locus-tag	class	description
J5276_00020	COG0501	Belongs to the peptidase M48B family
J5276_00025	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J5276_00025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5276_00035	COG0138	bifunctional purine biosynthesis protein purh
J5276_00040	COG2721	sulfolactate sulfo-lyase activity
J5276_00045	COG2186	Transcriptional regulator
J5276_00050	COG1129	ABC transporter
J5276_00055	COG4214	carbohydrate transport
J5276_00075	COG1063	alcohol dehydrogenase
J5276_00080	COG0246	Mannitol dehydrogenase
J5276_00085	COG3254	rhamnose metabolic process
J5276_00090	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_00105	COG1492	cobalamin metabolic process
J5276_00170	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
J5276_00175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5276_00175	COG1648	precorrin-2 dehydrogenase activity
J5276_00180	COG1797	cobyrinic acid a,c-diamide synthase activity
J5276_00185	COG1858	cytochrome C peroxidase
J5276_00190	COG0473	3-isopropylmalate dehydrogenase activity
J5276_00195	COG0066	3-isopropylmalate dehydratase activity
J5276_00220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J5276_00225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J5276_00240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J5276_00245	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J5276_00250	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J5276_00255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J5276_00260	COG0799	negative regulation of ribosome biogenesis
J5276_00265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J5276_00275	COG0793	Belongs to the peptidase S41A family
J5276_00285	COG0494	nUDIX hydrolase
J5276_00300	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_00315	COG2270	Major facilitator Superfamily
J5276_00320	COG2902	Dehydrogenase
J5276_00325	COG1329	Transcriptional regulator
J5276_00335	COG0745	RESPONSE REGULATOR receiver
J5276_00350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J5276_00355	COG1674	ftsk spoiiie
J5276_00360	COG0004	ammonium transporteR
J5276_00365	COG0347	Belongs to the P(II) protein family
J5276_00370	COG1946	Acyl-CoA thioesterase
J5276_00375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5276_00385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5276_00390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5276_00405	COG0495	leucyl-tRNA aminoacylation
J5276_00420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5276_00425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_00430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_00435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5276_00445	COG2186	Transcriptional regulator
J5276_00450	COG0277	FAD linked oxidase domain protein
J5276_00455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_00460	COG2084	Dehydrogenase
J5276_00465	COG0129	dihydroxy-acid dehydratase activity
J5276_00475	COG0579	oxidoreductase
J5276_00480	COG1473	amidohydrolase
J5276_00485	COG3459	Glycosyltransferase 36 associated
J5276_00490	COG1132	(ABC) transporter
J5276_00495	COG2197	response regulator
J5276_00500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J5276_00505	COG1349	DNA-binding transcription factor activity
J5276_00510	COG2223	nitrite transmembrane transporter activity
J5276_00515	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J5276_00520	COG2885	chlorophyll binding
J5276_00525	COG0142	geranyltranstransferase activity
J5276_00530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J5276_00540	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J5276_00550	COG0488	(ABC) transporter
J5276_00570	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
J5276_00580	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J5276_00595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_00600	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
J5276_00605	COG0335	large ribosomal subunit rRNA binding
J5276_00615	COG0336	Belongs to the RNA methyltransferase TrmD family
J5276_00620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J5276_00625	COG0228	four-way junction DNA binding
J5276_00630	COG1605	Chorismate mutase
J5276_00630	COG0287	Prephenate dehydrogenase
J5276_00635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J5276_00645	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J5276_00650	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5276_00655	COG0552	protein localization to endoplasmic reticulum
J5276_00660	COG2917	probably involved in intracellular septation
J5276_00685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5276_00690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J5276_00695	COG4133	protoheme IX ABC transporter activity
J5276_00700	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J5276_00715	COG0670	Belongs to the BI1 family
J5276_00725	COG4181	ATPase activity
J5276_00735	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
J5276_00740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J5276_00745	COG2154	pterin-4-alpha-carbinolamine dehydratase
J5276_00760	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J5276_00770	COG4120	Belongs to the binding-protein-dependent transport system permease family
J5276_00775	COG1122	ATPase activity
J5276_00780	COG1280	lysine exporter protein (LysE YggA)
J5276_00790	COG0137	argininosuccinate synthase activity
J5276_00800	COG1846	Transcriptional regulator
J5276_00810	COG0339	signal peptide processing
J5276_00815	COG1217	gtp-binding protein TYPA
J5276_00825	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J5276_00830	COG1872	DUF167
J5276_00870	COG0181	hydroxymethylbilane synthase activity
J5276_00875	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J5276_00880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J5276_00895	COG2264	protein methyltransferase activity
J5276_00930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J5276_00935	COG0039	L-malate dehydrogenase activity
J5276_00940	COG0045	succinate-CoA ligase (ADP-forming) activity
J5276_00945	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
J5276_00950	COG0567	Dehydrogenase, E1 component
J5276_00955	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5276_00965	COG1280	lysine exporter protein (LysE YggA)
J5276_00990	COG4974	Belongs to the 'phage' integrase family
J5276_01005	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J5276_01010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J5276_01015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J5276_01020	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J5276_01025	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J5276_01030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J5276_01040	COG0835	chemotaxis
J5276_01050	COG0729	surface antigen
J5276_01060	COG0156	8-amino-7-oxononanoate synthase activity
J5276_01065	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J5276_01070	COG0671	phosphoesterase, PA-phosphatase related
J5276_01080	COG1940	carbohydrate kinase activity
J5276_01085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J5276_01090	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J5276_01095	COG2188	Transcriptional regulator
J5276_01110	COG0395	ABC-type sugar transport system, permease component
J5276_01120	COG3842	ATPase activity
J5276_01130	COG1737	Transcriptional regulator
J5276_01135	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_01150	COG2814	Major facilitator Superfamily
J5276_01155	COG3142	Participates in the control of copper homeostasis
J5276_01160	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5276_01165	COG0438	transferase activity, transferring glycosyl groups
J5276_01175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_01180	COG0601	transmembrane transport
J5276_01185	COG4166	transmembrane transport
J5276_01205	COG0438	transferase activity, transferring glycosyl groups
J5276_01230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5276_01235	COG1132	(ABC) transporter
J5276_01255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5276_01265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_01270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J5276_01285	COG2022	thiamine diphosphate biosynthetic process
J5276_01300	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J5276_01305	COG4149	molybdate abc transporter
J5276_01310	COG0725	ABC transporter, periplasmic molybdate-binding protein
J5276_01315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_01320	COG0583	DNA-binding transcription factor activity
J5276_01340	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J5276_01345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J5276_01355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_01360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_01370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5276_01405	COG1017	nitric oxide dioxygenase activity
J5276_01405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5276_01415	COG0277	FAD linked oxidase domain protein
J5276_01475	COG2198	Histidine kinase
J5276_01475	COG0643	Histidine kinase
J5276_01480	COG0835	chemotaxis
J5276_01485	COG0840	transmembrane signaling receptor activity
J5276_01490	COG0835	chemotaxis
J5276_01495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5276_01500	COG2201	protein-glutamate methylesterase activity
J5276_01505	COG1192	Involved in chromosome partitioning
J5276_01525	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_01530	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_01540	COG3842	ATPase activity
J5276_01545	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_01545	COG1902	pentaerythritol trinitrate reductase activity
J5276_01555	COG0745	RESPONSE REGULATOR receiver
J5276_01585	COG1960	acyl-CoA dehydrogenase activity
J5276_01590	COG2159	amidohydrolase
J5276_01630	COG0392	lysyltransferase activity
J5276_01630	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J5276_01650	COG0601	transmembrane transport
J5276_01655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_01660	COG0444	Belongs to the ABC transporter superfamily
J5276_01665	COG4608	Belongs to the ABC transporter superfamily
J5276_01680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5276_01690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_01695	COG3842	ATPase activity
J5276_01700	COG0395	ABC-type sugar transport system, permease component
J5276_01705	COG1175	transmembrane transport
J5276_01720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_01730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_01735	COG1335	isochorismatase
J5276_01740	COG0251	oxidation-reduction process
J5276_01745	COG2267	carboxylic ester hydrolase activity
J5276_01750	COG0778	Nitroreductase
J5276_01755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_01760	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J5276_01775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J5276_01785	COG0288	reversible hydration of carbon dioxide
J5276_01790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
J5276_01795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5276_01815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_01820	COG0657	acetylesterase activity
J5276_01825	COG0583	DNA-binding transcription factor activity
J5276_01835	COG2814	Major facilitator Superfamily
J5276_01840	COG0656	L-ascorbic acid biosynthetic process
J5276_01845	COG0840	transmembrane signaling receptor activity
J5276_01845	COG2972	Histidine kinase
J5276_01860	COG0783	Belongs to the Dps family
J5276_01865	COG4604	ABC transporter, ATP-binding protein
J5276_01870	COG4605	iron ion homeostasis
J5276_01875	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_01915	COG2205	protein histidine kinase activity
J5276_01935	COG3721	Heme iron utilization protein
J5276_01945	COG4558	Periplasmic binding protein
J5276_01950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_01955	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5276_01960	COG2832	Protein of unknown function (DUF454)
J5276_01970	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J5276_01980	COG0346	lactoylglutathione lyase activity
J5276_02005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J5276_02015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5276_02030	COG0564	pseudouridine synthase activity
J5276_02105	COG1218	3'(2'),5'-bisphosphate nucleotidase
J5276_02150	COG0784	Response regulator, receiver
J5276_02150	COG5002	protein histidine kinase activity
J5276_02150	COG2198	Histidine kinase
J5276_02155	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_02160	COG0174	glutamine synthetase
J5276_02175	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5276_02185	COG0411	ABC transporter
J5276_02200	COG0829	nickel cation binding
J5276_02205	COG0831	urea catabolic process
J5276_02210	COG3813	Protein conserved in bacteria
J5276_02215	COG0832	Belongs to the urease beta subunit family
J5276_02225	COG3755	Protein conserved in bacteria
J5276_02230	COG1442	glycosyl transferase family 8
J5276_02235	COG0804	urea catabolic process
J5276_02250	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
J5276_02255	COG0830	nickel cation binding
J5276_02260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
J5276_02290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_02295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_02305	COG0494	nUDIX hydrolase
J5276_02320	COG1309	transcriptional regulator
J5276_02340	COG2346	COG2346, Truncated hemoglobins
J5276_02345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5276_02360	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
J5276_02375	COG1215	transferase activity, transferring glycosyl groups
J5276_02405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_02425	COG0840	transmembrane signaling receptor activity
J5276_02460	COG4213	ABC transporter substrate-binding protein
J5276_02465	COG1129	ABC transporter
J5276_02470	COG4214	carbohydrate transport
J5276_02500	COG1305	Transglutaminase-like
J5276_02510	COG2308	Evidence 4 Homologs of previously reported genes of
J5276_02520	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_02525	COG2259	Doxx family
J5276_02535	COG0513	Belongs to the DEAD box helicase family
J5276_02540	COG5002	protein histidine kinase activity
J5276_02540	COG0784	Response regulator, receiver
J5276_02540	COG2205	protein histidine kinase activity
J5276_02545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_02545	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J5276_02555	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J5276_02580	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J5276_02585	COG2351	hydroxyisourate hydrolase activity
J5276_02595	COG1686	Belongs to the peptidase S11 family
J5276_02600	COG1309	transcriptional regulator
J5276_02625	COG0402	S-adenosylhomocysteine deaminase activity
J5276_02640	COG0583	DNA-binding transcription factor activity
J5276_02650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5276_02660	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_02670	COG0024	Methionine aminopeptidase
J5276_02680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J5276_02700	COG1160	GTP binding
J5276_02715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_02720	COG0366	Alpha amylase catalytic
J5276_02730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J5276_02740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5276_02740	COG0512	Glutamine amidotransferase of anthranilate synthase
J5276_02755	COG2862	Uncharacterized protein family, UPF0114
J5276_02775	COG1435	thymidine kinase activity
J5276_02790	COG4175	Glycine betaine
J5276_02815	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J5276_02820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J5276_02835	COG0740	serine-type endopeptidase activity
J5276_02850	COG4944	Protein of unknown function (DUF1109)
J5276_02855	COG3135	benzoate transporter
J5276_02860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J5276_02875	COG0435	Glutathione S-transferase
J5276_02885	COG0477	Major facilitator Superfamily
J5276_02890	COG0454	-acetyltransferase
J5276_02910	COG0714	Associated with various cellular activities
J5276_02925	COG0617	tRNA 3'-terminal CCA addition
J5276_02940	COG0408	coproporphyrinogen oxidase activity
J5276_02955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J5276_02965	COG1132	(ABC) transporter
J5276_02970	COG1132	(ABC) transporter
J5276_02990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J5276_02990	COG2857	Cytochrome c1
J5276_03000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J5276_03005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5276_03025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5276_03035	COG0193	aminoacyl-tRNA hydrolase activity
J5276_03045	COG5001	Diguanylate cyclase
J5276_03050	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J5276_03055	COG3300	MHYT domain
J5276_03055	COG5001	Diguanylate cyclase
J5276_03065	COG1012	belongs to the aldehyde dehydrogenase family
J5276_03070	COG0840	transmembrane signaling receptor activity
J5276_03085	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
J5276_03095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J5276_03110	COG1496	oxidoreductase activity
J5276_03120	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J5276_03140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5276_03145	COG2205	protein histidine kinase activity
J5276_03150	COG0745	RESPONSE REGULATOR receiver
J5276_03155	COG1846	Transcriptional regulator
J5276_03165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_03170	COG1278	Cold shock
J5276_03185	COG2199	diguanylate cyclase activity
J5276_03185	COG2200	EAL domain
J5276_03190	COG0436	Aminotransferase
J5276_03195	COG0387	Pfam Sodium calcium exchanger
J5276_03220	COG1902	pentaerythritol trinitrate reductase activity
J5276_03230	COG0583	DNA-binding transcription factor activity
J5276_03235	COG0492	ferredoxin-NADP+ reductase activity
J5276_03240	COG1522	sequence-specific DNA binding
J5276_03250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_03260	COG1573	uracil-dna glycosylase
J5276_03265	COG3706	GGDEF domain
J5276_03270	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J5276_03285	COG2321	neutral zinc metallopeptidase
J5276_03300	COG0534	Mate efflux family protein
J5276_03305	COG0505	Belongs to the CarA family
J5276_03315	COG0358	DNA primase activity
J5276_03320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J5276_03335	COG0432	Pfam Uncharacterised protein family UPF0047
