87_27880	COG1414	Transcriptional regulator
G6M87_27895	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G6M87_27965	COG2207	Transcriptional regulator
G6M87_28000	COG1136	(ABC) transporter
G6M87_28000	COG0577	efflux transmembrane transporter activity
G6M87_28005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_28020	COG0436	Aminotransferase
G6M87_28030	COG0583	DNA-binding transcription factor activity
G6M87_28045	COG0765	amino acid transport
G6M87_28050	COG0765	amino acid transport
G6M87_28055	COG1126	abc transporter atp-binding protein
G6M87_28075	COG2197	response regulator
G6M87_28080	COG4585	Histidine kinase
G6M87_28090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_28100	COG0006	proline dipeptidase activity
G6M87_28105	COG3842	ATPase activity
G6M87_28110	COG0395	ABC-type sugar transport system, permease component
G6M87_28125	COG0626	cystathionine gamma-synthase activity
G6M87_28130	COG2186	Transcriptional regulator
G6M87_28140	COG2755	lipolytic protein G-D-S-L family
G6M87_28140	COG0657	acetylesterase activity
G6M87_28160	COG3842	ATPase activity
G6M87_28170	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_28175	COG0395	ABC-type sugar transport system, permease component
G6M87_28195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_28200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_28205	COG1473	amidohydrolase
G6M87_28215	COG1126	abc transporter atp-binding protein
G6M87_28220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6M87_28230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_28235	COG1215	transferase activity, transferring glycosyl groups
G6M87_28245	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_28250	COG1129	ABC transporter
G6M87_28255	COG4213	ABC transporter substrate-binding protein
G6M87_28270	COG4993	Dehydrogenase
G6M87_28290	COG1940	carbohydrate kinase activity
G6M87_28290	COG1846	Transcriptional regulator
G6M87_28305	COG0395	ABC-type sugar transport system, permease component
G6M87_28360	COG0277	FAD linked oxidase domain protein
G6M87_28390	COG3344	reverse transcriptase
G6M87_28400	COG1902	pentaerythritol trinitrate reductase activity
G6M87_28445	COG0667	Aldo Keto reductase
G6M87_28460	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6M87_28460	COG1902	pentaerythritol trinitrate reductase activity
G6M87_28470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G6M87_28480	COG4176	ABC-type proline glycine betaine transport system permease component
G6M87_28485	COG4175	Glycine betaine
G6M87_28485	COG0517	IMP dehydrogenase activity
G6M87_28490	COG1278	Cold shock
G6M87_28495	COG5342	invasion associated locus B
G6M87_28535	COG1349	DNA-binding transcription factor activity
G6M87_28545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6M87_28560	COG1175	transmembrane transport
G6M87_28565	COG0395	ABC-type sugar transport system, permease component
G6M87_28570	COG2204	response regulator
G6M87_28575	COG4191	Histidine kinase
G6M87_28585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6M87_28595	COG1609	Transcriptional regulator
G6M87_28605	COG1175	transmembrane transport
G6M87_28610	COG0395	ABC-type sugar transport system, permease component
G6M87_28630	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6M87_28635	COG0625	glutathione transferase activity
G6M87_28655	COG3845	ABC transporter
G6M87_28665	COG1079	Belongs to the binding-protein-dependent transport system permease family
G6M87_28680	COG0243	molybdopterin cofactor binding
G6M87_28690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G6M87_28695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
G6M87_28705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_28710	COG0601	transmembrane transport
G6M87_28715	COG0747	negative chemotaxis
G6M87_28720	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
G6M87_28725	COG2971	BadF BadG BcrA BcrD
G6M87_28730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6M87_28735	COG1737	Transcriptional regulator
G6M87_28740	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_28750	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G6M87_28755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G6M87_28780	COG1116	anion transmembrane transporter activity
G6M87_28785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_28795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6M87_28800	COG0747	negative chemotaxis
G6M87_28805	COG4608	Belongs to the ABC transporter superfamily
G6M87_28825	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_28830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_28835	COG0601	transmembrane transport
G6M87_28850	COG0584	glycerophosphoryl diester phosphodiesterase
G6M87_28855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_28865	COG4172	Belongs to the ABC transporter superfamily
G6M87_28880	COG1609	Transcriptional regulator
G6M87_28895	COG2137	regulation of response to DNA damage stimulus
G6M87_28900	COG1802	Transcriptional regulator
G6M87_28905	COG1126	abc transporter atp-binding protein
G6M87_28910	COG0765	amino acid transport
G6M87_28915	COG0765	amino acid transport
G6M87_28925	COG1063	alcohol dehydrogenase
G6M87_28930	COG0246	Mannitol dehydrogenase
G6M87_28935	COG1312	Catalyzes the dehydration of D-mannonate
G6M87_28940	COG1802	Transcriptional regulator
G6M87_28945	COG0667	Aldo Keto reductase
G6M87_28955	COG1473	amidohydrolase
G6M87_28980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G6M87_28985	COG0667	Aldo Keto reductase
G6M87_28990	COG0583	DNA-binding transcription factor activity
G6M87_28995	COG0450	alkyl hydroperoxide reductase
G6M87_29015	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
G6M87_29015	COG2273	Hydrolase Family 16
G6M87_29020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_29025	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
G6M87_29030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G6M87_29035	COG2894	cell division
G6M87_29040	COG0850	regulation of cytokinetic process
G6M87_29045	COG0668	transmembrane transport
G6M87_29055	COG0252	asparaginase activity
G6M87_29065	COG1027	Aspartate ammonia-lyase
G6M87_29070	COG2186	Transcriptional regulator
G6M87_29100	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_29105	COG4172	Belongs to the ABC transporter superfamily
G6M87_29110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_29125	COG1802	Transcriptional regulator
G6M87_29130	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G6M87_29135	COG1522	sequence-specific DNA binding
G6M87_29145	COG0318	PFAM AMP-dependent synthetase and ligase
G6M87_29155	COG1802	Transcriptional regulator
G6M87_29160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_29165	COG1473	amidohydrolase
G6M87_29170	COG1126	abc transporter atp-binding protein
G6M87_29175	COG0765	amino acid transport
G6M87_29195	COG2226	methyltransferase
G6M87_29200	COG1120	ATPase activity
G6M87_29205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6M87_29215	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_29215	COG3185	4-Hydroxyphenylpyruvate dioxygenase
G6M87_29220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G6M87_29260	COG5383	Protein conserved in bacteria
G6M87_29265	COG0583	DNA-binding transcription factor activity
G6M87_29270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G6M87_29275	COG1454	alcohol dehydrogenase
G6M87_29285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6M87_29290	COG0747	negative chemotaxis
G6M87_29295	COG0601	transmembrane transport
G6M87_29300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_29305	COG0444	Belongs to the ABC transporter superfamily
G6M87_29310	COG4608	Belongs to the ABC transporter superfamily
G6M87_29330	COG0330	HflC and HflK could
G6M87_29340	COG2217	Heavy metal translocating P-type atpase
G6M87_29365	COG4789	Type iii secretion
G6M87_29375	COG4792	protein secretion
G6M87_29385	COG1987	bacterial-type flagellum assembly
G6M87_29390	COG4790	Type iii secretion
G6M87_29395	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G6M87_29415	COG4669	(LipO)protein
G6M87_29435	COG2207	Transcriptional regulator
G6M87_29460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G6M87_29465	COG0459	protein refolding
G6M87_29480	COG1301	dicarboxylic acid transport
G6M87_29485	COG0583	DNA-binding transcription factor activity
G6M87_29505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6M87_29515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G6M87_29520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G6M87_29525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6M87_29530	COG1120	ATPase activity
G6M87_29545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G6M87_29555	COG0535	radical SAM domain protein
G6M87_29560	COG0535	radical SAM domain protein
G6M87_29565	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
G6M87_29570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G6M87_29590	COG1064	alcohol dehydrogenase
G6M87_29610	COG3707	response regulator
G6M87_29615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_29620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_29625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_29630	COG1116	anion transmembrane transporter activity
G6M87_29635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6M87_29645	COG0243	molybdopterin cofactor binding
G6M87_29670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6M87_29680	COG4977	sequence-specific DNA binding
