locus-tag	class	description
F3X89_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F3X89_00020	COG0697	spore germination
F3X89_00025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3X89_00030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F3X89_00040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
F3X89_00045	COG1420	regulation of RNA biosynthetic process
F3X89_00055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F3X89_00060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_00065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3X89_00075	COG1137	ATPase activity
F3X89_00080	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3X89_00090	COG0616	signal peptide processing
F3X89_00095	COG0776	regulation of translation
F3X89_00120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F3X89_00125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3X89_00130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F3X89_00150	COG0280	phosphate acetyltransferase
F3X89_00150	COG0281	malic enzyme
F3X89_00155	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F3X89_00185	COG0180	Tryptophanyl-tRNA synthetase
F3X89_00195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F3X89_00220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3X89_00225	COG1702	phosphate starvation-inducible protein PhoH
F3X89_00230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F3X89_00240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F3X89_00245	COG1396	sequence-specific DNA binding
F3X89_00250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F3X89_00255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F3X89_00265	COG0071	Belongs to the small heat shock protein (HSP20) family
F3X89_00275	COG0840	transmembrane signaling receptor activity
F3X89_00280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_00290	COG0242	peptide deformylase activity
F3X89_00305	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F3X89_00310	COG0101	tRNA pseudouridine synthase activity
F3X89_00315	COG0579	oxidoreductase
F3X89_00325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_00330	COG2171	N-acyltransferase activity
F3X89_00340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3X89_00360	COG0300	oxidoreductase activity
F3X89_00365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F3X89_00380	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F3X89_00385	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F3X89_00390	COG3708	Transcriptional regulator
F3X89_00390	COG2207	Transcriptional regulator
F3X89_00400	COG0706	membrane insertase activity
F3X89_00405	COG0594	ribonuclease P activity
F3X89_00410	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F3X89_00415	COG2972	Histidine kinase
F3X89_00415	COG0840	transmembrane signaling receptor activity
F3X89_00440	COG1733	regulation of RNA biosynthetic process
F3X89_00460	COG0477	Major facilitator Superfamily
F3X89_00480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3X89_00490	COG0583	DNA-binding transcription factor activity
F3X89_00495	COG0300	oxidoreductase activity
F3X89_00500	COG0667	Aldo Keto reductase
F3X89_00510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_00515	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_00520	COG3938	Belongs to the proline racemase family
F3X89_00550	COG1072	(Pantothenic acid kinase))
F3X89_00555	COG0418	dihydroorotase activity
F3X89_00565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3X89_00575	COG0166	Belongs to the GPI family
F3X89_00580	COG0318	PFAM AMP-dependent synthetase and ligase
F3X89_00590	COG0346	lactoylglutathione lyase activity
F3X89_00595	COG3795	YCII-related domain
F3X89_00600	COG1174	glycine betaine transport
F3X89_00605	COG1125	glycine betaine transport
F3X89_00610	COG1174	glycine betaine transport
F3X89_00615	COG1732	Glycine betaine
F3X89_00620	COG0583	DNA-binding transcription factor activity
F3X89_00660	COG2326	polyphosphate kinase activity
F3X89_00665	COG5002	protein histidine kinase activity
F3X89_00675	COG0573	inorganic phosphate transmembrane transporter activity
F3X89_00680	COG0581	inorganic phosphate transmembrane transporter activity
F3X89_00685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3X89_00690	COG0704	Plays a role in the regulation of phosphate uptake
F3X89_00695	COG0745	RESPONSE REGULATOR receiver
F3X89_00710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_00715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3X89_00720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
F3X89_00725	COG2967	ApaG domain
F3X89_00735	COG0717	Belongs to the dCTP deaminase family
F3X89_00745	COG0110	maltose O-acetyltransferase activity
F3X89_00780	COG0167	dihydroorotate dehydrogenase activity
F3X89_00785	COG0534	Mate efflux family protein
F3X89_00805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
F3X89_00815	COG0174	glutamine synthetase
F3X89_00820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3X89_00825	COG1959	2 iron, 2 sulfur cluster binding
F3X89_00830	COG1201	RNA secondary structure unwinding
F3X89_00855	COG0730	response to heat
F3X89_00870	COG1960	acyl-CoA dehydrogenase activity
F3X89_00875	COG0183	Belongs to the thiolase family
F3X89_00880	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3X89_00880	COG1024	Enoyl-CoA hydratase
F3X89_00895	COG1970	mechanosensitive ion channel activity
F3X89_00900	COG0436	Aminotransferase
F3X89_00935	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_00945	COG1024	Enoyl-CoA hydratase
F3X89_00975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3X89_00975	COG4651	solute:proton antiporter activity
F3X89_00985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3X89_00990	COG0840	transmembrane signaling receptor activity
F3X89_01000	COG0745	RESPONSE REGULATOR receiver
F3X89_01005	COG0643	Histidine kinase
F3X89_01005	COG2198	Histidine kinase
F3X89_01010	COG0835	chemotaxis
F3X89_01015	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F3X89_01020	COG2201	protein-glutamate methylesterase activity
F3X89_01025	COG0745	RESPONSE REGULATOR receiver
F3X89_01030	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
F3X89_01040	COG1766	The M ring may be actively involved in energy transduction
F3X89_01045	COG2771	luxR family
F3X89_01060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3X89_01065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3X89_01070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3X89_01075	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F3X89_01080	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
F3X89_01085	COG4786	Flagellar basal body rod
F3X89_01090	COG1157	protein secretion by the type III secretion system
F3X89_01100	COG1815	bacterial-type flagellum-dependent cell motility
F3X89_01105	COG1558	bacterial-type flagellum-dependent cell motility
F3X89_01110	COG1677	Flagellar hook-basal body complex protein FliE
F3X89_01115	COG4786	Flagellar basal body rod
F3X89_01120	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
F3X89_01125	COG1706	bacterial-type flagellum-dependent cell motility
F3X89_01135	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
F3X89_01145	COG1338	Plays a role in the flagellum-specific transport system
F3X89_01165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3X89_01175	COG0076	glutamate decarboxylase activity
F3X89_01185	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3X89_01220	COG1749	Flagellar hook protein flgE
F3X89_01240	COG5443	negative regulation of bacterial-type flagellum assembly
F3X89_01250	COG4794	Type iii secretion
F3X89_01255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F3X89_01260	COG1684	flagellar biosynthetic protein fliR
F3X89_01295	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F3X89_01300	COG1609	Transcriptional regulator
F3X89_01305	COG1653	transport
F3X89_01310	COG1175	transmembrane transport
F3X89_01315	COG0395	ABC-type sugar transport system, permease component
F3X89_01320	COG0366	Alpha amylase catalytic
F3X89_01325	COG3842	ATPase activity
F3X89_01345	COG0129	dihydroxy-acid dehydratase activity
F3X89_01350	COG0363	glucosamine-6-phosphate deaminase activity
F3X89_01355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3X89_01360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_01370	COG2081	HI0933 family
F3X89_01380	COG0840	transmembrane signaling receptor activity
F3X89_01380	COG2972	Histidine kinase
F3X89_01395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3X89_01400	COG3842	ATPase activity
F3X89_01405	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_01410	COG1177	transmembrane transport
F3X89_01420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_01425	COG0513	Belongs to the DEAD box helicase family
F3X89_01435	COG2205	protein histidine kinase activity
F3X89_01465	COG4269	membrane
F3X89_01475	COG1959	2 iron, 2 sulfur cluster binding
F3X89_01480	COG0747	negative chemotaxis
F3X89_01485	COG0601	transmembrane transport
F3X89_01490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_01495	COG0444	Belongs to the ABC transporter superfamily
F3X89_01500	COG4608	Belongs to the ABC transporter superfamily
F3X89_01505	COG3265	gluconokinase activity
F3X89_01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_01515	COG1755	Isoprenylcysteine carboxyl methyltransferase
F3X89_01530	COG1595	DNA-templated transcription, initiation
F3X89_01545	COG0583	DNA-binding transcription factor activity
F3X89_01555	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F3X89_01565	COG0477	Major facilitator Superfamily
F3X89_01595	COG0583	DNA-binding transcription factor activity
F3X89_01610	COG0488	(ABC) transporter
F3X89_01645	COG0306	phosphate transporter
F3X89_01660	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3X89_01665	COG0583	DNA-binding transcription factor activity
F3X89_01670	COG0277	FAD linked oxidase domain protein
F3X89_01675	COG0277	FAD linked oxidase domain protein
F3X89_01680	COG0247	lactate metabolic process
F3X89_01695	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_01700	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_01705	COG2818	Glycosylase
F3X89_01720	COG0667	Aldo Keto reductase
F3X89_01725	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_01725	COG3321	synthase
F3X89_01725	COG0604	alcohol dehydrogenase
F3X89_01730	COG0583	DNA-binding transcription factor activity
F3X89_01755	COG0124	histidyl-tRNA synthetase
F3X89_01760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
F3X89_01765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F3X89_01780	COG2259	Doxx family
F3X89_01785	COG0625	glutathione transferase activity
F3X89_01800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F3X89_01815	COG0196	riboflavin kinase activity
F3X89_01850	COG0590	tRNA wobble adenosine to inosine editing
F3X89_01855	COG1187	pseudouridine synthase activity
F3X89_01860	COG0742	ribosomal rna small subunit methyltransferase
F3X89_01870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3X89_01870	COG0475	glutathione-regulated potassium exporter activity
F3X89_01875	COG0312	modulator of DNA gyrase
F3X89_01880	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_01890	COG1519	Transferase
F3X89_01900	COG1663	tetraacyldisaccharide 4'-kinase activity
F3X89_01910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F3X89_01915	COG0745	RESPONSE REGULATOR receiver
F3X89_01920	COG5001	Diguanylate cyclase
F3X89_01920	COG3300	MHYT domain
F3X89_01925	COG1522	sequence-specific DNA binding
F3X89_01930	COG0137	argininosuccinate synthase activity
F3X89_01940	COG3386	PFAM SMP-30 Gluconolaconase
F3X89_01945	COG0800	Aldolase
F3X89_01950	COG3734	2-keto-3-deoxy-galactonokinase
F3X89_01955	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_01960	COG1414	Transcriptional regulator
F3X89_01965	COG2197	response regulator
F3X89_01970	COG0489	protein tyrosine kinase activity
F3X89_01975	COG0598	Magnesium transport protein CorA
F3X89_01980	COG3158	transport of potassium into the cell
F3X89_01995	COG0356	it plays a direct role in the translocation of protons across the membrane
F3X89_02000	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3X89_02005	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3X89_02010	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F3X89_02020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F3X89_02040	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3X89_02045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
F3X89_02055	COG0142	geranyltranstransferase activity
F3X89_02075	COG1396	sequence-specific DNA binding
F3X89_02110	COG0752	glycyl-tRNA synthetase alpha subunit
F3X89_02115	COG1704	LemA family
F3X89_02120	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F3X89_02135	COG0751	glycine-tRNA ligase activity
F3X89_02140	COG1683	Conserved Protein
F3X89_02145	COG0840	transmembrane signaling receptor activity
F3X89_02155	COG0151	Belongs to the GarS family
F3X89_02160	COG2183	response to ionizing radiation
F3X89_02165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3X89_02185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F3X89_02210	COG0277	FAD linked oxidase domain protein
F3X89_02215	COG0009	L-threonylcarbamoyladenylate synthase
F3X89_02230	COG4638	Rieske (2fe-2S)
F3X89_02255	COG1960	acyl-CoA dehydrogenase activity
F3X89_02265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3X89_02275	COG0840	transmembrane signaling receptor activity
F3X89_02285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F3X89_02290	COG1741	Belongs to the pirin family
F3X89_02295	COG1722	exodeoxyribonuclease VII activity
F3X89_02300	COG0123	including yeast histone deacetylase and acetoin utilization protein
F3X89_02315	COG1268	BioY protein
F3X89_02320	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3X89_02325	COG1122	ATPase activity
F3X89_02330	COG3214	Protein conserved in bacteria
F3X89_02335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3X89_02335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3X89_02340	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F3X89_02350	COG0406	alpha-ribazole phosphatase activity
F3X89_02355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3X89_02360	COG0484	heat shock protein binding
F3X89_02370	COG0259	pyridoxamine-phosphate oxidase activity
F3X89_02380	COG1686	Belongs to the peptidase S11 family
F3X89_02390	COG0312	modulator of DNA gyrase
F3X89_02400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3X89_02405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3X89_02410	COG0109	protoheme IX farnesyltransferase activity
F3X89_02415	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
F3X89_02425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_02430	COG0640	Transcriptional regulator
F3X89_02455	COG3346	SURF1 family
F3X89_02460	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F3X89_02465	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3X89_02470	COG0328	RNA-DNA hybrid ribonuclease activity
F3X89_02485	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3X89_02495	COG1121	(ABC) transporter
F3X89_02500	COG0678	peroxiredoxin activity
F3X89_02500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3X89_02510	COG1678	Uncharacterized ACR, COG1678
F3X89_02530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_02535	COG0612	Peptidase, M16
F3X89_02550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_02560	COG1268	BioY protein
F3X89_02570	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3X89_02590	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F3X89_02605	COG1194	a g-specific adenine glycosylase
F3X89_02615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3X89_02620	COG1196	nuclear chromosome segregation
F3X89_02625	COG1253	flavin adenine dinucleotide binding
F3X89_02640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3X89_02640	COG0574	Belongs to the PEP-utilizing enzyme family
F3X89_02685	COG0463	Glycosyl transferase, family 2
F3X89_02710	COG1956	GAF domain-containing protein
F3X89_02720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3X89_02740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3X89_02755	COG0477	Major facilitator Superfamily
F3X89_02765	COG2895	sulfate adenylyltransferase (ATP) activity
F3X89_02770	COG0175	sulfate reduction
F3X89_02775	COG0175	sulfate reduction
F3X89_02780	COG1959	2 iron, 2 sulfur cluster binding
F3X89_02800	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
F3X89_02805	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_02810	COG0625	glutathione transferase activity
F3X89_02815	COG1309	transcriptional regulator
F3X89_02830	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F3X89_02835	COG1063	alcohol dehydrogenase
F3X89_02855	COG1349	DNA-binding transcription factor activity
F3X89_02865	COG0625	glutathione transferase activity
F3X89_02885	COG0583	DNA-binding transcription factor activity
F3X89_02900	COG1960	acyl-CoA dehydrogenase activity
F3X89_02905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3X89_02945	COG1793	dna ligase
F3X89_02970	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_02975	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_02980	COG1846	Transcriptional regulator
F3X89_02985	COG1764	response to oxidative stress
F3X89_03000	COG1846	Transcriptional regulator
F3X89_03015	COG0433	COG0433 Predicted ATPase
F3X89_03030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F3X89_03035	COG4106	trans-aconitate 2-methyltransferase activity
F3X89_03045	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3X89_03050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_03060	COG2814	Major facilitator Superfamily
F3X89_03095	COG1278	Cold shock
F3X89_03100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3X89_03110	COG2207	Transcriptional regulator
F3X89_03115	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_03135	COG2010	Cytochrome c
F3X89_03170	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F3X89_03205	COG0484	heat shock protein binding
F3X89_03220	COG2514	catechol 2,3-dioxygenase activity
F3X89_03225	COG1272	protein, Hemolysin III
F3X89_03240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3X89_03240	COG2111	Na H antiporter
F3X89_03245	COG2111	Na H antiporter
F3X89_03250	COG1006	Multisubunit Na H antiporter MnhC subunit
F3X89_03255	COG0651	ATP synthesis coupled electron transport
