locus-tag	class	description
A6U84_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
A6U84_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6U84_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A6U84_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A6U84_00025	COG1420	regulation of RNA biosynthetic process
A6U84_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A6U84_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6U84_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
A6U84_00050	COG1137	ATPase activity
A6U84_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A6U84_00065	COG0616	signal peptide processing
A6U84_00070	COG0776	regulation of translation
A6U84_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6U84_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
A6U84_00095	COG0784	Response regulator, receiver
A6U84_00095	COG2205	protein histidine kinase activity
A6U84_00095	COG5002	protein histidine kinase activity
A6U84_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
A6U84_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
A6U84_00115	COG0728	peptidoglycan biosynthetic process
A6U84_00125	COG0180	Tryptophanyl-tRNA synthetase
A6U84_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
A6U84_00140	COG1214	PFAM Peptidase M22, glycoprotease
A6U84_00145	COG0456	acetyltransferase
A6U84_00145	COG1214	PFAM Peptidase M22, glycoprotease
A6U84_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A6U84_00165	COG1702	phosphate starvation-inducible protein PhoH
A6U84_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
A6U84_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
A6U84_00185	COG1396	sequence-specific DNA binding
A6U84_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
A6U84_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A6U84_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_00210	COG0242	peptide deformylase activity
A6U84_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
A6U84_00220	COG0101	tRNA pseudouridine synthase activity
A6U84_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6U84_00235	COG2171	N-acyltransferase activity
A6U84_00245	COG0840	transmembrane signaling receptor activity
A6U84_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
A6U84_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
A6U84_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A6U84_00295	COG0706	membrane insertase activity
A6U84_00300	COG0594	ribonuclease P activity
A6U84_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
A6U84_00310	COG0840	transmembrane signaling receptor activity
A6U84_00325	COG2226	methyltransferase
A6U84_00330	COG3842	ATPase activity
A6U84_00335	COG1175	transmembrane transport
A6U84_00340	COG0395	ABC-type sugar transport system, permease component
A6U84_00355	COG0427	acetyl-CoA hydrolase
A6U84_00365	COG3938	Belongs to the proline racemase family
A6U84_00370	COG0418	dihydroorotase activity
A6U84_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A6U84_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A6U84_00400	COG0166	Belongs to the GPI family
A6U84_00405	COG0318	PFAM AMP-dependent synthetase and ligase
A6U84_00410	COG3842	ATPase activity
A6U84_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
A6U84_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A6U84_00425	COG4774	siderophore transport
A6U84_00465	COG2326	polyphosphate kinase activity
A6U84_00470	COG5002	protein histidine kinase activity
A6U84_00475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A6U84_00480	COG0573	inorganic phosphate transmembrane transporter activity
A6U84_00490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A6U84_00495	COG0704	Plays a role in the regulation of phosphate uptake
A6U84_00500	COG0745	RESPONSE REGULATOR receiver
A6U84_00510	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A6U84_00515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A6U84_00525	COG2967	ApaG domain
A6U84_00535	COG0717	Belongs to the dCTP deaminase family
A6U84_00545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A6U84_00595	COG0167	dihydroorotate dehydrogenase activity
A6U84_00610	COG2264	protein methyltransferase activity
A6U84_00630	COG1959	2 iron, 2 sulfur cluster binding
A6U84_00635	COG1201	RNA secondary structure unwinding
A6U84_00665	COG1960	acyl-CoA dehydrogenase activity
A6U84_00670	COG0183	Belongs to the thiolase family
A6U84_00675	COG1024	Enoyl-CoA hydratase
A6U84_00675	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6U84_00690	COG1320	monovalent cation:proton antiporter activity
A6U84_00695	COG2212	antiporter activity
A6U84_00700	COG1863	multisubunit Na H antiporter MnhE subunit
A6U84_00705	COG0651	ATP synthesis coupled electron transport
A6U84_00710	COG1006	Multisubunit Na H antiporter MnhC subunit
A6U84_00715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A6U84_00715	COG2111	Na H antiporter
A6U84_00725	COG0840	transmembrane signaling receptor activity
A6U84_00735	COG0745	RESPONSE REGULATOR receiver
A6U84_00740	COG2198	Histidine kinase
A6U84_00740	COG0643	Histidine kinase
A6U84_00745	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A6U84_00750	COG2201	protein-glutamate methylesterase activity
A6U84_00755	COG0745	RESPONSE REGULATOR receiver
A6U84_00760	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A6U84_00770	COG1766	The M ring may be actively involved in energy transduction
A6U84_00775	COG2771	luxR family
A6U84_00785	COG2972	Histidine kinase
A6U84_00785	COG0840	transmembrane signaling receptor activity
A6U84_00790	COG0784	Response regulator, receiver
A6U84_00790	COG2198	Histidine kinase
A6U84_00790	COG2205	protein histidine kinase activity
A6U84_00795	COG1970	mechanosensitive ion channel activity
A6U84_00800	COG0436	Aminotransferase
A6U84_00815	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A6U84_00820	COG0424	maF-like protein
A6U84_00825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
A6U84_00835	COG5328	Belongs to the UPF0262 family
A6U84_00840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A6U84_00850	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A6U84_00865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
A6U84_00880	COG1338	Plays a role in the flagellum-specific transport system
A6U84_00890	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
A6U84_00900	COG1706	bacterial-type flagellum-dependent cell motility
A6U84_00905	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
A6U84_00910	COG4786	Flagellar basal body rod
A6U84_00915	COG1677	Flagellar hook-basal body complex protein FliE
A6U84_00920	COG1558	bacterial-type flagellum-dependent cell motility
A6U84_00925	COG1815	bacterial-type flagellum-dependent cell motility
A6U84_00935	COG1157	protein secretion by the type III secretion system
A6U84_00940	COG4786	Flagellar basal body rod
A6U84_00950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
A6U84_00955	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6U84_00960	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6U84_00965	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
A6U84_00970	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6U84_00990	COG1360	Flagellar Motor Protein
A6U84_01015	COG1749	Flagellar hook protein flgE
A6U84_01035	COG5443	negative regulation of bacterial-type flagellum assembly
A6U84_01040	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
A6U84_01050	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
A6U84_01090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
A6U84_01095	COG1609	Transcriptional regulator
A6U84_01100	COG1653	transport
A6U84_01105	COG1175	transmembrane transport
A6U84_01110	COG0395	ABC-type sugar transport system, permease component
A6U84_01115	COG0366	Alpha amylase catalytic
A6U84_01120	COG3842	ATPase activity
A6U84_01135	COG0129	dihydroxy-acid dehydratase activity
A6U84_01140	COG0363	glucosamine-6-phosphate deaminase activity
A6U84_01145	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
A6U84_01155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_01165	COG2081	HI0933 family
A6U84_01185	COG2224	Isocitrate lyase
A6U84_01200	COG3842	ATPase activity
A6U84_01205	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_01210	COG1177	transmembrane transport
A6U84_01220	COG2205	protein histidine kinase activity
A6U84_01230	COG0248	Ppx GppA phosphatase
A6U84_01235	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
A6U84_01240	COG0477	Major facilitator Superfamily
A6U84_01270	COG0521	Mo-molybdopterin cofactor biosynthetic process
A6U84_01275	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
A6U84_01285	COG0142	geranyltranstransferase activity
A6U84_01310	COG0752	glycyl-tRNA synthetase alpha subunit
A6U84_01315	COG1704	LemA family
A6U84_01320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A6U84_01330	COG0751	glycine-tRNA ligase activity
A6U84_01345	COG1683	Conserved Protein
A6U84_01350	COG0840	transmembrane signaling receptor activity
A6U84_01360	COG0151	Belongs to the GarS family
A6U84_01365	COG2183	response to ionizing radiation
A6U84_01370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A6U84_01395	COG0583	DNA-binding transcription factor activity
A6U84_01415	COG0306	phosphate transporter
A6U84_01425	COG0561	phosphatase activity
A6U84_01430	COG0438	transferase activity, transferring glycosyl groups
A6U84_01435	COG2186	Transcriptional regulator
A6U84_01445	COG0583	DNA-binding transcription factor activity
A6U84_01450	COG0277	FAD linked oxidase domain protein
A6U84_01455	COG0277	FAD linked oxidase domain protein
A6U84_01460	COG0247	lactate metabolic process
A6U84_01470	COG1376	ErfK ybiS ycfS ynhG family protein
A6U84_01485	COG2855	membrane
A6U84_01490	COG0583	DNA-binding transcription factor activity
A6U84_01510	COG0124	histidyl-tRNA synthetase
A6U84_01520	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
A6U84_01525	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A6U84_01530	COG2259	Doxx family
A6U84_01540	COG0459	protein refolding
A6U84_01545	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
A6U84_01555	COG0196	riboflavin kinase activity
A6U84_01560	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A6U84_01570	COG0590	tRNA wobble adenosine to inosine editing
A6U84_01575	COG1187	pseudouridine synthase activity
A6U84_01580	COG0742	ribosomal rna small subunit methyltransferase
A6U84_01585	COG1752	Esterase of the alpha-beta hydrolase superfamily
A6U84_01595	COG0312	modulator of DNA gyrase
A6U84_01610	COG1519	Transferase
A6U84_01620	COG1663	tetraacyldisaccharide 4'-kinase activity
A6U84_01635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A6U84_01640	COG2205	protein histidine kinase activity
A6U84_01640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_01645	COG5001	Diguanylate cyclase
A6U84_01645	COG3300	MHYT domain
A6U84_01650	COG3386	PFAM SMP-30 Gluconolaconase
A6U84_01655	COG0800	Aldolase
A6U84_01660	COG3734	2-keto-3-deoxy-galactonokinase
A6U84_01665	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_01675	COG2197	response regulator
A6U84_01690	COG0598	Magnesium transport protein CorA
A6U84_01695	COG3158	transport of potassium into the cell
A6U84_01710	COG0356	it plays a direct role in the translocation of protons across the membrane
A6U84_01720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A6U84_01725	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
A6U84_01735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A6U84_01755	COG0009	L-threonylcarbamoyladenylate synthase
A6U84_01765	COG4638	Rieske (2fe-2S)
A6U84_01790	COG1960	acyl-CoA dehydrogenase activity
A6U84_01805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A6U84_01810	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A6U84_01815	COG0840	transmembrane signaling receptor activity
A6U84_01840	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
A6U84_01845	COG1741	Belongs to the pirin family
A6U84_01850	COG1722	exodeoxyribonuclease VII activity
A6U84_01855	COG0123	including yeast histone deacetylase and acetoin utilization protein
A6U84_01860	COG1268	BioY protein
A6U84_01865	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A6U84_01870	COG1122	ATPase activity
A6U84_01875	COG3214	Protein conserved in bacteria
A6U84_01880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6U84_01880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6U84_01885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
A6U84_01905	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A6U84_01910	COG0484	heat shock protein binding
A6U84_01920	COG0259	pyridoxamine-phosphate oxidase activity
A6U84_01935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6U84_01945	COG0312	modulator of DNA gyrase
A6U84_01970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A6U84_01975	COG0109	protoheme IX farnesyltransferase activity
A6U84_01985	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
A6U84_02000	COG3346	SURF1 family
A6U84_02005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
A6U84_02010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A6U84_02015	COG0328	RNA-DNA hybrid ribonuclease activity
A6U84_02025	COG0678	peroxiredoxin activity
A6U84_02025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A6U84_02035	COG1678	Uncharacterized ACR, COG1678
A6U84_02055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A6U84_02060	COG0612	Peptidase, M16
A6U84_02075	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6U84_02095	COG2189	Belongs to the N(4) N(6)-methyltransferase family
A6U84_02115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A6U84_02120	COG1196	nuclear chromosome segregation
A6U84_02125	COG2514	catechol 2,3-dioxygenase activity
A6U84_02130	COG0574	Belongs to the PEP-utilizing enzyme family
A6U84_02130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A6U84_02145	COG1823	symporter activity
A6U84_02165	COG0579	oxidoreductase
A6U84_02195	COG2895	sulfate adenylyltransferase (ATP) activity
A6U84_02200	COG0175	sulfate reduction
A6U84_02205	COG0175	sulfate reduction
A6U84_02210	COG1959	2 iron, 2 sulfur cluster binding
A6U84_02215	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A6U84_02220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A6U84_02225	COG4208	sulfate ABC transporter
A6U84_02230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A6U84_02240	COG2199	diguanylate cyclase activity
A6U84_02240	COG2203	Gaf domain
A6U84_02240	COG2200	EAL domain
A6U84_02250	COG1309	transcriptional regulator
A6U84_02255	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_02260	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
A6U84_02305	COG0477	Major facilitator Superfamily
A6U84_02315	COG1793	dna ligase
A6U84_02315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A6U84_02330	COG1376	ErfK ybiS ycfS ynhG family protein
A6U84_02335	COG1376	ErfK ybiS ycfS ynhG family protein
A6U84_02355	COG1846	Transcriptional regulator
A6U84_02360	COG1764	response to oxidative stress
A6U84_02375	COG0488	(ABC) transporter
A6U84_02410	COG0583	DNA-binding transcription factor activity
A6U84_02415	COG4221	oxidoreductase activity
A6U84_02425	COG0433	COG0433 Predicted ATPase
A6U84_02435	COG1733	regulation of RNA biosynthetic process
A6U84_02440	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
A6U84_02450	COG1280	lysine exporter protein (LysE YggA)
A6U84_02455	COG0656	L-ascorbic acid biosynthetic process
A6U84_02460	COG2378	regulation of single-species biofilm formation
A6U84_02470	COG4106	trans-aconitate 2-methyltransferase activity
A6U84_02475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6U84_02480	COG0840	transmembrane signaling receptor activity
A6U84_02485	COG0583	DNA-binding transcription factor activity
A6U84_02500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A6U84_02520	COG3909	cytochrome
A6U84_02525	COG2010	Cytochrome c
A6U84_02555	COG0789	Transcriptional regulator
A6U84_02585	COG4176	ABC-type proline glycine betaine transport system permease component
A6U84_02605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_02615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6U84_02615	COG2169	Transcriptional regulator
A6U84_02625	COG2514	catechol 2,3-dioxygenase activity
A6U84_02645	COG1272	protein, Hemolysin III
A6U84_02655	COG1280	lysine exporter protein (LysE YggA)
A6U84_02660	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6U84_02665	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A6U84_02665	COG2111	Na H antiporter
A6U84_02670	COG2111	Na H antiporter
A6U84_02675	COG1006	Multisubunit Na H antiporter MnhC subunit
A6U84_02680	COG0651	ATP synthesis coupled electron transport
A6U84_02685	COG1863	multisubunit Na H antiporter MnhE subunit
A6U84_02690	COG2212	antiporter activity
A6U84_02695	COG1320	monovalent cation:proton antiporter activity
A6U84_02700	COG4957	zinc ion binding
A6U84_02715	COG2166	iron-sulfur cluster assembly
A6U84_02725	COG2205	protein histidine kinase activity
A6U84_02780	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A6U84_02785	COG2983	Belongs to the UPF0260 family
A6U84_02820	COG1621	beta-fructofuranosidase activity
A6U84_02825	COG2202	Pas domain
A6U84_02825	COG3920	Histidine kinase
A6U84_02830	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A6U84_02880	COG4695	Portal protein
A6U84_02985	COG4235	cytochrome complex assembly
A6U84_02990	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
A6U84_02995	COG1138	Cytochrome C-type biogenesis protein
A6U84_03000	COG3088	subunit of a heme lyase
A6U84_03005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6U84_03010	COG0745	RESPONSE REGULATOR receiver
A6U84_03020	COG3011	Protein conserved in bacteria
A6U84_03030	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A6U84_03035	COG2202	Pas domain
A6U84_03035	COG2205	protein histidine kinase activity
A6U84_03045	COG0308	aminopeptidase N
