locus-tag	class	description
EYD00_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYD00_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYD00_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EYD00_00025	COG1420	regulation of RNA biosynthetic process
EYD00_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYD00_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYD00_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EYD00_00050	COG1137	ATPase activity
EYD00_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EYD00_00065	COG0616	signal peptide processing
EYD00_00070	COG0776	regulation of translation
EYD00_00080	COG0116	Belongs to the methyltransferase superfamily
EYD00_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYD00_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYD00_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYD00_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYD00_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EYD00_00115	COG0728	peptidoglycan biosynthetic process
EYD00_00125	COG0180	Tryptophanyl-tRNA synthetase
EYD00_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EYD00_00140	COG1214	PFAM Peptidase M22, glycoprotease
EYD00_00145	COG0456	acetyltransferase
EYD00_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYD00_00165	COG1702	phosphate starvation-inducible protein PhoH
EYD00_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYD00_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EYD00_00185	COG1396	sequence-specific DNA binding
EYD00_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYD00_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYD00_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_00210	COG0242	peptide deformylase activity
EYD00_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EYD00_00220	COG0101	tRNA pseudouridine synthase activity
EYD00_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYD00_00235	COG2171	N-acyltransferase activity
EYD00_00245	COG0840	transmembrane signaling receptor activity
EYD00_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
EYD00_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYD00_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYD00_00295	COG0706	membrane insertase activity
EYD00_00300	COG0594	ribonuclease P activity
EYD00_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EYD00_00310	COG0840	transmembrane signaling receptor activity
EYD00_00325	COG2226	methyltransferase
EYD00_00330	COG3842	ATPase activity
EYD00_00335	COG1175	transmembrane transport
EYD00_00340	COG0395	ABC-type sugar transport system, permease component
EYD00_00355	COG0427	acetyl-CoA hydrolase
EYD00_00365	COG3938	Belongs to the proline racemase family
EYD00_00370	COG0418	dihydroorotase activity
EYD00_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYD00_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYD00_00400	COG0166	Belongs to the GPI family
EYD00_00405	COG0318	PFAM AMP-dependent synthetase and ligase
EYD00_00410	COG3842	ATPase activity
EYD00_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
EYD00_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYD00_00425	COG4774	siderophore transport
EYD00_00465	COG2326	polyphosphate kinase activity
EYD00_00470	COG5002	protein histidine kinase activity
EYD00_00475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EYD00_00480	COG0573	inorganic phosphate transmembrane transporter activity
EYD00_00490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYD00_00495	COG0704	Plays a role in the regulation of phosphate uptake
EYD00_00500	COG0745	RESPONSE REGULATOR receiver
EYD00_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYD00_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYD00_00525	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYD00_00530	COG2967	ApaG domain
EYD00_00540	COG0717	Belongs to the dCTP deaminase family
EYD00_00550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EYD00_00580	COG0726	polysaccharide deacetylase
EYD00_00600	COG0167	dihydroorotate dehydrogenase activity
EYD00_00615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYD00_00635	COG1959	2 iron, 2 sulfur cluster binding
EYD00_00640	COG1201	RNA secondary structure unwinding
EYD00_00675	COG1960	acyl-CoA dehydrogenase activity
EYD00_00680	COG0183	Belongs to the thiolase family
EYD00_00685	COG1024	Enoyl-CoA hydratase
EYD00_00685	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYD00_00705	COG1320	monovalent cation:proton antiporter activity
EYD00_00710	COG2212	antiporter activity
EYD00_00715	COG1863	multisubunit Na H antiporter MnhE subunit
EYD00_00720	COG0651	ATP synthesis coupled electron transport
EYD00_00725	COG1006	Multisubunit Na H antiporter MnhC subunit
EYD00_00730	COG2111	Na H antiporter
EYD00_00730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EYD00_00740	COG0840	transmembrane signaling receptor activity
EYD00_00755	COG0643	Histidine kinase
EYD00_00755	COG2198	Histidine kinase
EYD00_00760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EYD00_00765	COG2201	protein-glutamate methylesterase activity
EYD00_00770	COG0745	RESPONSE REGULATOR receiver
EYD00_00775	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EYD00_00785	COG1766	The M ring may be actively involved in energy transduction
EYD00_00790	COG2771	luxR family
EYD00_00800	COG0840	transmembrane signaling receptor activity
EYD00_00800	COG2972	Histidine kinase
EYD00_00805	COG2198	Histidine kinase
EYD00_00805	COG2205	protein histidine kinase activity
EYD00_00805	COG0784	Response regulator, receiver
EYD00_00810	COG1970	mechanosensitive ion channel activity
EYD00_00815	COG0436	Aminotransferase
EYD00_00830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EYD00_00835	COG0424	maF-like protein
EYD00_00840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYD00_00850	COG5328	Belongs to the UPF0262 family
EYD00_00855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYD00_00865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYD00_00930	COG4974	Belongs to the 'phage' integrase family
EYD00_00935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYD00_00955	COG1338	Plays a role in the flagellum-specific transport system
EYD00_00965	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EYD00_00975	COG1706	bacterial-type flagellum-dependent cell motility
EYD00_00980	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EYD00_00985	COG4786	Flagellar basal body rod
EYD00_00990	COG1677	Flagellar hook-basal body complex protein FliE
EYD00_00995	COG1558	bacterial-type flagellum-dependent cell motility
EYD00_01000	COG1815	bacterial-type flagellum-dependent cell motility
EYD00_01010	COG1157	protein secretion by the type III secretion system
EYD00_01015	COG4786	Flagellar basal body rod
EYD00_01025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EYD00_01030	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYD00_01035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYD00_01040	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EYD00_01045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYD00_01060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EYD00_01070	COG1360	Flagellar Motor Protein
EYD00_01095	COG1749	Flagellar hook protein flgE
EYD00_01115	COG5443	negative regulation of bacterial-type flagellum assembly
EYD00_01120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EYD00_01130	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EYD00_01170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYD00_01175	COG1609	Transcriptional regulator
EYD00_01180	COG1653	transport
EYD00_01185	COG1175	transmembrane transport
EYD00_01190	COG0395	ABC-type sugar transport system, permease component
EYD00_01195	COG0366	Alpha amylase catalytic
EYD00_01200	COG3842	ATPase activity
EYD00_01215	COG0129	dihydroxy-acid dehydratase activity
EYD00_01220	COG0363	glucosamine-6-phosphate deaminase activity
EYD00_01225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EYD00_01230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_01240	COG2081	HI0933 family
EYD00_01265	COG2224	Isocitrate lyase
EYD00_01280	COG3842	ATPase activity
EYD00_01285	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYD00_01290	COG1177	transmembrane transport
EYD00_01300	COG2205	protein histidine kinase activity
EYD00_01310	COG0248	Ppx GppA phosphatase
EYD00_01315	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EYD00_01320	COG0477	Major facilitator Superfamily
EYD00_01355	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYD00_01360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EYD00_01370	COG0142	geranyltranstransferase activity
EYD00_01380	COG0357	Ribosomal RNA small subunit methyltransferase G
EYD00_01395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYD00_01400	COG0752	glycyl-tRNA synthetase alpha subunit
EYD00_01410	COG1704	LemA family
EYD00_01415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EYD00_01425	COG0751	glycine-tRNA ligase activity
EYD00_01435	COG1683	Conserved Protein
EYD00_01440	COG0840	transmembrane signaling receptor activity
EYD00_01450	COG0151	Belongs to the GarS family
EYD00_01455	COG2183	response to ionizing radiation
EYD00_01460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYD00_01470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EYD00_01485	COG0583	DNA-binding transcription factor activity
EYD00_01505	COG0306	phosphate transporter
EYD00_01520	COG0561	phosphatase activity
EYD00_01525	COG0438	transferase activity, transferring glycosyl groups
EYD00_01530	COG2186	Transcriptional regulator
EYD00_01540	COG0583	DNA-binding transcription factor activity
EYD00_01545	COG0277	FAD linked oxidase domain protein
EYD00_01555	COG0277	FAD linked oxidase domain protein
EYD00_01560	COG0247	lactate metabolic process
EYD00_01570	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_01575	COG2818	Glycosylase
EYD00_01585	COG2855	membrane
EYD00_01590	COG0583	DNA-binding transcription factor activity
EYD00_01620	COG0124	histidyl-tRNA synthetase
EYD00_01630	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EYD00_01635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYD00_01640	COG2259	Doxx family
EYD00_01650	COG0459	protein refolding
EYD00_01655	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYD00_01665	COG0196	riboflavin kinase activity
EYD00_01670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYD00_01680	COG0590	tRNA wobble adenosine to inosine editing
EYD00_01685	COG1187	pseudouridine synthase activity
EYD00_01690	COG0742	ribosomal rna small subunit methyltransferase
EYD00_01695	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYD00_01700	COG0475	glutathione-regulated potassium exporter activity
EYD00_01700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYD00_01705	COG0312	modulator of DNA gyrase
EYD00_01710	COG0483	inositol monophosphate 1-phosphatase activity
EYD00_01720	COG1519	Transferase
EYD00_01730	COG1663	tetraacyldisaccharide 4'-kinase activity
EYD00_01740	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EYD00_01750	COG5001	Diguanylate cyclase
EYD00_01750	COG3300	MHYT domain
EYD00_01760	COG3386	PFAM SMP-30 Gluconolaconase
EYD00_01765	COG0800	Aldolase
EYD00_01770	COG3734	2-keto-3-deoxy-galactonokinase
EYD00_01775	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_01780	COG1414	Transcriptional regulator
EYD00_01785	COG2197	response regulator
EYD00_01790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_01800	COG0598	Magnesium transport protein CorA
EYD00_01805	COG3158	transport of potassium into the cell
EYD00_01820	COG0356	it plays a direct role in the translocation of protons across the membrane
EYD00_01830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYD00_01835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYD00_01840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYD00_01845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYD00_01865	COG0009	L-threonylcarbamoyladenylate synthase
EYD00_01875	COG4638	Rieske (2fe-2S)
EYD00_01900	COG1960	acyl-CoA dehydrogenase activity
EYD00_01915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYD00_01925	COG0840	transmembrane signaling receptor activity
EYD00_01935	COG1522	sequence-specific DNA binding
EYD00_01960	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYD00_01965	COG1741	Belongs to the pirin family
EYD00_01970	COG1722	exodeoxyribonuclease VII activity
EYD00_01975	COG0123	including yeast histone deacetylase and acetoin utilization protein
EYD00_01980	COG1268	BioY protein
EYD00_01985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYD00_01990	COG1122	ATPase activity
EYD00_01995	COG3214	Protein conserved in bacteria
EYD00_02005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EYD00_02020	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EYD00_02035	COG0259	pyridoxamine-phosphate oxidase activity
EYD00_02050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYD00_02060	COG0312	modulator of DNA gyrase
EYD00_02075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYD00_02080	COG0109	protoheme IX farnesyltransferase activity
EYD00_02090	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EYD00_02105	COG3346	SURF1 family
EYD00_02110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYD00_02115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EYD00_02120	COG0328	RNA-DNA hybrid ribonuclease activity
EYD00_02130	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EYD00_02130	COG0678	peroxiredoxin activity
EYD00_02140	COG1678	Uncharacterized ACR, COG1678
EYD00_02155	COG3300	MHYT domain
EYD00_02155	COG5001	Diguanylate cyclase
EYD00_02160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYD00_02165	COG0612	Peptidase, M16
EYD00_02185	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYD00_02190	COG1802	Transcriptional regulator
EYD00_02210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EYD00_02215	COG3609	addiction module antidote protein, CC2985 family
EYD00_02230	COG1194	a g-specific adenine glycosylase
EYD00_02245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EYD00_02250	COG1196	nuclear chromosome segregation
EYD00_02255	COG2514	catechol 2,3-dioxygenase activity
EYD00_02260	COG0574	Belongs to the PEP-utilizing enzyme family
EYD00_02260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYD00_02310	COG0579	oxidoreductase
EYD00_02330	COG2895	sulfate adenylyltransferase (ATP) activity
EYD00_02335	COG0175	sulfate reduction
EYD00_02340	COG0175	sulfate reduction
EYD00_02345	COG1959	2 iron, 2 sulfur cluster binding
EYD00_02350	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYD00_02355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EYD00_02360	COG4208	sulfate ABC transporter
EYD00_02365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYD00_02385	COG2199	diguanylate cyclase activity
EYD00_02385	COG2200	EAL domain
EYD00_02385	COG2203	Gaf domain
EYD00_02395	COG1309	transcriptional regulator
EYD00_02400	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_02410	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
EYD00_02445	COG0625	glutathione transferase activity
EYD00_02455	COG0477	Major facilitator Superfamily
EYD00_02475	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYD00_02475	COG1793	dna ligase
EYD00_02495	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_02500	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_02505	COG1846	Transcriptional regulator
EYD00_02510	COG1764	response to oxidative stress
EYD00_02525	COG0488	(ABC) transporter
EYD00_02565	COG4221	oxidoreductase activity
EYD00_02580	COG0433	COG0433 Predicted ATPase
EYD00_02590	COG1733	regulation of RNA biosynthetic process
EYD00_02595	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EYD00_02605	COG1280	lysine exporter protein (LysE YggA)
EYD00_02610	COG0656	L-ascorbic acid biosynthetic process
EYD00_02615	COG3781	membrane
EYD00_02620	COG2378	regulation of single-species biofilm formation
EYD00_02635	COG4106	trans-aconitate 2-methyltransferase activity
EYD00_02640	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYD00_02645	COG0840	transmembrane signaling receptor activity
EYD00_02650	COG0583	DNA-binding transcription factor activity
EYD00_02665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYD00_02685	COG3909	cytochrome
EYD00_02690	COG2010	Cytochrome c
EYD00_02725	COG0789	Transcriptional regulator
EYD00_02755	COG0517	IMP dehydrogenase activity
EYD00_02755	COG4175	Glycine betaine
EYD00_02760	COG4176	ABC-type proline glycine betaine transport system permease component
EYD00_02790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_02800	COG2169	Transcriptional regulator
EYD00_02800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYD00_02810	COG2514	catechol 2,3-dioxygenase activity
