locus-tag	class	description
BSY240_1000	COG0081	regulation of translation
BSY240_1001	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSY240_1008	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY240_1012	COG3769	mannosylglycerate metabolic process
BSY240_1013	COG1215	transferase activity, transferring glycosyl groups
BSY240_1016	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSY240_1021	COG1388	LysM domain
BSY240_1021	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSY240_1022	COG1530	ribonuclease E activity
BSY240_1024	COG0436	Aminotransferase
BSY240_1026	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSY240_1027	COG0511	ligase activity, forming carbon-carbon bonds
BSY240_1029	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSY240_103	COG3256	nitric oxide reductase
BSY240_1030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY240_1031	COG0243	molybdopterin cofactor binding
BSY240_1036	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY240_104	COG0714	Associated with various cellular activities
BSY240_1045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY240_1046	COG0454	-acetyltransferase
BSY240_1048	COG3811	Belongs to the UPF0386 family
BSY240_1052	COG0154	amidase activity
BSY240_1053	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY240_1054	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSY240_1055	COG2824	Alkylphosphonate utilization operon protein PhnA
BSY240_1057	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSY240_1058	COG1960	acyl-CoA dehydrogenase activity
BSY240_106	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY240_1060	COG0540	Belongs to the ATCase OTCase family
BSY240_1061	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY240_1062	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSY240_1064	COG0758	DNA mediated transformation
BSY240_1065	COG1754	DNA topoisomerase type I activity
BSY240_1065	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSY240_1068	COG0477	Major facilitator Superfamily
BSY240_1069	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSY240_1070	COG3706	GGDEF domain
BSY240_1070	COG0745	RESPONSE REGULATOR receiver
BSY240_1071	COG0784	Response regulator, receiver
BSY240_1074	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY240_1077	COG0587	DNA-directed DNA polymerase activity
BSY240_1078	COG1136	(ABC) transporter
BSY240_1080	COG0442	prolyl-tRNA aminoacylation
BSY240_1085	COG1007	ATP synthesis coupled electron transport
BSY240_1088	COG0713	ATP synthesis coupled electron transport
BSY240_1090	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY240_1091	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSY240_1093	COG3743	rRNA binding
BSY240_1093	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY240_1094	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSY240_1095	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BSY240_1097	COG0649	NAD binding
BSY240_1098	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY240_1099	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY240_1100	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY240_1106	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_1108	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSY240_1111	COG0667	Aldo Keto reductase
BSY240_1113	COG0697	spore germination
BSY240_1115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSY240_1116	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSY240_1117	COG0740	serine-type endopeptidase activity
BSY240_1118	COG5001	Diguanylate cyclase
BSY240_1119	COG2378	regulation of single-species biofilm formation
BSY240_112	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY240_1125	COG1832	CoA-binding protein
BSY240_1127	COG1832	CoA-binding protein
BSY240_1129	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSY240_1130	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSY240_1131	COG0010	Belongs to the arginase family
BSY240_1132	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSY240_1133	COG3384	dioxygenase
BSY240_1134	COG1612	heme a metabolic process
BSY240_1139	COG0297	glycogen (starch) synthase activity
BSY240_114	COG3005	denitrification pathway
BSY240_1148	COG0776	regulation of translation
BSY240_1149	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSY240_1150	COG0416	fatty acid biosynthetic process
BSY240_1154	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSY240_1155	COG2814	Major facilitator Superfamily
BSY240_1156	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY240_1157	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSY240_1159	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY240_1159	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY240_1160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSY240_1161	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSY240_1166	COG0113	porphobilinogen synthase activity
BSY240_1168	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BSY240_1170	COG3300	MHYT domain
BSY240_1170	COG5001	Diguanylate cyclase
BSY240_1172	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSY240_1174	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSY240_1176	COG2963	transposase activity
BSY240_1185	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSY240_1193	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSY240_1195	COG0628	permease
BSY240_1196	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSY240_1197	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSY240_1199	COG1132	(ABC) transporter
BSY240_1200	COG0243	molybdopterin cofactor binding
BSY240_1201	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSY240_1205	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_1206	COG0322	excinuclease ABC activity
BSY240_1207	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSY240_1209	COG0314	molybdopterin synthase activity
BSY240_1210	COG0105	UTP biosynthetic process
BSY240_1216	COG0488	(ABC) transporter
BSY240_1217	COG0840	transmembrane signaling receptor activity
BSY240_1217	COG2972	Histidine kinase
BSY240_1219	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY240_122	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY240_1222	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSY240_1224	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSY240_1225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY240_1226	COG0840	transmembrane signaling receptor activity
BSY240_1227	COG0583	DNA-binding transcription factor activity
BSY240_1229	COG3119	arylsulfatase activity
BSY240_1230	COG0194	GDP metabolic process
BSY240_1231	COG1561	YicC-like family, N-terminal region
BSY240_1232	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSY240_1233	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSY240_1234	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY240_1236	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSY240_1237	COG0667	Aldo Keto reductase
BSY240_1239	COG0360	Binds together with S18 to 16S ribosomal RNA
BSY240_124	COG0697	spore germination
BSY240_1240	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSY240_1242	COG0359	binds to the 23S rRNA
BSY240_1247	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSY240_1248	COG3609	addiction module antidote protein, CC2985 family
BSY240_125	COG0583	DNA-binding transcription factor activity
BSY240_1251	COG1286	toxin biosynthetic process
BSY240_1252	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSY240_1253	COG4221	oxidoreductase activity
BSY240_1254	COG3706	GGDEF domain
BSY240_1257	COG0215	cysteine-tRNA ligase activity
BSY240_1264	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY240_1265	COG2962	Rard protein
BSY240_1268	COG5265	(ABC) transporter
BSY240_1269	COG3706	GGDEF domain
BSY240_1270	COG0688	phosphatidylethanolamine metabolic process
BSY240_1271	COG1183	phosphatidylcholine synthase activity
BSY240_1278	COG0354	folic acid binding
BSY240_1279	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BSY240_128	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY240_1282	COG0668	transmembrane transport
BSY240_1285	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSY240_1286	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSY240_1288	COG1418	mRNA catabolic process
BSY240_1291	COG1381	Involved in DNA repair and RecF pathway recombination
BSY240_1294	COG3180	Ammonia monooxygenase
BSY240_1295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSY240_1296	COG0571	ribonuclease III activity
BSY240_1297	COG0681	Belongs to the peptidase S26 family
BSY240_1298	COG0736	holo-[acyl-carrier-protein] synthase activity
BSY240_13	COG1116	anion transmembrane transporter activity
BSY240_1302	COG1758	RNA polymerase activity
BSY240_1304	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSY240_1304	COG2169	Transcriptional regulator
BSY240_1307	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSY240_1309	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_1310	COG2311	Membrane
BSY240_1312	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_1313	COG0741	lytic transglycosylase activity
BSY240_1315	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BSY240_1317	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BSY240_132	COG1802	Transcriptional regulator
BSY240_1322	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY240_1327	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSY240_133	COG0411	ABC transporter
BSY240_1335	COG0174	glutamine synthetase
BSY240_1337	COG0601	transmembrane transport
BSY240_1338	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY240_1339	COG4172	Belongs to the ABC transporter superfamily
BSY240_1342	COG2814	Major facilitator Superfamily
BSY240_1344	COG1522	sequence-specific DNA binding
BSY240_1346	COG1733	regulation of RNA biosynthetic process
BSY240_1347	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_135	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY240_1350	COG2084	Dehydrogenase
BSY240_1352	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_1355	COG0443	Heat shock 70 kDa protein
BSY240_1362	COG0840	transmembrane signaling receptor activity
BSY240_1362	COG3290	protein histidine kinase activity
BSY240_1363	COG0308	aminopeptidase N
BSY240_1364	COG2202	Pas domain
BSY240_1364	COG2205	protein histidine kinase activity
BSY240_1365	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSY240_1366	COG2205	protein histidine kinase activity
BSY240_1367	COG0745	RESPONSE REGULATOR receiver
BSY240_1368	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY240_1371	COG3088	subunit of a heme lyase
BSY240_1372	COG1138	Cytochrome C-type biogenesis protein
BSY240_1373	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BSY240_1374	COG4235	cytochrome complex assembly
BSY240_1376	COG2205	protein histidine kinase activity
BSY240_1377	COG0745	RESPONSE REGULATOR receiver
BSY240_1402	COG4695	Portal protein
BSY240_1412	COG3706	GGDEF domain
BSY240_1413	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSY240_1415	COG0789	Transcriptional regulator
BSY240_1417	COG3077	Addiction module antitoxin, RelB DinJ family
BSY240_1419	COG2983	Belongs to the UPF0260 family
BSY240_1420	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSY240_1421	COG3706	GGDEF domain
BSY240_1422	COG3706	GGDEF domain
BSY240_1425	COG2264	protein methyltransferase activity
BSY240_1445	COG2205	protein histidine kinase activity
BSY240_1447	COG2166	iron-sulfur cluster assembly
BSY240_1450	COG4957	zinc ion binding
BSY240_1451	COG1320	monovalent cation:proton antiporter activity
BSY240_1452	COG2212	antiporter activity
BSY240_1453	COG1863	multisubunit Na H antiporter MnhE subunit
BSY240_1455	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY240_1458	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY240_146	COG2968	Membrane
BSY240_1462	COG0514	ATP-dependent DNA helicase (RecQ)
BSY240_1467	COG2130	NADP-dependent
BSY240_1471	COG1272	protein, Hemolysin III
BSY240_1472	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BSY240_1473	COG0840	transmembrane signaling receptor activity
BSY240_1477	COG1129	ABC transporter
BSY240_1478	COG4214	carbohydrate transport
BSY240_1479	COG1879	ABC-type sugar transport system periplasmic component
BSY240_148	COG0646	methionine synthase
BSY240_148	COG1410	methionine synthase
BSY240_1485	COG1238	metal cluster binding
BSY240_1491	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_1496	COG0433	COG0433 Predicted ATPase
BSY240_1498	COG1742	UPF0060 membrane protein
BSY240_1502	COG3239	Fatty acid desaturase
BSY240_1504	COG1278	Cold shock
BSY240_1505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSY240_1512	COG1764	response to oxidative stress
BSY240_1513	COG1846	Transcriptional regulator
BSY240_1514	COG4325	translation initiation factor activity
BSY240_1518	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_1520	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_1522	COG0477	Major facilitator Superfamily
BSY240_1540	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BSY240_1541	COG1309	transcriptional regulator
BSY240_1542	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_1543	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSY240_1545	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSY240_1545	COG0392	lysyltransferase activity
BSY240_155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BSY240_1558	COG1959	2 iron, 2 sulfur cluster binding
BSY240_1559	COG0175	sulfate reduction
BSY240_1560	COG0175	sulfate reduction
BSY240_1561	COG2895	sulfate adenylyltransferase (ATP) activity
BSY240_1564	COG0840	transmembrane signaling receptor activity
BSY240_1565	COG1609	Transcriptional regulator
BSY240_1571	COG1595	DNA-templated transcription, initiation
BSY240_1575	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_1576	COG4605	iron ion homeostasis
BSY240_1577	COG4604	ABC transporter, ATP-binding protein
BSY240_1579	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BSY240_1583	COG1132	(ABC) transporter
BSY240_1585	COG0693	protein deglycase activity
BSY240_1593	COG0864	Transcriptional regulator
BSY240_1595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY240_1595	COG0574	Belongs to the PEP-utilizing enzyme family
BSY240_1597	COG0574	Belongs to the PEP-utilizing enzyme family
BSY240_1597	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY240_1598	COG2514	catechol 2,3-dioxygenase activity
BSY240_16	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_1600	COG0738	Major facilitator superfamily
BSY240_1602	COG1196	nuclear chromosome segregation
BSY240_1610	COG0659	secondary active sulfate transmembrane transporter activity
BSY240_1612	COG1194	a g-specific adenine glycosylase
BSY240_1614	COG2885	chlorophyll binding
BSY240_1615	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BSY240_1618	COG1942	4-Oxalocrotonate Tautomerase
BSY240_162	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY240_1620	COG2070	2-Nitropropane dioxygenase
BSY240_1622	COG1268	BioY protein
BSY240_1626	COG3609	addiction module antidote protein, CC2985 family
BSY240_163	COG0174	glutamine synthetase
BSY240_1632	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY240_1633	COG1597	lipid kinase activity