G6M87_29705	COG2011	ABC-type metal ion transport system permease component
G6M87_29710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G6M87_29715	COG1464	Belongs to the NlpA lipoprotein family
G6M87_29730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6M87_29730	COG4651	solute:proton antiporter activity
G6M87_29735	COG1063	alcohol dehydrogenase
G6M87_29745	COG0477	Major facilitator Superfamily
G6M87_29750	COG2186	Transcriptional regulator
G6M87_29755	COG2814	Major facilitator Superfamily
G6M87_29775	COG1940	carbohydrate kinase activity
G6M87_29785	COG2186	Transcriptional regulator
G6M87_29800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_29805	COG0405	Gamma-glutamyltransferase
G6M87_29820	COG0386	Belongs to the glutathione peroxidase family
G6M87_29825	COG4106	trans-aconitate 2-methyltransferase activity
G6M87_29835	COG1940	carbohydrate kinase activity
G6M87_29850	COG4952	isomerase
G6M87_29855	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_29855	COG3347	Dehydrogenase
G6M87_29860	COG1349	DNA-binding transcription factor activity
G6M87_29880	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_29895	COG0583	DNA-binding transcription factor activity
G6M87_29900	COG0625	glutathione transferase activity
G6M87_29925	COG0673	inositol 2-dehydrogenase activity
G6M87_29930	COG1309	transcriptional regulator
G6M87_29940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6M87_29945	COG1063	alcohol dehydrogenase
G6M87_29950	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_29955	COG4948	Mandelate Racemase Muconate Lactonizing
G6M87_29965	COG3842	ATPase activity
G6M87_29970	COG0395	ABC-type sugar transport system, permease component
G6M87_29975	COG1175	transmembrane transport
G6M87_29990	COG1070	Carbohydrate kinase
G6M87_30000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G6M87_30005	COG0667	Aldo Keto reductase
G6M87_30015	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_30020	COG1129	ABC transporter
G6M87_30035	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
G6M87_30055	COG1802	Transcriptional regulator
G6M87_30060	COG1914	H( )-stimulated, divalent metal cation uptake system
G6M87_30065	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_30070	COG4336	lyase activity
G6M87_30075	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
G6M87_30080	COG4770	biotin carboxylase activity
G6M87_30100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6M87_30115	COG1802	Transcriptional regulator
G6M87_30120	COG0747	negative chemotaxis
G6M87_30125	COG0601	transmembrane transport
G6M87_30130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_30140	COG4608	Belongs to the ABC transporter superfamily
G6M87_30150	COG0154	amidase activity
G6M87_30170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_30180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_30185	COG2828	Protein conserved in bacteria
G6M87_30190	COG0583	DNA-binding transcription factor activity
G6M87_30200	COG2353	YceI-like domain
G6M87_30230	COG1802	Transcriptional regulator
G6M87_30240	COG1122	ATPase activity
G6M87_30245	COG4120	Belongs to the binding-protein-dependent transport system permease family
G6M87_30270	COG5001	Diguanylate cyclase
G6M87_30280	COG1312	Catalyzes the dehydration of D-mannonate
G6M87_30285	COG2186	Transcriptional regulator
G6M87_30290	COG3250	beta-galactosidase activity
G6M87_30295	COG3459	Glycosyltransferase 36 associated
G6M87_30300	COG0656	L-ascorbic acid biosynthetic process
G6M87_30305	COG2814	Major facilitator Superfamily
G6M87_30310	COG0583	DNA-binding transcription factor activity
G6M87_30335	COG1132	(ABC) transporter
G6M87_30340	COG1032	radical SAM domain protein
G6M87_30360	COG2223	nitrite transmembrane transporter activity
G6M87_30370	COG2169	Transcriptional regulator
G6M87_30405	COG3634	alkyl hydroperoxide reductase activity
G6M87_30410	COG0583	DNA-binding transcription factor activity
G6M87_30425	COG2197	response regulator
G6M87_30430	COG2267	carboxylic ester hydrolase activity
G6M87_30440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_30455	COG3743	rRNA binding
G6M87_30455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G6M87_30475	COG2224	Isocitrate lyase
G6M87_30490	COG4585	Histidine kinase
G6M87_30495	COG1879	ABC-type sugar transport system periplasmic component
G6M87_30500	COG1129	ABC transporter
G6M87_30505	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_30515	COG3386	PFAM SMP-30 Gluconolaconase
G6M87_30520	COG1802	Transcriptional regulator
G6M87_30535	COG0765	amino acid transport
G6M87_30540	COG1126	abc transporter atp-binding protein
G6M87_30550	COG1063	alcohol dehydrogenase
G6M87_30555	COG2721	sulfolactate sulfo-lyase activity
G6M87_30560	COG1396	sequence-specific DNA binding