J5276_03345	COG2968	Membrane
J5276_03405	COG3842	ATPase activity
J5276_03425	COG1737	Transcriptional regulator
J5276_03435	COG0531	amino acid
J5276_03440	COG0174	glutamine synthetase
J5276_03445	COG1012	belongs to the aldehyde dehydrogenase family
J5276_03470	COG2814	Major facilitator Superfamily
J5276_03475	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_03490	COG0251	oxidation-reduction process
J5276_03505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J5276_03510	COG2267	carboxylic ester hydrolase activity
J5276_03520	COG2226	methyltransferase
J5276_03540	COG4106	trans-aconitate 2-methyltransferase activity
J5276_03570	COG3023	N-Acetylmuramoyl-L-alanine amidase
J5276_03595	COG2001	Belongs to the MraZ family
J5276_03600	COG0275	rRNA processing
J5276_03615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J5276_03625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5276_03630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J5276_03640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J5276_03645	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J5276_03650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J5276_03660	COG0477	Major facilitator Superfamily
J5276_03665	COG1181	Belongs to the D-alanine--D-alanine ligase family
J5276_03670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J5276_03675	COG0849	cell division
J5276_03680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5276_03690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5276_03695	COG0497	DNA recombination
J5276_03700	COG1280	lysine exporter protein (LysE YggA)
J5276_03705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J5276_03715	COG1247	-acetyltransferase
J5276_03725	COG0583	DNA-binding transcription factor activity
J5276_03730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J5276_03740	COG0835	chemotaxis
J5276_03750	COG1999	signal sequence binding
J5276_03755	COG2264	protein methyltransferase activity
J5276_03765	COG0006	proline dipeptidase activity
J5276_03785	COG1335	isochorismatase
J5276_03840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_03845	COG0277	FAD linked oxidase domain protein
J5276_03885	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J5276_03895	COG0330	HflC and HflK could
J5276_03900	COG0330	HflC and HflK could
J5276_03920	COG0560	Phosphoserine phosphatase
J5276_03920	COG3830	Belongs to the UPF0237 family
J5276_03925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J5276_03935	COG0028	Belongs to the TPP enzyme family
J5276_03940	COG0440	acetolactate synthase activity
J5276_03955	COG0656	L-ascorbic acid biosynthetic process
J5276_03995	COG1090	epimerase
J5276_04000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5276_04005	COG2197	response regulator
J5276_04010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J5276_04015	COG1252	NADH dehydrogenase
J5276_04020	COG1064	alcohol dehydrogenase
J5276_04025	COG2207	Transcriptional regulator
J5276_04035	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J5276_04050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_04055	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_04065	COG3842	ATPase activity
J5276_04075	COG3706	GGDEF domain
J5276_04090	COG0484	heat shock protein binding
J5276_04110	COG2382	esterase
J5276_04115	COG0556	nucleotide-excision repair
J5276_04125	COG1733	regulation of RNA biosynthetic process
J5276_04130	COG2910	NAD(P)H-binding
J5276_04155	COG1607	acyl-coa hydrolase
J5276_04160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5276_04190	COG0861	Integral membrane protein TerC family
J5276_04195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5276_04210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J5276_04220	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J5276_04225	COG0081	regulation of translation
J5276_04230	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J5276_04235	COG0222	ribosome binding
J5276_04245	COG0085	RNA polymerase activity
J5276_04250	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J5276_04265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J5276_04270	COG0049	tRNA binding
J5276_04275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J5276_04280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J5276_04285	COG0051	transcription antitermination factor activity, RNA binding
J5276_04290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J5276_04295	COG0088	Forms part of the polypeptide exit tunnel
J5276_04300	COG0089	rRNA binding
J5276_04305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J5276_04310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J5276_04315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J5276_04320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J5276_04325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J5276_04330	COG0255	Belongs to the universal ribosomal protein uL29 family
J5276_04335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J5276_04340	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J5276_04345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J5276_04350	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J5276_04355	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J5276_04360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J5276_04365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J5276_04370	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J5276_04375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J5276_04380	COG1841	ribosomal large subunit assembly
J5276_04385	COG0200	Binds to the 23S rRNA
J5276_04390	COG0201	protein transport
J5276_04395	COG0563	adenylate kinase activity
J5276_04400	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J5276_04405	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J5276_04410	COG0202	RNA polymerase activity
J5276_04415	COG0203	ribosomal protein L17
J5276_04425	COG3739	integral membrane protein
J5276_04435	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J5276_04440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J5276_04445	COG0129	dihydroxy-acid dehydratase activity
J5276_04460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5276_04465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J5276_04475	COG0840	transmembrane signaling receptor activity
J5276_04475	COG0840	transmembrane signaling receptor activity
J5276_04485	COG0730	response to heat
J5276_04490	COG1131	(ABC) transporter
J5276_04495	COG0842	Transport permease protein
J5276_04510	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J5276_04515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J5276_04525	COG2205	protein histidine kinase activity
J5276_04525	COG2202	Pas domain
J5276_04535	COG1573	uracil-dna glycosylase
J5276_04540	COG1522	sequence-specific DNA binding
J5276_04545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_04555	COG5425	PFAM Usg family protein
J5276_04565	COG4215	(ABC) transporter
J5276_04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_04580	COG2313	pseudouridylate synthase activity
J5276_04585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_04590	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J5276_04595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J5276_04610	COG0538	isocitrate dehydrogenase activity
J5276_04620	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
J5276_04625	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J5276_04635	COG1280	lysine exporter protein (LysE YggA)
J5276_04655	COG0861	Integral membrane protein TerC family
J5276_04660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J5276_04665	COG2066	Belongs to the glutaminase family
J5276_04670	COG0037	tRNA processing
J5276_04675	COG0483	inositol monophosphate 1-phosphatase activity
J5276_04680	COG0483	inositol monophosphate 1-phosphatase activity
J5276_04685	COG2814	Major facilitator Superfamily
J5276_04690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J5276_04710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5276_04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_04735	COG0047	phosphoribosylformylglycinamidine synthase activity
J5276_04740	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J5276_04745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J5276_04755	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J5276_04780	COG0513	Belongs to the DEAD box helicase family
J5276_04785	COG0739	heme binding
J5276_04790	COG2833	Protein of unknown function (DUF455)
J5276_04795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J5276_04805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J5276_04810	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J5276_04815	COG2945	thiolester hydrolase activity
J5276_04820	COG1104	cysteine desulfurase activity
J5276_04825	COG0719	Fe-S assembly protein
J5276_04830	COG0396	ATPase activity
J5276_04835	COG0719	Fe-S assembly protein
J5276_04840	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J5276_04845	COG2151	metal-sulfur cluster biosynthetic enzyme
J5276_04860	COG0577	efflux transmembrane transporter activity
J5276_04860	COG1136	(ABC) transporter
J5276_04865	COG1136	(ABC) transporter
J5276_04865	COG0577	efflux transmembrane transporter activity
J5276_04920	COG1278	Cold shock
J5276_04925	COG0346	lactoylglutathione lyase activity
J5276_05080	COG1061	Type III restriction enzyme res subunit
J5276_05180	COG0616	signal peptide processing
J5276_05240	COG3685	Protein conserved in bacteria
J5276_05375	COG0785	Cytochrome C biogenesis protein
J5276_05380	COG0679	Auxin Efflux Carrier
J5276_05385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5276_05390	COG1183	phosphatidylcholine synthase activity
J5276_05395	COG3845	ABC transporter
J5276_05400	COG4603	Belongs to the binding-protein-dependent transport system permease family
J5276_05405	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5276_05415	COG2186	Transcriptional regulator
J5276_05420	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5276_05425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J5276_05455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J5276_05465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J5276_05475	COG0697	spore germination
J5276_05505	COG0174	glutamine synthetase
J5276_05510	COG0347	Belongs to the P(II) protein family
J5276_05520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J5276_05520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J5276_05535	COG0583	DNA-binding transcription factor activity
J5276_05570	COG1760	l-serine dehydratase
J5276_05600	COG0516	GMP reductase activity
J5276_05600	COG0517	IMP dehydrogenase activity
J5276_05605	COG1752	Esterase of the alpha-beta hydrolase superfamily
J5276_05610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J5276_05615	COG0302	gtp cyclohydrolase
J5276_05625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J5276_05635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J5276_05670	COG0628	permease
J5276_05675	COG1132	(ABC) transporter
J5276_05685	COG1914	H( )-stimulated, divalent metal cation uptake system
J5276_05700	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J5276_05710	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
J5276_05715	COG0589	response to stress
J5276_05720	COG1058	Belongs to the CinA family
J5276_05720	COG1546	Belongs to the CinA family
J5276_05725	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5276_05910	COG1372	Participates in initiation and elongation during chromosome replication
J5276_05910	COG0305	Participates in initiation and elongation during chromosome replication
J5276_05935	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5276_05985	COG5410	chromosome segregation
J5276_06080	COG3645	SOS response
J5276_06080	COG3646	Phage regulatory protein
J5276_06120	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_06125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_06285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5276_06295	COG0525	valine-tRNA ligase activity
J5276_06320	COG0316	Belongs to the HesB IscA family
J5276_06325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J5276_06330	COG0018	arginyl-trna synthetase
J5276_06340	COG1472	Belongs to the glycosyl hydrolase 3 family
J5276_06345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J5276_06350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J5276_06355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5276_06360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J5276_06365	COG0805	protein transport
J5276_06370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J5276_06375	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J5276_06380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J5276_06385	COG0739	heme binding
J5276_06390	COG1763	Mo-molybdopterin cofactor biosynthetic process
J5276_06395	COG0746	molybdenum cofactor guanylyltransferase activity
J5276_06400	COG2814	Major facilitator Superfamily
J5276_06410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J5276_06420	COG0475	glutathione-regulated potassium exporter activity
J5276_06420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J5276_06430	COG3706	GGDEF domain
J5276_06435	COG0303	'Molybdopterin
J5276_06440	COG0315	cyclic pyranopterin monophosphate synthase activity
J5276_06445	COG0134	indole-3-glycerol-phosphate synthase activity
J5276_06450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5276_06465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J5276_06480	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J5276_06485	COG0343	queuine tRNA-ribosyltransferase activity
J5276_06490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J5276_06490	COG0512	Glutamine amidotransferase of anthranilate synthase
J5276_06515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J5276_06535	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
J5276_06555	COG0544	peptidyl-prolyl cis-trans isomerase activity
J5276_06585	COG1368	sulfuric ester hydrolase activity
J5276_06600	COG0823	Involved in the tonB-independent uptake of proteins
J5276_06605	COG0778	Nitroreductase
J5276_06615	COG0280	phosphate acetyltransferase
J5276_06615	COG0281	malic enzyme
J5276_06625	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_06630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J5276_06635	COG1127	ABC transporter
J5276_06700	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J5276_06700	COG3264	Mechanosensitive ion channel
J5276_06715	COG0745	RESPONSE REGULATOR receiver
J5276_06720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J5276_06725	COG0640	Transcriptional regulator
J5276_06735	COG0740	serine-type endopeptidase activity
J5276_06740	COG0187	DNA topoisomerase II activity
J5276_06750	COG0149	triose-phosphate isomerase activity
J5276_06760	COG0504	CTP synthase activity
J5276_06770	COG0114	fumarate hydratase activity
J5276_06780	COG0546	phosphoglycolate phosphatase activity
J5276_06785	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J5276_06800	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J5276_06815	COG2003	Belongs to the UPF0758 family
J5276_06820	COG0024	Methionine aminopeptidase
J5276_06825	COG1489	DNA binding
J5276_06830	COG3243	poly(R)-hydroxyalkanoic acid synthase
J5276_06845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5276_06850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_06855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5276_06865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5276_06895	COG0436	Aminotransferase
J5276_06910	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J5276_06925	COG1126	abc transporter atp-binding protein
J5276_06930	COG0765	amino acid transport
J5276_06935	COG4597	amino acid ABC transporter
J5276_06940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_06945	COG0626	cystathionine gamma-synthase activity
J5276_06960	COG0596	Alpha beta hydrolase
J5276_06975	COG2124	cytochrome p450
J5276_06995	COG1862	Preprotein translocase
J5276_07025	COG1064	alcohol dehydrogenase
J5276_07030	COG0321	lipoyl(octanoyl) transferase activity
J5276_07055	COG0242	peptide deformylase activity
J5276_07065	COG0243	molybdopterin cofactor binding
J5276_07070	COG2239	Acts as a magnesium transporter
J5276_07145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J5276_07155	COG0667	Aldo Keto reductase
J5276_07175	COG1121	(ABC) transporter
J5276_07180	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5276_07195	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_07200	COG3685	Protein conserved in bacteria
J5276_07210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J5276_07220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J5276_07225	COG0629	single-stranded DNA binding
J5276_07230	COG0517	IMP dehydrogenase activity
J5276_07230	COG0617	tRNA 3'-terminal CCA addition
J5276_07230	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J5276_07235	COG2095	MarC family integral membrane protein
J5276_07240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5276_07290	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J5276_07300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5276_07305	COG0084	hydrolase, TatD family'
J5276_07310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
J5276_07310	COG0321	lipoyl(octanoyl) transferase activity
J5276_07320	COG2226	methyltransferase
J5276_07330	COG0328	RNA-DNA hybrid ribonuclease activity
J5276_07335	COG1879	ABC-type sugar transport system periplasmic component
J5276_07340	COG1129	ABC transporter
J5276_07345	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_07350	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_07355	COG1609	Transcriptional regulator
J5276_07365	COG0673	inositol 2-dehydrogenase activity
J5276_07395	COG0784	Response regulator, receiver
J5276_07395	COG4191	Histidine kinase
J5276_07400	COG2202	Pas domain
J5276_07400	COG3920	Histidine kinase
J5276_07405	COG0784	Response regulator, receiver
J5276_07410	COG0784	Response regulator, receiver
J5276_07410	COG4191	Histidine kinase
J5276_07415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_07430	COG2828	Protein conserved in bacteria
J5276_07435	COG0583	DNA-binding transcription factor activity
J5276_07445	COG2801	Transposase and inactivated derivatives
J5276_07480	COG0625	glutathione transferase activity
J5276_07485	COG0450	alkyl hydroperoxide reductase
J5276_07495	COG1671	Belongs to the UPF0178 family
J5276_07505	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J5276_07510	COG0251	oxidation-reduction process
J5276_07515	COG1309	transcriptional regulator
J5276_07530	COG0546	phosphoglycolate phosphatase activity
J5276_07535	COG0564	pseudouridine synthase activity
J5276_07540	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J5276_07570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5276_07575	COG0509	glycine decarboxylation via glycine cleavage system
J5276_07580	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5276_07580	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
J5276_07620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5276_07620	COG1648	precorrin-2 dehydrogenase activity
J5276_07630	COG3956	TIGRFAM MazG family protein
J5276_07635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J5276_07640	COG1923	regulation of RNA biosynthetic process
J5276_07645	COG0569	domain protein
J5276_07650	COG2204	response regulator
J5276_07655	COG5000	phosphorelay sensor kinase activity
J5276_07660	COG2204	response regulator
J5276_07665	COG3852	Histidine kinase
J5276_07675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J5276_07675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J5276_07680	COG1546	Belongs to the CinA family
J5276_07685	COG2867	negative regulation of translational initiation
J5276_07705	COG0697	spore germination
J5276_07710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J5276_07720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J5276_07730	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5276_07735	COG0022	dehydrogenase e1 component
J5276_07735	COG0508	dehydrogenase complex catalyzes the overall conversion of
J5276_07740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J5276_07750	COG0148	phosphopyruvate hydratase activity
J5276_07755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J5276_07765	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J5276_07780	COG0582	viral genome integration into host DNA
J5276_07805	COG1802	Transcriptional regulator
J5276_07805	COG4626	Terminase
J5276_07850	COG0372	Belongs to the citrate synthase family
J5276_07855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5276_07860	COG3494	Protein of unknown function (DUF1009)
J5276_07865	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5276_07870	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5276_07875	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J5276_07880	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J5276_07885	COG0750	zinc metalloprotease
J5276_07895	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J5276_07900	COG0233	cytoplasmic translational termination
J5276_07905	COG0528	UMP kinase activity
J5276_07910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J5276_07915	COG0052	Belongs to the universal ribosomal protein uS2 family
J5276_07940	COG0537	adenosine 5'-monophosphoramidase activity
J5276_07975	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J5276_08005	COG3106	COG3106 Predicted ATPase
J5276_08010	COG3768	UPF0283 membrane protein
J5276_08020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J5276_08025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J5276_08030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J5276_08040	COG0633	Ferredoxin
J5276_08055	COG0384	phenazine biosynthesis protein PhzF
J5276_08060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J5276_08080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5276_08090	COG1530	ribonuclease E activity
J5276_08095	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_08115	COG0436	Aminotransferase
J5276_08125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5276_08130	COG0511	ligase activity, forming carbon-carbon bonds
J5276_08140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J5276_08155	COG0456	acetyltransferase
J5276_08165	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5276_08180	COG3811	Belongs to the UPF0386 family
J5276_08185	COG0154	amidase activity
J5276_08190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J5276_08195	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
J5276_08200	COG2824	Alkylphosphonate utilization operon protein PhnA
J5276_08205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J5276_08225	COG0456	acetyltransferase
J5276_08230	COG1960	acyl-CoA dehydrogenase activity
J5276_08235	COG0540	Belongs to the ATCase OTCase family
J5276_08245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J5276_08250	COG0758	DNA mediated transformation
J5276_08260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J5276_08265	COG0557	exoribonuclease II activity
J5276_08280	COG0477	Major facilitator Superfamily
J5276_08285	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J5276_08295	COG0784	Response regulator, receiver
J5276_08305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5276_08320	COG1136	(ABC) transporter
J5276_08330	COG0442	prolyl-tRNA aminoacylation
J5276_08345	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J5276_08345	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J5276_08350	COG1007	ATP synthesis coupled electron transport
J5276_08365	COG0713	ATP synthesis coupled electron transport
J5276_08375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_08380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J5276_08390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J5276_08395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
J5276_08405	COG0649	NAD binding
J5276_08415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_08420	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_08425	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J5276_08460	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J5276_08465	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J5276_08470	COG0740	serine-type endopeptidase activity
J5276_08475	COG2199	diguanylate cyclase activity
J5276_08495	COG1832	CoA-binding protein
J5276_08510	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J5276_08515	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J5276_08520	COG0010	Belongs to the arginase family
J5276_08525	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J5276_08535	COG1612	heme a metabolic process
J5276_08605	COG1528	Iron-storage protein
J5276_08615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J5276_08620	COG4139	cobalamin transport
J5276_08635	COG1238	metal cluster binding
J5276_08640	COG3932	Exopolysaccharide synthesis, ExoD
J5276_08685	COG1196	nuclear chromosome segregation
J5276_08770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5276_08780	COG0415	Belongs to the DNA photolyase family
J5276_08795	COG2897	thiosulfate sulfurtransferase activity
J5276_08820	COG0737	Belongs to the 5'-nucleotidase family
J5276_08830	COG0583	DNA-binding transcription factor activity
J5276_08835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J5276_08850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5276_08855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J5276_08865	COG0747	negative chemotaxis
J5276_08875	COG0444	Belongs to the ABC transporter superfamily
J5276_08880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_08885	COG0601	transmembrane transport
J5276_08920	COG0776	regulation of translation
J5276_08925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5276_08930	COG0416	fatty acid biosynthetic process
J5276_08950	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J5276_08955	COG2814	Major facilitator Superfamily
J5276_08960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J5276_08965	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J5276_08970	COG1280	lysine exporter protein (LysE YggA)
J5276_08980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5276_08980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J5276_08985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J5276_08990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5276_09010	COG0113	porphobilinogen synthase activity
J5276_09020	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J5276_09025	COG2336	PFAM SpoVT AbrB
J5276_09030	COG3654	unkown
J5276_09035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J5276_09045	COG0659	secondary active sulfate transmembrane transporter activity
J5276_09050	COG4452	Inner membrane protein CreD
J5276_09055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J5276_09060	COG0477	Major facilitator Superfamily
J5276_09065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J5276_09075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
J5276_09100	COG0248	Ppx GppA phosphatase
J5276_09105	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J5276_09115	COG0628	permease
J5276_09120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J5276_09125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J5276_09140	COG0243	molybdopterin cofactor binding
J5276_09145	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J5276_09160	COG0625	glutathione transferase activity
J5276_09170	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_09175	COG0322	excinuclease ABC activity
J5276_09180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J5276_09190	COG0314	molybdopterin synthase activity
J5276_09210	COG0105	UTP biosynthetic process
J5276_09220	COG3706	GGDEF domain
J5276_09225	COG0488	(ABC) transporter
J5276_09250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5276_09265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J5276_09275	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5276_09280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J5276_09290	COG0194	GDP metabolic process
J5276_09295	COG1561	YicC-like family, N-terminal region
J5276_09300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J5276_09305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5276_09310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_09320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J5276_09325	COG0667	Aldo Keto reductase
J5276_09330	COG0360	Binds together with S18 to 16S ribosomal RNA
J5276_09335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J5276_09345	COG0359	binds to the 23S rRNA
J5276_09370	COG0305	Participates in initiation and elongation during chromosome replication
J5276_09380	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J5276_09390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5276_09405	COG1286	toxin biosynthetic process
J5276_09410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J5276_09415	COG4221	oxidoreductase activity
J5276_09420	COG0215	cysteine-tRNA ligase activity
J5276_09425	COG2852	Protein conserved in bacteria
J5276_09470	COG5265	(ABC) transporter
J5276_09475	COG0688	phosphatidylethanolamine metabolic process
J5276_09480	COG1183	phosphatidylcholine synthase activity
J5276_09495	COG1742	UPF0060 membrane protein
J5276_09520	COG0354	folic acid binding
J5276_09525	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
J5276_09535	COG0668	transmembrane transport
J5276_09540	COG3443	Belongs to the bacterial solute-binding protein 9 family
J5276_09545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_09560	COG0346	lactoylglutathione lyase activity
J5276_09570	COG1418	mRNA catabolic process
J5276_09580	COG2226	methyltransferase
J5276_09590	COG1381	Involved in DNA repair and RecF pathway recombination
J5276_09595	COG0784	Response regulator, receiver
J5276_09600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J5276_09605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J5276_09610	COG0571	ribonuclease III activity
J5276_09615	COG0681	Belongs to the peptidase S26 family
J5276_09620	COG0736	holo-[acyl-carrier-protein] synthase activity
J5276_09640	COG1758	RNA polymerase activity
J5276_09650	COG0840	transmembrane signaling receptor activity
J5276_09655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J5276_09660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_09665	COG0741	lytic transglycosylase activity
J5276_09690	COG0582	viral genome integration into host DNA
J5276_09760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5276_09790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J5276_09820	COG2814	Major facilitator Superfamily
J5276_09825	COG2239	Acts as a magnesium transporter
J5276_09830	COG1968	undecaprenyl-diphosphatase activity
J5276_09835	COG1733	regulation of RNA biosynthetic process
J5276_09840	COG0604	alcohol dehydrogenase
J5276_09865	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_09875	COG0443	Heat shock 70 kDa protein
J5276_09895	COG0308	aminopeptidase N
J5276_09905	COG2205	protein histidine kinase activity
J5276_09905	COG2202	Pas domain
J5276_09910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J5276_09920	COG3011	Protein conserved in bacteria
J5276_09930	COG0745	RESPONSE REGULATOR receiver
J5276_09935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J5276_09940	COG3088	subunit of a heme lyase
J5276_09945	COG1138	Cytochrome C-type biogenesis protein
J5276_09950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
J5276_09955	COG4235	cytochrome complex assembly
J5276_10060	COG4695	Portal protein
J5276_10110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J5276_10115	COG3920	Histidine kinase
J5276_10115	COG2202	Pas domain
J5276_10120	COG1621	beta-fructofuranosidase activity
J5276_10155	COG2983	Belongs to the UPF0260 family
J5276_10160	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5276_10215	COG2205	protein histidine kinase activity
J5276_10225	COG2166	iron-sulfur cluster assembly
J5276_10240	COG4957	zinc ion binding
J5276_10245	COG1320	monovalent cation:proton antiporter activity
J5276_10250	COG2212	antiporter activity
J5276_10255	COG1863	multisubunit Na H antiporter MnhE subunit
J5276_10260	COG0651	ATP synthesis coupled electron transport
J5276_10265	COG1006	Multisubunit Na H antiporter MnhC subunit
J5276_10270	COG2111	Na H antiporter
J5276_10275	COG2111	Na H antiporter
J5276_10275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5276_10280	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5276_10285	COG1280	lysine exporter protein (LysE YggA)
J5276_10295	COG1272	protein, Hemolysin III
J5276_10310	COG2514	catechol 2,3-dioxygenase activity
J5276_10320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5276_10320	COG2169	Transcriptional regulator
J5276_10330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_10350	COG4176	ABC-type proline glycine betaine transport system permease component
J5276_10380	COG0789	Transcriptional regulator
J5276_10410	COG2010	Cytochrome c
J5276_10415	COG3909	cytochrome
J5276_10435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J5276_10450	COG0583	DNA-binding transcription factor activity
J5276_10455	COG0840	transmembrane signaling receptor activity
J5276_10460	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5276_10465	COG4106	trans-aconitate 2-methyltransferase activity
J5276_10475	COG2378	regulation of single-species biofilm formation
J5276_10480	COG0656	L-ascorbic acid biosynthetic process
J5276_10485	COG1280	lysine exporter protein (LysE YggA)
J5276_10495	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J5276_10500	COG1733	regulation of RNA biosynthetic process
J5276_10510	COG0433	COG0433 Predicted ATPase
J5276_10520	COG4221	oxidoreductase activity
J5276_10525	COG0583	DNA-binding transcription factor activity
J5276_10560	COG0488	(ABC) transporter
J5276_10575	COG1764	response to oxidative stress
J5276_10580	COG1846	Transcriptional regulator
J5276_10595	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_10600	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_10615	COG1793	dna ligase
J5276_10615	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
J5276_10625	COG0477	Major facilitator Superfamily
J5276_10670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J5276_10675	COG1012	belongs to the aldehyde dehydrogenase family
J5276_10680	COG1309	transcriptional regulator
J5276_10690	COG2203	Gaf domain
J5276_10690	COG2200	EAL domain
J5276_10690	COG2199	diguanylate cyclase activity
J5276_10700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5276_10705	COG4208	sulfate ABC transporter
J5276_10710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5276_10715	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J5276_10720	COG1959	2 iron, 2 sulfur cluster binding
J5276_10725	COG0175	sulfate reduction
J5276_10730	COG0175	sulfate reduction
J5276_10735	COG2895	sulfate adenylyltransferase (ATP) activity
J5276_10765	COG0579	oxidoreductase
J5276_10785	COG1823	symporter activity
J5276_10800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J5276_10800	COG0574	Belongs to the PEP-utilizing enzyme family
J5276_10805	COG2514	catechol 2,3-dioxygenase activity
J5276_10810	COG1196	nuclear chromosome segregation
J5276_10815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J5276_10835	COG2189	Belongs to the N(4) N(6)-methyltransferase family
J5276_10855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5276_10870	COG0612	Peptidase, M16
J5276_10875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5276_10895	COG1678	Uncharacterized ACR, COG1678
J5276_10905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J5276_10905	COG0678	peroxiredoxin activity
J5276_10915	COG0328	RNA-DNA hybrid ribonuclease activity
J5276_10920	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J5276_10925	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J5276_10930	COG3346	SURF1 family
J5276_10945	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
J5276_10950	COG0109	protoheme IX farnesyltransferase activity
J5276_10955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5276_10970	COG0312	modulator of DNA gyrase
J5276_10980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5276_10995	COG0259	pyridoxamine-phosphate oxidase activity
J5276_11010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J5276_11030	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J5276_11035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_11035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_11040	COG3214	Protein conserved in bacteria
J5276_11045	COG1122	ATPase activity
J5276_11050	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J5276_11055	COG1268	BioY protein
J5276_11060	COG0123	including yeast histone deacetylase and acetoin utilization protein
J5276_11065	COG1722	exodeoxyribonuclease VII activity
J5276_11070	COG1741	Belongs to the pirin family
J5276_11075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J5276_11100	COG0840	transmembrane signaling receptor activity