BSY240_1638	COG0612	Peptidase, M16
BSY240_1639	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSY240_1640	COG5001	Diguanylate cyclase
BSY240_1641	COG1280	lysine exporter protein (LysE YggA)
BSY240_1644	COG1678	Uncharacterized ACR, COG1678
BSY240_1646	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSY240_1646	COG0678	peroxiredoxin activity
BSY240_1648	COG0328	RNA-DNA hybrid ribonuclease activity
BSY240_1649	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSY240_1651	COG5001	Diguanylate cyclase
BSY240_1651	COG3300	MHYT domain
BSY240_1653	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSY240_1655	COG3346	SURF1 family
BSY240_1658	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSY240_1660	COG0109	protoheme IX farnesyltransferase activity
BSY240_1661	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY240_1664	COG0312	modulator of DNA gyrase
BSY240_1666	COG1686	Belongs to the peptidase S11 family
BSY240_1667	COG0789	Transcriptional regulator
BSY240_1668	COG2814	Major facilitator Superfamily
BSY240_167	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_1670	COG0259	pyridoxamine-phosphate oxidase activity
BSY240_1672	COG0484	heat shock protein binding
BSY240_1673	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSY240_1677	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSY240_1678	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY240_1678	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY240_1682	COG3214	Protein conserved in bacteria
BSY240_1683	COG1122	ATPase activity
BSY240_1684	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BSY240_1685	COG1268	BioY protein
BSY240_1690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSY240_1694	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSY240_1695	COG1741	Belongs to the pirin family
BSY240_1696	COG2610	gluconate transmembrane transporter activity
BSY240_1701	COG1522	sequence-specific DNA binding
BSY240_1704	COG4215	(ABC) transporter
BSY240_1707	COG2040	homocysteine
BSY240_1709	COG1722	exodeoxyribonuclease VII activity
BSY240_1710	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSY240_1714	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSY240_1719	COG1960	acyl-CoA dehydrogenase activity
BSY240_172	COG0697	spore germination
BSY240_1721	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BSY240_1722	COG2894	cell division
BSY240_1723	COG0850	regulation of cytokinetic process
BSY240_1727	COG4638	Rieske (2fe-2S)
BSY240_1730	COG0009	L-threonylcarbamoyladenylate synthase
BSY240_1732	COG2005	Transcriptional regulator
BSY240_1732	COG3585	molybdate ion transport
BSY240_1733	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BSY240_1734	COG4149	molybdate abc transporter
BSY240_1735	COG0725	ABC transporter, periplasmic molybdate-binding protein
BSY240_1739	COG3713	MltA-interacting MipA family protein
BSY240_174	COG0028	Belongs to the TPP enzyme family
BSY240_1740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSY240_1744	COG0789	Transcriptional regulator
BSY240_175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY240_1750	COG2010	Cytochrome c
BSY240_1751	COG3909	cytochrome
BSY240_1754	COG2514	catechol 2,3-dioxygenase activity
BSY240_1757	COG2183	response to ionizing radiation
BSY240_1758	COG0151	Belongs to the GarS family
BSY240_1760	COG0840	transmembrane signaling receptor activity
BSY240_1761	COG1683	Conserved Protein
BSY240_1763	COG3609	addiction module antidote protein, CC2985 family
BSY240_1764	COG0751	glycine-tRNA ligase activity
BSY240_1766	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSY240_1767	COG1704	LemA family
BSY240_1768	COG2205	protein histidine kinase activity
BSY240_1768	COG2202	Pas domain
BSY240_1770	COG0752	glycyl-tRNA synthetase alpha subunit
BSY240_1771	COG2202	Pas domain
BSY240_1771	COG3920	Histidine kinase
BSY240_1776	COG0142	geranyltranstransferase activity
BSY240_1778	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSY240_1779	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSY240_178	COG0840	transmembrane signaling receptor activity
BSY240_1782	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSY240_1783	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY240_1784	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY240_1786	COG0356	it plays a direct role in the translocation of protons across the membrane
BSY240_1790	COG3158	transport of potassium into the cell
BSY240_1791	COG0598	Magnesium transport protein CorA
BSY240_1792	COG0489	protein tyrosine kinase activity
BSY240_1793	COG2197	response regulator
BSY240_1794	COG3386	PFAM SMP-30 Gluconolaconase
BSY240_1796	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY240_1796	COG1902	pentaerythritol trinitrate reductase activity
BSY240_1797	COG5598	trimethylamine methyltransferase
BSY240_1798	COG0583	DNA-binding transcription factor activity
BSY240_1799	COG5001	Diguanylate cyclase
BSY240_1799	COG3300	MHYT domain
BSY240_1800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_1800	COG2205	protein histidine kinase activity
BSY240_1801	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSY240_1803	COG1663	tetraacyldisaccharide 4'-kinase activity
BSY240_1805	COG1519	Transferase
BSY240_1808	COG0312	modulator of DNA gyrase
BSY240_1810	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSY240_1811	COG0742	ribosomal rna small subunit methyltransferase
BSY240_1812	COG1187	pseudouridine synthase activity
BSY240_1813	COG0590	tRNA wobble adenosine to inosine editing
BSY240_1817	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSY240_1823	COG0196	riboflavin kinase activity
BSY240_1826	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSY240_1827	COG0459	protein refolding
BSY240_1829	COG0625	glutathione transferase activity
BSY240_1830	COG2259	Doxx family
BSY240_1831	COG4106	trans-aconitate 2-methyltransferase activity
BSY240_1832	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSY240_1833	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSY240_1834	COG0124	histidyl-tRNA synthetase
BSY240_1841	COG2818	Glycosylase
BSY240_1842	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_1843	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_1845	COG0247	lactate metabolic process
BSY240_1847	COG0277	FAD linked oxidase domain protein
BSY240_1848	COG0277	FAD linked oxidase domain protein
BSY240_1849	COG0583	DNA-binding transcription factor activity
BSY240_185	COG5001	Diguanylate cyclase
BSY240_185	COG3300	MHYT domain
BSY240_1853	COG0247	lactate metabolic process
BSY240_1854	COG1139	Iron-sulfur cluster binding protein
BSY240_1856	COG0438	transferase activity, transferring glycosyl groups
BSY240_1857	COG0561	phosphatase activity
BSY240_1859	COG0306	phosphate transporter
BSY240_1863	COG0840	transmembrane signaling receptor activity
BSY240_1865	COG0583	DNA-binding transcription factor activity
BSY240_1876	COG0477	Major facilitator Superfamily
BSY240_1878	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSY240_1879	COG0248	Ppx GppA phosphatase
BSY240_1882	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY240_1890	COG0583	DNA-binding transcription factor activity
BSY240_1893	COG3590	peptidase
BSY240_1898	COG2194	sulfuric ester hydrolase activity
BSY240_190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BSY240_1901	COG0745	RESPONSE REGULATOR receiver
BSY240_1903	COG2188	Transcriptional regulator
BSY240_1904	COG3454	Phosphonate metabolism
BSY240_1906	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSY240_1907	COG3639	organic phosphonate transmembrane transporter activity
BSY240_1908	COG0642	Histidine kinase
BSY240_191	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSY240_1912	COG2828	Protein conserved in bacteria
BSY240_1913	COG2814	Major facilitator Superfamily
BSY240_1924	COG2205	protein histidine kinase activity
BSY240_1925	COG0745	RESPONSE REGULATOR receiver
BSY240_1927	COG1253	flavin adenine dinucleotide binding
BSY240_1928	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY240_1930	COG0668	transmembrane transport
BSY240_1932	COG3842	ATPase activity
BSY240_1934	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY240_1935	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY240_1936	COG0745	RESPONSE REGULATOR receiver
BSY240_1938	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSY240_1938	COG1648	precorrin-2 dehydrogenase activity
BSY240_1939	COG0243	molybdopterin cofactor binding
BSY240_194	COG2001	Belongs to the MraZ family
BSY240_1941	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSY240_1942	COG1116	anion transmembrane transporter activity
BSY240_1943	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY240_1944	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY240_1945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY240_1946	COG3707	response regulator
BSY240_1947	COG1136	(ABC) transporter
BSY240_195	COG0275	rRNA processing
BSY240_1959	COG0662	Cupin 2, conserved barrel domain protein
BSY240_1962	COG1595	DNA-templated transcription, initiation
BSY240_1963	COG1309	transcriptional regulator
BSY240_1966	COG1070	Carbohydrate kinase
BSY240_1968	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BSY240_1969	COG0667	Aldo Keto reductase
BSY240_1970	COG2390	Transcriptional regulator
BSY240_1971	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_1972	COG1129	ABC transporter
BSY240_1977	COG3920	Histidine kinase
BSY240_198	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSY240_1980	COG0589	response to stress
BSY240_1981	COG0659	secondary active sulfate transmembrane transporter activity
BSY240_1982	COG1278	Cold shock
BSY240_1985	COG4191	Histidine kinase
BSY240_1985	COG0784	Response regulator, receiver
BSY240_1988	COG0438	transferase activity, transferring glycosyl groups
BSY240_1999	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY240_200	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSY240_2003	COG1320	monovalent cation:proton antiporter activity
BSY240_2004	COG4191	Histidine kinase
BSY240_2005	COG2204	response regulator
BSY240_2007	COG4771	TonB-dependent receptor
BSY240_201	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSY240_2011	COG1320	monovalent cation:proton antiporter activity
BSY240_2012	COG2212	antiporter activity
BSY240_2013	COG1863	multisubunit Na H antiporter MnhE subunit
BSY240_2014	COG0651	ATP synthesis coupled electron transport
BSY240_2015	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY240_2016	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY240_2016	COG2111	Na H antiporter
BSY240_2018	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSY240_2019	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSY240_2021	COG1653	transport
BSY240_2022	COG1175	transmembrane transport
BSY240_2023	COG0395	ABC-type sugar transport system, permease component
BSY240_2024	COG3842	ATPase activity
BSY240_2025	COG0483	inositol monophosphate 1-phosphatase activity
BSY240_2027	COG3842	ATPase activity
BSY240_2028	COG3833	ABC-type maltose transport systems, permease component
BSY240_2029	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_203	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSY240_2031	COG1609	Transcriptional regulator
BSY240_2034	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY240_2037	COG4774	siderophore transport
BSY240_2038	COG4592	Periplasmic binding protein
BSY240_2039	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_204	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSY240_2040	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_2041	COG1120	ATPase activity
BSY240_2045	COG2832	Protein of unknown function (DUF454)
BSY240_2046	COG5001	Diguanylate cyclase
BSY240_2047	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_2048	COG0174	glutamine synthetase
BSY240_2049	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSY240_2051	COG3265	gluconokinase activity
BSY240_2053	COG1959	2 iron, 2 sulfur cluster binding
BSY240_2054	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY240_2055	COG4783	chaperone-mediated protein folding
BSY240_2056	COG4269	membrane
BSY240_206	COG3706	GGDEF domain
BSY240_2061	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSY240_2066	COG2205	protein histidine kinase activity
BSY240_2068	COG1178	ABC-type Fe3 transport system permease component
BSY240_2069	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY240_207	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSY240_2072	COG1177	transmembrane transport
BSY240_2073	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_2074	COG3842	ATPase activity
BSY240_2075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BSY240_2077	COG2224	Isocitrate lyase
BSY240_208	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSY240_2081	COG0840	transmembrane signaling receptor activity
BSY240_2081	COG2972	Histidine kinase
BSY240_2083	COG2081	HI0933 family
BSY240_2085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_2086	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSY240_2087	COG0363	glucosamine-6-phosphate deaminase activity
BSY240_2088	COG0129	dihydroxy-acid dehydratase activity
BSY240_209	COG0849	cell division
BSY240_2091	COG1595	DNA-templated transcription, initiation
BSY240_2094	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_2096	COG3842	ATPase activity
BSY240_2097	COG0366	Alpha amylase catalytic
BSY240_2098	COG0395	ABC-type sugar transport system, permease component
BSY240_2099	COG1175	transmembrane transport
BSY240_21	COG4176	ABC-type proline glycine betaine transport system permease component
BSY240_210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSY240_2100	COG1653	transport
BSY240_2101	COG1609	Transcriptional regulator
BSY240_2102	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSY240_2109	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSY240_2110	COG4794	Type iii secretion
BSY240_2111	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BSY240_2112	COG5443	negative regulation of bacterial-type flagellum assembly
BSY240_2115	COG4786	Flagellar basal body rod
BSY240_2115	COG1256	bacterial-type flagellum assembly
BSY240_2116	COG1749	Flagellar hook protein flgE
BSY240_212	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSY240_2121	COG1360	Flagellar Motor Protein
BSY240_2123	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY240_2124	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY240_2127	COG1338	Plays a role in the flagellum-specific transport system
BSY240_2129	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BSY240_213	COG0497	DNA recombination
BSY240_2131	COG1706	bacterial-type flagellum-dependent cell motility
BSY240_2132	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BSY240_2133	COG4786	Flagellar basal body rod
BSY240_2134	COG1677	Flagellar hook-basal body complex protein FliE
BSY240_2135	COG1558	bacterial-type flagellum-dependent cell motility
BSY240_2136	COG1815	bacterial-type flagellum-dependent cell motility
BSY240_2138	COG1157	protein secretion by the type III secretion system
BSY240_2139	COG4786	Flagellar basal body rod
BSY240_214	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY240_2140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSY240_2141	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY240_2142	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY240_2143	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY240_2144	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BSY240_2147	COG2771	luxR family
BSY240_2148	COG1766	The M ring may be actively involved in energy transduction
BSY240_2150	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BSY240_2151	COG0745	RESPONSE REGULATOR receiver
BSY240_2152	COG2201	protein-glutamate methylesterase activity
BSY240_2153	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSY240_2154	COG0835	chemotaxis
BSY240_2155	COG2198	Histidine kinase
BSY240_2155	COG0643	Histidine kinase
BSY240_2158	COG0840	transmembrane signaling receptor activity
BSY240_216	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY240_2161	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BSY240_2163	COG0297	glycogen (starch) synthase activity
BSY240_217	COG2199	diguanylate cyclase activity
BSY240_2175	COG1607	acyl-coa hydrolase
BSY240_2176	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_2177	COG1802	Transcriptional regulator
BSY240_2178	COG1914	H( )-stimulated, divalent metal cation uptake system
BSY240_2179	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSY240_2180	COG4336	lyase activity
BSY240_2181	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BSY240_2182	COG4770	biotin carboxylase activity
BSY240_2184	COG1024	Enoyl-CoA hydratase
BSY240_2187	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_2194	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY240_2198	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY240_2205	COG2274	protein secretion by the type I secretion system
BSY240_2208	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY240_2209	COG2186	Transcriptional regulator
BSY240_2210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_2211	COG4948	Mandelate Racemase Muconate Lactonizing
BSY240_2212	COG3618	amidohydrolase
BSY240_2213	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_2216	COG2423	ornithine cyclodeaminase activity
BSY240_2218	COG2137	regulation of response to DNA damage stimulus
BSY240_2220	COG4585	Histidine kinase
BSY240_2221	COG1879	ABC-type sugar transport system periplasmic component
BSY240_2222	COG1129	ABC transporter
BSY240_2223	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_2227	COG1733	regulation of RNA biosynthetic process
BSY240_2231	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY240_2232	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_2234	COG2226	methyltransferase
BSY240_2236	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_2237	COG1120	ATPase activity
BSY240_2239	COG1448	Aminotransferase
BSY240_2240	COG1522	sequence-specific DNA binding
BSY240_2241	COG4608	Belongs to the ABC transporter superfamily
BSY240_2242	COG0444	Belongs to the ABC transporter superfamily
BSY240_2243	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY240_2244	COG0601	transmembrane transport
BSY240_2245	COG0747	negative chemotaxis
BSY240_225	COG0835	chemotaxis
BSY240_2256	COG2390	Transcriptional regulator
BSY240_2257	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_2257	COG3347	Dehydrogenase
BSY240_2259	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_226	COG0840	transmembrane signaling receptor activity
BSY240_226	COG2972	Histidine kinase
BSY240_2260	COG1129	ABC transporter
BSY240_2261	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
BSY240_2262	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BSY240_2263	COG3959	Transketolase, thiamine diphosphate binding domain
BSY240_2264	COG3958	Transketolase
BSY240_2265	COG1850	ribulose-bisphosphate carboxylase activity
BSY240_2271	COG1525	nuclease
BSY240_2273	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY240_2276	COG0583	DNA-binding transcription factor activity
BSY240_2287	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSY240_2288	COG0424	maF-like protein
BSY240_2289	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSY240_229	COG1999	signal sequence binding
BSY240_2291	COG5328	Belongs to the UPF0262 family
BSY240_2292	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSY240_2294	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSY240_2299	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSY240_230	COG2264	protein methyltransferase activity
BSY240_2300	COG0842	Transport permease protein
BSY240_2301	COG0842	Transport permease protein
BSY240_2301	COG1129	ABC transporter
BSY240_2302	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY240_2305	COG1970	mechanosensitive ion channel activity
BSY240_2306	COG0784	Response regulator, receiver
BSY240_2306	COG2205	protein histidine kinase activity
BSY240_2306	COG2198	Histidine kinase
BSY240_2309	COG0584	glycerophosphoryl diester phosphodiesterase
BSY240_2310	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY240_2310	COG1024	Enoyl-CoA hydratase
BSY240_2312	COG0183	Belongs to the thiolase family
BSY240_2313	COG1960	acyl-CoA dehydrogenase activity
BSY240_2315	COG0730	response to heat
BSY240_2318	COG1201	RNA secondary structure unwinding
BSY240_2323	COG0167	dihydroorotate dehydrogenase activity
BSY240_2324	COG0534	Mate efflux family protein
BSY240_2335	COG0717	Belongs to the dCTP deaminase family
BSY240_2337	COG2967	ApaG domain
BSY240_2339	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSY240_2340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSY240_2341	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSY240_2343	COG0745	RESPONSE REGULATOR receiver
BSY240_2344	COG0704	Plays a role in the regulation of phosphate uptake
BSY240_2345	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSY240_2346	COG0581	inorganic phosphate transmembrane transporter activity
BSY240_2347	COG0573	inorganic phosphate transmembrane transporter activity
BSY240_2349	COG5002	protein histidine kinase activity
BSY240_235	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSY240_2350	COG2326	polyphosphate kinase activity
BSY240_2356	COG0318	PFAM AMP-dependent synthetase and ligase
BSY240_2357	COG0166	Belongs to the GPI family
BSY240_236	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSY240_2360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSY240_2362	COG0418	dihydroorotase activity
BSY240_2367	COG0529	Catalyzes the synthesis of activated sulfate
BSY240_237	COG1335	isochorismatase
BSY240_2373	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY240_2374	COG3938	Belongs to the proline racemase family
BSY240_2376	COG5002	protein histidine kinase activity
BSY240_2377	COG0594	ribonuclease P activity
BSY240_2378	COG0706	membrane insertase activity
BSY240_238	COG4993	Dehydrogenase
BSY240_2380	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSY240_2381	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY240_2384	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSY240_2385	COG0477	Major facilitator Superfamily
BSY240_2390	COG2171	N-acyltransferase activity
BSY240_2392	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY240_2394	COG0101	tRNA pseudouridine synthase activity
BSY240_2395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSY240_2396	COG0242	peptide deformylase activity
BSY240_2398	COG0840	transmembrane signaling receptor activity
BSY240_240	COG1435	thymidine kinase activity
BSY240_2400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY240_2401	COG0840	transmembrane signaling receptor activity
BSY240_2403	COG0071	Belongs to the small heat shock protein (HSP20) family
BSY240_2405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSY240_2406	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSY240_2407	COG1396	sequence-specific DNA binding
BSY240_2408	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSY240_2410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSY240_2411	COG1702	phosphate starvation-inducible protein PhoH
BSY240_2412	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY240_2417	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSY240_2419	COG0180	Tryptophanyl-tRNA synthetase
BSY240_2420	COG0346	lactoylglutathione lyase activity
BSY240_2423	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSY240_2424	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSY240_2425	COG0583	DNA-binding transcription factor activity
BSY240_2426	COG0281	malic enzyme
BSY240_2426	COG0280	phosphate acetyltransferase
BSY240_2428	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSY240_2429	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY240_2430	COG0116	Belongs to the methyltransferase superfamily
BSY240_2430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSY240_2432	COG0776	regulation of translation
BSY240_2434	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BSY240_2435	COG1137	ATPase activity
BSY240_2437	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSY240_2438	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSY240_2439	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSY240_244	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY240_2440	COG1420	regulation of RNA biosynthetic process
BSY240_2441	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSY240_2443	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSY240_2444	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY240_2445	COG2226	methyltransferase
BSY240_2446	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSY240_2447	COG0268	Binds directly to 16S ribosomal RNA
BSY240_2448	COG1024	Enoyl-CoA hydratase
BSY240_2449	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSY240_245	COG0277	FAD linked oxidase domain protein
BSY240_2450	COG2226	methyltransferase
BSY240_2451	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY240_2452	COG0784	Response regulator, receiver
BSY240_2452	COG2198	Histidine kinase
BSY240_2452	COG5002	protein histidine kinase activity
BSY240_2453	COG3437	response regulator, receiver
BSY240_2454	COG3920	Histidine kinase
BSY240_2455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSY240_2458	COG1741	Belongs to the pirin family
BSY240_2459	COG0351	phosphomethylpyrimidine kinase
BSY240_2460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY240_2461	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSY240_2462	COG0756	dUTP diphosphatase activity
BSY240_2464	COG1522	sequence-specific DNA binding
BSY240_2467	COG1280	lysine exporter protein (LysE YggA)
BSY240_2468	COG1280	lysine exporter protein (LysE YggA)
BSY240_2470	COG3920	Histidine kinase
BSY240_2472	COG0189	ligase activity
BSY240_2473	COG3842	ATPase activity
BSY240_2474	COG0395	ABC-type sugar transport system, permease component
BSY240_2475	COG1175	transmembrane transport
BSY240_2477	COG0792	nuclease activity
BSY240_2478	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSY240_2479	COG0592	DNA-directed DNA polymerase activity
BSY240_2480	COG3963	phosphatidate phosphatase activity
BSY240_2481	COG0284	orotidine-5'-phosphate decarboxylase activity
BSY240_2485	COG1968	undecaprenyl-diphosphatase activity
BSY240_2487	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSY240_2489	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSY240_2498	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSY240_2498	COG0519	Catalyzes the synthesis of GMP from XMP
BSY240_250	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSY240_2500	COG0300	oxidoreductase activity
BSY240_2502	COG1393	Belongs to the ArsC family
BSY240_2503	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSY240_2504	COG2309	aminopeptidase activity
BSY240_2509	COG1278	Cold shock
BSY240_2510	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSY240_2511	COG1570	exodeoxyribonuclease VII activity
BSY240_2514	COG2226	methyltransferase
BSY240_2514	COG0596	Alpha beta hydrolase
BSY240_2514	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY240_2515	COG2076	Multidrug Resistance protein
BSY240_2519	COG4977	sequence-specific DNA binding
BSY240_252	COG0330	HflC and HflK could
BSY240_2520	COG0667	Aldo Keto reductase
BSY240_2521	COG0667	Aldo Keto reductase
BSY240_2522	COG0697	spore germination
BSY240_2524	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_2525	COG1120	ATPase activity
BSY240_2528	COG1162	GTPase activity
BSY240_253	COG0330	HflC and HflK could
BSY240_2530	COG0072	phenylalanine-tRNA ligase activity
BSY240_2530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY240_2534	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSY240_2535	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSY240_2536	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSY240_2537	COG2205	protein histidine kinase activity
BSY240_2538	COG0745	RESPONSE REGULATOR receiver
BSY240_2541	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSY240_2544	COG2271	Major facilitator Superfamily
BSY240_2549	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY240_2556	COG0156	8-amino-7-oxononanoate synthase activity
BSY240_2557	COG1063	alcohol dehydrogenase
BSY240_2558	COG4529	Protein conserved in bacteria
BSY240_256	COG3300	MHYT domain
BSY240_256	COG5001	Diguanylate cyclase
BSY240_2563	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY240_2564	COG0481	GTPase activity
BSY240_2566	COG1733	regulation of RNA biosynthetic process
BSY240_2569	COG3422	double-strand break repair
BSY240_258	COG0560	Phosphoserine phosphatase
BSY240_258	COG3830	Belongs to the UPF0237 family
BSY240_2582	COG0791	NLP P60 protein
BSY240_2584	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY240_2589	COG3685	Protein conserved in bacteria
BSY240_259	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSY240_2592	COG2918	glutathione biosynthetic process
BSY240_2592	COG0189	ligase activity
BSY240_2593	COG0367	asparagine synthase
BSY240_2598	COG1363	Peptidase, m42
BSY240_2599	COG2186	Transcriptional regulator
BSY240_26	COG3842	ATPase activity
BSY240_2601	COG0765	amino acid transport
BSY240_2602	COG1126	abc transporter atp-binding protein
BSY240_2605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_2606	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY240_2608	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_261	COG0028	Belongs to the TPP enzyme family
BSY240_2611	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSY240_2612	COG1309	transcriptional regulator
BSY240_2613	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY240_2613	COG0574	Belongs to the PEP-utilizing enzyme family
BSY240_2616	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY240_262	COG0440	acetolactate synthase activity
BSY240_2623	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BSY240_2624	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BSY240_2626	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSY240_2627	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSY240_2628	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BSY240_263	COG0640	Transcriptional regulator
BSY240_2635	COG4964	Belongs to the GSP D family
BSY240_264	COG0656	L-ascorbic acid biosynthetic process
BSY240_2643	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BSY240_2646	COG4172	Belongs to the ABC transporter superfamily
BSY240_2649	COG4239	(ABC) transporter, permease
BSY240_2650	COG4174	ABC transporter (Permease)
BSY240_2651	COG4166	transmembrane transport
BSY240_2652	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BSY240_2653	COG1803	Methylglyoxal synthase
BSY240_2654	COG0837	glucose binding
BSY240_2655	COG1132	(ABC) transporter
BSY240_2656	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSY240_2657	COG0588	phosphoglycerate mutase activity
BSY240_2659	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY240_2659	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY240_2662	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSY240_2663	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSY240_2664	COG0443	Heat shock 70 kDa protein
BSY240_2666	COG0484	heat shock protein binding
BSY240_2668	COG2900	Belongs to the SlyX family
BSY240_2671	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSY240_2675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY240_2678	COG3474	cytochrome
BSY240_2679	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSY240_2680	COG1605	Chorismate mutase
BSY240_2680	COG0077	Prephenate dehydratase
BSY240_2681	COG2816	NAD+ diphosphatase activity
BSY240_2683	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSY240_2684	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSY240_2686	COG2258	MOSC domain
BSY240_2687	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSY240_2689	COG2814	Major facilitator Superfamily
BSY240_269	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY240_2690	COG0779	Required for maturation of 30S ribosomal subunits
BSY240_2691	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY240_2691	COG0195	Participates in both transcription termination and antitermination
BSY240_2693	COG3064	Membrane
BSY240_2693	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSY240_2694	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSY240_2695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSY240_2696	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSY240_2697	COG1185	polyribonucleotide nucleotidyltransferase activity
BSY240_27	COG3842	ATPase activity
BSY240_2700	COG2197	response regulator
BSY240_2702	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY240_2704	COG2860	membrane
BSY240_2711	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSY240_2712	COG0539	negative regulation of cytoplasmic translation
BSY240_2717	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY240_2718	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSY240_2719	COG4221	oxidoreductase activity
BSY240_2720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSY240_2723	COG1595	DNA-templated transcription, initiation
BSY240_2724	COG3806	Anti-sigma factor
BSY240_2727	COG1793	dna ligase
BSY240_273	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSY240_2731	COG0395	ABC-type sugar transport system, permease component
BSY240_2733	COG3842	ATPase activity
BSY240_2734	COG3842	ATPase activity
BSY240_2737	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_2739	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSY240_274	COG1794	racemase activity, acting on amino acids and derivatives
BSY240_2740	COG1252	NADH dehydrogenase
BSY240_2742	COG3546	catalase activity
BSY240_2746	COG2390	Transcriptional regulator
BSY240_2748	COG1175	transmembrane transport
BSY240_2749	COG0395	ABC-type sugar transport system, permease component
BSY240_2753	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY240_2754	COG1069	ribulokinase activity
BSY240_2755	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_2756	COG2986	histidine ammonia-lyase
BSY240_2757	COG1228	amidohydrolase
BSY240_2758	COG2986	histidine ammonia-lyase
BSY240_276	COG1522	sequence-specific DNA binding
BSY240_2760	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSY240_2764	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY240_2768	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSY240_2769	COG1845	cytochrome c oxidase, subunit III
BSY240_2770	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY240_2771	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSY240_2772	COG0477	Major facilitator Superfamily
BSY240_2776	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_2778	COG3842	ATPase activity
BSY240_2779	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY240_2781	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_2782	COG4172	Belongs to the ABC transporter superfamily
BSY240_2784	COG0601	transmembrane transport
BSY240_2785	COG0747	negative chemotaxis
BSY240_2788	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSY240_2789	COG1454	alcohol dehydrogenase
BSY240_2790	COG2186	Transcriptional regulator
BSY240_2792	COG2186	Transcriptional regulator
BSY240_2793	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_2795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY240_2796	COG1063	alcohol dehydrogenase
BSY240_2797	COG1312	Catalyzes the dehydration of D-mannonate
BSY240_2798	COG0246	Mannitol dehydrogenase
BSY240_2799	COG0235	Class ii aldolase
BSY240_2800	COG3395	kinase activity
BSY240_2801	COG1609	Transcriptional regulator
BSY240_2803	COG1129	ABC transporter
BSY240_2804	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_2805	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_2806	COG2084	Dehydrogenase
BSY240_2807	COG3622	Belongs to the hyi family
BSY240_2815	COG2423	ornithine cyclodeaminase activity
BSY240_2816	COG1643	Atp-dependent helicase
BSY240_2818	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSY240_2820	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_2821	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSY240_2823	COG2124	cytochrome p450
BSY240_2825	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSY240_2826	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSY240_2827	COG0131	Imidazoleglycerol-phosphate dehydratase
BSY240_2828	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSY240_2829	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSY240_283	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSY240_2830	COG0107	imidazoleglycerol-phosphate synthase activity
BSY240_2831	COG0140	phosphoribosyl-ATP diphosphatase activity
BSY240_2832	COG1072	(Pantothenic acid kinase))
BSY240_2833	COG3145	DNA-N1-methyladenine dioxygenase activity
BSY240_2835	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BSY240_2836	COG0745	RESPONSE REGULATOR receiver
BSY240_2837	COG0642	Histidine kinase
BSY240_2839	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSY240_2839	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BSY240_284	COG3706	GGDEF domain
BSY240_284	COG2203	Gaf domain
BSY240_284	COG4251	negative regulation of phosphorylation
BSY240_284	COG5001	Diguanylate cyclase
BSY240_2840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSY240_2841	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSY240_2842	COG2205	protein histidine kinase activity
BSY240_2843	COG3178	'Phosphotransferase
BSY240_2844	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSY240_2849	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSY240_285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY240_2850	COG0159	tryptophan synthase activity
BSY240_2851	COG0133	tryptophan synthase activity
BSY240_2852	COG0135	phosphoribosylanthranilate isomerase activity
BSY240_2857	COG0187	DNA topoisomerase II activity
BSY240_2863	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BSY240_2864	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSY240_2865	COG0237	dephospho-CoA kinase activity
BSY240_2866	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSY240_2867	COG0424	maF-like protein
BSY240_2868	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSY240_2869	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSY240_2871	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSY240_2872	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSY240_2873	COG0445	tRNA wobble uridine modification
BSY240_2874	COG0357	Ribosomal RNA small subunit methyltransferase G
BSY240_2875	COG1192	Involved in chromosome partitioning
BSY240_2877	COG1475	DNA binding
BSY240_2879	COG0495	leucyl-tRNA aminoacylation
BSY240_288	COG0384	phenazine biosynthesis protein PhzF
BSY240_2880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSY240_2883	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY240_2886	COG0501	Belongs to the peptidase M48B family
BSY240_2889	COG0138	bifunctional purine biosynthesis protein purh
BSY240_2890	COG2270	Major facilitator Superfamily
BSY240_2893	COG0288	reversible hydration of carbon dioxide
BSY240_2895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSY240_2899	COG4213	ABC transporter substrate-binding protein
BSY240_29	COG0395	ABC-type sugar transport system, permease component
BSY240_290	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSY240_2901	COG4214	carbohydrate transport
BSY240_2906	COG3734	2-keto-3-deoxy-galactonokinase
BSY240_2907	COG0800	Aldolase
BSY240_2909	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSY240_291	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY240_2910	COG4133	protoheme IX ABC transporter activity
BSY240_2911	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY240_2912	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY240_2916	COG2917	probably involved in intracellular septation
BSY240_2917	COG0552	protein localization to endoplasmic reticulum
BSY240_2918	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY240_2919	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSY240_292	COG4558	Periplasmic binding protein
BSY240_2921	COG2022	thiamine diphosphate biosynthetic process
BSY240_2924	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSY240_2926	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSY240_2927	COG0287	Prephenate dehydrogenase
BSY240_2927	COG1605	Chorismate mutase
BSY240_2928	COG0228	four-way junction DNA binding
BSY240_2929	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSY240_2931	COG0336	Belongs to the RNA methyltransferase TrmD family
BSY240_2932	COG0335	large ribosomal subunit rRNA binding
BSY240_2934	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSY240_2937	COG0765	amino acid transport
BSY240_2938	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_2942	COG0745	RESPONSE REGULATOR receiver
BSY240_2945	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSY240_2946	COG1674	ftsk spoiiie
BSY240_2947	COG0004	ammonium transporteR
BSY240_2948	COG0347	Belongs to the P(II) protein family
BSY240_2949	COG1946	Acyl-CoA thioesterase
BSY240_295	COG3264	Mechanosensitive ion channel
BSY240_295	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BSY240_2950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY240_2951	COG2835	tetraacyldisaccharide 4'-kinase activity
BSY240_2958	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BSY240_2962	COG0066	3-isopropylmalate dehydratase activity
BSY240_2963	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BSY240_2964	COG0473	3-isopropylmalate dehydrogenase activity
BSY240_2965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY240_2968	COG4783	chaperone-mediated protein folding
BSY240_2969	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BSY240_298	COG0745	RESPONSE REGULATOR receiver
BSY240_298	COG3706	GGDEF domain
BSY240_2980	COG0587	DNA-directed DNA polymerase activity
BSY240_2981	COG0587	DNA-directed DNA polymerase activity
BSY240_2982	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY240_2987	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSY240_2988	COG0494	nUDIX hydrolase
BSY240_299	COG1131	(ABC) transporter
BSY240_2990	COG0793	Belongs to the peptidase S41A family
BSY240_2992	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSY240_2993	COG0799	negative regulation of ribosome biogenesis
BSY240_2994	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSY240_2995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSY240_2996	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSY240_2997	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSY240_300	COG0842	Transport permease protein
BSY240_3000	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSY240_3001	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSY240_3002	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY240_3005	COG3454	Phosphonate metabolism
BSY240_3006	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BSY240_3007	COG3639	organic phosphonate transmembrane transporter activity
BSY240_3008	COG3639	organic phosphonate transmembrane transporter activity
BSY240_3010	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSY240_3012	COG4778	phosphonate C-P lyase system protein PhnL
BSY240_3013	COG4107	phosphonate C-P lyase system protein PhnK
BSY240_3014	COG3627	carbon phosphorus lyase activity
BSY240_3015	COG3626	phosphonate metabolism
BSY240_3016	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BSY240_3017	COG3624	Phosphonate C-P lyase system protein PhnG
BSY240_3018	COG2188	Transcriptional regulator
BSY240_3022	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSY240_3022	COG0519	Catalyzes the synthesis of GMP from XMP
BSY240_3024	COG0346	lactoylglutathione lyase activity
BSY240_3025	COG0400	carboxylic ester hydrolase activity
BSY240_3026	COG1063	alcohol dehydrogenase
BSY240_3027	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_3028	COG1129	ABC transporter
BSY240_3029	COG1879	ABC-type sugar transport system periplasmic component
BSY240_303	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BSY240_3032	COG2721	sulfolactate sulfo-lyase activity
BSY240_3033	COG1802	Transcriptional regulator
BSY240_3034	COG0246	Mannitol dehydrogenase
BSY240_3037	COG1175	transmembrane transport
BSY240_3038	COG0395	ABC-type sugar transport system, permease component
BSY240_304	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSY240_3042	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3045	COG3046	protein related to deoxyribodipyrimidine photolyase
BSY240_3048	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BSY240_3049	COG3459	Glycosyltransferase 36 associated
BSY240_305	COG2202	Pas domain
BSY240_305	COG2205	protein histidine kinase activity
BSY240_3050	COG1309	transcriptional regulator
BSY240_3051	COG0697	spore germination
BSY240_3052	COG1473	amidohydrolase
BSY240_3053	COG2223	nitrite transmembrane transporter activity
BSY240_3054	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSY240_3055	COG2885	chlorophyll binding
BSY240_3057	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY240_3058	COG0142	geranyltranstransferase activity
BSY240_3059	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSY240_3061	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSY240_3063	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BSY240_3065	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3072	COG1329	Transcriptional regulator
BSY240_3073	COG0670	Belongs to the BI1 family
BSY240_3075	COG4181	ATPase activity
BSY240_3077	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSY240_3078	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BSY240_3079	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSY240_308	COG1573	uracil-dna glycosylase
BSY240_3082	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSY240_3083	COG1280	lysine exporter protein (LysE YggA)
BSY240_3084	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3085	COG3609	addiction module antidote protein, CC2985 family
BSY240_3086	COG3668	Plasmid stabilization system
BSY240_3087	COG0137	argininosuccinate synthase activity
BSY240_3088	COG2814	Major facilitator Superfamily
BSY240_309	COG1522	sequence-specific DNA binding
BSY240_3090	COG0339	signal peptide processing
BSY240_3094	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSY240_3095	COG1872	DUF167
BSY240_3103	COG0181	hydroxymethylbilane synthase activity
BSY240_3104	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSY240_3105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSY240_3109	COG2264	protein methyltransferase activity
BSY240_311	COG2084	Dehydrogenase
BSY240_3115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSY240_3116	COG0039	L-malate dehydrogenase activity
BSY240_3117	COG0045	succinate-CoA ligase (ADP-forming) activity
BSY240_3118	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSY240_3120	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY240_3123	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3128	COG4974	Belongs to the 'phage' integrase family
BSY240_3132	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSY240_3133	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSY240_3134	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSY240_3135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSY240_3136	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSY240_3138	COG4948	Mandelate Racemase Muconate Lactonizing
BSY240_3139	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_3141	COG0039	L-malate dehydrogenase activity
BSY240_3146	COG3383	formate dehydrogenase (NAD+) activity
BSY240_3147	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSY240_3149	COG0252	asparaginase activity
BSY240_315	COG5425	PFAM Usg family protein
BSY240_3150	COG0835	chemotaxis
BSY240_3155	COG0729	surface antigen
BSY240_3160	COG0156	8-amino-7-oxononanoate synthase activity
BSY240_3162	COG3813	Protein conserved in bacteria
BSY240_3163	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSY240_3166	COG3685	Protein conserved in bacteria
BSY240_3174	COG1473	amidohydrolase
BSY240_3175	COG1686	Belongs to the peptidase S11 family
BSY240_3176	COG0425	Belongs to the sulfur carrier protein TusA family
BSY240_3176	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BSY240_3177	COG0523	cobalamin synthesis protein
BSY240_3178	COG3034	peptidoglycan biosynthetic process
BSY240_3179	COG0825	malonyl-CoA metabolic process
BSY240_3180	COG4974	Belongs to the 'phage' integrase family
BSY240_3182	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSY240_3183	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSY240_3184	COG4536	flavin adenine dinucleotide binding
BSY240_319	COG2885	chlorophyll binding
BSY240_3190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BSY240_3191	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSY240_3196	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY240_3197	COG2226	methyltransferase
BSY240_3198	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY240_3199	COG0287	Prephenate dehydrogenase
BSY240_320	COG1763	Mo-molybdopterin cofactor biosynthetic process
BSY240_3201	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BSY240_3205	COG2884	Cell division ATP-binding protein ftsE
BSY240_321	COG0746	molybdenum cofactor guanylyltransferase activity
BSY240_3212	COG0165	Argininosuccinate lyase
BSY240_3213	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSY240_3214	COG2200	EAL domain
BSY240_3215	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY240_3216	COG4208	sulfate ABC transporter
BSY240_3218	COG4150	thiosulfate binding
BSY240_3219	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY240_3221	COG2086	electron transfer activity
BSY240_3225	COG0300	oxidoreductase activity
BSY240_3226	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY240_3234	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY240_3238	COG0653	protein targeting
BSY240_3239	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY240_3240	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSY240_3242	COG0494	nUDIX hydrolase
BSY240_3245	COG2226	methyltransferase
BSY240_3247	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSY240_3248	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY240_325	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSY240_3251	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSY240_3253	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BSY240_3253	COG0392	lysyltransferase activity
BSY240_3254	COG0527	aspartate kinase activity
BSY240_3256	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSY240_3257	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY240_3259	COG0542	response to heat
BSY240_326	COG1846	Transcriptional regulator
BSY240_3260	COG0741	lytic transglycosylase activity
BSY240_3260	COG0739	heme binding
BSY240_3260	COG1196	nuclear chromosome segregation
BSY240_3269	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY240_3271	COG0444	Belongs to the ABC transporter superfamily
BSY240_3272	COG4608	Belongs to the ABC transporter superfamily
BSY240_3274	COG1522	sequence-specific DNA binding
BSY240_3276	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_3282	COG3964	amidohydrolase
BSY240_3286	COG1921	L-seryl-tRNASec selenium transferase activity
BSY240_3289	COG1940	carbohydrate kinase activity
BSY240_3290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY240_3297	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY240_3299	COG0747	negative chemotaxis
BSY240_330	COG3706	GGDEF domain
BSY240_3301	COG4172	Belongs to the ABC transporter superfamily
BSY240_3302	COG0784	Response regulator, receiver
BSY240_3302	COG4191	Histidine kinase
BSY240_3304	COG3685	Protein conserved in bacteria
BSY240_3305	COG0753	catalase activity
BSY240_3306	COG0784	Response regulator, receiver
BSY240_3306	COG4191	Histidine kinase
BSY240_3307	COG3920	Histidine kinase
BSY240_331	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BSY240_331	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BSY240_3312	COG5001	Diguanylate cyclase
BSY240_3312	COG3300	MHYT domain
BSY240_3313	COG4604	ABC transporter, ATP-binding protein
BSY240_3315	COG4771	TonB-dependent receptor
BSY240_3316	COG4178	(ABC) transporter
BSY240_3321	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BSY240_3324	COG2197	response regulator
BSY240_3325	COG1120	ATPase activity
BSY240_3328	COG2080	2 iron, 2 sulfur cluster binding
BSY240_3329	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSY240_333	COG0114	fumarate hydratase activity
BSY240_3330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY240_3332	COG0747	negative chemotaxis
BSY240_3333	COG0601	transmembrane transport
BSY240_3335	COG4608	Belongs to the ABC transporter superfamily
BSY240_3337	COG0471	metal ion transport
BSY240_3337	COG3273	potassium ion transport
BSY240_3338	COG1115	amino acid carrier protein
BSY240_3340	COG0673	inositol 2-dehydrogenase activity
BSY240_3343	COG1609	Transcriptional regulator
BSY240_3346	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BSY240_335	COG0546	phosphoglycolate phosphatase activity
BSY240_3355	COG0251	oxidation-reduction process
BSY240_3356	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSY240_3358	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_3359	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY240_336	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSY240_3360	COG1116	anion transmembrane transporter activity
BSY240_3362	COG0583	DNA-binding transcription factor activity
BSY240_3366	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSY240_3367	COG0517	IMP dehydrogenase activity
BSY240_3369	COG2176	DNA-directed DNA polymerase activity
BSY240_3369	COG5002	protein histidine kinase activity
BSY240_3376	COG0129	dihydroxy-acid dehydratase activity
BSY240_3377	COG2084	Dehydrogenase
BSY240_3378	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY240_3379	COG0277	FAD linked oxidase domain protein
BSY240_3380	COG1802	Transcriptional regulator
BSY240_3382	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY240_3383	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY240_3384	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_3385	COG0697	spore germination
BSY240_3387	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSY240_3388	COG3254	rhamnose metabolic process
BSY240_3389	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_3390	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_3391	COG1129	ABC transporter
BSY240_3394	COG3347	Dehydrogenase
BSY240_3394	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3396	COG4952	isomerase
BSY240_3397	COG0670	Belongs to the BI1 family
BSY240_34	COG3639	organic phosphonate transmembrane transporter activity
BSY240_3400	COG3932	Exopolysaccharide synthesis, ExoD
BSY240_3408	COG4953	penicillin-binding protein 1C
BSY240_3409	COG2373	Large extracellular alpha-helical protein
BSY240_341	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSY240_3410	COG0583	DNA-binding transcription factor activity
BSY240_3411	COG1960	acyl-CoA dehydrogenase activity
BSY240_3415	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3416	COG1285	pathogenesis
BSY240_3419	COG0307	riboflavin synthase, alpha
BSY240_3422	COG0848	biopolymer transport protein
BSY240_3425	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_3426	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_3429	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSY240_3431	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BSY240_3438	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY240_3438	COG0546	phosphoglycolate phosphatase activity
BSY240_344	COG1368	sulfuric ester hydrolase activity
BSY240_3445	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BSY240_3446	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSY240_3448	COG0583	DNA-binding transcription factor activity
BSY240_3450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BSY240_3453	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY240_3455	COG1309	transcriptional regulator
BSY240_3456	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSY240_3465	COG0534	Mate efflux family protein
BSY240_3466	COG0697	spore germination
BSY240_347	COG0823	Involved in the tonB-independent uptake of proteins
BSY240_3470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY240_3471	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY240_3472	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY240_3473	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY240_3475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_3476	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_3479	COG1126	abc transporter atp-binding protein
BSY240_3480	COG3257	ureidoglycine aminohydrolase activity
BSY240_3486	COG1215	transferase activity, transferring glycosyl groups
BSY240_3489	COG1309	transcriptional regulator
BSY240_349	COG0778	Nitroreductase
BSY240_3494	COG2207	Transcriptional regulator
BSY240_3499	COG0730	response to heat
BSY240_35	COG3639	organic phosphonate transmembrane transporter activity
BSY240_3500	COG3453	Protein conserved in bacteria
BSY240_3500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY240_3502	COG0642	Histidine kinase
BSY240_3503	COG0745	RESPONSE REGULATOR receiver
BSY240_3505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSY240_3506	COG1388	LysM domain
BSY240_3506	COG1376	ErfK ybiS ycfS ynhG family protein
BSY240_3507	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSY240_3507	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSY240_3511	COG0785	Cytochrome C biogenesis protein
BSY240_3516	COG3258	Cytochrome c
BSY240_3517	COG0737	Belongs to the 5'-nucleotidase family
BSY240_3518	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY240_352	COG0281	malic enzyme
BSY240_352	COG0280	phosphate acetyltransferase
BSY240_3521	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY240_3522	COG2391	methyltransferase activity
BSY240_3525	COG0745	RESPONSE REGULATOR receiver
BSY240_3527	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BSY240_3528	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_3530	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_3531	COG0747	negative chemotaxis
BSY240_3532	COG4608	Belongs to the ABC transporter superfamily
BSY240_3533	COG0444	Belongs to the ABC transporter superfamily
BSY240_3534	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY240_3535	COG0601	transmembrane transport
BSY240_3538	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY240_354	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSY240_3540	COG1802	Transcriptional regulator
BSY240_3541	COG1032	radical SAM domain protein
BSY240_3546	COG2274	protein secretion by the type I secretion system
BSY240_3548	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY240_355	COG1127	ABC transporter
BSY240_3554	COG1178	ABC-type Fe3 transport system permease component
BSY240_3558	COG2030	dehydratase
BSY240_3560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY240_3561	COG1960	acyl-CoA dehydrogenase activity
BSY240_3566	COG2169	Transcriptional regulator
BSY240_3568	COG0183	Belongs to the thiolase family
BSY240_3569	COG1960	acyl-CoA dehydrogenase activity
BSY240_3571	COG1124	(ABC) transporter
BSY240_3572	COG0444	Belongs to the ABC transporter superfamily
BSY240_3574	COG0601	transmembrane transport
BSY240_3577	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY240_3580	COG1414	Transcriptional regulator
BSY240_3581	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BSY240_3582	COG3485	protocatechuate 3,4-dioxygenase
BSY240_3584	COG4177	L-phenylalanine transmembrane transporter activity
BSY240_3590	COG3485	protocatechuate 3,4-dioxygenase
BSY240_3591	COG0583	DNA-binding transcription factor activity
BSY240_3595	COG0583	DNA-binding transcription factor activity
BSY240_3596	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY240_3597	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSY240_360	COG0633	Ferredoxin
BSY240_3600	COG4134	Bacterial extracellular solute-binding protein
BSY240_3601	COG4135	transport system, permease component
BSY240_3602	COG4136	ATPase activity
BSY240_3605	COG0395	ABC-type sugar transport system, permease component
BSY240_3607	COG3842	ATPase activity
BSY240_3608	COG3534	alpha-L-arabinofuranosidase
BSY240_3613	COG1609	Transcriptional regulator
BSY240_3614	COG0673	inositol 2-dehydrogenase activity
BSY240_362	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BSY240_3621	COG0069	glutamate synthase activity
BSY240_3622	COG2218	PFAM glutamate synthase alpha subunit domain protein
BSY240_3623	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSY240_3625	COG2855	membrane
BSY240_3626	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_3630	COG4989	oxidoreductase activity