G6M87_30570	COG1024	Enoyl-CoA hydratase
G6M87_30575	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6M87_30585	COG2986	histidine ammonia-lyase
G6M87_30620	COG2030	dehydratase
G6M87_30630	COG2986	histidine ammonia-lyase
G6M87_30635	COG1732	Glycine betaine
G6M87_30655	COG1174	glycine betaine transport
G6M87_30690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6M87_30695	COG0840	transmembrane signaling receptor activity
G6M87_30720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6M87_30725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G6M87_30740	COG0069	glutamate synthase activity
G6M87_30745	COG2218	PFAM glutamate synthase alpha subunit domain protein
G6M87_30750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G6M87_30760	COG4977	sequence-specific DNA binding
G6M87_30765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_30770	COG4311	Sarcosine oxidase, delta subunit
G6M87_30775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G6M87_30775	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6M87_30790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6M87_30795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6M87_30800	COG1121	(ABC) transporter
G6M87_30805	COG0803	Belongs to the bacterial solute-binding protein 9 family
G6M87_30810	COG0463	Glycosyl transferase, family 2
G6M87_30830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G6M87_30835	COG1522	sequence-specific DNA binding
G6M87_30840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6M87_30845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_30865	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_30875	COG1175	transmembrane transport
G6M87_30880	COG0395	ABC-type sugar transport system, permease component
G6M87_30885	COG3842	ATPase activity
G6M87_30925	COG0395	ABC-type sugar transport system, permease component
G6M87_30930	COG1175	transmembrane transport
G6M87_30945	COG1309	transcriptional regulator
G6M87_30950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6M87_30970	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_30995	COG0411	ABC transporter
G6M87_31025	COG2080	2 iron, 2 sulfur cluster binding
G6M87_31030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6M87_31030	COG2010	Cytochrome c
G6M87_31040	COG1846	Transcriptional regulator
G6M87_31080	COG1846	Transcriptional regulator
G6M87_31095	COG0411	ABC transporter
G6M87_31105	COG2188	Transcriptional regulator
G6M87_31110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G6M87_31120	COG0601	transmembrane transport
G6M87_31125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_31155	COG1116	anion transmembrane transporter activity
G6M87_31160	COG4191	Histidine kinase
G6M87_31165	COG4566	intracellular signal transduction
G6M87_31175	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G6M87_31180	COG1780	Probably involved in ribonucleotide reductase function
G6M87_31195	COG0671	phosphoesterase, PA-phosphatase related
G6M87_31200	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_31205	COG1177	transmembrane transport
G6M87_31215	COG1396	sequence-specific DNA binding
G6M87_31220	COG3842	ATPase activity
G6M87_31250	COG0626	cystathionine gamma-synthase activity
G6M87_31265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6M87_31285	COG1120	ATPase activity
G6M87_31310	COG4774	siderophore transport
G6M87_31315	COG2819	hydrolase of the alpha beta superfamily
G6M87_31320	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G6M87_31330	COG0625	glutathione transferase activity
G6M87_31340	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
G6M87_31355	COG1522	sequence-specific DNA binding
G6M87_31370	COG0840	transmembrane signaling receptor activity
G6M87_31385	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G6M87_31390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G6M87_31395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
G6M87_31395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
G6M87_31405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
G6M87_31415	COG1609	Transcriptional regulator
G6M87_31420	COG1063	alcohol dehydrogenase
G6M87_31440	COG0673	inositol 2-dehydrogenase activity
G6M87_31450	COG2390	Transcriptional regulator
G6M87_31455	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6M87_31460	COG3958	Transketolase
G6M87_31465	COG3959	Transketolase, thiamine diphosphate binding domain
G6M87_31470	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_31480	COG1129	ABC transporter
G6M87_31485	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_31490	COG0149	triose-phosphate isomerase activity
G6M87_31495	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_31500	COG1192	Involved in chromosome partitioning
G6M87_31505	COG1475	DNA binding
G6M87_31510	COG0640	Transcriptional regulator
G6M87_31515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6M87_31530	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6M87_31555	COG1238	metal cluster binding
G6M87_31645	COG0583	DNA-binding transcription factor activity
G6M87_31655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6M87_31660	COG1116	anion transmembrane transporter activity
G6M87_31665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6M87_31675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_31680	COG1028	Short-chain dehydrogenase reductase Sdr
G6M87_31710	COG1172	Belongs to the binding-protein-dependent transport system permease family
G6M87_31715	COG1129	ABC transporter
G6M87_31740	COG4172	Belongs to the ABC transporter superfamily
G6M87_31745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_31750	COG0601	transmembrane transport
G6M87_31760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_31765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6M87_31770	COG0583	DNA-binding transcription factor activity
G6M87_31780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6M87_31795	COG1132	(ABC) transporter
G6M87_31800	COG4172	Belongs to the ABC transporter superfamily
G6M87_31805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_31825	COG1082	Xylose isomerase domain protein TIM barrel
G6M87_31830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6M87_31835	COG0019	diaminopimelate decarboxylase activity
G6M87_31845	COG1475	DNA binding
G6M87_31855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6M87_31950	COG1475	DNA binding
G6M87_31975	COG2824	Alkylphosphonate utilization operon protein PhnA
G6M87_32000	COG5489	Protein of unknown function (DUF736)
G6M87_32050	COG0776	regulation of translation
G6M87_32055	COG3831	ATPase activity
G6M87_32125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_32130	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6M87_32135	COG1522	sequence-specific DNA binding
G6M87_32150	COG3842	ATPase activity
G6M87_32155	COG1177	transmembrane transport
G6M87_32160	COG1177	transmembrane transport
G6M87_32170	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_32175	COG1177	transmembrane transport
G6M87_32180	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
G6M87_32185	COG3842	ATPase activity
G6M87_32190	COG1012	belongs to the aldehyde dehydrogenase family
G6M87_32205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6M87_32225	COG1176	ABC-type spermidine putrescine transport system, permease component I
G6M87_32230	COG3842	ATPase activity
G6M87_32235	COG1840	ABC-type Fe3 transport system, periplasmic component
G6M87_32260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_32265	COG4172	Belongs to the ABC transporter superfamily
G6M87_32275	COG1064	alcohol dehydrogenase
G6M87_32285	COG3328	transposase activity
G6M87_32320	COG3328	transposase activity
G6M87_32370	COG2951	lytic endotransglycosylase activity
G6M87_32430	COG3158	transport of potassium into the cell
G6M87_32475	COG4584	PFAM Integrase catalytic
G6M87_32480	COG1484	DNA-dependent DNA replication
G6M87_32570	COG4584	PFAM Integrase catalytic
G6M87_32590	COG1522	sequence-specific DNA binding
G6M87_32610	COG1278	Cold shock
G6M87_32650	COG1793	dna ligase
G6M87_32650	COG3285	dna ligase
G6M87_32655	COG0071	Belongs to the small heat shock protein (HSP20) family
G6M87_32685	COG0587	DNA-directed DNA polymerase activity
G6M87_32735	COG1475	DNA binding
G6M87_32755	COG5489	Protein of unknown function (DUF736)
G6M87_32785	COG3831	ATPase activity
G6M87_32850	COG1283	sodium-dependent phosphate transmembrane transporter activity
G6M87_32860	COG0747	negative chemotaxis
G6M87_32870	COG4608	Belongs to the ABC transporter superfamily
G6M87_32880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_32885	COG0584	glycerophosphoryl diester phosphodiesterase
G6M87_32910	COG3158	transport of potassium into the cell
G6M87_32945	COG4584	PFAM Integrase catalytic
G6M87_32950	COG1484	DNA-dependent DNA replication
G6M87_33025	COG1192	Involved in chromosome partitioning
G6M87_33045	COG3505	Type IV secretory pathway VirD4
G6M87_33145	COG4372	Transposase
G6M87_33165	COG3328	transposase activity
G6M87_33180	COG4172	Belongs to the ABC transporter superfamily
G6M87_33185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6M87_33190	COG0601	transmembrane transport
G6M87_33210	COG0010	Belongs to the arginase family
G6M87_33275	COG3701	Conjugal transfer protein
G6M87_33280	COG3846	protein secretion by the type IV secretion system
G6M87_33290	COG5314	conjugation
G6M87_33295	COG3451	type IV secretory pathway VirB4
G6M87_33310	COG4962	Type ii secretion system protein e