locus-tag	class	description
GSF67_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GSF67_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSF67_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GSF67_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GSF67_00025	COG1420	regulation of RNA biosynthetic process
GSF67_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GSF67_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSF67_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GSF67_00050	COG1137	ATPase activity
GSF67_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GSF67_00065	COG0616	signal peptide processing
GSF67_00070	COG0776	regulation of translation
GSF67_00080	COG0116	Belongs to the methyltransferase superfamily
GSF67_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GSF67_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSF67_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GSF67_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GSF67_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GSF67_00115	COG0728	peptidoglycan biosynthetic process
GSF67_00120	COG0346	lactoylglutathione lyase activity
GSF67_00125	COG0180	Tryptophanyl-tRNA synthetase
GSF67_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GSF67_00140	COG1214	PFAM Peptidase M22, glycoprotease
GSF67_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GSF67_00165	COG1702	phosphate starvation-inducible protein PhoH
GSF67_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GSF67_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GSF67_00185	COG1396	sequence-specific DNA binding
GSF67_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GSF67_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GSF67_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_00210	COG0242	peptide deformylase activity
GSF67_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GSF67_00220	COG0101	tRNA pseudouridine synthase activity
GSF67_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF67_00235	COG2171	N-acyltransferase activity
GSF67_00245	COG0840	transmembrane signaling receptor activity
GSF67_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF67_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GSF67_00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GSF67_00300	COG0706	membrane insertase activity
GSF67_00305	COG0594	ribonuclease P activity
GSF67_00310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GSF67_00320	COG0840	transmembrane signaling receptor activity
GSF67_00340	COG2226	methyltransferase
GSF67_00345	COG3842	ATPase activity
GSF67_00350	COG1175	transmembrane transport
GSF67_00355	COG0395	ABC-type sugar transport system, permease component
GSF67_00370	COG0427	acetyl-CoA hydrolase
GSF67_00380	COG3938	Belongs to the proline racemase family
GSF67_00385	COG0418	dihydroorotase activity
GSF67_00390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GSF67_00410	COG0166	Belongs to the GPI family
GSF67_00415	COG0318	PFAM AMP-dependent synthetase and ligase
GSF67_00420	COG3842	ATPase activity
GSF67_00425	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_00430	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GSF67_00435	COG4774	siderophore transport
GSF67_00475	COG2326	polyphosphate kinase activity
GSF67_00480	COG5002	protein histidine kinase activity
GSF67_00485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GSF67_00490	COG0573	inorganic phosphate transmembrane transporter activity
GSF67_00500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GSF67_00505	COG0704	Plays a role in the regulation of phosphate uptake
GSF67_00510	COG0745	RESPONSE REGULATOR receiver
GSF67_00525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GSF67_00530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GSF67_00540	COG2967	ApaG domain
GSF67_00550	COG0717	Belongs to the dCTP deaminase family
GSF67_00560	COG0582	viral genome integration into host DNA
GSF67_00575	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_00600	COG3501	Rhs element vgr protein
GSF67_00675	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GSF67_00695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GSF67_00750	COG0167	dihydroorotate dehydrogenase activity
GSF67_00765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_00785	COG1959	2 iron, 2 sulfur cluster binding
GSF67_00790	COG1201	RNA secondary structure unwinding
GSF67_00810	COG0730	response to heat
GSF67_00825	COG1960	acyl-CoA dehydrogenase activity
GSF67_00830	COG0183	Belongs to the thiolase family
GSF67_00835	COG1024	Enoyl-CoA hydratase
GSF67_00835	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSF67_00860	COG1320	monovalent cation:proton antiporter activity
GSF67_00865	COG2212	antiporter activity
GSF67_00870	COG1863	multisubunit Na H antiporter MnhE subunit
GSF67_00875	COG0651	ATP synthesis coupled electron transport
GSF67_00880	COG1006	Multisubunit Na H antiporter MnhC subunit
GSF67_00885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GSF67_00885	COG2111	Na H antiporter
GSF67_00895	COG0840	transmembrane signaling receptor activity
GSF67_00905	COG0745	RESPONSE REGULATOR receiver
GSF67_00910	COG2198	Histidine kinase
GSF67_00910	COG0643	Histidine kinase
GSF67_00915	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GSF67_00920	COG2201	protein-glutamate methylesterase activity
GSF67_00925	COG0745	RESPONSE REGULATOR receiver
GSF67_00930	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
GSF67_00940	COG1766	The M ring may be actively involved in energy transduction
GSF67_00945	COG2771	luxR family
GSF67_00955	COG0840	transmembrane signaling receptor activity
GSF67_00955	COG2972	Histidine kinase
GSF67_00960	COG0784	Response regulator, receiver
GSF67_00960	COG2205	protein histidine kinase activity
GSF67_00960	COG2198	Histidine kinase
GSF67_00965	COG1970	mechanosensitive ion channel activity
GSF67_00970	COG0436	Aminotransferase
GSF67_00985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GSF67_00990	COG0424	maF-like protein
GSF67_00995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GSF67_01005	COG5328	Belongs to the UPF0262 family
GSF67_01010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GSF67_01020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GSF67_01355	COG1338	Plays a role in the flagellum-specific transport system
GSF67_01365	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GSF67_01375	COG1706	bacterial-type flagellum-dependent cell motility
GSF67_01380	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
GSF67_01385	COG4786	Flagellar basal body rod
GSF67_01390	COG1677	Flagellar hook-basal body complex protein FliE
GSF67_01395	COG1558	bacterial-type flagellum-dependent cell motility
GSF67_01400	COG1815	bacterial-type flagellum-dependent cell motility
GSF67_01410	COG1157	protein secretion by the type III secretion system
GSF67_01415	COG4786	Flagellar basal body rod
GSF67_01425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GSF67_01430	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSF67_01435	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSF67_01440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GSF67_01445	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GSF67_01470	COG1360	Flagellar Motor Protein
GSF67_01495	COG1749	Flagellar hook protein flgE
GSF67_01515	COG5443	negative regulation of bacterial-type flagellum assembly
GSF67_01520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GSF67_01530	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GSF67_01570	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GSF67_01575	COG1609	Transcriptional regulator
GSF67_01580	COG1653	transport
GSF67_01585	COG1175	transmembrane transport
GSF67_01590	COG0395	ABC-type sugar transport system, permease component
GSF67_01595	COG0366	Alpha amylase catalytic
GSF67_01600	COG3842	ATPase activity
GSF67_01615	COG0129	dihydroxy-acid dehydratase activity
GSF67_01620	COG0363	glucosamine-6-phosphate deaminase activity
GSF67_01625	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GSF67_01630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_01640	COG2081	HI0933 family
GSF67_01660	COG2224	Isocitrate lyase
GSF67_01675	COG3842	ATPase activity
GSF67_01680	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF67_01685	COG1177	transmembrane transport
GSF67_01695	COG2205	protein histidine kinase activity
GSF67_01705	COG0248	Ppx GppA phosphatase
GSF67_01710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GSF67_01715	COG0477	Major facilitator Superfamily
GSF67_01765	COG0521	Mo-molybdopterin cofactor biosynthetic process
GSF67_01770	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GSF67_01780	COG0142	geranyltranstransferase activity
GSF67_01805	COG0752	glycyl-tRNA synthetase alpha subunit
GSF67_01815	COG1704	LemA family
GSF67_01820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GSF67_01830	COG0751	glycine-tRNA ligase activity
GSF67_01835	COG1683	Conserved Protein
GSF67_01840	COG0840	transmembrane signaling receptor activity
GSF67_01850	COG0151	Belongs to the GarS family
GSF67_01855	COG2183	response to ionizing radiation
GSF67_01860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF67_01870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GSF67_01885	COG0583	DNA-binding transcription factor activity
GSF67_01905	COG0306	phosphate transporter
GSF67_01915	COG0561	phosphatase activity
GSF67_01920	COG0438	transferase activity, transferring glycosyl groups
GSF67_01925	COG2186	Transcriptional regulator
GSF67_01940	COG0583	DNA-binding transcription factor activity
GSF67_01945	COG0277	FAD linked oxidase domain protein
GSF67_01955	COG0277	FAD linked oxidase domain protein
GSF67_01960	COG0247	lactate metabolic process
GSF67_01970	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_01975	COG2818	Glycosylase
GSF67_01985	COG2855	membrane
GSF67_01990	COG0583	DNA-binding transcription factor activity
GSF67_02010	COG0124	histidyl-tRNA synthetase
GSF67_02020	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GSF67_02025	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GSF67_02030	COG2259	Doxx family
GSF67_02045	COG0459	protein refolding
GSF67_02050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GSF67_02060	COG0196	riboflavin kinase activity
GSF67_02065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GSF67_02075	COG0590	tRNA wobble adenosine to inosine editing
GSF67_02080	COG1187	pseudouridine synthase activity
GSF67_02085	COG0742	ribosomal rna small subunit methyltransferase
GSF67_02090	COG1752	Esterase of the alpha-beta hydrolase superfamily
GSF67_02100	COG0312	modulator of DNA gyrase
GSF67_02105	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_02115	COG1519	Transferase
GSF67_02125	COG1663	tetraacyldisaccharide 4'-kinase activity
GSF67_02135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GSF67_02145	COG3300	MHYT domain
GSF67_02145	COG5001	Diguanylate cyclase
GSF67_02155	COG3386	PFAM SMP-30 Gluconolaconase
GSF67_02160	COG0800	Aldolase
GSF67_02165	COG3734	2-keto-3-deoxy-galactonokinase
GSF67_02170	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_02180	COG2197	response regulator
GSF67_02185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_02195	COG0598	Magnesium transport protein CorA
GSF67_02200	COG3158	transport of potassium into the cell
GSF67_02215	COG0356	it plays a direct role in the translocation of protons across the membrane
GSF67_02225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GSF67_02230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GSF67_02245	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GSF67_02265	COG0009	L-threonylcarbamoyladenylate synthase
GSF67_02275	COG4638	Rieske (2fe-2S)
GSF67_02300	COG1960	acyl-CoA dehydrogenase activity
GSF67_02320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GSF67_02325	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
GSF67_02330	COG0840	transmembrane signaling receptor activity
GSF67_02340	COG1522	sequence-specific DNA binding
GSF67_02370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GSF67_02375	COG1741	Belongs to the pirin family
GSF67_02380	COG1722	exodeoxyribonuclease VII activity
GSF67_02385	COG0123	including yeast histone deacetylase and acetoin utilization protein
GSF67_02390	COG1268	BioY protein
GSF67_02395	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GSF67_02400	COG1122	ATPase activity
GSF67_02405	COG3214	Protein conserved in bacteria
GSF67_02410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSF67_02410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSF67_02415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GSF67_02430	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GSF67_02445	COG0259	pyridoxamine-phosphate oxidase activity
GSF67_02460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_02470	COG0312	modulator of DNA gyrase
GSF67_02485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSF67_02490	COG0109	protoheme IX farnesyltransferase activity
GSF67_02500	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GSF67_02515	COG3346	SURF1 family
GSF67_02520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GSF67_02525	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GSF67_02530	COG0328	RNA-DNA hybrid ribonuclease activity
GSF67_02545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GSF67_02545	COG0678	peroxiredoxin activity
GSF67_02555	COG1678	Uncharacterized ACR, COG1678
GSF67_02575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSF67_02580	COG0612	Peptidase, M16
GSF67_02605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_02610	COG1802	Transcriptional regulator
GSF67_02625	COG2189	Belongs to the N(4) N(6)-methyltransferase family
GSF67_02635	COG3609	addiction module antidote protein, CC2985 family
GSF67_02650	COG1194	a g-specific adenine glycosylase
GSF67_02660	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GSF67_02665	COG1196	nuclear chromosome segregation
GSF67_02670	COG2514	catechol 2,3-dioxygenase activity
GSF67_02675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GSF67_02675	COG0574	Belongs to the PEP-utilizing enzyme family
GSF67_02715	COG0579	oxidoreductase
GSF67_02740	COG2895	sulfate adenylyltransferase (ATP) activity
GSF67_02745	COG0175	sulfate reduction
GSF67_02750	COG0175	sulfate reduction
GSF67_02755	COG1959	2 iron, 2 sulfur cluster binding
GSF67_02760	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GSF67_02765	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GSF67_02770	COG4208	sulfate ABC transporter
GSF67_02775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GSF67_02795	COG2199	diguanylate cyclase activity
GSF67_02795	COG2200	EAL domain
GSF67_02795	COG2203	Gaf domain
GSF67_02805	COG1309	transcriptional regulator
GSF67_02810	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_02815	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GSF67_02860	COG0477	Major facilitator Superfamily
GSF67_02870	COG1793	dna ligase
GSF67_02870	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GSF67_02890	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_02895	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_02900	COG1846	Transcriptional regulator
GSF67_02905	COG1764	response to oxidative stress
GSF67_02920	COG0488	(ABC) transporter
GSF67_02955	COG4221	oxidoreductase activity
GSF67_02970	COG0433	COG0433 Predicted ATPase
GSF67_02985	COG1733	regulation of RNA biosynthetic process
GSF67_02990	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
GSF67_03000	COG1280	lysine exporter protein (LysE YggA)
GSF67_03005	COG0656	L-ascorbic acid biosynthetic process
GSF67_03010	COG3781	membrane
GSF67_03015	COG2378	regulation of single-species biofilm formation
GSF67_03025	COG4106	trans-aconitate 2-methyltransferase activity
GSF67_03030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSF67_03035	COG0840	transmembrane signaling receptor activity
GSF67_03040	COG0583	DNA-binding transcription factor activity
GSF67_03055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GSF67_03065	COG2378	regulation of single-species biofilm formation
GSF67_03075	COG3909	cytochrome
GSF67_03080	COG2010	Cytochrome c
GSF67_03115	COG0789	Transcriptional regulator
GSF67_03140	COG4175	Glycine betaine
GSF67_03145	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_03170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_03180	COG2169	Transcriptional regulator
GSF67_03180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF67_03190	COG2514	catechol 2,3-dioxygenase activity
GSF67_03205	COG1272	protein, Hemolysin III
GSF67_03215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSF67_03225	COG2111	Na H antiporter
GSF67_03230	COG1006	Multisubunit Na H antiporter MnhC subunit
GSF67_03245	COG2212	antiporter activity
GSF67_03250	COG1320	monovalent cation:proton antiporter activity
GSF67_03255	COG4957	zinc ion binding
GSF67_03270	COG2166	iron-sulfur cluster assembly
GSF67_03280	COG2205	protein histidine kinase activity
GSF67_03335	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSF67_03340	COG2983	Belongs to the UPF0260 family
GSF67_03375	COG2337	Toxic component of a toxin-antitoxin (TA) module
GSF67_03385	COG2814	Major facilitator Superfamily
GSF67_03395	COG1621	beta-fructofuranosidase activity
GSF67_03400	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GSF67_03450	COG4695	Portal protein
GSF67_03540	COG0745	RESPONSE REGULATOR receiver
GSF67_03545	COG5002	protein histidine kinase activity
GSF67_03555	COG4235	cytochrome complex assembly
GSF67_03560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GSF67_03565	COG1138	Cytochrome C-type biogenesis protein
GSF67_03570	COG3088	subunit of a heme lyase
GSF67_03575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSF67_03585	COG2205	protein histidine kinase activity
GSF67_03590	COG3011	Protein conserved in bacteria
GSF67_03600	COG3713	MltA-interacting MipA family protein
GSF67_03605	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GSF67_03610	COG2202	Pas domain
GSF67_03610	COG2205	protein histidine kinase activity
GSF67_03620	COG0308	aminopeptidase N
GSF67_03625	COG0697	spore germination
GSF67_03645	COG0443	Heat shock 70 kDa protein
GSF67_03655	COG0300	oxidoreductase activity
GSF67_03685	COG0604	alcohol dehydrogenase
GSF67_03690	COG1733	regulation of RNA biosynthetic process
GSF67_03695	COG1968	undecaprenyl-diphosphatase activity
GSF67_03700	COG2239	Acts as a magnesium transporter
GSF67_03705	COG2814	Major facilitator Superfamily
GSF67_03735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GSF67_03760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GSF67_03810	COG0741	lytic transglycosylase activity
GSF67_03820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_03825	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GSF67_03835	COG0840	transmembrane signaling receptor activity
GSF67_03845	COG1758	RNA polymerase activity
GSF67_03865	COG0736	holo-[acyl-carrier-protein] synthase activity
GSF67_03870	COG0681	Belongs to the peptidase S26 family
GSF67_03875	COG0571	ribonuclease III activity
GSF67_03880	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GSF67_03885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSF67_03890	COG0784	Response regulator, receiver
GSF67_03895	COG1381	Involved in DNA repair and RecF pathway recombination
GSF67_03905	COG2226	methyltransferase
GSF67_03920	COG1418	mRNA catabolic process
GSF67_03930	COG0346	lactoylglutathione lyase activity
GSF67_03940	COG1116	anion transmembrane transporter activity
GSF67_03945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_03950	COG3443	Belongs to the bacterial solute-binding protein 9 family
GSF67_03955	COG0668	transmembrane transport
GSF67_03965	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GSF67_03990	COG1051	belongs to the nudix hydrolase family
GSF67_03995	COG1742	UPF0060 membrane protein
GSF67_04015	COG1183	phosphatidylcholine synthase activity
GSF67_04020	COG0688	phosphatidylethanolamine metabolic process
GSF67_04025	COG5265	(ABC) transporter
GSF67_04065	COG2852	Protein conserved in bacteria
GSF67_04075	COG0215	cysteine-tRNA ligase activity
GSF67_04080	COG4221	oxidoreductase activity
GSF67_04085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GSF67_04090	COG1286	toxin biosynthetic process
GSF67_04110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSF67_04120	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GSF67_04130	COG5265	(ABC) transporter
GSF67_04135	COG0305	Participates in initiation and elongation during chromosome replication
GSF67_04160	COG0359	binds to the 23S rRNA
GSF67_04170	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GSF67_04175	COG0360	Binds together with S18 to 16S ribosomal RNA
GSF67_04185	COG0667	Aldo Keto reductase
GSF67_04190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GSF67_04200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF67_04205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GSF67_04215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GSF67_04220	COG1561	YicC-like family, N-terminal region
GSF67_04225	COG0194	GDP metabolic process
GSF67_04230	COG0400	carboxylic ester hydrolase activity
GSF67_04235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GSF67_04240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GSF67_04250	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GSF67_04265	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GSF67_04285	COG3300	MHYT domain
GSF67_04285	COG5001	Diguanylate cyclase
GSF67_04290	COG4191	Histidine kinase
GSF67_04305	COG0488	(ABC) transporter
GSF67_04310	COG3706	GGDEF domain
GSF67_04320	COG0105	UTP biosynthetic process
GSF67_04340	COG0314	molybdopterin synthase activity
GSF67_04345	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GSF67_04350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GSF67_04355	COG0322	excinuclease ABC activity
GSF67_04360	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_04370	COG0625	glutathione transferase activity
GSF67_04385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GSF67_04390	COG0243	molybdopterin cofactor binding
GSF67_04405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GSF67_04410	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GSF67_04415	COG0628	permease
GSF67_04425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GSF67_04430	COG0248	Ppx GppA phosphatase
GSF67_04455	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GSF67_04465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GSF67_04470	COG0477	Major facilitator Superfamily
GSF67_04475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GSF67_04485	COG4452	Inner membrane protein CreD
GSF67_04490	COG0659	secondary active sulfate transmembrane transporter activity
GSF67_04500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSF67_04510	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GSF67_04520	COG0113	porphobilinogen synthase activity
GSF67_04540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GSF67_04545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GSF67_04550	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GSF67_04550	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GSF67_04560	COG1280	lysine exporter protein (LysE YggA)
GSF67_04565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GSF67_04570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSF67_04575	COG2814	Major facilitator Superfamily
GSF67_04580	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GSF67_04600	COG0416	fatty acid biosynthetic process
GSF67_04605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSF67_04610	COG0776	regulation of translation
GSF67_04645	COG0601	transmembrane transport
GSF67_04650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_04655	COG0444	Belongs to the ABC transporter superfamily
GSF67_04675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GSF67_04680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSF67_04695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GSF67_04700	COG0583	DNA-binding transcription factor activity
GSF67_04705	COG0737	Belongs to the 5'-nucleotidase family
GSF67_04730	COG2897	thiosulfate sulfurtransferase activity
GSF67_04745	COG0415	Belongs to the DNA photolyase family
GSF67_04755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF67_04785	COG3932	Exopolysaccharide synthesis, ExoD
GSF67_04865	COG1612	heme a metabolic process
GSF67_04875	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GSF67_04880	COG0010	Belongs to the arginase family
GSF67_04885	COG1396	sequence-specific DNA binding
GSF67_04890	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GSF67_04895	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GSF67_04900	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GSF67_04915	COG1832	CoA-binding protein
GSF67_04940	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_04945	COG2124	cytochrome p450
GSF67_04950	COG2199	diguanylate cyclase activity
GSF67_04955	COG0740	serine-type endopeptidase activity
GSF67_04960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GSF67_04970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GSF67_04980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GSF67_05015	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_05020	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_05025	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_05035	COG0649	NAD binding
GSF67_05045	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
GSF67_05050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GSF67_05060	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GSF67_05065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GSF67_05075	COG0713	ATP synthesis coupled electron transport
GSF67_05090	COG1007	ATP synthesis coupled electron transport
GSF67_05115	COG0442	prolyl-tRNA aminoacylation
GSF67_05125	COG1136	(ABC) transporter
GSF67_05145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSF67_05155	COG0784	Response regulator, receiver
GSF67_05170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GSF67_05175	COG0477	Major facilitator Superfamily
GSF67_05190	COG0557	exoribonuclease II activity
GSF67_05195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GSF67_05205	COG0758	DNA mediated transformation
GSF67_05210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GSF67_05220	COG0540	Belongs to the ATCase OTCase family
GSF67_05230	COG1960	acyl-CoA dehydrogenase activity
GSF67_05235	COG0456	acetyltransferase
GSF67_05265	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GSF67_05270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GSF67_05275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF67_05280	COG0154	amidase activity
GSF67_05285	COG0456	acetyltransferase
GSF67_05290	COG3811	Belongs to the UPF0386 family
GSF67_05305	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF67_05315	COG0456	acetyltransferase
GSF67_05330	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GSF67_05335	COG0439	Biotin carboxylase
GSF67_05340	COG0511	ligase activity, forming carbon-carbon bonds
GSF67_05345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GSF67_05355	COG0436	Aminotransferase
GSF67_05375	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_05380	COG1530	ribonuclease E activity
GSF67_05395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSF67_05415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GSF67_05420	COG0384	phenazine biosynthesis protein PhzF
GSF67_05440	COG0633	Ferredoxin
GSF67_05450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GSF67_05455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GSF67_05460	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GSF67_05470	COG3768	UPF0283 membrane protein
GSF67_05475	COG3106	COG3106 Predicted ATPase
GSF67_05505	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GSF67_05535	COG0537	adenosine 5'-monophosphoramidase activity
GSF67_05560	COG0052	Belongs to the universal ribosomal protein uS2 family
GSF67_05565	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GSF67_05570	COG0528	UMP kinase activity
GSF67_05575	COG0233	cytoplasmic translational termination
GSF67_05580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GSF67_05590	COG0750	zinc metalloprotease
GSF67_05595	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GSF67_05600	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GSF67_05605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF67_05610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GSF67_05615	COG3494	Protein of unknown function (DUF1009)
GSF67_05620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GSF67_05625	COG2186	Transcriptional regulator
GSF67_05635	COG0765	amino acid transport
GSF67_05650	COG0372	Belongs to the citrate synthase family
GSF67_05665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GSF67_05670	COG4598	ABC transporter
GSF67_05675	COG0765	amino acid transport
GSF67_05685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_05690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_05695	COG3842	ATPase activity
GSF67_05700	COG0395	ABC-type sugar transport system, permease component
GSF67_05710	COG2182	Extracellular solute-binding protein
GSF67_05720	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_05725	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_05730	COG1063	alcohol dehydrogenase
GSF67_05735	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GSF67_05755	COG0683	leucine binding
GSF67_05760	COG1960	acyl-CoA dehydrogenase activity
GSF67_05775	COG1024	Enoyl-CoA hydratase
GSF67_05790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_05810	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GSF67_05815	COG0148	phosphopyruvate hydratase activity
GSF67_05830	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSF67_05835	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSF67_05835	COG0022	dehydrogenase e1 component
GSF67_05845	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSF67_05855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GSF67_05865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GSF67_05870	COG0697	spore germination
GSF67_05890	COG2867	negative regulation of translational initiation
GSF67_05895	COG1546	Belongs to the CinA family
GSF67_05900	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GSF67_05900	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GSF67_05910	COG3852	Histidine kinase
GSF67_05915	COG2204	response regulator
GSF67_05920	COG5000	phosphorelay sensor kinase activity
GSF67_05925	COG2204	response regulator
GSF67_05930	COG0569	domain protein
GSF67_05935	COG1923	regulation of RNA biosynthetic process
GSF67_05940	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GSF67_05945	COG3956	TIGRFAM MazG family protein
GSF67_05955	COG1648	precorrin-2 dehydrogenase activity
GSF67_05955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSF67_05970	COG0275	rRNA processing
GSF67_05995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSF67_05995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GSF67_06000	COG0509	glycine decarboxylation via glycine cleavage system
GSF67_06005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_06030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GSF67_06040	COG0546	phosphoglycolate phosphatase activity
GSF67_06055	COG0251	oxidation-reduction process
GSF67_06060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GSF67_06070	COG1671	Belongs to the UPF0178 family
GSF67_06080	COG0450	alkyl hydroperoxide reductase
GSF67_06120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSF67_06125	COG2801	Transposase and inactivated derivatives
GSF67_06130	COG0431	NADPH-dependent FMN reductase
GSF67_06160	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GSF67_06160	COG0321	lipoyl(octanoyl) transferase activity
GSF67_06165	COG0084	hydrolase, TatD family'
GSF67_06170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF67_06180	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GSF67_06235	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GSF67_06240	COG2095	MarC family integral membrane protein
GSF67_06245	COG0517	IMP dehydrogenase activity
GSF67_06245	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GSF67_06245	COG0617	tRNA 3'-terminal CCA addition
GSF67_06255	COG3609	addiction module antidote protein, CC2985 family
GSF67_06260	COG0629	single-stranded DNA binding
GSF67_06265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GSF67_06275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GSF67_06280	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSF67_06295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF67_06300	COG1121	(ABC) transporter
GSF67_06320	COG0667	Aldo Keto reductase
GSF67_06330	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GSF67_06400	COG0668	transmembrane transport
GSF67_06430	COG2239	Acts as a magnesium transporter
GSF67_06435	COG0243	molybdopterin cofactor binding
GSF67_06445	COG0242	peptide deformylase activity
GSF67_06475	COG0321	lipoyl(octanoyl) transferase activity
GSF67_06480	COG1064	alcohol dehydrogenase
GSF67_06510	COG1862	Preprotein translocase
GSF67_06540	COG2124	cytochrome p450
GSF67_06555	COG0596	Alpha beta hydrolase
GSF67_06565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSF67_06570	COG0626	cystathionine gamma-synthase activity
GSF67_06575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_06580	COG4597	amino acid ABC transporter
GSF67_06585	COG0765	amino acid transport
GSF67_06590	COG1126	abc transporter atp-binding protein
GSF67_06615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GSF67_06630	COG0436	Aminotransferase