J5276_11105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
J5276_11110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J5276_11125	COG1960	acyl-CoA dehydrogenase activity
J5276_11150	COG4638	Rieske (2fe-2S)
J5276_11160	COG0009	L-threonylcarbamoyladenylate synthase
J5276_11180	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J5276_11190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5276_11195	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J5276_11205	COG0356	it plays a direct role in the translocation of protons across the membrane
J5276_11220	COG3158	transport of potassium into the cell
J5276_11225	COG0598	Magnesium transport protein CorA
J5276_11240	COG2197	response regulator
J5276_11250	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_11255	COG3734	2-keto-3-deoxy-galactonokinase
J5276_11260	COG0800	Aldolase
J5276_11265	COG3386	PFAM SMP-30 Gluconolaconase
J5276_11270	COG5001	Diguanylate cyclase
J5276_11270	COG3300	MHYT domain
J5276_11275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_11275	COG2205	protein histidine kinase activity
J5276_11280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J5276_11290	COG1663	tetraacyldisaccharide 4'-kinase activity
J5276_11300	COG1519	Transferase
J5276_11315	COG0312	modulator of DNA gyrase
J5276_11325	COG1752	Esterase of the alpha-beta hydrolase superfamily
J5276_11330	COG0742	ribosomal rna small subunit methyltransferase
J5276_11335	COG1187	pseudouridine synthase activity
J5276_11340	COG0590	tRNA wobble adenosine to inosine editing
J5276_11350	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J5276_11355	COG0196	riboflavin kinase activity
J5276_11365	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5276_11370	COG0459	protein refolding
J5276_11380	COG2259	Doxx family
J5276_11385	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J5276_11390	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J5276_11400	COG0124	histidyl-tRNA synthetase
J5276_11420	COG0583	DNA-binding transcription factor activity
J5276_11425	COG2855	membrane
J5276_11435	COG2818	Glycosylase
J5276_11440	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_11450	COG0247	lactate metabolic process
J5276_11455	COG0277	FAD linked oxidase domain protein
J5276_11460	COG0277	FAD linked oxidase domain protein
J5276_11465	COG0583	DNA-binding transcription factor activity
J5276_11475	COG2186	Transcriptional regulator
J5276_11480	COG0438	transferase activity, transferring glycosyl groups
J5276_11485	COG0561	phosphatase activity
J5276_11495	COG0306	phosphate transporter
J5276_11515	COG0583	DNA-binding transcription factor activity
J5276_11540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5276_11545	COG2183	response to ionizing radiation
J5276_11550	COG0151	Belongs to the GarS family
J5276_11560	COG0840	transmembrane signaling receptor activity
J5276_11580	COG0751	glycine-tRNA ligase activity
J5276_11590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J5276_11595	COG1704	LemA family
J5276_11600	COG0752	glycyl-tRNA synthetase alpha subunit
J5276_11625	COG0142	geranyltranstransferase activity
J5276_11635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J5276_11640	COG0521	Mo-molybdopterin cofactor biosynthetic process
J5276_11670	COG0477	Major facilitator Superfamily
J5276_11675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J5276_11680	COG0248	Ppx GppA phosphatase
J5276_11690	COG2205	protein histidine kinase activity
J5276_11700	COG1177	transmembrane transport
J5276_11705	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_11710	COG3842	ATPase activity
J5276_11725	COG2224	Isocitrate lyase
J5276_11745	COG2081	HI0933 family
J5276_11755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_11765	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J5276_11770	COG0363	glucosamine-6-phosphate deaminase activity
J5276_11775	COG0129	dihydroxy-acid dehydratase activity
J5276_11790	COG3842	ATPase activity
J5276_11795	COG0366	Alpha amylase catalytic
J5276_11800	COG0395	ABC-type sugar transport system, permease component
J5276_11805	COG1175	transmembrane transport
J5276_11810	COG1653	transport
J5276_11815	COG1609	Transcriptional regulator
J5276_11820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J5276_11860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5276_11870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
J5276_11875	COG5443	negative regulation of bacterial-type flagellum assembly
J5276_11895	COG1749	Flagellar hook protein flgE
J5276_11920	COG1360	Flagellar Motor Protein
J5276_11940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
J5276_11945	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5276_11950	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5276_11955	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
J5276_11960	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
J5276_11970	COG4786	Flagellar basal body rod
J5276_11975	COG1157	protein secretion by the type III secretion system
J5276_11985	COG1815	bacterial-type flagellum-dependent cell motility
J5276_11990	COG1558	bacterial-type flagellum-dependent cell motility
J5276_11995	COG1677	Flagellar hook-basal body complex protein FliE
J5276_12000	COG4786	Flagellar basal body rod
J5276_12005	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
J5276_12010	COG1706	bacterial-type flagellum-dependent cell motility
J5276_12020	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
J5276_12030	COG1338	Plays a role in the flagellum-specific transport system
J5276_12045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5276_12060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J5276_12070	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J5276_12075	COG5328	Belongs to the UPF0262 family
J5276_12085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J5276_12090	COG0424	maF-like protein
J5276_12095	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J5276_12110	COG0436	Aminotransferase
J5276_12115	COG1970	mechanosensitive ion channel activity
J5276_12165	COG2801	Transposase and inactivated derivatives
J5276_12265	COG4373	Mu-like prophage FluMu protein gp28
J5276_12270	COG4383	Mu-like prophage protein gp29
J5276_12295	COG4397	Mu-like prophage major head subunit gpT
J5276_12365	COG3299	homolog of phage Mu protein gp47
J5276_12405	COG0840	transmembrane signaling receptor activity
J5276_12405	COG2972	Histidine kinase
J5276_12415	COG2771	luxR family
J5276_12420	COG1766	The M ring may be actively involved in energy transduction
J5276_12430	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
J5276_12435	COG0745	RESPONSE REGULATOR receiver
J5276_12440	COG2201	protein-glutamate methylesterase activity
J5276_12445	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
J5276_12450	COG2198	Histidine kinase
J5276_12450	COG0643	Histidine kinase
J5276_12455	COG0745	RESPONSE REGULATOR receiver
J5276_12465	COG0840	transmembrane signaling receptor activity
J5276_12475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J5276_12475	COG2111	Na H antiporter
J5276_12480	COG1006	Multisubunit Na H antiporter MnhC subunit
J5276_12485	COG0651	ATP synthesis coupled electron transport
J5276_12490	COG1863	multisubunit Na H antiporter MnhE subunit
J5276_12495	COG2212	antiporter activity
J5276_12500	COG1320	monovalent cation:proton antiporter activity
J5276_12515	COG1024	Enoyl-CoA hydratase
J5276_12515	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5276_12520	COG0183	Belongs to the thiolase family
J5276_12525	COG1960	acyl-CoA dehydrogenase activity
J5276_12555	COG1201	RNA secondary structure unwinding
J5276_12560	COG1959	2 iron, 2 sulfur cluster binding
J5276_12565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5276_12580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5276_12595	COG0167	dihydroorotate dehydrogenase activity
J5276_12645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J5276_12655	COG0717	Belongs to the dCTP deaminase family
J5276_12665	COG2967	ApaG domain
J5276_12675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5276_12680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J5276_12690	COG0745	RESPONSE REGULATOR receiver
J5276_12695	COG0704	Plays a role in the regulation of phosphate uptake
J5276_12700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J5276_12710	COG0573	inorganic phosphate transmembrane transporter activity
J5276_12715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J5276_12720	COG5002	protein histidine kinase activity
J5276_12725	COG2326	polyphosphate kinase activity
J5276_12765	COG4774	siderophore transport
J5276_12770	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J5276_12775	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_12780	COG3842	ATPase activity
J5276_12785	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_12790	COG0166	Belongs to the GPI family
J5276_12795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J5276_12815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J5276_12820	COG0418	dihydroorotase activity
J5276_12825	COG3938	Belongs to the proline racemase family
J5276_12835	COG0427	acetyl-CoA hydrolase
J5276_12850	COG0395	ABC-type sugar transport system, permease component
J5276_12855	COG1175	transmembrane transport
J5276_12860	COG3842	ATPase activity
J5276_12865	COG2226	methyltransferase
J5276_12880	COG0840	transmembrane signaling receptor activity
J5276_12885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J5276_12890	COG0594	ribonuclease P activity
J5276_12895	COG0706	membrane insertase activity
J5276_12900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J5276_12910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J5276_12935	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_12945	COG0840	transmembrane signaling receptor activity
J5276_12955	COG2171	N-acyltransferase activity
J5276_12960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_12970	COG0101	tRNA pseudouridine synthase activity
J5276_12975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J5276_12980	COG0242	peptide deformylase activity
J5276_12990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_12995	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J5276_13000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J5276_13005	COG1396	sequence-specific DNA binding
J5276_13010	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J5276_13020	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J5276_13025	COG1702	phosphate starvation-inducible protein PhoH
J5276_13030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J5276_13045	COG0456	acetyltransferase
J5276_13045	COG1214	PFAM Peptidase M22, glycoprotease
J5276_13050	COG1214	PFAM Peptidase M22, glycoprotease
J5276_13055	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
J5276_13065	COG0180	Tryptophanyl-tRNA synthetase
J5276_13075	COG0728	peptidoglycan biosynthetic process
J5276_13080	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J5276_13085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J5276_13100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J5276_13105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J5276_13120	COG0776	regulation of translation
J5276_13125	COG0616	signal peptide processing
J5276_13135	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J5276_13140	COG1137	ATPase activity
J5276_13150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J5276_13155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5276_13160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J5276_13165	COG1420	regulation of RNA biosynthetic process
J5276_13170	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J5276_13175	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J5276_13180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J5276_13185	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J5276_13190	COG0268	Binds directly to 16S ribosomal RNA
J5276_13195	COG1024	Enoyl-CoA hydratase
J5276_13200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J5276_13205	COG2226	methyltransferase
J5276_13210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J5276_13225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J5276_13230	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J5276_13235	COG0756	dUTP diphosphatase activity
J5276_13240	COG1280	lysine exporter protein (LysE YggA)
J5276_13245	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J5276_13255	COG0189	ligase activity
J5276_13265	COG3842	ATPase activity
J5276_13270	COG0395	ABC-type sugar transport system, permease component
J5276_13275	COG1175	transmembrane transport
J5276_13290	COG0792	nuclease activity
J5276_13295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
J5276_13305	COG3963	phosphatidate phosphatase activity
J5276_13315	COG0284	orotidine-5'-phosphate decarboxylase activity
J5276_13330	COG1968	undecaprenyl-diphosphatase activity
J5276_13340	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J5276_13350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J5276_13380	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
J5276_13395	COG0519	Catalyzes the synthesis of GMP from XMP
J5276_13395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J5276_13415	COG0477	Major facilitator Superfamily
J5276_13480	COG0583	DNA-binding transcription factor activity
J5276_13490	COG2948	multi-organism process
J5276_13505	COG3846	protein secretion by the type IV secretion system
J5276_13520	COG3451	type IV secretory pathway VirB4
J5276_13535	COG4962	Type ii secretion system protein e
J5276_13560	COG0741	lytic transglycosylase activity
J5276_13585	COG1192	Involved in chromosome partitioning
J5276_13615	COG5489	Protein of unknown function (DUF736)
J5276_13730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J5276_13765	COG1393	Belongs to the ArsC family
J5276_13775	COG2309	aminopeptidase activity
J5276_13780	COG0697	spore germination
J5276_13785	COG1846	Transcriptional regulator
J5276_13795	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_13800	COG1570	exodeoxyribonuclease VII activity
J5276_13825	COG4977	sequence-specific DNA binding
J5276_13845	COG0667	Aldo Keto reductase
J5276_13850	COG0072	phenylalanine-tRNA ligase activity
J5276_13850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J5276_13855	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J5276_13865	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J5276_13870	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J5276_13875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J5276_13900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5276_13905	COG2169	Transcriptional regulator
J5276_13905	COG1917	Cupin 2, conserved barrel domain protein
J5276_13935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5276_13940	COG0481	GTPase activity
J5276_13970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_13975	COG0697	spore germination
J5276_13980	COG3757	hydrolase, family 25
J5276_13985	COG3422	double-strand break repair
J5276_13990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5276_14030	COG4964	Belongs to the GSP D family
J5276_14065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J5276_14070	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
J5276_14080	COG0791	NLP P60 protein
J5276_14095	COG0697	spore germination
J5276_14115	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_14120	COG1959	2 iron, 2 sulfur cluster binding
J5276_14130	COG1732	Glycine betaine
J5276_14135	COG1174	glycine betaine transport
J5276_14140	COG1125	glycine betaine transport
J5276_14145	COG1174	glycine betaine transport
J5276_14150	COG3265	gluconokinase activity
J5276_14155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_14160	COG0174	glutamine synthetase
J5276_14165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_14170	COG4172	Belongs to the ABC transporter superfamily
J5276_14175	COG4239	(ABC) transporter, permease
J5276_14180	COG4174	ABC transporter (Permease)
J5276_14185	COG4166	transmembrane transport
J5276_14190	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
J5276_14195	COG1803	Methylglyoxal synthase
J5276_14200	COG0837	glucose binding
J5276_14205	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J5276_14210	COG2188	Transcriptional regulator
J5276_14215	COG3624	Phosphonate C-P lyase system protein PhnG
J5276_14220	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
J5276_14225	COG3626	phosphonate metabolism
J5276_14230	COG3627	carbon phosphorus lyase activity
J5276_14235	COG4107	phosphonate C-P lyase system protein PhnK
J5276_14240	COG4778	phosphonate C-P lyase system protein PhnL
J5276_14250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
J5276_14260	COG3639	organic phosphonate transmembrane transporter activity
J5276_14265	COG3639	organic phosphonate transmembrane transporter activity
J5276_14270	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J5276_14275	COG3454	Phosphonate metabolism
J5276_14280	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
J5276_14295	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_14305	COG0848	biopolymer transport protein
J5276_14325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_14360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J5276_14370	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
J5276_14385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J5276_14390	COG0067	glutamate synthase
J5276_14390	COG0069	glutamate synthase activity
J5276_14390	COG0070	glutamate synthase
J5276_14395	COG0477	Major facilitator Superfamily
J5276_14400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J5276_14405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J5276_14410	COG1845	cytochrome c oxidase, subunit III
J5276_14415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J5276_14425	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
J5276_14430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J5276_14435	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J5276_14445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
J5276_14450	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J5276_14460	COG0295	cytidine deaminase activity
J5276_14465	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5276_14470	COG1079	Belongs to the binding-protein-dependent transport system permease family
J5276_14475	COG3845	ABC transporter
J5276_14480	COG1744	ABC transporter substrate-binding protein PnrA-like
J5276_14485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J5276_14500	COG0443	Heat shock 70 kDa protein
J5276_14505	COG0484	heat shock protein binding
J5276_14515	COG2900	Belongs to the SlyX family
J5276_14545	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J5276_14555	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5276_14555	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J5276_14565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_14570	COG1278	Cold shock
J5276_14575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J5276_14580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
J5276_14590	COG3474	cytochrome
J5276_14595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J5276_14600	COG0077	Prephenate dehydratase
J5276_14600	COG1605	Chorismate mutase
J5276_14605	COG2816	NAD+ diphosphatase activity
J5276_14620	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J5276_14625	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
J5276_14635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J5276_14640	COG2951	lytic endotransglycosylase activity
J5276_14645	COG2814	Major facilitator Superfamily
J5276_14650	COG0779	Required for maturation of 30S ribosomal subunits
J5276_14665	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J5276_14665	COG3064	Membrane
J5276_14670	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J5276_14675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J5276_14680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J5276_14685	COG1185	polyribonucleotide nucleotidyltransferase activity
J5276_14700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_14725	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J5276_14745	COG1780	Probably involved in ribonucleotide reductase function
J5276_14755	COG1072	(Pantothenic acid kinase))
J5276_14780	COG0514	ATP-dependent DNA helicase (RecQ)
J5276_14815	COG1643	Atp-dependent helicase
J5276_14825	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
J5276_14840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J5276_14850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J5276_14855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J5276_14860	COG0131	Imidazoleglycerol-phosphate dehydratase
J5276_14870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J5276_14875	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J5276_14880	COG0107	imidazoleglycerol-phosphate synthase activity
J5276_14885	COG0140	phosphoribosyl-ATP diphosphatase activity
J5276_14890	COG1072	(Pantothenic acid kinase))
J5276_14895	COG1652	LysM domain
J5276_14905	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
J5276_14910	COG0745	RESPONSE REGULATOR receiver
J5276_14915	COG0642	Histidine kinase
J5276_14920	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
J5276_14925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5276_14925	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J5276_14930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J5276_14935	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J5276_14940	COG2205	protein histidine kinase activity
J5276_14945	COG0802	atpase or kinase
J5276_14950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5276_14960	COG1074	ATP-dependent DNA helicase activity
J5276_14970	COG0285	dihydrofolate synthase activity
J5276_14975	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
J5276_14980	COG0159	tryptophan synthase activity
J5276_14985	COG0133	tryptophan synthase activity
J5276_14990	COG0135	phosphoribosylanthranilate isomerase activity
J5276_15005	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_15030	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J5276_15040	COG3030	protein affecting phage T7 exclusion by the F plasmid
J5276_15045	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J5276_15055	COG0237	dephospho-CoA kinase activity
J5276_15060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5276_15065	COG0424	maF-like protein
J5276_15070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J5276_15075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J5276_15080	COG1981	membrane
J5276_15085	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
J5276_15090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J5276_15095	COG0445	tRNA wobble uridine modification
J5276_15100	COG0357	Ribosomal RNA small subunit methyltransferase G
J5276_15155	COG3547	Transposase (IS116 IS110 IS902 family)
J5276_15205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J5276_15210	COG0358	DNA primase activity
J5276_15275	COG2814	Major facilitator Superfamily
J5276_15305	COG0596	Alpha beta hydrolase
J5276_15330	COG1764	response to oxidative stress
J5276_15340	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
J5276_15350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_15375	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_15395	COG1522	sequence-specific DNA binding
J5276_15405	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_15420	COG0438	transferase activity, transferring glycosyl groups
J5276_15440	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J5276_15475	COG2197	response regulator
J5276_15480	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J5276_15485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5276_15490	COG4310	Domain of unknown function (DUF2172)
J5276_15495	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J5276_15505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J5276_15510	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J5276_15515	COG2197	response regulator
J5276_15540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_15580	COG4178	(ABC) transporter
J5276_15600	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J5276_15610	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5276_15620	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5276_15635	COG1177	transmembrane transport
J5276_15640	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_15645	COG3842	ATPase activity
J5276_15675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_15680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_15685	COG0601	transmembrane transport
J5276_15690	COG0747	negative chemotaxis
J5276_15720	COG1522	sequence-specific DNA binding
J5276_15735	COG0477	Major facilitator Superfamily
J5276_15740	COG0583	DNA-binding transcription factor activity
J5276_15755	COG0583	DNA-binding transcription factor activity
J5276_15765	COG0747	negative chemotaxis
J5276_15770	COG0601	transmembrane transport
J5276_15775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_15790	COG1278	Cold shock
J5276_15810	COG0784	Response regulator, receiver
J5276_15810	COG5002	protein histidine kinase activity
J5276_15810	COG2198	Histidine kinase
J5276_15820	COG0405	Gamma-glutamyltransferase
J5276_15825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_15830	COG0601	transmembrane transport
J5276_15835	COG0747	negative chemotaxis
J5276_15840	COG2186	Transcriptional regulator
J5276_15880	COG1595	DNA-templated transcription, initiation
J5276_15890	COG0395	ABC-type sugar transport system, permease component
J5276_15895	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_15905	COG3842	ATPase activity
J5276_15915	COG0765	amino acid transport
J5276_15920	COG0765	amino acid transport
J5276_15925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_15930	COG2186	Transcriptional regulator
J5276_15945	COG1063	alcohol dehydrogenase
J5276_15950	COG3284	Transcriptional regulator
J5276_15980	COG1653	transport
J5276_15985	COG1175	transmembrane transport
J5276_15990	COG0395	ABC-type sugar transport system, permease component
J5276_15995	COG3842	ATPase activity
J5276_16005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_16010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_16015	COG1116	anion transmembrane transporter activity
J5276_16020	COG0395	ABC-type sugar transport system, permease component
J5276_16025	COG1175	transmembrane transport
J5276_16055	COG1609	Transcriptional regulator
J5276_16070	COG1082	Xylose isomerase domain protein TIM barrel
J5276_16075	COG3842	ATPase activity
J5276_16080	COG0395	ABC-type sugar transport system, permease component
J5276_16085	COG1175	transmembrane transport
J5276_16090	COG1653	transport
J5276_16095	COG1309	transcriptional regulator
J5276_16100	COG0673	inositol 2-dehydrogenase activity
J5276_16115	COG0673	inositol 2-dehydrogenase activity
J5276_16120	COG1278	Cold shock
J5276_16130	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5276_16165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J5276_16170	COG0577	efflux transmembrane transporter activity
J5276_16170	COG1136	(ABC) transporter
J5276_16175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_16195	COG2205	protein histidine kinase activity
J5276_16200	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J5276_16215	COG3842	ATPase activity
J5276_16220	COG0395	ABC-type sugar transport system, permease component
J5276_16225	COG1175	transmembrane transport
J5276_16245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_16250	COG3618	amidohydrolase
J5276_16255	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_16260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_16265	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_16270	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
J5276_16275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_16280	COG2186	Transcriptional regulator
J5276_16295	COG0667	Aldo Keto reductase
J5276_16325	COG4977	sequence-specific DNA binding
J5276_16330	COG2223	nitrite transmembrane transporter activity
J5276_16335	COG0583	DNA-binding transcription factor activity
J5276_16340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_16350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_16355	COG2084	Dehydrogenase
J5276_16370	COG1609	Transcriptional regulator
J5276_16375	COG1063	alcohol dehydrogenase
J5276_16380	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_16390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_16395	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
J5276_16400	COG1175	transmembrane transport
J5276_16405	COG0395	ABC-type sugar transport system, permease component
J5276_16420	COG0395	ABC-type sugar transport system, permease component
J5276_16430	COG2182	Extracellular solute-binding protein
J5276_16435	COG0626	cystathionine gamma-synthase activity
J5276_16445	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5276_16455	COG1121	(ABC) transporter
J5276_16460	COG0523	cobalamin synthesis protein
J5276_16475	COG0523	cobalamin synthesis protein
J5276_16480	COG1653	transport
J5276_16485	COG1175	transmembrane transport
J5276_16490	COG0395	ABC-type sugar transport system, permease component
J5276_16495	COG3842	ATPase activity
J5276_16505	COG3047	cAMP biosynthetic process
J5276_16530	COG0583	DNA-binding transcription factor activity
J5276_16535	COG1879	ABC-type sugar transport system periplasmic component
J5276_16540	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_16545	COG1129	ABC transporter
J5276_16550	COG3447	MASE1 domain protein
J5276_16550	COG5002	protein histidine kinase activity
J5276_16550	COG5001	Diguanylate cyclase
J5276_16555	COG3257	ureidoglycine aminohydrolase activity
J5276_16565	COG5001	Diguanylate cyclase
J5276_16570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_16580	COG0747	negative chemotaxis
J5276_16585	COG0601	transmembrane transport
J5276_16590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_16600	COG4608	Belongs to the ABC transporter superfamily
J5276_16605	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J5276_16615	COG0129	dihydroxy-acid dehydratase activity
J5276_16620	COG1879	ABC-type sugar transport system periplasmic component
J5276_16625	COG1129	ABC transporter
J5276_16630	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_16635	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_16640	COG2186	Transcriptional regulator
J5276_16655	COG0587	DNA-directed DNA polymerase activity
J5276_16685	COG0673	inositol 2-dehydrogenase activity
J5276_16695	COG3842	ATPase activity
J5276_16700	COG0395	ABC-type sugar transport system, permease component
J5276_16705	COG1175	transmembrane transport
J5276_16710	COG1653	transport
J5276_16720	COG0673	inositol 2-dehydrogenase activity
J5276_16735	COG5001	Diguanylate cyclase
J5276_16750	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J5276_16755	COG2894	cell division
J5276_16760	COG0850	regulation of cytokinetic process
J5276_16765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J5276_16770	COG2186	Transcriptional regulator
J5276_16775	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_16785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_16790	COG1063	alcohol dehydrogenase
J5276_16795	COG1312	Catalyzes the dehydration of D-mannonate
J5276_16810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J5276_16815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_16815	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5276_16820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_16835	COG0625	glutathione transferase activity
J5276_16840	COG4172	Belongs to the ABC transporter superfamily
J5276_16845	COG1921	L-seryl-tRNASec selenium transferase activity
J5276_16860	COG3964	amidohydrolase
J5276_16870	COG0601	transmembrane transport
J5276_16875	COG0747	negative chemotaxis
J5276_16885	COG0438	transferase activity, transferring glycosyl groups
J5276_16930	COG4989	oxidoreductase activity
J5276_16940	COG2188	Transcriptional regulator
J5276_16945	COG3842	ATPase activity
J5276_16950	COG1653	transport
J5276_16955	COG1175	transmembrane transport
J5276_16960	COG0395	ABC-type sugar transport system, permease component
J5276_16965	COG1501	Belongs to the glycosyl hydrolase 31 family
J5276_16975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_16980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_16985	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J5276_16990	COG0352	thiamine-phosphate diphosphorylase activity
J5276_16995	COG0351	phosphomethylpyrimidine kinase
J5276_17000	COG1522	sequence-specific DNA binding
J5276_17005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5276_17010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_17025	COG2204	response regulator
J5276_17030	COG4191	Histidine kinase
J5276_17035	COG1301	dicarboxylic acid transport
J5276_17045	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_17050	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_17060	COG1473	amidohydrolase
J5276_17080	COG1215	transferase activity, transferring glycosyl groups
J5276_17090	COG2942	2-epimerase
J5276_17115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_17155	COG3307	-O-antigen
J5276_17160	COG1596	polysaccharide export
J5276_17165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J5276_17180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_17185	COG0840	transmembrane signaling receptor activity
J5276_17190	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_17200	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_17210	COG2094	Belongs to the DNA glycosylase MPG family
J5276_17225	COG1609	Transcriptional regulator
J5276_17230	COG1653	transport
J5276_17245	COG3842	ATPase activity
J5276_17255	COG0673	inositol 2-dehydrogenase activity
J5276_17260	COG0602	queuosine metabolic process
J5276_17265	COG0720	synthase
J5276_17270	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J5276_17280	COG0673	inositol 2-dehydrogenase activity
J5276_17295	COG0395	ABC-type sugar transport system, permease component
J5276_17300	COG1175	transmembrane transport
J5276_17325	COG0583	DNA-binding transcription factor activity
J5276_17330	COG0280	phosphate acetyltransferase
J5276_17330	COG0281	malic enzyme
J5276_17345	COG0765	amino acid transport
J5276_17350	COG1126	abc transporter atp-binding protein
J5276_17355	COG2079	MmgE PrpD family protein
J5276_17360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_17385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
J5276_17395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5276_17400	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J5276_17405	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_17410	COG1129	ABC transporter
J5276_17420	COG1473	amidohydrolase
J5276_17425	COG0747	negative chemotaxis
J5276_17435	COG4172	Belongs to the ABC transporter superfamily
J5276_17440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_17445	COG0601	transmembrane transport
J5276_17450	COG0583	DNA-binding transcription factor activity
J5276_17455	COG1446	asparaginase
J5276_17470	COG0747	negative chemotaxis
J5276_17490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_17495	COG0601	transmembrane transport
J5276_17500	COG2197	response regulator
J5276_17505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_17510	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
J5276_17530	COG1595	DNA-templated transcription, initiation
J5276_17535	COG1120	ATPase activity
J5276_17540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_17555	COG2226	methyltransferase
J5276_17565	COG1120	ATPase activity
J5276_17570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_17590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5276_17605	COG1012	belongs to the aldehyde dehydrogenase family
J5276_17610	COG0473	3-isopropylmalate dehydrogenase activity
J5276_17615	COG1012	belongs to the aldehyde dehydrogenase family
J5276_17620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_17650	COG0601	transmembrane transport
J5276_17655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_17660	COG4172	Belongs to the ABC transporter superfamily
J5276_17665	COG1522	sequence-specific DNA binding
J5276_17680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_17685	COG1126	abc transporter atp-binding protein
J5276_17695	COG1473	amidohydrolase
J5276_17700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17710	COG1959	2 iron, 2 sulfur cluster binding
J5276_17720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_17725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17745	COG1960	acyl-CoA dehydrogenase activity
J5276_17755	COG0747	negative chemotaxis
J5276_17770	COG0444	Belongs to the ABC transporter superfamily
J5276_17780	COG0667	Aldo Keto reductase
J5276_17790	COG0583	DNA-binding transcription factor activity
J5276_17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17810	COG0747	negative chemotaxis
J5276_17815	COG1473	amidohydrolase
J5276_17820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_17860	COG4608	Belongs to the ABC transporter superfamily
J5276_17865	COG0444	Belongs to the ABC transporter superfamily
J5276_17875	COG0601	transmembrane transport
J5276_17885	COG2186	Transcriptional regulator
J5276_17900	COG0300	oxidoreductase activity
J5276_17910	COG3453	Protein conserved in bacteria
J5276_17910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_17915	COG0640	Transcriptional regulator
J5276_17925	COG2391	methyltransferase activity
J5276_17930	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J5276_17940	COG0022	dehydrogenase e1 component
J5276_17950	COG1960	acyl-CoA dehydrogenase activity
J5276_17955	COG0183	Belongs to the thiolase family
J5276_17965	COG1960	acyl-CoA dehydrogenase activity
J5276_17970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5276_17985	COG1024	Enoyl-CoA hydratase
J5276_17990	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J5276_17995	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J5276_18000	COG4952	isomerase
J5276_18005	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_18005	COG3347	Dehydrogenase
J5276_18010	COG1349	DNA-binding transcription factor activity
J5276_18020	COG1129	ABC transporter
J5276_18025	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_18030	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_18035	COG3254	rhamnose metabolic process
J5276_18050	COG2264	protein methyltransferase activity
J5276_18055	COG5001	Diguanylate cyclase
J5276_18070	COG4335	DNA alkylation repair
J5276_18075	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J5276_18080	COG4208	sulfate ABC transporter
J5276_18090	COG4150	thiosulfate binding
J5276_18095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J5276_18110	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J5276_18120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5276_18130	COG1040	competence protein
J5276_18135	COG2226	methyltransferase
J5276_18150	COG0494	nUDIX hydrolase
J5276_18160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J5276_18165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J5276_18170	COG0653	protein targeting
J5276_18240	COG2244	polysaccharide biosynthetic process
J5276_18255	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5276_18285	COG0438	transferase activity, transferring glycosyl groups
J5276_18290	COG0438	transferase activity, transferring glycosyl groups
J5276_18305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_18310	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
J5276_18310	COG2273	Hydrolase Family 16
J5276_18325	COG3842	ATPase activity
J5276_18330	COG3833	ABC-type maltose transport systems, permease component
J5276_18385	COG1396	sequence-specific DNA binding
J5276_18395	COG1129	ABC transporter
J5276_18400	COG4214	carbohydrate transport
J5276_18405	COG4213	ABC transporter substrate-binding protein
J5276_18420	COG0346	lactoylglutathione lyase activity
J5276_18425	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5276_18425	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
J5276_18430	COG4770	biotin carboxylase activity
J5276_18440	COG0625	glutathione transferase activity
J5276_18445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J5276_18450	COG1396	sequence-specific DNA binding
J5276_18450	COG3800	Transcriptional regulator
J5276_18460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5276_18470	COG0300	oxidoreductase activity
J5276_18480	COG2096	Adenosyltransferase
J5276_18490	COG2086	electron transfer activity
J5276_18500	COG1250	3-hydroxyacyl-CoA dehydrogenase
J5276_18505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J5276_18510	COG0165	Argininosuccinate lyase
J5276_18545	COG2884	Cell division ATP-binding protein ftsE
J5276_18565	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J5276_18580	COG0287	Prephenate dehydrogenase
J5276_18585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5276_18590	COG2226	methyltransferase
J5276_18595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_18610	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J5276_18615	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
J5276_18650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J5276_18655	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J5276_18665	COG4974	Belongs to the 'phage' integrase family
J5276_18670	COG0825	malonyl-CoA metabolic process
J5276_18675	COG3034	peptidoglycan biosynthetic process
J5276_18680	COG0425	Belongs to the sulfur carrier protein TusA family
J5276_18685	COG0523	cobalamin synthesis protein
J5276_18690	COG1686	Belongs to the peptidase S11 family
J5276_18695	COG1473	amidohydrolase
J5276_18705	COG4953	penicillin-binding protein 1C
J5276_18710	COG2373	Large extracellular alpha-helical protein
J5276_18715	COG2835	tetraacyldisaccharide 4'-kinase activity
J5276_18725	COG3118	belongs to the thioredoxin family
J5276_18780	COG2801	Transposase and inactivated derivatives
J5276_18880	COG4373	Mu-like prophage FluMu protein gp28
J5276_18885	COG4383	Mu-like prophage protein gp29
J5276_18910	COG4397	Mu-like prophage major head subunit gpT
J5276_18980	COG3299	homolog of phage Mu protein gp47
J5276_19020	COG0482	sulfurtransferase activity
J5276_19035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J5276_19050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J5276_19055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J5276_19060	COG0037	tRNA processing
J5276_19070	COG2885	chlorophyll binding
J5276_19075	COG0823	Involved in the tonB-independent uptake of proteins
J5276_19095	COG0824	Thioesterase
J5276_19105	COG0494	nUDIX hydrolase
J5276_19120	COG2255	four-way junction helicase activity
J5276_19125	COG0632	four-way junction helicase activity
J5276_19130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J5276_19135	COG2972	Histidine kinase
J5276_19135	COG0840	transmembrane signaling receptor activity
J5276_19140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_19145	COG0217	transcriptional regulatory protein
J5276_19160	COG1692	metallophosphoesterase
J5276_19170	COG1253	flavin adenine dinucleotide binding
J5276_19210	COG0126	phosphoglycerate kinase activity
J5276_19215	COG3588	fructose-bisphosphate aldolase
J5276_19240	COG0254	rRNA binding
J5276_19245	COG1132	(ABC) transporter
J5276_19265	COG0483	inositol monophosphate 1-phosphatase activity
J5276_19295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J5276_19300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J5276_19305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J5276_19310	COG0457	Tetratricopeptide repeat
J5276_19315	COG3750	Belongs to the UPF0335 family
J5276_19335	COG0469	pyruvate kinase activity
J5276_19340	COG3108	Peptidase M15
J5276_19345	COG2204	response regulator
J5276_19350	COG1164	Oligoendopeptidase f
J5276_19355	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J5276_19365	COG5310	Homospermidine synthase
J5276_19375	COG0737	Belongs to the 5'-nucleotidase family
J5276_19380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J5276_19385	COG0330	HflC and HflK could
J5276_19410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J5276_19415	COG2951	lytic endotransglycosylase activity
J5276_19430	COG2205	protein histidine kinase activity
J5276_19445	COG0067	glutamate synthase
J5276_19445	COG0069	glutamate synthase activity
J5276_19445	COG0070	glutamate synthase
J5276_19460	COG2205	protein histidine kinase activity
J5276_19465	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
J5276_19470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J5276_19480	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J5276_19495	COG0252	asparaginase activity
J5276_19505	COG1027	Aspartate ammonia-lyase
J5276_19510	COG2186	Transcriptional regulator
J5276_19535	COG3239	Fatty acid desaturase
J5276_19555	COG0583	DNA-binding transcription factor activity
J5276_19575	COG3842	ATPase activity
J5276_19580	COG1177	transmembrane transport
J5276_19600	COG1012	belongs to the aldehyde dehydrogenase family
J5276_19605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_19615	COG2267	carboxylic ester hydrolase activity
J5276_19630	COG1126	abc transporter atp-binding protein
J5276_19635	COG0765	amino acid transport
J5276_19655	COG0174	glutamine synthetase
J5276_19660	COG0069	glutamate synthase activity
J5276_19665	COG2218	PFAM glutamate synthase alpha subunit domain protein
J5276_19670	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J5276_19690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_19700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_19705	COG0601	transmembrane transport
J5276_19710	COG0747	negative chemotaxis
J5276_19720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
J5276_19725	COG1454	alcohol dehydrogenase
J5276_19770	COG2307	Protein conserved in bacteria
J5276_19770	COG2308	Evidence 4 Homologs of previously reported genes of
J5276_19785	COG0488	(ABC) transporter
J5276_19790	COG1304	FMN binding
J5276_19795	COG1846	Transcriptional regulator
J5276_19800	COG0840	transmembrane signaling receptor activity
J5276_19805	COG1070	Carbohydrate kinase
J5276_19810	COG1830	Aldolase
J5276_19815	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J5276_19820	COG0667	Aldo Keto reductase
J5276_19830	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_19835	COG1129	ABC transporter
J5276_19840	COG1879	ABC-type sugar transport system periplasmic component
J5276_19870	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_19885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5276_19900	COG0395	ABC-type sugar transport system, permease component
J5276_19910	COG3842	ATPase activity
J5276_19915	COG3842	ATPase activity
J5276_19930	COG1648	precorrin-2 dehydrogenase activity
J5276_19930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J5276_19935	COG0243	molybdopterin cofactor binding
J5276_19945	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J5276_19950	COG1116	anion transmembrane transporter activity
J5276_19955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_19960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_19970	COG3707	response regulator
J5276_19975	COG1802	Transcriptional regulator
J5276_19980	COG1914	H( )-stimulated, divalent metal cation uptake system
J5276_19985	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J5276_19990	COG4336	lyase activity
J5276_19995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
J5276_20000	COG4770	biotin carboxylase activity
J5276_20005	COG0366	Alpha amylase catalytic
J5276_20015	COG4771	TonB-dependent receptor
J5276_20020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J5276_20040	COG1414	Transcriptional regulator
J5276_20045	COG1475	DNA binding
J5276_20050	COG1192	Involved in chromosome partitioning
J5276_20080	COG0596	Alpha beta hydrolase
J5276_20085	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
J5276_20095	COG2986	histidine ammonia-lyase
J5276_20100	COG1228	amidohydrolase
J5276_20105	COG0402	S-adenosylhomocysteine deaminase activity
J5276_20145	COG0511	ligase activity, forming carbon-carbon bonds
J5276_20150	COG0439	Biotin carboxylase
J5276_20165	COG1984	allophanate hydrolase subunit 2
J5276_20170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J5276_20175	COG0436	Aminotransferase
J5276_20185	COG4221	oxidoreductase activity
J5276_20190	COG0765	amino acid transport
J5276_20195	COG0765	amino acid transport
J5276_20200	COG1126	abc transporter atp-binding protein
J5276_20205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_20210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5276_20215	COG0010	Belongs to the arginase family
J5276_20220	COG1126	abc transporter atp-binding protein
J5276_20230	COG0765	amino acid transport
J5276_20245	COG0640	Transcriptional regulator
J5276_20255	COG0431	NADPH-dependent FMN reductase
J5276_20265	COG0798	PFAM Bile acid sodium symporter
J5276_20275	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5276_20280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_20290	COG3842	ATPase activity
J5276_20295	COG0395	ABC-type sugar transport system, permease component
J5276_20300	COG1175	transmembrane transport
J5276_20310	COG0673	inositol 2-dehydrogenase activity
J5276_20315	COG0673	inositol 2-dehydrogenase activity
J5276_20355	COG0583	DNA-binding transcription factor activity
J5276_20360	COG0477	Major facilitator Superfamily
J5276_20370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_20380	COG4172	Belongs to the ABC transporter superfamily
J5276_20385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_20390	COG0601	transmembrane transport
J5276_20405	COG0277	FAD linked oxidase domain protein
J5276_20425	COG2205	protein histidine kinase activity
J5276_20430	COG0745	RESPONSE REGULATOR receiver
J5276_20435	COG0671	phosphoesterase, PA-phosphatase related
J5276_20485	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J5276_20495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
J5276_20500	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_20505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J5276_20520	COG0010	Belongs to the arginase family
J5276_20530	COG0697	spore germination
J5276_20535	COG0673	inositol 2-dehydrogenase activity
J5276_20555	COG0477	Major facilitator Superfamily
J5276_20560	COG0642	Histidine kinase
J5276_20570	COG2194	sulfuric ester hydrolase activity
J5276_20580	COG0583	DNA-binding transcription factor activity
J5276_20585	COG4774	siderophore transport
J5276_20600	COG1120	ATPase activity
J5276_20615	COG2137	regulation of response to DNA damage stimulus
J5276_20620	COG3386	PFAM SMP-30 Gluconolaconase
J5276_20630	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_20635	COG1129	ABC transporter
J5276_20640	COG1879	ABC-type sugar transport system periplasmic component
J5276_20645	COG4585	Histidine kinase
J5276_20650	COG2197	response regulator
J5276_20660	COG2133	pyrroloquinoline quinone binding
J5276_20670	COG0500	methyltransferase
J5276_20675	COG0564	pseudouridine synthase activity
J5276_20690	COG4175	Glycine betaine
J5276_20690	COG0517	IMP dehydrogenase activity
J5276_20695	COG4176	ABC-type proline glycine betaine transport system permease component
J5276_20705	COG0784	Response regulator, receiver
J5276_20705	COG4191	Histidine kinase
J5276_20715	COG0489	protein tyrosine kinase activity
J5276_20715	COG3206	protein involved in exopolysaccharide biosynthesis
J5276_20720	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J5276_20725	COG1215	transferase activity, transferring glycosyl groups
J5276_20730	COG1215	transferase activity, transferring glycosyl groups
J5276_20735	COG1215	transferase activity, transferring glycosyl groups
J5276_20740	COG0438	transferase activity, transferring glycosyl groups
J5276_20745	COG2273	Hydrolase Family 16
J5276_20750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J5276_20755	COG2244	polysaccharide biosynthetic process
J5276_20760	COG0463	Glycosyl transferase, family 2
J5276_20765	COG2327	Polysaccharide pyruvyl transferase
J5276_20770	COG1215	transferase activity, transferring glycosyl groups
J5276_20790	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J5276_20795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_20810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5276_20810	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_20835	COG1523	belongs to the glycosyl hydrolase 13 family
J5276_20840	COG0033	Phosphoglucomutase
J5276_20845	COG0297	glycogen (starch) synthase activity
J5276_20850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J5276_20855	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J5276_20860	COG0058	SHG alpha-glucan phosphorylase activity
J5276_20870	COG1794	racemase activity, acting on amino acids and derivatives
J5276_20875	COG1522	sequence-specific DNA binding
J5276_20885	COG2084	Dehydrogenase
J5276_20890	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_20895	COG1063	alcohol dehydrogenase
J5276_20905	COG4988	ABC transporter
J5276_20910	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J5276_20920	COG1294	oxidase, subunit
J5276_20950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
J5276_20955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J5276_20985	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J5276_20990	COG0539	negative regulation of cytoplasmic translation
J5276_21020	COG4221	oxidoreductase activity
J5276_21025	COG0006	proline dipeptidase activity
J5276_21030	COG0747	negative chemotaxis
J5276_21035	COG0601	transmembrane transport
J5276_21040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_21045	COG0444	Belongs to the ABC transporter superfamily
J5276_21050	COG4608	Belongs to the ABC transporter superfamily
J5276_21065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_21080	COG0411	ABC transporter
J5276_21090	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5276_21110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J5276_21115	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_21135	COG4993	Dehydrogenase
J5276_21140	COG3685	Protein conserved in bacteria
J5276_21150	COG0693	protein deglycase activity
J5276_21175	COG0189	ligase activity
J5276_21180	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J5276_21185	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J5276_21195	COG0435	Glutathione S-transferase
J5276_21200	COG0583	DNA-binding transcription factor activity
J5276_21205	COG1012	belongs to the aldehyde dehydrogenase family
J5276_21210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J5276_21215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J5276_21220	COG1116	anion transmembrane transporter activity
J5276_21230	COG1522	sequence-specific DNA binding
J5276_21245	COG0784	Response regulator, receiver
J5276_21265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5276_21285	COG0019	diaminopimelate decarboxylase activity
J5276_21300	COG0527	aspartate kinase activity
J5276_21310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J5276_21315	COG2890	protein-(glutamine-N5) methyltransferase activity
J5276_21325	COG0542	response to heat
J5276_21330	COG0741	lytic transglycosylase activity
J5276_21330	COG0739	heme binding
J5276_21330	COG1196	nuclear chromosome segregation
J5276_21365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5276_21370	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J5276_21385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_21390	COG1309	transcriptional regulator
J5276_21395	COG4221	oxidoreductase activity
J5276_21400	COG1902	pentaerythritol trinitrate reductase activity
J5276_21405	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_21410	COG0604	alcohol dehydrogenase
J5276_21420	COG0243	molybdopterin cofactor binding
J5276_21425	COG2814	Major facilitator Superfamily
J5276_21435	COG0492	ferredoxin-NADP+ reductase activity
J5276_21445	COG4566	intracellular signal transduction
J5276_21450	COG4566	intracellular signal transduction
J5276_21460	COG2140	Oxalate decarboxylase
J5276_21465	COG0783	Belongs to the Dps family
J5276_21475	COG0583	DNA-binding transcription factor activity
J5276_21485	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_21490	COG1846	Transcriptional regulator
J5276_21505	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
J5276_21510	COG0583	DNA-binding transcription factor activity
J5276_21515	COG0346	lactoylglutathione lyase activity
J5276_21535	COG1574	metal-dependent hydrolase with the TIM-barrel fold
J5276_21560	COG2080	2 iron, 2 sulfur cluster binding
J5276_21565	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
J5276_21570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J5276_21575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
J5276_21580	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J5276_21600	COG1278	Cold shock
J5276_21630	COG2986	histidine ammonia-lyase
J5276_21650	COG4172	Belongs to the ABC transporter superfamily
J5276_21655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_21660	COG0601	transmembrane transport
J5276_21665	COG4166	transmembrane transport
J5276_21670	COG0840	transmembrane signaling receptor activity
J5276_21680	COG3300	MHYT domain
J5276_21680	COG5001	Diguanylate cyclase
J5276_21700	COG1609	Transcriptional regulator
J5276_21715	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_21720	COG1735	metal-dependent hydrolase with the TIM-barrel fold
J5276_21745	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
J5276_21750	COG1049	propionate catabolic process, 2-methylcitrate cycle
J5276_21760	COG0367	asparagine synthase
J5276_21770	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_21775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J5276_21795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J5276_21795	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_21800	COG4311	Sarcosine oxidase, delta subunit
J5276_21805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_21810	COG4977	sequence-specific DNA binding
J5276_21815	COG1129	ABC transporter
J5276_21825	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_21840	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_21845	COG0246	Mannitol dehydrogenase
J5276_21850	COG1312	Catalyzes the dehydration of D-mannonate
J5276_21870	COG1309	transcriptional regulator
J5276_21875	COG1063	alcohol dehydrogenase
J5276_21885	COG1879	ABC-type sugar transport system periplasmic component
J5276_21895	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_21915	COG0477	Major facilitator Superfamily
J5276_21925	COG0483	inositol monophosphate 1-phosphatase activity
J5276_21950	COG1178	ABC-type Fe3 transport system permease component
J5276_21955	COG3842	ATPase activity
J5276_21985	COG1253	flavin adenine dinucleotide binding
J5276_22000	COG3842	ATPase activity
J5276_22005	COG0395	ABC-type sugar transport system, permease component
J5276_22010	COG1175	transmembrane transport
J5276_22015	COG1653	transport
J5276_22025	COG0673	inositol 2-dehydrogenase activity
J5276_22030	COG1609	Transcriptional regulator
J5276_22045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_22065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J5276_22075	COG0668	transmembrane transport
J5276_22105	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_22110	COG3433	isochorismatase activity
J5276_22110	COG1535	isochorismatase
J5276_22115	COG1021	2,3-dihydroxybenzoate-AMP ligase
J5276_22120	COG1169	isochorismate synthase
J5276_22130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J5276_22130	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J5276_22135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J5276_22145	COG2375	cellular response to nickel ion
J5276_22155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_22160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_22165	COG1120	ATPase activity
J5276_22170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_22180	COG1629	transport
J5276_22180	COG4774	siderophore transport
J5276_22185	COG1960	acyl-CoA dehydrogenase activity
J5276_22190	COG0583	DNA-binding transcription factor activity
J5276_22195	COG1609	Transcriptional regulator
J5276_22205	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_22225	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J5276_22235	COG1473	amidohydrolase
J5276_22250	COG0747	negative chemotaxis
J5276_22255	COG0601	transmembrane transport
J5276_22260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_22265	COG0444	Belongs to the ABC transporter superfamily
J5276_22270	COG4608	Belongs to the ABC transporter superfamily
J5276_22275	COG0583	DNA-binding transcription factor activity
J5276_22280	COG0747	negative chemotaxis
J5276_22290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_22300	COG0693	protein deglycase activity
J5276_22310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_22315	COG0601	transmembrane transport
J5276_22325	COG1473	amidohydrolase
J5276_22330	COG4172	Belongs to the ABC transporter superfamily
J5276_22335	COG2390	Transcriptional regulator
J5276_22345	COG1175	transmembrane transport
J5276_22350	COG0395	ABC-type sugar transport system, permease component
J5276_22395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J5276_22405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J5276_22410	COG1414	Transcriptional regulator
J5276_22415	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_22420	COG5487	UPF0391 membrane protein
J5276_22425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5276_22430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J5276_22435	COG1121	(ABC) transporter
J5276_22440	COG0803	Belongs to the bacterial solute-binding protein 9 family
J5276_22450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J5276_22455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J5276_22460	COG3273	potassium ion transport
J5276_22460	COG0471	metal ion transport
J5276_22465	COG1253	flavin adenine dinucleotide binding
J5276_22470	COG1309	transcriptional regulator
J5276_22485	COG1609	Transcriptional regulator
J5276_22490	COG1070	Carbohydrate kinase
J5276_22495	COG2115	Belongs to the xylose isomerase family
J5276_22505	COG0778	Nitroreductase
J5276_22510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5276_22515	COG2011	ABC-type metal ion transport system permease component
J5276_22525	COG3300	MHYT domain
J5276_22525	COG5001	Diguanylate cyclase
J5276_22530	COG1054	Belongs to the UPF0176 family
J5276_22540	COG2954	triphosphatase activity
J5276_22545	COG0800	Aldolase
J5276_22565	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
J5276_22600	COG0523	cobalamin synthesis protein
J5276_22610	COG1846	Transcriptional regulator
J5276_22615	COG1609	Transcriptional regulator
J5276_22620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5276_22625	COG0673	inositol 2-dehydrogenase activity
J5276_22630	COG3718	enzyme involved in inositol metabolism
J5276_22640	COG3962	Belongs to the TPP enzyme family
J5276_22645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_22655	COG3842	ATPase activity
J5276_22675	COG0683	leucine binding
J5276_22690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_22700	COG0747	negative chemotaxis
J5276_22715	COG1082	Xylose isomerase domain protein TIM barrel
J5276_22715	COG3185	4-Hydroxyphenylpyruvate dioxygenase
J5276_22725	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J5276_22730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J5276_22735	COG1126	abc transporter atp-binding protein
J5276_22740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_22745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_22750	COG0765	amino acid transport
J5276_22755	COG0765	amino acid transport
J5276_22765	COG3485	protocatechuate 3,4-dioxygenase
J5276_22770	COG3485	protocatechuate 3,4-dioxygenase
J5276_22775	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J5276_22785	COG0583	DNA-binding transcription factor activity
J5276_22800	COG1414	Transcriptional regulator
J5276_22810	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J5276_22815	COG0183	Belongs to the thiolase family
J5276_22820	COG1609	Transcriptional regulator
J5276_22830	COG1082	Xylose isomerase domain protein TIM barrel
J5276_22835	COG0673	inositol 2-dehydrogenase activity
J5276_22845	COG1609	Transcriptional regulator
J5276_22850	COG0395	ABC-type sugar transport system, permease component
J5276_22855	COG1175	transmembrane transport
J5276_22860	COG3842	ATPase activity
J5276_22870	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
J5276_22900	COG3842	ATPase activity
J5276_22905	COG4149	molybdate abc transporter
J5276_22915	COG0584	glycerophosphoryl diester phosphodiesterase
J5276_22920	COG0483	inositol monophosphate 1-phosphatase activity
J5276_22935	COG3842	ATPase activity
J5276_22940	COG1177	transmembrane transport
J5276_22960	COG0385	Bile acid
J5276_22970	COG1132	(ABC) transporter
J5276_23000	COG1215	transferase activity, transferring glycosyl groups
J5276_23010	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J5276_23015	COG1091	dTDP-4-dehydrorhamnose reductase activity
J5276_23020	COG1088	dTDP-glucose 4,6-dehydratase activity
J5276_23025	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
J5276_23040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_23045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_23050	COG1120	ATPase activity
J5276_23055	COG4774	siderophore transport
J5276_23060	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J5276_23075	COG1609	Transcriptional regulator
J5276_23080	COG1233	COG1233 Phytoene dehydrogenase and related
J5276_23095	COG0395	ABC-type sugar transport system, permease component
J5276_23100	COG3842	ATPase activity
J5276_23105	COG4608	Belongs to the ABC transporter superfamily
J5276_23110	COG0444	Belongs to the ABC transporter superfamily
J5276_23115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_23120	COG0601	transmembrane transport
J5276_23125	COG2186	Transcriptional regulator
J5276_23135	COG0747	negative chemotaxis
J5276_23145	COG3300	MHYT domain
J5276_23145	COG5001	Diguanylate cyclase
J5276_23150	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_23160	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J5276_23170	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
J5276_23175	COG0306	phosphate transporter
J5276_23180	COG1392	Phosphate transport regulator
J5276_23200	COG0745	RESPONSE REGULATOR receiver
J5276_23205	COG5002	protein histidine kinase activity
J5276_23220	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
J5276_23235	COG4774	siderophore transport
J5276_23245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_23250	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_23255	COG1120	ATPase activity
J5276_23260	COG1733	regulation of RNA biosynthetic process
J5276_23285	COG1012	belongs to the aldehyde dehydrogenase family
J5276_23290	COG0583	DNA-binding transcription factor activity
J5276_23300	COG3119	arylsulfatase activity
J5276_23305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J5276_23310	COG3842	ATPase activity
J5276_23315	COG0165	Argininosuccinate lyase
J5276_23320	COG0395	ABC-type sugar transport system, permease component
J5276_23325	COG1175	transmembrane transport
J5276_23330	COG2182	Extracellular solute-binding protein
J5276_23335	COG1940	carbohydrate kinase activity
J5276_23360	COG1486	melibiose metabolic process
J5276_23365	COG0747	negative chemotaxis
J5276_23370	COG0601	transmembrane transport
J5276_23375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_23380	COG4172	Belongs to the ABC transporter superfamily
J5276_23385	COG1486	melibiose metabolic process
J5276_23390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_23395	COG0842	Transport permease protein
J5276_23395	COG1129	ABC transporter
J5276_23400	COG0842	Transport permease protein
J5276_23415	COG0784	Response regulator, receiver
J5276_23420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J5276_23430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_23435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_23450	COG0765	amino acid transport
J5276_23460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_23470	COG3938	Belongs to the proline racemase family
J5276_23485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_23490	COG0765	amino acid transport
J5276_23495	COG0765	amino acid transport
J5276_23505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J5276_23520	COG0402	S-adenosylhomocysteine deaminase activity
J5276_23530	COG0601	transmembrane transport
J5276_23535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_23545	COG0402	S-adenosylhomocysteine deaminase activity
J5276_23550	COG0444	Belongs to the ABC transporter superfamily
J5276_23555	COG4608	Belongs to the ABC transporter superfamily
J5276_23560	COG1802	Transcriptional regulator
J5276_23565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_23590	COG3383	formate dehydrogenase (NAD+) activity
J5276_23600	COG2223	nitrite transmembrane transporter activity
J5276_23605	COG0456	acetyltransferase
J5276_23635	COG3237	CsbD-like
J5276_23640	COG2197	response regulator
J5276_23645	COG3181	Tripartite tricarboxylate transporter family receptor
J5276_23655	COG5265	(ABC) transporter
J5276_23660	COG0640	Transcriptional regulator
J5276_23675	COG0753	catalase activity
J5276_23720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5276_23740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J5276_23745	COG4251	negative regulation of phosphorylation
J5276_23745	COG5001	Diguanylate cyclase
J5276_23745	COG2203	Gaf domain
J5276_23745	COG3706	GGDEF domain
J5276_23755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J5276_23760	COG3046	protein related to deoxyribodipyrimidine photolyase
J5276_23810	COG0438	transferase activity, transferring glycosyl groups
J5276_23810	COG1216	Glycosyl transferase, family 2
J5276_23830	COG0156	8-amino-7-oxononanoate synthase activity
J5276_23835	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J5276_23840	COG1368	sulfuric ester hydrolase activity
J5276_23975	COG1595	DNA-templated transcription, initiation
J5276_23985	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_23990	COG1309	transcriptional regulator
J5276_24000	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
J5276_24010	COG1126	abc transporter atp-binding protein
J5276_24015	COG0765	amino acid transport
J5276_24020	COG0765	amino acid transport
J5276_24025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_24030	COG3608	succinylglutamate desuccinylase aspartoacylase
J5276_24035	COG0006	proline dipeptidase activity
J5276_24040	COG2423	ornithine cyclodeaminase activity
J5276_24045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J5276_24050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_24055	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J5276_24065	COG1522	sequence-specific DNA binding
J5276_24285	COG4106	trans-aconitate 2-methyltransferase activity
J5276_24305	COG2814	Major facilitator Superfamily
J5276_24310	COG0583	DNA-binding transcription factor activity
J5276_24325	COG0747	negative chemotaxis
J5276_24330	COG0601	transmembrane transport
J5276_24335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_24340	COG4172	Belongs to the ABC transporter superfamily
J5276_24355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J5276_24395	COG0406	alpha-ribazole phosphatase activity
J5276_24435	COG2801	Transposase and inactivated derivatives
J5276_24500	COG1012	belongs to the aldehyde dehydrogenase family
J5276_24510	COG2211	Major facilitator Superfamily
J5276_24525	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_24530	COG1129	ABC transporter
J5276_24535	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_24540	COG1053	succinate dehydrogenase
J5276_24570	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_24575	COG0625	glutathione transferase activity
J5276_24600	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_24605	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_24610	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_24615	COG1129	ABC transporter
J5276_24690	COG1802	Transcriptional regulator
J5276_24695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_24700	COG1012	belongs to the aldehyde dehydrogenase family
J5276_24715	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_24725	COG4175	Glycine betaine
J5276_24725	COG0517	IMP dehydrogenase activity
J5276_24730	COG4176	ABC-type proline glycine betaine transport system permease component
J5276_24735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J5276_24745	COG0446	pyridine nucleotide-disulphide oxidoreductase
J5276_24745	COG1902	pentaerythritol trinitrate reductase activity
J5276_24755	COG2086	electron transfer activity
J5276_24780	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J5276_24785	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J5276_24790	COG3791	Glutathione-dependent formaldehyde-activating
J5276_24795	COG0006	proline dipeptidase activity
J5276_24800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5276_24835	COG1802	Transcriptional regulator
J5276_24840	COG0747	negative chemotaxis
J5276_24845	COG0601	transmembrane transport
J5276_24850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_24860	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_24865	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_24870	COG1609	Transcriptional regulator
J5276_24875	COG3250	beta-galactosidase activity
J5276_24885	COG1175	transmembrane transport
J5276_24890	COG0395	ABC-type sugar transport system, permease component
J5276_24910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J5276_24935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_24940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_24955	COG0596	Alpha beta hydrolase
J5276_24980	COG1120	ATPase activity
J5276_24985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5276_25000	COG0019	diaminopimelate decarboxylase activity
J5276_25010	COG4264	IucA IucC family
J5276_25015	COG4264	IucA IucC family
J5276_25030	COG2423	ornithine cyclodeaminase activity
J5276_25035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J5276_25045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_25060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J5276_25075	COG4598	ABC transporter
J5276_25125	COG1192	Involved in chromosome partitioning
J5276_25195	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
J5276_25200	COG2948	multi-organism process
J5276_25230	COG1196	nuclear chromosome segregation
J5276_25230	COG0741	lytic transglycosylase activity
J5276_25230	COG0739	heme binding
J5276_25235	COG3451	type IV secretory pathway VirB4
J5276_25275	COG3831	ATPase activity
J5276_25285	COG0776	regulation of translation
J5276_25360	COG1414	Transcriptional regulator
J5276_25365	COG1475	DNA binding
J5276_25370	COG1192	Involved in chromosome partitioning
J5276_25430	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
J5276_25445	COG0464	growth
J5276_25470	COG0778	Nitroreductase
J5276_25475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_25480	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
J5276_25495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J5276_25505	COG0583	DNA-binding transcription factor activity
J5276_25515	COG0235	Class ii aldolase
J5276_25520	COG0583	DNA-binding transcription factor activity
J5276_25545	COG1505	serine-type exopeptidase activity
J5276_25565	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_25570	COG1733	regulation of RNA biosynthetic process
J5276_25580	COG0477	Major facilitator Superfamily
J5276_25585	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_25590	COG1794	racemase activity, acting on amino acids and derivatives
J5276_25600	COG0300	oxidoreductase activity
J5276_25615	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
J5276_25620	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J5276_25630	COG0287	Prephenate dehydrogenase
J5276_25630	COG1605	Chorismate mutase
J5276_25635	COG0583	DNA-binding transcription factor activity
J5276_25640	COG0300	oxidoreductase activity
J5276_25655	COG1376	ErfK ybiS ycfS ynhG family protein
J5276_25665	COG0251	oxidation-reduction process
J5276_25700	COG0583	DNA-binding transcription factor activity
J5276_25715	COG1473	amidohydrolase
J5276_25725	COG1522	sequence-specific DNA binding
J5276_25750	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_25755	COG2085	NADP oxidoreductase coenzyme F420-dependent
J5276_25765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_25770	COG1309	transcriptional regulator
J5276_25780	COG0583	DNA-binding transcription factor activity
J5276_25800	COG0473	3-isopropylmalate dehydrogenase activity
J5276_25805	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_25815	COG4221	oxidoreductase activity
J5276_25855	COG2186	Transcriptional regulator
J5276_25865	COG0765	amino acid transport
J5276_25875	COG3842	ATPase activity
J5276_25890	COG1177	transmembrane transport
J5276_25900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_25905	COG3257	ureidoglycine aminohydrolase activity
J5276_25925	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_25940	COG0655	NAD(P)H dehydrogenase (quinone) activity
J5276_25960	COG4221	oxidoreductase activity
J5276_25975	COG0459	protein refolding
J5276_25980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J5276_25985	COG5425	PFAM Usg family protein
J5276_25995	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_26015	COG0745	RESPONSE REGULATOR receiver
J5276_26020	COG2202	Pas domain
J5276_26020	COG3920	Histidine kinase
J5276_26025	COG0784	Response regulator, receiver
J5276_26025	COG4191	Histidine kinase
J5276_26070	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_26075	COG0668	transmembrane transport
J5276_26120	COG3547	Transposase (IS116 IS110 IS902 family)
J5276_26125	COG4221	oxidoreductase activity
J5276_26145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_26155	COG0765	amino acid transport
J5276_26160	COG0765	amino acid transport
J5276_26180	COG3622	Belongs to the hyi family
J5276_26190	COG3395	kinase activity
J5276_26195	COG0235	Class ii aldolase
J5276_26345	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
J5276_26350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_26375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J5276_26380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J5276_26465	COG4221	oxidoreductase activity
J5276_26485	COG4221	oxidoreductase activity
J5276_26490	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_26500	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_26510	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_26525	COG1741	Belongs to the pirin family
J5276_26530	COG0583	DNA-binding transcription factor activity
J5276_26570	COG1120	ATPase activity
J5276_26575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_26580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_26585	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
J5276_26590	COG1629	transport
J5276_26590	COG4774	siderophore transport
J5276_26600	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J5276_26645	COG2226	methyltransferase
J5276_26655	COG0318	PFAM AMP-dependent synthetase and ligase
J5276_26675	COG0534	Mate efflux family protein
J5276_26685	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J5276_26700	COG3609	addiction module antidote protein, CC2985 family
J5276_26715	COG1902	pentaerythritol trinitrate reductase activity
J5276_26720	COG1609	Transcriptional regulator
J5276_26730	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_26745	COG0673	inositol 2-dehydrogenase activity
J5276_26755	COG1802	Transcriptional regulator
J5276_26790	COG0840	transmembrane signaling receptor activity
J5276_26825	COG0587	DNA-directed DNA polymerase activity
J5276_26845	COG5489	Protein of unknown function (DUF736)
J5276_26855	COG0776	regulation of translation
J5276_26860	COG3831	ATPase activity
J5276_26885	COG0577	efflux transmembrane transporter activity
J5276_26895	COG1414	Transcriptional regulator
J5276_26905	COG1454	alcohol dehydrogenase
J5276_26910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J5276_26965	COG3838	Conjugal transfer protein Trbc
J5276_26970	COG3702	type iv secretory pathway
J5276_26975	COG3451	type IV secretory pathway VirB4
J5276_26990	COG3704	protein secretion by the type IV secretion system
J5276_27000	COG3736	Type IV secretory pathway, component VirB8
J5276_27005	COG3504	Conjugal transfer protein
J5276_27010	COG2948	multi-organism process
J5276_27015	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
J5276_27030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_27035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J5276_27045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J5276_27065	COG4191	Histidine kinase
J5276_27065	COG0784	Response regulator, receiver
J5276_27080	COG4691	Plasmid stability protein
J5276_27085	COG1487	ribonuclease activity
J5276_27090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_27100	COG2186	Transcriptional regulator
J5276_27105	COG0747	negative chemotaxis
J5276_27110	COG0601	transmembrane transport
J5276_27115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_27120	COG4172	Belongs to the ABC transporter superfamily
J5276_27125	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_27145	COG1595	DNA-templated transcription, initiation
J5276_27160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J5276_27170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_27175	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J5276_27180	COG1120	ATPase activity
J5276_27190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
J5276_27195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J5276_27210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J5276_27240	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_27245	COG3842	ATPase activity
J5276_27250	COG0483	inositol monophosphate 1-phosphatase activity
J5276_27255	COG0628	permease
J5276_27270	COG3734	2-keto-3-deoxy-galactonokinase
J5276_27275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J5276_27280	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_27290	COG1175	transmembrane transport
J5276_27295	COG0395	ABC-type sugar transport system, permease component
J5276_27300	COG3842	ATPase activity
J5276_27305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J5276_27310	COG1414	Transcriptional regulator
J5276_27315	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_27320	COG2207	Transcriptional regulator
J5276_27330	COG0583	DNA-binding transcription factor activity
J5276_27335	COG0667	Aldo Keto reductase
J5276_27340	COG0583	DNA-binding transcription factor activity
J5276_27345	COG0604	alcohol dehydrogenase
J5276_27350	COG1609	Transcriptional regulator
J5276_27355	COG1082	Xylose isomerase domain protein TIM barrel
J5276_27360	COG0673	inositol 2-dehydrogenase activity
J5276_27365	COG1082	Xylose isomerase domain protein TIM barrel
J5276_27375	COG0405	Gamma-glutamyltransferase
J5276_27380	COG1120	ATPase activity
J5276_27395	COG4774	siderophore transport
J5276_27415	COG1215	transferase activity, transferring glycosyl groups
J5276_27445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J5276_27460	COG2390	Transcriptional regulator
J5276_27465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J5276_27470	COG3958	Transketolase
J5276_27475	COG3959	Transketolase, thiamine diphosphate binding domain
J5276_27480	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_27490	COG1129	ABC transporter
J5276_27495	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_27500	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_27525	COG3547	Transposase (IS116 IS110 IS902 family)
J5276_27530	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_27550	COG0583	DNA-binding transcription factor activity
J5276_27565	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
J5276_27570	COG1741	Belongs to the pirin family
J5276_27575	COG1335	isochorismatase
J5276_27580	COG0583	DNA-binding transcription factor activity
J5276_27585	COG1733	regulation of RNA biosynthetic process
J5276_27590	COG3321	synthase
J5276_27590	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_27590	COG0604	alcohol dehydrogenase
J5276_27595	COG0583	DNA-binding transcription factor activity
J5276_27615	COG1017	nitric oxide dioxygenase activity
J5276_27615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J5276_27620	COG0625	glutathione transferase activity
J5276_27630	COG0583	DNA-binding transcription factor activity
J5276_27655	COG1349	DNA-binding transcription factor activity
J5276_27660	COG1879	ABC-type sugar transport system periplasmic component
J5276_27665	COG1129	ABC transporter
J5276_27670	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_27675	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_27695	COG1012	belongs to the aldehyde dehydrogenase family
J5276_27705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J5276_27745	COG4302	ethanolamine ammonia-lyase activity
J5276_27770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_27775	COG1349	DNA-binding transcription factor activity
J5276_27780	COG4608	Belongs to the ABC transporter superfamily
J5276_27790	COG0601	transmembrane transport
J5276_27795	COG0747	negative chemotaxis
J5276_27820	COG0534	Mate efflux family protein
J5276_27825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J5276_27845	COG4774	siderophore transport
J5276_27850	COG1309	transcriptional regulator
J5276_27860	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
J5276_27865	COG1454	alcohol dehydrogenase
J5276_27875	COG4948	Mandelate Racemase Muconate Lactonizing
J5276_27880	COG0747	negative chemotaxis
J5276_27885	COG0747	negative chemotaxis
J5276_27890	COG0601	transmembrane transport
J5276_27895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_27905	COG4172	Belongs to the ABC transporter superfamily
J5276_27960	COG2963	transposase activity
J5276_27965	COG3436	PFAM IS66 Orf2 family protein
J5276_27980	COG0583	DNA-binding transcription factor activity
J5276_27995	COG1309	transcriptional regulator
J5276_28010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_28015	COG4215	(ABC) transporter
J5276_28025	COG0697	spore germination
J5276_28045	COG0835	chemotaxis
J5276_28050	COG0840	transmembrane signaling receptor activity
J5276_28060	COG2207	Transcriptional regulator
J5276_28070	COG1129	ABC transporter
J5276_28075	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_28095	COG3706	GGDEF domain
J5276_28125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J5276_28145	COG0517	IMP dehydrogenase activity
J5276_28160	COG5001	Diguanylate cyclase
J5276_28205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J5276_28220	COG1902	pentaerythritol trinitrate reductase activity
J5276_28230	COG0583	DNA-binding transcription factor activity
J5276_28235	COG4702	Belongs to the UPF0303 family
J5276_28240	COG0823	Involved in the tonB-independent uptake of proteins
J5276_28255	COG3842	ATPase activity
J5276_28265	COG1175	transmembrane transport
J5276_28270	COG1653	transport
J5276_28315	COG2963	transposase activity
J5276_28325	COG4372	Transposase
J5276_28335	COG1733	regulation of RNA biosynthetic process
J5276_28370	COG0436	Aminotransferase
J5276_28445	COG0745	RESPONSE REGULATOR receiver
J5276_28455	COG1192	Involved in chromosome partitioning
J5276_28545	COG1475	DNA binding
J5276_28550	COG0640	Transcriptional regulator
J5276_28575	COG3436	PFAM IS66 Orf2 family protein
J5276_28580	COG4372	Transposase
J5276_28580	COG4372	Transposase
J5276_28640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_28645	COG0584	glycerophosphoryl diester phosphodiesterase
J5276_28650	COG0483	inositol monophosphate 1-phosphatase activity
J5276_28750	COG1396	sequence-specific DNA binding
J5276_28755	COG3621	Patatin-like phospholipase
J5276_28790	COG0776	regulation of translation
J5276_28795	COG3831	ATPase activity
J5276_28840	COG3842	ATPase activity
J5276_28880	COG0625	glutathione transferase activity
J5276_28895	COG1802	Transcriptional regulator
J5276_28910	COG0411	ABC transporter
J5276_28925	COG2084	Dehydrogenase
J5276_28930	COG0179	Fumarylacetoacetate (FAA) hydrolase
J5276_28935	COG0346	lactoylglutathione lyase activity
J5276_28945	COG2814	Major facilitator Superfamily
J5276_28965	COG3842	ATPase activity
J5276_28975	COG1177	transmembrane transport
J5276_28985	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_28990	COG1177	transmembrane transport
J5276_28995	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J5276_29000	COG3842	ATPase activity
J5276_29005	COG1012	belongs to the aldehyde dehydrogenase family
J5276_29010	COG0747	negative chemotaxis
J5276_29020	COG4372	Transposase
J5276_29025	COG3436	PFAM IS66 Orf2 family protein
J5276_29030	COG2963	transposase activity
J5276_29040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J5276_29060	COG1176	ABC-type spermidine putrescine transport system, permease component I
J5276_29065	COG3842	ATPase activity
J5276_29070	COG1840	ABC-type Fe3 transport system, periplasmic component
J5276_29095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_29100	COG4172	Belongs to the ABC transporter superfamily
J5276_29110	COG1063	alcohol dehydrogenase
J5276_29135	COG3842	ATPase activity
J5276_29145	COG0698	ribose 5-phosphate isomerase
J5276_29150	COG0395	ABC-type sugar transport system, permease component
J5276_29155	COG1175	transmembrane transport
J5276_29175	COG1902	pentaerythritol trinitrate reductase activity
J5276_29200	COG3436	PFAM IS66 Orf2 family protein
J5276_29205	COG2963	transposase activity
J5276_29285	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
J5276_29300	COG2197	response regulator
J5276_29355	COG1216	Glycosyl transferase, family 2
J5276_29375	COG3916	Acyl-homoserine-lactone synthase
J5276_29385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J5276_29390	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J5276_29420	COG0071	Belongs to the small heat shock protein (HSP20) family
J5276_29440	COG1278	Cold shock
J5276_29490	COG2963	transposase activity
J5276_29495	COG3436	PFAM IS66 Orf2 family protein
J5276_29500	COG4372	Transposase
J5276_29515	COG3620	sequence-specific DNA binding
J5276_29520	COG3550	peptidyl-serine autophosphorylation
J5276_29540	COG3077	Addiction module antitoxin, RelB DinJ family
J5276_29555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J5276_29565	COG0596	Alpha beta hydrolase
J5276_29595	COG1454	alcohol dehydrogenase
J5276_29605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J5276_29655	COG0668	transmembrane transport
J5276_29670	COG1566	PFAM secretion protein HlyD family protein
J5276_29685	COG2207	Transcriptional regulator
J5276_29695	COG4302	ethanolamine ammonia-lyase activity
J5276_29700	COG4303	Ethanolamine ammonia lyase large subunit
J5276_29720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J5276_29725	COG1349	DNA-binding transcription factor activity
J5276_29730	COG4608	Belongs to the ABC transporter superfamily
J5276_29740	COG0601	transmembrane transport
J5276_29745	COG0747	negative chemotaxis
J5276_29760	COG3842	ATPase activity
J5276_29765	COG1063	alcohol dehydrogenase
J5276_29770	COG0395	ABC-type sugar transport system, permease component
J5276_29775	COG1175	transmembrane transport
J5276_29780	COG1653	transport
J5276_29810	COG0326	Molecular chaperone. Has ATPase activity
J5276_29820	COG1881	PFAM PEBP family protein
J5276_29845	COG0778	Nitroreductase
J5276_29850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J5276_29865	COG0559	Belongs to the binding-protein-dependent transport system permease family
J5276_29890	COG0583	DNA-binding transcription factor activity
J5276_29895	COG0667	Aldo Keto reductase
J5276_29925	COG1172	Belongs to the binding-protein-dependent transport system permease family
J5276_29960	COG1028	Short-chain dehydrogenase reductase Sdr
J5276_29980	COG1278	Cold shock
J5276_29995	COG1126	abc transporter atp-binding protein
J5276_30000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J5276_30005	COG1609	Transcriptional regulator
J5276_30010	COG1192	Involved in chromosome partitioning
J5276_30015	COG1475	DNA binding
J5276_30020	COG0640	Transcriptional regulator
J5276_30035	COG0583	DNA-binding transcription factor activity
J5276_30060	COG3971	2-oxopent-4-enoate hydratase activity
J5276_30065	COG3485	protocatechuate 3,4-dioxygenase
J5276_30170	COG0835	chemotaxis
J5276_30180	COG0546	phosphoglycolate phosphatase activity
J5276_30190	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J5276_30220	COG1192	Involved in chromosome partitioning