BSY240_3636	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSY240_3639	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BSY240_364	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSY240_3640	COG0644	oxidoreductase
BSY240_3641	COG2211	Major facilitator Superfamily
BSY240_3642	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY240_3646	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY240_3647	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY240_3648	COG1429	ligase activity, forming nitrogen-metal bonds
BSY240_3649	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BSY240_3656	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BSY240_3658	COG0156	8-amino-7-oxononanoate synthase activity
BSY240_3659	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BSY240_366	COG3768	UPF0283 membrane protein
BSY240_3666	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY240_3667	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY240_3668	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BSY240_3669	COG1063	alcohol dehydrogenase
BSY240_367	COG3106	COG3106 Predicted ATPase
BSY240_3670	COG0500	methyltransferase
BSY240_3671	COG0142	geranyltranstransferase activity
BSY240_3675	COG1562	ergosterol biosynthetic process
BSY240_3676	COG1233	COG1233 Phytoene dehydrogenase and related
BSY240_3678	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BSY240_3681	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY240_3683	COG0640	Transcriptional regulator
BSY240_3686	COG0835	chemotaxis
BSY240_3688	COG1879	ABC-type sugar transport system periplasmic component
BSY240_3689	COG1129	ABC transporter
BSY240_369	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BSY240_3690	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_3691	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_3692	COG2186	Transcriptional regulator
BSY240_3694	COG3842	ATPase activity
BSY240_3696	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_3697	COG0395	ABC-type sugar transport system, permease component
BSY240_37	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSY240_3701	COG1940	carbohydrate kinase activity
BSY240_3702	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BSY240_3703	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY240_3705	COG0673	inositol 2-dehydrogenase activity
BSY240_3706	COG1175	transmembrane transport
BSY240_3707	COG0395	ABC-type sugar transport system, permease component
BSY240_3709	COG3842	ATPase activity
BSY240_3715	COG1737	Transcriptional regulator
BSY240_3716	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_372	COG2313	pseudouridylate synthase activity
BSY240_3720	COG3142	Participates in the control of copper homeostasis
BSY240_3721	COG5001	Diguanylate cyclase
BSY240_3721	COG3300	MHYT domain
BSY240_3724	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSY240_3726	COG1414	Transcriptional regulator
BSY240_3727	COG0583	DNA-binding transcription factor activity
BSY240_3728	COG2267	carboxylic ester hydrolase activity
BSY240_3729	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSY240_3730	COG3485	protocatechuate 3,4-dioxygenase
BSY240_3731	COG3485	protocatechuate 3,4-dioxygenase
BSY240_3734	COG1595	DNA-templated transcription, initiation
BSY240_3738	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY240_3739	COG3002	Belongs to the UPF0753 family
BSY240_374	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSY240_3740	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BSY240_3743	COG3842	ATPase activity
BSY240_3744	COG0395	ABC-type sugar transport system, permease component
BSY240_3745	COG1175	transmembrane transport
BSY240_3746	COG1486	melibiose metabolic process
BSY240_3748	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BSY240_3749	COG0840	transmembrane signaling receptor activity
BSY240_3749	COG2972	Histidine kinase
BSY240_375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY240_3756	COG0745	RESPONSE REGULATOR receiver
BSY240_3758	COG2200	EAL domain
BSY240_376	COG3706	GGDEF domain
BSY240_3762	COG1609	Transcriptional regulator
BSY240_3765	COG0673	inositol 2-dehydrogenase activity
BSY240_3768	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY240_3769	COG3962	Belongs to the TPP enzyme family
BSY240_377	COG0659	secondary active sulfate transmembrane transporter activity
BSY240_3772	COG3718	enzyme involved in inositol metabolism
BSY240_3776	COG0583	DNA-binding transcription factor activity
BSY240_3780	COG1487	ribonuclease activity
BSY240_3781	COG3842	ATPase activity
BSY240_3782	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_3789	COG0625	glutathione transferase activity
BSY240_379	COG0538	isocitrate dehydrogenase activity
BSY240_3790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY240_3791	COG1396	sequence-specific DNA binding
BSY240_3791	COG3800	Transcriptional regulator
BSY240_3794	COG1024	Enoyl-CoA hydratase
BSY240_3795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSY240_3800	COG3237	CsbD-like
BSY240_3803	COG0784	Response regulator, receiver
BSY240_3812	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY240_3815	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BSY240_3818	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_382	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BSY240_3823	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_3826	COG1177	transmembrane transport
BSY240_3827	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_3828	COG3842	ATPase activity
BSY240_3829	COG0154	amidase activity
BSY240_383	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSY240_3831	COG3454	Phosphonate metabolism
BSY240_3832	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BSY240_3834	COG3191	aminopeptidase activity
BSY240_3835	COG0671	phosphoesterase, PA-phosphatase related
BSY240_3836	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY240_3837	COG0601	transmembrane transport
BSY240_3839	COG1473	amidohydrolase
BSY240_384	COG1253	flavin adenine dinucleotide binding
BSY240_3840	COG4172	Belongs to the ABC transporter superfamily
BSY240_3842	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY240_3846	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSY240_3850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSY240_3855	COG1177	transmembrane transport
BSY240_3856	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_3857	COG3842	ATPase activity
BSY240_3858	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BSY240_3859	COG0583	DNA-binding transcription factor activity
BSY240_3860	COG0697	spore germination
BSY240_3862	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSY240_3863	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSY240_3864	COG1121	(ABC) transporter
BSY240_3870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSY240_3871	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY240_3872	COG3273	potassium ion transport
BSY240_3872	COG0471	metal ion transport
BSY240_3873	COG1253	flavin adenine dinucleotide binding
BSY240_3874	COG1309	transcriptional regulator
BSY240_3877	COG1609	Transcriptional regulator
BSY240_3878	COG1070	Carbohydrate kinase
BSY240_3879	COG2115	Belongs to the xylose isomerase family
BSY240_388	COG2195	Cleaves the N-terminal amino acid of tripeptides
BSY240_3880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY240_3882	COG1609	Transcriptional regulator
BSY240_3883	COG1129	ABC transporter
BSY240_3884	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_3885	COG1879	ABC-type sugar transport system periplasmic component
BSY240_3888	COG0673	inositol 2-dehydrogenase activity
BSY240_389	COG1686	Belongs to the peptidase S11 family
BSY240_3890	COG1733	regulation of RNA biosynthetic process
BSY240_3892	COG5001	Diguanylate cyclase
BSY240_3895	COG0747	negative chemotaxis
BSY240_3896	COG0601	transmembrane transport
BSY240_3897	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY240_3899	COG4172	Belongs to the ABC transporter superfamily
BSY240_39	COG4778	phosphonate C-P lyase system protein PhnL
BSY240_390	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSY240_3901	COG0800	Aldolase
BSY240_3905	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BSY240_3907	COG0583	DNA-binding transcription factor activity
BSY240_391	COG2066	Belongs to the glutaminase family
BSY240_3910	COG3047	cAMP biosynthetic process
BSY240_3912	COG0840	transmembrane signaling receptor activity
BSY240_3915	COG0523	cobalamin synthesis protein
BSY240_3918	COG1846	Transcriptional regulator
BSY240_3919	COG1609	Transcriptional regulator
BSY240_392	COG0037	tRNA processing
BSY240_3920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSY240_3922	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY240_3925	COG5001	Diguanylate cyclase
BSY240_3929	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSY240_393	COG0483	inositol monophosphate 1-phosphatase activity
BSY240_3930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_3932	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY240_3932	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY240_3935	COG2337	Toxic component of a toxin-antitoxin (TA) module
BSY240_3939	COG0431	NADPH-dependent FMN reductase
BSY240_3941	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSY240_3944	COG0033	Phosphoglucomutase
BSY240_3945	COG0297	glycogen (starch) synthase activity
BSY240_3946	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BSY240_3947	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSY240_3948	COG0058	SHG alpha-glucan phosphorylase activity
BSY240_3951	COG2308	Evidence 4 Homologs of previously reported genes of
BSY240_3951	COG2307	Protein conserved in bacteria
BSY240_3953	COG0662	Cupin 2, conserved barrel domain protein
BSY240_3953	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BSY240_3959	COG0483	inositol monophosphate 1-phosphatase activity
BSY240_3961	COG0071	Belongs to the small heat shock protein (HSP20) family
BSY240_3964	COG3220	belongs to the UPF0276 family
BSY240_3967	COG0067	glutamate synthase
BSY240_3967	COG0069	glutamate synthase activity
BSY240_3967	COG0070	glutamate synthase
BSY240_397	COG0483	inositol monophosphate 1-phosphatase activity
BSY240_3971	COG2951	lytic endotransglycosylase activity
BSY240_3972	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSY240_3974	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BSY240_3974	COG0517	IMP dehydrogenase activity
BSY240_3975	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSY240_3977	COG0330	HflC and HflK could
BSY240_3978	COG2972	Histidine kinase
BSY240_3978	COG0840	transmembrane signaling receptor activity
BSY240_398	COG2814	Major facilitator Superfamily
BSY240_3980	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSY240_3981	COG0737	Belongs to the 5'-nucleotidase family
BSY240_3983	COG5310	Homospermidine synthase
BSY240_3989	COG0512	Glutamine amidotransferase of anthranilate synthase
BSY240_3989	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSY240_3991	COG2204	response regulator
BSY240_3993	COG3750	Belongs to the UPF0335 family
BSY240_3997	COG0469	pyruvate kinase activity
BSY240_4	COG0583	DNA-binding transcription factor activity
BSY240_40	COG4107	phosphonate C-P lyase system protein PhnK
BSY240_4001	COG0457	Tetratricopeptide repeat
BSY240_4002	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSY240_4003	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSY240_4004	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSY240_4007	COG0640	Transcriptional regulator
BSY240_4011	COG3174	membrane
BSY240_4012	COG0483	inositol monophosphate 1-phosphatase activity
BSY240_4014	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BSY240_4014	COG2885	chlorophyll binding
BSY240_4016	COG1132	(ABC) transporter
BSY240_4017	COG0254	rRNA binding
BSY240_4024	COG0384	phenazine biosynthesis protein PhzF
BSY240_4025	COG3588	fructose-bisphosphate aldolase
BSY240_4026	COG0126	phosphoglycerate kinase activity
BSY240_4027	COG3263	regulation of cellular component size
BSY240_4028	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BSY240_403	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY240_4033	COG0840	transmembrane signaling receptor activity
BSY240_4033	COG2972	Histidine kinase
BSY240_4034	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSY240_4035	COG1692	metallophosphoesterase
BSY240_4036	COG0840	transmembrane signaling receptor activity
BSY240_4039	COG0217	transcriptional regulatory protein
BSY240_404	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY240_4040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSY240_4041	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY240_4042	COG0037	tRNA processing
BSY240_4044	COG2885	chlorophyll binding
BSY240_4045	COG0823	Involved in the tonB-independent uptake of proteins
BSY240_4049	COG0824	Thioesterase
BSY240_4051	COG2318	DinB family
BSY240_4052	COG0494	nUDIX hydrolase
BSY240_4053	COG2255	four-way junction helicase activity
BSY240_4056	COG0632	four-way junction helicase activity
BSY240_4059	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSY240_4060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY240_4061	COG0840	transmembrane signaling receptor activity
BSY240_4064	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSY240_4065	COG1271	oxidase subunit
BSY240_4066	COG1294	oxidase, subunit
BSY240_407	COG0047	phosphoribosylformylglycinamidine synthase activity
BSY240_4072	COG0673	inositol 2-dehydrogenase activity
BSY240_4076	COG0482	sulfurtransferase activity
BSY240_4077	COG4948	Mandelate Racemase Muconate Lactonizing
BSY240_4080	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BSY240_4081	COG2204	response regulator
BSY240_4082	COG4191	Histidine kinase
BSY240_4083	COG1301	dicarboxylic acid transport
BSY240_4085	COG0346	lactoylglutathione lyase activity
BSY240_4087	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSY240_409	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY240_4091	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSY240_4092	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_4096	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSY240_4097	COG0697	spore germination
BSY240_4098	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSY240_41	COG3627	carbon phosphorus lyase activity
BSY240_410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSY240_4100	COG1131	(ABC) transporter
BSY240_4102	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY240_4103	COG0564	pseudouridine synthase activity
BSY240_4105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY240_4113	COG2388	GCN5-related N-acetyl-transferase
BSY240_412	COG5001	Diguanylate cyclase
BSY240_4120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_4121	COG4311	Sarcosine oxidase, delta subunit
BSY240_4122	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY240_4122	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY240_4124	COG1408	metallophosphoesterase
BSY240_4130	COG0411	ABC transporter
BSY240_4133	COG0683	leucine binding
BSY240_4136	COG2205	protein histidine kinase activity
BSY240_4136	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_4146	COG0829	nickel cation binding
BSY240_4147	COG0831	urea catabolic process
BSY240_4148	COG0832	Belongs to the urease beta subunit family
BSY240_4149	COG3755	Protein conserved in bacteria
BSY240_4150	COG1442	glycosyl transferase family 8
BSY240_4151	COG0804	urea catabolic process
BSY240_4153	COG3706	GGDEF domain
BSY240_4154	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BSY240_4155	COG0830	nickel cation binding
BSY240_4156	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSY240_4157	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY240_4159	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY240_4160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY240_4161	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY240_4162	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY240_417	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSY240_4170	COG1309	transcriptional regulator
BSY240_4171	COG3932	Exopolysaccharide synthesis, ExoD
BSY240_4174	COG0493	'glutamate synthase
BSY240_4179	COG2346	COG2346, Truncated hemoglobins
BSY240_4180	COG0488	(ABC) transporter
BSY240_4187	COG0385	Bile acid
BSY240_4188	COG0318	PFAM AMP-dependent synthetase and ligase
BSY240_4194	COG2308	Evidence 4 Homologs of previously reported genes of
BSY240_4196	COG0513	Belongs to the DEAD box helicase family
BSY240_4198	COG4335	DNA alkylation repair
BSY240_42	COG3626	phosphonate metabolism
BSY240_4201	COG0840	transmembrane signaling receptor activity
BSY240_4202	COG5598	trimethylamine methyltransferase
BSY240_4203	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_4203	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BSY240_4204	COG5002	protein histidine kinase activity
BSY240_4204	COG2205	protein histidine kinase activity
BSY240_4204	COG0784	Response regulator, receiver
BSY240_4205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_4205	COG2022	thiamine diphosphate biosynthetic process
BSY240_4206	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BSY240_421	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_4210	COG1064	alcohol dehydrogenase
BSY240_4211	COG3648	Uricase
BSY240_4211	COG3195	allantoin biosynthetic process
BSY240_4213	COG0174	glutamine synthetase
BSY240_4215	COG0534	Mate efflux family protein
BSY240_4216	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BSY240_4217	COG2351	hydroxyisourate hydrolase activity
BSY240_4219	COG1304	FMN binding
BSY240_4221	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_4223	COG0583	DNA-binding transcription factor activity
BSY240_4226	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY240_4228	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_423	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY240_4230	COG0024	Methionine aminopeptidase
BSY240_4232	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
BSY240_4237	COG1160	GTP binding
BSY240_4238	COG0438	transferase activity, transferring glycosyl groups
BSY240_4238	COG0297	glycogen (starch) synthase activity
BSY240_4239	COG0366	Alpha amylase catalytic
BSY240_424	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSY240_4243	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSY240_4257	COG4175	Glycine betaine
BSY240_4258	COG4176	ABC-type proline glycine betaine transport system permease component
BSY240_4268	COG2197	response regulator
BSY240_427	COG3608	succinylglutamate desuccinylase aspartoacylase
BSY240_427	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSY240_4270	COG0506	proline dehydrogenase activity
BSY240_4270	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSY240_4270	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSY240_4271	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BSY240_4272	COG4771	TonB-dependent receptor
BSY240_4274	COG0512	Glutamine amidotransferase of anthranilate synthase
BSY240_4274	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSY240_4277	COG4774	siderophore transport
BSY240_4278	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSY240_4279	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSY240_428	COG2068	MobA-Related Protein
BSY240_4287	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSY240_4298	COG1522	sequence-specific DNA binding
BSY240_4300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BSY240_4301	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BSY240_4302	COG0740	serine-type endopeptidase activity
BSY240_4306	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BSY240_431	COG0513	Belongs to the DEAD box helicase family
BSY240_4310	COG0019	diaminopimelate decarboxylase activity
BSY240_4311	COG5001	Diguanylate cyclase
BSY240_4311	COG5002	protein histidine kinase activity
BSY240_4311	COG3447	MASE1 domain protein
BSY240_4312	COG3135	benzoate transporter
BSY240_4315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY240_4316	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY240_4316	COG0596	Alpha beta hydrolase
BSY240_4319	COG0435	Glutathione S-transferase
BSY240_432	COG0739	heme binding
BSY240_4322	COG0454	-acetyltransferase
BSY240_4323	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BSY240_4327	COG0714	Associated with various cellular activities
BSY240_433	COG2833	Protein of unknown function (DUF455)
BSY240_4330	COG0617	tRNA 3'-terminal CCA addition
BSY240_4331	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY240_4334	COG0408	coproporphyrinogen oxidase activity
BSY240_4338	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSY240_4339	COG1132	(ABC) transporter
BSY240_434	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSY240_4344	COG1132	(ABC) transporter
BSY240_4347	COG2857	Cytochrome c1
BSY240_4347	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSY240_4348	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSY240_4349	COG1280	lysine exporter protein (LysE YggA)
BSY240_4351	COG0386	Belongs to the glutathione peroxidase family
BSY240_4356	COG0012	GTP binding
BSY240_4357	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSY240_4359	COG0251	oxidation-reduction process
BSY240_436	COG2099	Precorrin-6x reductase
BSY240_4362	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY240_4363	COG0193	aminoacyl-tRNA hydrolase activity
BSY240_4366	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSY240_4367	COG3300	MHYT domain
BSY240_4367	COG5001	Diguanylate cyclase
BSY240_4369	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_4371	COG0840	transmembrane signaling receptor activity
BSY240_4373	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSY240_4378	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSY240_4382	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY240_4383	COG2205	protein histidine kinase activity
BSY240_4384	COG0745	RESPONSE REGULATOR receiver
BSY240_4385	COG1846	Transcriptional regulator
BSY240_4387	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY240_4389	COG1278	Cold shock
BSY240_4390	COG2133	pyrroloquinoline quinone binding
BSY240_4393	COG2133	pyrroloquinoline quinone binding
BSY240_4400	COG1902	pentaerythritol trinitrate reductase activity
BSY240_4402	COG0583	DNA-binding transcription factor activity
BSY240_4403	COG0492	ferredoxin-NADP+ reductase activity
BSY240_4404	COG1522	sequence-specific DNA binding
BSY240_4407	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY240_4411	COG0745	RESPONSE REGULATOR receiver
BSY240_4412	COG5002	protein histidine kinase activity
BSY240_4417	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSY240_4420	COG0840	transmembrane signaling receptor activity
BSY240_4426	COG2321	neutral zinc metallopeptidase
BSY240_4428	COG0534	Mate efflux family protein
BSY240_4429	COG0505	Belongs to the CarA family
BSY240_443	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY240_4433	COG0358	DNA primase activity
BSY240_4435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY240_4439	COG1473	amidohydrolase
BSY240_444	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY240_4443	COG4702	Belongs to the UPF0303 family
BSY240_4444	COG0432	Pfam Uncharacterised protein family UPF0047
BSY240_445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY240_4450	COG4172	Belongs to the ABC transporter superfamily
BSY240_4451	COG0405	Gamma-glutamyltransferase
BSY240_4461	COG0402	S-adenosylhomocysteine deaminase activity
BSY240_4462	COG2207	Transcriptional regulator
BSY240_4463	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY240_4464	COG1136	(ABC) transporter
BSY240_447	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSY240_4477	COG3177	Filamentation induced by cAMP protein fic
BSY240_4478	COG0583	DNA-binding transcription factor activity
BSY240_4479	COG0625	glutathione transferase activity
BSY240_4480	COG1017	nitric oxide dioxygenase activity
BSY240_4480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY240_4481	COG0702	epimerase
BSY240_4484	COG1505	serine-type exopeptidase activity
BSY240_4487	COG5002	protein histidine kinase activity
BSY240_4488	COG0745	RESPONSE REGULATOR receiver
BSY240_4492	COG4221	oxidoreductase activity
BSY240_4495	COG0667	Aldo Keto reductase
BSY240_4497	COG2207	Transcriptional regulator
BSY240_4500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_4502	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY240_4502	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY240_4503	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY240_4505	COG1414	Transcriptional regulator
BSY240_4507	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BSY240_4510	COG1802	Transcriptional regulator
BSY240_4511	COG0129	dihydroxy-acid dehydratase activity
BSY240_4512	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_4513	COG1879	ABC-type sugar transport system periplasmic component
BSY240_4514	COG1129	ABC transporter
BSY240_4515	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_4516	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_4520	COG1396	sequence-specific DNA binding
BSY240_4521	COG3550	peptidyl-serine autophosphorylation
BSY240_4523	COG1063	alcohol dehydrogenase
BSY240_4524	COG3284	Transcriptional regulator
BSY240_4526	COG0583	DNA-binding transcription factor activity
BSY240_4527	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSY240_4528	COG0511	ligase activity, forming carbon-carbon bonds
BSY240_4529	COG0439	Biotin carboxylase
BSY240_4531	COG1984	allophanate hydrolase subunit 2
BSY240_4532	COG1879	ABC-type sugar transport system periplasmic component
BSY240_4533	COG1129	ABC transporter
BSY240_4534	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_4539	COG4227	nucleotidyltransferase activity
BSY240_4540	COG3550	peptidyl-serine autophosphorylation
BSY240_4549	COG1278	Cold shock
BSY240_4550	COG3620	sequence-specific DNA binding
BSY240_4551	COG0210	DNA helicase
BSY240_4553	COG0583	DNA-binding transcription factor activity
BSY240_4562	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BSY240_4567	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSY240_4568	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSY240_4569	COG0367	asparagine synthase
BSY240_4570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSY240_4570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY240_4574	COG1132	(ABC) transporter
BSY240_4577	COG2264	protein methyltransferase activity
BSY240_4583	COG0367	asparagine synthase
BSY240_4590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSY240_4592	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSY240_4593	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY240_4593	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BSY240_460	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BSY240_4602	COG0667	Aldo Keto reductase
BSY240_4607	COG1129	ABC transporter
BSY240_4608	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_4609	COG2376	Dihydroxyacetone kinase
BSY240_4611	COG1069	ribulokinase activity
BSY240_4613	COG4948	Mandelate Racemase Muconate Lactonizing
BSY240_4617	COG0492	ferredoxin-NADP+ reductase activity
BSY240_462	COG3706	GGDEF domain
BSY240_4625	COG2207	Transcriptional regulator
BSY240_4625	COG3708	Transcriptional regulator
BSY240_4628	COG3795	YCII-related domain
BSY240_4629	COG3795	YCII-related domain
BSY240_4632	COG2205	protein histidine kinase activity
BSY240_4633	COG0745	RESPONSE REGULATOR receiver
BSY240_4638	COG0577	efflux transmembrane transporter activity
BSY240_4638	COG1136	(ABC) transporter
BSY240_4652	COG1609	Transcriptional regulator
BSY240_4656	COG3842	ATPase activity
BSY240_4659	COG2963	transposase activity
BSY240_466	COG0395	ABC-type sugar transport system, permease component
BSY240_4665	COG1396	sequence-specific DNA binding
BSY240_4666	COG3706	GGDEF domain
BSY240_4667	COG2801	Transposase and inactivated derivatives
BSY240_467	COG3842	ATPase activity
BSY240_4671	COG5489	Protein of unknown function (DUF736)
BSY240_4672	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSY240_4675	COG3831	ATPase activity
BSY240_4676	COG3505	Type IV secretory pathway VirD4
BSY240_4679	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY240_4680	COG4959	Type IV secretory pathway protease TraF
BSY240_4681	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY240_4685	COG1968	undecaprenyl-diphosphatase activity
BSY240_4690	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSY240_470	COG0673	inositol 2-dehydrogenase activity
BSY240_4702	COG0489	protein tyrosine kinase activity
BSY240_4703	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSY240_4704	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY240_471	COG0667	Aldo Keto reductase
BSY240_4712	COG3547	Transposase (IS116 IS110 IS902 family)
BSY240_4717	COG2963	transposase activity
BSY240_472	COG3507	Belongs to the glycosyl hydrolase 43 family
BSY240_4723	COG2826	transposase and inactivated derivatives, IS30 family
BSY240_4724	COG0583	DNA-binding transcription factor activity
BSY240_4725	COG1396	sequence-specific DNA binding
BSY240_4727	COG1176	ABC-type spermidine putrescine transport system, permease component I
BSY240_4728	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BSY240_4729	COG3842	ATPase activity
BSY240_473	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSY240_4732	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY240_474	COG1671	Belongs to the UPF0178 family
BSY240_4744	COG1335	isochorismatase
BSY240_4755	COG0745	RESPONSE REGULATOR receiver
BSY240_476	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSY240_4760	COG3504	Conjugal transfer protein
BSY240_4761	COG3701	Conjugal transfer protein
BSY240_4762	COG3846	protein secretion by the type IV secretion system
BSY240_4763	COG5314	conjugation
BSY240_4764	COG3451	type IV secretory pathway VirB4
BSY240_4765	COG5268	conjugation
BSY240_4766	COG3838	Conjugal transfer protein Trbc
BSY240_4767	COG4962	Type ii secretion system protein e
BSY240_4769	COG1192	Involved in chromosome partitioning
BSY240_4770	COG1475	DNA binding
BSY240_4771	COG0640	Transcriptional regulator
BSY240_4772	COG0840	transmembrane signaling receptor activity
BSY240_481	COG0321	lipoyl(octanoyl) transferase activity
BSY240_484	COG1028	Short-chain dehydrogenase reductase Sdr
BSY240_487	COG0242	peptide deformylase activity
BSY240_488	COG2239	Acts as a magnesium transporter
BSY240_493	COG1760	l-serine dehydratase
BSY240_497	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSY240_499	COG0484	heat shock protein binding
BSY240_505	COG0556	nucleotide-excision repair
BSY240_51	COG0765	amino acid transport
BSY240_511	COG1607	acyl-coa hydrolase
BSY240_512	COG0840	transmembrane signaling receptor activity
BSY240_514	COG0730	response to heat
BSY240_519	COG0583	DNA-binding transcription factor activity
BSY240_52	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY240_521	COG0406	alpha-ribazole phosphatase activity
BSY240_523	COG1309	transcriptional regulator
BSY240_525	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSY240_528	COG1410	methionine synthase
BSY240_528	COG0646	methionine synthase
BSY240_53	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSY240_538	COG5012	cobalamin binding
BSY240_539	COG5598	trimethylamine methyltransferase
BSY240_54	COG1012	belongs to the aldehyde dehydrogenase family
BSY240_542	COG3698	Phosphodiester glycosidase
BSY240_544	COG1136	(ABC) transporter
BSY240_544	COG0577	efflux transmembrane transporter activity
BSY240_545	COG1136	(ABC) transporter
BSY240_545	COG0577	efflux transmembrane transporter activity
BSY240_546	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY240_547	COG1733	regulation of RNA biosynthetic process
BSY240_549	COG3485	protocatechuate 3,4-dioxygenase
BSY240_550	COG0582	viral genome integration into host DNA
BSY240_554	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BSY240_563	COG0785	Cytochrome C biogenesis protein
BSY240_564	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY240_565	COG0679	Auxin Efflux Carrier
BSY240_566	COG1183	phosphatidylcholine synthase activity
BSY240_571	COG2186	Transcriptional regulator
BSY240_572	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSY240_573	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY240_575	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSY240_577	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSY240_578	COG0697	spore germination
BSY240_580	COG4166	transmembrane transport
BSY240_584	COG0174	glutamine synthetase
BSY240_585	COG0347	Belongs to the P(II) protein family
BSY240_586	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSY240_586	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSY240_589	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSY240_59	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BSY240_590	COG0629	single-stranded DNA binding
BSY240_596	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY240_598	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY240_607	COG4191	Histidine kinase
BSY240_610	COG2095	MarC family integral membrane protein
BSY240_611	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSY240_615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSY240_616	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSY240_617	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BSY240_618	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSY240_619	COG0343	queuine tRNA-ribosyltransferase activity
BSY240_62	COG1609	Transcriptional regulator
BSY240_621	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY240_622	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY240_623	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY240_627	COG2801	Transposase and inactivated derivatives
BSY240_629	COG0084	hydrolase, TatD family'
BSY240_63	COG1879	ABC-type sugar transport system periplasmic component
BSY240_630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY240_632	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSY240_633	COG1686	Belongs to the peptidase S11 family
BSY240_64	COG1129	ABC transporter
BSY240_643	COG0683	leucine binding
BSY240_644	COG0784	Response regulator, receiver
BSY240_644	COG2198	Histidine kinase
BSY240_644	COG5002	protein histidine kinase activity
BSY240_645	COG0745	RESPONSE REGULATOR receiver
BSY240_645	COG3706	GGDEF domain
BSY240_65	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY240_650	COG0542	response to heat
BSY240_652	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSY240_652	COG3608	succinylglutamate desuccinylase aspartoacylase
BSY240_659	COG4176	ABC-type proline glycine betaine transport system permease component
BSY240_66	COG1735	metal-dependent hydrolase with the TIM-barrel fold
BSY240_660	COG3448	diguanylate cyclase activity
BSY240_660	COG4175	Glycine betaine
BSY240_661	COG1410	methionine synthase
BSY240_661	COG0646	methionine synthase
BSY240_667	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSY240_667	COG1648	precorrin-2 dehydrogenase activity
BSY240_669	COG3956	TIGRFAM MazG family protein
BSY240_670	COG1719	4-vinyl reductase, 4VR
BSY240_672	COG1032	radical SAM domain protein
BSY240_673	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSY240_674	COG1923	regulation of RNA biosynthetic process
BSY240_676	COG0569	domain protein
BSY240_677	COG2204	response regulator
BSY240_678	COG5000	phosphorelay sensor kinase activity
BSY240_679	COG2204	response regulator
BSY240_68	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY240_680	COG3852	Histidine kinase
BSY240_682	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSY240_682	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSY240_686	COG3093	addiction module antidote protein HigA
BSY240_687	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSY240_689	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY240_69	COG0434	BtpA family
BSY240_692	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY240_693	COG0022	dehydrogenase e1 component
BSY240_693	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY240_694	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSY240_696	COG0148	phosphopyruvate hydratase activity
BSY240_697	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BSY240_701	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSY240_704	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSY240_705	COG0134	indole-3-glycerol-phosphate synthase activity
BSY240_706	COG0315	cyclic pyranopterin monophosphate synthase activity
BSY240_707	COG0303	'Molybdopterin
BSY240_708	COG0504	CTP synthase activity
BSY240_709	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSY240_710	COG0149	triose-phosphate isomerase activity
BSY240_712	COG0187	DNA topoisomerase II activity
BSY240_713	COG0628	permease
BSY240_717	COG0778	Nitroreductase
BSY240_720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSY240_722	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSY240_724	COG0302	gtp cyclohydrolase
BSY240_725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSY240_726	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSY240_727	COG0516	GMP reductase activity
BSY240_727	COG0517	IMP dehydrogenase activity
BSY240_73	COG0840	transmembrane signaling receptor activity
BSY240_73	COG3290	protein histidine kinase activity
BSY240_732	COG1686	Belongs to the peptidase S11 family
BSY240_735	COG0735	belongs to the Fur family
BSY240_736	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BSY240_737	COG1121	(ABC) transporter
BSY240_738	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BSY240_739	COG0523	cobalamin synthesis protein
BSY240_740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY240_741	COG3494	Protein of unknown function (DUF1009)
BSY240_742	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY240_743	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY240_744	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY240_745	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSY240_746	COG0750	zinc metalloprotease
BSY240_748	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSY240_749	COG0233	cytoplasmic translational termination
BSY240_75	COG2132	Multicopper oxidase
BSY240_750	COG0528	UMP kinase activity
BSY240_751	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSY240_752	COG0052	Belongs to the universal ribosomal protein uS2 family
BSY240_757	COG0537	adenosine 5'-monophosphoramidase activity
BSY240_762	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSY240_766	COG1024	Enoyl-CoA hydratase
BSY240_767	COG2267	carboxylic ester hydrolase activity
BSY240_770	COG0626	cystathionine gamma-synthase activity
BSY240_771	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY240_772	COG4597	amino acid ABC transporter
BSY240_773	COG0765	amino acid transport
BSY240_774	COG1126	abc transporter atp-binding protein
BSY240_780	COG1278	Cold shock
BSY240_789	COG0436	Aminotransferase
BSY240_791	COG3243	poly(R)-hydroxyalkanoic acid synthase
BSY240_792	COG1489	DNA binding
BSY240_793	COG0024	Methionine aminopeptidase
BSY240_794	COG2003	Belongs to the UPF0758 family
BSY240_797	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BSY240_798	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSY240_803	COG1957	nucleoside hydrolase
BSY240_804	COG2875	Belongs to the precorrin methyltransferase family
BSY240_810	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
BSY240_82	COG3300	MHYT domain
BSY240_82	COG5001	Diguanylate cyclase
BSY240_820	COG0546	phosphoglycolate phosphatase activity
BSY240_821	COG0564	pseudouridine synthase activity
BSY240_822	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSY240_827	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY240_828	COG0509	glycine decarboxylation via glycine cleavage system
BSY240_829	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY240_829	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY240_838	COG0316	Belongs to the HesB IscA family
BSY240_839	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY240_84	COG0840	transmembrane signaling receptor activity
BSY240_840	COG1335	isochorismatase
BSY240_841	COG0251	oxidation-reduction process
BSY240_842	COG2267	carboxylic ester hydrolase activity
BSY240_843	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY240_844	COG2151	metal-sulfur cluster biosynthetic enzyme
BSY240_845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSY240_846	COG0719	Fe-S assembly protein
BSY240_847	COG0396	ATPase activity
BSY240_849	COG0719	Fe-S assembly protein
BSY240_850	COG1104	cysteine desulfurase activity
BSY240_851	COG2945	thiolester hydrolase activity
BSY240_854	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSY240_856	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSY240_858	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSY240_86	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
BSY240_866	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY240_867	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSY240_868	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSY240_869	COG0805	protein transport
BSY240_870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY240_871	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY240_873	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSY240_878	COG0018	arginyl-trna synthetase
BSY240_879	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BSY240_880	COG0316	Belongs to the HesB IscA family
BSY240_882	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BSY240_885	COG0525	valine-tRNA ligase activity
BSY240_887	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY240_893	COG0415	Belongs to the DNA photolyase family
BSY240_894	COG2161	toxin-antitoxin pair type II binding
BSY240_895	COG4115	mRNA cleavage
BSY240_898	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSY240_899	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY240_900	COG2897	thiosulfate sulfurtransferase activity
BSY240_905	COG0686	Belongs to the AlaDH PNT family
BSY240_906	COG1522	sequence-specific DNA binding
BSY240_909	COG0737	Belongs to the 5'-nucleotidase family
BSY240_910	COG0583	DNA-binding transcription factor activity
BSY240_911	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSY240_912	COG3300	MHYT domain
BSY240_912	COG5001	Diguanylate cyclase
BSY240_914	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSY240_916	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSY240_918	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY240_920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY240_923	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSY240_924	COG1546	Belongs to the CinA family
BSY240_924	COG1058	Belongs to the CinA family
BSY240_926	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BSY240_933	COG0702	epimerase
BSY240_934	COG0840	transmembrane signaling receptor activity
BSY240_935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSY240_941	COG1231	oxidoreductase activity
BSY240_943	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSY240_944	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY240_947	COG1017	nitric oxide dioxygenase activity
BSY240_947	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY240_95	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY240_951	COG0235	Class ii aldolase
BSY240_952	COG0129	dihydroxy-acid dehydratase activity
BSY240_954	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY240_955	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BSY240_959	COG3739	integral membrane protein
BSY240_960	COG3795	YCII-related domain
BSY240_962	COG4941	Belongs to the sigma-70 factor family
BSY240_964	COG0203	ribosomal protein L17
BSY240_965	COG0202	RNA polymerase activity
BSY240_966	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSY240_967	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSY240_968	COG0563	adenylate kinase activity
BSY240_970	COG0200	Binds to the 23S rRNA
BSY240_971	COG1841	ribosomal large subunit assembly
BSY240_972	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSY240_973	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSY240_974	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSY240_975	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSY240_976	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSY240_977	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSY240_978	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSY240_979	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSY240_980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSY240_981	COG0255	Belongs to the universal ribosomal protein uL29 family
BSY240_982	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSY240_983	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSY240_984	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSY240_985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSY240_986	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSY240_987	COG0089	rRNA binding
BSY240_988	COG0088	Forms part of the polypeptide exit tunnel
BSY240_989	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSY240_990	COG0051	transcription antitermination factor activity, RNA binding
BSY240_991	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY240_992	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSY240_993	COG0049	tRNA binding
BSY240_994	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSY240_996	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSY240_997	COG0085	RNA polymerase activity
BSY240_998	COG0222	ribosome binding
BSY240_999	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors