locus-tag	class	description
KHC17_00010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KHC17_00025	COG3257	ureidoglycine aminohydrolase activity
KHC17_00035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_00040	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHC17_00050	COG1129	ABC transporter
KHC17_00055	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_00060	COG1879	ABC-type sugar transport system periplasmic component
KHC17_00065	COG0583	DNA-binding transcription factor activity
KHC17_00120	COG2963	transposase activity
KHC17_00160	COG0456	acetyltransferase
KHC17_00200	COG1484	DNA-dependent DNA replication
KHC17_00255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_00260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KHC17_00270	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
KHC17_00345	COG3047	cAMP biosynthetic process
KHC17_00355	COG3842	ATPase activity
KHC17_00360	COG0395	ABC-type sugar transport system, permease component
KHC17_00365	COG1175	transmembrane transport
KHC17_00370	COG1653	transport
KHC17_00380	COG0523	cobalamin synthesis protein
KHC17_00395	COG0523	cobalamin synthesis protein
KHC17_00400	COG1121	(ABC) transporter
KHC17_00410	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHC17_00425	COG0626	cystathionine gamma-synthase activity
KHC17_00430	COG2182	Extracellular solute-binding protein
KHC17_00435	COG1175	transmembrane transport
KHC17_00440	COG0395	ABC-type sugar transport system, permease component
KHC17_00450	COG1609	Transcriptional regulator
KHC17_00455	COG2223	nitrite transmembrane transporter activity
KHC17_00505	COG2186	Transcriptional regulator
KHC17_00510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHC17_00515	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KHC17_00520	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_00525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_00530	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_00535	COG3618	amidohydrolase
KHC17_00540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_00560	COG1175	transmembrane transport
KHC17_00565	COG0395	ABC-type sugar transport system, permease component
KHC17_00570	COG3842	ATPase activity
KHC17_00585	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KHC17_00610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_00615	COG0577	efflux transmembrane transporter activity
KHC17_00615	COG1136	(ABC) transporter
KHC17_00620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHC17_00645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHC17_00655	COG1278	Cold shock
KHC17_00665	COG0673	inositol 2-dehydrogenase activity
KHC17_00680	COG0673	inositol 2-dehydrogenase activity
KHC17_00685	COG1309	transcriptional regulator
KHC17_00690	COG1653	transport
KHC17_00695	COG1175	transmembrane transport
KHC17_00700	COG0395	ABC-type sugar transport system, permease component
KHC17_00705	COG3842	ATPase activity
KHC17_00710	COG1082	Xylose isomerase domain protein TIM barrel
KHC17_00725	COG1609	Transcriptional regulator
KHC17_00755	COG1175	transmembrane transport
KHC17_00760	COG0395	ABC-type sugar transport system, permease component
KHC17_00765	COG3842	ATPase activity
KHC17_00770	COG0395	ABC-type sugar transport system, permease component
KHC17_00780	COG1653	transport
KHC17_00815	COG3842	ATPase activity
KHC17_00830	COG0395	ABC-type sugar transport system, permease component
KHC17_00880	COG2233	PERMEase
KHC17_00885	COG0702	epimerase
KHC17_00900	COG0372	Belongs to the citrate synthase family
KHC17_00905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHC17_00910	COG2140	Oxalate decarboxylase
KHC17_00920	COG4566	intracellular signal transduction
KHC17_00925	COG4566	intracellular signal transduction
KHC17_00935	COG0243	molybdopterin cofactor binding
KHC17_00940	COG0783	Belongs to the Dps family
KHC17_00960	COG0596	Alpha beta hydrolase
KHC17_00970	COG1764	response to oxidative stress
KHC17_00985	COG0596	Alpha beta hydrolase
KHC17_01015	COG2814	Major facilitator Superfamily
KHC17_01020	COG4178	(ABC) transporter
KHC17_01035	COG0697	spore germination
KHC17_01055	COG0640	Transcriptional regulator
KHC17_01075	COG1309	transcriptional regulator
KHC17_01090	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_01095	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_01140	COG0583	DNA-binding transcription factor activity
KHC17_01145	COG1024	Enoyl-CoA hydratase
KHC17_01160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_01185	COG4227	nucleotidyltransferase activity
KHC17_01190	COG3550	peptidyl-serine autophosphorylation
KHC17_01200	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHC17_01200	COG0475	glutathione-regulated potassium exporter activity
KHC17_01220	COG1349	DNA-binding transcription factor activity
KHC17_01225	COG1879	ABC-type sugar transport system periplasmic component
KHC17_01235	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_01240	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_01260	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_01270	COG0270	DNA (cytosine-5-)-methyltransferase activity
KHC17_01280	COG0326	Molecular chaperone. Has ATPase activity
KHC17_01305	COG4372	Transposase
KHC17_01315	COG2963	transposase activity
KHC17_01325	COG2963	transposase activity
KHC17_01350	COG2161	toxin-antitoxin pair type II binding
KHC17_01375	COG2161	toxin-antitoxin pair type II binding
KHC17_01415	COG2963	transposase activity
KHC17_01485	COG4529	Protein conserved in bacteria
KHC17_01510	COG1063	alcohol dehydrogenase
KHC17_01615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHC17_01655	COG3547	Transposase (IS116 IS110 IS902 family)
KHC17_01665	COG1484	DNA-dependent DNA replication
KHC17_01670	COG3547	Transposase (IS116 IS110 IS902 family)
KHC17_01700	COG1063	alcohol dehydrogenase
KHC17_01735	COG2963	transposase activity
KHC17_01765	COG1309	transcriptional regulator
KHC17_01770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KHC17_01775	COG2080	2 iron, 2 sulfur cluster binding
KHC17_01780	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
KHC17_01785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHC17_01790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHC17_01810	COG0438	transferase activity, transferring glycosyl groups
KHC17_01830	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHC17_01860	COG4566	intracellular signal transduction
KHC17_01865	COG2197	response regulator
KHC17_01870	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KHC17_01875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHC17_01880	COG4310	Domain of unknown function (DUF2172)
KHC17_01885	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KHC17_01895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHC17_01900	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KHC17_01905	COG2197	response regulator
KHC17_01920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHC17_01940	COG2358	TRAP transporter, solute receptor (TAXI family
KHC17_01965	COG1484	DNA-dependent DNA replication
KHC17_02010	COG2197	response regulator
KHC17_02015	COG3237	CsbD-like
KHC17_02040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KHC17_02050	COG2814	Major facilitator Superfamily
KHC17_02055	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KHC17_02060	COG1522	sequence-specific DNA binding
KHC17_02065	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_02070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHC17_02075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHC17_02080	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KHC17_02085	COG2423	ornithine cyclodeaminase activity
KHC17_02090	COG0006	proline dipeptidase activity
KHC17_02095	COG3608	succinylglutamate desuccinylase aspartoacylase
KHC17_02100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_02105	COG0765	amino acid transport
KHC17_02110	COG0765	amino acid transport
KHC17_02115	COG1126	abc transporter atp-binding protein
KHC17_02125	COG1082	Xylose isomerase domain protein TIM barrel
KHC17_02140	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_02145	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_02150	COG1129	ABC transporter
KHC17_02175	COG3284	Transcriptional regulator
KHC17_02180	COG1063	alcohol dehydrogenase
KHC17_02190	COG0110	maltose O-acetyltransferase activity
KHC17_02195	COG1049	propionate catabolic process, 2-methylcitrate cycle
KHC17_02220	COG0488	(ABC) transporter
KHC17_02225	COG5265	(ABC) transporter
KHC17_02260	COG0395	ABC-type sugar transport system, permease component
KHC17_02265	COG3842	ATPase activity
KHC17_02275	COG0483	inositol monophosphate 1-phosphatase activity
KHC17_02285	COG0405	Gamma-glutamyltransferase
KHC17_02290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_02295	COG0601	transmembrane transport
KHC17_02300	COG0747	negative chemotaxis
KHC17_02305	COG2186	Transcriptional regulator
KHC17_02315	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_02320	COG4172	Belongs to the ABC transporter superfamily
KHC17_02325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_02330	COG0601	transmembrane transport
KHC17_02335	COG0747	negative chemotaxis
KHC17_02340	COG2186	Transcriptional regulator
KHC17_02350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_02355	COG2223	nitrite transmembrane transporter activity
KHC17_02365	COG3383	formate dehydrogenase (NAD+) activity
KHC17_02390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHC17_02395	COG1802	Transcriptional regulator
KHC17_02400	COG4608	Belongs to the ABC transporter superfamily
KHC17_02405	COG0444	Belongs to the ABC transporter superfamily
KHC17_02410	COG0402	S-adenosylhomocysteine deaminase activity
KHC17_02420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_02425	COG0601	transmembrane transport
KHC17_02435	COG0402	S-adenosylhomocysteine deaminase activity
KHC17_02440	COG3300	MHYT domain
KHC17_02440	COG5001	Diguanylate cyclase
KHC17_02445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHC17_02455	COG0765	amino acid transport
KHC17_02460	COG0765	amino acid transport
KHC17_02465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_02480	COG3938	Belongs to the proline racemase family
KHC17_02490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_02500	COG0765	amino acid transport
KHC17_02515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KHC17_02520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_02530	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHC17_02550	COG0842	Transport permease protein
KHC17_02555	COG1129	ABC transporter
KHC17_02555	COG0842	Transport permease protein
KHC17_02560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_02565	COG1486	melibiose metabolic process
KHC17_02570	COG4172	Belongs to the ABC transporter superfamily
KHC17_02575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_02580	COG0601	transmembrane transport
KHC17_02585	COG0747	negative chemotaxis
KHC17_02590	COG1486	melibiose metabolic process
KHC17_02620	COG1940	carbohydrate kinase activity
KHC17_02625	COG2182	Extracellular solute-binding protein
KHC17_02630	COG1175	transmembrane transport
KHC17_02635	COG0395	ABC-type sugar transport system, permease component
KHC17_02640	COG0165	Argininosuccinate lyase
KHC17_02645	COG3842	ATPase activity
KHC17_02650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_02655	COG3119	arylsulfatase activity
KHC17_02670	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_02715	COG1120	ATPase activity
KHC17_02720	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_02725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_02735	COG4774	siderophore transport
KHC17_02750	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KHC17_02765	COG1392	Phosphate transport regulator
KHC17_02770	COG0306	phosphate transporter
KHC17_02775	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHC17_02785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KHC17_02795	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_02800	COG3300	MHYT domain
KHC17_02800	COG5001	Diguanylate cyclase
KHC17_02820	COG2186	Transcriptional regulator
KHC17_02830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_02835	COG0444	Belongs to the ABC transporter superfamily
KHC17_02845	COG3842	ATPase activity
KHC17_02850	COG0395	ABC-type sugar transport system, permease component
KHC17_02865	COG1233	COG1233 Phytoene dehydrogenase and related
KHC17_02875	COG0210	DNA helicase
KHC17_02880	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KHC17_02885	COG1088	dTDP-glucose 4,6-dehydratase activity
KHC17_02890	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHC17_02895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHC17_02905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHC17_02910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KHC17_02940	COG0277	FAD linked oxidase domain protein
KHC17_02945	COG0546	phosphoglycolate phosphatase activity
KHC17_02945	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KHC17_02960	COG3436	PFAM IS66 Orf2 family protein
KHC17_02965	COG4372	Transposase
KHC17_02980	COG1132	(ABC) transporter
KHC17_03000	COG0583	DNA-binding transcription factor activity
KHC17_03005	COG0667	Aldo Keto reductase
KHC17_03010	COG0385	Bile acid
KHC17_03040	COG1396	sequence-specific DNA binding
KHC17_03045	COG3550	peptidyl-serine autophosphorylation
KHC17_03105	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KHC17_03130	COG3706	GGDEF domain
KHC17_03145	COG3712	iron ion homeostasis
KHC17_03155	COG2814	Major facilitator Superfamily
KHC17_03175	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KHC17_03185	COG3842	ATPase activity
KHC17_03190	COG1175	transmembrane transport
KHC17_03195	COG0395	ABC-type sugar transport system, permease component
KHC17_03200	COG1609	Transcriptional regulator
KHC17_03210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KHC17_03215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_03235	COG1538	Outer membrane efflux protein
KHC17_03255	COG1116	anion transmembrane transporter activity
KHC17_03275	COG0402	S-adenosylhomocysteine deaminase activity
KHC17_03280	COG3443	Belongs to the bacterial solute-binding protein 9 family
KHC17_03285	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHC17_03290	COG1121	(ABC) transporter
KHC17_03305	COG0673	inositol 2-dehydrogenase activity
KHC17_03310	COG1082	Xylose isomerase domain protein TIM barrel
KHC17_03325	COG1609	Transcriptional regulator
KHC17_03330	COG0183	Belongs to the thiolase family
KHC17_03335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KHC17_03345	COG1414	Transcriptional regulator
KHC17_03360	COG0583	DNA-binding transcription factor activity
KHC17_03370	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHC17_03375	COG3485	protocatechuate 3,4-dioxygenase
KHC17_03380	COG3485	protocatechuate 3,4-dioxygenase
KHC17_03400	COG0747	negative chemotaxis
KHC17_03410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_03430	COG0683	leucine binding
KHC17_03445	COG0411	ABC transporter
KHC17_03460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_03465	COG3962	Belongs to the TPP enzyme family
KHC17_03475	COG3718	enzyme involved in inositol metabolism
KHC17_03485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHC17_03490	COG1609	Transcriptional regulator
KHC17_03495	COG1846	Transcriptional regulator
KHC17_03505	COG0523	cobalamin synthesis protein
KHC17_03535	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KHC17_03555	COG0800	Aldolase
KHC17_03560	COG2954	triphosphatase activity
KHC17_03570	COG1054	Belongs to the UPF0176 family
KHC17_03575	COG5001	Diguanylate cyclase
KHC17_03575	COG3300	MHYT domain
KHC17_03585	COG2011	ABC-type metal ion transport system permease component
KHC17_03590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHC17_03595	COG0778	Nitroreductase
KHC17_03605	COG4172	Belongs to the ABC transporter superfamily
KHC17_03610	COG1473	amidohydrolase
KHC17_03620	COG0601	transmembrane transport
KHC17_03625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_03635	COG0693	protein deglycase activity
KHC17_03640	COG0154	amidase activity
KHC17_03645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_03655	COG0747	negative chemotaxis
KHC17_03660	COG0583	DNA-binding transcription factor activity
KHC17_03670	COG0444	Belongs to the ABC transporter superfamily
KHC17_03675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_03680	COG0601	transmembrane transport
KHC17_03685	COG0747	negative chemotaxis
KHC17_03700	COG1473	amidohydrolase
KHC17_03710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHC17_03720	COG3842	ATPase activity
KHC17_03730	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHC17_03740	COG1609	Transcriptional regulator
KHC17_03745	COG0583	DNA-binding transcription factor activity
KHC17_03750	COG1960	acyl-CoA dehydrogenase activity
KHC17_03755	COG1629	transport
KHC17_03755	COG4774	siderophore transport
KHC17_03765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHC17_03770	COG1120	ATPase activity
KHC17_03775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_03780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_03790	COG2375	cellular response to nickel ion
KHC17_03800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHC17_03805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KHC17_03805	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KHC17_03815	COG1169	isochorismate synthase
KHC17_03820	COG1021	2,3-dihydroxybenzoate-AMP ligase
KHC17_03825	COG1535	isochorismatase
KHC17_03825	COG3433	isochorismatase activity
KHC17_03830	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_03845	COG3005	denitrification pathway
KHC17_03870	COG4459	periplasmic nitrate reductase
KHC17_03920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KHC17_03925	COG0163	prenyltransferase activity
KHC17_03940	COG1845	cytochrome c oxidase, subunit III
KHC17_03955	COG3256	nitric oxide reductase
KHC17_03960	COG0714	Associated with various cellular activities
KHC17_04010	COG1609	Transcriptional regulator
KHC17_04015	COG0673	inositol 2-dehydrogenase activity
KHC17_04030	COG1175	transmembrane transport
KHC17_04035	COG0395	ABC-type sugar transport system, permease component
KHC17_04040	COG3842	ATPase activity
KHC17_04060	COG0483	inositol monophosphate 1-phosphatase activity
KHC17_04065	COG5001	Diguanylate cyclase
KHC17_04065	COG3300	MHYT domain
KHC17_04195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHC17_04205	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_04215	COG1879	ABC-type sugar transport system periplasmic component
KHC17_04225	COG1063	alcohol dehydrogenase
KHC17_04230	COG1309	transcriptional regulator
KHC17_04245	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHC17_04255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHC17_04255	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHC17_04265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_04270	COG1917	Cupin 2, conserved barrel domain protein
KHC17_04270	COG4977	sequence-specific DNA binding
KHC17_04285	COG1845	cytochrome c oxidase, subunit III
KHC17_04290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHC17_04295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHC17_04310	COG1335	isochorismatase
KHC17_04330	COG1177	transmembrane transport
KHC17_04335	COG3842	ATPase activity
KHC17_04345	COG1846	Transcriptional regulator
KHC17_04345	COG1940	carbohydrate kinase activity
KHC17_04360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KHC17_04365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KHC17_04385	COG1522	sequence-specific DNA binding
KHC17_04390	COG2376	Dihydroxyacetone kinase
KHC17_04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHC17_04435	COG3842	ATPase activity
KHC17_04440	COG0395	ABC-type sugar transport system, permease component
KHC17_04445	COG1175	transmembrane transport
KHC17_04450	COG1653	transport
KHC17_04455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHC17_04480	COG2144	transferase activity, transferring acyl groups
KHC17_04490	COG2072	flavoprotein involved in K transport
KHC17_04510	COG0583	DNA-binding transcription factor activity
KHC17_04515	COG0183	Belongs to the thiolase family
KHC17_04525	COG1024	Enoyl-CoA hydratase
KHC17_04545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KHC17_04580	COG1024	Enoyl-CoA hydratase
KHC17_04580	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHC17_04590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KHC17_04635	COG3436	PFAM IS66 Orf2 family protein
KHC17_04645	COG0582	viral genome integration into host DNA
KHC17_04650	COG0582	viral genome integration into host DNA
KHC17_04655	COG3436	PFAM IS66 Orf2 family protein
KHC17_04660	COG4372	Transposase
KHC17_04665	COG3012	SEC-C Motif Domain Protein
KHC17_04700	COG0741	lytic transglycosylase activity
KHC17_04700	COG1196	nuclear chromosome segregation
KHC17_04700	COG0739	heme binding
KHC17_04705	COG0542	response to heat
KHC17_04715	COG2890	protein-(glutamine-N5) methyltransferase activity
KHC17_04720	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHC17_04745	COG0019	diaminopimelate decarboxylase activity
KHC17_04760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHC17_04770	COG3920	Histidine kinase
KHC17_04780	COG0784	Response regulator, receiver
KHC17_04795	COG1522	sequence-specific DNA binding
KHC17_04805	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_04810	COG0583	DNA-binding transcription factor activity
KHC17_04815	COG0435	Glutathione S-transferase
KHC17_04825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KHC17_04830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHC17_04835	COG0189	ligase activity
KHC17_04855	COG0693	protein deglycase activity
KHC17_04880	COG1285	pathogenesis
KHC17_04885	COG3685	Protein conserved in bacteria
KHC17_04890	COG4993	Dehydrogenase
KHC17_04900	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_04905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHC17_04935	COG0411	ABC transporter
KHC17_04950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHC17_04965	COG0246	Mannitol dehydrogenase
KHC17_04970	COG4608	Belongs to the ABC transporter superfamily
KHC17_04975	COG0444	Belongs to the ABC transporter superfamily
KHC17_04980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_04985	COG0601	transmembrane transport
KHC17_04990	COG0747	negative chemotaxis
KHC17_04995	COG0006	proline dipeptidase activity
KHC17_05000	COG4221	oxidoreductase activity
KHC17_05030	COG0539	negative regulation of cytoplasmic translation
KHC17_05035	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KHC17_05065	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHC17_05070	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KHC17_05100	COG1294	oxidase, subunit
KHC17_05110	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHC17_05115	COG4988	ABC transporter
KHC17_05125	COG1063	alcohol dehydrogenase
KHC17_05130	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_05135	COG2084	Dehydrogenase
KHC17_05145	COG1522	sequence-specific DNA binding
KHC17_05150	COG1794	racemase activity, acting on amino acids and derivatives
KHC17_05160	COG0058	SHG alpha-glucan phosphorylase activity
KHC17_05165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHC17_05170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHC17_05175	COG0297	glycogen (starch) synthase activity
KHC17_05180	COG0033	Phosphoglucomutase
KHC17_05205	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHC17_05205	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHC17_05220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_05225	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KHC17_05245	COG1215	transferase activity, transferring glycosyl groups
KHC17_05250	COG2327	Polysaccharide pyruvyl transferase
KHC17_05255	COG0463	Glycosyl transferase, family 2
KHC17_05260	COG2244	polysaccharide biosynthetic process
KHC17_05265	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHC17_05270	COG2273	Hydrolase Family 16
KHC17_05275	COG0438	transferase activity, transferring glycosyl groups
KHC17_05280	COG1215	transferase activity, transferring glycosyl groups
KHC17_05285	COG1215	transferase activity, transferring glycosyl groups
KHC17_05290	COG1215	transferase activity, transferring glycosyl groups
KHC17_05295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHC17_05300	COG0489	protein tyrosine kinase activity
KHC17_05300	COG3206	protein involved in exopolysaccharide biosynthesis
KHC17_05310	COG0784	Response regulator, receiver
KHC17_05310	COG4191	Histidine kinase
KHC17_05320	COG4176	ABC-type proline glycine betaine transport system permease component
KHC17_05325	COG3448	diguanylate cyclase activity
KHC17_05325	COG4175	Glycine betaine
KHC17_05340	COG0564	pseudouridine synthase activity
KHC17_05345	COG0500	methyltransferase
KHC17_05355	COG2133	pyrroloquinoline quinone binding
KHC17_05365	COG2197	response regulator
KHC17_05370	COG4585	Histidine kinase
KHC17_05375	COG1879	ABC-type sugar transport system periplasmic component
KHC17_05380	COG1129	ABC transporter
KHC17_05385	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_05395	COG3386	PFAM SMP-30 Gluconolaconase
KHC17_05400	COG2137	regulation of response to DNA damage stimulus
KHC17_05415	COG1120	ATPase activity
KHC17_05430	COG4774	siderophore transport
KHC17_05435	COG0583	DNA-binding transcription factor activity
KHC17_05445	COG2194	sulfuric ester hydrolase activity
KHC17_05460	COG0477	Major facilitator Superfamily
KHC17_05480	COG0673	inositol 2-dehydrogenase activity
KHC17_05485	COG0697	spore germination
KHC17_05495	COG0010	Belongs to the arginase family
KHC17_05565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_05575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_05580	COG0601	transmembrane transport
KHC17_05585	COG0747	negative chemotaxis
KHC17_05595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KHC17_05600	COG1454	alcohol dehydrogenase
KHC17_05605	COG2186	Transcriptional regulator
KHC17_05640	COG2308	Evidence 4 Homologs of previously reported genes of
KHC17_05640	COG2307	Protein conserved in bacteria
KHC17_05655	COG0488	(ABC) transporter
KHC17_05660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHC17_05665	COG2186	Transcriptional regulator
KHC17_05680	COG1175	transmembrane transport
KHC17_05685	COG0395	ABC-type sugar transport system, permease component
KHC17_05695	COG3842	ATPase activity
KHC17_05720	COG1304	FMN binding
KHC17_05730	COG0583	DNA-binding transcription factor activity
KHC17_05735	COG2828	Protein conserved in bacteria
KHC17_05750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_05770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_05785	COG0583	DNA-binding transcription factor activity
KHC17_05800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHC17_05820	COG0583	DNA-binding transcription factor activity
KHC17_05835	COG4221	oxidoreductase activity
KHC17_05840	COG0625	glutathione transferase activity
KHC17_05850	COG1566	PFAM secretion protein HlyD family protein
KHC17_05860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHC17_05865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHC17_05880	COG0534	Mate efflux family protein
KHC17_05885	COG0028	Belongs to the TPP enzyme family
KHC17_05890	COG0583	DNA-binding transcription factor activity
KHC17_05910	COG0765	amino acid transport
KHC17_05915	COG1126	abc transporter atp-binding protein
KHC17_05920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_05935	COG0673	inositol 2-dehydrogenase activity
KHC17_05960	COG1609	Transcriptional regulator
KHC17_06010	COG0402	S-adenosylhomocysteine deaminase activity
KHC17_06015	COG1228	amidohydrolase
KHC17_06020	COG2986	histidine ammonia-lyase
KHC17_06030	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KHC17_06065	COG1192	Involved in chromosome partitioning
KHC17_06070	COG1475	DNA binding
KHC17_06075	COG1414	Transcriptional regulator
KHC17_06085	COG4467	Involved in initiation control of chromosome replication
KHC17_06110	COG4771	TonB-dependent receptor
KHC17_06120	COG0366	Alpha amylase catalytic
KHC17_06125	COG4770	biotin carboxylase activity
KHC17_06130	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KHC17_06135	COG4336	lyase activity
KHC17_06140	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KHC17_06145	COG1914	H( )-stimulated, divalent metal cation uptake system
KHC17_06150	COG1802	Transcriptional regulator
KHC17_06155	COG3707	response regulator
KHC17_06165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHC17_06170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_06175	COG1116	anion transmembrane transporter activity
KHC17_06180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KHC17_06190	COG0243	molybdopterin cofactor binding
KHC17_06195	COG1648	precorrin-2 dehydrogenase activity
KHC17_06195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHC17_06210	COG3842	ATPase activity
KHC17_06225	COG0395	ABC-type sugar transport system, permease component
KHC17_06240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHC17_06255	COG0071	Belongs to the small heat shock protein (HSP20) family
KHC17_06290	COG1609	Transcriptional regulator
KHC17_06295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_06300	COG1914	H( )-stimulated, divalent metal cation uptake system
KHC17_06340	COG1595	DNA-templated transcription, initiation
KHC17_06355	COG0395	ABC-type sugar transport system, permease component
KHC17_06380	COG3220	belongs to the UPF0276 family
KHC17_06415	COG0840	transmembrane signaling receptor activity
KHC17_06420	COG0583	DNA-binding transcription factor activity
KHC17_06425	COG0346	lactoylglutathione lyase activity
KHC17_06440	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KHC17_06460	COG0583	DNA-binding transcription factor activity
KHC17_06465	COG0477	Major facilitator Superfamily
KHC17_06500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KHC17_06510	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KHC17_06515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHC17_06520	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHC17_06530	COG0492	ferredoxin-NADP+ reductase activity
KHC17_06550	COG2358	TRAP transporter, solute receptor (TAXI family
KHC17_06570	COG2204	response regulator
KHC17_06580	COG3734	2-keto-3-deoxy-galactonokinase
KHC17_06585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_06590	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_06595	COG1653	transport
KHC17_06600	COG1175	transmembrane transport
KHC17_06605	COG0395	ABC-type sugar transport system, permease component
KHC17_06610	COG3842	ATPase activity
KHC17_06615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KHC17_06620	COG1414	Transcriptional regulator
KHC17_06625	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_06660	COG1082	Xylose isomerase domain protein TIM barrel
KHC17_06665	COG0673	inositol 2-dehydrogenase activity
KHC17_06670	COG1082	Xylose isomerase domain protein TIM barrel
KHC17_06680	COG1609	Transcriptional regulator
KHC17_06690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHC17_06690	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHC17_06695	COG4311	Sarcosine oxidase, delta subunit
KHC17_06735	COG2186	Transcriptional regulator
KHC17_06740	COG1027	Aspartate ammonia-lyase
KHC17_06750	COG0252	asparaginase activity
KHC17_06760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KHC17_06770	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KHC17_06775	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KHC17_06780	COG2205	protein histidine kinase activity
KHC17_06795	COG0067	glutamate synthase
KHC17_06795	COG0070	glutamate synthase
KHC17_06795	COG0069	glutamate synthase activity
KHC17_06805	COG2205	protein histidine kinase activity
KHC17_06820	COG2951	lytic endotransglycosylase activity
KHC17_06825	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KHC17_06850	COG0330	HflC and HflK could
KHC17_06855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KHC17_06860	COG0737	Belongs to the 5'-nucleotidase family
KHC17_06870	COG5310	Homospermidine synthase
KHC17_06880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHC17_06885	COG1164	Oligoendopeptidase f
KHC17_06890	COG2204	response regulator
KHC17_06895	COG3108	Peptidase M15
KHC17_06905	COG0469	pyruvate kinase activity
KHC17_06925	COG3750	Belongs to the UPF0335 family
KHC17_06935	COG0457	Tetratricopeptide repeat
KHC17_06940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KHC17_06945	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHC17_06950	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHC17_06980	COG0483	inositol monophosphate 1-phosphatase activity
KHC17_07000	COG1132	(ABC) transporter
KHC17_07005	COG0254	rRNA binding
KHC17_07050	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_07065	COG1414	Transcriptional regulator
KHC17_07075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_07080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KHC17_07080	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KHC17_07090	COG3588	fructose-bisphosphate aldolase
KHC17_07095	COG0126	phosphoglycerate kinase activity
KHC17_07135	COG1253	flavin adenine dinucleotide binding
KHC17_07145	COG1692	metallophosphoesterase
KHC17_07160	COG0217	transcriptional regulatory protein
KHC17_07165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHC17_07170	COG0840	transmembrane signaling receptor activity
KHC17_07175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KHC17_07180	COG0632	four-way junction helicase activity
KHC17_07185	COG2255	four-way junction helicase activity
KHC17_07200	COG0494	nUDIX hydrolase
KHC17_07210	COG0824	Thioesterase
KHC17_07230	COG0823	Involved in the tonB-independent uptake of proteins
KHC17_07235	COG2885	chlorophyll binding
KHC17_07245	COG0037	tRNA processing
KHC17_07250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHC17_07255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHC17_07285	COG1735	metal-dependent hydrolase with the TIM-barrel fold
KHC17_07290	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_07305	COG1609	Transcriptional regulator
KHC17_07315	COG1454	alcohol dehydrogenase
KHC17_07345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KHC17_07365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KHC17_07370	COG4251	negative regulation of phosphorylation
KHC17_07375	COG0784	Response regulator, receiver
KHC17_07380	COG3920	Histidine kinase
KHC17_07380	COG2202	Pas domain
KHC17_07385	COG0784	Response regulator, receiver
KHC17_07390	COG2198	Histidine kinase
KHC17_07390	COG2205	protein histidine kinase activity
KHC17_07390	COG0784	Response regulator, receiver
KHC17_07390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_07400	COG3920	Histidine kinase
KHC17_07415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHC17_07430	COG0482	sulfurtransferase activity
KHC17_07465	COG2835	tetraacyldisaccharide 4'-kinase activity
KHC17_07470	COG2373	Large extracellular alpha-helical protein
KHC17_07475	COG4953	penicillin-binding protein 1C
KHC17_07485	COG1473	amidohydrolase
KHC17_07490	COG1686	Belongs to the peptidase S11 family
KHC17_07495	COG0523	cobalamin synthesis protein
KHC17_07500	COG0425	Belongs to the sulfur carrier protein TusA family
KHC17_07500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHC17_07505	COG3034	peptidoglycan biosynthetic process
KHC17_07510	COG0825	malonyl-CoA metabolic process
KHC17_07515	COG4974	Belongs to the 'phage' integrase family
KHC17_07525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KHC17_07530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHC17_07565	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KHC17_07570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KHC17_07585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHC17_07590	COG2226	methyltransferase
KHC17_07595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHC17_07600	COG0287	Prephenate dehydrogenase
KHC17_07610	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
KHC17_07630	COG2884	Cell division ATP-binding protein ftsE
KHC17_07665	COG0165	Argininosuccinate lyase
KHC17_07670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KHC17_07680	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHC17_07690	COG2086	electron transfer activity
KHC17_07700	COG2096	Adenosyltransferase
KHC17_07710	COG0300	oxidoreductase activity
KHC17_07720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHC17_07730	COG1396	sequence-specific DNA binding
KHC17_07730	COG3800	Transcriptional regulator
KHC17_07735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHC17_07740	COG0625	glutathione transferase activity
KHC17_07750	COG4770	biotin carboxylase activity
KHC17_07755	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHC17_07755	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KHC17_07760	COG0346	lactoylglutathione lyase activity
KHC17_07775	COG4213	ABC transporter substrate-binding protein
KHC17_07780	COG4214	carbohydrate transport
KHC17_07785	COG1129	ABC transporter
KHC17_07795	COG1396	sequence-specific DNA binding
KHC17_07840	COG2273	Hydrolase Family 16
KHC17_07840	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
KHC17_07845	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHC17_07860	COG0438	transferase activity, transferring glycosyl groups
KHC17_07885	COG3206	protein involved in exopolysaccharide biosynthesis
KHC17_07885	COG0489	protein tyrosine kinase activity
KHC17_07895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KHC17_07910	COG2244	polysaccharide biosynthetic process
KHC17_07920	COG0438	transferase activity, transferring glycosyl groups
KHC17_07935	COG3273	potassium ion transport
KHC17_07935	COG0471	metal ion transport
KHC17_07945	COG1461	Dihydroxyacetone kinase
KHC17_07950	COG0789	Transcriptional regulator
KHC17_08045	COG0697	spore germination
KHC17_08050	COG0653	protein targeting
KHC17_08055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KHC17_08060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHC17_08070	COG0494	nUDIX hydrolase
KHC17_08085	COG2226	methyltransferase
KHC17_08090	COG1040	competence protein
KHC17_08100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHC17_08115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KHC17_08130	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KHC17_08145	COG4208	sulfate ABC transporter
KHC17_08150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KHC17_08155	COG4335	DNA alkylation repair
KHC17_08170	COG5001	Diguanylate cyclase
KHC17_08175	COG2264	protein methyltransferase activity
KHC17_08190	COG3254	rhamnose metabolic process
KHC17_08200	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_08205	COG1129	ABC transporter
KHC17_08215	COG1349	DNA-binding transcription factor activity
KHC17_08220	COG3347	Dehydrogenase
KHC17_08220	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_08225	COG4952	isomerase
KHC17_08230	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KHC17_08235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KHC17_08255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KHC17_08260	COG1960	acyl-CoA dehydrogenase activity
KHC17_08270	COG1960	acyl-CoA dehydrogenase activity
KHC17_08280	COG0022	dehydrogenase e1 component
KHC17_08290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHC17_08295	COG2391	methyltransferase activity
KHC17_08305	COG0640	Transcriptional regulator
KHC17_08310	COG3453	Protein conserved in bacteria
KHC17_08310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHC17_08320	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_08335	COG2186	Transcriptional regulator
KHC17_08345	COG0601	transmembrane transport
KHC17_08355	COG0444	Belongs to the ABC transporter superfamily
KHC17_08360	COG4608	Belongs to the ABC transporter superfamily
KHC17_08385	COG1522	sequence-specific DNA binding
KHC17_08395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_08430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_08435	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_08440	COG0473	3-isopropylmalate dehydrogenase activity
KHC17_08445	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_08455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHC17_08475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_08480	COG1120	ATPase activity
KHC17_08490	COG2226	methyltransferase
KHC17_08505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_08510	COG1120	ATPase activity
KHC17_08515	COG1595	DNA-templated transcription, initiation
KHC17_08535	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KHC17_08540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_08560	COG0673	inositol 2-dehydrogenase activity
KHC17_08565	COG0673	inositol 2-dehydrogenase activity
KHC17_08575	COG1175	transmembrane transport
KHC17_08580	COG0395	ABC-type sugar transport system, permease component
KHC17_08585	COG3842	ATPase activity
KHC17_08595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHC17_08600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KHC17_08605	COG2197	response regulator
KHC17_08610	COG0601	transmembrane transport
KHC17_08615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_08635	COG0747	negative chemotaxis
KHC17_08650	COG1446	asparaginase
KHC17_08670	COG1129	ABC transporter
KHC17_08675	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_08680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KHC17_08685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KHC17_08710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_08720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHC17_08725	COG2079	MmgE PrpD family protein
KHC17_08730	COG1126	abc transporter atp-binding protein
KHC17_08735	COG0765	amino acid transport
KHC17_08755	COG2390	Transcriptional regulator
KHC17_08765	COG1175	transmembrane transport
KHC17_08770	COG0395	ABC-type sugar transport system, permease component
KHC17_08785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHC17_08790	COG1069	ribulokinase activity
KHC17_08815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHC17_08825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHC17_08830	COG1414	Transcriptional regulator
KHC17_08835	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_08845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHC17_08850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHC17_08855	COG1121	(ABC) transporter
KHC17_08860	COG0803	Belongs to the bacterial solute-binding protein 9 family
KHC17_08870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KHC17_08875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHC17_08880	COG3273	potassium ion transport
KHC17_08880	COG0471	metal ion transport
KHC17_08885	COG1253	flavin adenine dinucleotide binding
KHC17_08890	COG1309	transcriptional regulator
KHC17_08910	COG1609	Transcriptional regulator
KHC17_08915	COG1070	Carbohydrate kinase
KHC17_08920	COG2115	Belongs to the xylose isomerase family
KHC17_08925	COG0280	phosphate acetyltransferase
KHC17_08925	COG0281	malic enzyme
KHC17_08940	COG1175	transmembrane transport
KHC17_08945	COG0395	ABC-type sugar transport system, permease component
KHC17_08950	COG3842	ATPase activity
KHC17_08960	COG0673	inositol 2-dehydrogenase activity
KHC17_08965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KHC17_08970	COG0720	synthase
KHC17_08975	COG0602	queuosine metabolic process
KHC17_08980	COG0673	inositol 2-dehydrogenase activity
KHC17_08990	COG3842	ATPase activity
KHC17_09005	COG1653	transport
KHC17_09010	COG1609	Transcriptional regulator
KHC17_09020	COG2094	Belongs to the DNA glycosylase MPG family
KHC17_09030	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_09040	COG1376	ErfK ybiS ycfS ynhG family protein
KHC17_09045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHC17_09055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KHC17_09060	COG1596	polysaccharide export
KHC17_09065	COG3307	-O-antigen
KHC17_09095	COG2197	response regulator
KHC17_09130	COG2942	2-epimerase
KHC17_09140	COG1215	transferase activity, transferring glycosyl groups
KHC17_09160	COG1473	amidohydrolase
KHC17_09170	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_09175	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KHC17_09180	COG1301	dicarboxylic acid transport
KHC17_09185	COG4191	Histidine kinase
KHC17_09190	COG2204	response regulator
KHC17_09205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_09210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHC17_09215	COG1522	sequence-specific DNA binding
KHC17_09220	COG0351	phosphomethylpyrimidine kinase
KHC17_09225	COG0352	thiamine-phosphate diphosphorylase activity
KHC17_09230	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHC17_09235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KHC17_09240	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_09250	COG1501	Belongs to the glycosyl hydrolase 31 family
KHC17_09255	COG0395	ABC-type sugar transport system, permease component
KHC17_09260	COG1175	transmembrane transport
KHC17_09265	COG1653	transport
KHC17_09270	COG3842	ATPase activity
KHC17_09275	COG2188	Transcriptional regulator
KHC17_09285	COG4989	oxidoreductase activity
KHC17_09310	COG0438	transferase activity, transferring glycosyl groups
KHC17_09315	COG0747	negative chemotaxis
KHC17_09320	COG0601	transmembrane transport
KHC17_09330	COG3964	amidohydrolase
KHC17_09345	COG1921	L-seryl-tRNASec selenium transferase activity
KHC17_09350	COG4172	Belongs to the ABC transporter superfamily
KHC17_09355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KHC17_09360	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_09375	COG1312	Catalyzes the dehydration of D-mannonate
KHC17_09380	COG1063	alcohol dehydrogenase
KHC17_09385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KHC17_09395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_09400	COG2186	Transcriptional regulator
KHC17_09405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHC17_09410	COG0850	regulation of cytokinetic process
KHC17_09415	COG2894	cell division
KHC17_09420	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KHC17_09430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_09435	COG5001	Diguanylate cyclase
KHC17_09450	COG0673	inositol 2-dehydrogenase activity
KHC17_09460	COG1653	transport
KHC17_09470	COG0395	ABC-type sugar transport system, permease component
KHC17_09475	COG3842	ATPase activity
KHC17_09485	COG0673	inositol 2-dehydrogenase activity
KHC17_09515	COG0587	DNA-directed DNA polymerase activity
KHC17_09525	COG2186	Transcriptional regulator
KHC17_09530	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_09535	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_09540	COG1129	ABC transporter
KHC17_09545	COG1879	ABC-type sugar transport system periplasmic component
KHC17_09550	COG0129	dihydroxy-acid dehydratase activity
KHC17_09560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KHC17_09565	COG4608	Belongs to the ABC transporter superfamily
KHC17_09570	COG0444	Belongs to the ABC transporter superfamily
KHC17_09575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_09580	COG0601	transmembrane transport
KHC17_09585	COG0747	negative chemotaxis
KHC17_09600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHC17_09605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHC17_09610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHC17_09615	COG1420	regulation of RNA biosynthetic process
KHC17_09620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHC17_09625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHC17_09630	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHC17_09640	COG1137	ATPase activity
KHC17_09645	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KHC17_09655	COG0616	signal peptide processing
KHC17_09660	COG0776	regulation of translation
KHC17_09670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KHC17_09675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHC17_09680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHC17_09695	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHC17_09700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KHC17_09705	COG0728	peptidoglycan biosynthetic process
KHC17_09715	COG0180	Tryptophanyl-tRNA synthetase
KHC17_09725	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KHC17_09730	COG1214	PFAM Peptidase M22, glycoprotease
KHC17_09735	COG0456	acetyltransferase
KHC17_09750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHC17_09755	COG1702	phosphate starvation-inducible protein PhoH
KHC17_09760	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHC17_09770	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KHC17_09775	COG1396	sequence-specific DNA binding
KHC17_09780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHC17_09785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KHC17_09790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_09800	COG0242	peptide deformylase activity
KHC17_09805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHC17_09810	COG0101	tRNA pseudouridine synthase activity
KHC17_09820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHC17_09825	COG2171	N-acyltransferase activity
KHC17_09835	COG0840	transmembrane signaling receptor activity
KHC17_09840	COG1957	nucleoside hydrolase
KHC17_09845	COG0071	Belongs to the small heat shock protein (HSP20) family
KHC17_09870	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KHC17_09880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KHC17_09885	COG0706	membrane insertase activity
KHC17_09890	COG0594	ribonuclease P activity
KHC17_09895	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KHC17_09900	COG0840	transmembrane signaling receptor activity
KHC17_09915	COG3842	ATPase activity
KHC17_09920	COG1175	transmembrane transport
KHC17_09925	COG0395	ABC-type sugar transport system, permease component
KHC17_09940	COG0427	acetyl-CoA hydrolase
KHC17_09950	COG3938	Belongs to the proline racemase family
KHC17_09955	COG0418	dihydroorotase activity
KHC17_09960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHC17_09980	COG0166	Belongs to the GPI family
KHC17_09985	COG0318	PFAM AMP-dependent synthetase and ligase
KHC17_09990	COG3842	ATPase activity
KHC17_09995	COG1840	ABC-type Fe3 transport system, periplasmic component
KHC17_10000	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KHC17_10005	COG4774	siderophore transport
KHC17_10055	COG2963	transposase activity
KHC17_10150	COG2326	polyphosphate kinase activity
KHC17_10155	COG5002	protein histidine kinase activity
KHC17_10160	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KHC17_10165	COG0573	inorganic phosphate transmembrane transporter activity
KHC17_10175	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KHC17_10180	COG0704	Plays a role in the regulation of phosphate uptake
KHC17_10185	COG0745	RESPONSE REGULATOR receiver
KHC17_10195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KHC17_10200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHC17_10210	COG2967	ApaG domain
KHC17_10220	COG0717	Belongs to the dCTP deaminase family
KHC17_10230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KHC17_10280	COG0167	dihydroorotate dehydrogenase activity
KHC17_10295	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KHC17_10315	COG1959	2 iron, 2 sulfur cluster binding
KHC17_10320	COG1201	RNA secondary structure unwinding
KHC17_10355	COG1960	acyl-CoA dehydrogenase activity
KHC17_10360	COG0183	Belongs to the thiolase family
KHC17_10365	COG1024	Enoyl-CoA hydratase
KHC17_10365	COG1250	3-hydroxyacyl-CoA dehydrogenase
KHC17_10435	COG0740	serine-type endopeptidase activity
KHC17_10485	COG1320	monovalent cation:proton antiporter activity
KHC17_10490	COG2212	antiporter activity
KHC17_10495	COG1863	multisubunit Na H antiporter MnhE subunit
KHC17_10500	COG0651	ATP synthesis coupled electron transport
KHC17_10505	COG1006	Multisubunit Na H antiporter MnhC subunit
KHC17_10510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KHC17_10510	COG2111	Na H antiporter
KHC17_10520	COG0840	transmembrane signaling receptor activity
KHC17_10530	COG0745	RESPONSE REGULATOR receiver
KHC17_10535	COG2198	Histidine kinase
KHC17_10535	COG0643	Histidine kinase
KHC17_10540	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KHC17_10545	COG2201	protein-glutamate methylesterase activity
KHC17_10550	COG0745	RESPONSE REGULATOR receiver
KHC17_10555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
KHC17_10565	COG1766	The M ring may be actively involved in energy transduction
KHC17_10570	COG2771	luxR family
KHC17_10580	COG0840	transmembrane signaling receptor activity
KHC17_10580	COG2972	Histidine kinase
KHC17_10585	COG2205	protein histidine kinase activity
KHC17_10585	COG2198	Histidine kinase
KHC17_10585	COG0784	Response regulator, receiver
KHC17_10590	COG1970	mechanosensitive ion channel activity
KHC17_10595	COG0436	Aminotransferase
KHC17_10610	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KHC17_10615	COG0424	maF-like protein
KHC17_10620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHC17_10630	COG5328	Belongs to the UPF0262 family
KHC17_10635	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHC17_10645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHC17_10675	COG1338	Plays a role in the flagellum-specific transport system
KHC17_10685	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KHC17_10695	COG1706	bacterial-type flagellum-dependent cell motility
KHC17_10700	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
KHC17_10705	COG4786	Flagellar basal body rod
KHC17_10710	COG1677	Flagellar hook-basal body complex protein FliE
KHC17_10715	COG1558	bacterial-type flagellum-dependent cell motility
KHC17_10720	COG1815	bacterial-type flagellum-dependent cell motility
KHC17_10725	COG1280	lysine exporter protein (LysE YggA)
KHC17_10735	COG1157	protein secretion by the type III secretion system
KHC17_10740	COG4786	Flagellar basal body rod
KHC17_10750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KHC17_10755	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHC17_10760	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHC17_10765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KHC17_10770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHC17_10790	COG1360	Flagellar Motor Protein
KHC17_10820	COG4786	Flagellar basal body rod
KHC17_10820	COG1256	bacterial-type flagellum assembly
KHC17_10835	COG5443	negative regulation of bacterial-type flagellum assembly
KHC17_10840	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KHC17_10850	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KHC17_10890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHC17_10895	COG1609	Transcriptional regulator
KHC17_10900	COG1653	transport
KHC17_10905	COG1175	transmembrane transport
KHC17_10910	COG0395	ABC-type sugar transport system, permease component
KHC17_10915	COG0366	Alpha amylase catalytic
KHC17_10920	COG3842	ATPase activity
KHC17_10930	COG3609	addiction module antidote protein, CC2985 family
KHC17_10945	COG0129	dihydroxy-acid dehydratase activity
KHC17_10950	COG0363	glucosamine-6-phosphate deaminase activity
KHC17_10955	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHC17_10965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_10975	COG2081	HI0933 family
KHC17_10995	COG2224	Isocitrate lyase
KHC17_11010	COG3842	ATPase activity
KHC17_11015	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHC17_11020	COG1177	transmembrane transport
KHC17_11030	COG2205	protein histidine kinase activity
KHC17_11040	COG0248	Ppx GppA phosphatase
KHC17_11045	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KHC17_11050	COG0477	Major facilitator Superfamily
KHC17_11080	COG0521	Mo-molybdopterin cofactor biosynthetic process
KHC17_11085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHC17_11095	COG0142	geranyltranstransferase activity
KHC17_11120	COG0752	glycyl-tRNA synthetase alpha subunit
KHC17_11125	COG1704	LemA family
KHC17_11130	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KHC17_11140	COG0751	glycine-tRNA ligase activity
KHC17_11145	COG1683	Conserved Protein
KHC17_11150	COG0840	transmembrane signaling receptor activity
KHC17_11160	COG0151	Belongs to the GarS family
KHC17_11165	COG2183	response to ionizing radiation
KHC17_11170	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KHC17_11180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KHC17_11195	COG0583	DNA-binding transcription factor activity
KHC17_11215	COG0306	phosphate transporter
KHC17_11225	COG0561	phosphatase activity
KHC17_11230	COG0438	transferase activity, transferring glycosyl groups
KHC17_11235	COG2186	Transcriptional regulator
KHC17_11245	COG0583	DNA-binding transcription factor activity
KHC17_11250	COG0277	FAD linked oxidase domain protein
KHC17_11255	COG0277	FAD linked oxidase domain protein
KHC17_11260	COG0247	lactate metabolic process
KHC17_11270	COG1376	ErfK ybiS ycfS ynhG family protein
KHC17_11275	COG2818	Glycosylase
KHC17_11285	COG2855	membrane
KHC17_11290	COG0583	DNA-binding transcription factor activity
KHC17_11310	COG0124	histidyl-tRNA synthetase
KHC17_11320	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KHC17_11325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KHC17_11330	COG2259	Doxx family
KHC17_11340	COG0459	protein refolding
KHC17_11345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHC17_11355	COG0196	riboflavin kinase activity
KHC17_11360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHC17_11370	COG0590	tRNA wobble adenosine to inosine editing
KHC17_11375	COG1187	pseudouridine synthase activity
KHC17_11380	COG0742	ribosomal rna small subunit methyltransferase
KHC17_11385	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHC17_11390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHC17_11390	COG0475	glutathione-regulated potassium exporter activity
KHC17_11395	COG0312	modulator of DNA gyrase
KHC17_11400	COG0483	inositol monophosphate 1-phosphatase activity
KHC17_11410	COG1519	Transferase
KHC17_11420	COG1663	tetraacyldisaccharide 4'-kinase activity
KHC17_11430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHC17_11435	COG0745	RESPONSE REGULATOR receiver
KHC17_11440	COG5001	Diguanylate cyclase
KHC17_11440	COG3300	MHYT domain
KHC17_11445	COG3386	PFAM SMP-30 Gluconolaconase
KHC17_11450	COG0800	Aldolase
KHC17_11455	COG3734	2-keto-3-deoxy-galactonokinase
KHC17_11460	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_11465	COG1414	Transcriptional regulator
KHC17_11470	COG2197	response regulator
KHC17_11480	COG0489	protein tyrosine kinase activity
KHC17_11485	COG0598	Magnesium transport protein CorA
KHC17_11490	COG3158	transport of potassium into the cell
KHC17_11505	COG0356	it plays a direct role in the translocation of protons across the membrane
KHC17_11515	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHC17_11520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHC17_11530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHC17_11550	COG0009	L-threonylcarbamoyladenylate synthase
KHC17_11560	COG4638	Rieske (2fe-2S)
KHC17_11585	COG1960	acyl-CoA dehydrogenase activity
KHC17_11595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHC17_11605	COG0840	transmembrane signaling receptor activity
KHC17_11615	COG1522	sequence-specific DNA binding
KHC17_11635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHC17_11640	COG1741	Belongs to the pirin family
KHC17_11645	COG1722	exodeoxyribonuclease VII activity
KHC17_11650	COG0123	including yeast histone deacetylase and acetoin utilization protein
KHC17_11655	COG1268	BioY protein
KHC17_11660	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHC17_11665	COG1122	ATPase activity
KHC17_11670	COG3214	Protein conserved in bacteria
KHC17_11675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KHC17_11675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KHC17_11680	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHC17_11695	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KHC17_11710	COG0259	pyridoxamine-phosphate oxidase activity
KHC17_11725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHC17_11735	COG0312	modulator of DNA gyrase
KHC17_11750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHC17_11755	COG0109	protoheme IX farnesyltransferase activity
KHC17_11760	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KHC17_11775	COG3346	SURF1 family
KHC17_11780	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHC17_11785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KHC17_11790	COG0328	RNA-DNA hybrid ribonuclease activity
KHC17_11805	COG0678	peroxiredoxin activity
KHC17_11805	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KHC17_11815	COG1678	Uncharacterized ACR, COG1678
KHC17_11830	COG5001	Diguanylate cyclase
KHC17_11830	COG3300	MHYT domain
KHC17_11835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHC17_11840	COG0612	Peptidase, M16
KHC17_11855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KHC17_11860	COG1802	Transcriptional regulator
KHC17_11875	COG2189	Belongs to the N(4) N(6)-methyltransferase family
KHC17_11885	COG1194	a g-specific adenine glycosylase
KHC17_11895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KHC17_11900	COG1196	nuclear chromosome segregation
KHC17_11905	COG2514	catechol 2,3-dioxygenase activity
KHC17_11910	COG0574	Belongs to the PEP-utilizing enzyme family
KHC17_11910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHC17_11925	COG1823	symporter activity
KHC17_11950	COG0579	oxidoreductase
KHC17_11965	COG2895	sulfate adenylyltransferase (ATP) activity
KHC17_11970	COG0175	sulfate reduction
KHC17_11975	COG0175	sulfate reduction
KHC17_11980	COG1959	2 iron, 2 sulfur cluster binding
KHC17_11985	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KHC17_11990	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KHC17_11995	COG4208	sulfate ABC transporter
KHC17_12000	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KHC17_12010	COG2203	Gaf domain
KHC17_12010	COG2200	EAL domain
KHC17_12010	COG2199	diguanylate cyclase activity
KHC17_12020	COG1309	transcriptional regulator
KHC17_12025	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_12030	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
KHC17_12075	COG0477	Major facilitator Superfamily
KHC17_12085	COG1793	dna ligase
KHC17_12105	COG1376	ErfK ybiS ycfS ynhG family protein
KHC17_12110	COG1376	ErfK ybiS ycfS ynhG family protein
KHC17_12115	COG1846	Transcriptional regulator
KHC17_12120	COG1764	response to oxidative stress
KHC17_12135	COG0488	(ABC) transporter
KHC17_12165	COG0583	DNA-binding transcription factor activity
KHC17_12170	COG4221	oxidoreductase activity
KHC17_12180	COG0433	COG0433 Predicted ATPase
KHC17_12190	COG1733	regulation of RNA biosynthetic process
KHC17_12195	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_12210	COG0656	L-ascorbic acid biosynthetic process
KHC17_12215	COG2378	regulation of single-species biofilm formation
KHC17_12225	COG4106	trans-aconitate 2-methyltransferase activity
KHC17_12230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHC17_12235	COG0840	transmembrane signaling receptor activity
KHC17_12240	COG0583	DNA-binding transcription factor activity
KHC17_12255	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KHC17_12265	COG3909	cytochrome
KHC17_12270	COG2010	Cytochrome c
KHC17_12300	COG0789	Transcriptional regulator
KHC17_12325	COG4175	Glycine betaine
KHC17_12325	COG0517	IMP dehydrogenase activity
KHC17_12330	COG4176	ABC-type proline glycine betaine transport system permease component
KHC17_12350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_12360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHC17_12360	COG2169	Transcriptional regulator
KHC17_12370	COG2514	catechol 2,3-dioxygenase activity
KHC17_12385	COG1272	protein, Hemolysin III
KHC17_12395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHC17_12400	COG2111	Na H antiporter
KHC17_12400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KHC17_12405	COG2111	Na H antiporter
KHC17_12410	COG1006	Multisubunit Na H antiporter MnhC subunit
KHC17_12415	COG0651	ATP synthesis coupled electron transport
KHC17_12420	COG1863	multisubunit Na H antiporter MnhE subunit
KHC17_12425	COG2212	antiporter activity
KHC17_12430	COG1320	monovalent cation:proton antiporter activity
KHC17_12435	COG4957	zinc ion binding
KHC17_12450	COG2166	iron-sulfur cluster assembly
KHC17_12460	COG2205	protein histidine kinase activity
KHC17_12510	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KHC17_12515	COG2983	Belongs to the UPF0260 family
KHC17_12525	COG3041	Addiction module toxin RelE StbE family
KHC17_12530	COG3077	Addiction module antitoxin, RelB DinJ family
KHC17_12535	COG2226	methyltransferase
KHC17_12590	COG1621	beta-fructofuranosidase activity
KHC17_12595	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KHC17_12645	COG4695	Portal protein
KHC17_12750	COG4235	cytochrome complex assembly
KHC17_12755	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KHC17_12760	COG1138	Cytochrome C-type biogenesis protein
KHC17_12765	COG3088	subunit of a heme lyase
KHC17_12770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHC17_12780	COG2205	protein histidine kinase activity
KHC17_12785	COG3011	Protein conserved in bacteria
KHC17_12795	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KHC17_12800	COG2202	Pas domain
KHC17_12800	COG2205	protein histidine kinase activity
KHC17_12810	COG0308	aminopeptidase N
KHC17_12815	COG0697	spore germination
KHC17_12830	COG0443	Heat shock 70 kDa protein
KHC17_12890	COG0604	alcohol dehydrogenase
KHC17_12895	COG1733	regulation of RNA biosynthetic process
KHC17_12900	COG1968	undecaprenyl-diphosphatase activity
KHC17_12905	COG2239	Acts as a magnesium transporter
KHC17_12910	COG2814	Major facilitator Superfamily
KHC17_12940	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHC17_12970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHC17_13015	COG0741	lytic transglycosylase activity
KHC17_13020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_13025	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KHC17_13030	COG0840	transmembrane signaling receptor activity
KHC17_13040	COG1758	RNA polymerase activity
KHC17_13060	COG0736	holo-[acyl-carrier-protein] synthase activity
KHC17_13065	COG0681	Belongs to the peptidase S26 family
KHC17_13070	COG0571	ribonuclease III activity
KHC17_13075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHC17_13080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHC17_13085	COG0784	Response regulator, receiver
KHC17_13090	COG1381	Involved in DNA repair and RecF pathway recombination
KHC17_13100	COG2226	methyltransferase
KHC17_13110	COG1418	mRNA catabolic process
KHC17_13120	COG0346	lactoylglutathione lyase activity
KHC17_13135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_13140	COG3443	Belongs to the bacterial solute-binding protein 9 family
KHC17_13145	COG0668	transmembrane transport
KHC17_13155	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KHC17_13160	COG0354	folic acid binding
KHC17_13185	COG1742	UPF0060 membrane protein
KHC17_13200	COG1183	phosphatidylcholine synthase activity
KHC17_13205	COG0688	phosphatidylethanolamine metabolic process
KHC17_13210	COG5265	(ABC) transporter
KHC17_13255	COG2852	Protein conserved in bacteria
KHC17_13260	COG0215	cysteine-tRNA ligase activity
KHC17_13265	COG4221	oxidoreductase activity
KHC17_13270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHC17_13275	COG1286	toxin biosynthetic process
KHC17_13295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHC17_13305	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KHC17_13315	COG0305	Participates in initiation and elongation during chromosome replication
KHC17_13335	COG0359	binds to the 23S rRNA
KHC17_13345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHC17_13350	COG0360	Binds together with S18 to 16S ribosomal RNA
KHC17_13355	COG0667	Aldo Keto reductase
KHC17_13360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHC17_13370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHC17_13375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHC17_13380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHC17_13385	COG1561	YicC-like family, N-terminal region
KHC17_13390	COG0194	GDP metabolic process
KHC17_13395	COG0400	carboxylic ester hydrolase activity
KHC17_13400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHC17_13430	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHC17_13445	COG2203	Gaf domain
KHC17_13445	COG3706	GGDEF domain
KHC17_13445	COG4251	negative regulation of phosphorylation
KHC17_13445	COG5001	Diguanylate cyclase
KHC17_13450	COG3300	MHYT domain
KHC17_13450	COG5001	Diguanylate cyclase
KHC17_13455	COG0488	(ABC) transporter
KHC17_13460	COG3706	GGDEF domain
KHC17_13470	COG0105	UTP biosynthetic process
KHC17_13490	COG0314	molybdopterin synthase activity
KHC17_13500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHC17_13505	COG0322	excinuclease ABC activity
KHC17_13510	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_13520	COG0625	glutathione transferase activity
KHC17_13535	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KHC17_13540	COG0243	molybdopterin cofactor binding
KHC17_13555	COG4571	Outer membrane protease
KHC17_13560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHC17_13565	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KHC17_13575	COG0628	permease
KHC17_13585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHC17_13590	COG0248	Ppx GppA phosphatase
KHC17_13615	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
KHC17_13620	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KHC17_13625	COG0477	Major facilitator Superfamily
KHC17_13630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHC17_13640	COG4452	Inner membrane protein CreD
KHC17_13645	COG0659	secondary active sulfate transmembrane transporter activity
KHC17_13655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHC17_13660	COG3654	unkown
KHC17_13665	COG2336	PFAM SpoVT AbrB
KHC17_13670	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KHC17_13680	COG0113	porphobilinogen synthase activity
KHC17_13700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHC17_13705	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHC17_13710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHC17_13710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KHC17_13720	COG1280	lysine exporter protein (LysE YggA)
KHC17_13725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KHC17_13730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHC17_13735	COG2814	Major facilitator Superfamily
KHC17_13740	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KHC17_13760	COG0416	fatty acid biosynthetic process
KHC17_13765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KHC17_13770	COG0776	regulation of translation
KHC17_13805	COG0601	transmembrane transport
KHC17_13810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_13815	COG0444	Belongs to the ABC transporter superfamily
KHC17_13835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KHC17_13840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KHC17_13855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHC17_13860	COG0583	DNA-binding transcription factor activity
KHC17_13870	COG0737	Belongs to the 5'-nucleotidase family
KHC17_13890	COG2897	thiosulfate sulfurtransferase activity
KHC17_13905	COG0415	Belongs to the DNA photolyase family
KHC17_13915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHC17_13945	COG3932	Exopolysaccharide synthesis, ExoD
KHC17_13950	COG1238	metal cluster binding
KHC17_13965	COG4139	cobalamin transport
KHC17_13970	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KHC17_13980	COG1528	Iron-storage protein
KHC17_14025	COG0297	glycogen (starch) synthase activity
KHC17_14050	COG1612	heme a metabolic process
KHC17_14060	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHC17_14065	COG0010	Belongs to the arginase family
KHC17_14070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KHC17_14075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHC17_14085	COG1832	CoA-binding protein
KHC17_14110	COG0740	serine-type endopeptidase activity
KHC17_14115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHC17_14120	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KHC17_14130	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KHC17_14160	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHC17_14165	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHC17_14170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHC17_14180	COG0649	NAD binding
KHC17_14190	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KHC17_14195	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KHC17_14205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KHC17_14210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KHC17_14220	COG0713	ATP synthesis coupled electron transport
KHC17_14235	COG1007	ATP synthesis coupled electron transport
KHC17_14240	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KHC17_14240	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KHC17_14255	COG0442	prolyl-tRNA aminoacylation
KHC17_14265	COG1136	(ABC) transporter
KHC17_14280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHC17_14290	COG0784	Response regulator, receiver
KHC17_14300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KHC17_14305	COG0477	Major facilitator Superfamily
KHC17_14320	COG0557	exoribonuclease II activity
KHC17_14325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHC17_14335	COG0758	DNA mediated transformation
KHC17_14340	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KHC17_14350	COG0540	Belongs to the ATCase OTCase family
KHC17_14360	COG1960	acyl-CoA dehydrogenase activity
KHC17_14365	COG0456	acetyltransferase
KHC17_14395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHC17_14400	COG2824	Alkylphosphonate utilization operon protein PhnA
KHC17_14405	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KHC17_14410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHC17_14415	COG0154	amidase activity
KHC17_14420	COG0456	acetyltransferase
KHC17_14425	COG3811	Belongs to the UPF0386 family
KHC17_14440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHC17_14450	COG0456	acetyltransferase
KHC17_14465	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KHC17_14470	COG0439	Biotin carboxylase
KHC17_14475	COG0511	ligase activity, forming carbon-carbon bonds
KHC17_14480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHC17_14490	COG0436	Aminotransferase
KHC17_14510	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_14515	COG1530	ribonuclease E activity
KHC17_14525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KHC17_14545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHC17_14550	COG0384	phenazine biosynthesis protein PhzF
KHC17_14570	COG0633	Ferredoxin
KHC17_14580	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHC17_14585	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHC17_14590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KHC17_14600	COG3768	UPF0283 membrane protein
KHC17_14605	COG3106	COG3106 Predicted ATPase
KHC17_14635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KHC17_14665	COG0537	adenosine 5'-monophosphoramidase activity
KHC17_14690	COG0052	Belongs to the universal ribosomal protein uS2 family
KHC17_14695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHC17_14700	COG0528	UMP kinase activity
KHC17_14705	COG0233	cytoplasmic translational termination
KHC17_14710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHC17_14720	COG0750	zinc metalloprotease
KHC17_14725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHC17_14730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHC17_14735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHC17_14740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHC17_14745	COG3494	Protein of unknown function (DUF1009)
KHC17_14750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KHC17_14755	COG2186	Transcriptional regulator
KHC17_14765	COG0765	amino acid transport
KHC17_14770	COG0765	amino acid transport
KHC17_14780	COG0372	Belongs to the citrate synthase family
KHC17_14795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHC17_14815	COG0683	leucine binding
KHC17_14820	COG1960	acyl-CoA dehydrogenase activity
KHC17_14835	COG1024	Enoyl-CoA hydratase
KHC17_14850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHC17_14870	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KHC17_14875	COG0148	phosphopyruvate hydratase activity
KHC17_14885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KHC17_14890	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHC17_14890	COG0022	dehydrogenase e1 component
KHC17_14895	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHC17_14905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHC17_14915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KHC17_14920	COG0697	spore germination
KHC17_14940	COG2867	negative regulation of translational initiation
KHC17_14945	COG1546	Belongs to the CinA family
KHC17_14950	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KHC17_14950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KHC17_14960	COG3852	Histidine kinase
KHC17_14965	COG2204	response regulator
KHC17_14970	COG5000	phosphorelay sensor kinase activity
KHC17_14975	COG2204	response regulator
KHC17_14980	COG0569	domain protein
KHC17_14985	COG1923	regulation of RNA biosynthetic process
KHC17_14990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHC17_14995	COG3956	TIGRFAM MazG family protein
KHC17_15005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KHC17_15005	COG1648	precorrin-2 dehydrogenase activity
KHC17_15045	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHC17_15045	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHC17_15050	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHC17_15050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KHC17_15055	COG0509	glycine decarboxylation via glycine cleavage system
KHC17_15060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KHC17_15085	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHC17_15110	COG0251	oxidation-reduction process
KHC17_15115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KHC17_15125	COG1671	Belongs to the UPF0178 family
KHC17_15150	COG2801	Transposase and inactivated derivatives
KHC17_15155	COG0431	NADPH-dependent FMN reductase
KHC17_15165	COG0798	PFAM Bile acid sodium symporter
KHC17_15170	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHC17_15180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHC17_15180	COG3320	Male sterility
KHC17_15185	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_15190	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KHC17_15195	COG2070	2-Nitropropane dioxygenase
KHC17_15195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KHC17_15205	COG3321	synthase
KHC17_15205	COG0604	alcohol dehydrogenase
KHC17_15210	COG0604	alcohol dehydrogenase
KHC17_15210	COG3321	synthase
KHC17_15250	COG0321	lipoyl(octanoyl) transferase activity
KHC17_15250	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KHC17_15255	COG0084	hydrolase, TatD family'
KHC17_15260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHC17_15270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHC17_15325	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHC17_15330	COG2095	MarC family integral membrane protein
KHC17_15335	COG0517	IMP dehydrogenase activity
KHC17_15335	COG0617	tRNA 3'-terminal CCA addition
KHC17_15335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KHC17_15340	COG0629	single-stranded DNA binding
KHC17_15345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHC17_15375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KHC17_15380	COG1121	(ABC) transporter
KHC17_15400	COG0667	Aldo Keto reductase
KHC17_15410	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHC17_15490	COG2239	Acts as a magnesium transporter
KHC17_15495	COG0243	molybdopterin cofactor binding
KHC17_15505	COG0242	peptide deformylase activity
KHC17_15525	COG2202	Pas domain
KHC17_15525	COG2205	protein histidine kinase activity
KHC17_15535	COG0321	lipoyl(octanoyl) transferase activity
KHC17_15540	COG1064	alcohol dehydrogenase
KHC17_15570	COG1862	Preprotein translocase
KHC17_15585	COG1309	transcriptional regulator
KHC17_15590	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHC17_15590	COG2124	cytochrome p450
KHC17_15605	COG0596	Alpha beta hydrolase
KHC17_15615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHC17_15620	COG0626	cystathionine gamma-synthase activity
KHC17_15625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_15630	COG4597	amino acid ABC transporter
KHC17_15635	COG0765	amino acid transport
KHC17_15640	COG1126	abc transporter atp-binding protein
KHC17_15655	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KHC17_15670	COG0436	Aminotransferase
KHC17_15700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KHC17_15710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHC17_15715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHC17_15720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KHC17_15735	COG3243	poly(R)-hydroxyalkanoic acid synthase
KHC17_15740	COG1489	DNA binding
KHC17_15745	COG0024	Methionine aminopeptidase
KHC17_15750	COG2003	Belongs to the UPF0758 family
KHC17_15765	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KHC17_15780	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHC17_15785	COG0546	phosphoglycolate phosphatase activity
KHC17_15795	COG0114	fumarate hydratase activity
KHC17_15805	COG0504	CTP synthase activity
KHC17_15815	COG0149	triose-phosphate isomerase activity
KHC17_15825	COG0187	DNA topoisomerase II activity
KHC17_15835	COG0740	serine-type endopeptidase activity
KHC17_15845	COG0640	Transcriptional regulator
KHC17_15925	COG1127	ABC transporter
KHC17_15930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KHC17_15935	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_15945	COG0280	phosphate acetyltransferase
KHC17_15945	COG0281	malic enzyme
KHC17_15955	COG0778	Nitroreductase
KHC17_15960	COG0823	Involved in the tonB-independent uptake of proteins
KHC17_15975	COG1368	sulfuric ester hydrolase activity
KHC17_16000	COG0544	peptidyl-prolyl cis-trans isomerase activity
KHC17_16020	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHC17_16025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KHC17_16040	COG0318	PFAM AMP-dependent synthetase and ligase
KHC17_16050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHC17_16050	COG0512	Glutamine amidotransferase of anthranilate synthase
KHC17_16055	COG0343	queuine tRNA-ribosyltransferase activity
KHC17_16060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KHC17_16075	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHC17_16090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHC17_16095	COG0134	indole-3-glycerol-phosphate synthase activity
KHC17_16100	COG0315	cyclic pyranopterin monophosphate synthase activity
KHC17_16105	COG0303	'Molybdopterin
KHC17_16110	COG3706	GGDEF domain
KHC17_16120	COG0475	glutathione-regulated potassium exporter activity
KHC17_16120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHC17_16130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KHC17_16135	COG0697	spore germination
KHC17_16140	COG2814	Major facilitator Superfamily
KHC17_16145	COG0746	molybdenum cofactor guanylyltransferase activity
KHC17_16150	COG1763	Mo-molybdopterin cofactor biosynthetic process
KHC17_16155	COG0739	heme binding
KHC17_16160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KHC17_16165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KHC17_16170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHC17_16175	COG0805	protein transport
KHC17_16180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHC17_16185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KHC17_16190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHC17_16195	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHC17_16200	COG1472	Belongs to the glycosyl hydrolase 3 family
KHC17_16210	COG0018	arginyl-trna synthetase
KHC17_16215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KHC17_16240	COG0525	valine-tRNA ligase activity
KHC17_16250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KHC17_16280	COG0655	NAD(P)H dehydrogenase (quinone) activity
KHC17_16285	COG1546	Belongs to the CinA family
KHC17_16285	COG1058	Belongs to the CinA family
KHC17_16290	COG0589	response to stress
KHC17_16295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KHC17_16300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHC17_16350	COG1914	H( )-stimulated, divalent metal cation uptake system
KHC17_16360	COG1132	(ABC) transporter
KHC17_16365	COG0628	permease
KHC17_16385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHC17_16400	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHC17_16410	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KHC17_16420	COG0302	gtp cyclohydrolase
KHC17_16425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHC17_16430	COG1752	Esterase of the alpha-beta hydrolase superfamily
KHC17_16435	COG0516	GMP reductase activity
KHC17_16435	COG0517	IMP dehydrogenase activity
KHC17_16470	COG1760	l-serine dehydratase
KHC17_16485	COG3698	Phosphodiester glycosidase
KHC17_16505	COG0583	DNA-binding transcription factor activity
KHC17_16520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHC17_16520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KHC17_16525	COG0347	Belongs to the P(II) protein family
KHC17_16530	COG0174	glutamine synthetase
KHC17_16560	COG0697	spore germination
KHC17_16570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHC17_16580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHC17_16590	COG3668	Plasmid stabilization system
KHC17_16595	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KHC17_16610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHC17_16615	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHC17_16620	COG2186	Transcriptional regulator
KHC17_16630	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHC17_16635	COG4603	Belongs to the binding-protein-dependent transport system permease family
KHC17_16640	COG3845	ABC transporter
KHC17_16645	COG1183	phosphatidylcholine synthase activity
KHC17_16650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHC17_16655	COG0679	Auxin Efflux Carrier
KHC17_16660	COG0785	Cytochrome C biogenesis protein
KHC17_16680	COG1278	Cold shock
KHC17_16735	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KHC17_16745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHC17_16925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHC17_16995	COG1061	Type III restriction enzyme res subunit
KHC17_17105	COG0582	viral genome integration into host DNA
KHC17_17125	COG0577	efflux transmembrane transporter activity
KHC17_17125	COG1136	(ABC) transporter
KHC17_17130	COG0577	efflux transmembrane transporter activity
KHC17_17130	COG1136	(ABC) transporter
KHC17_17140	COG2151	metal-sulfur cluster biosynthetic enzyme
KHC17_17145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHC17_17150	COG0719	Fe-S assembly protein
KHC17_17155	COG0396	ATPase activity
KHC17_17160	COG0719	Fe-S assembly protein
KHC17_17165	COG1104	cysteine desulfurase activity
KHC17_17170	COG2945	thiolester hydrolase activity
KHC17_17175	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KHC17_17180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHC17_17190	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KHC17_17195	COG2833	Protein of unknown function (DUF455)
KHC17_17200	COG0739	heme binding
KHC17_17205	COG0513	Belongs to the DEAD box helicase family
KHC17_17235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHC17_17245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KHC17_17250	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHC17_17255	COG0047	phosphoribosylformylglycinamidine synthase activity
KHC17_17270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHC17_17280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHC17_17300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KHC17_17305	COG2814	Major facilitator Superfamily
KHC17_17310	COG0483	inositol monophosphate 1-phosphatase activity
KHC17_17315	COG0483	inositol monophosphate 1-phosphatase activity
KHC17_17320	COG0037	tRNA processing
KHC17_17325	COG2066	Belongs to the glutaminase family
KHC17_17330	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHC17_17335	COG0861	Integral membrane protein TerC family
KHC17_17355	COG1280	lysine exporter protein (LysE YggA)
KHC17_17365	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KHC17_17370	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KHC17_17380	COG0538	isocitrate dehydrogenase activity
KHC17_17395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHC17_17400	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHC17_17410	COG2313	pseudouridylate synthase activity
KHC17_17420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_17425	COG4215	(ABC) transporter
KHC17_17435	COG5425	PFAM Usg family protein
KHC17_17445	COG1522	sequence-specific DNA binding
KHC17_17450	COG1573	uracil-dna glycosylase
KHC17_17460	COG2205	protein histidine kinase activity
KHC17_17460	COG2202	Pas domain
KHC17_17470	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KHC17_17475	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KHC17_17495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KHC17_17500	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_17505	COG1129	ABC transporter
KHC17_17515	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_17520	COG3959	Transketolase, thiamine diphosphate binding domain
KHC17_17525	COG3958	Transketolase
KHC17_17530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHC17_17535	COG2390	Transcriptional regulator
KHC17_17545	COG0842	Transport permease protein
KHC17_17550	COG1131	(ABC) transporter
KHC17_17555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHC17_17555	COG0730	response to heat
KHC17_17575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KHC17_17580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KHC17_17600	COG0129	dihydroxy-acid dehydratase activity
KHC17_17605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KHC17_17610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KHC17_17615	COG0203	ribosomal protein L17
KHC17_17620	COG0202	RNA polymerase activity
KHC17_17625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHC17_17630	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHC17_17635	COG0563	adenylate kinase activity
KHC17_17640	COG0201	protein transport
KHC17_17650	COG0200	Binds to the 23S rRNA
KHC17_17655	COG1841	ribosomal large subunit assembly
KHC17_17660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHC17_17665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHC17_17670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHC17_17675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHC17_17680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHC17_17685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHC17_17690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHC17_17695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHC17_17700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHC17_17705	COG0255	Belongs to the universal ribosomal protein uL29 family
KHC17_17710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHC17_17715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHC17_17720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHC17_17725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHC17_17730	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHC17_17735	COG0089	rRNA binding
KHC17_17740	COG0088	Forms part of the polypeptide exit tunnel
KHC17_17745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHC17_17750	COG0051	transcription antitermination factor activity, RNA binding
KHC17_17755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHC17_17760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHC17_17765	COG0049	tRNA binding
KHC17_17770	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHC17_17790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHC17_17795	COG0085	RNA polymerase activity
KHC17_17800	COG0222	ribosome binding
KHC17_17805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHC17_17810	COG0081	regulation of translation
KHC17_17815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHC17_17825	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KHC17_17835	COG1086	Polysaccharide biosynthesis protein
KHC17_17840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHC17_17845	COG0861	Integral membrane protein TerC family
KHC17_17850	COG3895	Periplasmic Protein
KHC17_17885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHC17_17890	COG1607	acyl-coa hydrolase
KHC17_17910	COG2910	NAD(P)H-binding
KHC17_17915	COG1733	regulation of RNA biosynthetic process
KHC17_17920	COG0556	nucleotide-excision repair
KHC17_17925	COG2382	esterase
KHC17_17945	COG0484	heat shock protein binding
KHC17_17965	COG3706	GGDEF domain
KHC17_17975	COG3842	ATPase activity
KHC17_17985	COG1840	ABC-type Fe3 transport system, periplasmic component
KHC17_17990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHC17_18005	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHC17_18015	COG2207	Transcriptional regulator
KHC17_18020	COG1064	alcohol dehydrogenase
KHC17_18025	COG1252	NADH dehydrogenase
KHC17_18030	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KHC17_18040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHC17_18045	COG0702	epimerase
KHC17_18085	COG0656	L-ascorbic acid biosynthetic process
KHC17_18100	COG0440	acetolactate synthase activity
KHC17_18105	COG0028	Belongs to the TPP enzyme family
KHC17_18115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHC17_18120	COG0560	Phosphoserine phosphatase
KHC17_18120	COG3830	Belongs to the UPF0237 family
KHC17_18130	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_18140	COG0330	HflC and HflK could
KHC17_18145	COG0330	HflC and HflK could
KHC17_18155	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHC17_18190	COG0277	FAD linked oxidase domain protein
KHC17_18195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHC17_18250	COG1335	isochorismatase
KHC17_18280	COG2264	protein methyltransferase activity
KHC17_18285	COG1999	signal sequence binding
KHC17_18295	COG0835	chemotaxis
KHC17_18310	COG0583	DNA-binding transcription factor activity
KHC17_18320	COG1247	-acetyltransferase
KHC17_18330	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHC17_18335	COG0497	DNA recombination
KHC17_18340	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KHC17_18350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHC17_18355	COG0849	cell division
KHC17_18360	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KHC17_18365	COG1181	Belongs to the D-alanine--D-alanine ligase family
KHC17_18370	COG0477	Major facilitator Superfamily
KHC17_18375	COG5001	Diguanylate cyclase
KHC17_18375	COG3300	MHYT domain
KHC17_18385	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KHC17_18390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KHC17_18395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHC17_18405	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHC17_18410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHC17_18420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHC17_18435	COG0275	rRNA processing
KHC17_18440	COG2001	Belongs to the MraZ family
KHC17_18465	COG3023	N-Acetylmuramoyl-L-alanine amidase
KHC17_18495	COG4106	trans-aconitate 2-methyltransferase activity
KHC17_18515	COG2226	methyltransferase
KHC17_18525	COG2267	carboxylic ester hydrolase activity
KHC17_18530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KHC17_18560	COG1376	ErfK ybiS ycfS ynhG family protein
KHC17_18565	COG2814	Major facilitator Superfamily
KHC17_18585	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_18590	COG0174	glutamine synthetase
KHC17_18595	COG0531	amino acid
KHC17_18605	COG1737	Transcriptional regulator
KHC17_18610	COG1840	ABC-type Fe3 transport system, periplasmic component
KHC17_18625	COG3842	ATPase activity
KHC17_18740	COG2968	Membrane
KHC17_18750	COG0432	Pfam Uncharacterised protein family UPF0047
KHC17_18765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHC17_18770	COG0358	DNA primase activity
KHC17_18780	COG0505	Belongs to the CarA family
KHC17_18785	COG0534	Mate efflux family protein
KHC17_18800	COG2321	neutral zinc metallopeptidase
KHC17_18815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KHC17_18825	COG3706	GGDEF domain
KHC17_18840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KHC17_18850	COG1522	sequence-specific DNA binding
KHC17_18855	COG0492	ferredoxin-NADP+ reductase activity
KHC17_18860	COG0583	DNA-binding transcription factor activity
KHC17_18870	COG1902	pentaerythritol trinitrate reductase activity
KHC17_18895	COG0387	Pfam Sodium calcium exchanger
KHC17_18900	COG0436	Aminotransferase
KHC17_18905	COG2199	diguanylate cyclase activity
KHC17_18905	COG2200	EAL domain
KHC17_18920	COG1278	Cold shock
KHC17_18925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHC17_18935	COG1846	Transcriptional regulator
KHC17_18940	COG0745	RESPONSE REGULATOR receiver
KHC17_18950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHC17_18970	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHC17_18980	COG1496	oxidoreductase activity
KHC17_18995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHC17_19020	COG0840	transmembrane signaling receptor activity
KHC17_19025	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_19035	COG5001	Diguanylate cyclase
KHC17_19035	COG3300	MHYT domain
KHC17_19040	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHC17_19045	COG5001	Diguanylate cyclase
KHC17_19055	COG0193	aminoacyl-tRNA hydrolase activity
KHC17_19065	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KHC17_19085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHC17_19090	COG2857	Cytochrome c1
KHC17_19090	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KHC17_19110	COG1132	(ABC) transporter
KHC17_19115	COG1132	(ABC) transporter
KHC17_19120	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KHC17_19135	COG0408	coproporphyrinogen oxidase activity
KHC17_19150	COG0617	tRNA 3'-terminal CCA addition
KHC17_19155	COG0494	nUDIX hydrolase
KHC17_19165	COG0714	Associated with various cellular activities
KHC17_19185	COG0454	-acetyltransferase
KHC17_19200	COG0477	Major facilitator Superfamily
KHC17_19210	COG0435	Glutathione S-transferase
KHC17_19215	COG0494	nUDIX hydrolase
KHC17_19225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHC17_19240	COG3135	benzoate transporter
KHC17_19260	COG0740	serine-type endopeptidase activity
KHC17_19275	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KHC17_19280	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHC17_19305	COG4175	Glycine betaine
KHC17_19325	COG1435	thymidine kinase activity
KHC17_19345	COG2862	Uncharacterized protein family, UPF0114
KHC17_19360	COG0512	Glutamine amidotransferase of anthranilate synthase
KHC17_19360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHC17_19375	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KHC17_19390	COG0366	Alpha amylase catalytic
KHC17_19395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_19410	COG1160	GTP binding
KHC17_19430	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KHC17_19440	COG0024	Methionine aminopeptidase
KHC17_19450	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_19460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KHC17_19470	COG0583	DNA-binding transcription factor activity
KHC17_19485	COG0402	S-adenosylhomocysteine deaminase activity
KHC17_19505	COG1309	transcriptional regulator
KHC17_19510	COG1686	Belongs to the peptidase S11 family
KHC17_19520	COG2351	hydroxyisourate hydrolase activity
KHC17_19525	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KHC17_19550	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KHC17_19560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_19560	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KHC17_19570	COG0513	Belongs to the DEAD box helicase family
KHC17_19580	COG2259	Doxx family
KHC17_19585	COG1376	ErfK ybiS ycfS ynhG family protein
KHC17_19600	COG2308	Evidence 4 Homologs of previously reported genes of
KHC17_19610	COG1305	Transglutaminase-like
KHC17_19640	COG4214	carbohydrate transport
KHC17_19650	COG4213	ABC transporter substrate-binding protein
KHC17_19695	COG0840	transmembrane signaling receptor activity
KHC17_19700	COG2814	Major facilitator Superfamily
KHC17_19705	COG1410	methionine synthase
KHC17_19705	COG0646	methionine synthase
KHC17_19715	COG4215	(ABC) transporter
KHC17_19745	COG1215	transferase activity, transferring glycosyl groups
KHC17_19775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHC17_19790	COG2346	COG2346, Truncated hemoglobins
KHC17_19810	COG1309	transcriptional regulator
KHC17_19830	COG0494	nUDIX hydrolase
KHC17_19840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_19845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_19855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_19870	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KHC17_19875	COG0830	nickel cation binding
KHC17_19880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KHC17_19895	COG0804	urea catabolic process
KHC17_19900	COG1442	glycosyl transferase family 8
KHC17_19905	COG3755	Protein conserved in bacteria
KHC17_19915	COG0832	Belongs to the urease beta subunit family
KHC17_19920	COG0831	urea catabolic process
KHC17_19925	COG0829	nickel cation binding
KHC17_19950	COG0559	Belongs to the binding-protein-dependent transport system permease family
KHC17_19965	COG0174	glutamine synthetase
KHC17_19970	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_19975	COG0784	Response regulator, receiver
KHC17_19975	COG2198	Histidine kinase
KHC17_19975	COG5002	protein histidine kinase activity
KHC17_20020	COG1218	3'(2'),5'-bisphosphate nucleotidase
KHC17_20065	COG1846	Transcriptional regulator
KHC17_20100	COG0564	pseudouridine synthase activity
KHC17_20110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KHC17_20120	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHC17_20145	COG0346	lactoylglutathione lyase activity
KHC17_20155	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHC17_20165	COG2832	Protein of unknown function (DUF454)
KHC17_20170	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KHC17_20175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_20180	COG4558	Periplasmic binding protein
KHC17_20190	COG3721	Heme iron utilization protein
KHC17_20205	COG2205	protein histidine kinase activity
KHC17_20245	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KHC17_20250	COG4605	iron ion homeostasis
KHC17_20255	COG4604	ABC transporter, ATP-binding protein
KHC17_20260	COG0783	Belongs to the Dps family
KHC17_20285	COG2814	Major facilitator Superfamily
KHC17_20295	COG0583	DNA-binding transcription factor activity
KHC17_20300	COG0657	acetylesterase activity
KHC17_20305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_20325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHC17_20330	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
KHC17_20335	COG0288	reversible hydration of carbon dioxide
KHC17_20345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHC17_20360	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KHC17_20365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KHC17_20370	COG0778	Nitroreductase
KHC17_20375	COG2267	carboxylic ester hydrolase activity
KHC17_20380	COG0251	oxidation-reduction process
KHC17_20385	COG1335	isochorismatase
KHC17_20390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KHC17_20400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_20415	COG1175	transmembrane transport
KHC17_20420	COG0395	ABC-type sugar transport system, permease component
KHC17_20425	COG3842	ATPase activity
KHC17_20430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_20440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KHC17_20455	COG4608	Belongs to the ABC transporter superfamily
KHC17_20460	COG0444	Belongs to the ABC transporter superfamily
KHC17_20465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_20470	COG0601	transmembrane transport
KHC17_20525	COG2159	amidohydrolase
KHC17_20530	COG1960	acyl-CoA dehydrogenase activity
KHC17_20555	COG0450	alkyl hydroperoxide reductase
KHC17_20580	COG0745	RESPONSE REGULATOR receiver
KHC17_20590	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHC17_20590	COG1902	pentaerythritol trinitrate reductase activity
KHC17_20595	COG3842	ATPase activity
KHC17_20605	COG1840	ABC-type Fe3 transport system, periplasmic component
KHC17_20610	COG1840	ABC-type Fe3 transport system, periplasmic component
KHC17_20615	COG0745	RESPONSE REGULATOR receiver
KHC17_20625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHC17_20630	COG0583	DNA-binding transcription factor activity
KHC17_20665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KHC17_20675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_20680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KHC17_20690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHC17_20715	COG0583	DNA-binding transcription factor activity
KHC17_20720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_20725	COG0725	ABC transporter, periplasmic molybdate-binding protein
KHC17_20730	COG4149	molybdate abc transporter
KHC17_20735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KHC17_20750	COG2022	thiamine diphosphate biosynthetic process
KHC17_20765	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KHC17_20770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHC17_20780	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHC17_20800	COG1132	(ABC) transporter
KHC17_20805	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHC17_20805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHC17_20850	COG4166	transmembrane transport
KHC17_20860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_20870	COG0438	transferase activity, transferring glycosyl groups
KHC17_20875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHC17_20880	COG3142	Participates in the control of copper homeostasis
KHC17_20885	COG2814	Major facilitator Superfamily
KHC17_20900	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_20905	COG1737	Transcriptional regulator
KHC17_20915	COG3842	ATPase activity
KHC17_20925	COG0395	ABC-type sugar transport system, permease component
KHC17_20945	COG2188	Transcriptional regulator
KHC17_20950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KHC17_20955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHC17_20960	COG1940	carbohydrate kinase activity
KHC17_20970	COG0671	phosphoesterase, PA-phosphatase related
KHC17_20975	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KHC17_20980	COG0156	8-amino-7-oxononanoate synthase activity
KHC17_20990	COG0729	surface antigen
KHC17_21000	COG0835	chemotaxis
KHC17_21010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KHC17_21015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KHC17_21020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHC17_21025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHC17_21030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHC17_21035	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHC17_21050	COG4974	Belongs to the 'phage' integrase family
KHC17_21075	COG1280	lysine exporter protein (LysE YggA)
KHC17_21085	COG0508	dehydrogenase complex catalyzes the overall conversion of
KHC17_21090	COG0567	Dehydrogenase, E1 component
KHC17_21095	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHC17_21100	COG0045	succinate-CoA ligase (ADP-forming) activity
KHC17_21105	COG0039	L-malate dehydrogenase activity
KHC17_21110	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KHC17_21150	COG2264	protein methyltransferase activity
KHC17_21165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KHC17_21170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHC17_21175	COG0181	hydroxymethylbilane synthase activity
KHC17_21215	COG1872	DUF167
KHC17_21220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KHC17_21230	COG1217	gtp-binding protein TYPA
KHC17_21235	COG0339	signal peptide processing
KHC17_21245	COG1846	Transcriptional regulator
KHC17_21255	COG0137	argininosuccinate synthase activity
KHC17_21265	COG1280	lysine exporter protein (LysE YggA)
KHC17_21275	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KHC17_21280	COG4120	Belongs to the binding-protein-dependent transport system permease family
KHC17_21290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KHC17_21305	COG2154	pterin-4-alpha-carbinolamine dehydratase
KHC17_21310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHC17_21315	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KHC17_21325	COG4181	ATPase activity
KHC17_21335	COG0670	Belongs to the BI1 family
KHC17_21350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHC17_21355	COG4133	protoheme IX ABC transporter activity
KHC17_21360	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHC17_21365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KHC17_21390	COG2917	probably involved in intracellular septation
KHC17_21395	COG0552	protein localization to endoplasmic reticulum
KHC17_21400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHC17_21405	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHC17_21415	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHC17_21420	COG0287	Prephenate dehydrogenase
KHC17_21420	COG1605	Chorismate mutase
KHC17_21425	COG0228	four-way junction DNA binding
KHC17_21430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHC17_21435	COG0336	Belongs to the RNA methyltransferase TrmD family
KHC17_21445	COG0335	large ribosomal subunit rRNA binding
KHC17_21450	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KHC17_21455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_21475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHC17_21485	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KHC17_21505	COG0488	(ABC) transporter
KHC17_21515	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KHC17_21525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KHC17_21530	COG0142	geranyltranstransferase activity
KHC17_21535	COG2885	chlorophyll binding
KHC17_21540	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHC17_21545	COG2223	nitrite transmembrane transporter activity
KHC17_21555	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KHC17_21560	COG2197	response regulator
KHC17_21565	COG1132	(ABC) transporter
KHC17_21575	COG3459	Glycosyltransferase 36 associated
KHC17_21580	COG1473	amidohydrolase
KHC17_21590	COG0579	oxidoreductase
KHC17_21600	COG0129	dihydroxy-acid dehydratase activity
KHC17_21605	COG2084	Dehydrogenase
KHC17_21610	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KHC17_21615	COG0277	FAD linked oxidase domain protein
KHC17_21620	COG2186	Transcriptional regulator
KHC17_21630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KHC17_21635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KHC17_21640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_21645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KHC17_21660	COG0495	leucyl-tRNA aminoacylation
KHC17_21675	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KHC17_21680	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHC17_21690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KHC17_21695	COG1946	Acyl-CoA thioesterase
KHC17_21700	COG0347	Belongs to the P(II) protein family
KHC17_21705	COG0004	ammonium transporteR
KHC17_21720	COG1674	ftsk spoiiie
KHC17_21725	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KHC17_21740	COG0745	RESPONSE REGULATOR receiver
KHC17_21750	COG1329	Transcriptional regulator
KHC17_21760	COG2270	Major facilitator Superfamily
KHC17_21770	COG0183	Belongs to the thiolase family
KHC17_21775	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_21790	COG0494	nUDIX hydrolase
KHC17_21795	COG2861	carbohydrate metabolic process
KHC17_21800	COG0793	Belongs to the peptidase S41A family
KHC17_21810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHC17_21815	COG0799	negative regulation of ribosome biogenesis
KHC17_21820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHC17_21825	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHC17_21830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHC17_21835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHC17_21850	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KHC17_21855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KHC17_21870	COG2301	Belongs to the HpcH HpaI aldolase family
KHC17_21880	COG0066	3-isopropylmalate dehydratase activity
KHC17_21885	COG0473	3-isopropylmalate dehydrogenase activity
KHC17_21890	COG1858	cytochrome C peroxidase
KHC17_21895	COG1797	cobyrinic acid a,c-diamide synthase activity
KHC17_21905	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KHC17_21970	COG1492	cobalamin metabolic process
KHC17_21985	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_21990	COG3254	rhamnose metabolic process
KHC17_22000	COG1063	alcohol dehydrogenase
KHC17_22025	COG1129	ABC transporter
KHC17_22030	COG2186	Transcriptional regulator
KHC17_22035	COG2721	sulfolactate sulfo-lyase activity
KHC17_22045	COG0138	bifunctional purine biosynthesis protein purh
KHC17_22055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHC17_22055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHC17_22060	COG0501	Belongs to the peptidase M48B family
KHC17_22085	COG0357	Ribosomal RNA small subunit methyltransferase G
KHC17_22090	COG0445	tRNA wobble uridine modification
KHC17_22095	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHC17_22100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHC17_22105	COG1981	membrane
KHC17_22110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KHC17_22115	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KHC17_22120	COG0424	maF-like protein
KHC17_22125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHC17_22130	COG0237	dephospho-CoA kinase activity
KHC17_22140	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KHC17_22145	COG3030	protein affecting phage T7 exclusion by the F plasmid
KHC17_22155	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KHC17_22180	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHC17_22195	COG0135	phosphoribosylanthranilate isomerase activity
KHC17_22200	COG0133	tryptophan synthase activity
KHC17_22205	COG0159	tryptophan synthase activity
KHC17_22210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KHC17_22225	COG1074	ATP-dependent DNA helicase activity
KHC17_22235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KHC17_22245	COG2205	protein histidine kinase activity
KHC17_22250	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KHC17_22255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHC17_22260	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
KHC17_22260	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHC17_22265	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHC17_22270	COG0642	Histidine kinase
KHC17_22275	COG0745	RESPONSE REGULATOR receiver
KHC17_22280	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KHC17_22290	COG1652	LysM domain
KHC17_22295	COG1072	(Pantothenic acid kinase))
KHC17_22300	COG0140	phosphoribosyl-ATP diphosphatase activity
KHC17_22305	COG0107	imidazoleglycerol-phosphate synthase activity
KHC17_22310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KHC17_22315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHC17_22325	COG0131	Imidazoleglycerol-phosphate dehydratase
KHC17_22330	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHC17_22335	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHC17_22345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KHC17_22360	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
KHC17_22370	COG1643	Atp-dependent helicase
KHC17_22405	COG0514	ATP-dependent DNA helicase (RecQ)
KHC17_22430	COG1072	(Pantothenic acid kinase))
KHC17_22440	COG1780	Probably involved in ribonucleotide reductase function
KHC17_22460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHC17_22485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHC17_22500	COG1185	polyribonucleotide nucleotidyltransferase activity
KHC17_22505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHC17_22510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHC17_22515	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHC17_22520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHC17_22520	COG3064	Membrane
KHC17_22535	COG0779	Required for maturation of 30S ribosomal subunits
KHC17_22540	COG2814	Major facilitator Superfamily
KHC17_22545	COG2951	lytic endotransglycosylase activity
KHC17_22550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHC17_22560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHC17_22565	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHC17_22580	COG2816	NAD+ diphosphatase activity
KHC17_22585	COG0077	Prephenate dehydratase
KHC17_22585	COG1605	Chorismate mutase
KHC17_22590	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KHC17_22595	COG3474	cytochrome
KHC17_22605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KHC17_22610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHC17_22615	COG1278	Cold shock
KHC17_22620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KHC17_22630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHC17_22630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHC17_22640	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KHC17_22670	COG2900	Belongs to the SlyX family
KHC17_22680	COG0484	heat shock protein binding
KHC17_22685	COG0443	Heat shock 70 kDa protein
KHC17_22700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHC17_22705	COG1744	ABC transporter substrate-binding protein PnrA-like
KHC17_22710	COG3845	ABC transporter
KHC17_22715	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHC17_22720	COG1079	Belongs to the binding-protein-dependent transport system permease family
KHC17_22725	COG0295	cytidine deaminase activity
KHC17_22730	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KHC17_22735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHC17_22740	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KHC17_22750	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHC17_22755	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KHC17_22760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KHC17_22770	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KHC17_22775	COG1845	cytochrome c oxidase, subunit III
KHC17_22780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KHC17_22785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KHC17_22790	COG0477	Major facilitator Superfamily
KHC17_22795	COG0067	glutamate synthase
KHC17_22795	COG0069	glutamate synthase activity
KHC17_22795	COG0070	glutamate synthase
KHC17_22800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KHC17_22815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KHC17_22825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KHC17_22855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_22875	COG0848	biopolymer transport protein
KHC17_22885	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
KHC17_22900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KHC17_22905	COG3454	Phosphonate metabolism
KHC17_22910	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
KHC17_22920	COG3639	organic phosphonate transmembrane transporter activity
KHC17_22925	COG3639	organic phosphonate transmembrane transporter activity
KHC17_22935	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHC17_22945	COG4778	phosphonate C-P lyase system protein PhnL
KHC17_22950	COG4107	phosphonate C-P lyase system protein PhnK
KHC17_22955	COG3627	carbon phosphorus lyase activity
KHC17_22960	COG3626	phosphonate metabolism
KHC17_22965	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
KHC17_22970	COG3624	Phosphonate C-P lyase system protein PhnG
KHC17_22975	COG2188	Transcriptional regulator
KHC17_22980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KHC17_22985	COG0837	glucose binding
KHC17_22990	COG1803	Methylglyoxal synthase
KHC17_22995	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
KHC17_23000	COG4166	transmembrane transport
KHC17_23005	COG4174	ABC transporter (Permease)
KHC17_23010	COG4239	(ABC) transporter, permease
KHC17_23015	COG4172	Belongs to the ABC transporter superfamily
KHC17_23020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_23025	COG0174	glutamine synthetase
KHC17_23030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KHC17_23035	COG3265	gluconokinase activity
KHC17_23040	COG1174	glycine betaine transport
KHC17_23045	COG1125	glycine betaine transport
KHC17_23050	COG1174	glycine betaine transport
KHC17_23055	COG1732	Glycine betaine
KHC17_23065	COG1959	2 iron, 2 sulfur cluster binding
KHC17_23070	COG1840	ABC-type Fe3 transport system, periplasmic component
KHC17_23085	COG0697	spore germination
KHC17_23105	COG0791	NLP P60 protein
KHC17_23115	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHC17_23120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KHC17_23155	COG4964	Belongs to the GSP D family
KHC17_23200	COG3422	double-strand break repair
KHC17_23205	COG3757	hydrolase, family 25
KHC17_23210	COG0697	spore germination
KHC17_23215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHC17_23245	COG0481	GTPase activity
KHC17_23250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHC17_23265	COG1396	sequence-specific DNA binding
KHC17_23280	COG1917	Cupin 2, conserved barrel domain protein
KHC17_23280	COG2169	Transcriptional regulator
KHC17_23285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KHC17_23310	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHC17_23315	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KHC17_23320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHC17_23330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHC17_23335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHC17_23335	COG0072	phenylalanine-tRNA ligase activity
KHC17_23340	COG0667	Aldo Keto reductase
KHC17_23360	COG4977	sequence-specific DNA binding
KHC17_23385	COG1570	exodeoxyribonuclease VII activity
KHC17_23390	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_23400	COG1846	Transcriptional regulator
KHC17_23405	COG0697	spore germination
KHC17_23410	COG2309	aminopeptidase activity
KHC17_23415	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHC17_23420	COG1393	Belongs to the ArsC family
KHC17_23455	COG1902	pentaerythritol trinitrate reductase activity
KHC17_23470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KHC17_23470	COG0519	Catalyzes the synthesis of GMP from XMP
KHC17_23485	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
KHC17_23515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHC17_23525	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KHC17_23535	COG1968	undecaprenyl-diphosphatase activity
KHC17_23550	COG0284	orotidine-5'-phosphate decarboxylase activity
KHC17_23560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KHC17_23570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHC17_23575	COG0792	nuclease activity
KHC17_23590	COG1175	transmembrane transport
KHC17_23600	COG3842	ATPase activity
KHC17_23610	COG0189	ligase activity
KHC17_23615	COG0606	chelatase, subunit chli
KHC17_23625	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KHC17_23630	COG1280	lysine exporter protein (LysE YggA)
KHC17_23635	COG0756	dUTP diphosphatase activity
KHC17_23640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHC17_23645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHC17_23660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KHC17_23665	COG2226	methyltransferase
KHC17_23670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KHC17_23675	COG1024	Enoyl-CoA hydratase
KHC17_23680	COG0268	Binds directly to 16S ribosomal RNA
KHC17_23730	COG1115	amino acid carrier protein
KHC17_23750	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KHC17_23820	COG1396	sequence-specific DNA binding
KHC17_23850	COG0385	Bile acid
KHC17_23855	COG0667	Aldo Keto reductase
KHC17_23860	COG0583	DNA-binding transcription factor activity
KHC17_23870	COG0179	Fumarylacetoacetate (FAA) hydrolase
KHC17_23880	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_23890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_23905	COG1132	(ABC) transporter
KHC17_23925	COG2801	Transposase and inactivated derivatives
KHC17_23965	COG0277	FAD linked oxidase domain protein
KHC17_23970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KHC17_23970	COG0546	phosphoglycolate phosphatase activity
KHC17_23975	COG1216	Glycosyl transferase, family 2
KHC17_23975	COG0438	transferase activity, transferring glycosyl groups
KHC17_23980	COG1216	Glycosyl transferase, family 2
KHC17_23980	COG0438	transferase activity, transferring glycosyl groups
KHC17_23985	COG3754	Rhamnan synthesis protein F
KHC17_23995	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHC17_24000	COG1091	dTDP-4-dehydrorhamnose reductase activity
KHC17_24005	COG1088	dTDP-glucose 4,6-dehydratase activity
KHC17_24010	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KHC17_24015	COG4310	Domain of unknown function (DUF2172)
KHC17_24030	COG1086	Polysaccharide biosynthesis protein
KHC17_24035	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KHC17_24040	COG1083	cytidylyl-transferase
KHC17_24050	COG2089	acid synthase
KHC17_24080	COG3547	Transposase (IS116 IS110 IS902 family)
KHC17_24090	COG0210	DNA helicase
KHC17_24100	COG1233	COG1233 Phytoene dehydrogenase and related
KHC17_24115	COG0395	ABC-type sugar transport system, permease component
KHC17_24120	COG3842	ATPase activity
KHC17_24130	COG0444	Belongs to the ABC transporter superfamily
KHC17_24190	COG0667	Aldo Keto reductase
KHC17_24200	COG1309	transcriptional regulator
KHC17_24215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_24230	COG3181	Tripartite tricarboxylate transporter family receptor
KHC17_24240	COG2186	Transcriptional regulator
KHC17_24245	COG3181	Tripartite tricarboxylate transporter family receptor
KHC17_24255	COG0583	DNA-binding transcription factor activity
KHC17_24270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_24275	COG0745	RESPONSE REGULATOR receiver
KHC17_24280	COG2205	protein histidine kinase activity
KHC17_24355	COG3701	Conjugal transfer protein
KHC17_24360	COG3846	protein secretion by the type IV secretion system
KHC17_24370	COG5314	conjugation
KHC17_24375	COG3451	type IV secretory pathway VirB4
KHC17_24390	COG4962	Type ii secretion system protein e
KHC17_24400	COG1192	Involved in chromosome partitioning
KHC17_24405	COG1475	DNA binding
KHC17_24410	COG0640	Transcriptional regulator
KHC17_24555	COG1793	dna ligase
KHC17_24555	COG3285	dna ligase
KHC17_24560	COG0071	Belongs to the small heat shock protein (HSP20) family
KHC17_24605	COG0587	DNA-directed DNA polymerase activity
KHC17_24645	COG1475	DNA binding
KHC17_24670	COG5489	Protein of unknown function (DUF736)
KHC17_24690	COG3831	ATPase activity
KHC17_24715	COG1879	ABC-type sugar transport system periplasmic component
KHC17_24720	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_24765	COG0587	DNA-directed DNA polymerase activity
KHC17_24810	COG1475	DNA binding
KHC17_24835	COG5489	Protein of unknown function (DUF736)
KHC17_24910	COG4774	siderophore transport
KHC17_24935	COG2204	response regulator
KHC17_24955	COG2358	TRAP transporter, solute receptor (TAXI family
KHC17_24970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KHC17_25000	COG1522	sequence-specific DNA binding
KHC17_25035	COG1177	transmembrane transport
KHC17_25040	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHC17_25045	COG3842	ATPase activity
KHC17_25075	COG1802	Transcriptional regulator
KHC17_25080	COG3842	ATPase activity
KHC17_25085	COG4209	transmembrane transport
KHC17_25090	COG0395	ABC-type sugar transport system, permease component
KHC17_25095	COG1653	transport
KHC17_25105	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_25115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KHC17_25125	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_25130	COG2211	Major facilitator Superfamily
KHC17_25150	COG3701	Conjugal transfer protein
KHC17_25155	COG3846	protein secretion by the type IV secretion system
KHC17_25165	COG5314	conjugation
KHC17_25170	COG3451	type IV secretory pathway VirB4
KHC17_25185	COG4962	Type ii secretion system protein e
KHC17_25195	COG1192	Involved in chromosome partitioning
KHC17_25200	COG1475	DNA binding
KHC17_25205	COG0640	Transcriptional regulator
KHC17_25210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHC17_25240	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KHC17_25265	COG3436	PFAM IS66 Orf2 family protein
KHC17_25300	COG2192	nodulation
KHC17_25355	COG0697	spore germination
KHC17_25375	COG0640	Transcriptional regulator
KHC17_25390	COG1309	transcriptional regulator
KHC17_25400	COG2207	Transcriptional regulator
KHC17_25405	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_25450	COG0753	catalase activity
KHC17_25455	COG3685	Protein conserved in bacteria
KHC17_25520	COG1573	uracil-dna glycosylase
KHC17_25550	COG0517	IMP dehydrogenase activity
KHC17_25605	COG0402	S-adenosylhomocysteine deaminase activity
KHC17_25610	COG0583	DNA-binding transcription factor activity
KHC17_25630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_25665	COG4974	Belongs to the 'phage' integrase family
KHC17_25670	COG4974	Belongs to the 'phage' integrase family
KHC17_25675	COG4974	Belongs to the 'phage' integrase family
KHC17_25685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KHC17_25695	COG4227	nucleotidyltransferase activity
KHC17_25700	COG3550	peptidyl-serine autophosphorylation
KHC17_25710	COG0475	glutathione-regulated potassium exporter activity
KHC17_25710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHC17_25735	COG1879	ABC-type sugar transport system periplasmic component
KHC17_25750	COG1172	Belongs to the binding-protein-dependent transport system permease family
KHC17_25770	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_25780	COG4467	Involved in initiation control of chromosome replication
KHC17_25820	COG0270	DNA (cytosine-5-)-methyltransferase activity
KHC17_25825	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHC17_25860	COG1484	DNA-dependent DNA replication
KHC17_25865	COG2390	Transcriptional regulator
KHC17_25865	COG4584	PFAM Integrase catalytic
KHC17_25870	COG1002	Type II restriction enzyme, methylase subunits
KHC17_25890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KHC17_25925	COG2814	Major facilitator Superfamily
KHC17_25945	COG0583	DNA-binding transcription factor activity
KHC17_25950	COG0604	alcohol dehydrogenase
KHC17_25975	COG4529	Protein conserved in bacteria
KHC17_26105	COG1309	transcriptional regulator
KHC17_26175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHC17_26180	COG0436	Aminotransferase
KHC17_26195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_26200	COG0765	amino acid transport
KHC17_26210	COG1126	abc transporter atp-binding protein
KHC17_26220	COG2186	Transcriptional regulator
KHC17_26235	COG0714	Associated with various cellular activities
KHC17_26275	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KHC17_26325	COG4459	periplasmic nitrate reductase
KHC17_26350	COG3005	denitrification pathway
KHC17_26365	COG2188	Transcriptional regulator
KHC17_26375	COG0673	inositol 2-dehydrogenase activity
KHC17_26390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KHC17_26400	COG1129	ABC transporter
KHC17_26415	COG2390	Transcriptional regulator
KHC17_26420	COG3684	Belongs to the aldolase LacD family
KHC17_26430	COG1012	belongs to the aldehyde dehydrogenase family
KHC17_26455	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_26460	COG3433	isochorismatase activity
KHC17_26460	COG1535	isochorismatase
KHC17_26465	COG1021	2,3-dihydroxybenzoate-AMP ligase
KHC17_26470	COG1169	isochorismate synthase
KHC17_26520	COG1278	Cold shock
KHC17_26570	COG5489	Protein of unknown function (DUF736)
KHC17_26575	COG0776	regulation of translation
KHC17_26580	COG3831	ATPase activity
KHC17_26585	COG3505	Type IV secretory pathway VirD4
KHC17_26620	COG1454	alcohol dehydrogenase
KHC17_26625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KHC17_26635	COG4172	Belongs to the ABC transporter superfamily
KHC17_26640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_26645	COG0601	transmembrane transport
KHC17_26650	COG4166	transmembrane transport
KHC17_26670	COG4372	Transposase
KHC17_26685	COG0459	protein refolding
KHC17_26690	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHC17_26695	COG5425	PFAM Usg family protein
KHC17_26705	COG0071	Belongs to the small heat shock protein (HSP20) family
KHC17_26715	COG0625	glutathione transferase activity
KHC17_26740	COG0583	DNA-binding transcription factor activity
KHC17_26820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_26835	COG0277	FAD linked oxidase domain protein
KHC17_26840	COG3550	peptidyl-serine autophosphorylation
KHC17_26845	COG3620	sequence-specific DNA binding
KHC17_26870	COG3177	Filamentation induced by cAMP protein fic
KHC17_26885	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_26930	COG0596	Alpha beta hydrolase
KHC17_26950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KHC17_26955	COG1063	alcohol dehydrogenase
KHC17_27015	COG2207	Transcriptional regulator
KHC17_27025	COG1192	Involved in chromosome partitioning
KHC17_27030	COG1475	DNA binding
KHC17_27035	COG0640	Transcriptional regulator
KHC17_27045	COG0577	efflux transmembrane transporter activity
KHC17_27060	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KHC17_27075	COG1653	transport
KHC17_27080	COG1175	transmembrane transport
KHC17_27085	COG0395	ABC-type sugar transport system, permease component
KHC17_27090	COG1063	alcohol dehydrogenase
KHC17_27095	COG3842	ATPase activity
KHC17_27100	COG3920	Histidine kinase
KHC17_27100	COG2202	Pas domain
KHC17_27105	COG0784	Response regulator, receiver
KHC17_27110	COG0784	Response regulator, receiver
KHC17_27110	COG4191	Histidine kinase
KHC17_27130	COG1487	ribonuclease activity
KHC17_27170	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHC17_27180	COG4467	Involved in initiation control of chromosome replication
KHC17_27190	COG4467	Involved in initiation control of chromosome replication
KHC17_27220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KHC17_27295	COG1309	transcriptional regulator
KHC17_27320	COG4221	oxidoreductase activity
KHC17_27330	COG4221	oxidoreductase activity
KHC17_27360	COG2814	Major facilitator Superfamily
KHC17_27365	COG0583	DNA-binding transcription factor activity
KHC17_27385	COG0589	response to stress
KHC17_27395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KHC17_27395	COG4651	solute:proton antiporter activity
KHC17_27440	COG2271	Major facilitator Superfamily
KHC17_27445	COG1309	transcriptional regulator
KHC17_27450	COG1280	lysine exporter protein (LysE YggA)
KHC17_27520	COG3547	Transposase (IS116 IS110 IS902 family)
KHC17_27525	COG4584	PFAM Integrase catalytic
KHC17_27525	COG2390	Transcriptional regulator
KHC17_27530	COG1484	DNA-dependent DNA replication
KHC17_27535	COG4372	Transposase
KHC17_27540	COG3436	PFAM IS66 Orf2 family protein
KHC17_27545	COG2963	transposase activity
KHC17_27555	COG1228	amidohydrolase
KHC17_27575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KHC17_27580	COG4644	lycopene metabolic process
KHC17_27610	COG0464	growth
KHC17_27615	COG0747	negative chemotaxis
KHC17_27620	COG0601	transmembrane transport
KHC17_27625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_27630	COG0444	Belongs to the ABC transporter superfamily
KHC17_27635	COG4608	Belongs to the ABC transporter superfamily
KHC17_27655	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KHC17_27660	COG3077	Addiction module antitoxin, RelB DinJ family
KHC17_27675	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_27685	COG3268	Saccharopine dehydrogenase
KHC17_27700	COG3321	synthase
KHC17_27700	COG0604	alcohol dehydrogenase
KHC17_27700	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_27710	COG0583	DNA-binding transcription factor activity
KHC17_27715	COG0583	DNA-binding transcription factor activity
KHC17_27730	COG1846	Transcriptional regulator
KHC17_27755	COG4598	ABC transporter
KHC17_27760	COG0765	amino acid transport
KHC17_27765	COG0765	amino acid transport
KHC17_27775	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHC17_27780	COG1802	Transcriptional regulator
KHC17_27825	COG3177	Filamentation induced by cAMP protein fic
KHC17_27840	COG0534	Mate efflux family protein
KHC17_27860	COG2072	flavoprotein involved in K transport
KHC17_27865	COG3842	ATPase activity
KHC17_27870	COG1177	transmembrane transport
KHC17_27875	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHC17_27885	COG0583	DNA-binding transcription factor activity
KHC17_27905	COG0601	transmembrane transport
KHC17_27910	COG0444	Belongs to the ABC transporter superfamily
KHC17_27915	COG4608	Belongs to the ABC transporter superfamily
KHC17_27920	COG2188	Transcriptional regulator
KHC17_27925	COG1363	Peptidase, m42
KHC17_27935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KHC17_27940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KHC17_27950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_27960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KHC17_27970	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KHC17_27970	COG1082	Xylose isomerase domain protein TIM barrel
KHC17_27975	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KHC17_27980	COG1309	transcriptional regulator
KHC17_27985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHC17_28010	COG0587	DNA-directed DNA polymerase activity
KHC17_28050	COG1278	Cold shock
KHC17_28105	COG5489	Protein of unknown function (DUF736)
KHC17_28110	COG0776	regulation of translation
KHC17_28115	COG3831	ATPase activity
KHC17_28120	COG3505	Type IV secretory pathway VirD4
KHC17_28140	COG0583	DNA-binding transcription factor activity
KHC17_28160	COG0529	Catalyzes the synthesis of activated sulfate
KHC17_28175	COG2197	response regulator
KHC17_28190	COG0745	RESPONSE REGULATOR receiver
KHC17_28230	COG3842	ATPase activity
KHC17_28235	COG4208	sulfate ABC transporter
KHC17_28240	COG1176	ABC-type spermidine putrescine transport system, permease component I
KHC17_28255	COG0243	molybdopterin cofactor binding
KHC17_28260	COG4172	Belongs to the ABC transporter superfamily
KHC17_28265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHC17_28270	COG0601	transmembrane transport
KHC17_28275	COG4166	transmembrane transport
KHC17_28280	COG3550	peptidyl-serine autophosphorylation
KHC17_28295	COG0459	protein refolding
KHC17_28300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHC17_28305	COG5425	PFAM Usg family protein
KHC17_28315	COG0071	Belongs to the small heat shock protein (HSP20) family
KHC17_28325	COG0625	glutathione transferase activity
KHC17_28350	COG0583	DNA-binding transcription factor activity
KHC17_28365	COG3838	Conjugal transfer protein Trbc
KHC17_28370	COG3702	type iv secretory pathway
KHC17_28375	COG3451	type IV secretory pathway VirB4
KHC17_28390	COG3704	protein secretion by the type IV secretion system
KHC17_28400	COG3736	Type IV secretory pathway, component VirB8
KHC17_28405	COG3504	Conjugal transfer protein
KHC17_28410	COG2948	multi-organism process
KHC17_28415	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
KHC17_28430	COG0583	DNA-binding transcription factor activity
KHC17_28440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KHC17_28500	COG0446	pyridine nucleotide-disulphide oxidoreductase
KHC17_28510	COG3547	Transposase (IS116 IS110 IS902 family)
KHC17_28520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KHC17_28525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHC17_28535	COG0574	Belongs to the PEP-utilizing enzyme family
KHC17_28535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHC17_28550	COG2963	transposase activity
KHC17_28565	COG2963	transposase activity
KHC17_28615	COG1063	alcohol dehydrogenase
KHC17_28620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KHC17_28625	COG0459	protein refolding
KHC17_28635	COG0071	Belongs to the small heat shock protein (HSP20) family
KHC17_28655	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KHC17_28660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHC17_28675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KHC17_28680	COG4191	Histidine kinase
KHC17_28680	COG0784	Response regulator, receiver
KHC17_28690	COG2801	Transposase and inactivated derivatives
KHC17_28710	COG0596	Alpha beta hydrolase
KHC17_28720	COG3842	ATPase activity
KHC17_28725	COG4209	transmembrane transport
KHC17_28730	COG0395	ABC-type sugar transport system, permease component
KHC17_28735	COG1653	transport
KHC17_28745	COG1028	Short-chain dehydrogenase reductase Sdr
KHC17_28755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHC17_28765	COG4948	Mandelate Racemase Muconate Lactonizing
KHC17_28780	COG0531	amino acid
KHC17_28800	COG3668	Plasmid stabilization system
KHC17_28805	COG3609	addiction module antidote protein, CC2985 family
KHC17_28815	COG0165	Argininosuccinate lyase
KHC17_28825	COG1126	abc transporter atp-binding protein
KHC17_28830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KHC17_28835	COG2079	MmgE PrpD family protein
KHC17_28855	COG3550	peptidyl-serine autophosphorylation
KHC17_28860	COG3620	sequence-specific DNA binding
KHC17_28890	COG2226	methyltransferase
KHC17_28920	COG2207	Transcriptional regulator
KHC17_28935	COG1192	Involved in chromosome partitioning
KHC17_28940	COG1475	DNA binding
KHC17_28945	COG0640	Transcriptional regulator
KHC17_28970	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KHC17_29040	COG0739	heme binding
KHC17_29040	COG0741	lytic transglycosylase activity
KHC17_29040	COG1196	nuclear chromosome segregation
KHC17_29090	COG2963	transposase activity
KHC17_29100	COG1136	(ABC) transporter
KHC17_29130	COG2076	Multidrug Resistance protein
KHC17_29140	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KHC17_29155	COG2205	protein histidine kinase activity
KHC17_29165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_29170	COG1136	(ABC) transporter
KHC17_29170	COG0577	efflux transmembrane transporter activity
KHC17_29175	COG0454	-acetyltransferase
KHC17_29190	COG5002	protein histidine kinase activity
KHC17_29195	COG0745	RESPONSE REGULATOR receiver
KHC17_29200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHC17_29210	COG1473	amidohydrolase
KHC17_29220	COG0765	amino acid transport
KHC17_29280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KHC17_29290	COG1024	Enoyl-CoA hydratase