EYD00_02825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYD00_02830	COG1272	protein, Hemolysin III
EYD00_02840	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYD00_02850	COG2111	Na H antiporter
EYD00_02855	COG1006	Multisubunit Na H antiporter MnhC subunit
EYD00_02865	COG1863	multisubunit Na H antiporter MnhE subunit
EYD00_02870	COG2212	antiporter activity
EYD00_02875	COG1320	monovalent cation:proton antiporter activity
EYD00_02895	COG2166	iron-sulfur cluster assembly
EYD00_02905	COG2205	protein histidine kinase activity
EYD00_02965	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYD00_02970	COG2983	Belongs to the UPF0260 family
EYD00_03025	COG1621	beta-fructofuranosidase activity
EYD00_03030	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EYD00_03080	COG4695	Portal protein
EYD00_03170	COG0745	RESPONSE REGULATOR receiver
EYD00_03175	COG2205	protein histidine kinase activity
EYD00_03185	COG4235	cytochrome complex assembly
EYD00_03190	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EYD00_03195	COG1138	Cytochrome C-type biogenesis protein
EYD00_03200	COG3088	subunit of a heme lyase
EYD00_03205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYD00_03210	COG0745	RESPONSE REGULATOR receiver
EYD00_03215	COG2205	protein histidine kinase activity
EYD00_03225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EYD00_03230	COG2205	protein histidine kinase activity
EYD00_03230	COG2202	Pas domain
EYD00_03240	COG0308	aminopeptidase N
EYD00_03245	COG0697	spore germination
EYD00_03265	COG0443	Heat shock 70 kDa protein
EYD00_03270	COG5002	protein histidine kinase activity
EYD00_03270	COG5001	Diguanylate cyclase
EYD00_03270	COG3447	MASE1 domain protein
EYD00_03275	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_03300	COG0604	alcohol dehydrogenase
EYD00_03305	COG1733	regulation of RNA biosynthetic process
EYD00_03310	COG1968	undecaprenyl-diphosphatase activity
EYD00_03315	COG2239	Acts as a magnesium transporter
EYD00_03320	COG2814	Major facilitator Superfamily
EYD00_03350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYD00_03375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYD00_03425	COG0741	lytic transglycosylase activity
EYD00_03435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_03440	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYD00_03445	COG0840	transmembrane signaling receptor activity
EYD00_03455	COG1758	RNA polymerase activity
EYD00_03480	COG0736	holo-[acyl-carrier-protein] synthase activity
EYD00_03485	COG0681	Belongs to the peptidase S26 family
EYD00_03490	COG0571	ribonuclease III activity
EYD00_03495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYD00_03500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYD00_03505	COG0784	Response regulator, receiver
EYD00_03510	COG1381	Involved in DNA repair and RecF pathway recombination
EYD00_03520	COG2226	methyltransferase
EYD00_03535	COG1418	mRNA catabolic process
EYD00_03545	COG0346	lactoylglutathione lyase activity
EYD00_03555	COG1116	anion transmembrane transporter activity
EYD00_03560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_03565	COG3443	Belongs to the bacterial solute-binding protein 9 family
EYD00_03570	COG0668	transmembrane transport
EYD00_03580	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EYD00_03610	COG1742	UPF0060 membrane protein
EYD00_03620	COG0745	RESPONSE REGULATOR receiver
EYD00_03620	COG3706	GGDEF domain
EYD00_03625	COG1183	phosphatidylcholine synthase activity
EYD00_03630	COG0688	phosphatidylethanolamine metabolic process
EYD00_03635	COG5265	(ABC) transporter
EYD00_03675	COG2852	Protein conserved in bacteria
EYD00_03680	COG0215	cysteine-tRNA ligase activity
EYD00_03685	COG4221	oxidoreductase activity
EYD00_03690	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYD00_03695	COG1286	toxin biosynthetic process
EYD00_03715	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYD00_03725	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EYD00_03735	COG0305	Participates in initiation and elongation during chromosome replication
EYD00_03755	COG0359	binds to the 23S rRNA
EYD00_03765	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYD00_03770	COG0360	Binds together with S18 to 16S ribosomal RNA
EYD00_03780	COG0667	Aldo Keto reductase
EYD00_03785	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYD00_03795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYD00_03800	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYD00_03805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EYD00_03810	COG1561	YicC-like family, N-terminal region
EYD00_03815	COG0194	GDP metabolic process
EYD00_03820	COG0400	carboxylic ester hydrolase activity
EYD00_03825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYD00_03830	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYD00_03840	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EYD00_03855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYD00_03875	COG3706	GGDEF domain
EYD00_03875	COG4251	negative regulation of phosphorylation
EYD00_03875	COG2203	Gaf domain
EYD00_03875	COG5001	Diguanylate cyclase
EYD00_03880	COG5001	Diguanylate cyclase
EYD00_03880	COG3300	MHYT domain
EYD00_03885	COG4191	Histidine kinase
EYD00_03900	COG0488	(ABC) transporter
EYD00_03905	COG3706	GGDEF domain
EYD00_03915	COG0105	UTP biosynthetic process
EYD00_03935	COG0314	molybdopterin synthase activity
EYD00_03945	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYD00_03950	COG0322	excinuclease ABC activity
EYD00_03955	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_03965	COG0625	glutathione transferase activity
EYD00_03980	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EYD00_03985	COG0243	molybdopterin cofactor binding
EYD00_04010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYD00_04015	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYD00_04020	COG0628	permease
EYD00_04030	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYD00_04035	COG0248	Ppx GppA phosphatase
EYD00_04060	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EYD00_04065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EYD00_04070	COG0477	Major facilitator Superfamily
EYD00_04075	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYD00_04085	COG4452	Inner membrane protein CreD
EYD00_04095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYD00_04100	COG3654	unkown
EYD00_04110	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EYD00_04120	COG0113	porphobilinogen synthase activity
EYD00_04140	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EYD00_04145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYD00_04150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYD00_04150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EYD00_04160	COG1280	lysine exporter protein (LysE YggA)
EYD00_04165	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EYD00_04170	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYD00_04175	COG2814	Major facilitator Superfamily
EYD00_04180	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
EYD00_04200	COG0416	fatty acid biosynthetic process
EYD00_04205	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYD00_04210	COG0776	regulation of translation
EYD00_04245	COG0601	transmembrane transport
EYD00_04250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_04255	COG0444	Belongs to the ABC transporter superfamily
EYD00_04265	COG0747	negative chemotaxis
EYD00_04275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYD00_04280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYD00_04290	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EYD00_04295	COG0583	DNA-binding transcription factor activity
EYD00_04330	COG2897	thiosulfate sulfurtransferase activity
EYD00_04345	COG0415	Belongs to the DNA photolyase family
EYD00_04355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYD00_04390	COG3932	Exopolysaccharide synthesis, ExoD
EYD00_04395	COG1238	metal cluster binding
EYD00_04445	COG0297	glycogen (starch) synthase activity
EYD00_04470	COG1612	heme a metabolic process
EYD00_04480	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYD00_04485	COG0010	Belongs to the arginase family
EYD00_04490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYD00_04495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EYD00_04505	COG1832	CoA-binding protein
EYD00_04525	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_04530	COG2124	cytochrome p450
EYD00_04540	COG0740	serine-type endopeptidase activity
EYD00_04545	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYD00_04555	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYD00_04565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYD00_04585	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYD00_04590	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYD00_04595	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYD00_04605	COG0649	NAD binding
EYD00_04615	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EYD00_04620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EYD00_04630	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EYD00_04635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EYD00_04645	COG0713	ATP synthesis coupled electron transport
EYD00_04660	COG1007	ATP synthesis coupled electron transport
EYD00_04665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYD00_04665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYD00_04685	COG0442	prolyl-tRNA aminoacylation
EYD00_04695	COG1136	(ABC) transporter
EYD00_04705	COG0587	DNA-directed DNA polymerase activity
EYD00_04715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYD00_04725	COG0784	Response regulator, receiver
EYD00_04730	COG3706	GGDEF domain
EYD00_04730	COG0745	RESPONSE REGULATOR receiver
EYD00_04735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYD00_04740	COG0477	Major facilitator Superfamily
EYD00_04755	COG0557	exoribonuclease II activity
EYD00_04760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYD00_04770	COG0758	DNA mediated transformation
EYD00_04775	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EYD00_04780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EYD00_04785	COG0540	Belongs to the ATCase OTCase family
EYD00_04790	COG1960	acyl-CoA dehydrogenase activity
EYD00_04795	COG0456	acetyltransferase
EYD00_04810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EYD00_04815	COG2824	Alkylphosphonate utilization operon protein PhnA
EYD00_04820	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EYD00_04825	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYD00_04830	COG0154	amidase activity
EYD00_04835	COG0456	acetyltransferase
EYD00_04840	COG3811	Belongs to the UPF0386 family
EYD00_04855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYD00_04865	COG0456	acetyltransferase
EYD00_04880	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EYD00_04885	COG0439	Biotin carboxylase
EYD00_04890	COG0511	ligase activity, forming carbon-carbon bonds
EYD00_04895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYD00_04905	COG0436	Aminotransferase
EYD00_04925	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_04930	COG1530	ribonuclease E activity
EYD00_04945	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYD00_04965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYD00_04970	COG0384	phenazine biosynthesis protein PhzF
EYD00_04985	COG0633	Ferredoxin
EYD00_04995	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYD00_05000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYD00_05005	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYD00_05015	COG3768	UPF0283 membrane protein
EYD00_05020	COG3106	COG3106 Predicted ATPase
EYD00_05030	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EYD00_05050	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYD00_05075	COG0583	DNA-binding transcription factor activity
EYD00_05085	COG0537	adenosine 5'-monophosphoramidase activity
EYD00_05110	COG0052	Belongs to the universal ribosomal protein uS2 family
EYD00_05115	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYD00_05120	COG0528	UMP kinase activity
EYD00_05125	COG0233	cytoplasmic translational termination
EYD00_05130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EYD00_05135	COG0575	Belongs to the CDS family
EYD00_05140	COG0750	zinc metalloprotease
EYD00_05145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYD00_05150	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYD00_05155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYD00_05160	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYD00_05165	COG3494	Protein of unknown function (DUF1009)
EYD00_05170	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EYD00_05175	COG0372	Belongs to the citrate synthase family
EYD00_05190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYD00_05225	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EYD00_05230	COG0148	phosphopyruvate hydratase activity
EYD00_05240	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EYD00_05245	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYD00_05245	COG0022	dehydrogenase e1 component
EYD00_05250	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYD00_05260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYD00_05270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EYD00_05275	COG0697	spore germination
EYD00_05295	COG2867	negative regulation of translational initiation
EYD00_05305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYD00_05305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYD00_05315	COG3852	Histidine kinase
EYD00_05320	COG2204	response regulator
EYD00_05325	COG5000	phosphorelay sensor kinase activity
EYD00_05330	COG2204	response regulator
EYD00_05335	COG0569	domain protein
EYD00_05340	COG1923	regulation of RNA biosynthetic process
EYD00_05345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYD00_05380	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EYD00_05390	COG0667	Aldo Keto reductase
EYD00_05405	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EYD00_05410	COG1121	(ABC) transporter
EYD00_05415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYD00_05430	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYD00_05435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYD00_05445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EYD00_05450	COG0629	single-stranded DNA binding
EYD00_05460	COG2239	Acts as a magnesium transporter
EYD00_05465	COG2095	MarC family integral membrane protein
EYD00_05470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYD00_05545	COG1802	Transcriptional regulator
EYD00_05545	COG4626	Terminase
EYD00_05590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYD00_05600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYD00_05605	COG0084	hydrolase, TatD family'
EYD00_05610	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYD00_05610	COG0321	lipoyl(octanoyl) transferase activity
EYD00_05620	COG2801	Transposase and inactivated derivatives
EYD00_05640	COG0625	glutathione transferase activity
EYD00_05645	COG0450	alkyl hydroperoxide reductase
EYD00_05655	COG1671	Belongs to the UPF0178 family
EYD00_05665	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EYD00_05670	COG0251	oxidation-reduction process
EYD00_05695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EYD00_05720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYD00_05725	COG0509	glycine decarboxylation via glycine cleavage system
EYD00_05730	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYD00_05730	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EYD00_05735	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EYD00_05775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYD00_05775	COG1648	precorrin-2 dehydrogenase activity
EYD00_05790	COG3956	TIGRFAM MazG family protein
EYD00_05835	COG2239	Acts as a magnesium transporter
EYD00_05840	COG0243	molybdopterin cofactor binding
EYD00_05850	COG0242	peptide deformylase activity
EYD00_05865	COG2205	protein histidine kinase activity
EYD00_05865	COG2202	Pas domain
EYD00_05875	COG0321	lipoyl(octanoyl) transferase activity
EYD00_05880	COG1064	alcohol dehydrogenase
EYD00_05930	COG2124	cytochrome p450
EYD00_05945	COG2267	carboxylic ester hydrolase activity
EYD00_05955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYD00_05960	COG0626	cystathionine gamma-synthase activity
EYD00_05965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_05970	COG4597	amino acid ABC transporter
EYD00_05975	COG0765	amino acid transport
EYD00_05980	COG1126	abc transporter atp-binding protein
EYD00_06010	COG0436	Aminotransferase
EYD00_06040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYD00_06050	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYD00_06055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYD00_06060	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYD00_06075	COG3243	poly(R)-hydroxyalkanoic acid synthase
EYD00_06085	COG1489	DNA binding
EYD00_06090	COG0024	Methionine aminopeptidase
EYD00_06095	COG2003	Belongs to the UPF0758 family
EYD00_06110	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EYD00_06135	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EYD00_06140	COG0546	phosphoglycolate phosphatase activity
EYD00_06160	COG0114	fumarate hydratase activity
EYD00_06165	COG0504	CTP synthase activity
EYD00_06175	COG0149	triose-phosphate isomerase activity
EYD00_06185	COG0187	DNA topoisomerase II activity
EYD00_06190	COG0740	serine-type endopeptidase activity
EYD00_06200	COG0640	Transcriptional regulator
EYD00_06205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYD00_06220	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EYD00_06220	COG3264	Mechanosensitive ion channel
EYD00_06280	COG1127	ABC transporter
EYD00_06285	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EYD00_06290	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_06300	COG0280	phosphate acetyltransferase
EYD00_06300	COG0281	malic enzyme
EYD00_06305	COG0346	lactoylglutathione lyase activity
EYD00_06315	COG0778	Nitroreductase
EYD00_06320	COG0823	Involved in the tonB-independent uptake of proteins
EYD00_06335	COG1368	sulfuric ester hydrolase activity
EYD00_06365	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYD00_06390	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EYD00_06410	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EYD00_06435	COG0512	Glutamine amidotransferase of anthranilate synthase
EYD00_06435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYD00_06440	COG0343	queuine tRNA-ribosyltransferase activity
EYD00_06445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYD00_06450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYD00_06455	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYD00_06460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYD00_06485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYD00_06490	COG0134	indole-3-glycerol-phosphate synthase activity
EYD00_06495	COG0315	cyclic pyranopterin monophosphate synthase activity
EYD00_06500	COG0303	'Molybdopterin
EYD00_06505	COG3706	GGDEF domain
EYD00_06515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EYD00_06515	COG0475	glutathione-regulated potassium exporter activity
EYD00_06525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYD00_06530	COG0697	spore germination
EYD00_06535	COG2814	Major facilitator Superfamily
EYD00_06540	COG0746	molybdenum cofactor guanylyltransferase activity
EYD00_06545	COG1763	Mo-molybdopterin cofactor biosynthetic process
EYD00_06550	COG0739	heme binding
EYD00_06555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYD00_06560	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EYD00_06565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYD00_06570	COG0805	protein transport
EYD00_06575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYD00_06580	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EYD00_06585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYD00_06590	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYD00_06595	COG1472	Belongs to the glycosyl hydrolase 3 family
EYD00_06605	COG0018	arginyl-trna synthetase
EYD00_06610	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYD00_06615	COG0316	Belongs to the HesB IscA family
EYD00_06645	COG0525	valine-tRNA ligase activity
EYD00_06655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EYD00_06690	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYD00_06695	COG1546	Belongs to the CinA family
EYD00_06695	COG1058	Belongs to the CinA family
EYD00_06700	COG0589	response to stress
EYD00_06705	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EYD00_06715	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EYD00_06730	COG1914	H( )-stimulated, divalent metal cation uptake system
EYD00_06745	COG1132	(ABC) transporter
EYD00_06750	COG0628	permease
EYD00_06790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYD00_06800	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYD00_06810	COG0302	gtp cyclohydrolase
EYD00_06815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EYD00_06820	COG1752	Esterase of the alpha-beta hydrolase superfamily
EYD00_06825	COG0516	GMP reductase activity
EYD00_06825	COG0517	IMP dehydrogenase activity
EYD00_06860	COG1760	l-serine dehydratase
EYD00_06895	COG0583	DNA-binding transcription factor activity
EYD00_06910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYD00_06910	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYD00_06915	COG0347	Belongs to the P(II) protein family
EYD00_06920	COG0174	glutamine synthetase
EYD00_06950	COG0697	spore germination
EYD00_06965	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYD00_06975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYD00_07005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYD00_07010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYD00_07015	COG2186	Transcriptional regulator
EYD00_07035	COG1129	ABC transporter
EYD00_07040	COG1183	phosphatidylcholine synthase activity
EYD00_07045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYD00_07050	COG0679	Auxin Efflux Carrier
EYD00_07055	COG0785	Cytochrome C biogenesis protein
EYD00_07080	COG1278	Cold shock
EYD00_07240	COG3750	Belongs to the UPF0335 family
EYD00_07380	COG0577	efflux transmembrane transporter activity
EYD00_07380	COG1136	(ABC) transporter
EYD00_07385	COG0577	efflux transmembrane transporter activity
EYD00_07385	COG1136	(ABC) transporter
EYD00_07410	COG2151	metal-sulfur cluster biosynthetic enzyme
EYD00_07415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EYD00_07420	COG0719	Fe-S assembly protein
EYD00_07425	COG0396	ATPase activity
EYD00_07430	COG0719	Fe-S assembly protein
EYD00_07435	COG1104	cysteine desulfurase activity
EYD00_07440	COG2945	thiolester hydrolase activity
EYD00_07450	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EYD00_07455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYD00_07465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYD00_07470	COG2833	Protein of unknown function (DUF455)
EYD00_07475	COG0739	heme binding
EYD00_07480	COG0513	Belongs to the DEAD box helicase family
EYD00_07510	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EYD00_07520	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYD00_07525	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYD00_07530	COG0047	phosphoribosylformylglycinamidine synthase activity
EYD00_07545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYD00_07555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYD00_07575	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EYD00_07580	COG2814	Major facilitator Superfamily
EYD00_07585	COG0483	inositol monophosphate 1-phosphatase activity
EYD00_07590	COG0483	inositol monophosphate 1-phosphatase activity
EYD00_07595	COG0037	tRNA processing
EYD00_07600	COG2066	Belongs to the glutaminase family
EYD00_07605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYD00_07610	COG0861	Integral membrane protein TerC family
EYD00_07635	COG1280	lysine exporter protein (LysE YggA)
EYD00_07650	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EYD00_07655	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
EYD00_07665	COG0538	isocitrate dehydrogenase activity
EYD00_07675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYD00_07685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYD00_07690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_07695	COG2313	pseudouridylate synthase activity
EYD00_07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_07715	COG4215	(ABC) transporter
EYD00_07725	COG5425	PFAM Usg family protein
EYD00_07735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_07740	COG1522	sequence-specific DNA binding
EYD00_07745	COG1573	uracil-dna glycosylase
EYD00_07755	COG2205	protein histidine kinase activity
EYD00_07755	COG2202	Pas domain
EYD00_07765	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EYD00_07770	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EYD00_07785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYD00_07790	COG0842	Transport permease protein
EYD00_07795	COG1131	(ABC) transporter
EYD00_07815	COG0840	transmembrane signaling receptor activity
EYD00_07825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYD00_07830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYD00_07845	COG0129	dihydroxy-acid dehydratase activity
EYD00_07850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYD00_07855	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EYD00_07865	COG0203	ribosomal protein L17
EYD00_07870	COG0202	RNA polymerase activity
EYD00_07875	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYD00_07880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EYD00_07885	COG0563	adenylate kinase activity
EYD00_07890	COG0201	protein transport
EYD00_07895	COG0200	Binds to the 23S rRNA
EYD00_07900	COG1841	ribosomal large subunit assembly
EYD00_07905	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYD00_07910	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EYD00_07915	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYD00_07920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYD00_07925	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYD00_07930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EYD00_07935	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EYD00_07940	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EYD00_07945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYD00_07950	COG0255	Belongs to the universal ribosomal protein uL29 family
EYD00_07955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYD00_07960	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EYD00_07965	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYD00_07970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EYD00_07975	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYD00_07980	COG0089	rRNA binding
EYD00_07985	COG0088	Forms part of the polypeptide exit tunnel
EYD00_07990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYD00_07995	COG0051	transcription antitermination factor activity, RNA binding
EYD00_08000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYD00_08005	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYD00_08010	COG0049	tRNA binding
EYD00_08015	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYD00_08035	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYD00_08040	COG0085	RNA polymerase activity
EYD00_08045	COG0222	ribosome binding
EYD00_08050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EYD00_08055	COG0081	regulation of translation
EYD00_08060	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EYD00_08080	COG1086	Polysaccharide biosynthesis protein
EYD00_08085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EYD00_08090	COG0861	Integral membrane protein TerC family
EYD00_08125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYD00_08130	COG1607	acyl-coa hydrolase
EYD00_08145	COG2910	NAD(P)H-binding
EYD00_08165	COG0556	nucleotide-excision repair
EYD00_08175	COG2382	esterase
EYD00_08195	COG0484	heat shock protein binding
EYD00_08230	COG1840	ABC-type Fe3 transport system, periplasmic component
EYD00_08240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYD00_08245	COG4154	Belongs to the RbsD FucU family
EYD00_08255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EYD00_08265	COG2207	Transcriptional regulator
EYD00_08270	COG1064	alcohol dehydrogenase
EYD00_08275	COG1252	NADH dehydrogenase
EYD00_08280	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EYD00_08290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYD00_08315	COG0656	L-ascorbic acid biosynthetic process
EYD00_08330	COG0440	acetolactate synthase activity
EYD00_08335	COG0028	Belongs to the TPP enzyme family
EYD00_08345	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYD00_08350	COG0560	Phosphoserine phosphatase
EYD00_08360	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_08370	COG0330	HflC and HflK could
EYD00_08375	COG0330	HflC and HflK could
EYD00_08385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EYD00_08420	COG0277	FAD linked oxidase domain protein
EYD00_08425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYD00_08465	COG1335	isochorismatase
EYD00_08495	COG2264	protein methyltransferase activity
EYD00_08500	COG1999	signal sequence binding
EYD00_08505	COG0835	chemotaxis
EYD00_08515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYD00_08520	COG0583	DNA-binding transcription factor activity
EYD00_08530	COG1247	-acetyltransferase
EYD00_08540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYD00_08545	COG0497	DNA recombination
EYD00_08550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EYD00_08560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYD00_08565	COG0849	cell division
EYD00_08570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EYD00_08575	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYD00_08580	COG0477	Major facilitator Superfamily
EYD00_08585	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYD00_08590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EYD00_08595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYD00_08605	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYD00_08610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYD00_08620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYD00_08635	COG0275	rRNA processing
EYD00_08640	COG2001	Belongs to the MraZ family
EYD00_08665	COG3023	N-Acetylmuramoyl-L-alanine amidase
EYD00_08670	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EYD00_08695	COG4106	trans-aconitate 2-methyltransferase activity
EYD00_08725	COG2267	carboxylic ester hydrolase activity
EYD00_08730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EYD00_08745	COG0251	oxidation-reduction process
EYD00_08760	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_08765	COG2814	Major facilitator Superfamily
EYD00_08785	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_08790	COG0174	glutamine synthetase
EYD00_08795	COG0531	amino acid
EYD00_08805	COG1737	Transcriptional regulator
EYD00_08820	COG1178	ABC-type Fe3 transport system permease component
EYD00_08830	COG3842	ATPase activity
EYD00_08885	COG2968	Membrane
EYD00_08895	COG0432	Pfam Uncharacterised protein family UPF0047
EYD00_08910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYD00_08915	COG0358	DNA primase activity
EYD00_08930	COG0505	Belongs to the CarA family
EYD00_08935	COG0534	Mate efflux family protein
EYD00_08950	COG2321	neutral zinc metallopeptidase
EYD00_08965	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EYD00_08975	COG3706	GGDEF domain
EYD00_08980	COG1573	uracil-dna glycosylase
EYD00_08990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYD00_09000	COG1522	sequence-specific DNA binding
EYD00_09005	COG0492	ferredoxin-NADP+ reductase activity
EYD00_09010	COG0583	DNA-binding transcription factor activity
EYD00_09020	COG1902	pentaerythritol trinitrate reductase activity
EYD00_09050	COG0387	Pfam Sodium calcium exchanger
EYD00_09075	COG1278	Cold shock
EYD00_09080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYD00_09095	COG1846	Transcriptional regulator
EYD00_09100	COG0745	RESPONSE REGULATOR receiver
EYD00_09105	COG2205	protein histidine kinase activity
EYD00_09110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYD00_09130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYD00_09155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYD00_09165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EYD00_09180	COG0840	transmembrane signaling receptor activity
EYD00_09185	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_09195	COG5001	Diguanylate cyclase
EYD00_09195	COG3300	MHYT domain
EYD00_09200	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EYD00_09205	COG5001	Diguanylate cyclase
EYD00_09215	COG0193	aminoacyl-tRNA hydrolase activity
EYD00_09225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EYD00_09245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYD00_09250	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EYD00_09250	COG2857	Cytochrome c1
EYD00_09270	COG1132	(ABC) transporter
EYD00_09275	COG1132	(ABC) transporter
EYD00_09285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EYD00_09300	COG0408	coproporphyrinogen oxidase activity
EYD00_09330	COG0714	Associated with various cellular activities
EYD00_09350	COG0454	-acetyltransferase
EYD00_09355	COG0583	DNA-binding transcription factor activity
EYD00_09365	COG0477	Major facilitator Superfamily
EYD00_09375	COG0435	Glutathione S-transferase
EYD00_09390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYD00_09405	COG3135	benzoate transporter
EYD00_09420	COG1595	DNA-templated transcription, initiation
EYD00_09430	COG0740	serine-type endopeptidase activity
EYD00_09445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EYD00_09450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYD00_09475	COG4175	Glycine betaine
EYD00_09490	COG1435	thymidine kinase activity
EYD00_09510	COG2862	Uncharacterized protein family, UPF0114
EYD00_09515	COG4771	TonB-dependent receptor
EYD00_09515	COG1629	transport
EYD00_09525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYD00_09525	COG0512	Glutamine amidotransferase of anthranilate synthase
EYD00_09540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYD00_09555	COG0366	Alpha amylase catalytic
EYD00_09560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_09575	COG1160	GTP binding
EYD00_09595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EYD00_09605	COG0024	Methionine aminopeptidase
EYD00_09615	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_09635	COG0583	DNA-binding transcription factor activity
EYD00_09650	COG0402	S-adenosylhomocysteine deaminase activity
EYD00_09660	COG1304	FMN binding
EYD00_09670	COG1309	transcriptional regulator
EYD00_09675	COG1686	Belongs to the peptidase S11 family
EYD00_09685	COG2351	hydroxyisourate hydrolase activity
EYD00_09690	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EYD00_09715	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EYD00_09725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_09725	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EYD00_09730	COG0784	Response regulator, receiver
EYD00_09730	COG2205	protein histidine kinase activity
EYD00_09730	COG5002	protein histidine kinase activity
EYD00_09735	COG0513	Belongs to the DEAD box helicase family
EYD00_09745	COG2259	Doxx family
EYD00_09750	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_09760	COG2308	Evidence 4 Homologs of previously reported genes of
EYD00_09770	COG1305	Transglutaminase-like
EYD00_09790	COG0588	phosphoglycerate mutase activity
EYD00_09800	COG4214	carbohydrate transport
EYD00_09810	COG4213	ABC transporter substrate-binding protein
EYD00_09845	COG0840	transmembrane signaling receptor activity
EYD00_09870	COG1215	transferase activity, transferring glycosyl groups
EYD00_09885	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EYD00_09905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYD00_09910	COG2346	COG2346, Truncated hemoglobins
EYD00_09930	COG1309	transcriptional regulator
EYD00_09945	COG0494	nUDIX hydrolase
EYD00_09960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_09965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_09990	COG1234	tRNA 3'-trailer cleavage
EYD00_09995	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EYD00_10000	COG0830	nickel cation binding
EYD00_10005	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EYD00_10020	COG0804	urea catabolic process
EYD00_10025	COG1442	glycosyl transferase family 8
EYD00_10030	COG3755	Protein conserved in bacteria
EYD00_10040	COG0832	Belongs to the urease beta subunit family
EYD00_10045	COG3813	Protein conserved in bacteria
EYD00_10050	COG0831	urea catabolic process
EYD00_10055	COG0829	nickel cation binding
EYD00_10085	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYD00_10105	COG0174	glutamine synthetase
EYD00_10110	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_10115	COG2198	Histidine kinase
EYD00_10115	COG0784	Response regulator, receiver
EYD00_10115	COG5002	protein histidine kinase activity
EYD00_10130	COG0726	polysaccharide deacetylase
EYD00_10150	COG0411	ABC transporter
EYD00_10165	COG1218	3'(2'),5'-bisphosphate nucleotidase
EYD00_10245	COG0564	pseudouridine synthase activity
EYD00_10255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYD00_10265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EYD00_10295	COG0346	lactoylglutathione lyase activity
EYD00_10305	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EYD00_10315	COG2832	Protein of unknown function (DUF454)
EYD00_10320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EYD00_10325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_10330	COG4558	Periplasmic binding protein
EYD00_10340	COG3721	Heme iron utilization protein
EYD00_10365	COG3657	addiction module killer protein
EYD00_10375	COG2205	protein histidine kinase activity
EYD00_10415	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_10420	COG4605	iron ion homeostasis
EYD00_10425	COG4604	ABC transporter, ATP-binding protein
EYD00_10430	COG0783	Belongs to the Dps family
EYD00_10445	COG0656	L-ascorbic acid biosynthetic process
EYD00_10450	COG2814	Major facilitator Superfamily
EYD00_10460	COG0583	DNA-binding transcription factor activity
EYD00_10470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_10490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYD00_10495	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EYD00_10500	COG0288	reversible hydration of carbon dioxide
EYD00_10510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EYD00_10530	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EYD00_10535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYD00_10540	COG0778	Nitroreductase
EYD00_10545	COG2267	carboxylic ester hydrolase activity
EYD00_10550	COG0251	oxidation-reduction process
EYD00_10555	COG1335	isochorismatase
EYD00_10560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_10570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_10585	COG1175	transmembrane transport
EYD00_10590	COG0395	ABC-type sugar transport system, permease component
EYD00_10595	COG3842	ATPase activity
EYD00_10600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_10610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYD00_10625	COG4608	Belongs to the ABC transporter superfamily
EYD00_10630	COG0444	Belongs to the ABC transporter superfamily
EYD00_10640	COG0601	transmembrane transport
EYD00_10660	COG0392	lysyltransferase activity
EYD00_10660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EYD00_10690	COG0642	Histidine kinase
EYD00_10695	COG0745	RESPONSE REGULATOR receiver
EYD00_10705	COG1902	pentaerythritol trinitrate reductase activity
EYD00_10705	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYD00_10715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_10740	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_10760	COG1522	sequence-specific DNA binding
EYD00_10765	COG1335	isochorismatase
EYD00_10775	COG0604	alcohol dehydrogenase
EYD00_10775	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_10775	COG3321	synthase
EYD00_10780	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_10785	COG2207	Transcriptional regulator
EYD00_10835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYD00_10845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_10850	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYD00_10860	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EYD00_10865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EYD00_10870	COG1509	lysine 2,3-aminomutase activity
EYD00_10890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_10895	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYD00_10900	COG4149	molybdate abc transporter
EYD00_10905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EYD00_10920	COG2022	thiamine diphosphate biosynthetic process
EYD00_10935	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EYD00_10940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYD00_10950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYD00_10975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EYD00_10975	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYD00_11020	COG4166	transmembrane transport
EYD00_11025	COG0601	transmembrane transport
EYD00_11030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_11040	COG0438	transferase activity, transferring glycosyl groups
EYD00_11050	COG3142	Participates in the control of copper homeostasis
EYD00_11055	COG2814	Major facilitator Superfamily
EYD00_11070	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_11075	COG1737	Transcriptional regulator
EYD00_11085	COG3842	ATPase activity
EYD00_11095	COG0395	ABC-type sugar transport system, permease component
EYD00_11125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYD00_11130	COG1940	carbohydrate kinase activity
EYD00_11140	COG0671	phosphoesterase, PA-phosphatase related
EYD00_11145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EYD00_11150	COG0156	8-amino-7-oxononanoate synthase activity
EYD00_11160	COG0729	surface antigen
EYD00_11170	COG0835	chemotaxis
EYD00_11180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EYD00_11185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYD00_11190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYD00_11195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYD00_11200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYD00_11205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYD00_11220	COG4974	Belongs to the 'phage' integrase family
EYD00_11245	COG1280	lysine exporter protein (LysE YggA)
EYD00_11255	COG0508	dehydrogenase complex catalyzes the overall conversion of
EYD00_11265	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EYD00_11270	COG0045	succinate-CoA ligase (ADP-forming) activity
EYD00_11275	COG0039	L-malate dehydrogenase activity
EYD00_11280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EYD00_11315	COG2264	protein methyltransferase activity
EYD00_11330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYD00_11335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EYD00_11340	COG0181	hydroxymethylbilane synthase activity
EYD00_11365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYD00_11375	COG1872	DUF167
EYD00_11380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EYD00_11400	COG0339	signal peptide processing
EYD00_11410	COG1846	Transcriptional regulator
EYD00_11415	COG2814	Major facilitator Superfamily
EYD00_11420	COG0137	argininosuccinate synthase activity
EYD00_11430	COG1280	lysine exporter protein (LysE YggA)
EYD00_11440	COG4120	Belongs to the binding-protein-dependent transport system permease family
EYD00_11450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYD00_11465	COG2154	pterin-4-alpha-carbinolamine dehydratase
EYD00_11470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EYD00_11475	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EYD00_11485	COG4181	ATPase activity
EYD00_11495	COG0670	Belongs to the BI1 family
EYD00_11510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYD00_11515	COG4133	protoheme IX ABC transporter activity
EYD00_11525	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYD00_11530	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EYD00_11545	COG3706	GGDEF domain
EYD00_11555	COG2917	probably involved in intracellular septation
EYD00_11560	COG0552	protein localization to endoplasmic reticulum
EYD00_11565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYD00_11570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYD00_11585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYD00_11590	COG0287	Prephenate dehydrogenase
EYD00_11590	COG1605	Chorismate mutase
EYD00_11595	COG0228	four-way junction DNA binding
EYD00_11600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYD00_11605	COG0336	Belongs to the RNA methyltransferase TrmD family
EYD00_11615	COG0335	large ribosomal subunit rRNA binding
EYD00_11625	COG0765	amino acid transport
EYD00_11640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYD00_11645	COG4783	chaperone-mediated protein folding
EYD00_11655	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EYD00_11685	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYD00_11695	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYD00_11700	COG0142	geranyltranstransferase activity
EYD00_11705	COG2885	chlorophyll binding
EYD00_11710	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYD00_11715	COG2223	nitrite transmembrane transporter activity
EYD00_11720	COG1349	DNA-binding transcription factor activity
EYD00_11725	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EYD00_11730	COG2197	response regulator
EYD00_11735	COG1132	(ABC) transporter
EYD00_11740	COG3459	Glycosyltransferase 36 associated
EYD00_11745	COG1473	amidohydrolase
EYD00_11755	COG0579	oxidoreductase
EYD00_11765	COG0129	dihydroxy-acid dehydratase activity
EYD00_11770	COG2084	Dehydrogenase
EYD00_11775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYD00_11780	COG0277	FAD linked oxidase domain protein
EYD00_11785	COG2186	Transcriptional regulator
EYD00_11795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EYD00_11800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYD00_11805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_11810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYD00_11820	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYD00_11825	COG0495	leucyl-tRNA aminoacylation
EYD00_11845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EYD00_11860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EYD00_11865	COG1946	Acyl-CoA thioesterase
EYD00_11870	COG0347	Belongs to the P(II) protein family
EYD00_11875	COG0004	ammonium transporteR
EYD00_11880	COG1674	ftsk spoiiie
EYD00_11885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EYD00_11900	COG0745	RESPONSE REGULATOR receiver
EYD00_11910	COG1329	Transcriptional regulator
EYD00_11915	COG2902	Dehydrogenase
EYD00_11920	COG2270	Major facilitator Superfamily
EYD00_11935	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_11950	COG0494	nUDIX hydrolase
EYD00_11960	COG0793	Belongs to the peptidase S41A family
EYD00_11970	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EYD00_11975	COG0799	negative regulation of ribosome biogenesis
EYD00_11980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYD00_11985	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYD00_11990	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EYD00_11995	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYD00_12010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYD00_12015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYD00_12040	COG0066	3-isopropylmalate dehydratase activity
EYD00_12045	COG0473	3-isopropylmalate dehydrogenase activity
EYD00_12050	COG1858	cytochrome C peroxidase
EYD00_12055	COG1797	cobyrinic acid a,c-diamide synthase activity
EYD00_12060	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYD00_12060	COG1648	precorrin-2 dehydrogenase activity
EYD00_12065	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EYD00_12130	COG1492	cobalamin metabolic process
EYD00_12145	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_12150	COG3254	rhamnose metabolic process
EYD00_12160	COG1063	alcohol dehydrogenase
EYD00_12180	COG4214	carbohydrate transport
EYD00_12185	COG1129	ABC transporter
EYD00_12190	COG2186	Transcriptional regulator
EYD00_12195	COG2721	sulfolactate sulfo-lyase activity
EYD00_12200	COG0138	bifunctional purine biosynthesis protein purh
EYD00_12210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYD00_12210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYD00_12215	COG0501	Belongs to the peptidase M48B family
EYD00_12225	COG1475	DNA binding
EYD00_12230	COG1192	Involved in chromosome partitioning
EYD00_12235	COG0357	Ribosomal RNA small subunit methyltransferase G
EYD00_12240	COG0445	tRNA wobble uridine modification
EYD00_12245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYD00_12250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EYD00_12260	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EYD00_12265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EYD00_12270	COG0424	maF-like protein
EYD00_12275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYD00_12280	COG0237	dephospho-CoA kinase activity
EYD00_12290	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EYD00_12295	COG3030	protein affecting phage T7 exclusion by the F plasmid
EYD00_12305	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EYD00_12320	COG0187	DNA topoisomerase II activity
EYD00_12330	COG0179	Fumarylacetoacetate (FAA) hydrolase
EYD00_12345	COG0135	phosphoribosylanthranilate isomerase activity
EYD00_12350	COG0133	tryptophan synthase activity
EYD00_12355	COG0159	tryptophan synthase activity
EYD00_12360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EYD00_12375	COG1074	ATP-dependent DNA helicase activity
EYD00_12385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EYD00_12395	COG2205	protein histidine kinase activity
EYD00_12405	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EYD00_12410	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYD00_12415	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYD00_12415	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYD00_12420	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EYD00_12425	COG0642	Histidine kinase
EYD00_12430	COG0745	RESPONSE REGULATOR receiver
EYD00_12435	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EYD00_12445	COG1652	LysM domain
EYD00_12450	COG1072	(Pantothenic acid kinase))
EYD00_12455	COG0140	phosphoribosyl-ATP diphosphatase activity
EYD00_12460	COG0107	imidazoleglycerol-phosphate synthase activity
EYD00_12465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EYD00_12470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYD00_12480	COG0131	Imidazoleglycerol-phosphate dehydratase
EYD00_12485	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EYD00_12490	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EYD00_12500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EYD00_12515	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYD00_12525	COG1643	Atp-dependent helicase
EYD00_12570	COG0514	ATP-dependent DNA helicase (RecQ)
EYD00_12595	COG1072	(Pantothenic acid kinase))
EYD00_12605	COG1780	Probably involved in ribonucleotide reductase function
EYD00_12625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYD00_12650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_12660	COG2813	Specifically methylates the guanine in position
EYD00_12665	COG1185	polyribonucleotide nucleotidyltransferase activity
EYD00_12670	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYD00_12675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYD00_12680	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYD00_12685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYD00_12685	COG3064	Membrane
EYD00_12700	COG0779	Required for maturation of 30S ribosomal subunits
EYD00_12705	COG2814	Major facilitator Superfamily
EYD00_12710	COG2951	lytic endotransglycosylase activity
EYD00_12715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYD00_12725	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYD00_12730	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYD00_12745	COG2816	NAD+ diphosphatase activity
EYD00_12750	COG1605	Chorismate mutase
EYD00_12750	COG0077	Prephenate dehydratase
EYD00_12755	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EYD00_12760	COG3474	cytochrome
EYD00_12770	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EYD00_12775	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYD00_12785	COG1278	Cold shock
EYD00_12790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYD00_12800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYD00_12800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYD00_12810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYD00_12845	COG2900	Belongs to the SlyX family
EYD00_12855	COG0484	heat shock protein binding
EYD00_12860	COG0443	Heat shock 70 kDa protein
EYD00_12875	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EYD00_12905	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EYD00_12910	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EYD00_12915	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EYD00_12925	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYD00_12930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EYD00_12935	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EYD00_12945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EYD00_12950	COG1845	cytochrome c oxidase, subunit III
EYD00_12955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYD00_12960	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EYD00_12965	COG0477	Major facilitator Superfamily
EYD00_12970	COG0070	glutamate synthase
EYD00_12970	COG0069	glutamate synthase activity
EYD00_12970	COG0067	glutamate synthase
EYD00_12975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EYD00_12990	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EYD00_13000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYD00_13035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_13055	COG0848	biopolymer transport protein
EYD00_13065	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYD00_13080	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EYD00_13085	COG3454	Phosphonate metabolism
EYD00_13090	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EYD00_13095	COG3639	organic phosphonate transmembrane transporter activity
EYD00_13100	COG3639	organic phosphonate transmembrane transporter activity
EYD00_13105	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EYD00_13110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EYD00_13120	COG4778	phosphonate C-P lyase system protein PhnL
EYD00_13125	COG4107	phosphonate C-P lyase system protein PhnK
EYD00_13130	COG3627	carbon phosphorus lyase activity
EYD00_13135	COG3626	phosphonate metabolism
EYD00_13140	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EYD00_13145	COG3624	Phosphonate C-P lyase system protein PhnG
EYD00_13150	COG2188	Transcriptional regulator
EYD00_13155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYD00_13160	COG0837	glucose binding
EYD00_13165	COG1803	Methylglyoxal synthase
EYD00_13170	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
EYD00_13175	COG4166	transmembrane transport
EYD00_13180	COG4174	ABC transporter (Permease)
EYD00_13185	COG4239	(ABC) transporter, permease
EYD00_13190	COG4172	Belongs to the ABC transporter superfamily
EYD00_13195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_13200	COG0174	glutamine synthetase
EYD00_13205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_13210	COG3265	gluconokinase activity
EYD00_13215	COG1174	glycine betaine transport
EYD00_13220	COG1125	glycine betaine transport
EYD00_13225	COG1174	glycine betaine transport
EYD00_13230	COG1732	Glycine betaine
EYD00_13240	COG1959	2 iron, 2 sulfur cluster binding
EYD00_13245	COG1840	ABC-type Fe3 transport system, periplasmic component
EYD00_13260	COG0697	spore germination
EYD00_13275	COG0791	NLP P60 protein
EYD00_13285	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYD00_13290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EYD00_13325	COG4964	Belongs to the GSP D family
EYD00_13370	COG3422	double-strand break repair
EYD00_13375	COG3757	hydrolase, family 25
EYD00_13380	COG0697	spore germination
EYD00_13385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYD00_13415	COG0481	GTPase activity
EYD00_13420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYD00_13435	COG1396	sequence-specific DNA binding
EYD00_13450	COG1917	Cupin 2, conserved barrel domain protein
EYD00_13450	COG2169	Transcriptional regulator
EYD00_13455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYD00_13480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYD00_13485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EYD00_13490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EYD00_13500	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYD00_13505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYD00_13505	COG0072	phenylalanine-tRNA ligase activity
EYD00_13510	COG0667	Aldo Keto reductase
EYD00_13530	COG4977	sequence-specific DNA binding
EYD00_13555	COG1570	exodeoxyribonuclease VII activity
EYD00_13560	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_13570	COG1846	Transcriptional regulator
EYD00_13575	COG0697	spore germination
EYD00_13580	COG2309	aminopeptidase activity
EYD00_13590	COG1393	Belongs to the ArsC family
EYD00_13615	COG0519	Catalyzes the synthesis of GMP from XMP
EYD00_13615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYD00_13630	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EYD00_13660	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EYD00_13670	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EYD00_13680	COG1968	undecaprenyl-diphosphatase activity
EYD00_13705	COG0284	orotidine-5'-phosphate decarboxylase activity
EYD00_13715	COG3963	phosphatidate phosphatase activity
EYD00_13720	COG0592	DNA-directed DNA polymerase activity
EYD00_13725	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYD00_13730	COG0792	nuclease activity
EYD00_13740	COG1653	transport
EYD00_13745	COG1175	transmembrane transport
EYD00_13755	COG3842	ATPase activity
EYD00_13765	COG0189	ligase activity
EYD00_13775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EYD00_13780	COG1280	lysine exporter protein (LysE YggA)
EYD00_13785	COG0756	dUTP diphosphatase activity
EYD00_13790	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYD00_13795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYD00_13810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EYD00_13815	COG2226	methyltransferase
EYD00_13820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EYD00_13825	COG1024	Enoyl-CoA hydratase
EYD00_13830	COG0268	Binds directly to 16S ribosomal RNA
EYD00_13885	COG0756	dUTP diphosphatase activity
EYD00_13960	COG3727	T/G mismatch-specific endonuclease activity
EYD00_13995	COG4977	sequence-specific DNA binding
EYD00_14015	COG1132	(ABC) transporter
EYD00_14075	COG0110	maltose O-acetyltransferase activity
EYD00_14085	COG0840	transmembrane signaling receptor activity
EYD00_14090	COG1049	propionate catabolic process, 2-methylcitrate cycle
EYD00_14095	COG2233	PERMEase
EYD00_14120	COG0395	ABC-type sugar transport system, permease component
EYD00_14125	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYD00_14135	COG3842	ATPase activity
EYD00_14150	COG0765	amino acid transport
EYD00_14160	COG2186	Transcriptional regulator
EYD00_14195	COG1653	transport
EYD00_14200	COG1175	transmembrane transport
EYD00_14205	COG0395	ABC-type sugar transport system, permease component
EYD00_14210	COG3842	ATPase activity
EYD00_14220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_14225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_14230	COG1116	anion transmembrane transporter activity
EYD00_14235	COG0395	ABC-type sugar transport system, permease component
EYD00_14240	COG1175	transmembrane transport
EYD00_14280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYD00_14300	COG3842	ATPase activity
EYD00_14305	COG0395	ABC-type sugar transport system, permease component
EYD00_14310	COG1175	transmembrane transport
EYD00_14315	COG1653	transport
EYD00_14320	COG1309	transcriptional regulator
EYD00_14325	COG0673	inositol 2-dehydrogenase activity
EYD00_14340	COG0673	inositol 2-dehydrogenase activity
EYD00_14345	COG1278	Cold shock
EYD00_14355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYD00_14380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYD00_14385	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYD00_14405	COG0395	ABC-type sugar transport system, permease component
EYD00_14410	COG1175	transmembrane transport
EYD00_14430	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_14435	COG3618	amidohydrolase
EYD00_14440	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_14445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_14450	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_14455	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
EYD00_14460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYD00_14465	COG2186	Transcriptional regulator
EYD00_14515	COG2223	nitrite transmembrane transporter activity
EYD00_14520	COG0583	DNA-binding transcription factor activity
EYD00_14525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYD00_14535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_14540	COG2084	Dehydrogenase
EYD00_14555	COG1609	Transcriptional regulator
EYD00_14560	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYD00_14570	COG1121	(ABC) transporter
EYD00_14575	COG0523	cobalamin synthesis protein
EYD00_14590	COG0523	cobalamin synthesis protein
EYD00_14595	COG1653	transport
EYD00_14600	COG1175	transmembrane transport
EYD00_14605	COG0395	ABC-type sugar transport system, permease component
EYD00_14610	COG3842	ATPase activity
EYD00_14625	COG3047	cAMP biosynthetic process
EYD00_14650	COG0583	DNA-binding transcription factor activity
EYD00_14655	COG1879	ABC-type sugar transport system periplasmic component
EYD00_14660	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_14665	COG1129	ABC transporter
EYD00_14675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYD00_14680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_14690	COG3257	ureidoglycine aminohydrolase activity
EYD00_14700	COG3300	MHYT domain
EYD00_14700	COG5001	Diguanylate cyclase
EYD00_14705	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYD00_14710	COG1609	Transcriptional regulator
EYD00_14720	COG0673	inositol 2-dehydrogenase activity
EYD00_14725	COG1082	Xylose isomerase domain protein TIM barrel
EYD00_14740	COG1609	Transcriptional regulator
EYD00_14750	COG0183	Belongs to the thiolase family
EYD00_14755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EYD00_14765	COG1414	Transcriptional regulator
EYD00_14780	COG0583	DNA-binding transcription factor activity
EYD00_14790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYD00_14795	COG3485	protocatechuate 3,4-dioxygenase
EYD00_14800	COG3485	protocatechuate 3,4-dioxygenase
EYD00_14810	COG0765	amino acid transport
EYD00_14815	COG0765	amino acid transport
EYD00_14820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_14825	COG1126	abc transporter atp-binding protein
EYD00_14830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYD00_14835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EYD00_14860	COG0747	negative chemotaxis
EYD00_14870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_14885	COG0683	leucine binding
EYD00_14915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_14920	COG3962	Belongs to the TPP enzyme family
EYD00_14930	COG3718	enzyme involved in inositol metabolism
EYD00_14940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYD00_14945	COG1609	Transcriptional regulator
EYD00_14950	COG1846	Transcriptional regulator
EYD00_14960	COG0523	cobalamin synthesis protein
EYD00_15005	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EYD00_15025	COG0800	Aldolase
EYD00_15045	COG5001	Diguanylate cyclase
EYD00_15045	COG3300	MHYT domain
EYD00_15055	COG2011	ABC-type metal ion transport system permease component
EYD00_15060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYD00_15065	COG0778	Nitroreductase
EYD00_15085	COG2115	Belongs to the xylose isomerase family
EYD00_15095	COG1070	Carbohydrate kinase
EYD00_15100	COG1609	Transcriptional regulator
EYD00_15115	COG1309	transcriptional regulator
EYD00_15120	COG1253	flavin adenine dinucleotide binding
EYD00_15130	COG3273	potassium ion transport
EYD00_15130	COG0471	metal ion transport
EYD00_15135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYD00_15140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYD00_15150	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYD00_15155	COG1121	(ABC) transporter
EYD00_15160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYD00_15165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYD00_15175	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_15180	COG1414	Transcriptional regulator
EYD00_15185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EYD00_15195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYD00_15225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYD00_15240	COG0395	ABC-type sugar transport system, permease component
EYD00_15255	COG2390	Transcriptional regulator
EYD00_15260	COG4172	Belongs to the ABC transporter superfamily
EYD00_15265	COG1473	amidohydrolase
EYD00_15275	COG0601	transmembrane transport
EYD00_15280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_15290	COG0693	protein deglycase activity
EYD00_15295	COG0154	amidase activity
EYD00_15300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_15310	COG0747	negative chemotaxis
EYD00_15315	COG0583	DNA-binding transcription factor activity
EYD00_15320	COG4608	Belongs to the ABC transporter superfamily
EYD00_15325	COG0444	Belongs to the ABC transporter superfamily
EYD00_15335	COG0601	transmembrane transport
EYD00_15340	COG0747	negative chemotaxis
EYD00_15355	COG1473	amidohydrolase
EYD00_15365	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EYD00_15375	COG3842	ATPase activity
EYD00_15385	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYD00_15395	COG1609	Transcriptional regulator
EYD00_15400	COG0583	DNA-binding transcription factor activity
EYD00_15405	COG1960	acyl-CoA dehydrogenase activity
EYD00_15410	COG4774	siderophore transport
EYD00_15410	COG1629	transport
EYD00_15425	COG1120	ATPase activity
EYD00_15430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_15435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_15445	COG2375	cellular response to nickel ion
EYD00_15455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYD00_15460	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EYD00_15460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EYD00_15470	COG1169	isochorismate synthase
EYD00_15475	COG1021	2,3-dihydroxybenzoate-AMP ligase
EYD00_15480	COG1535	isochorismatase
EYD00_15480	COG3433	isochorismatase activity
EYD00_15485	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_15490	COG2977	Belongs to the P-Pant transferase superfamily
EYD00_15505	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_15510	COG0488	(ABC) transporter
EYD00_15535	COG0778	Nitroreductase
EYD00_15555	COG0277	FAD linked oxidase domain protein
EYD00_15570	COG0747	negative chemotaxis
EYD00_15580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_15585	COG4172	Belongs to the ABC transporter superfamily
EYD00_15595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_15605	COG0431	NADPH-dependent FMN reductase
EYD00_15610	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_15635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_15640	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EYD00_15645	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_15655	COG0583	DNA-binding transcription factor activity
EYD00_15680	COG0673	inositol 2-dehydrogenase activity
EYD00_15690	COG1609	Transcriptional regulator
EYD00_15695	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_15700	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_15705	COG1129	ABC transporter
EYD00_15710	COG1879	ABC-type sugar transport system periplasmic component
EYD00_15730	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYD00_15730	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYD00_15740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_15755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYD00_15765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYD00_15770	COG1177	transmembrane transport
EYD00_15775	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYD00_15780	COG3842	ATPase activity
EYD00_15795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYD00_15800	COG0583	DNA-binding transcription factor activity
EYD00_15805	COG2197	response regulator
EYD00_15810	COG3237	CsbD-like
EYD00_15825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_15860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_15870	COG1522	sequence-specific DNA binding
EYD00_15875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_15890	COG1126	abc transporter atp-binding protein
EYD00_15900	COG1473	amidohydrolase
EYD00_15905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_15910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_15915	COG1959	2 iron, 2 sulfur cluster binding
EYD00_15925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYD00_15930	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_15950	COG1960	acyl-CoA dehydrogenase activity
EYD00_15985	COG0667	Aldo Keto reductase
EYD00_15995	COG0583	DNA-binding transcription factor activity
EYD00_16005	COG4166	transmembrane transport
EYD00_16015	COG0747	negative chemotaxis
EYD00_16020	COG1473	amidohydrolase
EYD00_16025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_16065	COG4608	Belongs to the ABC transporter superfamily
EYD00_16070	COG0444	Belongs to the ABC transporter superfamily
EYD00_16080	COG0601	transmembrane transport
EYD00_16090	COG2186	Transcriptional regulator
EYD00_16105	COG0300	oxidoreductase activity
EYD00_16115	COG3453	Protein conserved in bacteria
EYD00_16115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYD00_16120	COG0640	Transcriptional regulator
EYD00_16130	COG2391	methyltransferase activity
EYD00_16135	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYD00_16155	COG0022	dehydrogenase e1 component
EYD00_16165	COG1960	acyl-CoA dehydrogenase activity
EYD00_16175	COG1960	acyl-CoA dehydrogenase activity
EYD00_16180	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYD00_16195	COG1024	Enoyl-CoA hydratase
EYD00_16200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYD00_16205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EYD00_16210	COG4952	isomerase
EYD00_16215	COG3347	Dehydrogenase
EYD00_16215	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_16220	COG1349	DNA-binding transcription factor activity
EYD00_16235	COG1129	ABC transporter
EYD00_16240	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_16245	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_16250	COG3254	rhamnose metabolic process
EYD00_16265	COG2264	protein methyltransferase activity
EYD00_16270	COG5001	Diguanylate cyclase
EYD00_16285	COG4335	DNA alkylation repair
EYD00_16290	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYD00_16295	COG4208	sulfate ABC transporter
EYD00_16310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EYD00_16325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EYD00_16335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYD00_16345	COG1040	competence protein
EYD00_16350	COG2226	methyltransferase
EYD00_16365	COG0494	nUDIX hydrolase
EYD00_16370	COG0456	acetyltransferase
EYD00_16375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYD00_16380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EYD00_16385	COG0653	protein targeting
EYD00_16390	COG0697	spore germination
EYD00_16450	COG1215	transferase activity, transferring glycosyl groups
EYD00_16455	COG2244	polysaccharide biosynthetic process
EYD00_16475	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYD00_16485	COG0489	protein tyrosine kinase activity
EYD00_16485	COG3206	protein involved in exopolysaccharide biosynthesis
EYD00_16500	COG0297	glycogen (starch) synthase activity
EYD00_16505	COG0438	transferase activity, transferring glycosyl groups
EYD00_16510	COG0438	transferase activity, transferring glycosyl groups
EYD00_16530	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EYD00_16530	COG2273	Hydrolase Family 16
EYD00_16575	COG1396	sequence-specific DNA binding
EYD00_16585	COG1129	ABC transporter
EYD00_16590	COG4214	carbohydrate transport
EYD00_16595	COG4213	ABC transporter substrate-binding protein
EYD00_16625	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EYD00_16635	COG0625	glutathione transferase activity
EYD00_16640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYD00_16645	COG1396	sequence-specific DNA binding
EYD00_16645	COG3800	Transcriptional regulator
EYD00_16655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYD00_16665	COG0300	oxidoreductase activity
EYD00_16675	COG2096	Adenosyltransferase
EYD00_16685	COG2086	electron transfer activity
EYD00_16695	COG1250	3-hydroxyacyl-CoA dehydrogenase
EYD00_16700	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EYD00_16705	COG0165	Argininosuccinate lyase
EYD00_16740	COG2884	Cell division ATP-binding protein ftsE
EYD00_16760	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EYD00_16770	COG0287	Prephenate dehydrogenase
EYD00_16775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYD00_16780	COG2226	methyltransferase
EYD00_16785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYD00_16800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYD00_16805	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EYD00_16840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYD00_16845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYD00_16860	COG4974	Belongs to the 'phage' integrase family
EYD00_16865	COG0825	malonyl-CoA metabolic process
EYD00_16870	COG3034	peptidoglycan biosynthetic process
EYD00_16875	COG0425	Belongs to the sulfur carrier protein TusA family
EYD00_16875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYD00_16880	COG0523	cobalamin synthesis protein
EYD00_16885	COG1686	Belongs to the peptidase S11 family
EYD00_16890	COG1473	amidohydrolase
EYD00_16900	COG4953	penicillin-binding protein 1C
EYD00_16905	COG2373	Large extracellular alpha-helical protein
EYD00_16910	COG2835	tetraacyldisaccharide 4'-kinase activity
EYD00_16945	COG0482	sulfurtransferase activity
EYD00_16960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYD00_16975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYD00_16980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYD00_16985	COG0037	tRNA processing
EYD00_16995	COG2885	chlorophyll binding
EYD00_17000	COG0823	Involved in the tonB-independent uptake of proteins
EYD00_17020	COG0824	Thioesterase
EYD00_17030	COG0494	nUDIX hydrolase
EYD00_17045	COG2255	four-way junction helicase activity
EYD00_17050	COG0632	four-way junction helicase activity
EYD00_17055	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EYD00_17060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_17065	COG0217	transcriptional regulatory protein
EYD00_17080	COG1692	metallophosphoesterase
EYD00_17085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYD00_17090	COG1253	flavin adenine dinucleotide binding
EYD00_17130	COG0126	phosphoglycerate kinase activity
EYD00_17135	COG3588	fructose-bisphosphate aldolase
EYD00_17155	COG0254	rRNA binding
EYD00_17160	COG1132	(ABC) transporter
EYD00_17180	COG0483	inositol monophosphate 1-phosphatase activity
EYD00_17210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYD00_17215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EYD00_17220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYD00_17225	COG0457	Tetratricopeptide repeat
EYD00_17230	COG3750	Belongs to the UPF0335 family
EYD00_17250	COG0469	pyruvate kinase activity
EYD00_17255	COG3108	Peptidase M15
EYD00_17260	COG2204	response regulator
EYD00_17265	COG1164	Oligoendopeptidase f
EYD00_17270	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYD00_17275	COG3706	GGDEF domain
EYD00_17275	COG0745	RESPONSE REGULATOR receiver
EYD00_17280	COG5310	Homospermidine synthase
EYD00_17290	COG0737	Belongs to the 5'-nucleotidase family
EYD00_17295	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EYD00_17300	COG0330	HflC and HflK could
EYD00_17325	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYD00_17330	COG2951	lytic endotransglycosylase activity
EYD00_17345	COG2205	protein histidine kinase activity
EYD00_17355	COG0067	glutamate synthase
EYD00_17355	COG0069	glutamate synthase activity
EYD00_17355	COG0070	glutamate synthase
EYD00_17370	COG2205	protein histidine kinase activity
EYD00_17375	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EYD00_17380	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EYD00_17385	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EYD00_17395	COG0252	asparaginase activity
EYD00_17405	COG1027	Aspartate ammonia-lyase
EYD00_17410	COG2186	Transcriptional regulator
EYD00_17425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_17430	COG1309	transcriptional regulator
EYD00_17435	COG1609	Transcriptional regulator
EYD00_17440	COG0673	inositol 2-dehydrogenase activity
EYD00_17455	COG1175	transmembrane transport
EYD00_17460	COG0395	ABC-type sugar transport system, permease component
EYD00_17465	COG3842	ATPase activity
EYD00_17470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_17485	COG2828	Protein conserved in bacteria
EYD00_17490	COG0583	DNA-binding transcription factor activity
EYD00_17505	COG1522	sequence-specific DNA binding
EYD00_17525	COG0395	ABC-type sugar transport system, permease component
EYD00_17535	COG1215	transferase activity, transferring glycosyl groups
EYD00_17545	COG2204	response regulator
EYD00_17550	COG0745	RESPONSE REGULATOR receiver
EYD00_17555	COG0784	Response regulator, receiver
EYD00_17555	COG2205	protein histidine kinase activity
EYD00_17560	COG0784	Response regulator, receiver
EYD00_17565	COG3920	Histidine kinase
EYD00_17565	COG2202	Pas domain
EYD00_17570	COG0784	Response regulator, receiver
EYD00_17575	COG4251	negative regulation of phosphorylation
EYD00_17600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYD00_17635	COG3920	Histidine kinase
EYD00_17665	COG0405	Gamma-glutamyltransferase
EYD00_17670	COG1309	transcriptional regulator
EYD00_17675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYD00_17680	COG2080	2 iron, 2 sulfur cluster binding
EYD00_17685	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYD00_17690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYD00_17695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYD00_17705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYD00_17710	COG0583	DNA-binding transcription factor activity
EYD00_17720	COG0667	Aldo Keto reductase
EYD00_17725	COG2972	Histidine kinase
EYD00_17725	COG0840	transmembrane signaling receptor activity
EYD00_17735	COG2985	domain, Protein
EYD00_17745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYD00_17760	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_17770	COG3842	ATPase activity
EYD00_17775	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYD00_17780	COG1177	transmembrane transport
EYD00_17785	COG1335	isochorismatase
EYD00_17790	COG1349	DNA-binding transcription factor activity
EYD00_17800	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYD00_17830	COG0534	Mate efflux family protein
EYD00_17850	COG2072	flavoprotein involved in K transport
EYD00_17855	COG3842	ATPase activity
EYD00_17860	COG1177	transmembrane transport
EYD00_17865	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYD00_17875	COG0583	DNA-binding transcription factor activity
EYD00_17885	COG3706	GGDEF domain
EYD00_17890	COG3284	Transcriptional regulator
EYD00_17895	COG1063	alcohol dehydrogenase
EYD00_17920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EYD00_17940	COG4774	siderophore transport
EYD00_17950	COG1120	ATPase activity
EYD00_17985	COG2207	Transcriptional regulator
EYD00_17995	COG0583	DNA-binding transcription factor activity
EYD00_18020	COG0583	DNA-binding transcription factor activity
EYD00_18060	COG4608	Belongs to the ABC transporter superfamily
EYD00_18070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_18075	COG0601	transmembrane transport
EYD00_18080	COG0747	negative chemotaxis
EYD00_18090	COG0784	Response regulator, receiver
EYD00_18090	COG4191	Histidine kinase
EYD00_18095	COG0784	Response regulator, receiver
EYD00_18100	COG2202	Pas domain
EYD00_18100	COG3920	Histidine kinase
EYD00_18125	COG2197	response regulator
EYD00_18165	COG0583	DNA-binding transcription factor activity
EYD00_18170	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_18175	COG0840	transmembrane signaling receptor activity
EYD00_18180	COG3706	GGDEF domain
EYD00_18200	COG1846	Transcriptional regulator
EYD00_18215	COG0583	DNA-binding transcription factor activity
EYD00_18220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYD00_18240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYD00_18245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYD00_18250	COG0583	DNA-binding transcription factor activity
EYD00_18265	COG1802	Transcriptional regulator
EYD00_18270	COG3842	ATPase activity
EYD00_18275	COG4209	transmembrane transport
EYD00_18280	COG0395	ABC-type sugar transport system, permease component
EYD00_18285	COG1653	transport
EYD00_18295	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_18305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYD00_18315	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_18325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYD00_18330	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYD00_18335	COG2080	2 iron, 2 sulfur cluster binding
EYD00_18345	COG1082	Xylose isomerase domain protein TIM barrel
EYD00_18350	COG0572	uridine kinase
EYD00_18355	COG1082	Xylose isomerase domain protein TIM barrel
EYD00_18360	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_18365	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_18415	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_18420	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_18425	COG2207	Transcriptional regulator
EYD00_18480	COG0402	S-adenosylhomocysteine deaminase activity
EYD00_18485	COG1228	amidohydrolase
EYD00_18490	COG2986	histidine ammonia-lyase
EYD00_18500	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EYD00_18535	COG1192	Involved in chromosome partitioning
EYD00_18540	COG1475	DNA binding
EYD00_18545	COG1414	Transcriptional regulator
EYD00_18570	COG4771	TonB-dependent receptor
EYD00_18575	COG0789	Transcriptional regulator
EYD00_18580	COG0366	Alpha amylase catalytic
EYD00_18585	COG4770	biotin carboxylase activity
EYD00_18590	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYD00_18595	COG4336	lyase activity
EYD00_18600	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EYD00_18605	COG1914	H( )-stimulated, divalent metal cation uptake system
EYD00_18610	COG1802	Transcriptional regulator
EYD00_18615	COG3707	response regulator
EYD00_18620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_18625	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_18630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_18635	COG1116	anion transmembrane transporter activity
EYD00_18640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EYD00_18655	COG0243	molybdopterin cofactor binding
EYD00_18660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EYD00_18660	COG1648	precorrin-2 dehydrogenase activity
EYD00_18680	COG3842	ATPase activity
EYD00_18690	COG0395	ABC-type sugar transport system, permease component
EYD00_18705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYD00_18720	COG0071	Belongs to the small heat shock protein (HSP20) family
EYD00_18755	COG1129	ABC transporter
EYD00_18770	COG0667	Aldo Keto reductase
EYD00_18775	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EYD00_18780	COG1830	Aldolase
EYD00_18785	COG1070	Carbohydrate kinase
EYD00_18790	COG1846	Transcriptional regulator
EYD00_18800	COG1304	FMN binding
EYD00_18805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYD00_18810	COG0488	(ABC) transporter
EYD00_18825	COG2308	Evidence 4 Homologs of previously reported genes of
EYD00_18825	COG2307	Protein conserved in bacteria
EYD00_18850	COG1607	acyl-coa hydrolase
EYD00_18865	COG2186	Transcriptional regulator
EYD00_18870	COG1454	alcohol dehydrogenase
EYD00_18875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EYD00_18890	COG0747	negative chemotaxis
EYD00_18895	COG0601	transmembrane transport
EYD00_18910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_18940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYD00_18970	COG4172	Belongs to the ABC transporter superfamily
EYD00_18975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_18980	COG0601	transmembrane transport
EYD00_18985	COG4166	transmembrane transport
EYD00_18990	COG3300	MHYT domain
EYD00_18990	COG5001	Diguanylate cyclase
EYD00_19000	COG1215	transferase activity, transferring glycosyl groups
EYD00_19015	COG0598	Magnesium transport protein CorA
EYD00_19020	COG4529	Protein conserved in bacteria
EYD00_19045	COG0747	negative chemotaxis
EYD00_19050	COG0601	transmembrane transport
EYD00_19055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_19070	COG1473	amidohydrolase
EYD00_19080	COG0154	amidase activity
EYD00_19095	COG0673	inositol 2-dehydrogenase activity
EYD00_19100	COG1082	Xylose isomerase domain protein TIM barrel
EYD00_19110	COG1609	Transcriptional regulator
EYD00_19115	COG1126	abc transporter atp-binding protein
EYD00_19120	COG0765	amino acid transport
EYD00_19125	COG0765	amino acid transport
EYD00_19130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_19135	COG3608	succinylglutamate desuccinylase aspartoacylase
EYD00_19140	COG0006	proline dipeptidase activity
EYD00_19145	COG2423	ornithine cyclodeaminase activity
EYD00_19150	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYD00_19155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYD00_19160	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYD00_19165	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_19170	COG1522	sequence-specific DNA binding
EYD00_19185	COG0583	DNA-binding transcription factor activity
EYD00_19190	COG0346	lactoylglutathione lyase activity
EYD00_19205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EYD00_19225	COG0583	DNA-binding transcription factor activity
EYD00_19230	COG0477	Major facilitator Superfamily
EYD00_19235	COG3850	Histidine kinase
EYD00_19235	COG5002	protein histidine kinase activity
EYD00_19240	COG0745	RESPONSE REGULATOR receiver
EYD00_19245	COG0671	phosphoesterase, PA-phosphatase related
EYD00_19280	COG0456	acetyltransferase
EYD00_19285	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYD00_19295	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EYD00_19300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYD00_19305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYD00_19345	COG0697	spore germination
EYD00_19350	COG0673	inositol 2-dehydrogenase activity
EYD00_19375	COG0477	Major facilitator Superfamily
EYD00_19380	COG0642	Histidine kinase
EYD00_19385	COG0745	RESPONSE REGULATOR receiver
EYD00_19390	COG2194	sulfuric ester hydrolase activity
EYD00_19400	COG0583	DNA-binding transcription factor activity
EYD00_19405	COG4774	siderophore transport
EYD00_19420	COG1120	ATPase activity
EYD00_19435	COG2137	regulation of response to DNA damage stimulus
EYD00_19440	COG3386	PFAM SMP-30 Gluconolaconase
EYD00_19450	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_19455	COG1129	ABC transporter
EYD00_19460	COG1879	ABC-type sugar transport system periplasmic component
EYD00_19470	COG4585	Histidine kinase
EYD00_19475	COG2197	response regulator
EYD00_19485	COG2133	pyrroloquinoline quinone binding
EYD00_19495	COG0500	methyltransferase
EYD00_19515	COG4175	Glycine betaine
EYD00_19515	COG3448	diguanylate cyclase activity
EYD00_19520	COG4176	ABC-type proline glycine betaine transport system permease component
EYD00_19530	COG4191	Histidine kinase
EYD00_19530	COG0784	Response regulator, receiver
EYD00_19540	COG0489	protein tyrosine kinase activity
EYD00_19540	COG3206	protein involved in exopolysaccharide biosynthesis
EYD00_19545	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EYD00_19550	COG1215	transferase activity, transferring glycosyl groups
EYD00_19555	COG1215	transferase activity, transferring glycosyl groups
EYD00_19560	COG1215	transferase activity, transferring glycosyl groups
EYD00_19565	COG0438	transferase activity, transferring glycosyl groups
EYD00_19570	COG2273	Hydrolase Family 16
EYD00_19575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EYD00_19580	COG2244	polysaccharide biosynthetic process
EYD00_19585	COG0463	Glycosyl transferase, family 2
EYD00_19590	COG2327	Polysaccharide pyruvyl transferase
EYD00_19595	COG1215	transferase activity, transferring glycosyl groups
EYD00_19615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYD00_19625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_19640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EYD00_19640	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYD00_19660	COG1523	belongs to the glycosyl hydrolase 13 family
EYD00_19665	COG0033	Phosphoglucomutase
EYD00_19670	COG0297	glycogen (starch) synthase activity
EYD00_19675	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYD00_19680	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYD00_19685	COG0058	SHG alpha-glucan phosphorylase activity
EYD00_19700	COG1794	racemase activity, acting on amino acids and derivatives
EYD00_19705	COG1522	sequence-specific DNA binding
EYD00_19715	COG2084	Dehydrogenase
EYD00_19720	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_19725	COG1063	alcohol dehydrogenase
EYD00_19735	COG4988	ABC transporter
EYD00_19740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EYD00_19750	COG1294	oxidase, subunit
EYD00_19780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EYD00_19785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYD00_19815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYD00_19820	COG0539	negative regulation of cytoplasmic translation
EYD00_19850	COG4221	oxidoreductase activity
EYD00_19865	COG0747	negative chemotaxis
EYD00_19870	COG0601	transmembrane transport
EYD00_19875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_19880	COG0444	Belongs to the ABC transporter superfamily
EYD00_19885	COG4608	Belongs to the ABC transporter superfamily
EYD00_19890	COG0246	Mannitol dehydrogenase
EYD00_19905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_19925	COG0410	ABC transporter
EYD00_19930	COG0559	Belongs to the binding-protein-dependent transport system permease family
EYD00_19950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EYD00_19955	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_19965	COG4993	Dehydrogenase
EYD00_19970	COG3685	Protein conserved in bacteria
EYD00_19975	COG1285	pathogenesis
EYD00_20000	COG0693	protein deglycase activity
EYD00_20025	COG0189	ligase activity
EYD00_20030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYD00_20035	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EYD00_20045	COG0583	DNA-binding transcription factor activity
EYD00_20050	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_20055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_20060	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_20065	COG1116	anion transmembrane transporter activity
EYD00_20075	COG1522	sequence-specific DNA binding
EYD00_20090	COG0784	Response regulator, receiver
EYD00_20110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYD00_20125	COG0019	diaminopimelate decarboxylase activity
EYD00_20145	COG0527	aspartate kinase activity
EYD00_20155	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYD00_20160	COG2890	protein-(glutamine-N5) methyltransferase activity
EYD00_20170	COG0542	response to heat
EYD00_20175	COG0739	heme binding
EYD00_20175	COG0741	lytic transglycosylase activity
EYD00_20175	COG1196	nuclear chromosome segregation
EYD00_20230	COG3842	ATPase activity
EYD00_20235	COG1063	alcohol dehydrogenase
EYD00_20240	COG0395	ABC-type sugar transport system, permease component
EYD00_20295	COG4221	oxidoreductase activity
EYD00_20305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EYD00_20345	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EYD00_20375	COG2986	histidine ammonia-lyase
EYD00_20400	COG1125	glycine betaine transport
EYD00_20400	COG0517	IMP dehydrogenase activity
EYD00_20420	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_20435	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EYD00_20440	COG0583	DNA-binding transcription factor activity
EYD00_20445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EYD00_20455	COG3734	2-keto-3-deoxy-galactonokinase
EYD00_20460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_20465	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_20475	COG1175	transmembrane transport
EYD00_20480	COG0395	ABC-type sugar transport system, permease component
EYD00_20485	COG3842	ATPase activity
EYD00_20495	COG1414	Transcriptional regulator
EYD00_20500	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_20510	COG1309	transcriptional regulator
EYD00_20520	COG0745	RESPONSE REGULATOR receiver
EYD00_20525	COG1840	ABC-type Fe3 transport system, periplasmic component
EYD00_20530	COG1840	ABC-type Fe3 transport system, periplasmic component
EYD00_20540	COG3842	ATPase activity
EYD00_20545	COG1063	alcohol dehydrogenase
EYD00_20555	COG1879	ABC-type sugar transport system periplasmic component
EYD00_20565	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_20585	COG0477	Major facilitator Superfamily
EYD00_20620	COG1178	ABC-type Fe3 transport system permease component
EYD00_20625	COG3842	ATPase activity
EYD00_20655	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_20660	COG0473	3-isopropylmalate dehydrogenase activity
EYD00_20665	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_20675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYD00_20680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYD00_20695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_20700	COG1120	ATPase activity
EYD00_20710	COG2226	methyltransferase
EYD00_20725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_20730	COG1120	ATPase activity
EYD00_20740	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
EYD00_20745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_20765	COG0673	inositol 2-dehydrogenase activity
EYD00_20770	COG0673	inositol 2-dehydrogenase activity
EYD00_20780	COG1175	transmembrane transport
EYD00_20785	COG0395	ABC-type sugar transport system, permease component
EYD00_20800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYD00_20805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYD00_20810	COG2197	response regulator
EYD00_20815	COG0601	transmembrane transport
EYD00_20825	COG4172	Belongs to the ABC transporter superfamily
EYD00_20840	COG0747	negative chemotaxis
EYD00_20855	COG1446	asparaginase
EYD00_20860	COG0583	DNA-binding transcription factor activity
EYD00_20865	COG0601	transmembrane transport
EYD00_20875	COG4172	Belongs to the ABC transporter superfamily
EYD00_20890	COG1473	amidohydrolase
EYD00_20905	COG1129	ABC transporter
EYD00_20910	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_20915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EYD00_20920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EYD00_20930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EYD00_20950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_20965	COG2079	MmgE PrpD family protein
EYD00_20975	COG0765	amino acid transport
EYD00_20990	COG0281	malic enzyme
EYD00_20990	COG0280	phosphate acetyltransferase
EYD00_20995	COG0583	DNA-binding transcription factor activity
EYD00_21030	COG0395	ABC-type sugar transport system, permease component
EYD00_21050	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYD00_21055	COG0720	synthase
EYD00_21060	COG0602	queuosine metabolic process
EYD00_21065	COG0673	inositol 2-dehydrogenase activity
EYD00_21075	COG3842	ATPase activity
EYD00_21090	COG1653	transport
EYD00_21095	COG1609	Transcriptional regulator
EYD00_21110	COG2094	Belongs to the DNA glycosylase MPG family
EYD00_21120	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_21130	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_21155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_21160	COG4215	(ABC) transporter
EYD00_21170	COG1410	methionine synthase
EYD00_21170	COG0646	methionine synthase
EYD00_21185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYD00_21190	COG1596	polysaccharide export
EYD00_21195	COG3307	-O-antigen
EYD00_21225	COG2197	response regulator
EYD00_21260	COG2942	2-epimerase
EYD00_21270	COG1215	transferase activity, transferring glycosyl groups
EYD00_21300	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_21305	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EYD00_21315	COG1301	dicarboxylic acid transport
EYD00_21320	COG4191	Histidine kinase
EYD00_21325	COG2204	response regulator
EYD00_21340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_21345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYD00_21350	COG1522	sequence-specific DNA binding
EYD00_21355	COG0351	phosphomethylpyrimidine kinase
EYD00_21360	COG0352	thiamine-phosphate diphosphorylase activity
EYD00_21365	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EYD00_21370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYD00_21375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYD00_21380	COG1501	Belongs to the glycosyl hydrolase 31 family
EYD00_21385	COG0395	ABC-type sugar transport system, permease component
EYD00_21390	COG1175	transmembrane transport
EYD00_21395	COG1653	transport
EYD00_21400	COG3842	ATPase activity
EYD00_21415	COG4989	oxidoreductase activity
EYD00_21450	COG0438	transferase activity, transferring glycosyl groups
EYD00_21455	COG0747	negative chemotaxis
EYD00_21460	COG0601	transmembrane transport
EYD00_21470	COG3964	amidohydrolase
EYD00_21485	COG1921	L-seryl-tRNASec selenium transferase activity
EYD00_21495	COG0625	glutathione transferase activity
EYD00_21500	COG0640	Transcriptional regulator
EYD00_21510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EYD00_21515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYD00_21520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_21535	COG1312	Catalyzes the dehydration of D-mannonate
EYD00_21540	COG1063	alcohol dehydrogenase
EYD00_21545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYD00_21555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_21560	COG2186	Transcriptional regulator
EYD00_21565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EYD00_21570	COG0850	regulation of cytokinetic process
EYD00_21575	COG2894	cell division
EYD00_21580	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYD00_21590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_21595	COG5001	Diguanylate cyclase
EYD00_21630	COG0673	inositol 2-dehydrogenase activity
EYD00_21640	COG1653	transport
EYD00_21645	COG1175	transmembrane transport
EYD00_21650	COG0395	ABC-type sugar transport system, permease component
EYD00_21655	COG3842	ATPase activity
EYD00_21665	COG0673	inositol 2-dehydrogenase activity
EYD00_21695	COG2186	Transcriptional regulator
EYD00_21700	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_21705	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYD00_21710	COG1129	ABC transporter