GSF67_06660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GSF67_06670	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF67_06675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF67_06680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GSF67_06695	COG3243	poly(R)-hydroxyalkanoic acid synthase
GSF67_06700	COG1489	DNA binding
GSF67_06705	COG0024	Methionine aminopeptidase
GSF67_06755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_06870	COG2963	transposase activity
GSF67_06880	COG4372	Transposase
GSF67_06930	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GSF67_06950	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GSF67_06955	COG0546	phosphoglycolate phosphatase activity
GSF67_06970	COG0114	fumarate hydratase activity
GSF67_06980	COG0504	CTP synthase activity
GSF67_06990	COG0149	triose-phosphate isomerase activity
GSF67_07000	COG0187	DNA topoisomerase II activity
GSF67_07065	COG0326	Molecular chaperone. Has ATPase activity
GSF67_07080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GSF67_07105	COG1309	transcriptional regulator
GSF67_07120	COG0740	serine-type endopeptidase activity
GSF67_07130	COG0640	Transcriptional regulator
GSF67_07135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSF67_07140	COG0745	RESPONSE REGULATOR receiver
GSF67_07150	COG3264	Mechanosensitive ion channel
GSF67_07150	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GSF67_07225	COG1127	ABC transporter
GSF67_07230	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GSF67_07235	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_07255	COG0281	malic enzyme
GSF67_07255	COG0280	phosphate acetyltransferase
GSF67_07265	COG0778	Nitroreductase
GSF67_07270	COG0823	Involved in the tonB-independent uptake of proteins
GSF67_07280	COG1368	sulfuric ester hydrolase activity
GSF67_07305	COG4977	sequence-specific DNA binding
GSF67_07320	COG0544	peptidyl-prolyl cis-trans isomerase activity
GSF67_07345	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GSF67_07350	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GSF67_07380	COG0512	Glutamine amidotransferase of anthranilate synthase
GSF67_07380	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GSF67_07385	COG0343	queuine tRNA-ribosyltransferase activity
GSF67_07390	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GSF67_07405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GSF67_07430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GSF67_07435	COG0134	indole-3-glycerol-phosphate synthase activity
GSF67_07440	COG0315	cyclic pyranopterin monophosphate synthase activity
GSF67_07445	COG0303	'Molybdopterin
GSF67_07450	COG3706	GGDEF domain
GSF67_07465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GSF67_07465	COG0475	glutathione-regulated potassium exporter activity
GSF67_07475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GSF67_07480	COG0697	spore germination
GSF67_07485	COG2814	Major facilitator Superfamily
GSF67_07490	COG0746	molybdenum cofactor guanylyltransferase activity
GSF67_07495	COG1763	Mo-molybdopterin cofactor biosynthetic process
GSF67_07500	COG0739	heme binding
GSF67_07505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GSF67_07510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GSF67_07515	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GSF67_07520	COG0805	protein transport
GSF67_07525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GSF67_07530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GSF67_07535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GSF67_07540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GSF67_07545	COG1472	Belongs to the glycosyl hydrolase 3 family
GSF67_07555	COG0018	arginyl-trna synthetase
GSF67_07560	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GSF67_07565	COG0316	Belongs to the HesB IscA family
GSF67_07580	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GSF67_07595	COG0525	valine-tRNA ligase activity
GSF67_07605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GSF67_07650	COG0655	NAD(P)H dehydrogenase (quinone) activity
GSF67_07655	COG1546	Belongs to the CinA family
GSF67_07655	COG1058	Belongs to the CinA family
GSF67_07660	COG0589	response to stress
GSF67_07665	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GSF67_07670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GSF67_07685	COG1914	H( )-stimulated, divalent metal cation uptake system
GSF67_07695	COG1132	(ABC) transporter
GSF67_07700	COG0628	permease
GSF67_07720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_07735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GSF67_07745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GSF67_07755	COG0302	gtp cyclohydrolase
GSF67_07760	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GSF67_07765	COG1752	Esterase of the alpha-beta hydrolase superfamily
GSF67_07770	COG0516	GMP reductase activity
GSF67_07770	COG0517	IMP dehydrogenase activity
GSF67_07805	COG1760	l-serine dehydratase
GSF67_07840	COG0583	DNA-binding transcription factor activity
GSF67_07855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GSF67_07855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GSF67_07860	COG0347	Belongs to the P(II) protein family
GSF67_07865	COG0174	glutamine synthetase
GSF67_07895	COG0697	spore germination
GSF67_07910	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GSF67_07920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GSF67_07950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GSF67_07955	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GSF67_07960	COG2186	Transcriptional regulator
GSF67_07980	COG1129	ABC transporter
GSF67_07985	COG1183	phosphatidylcholine synthase activity
GSF67_07990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSF67_07995	COG0679	Auxin Efflux Carrier
GSF67_08000	COG0785	Cytochrome C biogenesis protein
GSF67_08040	COG1278	Cold shock
GSF67_08170	COG0433	COG0433 Predicted ATPase
GSF67_08200	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GSF67_08225	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GSF67_08260	COG1475	DNA binding
GSF67_08285	COG3750	Belongs to the UPF0335 family
GSF67_08500	COG0582	viral genome integration into host DNA
GSF67_08520	COG2267	carboxylic ester hydrolase activity
GSF67_08535	COG1136	(ABC) transporter
GSF67_08535	COG0577	efflux transmembrane transporter activity
GSF67_08540	COG0577	efflux transmembrane transporter activity
GSF67_08540	COG1136	(ABC) transporter
GSF67_08555	COG2151	metal-sulfur cluster biosynthetic enzyme
GSF67_08560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GSF67_08565	COG0719	Fe-S assembly protein
GSF67_08570	COG0396	ATPase activity
GSF67_08580	COG0719	Fe-S assembly protein
GSF67_08585	COG1104	cysteine desulfurase activity
GSF67_08590	COG2945	thiolester hydrolase activity
GSF67_08595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GSF67_08600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GSF67_08610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GSF67_08615	COG2833	Protein of unknown function (DUF455)
GSF67_08620	COG0739	heme binding
GSF67_08625	COG0513	Belongs to the DEAD box helicase family
GSF67_08665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GSF67_08675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GSF67_08680	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSF67_08685	COG0047	phosphoribosylformylglycinamidine synthase activity
GSF67_08700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_08710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GSF67_08730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GSF67_08735	COG2814	Major facilitator Superfamily
GSF67_08740	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_08745	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_08750	COG0037	tRNA processing
GSF67_08755	COG2066	Belongs to the glutaminase family
GSF67_08760	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GSF67_08765	COG0861	Integral membrane protein TerC family
GSF67_08780	COG1280	lysine exporter protein (LysE YggA)
GSF67_08795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GSF67_08800	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
GSF67_08810	COG0538	isocitrate dehydrogenase activity
GSF67_08825	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GSF67_08830	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GSF67_08835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_08840	COG2313	pseudouridylate synthase activity
GSF67_08855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_08860	COG4215	(ABC) transporter
GSF67_08870	COG5425	PFAM Usg family protein
GSF67_08880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_08885	COG1522	sequence-specific DNA binding
GSF67_08890	COG1573	uracil-dna glycosylase
GSF67_08900	COG2202	Pas domain
GSF67_08900	COG2205	protein histidine kinase activity
GSF67_08910	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GSF67_08915	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GSF67_08930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GSF67_08940	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_08945	COG1129	ABC transporter
GSF67_08955	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_08960	COG3959	Transketolase, thiamine diphosphate binding domain
GSF67_08965	COG3958	Transketolase
GSF67_08970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GSF67_08975	COG2390	Transcriptional regulator
GSF67_08985	COG0842	Transport permease protein
GSF67_08990	COG1131	(ABC) transporter
GSF67_09025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GSF67_09030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GSF67_09045	COG0129	dihydroxy-acid dehydratase activity
GSF67_09050	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GSF67_09055	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
GSF67_09065	COG3739	integral membrane protein
GSF67_09070	COG0203	ribosomal protein L17
GSF67_09075	COG0202	RNA polymerase activity
GSF67_09080	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GSF67_09085	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GSF67_09090	COG0563	adenylate kinase activity
GSF67_09095	COG0201	protein transport
GSF67_09100	COG0200	Binds to the 23S rRNA
GSF67_09105	COG1841	ribosomal large subunit assembly
GSF67_09110	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GSF67_09115	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GSF67_09120	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GSF67_09125	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GSF67_09130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GSF67_09135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GSF67_09140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GSF67_09145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GSF67_09150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GSF67_09155	COG0255	Belongs to the universal ribosomal protein uL29 family
GSF67_09160	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GSF67_09165	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GSF67_09170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GSF67_09175	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GSF67_09180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GSF67_09185	COG0089	rRNA binding
GSF67_09190	COG0088	Forms part of the polypeptide exit tunnel
GSF67_09195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GSF67_09200	COG0051	transcription antitermination factor activity, RNA binding
GSF67_09205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GSF67_09210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GSF67_09215	COG0049	tRNA binding
GSF67_09220	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GSF67_09240	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GSF67_09245	COG0085	RNA polymerase activity
GSF67_09250	COG0222	ribosome binding
GSF67_09255	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GSF67_09260	COG0081	regulation of translation
GSF67_09265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GSF67_09275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GSF67_09285	COG1086	Polysaccharide biosynthesis protein
GSF67_09290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GSF67_09295	COG0861	Integral membrane protein TerC family
GSF67_09310	COG3895	Periplasmic Protein
GSF67_09335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF67_09355	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GSF67_09390	COG2198	Histidine kinase
GSF67_09390	COG0784	Response regulator, receiver
GSF67_09390	COG2205	protein histidine kinase activity
GSF67_09390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_09395	COG0784	Response regulator, receiver
GSF67_09400	COG3920	Histidine kinase
GSF67_09400	COG2202	Pas domain
GSF67_09405	COG0784	Response regulator, receiver
GSF67_09410	COG4251	negative regulation of phosphorylation
GSF67_09430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GSF67_09460	COG2910	NAD(P)H-binding
GSF67_09465	COG1733	regulation of RNA biosynthetic process
GSF67_09470	COG0556	nucleotide-excision repair
GSF67_09475	COG2382	esterase
GSF67_09495	COG0484	heat shock protein binding
GSF67_09545	COG3706	GGDEF domain
GSF67_09555	COG3842	ATPase activity
GSF67_09565	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_09570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_09585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GSF67_09595	COG2207	Transcriptional regulator
GSF67_09600	COG1064	alcohol dehydrogenase
GSF67_09605	COG1252	NADH dehydrogenase
GSF67_09610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GSF67_09615	COG2197	response regulator
GSF67_09620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GSF67_09650	COG0656	L-ascorbic acid biosynthetic process
GSF67_09665	COG0440	acetolactate synthase activity
GSF67_09670	COG0028	Belongs to the TPP enzyme family
GSF67_09680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GSF67_09685	COG0560	Phosphoserine phosphatase
GSF67_09685	COG3830	Belongs to the UPF0237 family
GSF67_09695	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_09710	COG0330	HflC and HflK could
GSF67_09715	COG0330	HflC and HflK could
GSF67_09725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GSF67_09765	COG0277	FAD linked oxidase domain protein
GSF67_09770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_09825	COG1335	isochorismatase
GSF67_09845	COG0006	proline dipeptidase activity
GSF67_09855	COG2264	protein methyltransferase activity
GSF67_09860	COG1999	signal sequence binding
GSF67_09870	COG0835	chemotaxis
GSF67_09880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GSF67_09885	COG0583	DNA-binding transcription factor activity
GSF67_09895	COG1247	-acetyltransferase
GSF67_09905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GSF67_09910	COG0497	DNA recombination
GSF67_09915	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GSF67_09925	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GSF67_09930	COG0849	cell division
GSF67_09935	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GSF67_09940	COG1181	Belongs to the D-alanine--D-alanine ligase family
GSF67_09945	COG0477	Major facilitator Superfamily
GSF67_09950	COG5001	Diguanylate cyclase
GSF67_09950	COG3300	MHYT domain
GSF67_09955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GSF67_09960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GSF67_09965	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GSF67_09975	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GSF67_09980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSF67_09990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GSF67_10005	COG0275	rRNA processing
GSF67_10010	COG2001	Belongs to the MraZ family
GSF67_10015	COG3766	membrane
GSF67_10025	COG0754	glutathionylspermidine amidase activity
GSF67_10050	COG3023	N-Acetylmuramoyl-L-alanine amidase
GSF67_10080	COG4106	trans-aconitate 2-methyltransferase activity
GSF67_10100	COG2226	methyltransferase
GSF67_10110	COG2267	carboxylic ester hydrolase activity
GSF67_10115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GSF67_10130	COG0251	oxidation-reduction process
GSF67_10145	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_10150	COG2814	Major facilitator Superfamily
GSF67_10175	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_10190	COG0174	glutamine synthetase
GSF67_10195	COG0531	amino acid
GSF67_10205	COG1737	Transcriptional regulator
GSF67_10230	COG3842	ATPase activity
GSF67_10290	COG2968	Membrane
GSF67_10300	COG0432	Pfam Uncharacterised protein family UPF0047
GSF67_10315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GSF67_10320	COG0358	DNA primase activity
GSF67_10340	COG0505	Belongs to the CarA family
GSF67_10345	COG0534	Mate efflux family protein
GSF67_10360	COG2321	neutral zinc metallopeptidase
GSF67_10375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GSF67_10385	COG3706	GGDEF domain
GSF67_10400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GSF67_10410	COG1522	sequence-specific DNA binding
GSF67_10415	COG0492	ferredoxin-NADP+ reductase activity
GSF67_10420	COG0583	DNA-binding transcription factor activity
GSF67_10430	COG1902	pentaerythritol trinitrate reductase activity
GSF67_10465	COG0387	Pfam Sodium calcium exchanger
GSF67_10470	COG0436	Aminotransferase
GSF67_10475	COG2199	diguanylate cyclase activity
GSF67_10475	COG2200	EAL domain
GSF67_10495	COG1278	Cold shock
GSF67_10500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_10515	COG1846	Transcriptional regulator
GSF67_10520	COG0745	RESPONSE REGULATOR receiver
GSF67_10525	COG2205	protein histidine kinase activity
GSF67_10530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF67_10555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GSF67_10580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GSF67_10590	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GSF67_10605	COG0840	transmembrane signaling receptor activity
GSF67_10610	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_10620	COG3300	MHYT domain
GSF67_10620	COG5001	Diguanylate cyclase
GSF67_10625	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GSF67_10630	COG5001	Diguanylate cyclase
GSF67_10640	COG0193	aminoacyl-tRNA hydrolase activity
GSF67_10650	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GSF67_10670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GSF67_10675	COG2857	Cytochrome c1
GSF67_10675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GSF67_10690	COG3021	interspecies interaction between organisms
GSF67_10695	COG1132	(ABC) transporter
GSF67_10700	COG1132	(ABC) transporter
GSF67_10705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GSF67_10710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GSF67_10725	COG0408	coproporphyrinogen oxidase activity
GSF67_10740	COG0617	tRNA 3'-terminal CCA addition
GSF67_10755	COG0714	Associated with various cellular activities
GSF67_10775	COG0454	-acetyltransferase
GSF67_10780	COG0477	Major facilitator Superfamily
GSF67_10790	COG0435	Glutathione S-transferase
GSF67_10795	COG0494	nUDIX hydrolase
GSF67_10810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GSF67_10815	COG3135	benzoate transporter
GSF67_10830	COG1595	DNA-templated transcription, initiation
GSF67_10840	COG0740	serine-type endopeptidase activity
GSF67_10855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GSF67_10860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GSF67_10885	COG4175	Glycine betaine
GSF67_10900	COG1435	thymidine kinase activity
GSF67_10920	COG2862	Uncharacterized protein family, UPF0114
GSF67_10935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GSF67_10935	COG0512	Glutamine amidotransferase of anthranilate synthase
GSF67_10950	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GSF67_10965	COG0366	Alpha amylase catalytic
GSF67_10970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_10990	COG1160	GTP binding
GSF67_11010	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GSF67_11020	COG0024	Methionine aminopeptidase
GSF67_11030	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_11045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_11055	COG0583	DNA-binding transcription factor activity
GSF67_11070	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_11085	COG1304	FMN binding
GSF67_11095	COG1309	transcriptional regulator
GSF67_11100	COG1686	Belongs to the peptidase S11 family
GSF67_11110	COG2351	hydroxyisourate hydrolase activity
GSF67_11115	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GSF67_11130	COG3648	Uricase
GSF67_11130	COG3195	allantoin biosynthetic process
GSF67_11140	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GSF67_11150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_11150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GSF67_11160	COG0513	Belongs to the DEAD box helicase family
GSF67_11165	COG0697	spore germination
GSF67_11170	COG2259	Doxx family
GSF67_11175	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_11185	COG2308	Evidence 4 Homologs of previously reported genes of
GSF67_11195	COG1305	Transglutaminase-like
GSF67_11200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_11210	COG0456	acetyltransferase
GSF67_11225	COG4214	carbohydrate transport
GSF67_11230	COG1129	ABC transporter
GSF67_11235	COG4213	ABC transporter substrate-binding protein
GSF67_11365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF67_11375	COG0840	transmembrane signaling receptor activity
GSF67_11380	COG2814	Major facilitator Superfamily
GSF67_11385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GSF67_11385	COG0646	methionine synthase
GSF67_11395	COG4215	(ABC) transporter
GSF67_11400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_11435	COG1215	transferase activity, transferring glycosyl groups
GSF67_11470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSF67_11475	COG2346	COG2346, Truncated hemoglobins
GSF67_11500	COG1309	transcriptional regulator
GSF67_11515	COG0494	nUDIX hydrolase
GSF67_11530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_11535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_11560	COG1234	tRNA 3'-trailer cleavage
GSF67_11565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GSF67_11570	COG0830	nickel cation binding
GSF67_11575	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
GSF67_11590	COG0804	urea catabolic process
GSF67_11595	COG1442	glycosyl transferase family 8
GSF67_11600	COG3755	Protein conserved in bacteria
GSF67_11610	COG0832	Belongs to the urease beta subunit family
GSF67_11615	COG3813	Protein conserved in bacteria
GSF67_11620	COG0831	urea catabolic process
GSF67_11625	COG0829	nickel cation binding
GSF67_11640	COG0411	ABC transporter
GSF67_11650	COG0559	Belongs to the binding-protein-dependent transport system permease family
GSF67_11665	COG0174	glutamine synthetase
GSF67_11670	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_11675	COG5002	protein histidine kinase activity
GSF67_11675	COG0784	Response regulator, receiver
GSF67_11675	COG2198	Histidine kinase
GSF67_11725	COG1218	3'(2'),5'-bisphosphate nucleotidase
GSF67_11805	COG0564	pseudouridine synthase activity
GSF67_11815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GSF67_11830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GSF67_11860	COG0346	lactoylglutathione lyase activity
GSF67_11870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GSF67_11880	COG2832	Protein of unknown function (DUF454)
GSF67_11885	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GSF67_11890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_11895	COG4558	Periplasmic binding protein
GSF67_11905	COG3721	Heme iron utilization protein
GSF67_11920	COG2205	protein histidine kinase activity
GSF67_11960	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_11965	COG4605	iron ion homeostasis
GSF67_11970	COG4604	ABC transporter, ATP-binding protein
GSF67_11975	COG0783	Belongs to the Dps family
GSF67_11990	COG0583	DNA-binding transcription factor activity
GSF67_12000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_12020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GSF67_12025	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GSF67_12030	COG0288	reversible hydration of carbon dioxide
GSF67_12040	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GSF67_12060	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GSF67_12065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_12070	COG0778	Nitroreductase
GSF67_12075	COG2267	carboxylic ester hydrolase activity
GSF67_12080	COG0251	oxidation-reduction process
GSF67_12085	COG1335	isochorismatase
GSF67_12090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_12100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_12115	COG1175	transmembrane transport
GSF67_12120	COG0395	ABC-type sugar transport system, permease component
GSF67_12125	COG3842	ATPase activity
GSF67_12130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_12140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSF67_12155	COG4608	Belongs to the ABC transporter superfamily
GSF67_12160	COG0444	Belongs to the ABC transporter superfamily
GSF67_12170	COG0601	transmembrane transport
GSF67_12190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GSF67_12190	COG0392	lysyltransferase activity
GSF67_12230	COG2159	amidohydrolase
GSF67_12235	COG1960	acyl-CoA dehydrogenase activity
GSF67_12260	COG2205	protein histidine kinase activity
GSF67_12265	COG0745	RESPONSE REGULATOR receiver
GSF67_12275	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_12275	COG1902	pentaerythritol trinitrate reductase activity
GSF67_12290	COG3842	ATPase activity
GSF67_12295	COG3842	ATPase activity
GSF67_12305	COG0395	ABC-type sugar transport system, permease component
GSF67_12310	COG1175	transmembrane transport
GSF67_12320	COG1609	Transcriptional regulator
GSF67_12325	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GSF67_12375	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GSF67_12385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_12390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_12400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GSF67_12410	COG1509	lysine 2,3-aminomutase activity
GSF67_12425	COG0583	DNA-binding transcription factor activity
GSF67_12430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_12440	COG0725	ABC transporter, periplasmic molybdate-binding protein
GSF67_12445	COG4149	molybdate abc transporter
GSF67_12450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GSF67_12460	COG3191	aminopeptidase activity
GSF67_12465	COG2022	thiamine diphosphate biosynthetic process
GSF67_12480	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GSF67_12485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GSF67_12495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GSF67_12520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GSF67_12545	COG0438	transferase activity, transferring glycosyl groups
GSF67_12565	COG4166	transmembrane transport
GSF67_12570	COG0601	transmembrane transport
GSF67_12575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_12585	COG0438	transferase activity, transferring glycosyl groups
GSF67_12590	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GSF67_12595	COG3142	Participates in the control of copper homeostasis
GSF67_12600	COG2814	Major facilitator Superfamily
GSF67_12615	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_12620	COG1737	Transcriptional regulator
GSF67_12630	COG3842	ATPase activity
GSF67_12640	COG0395	ABC-type sugar transport system, permease component
GSF67_12645	COG1175	transmembrane transport
GSF67_12660	COG2188	Transcriptional regulator
GSF67_12665	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GSF67_12670	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GSF67_12675	COG1940	carbohydrate kinase activity
GSF67_12685	COG0671	phosphoesterase, PA-phosphatase related
GSF67_12690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GSF67_12695	COG0156	8-amino-7-oxononanoate synthase activity
GSF67_12705	COG0729	surface antigen
GSF67_12715	COG0835	chemotaxis
GSF67_12725	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GSF67_12735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GSF67_12740	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GSF67_12745	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GSF67_12750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GSF67_12755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GSF67_12770	COG4974	Belongs to the 'phage' integrase family
GSF67_12795	COG1280	lysine exporter protein (LysE YggA)
GSF67_12805	COG0508	dehydrogenase complex catalyzes the overall conversion of
GSF67_12815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GSF67_12820	COG0045	succinate-CoA ligase (ADP-forming) activity
GSF67_12825	COG0039	L-malate dehydrogenase activity
GSF67_12830	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GSF67_12865	COG2264	protein methyltransferase activity
GSF67_12880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GSF67_12885	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GSF67_12890	COG0181	hydroxymethylbilane synthase activity
GSF67_12925	COG1872	DUF167
GSF67_12930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GSF67_12945	COG0339	signal peptide processing
GSF67_12950	COG1846	Transcriptional regulator
GSF67_12955	COG2814	Major facilitator Superfamily
GSF67_12960	COG0137	argininosuccinate synthase activity
GSF67_12970	COG1280	lysine exporter protein (LysE YggA)
GSF67_12975	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GSF67_12980	COG4120	Belongs to the binding-protein-dependent transport system permease family
GSF67_12990	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GSF67_13005	COG2154	pterin-4-alpha-carbinolamine dehydratase
GSF67_13010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GSF67_13015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GSF67_13025	COG4181	ATPase activity
GSF67_13035	COG0670	Belongs to the BI1 family
GSF67_13050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GSF67_13055	COG4133	protoheme IX ABC transporter activity
GSF67_13060	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GSF67_13065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GSF67_13080	COG3706	GGDEF domain
GSF67_13090	COG2917	probably involved in intracellular septation
GSF67_13095	COG0552	protein localization to endoplasmic reticulum
GSF67_13100	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GSF67_13105	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GSF67_13115	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GSF67_13120	COG1605	Chorismate mutase
GSF67_13120	COG0287	Prephenate dehydrogenase
GSF67_13125	COG0228	four-way junction DNA binding
GSF67_13130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GSF67_13135	COG0336	Belongs to the RNA methyltransferase TrmD family
GSF67_13145	COG0335	large ribosomal subunit rRNA binding
GSF67_13155	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
GSF67_13160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_13180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GSF67_13195	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GSF67_13225	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GSF67_13235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GSF67_13240	COG0142	geranyltranstransferase activity
GSF67_13245	COG2885	chlorophyll binding
GSF67_13250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GSF67_13255	COG2223	nitrite transmembrane transporter activity
GSF67_13260	COG1349	DNA-binding transcription factor activity
GSF67_13265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GSF67_13270	COG2197	response regulator
GSF67_13275	COG1132	(ABC) transporter
GSF67_13285	COG3459	Glycosyltransferase 36 associated
GSF67_13290	COG1473	amidohydrolase
GSF67_13300	COG0579	oxidoreductase
GSF67_13310	COG0129	dihydroxy-acid dehydratase activity
GSF67_13315	COG2084	Dehydrogenase
GSF67_13320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_13325	COG0277	FAD linked oxidase domain protein
GSF67_13330	COG2186	Transcriptional regulator
GSF67_13340	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GSF67_13345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_13350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_13355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSF67_13365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GSF67_13370	COG0495	leucyl-tRNA aminoacylation
GSF67_13385	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GSF67_13400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GSF67_13405	COG1946	Acyl-CoA thioesterase
GSF67_13410	COG0347	Belongs to the P(II) protein family
GSF67_13415	COG0004	ammonium transporteR
GSF67_13420	COG1674	ftsk spoiiie
GSF67_13425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GSF67_13440	COG0745	RESPONSE REGULATOR receiver
GSF67_13450	COG1329	Transcriptional regulator
GSF67_13455	COG2902	Dehydrogenase
GSF67_13460	COG2270	Major facilitator Superfamily
GSF67_13475	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_13490	COG0494	nUDIX hydrolase
GSF67_13500	COG0793	Belongs to the peptidase S41A family
GSF67_13510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GSF67_13515	COG0799	negative regulation of ribosome biogenesis
GSF67_13520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GSF67_13525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GSF67_13530	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GSF67_13535	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GSF67_13550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GSF67_13555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GSF67_13580	COG0066	3-isopropylmalate dehydratase activity
GSF67_13585	COG0473	3-isopropylmalate dehydrogenase activity
GSF67_13590	COG1858	cytochrome C peroxidase
GSF67_13595	COG1797	cobyrinic acid a,c-diamide synthase activity
GSF67_13600	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSF67_13600	COG1648	precorrin-2 dehydrogenase activity
GSF67_13605	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
GSF67_13670	COG1492	cobalamin metabolic process
GSF67_13685	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_13690	COG3254	rhamnose metabolic process
GSF67_13695	COG0246	Mannitol dehydrogenase
GSF67_13700	COG1063	alcohol dehydrogenase
GSF67_13720	COG4214	carbohydrate transport
GSF67_13725	COG1129	ABC transporter
GSF67_13730	COG2186	Transcriptional regulator
GSF67_13735	COG2721	sulfolactate sulfo-lyase activity
GSF67_13740	COG0138	bifunctional purine biosynthesis protein purh
GSF67_13750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GSF67_13750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GSF67_13755	COG0501	Belongs to the peptidase M48B family
GSF67_13775	COG0357	Ribosomal RNA small subunit methyltransferase G
GSF67_13780	COG0445	tRNA wobble uridine modification
GSF67_13785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GSF67_13790	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GSF67_13800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GSF67_13805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GSF67_13810	COG0424	maF-like protein
GSF67_13815	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF67_13820	COG0237	dephospho-CoA kinase activity
GSF67_13830	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GSF67_13835	COG3030	protein affecting phage T7 exclusion by the F plasmid
GSF67_13845	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GSF67_13870	COG0179	Fumarylacetoacetate (FAA) hydrolase
GSF67_13885	COG0135	phosphoribosylanthranilate isomerase activity
GSF67_13890	COG0133	tryptophan synthase activity
GSF67_13895	COG0159	tryptophan synthase activity
GSF67_13900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GSF67_13915	COG1074	ATP-dependent DNA helicase activity
GSF67_13925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GSF67_13935	COG2205	protein histidine kinase activity
GSF67_13945	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GSF67_13950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSF67_13955	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
GSF67_13955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GSF67_13960	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GSF67_13965	COG0642	Histidine kinase
GSF67_13970	COG0745	RESPONSE REGULATOR receiver
GSF67_13975	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GSF67_13985	COG1072	(Pantothenic acid kinase))
GSF67_13990	COG0140	phosphoribosyl-ATP diphosphatase activity
GSF67_13995	COG0107	imidazoleglycerol-phosphate synthase activity
GSF67_14000	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GSF67_14005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GSF67_14015	COG0131	Imidazoleglycerol-phosphate dehydratase
GSF67_14020	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GSF67_14025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GSF67_14035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GSF67_14050	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
GSF67_14060	COG1643	Atp-dependent helicase
GSF67_14105	COG0514	ATP-dependent DNA helicase (RecQ)
GSF67_14130	COG1072	(Pantothenic acid kinase))
GSF67_14140	COG1780	Probably involved in ribonucleotide reductase function
GSF67_14160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GSF67_14190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_14200	COG2813	Specifically methylates the guanine in position
GSF67_14205	COG1185	polyribonucleotide nucleotidyltransferase activity
GSF67_14210	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GSF67_14215	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GSF67_14220	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GSF67_14225	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GSF67_14225	COG3064	Membrane
GSF67_14240	COG0779	Required for maturation of 30S ribosomal subunits
GSF67_14245	COG2814	Major facilitator Superfamily
GSF67_14250	COG2951	lytic endotransglycosylase activity
GSF67_14255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GSF67_14265	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GSF67_14270	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GSF67_14285	COG2816	NAD+ diphosphatase activity
GSF67_14290	COG1605	Chorismate mutase
GSF67_14290	COG0077	Prephenate dehydratase
GSF67_14295	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GSF67_14300	COG3474	cytochrome
GSF67_14310	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GSF67_14315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GSF67_14325	COG1278	Cold shock
GSF67_14335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF67_14350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSF67_14350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GSF67_14360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GSF67_14395	COG2900	Belongs to the SlyX family
GSF67_14405	COG0484	heat shock protein binding
GSF67_14410	COG0443	Heat shock 70 kDa protein
GSF67_14425	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GSF67_14450	COG0295	cytidine deaminase activity
GSF67_14455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GSF67_14460	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GSF67_14465	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GSF67_14475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GSF67_14480	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GSF67_14485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GSF67_14495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GSF67_14500	COG1845	cytochrome c oxidase, subunit III
GSF67_14505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSF67_14515	COG0477	Major facilitator Superfamily
GSF67_14525	COG0069	glutamate synthase activity
GSF67_14525	COG0070	glutamate synthase
GSF67_14525	COG0067	glutamate synthase
GSF67_14530	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GSF67_14545	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GSF67_14555	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GSF67_14590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_14610	COG0848	biopolymer transport protein
GSF67_14620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GSF67_14640	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GSF67_14645	COG3454	Phosphonate metabolism
GSF67_14650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
GSF67_14655	COG3639	organic phosphonate transmembrane transporter activity
GSF67_14660	COG3639	organic phosphonate transmembrane transporter activity
GSF67_14665	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
GSF67_14670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GSF67_14680	COG4778	phosphonate C-P lyase system protein PhnL
GSF67_14685	COG4107	phosphonate C-P lyase system protein PhnK
GSF67_14690	COG3627	carbon phosphorus lyase activity
GSF67_14695	COG3626	phosphonate metabolism
GSF67_14700	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
GSF67_14705	COG3624	Phosphonate C-P lyase system protein PhnG
GSF67_14710	COG2188	Transcriptional regulator
GSF67_14715	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GSF67_14720	COG0837	glucose binding
GSF67_14725	COG1803	Methylglyoxal synthase
GSF67_14730	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
GSF67_14735	COG4166	transmembrane transport
GSF67_14740	COG4174	ABC transporter (Permease)
GSF67_14745	COG4239	(ABC) transporter, permease
GSF67_14760	COG4172	Belongs to the ABC transporter superfamily
GSF67_14765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_14770	COG0174	glutamine synthetase
GSF67_14775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_14780	COG3265	gluconokinase activity
GSF67_14785	COG1174	glycine betaine transport
GSF67_14790	COG1125	glycine betaine transport
GSF67_14795	COG1174	glycine betaine transport
GSF67_14800	COG1732	Glycine betaine
GSF67_14810	COG1959	2 iron, 2 sulfur cluster binding
GSF67_14815	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_14835	COG0697	spore germination
GSF67_14850	COG0791	NLP P60 protein
GSF67_14860	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GSF67_14865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GSF67_14900	COG4964	Belongs to the GSP D family
GSF67_14955	COG3422	double-strand break repair
GSF67_14960	COG3757	hydrolase, family 25
GSF67_14965	COG0697	spore germination
GSF67_14970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_15020	COG0481	GTPase activity
GSF67_15025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GSF67_15040	COG1396	sequence-specific DNA binding
GSF67_15055	COG2169	Transcriptional regulator
GSF67_15055	COG1917	Cupin 2, conserved barrel domain protein
GSF67_15060	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GSF67_15085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GSF67_15090	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GSF67_15095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GSF67_15105	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GSF67_15110	COG0072	phenylalanine-tRNA ligase activity
GSF67_15110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GSF67_15115	COG0667	Aldo Keto reductase
GSF67_15130	COG0667	Aldo Keto reductase
GSF67_15135	COG4977	sequence-specific DNA binding
GSF67_15160	COG1570	exodeoxyribonuclease VII activity
GSF67_15165	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_15175	COG1846	Transcriptional regulator
GSF67_15180	COG0697	spore germination
GSF67_15185	COG2309	aminopeptidase activity
GSF67_15190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GSF67_15195	COG1393	Belongs to the ArsC family
GSF67_15220	COG0519	Catalyzes the synthesis of GMP from XMP
GSF67_15220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GSF67_15235	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
GSF67_15265	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GSF67_15275	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GSF67_15285	COG1968	undecaprenyl-diphosphatase activity
GSF67_15305	COG0284	orotidine-5'-phosphate decarboxylase activity
GSF67_15315	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GSF67_15325	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GSF67_15330	COG0792	nuclease activity
GSF67_15345	COG1175	transmembrane transport
GSF67_15350	COG0395	ABC-type sugar transport system, permease component
GSF67_15355	COG3842	ATPase activity
GSF67_15365	COG0189	ligase activity
GSF67_15370	COG0606	chelatase, subunit chli
GSF67_15375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GSF67_15380	COG1280	lysine exporter protein (LysE YggA)
GSF67_15385	COG0756	dUTP diphosphatase activity
GSF67_15390	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GSF67_15395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GSF67_15410	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GSF67_15415	COG2226	methyltransferase
GSF67_15420	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GSF67_15425	COG1024	Enoyl-CoA hydratase
GSF67_15430	COG0268	Binds directly to 16S ribosomal RNA
GSF67_15475	COG0438	transferase activity, transferring glycosyl groups
GSF67_15495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GSF67_15525	COG4566	intracellular signal transduction
GSF67_15530	COG2197	response regulator
GSF67_15535	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GSF67_15540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_15545	COG4310	Domain of unknown function (DUF2172)
GSF67_15550	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GSF67_15560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GSF67_15565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GSF67_15570	COG2197	response regulator
GSF67_15595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_15610	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_15615	COG3842	ATPase activity
GSF67_15625	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_15630	COG1840	ABC-type Fe3 transport system, periplasmic component
GSF67_15635	COG0745	RESPONSE REGULATOR receiver
GSF67_15640	COG4191	Histidine kinase
GSF67_15640	COG0784	Response regulator, receiver
GSF67_15675	COG0596	Alpha beta hydrolase
GSF67_15680	COG0745	RESPONSE REGULATOR receiver
GSF67_15690	COG1764	response to oxidative stress
GSF67_15700	COG0596	Alpha beta hydrolase
GSF67_15720	COG0783	Belongs to the Dps family
GSF67_15725	COG0243	molybdopterin cofactor binding
GSF67_15735	COG4566	intracellular signal transduction
GSF67_15750	COG2140	Oxalate decarboxylase
GSF67_15780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GSF67_15785	COG1522	sequence-specific DNA binding
GSF67_15790	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_15795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSF67_15800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_15805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSF67_15810	COG2423	ornithine cyclodeaminase activity
GSF67_15815	COG0006	proline dipeptidase activity
GSF67_15820	COG3608	succinylglutamate desuccinylase aspartoacylase
GSF67_15825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_15830	COG0765	amino acid transport
GSF67_15835	COG0765	amino acid transport
GSF67_15840	COG1126	abc transporter atp-binding protein
GSF67_15850	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_15865	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_15870	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_15875	COG1129	ABC transporter
GSF67_15895	COG3284	Transcriptional regulator
GSF67_15900	COG1063	alcohol dehydrogenase
GSF67_15910	COG0110	maltose O-acetyltransferase activity
GSF67_15920	COG0840	transmembrane signaling receptor activity
GSF67_15925	COG1049	propionate catabolic process, 2-methylcitrate cycle
GSF67_15950	COG0488	(ABC) transporter
GSF67_15955	COG5265	(ABC) transporter
GSF67_15960	COG3181	Tripartite tricarboxylate transporter family receptor
GSF67_15965	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GSF67_15975	COG3237	CsbD-like
GSF67_15985	COG0405	Gamma-glutamyltransferase
GSF67_15995	COG0601	transmembrane transport
GSF67_16000	COG0747	negative chemotaxis
GSF67_16005	COG2186	Transcriptional regulator
GSF67_16010	COG2197	response regulator
GSF67_16015	COG3237	CsbD-like
GSF67_16035	COG0745	RESPONSE REGULATOR receiver
GSF67_16040	COG2770	Histidine kinase
GSF67_16040	COG2205	protein histidine kinase activity
GSF67_16045	COG2223	nitrite transmembrane transporter activity
GSF67_16055	COG3383	formate dehydrogenase (NAD+) activity
GSF67_16080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_16085	COG1802	Transcriptional regulator
GSF67_16090	COG4608	Belongs to the ABC transporter superfamily
GSF67_16095	COG0444	Belongs to the ABC transporter superfamily
GSF67_16100	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_16110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_16125	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_16140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_16150	COG0765	amino acid transport
GSF67_16160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_16180	COG3938	Belongs to the proline racemase family
GSF67_16190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_16200	COG0765	amino acid transport
GSF67_16220	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GSF67_16225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_16235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GSF67_16240	COG0784	Response regulator, receiver
GSF67_16255	COG0842	Transport permease protein
GSF67_16260	COG1129	ABC transporter
GSF67_16260	COG0842	Transport permease protein
GSF67_16265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_16270	COG1486	melibiose metabolic process
GSF67_16275	COG4172	Belongs to the ABC transporter superfamily
GSF67_16280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_16285	COG0601	transmembrane transport
GSF67_16290	COG0747	negative chemotaxis
GSF67_16295	COG1486	melibiose metabolic process
GSF67_16320	COG1940	carbohydrate kinase activity
GSF67_16325	COG2182	Extracellular solute-binding protein
GSF67_16330	COG1175	transmembrane transport
GSF67_16335	COG0395	ABC-type sugar transport system, permease component
GSF67_16340	COG0165	Argininosuccinate lyase
GSF67_16345	COG3842	ATPase activity
GSF67_16350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_16355	COG3119	arylsulfatase activity
GSF67_16370	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_16385	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GSF67_16415	COG1392	Phosphate transport regulator
GSF67_16420	COG0306	phosphate transporter
GSF67_16425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GSF67_16435	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GSF67_16445	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_16450	COG5001	Diguanylate cyclase
GSF67_16450	COG3300	MHYT domain
GSF67_16460	COG0747	negative chemotaxis
GSF67_16465	COG1312	Catalyzes the dehydration of D-mannonate
GSF67_16470	COG2186	Transcriptional regulator
GSF67_16475	COG0601	transmembrane transport
GSF67_16480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_16485	COG0444	Belongs to the ABC transporter superfamily
GSF67_16505	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
GSF67_16510	COG1088	dTDP-glucose 4,6-dehydratase activity
GSF67_16515	COG1091	dTDP-4-dehydrorhamnose reductase activity
GSF67_16520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GSF67_16530	COG1215	transferase activity, transferring glycosyl groups
GSF67_16540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_16570	COG1132	(ABC) transporter
GSF67_16580	COG0583	DNA-binding transcription factor activity
GSF67_16585	COG0667	Aldo Keto reductase
GSF67_16590	COG0385	Bile acid
GSF67_16620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GSF67_16625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_16635	COG1177	transmembrane transport
GSF67_16640	COG3842	ATPase activity
GSF67_16660	COG0300	oxidoreductase activity
GSF67_16680	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GSF67_16690	COG3842	ATPase activity
GSF67_16695	COG1175	transmembrane transport
GSF67_16700	COG0395	ABC-type sugar transport system, permease component
GSF67_16705	COG1609	Transcriptional regulator
GSF67_16715	COG0673	inositol 2-dehydrogenase activity
GSF67_16720	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_16735	COG1609	Transcriptional regulator
GSF67_16745	COG0183	Belongs to the thiolase family
GSF67_16750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GSF67_16760	COG1414	Transcriptional regulator
GSF67_16775	COG0583	DNA-binding transcription factor activity
GSF67_16785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GSF67_16790	COG3485	protocatechuate 3,4-dioxygenase
GSF67_16795	COG3485	protocatechuate 3,4-dioxygenase
GSF67_16805	COG0765	amino acid transport
GSF67_16810	COG0765	amino acid transport
GSF67_16815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_16820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_16825	COG1126	abc transporter atp-binding protein
GSF67_16830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF67_16835	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GSF67_16870	COG0747	negative chemotaxis
GSF67_16880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_16895	COG0683	leucine binding
GSF67_16915	COG1137	ATPase activity
GSF67_16930	COG3962	Belongs to the TPP enzyme family
GSF67_16940	COG3718	enzyme involved in inositol metabolism
GSF67_16950	COG0673	inositol 2-dehydrogenase activity
GSF67_16955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_16965	COG1609	Transcriptional regulator
GSF67_16970	COG1846	Transcriptional regulator
GSF67_16980	COG0523	cobalamin synthesis protein
GSF67_17015	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
GSF67_17040	COG0800	Aldolase
GSF67_17045	COG2954	triphosphatase activity
GSF67_17060	COG3300	MHYT domain
GSF67_17060	COG5001	Diguanylate cyclase
GSF67_17070	COG2011	ABC-type metal ion transport system permease component
GSF67_17075	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GSF67_17080	COG0778	Nitroreductase
GSF67_17100	COG2115	Belongs to the xylose isomerase family
GSF67_17105	COG1070	Carbohydrate kinase
GSF67_17110	COG1609	Transcriptional regulator
GSF67_17125	COG1309	transcriptional regulator
GSF67_17130	COG1253	flavin adenine dinucleotide binding
GSF67_17135	COG3273	potassium ion transport
GSF67_17135	COG0471	metal ion transport
GSF67_17140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GSF67_17145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GSF67_17155	COG0803	Belongs to the bacterial solute-binding protein 9 family
GSF67_17160	COG1121	(ABC) transporter
GSF67_17165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF67_17170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GSF67_17180	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_17185	COG1414	Transcriptional regulator
GSF67_17190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GSF67_17205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GSF67_17225	COG1737	Transcriptional regulator
GSF67_17230	COG1069	ribulokinase activity
GSF67_17235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_17250	COG0395	ABC-type sugar transport system, permease component
GSF67_17255	COG1175	transmembrane transport
GSF67_17265	COG2390	Transcriptional regulator
GSF67_17270	COG4172	Belongs to the ABC transporter superfamily
GSF67_17275	COG1473	amidohydrolase
GSF67_17285	COG0601	transmembrane transport
GSF67_17300	COG0693	protein deglycase activity
GSF67_17305	COG0154	amidase activity
GSF67_17310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_17325	COG0747	negative chemotaxis
GSF67_17330	COG0583	DNA-binding transcription factor activity
GSF67_17335	COG4608	Belongs to the ABC transporter superfamily
GSF67_17340	COG0444	Belongs to the ABC transporter superfamily
GSF67_17350	COG0601	transmembrane transport
GSF67_17355	COG0747	negative chemotaxis
GSF67_17370	COG1473	amidohydrolase
GSF67_17380	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GSF67_17390	COG3842	ATPase activity
GSF67_17400	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF67_17410	COG1609	Transcriptional regulator
GSF67_17415	COG0583	DNA-binding transcription factor activity
GSF67_17420	COG1960	acyl-CoA dehydrogenase activity
GSF67_17435	COG3189	MarR family transcriptional regulator
GSF67_17460	COG0673	inositol 2-dehydrogenase activity
GSF67_17470	COG1609	Transcriptional regulator
GSF67_17475	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_17480	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_17485	COG1129	ABC transporter
GSF67_17490	COG1879	ABC-type sugar transport system periplasmic component
GSF67_17505	COG1609	Transcriptional regulator
GSF67_17510	COG0673	inositol 2-dehydrogenase activity
GSF67_17520	COG1653	transport
GSF67_17525	COG1175	transmembrane transport
GSF67_17530	COG0395	ABC-type sugar transport system, permease component
GSF67_17535	COG3842	ATPase activity
GSF67_17550	COG1253	flavin adenine dinucleotide binding
GSF67_17560	COG5001	Diguanylate cyclase
GSF67_17585	COG3501	Rhs element vgr protein
GSF67_17710	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_17720	COG1879	ABC-type sugar transport system periplasmic component
GSF67_17730	COG1063	alcohol dehydrogenase
GSF67_17735	COG1309	transcriptional regulator
GSF67_17750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GSF67_17760	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_17760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_17770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_17775	COG0047	phosphoribosylformylglycinamidine synthase activity
GSF67_17795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GSF67_17800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GSF67_17815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_17820	COG2205	protein histidine kinase activity
GSF67_17820	COG0784	Response regulator, receiver
GSF67_17820	COG5002	protein histidine kinase activity
GSF67_17825	COG4191	Histidine kinase
GSF67_17830	COG0668	transmembrane transport
GSF67_17850	COG4566	intracellular signal transduction
GSF67_17860	COG0668	transmembrane transport
GSF67_17865	COG2207	Transcriptional regulator
GSF67_17875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GSF67_17890	COG2814	Major facilitator Superfamily
GSF67_17895	COG0583	DNA-binding transcription factor activity
GSF67_17900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GSF67_17905	COG0583	DNA-binding transcription factor activity
GSF67_17920	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GSF67_17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_17930	COG1126	abc transporter atp-binding protein
GSF67_17935	COG0765	amino acid transport
GSF67_17940	COG0765	amino acid transport
GSF67_17945	COG4221	oxidoreductase activity
GSF67_17955	COG0436	Aminotransferase
GSF67_17960	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_17965	COG1984	allophanate hydrolase subunit 2
GSF67_17980	COG0439	Biotin carboxylase
GSF67_17985	COG0511	ligase activity, forming carbon-carbon bonds
GSF67_17995	COG0583	DNA-binding transcription factor activity
GSF67_18010	COG1280	lysine exporter protein (LysE YggA)
GSF67_18020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GSF67_18030	COG0583	DNA-binding transcription factor activity
GSF67_18035	COG2828	Protein conserved in bacteria
GSF67_18050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_18060	COG0601	transmembrane transport
GSF67_18065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_18070	COG4172	Belongs to the ABC transporter superfamily
GSF67_18080	COG3842	ATPase activity
GSF67_18085	COG1177	transmembrane transport
GSF67_18105	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_18110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_18120	COG2267	carboxylic ester hydrolase activity
GSF67_18130	COG1454	alcohol dehydrogenase
GSF67_18135	COG1126	abc transporter atp-binding protein
GSF67_18160	COG0174	glutamine synthetase
GSF67_18165	COG0069	glutamate synthase activity
GSF67_18170	COG2218	PFAM glutamate synthase alpha subunit domain protein
GSF67_18175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GSF67_18185	COG4977	sequence-specific DNA binding
GSF67_18190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_18195	COG4311	Sarcosine oxidase, delta subunit
GSF67_18200	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_18200	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_18210	COG0300	oxidoreductase activity
GSF67_18240	COG1278	Cold shock
GSF67_18275	COG1881	PFAM PEBP family protein
GSF67_18310	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_18315	COG4172	Belongs to the ABC transporter superfamily
GSF67_18320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_18325	COG0601	transmembrane transport
GSF67_18330	COG0747	negative chemotaxis
GSF67_18345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_18390	COG0741	lytic transglycosylase activity
GSF67_18390	COG0739	heme binding
GSF67_18390	COG1196	nuclear chromosome segregation
GSF67_18395	COG0542	response to heat
GSF67_18405	COG2890	protein-(glutamine-N5) methyltransferase activity
GSF67_18410	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GSF67_18420	COG0527	aspartate kinase activity
GSF67_18430	COG0513	Belongs to the DEAD box helicase family
GSF67_18440	COG0019	diaminopimelate decarboxylase activity
GSF67_18455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF67_18465	COG3920	Histidine kinase
GSF67_18475	COG0784	Response regulator, receiver
GSF67_18490	COG1522	sequence-specific DNA binding
GSF67_18500	COG1116	anion transmembrane transporter activity
GSF67_18505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_18510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_18515	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_18520	COG0583	DNA-binding transcription factor activity
GSF67_18530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GSF67_18535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_18540	COG0189	ligase activity
GSF67_18565	COG0693	protein deglycase activity
GSF67_18595	COG3685	Protein conserved in bacteria
GSF67_18600	COG4993	Dehydrogenase
GSF67_18620	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_18625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GSF67_18645	COG0559	Belongs to the binding-protein-dependent transport system permease family
GSF67_18670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_18685	COG4608	Belongs to the ABC transporter superfamily
GSF67_18690	COG0444	Belongs to the ABC transporter superfamily
GSF67_18695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_18700	COG0601	transmembrane transport
GSF67_18705	COG0747	negative chemotaxis
GSF67_18710	COG0006	proline dipeptidase activity
GSF67_18720	COG4221	oxidoreductase activity
GSF67_18750	COG0539	negative regulation of cytoplasmic translation
GSF67_18755	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GSF67_18785	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GSF67_18790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GSF67_18820	COG1294	oxidase, subunit
GSF67_18830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GSF67_18835	COG4988	ABC transporter
GSF67_18845	COG1063	alcohol dehydrogenase
GSF67_18850	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_18855	COG2084	Dehydrogenase
GSF67_18865	COG1522	sequence-specific DNA binding
GSF67_18870	COG1794	racemase activity, acting on amino acids and derivatives
GSF67_18885	COG0058	SHG alpha-glucan phosphorylase activity
GSF67_18890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GSF67_18895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GSF67_18900	COG0297	glycogen (starch) synthase activity
GSF67_18905	COG0033	Phosphoglucomutase
GSF67_18910	COG1523	belongs to the glycosyl hydrolase 13 family
GSF67_18935	COG0446	pyridine nucleotide-disulphide oxidoreductase
GSF67_18935	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GSF67_18950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_18960	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GSF67_18980	COG1215	transferase activity, transferring glycosyl groups
GSF67_18985	COG2327	Polysaccharide pyruvyl transferase
GSF67_18990	COG0463	Glycosyl transferase, family 2
GSF67_18995	COG2244	polysaccharide biosynthetic process
GSF67_19000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF67_19005	COG2273	Hydrolase Family 16
GSF67_19010	COG0438	transferase activity, transferring glycosyl groups
GSF67_19020	COG1215	transferase activity, transferring glycosyl groups
GSF67_19025	COG1215	transferase activity, transferring glycosyl groups
GSF67_19030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSF67_19035	COG0489	protein tyrosine kinase activity
GSF67_19035	COG3206	protein involved in exopolysaccharide biosynthesis
GSF67_19040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_19045	COG4191	Histidine kinase
GSF67_19045	COG0784	Response regulator, receiver
GSF67_19055	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_19060	COG4175	Glycine betaine
GSF67_19060	COG0517	IMP dehydrogenase activity
GSF67_19075	COG0564	pseudouridine synthase activity
GSF67_19080	COG0500	methyltransferase
GSF67_19090	COG2133	pyrroloquinoline quinone binding
GSF67_19100	COG2197	response regulator
GSF67_19105	COG4585	Histidine kinase
GSF67_19115	COG1879	ABC-type sugar transport system periplasmic component
GSF67_19120	COG1129	ABC transporter
GSF67_19125	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_19135	COG3386	PFAM SMP-30 Gluconolaconase
GSF67_19140	COG2137	regulation of response to DNA damage stimulus
GSF67_19145	COG3474	cytochrome
GSF67_19155	COG1120	ATPase activity
GSF67_19170	COG4774	siderophore transport
GSF67_19175	COG0583	DNA-binding transcription factor activity
GSF67_19185	COG2194	sulfuric ester hydrolase activity
GSF67_19190	COG0745	RESPONSE REGULATOR receiver
GSF67_19195	COG0642	Histidine kinase
GSF67_19200	COG0477	Major facilitator Superfamily
GSF67_19225	COG0673	inositol 2-dehydrogenase activity
GSF67_19230	COG0697	spore germination
GSF67_19240	COG0010	Belongs to the arginase family
GSF67_19270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GSF67_19275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSF67_19280	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GSF67_19290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GSF67_19340	COG0477	Major facilitator Superfamily
GSF67_19345	COG0583	DNA-binding transcription factor activity
GSF67_19360	COG2814	Major facilitator Superfamily
GSF67_19375	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GSF67_19390	COG0346	lactoylglutathione lyase activity
GSF67_19395	COG0583	DNA-binding transcription factor activity
GSF67_19420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GSF67_19425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_19435	COG3842	ATPase activity
GSF67_19440	COG0395	ABC-type sugar transport system, permease component
GSF67_19445	COG1175	transmembrane transport
GSF67_19455	COG0673	inositol 2-dehydrogenase activity
GSF67_19460	COG0673	inositol 2-dehydrogenase activity
GSF67_19490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_19495	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_19500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_19510	COG3448	diguanylate cyclase activity
GSF67_19510	COG4175	Glycine betaine
GSF67_19520	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_19525	COG3938	Belongs to the proline racemase family
GSF67_19530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_19555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_19615	COG0402	S-adenosylhomocysteine deaminase activity
GSF67_19620	COG1228	amidohydrolase
GSF67_19625	COG2986	histidine ammonia-lyase
GSF67_19635	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GSF67_19670	COG1192	Involved in chromosome partitioning
GSF67_19675	COG1475	DNA binding
GSF67_19680	COG1414	Transcriptional regulator
GSF67_19705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GSF67_19710	COG4771	TonB-dependent receptor
GSF67_19720	COG0366	Alpha amylase catalytic
GSF67_19725	COG4770	biotin carboxylase activity
GSF67_19730	COG1984	allophanate hydrolase subunit 2
GSF67_19735	COG4336	lyase activity
GSF67_19740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_19745	COG1914	H( )-stimulated, divalent metal cation uptake system
GSF67_19750	COG1802	Transcriptional regulator
GSF67_19755	COG3707	response regulator
GSF67_19765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_19770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_19775	COG1116	anion transmembrane transporter activity
GSF67_19780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GSF67_19795	COG0243	molybdopterin cofactor binding
GSF67_19800	COG1648	precorrin-2 dehydrogenase activity
GSF67_19800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GSF67_19815	COG3842	ATPase activity
GSF67_19830	COG0395	ABC-type sugar transport system, permease component
GSF67_19845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GSF67_19860	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF67_19895	COG1129	ABC transporter
GSF67_19900	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_19910	COG0667	Aldo Keto reductase
GSF67_19915	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GSF67_19920	COG1830	Aldolase
GSF67_19925	COG1070	Carbohydrate kinase
GSF67_19935	COG1846	Transcriptional regulator
GSF67_19945	COG1304	FMN binding
GSF67_19950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_19955	COG0488	(ABC) transporter
GSF67_19970	COG2307	Protein conserved in bacteria
GSF67_19970	COG2308	Evidence 4 Homologs of previously reported genes of
GSF67_20020	COG4372	Transposase
GSF67_20030	COG2963	transposase activity
GSF67_20035	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_20065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GSF67_20125	COG1879	ABC-type sugar transport system periplasmic component
GSF67_20130	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_20140	COG1129	ABC transporter
GSF67_20145	COG2721	sulfolactate sulfo-lyase activity
GSF67_20160	COG3254	rhamnose metabolic process
GSF67_20165	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_20175	COG1335	isochorismatase
GSF67_20185	COG0667	Aldo Keto reductase
GSF67_20190	COG0583	DNA-binding transcription factor activity
GSF67_20195	COG1522	sequence-specific DNA binding
GSF67_20210	COG2814	Major facilitator Superfamily
GSF67_20215	COG2986	histidine ammonia-lyase
GSF67_20220	COG0517	IMP dehydrogenase activity
GSF67_20220	COG4175	Glycine betaine
GSF67_20225	COG4176	ABC-type proline glycine betaine transport system permease component
GSF67_20260	COG2186	Transcriptional regulator
GSF67_20265	COG1027	Aspartate ammonia-lyase
GSF67_20275	COG0252	asparaginase activity
GSF67_20285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GSF67_20290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GSF67_20295	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GSF67_20300	COG2205	protein histidine kinase activity
GSF67_20305	COG0745	RESPONSE REGULATOR receiver
GSF67_20315	COG0067	glutamate synthase
GSF67_20315	COG0070	glutamate synthase
GSF67_20315	COG0069	glutamate synthase activity
GSF67_20330	COG2205	protein histidine kinase activity
GSF67_20345	COG2951	lytic endotransglycosylase activity
GSF67_20350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GSF67_20380	COG0330	HflC and HflK could
GSF67_20385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GSF67_20390	COG0737	Belongs to the 5'-nucleotidase family
GSF67_20400	COG5310	Homospermidine synthase
GSF67_20410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GSF67_20415	COG1164	Oligoendopeptidase f
GSF67_20420	COG2204	response regulator
GSF67_20425	COG3108	Peptidase M15
GSF67_20430	COG0469	pyruvate kinase activity
GSF67_20450	COG3750	Belongs to the UPF0335 family
GSF67_20455	COG0457	Tetratricopeptide repeat
GSF67_20460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GSF67_20465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GSF67_20470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GSF67_20500	COG0483	inositol monophosphate 1-phosphatase activity
GSF67_20520	COG1132	(ABC) transporter
GSF67_20525	COG0254	rRNA binding
GSF67_20545	COG3588	fructose-bisphosphate aldolase
GSF67_20550	COG0126	phosphoglycerate kinase activity
GSF67_20590	COG1253	flavin adenine dinucleotide binding
GSF67_20600	COG1692	metallophosphoesterase
GSF67_20615	COG0217	transcriptional regulatory protein
GSF67_20620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_20625	COG0840	transmembrane signaling receptor activity
GSF67_20630	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GSF67_20635	COG0632	four-way junction helicase activity
GSF67_20640	COG2255	four-way junction helicase activity
GSF67_20650	COG2318	DinB family
GSF67_20655	COG0494	nUDIX hydrolase
GSF67_20665	COG0824	Thioesterase
GSF67_20685	COG0823	Involved in the tonB-independent uptake of proteins
GSF67_20690	COG2885	chlorophyll binding
GSF67_20700	COG0037	tRNA processing
GSF67_20705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GSF67_20710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GSF67_20725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_20740	COG0482	sulfurtransferase activity
GSF67_20750	COG0625	glutathione transferase activity
GSF67_20765	COG3118	belongs to the thioredoxin family
GSF67_20775	COG2835	tetraacyldisaccharide 4'-kinase activity
GSF67_20780	COG2373	Large extracellular alpha-helical protein
GSF67_20785	COG4953	penicillin-binding protein 1C
GSF67_20800	COG1120	ATPase activity
GSF67_20805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_20810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_20815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GSF67_20820	COG1629	transport
GSF67_20820	COG4774	siderophore transport
GSF67_20840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GSF67_20875	COG2226	methyltransferase
GSF67_20910	COG0534	Mate efflux family protein
GSF67_20920	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GSF67_20925	COG1959	2 iron, 2 sulfur cluster binding
GSF67_20935	COG1473	amidohydrolase
GSF67_20940	COG1686	Belongs to the peptidase S11 family
GSF67_20945	COG0523	cobalamin synthesis protein
GSF67_20950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GSF67_20950	COG0425	Belongs to the sulfur carrier protein TusA family
GSF67_20955	COG3034	peptidoglycan biosynthetic process
GSF67_20960	COG0825	malonyl-CoA metabolic process
GSF67_20965	COG4974	Belongs to the 'phage' integrase family
GSF67_20980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GSF67_20985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GSF67_21015	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GSF67_21020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GSF67_21035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_21040	COG2226	methyltransferase
GSF67_21045	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GSF67_21050	COG0287	Prephenate dehydrogenase
GSF67_21060	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GSF67_21080	COG2884	Cell division ATP-binding protein ftsE
GSF67_21125	COG0165	Argininosuccinate lyase
GSF67_21130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GSF67_21140	COG1250	3-hydroxyacyl-CoA dehydrogenase
GSF67_21150	COG2086	electron transfer activity
GSF67_21160	COG2096	Adenosyltransferase
GSF67_21170	COG0300	oxidoreductase activity
GSF67_21180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GSF67_21190	COG1396	sequence-specific DNA binding
GSF67_21190	COG3800	Transcriptional regulator
GSF67_21195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GSF67_21200	COG0625	glutathione transferase activity
GSF67_21210	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GSF67_21220	COG4770	biotin carboxylase activity
GSF67_21225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GSF67_21225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GSF67_21230	COG0346	lactoylglutathione lyase activity
GSF67_21245	COG4213	ABC transporter substrate-binding protein
GSF67_21250	COG4214	carbohydrate transport
GSF67_21255	COG1129	ABC transporter
GSF67_21265	COG1396	sequence-specific DNA binding
GSF67_21310	COG2273	Hydrolase Family 16
GSF67_21310	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
GSF67_21315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GSF67_21345	COG0438	transferase activity, transferring glycosyl groups
GSF67_21350	COG0297	glycogen (starch) synthase activity
GSF67_21370	COG3206	protein involved in exopolysaccharide biosynthesis
GSF67_21370	COG0489	protein tyrosine kinase activity
GSF67_21380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GSF67_21395	COG2244	polysaccharide biosynthetic process
GSF67_21405	COG0438	transferase activity, transferring glycosyl groups
GSF67_21425	COG3273	potassium ion transport
GSF67_21425	COG0471	metal ion transport
GSF67_21430	COG2376	Dihydroxyacetone kinase
GSF67_21465	COG1129	ABC transporter
GSF67_21475	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_21495	COG0246	Mannitol dehydrogenase
GSF67_21500	COG1312	Catalyzes the dehydration of D-mannonate
GSF67_21540	COG0697	spore germination
GSF67_21545	COG0653	protein targeting
GSF67_21550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GSF67_21555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GSF67_21565	COG0494	nUDIX hydrolase
GSF67_21580	COG2226	methyltransferase
GSF67_21585	COG1040	competence protein
GSF67_21595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GSF67_21605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GSF67_21625	COG4150	thiosulfate binding
GSF67_21635	COG4208	sulfate ABC transporter
GSF67_21640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GSF67_21645	COG4335	DNA alkylation repair
GSF67_21665	COG5001	Diguanylate cyclase
GSF67_21670	COG2264	protein methyltransferase activity
GSF67_21685	COG3254	rhamnose metabolic process
GSF67_21695	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_21700	COG1129	ABC transporter
GSF67_21710	COG1349	DNA-binding transcription factor activity
GSF67_21715	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_21715	COG3347	Dehydrogenase
GSF67_21720	COG4952	isomerase
GSF67_21725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GSF67_21730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GSF67_21735	COG1024	Enoyl-CoA hydratase
GSF67_21750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GSF67_21755	COG1960	acyl-CoA dehydrogenase activity
GSF67_21770	COG1960	acyl-CoA dehydrogenase activity
GSF67_21780	COG0022	dehydrogenase e1 component
GSF67_21795	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GSF67_21800	COG2391	methyltransferase activity
GSF67_21810	COG0640	Transcriptional regulator
GSF67_21815	COG3453	Protein conserved in bacteria
GSF67_21815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GSF67_21825	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_21840	COG2186	Transcriptional regulator
GSF67_21850	COG0601	transmembrane transport
GSF67_21860	COG0444	Belongs to the ABC transporter superfamily
GSF67_21865	COG4608	Belongs to the ABC transporter superfamily
GSF67_21885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_21890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_21905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_21925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_21930	COG0583	DNA-binding transcription factor activity
GSF67_21940	COG0667	Aldo Keto reductase
GSF67_21975	COG1960	acyl-CoA dehydrogenase activity
GSF67_21980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_22000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_22005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GSF67_22015	COG1959	2 iron, 2 sulfur cluster binding
GSF67_22020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_22025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_22030	COG1473	amidohydrolase
GSF67_22040	COG1126	abc transporter atp-binding protein
GSF67_22055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_22060	COG1522	sequence-specific DNA binding
GSF67_22065	COG4172	Belongs to the ABC transporter superfamily
GSF67_22070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_22075	COG0601	transmembrane transport
GSF67_22105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_22110	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_22115	COG0473	3-isopropylmalate dehydrogenase activity
GSF67_22120	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_22130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_22150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_22155	COG1120	ATPase activity
GSF67_22165	COG2226	methyltransferase
GSF67_22180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GSF67_22185	COG1120	ATPase activity
GSF67_22190	COG1595	DNA-templated transcription, initiation
GSF67_22210	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
GSF67_22215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_22220	COG0583	DNA-binding transcription factor activity
GSF67_22225	COG0601	transmembrane transport
GSF67_22250	COG1473	amidohydrolase
GSF67_22260	COG1129	ABC transporter
GSF67_22265	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_22270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GSF67_22275	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GSF67_22280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_22285	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GSF67_22300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_22310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_22315	COG2079	MmgE PrpD family protein
GSF67_22320	COG1126	abc transporter atp-binding protein
GSF67_22325	COG0765	amino acid transport
GSF67_22340	COG0280	phosphate acetyltransferase
GSF67_22340	COG0281	malic enzyme
GSF67_22345	COG0583	DNA-binding transcription factor activity
GSF67_22365	COG1175	transmembrane transport
GSF67_22370	COG0395	ABC-type sugar transport system, permease component
GSF67_22385	COG0673	inositol 2-dehydrogenase activity
GSF67_22390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GSF67_22395	COG0720	synthase
GSF67_22400	COG0602	queuosine metabolic process
GSF67_22405	COG0673	inositol 2-dehydrogenase activity
GSF67_22415	COG3842	ATPase activity
GSF67_22430	COG1653	transport
GSF67_22435	COG1609	Transcriptional regulator
GSF67_22450	COG2094	Belongs to the DNA glycosylase MPG family
GSF67_22460	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_22470	COG1376	ErfK ybiS ycfS ynhG family protein
GSF67_22470	COG1388	LysM domain
GSF67_22475	COG0840	transmembrane signaling receptor activity
GSF67_22475	COG2972	Histidine kinase
GSF67_22495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GSF67_22500	COG1596	polysaccharide export
GSF67_22505	COG3307	-O-antigen
GSF67_22540	COG2197	response regulator
GSF67_22575	COG2942	2-epimerase
GSF67_22585	COG1215	transferase activity, transferring glycosyl groups
GSF67_22605	COG1473	amidohydrolase
GSF67_22620	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_22625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GSF67_22635	COG1301	dicarboxylic acid transport
GSF67_22640	COG4191	Histidine kinase
GSF67_22645	COG2204	response regulator
GSF67_22660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_22665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GSF67_22670	COG1522	sequence-specific DNA binding
GSF67_22675	COG0351	phosphomethylpyrimidine kinase
GSF67_22680	COG0352	thiamine-phosphate diphosphorylase activity
GSF67_22685	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GSF67_22690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GSF67_22695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_22700	COG1501	Belongs to the glycosyl hydrolase 31 family
GSF67_22705	COG0395	ABC-type sugar transport system, permease component
GSF67_22710	COG1175	transmembrane transport
GSF67_22715	COG1653	transport
GSF67_22720	COG3842	ATPase activity
GSF67_22735	COG4989	oxidoreductase activity