F3X89_03260	COG1863	multisubunit Na H antiporter MnhE subunit
F3X89_03265	COG2212	antiporter activity
F3X89_03270	COG1320	monovalent cation:proton antiporter activity
F3X89_03275	COG4957	zinc ion binding
F3X89_03280	COG2166	iron-sulfur cluster assembly
F3X89_03290	COG2205	protein histidine kinase activity
F3X89_03325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3X89_03330	COG2983	Belongs to the UPF0260 family
F3X89_03360	COG4235	cytochrome complex assembly
F3X89_03365	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F3X89_03370	COG1138	Cytochrome C-type biogenesis protein
F3X89_03375	COG3088	subunit of a heme lyase
F3X89_03380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_03385	COG0745	RESPONSE REGULATOR receiver
F3X89_03390	COG2205	protein histidine kinase activity
F3X89_03395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F3X89_03400	COG2202	Pas domain
F3X89_03400	COG2205	protein histidine kinase activity
F3X89_03405	COG0308	aminopeptidase N
F3X89_03410	COG0840	transmembrane signaling receptor activity
F3X89_03410	COG3290	protein histidine kinase activity
F3X89_03430	COG1573	uracil-dna glycosylase
F3X89_03435	COG0443	Heat shock 70 kDa protein
F3X89_03445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_03450	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_03475	COG2239	Acts as a magnesium transporter
F3X89_03485	COG1733	regulation of RNA biosynthetic process
F3X89_03490	COG2814	Major facilitator Superfamily
F3X89_03500	COG0174	glutamine synthetase
F3X89_03515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3X89_03520	COG0463	Glycosyl transferase, family 2
F3X89_03530	COG4941	Belongs to the sigma-70 factor family
F3X89_03540	COG3795	YCII-related domain
F3X89_03555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3X89_03575	COG0705	Rhomboid family
F3X89_03575	COG0457	Tetratricopeptide repeat
F3X89_03580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3X89_03605	COG3718	enzyme involved in inositol metabolism
F3X89_03610	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_03615	COG3962	Belongs to the TPP enzyme family
F3X89_03620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_03775	COG0740	serine-type endopeptidase activity
F3X89_03875	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F3X89_03940	COG0798	PFAM Bile acid sodium symporter
F3X89_03950	COG0640	Transcriptional regulator
F3X89_03975	COG0741	lytic transglycosylase activity
F3X89_03980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_03985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
F3X89_03995	COG1758	RNA polymerase activity
F3X89_04015	COG0736	holo-[acyl-carrier-protein] synthase activity
F3X89_04020	COG0681	Belongs to the peptidase S26 family
F3X89_04025	COG0571	ribonuclease III activity
F3X89_04030	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3X89_04040	COG1381	Involved in DNA repair and RecF pathway recombination
F3X89_04050	COG1418	mRNA catabolic process
F3X89_04065	COG2032	superoxide dismutase activity
F3X89_04080	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F3X89_04085	COG0354	folic acid binding
F3X89_04110	COG1742	UPF0060 membrane protein
F3X89_04120	COG1183	phosphatidylcholine synthase activity
F3X89_04125	COG0688	phosphatidylethanolamine metabolic process
F3X89_04130	COG0671	phosphoesterase, PA-phosphatase related
F3X89_04135	COG5265	(ABC) transporter
F3X89_04155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3X89_04180	COG0215	cysteine-tRNA ligase activity
F3X89_04185	COG4221	oxidoreductase activity
F3X89_04190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F3X89_04195	COG1286	toxin biosynthetic process
F3X89_04205	COG1280	lysine exporter protein (LysE YggA)
F3X89_04210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3X89_04215	COG0305	Participates in initiation and elongation during chromosome replication
F3X89_04235	COG0359	binds to the 23S rRNA
F3X89_04245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F3X89_04250	COG0360	Binds together with S18 to 16S ribosomal RNA
F3X89_04270	COG0667	Aldo Keto reductase
F3X89_04275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3X89_04285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_04290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3X89_04295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3X89_04300	COG1561	YicC-like family, N-terminal region
F3X89_04305	COG0194	GDP metabolic process
F3X89_04310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3X89_04315	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F3X89_04325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F3X89_04340	COG0671	phosphoesterase, PA-phosphatase related
F3X89_04345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3X89_04355	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3X89_04370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3X89_04370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
F3X89_04375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3X89_04380	COG1505	serine-type exopeptidase activity
F3X89_04390	COG0488	(ABC) transporter
F3X89_04405	COG0105	UTP biosynthetic process
F3X89_04425	COG0314	molybdopterin synthase activity
F3X89_04435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3X89_04440	COG0322	excinuclease ABC activity
F3X89_04445	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_04455	COG0625	glutathione transferase activity
F3X89_04460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3X89_04465	COG0243	molybdopterin cofactor binding
F3X89_04475	COG3454	Phosphonate metabolism
F3X89_04480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3X89_04485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F3X89_04490	COG0628	permease
F3X89_04500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F3X89_04505	COG0248	Ppx GppA phosphatase
F3X89_04515	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3X89_04520	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F3X89_04525	COG2132	Multicopper oxidase
F3X89_04535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F3X89_04555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3X89_04560	COG3654	unkown
F3X89_04575	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
F3X89_04585	COG0113	porphobilinogen synthase activity
F3X89_04605	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F3X89_04610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F3X89_04615	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3X89_04615	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3X89_04625	COG0454	-acetyltransferase
F3X89_04640	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3X89_04645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3X89_04650	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
F3X89_04670	COG0416	fatty acid biosynthetic process
F3X89_04675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
F3X89_04680	COG0776	regulation of translation
F3X89_04735	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
F3X89_04740	COG4423	Transcription factor
F3X89_04750	COG0438	transferase activity, transferring glycosyl groups
F3X89_04790	COG1612	heme a metabolic process
F3X89_04800	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F3X89_04805	COG0010	Belongs to the arginase family
F3X89_04820	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F3X89_04825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F3X89_04840	COG1832	CoA-binding protein
F3X89_04860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3X89_04865	COG0573	inorganic phosphate transmembrane transporter activity
F3X89_04875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3X89_04885	COG3706	GGDEF domain
F3X89_04890	COG0740	serine-type endopeptidase activity
F3X89_04895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F3X89_04900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3X89_04905	COG0776	regulation of translation
F3X89_04910	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_04915	COG0667	Aldo Keto reductase
F3X89_04920	COG0420	3'-5' exonuclease activity
F3X89_04925	COG4717	serine-type aminopeptidase activity
F3X89_04935	COG0438	transferase activity, transferring glycosyl groups
F3X89_04935	COG1216	Glycosyl transferase, family 2
F3X89_04960	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_04965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_04970	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_04975	COG0649	NAD binding
F3X89_04985	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F3X89_04990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F3X89_04995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3X89_04995	COG3743	rRNA binding
F3X89_05005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F3X89_05010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3X89_05020	COG0713	ATP synthesis coupled electron transport
F3X89_05035	COG1007	ATP synthesis coupled electron transport
F3X89_05050	COG0346	lactoylglutathione lyase activity
F3X89_05060	COG0442	prolyl-tRNA aminoacylation
F3X89_05070	COG1136	(ABC) transporter
F3X89_05100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3X89_05120	COG0784	Response regulator, receiver
F3X89_05130	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F3X89_05135	COG2814	Major facilitator Superfamily
F3X89_05150	COG0557	exoribonuclease II activity
F3X89_05155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3X89_05160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3X89_05160	COG0758	DNA mediated transformation
F3X89_05165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F3X89_05175	COG0540	Belongs to the ATCase OTCase family
F3X89_05180	COG1960	acyl-CoA dehydrogenase activity
F3X89_05185	COG3609	addiction module antidote protein, CC2985 family
F3X89_05195	COG0456	acetyltransferase
F3X89_05210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F3X89_05215	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
F3X89_05220	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3X89_05225	COG0154	amidase activity
F3X89_05235	COG3811	Belongs to the UPF0386 family
F3X89_05245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3X89_05265	COG4765	Protein conserved in bacteria
F3X89_05280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F3X89_05295	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F3X89_05305	COG0436	Aminotransferase
F3X89_05310	COG1530	ribonuclease E activity
F3X89_05315	COG0860	N-Acetylmuramoyl-L-alanine amidase
F3X89_05320	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3X89_05330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F3X89_05360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3X89_05380	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3X89_05385	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3X89_05410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3X89_05420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F3X89_05425	COG0081	regulation of translation
F3X89_05430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F3X89_05435	COG0222	ribosome binding
F3X89_05440	COG0085	RNA polymerase activity
F3X89_05445	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F3X89_05455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F3X89_05460	COG0049	tRNA binding
F3X89_05465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F3X89_05470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F3X89_05475	COG0051	transcription antitermination factor activity, RNA binding
F3X89_05480	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F3X89_05485	COG0088	Forms part of the polypeptide exit tunnel
F3X89_05490	COG0089	rRNA binding
F3X89_05495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F3X89_05500	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F3X89_05505	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
F3X89_05510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F3X89_05515	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F3X89_05520	COG0255	Belongs to the universal ribosomal protein uL29 family
F3X89_05525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F3X89_05530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F3X89_05535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F3X89_05540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F3X89_05545	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F3X89_05550	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
F3X89_05555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F3X89_05560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F3X89_05565	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F3X89_05570	COG1841	ribosomal large subunit assembly
F3X89_05575	COG0200	Binds to the 23S rRNA
F3X89_05580	COG0201	protein transport
F3X89_05585	COG0563	adenylate kinase activity
F3X89_05590	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F3X89_05595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F3X89_05600	COG0202	RNA polymerase activity
F3X89_05605	COG0203	ribosomal protein L17
F3X89_05610	COG3739	integral membrane protein
F3X89_05625	COG1289	transmembrane transporter activity
F3X89_05635	COG1566	PFAM secretion protein HlyD family protein
F3X89_05640	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F3X89_05645	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3X89_05650	COG0129	dihydroxy-acid dehydratase activity
F3X89_05665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3X89_05685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_05705	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F3X89_05730	COG0488	(ABC) transporter
F3X89_05735	COG1253	flavin adenine dinucleotide binding
F3X89_05760	COG0789	Transcriptional regulator
F3X89_05775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_05785	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3X89_05790	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F3X89_05800	COG1546	Belongs to the CinA family
F3X89_05800	COG1058	Belongs to the CinA family
F3X89_05805	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3X89_05815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3X89_05830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3X89_05845	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_05855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3X89_05860	COG0583	DNA-binding transcription factor activity
F3X89_05865	COG0737	Belongs to the 5'-nucleotidase family
F3X89_05880	COG1522	sequence-specific DNA binding
F3X89_05885	COG0686	Belongs to the AlaDH PNT family
F3X89_05900	COG2897	thiosulfate sulfurtransferase activity
F3X89_05905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3X89_05910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3X89_05915	COG0300	oxidoreductase activity
F3X89_05920	COG3842	ATPase activity
F3X89_05925	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3X89_05930	COG0395	ABC-type sugar transport system, permease component
F3X89_05935	COG1175	transmembrane transport
F3X89_05940	COG1653	transport
F3X89_05990	COG2755	lipolytic protein G-D-S-L family
F3X89_05990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_05995	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3X89_06005	COG0525	valine-tRNA ligase activity
F3X89_06025	COG0316	Belongs to the HesB IscA family
F3X89_06030	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F3X89_06035	COG0018	arginyl-trna synthetase
F3X89_06045	COG1472	Belongs to the glycosyl hydrolase 3 family
F3X89_06050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F3X89_06060	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3X89_06065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F3X89_06070	COG0805	protein transport
F3X89_06075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3X89_06080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F3X89_06085	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3X89_06090	COG0739	heme binding
F3X89_06100	COG1862	Preprotein translocase
F3X89_06125	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
F3X89_06155	COG0544	peptidyl-prolyl cis-trans isomerase activity
F3X89_06175	COG2003	Belongs to the UPF0758 family
F3X89_06180	COG0024	Methionine aminopeptidase
F3X89_06185	COG1489	DNA binding
F3X89_06190	COG3243	poly(R)-hydroxyalkanoic acid synthase
F3X89_06200	COG0436	Aminotransferase
F3X89_06285	COG1278	Cold shock
F3X89_06320	COG1280	lysine exporter protein (LysE YggA)
F3X89_06325	COG1522	sequence-specific DNA binding
F3X89_06335	COG1126	abc transporter atp-binding protein
F3X89_06340	COG0765	amino acid transport
F3X89_06345	COG4597	amino acid ABC transporter
F3X89_06350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_06355	COG0626	cystathionine gamma-synthase activity
F3X89_06370	COG0596	Alpha beta hydrolase
F3X89_06395	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3X89_06405	COG0537	adenosine 5'-monophosphoramidase activity
F3X89_06430	COG0052	Belongs to the universal ribosomal protein uS2 family
F3X89_06435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F3X89_06440	COG0528	UMP kinase activity
F3X89_06445	COG0233	cytoplasmic translational termination
F3X89_06450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3X89_06460	COG0750	zinc metalloprotease
F3X89_06465	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3X89_06470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3X89_06475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3X89_06480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3X89_06485	COG3494	Protein of unknown function (DUF1009)
F3X89_06490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3X89_06505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3X89_06515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F3X89_06520	COG0148	phosphopyruvate hydratase activity
F3X89_06530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3X89_06535	COG0022	dehydrogenase e1 component
F3X89_06535	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3X89_06540	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3X89_06550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3X89_06565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F3X89_06580	COG2867	negative regulation of translational initiation
F3X89_06585	COG1546	Belongs to the CinA family
F3X89_06590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
F3X89_06590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F3X89_06600	COG3852	Histidine kinase
F3X89_06605	COG2204	response regulator
F3X89_06610	COG5000	phosphorelay sensor kinase activity
F3X89_06615	COG2204	response regulator
F3X89_06620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3X89_06625	COG1923	regulation of RNA biosynthetic process
F3X89_06630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3X89_06635	COG3956	TIGRFAM MazG family protein
F3X89_06655	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3X89_06700	COG0785	Cytochrome C biogenesis protein
F3X89_06705	COG0679	Auxin Efflux Carrier
F3X89_06710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_06715	COG1183	phosphatidylcholine synthase activity
F3X89_06725	COG3845	ABC transporter
F3X89_06730	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3X89_06735	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_06745	COG1879	ABC-type sugar transport system periplasmic component
F3X89_06750	COG1129	ABC transporter
F3X89_06755	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_06760	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_06765	COG2186	Transcriptional regulator
F3X89_06770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3X89_06775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3X89_06795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3X89_06805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3X89_06820	COG0583	DNA-binding transcription factor activity
F3X89_06845	COG0174	glutamine synthetase
F3X89_06850	COG0347	Belongs to the P(II) protein family
F3X89_06855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3X89_06855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3X89_06865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3X89_06870	COG0629	single-stranded DNA binding
F3X89_06875	COG2095	MarC family integral membrane protein
F3X89_06880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3X89_06900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F3X89_06915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F3X89_06920	COG0343	queuine tRNA-ribosyltransferase activity
F3X89_06945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3X89_06960	COG1132	(ABC) transporter
F3X89_06965	COG1132	(ABC) transporter
F3X89_06970	COG0583	DNA-binding transcription factor activity
F3X89_06995	COG0321	lipoyl(octanoyl) transferase activity
F3X89_06995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F3X89_07000	COG0084	hydrolase, TatD family'
F3X89_07005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_07010	COG0730	response to heat
F3X89_07020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F3X89_07055	COG2094	Belongs to the DNA glycosylase MPG family
F3X89_07085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3X89_07090	COG0134	indole-3-glycerol-phosphate synthase activity
F3X89_07095	COG0315	cyclic pyranopterin monophosphate synthase activity
F3X89_07105	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F3X89_07115	COG0372	Belongs to the citrate synthase family
F3X89_07120	COG0372	Belongs to the citrate synthase family
F3X89_07125	COG0583	DNA-binding transcription factor activity
F3X89_07145	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
F3X89_07160	COG0504	CTP synthase activity
F3X89_07165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3X89_07170	COG0149	triose-phosphate isomerase activity
F3X89_07180	COG0187	DNA topoisomerase II activity
F3X89_07190	COG0628	permease
F3X89_07225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F3X89_07235	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
F3X89_07245	COG0302	gtp cyclohydrolase
F3X89_07250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3X89_07255	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3X89_07280	COG2267	carboxylic ester hydrolase activity
F3X89_07295	COG1686	Belongs to the peptidase S11 family
F3X89_07315	COG1760	l-serine dehydratase
F3X89_07340	COG2239	Acts as a magnesium transporter
F3X89_07345	COG0242	peptide deformylase activity
F3X89_07360	COG0321	lipoyl(octanoyl) transferase activity
F3X89_07375	COG4770	biotin carboxylase activity
F3X89_07380	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F3X89_07385	COG1671	Belongs to the UPF0178 family
F3X89_07390	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3X89_07400	COG2259	Doxx family
F3X89_07405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3X89_07420	COG0546	phosphoglycolate phosphatase activity
F3X89_07440	COG0509	glycine decarboxylation via glycine cleavage system
F3X89_07445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3X89_07445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F3X89_07455	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_07470	COG0316	Belongs to the HesB IscA family
F3X89_07475	COG2151	metal-sulfur cluster biosynthetic enzyme
F3X89_07480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3X89_07485	COG0719	Fe-S assembly protein
F3X89_07490	COG0396	ATPase activity
F3X89_07500	COG0719	Fe-S assembly protein
F3X89_07510	COG2945	thiolester hydrolase activity
F3X89_07525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F3X89_07540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3X89_07545	COG2833	Protein of unknown function (DUF455)
F3X89_07550	COG1196	nuclear chromosome segregation
F3X89_07550	COG0739	heme binding
F3X89_07550	COG0741	lytic transglycosylase activity
F3X89_07555	COG0513	Belongs to the DEAD box helicase family
F3X89_07560	COG1051	belongs to the nudix hydrolase family
F3X89_07570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F3X89_07575	COG3608	succinylglutamate desuccinylase aspartoacylase
F3X89_07575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
F3X89_07590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F3X89_07595	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_07615	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3X89_07635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3X89_07640	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3X89_07645	COG0047	phosphoribosylformylglycinamidine synthase activity
F3X89_07655	COG1660	Displays ATPase and GTPase activities
F3X89_07665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3X89_07675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3X89_07700	COG2814	Major facilitator Superfamily
F3X89_07705	COG2814	Major facilitator Superfamily
F3X89_07715	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_07720	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_07725	COG0037	tRNA processing
F3X89_07730	COG2066	Belongs to the glutaminase family
F3X89_07735	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F3X89_07745	COG1304	FMN binding
F3X89_07755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F3X89_07770	COG0538	isocitrate dehydrogenase activity
F3X89_07785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F3X89_07790	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F3X89_07800	COG2313	pseudouridylate synthase activity
F3X89_07835	COG3106	COG3106 Predicted ATPase
F3X89_07840	COG3768	UPF0283 membrane protein
F3X89_07860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3X89_07870	COG0633	Ferredoxin
F3X89_07900	COG3507	Belongs to the glycosyl hydrolase 43 family
F3X89_07905	COG0667	Aldo Keto reductase
F3X89_07910	COG0673	inositol 2-dehydrogenase activity
F3X89_07930	COG0395	ABC-type sugar transport system, permease component
F3X89_07935	COG1175	transmembrane transport
F3X89_07950	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3X89_07960	COG0456	acetyltransferase
F3X89_07975	COG1127	ABC transporter
F3X89_07980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3X89_07985	COG2814	Major facilitator Superfamily
F3X89_08000	COG0280	phosphate acetyltransferase
F3X89_08000	COG0281	malic enzyme
F3X89_08015	COG0823	Involved in the tonB-independent uptake of proteins
F3X89_08025	COG1368	sulfuric ester hydrolase activity
F3X89_08050	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
F3X89_08065	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F3X89_08070	COG0546	phosphoglycolate phosphatase activity
F3X89_08075	COG2989	Protein conserved in bacteria
F3X89_08080	COG0114	fumarate hydratase activity
F3X89_08090	COG3706	GGDEF domain
F3X89_08105	COG1846	Transcriptional regulator
F3X89_08120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3X89_08130	COG2972	Histidine kinase
F3X89_08130	COG0840	transmembrane signaling receptor activity
F3X89_08135	COG0697	spore germination
F3X89_08140	COG0746	molybdenum cofactor guanylyltransferase activity
F3X89_08145	COG1763	Mo-molybdopterin cofactor biosynthetic process
F3X89_08155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_08170	COG5425	PFAM Usg family protein
F3X89_08185	COG0640	Transcriptional regulator
F3X89_08195	COG1116	anion transmembrane transporter activity
F3X89_08200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_08205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_08210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_08215	COG2084	Dehydrogenase
F3X89_08220	COG1522	sequence-specific DNA binding
F3X89_08225	COG1573	uracil-dna glycosylase
F3X89_08235	COG2202	Pas domain
F3X89_08235	COG2205	protein histidine kinase activity
F3X89_08245	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F3X89_08250	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F3X89_08265	COG0697	spore germination
F3X89_08280	COG0842	Transport permease protein
F3X89_08285	COG1131	(ABC) transporter
F3X89_08300	COG1607	acyl-coa hydrolase
F3X89_08330	COG2814	Major facilitator Superfamily
F3X89_08335	COG0556	nucleotide-excision repair
F3X89_08350	COG1278	Cold shock
F3X89_08355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3X89_08360	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3X89_08375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3X89_08380	COG1121	(ABC) transporter
F3X89_08390	COG0523	cobalamin synthesis protein
F3X89_08415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F3X89_08430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_08490	COG1917	Cupin 2, conserved barrel domain protein
F3X89_08515	COG1492	cobalamin metabolic process
F3X89_08525	COG4176	ABC-type proline glycine betaine transport system permease component
F3X89_08530	COG4175	Glycine betaine
F3X89_08530	COG0517	IMP dehydrogenase activity
F3X89_08535	COG0646	methionine synthase
F3X89_08535	COG1410	methionine synthase
F3X89_08545	COG0463	Glycosyl transferase, family 2
F3X89_08560	COG5598	trimethylamine methyltransferase
F3X89_08565	COG5012	cobalamin binding
F3X89_08595	COG1410	methionine synthase
F3X89_08595	COG0646	methionine synthase
F3X89_08615	COG0583	DNA-binding transcription factor activity
F3X89_08640	COG0745	RESPONSE REGULATOR receiver
F3X89_08645	COG3264	Mechanosensitive ion channel
F3X89_08645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F3X89_08670	COG1959	2 iron, 2 sulfur cluster binding
F3X89_08685	COG0384	phenazine biosynthesis protein PhzF
F3X89_08700	COG3842	ATPase activity
F3X89_08715	COG0667	Aldo Keto reductase
F3X89_08720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3X89_08735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3X89_08745	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F3X89_08755	COG2207	Transcriptional regulator
F3X89_08760	COG1064	alcohol dehydrogenase
F3X89_08765	COG1252	NADH dehydrogenase
F3X89_08775	COG1522	sequence-specific DNA binding
F3X89_08780	COG1794	racemase activity, acting on amino acids and derivatives
F3X89_08790	COG0456	acetyltransferase
F3X89_08800	COG2814	Major facilitator Superfamily
F3X89_08805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_08810	COG1733	regulation of RNA biosynthetic process
F3X89_08820	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3X89_08825	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_08860	COG0656	L-ascorbic acid biosynthetic process
F3X89_08870	COG0440	acetolactate synthase activity
F3X89_08875	COG0028	Belongs to the TPP enzyme family
F3X89_08885	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F3X89_08890	COG0560	Phosphoserine phosphatase
F3X89_08900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_08910	COG0330	HflC and HflK could
F3X89_08925	COG0463	Glycosyl transferase, family 2
F3X89_08935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_08945	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
F3X89_08965	COG0410	ABC transporter
F3X89_08980	COG0583	DNA-binding transcription factor activity
F3X89_08995	COG3238	Protein conserved in bacteria
F3X89_09005	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F3X89_09035	COG0277	FAD linked oxidase domain protein
F3X89_09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_09045	COG0765	amino acid transport
F3X89_09050	COG0765	amino acid transport
F3X89_09070	COG2885	chlorophyll binding
F3X89_09075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
F3X89_09080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_09085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_09090	COG0210	DNA helicase
F3X89_09105	COG1335	isochorismatase
F3X89_09120	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F3X89_09125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F3X89_09145	COG0006	proline dipeptidase activity
F3X89_09150	COG2264	protein methyltransferase activity
F3X89_09160	COG1999	signal sequence binding
F3X89_09165	COG0835	chemotaxis
F3X89_09180	COG1247	-acetyltransferase
F3X89_09185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3X89_09195	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3X89_09205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3X89_09210	COG0849	cell division
F3X89_09215	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F3X89_09220	COG1181	Belongs to the D-alanine--D-alanine ligase family
F3X89_09225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3X89_09230	COG0477	Major facilitator Superfamily
F3X89_09235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3X89_09240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F3X89_09245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F3X89_09255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
F3X89_09260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3X89_09270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3X89_09285	COG0275	rRNA processing
F3X89_09290	COG2001	Belongs to the MraZ family
F3X89_09310	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3X89_09325	COG1280	lysine exporter protein (LysE YggA)
F3X89_09345	COG4106	trans-aconitate 2-methyltransferase activity
F3X89_09360	COG0697	spore germination
F3X89_09370	COG2226	methyltransferase
F3X89_09395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3X89_09400	COG0028	Belongs to the TPP enzyme family
F3X89_09405	COG0251	oxidation-reduction process
F3X89_09420	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_09430	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_09435	COG0174	glutamine synthetase
F3X89_09465	COG2011	ABC-type metal ion transport system permease component
F3X89_09470	COG3842	ATPase activity
F3X89_09475	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F3X89_09485	COG1609	Transcriptional regulator
F3X89_09495	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F3X89_09505	COG0673	inositol 2-dehydrogenase activity
F3X89_09510	COG0395	ABC-type sugar transport system, permease component
F3X89_09515	COG1175	transmembrane transport
F3X89_09525	COG2971	BadF BadG BcrA BcrD
F3X89_09530	COG2188	Transcriptional regulator
F3X89_09545	COG4702	Belongs to the UPF0303 family
F3X89_09615	COG2264	protein methyltransferase activity
F3X89_09670	COG2968	Membrane
F3X89_09685	COG0432	Pfam Uncharacterised protein family UPF0047
F3X89_09690	COG5507	3-demethylubiquinone-9 3-methyltransferase
F3X89_09710	COG0072	phenylalanine-tRNA ligase activity
F3X89_09710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_09715	COG2207	Transcriptional regulator
F3X89_09715	COG1917	Cupin 2, conserved barrel domain protein
F3X89_09735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3X89_09740	COG1063	alcohol dehydrogenase
F3X89_09750	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_09755	COG0514	ATP-dependent DNA helicase (RecQ)
F3X89_09760	COG0358	DNA primase activity
F3X89_09775	COG0505	Belongs to the CarA family
F3X89_09785	COG0534	Mate efflux family protein
F3X89_09795	COG2321	neutral zinc metallopeptidase
F3X89_09810	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F3X89_09815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3X89_09835	COG1522	sequence-specific DNA binding
F3X89_09840	COG0492	ferredoxin-NADP+ reductase activity
F3X89_09845	COG0583	DNA-binding transcription factor activity
F3X89_09855	COG1902	pentaerythritol trinitrate reductase activity
F3X89_09865	COG0300	oxidoreductase activity
F3X89_09870	COG0583	DNA-binding transcription factor activity
F3X89_09880	COG0387	Pfam Sodium calcium exchanger
F3X89_09890	COG2133	pyrroloquinoline quinone binding
F3X89_09900	COG1278	Cold shock
F3X89_09910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_09925	COG1846	Transcriptional regulator
F3X89_09930	COG0745	RESPONSE REGULATOR receiver
F3X89_09935	COG2205	protein histidine kinase activity
F3X89_09945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_09965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F3X89_09975	COG1496	oxidoreductase activity
F3X89_09990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3X89_10010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
F3X89_10025	COG0193	aminoacyl-tRNA hydrolase activity
F3X89_10035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3X89_10055	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F3X89_10060	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
F3X89_10060	COG2857	Cytochrome c1
F3X89_10080	COG1132	(ABC) transporter
F3X89_10085	COG1132	(ABC) transporter
F3X89_10090	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3X89_10110	COG0408	coproporphyrinogen oxidase activity
F3X89_10125	COG0617	tRNA 3'-terminal CCA addition
F3X89_10140	COG0714	Associated with various cellular activities
F3X89_10160	COG0454	-acetyltransferase
F3X89_10175	COG0435	Glutathione S-transferase
F3X89_10215	COG1132	(ABC) transporter
F3X89_10220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3X89_10225	COG3135	benzoate transporter
F3X89_10230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3X89_10240	COG0740	serine-type endopeptidase activity
F3X89_10250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F3X89_10255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F3X89_10260	COG0778	Nitroreductase
F3X89_10270	COG0512	Glutamine amidotransferase of anthranilate synthase
F3X89_10270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3X89_10275	COG0488	(ABC) transporter
F3X89_10290	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F3X89_10295	COG2862	Uncharacterized protein family, UPF0114
F3X89_10310	COG2197	response regulator
F3X89_10335	COG1435	thymidine kinase activity
F3X89_10345	COG4176	ABC-type proline glycine betaine transport system permease component
F3X89_10350	COG4175	Glycine betaine
F3X89_10365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3X89_10370	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_10375	COG0366	Alpha amylase catalytic
F3X89_10385	COG0601	transmembrane transport
F3X89_10390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_10400	COG4608	Belongs to the ABC transporter superfamily
F3X89_10405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_10425	COG1846	Transcriptional regulator
F3X89_10430	COG1160	GTP binding
F3X89_10450	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3X89_10460	COG0024	Methionine aminopeptidase
F3X89_10480	COG4941	Belongs to the sigma-70 factor family
F3X89_10485	COG3795	YCII-related domain
F3X89_10495	COG1619	proteins homologs of microcin C7 resistance protein MccF
F3X89_10505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3X89_10510	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_10520	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_10535	COG0583	DNA-binding transcription factor activity
F3X89_10550	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_10565	COG2351	hydroxyisourate hydrolase activity
F3X89_10570	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F3X89_10580	COG3648	Uricase
F3X89_10580	COG3195	allantoin biosynthetic process
F3X89_10590	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3X89_10595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_10600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_10600	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F3X89_10605	COG0784	Response regulator, receiver
F3X89_10605	COG5002	protein histidine kinase activity
F3X89_10605	COG2205	protein histidine kinase activity
F3X89_10610	COG5598	trimethylamine methyltransferase
F3X89_10620	COG0513	Belongs to the DEAD box helicase family
F3X89_10635	COG2308	Evidence 4 Homologs of previously reported genes of
F3X89_10655	COG1132	(ABC) transporter
F3X89_10660	COG0129	dihydroxy-acid dehydratase activity
F3X89_10665	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_10675	COG4214	carbohydrate transport
F3X89_10705	COG0673	inositol 2-dehydrogenase activity
F3X89_10715	COG4213	ABC transporter substrate-binding protein
F3X89_10720	COG4214	carbohydrate transport
F3X89_10725	COG1129	ABC transporter
F3X89_10770	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F3X89_10790	COG0671	phosphoesterase, PA-phosphatase related
F3X89_10800	COG2194	sulfuric ester hydrolase activity
F3X89_10825	COG0406	alpha-ribazole phosphatase activity
F3X89_10870	COG0022	dehydrogenase e1 component
F3X89_10880	COG0038	chloride channel
F3X89_10900	COG2076	Multidrug Resistance protein
F3X89_10910	COG3842	ATPase activity
F3X89_10915	COG3833	ABC-type maltose transport systems, permease component
F3X89_10935	COG0673	inositol 2-dehydrogenase activity
F3X89_10990	COG4558	Periplasmic binding protein
F3X89_10995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_11000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F3X89_11025	COG0784	Response regulator, receiver
F3X89_11030	COG3920	Histidine kinase
F3X89_11030	COG2202	Pas domain
F3X89_11035	COG0493	'glutamate synthase
F3X89_11045	COG1309	transcriptional regulator
F3X89_11075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_11080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_11085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_11090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_11100	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F3X89_11105	COG0830	nickel cation binding
F3X89_11110	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F3X89_11115	COG3706	GGDEF domain
F3X89_11125	COG0804	urea catabolic process
F3X89_11130	COG1442	glycosyl transferase family 8
F3X89_11135	COG0832	Belongs to the urease beta subunit family
F3X89_11140	COG0831	urea catabolic process
F3X89_11145	COG0829	nickel cation binding
F3X89_11155	COG0411	ABC transporter
F3X89_11175	COG2198	Histidine kinase
F3X89_11175	COG5002	protein histidine kinase activity
F3X89_11175	COG0784	Response regulator, receiver
F3X89_11180	COG0745	RESPONSE REGULATOR receiver
F3X89_11185	COG0683	leucine binding
F3X89_11220	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3X89_11225	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3X89_11225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3X89_11230	COG4311	Sarcosine oxidase, delta subunit
F3X89_11235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_11295	COG0564	pseudouridine synthase activity
F3X89_11300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3X89_11310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F3X89_11320	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_11325	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3X89_11330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_11335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_11350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_11360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_11365	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_11375	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3X89_11395	COG0346	lactoylglutathione lyase activity
F3X89_11400	COG0251	oxidation-reduction process
F3X89_11425	COG0346	lactoylglutathione lyase activity
F3X89_11430	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F3X89_11435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_11450	COG1349	DNA-binding transcription factor activity
F3X89_11455	COG0583	DNA-binding transcription factor activity
F3X89_11460	COG2855	membrane
F3X89_11465	COG5001	Diguanylate cyclase
F3X89_11465	COG3300	MHYT domain
F3X89_11470	COG0129	dihydroxy-acid dehydratase activity
F3X89_11475	COG2084	Dehydrogenase
F3X89_11480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_11500	COG0583	DNA-binding transcription factor activity
F3X89_11510	COG1595	DNA-templated transcription, initiation
F3X89_11520	COG0697	spore germination
F3X89_11530	COG1846	Transcriptional regulator
F3X89_11550	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3X89_11555	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_11560	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_11600	COG0477	Major facilitator Superfamily
F3X89_11610	COG1278	Cold shock
F3X89_11620	COG0346	lactoylglutathione lyase activity
F3X89_11630	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_11665	COG2011	ABC-type metal ion transport system permease component
F3X89_11675	COG4521	taurine ABC transporter
F3X89_11685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_11690	COG0330	HflC and HflK could
F3X89_11695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_11705	COG2814	Major facilitator Superfamily
F3X89_11750	COG0482	sulfurtransferase activity
F3X89_11765	COG4589	Belongs to the CDS family
F3X89_11775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_11815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3X89_11820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3X89_11825	COG0037	tRNA processing
F3X89_11835	COG2885	chlorophyll binding
F3X89_11840	COG0823	Involved in the tonB-independent uptake of proteins
F3X89_11865	COG0824	Thioesterase
F3X89_11885	COG1268	BioY protein
F3X89_11890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F3X89_11895	COG2318	DinB family
F3X89_11900	COG0494	nUDIX hydrolase
F3X89_11905	COG1408	metallophosphoesterase
F3X89_11910	COG2255	four-way junction helicase activity
F3X89_11915	COG0632	four-way junction helicase activity
F3X89_11930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
F3X89_11935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_11940	COG0217	transcriptional regulatory protein
F3X89_11950	COG1692	metallophosphoesterase
F3X89_11960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_11985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_11995	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_12000	COG0300	oxidoreductase activity
F3X89_12050	COG0126	phosphoglycerate kinase activity
F3X89_12055	COG3588	fructose-bisphosphate aldolase
F3X89_12060	COG0384	phenazine biosynthesis protein PhzF
F3X89_12090	COG0254	rRNA binding
F3X89_12100	COG3422	double-strand break repair
F3X89_12125	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_12155	COG0640	Transcriptional regulator
F3X89_12170	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3X89_12175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3X89_12180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F3X89_12185	COG0457	Tetratricopeptide repeat
F3X89_12190	COG0596	Alpha beta hydrolase
F3X89_12195	COG0583	DNA-binding transcription factor activity
F3X89_12225	COG0469	pyruvate kinase activity
F3X89_12245	COG3750	Belongs to the UPF0335 family
F3X89_12275	COG2372	response to copper ion
F3X89_12280	COG0726	polysaccharide deacetylase
F3X89_12300	COG3108	Peptidase M15
F3X89_12315	COG0512	Glutamine amidotransferase of anthranilate synthase
F3X89_12315	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3X89_12335	COG5310	Homospermidine synthase
F3X89_12350	COG0737	Belongs to the 5'-nucleotidase family
F3X89_12355	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F3X89_12360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_12365	COG0330	HflC and HflK could
F3X89_12375	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3X89_12375	COG0517	IMP dehydrogenase activity
F3X89_12385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3X89_12390	COG2951	lytic endotransglycosylase activity
F3X89_12410	COG0069	glutamate synthase activity
F3X89_12410	COG0067	glutamate synthase
F3X89_12410	COG0070	glutamate synthase
F3X89_12430	COG0071	Belongs to the small heat shock protein (HSP20) family
F3X89_12440	COG1522	sequence-specific DNA binding
F3X89_12445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3X89_12500	COG0662	Cupin 2, conserved barrel domain protein
F3X89_12500	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3X89_12510	COG2307	Protein conserved in bacteria
F3X89_12510	COG2308	Evidence 4 Homologs of previously reported genes of
F3X89_12525	COG0058	SHG alpha-glucan phosphorylase activity
F3X89_12530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F3X89_12535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F3X89_12540	COG0297	glycogen (starch) synthase activity
F3X89_12545	COG0033	Phosphoglucomutase
F3X89_12550	COG1523	belongs to the glycosyl hydrolase 13 family
F3X89_12565	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F3X89_12565	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3X89_12580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_12590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F3X89_12600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_12605	COG2202	Pas domain
F3X89_12605	COG3920	Histidine kinase
F3X89_12630	COG5001	Diguanylate cyclase
F3X89_12635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
F3X89_12640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3X89_12645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3X89_12650	COG1609	Transcriptional regulator
F3X89_12655	COG1846	Transcriptional regulator
F3X89_12665	COG0523	cobalamin synthesis protein
F3X89_12675	COG1045	serine acetyltransferase
F3X89_12700	COG0583	DNA-binding transcription factor activity
F3X89_12710	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F3X89_12725	COG0800	Aldolase
F3X89_12730	COG2954	triphosphatase activity
F3X89_12740	COG1054	Belongs to the UPF0176 family
F3X89_12750	COG0431	NADPH-dependent FMN reductase
F3X89_12765	COG0673	inositol 2-dehydrogenase activity
F3X89_12775	COG1879	ABC-type sugar transport system periplasmic component
F3X89_12780	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_12790	COG1609	Transcriptional regulator
F3X89_12800	COG2115	Belongs to the xylose isomerase family
F3X89_12805	COG1070	Carbohydrate kinase
F3X89_12810	COG1609	Transcriptional regulator
F3X89_12835	COG1253	flavin adenine dinucleotide binding
F3X89_12845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3X89_12850	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3X89_12855	COG0673	inositol 2-dehydrogenase activity
F3X89_12860	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_12865	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_12885	COG0583	DNA-binding transcription factor activity
F3X89_12890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3X89_12895	COG3842	ATPase activity
F3X89_12900	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_12905	COG1177	transmembrane transport
F3X89_12925	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_12945	COG3254	rhamnose metabolic process
F3X89_12950	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_12955	COG3842	ATPase activity
F3X89_12960	COG0395	ABC-type sugar transport system, permease component
F3X89_12965	COG1175	transmembrane transport
F3X89_12995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3X89_13015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3X89_13025	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3X89_13045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_13060	COG0395	ABC-type sugar transport system, permease component
F3X89_13065	COG1175	transmembrane transport
F3X89_13075	COG2390	Transcriptional regulator
F3X89_13095	COG1940	carbohydrate kinase activity
F3X89_13100	COG3142	Participates in the control of copper homeostasis
F3X89_13115	COG2719	SpoVR family
F3X89_13120	COG2718	Belongs to the UPF0229 family
F3X89_13125	COG2766	serine protein kinase
F3X89_13140	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F3X89_13145	COG0424	maF-like protein
F3X89_13150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F3X89_13160	COG5328	Belongs to the UPF0262 family
F3X89_13165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F3X89_13175	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3X89_13200	COG2514	catechol 2,3-dioxygenase activity
F3X89_13205	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3X89_13215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_13235	COG1764	response to oxidative stress
F3X89_13240	COG2186	Transcriptional regulator
F3X89_13245	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_13250	COG0670	Belongs to the BI1 family
F3X89_13265	COG3781	membrane
F3X89_13270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F3X89_13275	COG2900	Belongs to the SlyX family
F3X89_13285	COG3842	ATPase activity
F3X89_13290	COG1175	transmembrane transport
F3X89_13305	COG1609	Transcriptional regulator
F3X89_13360	COG1396	sequence-specific DNA binding
F3X89_13380	COG1222	aaa ATPase
F3X89_13415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3X89_13415	COG0784	Response regulator, receiver
F3X89_13450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_13455	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3X89_13470	COG4221	oxidoreductase activity
F3X89_13475	COG4191	Histidine kinase
F3X89_13480	COG4566	intracellular signal transduction
F3X89_13485	COG4566	intracellular signal transduction
F3X89_13490	COG4566	intracellular signal transduction
F3X89_13495	COG0583	DNA-binding transcription factor activity
F3X89_13500	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_13555	COG0542	response to heat
F3X89_13565	COG2890	protein-(glutamine-N5) methyltransferase activity
F3X89_13570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F3X89_13580	COG0527	aspartate kinase activity
F3X89_13585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3X89_13600	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3X89_13615	COG2226	methyltransferase
F3X89_13630	COG0494	nUDIX hydrolase
F3X89_13640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F3X89_13645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3X89_13650	COG0653	protein targeting
F3X89_13655	COG0583	DNA-binding transcription factor activity
F3X89_13660	COG1942	4-Oxalocrotonate Tautomerase
F3X89_13665	COG0625	glutathione transferase activity
F3X89_13680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_13695	COG0681	Belongs to the peptidase S26 family
F3X89_13700	COG0667	Aldo Keto reductase
F3X89_13705	COG2264	protein methyltransferase activity
F3X89_13760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3X89_13765	COG1295	ribonuclease BN
F3X89_13770	COG0300	oxidoreductase activity
F3X89_13785	COG2086	electron transfer activity
F3X89_13795	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3X89_13800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3X89_13805	COG0165	Argininosuccinate lyase
F3X89_13840	COG2884	Cell division ATP-binding protein ftsE
F3X89_13860	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
F3X89_13880	COG0287	Prephenate dehydrogenase
F3X89_13885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F3X89_13890	COG2226	methyltransferase
F3X89_13895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_13905	COG2382	esterase
F3X89_13920	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F3X89_13955	COG4536	flavin adenine dinucleotide binding
F3X89_13960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
F3X89_13965	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F3X89_13970	COG4974	Belongs to the 'phage' integrase family
F3X89_13975	COG0825	malonyl-CoA metabolic process
F3X89_13980	COG3034	peptidoglycan biosynthetic process
F3X89_13990	COG0523	cobalamin synthesis protein
F3X89_13995	COG1686	Belongs to the peptidase S11 family
F3X89_14000	COG1473	amidohydrolase
F3X89_14030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F3X89_14040	COG0156	8-amino-7-oxononanoate synthase activity
F3X89_14065	COG0729	surface antigen
F3X89_14090	COG0010	Belongs to the arginase family
F3X89_14095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_14100	COG0835	chemotaxis
F3X89_14105	COG2223	nitrite transmembrane transporter activity
F3X89_14115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3X89_14120	COG3383	formate dehydrogenase (NAD+) activity
F3X89_14145	COG0640	Transcriptional regulator
F3X89_14180	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_14185	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_14190	COG1454	alcohol dehydrogenase
F3X89_14200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F3X89_14205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F3X89_14210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
F3X89_14215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F3X89_14220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F3X89_14255	COG4974	Belongs to the 'phage' integrase family
F3X89_14270	COG0612	Peptidase, M16
F3X89_14280	COG1280	lysine exporter protein (LysE YggA)
F3X89_14285	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_14300	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3X89_14315	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F3X89_14320	COG0045	succinate-CoA ligase (ADP-forming) activity
F3X89_14325	COG0039	L-malate dehydrogenase activity
F3X89_14330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3X89_14365	COG2264	protein methyltransferase activity
F3X89_14375	COG2350	Protein conserved in bacteria
F3X89_14380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F3X89_14385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F3X89_14390	COG0181	hydroxymethylbilane synthase activity
F3X89_14435	COG1872	DUF167
F3X89_14440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3X89_14450	COG1217	gtp-binding protein TYPA
F3X89_14460	COG0339	signal peptide processing
F3X89_14475	COG0137	argininosuccinate synthase activity
F3X89_14485	COG1280	lysine exporter protein (LysE YggA)
F3X89_14495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
F3X89_14510	COG2154	pterin-4-alpha-carbinolamine dehydratase
F3X89_14515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3X89_14520	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F3X89_14530	COG4181	ATPase activity
F3X89_14540	COG0670	Belongs to the BI1 family
F3X89_14565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3X89_14570	COG4133	protoheme IX ABC transporter activity
F3X89_14575	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3X89_14580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F3X89_14600	COG2917	probably involved in intracellular septation
F3X89_14605	COG0552	protein localization to endoplasmic reticulum
F3X89_14610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F3X89_14615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F3X89_14640	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3X89_14645	COG0287	Prephenate dehydrogenase
F3X89_14645	COG1605	Chorismate mutase
F3X89_14650	COG0228	four-way junction DNA binding
F3X89_14655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F3X89_14660	COG0336	Belongs to the RNA methyltransferase TrmD family
F3X89_14695	COG1522	sequence-specific DNA binding
F3X89_14705	COG0110	maltose O-acetyltransferase activity
F3X89_14710	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
F3X89_14715	COG0335	large ribosomal subunit rRNA binding
F3X89_14725	COG0765	amino acid transport
F3X89_14730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F3X89_14735	COG0697	spore germination
F3X89_14740	COG1846	Transcriptional regulator
F3X89_14760	COG0656	L-ascorbic acid biosynthetic process
F3X89_14770	COG0745	RESPONSE REGULATOR receiver
F3X89_14785	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3X89_14790	COG1674	ftsk spoiiie
F3X89_14795	COG0004	ammonium transporteR
F3X89_14800	COG0347	Belongs to the P(II) protein family
F3X89_14805	COG1946	Acyl-CoA thioesterase
F3X89_14810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3X89_14815	COG1733	regulation of RNA biosynthetic process
F3X89_14825	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_14830	COG2835	tetraacyldisaccharide 4'-kinase activity
F3X89_14840	COG3118	belongs to the thioredoxin family
F3X89_14865	COG0395	ABC-type sugar transport system, permease component
F3X89_14870	COG1175	transmembrane transport
F3X89_14880	COG3250	beta-galactosidase activity
F3X89_14885	COG1609	Transcriptional regulator
F3X89_14900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_14905	COG0745	RESPONSE REGULATOR receiver
F3X89_14910	COG2205	protein histidine kinase activity
F3X89_14965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3X89_14970	COG2076	Multidrug Resistance protein
F3X89_14980	COG1647	Serine aminopeptidase, S33
F3X89_14990	COG2076	Multidrug Resistance protein
F3X89_15000	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_15005	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
F3X89_15020	COG3618	amidohydrolase
F3X89_15025	COG2814	Major facilitator Superfamily
F3X89_15030	COG2188	Transcriptional regulator
F3X89_15035	COG0583	DNA-binding transcription factor activity
F3X89_15045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3X89_15050	COG0697	spore germination
F3X89_15060	COG1309	transcriptional regulator
F3X89_15080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
F3X89_15095	COG0438	transferase activity, transferring glycosyl groups
F3X89_15130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_15135	COG1116	anion transmembrane transporter activity
F3X89_15140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_15150	COG1396	sequence-specific DNA binding
F3X89_15185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_15190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_15200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_15250	COG2814	Major facilitator Superfamily
F3X89_15255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
F3X89_15270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F3X89_15275	COG2986	histidine ammonia-lyase
F3X89_15280	COG1228	amidohydrolase
F3X89_15285	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_15290	COG2188	Transcriptional regulator
F3X89_15300	COG2986	histidine ammonia-lyase
F3X89_15320	COG0025	NhaP-type Na H and K H
F3X89_15345	COG1321	iron dependent repressor
F3X89_15350	COG1914	H( )-stimulated, divalent metal cation uptake system
F3X89_15355	COG0739	heme binding
F3X89_15370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_15375	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3X89_15380	COG2080	2 iron, 2 sulfur cluster binding
F3X89_15385	COG1309	transcriptional regulator
F3X89_15395	COG3842	ATPase activity
F3X89_15400	COG0395	ABC-type sugar transport system, permease component
F3X89_15405	COG1175	transmembrane transport
F3X89_15445	COG3842	ATPase activity
F3X89_15455	COG0395	ABC-type sugar transport system, permease component
F3X89_15470	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
F3X89_15475	COG2182	Extracellular solute-binding protein
F3X89_15490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_15500	COG0673	inositol 2-dehydrogenase activity
F3X89_15510	COG0673	inositol 2-dehydrogenase activity
F3X89_15515	COG1309	transcriptional regulator
F3X89_15525	COG1175	transmembrane transport
F3X89_15530	COG0395	ABC-type sugar transport system, permease component
F3X89_15535	COG0673	inositol 2-dehydrogenase activity
F3X89_15540	COG0673	inositol 2-dehydrogenase activity
F3X89_15560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F3X89_15570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_15575	COG1509	lysine 2,3-aminomutase activity
F3X89_15580	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F3X89_15585	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F3X89_15605	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
F3X89_15630	COG2188	Transcriptional regulator
F3X89_15635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3X89_15640	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F3X89_15655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_15660	COG0488	(ABC) transporter
F3X89_15675	COG0477	Major facilitator Superfamily
F3X89_15690	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
F3X89_15705	COG1329	Transcriptional regulator
F3X89_15710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3X89_15740	COG0183	Belongs to the thiolase family
F3X89_15745	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
F3X89_15750	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F3X89_15760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3X89_15765	COG0142	geranyltranstransferase activity
F3X89_15775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F3X89_15780	COG2223	nitrite transmembrane transporter activity
F3X89_15785	COG0697	spore germination
F3X89_15800	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_15805	COG0583	DNA-binding transcription factor activity
F3X89_15810	COG0662	Cupin 2, conserved barrel domain protein
F3X89_15825	COG0740	serine-type endopeptidase activity
F3X89_15830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_15835	COG0765	amino acid transport
F3X89_15840	COG1126	abc transporter atp-binding protein
F3X89_15850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_15855	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3X89_15865	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
F3X89_15875	COG1132	(ABC) transporter
F3X89_15890	COG3459	Glycosyltransferase 36 associated
F3X89_15910	COG0444	Belongs to the ABC transporter superfamily
F3X89_15915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_15920	COG0601	transmembrane transport
F3X89_15935	COG1280	lysine exporter protein (LysE YggA)
F3X89_15940	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
F3X89_15940	COG4447	cellulose binding
F3X89_15995	COG3550	peptidyl-serine autophosphorylation
F3X89_16060	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_16065	COG1129	ABC transporter
F3X89_16115	COG3038	cytochrome b561
F3X89_16130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3X89_16140	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F3X89_16145	COG2948	multi-organism process
F3X89_16150	COG3504	Conjugal transfer protein
F3X89_16155	COG3736	Type IV secretory pathway, component VirB8
F3X89_16165	COG3704	protein secretion by the type IV secretion system
F3X89_16180	COG3451	type IV secretory pathway VirB4
F3X89_16185	COG3702	type iv secretory pathway
F3X89_16190	COG3838	Conjugal transfer protein Trbc
F3X89_16235	COG1396	sequence-specific DNA binding
F3X89_16240	COG1476	TRANSCRIPTIONal
F3X89_16245	COG1396	sequence-specific DNA binding
F3X89_16290	COG3505	Type IV secretory pathway VirD4
F3X89_16295	COG0438	transferase activity, transferring glycosyl groups
F3X89_16300	COG0438	transferase activity, transferring glycosyl groups
F3X89_16325	COG0662	Cupin 2, conserved barrel domain protein
F3X89_16325	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
F3X89_16350	COG1216	Glycosyl transferase, family 2
F3X89_16350	COG0438	transferase activity, transferring glycosyl groups
F3X89_16415	COG3220	belongs to the UPF0276 family
F3X89_16455	COG4650	regulator
F3X89_16465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
F3X89_16470	COG0211	Belongs to the bacterial ribosomal protein bL27 family
F3X89_16485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F3X89_16490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F3X89_16495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F3X89_16500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F3X89_16505	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3X89_16510	COG4149	molybdate abc transporter
F3X89_16515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F3X89_16520	COG2005	Transcriptional regulator
F3X89_16520	COG3585	molybdate ion transport
F3X89_16525	COG0799	negative regulation of ribosome biogenesis
F3X89_16530	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
F3X89_16540	COG0793	Belongs to the peptidase S41A family
F3X89_16550	COG0494	nUDIX hydrolase
F3X89_16565	COG0587	DNA-directed DNA polymerase activity
F3X89_16590	COG2301	Belongs to the HpcH HpaI aldolase family
F3X89_16600	COG0066	3-isopropylmalate dehydratase activity
F3X89_16610	COG0473	3-isopropylmalate dehydrogenase activity
F3X89_16615	COG0671	phosphoesterase, PA-phosphatase related
F3X89_16625	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_16630	COG0783	Belongs to the Dps family
F3X89_16635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F3X89_16645	COG0288	reversible hydration of carbon dioxide
F3X89_16655	COG2902	Dehydrogenase
F3X89_16660	COG2270	Major facilitator Superfamily
F3X89_16665	COG0138	bifunctional purine biosynthesis protein purh
F3X89_16675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F3X89_16675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F3X89_16680	COG0501	Belongs to the peptidase M48B family
F3X89_16690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_16705	COG0495	leucyl-tRNA aminoacylation
F3X89_16730	COG0357	Ribosomal RNA small subunit methyltransferase G
F3X89_16735	COG0445	tRNA wobble uridine modification
F3X89_16740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F3X89_16745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F3X89_16750	COG1981	membrane
F3X89_16755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F3X89_16760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F3X89_16765	COG0424	maF-like protein
F3X89_16770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3X89_16775	COG0237	dephospho-CoA kinase activity
F3X89_16790	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F3X89_16805	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F3X89_16860	COG0135	phosphoribosylanthranilate isomerase activity
F3X89_16865	COG0133	tryptophan synthase activity
F3X89_16870	COG0159	tryptophan synthase activity
F3X89_16875	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F3X89_16890	COG1074	ATP-dependent DNA helicase activity
F3X89_16900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3X89_16905	COG3178	'Phosphotransferase
F3X89_16910	COG2205	protein histidine kinase activity
F3X89_16915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3X89_16920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_16925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_16925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F3X89_16935	COG0642	Histidine kinase
F3X89_16940	COG0745	RESPONSE REGULATOR receiver
F3X89_16945	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F3X89_16965	COG1072	(Pantothenic acid kinase))
F3X89_16970	COG0140	phosphoribosyl-ATP diphosphatase activity
F3X89_16975	COG0107	imidazoleglycerol-phosphate synthase activity
F3X89_16980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F3X89_16985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3X89_16995	COG0131	Imidazoleglycerol-phosphate dehydratase
F3X89_17000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F3X89_17005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F3X89_17025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3X89_17040	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
F3X89_17050	COG1643	Atp-dependent helicase
F3X89_17055	COG2423	ornithine cyclodeaminase activity
F3X89_17160	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_17165	COG0673	inositol 2-dehydrogenase activity
F3X89_17170	COG3962	Belongs to the TPP enzyme family
F3X89_17190	COG0673	inositol 2-dehydrogenase activity
F3X89_17205	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_17210	COG1129	ABC transporter
F3X89_17220	COG0673	inositol 2-dehydrogenase activity
F3X89_17225	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_17255	COG0395	ABC-type sugar transport system, permease component
F3X89_17275	COG3622	Belongs to the hyi family
F3X89_17280	COG1276	copper resistance
F3X89_17285	COG2372	response to copper ion
F3X89_17290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3X89_17295	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_17300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3X89_17320	COG0539	negative regulation of cytoplasmic translation
F3X89_17325	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F3X89_17330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F3X89_17345	COG2815	serine threonine protein kinase
F3X89_17345	COG0515	serine threonine protein kinase
F3X89_17350	COG0631	protein serine/threonine phosphatase activity
F3X89_17465	COG2860	membrane
F3X89_17475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F3X89_17485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F3X89_17490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_17505	COG1185	polyribonucleotide nucleotidyltransferase activity
F3X89_17510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
F3X89_17515	COG2267	carboxylic ester hydrolase activity
F3X89_17520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F3X89_17525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F3X89_17530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F3X89_17545	COG0779	Required for maturation of 30S ribosomal subunits
F3X89_17550	COG2951	lytic endotransglycosylase activity
F3X89_17555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F3X89_17570	COG1522	sequence-specific DNA binding
F3X89_17575	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F3X89_17580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3X89_17595	COG2816	NAD+ diphosphatase activity
F3X89_17600	COG2378	regulation of single-species biofilm formation
F3X89_17615	COG1605	Chorismate mutase
F3X89_17615	COG0077	Prephenate dehydratase
F3X89_17620	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
F3X89_17625	COG3474	cytochrome
F3X89_17640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_17660	COG2226	methyltransferase
F3X89_17675	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F3X89_17680	COG0484	heat shock protein binding
F3X89_17685	COG0443	Heat shock 70 kDa protein
F3X89_17690	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F3X89_17715	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F3X89_17725	COG1187	pseudouridine synthase activity
F3X89_17735	COG2205	protein histidine kinase activity
F3X89_17775	COG0840	transmembrane signaling receptor activity
F3X89_17775	COG2972	Histidine kinase
F3X89_17780	COG3842	ATPase activity
F3X89_17790	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_17800	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_17810	COG2200	EAL domain
F3X89_17810	COG2199	diguanylate cyclase activity
F3X89_17820	COG4957	zinc ion binding
F3X89_17825	COG0306	phosphate transporter
F3X89_17860	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3X89_17865	COG1845	cytochrome c oxidase, subunit III
F3X89_17870	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3X89_17875	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3X89_17880	COG0477	Major facilitator Superfamily
F3X89_17895	COG3842	ATPase activity
F3X89_17900	COG1473	amidohydrolase
F3X89_17905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_17915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_17920	COG3300	MHYT domain
F3X89_17920	COG5001	Diguanylate cyclase
F3X89_17930	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3X89_17930	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F3X89_17935	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3X89_17940	COG3454	Phosphonate metabolism
F3X89_17945	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F3X89_17950	COG3639	organic phosphonate transmembrane transporter activity
F3X89_17965	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
F3X89_17980	COG4778	phosphonate C-P lyase system protein PhnL
F3X89_17985	COG4107	phosphonate C-P lyase system protein PhnK
F3X89_17990	COG3627	carbon phosphorus lyase activity
F3X89_17995	COG3626	phosphonate metabolism
F3X89_18000	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F3X89_18005	COG3624	Phosphonate C-P lyase system protein PhnG
F3X89_18010	COG2188	Transcriptional regulator
F3X89_18015	COG0588	phosphoglycerate mutase activity
F3X89_18020	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F3X89_18025	COG1132	(ABC) transporter
F3X89_18030	COG0837	glucose binding
F3X89_18035	COG1803	Methylglyoxal synthase
F3X89_18040	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
F3X89_18050	COG4166	transmembrane transport
F3X89_18055	COG4174	ABC transporter (Permease)
F3X89_18060	COG4239	(ABC) transporter, permease
F3X89_18065	COG4172	Belongs to the ABC transporter superfamily
F3X89_18070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_18075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F3X89_18095	COG0668	transmembrane transport
F3X89_18110	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_18115	COG1902	pentaerythritol trinitrate reductase activity
F3X89_18120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3X89_18150	COG0583	DNA-binding transcription factor activity
F3X89_18160	COG2814	Major facilitator Superfamily
F3X89_18170	COG0667	Aldo Keto reductase
F3X89_18175	COG0583	DNA-binding transcription factor activity
F3X89_18200	COG1744	ABC transporter substrate-binding protein PnrA-like
F3X89_18205	COG3845	ABC transporter
F3X89_18210	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3X89_18215	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_18225	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
F3X89_18230	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F3X89_18235	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F3X89_18245	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F3X89_18250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F3X89_18255	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F3X89_18295	COG4964	Belongs to the GSP D family
F3X89_18335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F3X89_18355	COG0154	amidase activity
F3X89_18360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_18370	COG0747	negative chemotaxis
F3X89_18390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3X89_18395	COG3038	cytochrome b561
F3X89_18410	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
F3X89_18435	COG0673	inositol 2-dehydrogenase activity
F3X89_18445	COG0395	ABC-type sugar transport system, permease component
F3X89_18455	COG3842	ATPase activity
F3X89_18480	COG1737	Transcriptional regulator
F3X89_18515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3X89_18530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3X89_18540	COG0481	GTPase activity
F3X89_18565	COG5006	permease, DMT superfamily
F3X89_18590	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F3X89_18595	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F3X89_18600	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F3X89_18610	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
F3X89_18615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3X89_18615	COG0072	phenylalanine-tRNA ligase activity
F3X89_18625	COG4953	penicillin-binding protein 1C
F3X89_18635	COG0667	Aldo Keto reductase
F3X89_18640	COG0583	DNA-binding transcription factor activity
F3X89_18655	COG0667	Aldo Keto reductase
F3X89_18660	COG4977	sequence-specific DNA binding
F3X89_18695	COG1570	exodeoxyribonuclease VII activity
F3X89_18700	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3X89_18705	COG2309	aminopeptidase activity
F3X89_18725	COG1393	Belongs to the ArsC family
F3X89_18765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3X89_18775	COG0583	DNA-binding transcription factor activity
F3X89_18780	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3X89_18790	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_18800	COG3663	DNA glycosylase
F3X89_18825	COG0583	DNA-binding transcription factor activity
F3X89_18830	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_18840	COG2020	methyltransferase activity
F3X89_18855	COG1309	transcriptional regulator
F3X89_18860	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3X89_18860	COG0519	Catalyzes the synthesis of GMP from XMP
F3X89_18910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3X89_18920	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3X89_18930	COG1968	undecaprenyl-diphosphatase activity
F3X89_18950	COG0284	orotidine-5'-phosphate decarboxylase activity
F3X89_18960	COG3963	phosphatidate phosphatase activity
F3X89_18970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F3X89_18975	COG0792	nuclease activity
F3X89_18990	COG0189	ligase activity
F3X89_19005	COG1280	lysine exporter protein (LysE YggA)
F3X89_19010	COG1335	isochorismatase
F3X89_19015	COG1280	lysine exporter protein (LysE YggA)
F3X89_19035	COG1522	sequence-specific DNA binding
F3X89_19045	COG0756	dUTP diphosphatase activity
F3X89_19050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F3X89_19075	COG0667	Aldo Keto reductase
F3X89_19080	COG0583	DNA-binding transcription factor activity
F3X89_19085	COG1720	tRNA m6t6A37 methyltransferase activity
F3X89_19090	COG3585	molybdate ion transport
F3X89_19095	COG3119	arylsulfatase activity
F3X89_19100	COG0583	DNA-binding transcription factor activity
F3X89_19105	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F3X89_19110	COG1877	trehalose-phosphatase activity
F3X89_19120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3X89_19130	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_19135	COG0583	DNA-binding transcription factor activity
F3X89_19140	COG0583	DNA-binding transcription factor activity
F3X89_19145	COG2814	Major facilitator Superfamily
F3X89_19170	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F3X89_19190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F3X89_19195	COG2986	histidine ammonia-lyase
F3X89_19205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F3X89_19210	COG2226	methyltransferase
F3X89_19215	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F3X89_19220	COG1024	Enoyl-CoA hydratase
F3X89_19225	COG0268	Binds directly to 16S ribosomal RNA
F3X89_19230	COG1192	Involved in chromosome partitioning
F3X89_19235	COG1475	DNA binding
F3X89_19240	COG0640	Transcriptional regulator
F3X89_19255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_19265	COG0583	DNA-binding transcription factor activity
F3X89_19315	COG0745	RESPONSE REGULATOR receiver
F3X89_19325	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_19330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_19340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_19390	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_19400	COG0840	transmembrane signaling receptor activity
F3X89_19415	COG1902	pentaerythritol trinitrate reductase activity
F3X89_19420	COG0427	acetyl-CoA hydrolase
F3X89_19425	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_19435	COG4208	sulfate ABC transporter
F3X89_19440	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_19450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_19460	COG3842	ATPase activity
F3X89_19465	COG0583	DNA-binding transcription factor activity
F3X89_19470	COG1126	abc transporter atp-binding protein
F3X89_19475	COG0765	amino acid transport
F3X89_19480	COG0765	amino acid transport
F3X89_19495	COG0667	Aldo Keto reductase
F3X89_19500	COG0583	DNA-binding transcription factor activity
F3X89_19515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3X89_19520	COG2267	carboxylic ester hydrolase activity
F3X89_19525	COG0251	oxidation-reduction process
F3X89_19530	COG1335	isochorismatase
F3X89_19535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_19540	COG5265	(ABC) transporter
F3X89_19555	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_19560	COG1940	carbohydrate kinase activity
F3X89_19560	COG1846	Transcriptional regulator
F3X89_19565	COG1082	Xylose isomerase domain protein TIM barrel
F3X89_19570	COG1917	Cupin 2, conserved barrel domain protein
F3X89_19570	COG2207	Transcriptional regulator
F3X89_19580	COG1175	transmembrane transport
F3X89_19595	COG1063	alcohol dehydrogenase
F3X89_19600	COG3842	ATPase activity
F3X89_19605	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_19625	COG0504	CTP synthase activity
F3X89_19630	COG0006	proline dipeptidase activity
F3X89_19635	COG4948	Mandelate Racemase Muconate Lactonizing
F3X89_19640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_19645	COG1126	abc transporter atp-binding protein
F3X89_19650	COG0765	amino acid transport
F3X89_19655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_19660	COG2186	Transcriptional regulator
F3X89_19665	COG1177	transmembrane transport
F3X89_19675	COG3842	ATPase activity
F3X89_19690	COG1024	Enoyl-CoA hydratase
F3X89_19700	COG0277	FAD linked oxidase domain protein
F3X89_19710	COG0604	alcohol dehydrogenase
F3X89_19715	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3X89_19720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_19745	COG1802	Transcriptional regulator
F3X89_19750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_19755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_19775	COG0765	amino acid transport
F3X89_19780	COG0765	amino acid transport
F3X89_19785	COG1126	abc transporter atp-binding protein
F3X89_19800	COG0444	Belongs to the ABC transporter superfamily
F3X89_19805	COG4608	Belongs to the ABC transporter superfamily
F3X89_19810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_19820	COG0747	negative chemotaxis
F3X89_19825	COG3257	ureidoglycine aminohydrolase activity
F3X89_19830	COG0583	DNA-binding transcription factor activity
F3X89_19835	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_19845	COG1335	isochorismatase
F3X89_19850	COG0583	DNA-binding transcription factor activity
F3X89_19855	COG0583	DNA-binding transcription factor activity
F3X89_19875	COG0697	spore germination
F3X89_19890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_19895	COG0683	leucine binding
F3X89_19910	COG0411	ABC transporter
F3X89_19925	COG1802	Transcriptional regulator
F3X89_19940	COG1126	abc transporter atp-binding protein
F3X89_19945	COG0765	amino acid transport
F3X89_19950	COG0765	amino acid transport
F3X89_19960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_19970	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_19975	COG2197	response regulator
F3X89_19980	COG0601	transmembrane transport
F3X89_19985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_20005	COG0747	negative chemotaxis
F3X89_20030	COG4191	Histidine kinase
F3X89_20030	COG0784	Response regulator, receiver
F3X89_20035	COG2197	response regulator
F3X89_20040	COG3237	CsbD-like
F3X89_20050	COG3920	Histidine kinase
F3X89_20075	COG0765	amino acid transport
F3X89_20080	COG4597	amino acid ABC transporter
F3X89_20085	COG4598	ABC transporter
F3X89_20100	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_20105	COG4603	Belongs to the binding-protein-dependent transport system permease family
F3X89_20110	COG3845	ABC transporter
F3X89_20125	COG0793	Belongs to the peptidase S41A family
F3X89_20130	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_20140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_20150	COG1177	transmembrane transport
F3X89_20155	COG3842	ATPase activity
F3X89_20165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_20170	COG0583	DNA-binding transcription factor activity
F3X89_20220	COG0583	DNA-binding transcription factor activity
F3X89_20230	COG0583	DNA-binding transcription factor activity
F3X89_20235	COG3384	dioxygenase
F3X89_20255	COG0025	NhaP-type Na H and K H
F3X89_20270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_20275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_20295	COG2022	thiamine diphosphate biosynthetic process
F3X89_20310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F3X89_20315	COG1609	Transcriptional regulator
F3X89_20325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_20330	COG0765	amino acid transport
F3X89_20335	COG0765	amino acid transport
F3X89_20345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3X89_20355	COG0583	DNA-binding transcription factor activity
F3X89_20370	COG0765	amino acid transport
F3X89_20375	COG1126	abc transporter atp-binding protein
F3X89_20380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_20385	COG1522	sequence-specific DNA binding
F3X89_20400	COG0667	Aldo Keto reductase
F3X89_20405	COG2814	Major facilitator Superfamily
F3X89_20415	COG0583	DNA-binding transcription factor activity
F3X89_20425	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_20430	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3X89_20435	COG2080	2 iron, 2 sulfur cluster binding
F3X89_20480	COG3153	acetyltransferase
F3X89_20505	COG0698	ribose 5-phosphate isomerase
F3X89_20510	COG0149	triose-phosphate isomerase activity
F3X89_20545	COG1129	ABC transporter
F3X89_20550	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_20555	COG1879	ABC-type sugar transport system periplasmic component
F3X89_20560	COG1349	DNA-binding transcription factor activity
F3X89_20570	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F3X89_20580	COG0511	ligase activity, forming carbon-carbon bonds
F3X89_20585	COG0439	Biotin carboxylase
F3X89_20595	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_20600	COG1984	allophanate hydrolase subunit 2
F3X89_20605	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_20610	COG0436	Aminotransferase
F3X89_20620	COG4221	oxidoreductase activity
F3X89_20625	COG0765	amino acid transport
F3X89_20630	COG0765	amino acid transport
F3X89_20645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_20655	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_20685	COG3842	ATPase activity
F3X89_20690	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_20705	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_20715	COG3842	ATPase activity
F3X89_20720	COG0726	polysaccharide deacetylase
F3X89_20730	COG0523	cobalamin synthesis protein
F3X89_20740	COG0154	amidase activity
F3X89_20745	COG2909	trisaccharide binding
F3X89_20760	COG3842	ATPase activity
F3X89_20770	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_20775	COG1177	transmembrane transport
F3X89_20780	COG1129	ABC transporter
F3X89_20785	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_20790	COG1879	ABC-type sugar transport system periplasmic component
F3X89_20795	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_20800	COG2376	Dihydroxyacetone kinase
F3X89_20810	COG2376	Dihydroxyacetone kinase
F3X89_20835	COG2207	Transcriptional regulator
F3X89_20840	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_20850	COG1335	isochorismatase
F3X89_20860	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_20940	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_20945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
F3X89_20950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3X89_20970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3X89_20975	COG4191	Histidine kinase
F3X89_20975	COG0784	Response regulator, receiver
F3X89_20985	COG1294	oxidase, subunit
F3X89_20990	COG1271	oxidase subunit
F3X89_20995	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F3X89_21000	COG4988	ABC transporter
F3X89_21010	COG0517	IMP dehydrogenase activity
F3X89_21010	COG0516	GMP reductase activity
F3X89_21045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_21050	COG3609	addiction module antidote protein, CC2985 family
F3X89_21055	COG3668	Plasmid stabilization system
F3X89_21095	COG2208	phosphoserine phosphatase activity
F3X89_21100	COG2226	methyltransferase
F3X89_21110	COG3300	MHYT domain
F3X89_21110	COG5001	Diguanylate cyclase
F3X89_21115	COG2205	protein histidine kinase activity
F3X89_21115	COG0745	RESPONSE REGULATOR receiver
F3X89_21115	COG3292	Two component regulator propeller
F3X89_21125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3X89_21135	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
F3X89_21180	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F3X89_21180	COG2273	Hydrolase Family 16
F3X89_21205	COG2197	response regulator
F3X89_21210	COG2890	protein-(glutamine-N5) methyltransferase activity
F3X89_21215	COG0367	asparagine synthase
F3X89_21225	COG0318	PFAM AMP-dependent synthetase and ligase
F3X89_21230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F3X89_21235	COG3321	synthase
F3X89_21235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3X89_21235	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3X89_21235	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3X89_21245	COG3300	MHYT domain
F3X89_21245	COG5001	Diguanylate cyclase
F3X89_21255	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F3X89_21285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_21290	COG1116	anion transmembrane transporter activity
F3X89_21295	COG4191	Histidine kinase
F3X89_21305	COG1609	Transcriptional regulator
F3X89_21310	COG2271	Major facilitator Superfamily
F3X89_21315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_21320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_21370	COG4774	siderophore transport
F3X89_21375	COG2814	Major facilitator Superfamily
F3X89_21390	COG1473	amidohydrolase
F3X89_21405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_21415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_21455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_21470	COG0667	Aldo Keto reductase
F3X89_21490	COG0747	negative chemotaxis
F3X89_21495	COG0583	DNA-binding transcription factor activity
F3X89_21500	COG0778	Nitroreductase
F3X89_21520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_21535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_21540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_21545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_21550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_21555	COG0454	-acetyltransferase
F3X89_21560	COG0747	negative chemotaxis
F3X89_21565	COG0747	negative chemotaxis
F3X89_21585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_21640	COG1653	transport
F3X89_21645	COG2188	Transcriptional regulator
F3X89_21665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_21670	COG0601	transmembrane transport
F3X89_21675	COG0747	negative chemotaxis
F3X89_21680	COG2186	Transcriptional regulator
F3X89_21685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_21690	COG0747	negative chemotaxis
F3X89_21695	COG0601	transmembrane transport
F3X89_21700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_21705	COG0444	Belongs to the ABC transporter superfamily
F3X89_21710	COG4608	Belongs to the ABC transporter superfamily
F3X89_21715	COG3609	addiction module antidote protein, CC2985 family
F3X89_21725	COG0483	inositol monophosphate 1-phosphatase activity
F3X89_21730	COG0584	glycerophosphoryl diester phosphodiesterase
F3X89_21735	COG1940	carbohydrate kinase activity
F3X89_21740	COG5001	Diguanylate cyclase
F3X89_21740	COG3300	MHYT domain
F3X89_21760	COG3755	Protein conserved in bacteria
F3X89_21775	COG0840	transmembrane signaling receptor activity
F3X89_21780	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_21785	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_21790	COG1129	ABC transporter
F3X89_21805	COG0477	Major facilitator Superfamily
F3X89_21810	COG1309	transcriptional regulator
F3X89_21815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F3X89_21835	COG3344	reverse transcriptase
F3X89_21855	COG1396	sequence-specific DNA binding
F3X89_21865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3X89_21890	COG3177	Filamentation induced by cAMP protein fic
F3X89_21920	COG1537	nuclear-transcribed mRNA catabolic process, no-go decay
F3X89_22020	COG4467	Involved in initiation control of chromosome replication
F3X89_22055	COG1802	Transcriptional regulator
F3X89_22060	COG3938	Belongs to the proline racemase family
F3X89_22080	COG1126	abc transporter atp-binding protein
F3X89_22085	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_22095	COG0673	inositol 2-dehydrogenase activity
F3X89_22100	COG0395	ABC-type sugar transport system, permease component
F3X89_22105	COG1175	transmembrane transport
F3X89_22115	COG1653	transport
F3X89_22120	COG1335	isochorismatase
F3X89_22145	COG1744	ABC transporter substrate-binding protein PnrA-like
F3X89_22150	COG3845	ABC transporter
F3X89_22160	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_22180	COG0583	DNA-binding transcription factor activity
F3X89_22195	COG2963	transposase activity
F3X89_22200	COG3436	PFAM IS66 Orf2 family protein
F3X89_22210	COG4974	Belongs to the 'phage' integrase family
F3X89_22215	COG0582	viral genome integration into host DNA
F3X89_22220	COG4974	Belongs to the 'phage' integrase family
F3X89_22235	COG1454	alcohol dehydrogenase
F3X89_22260	COG0583	DNA-binding transcription factor activity
F3X89_22275	COG2226	methyltransferase
F3X89_22310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F3X89_22350	COG2375	cellular response to nickel ion
F3X89_22350	COG1132	(ABC) transporter
F3X89_22360	COG4774	siderophore transport
F3X89_22365	COG1309	transcriptional regulator
F3X89_22375	COG1982	Orn Lys Arg decarboxylase major
F3X89_22390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3X89_22390	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F3X89_22395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3X89_22400	COG1169	isochorismate synthase
F3X89_22405	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3X89_22415	COG1169	isochorismate synthase
F3X89_22465	COG1335	isochorismatase
F3X89_22470	COG3845	ABC transporter
F3X89_22485	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_22520	COG2814	Major facilitator Superfamily
F3X89_22525	COG0656	L-ascorbic acid biosynthetic process
F3X89_22530	COG0667	Aldo Keto reductase
F3X89_22555	COG1073	alpha beta
F3X89_22605	COG0339	signal peptide processing
F3X89_22650	COG1396	sequence-specific DNA binding
F3X89_22740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_22750	COG0747	negative chemotaxis
F3X89_22755	COG1737	Transcriptional regulator
F3X89_22765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_22775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_22780	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F3X89_22785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_22800	COG1024	Enoyl-CoA hydratase
F3X89_22805	COG0583	DNA-binding transcription factor activity
F3X89_22810	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3X89_22820	COG0583	DNA-binding transcription factor activity
F3X89_22825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F3X89_22830	COG3842	ATPase activity
F3X89_22835	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_22840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3X89_22845	COG2072	flavoprotein involved in K transport
F3X89_22865	COG0402	S-adenosylhomocysteine deaminase activity
F3X89_22880	COG0583	DNA-binding transcription factor activity
F3X89_22885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_22900	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_22920	COG1846	Transcriptional regulator
F3X89_22940	COG5001	Diguanylate cyclase
F3X89_22940	COG3300	MHYT domain
F3X89_22965	COG0583	DNA-binding transcription factor activity
F3X89_22970	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_22975	COG3959	Transketolase, thiamine diphosphate binding domain
F3X89_22980	COG3958	Transketolase
F3X89_22985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3X89_22990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F3X89_22995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
F3X89_23000	COG1129	ABC transporter
F3X89_23005	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_23010	COG1879	ABC-type sugar transport system periplasmic component
F3X89_23015	COG3618	amidohydrolase
F3X89_23020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3X89_23025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3X89_23030	COG0583	DNA-binding transcription factor activity
F3X89_23060	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_23065	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_23070	COG4177	L-phenylalanine transmembrane transporter activity
F3X89_23075	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_23085	COG1137	ATPase activity
F3X89_23110	COG1024	Enoyl-CoA hydratase
F3X89_23205	COG1845	cytochrome c oxidase, subunit III
F3X89_23210	COG1845	cytochrome c oxidase, subunit III
F3X89_23215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3X89_23220	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3X89_23255	COG4221	oxidoreductase activity
F3X89_23260	COG1309	transcriptional regulator
F3X89_23270	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3X89_23280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3X89_23295	COG1349	DNA-binding transcription factor activity
F3X89_23310	COG2072	flavoprotein involved in K transport
F3X89_23335	COG1335	isochorismatase
F3X89_23350	COG0434	BtpA family
F3X89_23355	COG1070	Carbohydrate kinase
F3X89_23385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3X89_23390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_23405	COG1733	regulation of RNA biosynthetic process
F3X89_23435	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_23440	COG3321	synthase
F3X89_23440	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_23440	COG0604	alcohol dehydrogenase
F3X89_23450	COG1335	isochorismatase
F3X89_23460	COG0583	DNA-binding transcription factor activity
F3X89_23465	COG1741	Belongs to the pirin family
F3X89_23485	COG1228	amidohydrolase
F3X89_23500	COG2207	Transcriptional regulator
F3X89_23520	COG2814	Major facilitator Superfamily
F3X89_23530	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_23535	COG2072	flavoprotein involved in K transport
F3X89_23555	COG1472	Belongs to the glycosyl hydrolase 3 family
F3X89_23570	COG0395	ABC-type sugar transport system, permease component
F3X89_23575	COG1175	transmembrane transport
F3X89_23580	COG1653	transport
F3X89_23610	COG0601	transmembrane transport
F3X89_23620	COG4608	Belongs to the ABC transporter superfamily
F3X89_23630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_23695	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_23710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_23715	COG0159	tryptophan synthase activity
F3X89_23725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_23730	COG3842	ATPase activity
F3X89_23735	COG3833	ABC-type maltose transport systems, permease component
F3X89_23740	COG1175	transmembrane transport
F3X89_23755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_23765	COG1595	DNA-templated transcription, initiation
F3X89_23800	COG0444	Belongs to the ABC transporter superfamily
F3X89_23805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_23820	COG0747	negative chemotaxis
F3X89_23825	COG2186	Transcriptional regulator
F3X89_23850	COG3842	ATPase activity
F3X89_23885	COG2272	Belongs to the type-B carboxylesterase lipase family
F3X89_23900	COG2211	Major facilitator Superfamily
F3X89_23920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3X89_23930	COG1280	lysine exporter protein (LysE YggA)
F3X89_23935	COG2197	response regulator
F3X89_23945	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F3X89_23950	COG0720	synthase
F3X89_23955	COG0602	queuosine metabolic process
F3X89_23970	COG2267	carboxylic ester hydrolase activity
F3X89_23980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_23985	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_24005	COG1177	transmembrane transport
F3X89_24010	COG3842	ATPase activity
F3X89_24025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_24040	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_24050	COG0410	ABC transporter
F3X89_24060	COG2706	6-phosphogluconolactonase activity
F3X89_24065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_24070	COG1312	Catalyzes the dehydration of D-mannonate
F3X89_24075	COG2186	Transcriptional regulator
F3X89_24085	COG0601	transmembrane transport
F3X89_24090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_24145	COG4774	siderophore transport
F3X89_24160	COG1473	amidohydrolase
F3X89_24165	COG0747	negative chemotaxis
F3X89_24170	COG0601	transmembrane transport
F3X89_24175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_24180	COG4172	Belongs to the ABC transporter superfamily
F3X89_24190	COG3386	PFAM SMP-30 Gluconolaconase
F3X89_24200	COG1063	alcohol dehydrogenase
F3X89_24205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3X89_24210	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_24215	COG2084	Dehydrogenase
F3X89_24225	COG1609	Transcriptional regulator
F3X89_24235	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_24240	COG1129	ABC transporter
F3X89_24250	COG0840	transmembrane signaling receptor activity
F3X89_24270	COG4214	carbohydrate transport
F3X89_24280	COG1070	Carbohydrate kinase
F3X89_24285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_24290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_24295	COG0601	transmembrane transport
F3X89_24320	COG4172	Belongs to the ABC transporter superfamily
F3X89_24325	COG3842	ATPase activity
F3X89_24335	COG0516	GMP reductase activity
F3X89_24350	COG0673	inositol 2-dehydrogenase activity
F3X89_24360	COG0395	ABC-type sugar transport system, permease component
F3X89_24375	COG0673	inositol 2-dehydrogenase activity
F3X89_24390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_24395	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
F3X89_24400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3X89_24405	COG2390	Transcriptional regulator
F3X89_24415	COG1940	carbohydrate kinase activity
F3X89_24420	COG1879	ABC-type sugar transport system periplasmic component
F3X89_24450	COG0765	amino acid transport
F3X89_24455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_24465	COG1126	abc transporter atp-binding protein
F3X89_24485	COG1522	sequence-specific DNA binding
F3X89_24540	COG0864	Transcriptional regulator
F3X89_24550	COG1609	Transcriptional regulator
F3X89_24575	COG0697	spore germination
F3X89_24580	COG3206	protein involved in exopolysaccharide biosynthesis
F3X89_24580	COG0489	protein tyrosine kinase activity
F3X89_24585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3X89_24590	COG1215	transferase activity, transferring glycosyl groups
F3X89_24595	COG1215	transferase activity, transferring glycosyl groups
F3X89_24600	COG1215	transferase activity, transferring glycosyl groups
F3X89_24605	COG0438	transferase activity, transferring glycosyl groups
F3X89_24610	COG2273	Hydrolase Family 16
F3X89_24615	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_24620	COG2244	polysaccharide biosynthetic process
F3X89_24625	COG0463	Glycosyl transferase, family 2
F3X89_24630	COG2327	Polysaccharide pyruvyl transferase
F3X89_24635	COG1215	transferase activity, transferring glycosyl groups
F3X89_24650	COG1596	polysaccharide export
F3X89_24655	COG3307	-O-antigen
F3X89_24660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_24670	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_24690	COG2721	sulfolactate sulfo-lyase activity
F3X89_24705	COG2207	Transcriptional regulator
F3X89_24710	COG1486	melibiose metabolic process
F3X89_24715	COG0747	negative chemotaxis
F3X89_24720	COG0601	transmembrane transport
F3X89_24725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_24730	COG4172	Belongs to the ABC transporter superfamily
F3X89_24735	COG1486	melibiose metabolic process
F3X89_24755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3X89_24755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3X89_24760	COG1132	(ABC) transporter
F3X89_24780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_24790	COG0747	negative chemotaxis
F3X89_24820	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
F3X89_24835	COG1234	tRNA 3'-trailer cleavage
F3X89_24860	COG0559	Belongs to the binding-protein-dependent transport system permease family
F3X89_24870	COG0683	leucine binding
F3X89_24880	COG3485	protocatechuate 3,4-dioxygenase
F3X89_24885	COG3485	protocatechuate 3,4-dioxygenase
F3X89_24890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3X89_24895	COG2267	carboxylic ester hydrolase activity
F3X89_24900	COG0583	DNA-binding transcription factor activity
F3X89_24915	COG1414	Transcriptional regulator
F3X89_24925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3X89_24935	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_24965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3X89_24980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3X89_24985	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3X89_24990	COG4208	sulfate ABC transporter
F3X89_25000	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3X89_25005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3X89_25015	COG2205	protein histidine kinase activity
F3X89_25020	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F3X89_25025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F3X89_25030	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F3X89_25065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_25070	COG0444	Belongs to the ABC transporter superfamily
F3X89_25075	COG4608	Belongs to the ABC transporter superfamily
F3X89_25090	COG2197	response regulator
F3X89_25095	COG0784	Response regulator, receiver
F3X89_25095	COG2205	protein histidine kinase activity
F3X89_25110	COG0235	Class ii aldolase
F3X89_25115	COG3395	kinase activity
F3X89_25120	COG3622	Belongs to the hyi family
F3X89_25125	COG2084	Dehydrogenase
F3X89_25135	COG1609	Transcriptional regulator
F3X89_25145	COG0765	amino acid transport
F3X89_25150	COG0765	amino acid transport
F3X89_25160	COG0251	oxidation-reduction process
F3X89_25175	COG0235	Class ii aldolase
F3X89_25185	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_25190	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_25195	COG1129	ABC transporter
F3X89_25205	COG1609	Transcriptional regulator
F3X89_25225	COG1215	transferase activity, transferring glycosyl groups
F3X89_25265	COG1278	Cold shock
F3X89_25280	COG0659	secondary active sulfate transmembrane transporter activity
F3X89_25310	COG2205	protein histidine kinase activity
F3X89_25315	COG1396	sequence-specific DNA binding
F3X89_25350	COG1596	polysaccharide export
F3X89_25355	COG0438	transferase activity, transferring glycosyl groups
F3X89_25390	COG1215	transferase activity, transferring glycosyl groups
F3X89_25430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
F3X89_25455	COG0583	DNA-binding transcription factor activity
F3X89_25460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_25465	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_25470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_25505	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_25515	COG1473	amidohydrolase
F3X89_25530	COG0601	transmembrane transport
F3X89_25545	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3X89_25560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
F3X89_25570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_25575	COG0601	transmembrane transport
F3X89_25580	COG0747	negative chemotaxis
F3X89_25585	COG0306	phosphate transporter
F3X89_25590	COG1392	Phosphate transport regulator
F3X89_25595	COG3842	ATPase activity
F3X89_25600	COG0395	ABC-type sugar transport system, permease component
F3X89_25605	COG1175	transmembrane transport
F3X89_25610	COG1653	transport
F3X89_25615	COG0697	spore germination
F3X89_25640	COG0747	negative chemotaxis
F3X89_25650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_25660	COG1733	regulation of RNA biosynthetic process
F3X89_25670	COG1132	(ABC) transporter
F3X89_25675	COG0463	Glycosyl transferase, family 2
F3X89_25680	COG1216	Glycosyl transferase, family 2
F3X89_25685	COG2755	lipolytic protein G-D-S-L family
F3X89_25685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
F3X89_25695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_25700	COG2079	MmgE PrpD family protein
F3X89_25705	COG1126	abc transporter atp-binding protein
F3X89_25710	COG0765	amino acid transport
F3X89_25735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_25740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_25745	COG1120	ATPase activity
F3X89_25755	COG5001	Diguanylate cyclase
F3X89_25755	COG3300	MHYT domain
F3X89_25775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_25780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3X89_25790	COG0583	DNA-binding transcription factor activity
F3X89_25805	COG0657	acetylesterase activity
F3X89_25815	COG4166	transmembrane transport
F3X89_25830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_25835	COG0601	transmembrane transport
F3X89_25840	COG0747	negative chemotaxis
F3X89_25860	COG3246	L-lysine catabolic process to acetate
F3X89_25870	COG0583	DNA-binding transcription factor activity
F3X89_25880	COG1609	Transcriptional regulator
F3X89_25885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_25890	COG1126	abc transporter atp-binding protein
F3X89_25895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_25915	COG3842	ATPase activity
F3X89_25925	COG0395	ABC-type sugar transport system, permease component
F3X89_25940	COG1461	Dihydroxyacetone kinase
F3X89_25945	COG2376	Dihydroxyacetone kinase
F3X89_25955	COG0673	inositol 2-dehydrogenase activity
F3X89_25960	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_25965	COG1129	ABC transporter
F3X89_25975	COG1879	ABC-type sugar transport system periplasmic component
F3X89_25980	COG0287	Prephenate dehydrogenase
F3X89_25990	COG1850	ribulose-bisphosphate carboxylase activity
F3X89_25995	COG2186	Transcriptional regulator
F3X89_26005	COG1968	undecaprenyl-diphosphatase activity
F3X89_26010	COG2824	Alkylphosphonate utilization operon protein PhnA
F3X89_26025	COG0352	thiamine-phosphate diphosphorylase activity
F3X89_26030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
F3X89_26045	COG0625	glutathione transferase activity
F3X89_26060	COG2204	response regulator
F3X89_26065	COG4191	Histidine kinase
F3X89_26070	COG1301	dicarboxylic acid transport
F3X89_26075	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
F3X89_26080	COG0577	efflux transmembrane transporter activity
F3X89_26080	COG1136	(ABC) transporter
F3X89_26090	COG1136	(ABC) transporter
F3X89_26100	COG2169	Transcriptional regulator
F3X89_26105	COG1414	Transcriptional regulator
F3X89_26115	COG0747	negative chemotaxis
F3X89_26135	COG4774	siderophore transport
F3X89_26145	COG2819	hydrolase of the alpha beta superfamily
F3X89_26150	COG1120	ATPase activity
F3X89_26155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3X89_26165	COG1522	sequence-specific DNA binding
F3X89_26170	COG4172	Belongs to the ABC transporter superfamily
F3X89_26175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_26180	COG0601	transmembrane transport
F3X89_26210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_26215	COG0251	oxidation-reduction process
F3X89_26235	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_26245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_26250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_26260	COG0454	-acetyltransferase
F3X89_26275	COG1414	Transcriptional regulator
F3X89_26285	COG3547	Transposase (IS116 IS110 IS902 family)
F3X89_26295	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F3X89_26385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F3X89_26410	COG1136	(ABC) transporter
F3X89_26410	COG0577	efflux transmembrane transporter activity
F3X89_26415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_26430	COG0436	Aminotransferase
F3X89_26440	COG0583	DNA-binding transcription factor activity
F3X89_26455	COG0765	amino acid transport
F3X89_26460	COG0765	amino acid transport
F3X89_26465	COG1126	abc transporter atp-binding protein
F3X89_26485	COG2197	response regulator
F3X89_26490	COG4585	Histidine kinase
F3X89_26500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3X89_26510	COG0006	proline dipeptidase activity
F3X89_26515	COG3842	ATPase activity
F3X89_26520	COG0395	ABC-type sugar transport system, permease component
F3X89_26535	COG0626	cystathionine gamma-synthase activity
F3X89_26540	COG2186	Transcriptional regulator
F3X89_26550	COG0657	acetylesterase activity
F3X89_26550	COG2755	lipolytic protein G-D-S-L family
F3X89_26570	COG3842	ATPase activity
F3X89_26580	COG1176	ABC-type spermidine putrescine transport system, permease component I
F3X89_26585	COG0395	ABC-type sugar transport system, permease component
F3X89_26600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_26605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_26610	COG1473	amidohydrolase
F3X89_26620	COG1126	abc transporter atp-binding protein
F3X89_26625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_26635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3X89_26640	COG1215	transferase activity, transferring glycosyl groups
F3X89_26650	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_26655	COG1129	ABC transporter
F3X89_26660	COG4213	ABC transporter substrate-binding protein
F3X89_26675	COG4993	Dehydrogenase
F3X89_26695	COG1846	Transcriptional regulator
F3X89_26695	COG1940	carbohydrate kinase activity
F3X89_26710	COG0395	ABC-type sugar transport system, permease component
F3X89_26770	COG0277	FAD linked oxidase domain protein
F3X89_26800	COG3344	reverse transcriptase
F3X89_26815	COG1902	pentaerythritol trinitrate reductase activity
F3X89_26820	COG4221	oxidoreductase activity
F3X89_26860	COG0667	Aldo Keto reductase
F3X89_26875	COG1902	pentaerythritol trinitrate reductase activity
F3X89_26875	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3X89_26885	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3X89_26895	COG4176	ABC-type proline glycine betaine transport system permease component
F3X89_26900	COG4175	Glycine betaine
F3X89_26900	COG0517	IMP dehydrogenase activity
F3X89_26905	COG1278	Cold shock
F3X89_26910	COG5342	invasion associated locus B
F3X89_26950	COG1349	DNA-binding transcription factor activity
F3X89_26960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3X89_26975	COG1175	transmembrane transport
F3X89_26980	COG0395	ABC-type sugar transport system, permease component
F3X89_26985	COG2204	response regulator
F3X89_26990	COG4191	Histidine kinase
F3X89_26995	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3X89_27005	COG1609	Transcriptional regulator
F3X89_27015	COG1175	transmembrane transport
F3X89_27020	COG0395	ABC-type sugar transport system, permease component
F3X89_27040	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3X89_27045	COG0625	glutathione transferase activity
F3X89_27065	COG3845	ABC transporter
F3X89_27075	COG1079	Belongs to the binding-protein-dependent transport system permease family
F3X89_27090	COG0243	molybdopterin cofactor binding
F3X89_27100	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F3X89_27105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3X89_27115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_27120	COG0601	transmembrane transport
F3X89_27125	COG0747	negative chemotaxis
F3X89_27130	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F3X89_27135	COG2971	BadF BadG BcrA BcrD
F3X89_27140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3X89_27145	COG1737	Transcriptional regulator
F3X89_27150	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_27160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F3X89_27165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F3X89_27190	COG1116	anion transmembrane transporter activity
F3X89_27195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3X89_27205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3X89_27210	COG0747	negative chemotaxis
F3X89_27215	COG4608	Belongs to the ABC transporter superfamily
F3X89_27235	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_27240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_27245	COG0601	transmembrane transport
F3X89_27255	COG0584	glycerophosphoryl diester phosphodiesterase
F3X89_27260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_27270	COG4172	Belongs to the ABC transporter superfamily
F3X89_27285	COG1609	Transcriptional regulator
F3X89_27300	COG2137	regulation of response to DNA damage stimulus
F3X89_27305	COG1802	Transcriptional regulator
F3X89_27310	COG1126	abc transporter atp-binding protein
F3X89_27315	COG0765	amino acid transport
F3X89_27320	COG0765	amino acid transport
F3X89_27330	COG1063	alcohol dehydrogenase
F3X89_27335	COG0246	Mannitol dehydrogenase
F3X89_27340	COG1312	Catalyzes the dehydration of D-mannonate
F3X89_27345	COG1802	Transcriptional regulator
F3X89_27350	COG0667	Aldo Keto reductase
F3X89_27360	COG1473	amidohydrolase
F3X89_27385	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
F3X89_27390	COG0667	Aldo Keto reductase
F3X89_27395	COG0583	DNA-binding transcription factor activity
F3X89_27400	COG0450	alkyl hydroperoxide reductase
F3X89_27415	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
F3X89_27415	COG2273	Hydrolase Family 16
F3X89_27420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3X89_27425	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
F3X89_27430	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F3X89_27435	COG2894	cell division
F3X89_27440	COG0850	regulation of cytokinetic process
F3X89_27445	COG0668	transmembrane transport
F3X89_27455	COG0252	asparaginase activity
F3X89_27465	COG1027	Aspartate ammonia-lyase
F3X89_27470	COG2186	Transcriptional regulator
F3X89_27500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_27505	COG4172	Belongs to the ABC transporter superfamily
F3X89_27510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_27525	COG1802	Transcriptional regulator
F3X89_27530	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F3X89_27535	COG1522	sequence-specific DNA binding
F3X89_27545	COG0318	PFAM AMP-dependent synthetase and ligase
F3X89_27560	COG1802	Transcriptional regulator
F3X89_27565	COG1984	allophanate hydrolase subunit 2
F3X89_27570	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_27575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F3X89_27590	COG0765	amino acid transport
F3X89_27595	COG0765	amino acid transport
F3X89_27605	COG0010	Belongs to the arginase family
F3X89_27625	COG2072	flavoprotein involved in K transport
F3X89_27630	COG1126	abc transporter atp-binding protein
F3X89_27635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3X89_27640	COG0765	amino acid transport
F3X89_27645	COG0765	amino acid transport
F3X89_27655	COG1921	L-seryl-tRNASec selenium transferase activity
F3X89_27670	COG3964	amidohydrolase
F3X89_27680	COG0601	transmembrane transport
F3X89_27685	COG0747	negative chemotaxis
F3X89_27710	COG0028	Belongs to the TPP enzyme family
F3X89_27715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3X89_27730	COG2837	iron assimilation
F3X89_27745	COG0542	response to heat
F3X89_27750	COG4191	Histidine kinase
F3X89_27765	COG0484	heat shock protein binding
F3X89_27775	COG0303	'Molybdopterin
F3X89_27780	COG0668	transmembrane transport
F3X89_27785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F3X89_27805	COG1294	oxidase, subunit
F3X89_27810	COG1271	oxidase subunit
F3X89_27815	COG0243	molybdopterin cofactor binding
F3X89_27820	COG3781	membrane
F3X89_27855	COG0300	oxidoreductase activity
F3X89_27880	COG0667	Aldo Keto reductase
F3X89_27890	COG1902	pentaerythritol trinitrate reductase activity
F3X89_27905	COG1840	ABC-type Fe3 transport system, periplasmic component
F3X89_27915	COG3842	ATPase activity
F3X89_27945	COG1215	transferase activity, transferring glycosyl groups
F3X89_27955	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F3X89_27965	COG3706	GGDEF domain
F3X89_27965	COG4251	negative regulation of phosphorylation
F3X89_27965	COG5001	Diguanylate cyclase
F3X89_27965	COG2203	Gaf domain
F3X89_27970	COG1609	Transcriptional regulator
F3X89_27980	COG1129	ABC transporter
F3X89_27985	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_28050	COG1459	type II secretion system
F3X89_28055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3X89_28080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3X89_28110	COG1376	ErfK ybiS ycfS ynhG family protein
F3X89_28125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3X89_28130	COG1473	amidohydrolase
F3X89_28155	COG0436	Aminotransferase
F3X89_28165	COG4302	ethanolamine ammonia-lyase activity
F3X89_28170	COG4303	Ethanolamine ammonia lyase large subunit
F3X89_28190	COG0235	Class ii aldolase
F3X89_28200	COG3239	Fatty acid desaturase
F3X89_28215	COG1116	anion transmembrane transporter activity
F3X89_28225	COG3665	Urea carboxylase-associated protein
F3X89_28230	COG4770	biotin carboxylase activity
F3X89_28240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3X89_28270	COG0596	Alpha beta hydrolase
F3X89_28385	COG0583	DNA-binding transcription factor activity
F3X89_28390	COG5383	Protein conserved in bacteria
F3X89_28395	COG1012	belongs to the aldehyde dehydrogenase family
F3X89_28400	COG0436	Aminotransferase
F3X89_28405	COG0247	lactate metabolic process
F3X89_28405	COG0277	FAD linked oxidase domain protein
F3X89_28415	COG1522	sequence-specific DNA binding
F3X89_28420	COG0154	amidase activity
F3X89_28425	COG1231	oxidoreductase activity
F3X89_28435	COG2222	sugar isomerase
F3X89_28440	COG1028	Short-chain dehydrogenase reductase Sdr
F3X89_28445	COG0006	proline dipeptidase activity
F3X89_28455	COG0667	Aldo Keto reductase
F3X89_28465	COG0300	oxidoreductase activity
F3X89_28485	COG0006	proline dipeptidase activity
F3X89_28490	COG3842	ATPase activity
F3X89_28505	COG0840	transmembrane signaling receptor activity
F3X89_28505	COG2972	Histidine kinase
F3X89_28525	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3X89_28530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
F3X89_28535	COG2080	2 iron, 2 sulfur cluster binding
F3X89_28540	COG2814	Major facilitator Superfamily
F3X89_28580	COG1064	alcohol dehydrogenase
F3X89_28590	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3X89_28595	COG0583	DNA-binding transcription factor activity
F3X89_28600	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
F3X89_28640	COG4302	ethanolamine ammonia-lyase activity
F3X89_28645	COG4303	Ethanolamine ammonia lyase large subunit
F3X89_28655	COG0154	amidase activity
F3X89_28670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_28675	COG4172	Belongs to the ABC transporter superfamily
F3X89_28680	COG1349	DNA-binding transcription factor activity
F3X89_28685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3X89_28705	COG1940	carbohydrate kinase activity
F3X89_28715	COG1879	ABC-type sugar transport system periplasmic component
F3X89_28725	COG1172	Belongs to the binding-protein-dependent transport system permease family
F3X89_28740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3X89_28750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3X89_28755	COG0563	adenylate kinase activity
F3X89_28760	COG2972	Histidine kinase
F3X89_28760	COG0840	transmembrane signaling receptor activity
F3X89_28770	COG0191	fructose-bisphosphate aldolase activity
F3X89_28775	COG0149	triose-phosphate isomerase activity
F3X89_28820	COG1475	DNA binding
F3X89_28860	COG4227	nucleotidyltransferase activity
F3X89_28865	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F3X89_28875	COG5489	Protein of unknown function (DUF736)
F3X89_28880	COG2161	toxin-antitoxin pair type II binding
F3X89_28900	COG5489	Protein of unknown function (DUF736)
F3X89_28905	COG3831	ATPase activity
F3X89_28915	COG1879	ABC-type sugar transport system periplasmic component
F3X89_28920	COG0840	transmembrane signaling receptor activity
F3X89_28930	COG3505	Type IV secretory pathway VirD4
F3X89_28945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3X89_28950	COG4959	Type IV secretory pathway protease TraF
F3X89_28955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3X89_28975	COG1476	TRANSCRIPTIONal
F3X89_28985	COG2771	luxR family
F3X89_28990	COG2948	multi-organism process
F3X89_29000	COG3504	Conjugal transfer protein
F3X89_29005	COG3701	Conjugal transfer protein
F3X89_29010	COG3846	protein secretion by the type IV secretion system
F3X89_29020	COG5314	conjugation
F3X89_29030	COG5268	conjugation
F3X89_29035	COG3838	Conjugal transfer protein Trbc
F3X89_29040	COG4962	Type ii secretion system protein e
F3X89_29045	COG3916	Acyl-homoserine-lactone synthase
F3X89_29050	COG1192	Involved in chromosome partitioning
F3X89_29055	COG1475	DNA binding
F3X89_29060	COG0640	Transcriptional regulator
F3X89_29065	COG2963	transposase activity
F3X89_29100	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F3X89_29215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
F3X89_29225	COG3436	PFAM IS66 Orf2 family protein
F3X89_29230	COG2963	transposase activity
F3X89_29235	COG3161	chorismate lyase activity
F3X89_29245	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F3X89_29320	COG0745	RESPONSE REGULATOR receiver
F3X89_29330	COG1192	Involved in chromosome partitioning
F3X89_29340	COG3843	relaxase mobilization nuclease domain protein
F3X89_29345	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
F3X89_29350	COG3505	Type IV secretory pathway VirD4
F3X89_29385	COG0747	negative chemotaxis
F3X89_29405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3X89_29410	COG0584	glycerophosphoryl diester phosphodiesterase