EYD00_21715	COG1879	ABC-type sugar transport system periplasmic component
EYD00_21720	COG0129	dihydroxy-acid dehydratase activity
EYD00_21730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYD00_21735	COG4608	Belongs to the ABC transporter superfamily
EYD00_21740	COG0444	Belongs to the ABC transporter superfamily
EYD00_21745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_21750	COG0601	transmembrane transport
EYD00_21755	COG0747	negative chemotaxis
EYD00_21765	COG0395	ABC-type sugar transport system, permease component
EYD00_21770	COG1175	transmembrane transport
EYD00_21775	COG3842	ATPase activity
EYD00_21785	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EYD00_21805	COG2814	Major facilitator Superfamily
EYD00_21810	COG4774	siderophore transport
EYD00_21815	COG3712	iron ion homeostasis
EYD00_21825	COG1940	carbohydrate kinase activity
EYD00_21830	COG0584	glycerophosphoryl diester phosphodiesterase
EYD00_21835	COG0300	oxidoreductase activity
EYD00_21845	COG1846	Transcriptional regulator
EYD00_21845	COG1940	carbohydrate kinase activity
EYD00_21855	COG3842	ATPase activity
EYD00_21860	COG1177	transmembrane transport
EYD00_21920	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_21925	COG1368	sulfuric ester hydrolase activity
EYD00_21990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYD00_22000	COG3436	PFAM IS66 Orf2 family protein
EYD00_22005	COG4372	Transposase
EYD00_22010	COG3012	SEC-C Motif Domain Protein
EYD00_22020	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EYD00_22055	COG0385	Bile acid
EYD00_22060	COG0667	Aldo Keto reductase
EYD00_22065	COG0583	DNA-binding transcription factor activity
EYD00_22075	COG1132	(ABC) transporter
EYD00_22085	COG0438	transferase activity, transferring glycosyl groups
EYD00_22090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EYD00_22090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EYD00_22095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EYD00_22100	COG2942	2-epimerase
EYD00_22115	COG2963	transposase activity
EYD00_22120	COG3436	PFAM IS66 Orf2 family protein
EYD00_22125	COG4372	Transposase
EYD00_22130	COG3547	Transposase (IS116 IS110 IS902 family)
EYD00_22165	COG3436	PFAM IS66 Orf2 family protein
EYD00_22170	COG2963	transposase activity
EYD00_22190	COG1484	DNA-dependent DNA replication
EYD00_22195	COG4584	PFAM Integrase catalytic
EYD00_22200	COG2801	Transposase and inactivated derivatives
EYD00_22235	COG0210	DNA helicase
EYD00_22245	COG1609	Transcriptional regulator
EYD00_22250	COG1233	COG1233 Phytoene dehydrogenase and related
EYD00_22265	COG0395	ABC-type sugar transport system, permease component
EYD00_22270	COG3842	ATPase activity
EYD00_22275	COG4608	Belongs to the ABC transporter superfamily
EYD00_22280	COG0444	Belongs to the ABC transporter superfamily
EYD00_22290	COG0601	transmembrane transport
EYD00_22295	COG2186	Transcriptional regulator
EYD00_22305	COG0747	negative chemotaxis
EYD00_22315	COG5001	Diguanylate cyclase
EYD00_22315	COG3300	MHYT domain
EYD00_22320	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_22330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EYD00_22340	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EYD00_22345	COG0306	phosphate transporter
EYD00_22350	COG1392	Phosphate transport regulator
EYD00_22365	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EYD00_22375	COG2207	Transcriptional regulator
EYD00_22380	COG4774	siderophore transport
EYD00_22390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_22395	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYD00_22400	COG1120	ATPase activity
EYD00_22445	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_22460	COG3119	arylsulfatase activity
EYD00_22465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_22470	COG3842	ATPase activity
EYD00_22475	COG0165	Argininosuccinate lyase
EYD00_22480	COG0395	ABC-type sugar transport system, permease component
EYD00_22485	COG1175	transmembrane transport
EYD00_22490	COG2182	Extracellular solute-binding protein
EYD00_22495	COG1940	carbohydrate kinase activity
EYD00_22520	COG1486	melibiose metabolic process
EYD00_22525	COG0747	negative chemotaxis
EYD00_22530	COG0601	transmembrane transport
EYD00_22535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_22540	COG4172	Belongs to the ABC transporter superfamily
EYD00_22545	COG1486	melibiose metabolic process
EYD00_22555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_22560	COG1129	ABC transporter
EYD00_22560	COG0842	Transport permease protein
EYD00_22565	COG0842	Transport permease protein
EYD00_22580	COG0784	Response regulator, receiver
EYD00_22585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYD00_22595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_22600	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYD00_22620	COG0765	amino acid transport
EYD00_22630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EYD00_22640	COG3938	Belongs to the proline racemase family
EYD00_22655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_22665	COG0765	amino acid transport
EYD00_22675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYD00_22690	COG0402	S-adenosylhomocysteine deaminase activity
EYD00_22705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_22715	COG1228	amidohydrolase
EYD00_22720	COG0444	Belongs to the ABC transporter superfamily
EYD00_22725	COG4608	Belongs to the ABC transporter superfamily
EYD00_22730	COG1802	Transcriptional regulator
EYD00_22735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYD00_22760	COG3383	formate dehydrogenase (NAD+) activity
EYD00_22775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYD00_22790	COG0747	negative chemotaxis
EYD00_22795	COG0601	transmembrane transport
EYD00_22800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_22805	COG4172	Belongs to the ABC transporter superfamily
EYD00_22810	COG4948	Mandelate Racemase Muconate Lactonizing
EYD00_22820	COG2186	Transcriptional regulator
EYD00_22825	COG0747	negative chemotaxis
EYD00_22830	COG0601	transmembrane transport
EYD00_22840	COG0405	Gamma-glutamyltransferase
EYD00_22850	COG0483	inositol monophosphate 1-phosphatase activity
EYD00_22860	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYD00_22880	COG3237	CsbD-like
EYD00_22890	COG0655	NAD(P)H dehydrogenase (quinone) activity
EYD00_22905	COG0753	catalase activity
EYD00_22925	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_22935	COG0243	molybdopterin cofactor binding
EYD00_22950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EYD00_22975	COG2010	Cytochrome c
EYD00_23005	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYD00_23015	COG0297	glycogen (starch) synthase activity
EYD00_23040	COG3685	Protein conserved in bacteria
EYD00_23095	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EYD00_23100	COG3181	Tripartite tricarboxylate transporter family receptor
EYD00_23105	COG5265	(ABC) transporter
EYD00_23135	COG2140	Oxalate decarboxylase
EYD00_23150	COG4566	intracellular signal transduction
EYD00_23160	COG0243	molybdopterin cofactor binding
EYD00_23165	COG0783	Belongs to the Dps family
EYD00_23185	COG0596	Alpha beta hydrolase
EYD00_23195	COG1764	response to oxidative stress
EYD00_23200	COG2205	protein histidine kinase activity
EYD00_23205	COG0745	RESPONSE REGULATOR receiver
EYD00_23235	COG4178	(ABC) transporter
EYD00_23245	COG0025	NhaP-type Na H and K H
EYD00_23250	COG2130	NADP-dependent
EYD00_23255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYD00_23275	COG0406	alpha-ribazole phosphatase activity
EYD00_23290	COG1475	DNA binding
EYD00_23295	COG0640	Transcriptional regulator
EYD00_23320	COG0431	NADPH-dependent FMN reductase
EYD00_23330	COG0798	PFAM Bile acid sodium symporter
EYD00_23345	COG0640	Transcriptional regulator
EYD00_23405	COG5290	Psort location Cytoplasmic, score
EYD00_23440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYD00_23470	COG0765	amino acid transport
EYD00_23480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYD00_23490	COG1940	carbohydrate kinase activity
EYD00_23490	COG1846	Transcriptional regulator
EYD00_23505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYD00_23515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EYD00_23525	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYD00_23535	COG1082	Xylose isomerase domain protein TIM barrel
EYD00_23540	COG0252	asparaginase activity
EYD00_23550	COG1126	abc transporter atp-binding protein
EYD00_23560	COG0765	amino acid transport
EYD00_23565	COG0765	amino acid transport
EYD00_23575	COG0165	Argininosuccinate lyase
EYD00_23585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYD00_23590	COG0583	DNA-binding transcription factor activity
EYD00_23600	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYD00_23615	COG1959	2 iron, 2 sulfur cluster binding
EYD00_23625	COG2169	Transcriptional regulator
EYD00_23625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYD00_23660	COG5489	Protein of unknown function (DUF736)
EYD00_23665	COG0776	regulation of translation
EYD00_23670	COG3831	ATPase activity
EYD00_23725	COG0251	oxidation-reduction process
EYD00_23780	COG3436	PFAM IS66 Orf2 family protein
EYD00_23785	COG4372	Transposase
EYD00_23800	COG0747	negative chemotaxis
EYD00_23805	COG0601	transmembrane transport
EYD00_23810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_23825	COG1473	amidohydrolase
EYD00_23840	COG2207	Transcriptional regulator
EYD00_23855	COG2080	2 iron, 2 sulfur cluster binding
EYD00_23860	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EYD00_23865	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYD00_23885	COG1063	alcohol dehydrogenase
EYD00_23890	COG0156	8-amino-7-oxononanoate synthase activity
EYD00_23900	COG1396	sequence-specific DNA binding
EYD00_23925	COG1755	Isoprenylcysteine carboxyl methyltransferase
EYD00_23930	COG0783	Belongs to the Dps family
EYD00_23955	COG1733	regulation of RNA biosynthetic process
EYD00_23970	COG4644	lycopene metabolic process
EYD00_23980	COG2072	flavoprotein involved in K transport
EYD00_23990	COG2144	transferase activity, transferring acyl groups
EYD00_24015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYD00_24050	COG1741	Belongs to the pirin family
EYD00_24055	COG1335	isochorismatase
EYD00_24060	COG0583	DNA-binding transcription factor activity
EYD00_24065	COG1733	regulation of RNA biosynthetic process
EYD00_24070	COG0604	alcohol dehydrogenase
EYD00_24075	COG1012	belongs to the aldehyde dehydrogenase family
EYD00_24080	COG0583	DNA-binding transcription factor activity
EYD00_24090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYD00_24110	COG1275	C4-dicarboxylate transporter malic acid transport protein
EYD00_24130	COG0625	glutathione transferase activity
EYD00_24135	COG1017	nitric oxide dioxygenase activity
EYD00_24135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EYD00_24145	COG0583	DNA-binding transcription factor activity
EYD00_24160	COG1335	isochorismatase
EYD00_24205	COG3842	ATPase activity
EYD00_24230	COG3620	sequence-specific DNA binding
EYD00_24235	COG3550	peptidyl-serine autophosphorylation
EYD00_24240	COG3077	Addiction module antitoxin, RelB DinJ family
EYD00_24250	COG0840	transmembrane signaling receptor activity
EYD00_24290	COG1609	Transcriptional regulator
EYD00_24295	COG0747	negative chemotaxis
EYD00_24305	COG0601	transmembrane transport
EYD00_24310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_24320	COG3622	Belongs to the hyi family
EYD00_24325	COG2084	Dehydrogenase
EYD00_24335	COG4423	Transcription factor
EYD00_24340	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
EYD00_24365	COG1309	transcriptional regulator
EYD00_24405	COG0668	transmembrane transport
EYD00_24415	COG1959	2 iron, 2 sulfur cluster binding
EYD00_24420	COG4566	intracellular signal transduction
EYD00_24445	COG0668	transmembrane transport
EYD00_24450	COG4191	Histidine kinase
EYD00_24455	COG2204	response regulator
EYD00_24460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYD00_24465	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_24480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYD00_24515	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
EYD00_24565	COG4456	Virulence-associated protein
EYD00_24605	COG0714	Associated with various cellular activities
EYD00_24610	COG3256	nitric oxide reductase
EYD00_24625	COG1845	cytochrome c oxidase, subunit III
EYD00_24645	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYD00_24695	COG4459	periplasmic nitrate reductase
EYD00_24710	COG0243	molybdopterin cofactor binding
EYD00_24720	COG3005	denitrification pathway
EYD00_24745	COG2354	Protein conserved in bacteria
EYD00_24750	COG0598	Magnesium transport protein CorA
EYD00_24760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYD00_24765	COG0587	DNA-directed DNA polymerase activity
EYD00_24780	COG0583	DNA-binding transcription factor activity
EYD00_24795	COG1309	transcriptional regulator
EYD00_24800	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_24815	COG4221	oxidoreductase activity
EYD00_24825	COG4221	oxidoreductase activity
EYD00_24830	COG1959	2 iron, 2 sulfur cluster binding
EYD00_24865	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_24870	COG1733	regulation of RNA biosynthetic process
EYD00_24880	COG0477	Major facilitator Superfamily
EYD00_24890	COG1794	racemase activity, acting on amino acids and derivatives
EYD00_24900	COG0300	oxidoreductase activity
EYD00_24915	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EYD00_24920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EYD00_24930	COG1605	Chorismate mutase
EYD00_24930	COG0287	Prephenate dehydrogenase
EYD00_24935	COG0583	DNA-binding transcription factor activity
EYD00_24940	COG0300	oxidoreductase activity
EYD00_24955	COG1376	ErfK ybiS ycfS ynhG family protein
EYD00_24965	COG1280	lysine exporter protein (LysE YggA)
EYD00_24970	COG0251	oxidation-reduction process
EYD00_24980	COG1278	Cold shock
EYD00_25065	COG0395	ABC-type sugar transport system, permease component
EYD00_25080	COG1737	Transcriptional regulator
EYD00_25105	COG2814	Major facilitator Superfamily
EYD00_25155	COG1487	ribonuclease activity
EYD00_25160	COG4691	Plasmid stability protein
EYD00_25190	COG0776	regulation of translation
EYD00_25215	COG2197	response regulator
EYD00_25220	COG4585	Histidine kinase
EYD00_25235	COG0659	secondary active sulfate transmembrane transporter activity
EYD00_25245	COG1280	lysine exporter protein (LysE YggA)
EYD00_25260	COG5425	PFAM Usg family protein
EYD00_25265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYD00_25270	COG0459	protein refolding
EYD00_25280	COG4172	Belongs to the ABC transporter superfamily
EYD00_25285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_25290	COG0601	transmembrane transport
EYD00_25310	COG0025	NhaP-type Na H and K H
EYD00_25320	COG0243	molybdopterin cofactor binding
EYD00_25330	COG2116	formate transmembrane transporter activity
EYD00_25335	COG0583	DNA-binding transcription factor activity
EYD00_25345	COG2204	response regulator
EYD00_25365	COG4221	oxidoreductase activity
EYD00_25385	COG1595	DNA-templated transcription, initiation
EYD00_25390	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYD00_25400	COG1028	Short-chain dehydrogenase reductase Sdr
EYD00_25410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EYD00_25420	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EYD00_25435	COG0583	DNA-binding transcription factor activity
EYD00_25450	COG4191	Histidine kinase
EYD00_25455	COG1959	2 iron, 2 sulfur cluster binding
EYD00_25485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EYD00_25500	COG2169	Transcriptional regulator
EYD00_25500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYD00_25520	COG4566	intracellular signal transduction
EYD00_25530	COG0601	transmembrane transport
EYD00_25535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYD00_25550	COG4566	intracellular signal transduction
EYD00_25555	COG4191	Histidine kinase
EYD00_25565	COG4566	intracellular signal transduction
EYD00_25600	COG4191	Histidine kinase
EYD00_25605	COG4566	intracellular signal transduction
EYD00_25620	COG0583	DNA-binding transcription factor activity
EYD00_25630	COG0583	DNA-binding transcription factor activity
EYD00_25635	COG0300	oxidoreductase activity
EYD00_25645	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EYD00_25655	COG2801	Transposase and inactivated derivatives
EYD00_25705	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYD00_25730	COG0071	Belongs to the small heat shock protein (HSP20) family
EYD00_25770	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EYD00_25775	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system