A6U84_03065	COG0443	Heat shock 70 kDa protein
A6U84_03075	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_03085	COG1733	regulation of RNA biosynthetic process
A6U84_03105	COG0604	alcohol dehydrogenase
A6U84_03110	COG1733	regulation of RNA biosynthetic process
A6U84_03115	COG1968	undecaprenyl-diphosphatase activity
A6U84_03120	COG2239	Acts as a magnesium transporter
A6U84_03125	COG2814	Major facilitator Superfamily
A6U84_03155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A6U84_03360	COG0741	lytic transglycosylase activity
A6U84_03365	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_03370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
A6U84_03375	COG0840	transmembrane signaling receptor activity
A6U84_03385	COG1758	RNA polymerase activity
A6U84_03405	COG0736	holo-[acyl-carrier-protein] synthase activity
A6U84_03410	COG0681	Belongs to the peptidase S26 family
A6U84_03415	COG0571	ribonuclease III activity
A6U84_03420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A6U84_03425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6U84_03430	COG0784	Response regulator, receiver
A6U84_03435	COG1381	Involved in DNA repair and RecF pathway recombination
A6U84_03445	COG2226	methyltransferase
A6U84_03455	COG1418	mRNA catabolic process
A6U84_03465	COG0346	lactoylglutathione lyase activity
A6U84_03480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_03485	COG3443	Belongs to the bacterial solute-binding protein 9 family
A6U84_03490	COG0668	transmembrane transport
A6U84_03500	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
A6U84_03530	COG1742	UPF0060 membrane protein
A6U84_03550	COG1183	phosphatidylcholine synthase activity
A6U84_03555	COG0688	phosphatidylethanolamine metabolic process
A6U84_03560	COG5265	(ABC) transporter
A6U84_03605	COG2852	Protein conserved in bacteria
A6U84_03610	COG0215	cysteine-tRNA ligase activity
A6U84_03615	COG4221	oxidoreductase activity
A6U84_03620	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A6U84_03625	COG1286	toxin biosynthetic process
A6U84_03640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6U84_03650	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A6U84_03660	COG0305	Participates in initiation and elongation during chromosome replication
A6U84_03685	COG0359	binds to the 23S rRNA
A6U84_03695	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
A6U84_03700	COG0360	Binds together with S18 to 16S ribosomal RNA
A6U84_03705	COG0667	Aldo Keto reductase
A6U84_03710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A6U84_03720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6U84_03725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6U84_03730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A6U84_03735	COG1561	YicC-like family, N-terminal region
A6U84_03740	COG0194	GDP metabolic process
A6U84_03750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A6U84_03755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A6U84_03765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
A6U84_03780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A6U84_03805	COG0488	(ABC) transporter
A6U84_03810	COG3706	GGDEF domain
A6U84_03820	COG0105	UTP biosynthetic process
A6U84_03840	COG0314	molybdopterin synthase activity
A6U84_03850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A6U84_03855	COG0322	excinuclease ABC activity
A6U84_03860	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_03870	COG0625	glutathione transferase activity
A6U84_03885	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A6U84_03890	COG0243	molybdopterin cofactor binding
A6U84_03905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A6U84_03910	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A6U84_03915	COG0628	permease
A6U84_03925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
A6U84_03930	COG0248	Ppx GppA phosphatase
A6U84_03955	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
A6U84_03965	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
A6U84_03970	COG0477	Major facilitator Superfamily
A6U84_03975	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
A6U84_03980	COG4452	Inner membrane protein CreD
A6U84_03985	COG0659	secondary active sulfate transmembrane transporter activity
A6U84_03995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A6U84_04000	COG3654	unkown
A6U84_04005	COG2336	PFAM SpoVT AbrB
A6U84_04010	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
A6U84_04020	COG0113	porphobilinogen synthase activity
A6U84_04045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A6U84_04050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A6U84_04055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6U84_04055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A6U84_04065	COG1280	lysine exporter protein (LysE YggA)
A6U84_04070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A6U84_04075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6U84_04080	COG2814	Major facilitator Superfamily
A6U84_04085	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A6U84_04105	COG0416	fatty acid biosynthetic process
A6U84_04110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6U84_04115	COG0776	regulation of translation
A6U84_04150	COG0601	transmembrane transport
A6U84_04155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_04160	COG0444	Belongs to the ABC transporter superfamily
A6U84_04170	COG0747	negative chemotaxis
A6U84_04180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A6U84_04185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6U84_04200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A6U84_04205	COG0583	DNA-binding transcription factor activity
A6U84_04215	COG0737	Belongs to the 5'-nucleotidase family
A6U84_04240	COG2897	thiosulfate sulfurtransferase activity
A6U84_04255	COG0415	Belongs to the DNA photolyase family
A6U84_04265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6U84_04295	COG3932	Exopolysaccharide synthesis, ExoD
A6U84_04300	COG1238	metal cluster binding
A6U84_04315	COG4139	cobalamin transport
A6U84_04320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A6U84_04330	COG1528	Iron-storage protein
A6U84_04400	COG1612	heme a metabolic process
A6U84_04410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
A6U84_04415	COG0010	Belongs to the arginase family
A6U84_04420	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A6U84_04425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A6U84_04440	COG1832	CoA-binding protein
A6U84_04460	COG2199	diguanylate cyclase activity
A6U84_04465	COG0740	serine-type endopeptidase activity
A6U84_04470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
A6U84_04475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A6U84_04485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A6U84_04515	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6U84_04520	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6U84_04525	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6U84_04535	COG0649	NAD binding
A6U84_04545	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
A6U84_04550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A6U84_04560	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A6U84_04565	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A6U84_04575	COG0713	ATP synthesis coupled electron transport
A6U84_04590	COG1007	ATP synthesis coupled electron transport
A6U84_04595	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A6U84_04595	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A6U84_04610	COG0442	prolyl-tRNA aminoacylation
A6U84_04620	COG1136	(ABC) transporter
A6U84_04635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6U84_04645	COG0784	Response regulator, receiver
A6U84_04655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
A6U84_04660	COG0477	Major facilitator Superfamily
A6U84_04675	COG0557	exoribonuclease II activity
A6U84_04680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A6U84_04690	COG0758	DNA mediated transformation
A6U84_04695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
A6U84_04705	COG0540	Belongs to the ATCase OTCase family
A6U84_04710	COG1960	acyl-CoA dehydrogenase activity
A6U84_04715	COG0456	acetyltransferase
A6U84_04735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A6U84_04740	COG2824	Alkylphosphonate utilization operon protein PhnA
A6U84_04745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A6U84_04750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A6U84_04755	COG0154	amidase activity
A6U84_04760	COG3811	Belongs to the UPF0386 family
A6U84_04775	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A6U84_04785	COG0456	acetyltransferase
A6U84_04800	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A6U84_04810	COG0511	ligase activity, forming carbon-carbon bonds
A6U84_04815	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A6U84_04825	COG0436	Aminotransferase
A6U84_04845	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_04850	COG1530	ribonuclease E activity
A6U84_04860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A6U84_04880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A6U84_04885	COG0384	phenazine biosynthesis protein PhzF
A6U84_04900	COG0633	Ferredoxin
A6U84_04910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A6U84_04915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
A6U84_04920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A6U84_04930	COG3768	UPF0283 membrane protein
A6U84_04935	COG3106	COG3106 Predicted ATPase
A6U84_04965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A6U84_05000	COG0537	adenosine 5'-monophosphoramidase activity
A6U84_05030	COG0052	Belongs to the universal ribosomal protein uS2 family
A6U84_05035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
A6U84_05040	COG0528	UMP kinase activity
A6U84_05045	COG0233	cytoplasmic translational termination
A6U84_05050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A6U84_05060	COG0750	zinc metalloprotease
A6U84_05065	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6U84_05070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6U84_05075	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6U84_05080	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6U84_05085	COG3494	Protein of unknown function (DUF1009)
A6U84_05090	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A6U84_05095	COG0372	Belongs to the citrate synthase family
A6U84_05110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A6U84_05120	COG2877	3-deoxy-8-phosphooctulonate synthase activity
A6U84_05125	COG0148	phosphopyruvate hydratase activity
A6U84_05135	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A6U84_05140	COG0022	dehydrogenase e1 component
A6U84_05140	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6U84_05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6U84_05155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A6U84_05165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A6U84_05170	COG0697	spore germination
A6U84_05190	COG2867	negative regulation of translational initiation
A6U84_05200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
A6U84_05200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
A6U84_05210	COG3852	Histidine kinase
A6U84_05215	COG2204	response regulator
A6U84_05220	COG5000	phosphorelay sensor kinase activity
A6U84_05225	COG2204	response regulator
A6U84_05230	COG0569	domain protein
A6U84_05235	COG1923	regulation of RNA biosynthetic process
A6U84_05240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A6U84_05245	COG3956	TIGRFAM MazG family protein
A6U84_05255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A6U84_05255	COG1648	precorrin-2 dehydrogenase activity
A6U84_05295	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6U84_05295	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A6U84_05300	COG0509	glycine decarboxylation via glycine cleavage system
A6U84_05305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A6U84_05335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A6U84_05340	COG0564	pseudouridine synthase activity
A6U84_05345	COG0546	phosphoglycolate phosphatase activity
A6U84_05360	COG1309	transcriptional regulator
A6U84_05365	COG0251	oxidation-reduction process
A6U84_05370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A6U84_05380	COG1671	Belongs to the UPF0178 family
A6U84_05390	COG0450	alkyl hydroperoxide reductase
A6U84_05395	COG0625	glutathione transferase activity
A6U84_05440	COG2826	transposase and inactivated derivatives, IS30 family
A6U84_05445	COG0583	DNA-binding transcription factor activity
A6U84_05450	COG2828	Protein conserved in bacteria
A6U84_05465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_05470	COG0784	Response regulator, receiver
A6U84_05470	COG4191	Histidine kinase
A6U84_05475	COG0784	Response regulator, receiver
A6U84_05480	COG2202	Pas domain
A6U84_05480	COG3920	Histidine kinase
A6U84_05485	COG0784	Response regulator, receiver
A6U84_05485	COG4191	Histidine kinase
A6U84_05515	COG0673	inositol 2-dehydrogenase activity
A6U84_05525	COG1609	Transcriptional regulator
A6U84_05530	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_05535	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_05540	COG1129	ABC transporter
A6U84_05545	COG1879	ABC-type sugar transport system periplasmic component
A6U84_05550	COG0328	RNA-DNA hybrid ribonuclease activity
A6U84_05560	COG2226	methyltransferase
A6U84_05570	COG0321	lipoyl(octanoyl) transferase activity
A6U84_05570	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A6U84_05575	COG0084	hydrolase, TatD family'
A6U84_05580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6U84_05590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A6U84_05645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
A6U84_05650	COG2095	MarC family integral membrane protein
A6U84_05655	COG0617	tRNA 3'-terminal CCA addition
A6U84_05655	COG0517	IMP dehydrogenase activity
A6U84_05655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A6U84_05660	COG0629	single-stranded DNA binding
A6U84_05665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A6U84_05675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A6U84_05685	COG3685	Protein conserved in bacteria
A6U84_05690	COG0179	Fumarylacetoacetate (FAA) hydrolase
A6U84_05705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6U84_05710	COG1121	(ABC) transporter
A6U84_05730	COG0667	Aldo Keto reductase
A6U84_05740	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
A6U84_05815	COG2239	Acts as a magnesium transporter
A6U84_05820	COG0243	molybdopterin cofactor binding
A6U84_05830	COG0242	peptide deformylase activity
A6U84_05855	COG0321	lipoyl(octanoyl) transferase activity
A6U84_05860	COG1064	alcohol dehydrogenase
A6U84_05890	COG1862	Preprotein translocase
A6U84_05910	COG2124	cytochrome p450
A6U84_05925	COG0596	Alpha beta hydrolase
A6U84_05940	COG0626	cystathionine gamma-synthase activity
A6U84_05945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_05950	COG4597	amino acid ABC transporter
A6U84_05955	COG0765	amino acid transport
A6U84_05960	COG1126	abc transporter atp-binding protein
A6U84_05975	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A6U84_05990	COG0436	Aminotransferase
A6U84_06020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6U84_06030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6U84_06035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6U84_06040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A6U84_06055	COG3243	poly(R)-hydroxyalkanoic acid synthase
A6U84_06060	COG1489	DNA binding
A6U84_06065	COG0024	Methionine aminopeptidase
A6U84_06070	COG2003	Belongs to the UPF0758 family
A6U84_06085	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
A6U84_06100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A6U84_06105	COG0546	phosphoglycolate phosphatase activity
A6U84_06115	COG0114	fumarate hydratase activity
A6U84_06125	COG0504	CTP synthase activity
A6U84_06135	COG0149	triose-phosphate isomerase activity
A6U84_06145	COG0187	DNA topoisomerase II activity
A6U84_06155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6U84_06160	COG0745	RESPONSE REGULATOR receiver
A6U84_06180	COG3264	Mechanosensitive ion channel
A6U84_06180	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
A6U84_06245	COG1127	ABC transporter
A6U84_06250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A6U84_06255	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_06265	COG0280	phosphate acetyltransferase
A6U84_06265	COG0281	malic enzyme
A6U84_06275	COG0778	Nitroreductase
A6U84_06280	COG0823	Involved in the tonB-independent uptake of proteins
A6U84_06295	COG1368	sulfuric ester hydrolase activity
A6U84_06325	COG0544	peptidyl-prolyl cis-trans isomerase activity
A6U84_06345	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
A6U84_06365	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A6U84_06390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6U84_06390	COG0512	Glutamine amidotransferase of anthranilate synthase
A6U84_06395	COG0343	queuine tRNA-ribosyltransferase activity
A6U84_06400	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
A6U84_06415	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
A6U84_06435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6U84_06440	COG0134	indole-3-glycerol-phosphate synthase activity
A6U84_06445	COG0315	cyclic pyranopterin monophosphate synthase activity
A6U84_06450	COG0303	'Molybdopterin
A6U84_06455	COG3706	GGDEF domain
A6U84_06465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A6U84_06465	COG0475	glutathione-regulated potassium exporter activity
A6U84_06475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A6U84_06480	COG0697	spore germination
A6U84_06485	COG2814	Major facilitator Superfamily
A6U84_06490	COG0746	molybdenum cofactor guanylyltransferase activity
A6U84_06495	COG1763	Mo-molybdopterin cofactor biosynthetic process
A6U84_06500	COG0739	heme binding
A6U84_06505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A6U84_06510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A6U84_06515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A6U84_06520	COG0805	protein transport
A6U84_06525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6U84_06530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
A6U84_06535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A6U84_06540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A6U84_06545	COG1472	Belongs to the glycosyl hydrolase 3 family
A6U84_06555	COG0018	arginyl-trna synthetase
A6U84_06560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
A6U84_06565	COG0316	Belongs to the HesB IscA family
A6U84_06590	COG0525	valine-tRNA ligase activity
A6U84_06600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A6U84_06625	COG0655	NAD(P)H dehydrogenase (quinone) activity
A6U84_06630	COG1546	Belongs to the CinA family
A6U84_06630	COG1058	Belongs to the CinA family
A6U84_06635	COG0589	response to stress
A6U84_06640	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A6U84_06650	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A6U84_06665	COG1914	H( )-stimulated, divalent metal cation uptake system
A6U84_06675	COG1132	(ABC) transporter
A6U84_06680	COG0628	permease
A6U84_06715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A6U84_06725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
A6U84_06735	COG0302	gtp cyclohydrolase
A6U84_06740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A6U84_06745	COG1752	Esterase of the alpha-beta hydrolase superfamily
A6U84_06750	COG0517	IMP dehydrogenase activity
A6U84_06750	COG0516	GMP reductase activity
A6U84_06780	COG1760	l-serine dehydratase
A6U84_06815	COG0583	DNA-binding transcription factor activity
A6U84_06830	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A6U84_06830	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A6U84_06840	COG0347	Belongs to the P(II) protein family
A6U84_06845	COG0174	glutamine synthetase
A6U84_06875	COG0697	spore germination
A6U84_06885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A6U84_06895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A6U84_06925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A6U84_06930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A6U84_06935	COG2186	Transcriptional regulator
A6U84_06945	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6U84_06950	COG4603	Belongs to the binding-protein-dependent transport system permease family
A6U84_06955	COG3845	ABC transporter
A6U84_06960	COG1183	phosphatidylcholine synthase activity
A6U84_06965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A6U84_06970	COG0679	Auxin Efflux Carrier
A6U84_06975	COG0785	Cytochrome C biogenesis protein
A6U84_07005	COG0346	lactoylglutathione lyase activity
A6U84_07010	COG1278	Cold shock
A6U84_07065	COG1136	(ABC) transporter
A6U84_07065	COG0577	efflux transmembrane transporter activity
A6U84_07070	COG1136	(ABC) transporter
A6U84_07070	COG0577	efflux transmembrane transporter activity
A6U84_07085	COG2151	metal-sulfur cluster biosynthetic enzyme
A6U84_07090	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A6U84_07095	COG0719	Fe-S assembly protein
A6U84_07100	COG0396	ATPase activity
A6U84_07105	COG0719	Fe-S assembly protein
A6U84_07110	COG1104	cysteine desulfurase activity
A6U84_07115	COG2945	thiolester hydrolase activity
A6U84_07120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A6U84_07125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A6U84_07135	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A6U84_07140	COG2833	Protein of unknown function (DUF455)
A6U84_07145	COG0739	heme binding
A6U84_07150	COG0513	Belongs to the DEAD box helicase family
A6U84_07175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6U84_07185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A6U84_07190	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6U84_07195	COG0047	phosphoribosylformylglycinamidine synthase activity
A6U84_07210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6U84_07220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A6U84_07240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A6U84_07245	COG2814	Major facilitator Superfamily
A6U84_07250	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_07255	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_07260	COG0037	tRNA processing
A6U84_07265	COG2066	Belongs to the glutaminase family
A6U84_07270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A6U84_07275	COG0861	Integral membrane protein TerC family
A6U84_07295	COG1280	lysine exporter protein (LysE YggA)
A6U84_07305	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A6U84_07310	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A6U84_07320	COG0538	isocitrate dehydrogenase activity
A6U84_07335	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A6U84_07340	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
A6U84_07345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_07350	COG2313	pseudouridylate synthase activity
A6U84_07360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_07365	COG4215	(ABC) transporter
A6U84_07375	COG5425	PFAM Usg family protein
A6U84_07385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6U84_07390	COG1522	sequence-specific DNA binding
A6U84_07395	COG1573	uracil-dna glycosylase
A6U84_07405	COG2202	Pas domain
A6U84_07405	COG2205	protein histidine kinase activity
A6U84_07415	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A6U84_07420	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A6U84_07435	COG0842	Transport permease protein
A6U84_07440	COG1131	(ABC) transporter
A6U84_07445	COG0730	response to heat
A6U84_07455	COG0840	transmembrane signaling receptor activity
A6U84_07455	COG0840	transmembrane signaling receptor activity
A6U84_07465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A6U84_07470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A6U84_07485	COG0129	dihydroxy-acid dehydratase activity
A6U84_07490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
A6U84_07495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
A6U84_07505	COG3739	integral membrane protein
A6U84_07515	COG0203	ribosomal protein L17
A6U84_07520	COG0202	RNA polymerase activity
A6U84_07525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
A6U84_07530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A6U84_07535	COG0563	adenylate kinase activity
A6U84_07540	COG0201	protein transport
A6U84_07545	COG0200	Binds to the 23S rRNA
A6U84_07550	COG1841	ribosomal large subunit assembly
A6U84_07555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A6U84_07560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A6U84_07565	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A6U84_07570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A6U84_07575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
A6U84_07580	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A6U84_07585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
A6U84_07590	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A6U84_07595	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A6U84_07600	COG0255	Belongs to the universal ribosomal protein uL29 family
A6U84_07605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
A6U84_07610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A6U84_07615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A6U84_07620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A6U84_07625	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A6U84_07630	COG0089	rRNA binding
A6U84_07635	COG0088	Forms part of the polypeptide exit tunnel
A6U84_07640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A6U84_07645	COG0051	transcription antitermination factor activity, RNA binding
A6U84_07650	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A6U84_07655	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A6U84_07660	COG0049	tRNA binding
A6U84_07665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
A6U84_07680	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A6U84_07685	COG0085	RNA polymerase activity
A6U84_07695	COG0222	ribosome binding
A6U84_07700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
A6U84_07705	COG0081	regulation of translation
A6U84_07710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A6U84_07720	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
A6U84_07735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A6U84_07740	COG0861	Integral membrane protein TerC family
A6U84_07770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A6U84_07775	COG1607	acyl-coa hydrolase
A6U84_07800	COG2910	NAD(P)H-binding
A6U84_07805	COG1733	regulation of RNA biosynthetic process
A6U84_07815	COG0556	nucleotide-excision repair
A6U84_07820	COG2382	esterase
A6U84_07840	COG0484	heat shock protein binding
A6U84_07855	COG3706	GGDEF domain
A6U84_07865	COG3842	ATPase activity
A6U84_07875	COG1840	ABC-type Fe3 transport system, periplasmic component
A6U84_07880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6U84_07895	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
A6U84_07905	COG2207	Transcriptional regulator
A6U84_07910	COG1064	alcohol dehydrogenase
A6U84_07915	COG1252	NADH dehydrogenase
A6U84_07920	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A6U84_07925	COG2197	response regulator
A6U84_07930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A6U84_07935	COG1090	epimerase
A6U84_07975	COG0656	L-ascorbic acid biosynthetic process
A6U84_07990	COG0440	acetolactate synthase activity
A6U84_07995	COG0028	Belongs to the TPP enzyme family
A6U84_08005	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
A6U84_08010	COG3830	Belongs to the UPF0237 family
A6U84_08010	COG0560	Phosphoserine phosphatase
A6U84_08020	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_08030	COG0330	HflC and HflK could
A6U84_08035	COG0330	HflC and HflK could
A6U84_08045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A6U84_08050	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
A6U84_08090	COG0277	FAD linked oxidase domain protein
A6U84_08095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6U84_08150	COG1335	isochorismatase
A6U84_08170	COG0006	proline dipeptidase activity
A6U84_08180	COG2264	protein methyltransferase activity
A6U84_08185	COG1999	signal sequence binding
A6U84_08195	COG0835	chemotaxis
A6U84_08205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A6U84_08220	COG1247	-acetyltransferase
A6U84_08230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
A6U84_08235	COG1280	lysine exporter protein (LysE YggA)
A6U84_08240	COG0497	DNA recombination
A6U84_08245	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A6U84_08255	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A6U84_08260	COG0849	cell division
A6U84_08265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A6U84_08270	COG1181	Belongs to the D-alanine--D-alanine ligase family
A6U84_08275	COG0477	Major facilitator Superfamily
A6U84_08285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
A6U84_08290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A6U84_08295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A6U84_08305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
A6U84_08310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A6U84_08320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A6U84_08335	COG0275	rRNA processing
A6U84_08340	COG2001	Belongs to the MraZ family
A6U84_08345	COG3766	membrane
A6U84_08355	COG0754	glutathionylspermidine amidase activity
A6U84_08380	COG3023	N-Acetylmuramoyl-L-alanine amidase
A6U84_08410	COG4106	trans-aconitate 2-methyltransferase activity
A6U84_08430	COG2226	methyltransferase
A6U84_08440	COG2267	carboxylic ester hydrolase activity
A6U84_08445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A6U84_08460	COG0251	oxidation-reduction process
A6U84_08475	COG1376	ErfK ybiS ycfS ynhG family protein
A6U84_08480	COG2814	Major facilitator Superfamily
A6U84_08505	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_08510	COG0174	glutamine synthetase
A6U84_08515	COG0531	amino acid
A6U84_08525	COG1737	Transcriptional regulator
A6U84_08545	COG3842	ATPase activity
A6U84_08605	COG2968	Membrane
A6U84_08615	COG0432	Pfam Uncharacterised protein family UPF0047
A6U84_08630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A6U84_08635	COG0358	DNA primase activity
A6U84_08645	COG0505	Belongs to the CarA family
A6U84_08650	COG0534	Mate efflux family protein
A6U84_08665	COG2321	neutral zinc metallopeptidase
A6U84_08680	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
A6U84_08685	COG3706	GGDEF domain
A6U84_08690	COG1573	uracil-dna glycosylase
A6U84_08700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6U84_08710	COG1522	sequence-specific DNA binding
A6U84_08715	COG0492	ferredoxin-NADP+ reductase activity
A6U84_08720	COG0583	DNA-binding transcription factor activity
A6U84_08730	COG1902	pentaerythritol trinitrate reductase activity
A6U84_08755	COG0387	Pfam Sodium calcium exchanger
A6U84_08760	COG0436	Aminotransferase
A6U84_08765	COG2199	diguanylate cyclase activity
A6U84_08765	COG2200	EAL domain
A6U84_08780	COG1278	Cold shock
A6U84_08785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6U84_08795	COG1846	Transcriptional regulator
A6U84_08800	COG0745	RESPONSE REGULATOR receiver
A6U84_08805	COG2205	protein histidine kinase activity
A6U84_08810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6U84_08830	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
A6U84_08840	COG1496	oxidoreductase activity
A6U84_08855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A6U84_08865	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
A6U84_08880	COG0840	transmembrane signaling receptor activity
A6U84_08885	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_08895	COG5001	Diguanylate cyclase
A6U84_08895	COG3300	MHYT domain
A6U84_08900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
A6U84_08905	COG5001	Diguanylate cyclase
A6U84_08915	COG0193	aminoacyl-tRNA hydrolase activity
A6U84_08925	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A6U84_08945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A6U84_08950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A6U84_08960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
A6U84_08960	COG2857	Cytochrome c1
A6U84_08980	COG1132	(ABC) transporter
A6U84_08985	COG1132	(ABC) transporter
A6U84_08995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A6U84_09010	COG0408	coproporphyrinogen oxidase activity
A6U84_09025	COG0617	tRNA 3'-terminal CCA addition
A6U84_09040	COG0714	Associated with various cellular activities
A6U84_09060	COG0454	-acetyltransferase
A6U84_09065	COG0477	Major facilitator Superfamily
A6U84_09075	COG0435	Glutathione S-transferase
A6U84_09090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A6U84_09095	COG3135	benzoate transporter
A6U84_09100	COG4944	Protein of unknown function (DUF1109)
A6U84_09115	COG0740	serine-type endopeptidase activity
A6U84_09130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
A6U84_09135	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A6U84_09160	COG4175	Glycine betaine
A6U84_09175	COG1435	thymidine kinase activity
A6U84_09195	COG2862	Uncharacterized protein family, UPF0114
A6U84_09210	COG0512	Glutamine amidotransferase of anthranilate synthase
A6U84_09210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A6U84_09220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A6U84_09235	COG0366	Alpha amylase catalytic
A6U84_09240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_09255	COG1160	GTP binding
A6U84_09275	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A6U84_09285	COG0024	Methionine aminopeptidase
A6U84_09295	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_09305	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A6U84_09315	COG0583	DNA-binding transcription factor activity
A6U84_09330	COG0402	S-adenosylhomocysteine deaminase activity
A6U84_09355	COG1309	transcriptional regulator
A6U84_09360	COG1686	Belongs to the peptidase S11 family
A6U84_09370	COG2351	hydroxyisourate hydrolase activity
A6U84_09375	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
A6U84_09400	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
A6U84_09410	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A6U84_09410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_09415	COG5002	protein histidine kinase activity
A6U84_09415	COG0784	Response regulator, receiver
A6U84_09415	COG2205	protein histidine kinase activity
A6U84_09420	COG0513	Belongs to the DEAD box helicase family
A6U84_09430	COG2259	Doxx family
A6U84_09435	COG1376	ErfK ybiS ycfS ynhG family protein
A6U84_09445	COG2308	Evidence 4 Homologs of previously reported genes of
A6U84_09455	COG1305	Transglutaminase-like
A6U84_09485	COG4214	carbohydrate transport
A6U84_09490	COG1129	ABC transporter
A6U84_09495	COG4213	ABC transporter substrate-binding protein
A6U84_09530	COG0840	transmembrane signaling receptor activity
A6U84_09550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_09580	COG1215	transferase activity, transferring glycosyl groups
A6U84_09595	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
A6U84_09610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6U84_09615	COG2346	COG2346, Truncated hemoglobins
A6U84_09635	COG1309	transcriptional regulator
A6U84_09650	COG0494	nUDIX hydrolase
A6U84_09660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_09665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_09695	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
A6U84_09700	COG0830	nickel cation binding
A6U84_09705	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
A6U84_09720	COG0804	urea catabolic process
A6U84_09725	COG1442	glycosyl transferase family 8
A6U84_09730	COG3755	Protein conserved in bacteria
A6U84_09740	COG0832	Belongs to the urease beta subunit family
A6U84_09745	COG3813	Protein conserved in bacteria
A6U84_09750	COG0831	urea catabolic process
A6U84_09755	COG0829	nickel cation binding
A6U84_09770	COG0411	ABC transporter
A6U84_09780	COG0559	Belongs to the binding-protein-dependent transport system permease family
A6U84_09795	COG0174	glutamine synthetase
A6U84_09800	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_09805	COG0784	Response regulator, receiver
A6U84_09805	COG2198	Histidine kinase
A6U84_09805	COG5002	protein histidine kinase activity
A6U84_09850	COG1218	3'(2'),5'-bisphosphate nucleotidase
A6U84_09925	COG0564	pseudouridine synthase activity
A6U84_09940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A6U84_09950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A6U84_09975	COG0346	lactoylglutathione lyase activity
A6U84_09985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
A6U84_09995	COG2832	Protein of unknown function (DUF454)
A6U84_10000	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A6U84_10005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_10010	COG4558	Periplasmic binding protein
A6U84_10020	COG3721	Heme iron utilization protein
A6U84_10040	COG2205	protein histidine kinase activity
A6U84_10080	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_10085	COG4605	iron ion homeostasis
A6U84_10090	COG4604	ABC transporter, ATP-binding protein
A6U84_10095	COG0783	Belongs to the Dps family
A6U84_10110	COG0840	transmembrane signaling receptor activity
A6U84_10110	COG2972	Histidine kinase
A6U84_10115	COG0656	L-ascorbic acid biosynthetic process
A6U84_10120	COG2814	Major facilitator Superfamily
A6U84_10130	COG0583	DNA-binding transcription factor activity
A6U84_10135	COG0657	acetylesterase activity
A6U84_10140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_10160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A6U84_10165	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
A6U84_10170	COG0288	reversible hydration of carbon dioxide
A6U84_10180	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
A6U84_10195	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
A6U84_10200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6U84_10205	COG0778	Nitroreductase
A6U84_10210	COG2267	carboxylic ester hydrolase activity
A6U84_10215	COG0251	oxidation-reduction process
A6U84_10220	COG1335	isochorismatase
A6U84_10225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_10235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_10250	COG1175	transmembrane transport
A6U84_10255	COG0395	ABC-type sugar transport system, permease component
A6U84_10260	COG3842	ATPase activity
A6U84_10265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_10275	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6U84_10290	COG4608	Belongs to the ABC transporter superfamily
A6U84_10295	COG0444	Belongs to the ABC transporter superfamily
A6U84_10300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_10305	COG0601	transmembrane transport
A6U84_10325	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
A6U84_10325	COG0392	lysyltransferase activity
A6U84_10365	COG2159	amidohydrolase
A6U84_10370	COG1960	acyl-CoA dehydrogenase activity
A6U84_10395	COG0745	RESPONSE REGULATOR receiver
A6U84_10405	COG1902	pentaerythritol trinitrate reductase activity
A6U84_10405	COG0446	pyridine nucleotide-disulphide oxidoreductase
A6U84_10410	COG3842	ATPase activity
A6U84_10420	COG1840	ABC-type Fe3 transport system, periplasmic component
A6U84_10425	COG1840	ABC-type Fe3 transport system, periplasmic component
A6U84_10430	COG0745	RESPONSE REGULATOR receiver
A6U84_10445	COG1192	Involved in chromosome partitioning
A6U84_10450	COG2201	protein-glutamate methylesterase activity
A6U84_10455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
A6U84_10460	COG0835	chemotaxis
A6U84_10465	COG0840	transmembrane signaling receptor activity
A6U84_10470	COG0835	chemotaxis
A6U84_10475	COG0643	Histidine kinase
A6U84_10475	COG2198	Histidine kinase
A6U84_10545	COG0277	FAD linked oxidase domain protein
A6U84_10555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A6U84_10555	COG1017	nitric oxide dioxygenase activity
A6U84_10590	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A6U84_10600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_10605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6U84_10615	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
A6U84_10640	COG0583	DNA-binding transcription factor activity
A6U84_10645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_10650	COG0725	ABC transporter, periplasmic molybdate-binding protein
A6U84_10655	COG4149	molybdate abc transporter
A6U84_10660	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A6U84_10675	COG2022	thiamine diphosphate biosynthetic process
A6U84_10690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A6U84_10695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6U84_10705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A6U84_10725	COG1132	(ABC) transporter
A6U84_10730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6U84_10755	COG0438	transferase activity, transferring glycosyl groups
A6U84_10775	COG4166	transmembrane transport
A6U84_10780	COG0601	transmembrane transport
A6U84_10785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_10795	COG0438	transferase activity, transferring glycosyl groups
A6U84_10800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
A6U84_10805	COG3142	Participates in the control of copper homeostasis
A6U84_10810	COG2814	Major facilitator Superfamily
A6U84_10825	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_10830	COG1737	Transcriptional regulator
A6U84_10840	COG3842	ATPase activity
A6U84_10850	COG0395	ABC-type sugar transport system, permease component
A6U84_10865	COG2188	Transcriptional regulator
A6U84_10870	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A6U84_10875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
A6U84_10880	COG1940	carbohydrate kinase activity
A6U84_10890	COG0671	phosphoesterase, PA-phosphatase related
A6U84_10895	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
A6U84_10900	COG0156	8-amino-7-oxononanoate synthase activity
A6U84_10910	COG0729	surface antigen
A6U84_10920	COG0835	chemotaxis
A6U84_10930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A6U84_10935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
A6U84_10940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
A6U84_10945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
A6U84_10950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
A6U84_10955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A6U84_10970	COG4974	Belongs to the 'phage' integrase family
A6U84_10995	COG1280	lysine exporter protein (LysE YggA)
A6U84_11005	COG0508	dehydrogenase complex catalyzes the overall conversion of
A6U84_11010	COG0567	Dehydrogenase, E1 component
A6U84_11015	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
A6U84_11020	COG0045	succinate-CoA ligase (ADP-forming) activity
A6U84_11025	COG0039	L-malate dehydrogenase activity
A6U84_11030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A6U84_11070	COG2264	protein methyltransferase activity
A6U84_11085	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
A6U84_11090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A6U84_11095	COG0181	hydroxymethylbilane synthase activity
A6U84_11135	COG1872	DUF167
A6U84_11140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A6U84_11150	COG1217	gtp-binding protein TYPA
A6U84_11155	COG0339	signal peptide processing
A6U84_11165	COG1846	Transcriptional regulator
A6U84_11175	COG0137	argininosuccinate synthase activity
A6U84_11185	COG1280	lysine exporter protein (LysE YggA)
A6U84_11190	COG1122	ATPase activity
A6U84_11195	COG4120	Belongs to the binding-protein-dependent transport system permease family
A6U84_11205	COG0820	rRNA (adenine-C2-)-methyltransferase activity
A6U84_11220	COG2154	pterin-4-alpha-carbinolamine dehydratase
A6U84_11225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A6U84_11230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A6U84_11240	COG4181	ATPase activity
A6U84_11250	COG0670	Belongs to the BI1 family
A6U84_11265	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A6U84_11270	COG4133	protoheme IX ABC transporter activity
A6U84_11275	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6U84_11280	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
A6U84_11305	COG2917	probably involved in intracellular septation
A6U84_11310	COG0552	protein localization to endoplasmic reticulum
A6U84_11315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A6U84_11320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
A6U84_11330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A6U84_11335	COG0287	Prephenate dehydrogenase
A6U84_11335	COG1605	Chorismate mutase
A6U84_11340	COG0228	four-way junction DNA binding
A6U84_11345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A6U84_11350	COG0336	Belongs to the RNA methyltransferase TrmD family
A6U84_11360	COG0335	large ribosomal subunit rRNA binding
A6U84_11365	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
A6U84_11370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_11385	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
A6U84_11395	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
A6U84_11415	COG0488	(ABC) transporter
A6U84_11425	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
A6U84_11435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A6U84_11440	COG0142	geranyltranstransferase activity
A6U84_11445	COG2885	chlorophyll binding
A6U84_11450	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
A6U84_11455	COG2223	nitrite transmembrane transporter activity
A6U84_11460	COG1349	DNA-binding transcription factor activity
A6U84_11465	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
A6U84_11470	COG2197	response regulator
A6U84_11475	COG1132	(ABC) transporter
A6U84_11480	COG3459	Glycosyltransferase 36 associated
A6U84_11485	COG1473	amidohydrolase
A6U84_11490	COG0579	oxidoreductase
A6U84_11500	COG0129	dihydroxy-acid dehydratase activity
A6U84_11505	COG2084	Dehydrogenase
A6U84_11510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6U84_11515	COG0277	FAD linked oxidase domain protein
A6U84_11520	COG2186	Transcriptional regulator
A6U84_11530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A6U84_11535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A6U84_11540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6U84_11545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6U84_11560	COG0495	leucyl-tRNA aminoacylation
A6U84_11575	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A6U84_11580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A6U84_11590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A6U84_11595	COG1946	Acyl-CoA thioesterase
A6U84_11600	COG0347	Belongs to the P(II) protein family
A6U84_11605	COG0004	ammonium transporteR
A6U84_11610	COG1674	ftsk spoiiie
A6U84_11615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A6U84_11630	COG0745	RESPONSE REGULATOR receiver
A6U84_11640	COG1329	Transcriptional regulator
A6U84_11645	COG2902	Dehydrogenase
A6U84_11650	COG2270	Major facilitator Superfamily
A6U84_11665	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_11680	COG0494	nUDIX hydrolase
A6U84_11690	COG0793	Belongs to the peptidase S41A family
A6U84_11700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
A6U84_11705	COG0799	negative regulation of ribosome biogenesis
A6U84_11710	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
A6U84_11715	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
A6U84_11720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
A6U84_11725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A6U84_11740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A6U84_11745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
A6U84_11770	COG0066	3-isopropylmalate dehydratase activity
A6U84_11775	COG0473	3-isopropylmalate dehydrogenase activity
A6U84_11780	COG1858	cytochrome C peroxidase
A6U84_11785	COG1797	cobyrinic acid a,c-diamide synthase activity
A6U84_11790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A6U84_11790	COG1648	precorrin-2 dehydrogenase activity
A6U84_11795	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
A6U84_11860	COG1492	cobalamin metabolic process
A6U84_11875	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_11880	COG3254	rhamnose metabolic process
A6U84_11885	COG0246	Mannitol dehydrogenase
A6U84_11890	COG1063	alcohol dehydrogenase
A6U84_11910	COG4214	carbohydrate transport
A6U84_11915	COG1129	ABC transporter
A6U84_11920	COG2186	Transcriptional regulator
A6U84_11925	COG2721	sulfolactate sulfo-lyase activity
A6U84_11930	COG0138	bifunctional purine biosynthesis protein purh
A6U84_11940	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A6U84_11940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A6U84_11945	COG0501	Belongs to the peptidase M48B family
A6U84_11965	COG0357	Ribosomal RNA small subunit methyltransferase G
A6U84_11970	COG0445	tRNA wobble uridine modification
A6U84_11975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
A6U84_11980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
A6U84_11985	COG1981	membrane
A6U84_11990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
A6U84_11995	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
A6U84_12000	COG0424	maF-like protein
A6U84_12005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A6U84_12010	COG0237	dephospho-CoA kinase activity
A6U84_12020	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
A6U84_12025	COG3030	protein affecting phage T7 exclusion by the F plasmid
A6U84_12035	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
A6U84_12060	COG0179	Fumarylacetoacetate (FAA) hydrolase
A6U84_12075	COG0135	phosphoribosylanthranilate isomerase activity
A6U84_12080	COG0133	tryptophan synthase activity
A6U84_12085	COG0159	tryptophan synthase activity
A6U84_12090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
A6U84_12095	COG0285	dihydrofolate synthase activity
A6U84_12105	COG1074	ATP-dependent DNA helicase activity
A6U84_12115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A6U84_12120	COG0802	atpase or kinase
A6U84_12125	COG2205	protein histidine kinase activity
A6U84_12130	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A6U84_12135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6U84_12140	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
A6U84_12140	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A6U84_12145	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
A6U84_12150	COG0642	Histidine kinase
A6U84_12155	COG0745	RESPONSE REGULATOR receiver
A6U84_12160	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
A6U84_12170	COG1652	LysM domain
A6U84_12175	COG1072	(Pantothenic acid kinase))
A6U84_12180	COG0140	phosphoribosyl-ATP diphosphatase activity
A6U84_12185	COG0107	imidazoleglycerol-phosphate synthase activity
A6U84_12190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
A6U84_12195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6U84_12205	COG0131	Imidazoleglycerol-phosphate dehydratase
A6U84_12210	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
A6U84_12215	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
A6U84_12225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A6U84_12240	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
A6U84_12250	COG1643	Atp-dependent helicase
A6U84_12285	COG0514	ATP-dependent DNA helicase (RecQ)
A6U84_12310	COG1072	(Pantothenic acid kinase))
A6U84_12320	COG1780	Probably involved in ribonucleotide reductase function
A6U84_12340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A6U84_12365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_12380	COG1185	polyribonucleotide nucleotidyltransferase activity
A6U84_12385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
A6U84_12390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A6U84_12395	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
A6U84_12400	COG3064	Membrane
A6U84_12400	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A6U84_12415	COG0779	Required for maturation of 30S ribosomal subunits
A6U84_12420	COG2814	Major facilitator Superfamily
A6U84_12425	COG2951	lytic endotransglycosylase activity
A6U84_12430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A6U84_12440	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
A6U84_12445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A6U84_12460	COG2816	NAD+ diphosphatase activity
A6U84_12465	COG0077	Prephenate dehydratase
A6U84_12465	COG1605	Chorismate mutase
A6U84_12470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
A6U84_12475	COG3474	cytochrome
A6U84_12485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
A6U84_12490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A6U84_12495	COG1278	Cold shock
A6U84_12500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6U84_12510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6U84_12510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A6U84_12520	COG0333	Belongs to the bacterial ribosomal protein bL32 family
A6U84_12550	COG2900	Belongs to the SlyX family
A6U84_12560	COG0484	heat shock protein binding
A6U84_12565	COG0443	Heat shock 70 kDa protein
A6U84_12580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
A6U84_12585	COG1744	ABC transporter substrate-binding protein PnrA-like
A6U84_12590	COG3845	ABC transporter
A6U84_12595	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6U84_12600	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6U84_12605	COG0295	cytidine deaminase activity
A6U84_12615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A6U84_12620	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A6U84_12630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A6U84_12635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A6U84_12640	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
A6U84_12650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A6U84_12655	COG1845	cytochrome c oxidase, subunit III
A6U84_12660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A6U84_12665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A6U84_12670	COG0477	Major facilitator Superfamily
A6U84_12680	COG0067	glutamate synthase
A6U84_12680	COG0069	glutamate synthase activity
A6U84_12680	COG0070	glutamate synthase
A6U84_12685	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A6U84_12700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A6U84_12710	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
A6U84_12745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_12765	COG0848	biopolymer transport protein
A6U84_12775	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A6U84_12790	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
A6U84_12795	COG3454	Phosphonate metabolism
A6U84_12800	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
A6U84_12805	COG3639	organic phosphonate transmembrane transporter activity
A6U84_12810	COG3639	organic phosphonate transmembrane transporter activity
A6U84_12820	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
A6U84_12830	COG4778	phosphonate C-P lyase system protein PhnL
A6U84_12835	COG4107	phosphonate C-P lyase system protein PhnK
A6U84_12840	COG3627	carbon phosphorus lyase activity
A6U84_12845	COG3626	phosphonate metabolism
A6U84_12850	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
A6U84_12855	COG3624	Phosphonate C-P lyase system protein PhnG
A6U84_12860	COG2188	Transcriptional regulator
A6U84_12865	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
A6U84_12870	COG0837	glucose binding
A6U84_12875	COG1803	Methylglyoxal synthase
A6U84_12880	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
A6U84_12885	COG4166	transmembrane transport
A6U84_12890	COG4174	ABC transporter (Permease)
A6U84_12895	COG4239	(ABC) transporter, permease
A6U84_12900	COG4172	Belongs to the ABC transporter superfamily
A6U84_12905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_12910	COG0174	glutamine synthetase
A6U84_12915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_12920	COG3265	gluconokinase activity
A6U84_12925	COG1174	glycine betaine transport
A6U84_12930	COG1125	glycine betaine transport
A6U84_12935	COG1174	glycine betaine transport
A6U84_12940	COG1732	Glycine betaine
A6U84_12950	COG1959	2 iron, 2 sulfur cluster binding
A6U84_12955	COG1840	ABC-type Fe3 transport system, periplasmic component
A6U84_12975	COG0697	spore germination
A6U84_12990	COG0791	NLP P60 protein
A6U84_13000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A6U84_13005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
A6U84_13040	COG4964	Belongs to the GSP D family
A6U84_13080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A6U84_13085	COG3422	double-strand break repair
A6U84_13095	COG0697	spore germination
A6U84_13100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6U84_13130	COG0481	GTPase activity
A6U84_13135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6U84_13165	COG1917	Cupin 2, conserved barrel domain protein
A6U84_13165	COG2169	Transcriptional regulator
A6U84_13170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A6U84_13195	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
A6U84_13200	COG0291	Belongs to the bacterial ribosomal protein bL35 family
A6U84_13205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
A6U84_13215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
A6U84_13220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A6U84_13220	COG0072	phenylalanine-tRNA ligase activity
A6U84_13225	COG0667	Aldo Keto reductase
A6U84_13245	COG4977	sequence-specific DNA binding
A6U84_13270	COG1570	exodeoxyribonuclease VII activity
A6U84_13275	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_13285	COG1846	Transcriptional regulator
A6U84_13290	COG0697	spore germination
A6U84_13295	COG2309	aminopeptidase activity
A6U84_13305	COG1393	Belongs to the ArsC family
A6U84_13320	COG0519	Catalyzes the synthesis of GMP from XMP
A6U84_13320	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A6U84_13335	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
A6U84_13365	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A6U84_13375	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A6U84_13385	COG1968	undecaprenyl-diphosphatase activity
A6U84_13400	COG0284	orotidine-5'-phosphate decarboxylase activity
A6U84_13410	COG3963	phosphatidate phosphatase activity
A6U84_13420	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
A6U84_13440	COG1175	transmembrane transport
A6U84_13445	COG0395	ABC-type sugar transport system, permease component
A6U84_13450	COG3842	ATPase activity
A6U84_13460	COG0189	ligase activity
A6U84_13470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A6U84_13475	COG1280	lysine exporter protein (LysE YggA)
A6U84_13480	COG0756	dUTP diphosphatase activity
A6U84_13485	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A6U84_13490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A6U84_13505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A6U84_13510	COG2226	methyltransferase
A6U84_13515	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
A6U84_13520	COG1024	Enoyl-CoA hydratase
A6U84_13525	COG0268	Binds directly to 16S ribosomal RNA
A6U84_13545	COG2814	Major facilitator Superfamily
A6U84_13565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6U84_13565	COG0785	Cytochrome C biogenesis protein
A6U84_13575	COG0596	Alpha beta hydrolase
A6U84_13605	COG1764	response to oxidative stress
A6U84_13615	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A6U84_13625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6U84_13635	COG1414	Transcriptional regulator
A6U84_13650	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_13670	COG1522	sequence-specific DNA binding
A6U84_13705	COG0747	negative chemotaxis
A6U84_13710	COG0601	transmembrane transport
A6U84_13715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_13720	COG4172	Belongs to the ABC transporter superfamily
A6U84_13725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_13730	COG1027	Aspartate ammonia-lyase
A6U84_13735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_13740	COG1126	abc transporter atp-binding protein
A6U84_13745	COG0765	amino acid transport
A6U84_13750	COG0765	amino acid transport
A6U84_13755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_13770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_13775	COG1802	Transcriptional regulator
A6U84_13780	COG3842	ATPase activity
A6U84_13785	COG4209	transmembrane transport
A6U84_13790	COG0395	ABC-type sugar transport system, permease component
A6U84_13795	COG1653	transport
A6U84_13805	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_13815	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6U84_13825	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_13835	COG0071	Belongs to the small heat shock protein (HSP20) family
A6U84_13850	COG0438	transferase activity, transferring glycosyl groups
A6U84_13870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A6U84_13905	COG2197	response regulator
A6U84_13910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
A6U84_13915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6U84_13920	COG4310	Domain of unknown function (DUF2172)
A6U84_13925	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
A6U84_13935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A6U84_13940	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
A6U84_13945	COG2197	response regulator
A6U84_13970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6U84_14010	COG4178	(ABC) transporter
A6U84_14030	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
A6U84_14040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A6U84_14050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A6U84_14065	COG1177	transmembrane transport
A6U84_14070	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_14075	COG3842	ATPase activity
A6U84_14105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_14110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_14115	COG0601	transmembrane transport
A6U84_14120	COG0747	negative chemotaxis
A6U84_14150	COG1522	sequence-specific DNA binding
A6U84_14165	COG0477	Major facilitator Superfamily
A6U84_14170	COG0583	DNA-binding transcription factor activity
A6U84_14185	COG0583	DNA-binding transcription factor activity
A6U84_14195	COG0747	negative chemotaxis
A6U84_14200	COG0601	transmembrane transport
A6U84_14205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_14225	COG1278	Cold shock
A6U84_14245	COG5002	protein histidine kinase activity
A6U84_14245	COG2198	Histidine kinase
A6U84_14245	COG0784	Response regulator, receiver
A6U84_14255	COG0405	Gamma-glutamyltransferase
A6U84_14260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_14265	COG0601	transmembrane transport
A6U84_14270	COG0747	negative chemotaxis
A6U84_14275	COG2186	Transcriptional regulator
A6U84_14315	COG1595	DNA-templated transcription, initiation
A6U84_14325	COG0395	ABC-type sugar transport system, permease component
A6U84_14330	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_14340	COG3842	ATPase activity
A6U84_14350	COG0765	amino acid transport
A6U84_14355	COG0765	amino acid transport
A6U84_14360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_14365	COG2186	Transcriptional regulator
A6U84_14380	COG1063	alcohol dehydrogenase
A6U84_14385	COG3284	Transcriptional regulator
A6U84_14410	COG1653	transport
A6U84_14415	COG1175	transmembrane transport
A6U84_14420	COG0395	ABC-type sugar transport system, permease component
A6U84_14425	COG3842	ATPase activity
A6U84_14435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6U84_14440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_14445	COG1116	anion transmembrane transporter activity
A6U84_14450	COG0395	ABC-type sugar transport system, permease component
A6U84_14455	COG1175	transmembrane transport
A6U84_14485	COG1609	Transcriptional regulator
A6U84_14500	COG1082	Xylose isomerase domain protein TIM barrel
A6U84_14505	COG3842	ATPase activity
A6U84_14510	COG0395	ABC-type sugar transport system, permease component
A6U84_14515	COG1175	transmembrane transport
A6U84_14520	COG1653	transport
A6U84_14525	COG1309	transcriptional regulator
A6U84_14530	COG0673	inositol 2-dehydrogenase activity
A6U84_14545	COG0673	inositol 2-dehydrogenase activity
A6U84_14550	COG1278	Cold shock
A6U84_14560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A6U84_14595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A6U84_14600	COG1136	(ABC) transporter
A6U84_14600	COG0577	efflux transmembrane transporter activity
A6U84_14605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_14625	COG2205	protein histidine kinase activity
A6U84_14630	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A6U84_14645	COG3842	ATPase activity
A6U84_14650	COG0395	ABC-type sugar transport system, permease component
A6U84_14655	COG1175	transmembrane transport
A6U84_14675	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6U84_14680	COG3618	amidohydrolase
A6U84_14685	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_14690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_14695	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_14700	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
A6U84_14705	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6U84_14710	COG2186	Transcriptional regulator
A6U84_14725	COG0667	Aldo Keto reductase
A6U84_14760	COG2223	nitrite transmembrane transporter activity
A6U84_14765	COG0583	DNA-binding transcription factor activity
A6U84_14770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A6U84_14780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6U84_14785	COG2084	Dehydrogenase
A6U84_14800	COG1609	Transcriptional regulator
A6U84_14805	COG1063	alcohol dehydrogenase
A6U84_14810	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_14820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_14825	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
A6U84_14830	COG1175	transmembrane transport
A6U84_14835	COG0395	ABC-type sugar transport system, permease component
A6U84_14850	COG0395	ABC-type sugar transport system, permease component
A6U84_14860	COG2182	Extracellular solute-binding protein
A6U84_14865	COG0626	cystathionine gamma-synthase activity
A6U84_14875	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6U84_14885	COG1121	(ABC) transporter
A6U84_14890	COG0523	cobalamin synthesis protein
A6U84_14905	COG0523	cobalamin synthesis protein
A6U84_14910	COG1653	transport
A6U84_14915	COG1175	transmembrane transport
A6U84_14920	COG0395	ABC-type sugar transport system, permease component
A6U84_14925	COG3842	ATPase activity
A6U84_14935	COG3047	cAMP biosynthetic process
A6U84_14960	COG0583	DNA-binding transcription factor activity
A6U84_14965	COG1879	ABC-type sugar transport system periplasmic component
A6U84_14970	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_14975	COG1129	ABC transporter
A6U84_14980	COG3447	MASE1 domain protein
A6U84_14980	COG5002	protein histidine kinase activity
A6U84_14980	COG5001	Diguanylate cyclase
A6U84_14985	COG3257	ureidoglycine aminohydrolase activity
A6U84_14995	COG5001	Diguanylate cyclase
A6U84_15000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A6U84_15010	COG0747	negative chemotaxis
A6U84_15015	COG0601	transmembrane transport
A6U84_15020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_15030	COG4608	Belongs to the ABC transporter superfamily
A6U84_15035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A6U84_15045	COG0129	dihydroxy-acid dehydratase activity
A6U84_15050	COG1879	ABC-type sugar transport system periplasmic component
A6U84_15055	COG1129	ABC transporter
A6U84_15060	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_15065	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_15070	COG2186	Transcriptional regulator
A6U84_15085	COG0587	DNA-directed DNA polymerase activity
A6U84_15120	COG0673	inositol 2-dehydrogenase activity
A6U84_15130	COG3842	ATPase activity
A6U84_15135	COG0395	ABC-type sugar transport system, permease component
A6U84_15140	COG1175	transmembrane transport
A6U84_15145	COG1653	transport
A6U84_15150	COG1846	Transcriptional regulator
A6U84_15150	COG1940	carbohydrate kinase activity
A6U84_15155	COG0673	inositol 2-dehydrogenase activity
A6U84_15170	COG5001	Diguanylate cyclase
A6U84_15185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
A6U84_15190	COG2894	cell division
A6U84_15195	COG0850	regulation of cytokinetic process
A6U84_15200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A6U84_15205	COG2186	Transcriptional regulator
A6U84_15210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6U84_15220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A6U84_15225	COG1063	alcohol dehydrogenase
A6U84_15230	COG1312	Catalyzes the dehydration of D-mannonate
A6U84_15245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
A6U84_15250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A6U84_15250	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A6U84_15255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_15270	COG0625	glutathione transferase activity
A6U84_15275	COG4172	Belongs to the ABC transporter superfamily
A6U84_15280	COG1921	L-seryl-tRNASec selenium transferase activity
A6U84_15295	COG3964	amidohydrolase
A6U84_15305	COG0601	transmembrane transport
A6U84_15310	COG0747	negative chemotaxis
A6U84_15320	COG0438	transferase activity, transferring glycosyl groups
A6U84_15365	COG4989	oxidoreductase activity
A6U84_15375	COG2188	Transcriptional regulator
A6U84_15380	COG3842	ATPase activity
A6U84_15385	COG1653	transport
A6U84_15390	COG1175	transmembrane transport
A6U84_15395	COG0395	ABC-type sugar transport system, permease component
A6U84_15400	COG1501	Belongs to the glycosyl hydrolase 31 family
A6U84_15410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_15415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6U84_15420	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
A6U84_15425	COG0352	thiamine-phosphate diphosphorylase activity
A6U84_15430	COG0351	phosphomethylpyrimidine kinase
A6U84_15435	COG1522	sequence-specific DNA binding
A6U84_15440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A6U84_15445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_15460	COG2204	response regulator
A6U84_15465	COG4191	Histidine kinase
A6U84_15470	COG1301	dicarboxylic acid transport
A6U84_15480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6U84_15485	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_15495	COG1473	amidohydrolase
A6U84_15515	COG1215	transferase activity, transferring glycosyl groups
A6U84_15525	COG2942	2-epimerase
A6U84_15550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6U84_15590	COG3307	-O-antigen
A6U84_15595	COG1596	polysaccharide export
A6U84_15600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A6U84_15615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6U84_15620	COG0840	transmembrane signaling receptor activity
A6U84_15625	COG1376	ErfK ybiS ycfS ynhG family protein
A6U84_15635	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_15645	COG2094	Belongs to the DNA glycosylase MPG family
A6U84_15655	COG1609	Transcriptional regulator
A6U84_15660	COG1653	transport
A6U84_15675	COG3842	ATPase activity
A6U84_15685	COG0673	inositol 2-dehydrogenase activity
A6U84_15690	COG0602	queuosine metabolic process
A6U84_15695	COG0720	synthase
A6U84_15700	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A6U84_15710	COG0673	inositol 2-dehydrogenase activity
A6U84_15725	COG0395	ABC-type sugar transport system, permease component
A6U84_15730	COG1175	transmembrane transport
A6U84_15755	COG0583	DNA-binding transcription factor activity
A6U84_15760	COG0280	phosphate acetyltransferase
A6U84_15760	COG0281	malic enzyme
A6U84_15775	COG0765	amino acid transport
A6U84_15780	COG1126	abc transporter atp-binding protein
A6U84_15785	COG2079	MmgE PrpD family protein
A6U84_15790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_15800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_15815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
A6U84_15825	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A6U84_15830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A6U84_15835	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_15840	COG1129	ABC transporter
A6U84_15850	COG1473	amidohydrolase
A6U84_15855	COG0747	negative chemotaxis
A6U84_15865	COG4172	Belongs to the ABC transporter superfamily
A6U84_15870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_15875	COG0601	transmembrane transport
A6U84_15880	COG0583	DNA-binding transcription factor activity
A6U84_15885	COG1446	asparaginase
A6U84_15900	COG0747	negative chemotaxis
A6U84_15920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_15925	COG0601	transmembrane transport
A6U84_15930	COG2197	response regulator
A6U84_15935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_15940	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
A6U84_15960	COG1595	DNA-templated transcription, initiation
A6U84_15965	COG1120	ATPase activity
A6U84_15970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_15985	COG2226	methyltransferase
A6U84_15995	COG1120	ATPase activity
A6U84_16000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_16020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6U84_16030	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_16035	COG0473	3-isopropylmalate dehydrogenase activity
A6U84_16040	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_16045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_16075	COG0601	transmembrane transport
A6U84_16080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_16085	COG4172	Belongs to the ABC transporter superfamily
A6U84_16090	COG1522	sequence-specific DNA binding
A6U84_16105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_16110	COG1126	abc transporter atp-binding protein
A6U84_16125	COG1473	amidohydrolase
A6U84_16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16140	COG1959	2 iron, 2 sulfur cluster binding
A6U84_16150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6U84_16155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16175	COG1960	acyl-CoA dehydrogenase activity
A6U84_16185	COG0747	negative chemotaxis
A6U84_16200	COG0444	Belongs to the ABC transporter superfamily
A6U84_16210	COG0667	Aldo Keto reductase
A6U84_16220	COG0583	DNA-binding transcription factor activity
A6U84_16225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16240	COG0747	negative chemotaxis
A6U84_16245	COG1473	amidohydrolase
A6U84_16250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_16290	COG4608	Belongs to the ABC transporter superfamily
A6U84_16295	COG0444	Belongs to the ABC transporter superfamily
A6U84_16305	COG0601	transmembrane transport
A6U84_16315	COG2186	Transcriptional regulator
A6U84_16330	COG0300	oxidoreductase activity
A6U84_16340	COG3453	Protein conserved in bacteria
A6U84_16340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6U84_16345	COG0640	Transcriptional regulator
A6U84_16355	COG2391	methyltransferase activity
A6U84_16360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A6U84_16370	COG0022	dehydrogenase e1 component
A6U84_16380	COG1960	acyl-CoA dehydrogenase activity
A6U84_16385	COG0183	Belongs to the thiolase family
A6U84_16395	COG1960	acyl-CoA dehydrogenase activity
A6U84_16400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A6U84_16415	COG1024	Enoyl-CoA hydratase
A6U84_16420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
A6U84_16425	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A6U84_16430	COG4952	isomerase
A6U84_16435	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_16435	COG3347	Dehydrogenase
A6U84_16440	COG1349	DNA-binding transcription factor activity
A6U84_16450	COG1129	ABC transporter
A6U84_16455	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_16460	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_16465	COG3254	rhamnose metabolic process
A6U84_16480	COG2264	protein methyltransferase activity
A6U84_16485	COG5001	Diguanylate cyclase
A6U84_16500	COG4335	DNA alkylation repair
A6U84_16505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A6U84_16510	COG4208	sulfate ABC transporter
A6U84_16520	COG4150	thiosulfate binding
A6U84_16525	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
A6U84_16540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
A6U84_16550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6U84_16560	COG1040	competence protein
A6U84_16565	COG2226	methyltransferase
A6U84_16580	COG0494	nUDIX hydrolase
A6U84_16590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A6U84_16595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A6U84_16600	COG0653	protein targeting
A6U84_16670	COG2244	polysaccharide biosynthetic process
A6U84_16685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A6U84_16715	COG0438	transferase activity, transferring glycosyl groups
A6U84_16720	COG0438	transferase activity, transferring glycosyl groups
A6U84_16735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6U84_16740	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
A6U84_16740	COG2273	Hydrolase Family 16
A6U84_16755	COG3842	ATPase activity
A6U84_16760	COG3833	ABC-type maltose transport systems, permease component
A6U84_16815	COG1396	sequence-specific DNA binding
A6U84_16825	COG1129	ABC transporter
A6U84_16830	COG4214	carbohydrate transport
A6U84_16835	COG4213	ABC transporter substrate-binding protein
A6U84_16850	COG0346	lactoylglutathione lyase activity
A6U84_16855	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A6U84_16855	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A6U84_16860	COG4770	biotin carboxylase activity
A6U84_16870	COG0625	glutathione transferase activity
A6U84_16875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A6U84_16880	COG1396	sequence-specific DNA binding
A6U84_16880	COG3800	Transcriptional regulator
A6U84_16890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6U84_16900	COG0300	oxidoreductase activity
A6U84_16910	COG2096	Adenosyltransferase
A6U84_16920	COG2086	electron transfer activity
A6U84_16930	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6U84_16935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A6U84_16940	COG0165	Argininosuccinate lyase
A6U84_16975	COG2884	Cell division ATP-binding protein ftsE
A6U84_16995	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A6U84_17010	COG0287	Prephenate dehydrogenase
A6U84_17015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A6U84_17020	COG2226	methyltransferase
A6U84_17025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6U84_17040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
A6U84_17045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
A6U84_17080	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
A6U84_17085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A6U84_17095	COG4974	Belongs to the 'phage' integrase family
A6U84_17100	COG0825	malonyl-CoA metabolic process
A6U84_17105	COG3034	peptidoglycan biosynthetic process
A6U84_17110	COG0425	Belongs to the sulfur carrier protein TusA family
A6U84_17115	COG0523	cobalamin synthesis protein
A6U84_17120	COG1686	Belongs to the peptidase S11 family
A6U84_17125	COG1473	amidohydrolase
A6U84_17135	COG4953	penicillin-binding protein 1C
A6U84_17140	COG2373	Large extracellular alpha-helical protein
A6U84_17145	COG2835	tetraacyldisaccharide 4'-kinase activity
A6U84_17155	COG3118	belongs to the thioredoxin family
A6U84_17175	COG0482	sulfurtransferase activity
A6U84_17190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A6U84_17205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A6U84_17210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A6U84_17215	COG0037	tRNA processing
A6U84_17225	COG2885	chlorophyll binding
A6U84_17230	COG0823	Involved in the tonB-independent uptake of proteins
A6U84_17250	COG0824	Thioesterase
A6U84_17260	COG0494	nUDIX hydrolase
A6U84_17275	COG2255	four-way junction helicase activity
A6U84_17280	COG0632	four-way junction helicase activity
A6U84_17285	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
A6U84_17290	COG2972	Histidine kinase
A6U84_17290	COG0840	transmembrane signaling receptor activity
A6U84_17295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_17300	COG0217	transcriptional regulatory protein
A6U84_17315	COG1692	metallophosphoesterase
A6U84_17325	COG1253	flavin adenine dinucleotide binding
A6U84_17365	COG0126	phosphoglycerate kinase activity
A6U84_17370	COG3588	fructose-bisphosphate aldolase
A6U84_17395	COG0254	rRNA binding
A6U84_17400	COG1132	(ABC) transporter
A6U84_17420	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_17450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A6U84_17455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A6U84_17460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
A6U84_17465	COG0457	Tetratricopeptide repeat
A6U84_17470	COG3750	Belongs to the UPF0335 family
A6U84_17490	COG0469	pyruvate kinase activity
A6U84_17495	COG3108	Peptidase M15
A6U84_17500	COG2204	response regulator
A6U84_17505	COG1164	Oligoendopeptidase f
A6U84_17510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A6U84_17520	COG5310	Homospermidine synthase
A6U84_17530	COG0737	Belongs to the 5'-nucleotidase family
A6U84_17535	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
A6U84_17540	COG0330	HflC and HflK could
A6U84_17565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6U84_17570	COG2951	lytic endotransglycosylase activity
A6U84_17585	COG2205	protein histidine kinase activity
A6U84_17600	COG0067	glutamate synthase
A6U84_17600	COG0069	glutamate synthase activity
A6U84_17600	COG0070	glutamate synthase
A6U84_17615	COG2205	protein histidine kinase activity
A6U84_17620	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
A6U84_17625	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A6U84_17635	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A6U84_17650	COG0252	asparaginase activity
A6U84_17660	COG1027	Aspartate ammonia-lyase
A6U84_17665	COG2186	Transcriptional regulator
A6U84_17690	COG3239	Fatty acid desaturase
A6U84_17710	COG0583	DNA-binding transcription factor activity
A6U84_17730	COG3842	ATPase activity
A6U84_17735	COG1177	transmembrane transport
A6U84_17755	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_17760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_17770	COG2267	carboxylic ester hydrolase activity
A6U84_17785	COG1126	abc transporter atp-binding protein
A6U84_17790	COG0765	amino acid transport
A6U84_17810	COG0174	glutamine synthetase
A6U84_17815	COG0069	glutamate synthase activity
A6U84_17820	COG2218	PFAM glutamate synthase alpha subunit domain protein
A6U84_17825	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A6U84_17845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_17855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_17860	COG0601	transmembrane transport
A6U84_17865	COG0747	negative chemotaxis
A6U84_17875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
A6U84_17880	COG1454	alcohol dehydrogenase
A6U84_17930	COG2308	Evidence 4 Homologs of previously reported genes of
A6U84_17930	COG2307	Protein conserved in bacteria
A6U84_17945	COG0488	(ABC) transporter
A6U84_17950	COG1304	FMN binding
A6U84_17955	COG1846	Transcriptional regulator
A6U84_17960	COG2972	Histidine kinase
A6U84_17960	COG0840	transmembrane signaling receptor activity
A6U84_17965	COG1070	Carbohydrate kinase
A6U84_17970	COG1830	Aldolase
A6U84_17975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
A6U84_17980	COG0667	Aldo Keto reductase
A6U84_17990	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_17995	COG1129	ABC transporter
A6U84_18000	COG1879	ABC-type sugar transport system periplasmic component
A6U84_18030	COG0071	Belongs to the small heat shock protein (HSP20) family
A6U84_18045	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A6U84_18060	COG0395	ABC-type sugar transport system, permease component
A6U84_18070	COG3842	ATPase activity
A6U84_18075	COG3842	ATPase activity
A6U84_18090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A6U84_18090	COG1648	precorrin-2 dehydrogenase activity
A6U84_18095	COG0243	molybdopterin cofactor binding
A6U84_18105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A6U84_18110	COG1116	anion transmembrane transporter activity
A6U84_18115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_18120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6U84_18130	COG3707	response regulator
A6U84_18135	COG1802	Transcriptional regulator
A6U84_18140	COG1914	H( )-stimulated, divalent metal cation uptake system
A6U84_18145	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A6U84_18150	COG4336	lyase activity
A6U84_18155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A6U84_18160	COG4770	biotin carboxylase activity
A6U84_18165	COG0366	Alpha amylase catalytic
A6U84_18175	COG4771	TonB-dependent receptor
A6U84_18180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A6U84_18200	COG1414	Transcriptional regulator
A6U84_18205	COG1475	DNA binding
A6U84_18210	COG1192	Involved in chromosome partitioning
A6U84_18240	COG0596	Alpha beta hydrolase
A6U84_18245	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A6U84_18255	COG2986	histidine ammonia-lyase
A6U84_18260	COG1228	amidohydrolase
A6U84_18265	COG0402	S-adenosylhomocysteine deaminase activity
A6U84_18305	COG0511	ligase activity, forming carbon-carbon bonds
A6U84_18310	COG0439	Biotin carboxylase
A6U84_18325	COG1984	allophanate hydrolase subunit 2
A6U84_18330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A6U84_18335	COG0436	Aminotransferase
A6U84_18345	COG4221	oxidoreductase activity
A6U84_18350	COG0765	amino acid transport
A6U84_18355	COG0765	amino acid transport
A6U84_18360	COG1126	abc transporter atp-binding protein
A6U84_18365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_18370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A6U84_18375	COG0010	Belongs to the arginase family
A6U84_18380	COG1126	abc transporter atp-binding protein
A6U84_18390	COG0765	amino acid transport
A6U84_18405	COG0640	Transcriptional regulator
A6U84_18415	COG0431	NADPH-dependent FMN reductase
A6U84_18425	COG0798	PFAM Bile acid sodium symporter
A6U84_18435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A6U84_18440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6U84_18450	COG3842	ATPase activity
A6U84_18455	COG0395	ABC-type sugar transport system, permease component
A6U84_18460	COG1175	transmembrane transport
A6U84_18470	COG0673	inositol 2-dehydrogenase activity
A6U84_18475	COG0673	inositol 2-dehydrogenase activity
A6U84_18515	COG0583	DNA-binding transcription factor activity
A6U84_18520	COG0477	Major facilitator Superfamily
A6U84_18530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_18540	COG4172	Belongs to the ABC transporter superfamily
A6U84_18545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_18550	COG0601	transmembrane transport
A6U84_18565	COG0277	FAD linked oxidase domain protein
A6U84_18585	COG2205	protein histidine kinase activity
A6U84_18590	COG0745	RESPONSE REGULATOR receiver
A6U84_18595	COG0671	phosphoesterase, PA-phosphatase related
A6U84_18645	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
A6U84_18650	COG0156	8-amino-7-oxononanoate synthase activity
A6U84_18655	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
A6U84_18660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6U84_18665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A6U84_18680	COG0010	Belongs to the arginase family
A6U84_18690	COG0697	spore germination
A6U84_18695	COG0673	inositol 2-dehydrogenase activity
A6U84_18715	COG0477	Major facilitator Superfamily
A6U84_18720	COG0642	Histidine kinase
A6U84_18730	COG2194	sulfuric ester hydrolase activity
A6U84_18740	COG0583	DNA-binding transcription factor activity
A6U84_18745	COG4774	siderophore transport
A6U84_18760	COG1120	ATPase activity
A6U84_18775	COG2137	regulation of response to DNA damage stimulus
A6U84_18780	COG3386	PFAM SMP-30 Gluconolaconase
A6U84_18790	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_18795	COG1129	ABC transporter
A6U84_18800	COG1879	ABC-type sugar transport system periplasmic component
A6U84_18805	COG4372	Transposase
A6U84_18810	COG3436	PFAM IS66 Orf2 family protein
A6U84_18815	COG2963	transposase activity
A6U84_18835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A6U84_18865	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A6U84_18870	COG4585	Histidine kinase
A6U84_18875	COG2197	response regulator
A6U84_18885	COG2133	pyrroloquinoline quinone binding
A6U84_18895	COG0500	methyltransferase
A6U84_18900	COG0564	pseudouridine synthase activity
A6U84_18915	COG0517	IMP dehydrogenase activity
A6U84_18915	COG4175	Glycine betaine
A6U84_18920	COG4176	ABC-type proline glycine betaine transport system permease component
A6U84_18930	COG4191	Histidine kinase
A6U84_18930	COG0784	Response regulator, receiver
A6U84_18940	COG0489	protein tyrosine kinase activity
A6U84_18940	COG3206	protein involved in exopolysaccharide biosynthesis
A6U84_18945	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A6U84_18950	COG1215	transferase activity, transferring glycosyl groups
A6U84_18955	COG1215	transferase activity, transferring glycosyl groups
A6U84_18960	COG1215	transferase activity, transferring glycosyl groups
A6U84_18965	COG0438	transferase activity, transferring glycosyl groups
A6U84_18970	COG2273	Hydrolase Family 16
A6U84_18975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
A6U84_18980	COG2244	polysaccharide biosynthetic process
A6U84_18985	COG0463	Glycosyl transferase, family 2
A6U84_18990	COG2327	Polysaccharide pyruvyl transferase
A6U84_18995	COG1215	transferase activity, transferring glycosyl groups
A6U84_19015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
A6U84_19020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_19035	COG0446	pyridine nucleotide-disulphide oxidoreductase
A6U84_19035	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A6U84_19060	COG1523	belongs to the glycosyl hydrolase 13 family
A6U84_19065	COG0033	Phosphoglucomutase
A6U84_19070	COG0297	glycogen (starch) synthase activity
A6U84_19075	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A6U84_19080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A6U84_19085	COG0058	SHG alpha-glucan phosphorylase activity
A6U84_19095	COG1794	racemase activity, acting on amino acids and derivatives
A6U84_19100	COG1522	sequence-specific DNA binding
A6U84_19110	COG2084	Dehydrogenase
A6U84_19115	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_19120	COG1063	alcohol dehydrogenase
A6U84_19130	COG4988	ABC transporter
A6U84_19135	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
A6U84_19145	COG1294	oxidase, subunit
A6U84_19175	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A6U84_19180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A6U84_19210	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A6U84_19215	COG0539	negative regulation of cytoplasmic translation
A6U84_19245	COG4221	oxidoreductase activity
A6U84_19250	COG0006	proline dipeptidase activity
A6U84_19255	COG0747	negative chemotaxis
A6U84_19260	COG0601	transmembrane transport
A6U84_19265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_19270	COG0444	Belongs to the ABC transporter superfamily
A6U84_19275	COG4608	Belongs to the ABC transporter superfamily
A6U84_19290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_19305	COG0411	ABC transporter
A6U84_19315	COG0559	Belongs to the binding-protein-dependent transport system permease family
A6U84_19335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A6U84_19340	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_19360	COG4993	Dehydrogenase
A6U84_19365	COG3685	Protein conserved in bacteria
A6U84_19375	COG0693	protein deglycase activity
A6U84_19400	COG0189	ligase activity
A6U84_19405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A6U84_19410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
A6U84_19420	COG0435	Glutathione S-transferase
A6U84_19425	COG0583	DNA-binding transcription factor activity
A6U84_19430	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_19435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A6U84_19440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A6U84_19445	COG1116	anion transmembrane transporter activity
A6U84_19455	COG1522	sequence-specific DNA binding
A6U84_19470	COG0784	Response regulator, receiver
A6U84_19490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A6U84_19510	COG0019	diaminopimelate decarboxylase activity
A6U84_19525	COG0527	aspartate kinase activity
A6U84_19535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
A6U84_19540	COG2890	protein-(glutamine-N5) methyltransferase activity
A6U84_19550	COG0542	response to heat
A6U84_19555	COG0741	lytic transglycosylase activity
A6U84_19555	COG1196	nuclear chromosome segregation
A6U84_19555	COG0739	heme binding
A6U84_19595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A6U84_19600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A6U84_19615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A6U84_19625	COG1309	transcriptional regulator
A6U84_19630	COG4221	oxidoreductase activity
A6U84_19635	COG1902	pentaerythritol trinitrate reductase activity
A6U84_19640	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_19645	COG0604	alcohol dehydrogenase
A6U84_19655	COG0243	molybdopterin cofactor binding
A6U84_19660	COG2814	Major facilitator Superfamily
A6U84_19670	COG0492	ferredoxin-NADP+ reductase activity
A6U84_19680	COG4566	intracellular signal transduction
A6U84_19685	COG4566	intracellular signal transduction
A6U84_19695	COG2140	Oxalate decarboxylase
A6U84_19700	COG0783	Belongs to the Dps family
A6U84_19710	COG0583	DNA-binding transcription factor activity
A6U84_19720	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_19725	COG1846	Transcriptional regulator
A6U84_19740	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
A6U84_19745	COG0583	DNA-binding transcription factor activity
A6U84_19750	COG0346	lactoylglutathione lyase activity
A6U84_19770	COG1574	metal-dependent hydrolase with the TIM-barrel fold
A6U84_19795	COG2080	2 iron, 2 sulfur cluster binding
A6U84_19800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
A6U84_19805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A6U84_19810	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
A6U84_19815	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
A6U84_19835	COG1278	Cold shock
A6U84_19865	COG2986	histidine ammonia-lyase
A6U84_19885	COG4172	Belongs to the ABC transporter superfamily
A6U84_19890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_19895	COG0601	transmembrane transport
A6U84_19900	COG4166	transmembrane transport
A6U84_19905	COG0840	transmembrane signaling receptor activity
A6U84_19915	COG3300	MHYT domain
A6U84_19915	COG5001	Diguanylate cyclase
A6U84_19935	COG1609	Transcriptional regulator
A6U84_19950	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_19955	COG1735	metal-dependent hydrolase with the TIM-barrel fold
A6U84_19980	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
A6U84_19985	COG1049	propionate catabolic process, 2-methylcitrate cycle
A6U84_19995	COG0367	asparagine synthase
A6U84_20005	COG0318	PFAM AMP-dependent synthetase and ligase
A6U84_20010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A6U84_20030	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A6U84_20030	COG0446	pyridine nucleotide-disulphide oxidoreductase
A6U84_20035	COG4311	Sarcosine oxidase, delta subunit
A6U84_20040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_20045	COG4977	sequence-specific DNA binding
A6U84_20050	COG1129	ABC transporter
A6U84_20060	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_20075	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_20080	COG0246	Mannitol dehydrogenase
A6U84_20085	COG1312	Catalyzes the dehydration of D-mannonate
A6U84_20105	COG1309	transcriptional regulator
A6U84_20110	COG1063	alcohol dehydrogenase
A6U84_20120	COG1879	ABC-type sugar transport system periplasmic component
A6U84_20130	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_20150	COG0477	Major facilitator Superfamily
A6U84_20160	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_20185	COG1178	ABC-type Fe3 transport system permease component
A6U84_20190	COG3842	ATPase activity
A6U84_20220	COG1253	flavin adenine dinucleotide binding
A6U84_20235	COG3842	ATPase activity
A6U84_20240	COG0395	ABC-type sugar transport system, permease component
A6U84_20245	COG1175	transmembrane transport
A6U84_20250	COG1653	transport
A6U84_20260	COG0673	inositol 2-dehydrogenase activity
A6U84_20265	COG1609	Transcriptional regulator
A6U84_20280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_20290	COG0446	pyridine nucleotide-disulphide oxidoreductase
A6U84_20290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
A6U84_20310	COG0668	transmembrane transport
A6U84_20340	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_20345	COG3433	isochorismatase activity
A6U84_20345	COG1535	isochorismatase
A6U84_20350	COG1021	2,3-dihydroxybenzoate-AMP ligase
A6U84_20355	COG1169	isochorismate synthase
A6U84_20365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A6U84_20365	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
A6U84_20370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A6U84_20380	COG2375	cellular response to nickel ion
A6U84_20390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_20395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_20400	COG1120	ATPase activity
A6U84_20405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_20415	COG1629	transport
A6U84_20415	COG4774	siderophore transport
A6U84_20420	COG1960	acyl-CoA dehydrogenase activity
A6U84_20425	COG0583	DNA-binding transcription factor activity
A6U84_20430	COG1609	Transcriptional regulator
A6U84_20440	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_20460	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A6U84_20470	COG1473	amidohydrolase
A6U84_20485	COG0747	negative chemotaxis
A6U84_20490	COG0601	transmembrane transport
A6U84_20495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_20500	COG0444	Belongs to the ABC transporter superfamily
A6U84_20505	COG4608	Belongs to the ABC transporter superfamily
A6U84_20510	COG0583	DNA-binding transcription factor activity
A6U84_20515	COG0747	negative chemotaxis
A6U84_20525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_20535	COG0693	protein deglycase activity
A6U84_20545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_20550	COG0601	transmembrane transport
A6U84_20560	COG1473	amidohydrolase
A6U84_20565	COG4172	Belongs to the ABC transporter superfamily
A6U84_20570	COG2390	Transcriptional regulator
A6U84_20580	COG1175	transmembrane transport
A6U84_20585	COG0395	ABC-type sugar transport system, permease component
A6U84_20630	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A6U84_20640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A6U84_20645	COG1414	Transcriptional regulator
A6U84_20650	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_20655	COG5487	UPF0391 membrane protein
A6U84_20660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6U84_20665	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A6U84_20670	COG1121	(ABC) transporter
A6U84_20675	COG0803	Belongs to the bacterial solute-binding protein 9 family
A6U84_20685	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
A6U84_20690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A6U84_20695	COG0471	metal ion transport
A6U84_20695	COG3273	potassium ion transport
A6U84_20700	COG1253	flavin adenine dinucleotide binding
A6U84_20705	COG1309	transcriptional regulator
A6U84_20720	COG1609	Transcriptional regulator
A6U84_20725	COG1070	Carbohydrate kinase
A6U84_20730	COG2115	Belongs to the xylose isomerase family
A6U84_20740	COG0778	Nitroreductase
A6U84_20745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A6U84_20750	COG2011	ABC-type metal ion transport system permease component
A6U84_20760	COG3300	MHYT domain
A6U84_20760	COG5001	Diguanylate cyclase
A6U84_20765	COG1054	Belongs to the UPF0176 family
A6U84_20775	COG2954	triphosphatase activity
A6U84_20780	COG0800	Aldolase
A6U84_20800	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
A6U84_20835	COG0523	cobalamin synthesis protein
A6U84_20845	COG1846	Transcriptional regulator
A6U84_20850	COG1609	Transcriptional regulator
A6U84_20855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6U84_20860	COG0673	inositol 2-dehydrogenase activity
A6U84_20865	COG3718	enzyme involved in inositol metabolism
A6U84_20875	COG3962	Belongs to the TPP enzyme family
A6U84_20880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_20890	COG3842	ATPase activity
A6U84_20910	COG0683	leucine binding
A6U84_20925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_20935	COG0747	negative chemotaxis
A6U84_20950	COG1082	Xylose isomerase domain protein TIM barrel
A6U84_20950	COG3185	4-Hydroxyphenylpyruvate dioxygenase
A6U84_20960	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
A6U84_20965	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A6U84_20970	COG1126	abc transporter atp-binding protein
A6U84_20975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_20980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_20985	COG0765	amino acid transport
A6U84_20990	COG0765	amino acid transport
A6U84_20995	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A6U84_21000	COG3485	protocatechuate 3,4-dioxygenase
A6U84_21005	COG3485	protocatechuate 3,4-dioxygenase
A6U84_21010	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A6U84_21020	COG0583	DNA-binding transcription factor activity
A6U84_21035	COG1414	Transcriptional regulator
A6U84_21045	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A6U84_21050	COG0183	Belongs to the thiolase family
A6U84_21055	COG1609	Transcriptional regulator
A6U84_21065	COG1082	Xylose isomerase domain protein TIM barrel
A6U84_21070	COG0673	inositol 2-dehydrogenase activity
A6U84_21080	COG1609	Transcriptional regulator
A6U84_21085	COG0395	ABC-type sugar transport system, permease component
A6U84_21090	COG1175	transmembrane transport
A6U84_21095	COG3842	ATPase activity
A6U84_21105	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
A6U84_21135	COG3842	ATPase activity
A6U84_21140	COG4149	molybdate abc transporter
A6U84_21145	COG1177	transmembrane transport
A6U84_21150	COG0584	glycerophosphoryl diester phosphodiesterase
A6U84_21155	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_21170	COG3842	ATPase activity
A6U84_21175	COG1177	transmembrane transport
A6U84_21190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A6U84_21230	COG3210	domain, Protein
A6U84_21230	COG3210	domain, Protein
A6U84_21265	COG0443	Heat shock 70 kDa protein
A6U84_21285	COG0385	Bile acid
A6U84_21300	COG2942	2-epimerase
A6U84_21355	COG3547	Transposase (IS116 IS110 IS902 family)
A6U84_21380	COG1132	(ABC) transporter
A6U84_21385	COG0438	transferase activity, transferring glycosyl groups
A6U84_21400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_21405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_21410	COG1120	ATPase activity
A6U84_21415	COG4774	siderophore transport
A6U84_21420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A6U84_21435	COG1609	Transcriptional regulator
A6U84_21440	COG1233	COG1233 Phytoene dehydrogenase and related
A6U84_21455	COG0395	ABC-type sugar transport system, permease component
A6U84_21460	COG3842	ATPase activity
A6U84_21465	COG4608	Belongs to the ABC transporter superfamily
A6U84_21470	COG0444	Belongs to the ABC transporter superfamily
A6U84_21475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_21480	COG0601	transmembrane transport
A6U84_21485	COG2186	Transcriptional regulator
A6U84_21495	COG0747	negative chemotaxis
A6U84_21505	COG5001	Diguanylate cyclase
A6U84_21505	COG3300	MHYT domain
A6U84_21510	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_21520	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A6U84_21530	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
A6U84_21535	COG0306	phosphate transporter
A6U84_21540	COG1392	Phosphate transport regulator
A6U84_21560	COG0745	RESPONSE REGULATOR receiver
A6U84_21565	COG5002	protein histidine kinase activity
A6U84_21580	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
A6U84_21595	COG4774	siderophore transport
A6U84_21605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_21610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_21615	COG1120	ATPase activity
A6U84_21620	COG1733	regulation of RNA biosynthetic process
A6U84_21645	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_21650	COG0583	DNA-binding transcription factor activity
A6U84_21660	COG3119	arylsulfatase activity
A6U84_21665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A6U84_21670	COG3842	ATPase activity
A6U84_21675	COG0165	Argininosuccinate lyase
A6U84_21680	COG0395	ABC-type sugar transport system, permease component
A6U84_21685	COG1175	transmembrane transport
A6U84_21690	COG2182	Extracellular solute-binding protein
A6U84_21695	COG1940	carbohydrate kinase activity
A6U84_21720	COG1486	melibiose metabolic process
A6U84_21725	COG0747	negative chemotaxis
A6U84_21730	COG0601	transmembrane transport
A6U84_21735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_21740	COG4172	Belongs to the ABC transporter superfamily
A6U84_21745	COG1486	melibiose metabolic process
A6U84_21750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_21755	COG0842	Transport permease protein
A6U84_21755	COG1129	ABC transporter
A6U84_21760	COG0842	Transport permease protein
A6U84_21775	COG0784	Response regulator, receiver
A6U84_21780	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A6U84_21790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_21795	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A6U84_21810	COG0765	amino acid transport
A6U84_21820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A6U84_21830	COG3938	Belongs to the proline racemase family
A6U84_21845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_21850	COG0765	amino acid transport
A6U84_21855	COG0765	amino acid transport
A6U84_21865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A6U84_21880	COG0402	S-adenosylhomocysteine deaminase activity
A6U84_21890	COG0601	transmembrane transport
A6U84_21895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_21905	COG0402	S-adenosylhomocysteine deaminase activity
A6U84_21910	COG0444	Belongs to the ABC transporter superfamily
A6U84_21915	COG4608	Belongs to the ABC transporter superfamily
A6U84_21920	COG1802	Transcriptional regulator
A6U84_21925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6U84_21950	COG3383	formate dehydrogenase (NAD+) activity
A6U84_21960	COG2223	nitrite transmembrane transporter activity
A6U84_21965	COG0456	acetyltransferase
A6U84_21995	COG3237	CsbD-like
A6U84_22000	COG2197	response regulator
A6U84_22005	COG3181	Tripartite tricarboxylate transporter family receptor
A6U84_22015	COG5265	(ABC) transporter
A6U84_22020	COG0640	Transcriptional regulator
A6U84_22035	COG0753	catalase activity
A6U84_22080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A6U84_22100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A6U84_22105	COG2203	Gaf domain
A6U84_22105	COG3706	GGDEF domain
A6U84_22105	COG4251	negative regulation of phosphorylation
A6U84_22105	COG5001	Diguanylate cyclase
A6U84_22120	COG3046	protein related to deoxyribodipyrimidine photolyase
A6U84_22165	COG1595	DNA-templated transcription, initiation
A6U84_22175	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_22180	COG1309	transcriptional regulator
A6U84_22200	COG1126	abc transporter atp-binding protein
A6U84_22205	COG0765	amino acid transport
A6U84_22210	COG0765	amino acid transport
A6U84_22215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_22220	COG3608	succinylglutamate desuccinylase aspartoacylase
A6U84_22225	COG0006	proline dipeptidase activity
A6U84_22230	COG2423	ornithine cyclodeaminase activity
A6U84_22235	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A6U84_22240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A6U84_22245	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
A6U84_22255	COG1522	sequence-specific DNA binding
A6U84_22495	COG0753	catalase activity
A6U84_22500	COG3685	Protein conserved in bacteria
A6U84_22535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
A6U84_22540	COG0297	glycogen (starch) synthase activity
A6U84_22610	COG4106	trans-aconitate 2-methyltransferase activity
A6U84_22630	COG2814	Major facilitator Superfamily
A6U84_22635	COG0583	DNA-binding transcription factor activity
A6U84_22640	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_22670	COG0406	alpha-ribazole phosphatase activity
A6U84_22695	COG3550	peptidyl-serine autophosphorylation
A6U84_22755	COG1192	Involved in chromosome partitioning
A6U84_22760	COG1475	DNA binding
A6U84_22765	COG0640	Transcriptional regulator
A6U84_22770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A6U84_22780	COG0583	DNA-binding transcription factor activity
A6U84_22800	COG3177	Filamentation induced by cAMP protein fic
A6U84_22815	COG3971	2-oxopent-4-enoate hydratase activity
A6U84_22820	COG3485	protocatechuate 3,4-dioxygenase
A6U84_22885	COG3727	T/G mismatch-specific endonuclease activity
A6U84_22910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A6U84_22930	COG2207	Transcriptional regulator
A6U84_22950	COG0559	Belongs to the binding-protein-dependent transport system permease family
A6U84_22965	COG1830	Aldolase
A6U84_22970	COG1802	Transcriptional regulator
A6U84_22980	COG1175	transmembrane transport
A6U84_22985	COG0395	ABC-type sugar transport system, permease component
A6U84_22990	COG1063	alcohol dehydrogenase
A6U84_22995	COG1070	Carbohydrate kinase
A6U84_23000	COG3842	ATPase activity
A6U84_23005	COG2376	Dihydroxyacetone kinase
A6U84_23015	COG3842	ATPase activity
A6U84_23020	COG1177	transmembrane transport
A6U84_23025	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_23040	COG1609	Transcriptional regulator
A6U84_23050	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A6U84_23055	COG3791	Glutathione-dependent formaldehyde-activating
A6U84_23060	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A6U84_23070	COG4993	Dehydrogenase
A6U84_23075	COG0583	DNA-binding transcription factor activity
A6U84_23080	COG2267	carboxylic ester hydrolase activity
A6U84_23085	COG1942	4-Oxalocrotonate Tautomerase
A6U84_23100	COG0604	alcohol dehydrogenase
A6U84_23110	COG1942	4-Oxalocrotonate Tautomerase
A6U84_23120	COG2211	Major facilitator Superfamily
A6U84_23125	COG1472	Belongs to the glycosyl hydrolase 3 family
A6U84_23130	COG4702	Belongs to the UPF0303 family
A6U84_23140	COG0823	Involved in the tonB-independent uptake of proteins
A6U84_23150	COG2353	YceI-like domain
A6U84_23210	COG1129	ABC transporter
A6U84_23250	COG3842	ATPase activity
A6U84_23255	COG0395	ABC-type sugar transport system, permease component
A6U84_23260	COG1175	transmembrane transport
A6U84_23270	COG1609	Transcriptional regulator
A6U84_23315	COG3485	protocatechuate 3,4-dioxygenase
A6U84_23320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A6U84_23345	COG2259	Doxx family
A6U84_23350	COG2514	catechol 2,3-dioxygenase activity
A6U84_23360	COG0435	Glutathione S-transferase
A6U84_23390	COG0431	NADPH-dependent FMN reductase
A6U84_23425	COG1942	4-Oxalocrotonate Tautomerase
A6U84_23430	COG0583	DNA-binding transcription factor activity
A6U84_23435	COG0583	DNA-binding transcription factor activity
A6U84_23445	COG0346	lactoylglutathione lyase activity
A6U84_23520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A6U84_23525	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_23535	COG0183	Belongs to the thiolase family
A6U84_23540	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6U84_23540	COG1024	Enoyl-CoA hydratase
A6U84_23545	COG0477	Major facilitator Superfamily
A6U84_23550	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
A6U84_23565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
A6U84_23570	COG1454	alcohol dehydrogenase
A6U84_23580	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_23585	COG0747	negative chemotaxis
A6U84_23590	COG0601	transmembrane transport
A6U84_23595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_23605	COG4172	Belongs to the ABC transporter superfamily
A6U84_23630	COG0745	RESPONSE REGULATOR receiver
A6U84_23635	COG5002	protein histidine kinase activity
A6U84_23655	COG2086	electron transfer activity
A6U84_23665	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6U84_23665	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6U84_23670	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
A6U84_23685	COG1063	alcohol dehydrogenase
A6U84_23690	COG0183	Belongs to the thiolase family
A6U84_23695	COG1024	Enoyl-CoA hydratase
A6U84_23695	COG1250	3-hydroxyacyl-CoA dehydrogenase
A6U84_23700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6U84_23705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_23710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A6U84_23720	COG3284	Transcriptional regulator
A6U84_23725	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_23730	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_23750	COG1129	ABC transporter
A6U84_23755	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_23760	COG1879	ABC-type sugar transport system periplasmic component
A6U84_23765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A6U84_23770	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
A6U84_23775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A6U84_23790	COG4221	oxidoreductase activity
A6U84_23795	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_23805	COG3620	sequence-specific DNA binding
A6U84_23810	COG3550	peptidyl-serine autophosphorylation
A6U84_23825	COG1609	Transcriptional regulator
A6U84_23850	COG0673	inositol 2-dehydrogenase activity
A6U84_23860	COG1802	Transcriptional regulator
A6U84_23900	COG0840	transmembrane signaling receptor activity
A6U84_23930	COG0587	DNA-directed DNA polymerase activity
A6U84_23950	COG5489	Protein of unknown function (DUF736)
A6U84_23960	COG0776	regulation of translation
A6U84_23965	COG3831	ATPase activity
A6U84_23970	COG3505	Type IV secretory pathway VirD4
A6U84_24005	COG0583	DNA-binding transcription factor activity
A6U84_24020	COG1285	pathogenesis
A6U84_24025	COG4372	Transposase
A6U84_24030	COG3436	PFAM IS66 Orf2 family protein
A6U84_24035	COG2963	transposase activity
A6U84_24065	COG0745	RESPONSE REGULATOR receiver
A6U84_24105	COG3842	ATPase activity
A6U84_24110	COG4208	sulfate ABC transporter
A6U84_24115	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_24120	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
A6U84_24135	COG0577	efflux transmembrane transporter activity
A6U84_24145	COG1414	Transcriptional regulator
A6U84_24155	COG1454	alcohol dehydrogenase
A6U84_24160	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A6U84_24170	COG4221	oxidoreductase activity
A6U84_24175	COG2186	Transcriptional regulator
A6U84_24185	COG0765	amino acid transport
A6U84_24195	COG3842	ATPase activity
A6U84_24210	COG1177	transmembrane transport
A6U84_24220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A6U84_24250	COG3436	PFAM IS66 Orf2 family protein
A6U84_24255	COG4372	Transposase
A6U84_24260	COG3012	SEC-C Motif Domain Protein
A6U84_24295	COG3838	Conjugal transfer protein Trbc
A6U84_24300	COG3702	type iv secretory pathway
A6U84_24305	COG3451	type IV secretory pathway VirB4
A6U84_24320	COG3704	protein secretion by the type IV secretion system
A6U84_24330	COG3736	Type IV secretory pathway, component VirB8
A6U84_24335	COG3504	Conjugal transfer protein
A6U84_24340	COG2948	multi-organism process
A6U84_24345	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
A6U84_24350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6U84_24355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A6U84_24365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A6U84_24385	COG0784	Response regulator, receiver
A6U84_24385	COG4191	Histidine kinase
A6U84_24400	COG4691	Plasmid stability protein
A6U84_24405	COG1487	ribonuclease activity
A6U84_24410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_24420	COG2186	Transcriptional regulator
A6U84_24425	COG0747	negative chemotaxis
A6U84_24430	COG0601	transmembrane transport
A6U84_24435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_24440	COG4172	Belongs to the ABC transporter superfamily
A6U84_24445	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_24485	COG1595	DNA-templated transcription, initiation
A6U84_24500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
A6U84_24510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_24515	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A6U84_24520	COG1120	ATPase activity
A6U84_24530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
A6U84_24535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
A6U84_24550	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A6U84_24585	COG1176	ABC-type spermidine putrescine transport system, permease component I
A6U84_24590	COG3842	ATPase activity
A6U84_24595	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_24600	COG0628	permease
A6U84_24620	COG3734	2-keto-3-deoxy-galactonokinase
A6U84_24625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A6U84_24630	COG4948	Mandelate Racemase Muconate Lactonizing
A6U84_24640	COG1175	transmembrane transport
A6U84_24645	COG0395	ABC-type sugar transport system, permease component
A6U84_24650	COG3842	ATPase activity
A6U84_24660	COG1414	Transcriptional regulator
A6U84_24665	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_24670	COG2207	Transcriptional regulator
A6U84_24680	COG0583	DNA-binding transcription factor activity
A6U84_24685	COG0667	Aldo Keto reductase
A6U84_24690	COG0583	DNA-binding transcription factor activity
A6U84_24695	COG0604	alcohol dehydrogenase
A6U84_24705	COG1609	Transcriptional regulator
A6U84_24710	COG1082	Xylose isomerase domain protein TIM barrel
A6U84_24715	COG0673	inositol 2-dehydrogenase activity
A6U84_24720	COG1082	Xylose isomerase domain protein TIM barrel
A6U84_24730	COG0405	Gamma-glutamyltransferase
A6U84_24740	COG1215	transferase activity, transferring glycosyl groups
A6U84_24760	COG4753	response regulator
A6U84_24760	COG2207	Transcriptional regulator
A6U84_24785	COG0840	transmembrane signaling receptor activity
A6U84_24795	COG0156	8-amino-7-oxononanoate synthase activity
A6U84_24800	COG2197	response regulator
A6U84_24815	COG2390	Transcriptional regulator
A6U84_24820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A6U84_24825	COG3958	Transketolase
A6U84_24830	COG3959	Transketolase, thiamine diphosphate binding domain
A6U84_24835	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_24845	COG1129	ABC transporter
A6U84_24850	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_24855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A6U84_24885	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_24905	COG0583	DNA-binding transcription factor activity
A6U84_24920	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A6U84_24925	COG1741	Belongs to the pirin family
A6U84_24930	COG1335	isochorismatase
A6U84_24935	COG0583	DNA-binding transcription factor activity
A6U84_24940	COG1733	regulation of RNA biosynthetic process
A6U84_24945	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_24945	COG0604	alcohol dehydrogenase
A6U84_24945	COG3321	synthase
A6U84_24950	COG0583	DNA-binding transcription factor activity
A6U84_24970	COG1017	nitric oxide dioxygenase activity
A6U84_24970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A6U84_24975	COG0625	glutathione transferase activity
A6U84_24985	COG0583	DNA-binding transcription factor activity
A6U84_25010	COG1349	DNA-binding transcription factor activity
A6U84_25015	COG1879	ABC-type sugar transport system periplasmic component
A6U84_25020	COG1129	ABC transporter
A6U84_25025	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_25030	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_25050	COG1012	belongs to the aldehyde dehydrogenase family
A6U84_25055	COG1280	lysine exporter protein (LysE YggA)
A6U84_25060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A6U84_25100	COG4302	ethanolamine ammonia-lyase activity
A6U84_25105	COG4303	Ethanolamine ammonia lyase large subunit
A6U84_25125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A6U84_25130	COG1349	DNA-binding transcription factor activity
A6U84_25135	COG4608	Belongs to the ABC transporter superfamily
A6U84_25145	COG0601	transmembrane transport
A6U84_25150	COG0747	negative chemotaxis
A6U84_25160	COG3842	ATPase activity
A6U84_25165	COG1063	alcohol dehydrogenase
A6U84_25170	COG0395	ABC-type sugar transport system, permease component
A6U84_25175	COG1175	transmembrane transport
A6U84_25180	COG1653	transport
A6U84_25210	COG0326	Molecular chaperone. Has ATPase activity
A6U84_25220	COG1881	PFAM PEBP family protein
A6U84_25230	COG1132	(ABC) transporter
A6U84_25260	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A6U84_25265	COG0071	Belongs to the small heat shock protein (HSP20) family
A6U84_25275	COG2217	Heavy metal translocating P-type atpase
A6U84_25280	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
A6U84_25285	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A6U84_25300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A6U84_25305	COG0784	Response regulator, receiver
A6U84_25305	COG4191	Histidine kinase
A6U84_25325	COG2826	transposase and inactivated derivatives, IS30 family
A6U84_25340	COG1028	Short-chain dehydrogenase reductase Sdr
A6U84_25360	COG0436	Aminotransferase
A6U84_25375	COG1079	Belongs to the binding-protein-dependent transport system permease family
A6U84_25405	COG0778	Nitroreductase
A6U84_25410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A6U84_25425	COG0559	Belongs to the binding-protein-dependent transport system permease family
A6U84_25450	COG0583	DNA-binding transcription factor activity
A6U84_25455	COG0667	Aldo Keto reductase
A6U84_25475	COG1278	Cold shock
A6U84_25485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A6U84_25490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A6U84_25515	COG1538	Outer membrane efflux protein
A6U84_25535	COG1126	abc transporter atp-binding protein
A6U84_25545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A6U84_25550	COG1609	Transcriptional regulator
A6U84_25555	COG1192	Involved in chromosome partitioning
A6U84_25560	COG1475	DNA binding
A6U84_25565	COG0640	Transcriptional regulator
A6U84_25610	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
A6U84_25655	COG3838	Conjugal transfer protein Trbc
A6U84_25665	COG3451	type IV secretory pathway VirB4
A6U84_25670	COG0741	lytic transglycosylase activity
A6U84_25795	COG1475	DNA binding
A6U84_25800	COG1396	sequence-specific DNA binding
A6U84_25825	COG4423	Transcription factor
A6U84_25900	COG3772	lysozyme
A6U84_25925	COG1192	Involved in chromosome partitioning
A6U84_25930	COG1475	DNA binding
A6U84_25935	COG0640	Transcriptional regulator
A6U84_25940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A6U84_25970	COG2211	Major facilitator Superfamily
A6U84_26020	COG1051	belongs to the nudix hydrolase family
A6U84_26065	COG1475	DNA binding
A6U84_26090	COG2824	Alkylphosphonate utilization operon protein PhnA
A6U84_26110	COG4974	Belongs to the 'phage' integrase family
A6U84_26115	COG0582	viral genome integration into host DNA
A6U84_26120	COG4974	Belongs to the 'phage' integrase family
A6U84_26140	COG1172	Belongs to the binding-protein-dependent transport system permease family
A6U84_26145	COG1879	ABC-type sugar transport system periplasmic component
A6U84_26185	COG5489	Protein of unknown function (DUF736)
A6U84_26270	COG1283	sodium-dependent phosphate transmembrane transporter activity
A6U84_26285	COG0747	negative chemotaxis
A6U84_26305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A6U84_26310	COG0584	glycerophosphoryl diester phosphodiesterase
A6U84_26315	COG0483	inositol monophosphate 1-phosphatase activity
A6U84_26380	COG3161	chorismate lyase activity
A6U84_26655	COG0145	ligase activity
A6U84_26665	COG0583	DNA-binding transcription factor activity
A6U84_26710	COG3701	Conjugal transfer protein
A6U84_26715	COG3846	protein secretion by the type IV secretion system
A6U84_26725	COG5314	conjugation
A6U84_26730	COG3451	type IV secretory pathway VirB4
A6U84_26745	COG4962	Type ii secretion system protein e