GSF67_22790	COG0601	transmembrane transport
GSF67_22800	COG3964	amidohydrolase
GSF67_22815	COG1921	L-seryl-tRNASec selenium transferase activity
GSF67_22820	COG4172	Belongs to the ABC transporter superfamily
GSF67_22825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_22830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_22845	COG1312	Catalyzes the dehydration of D-mannonate
GSF67_22850	COG1063	alcohol dehydrogenase
GSF67_22855	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_22865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_22870	COG2186	Transcriptional regulator
GSF67_22875	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_22885	COG0850	regulation of cytokinetic process
GSF67_22890	COG2894	cell division
GSF67_22895	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GSF67_22905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_22910	COG5001	Diguanylate cyclase
GSF67_22925	COG0673	inositol 2-dehydrogenase activity
GSF67_22935	COG1653	transport
GSF67_22940	COG1175	transmembrane transport
GSF67_22945	COG0395	ABC-type sugar transport system, permease component
GSF67_22950	COG3842	ATPase activity
GSF67_22960	COG0673	inositol 2-dehydrogenase activity
GSF67_22990	COG0587	DNA-directed DNA polymerase activity
GSF67_23005	COG2186	Transcriptional regulator
GSF67_23010	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_23015	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_23020	COG1129	ABC transporter
GSF67_23025	COG1879	ABC-type sugar transport system periplasmic component
GSF67_23035	COG0129	dihydroxy-acid dehydratase activity
GSF67_23055	COG4608	Belongs to the ABC transporter superfamily
GSF67_23065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_23070	COG0601	transmembrane transport
GSF67_23075	COG0747	negative chemotaxis
GSF67_23085	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
GSF67_23090	COG5001	Diguanylate cyclase
GSF67_23100	COG3257	ureidoglycine aminohydrolase activity
GSF67_23105	COG5002	protein histidine kinase activity
GSF67_23105	COG3447	MASE1 domain protein
GSF67_23105	COG5001	Diguanylate cyclase
GSF67_23110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GSF67_23115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_23125	COG1129	ABC transporter
GSF67_23130	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_23135	COG1879	ABC-type sugar transport system periplasmic component
GSF67_23140	COG0583	DNA-binding transcription factor activity
GSF67_23165	COG3047	cAMP biosynthetic process
GSF67_23180	COG3842	ATPase activity
GSF67_23185	COG0395	ABC-type sugar transport system, permease component
GSF67_23190	COG1175	transmembrane transport
GSF67_23195	COG1653	transport
GSF67_23200	COG0523	cobalamin synthesis protein
GSF67_23215	COG0523	cobalamin synthesis protein
GSF67_23220	COG1121	(ABC) transporter
GSF67_23230	COG0803	Belongs to the bacterial solute-binding protein 9 family
GSF67_23235	COG0328	RNA-DNA hybrid ribonuclease activity
GSF67_23245	COG0626	cystathionine gamma-synthase activity
GSF67_23250	COG2182	Extracellular solute-binding protein
GSF67_23255	COG1175	transmembrane transport
GSF67_23260	COG0395	ABC-type sugar transport system, permease component
GSF67_23275	COG0395	ABC-type sugar transport system, permease component
GSF67_23280	COG1175	transmembrane transport
GSF67_23285	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
GSF67_23290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GSF67_23305	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_23310	COG1063	alcohol dehydrogenase
GSF67_23315	COG1609	Transcriptional regulator
GSF67_23330	COG2084	Dehydrogenase
GSF67_23335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_23345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_23350	COG0583	DNA-binding transcription factor activity
GSF67_23355	COG2223	nitrite transmembrane transporter activity
GSF67_23405	COG2186	Transcriptional regulator
GSF67_23410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GSF67_23415	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GSF67_23420	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_23425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_23430	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_23435	COG3618	amidohydrolase
GSF67_23440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GSF67_23460	COG1175	transmembrane transport
GSF67_23465	COG0395	ABC-type sugar transport system, permease component
GSF67_23470	COG3842	ATPase activity
GSF67_23485	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GSF67_23505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GSF67_23515	COG1278	Cold shock
GSF67_23525	COG0673	inositol 2-dehydrogenase activity
GSF67_23540	COG0673	inositol 2-dehydrogenase activity
GSF67_23545	COG1309	transcriptional regulator
GSF67_23550	COG1653	transport
GSF67_23555	COG1175	transmembrane transport
GSF67_23560	COG0395	ABC-type sugar transport system, permease component
GSF67_23565	COG3842	ATPase activity
GSF67_23570	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_23575	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_23585	COG1609	Transcriptional regulator
GSF67_23615	COG1175	transmembrane transport
GSF67_23620	COG0395	ABC-type sugar transport system, permease component
GSF67_23625	COG3842	ATPase activity
GSF67_23630	COG0395	ABC-type sugar transport system, permease component
GSF67_23640	COG1653	transport
GSF67_23675	COG3842	ATPase activity
GSF67_23685	COG1176	ABC-type spermidine putrescine transport system, permease component I
GSF67_23690	COG0395	ABC-type sugar transport system, permease component
GSF67_23700	COG1595	DNA-templated transcription, initiation
GSF67_23740	COG2233	PERMEase
GSF67_23745	COG1309	transcriptional regulator
GSF67_23750	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_23755	COG1794	racemase activity, acting on amino acids and derivatives
GSF67_23790	COG1735	metal-dependent hydrolase with the TIM-barrel fold
GSF67_23795	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_23810	COG1609	Transcriptional regulator
GSF67_23815	COG3706	GGDEF domain
GSF67_23820	COG4178	(ABC) transporter
GSF67_23825	COG0025	NhaP-type Na H and K H
GSF67_23835	COG1215	transferase activity, transferring glycosyl groups
GSF67_23880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GSF67_23885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GSF67_23895	COG1446	asparaginase
GSF67_23910	COG0747	negative chemotaxis
GSF67_23935	COG0601	transmembrane transport
GSF67_23940	COG2197	response regulator
GSF67_23970	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_23980	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GSF67_23990	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_24000	COG1653	transport
GSF67_24005	COG0395	ABC-type sugar transport system, permease component
GSF67_24010	COG4209	transmembrane transport
GSF67_24015	COG3842	ATPase activity
GSF67_24060	COG0640	Transcriptional regulator
GSF67_24100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GSF67_24110	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_24155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GSF67_24225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GSF67_24230	COG1126	abc transporter atp-binding protein
GSF67_24245	COG0640	Transcriptional regulator
GSF67_24250	COG1475	DNA binding
GSF67_24255	COG1192	Involved in chromosome partitioning
GSF67_24295	COG2207	Transcriptional regulator
GSF67_24315	COG1566	PFAM secretion protein HlyD family protein
GSF67_24325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GSF67_24375	COG3920	Histidine kinase
GSF67_24380	COG0431	NADPH-dependent FMN reductase
GSF67_24400	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_24450	COG1278	Cold shock
GSF67_24465	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GSF67_24470	COG0784	Response regulator, receiver
GSF67_24470	COG4191	Histidine kinase
GSF67_24510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GSF67_24515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_24520	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
GSF67_24525	COG2080	2 iron, 2 sulfur cluster binding
GSF67_24530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GSF67_24535	COG1309	transcriptional regulator
GSF67_24545	COG3685	Protein conserved in bacteria
GSF67_24560	COG0753	catalase activity
GSF67_24615	COG0765	amino acid transport
GSF67_24625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GSF67_24630	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_24635	COG0006	proline dipeptidase activity
GSF67_24640	COG0504	CTP synthase activity
GSF67_24650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_24660	COG2801	Transposase and inactivated derivatives
GSF67_24665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSF67_24720	COG3831	ATPase activity
GSF67_24725	COG0776	regulation of translation
GSF67_24730	COG5489	Protein of unknown function (DUF736)
GSF67_24740	COG0300	oxidoreductase activity
GSF67_24800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GSF67_24825	COG1335	isochorismatase
GSF67_24830	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GSF67_24850	COG0346	lactoylglutathione lyase activity
GSF67_24855	COG0583	DNA-binding transcription factor activity
GSF67_24860	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
GSF67_24870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GSF67_24880	COG2814	Major facilitator Superfamily
GSF67_24885	COG0583	DNA-binding transcription factor activity
GSF67_24890	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_24890	COG2010	Cytochrome c
GSF67_24895	COG2080	2 iron, 2 sulfur cluster binding
GSF67_24900	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GSF67_24900	COG2010	Cytochrome c
GSF67_24905	COG1902	pentaerythritol trinitrate reductase activity
GSF67_24915	COG0783	Belongs to the Dps family
GSF67_24925	COG4566	intracellular signal transduction
GSF67_24930	COG4566	intracellular signal transduction
GSF67_24950	COG1902	pentaerythritol trinitrate reductase activity
GSF67_24965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_24970	COG1116	anion transmembrane transporter activity
GSF67_24975	COG1309	transcriptional regulator
GSF67_24980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GSF67_25020	COG1012	belongs to the aldehyde dehydrogenase family
GSF67_25075	COG1335	isochorismatase
GSF67_25085	COG0583	DNA-binding transcription factor activity
GSF67_25130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GSF67_25155	COG1175	transmembrane transport
GSF67_25160	COG0395	ABC-type sugar transport system, permease component
GSF67_25165	COG3842	ATPase activity
GSF67_25185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GSF67_25205	COG0300	oxidoreductase activity
GSF67_25225	COG1475	DNA binding
GSF67_25285	COG0587	DNA-directed DNA polymerase activity
GSF67_25320	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_25350	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
GSF67_25360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GSF67_25365	COG3119	arylsulfatase activity
GSF67_25380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GSF67_25395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GSF67_25405	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_25445	COG1959	2 iron, 2 sulfur cluster binding
GSF67_25465	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_25520	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_25535	COG4372	Transposase
GSF67_25545	COG2963	transposase activity
GSF67_25560	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GSF67_25585	COG2132	Multicopper oxidase
GSF67_25605	COG2205	protein histidine kinase activity
GSF67_25660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_25670	COG3629	intracellular signal transduction
GSF67_25670	COG3903	Transcriptional regulator
GSF67_25705	COG0798	PFAM Bile acid sodium symporter
GSF67_25720	COG0640	Transcriptional regulator
GSF67_25755	COG0640	Transcriptional regulator
GSF67_25760	COG1475	DNA binding
GSF67_25765	COG1192	Involved in chromosome partitioning
GSF67_25775	COG4962	Type ii secretion system protein e
GSF67_25790	COG3451	type IV secretory pathway VirB4
GSF67_25795	COG5314	conjugation
GSF67_25805	COG3846	protein secretion by the type IV secretion system
GSF67_25810	COG3701	Conjugal transfer protein
GSF67_25835	COG1609	Transcriptional regulator
GSF67_25840	COG3250	beta-galactosidase activity
GSF67_25845	COG2814	Major facilitator Superfamily
GSF67_25850	COG4770	biotin carboxylase activity
GSF67_25855	COG0395	ABC-type sugar transport system, permease component
GSF67_25860	COG1175	transmembrane transport
GSF67_25875	COG0346	lactoylglutathione lyase activity
GSF67_25880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GSF67_25885	COG0277	FAD linked oxidase domain protein
GSF67_25900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GSF67_25935	COG2086	electron transfer activity
GSF67_25950	COG0840	transmembrane signaling receptor activity
GSF67_25985	COG3842	ATPase activity
GSF67_25990	COG1177	transmembrane transport
GSF67_25995	COG0596	Alpha beta hydrolase
GSF67_26000	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSF67_26005	COG0022	dehydrogenase e1 component
GSF67_26010	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_26045	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_26055	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_26060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GSF67_26065	COG0022	dehydrogenase e1 component
GSF67_26075	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_26095	COG4336	lyase activity
GSF67_26110	COG1129	ABC transporter
GSF67_26115	COG1172	Belongs to the binding-protein-dependent transport system permease family
GSF67_26120	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_26125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GSF67_26130	COG4770	biotin carboxylase activity
GSF67_26135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GSF67_26180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GSF67_26185	COG2181	nitrate reductase activity
GSF67_26185	COG0247	lactate metabolic process
GSF67_26190	COG0583	DNA-binding transcription factor activity
GSF67_26215	COG2186	Transcriptional regulator
GSF67_26220	COG1414	Transcriptional regulator
GSF67_26230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GSF67_26255	COG2801	Transposase and inactivated derivatives
GSF67_26260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GSF67_26280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GSF67_26295	COG3158	transport of potassium into the cell
GSF67_26300	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_26305	COG1414	Transcriptional regulator
GSF67_26310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GSF67_26315	COG3842	ATPase activity
GSF67_26320	COG0395	ABC-type sugar transport system, permease component
GSF67_26325	COG1175	transmembrane transport
GSF67_26335	COG4948	Mandelate Racemase Muconate Lactonizing
GSF67_26340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GSF67_26345	COG3734	2-keto-3-deoxy-galactonokinase
GSF67_26380	COG0071	Belongs to the small heat shock protein (HSP20) family
GSF67_26385	COG3831	ATPase activity
GSF67_26395	COG0596	Alpha beta hydrolase
GSF67_26400	COG1902	pentaerythritol trinitrate reductase activity
GSF67_26405	COG4221	oxidoreductase activity
GSF67_26420	COG2972	Histidine kinase
GSF67_26420	COG0840	transmembrane signaling receptor activity
GSF67_26445	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_26455	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_26460	COG0673	inositol 2-dehydrogenase activity
GSF67_26465	COG1082	Xylose isomerase domain protein TIM barrel
GSF67_26470	COG1609	Transcriptional regulator
GSF67_26495	COG0534	Mate efflux family protein
GSF67_26515	COG2072	flavoprotein involved in K transport
GSF67_26520	COG3842	ATPase activity
GSF67_26525	COG1177	transmembrane transport
GSF67_26540	COG0583	DNA-binding transcription factor activity
GSF67_26605	COG0297	glycogen (starch) synthase activity
GSF67_26610	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GSF67_26640	COG3685	Protein conserved in bacteria
GSF67_26650	COG1028	Short-chain dehydrogenase reductase Sdr
GSF67_26675	COG2378	regulation of single-species biofilm formation
GSF67_26690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GSF67_26695	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GSF67_26720	COG0395	ABC-type sugar transport system, permease component
GSF67_26725	COG3547	Transposase (IS116 IS110 IS902 family)
GSF67_26730	COG3177	Filamentation induced by cAMP protein fic
GSF67_26740	COG2020	methyltransferase activity
GSF67_26745	COG4644	lycopene metabolic process
GSF67_26765	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
GSF67_26770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins