locus-tag	class	description
At12D1_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
At12D1_00020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
At12D1_00030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
At12D1_00040	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
At12D1_00050	COG1420	regulation of RNA biosynthetic process
At12D1_00060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
At12D1_00070	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
At12D1_00080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
At12D1_00100	COG1137	ATPase activity
At12D1_00110	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
At12D1_00130	COG0616	signal peptide processing
At12D1_00140	COG0776	regulation of translation
At12D1_00160	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
At12D1_00170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
At12D1_00180	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
At12D1_00210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
At12D1_00220	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
At12D1_00230	COG0728	peptidoglycan biosynthetic process
At12D1_00250	COG0180	Tryptophanyl-tRNA synthetase
At12D1_00270	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
At12D1_00280	COG1214	PFAM Peptidase M22, glycoprotease
At12D1_00320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
At12D1_00330	COG1702	phosphate starvation-inducible protein PhoH
At12D1_00340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
At12D1_00360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
At12D1_00370	COG1396	sequence-specific DNA binding
At12D1_00380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
At12D1_00390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
At12D1_00400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_00420	COG0242	peptide deformylase activity
At12D1_00430	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
At12D1_00440	COG0101	tRNA pseudouridine synthase activity
At12D1_00460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
At12D1_00470	COG2171	N-acyltransferase activity
At12D1_00490	COG0840	transmembrane signaling receptor activity
At12D1_00500	COG1957	nucleoside hydrolase
At12D1_00510	COG0071	Belongs to the small heat shock protein (HSP20) family
At12D1_00560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
At12D1_00580	COG0218	Necessary for normal cell division and for the maintenance of normal septation
At12D1_00590	COG0706	membrane insertase activity
At12D1_00600	COG0594	ribonuclease P activity
At12D1_00610	COG0840	transmembrane signaling receptor activity
At12D1_00630	COG5002	protein histidine kinase activity
At12D1_00630	COG3850	Histidine kinase
At12D1_00640	COG2226	methyltransferase
At12D1_00660	COG3842	ATPase activity
At12D1_00670	COG1175	transmembrane transport
At12D1_00680	COG0395	ABC-type sugar transport system, permease component
At12D1_00710	COG0427	acetyl-CoA hydrolase
At12D1_00730	COG3938	Belongs to the proline racemase family
At12D1_00740	COG0418	dihydroorotase activity
At12D1_00750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
At12D1_00790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
At12D1_00800	COG0166	Belongs to the GPI family
At12D1_00810	COG0318	PFAM AMP-dependent synthetase and ligase
At12D1_00820	COG3842	ATPase activity
At12D1_00830	COG1840	ABC-type Fe3 transport system, periplasmic component
At12D1_00840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
At12D1_00850	COG4774	siderophore transport
At12D1_00930	COG2326	polyphosphate kinase activity
At12D1_00940	COG5002	protein histidine kinase activity
At12D1_00950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
At12D1_00960	COG0573	inorganic phosphate transmembrane transporter activity
At12D1_00980	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
At12D1_00990	COG0704	Plays a role in the regulation of phosphate uptake
At12D1_01000	COG0745	RESPONSE REGULATOR receiver
At12D1_01020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
At12D1_01030	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
At12D1_01040	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
At12D1_01050	COG2967	ApaG domain
At12D1_01070	COG0717	Belongs to the dCTP deaminase family
At12D1_01080	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
At12D1_01090	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
At12D1_01200	COG0167	dihydroorotate dehydrogenase activity
At12D1_01230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
At12D1_01270	COG1959	2 iron, 2 sulfur cluster binding
At12D1_01280	COG1201	RNA secondary structure unwinding
At12D1_01340	COG1960	acyl-CoA dehydrogenase activity
At12D1_01350	COG0183	Belongs to the thiolase family
At12D1_01360	COG1250	3-hydroxyacyl-CoA dehydrogenase
At12D1_01360	COG1024	Enoyl-CoA hydratase
At12D1_01390	COG1320	monovalent cation:proton antiporter activity
At12D1_01400	COG2212	antiporter activity
At12D1_01410	COG1863	multisubunit Na H antiporter MnhE subunit
At12D1_01420	COG0651	ATP synthesis coupled electron transport
At12D1_01430	COG1006	Multisubunit Na H antiporter MnhC subunit
At12D1_01440	COG2111	Na H antiporter
At12D1_01440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
At12D1_01460	COG0840	transmembrane signaling receptor activity
At12D1_01490	COG2198	Histidine kinase
At12D1_01490	COG0643	Histidine kinase
At12D1_01500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
At12D1_01510	COG2201	protein-glutamate methylesterase activity
At12D1_01520	COG0745	RESPONSE REGULATOR receiver
At12D1_01530	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
At12D1_01550	COG1766	The M ring may be actively involved in energy transduction
At12D1_01560	COG2771	luxR family
At12D1_01580	COG0840	transmembrane signaling receptor activity
At12D1_01580	COG2972	Histidine kinase
At12D1_01590	COG2205	protein histidine kinase activity
At12D1_01590	COG2198	Histidine kinase
At12D1_01590	COG0784	Response regulator, receiver
At12D1_01600	COG1970	mechanosensitive ion channel activity
At12D1_01610	COG0436	Aminotransferase
At12D1_01640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
At12D1_01650	COG0424	maF-like protein
At12D1_01660	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
At12D1_01680	COG5328	Belongs to the UPF0262 family
At12D1_01690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
At12D1_01710	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
At12D1_01740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
At12D1_01760	COG1338	Plays a role in the flagellum-specific transport system
At12D1_01780	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
At12D1_01800	COG1706	bacterial-type flagellum-dependent cell motility
At12D1_01810	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
At12D1_01820	COG4786	Flagellar basal body rod
At12D1_01830	COG1677	Flagellar hook-basal body complex protein FliE
At12D1_01840	COG1558	bacterial-type flagellum-dependent cell motility
At12D1_01850	COG1815	bacterial-type flagellum-dependent cell motility
At12D1_01870	COG1157	protein secretion by the type III secretion system
At12D1_01880	COG4786	Flagellar basal body rod
At12D1_01900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
At12D1_01910	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
At12D1_01920	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
At12D1_01930	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
At12D1_01940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
At12D1_01980	COG1360	Flagellar Motor Protein
At12D1_02030	COG1749	Flagellar hook protein flgE
At12D1_02070	COG5443	negative regulation of bacterial-type flagellum assembly
At12D1_02080	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
At12D1_02100	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
At12D1_02180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
At12D1_02190	COG1609	Transcriptional regulator
At12D1_02200	COG1653	transport
At12D1_02210	COG1175	transmembrane transport
At12D1_02220	COG0395	ABC-type sugar transport system, permease component
At12D1_02230	COG0366	Alpha amylase catalytic
At12D1_02240	COG3842	ATPase activity
At12D1_02270	COG0129	dihydroxy-acid dehydratase activity
At12D1_02280	COG0363	glucosamine-6-phosphate deaminase activity
At12D1_02290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
At12D1_02310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_02330	COG2081	HI0933 family
At12D1_02370	COG2224	Isocitrate lyase
At12D1_02400	COG3842	ATPase activity
At12D1_02410	COG1176	ABC-type spermidine putrescine transport system, permease component I
At12D1_02420	COG1177	transmembrane transport
At12D1_02440	COG2205	protein histidine kinase activity
At12D1_02450	COG0248	Ppx GppA phosphatase
At12D1_02460	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
At12D1_02470	COG0477	Major facilitator Superfamily
At12D1_02530	COG0521	Mo-molybdopterin cofactor biosynthetic process
At12D1_02540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
At12D1_02560	COG0142	geranyltranstransferase activity
At12D1_02610	COG0752	glycyl-tRNA synthetase alpha subunit
At12D1_02630	COG1704	LemA family
At12D1_02640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
At12D1_02660	COG0751	glycine-tRNA ligase activity
At12D1_02670	COG1683	Conserved Protein
At12D1_02680	COG0840	transmembrane signaling receptor activity
At12D1_02700	COG0151	Belongs to the GarS family
At12D1_02710	COG2183	response to ionizing radiation
At12D1_02720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
At12D1_02770	COG0583	DNA-binding transcription factor activity
At12D1_02810	COG0306	phosphate transporter
At12D1_02830	COG0561	phosphatase activity
At12D1_02840	COG0438	transferase activity, transferring glycosyl groups
At12D1_02850	COG2186	Transcriptional regulator
At12D1_02870	COG0583	DNA-binding transcription factor activity
At12D1_02880	COG0277	FAD linked oxidase domain protein
At12D1_02890	COG0277	FAD linked oxidase domain protein
At12D1_02900	COG0247	lactate metabolic process
At12D1_02920	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_02930	COG2818	Glycosylase
At12D1_02950	COG2855	membrane
At12D1_02960	COG0583	DNA-binding transcription factor activity
At12D1_03020	COG0124	histidyl-tRNA synthetase
At12D1_03040	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
At12D1_03050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
At12D1_03060	COG2259	Doxx family
At12D1_03080	COG0459	protein refolding
At12D1_03090	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
At12D1_03110	COG0196	riboflavin kinase activity
At12D1_03120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
At12D1_03140	COG0590	tRNA wobble adenosine to inosine editing
At12D1_03150	COG1187	pseudouridine synthase activity
At12D1_03160	COG0742	ribosomal rna small subunit methyltransferase
At12D1_03170	COG1752	Esterase of the alpha-beta hydrolase superfamily
At12D1_03190	COG0312	modulator of DNA gyrase
At12D1_03200	COG0483	inositol monophosphate 1-phosphatase activity
At12D1_03220	COG1519	Transferase
At12D1_03240	COG1663	tetraacyldisaccharide 4'-kinase activity
At12D1_03260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
At12D1_03270	COG0745	RESPONSE REGULATOR receiver
At12D1_03280	COG3300	MHYT domain
At12D1_03280	COG5001	Diguanylate cyclase
At12D1_03290	COG3386	PFAM SMP-30 Gluconolaconase
At12D1_03300	COG0800	Aldolase
At12D1_03310	COG3734	2-keto-3-deoxy-galactonokinase
At12D1_03320	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_03330	COG1414	Transcriptional regulator
At12D1_03340	COG2197	response regulator
At12D1_03370	COG0598	Magnesium transport protein CorA
At12D1_03380	COG3158	transport of potassium into the cell
At12D1_03410	COG0356	it plays a direct role in the translocation of protons across the membrane
At12D1_03430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
At12D1_03440	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
At12D1_03470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
At12D1_03510	COG0009	L-threonylcarbamoyladenylate synthase
At12D1_03530	COG4638	Rieske (2fe-2S)
At12D1_03580	COG1960	acyl-CoA dehydrogenase activity
At12D1_03610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
At12D1_03620	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
At12D1_03630	COG0840	transmembrane signaling receptor activity
At12D1_03650	COG1522	sequence-specific DNA binding
At12D1_03700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
At12D1_03710	COG1741	Belongs to the pirin family
At12D1_03720	COG1722	exodeoxyribonuclease VII activity
At12D1_03730	COG0123	including yeast histone deacetylase and acetoin utilization protein
At12D1_03740	COG1268	BioY protein
At12D1_03750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
At12D1_03760	COG1122	ATPase activity
At12D1_03770	COG3214	Protein conserved in bacteria
At12D1_03790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
At12D1_03820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
At12D1_03850	COG0259	pyridoxamine-phosphate oxidase activity
At12D1_03890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
At12D1_03910	COG0312	modulator of DNA gyrase
At12D1_03940	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
At12D1_03950	COG0109	protoheme IX farnesyltransferase activity
At12D1_03970	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
At12D1_04000	COG3346	SURF1 family
At12D1_04010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
At12D1_04020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
At12D1_04030	COG0328	RNA-DNA hybrid ribonuclease activity
At12D1_04050	COG0678	peroxiredoxin activity
At12D1_04050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
At12D1_04070	COG1678	Uncharacterized ACR, COG1678
At12D1_04080	COG3237	CsbD-like
At12D1_04100	COG5001	Diguanylate cyclase
At12D1_04100	COG3300	MHYT domain
At12D1_04110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
At12D1_04120	COG0612	Peptidase, M16
At12D1_04170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
At12D1_04180	COG1802	Transcriptional regulator
At12D1_04210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
At12D1_04220	COG3609	addiction module antidote protein, CC2985 family
At12D1_04230	COG3668	Plasmid stabilization system
At12D1_04250	COG1194	a g-specific adenine glycosylase
At12D1_04280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
At12D1_04290	COG1196	nuclear chromosome segregation
At12D1_04300	COG2514	catechol 2,3-dioxygenase activity
At12D1_04310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
At12D1_04310	COG0574	Belongs to the PEP-utilizing enzyme family
At12D1_04400	COG1846	Transcriptional regulator
At12D1_04410	COG2807	transmembrane transport
At12D1_04420	COG2211	Major facilitator Superfamily
At12D1_04450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
At12D1_04460	COG2814	Major facilitator Superfamily
At12D1_04480	COG0583	DNA-binding transcription factor activity
At12D1_04590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_04610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
At12D1_04620	COG5290	Psort location Cytoplasmic, score
At12D1_04730	COG0579	oxidoreductase
At12D1_04750	COG2895	sulfate adenylyltransferase (ATP) activity
At12D1_04760	COG0175	sulfate reduction
At12D1_04770	COG0175	sulfate reduction
At12D1_04780	COG1959	2 iron, 2 sulfur cluster binding
At12D1_04790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
At12D1_04800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
At12D1_04810	COG4208	sulfate ABC transporter
At12D1_04820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
At12D1_04840	COG2200	EAL domain
At12D1_04840	COG2203	Gaf domain
At12D1_04840	COG2199	diguanylate cyclase activity
At12D1_04860	COG1309	transcriptional regulator
At12D1_04870	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_04880	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
At12D1_04940	COG0625	glutathione transferase activity
At12D1_04960	COG0477	Major facilitator Superfamily
At12D1_04980	COG3657	addiction module killer protein
At12D1_05000	COG1793	dna ligase
At12D1_05000	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
At12D1_05040	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_05050	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_05060	COG1846	Transcriptional regulator
At12D1_05070	COG1764	response to oxidative stress
At12D1_05100	COG0488	(ABC) transporter
At12D1_05170	COG4221	oxidoreductase activity
At12D1_05200	COG0433	COG0433 Predicted ATPase
At12D1_05220	COG1733	regulation of RNA biosynthetic process
At12D1_05230	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
At12D1_05260	COG0656	L-ascorbic acid biosynthetic process
At12D1_05270	COG3781	membrane
At12D1_05280	COG2378	regulation of single-species biofilm formation
At12D1_05300	COG4106	trans-aconitate 2-methyltransferase activity
At12D1_05310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
At12D1_05320	COG0840	transmembrane signaling receptor activity
At12D1_05360	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
At12D1_05400	COG3909	cytochrome
At12D1_05410	COG2010	Cytochrome c
At12D1_05470	COG0789	Transcriptional regulator
At12D1_05520	COG0517	IMP dehydrogenase activity
At12D1_05520	COG4175	Glycine betaine
At12D1_05530	COG4176	ABC-type proline glycine betaine transport system permease component
At12D1_05590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
At12D1_05590	COG2169	Transcriptional regulator
At12D1_05610	COG2514	catechol 2,3-dioxygenase activity
At12D1_05640	COG1272	protein, Hemolysin III
At12D1_05660	COG1280	lysine exporter protein (LysE YggA)
At12D1_05670	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
At12D1_05690	COG2111	Na H antiporter
At12D1_05700	COG1006	Multisubunit Na H antiporter MnhC subunit
At12D1_05730	COG2212	antiporter activity
At12D1_05740	COG1320	monovalent cation:proton antiporter activity
At12D1_05750	COG4957	zinc ion binding
At12D1_05780	COG2166	iron-sulfur cluster assembly
At12D1_05800	COG2205	protein histidine kinase activity
At12D1_05910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At12D1_05920	COG2983	Belongs to the UPF0260 family
At12D1_05940	COG3041	Addiction module toxin RelE StbE family
At12D1_05950	COG3077	Addiction module antitoxin, RelB DinJ family
At12D1_05960	COG2217	Heavy metal translocating P-type atpase
At12D1_06020	COG2814	Major facilitator Superfamily
At12D1_06040	COG1621	beta-fructofuranosidase activity
At12D1_06050	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
At12D1_06160	COG4695	Portal protein
At12D1_06340	COG0745	RESPONSE REGULATOR receiver
At12D1_06350	COG5002	protein histidine kinase activity
At12D1_06370	COG4235	cytochrome complex assembly
At12D1_06380	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
At12D1_06390	COG1138	Cytochrome C-type biogenesis protein
At12D1_06400	COG3088	subunit of a heme lyase
At12D1_06410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
At12D1_06420	COG0745	RESPONSE REGULATOR receiver
At12D1_06440	COG3011	Protein conserved in bacteria
At12D1_06450	COG3713	MltA-interacting MipA family protein
At12D1_06460	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
At12D1_06470	COG2205	protein histidine kinase activity
At12D1_06470	COG2202	Pas domain
At12D1_06490	COG0308	aminopeptidase N
At12D1_06510	COG2433	Pfam Transposase IS66
At12D1_06520	COG3436	PFAM IS66 Orf2 family protein
At12D1_06530	COG2963	transposase activity
At12D1_06550	COG0697	spore germination
At12D1_06580	COG0443	Heat shock 70 kDa protein
At12D1_06600	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_06650	COG0604	alcohol dehydrogenase
At12D1_06660	COG1733	regulation of RNA biosynthetic process
At12D1_06670	COG1968	undecaprenyl-diphosphatase activity
At12D1_06680	COG2239	Acts as a magnesium transporter
At12D1_06690	COG2814	Major facilitator Superfamily
At12D1_06740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
At12D1_06800	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
At12D1_06880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
At12D1_06890	COG0741	lytic transglycosylase activity
At12D1_06900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_06910	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
At12D1_06920	COG0840	transmembrane signaling receptor activity
At12D1_06940	COG1758	RNA polymerase activity
At12D1_06980	COG0736	holo-[acyl-carrier-protein] synthase activity
At12D1_06990	COG0681	Belongs to the peptidase S26 family
At12D1_07000	COG0571	ribonuclease III activity
At12D1_07010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
At12D1_07030	COG0784	Response regulator, receiver
At12D1_07040	COG1381	Involved in DNA repair and RecF pathway recombination
At12D1_07060	COG2226	methyltransferase
At12D1_07080	COG1418	mRNA catabolic process
At12D1_07100	COG0346	lactoylglutathione lyase activity
At12D1_07130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_07140	COG3443	Belongs to the bacterial solute-binding protein 9 family
At12D1_07150	COG0668	transmembrane transport
At12D1_07170	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
At12D1_07230	COG1742	UPF0060 membrane protein
At12D1_07250	COG3706	GGDEF domain
At12D1_07250	COG0745	RESPONSE REGULATOR receiver
At12D1_07270	COG1183	phosphatidylcholine synthase activity
At12D1_07280	COG0688	phosphatidylethanolamine metabolic process
At12D1_07290	COG5265	(ABC) transporter
At12D1_07370	COG2852	Protein conserved in bacteria
At12D1_07380	COG0215	cysteine-tRNA ligase activity
At12D1_07390	COG4221	oxidoreductase activity
At12D1_07400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
At12D1_07410	COG1286	toxin biosynthetic process
At12D1_07450	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
At12D1_07470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
At12D1_07490	COG0305	Participates in initiation and elongation during chromosome replication
At12D1_07530	COG0359	binds to the 23S rRNA
At12D1_07550	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
At12D1_07560	COG0360	Binds together with S18 to 16S ribosomal RNA
At12D1_07580	COG0667	Aldo Keto reductase
At12D1_07590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
At12D1_07610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At12D1_07620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
At12D1_07640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
At12D1_07650	COG1561	YicC-like family, N-terminal region
At12D1_07660	COG0194	GDP metabolic process
At12D1_07690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
At12D1_07700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
At12D1_07720	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
At12D1_07750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
At12D1_07790	COG4251	negative regulation of phosphorylation
At12D1_07790	COG5001	Diguanylate cyclase
At12D1_07790	COG2203	Gaf domain
At12D1_07790	COG3706	GGDEF domain
At12D1_07800	COG3300	MHYT domain
At12D1_07800	COG5001	Diguanylate cyclase
At12D1_07810	COG4191	Histidine kinase
At12D1_07820	COG4566	intracellular signal transduction
At12D1_07840	COG0488	(ABC) transporter
At12D1_07850	COG3706	GGDEF domain
At12D1_07870	COG0105	UTP biosynthetic process
At12D1_07910	COG0314	molybdopterin synthase activity
At12D1_07930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
At12D1_07940	COG0322	excinuclease ABC activity
At12D1_07950	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_08000	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
At12D1_08010	COG0243	molybdopterin cofactor binding
At12D1_08060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
At12D1_08070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
At12D1_08090	COG0628	permease
At12D1_08110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
At12D1_08120	COG0248	Ppx GppA phosphatase
At12D1_08170	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
At12D1_08190	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
At12D1_08200	COG0477	Major facilitator Superfamily
At12D1_08210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
At12D1_08230	COG0840	transmembrane signaling receptor activity
At12D1_08240	COG0659	secondary active sulfate transmembrane transporter activity
At12D1_08260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
At12D1_08270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
At12D1_08290	COG0113	porphobilinogen synthase activity
At12D1_08330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
At12D1_08340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
At12D1_08350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
At12D1_08350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
At12D1_08370	COG1280	lysine exporter protein (LysE YggA)
At12D1_08380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
At12D1_08390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
At12D1_08400	COG2814	Major facilitator Superfamily
At12D1_08410	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
At12D1_08450	COG0416	fatty acid biosynthetic process
At12D1_08460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
At12D1_08470	COG0776	regulation of translation
At12D1_08530	COG0601	transmembrane transport
At12D1_08540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_08550	COG0444	Belongs to the ABC transporter superfamily
At12D1_08570	COG0747	negative chemotaxis
At12D1_08590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
At12D1_08600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
At12D1_08620	COG0745	RESPONSE REGULATOR receiver
At12D1_08620	COG3706	GGDEF domain
At12D1_08630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
At12D1_08640	COG0583	DNA-binding transcription factor activity
At12D1_08650	COG0737	Belongs to the 5'-nucleotidase family
At12D1_08690	COG2897	thiosulfate sulfurtransferase activity
At12D1_08720	COG0415	Belongs to the DNA photolyase family
At12D1_08740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
At12D1_08790	COG3932	Exopolysaccharide synthesis, ExoD
At12D1_08810	COG1238	metal cluster binding
At12D1_08950	COG1612	heme a metabolic process
At12D1_08970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
At12D1_08980	COG0010	Belongs to the arginase family
At12D1_08990	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
At12D1_09000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
At12D1_09020	COG1832	CoA-binding protein
At12D1_09070	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_09080	COG2124	cytochrome p450
At12D1_09090	COG2199	diguanylate cyclase activity
At12D1_09100	COG0740	serine-type endopeptidase activity
At12D1_09110	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
At12D1_09130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
At12D1_09150	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
At12D1_09160	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At12D1_09170	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At12D1_09180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At12D1_09200	COG0649	NAD binding
At12D1_09220	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
At12D1_09230	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
At12D1_09250	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
At12D1_09260	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
At12D1_09280	COG0713	ATP synthesis coupled electron transport
At12D1_09310	COG1007	ATP synthesis coupled electron transport
At12D1_09320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
At12D1_09320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
At12D1_09350	COG0442	prolyl-tRNA aminoacylation
At12D1_09370	COG1136	(ABC) transporter
At12D1_09380	COG0587	DNA-directed DNA polymerase activity
At12D1_09400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
At12D1_09440	COG0784	Response regulator, receiver
At12D1_09450	COG0745	RESPONSE REGULATOR receiver
At12D1_09450	COG3706	GGDEF domain
At12D1_09460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
At12D1_09470	COG0477	Major facilitator Superfamily
At12D1_09500	COG0557	exoribonuclease II activity
At12D1_09510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
At12D1_09530	COG0758	DNA mediated transformation
At12D1_09540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
At12D1_09560	COG0540	Belongs to the ATCase OTCase family
At12D1_09590	COG1960	acyl-CoA dehydrogenase activity
At12D1_09600	COG0456	acetyltransferase
At12D1_09640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
At12D1_09650	COG2824	Alkylphosphonate utilization operon protein PhnA
At12D1_09660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
At12D1_09670	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
At12D1_09680	COG0154	amidase activity
At12D1_09690	COG0456	acetyltransferase
At12D1_09700	COG3811	Belongs to the UPF0386 family
At12D1_09730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
At12D1_09750	COG0456	acetyltransferase
At12D1_09790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
At12D1_09800	COG0439	Biotin carboxylase
At12D1_09810	COG0511	ligase activity, forming carbon-carbon bonds
At12D1_09820	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
At12D1_09840	COG0436	Aminotransferase
At12D1_09880	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_09890	COG1530	ribonuclease E activity
At12D1_09910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At12D1_09950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
At12D1_09960	COG0384	phenazine biosynthesis protein PhzF
At12D1_10010	COG0633	Ferredoxin
At12D1_10040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
At12D1_10050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
At12D1_10070	COG3768	UPF0283 membrane protein
At12D1_10080	COG3106	COG3106 Predicted ATPase
At12D1_10100	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
At12D1_10140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
At12D1_10210	COG0537	adenosine 5'-monophosphoramidase activity
At12D1_10260	COG0052	Belongs to the universal ribosomal protein uS2 family
At12D1_10270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
At12D1_10280	COG0528	UMP kinase activity
At12D1_10290	COG0233	cytoplasmic translational termination
At12D1_10300	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
At12D1_10310	COG0575	Belongs to the CDS family
At12D1_10320	COG0750	zinc metalloprotease
At12D1_10330	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
At12D1_10340	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
At12D1_10350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
At12D1_10360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
At12D1_10370	COG3494	Protein of unknown function (DUF1009)
At12D1_10380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
At12D1_10390	COG2186	Transcriptional regulator
At12D1_10410	COG0765	amino acid transport
At12D1_10440	COG0372	Belongs to the citrate synthase family
At12D1_10470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
At12D1_10490	COG2877	3-deoxy-8-phosphooctulonate synthase activity
At12D1_10500	COG0148	phosphopyruvate hydratase activity
At12D1_10520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
At12D1_10530	COG0022	dehydrogenase e1 component
At12D1_10530	COG0508	dehydrogenase complex catalyzes the overall conversion of
At12D1_10540	COG0508	dehydrogenase complex catalyzes the overall conversion of
At12D1_10560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
At12D1_10580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
At12D1_10590	COG0697	spore germination
At12D1_10630	COG2867	negative regulation of translational initiation
At12D1_10640	COG1058	Belongs to the CinA family
At12D1_10640	COG1546	Belongs to the CinA family
At12D1_10650	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
At12D1_10650	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
At12D1_10670	COG3852	Histidine kinase
At12D1_10680	COG2204	response regulator
At12D1_10690	COG5000	phosphorelay sensor kinase activity
At12D1_10700	COG2204	response regulator
At12D1_10710	COG0569	domain protein
At12D1_10720	COG1923	regulation of RNA biosynthetic process
At12D1_10730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
At12D1_10740	COG3956	TIGRFAM MazG family protein
At12D1_10760	COG1648	precorrin-2 dehydrogenase activity
At12D1_10760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
At12D1_10840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
At12D1_10840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
At12D1_10850	COG0509	glycine decarboxylation via glycine cleavage system
At12D1_10860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At12D1_10910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
At12D1_10920	COG0564	pseudouridine synthase activity
At12D1_10960	COG0251	oxidation-reduction process
At12D1_10970	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
At12D1_10990	COG1671	Belongs to the UPF0178 family
At12D1_11020	COG0450	alkyl hydroperoxide reductase
At12D1_11030	COG0625	glutathione transferase activity
At12D1_11050	COG2801	Transposase and inactivated derivatives
At12D1_11060	COG0431	NADPH-dependent FMN reductase
At12D1_11080	COG0798	PFAM Bile acid sodium symporter
At12D1_11090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
At12D1_11120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
At12D1_11120	COG0321	lipoyl(octanoyl) transferase activity
At12D1_11130	COG0084	hydrolase, TatD family'
At12D1_11140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
At12D1_11160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
At12D1_11260	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
At12D1_11270	COG2095	MarC family integral membrane protein
At12D1_11280	COG2239	Acts as a magnesium transporter
At12D1_11300	COG0629	single-stranded DNA binding
At12D1_11310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
At12D1_11330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
At12D1_11370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
At12D1_11380	COG1121	(ABC) transporter
At12D1_11390	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
At12D1_11420	COG0667	Aldo Keto reductase
At12D1_11570	COG1396	sequence-specific DNA binding
At12D1_11660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
At12D1_11720	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
At12D1_11880	COG2239	Acts as a magnesium transporter
At12D1_11890	COG0243	molybdopterin cofactor binding
At12D1_11910	COG0242	peptide deformylase activity
At12D1_11940	COG2202	Pas domain
At12D1_11940	COG2205	protein histidine kinase activity
At12D1_11960	COG0321	lipoyl(octanoyl) transferase activity
At12D1_11970	COG1064	alcohol dehydrogenase
At12D1_12070	COG2124	cytochrome p450
At12D1_12130	COG0626	cystathionine gamma-synthase activity
At12D1_12140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_12150	COG4597	amino acid ABC transporter
At12D1_12160	COG0765	amino acid transport
At12D1_12170	COG1126	abc transporter atp-binding protein
At12D1_12180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
At12D1_12210	COG0436	Aminotransferase
At12D1_12270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
At12D1_12290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
At12D1_12300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At12D1_12310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
At12D1_12340	COG3243	poly(R)-hydroxyalkanoic acid synthase
At12D1_12350	COG1489	DNA binding
At12D1_12360	COG0024	Methionine aminopeptidase
At12D1_12370	COG2003	Belongs to the UPF0758 family
At12D1_12400	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
At12D1_12450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
At12D1_12460	COG0546	phosphoglycolate phosphatase activity
At12D1_12480	COG0114	fumarate hydratase activity
At12D1_12500	COG0504	CTP synthase activity
At12D1_12520	COG0149	triose-phosphate isomerase activity
At12D1_12540	COG0187	DNA topoisomerase II activity
At12D1_12560	COG0740	serine-type endopeptidase activity
At12D1_12580	COG0640	Transcriptional regulator
At12D1_12590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
At12D1_12650	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
At12D1_12650	COG3264	Mechanosensitive ion channel
At12D1_12770	COG1127	ABC transporter
At12D1_12780	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
At12D1_12790	COG4948	Mandelate Racemase Muconate Lactonizing
At12D1_12810	COG0280	phosphate acetyltransferase
At12D1_12810	COG0281	malic enzyme
At12D1_12830	COG0778	Nitroreductase
At12D1_12840	COG0823	Involved in the tonB-independent uptake of proteins
At12D1_12870	COG1368	sulfuric ester hydrolase activity
At12D1_12910	COG3265	gluconokinase activity
At12D1_12920	COG0544	peptidyl-prolyl cis-trans isomerase activity
At12D1_12950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
At12D1_12990	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
At12D1_13020	COG0318	PFAM AMP-dependent synthetase and ligase
At12D1_13040	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
At12D1_13040	COG0512	Glutamine amidotransferase of anthranilate synthase
At12D1_13050	COG0343	queuine tRNA-ribosyltransferase activity
At12D1_13060	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
At12D1_13070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
At12D1_13080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
At12D1_13090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
At12D1_13130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
At12D1_13140	COG0134	indole-3-glycerol-phosphate synthase activity
At12D1_13150	COG0315	cyclic pyranopterin monophosphate synthase activity
At12D1_13160	COG0303	'Molybdopterin
At12D1_13170	COG3706	GGDEF domain
At12D1_13190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
At12D1_13190	COG0475	glutathione-regulated potassium exporter activity
At12D1_13210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
At12D1_13230	COG2814	Major facilitator Superfamily
At12D1_13240	COG0746	molybdenum cofactor guanylyltransferase activity
At12D1_13250	COG1763	Mo-molybdopterin cofactor biosynthetic process
At12D1_13260	COG0739	heme binding
At12D1_13270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
At12D1_13280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
At12D1_13290	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
At12D1_13300	COG0805	protein transport
At12D1_13310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
At12D1_13320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
At12D1_13330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
At12D1_13340	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
At12D1_13350	COG1472	Belongs to the glycosyl hydrolase 3 family
At12D1_13370	COG0018	arginyl-trna synthetase
At12D1_13380	COG0232	Belongs to the dGTPase family. Type 2 subfamily
At12D1_13430	COG0525	valine-tRNA ligase activity
At12D1_13450	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
At12D1_13540	COG0655	NAD(P)H dehydrogenase (quinone) activity
At12D1_13550	COG1058	Belongs to the CinA family
At12D1_13550	COG1546	Belongs to the CinA family
At12D1_13560	COG0589	response to stress
At12D1_13570	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
At12D1_13580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
At12D1_13670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
At12D1_13700	COG2801	Transposase and inactivated derivatives
At12D1_13720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
At12D1_13800	COG0640	Transcriptional regulator
At12D1_13810	COG1914	H( )-stimulated, divalent metal cation uptake system
At12D1_13830	COG1132	(ABC) transporter
At12D1_13840	COG0628	permease
At12D1_13910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
At12D1_13930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
At12D1_13950	COG0302	gtp cyclohydrolase
At12D1_13960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
At12D1_13970	COG1752	Esterase of the alpha-beta hydrolase superfamily
At12D1_13990	COG0517	IMP dehydrogenase activity
At12D1_13990	COG0516	GMP reductase activity
At12D1_14050	COG1760	l-serine dehydratase
At12D1_14120	COG0583	DNA-binding transcription factor activity
At12D1_14150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
At12D1_14150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
At12D1_14160	COG0347	Belongs to the P(II) protein family
At12D1_14170	COG0174	glutamine synthetase
At12D1_14200	COG3293	Transposase
At12D1_14250	COG0697	spore germination
At12D1_14270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
At12D1_14290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
At12D1_14350	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
At12D1_14360	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
At12D1_14370	COG2186	Transcriptional regulator
At12D1_14410	COG1129	ABC transporter
At12D1_14420	COG1183	phosphatidylcholine synthase activity
At12D1_14430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
At12D1_14440	COG0679	Auxin Efflux Carrier
At12D1_14450	COG0785	Cytochrome C biogenesis protein
At12D1_14480	COG1278	Cold shock
At12D1_14570	COG0577	efflux transmembrane transporter activity
At12D1_14570	COG1136	(ABC) transporter
At12D1_14580	COG0577	efflux transmembrane transporter activity
At12D1_14580	COG1136	(ABC) transporter
At12D1_14630	COG2151	metal-sulfur cluster biosynthetic enzyme
At12D1_14640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
At12D1_14650	COG0719	Fe-S assembly protein
At12D1_14660	COG0396	ATPase activity
At12D1_14670	COG0719	Fe-S assembly protein
At12D1_14680	COG1104	cysteine desulfurase activity
At12D1_14690	COG2945	thiolester hydrolase activity
At12D1_14700	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
At12D1_14710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
At12D1_14730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
At12D1_14740	COG2833	Protein of unknown function (DUF455)
At12D1_14750	COG0739	heme binding
At12D1_14760	COG0513	Belongs to the DEAD box helicase family
At12D1_14810	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
At12D1_14830	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
At12D1_14840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
At12D1_14850	COG0047	phosphoribosylformylglycinamidine synthase activity
At12D1_14880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At12D1_14890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
At12D1_14940	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
At12D1_14950	COG2814	Major facilitator Superfamily
At12D1_14960	COG0483	inositol monophosphate 1-phosphatase activity
At12D1_14970	COG0483	inositol monophosphate 1-phosphatase activity
At12D1_14980	COG0037	tRNA processing
At12D1_14990	COG2066	Belongs to the glutaminase family
At12D1_15000	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
At12D1_15010	COG0861	Integral membrane protein TerC family
At12D1_15040	COG1280	lysine exporter protein (LysE YggA)
At12D1_15070	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
At12D1_15080	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
At12D1_15100	COG0538	isocitrate dehydrogenase activity
At12D1_15120	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
At12D1_15130	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
At12D1_15140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_15150	COG2313	pseudouridylate synthase activity
At12D1_15170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_15180	COG4215	(ABC) transporter
At12D1_15200	COG5425	PFAM Usg family protein
At12D1_15220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_15230	COG1522	sequence-specific DNA binding
At12D1_15240	COG1573	uracil-dna glycosylase
At12D1_15260	COG2205	protein histidine kinase activity
At12D1_15260	COG2202	Pas domain
At12D1_15270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
At12D1_15280	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
At12D1_15290	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
At12D1_15320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
At12D1_15330	COG0842	Transport permease protein
At12D1_15340	COG1131	(ABC) transporter
At12D1_15380	COG0840	transmembrane signaling receptor activity
At12D1_15400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
At12D1_15410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
At12D1_15450	COG0129	dihydroxy-acid dehydratase activity
At12D1_15460	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
At12D1_15470	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
At12D1_15490	COG3739	integral membrane protein
At12D1_15500	COG0203	ribosomal protein L17
At12D1_15510	COG0202	RNA polymerase activity
At12D1_15520	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
At12D1_15530	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
At12D1_15540	COG0563	adenylate kinase activity
At12D1_15550	COG0201	protein transport
At12D1_15560	COG0200	Binds to the 23S rRNA
At12D1_15570	COG1841	ribosomal large subunit assembly
At12D1_15580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
At12D1_15590	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
At12D1_15600	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
At12D1_15610	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
At12D1_15620	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
At12D1_15630	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
At12D1_15640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
At12D1_15650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
At12D1_15660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
At12D1_15670	COG0255	Belongs to the universal ribosomal protein uL29 family
At12D1_15680	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
At12D1_15690	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
At12D1_15700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
At12D1_15710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
At12D1_15720	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
At12D1_15730	COG0089	rRNA binding
At12D1_15740	COG0088	Forms part of the polypeptide exit tunnel
At12D1_15750	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
At12D1_15760	COG0051	transcription antitermination factor activity, RNA binding
At12D1_15770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
At12D1_15780	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
At12D1_15790	COG0049	tRNA binding
At12D1_15800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
At12D1_15840	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
At12D1_15850	COG0085	RNA polymerase activity
At12D1_15860	COG0222	ribosome binding
At12D1_15870	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
At12D1_15880	COG0081	regulation of translation
At12D1_15890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
At12D1_15920	COG1086	Polysaccharide biosynthesis protein
At12D1_15930	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
At12D1_15940	COG0861	Integral membrane protein TerC family
At12D1_15990	COG1132	(ABC) transporter
At12D1_16000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
At12D1_16040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
At12D1_16110	COG0784	Response regulator, receiver
At12D1_16110	COG2198	Histidine kinase
At12D1_16110	COG2205	protein histidine kinase activity
At12D1_16110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_16120	COG0784	Response regulator, receiver
At12D1_16130	COG2202	Pas domain
At12D1_16130	COG3920	Histidine kinase
At12D1_16140	COG0784	Response regulator, receiver
At12D1_16150	COG4251	negative regulation of phosphorylation
At12D1_16160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
At12D1_16170	COG1607	acyl-coa hydrolase
At12D1_16210	COG2910	NAD(P)H-binding
At12D1_16220	COG1733	regulation of RNA biosynthetic process
At12D1_16250	COG0556	nucleotide-excision repair
At12D1_16270	COG2382	esterase
At12D1_16310	COG0484	heat shock protein binding
At12D1_16350	COG3706	GGDEF domain
At12D1_16390	COG1840	ABC-type Fe3 transport system, periplasmic component
At12D1_16400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At12D1_16410	COG4154	Belongs to the RbsD FucU family
At12D1_16430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
At12D1_16450	COG2207	Transcriptional regulator
At12D1_16460	COG1064	alcohol dehydrogenase
At12D1_16470	COG1252	NADH dehydrogenase
At12D1_16480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
At12D1_16490	COG2197	response regulator
At12D1_16500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
At12D1_16570	COG0656	L-ascorbic acid biosynthetic process
At12D1_16600	COG0440	acetolactate synthase activity
At12D1_16610	COG0028	Belongs to the TPP enzyme family
At12D1_16630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
At12D1_16640	COG0560	Phosphoserine phosphatase
At12D1_16640	COG3830	Belongs to the UPF0237 family
At12D1_16680	COG0330	HflC and HflK could
At12D1_16690	COG0330	HflC and HflK could
At12D1_16710	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
At12D1_16770	COG0277	FAD linked oxidase domain protein
At12D1_16780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At12D1_16860	COG1335	isochorismatase
At12D1_16920	COG2264	protein methyltransferase activity
At12D1_16930	COG1999	signal sequence binding
At12D1_16950	COG0835	chemotaxis
At12D1_16970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
At12D1_16980	COG0583	DNA-binding transcription factor activity
At12D1_17000	COG1247	-acetyltransferase
At12D1_17020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
At12D1_17030	COG0497	DNA recombination
At12D1_17040	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
At12D1_17060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
At12D1_17070	COG0849	cell division
At12D1_17080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
At12D1_17090	COG1181	Belongs to the D-alanine--D-alanine ligase family
At12D1_17100	COG0477	Major facilitator Superfamily
At12D1_17110	COG5001	Diguanylate cyclase
At12D1_17120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
At12D1_17130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
At12D1_17140	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
At12D1_17160	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
At12D1_17170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
At12D1_17190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
At12D1_17220	COG0275	rRNA processing
At12D1_17230	COG2001	Belongs to the MraZ family
At12D1_17240	COG3766	membrane
At12D1_17260	COG0754	glutathionylspermidine amidase activity
At12D1_17300	COG3023	N-Acetylmuramoyl-L-alanine amidase
At12D1_17310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
At12D1_17360	COG4106	trans-aconitate 2-methyltransferase activity
At12D1_17420	COG2267	carboxylic ester hydrolase activity
At12D1_17430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
At12D1_17460	COG0251	oxidation-reduction process
At12D1_17490	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_17500	COG2814	Major facilitator Superfamily
At12D1_17570	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_17580	COG0174	glutamine synthetase
At12D1_17590	COG0531	amino acid
At12D1_17610	COG1737	Transcriptional regulator
At12D1_17620	COG2182	Extracellular solute-binding protein
At12D1_17650	COG3842	ATPase activity
At12D1_17760	COG2968	Membrane
At12D1_17780	COG0432	Pfam Uncharacterised protein family UPF0047
At12D1_17810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
At12D1_17820	COG0358	DNA primase activity
At12D1_17850	COG0505	Belongs to the CarA family
At12D1_17860	COG0534	Mate efflux family protein
At12D1_17890	COG2321	neutral zinc metallopeptidase
At12D1_17920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
At12D1_17940	COG3706	GGDEF domain
At12D1_17970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
At12D1_17990	COG1522	sequence-specific DNA binding
At12D1_18000	COG0492	ferredoxin-NADP+ reductase activity
At12D1_18010	COG0583	DNA-binding transcription factor activity
At12D1_18030	COG1902	pentaerythritol trinitrate reductase activity
At12D1_18080	COG0387	Pfam Sodium calcium exchanger
At12D1_18100	COG2200	EAL domain
At12D1_18100	COG2199	diguanylate cyclase activity
At12D1_18130	COG1278	Cold shock
At12D1_18140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
At12D1_18160	COG1846	Transcriptional regulator
At12D1_18170	COG0745	RESPONSE REGULATOR receiver
At12D1_18180	COG2205	protein histidine kinase activity
At12D1_18190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
At12D1_18230	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
At12D1_18280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
At12D1_18300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
At12D1_18330	COG0840	transmembrane signaling receptor activity
At12D1_18340	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_18360	COG3300	MHYT domain
At12D1_18360	COG5001	Diguanylate cyclase
At12D1_18370	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
At12D1_18380	COG5001	Diguanylate cyclase
At12D1_18400	COG0193	aminoacyl-tRNA hydrolase activity
At12D1_18420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
At12D1_18470	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
At12D1_18490	COG2857	Cytochrome c1
At12D1_18490	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
At12D1_18530	COG1132	(ABC) transporter
At12D1_18540	COG1132	(ABC) transporter
At12D1_18560	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
At12D1_18590	COG0408	coproporphyrinogen oxidase activity
At12D1_18620	COG0617	tRNA 3'-terminal CCA addition
At12D1_18650	COG0714	Associated with various cellular activities
At12D1_18690	COG0454	-acetyltransferase
At12D1_18720	COG0477	Major facilitator Superfamily
At12D1_18740	COG0435	Glutathione S-transferase
At12D1_18750	COG0494	nUDIX hydrolase
At12D1_18770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
At12D1_18780	COG3135	benzoate transporter
At12D1_18830	COG0740	serine-type endopeptidase activity
At12D1_18860	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
At12D1_18870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
At12D1_18920	COG4175	Glycine betaine
At12D1_18950	COG1435	thymidine kinase activity
At12D1_19000	COG1629	transport
At12D1_19000	COG4771	TonB-dependent receptor
At12D1_19020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
At12D1_19020	COG0512	Glutamine amidotransferase of anthranilate synthase
At12D1_19050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
At12D1_19070	COG0366	Alpha amylase catalytic
At12D1_19080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_19120	COG1160	GTP binding
At12D1_19160	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
At12D1_19180	COG0024	Methionine aminopeptidase
At12D1_19200	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_19220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
At12D1_19250	COG0583	DNA-binding transcription factor activity
At12D1_19280	COG0402	S-adenosylhomocysteine deaminase activity
At12D1_19320	COG1309	transcriptional regulator
At12D1_19330	COG1686	Belongs to the peptidase S11 family
At12D1_19350	COG2351	hydroxyisourate hydrolase activity
At12D1_19360	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
At12D1_19410	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
At12D1_19430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_19430	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
At12D1_19450	COG0513	Belongs to the DEAD box helicase family
At12D1_19470	COG2259	Doxx family
At12D1_19480	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_19500	COG2308	Evidence 4 Homologs of previously reported genes of
At12D1_19520	COG1305	Transglutaminase-like
At12D1_19560	COG0588	phosphoglycerate mutase activity
At12D1_19580	COG4214	carbohydrate transport
At12D1_19600	COG4213	ABC transporter substrate-binding protein
At12D1_19800	COG3293	Transposase
At12D1_19820	COG0840	transmembrane signaling receptor activity
At12D1_19850	COG0646	methionine synthase
At12D1_19850	COG1410	methionine synthase
At12D1_19870	COG4215	(ABC) transporter
At12D1_19940	COG1215	transferase activity, transferring glycosyl groups
At12D1_19970	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
At12D1_20000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
At12D1_20030	COG2346	COG2346, Truncated hemoglobins
At12D1_20070	COG1309	transcriptional regulator
At12D1_20100	COG0494	nUDIX hydrolase
At12D1_20120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_20130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_20190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
At12D1_20200	COG0830	nickel cation binding
At12D1_20210	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
At12D1_20240	COG0804	urea catabolic process
At12D1_20250	COG1442	glycosyl transferase family 8
At12D1_20260	COG3755	Protein conserved in bacteria
At12D1_20280	COG0832	Belongs to the urease beta subunit family
At12D1_20290	COG3813	Protein conserved in bacteria
At12D1_20300	COG0831	urea catabolic process
At12D1_20310	COG0829	nickel cation binding
At12D1_20370	COG0559	Belongs to the binding-protein-dependent transport system permease family
At12D1_20400	COG0174	glutamine synthetase
At12D1_20410	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_20420	COG0784	Response regulator, receiver
At12D1_20420	COG2198	Histidine kinase
At12D1_20420	COG5002	protein histidine kinase activity
At12D1_20450	COG0726	polysaccharide deacetylase
At12D1_20490	COG0411	ABC transporter
At12D1_20520	COG1218	3'(2'),5'-bisphosphate nucleotidase
At12D1_20670	COG0564	pseudouridine synthase activity
At12D1_20690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
At12D1_20710	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
At12D1_20760	COG0346	lactoylglutathione lyase activity
At12D1_20780	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
At12D1_20800	COG2832	Protein of unknown function (DUF454)
At12D1_20810	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
At12D1_20820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_20830	COG4558	Periplasmic binding protein
At12D1_20850	COG3721	Heme iron utilization protein
At12D1_20880	COG3655	Transcriptional regulator
At12D1_20910	COG3657	addiction module killer protein
At12D1_20930	COG2205	protein histidine kinase activity
At12D1_21010	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_21020	COG4605	iron ion homeostasis
At12D1_21030	COG4604	ABC transporter, ATP-binding protein
At12D1_21040	COG0783	Belongs to the Dps family
At12D1_21060	COG2972	Histidine kinase
At12D1_21060	COG0840	transmembrane signaling receptor activity
At12D1_21070	COG0656	L-ascorbic acid biosynthetic process
At12D1_21080	COG2814	Major facilitator Superfamily
At12D1_21100	COG0583	DNA-binding transcription factor activity
At12D1_21120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_21160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
At12D1_21170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
At12D1_21180	COG0288	reversible hydration of carbon dioxide
At12D1_21200	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
At12D1_21230	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
At12D1_21240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At12D1_21250	COG0778	Nitroreductase
At12D1_21260	COG2267	carboxylic ester hydrolase activity
At12D1_21270	COG0251	oxidation-reduction process
At12D1_21280	COG1335	isochorismatase
At12D1_21290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_21310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_21340	COG1175	transmembrane transport
At12D1_21350	COG0395	ABC-type sugar transport system, permease component
At12D1_21360	COG3842	ATPase activity
At12D1_21370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_21390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
At12D1_21420	COG4608	Belongs to the ABC transporter superfamily
At12D1_21430	COG0444	Belongs to the ABC transporter superfamily
At12D1_21450	COG0601	transmembrane transport
At12D1_21560	COG2159	amidohydrolase
At12D1_21570	COG1960	acyl-CoA dehydrogenase activity
At12D1_21630	COG0745	RESPONSE REGULATOR receiver
At12D1_21650	COG0446	pyridine nucleotide-disulphide oxidoreductase
At12D1_21650	COG1902	pentaerythritol trinitrate reductase activity
At12D1_21660	COG3842	ATPase activity
At12D1_21680	COG1840	ABC-type Fe3 transport system, periplasmic component
At12D1_21690	COG1840	ABC-type Fe3 transport system, periplasmic component
At12D1_21700	COG0745	RESPONSE REGULATOR receiver
At12D1_21720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
At12D1_21730	COG0583	DNA-binding transcription factor activity
At12D1_21740	COG1278	Cold shock
At12D1_21770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_21780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_21840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At12D1_21890	COG2144	transferase activity, transferring acyl groups
At12D1_21900	COG0438	transferase activity, transferring glycosyl groups
At12D1_21920	COG2072	flavoprotein involved in K transport
At12D1_21940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
At12D1_21960	COG2814	Major facilitator Superfamily
At12D1_21970	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_22010	COG3485	protocatechuate 3,4-dioxygenase
At12D1_22080	COG0601	transmembrane transport
At12D1_22090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_22100	COG4172	Belongs to the ABC transporter superfamily
At12D1_22140	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_22170	COG4977	sequence-specific DNA binding
At12D1_22170	COG1917	Cupin 2, conserved barrel domain protein
At12D1_22180	COG4372	Transposase
At12D1_22280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_22300	COG1294	oxidase, subunit
At12D1_22310	COG1271	oxidase subunit
At12D1_22320	COG2801	Transposase and inactivated derivatives
At12D1_22340	COG1063	alcohol dehydrogenase
At12D1_22350	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_22360	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_22370	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_22380	COG1129	ABC transporter
At12D1_22390	COG1879	ABC-type sugar transport system periplasmic component
At12D1_22400	COG1609	Transcriptional regulator
At12D1_22410	COG3415	Transposase
At12D1_22430	COG3335	DDE superfamily endonuclease
At12D1_22440	COG1879	ABC-type sugar transport system periplasmic component
At12D1_22450	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_22460	COG1129	ABC transporter
At12D1_22470	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_22490	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
At12D1_22500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_22510	COG1940	carbohydrate kinase activity
At12D1_22520	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_22530	COG1129	ABC transporter
At12D1_22540	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_22550	COG1879	ABC-type sugar transport system periplasmic component
At12D1_22560	COG2972	Histidine kinase
At12D1_22560	COG0840	transmembrane signaling receptor activity
At12D1_22570	COG1126	abc transporter atp-binding protein
At12D1_22580	COG0765	amino acid transport
At12D1_22590	COG2963	transposase activity
At12D1_22600	COG3436	PFAM IS66 Orf2 family protein
At12D1_22610	COG2433	Pfam Transposase IS66
At12D1_22630	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
At12D1_22640	COG2301	Belongs to the HpcH HpaI aldolase family
At12D1_22670	COG0745	RESPONSE REGULATOR receiver
At12D1_22680	COG2205	protein histidine kinase activity
At12D1_22750	COG2948	multi-organism process
At12D1_22810	COG3451	type IV secretory pathway VirB4
At12D1_22830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
At12D1_22870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
At12D1_22890	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
At12D1_22920	COG5489	Protein of unknown function (DUF736)
At12D1_23020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
At12D1_23030	COG1309	transcriptional regulator
At12D1_23040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_23050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At12D1_23070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
At12D1_23080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
At12D1_23120	COG0583	DNA-binding transcription factor activity
At12D1_23130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_23140	COG0725	ABC transporter, periplasmic molybdate-binding protein
At12D1_23150	COG4149	molybdate abc transporter
At12D1_23160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
At12D1_23190	COG2022	thiamine diphosphate biosynthetic process
At12D1_23220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
At12D1_23240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At12D1_23260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
At12D1_23300	COG1132	(ABC) transporter
At12D1_23310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
At12D1_23400	COG4166	transmembrane transport
At12D1_23410	COG0601	transmembrane transport
At12D1_23420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_23450	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
At12D1_23460	COG3142	Participates in the control of copper homeostasis
At12D1_23470	COG2814	Major facilitator Superfamily
At12D1_23500	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_23510	COG1737	Transcriptional regulator
At12D1_23530	COG3842	ATPase activity
At12D1_23550	COG0395	ABC-type sugar transport system, permease component
At12D1_23600	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
At12D1_23610	COG1940	carbohydrate kinase activity
At12D1_23630	COG0671	phosphoesterase, PA-phosphatase related
At12D1_23640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
At12D1_23650	COG0156	8-amino-7-oxononanoate synthase activity
At12D1_23670	COG0729	surface antigen
At12D1_23690	COG0835	chemotaxis
At12D1_23710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
At12D1_23720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
At12D1_23730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
At12D1_23740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
At12D1_23750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
At12D1_23760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
At12D1_23790	COG4974	Belongs to the 'phage' integrase family
At12D1_23840	COG1280	lysine exporter protein (LysE YggA)
At12D1_23860	COG0508	dehydrogenase complex catalyzes the overall conversion of
At12D1_23880	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
At12D1_23890	COG0045	succinate-CoA ligase (ADP-forming) activity
At12D1_23900	COG0039	L-malate dehydrogenase activity
At12D1_23910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
At12D1_23980	COG2264	protein methyltransferase activity
At12D1_24010	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
At12D1_24020	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
At12D1_24030	COG0181	hydroxymethylbilane synthase activity
At12D1_24110	COG1872	DUF167
At12D1_24120	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
At12D1_24150	COG0339	signal peptide processing
At12D1_24160	COG1846	Transcriptional regulator
At12D1_24180	COG0137	argininosuccinate synthase activity
At12D1_24200	COG1280	lysine exporter protein (LysE YggA)
At12D1_24220	COG4120	Belongs to the binding-protein-dependent transport system permease family
At12D1_24240	COG0820	rRNA (adenine-C2-)-methyltransferase activity
At12D1_24270	COG2154	pterin-4-alpha-carbinolamine dehydratase
At12D1_24280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
At12D1_24290	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
At12D1_24310	COG4181	ATPase activity
At12D1_24330	COG0670	Belongs to the BI1 family
At12D1_24360	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
At12D1_24370	COG4133	protoheme IX ABC transporter activity
At12D1_24380	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
At12D1_24390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
At12D1_24420	COG3706	GGDEF domain
At12D1_24440	COG2917	probably involved in intracellular septation
At12D1_24450	COG0552	protein localization to endoplasmic reticulum
At12D1_24460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
At12D1_24470	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
At12D1_24490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
At12D1_24500	COG0287	Prephenate dehydrogenase
At12D1_24500	COG1605	Chorismate mutase
At12D1_24510	COG0228	four-way junction DNA binding
At12D1_24520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
At12D1_24530	COG0336	Belongs to the RNA methyltransferase TrmD family
At12D1_24550	COG0335	large ribosomal subunit rRNA binding
At12D1_24560	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
At12D1_24570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_24600	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
At12D1_24630	COG4783	chaperone-mediated protein folding
At12D1_24640	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
At12D1_24700	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
At12D1_24720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
At12D1_24730	COG0142	geranyltranstransferase activity
At12D1_24740	COG2885	chlorophyll binding
At12D1_24750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
At12D1_24760	COG2223	nitrite transmembrane transporter activity
At12D1_24770	COG1349	DNA-binding transcription factor activity
At12D1_24780	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
At12D1_24790	COG2197	response regulator
At12D1_24800	COG1132	(ABC) transporter
At12D1_24820	COG3459	Glycosyltransferase 36 associated
At12D1_24830	COG1473	amidohydrolase
At12D1_24850	COG0579	oxidoreductase
At12D1_24870	COG0129	dihydroxy-acid dehydratase activity
At12D1_24880	COG2084	Dehydrogenase
At12D1_24890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At12D1_24900	COG0277	FAD linked oxidase domain protein
At12D1_24910	COG1609	Transcriptional regulator
At12D1_24930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
At12D1_24940	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At12D1_24950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At12D1_24960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
At12D1_24980	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
At12D1_24990	COG0495	leucyl-tRNA aminoacylation
At12D1_25030	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
At12D1_25050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
At12D1_25060	COG1946	Acyl-CoA thioesterase
At12D1_25070	COG0347	Belongs to the P(II) protein family
At12D1_25080	COG0004	ammonium transporteR
At12D1_25090	COG1674	ftsk spoiiie
At12D1_25100	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
At12D1_25130	COG0745	RESPONSE REGULATOR receiver
At12D1_25150	COG1329	Transcriptional regulator
At12D1_25170	COG2270	Major facilitator Superfamily
At12D1_25200	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_25230	COG0494	nUDIX hydrolase
At12D1_25240	COG2861	carbohydrate metabolic process
At12D1_25250	COG0793	Belongs to the peptidase S41A family
At12D1_25270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
At12D1_25280	COG0799	negative regulation of ribosome biogenesis
At12D1_25290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
At12D1_25300	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
At12D1_25310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
At12D1_25320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
At12D1_25350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
At12D1_25360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
At12D1_25420	COG0066	3-isopropylmalate dehydratase activity
At12D1_25430	COG0473	3-isopropylmalate dehydrogenase activity
At12D1_25440	COG1858	cytochrome C peroxidase
At12D1_25450	COG1797	cobyrinic acid a,c-diamide synthase activity
At12D1_25470	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
At12D1_25600	COG1492	cobalamin metabolic process
At12D1_25630	COG4948	Mandelate Racemase Muconate Lactonizing
At12D1_25640	COG3254	rhamnose metabolic process
At12D1_25660	COG1063	alcohol dehydrogenase
At12D1_25710	COG1129	ABC transporter
At12D1_25720	COG2186	Transcriptional regulator
At12D1_25730	COG2721	sulfolactate sulfo-lyase activity
At12D1_25740	COG0138	bifunctional purine biosynthesis protein purh
At12D1_25760	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
At12D1_25760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
At12D1_25770	COG0501	Belongs to the peptidase M48B family
At12D1_25790	COG1475	DNA binding
At12D1_25800	COG1192	Involved in chromosome partitioning
At12D1_25810	COG0357	Ribosomal RNA small subunit methyltransferase G
At12D1_25820	COG0445	tRNA wobble uridine modification
At12D1_25830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
At12D1_25840	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
At12D1_25860	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
At12D1_25870	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
At12D1_25880	COG0424	maF-like protein
At12D1_25890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
At12D1_25900	COG0237	dephospho-CoA kinase activity
At12D1_25910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
At12D1_25920	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
At12D1_25930	COG3030	protein affecting phage T7 exclusion by the F plasmid
At12D1_25950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
At12D1_25980	COG0187	DNA topoisomerase II activity
At12D1_26000	COG0179	Fumarylacetoacetate (FAA) hydrolase
At12D1_26030	COG0135	phosphoribosylanthranilate isomerase activity
At12D1_26040	COG0133	tryptophan synthase activity
At12D1_26050	COG0159	tryptophan synthase activity
At12D1_26060	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
At12D1_26090	COG1074	ATP-dependent DNA helicase activity
At12D1_26110	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
At12D1_26120	COG0802	atpase or kinase
At12D1_26130	COG2205	protein histidine kinase activity
At12D1_26140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
At12D1_26150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
At12D1_26160	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
At12D1_26160	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
At12D1_26170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
At12D1_26180	COG0642	Histidine kinase
At12D1_26190	COG0745	RESPONSE REGULATOR receiver
At12D1_26200	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
At12D1_26220	COG1652	LysM domain
At12D1_26230	COG1072	(Pantothenic acid kinase))
At12D1_26240	COG0140	phosphoribosyl-ATP diphosphatase activity
At12D1_26250	COG0107	imidazoleglycerol-phosphate synthase activity
At12D1_26260	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
At12D1_26270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
At12D1_26290	COG0131	Imidazoleglycerol-phosphate dehydratase
At12D1_26300	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
At12D1_26310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
At12D1_26330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
At12D1_26360	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
At12D1_26380	COG1643	Atp-dependent helicase
At12D1_26400	COG2801	Transposase and inactivated derivatives
At12D1_26470	COG1072	(Pantothenic acid kinase))
At12D1_26490	COG1780	Probably involved in ribonucleotide reductase function
At12D1_26530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
At12D1_26590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_26610	COG2813	Specifically methylates the guanine in position
At12D1_26620	COG1185	polyribonucleotide nucleotidyltransferase activity
At12D1_26630	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
At12D1_26640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
At12D1_26650	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
At12D1_26660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
At12D1_26660	COG3064	Membrane
At12D1_26690	COG0779	Required for maturation of 30S ribosomal subunits
At12D1_26700	COG2814	Major facilitator Superfamily
At12D1_26710	COG2951	lytic endotransglycosylase activity
At12D1_26720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
At12D1_26740	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
At12D1_26750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
At12D1_26770	COG2816	NAD+ diphosphatase activity
At12D1_26780	COG0077	Prephenate dehydratase
At12D1_26780	COG1605	Chorismate mutase
At12D1_26790	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
At12D1_26800	COG3474	cytochrome
At12D1_26820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
At12D1_26830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
At12D1_26840	COG1278	Cold shock
At12D1_26850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
At12D1_26870	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
At12D1_26870	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
At12D1_26880	COG0333	Belongs to the bacterial ribosomal protein bL32 family
At12D1_26940	COG2900	Belongs to the SlyX family
At12D1_26960	COG0484	heat shock protein binding
At12D1_26970	COG0443	Heat shock 70 kDa protein
At12D1_26990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
At12D1_27040	COG0295	cytidine deaminase activity
At12D1_27050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
At12D1_27060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
At12D1_27070	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
At12D1_27090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
At12D1_27100	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
At12D1_27110	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
At12D1_27130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
At12D1_27140	COG1845	cytochrome c oxidase, subunit III
At12D1_27150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
At12D1_27160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
At12D1_27170	COG0477	Major facilitator Superfamily
At12D1_27180	COG0070	glutamate synthase
At12D1_27180	COG0069	glutamate synthase activity
At12D1_27180	COG0067	glutamate synthase
At12D1_27190	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
At12D1_27220	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
At12D1_27240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
At12D1_27300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_27340	COG0848	biopolymer transport protein
At12D1_27360	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
At12D1_27390	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
At12D1_27400	COG3454	Phosphonate metabolism
At12D1_27410	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
At12D1_27420	COG3639	organic phosphonate transmembrane transporter activity
At12D1_27430	COG3639	organic phosphonate transmembrane transporter activity
At12D1_27450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
At12D1_27470	COG4778	phosphonate C-P lyase system protein PhnL
At12D1_27480	COG4107	phosphonate C-P lyase system protein PhnK
At12D1_27490	COG3627	carbon phosphorus lyase activity
At12D1_27510	COG3626	phosphonate metabolism
At12D1_27520	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
At12D1_27530	COG3624	Phosphonate C-P lyase system protein PhnG
At12D1_27540	COG2188	Transcriptional regulator
At12D1_27550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
At12D1_27560	COG0837	glucose binding
At12D1_27570	COG1803	Methylglyoxal synthase
At12D1_27580	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
At12D1_27590	COG4166	transmembrane transport
At12D1_27600	COG4174	ABC transporter (Permease)
At12D1_27610	COG4239	(ABC) transporter, permease
At12D1_27620	COG4172	Belongs to the ABC transporter superfamily
At12D1_27630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_27640	COG0174	glutamine synthetase
At12D1_27650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_27660	COG3265	gluconokinase activity
At12D1_27670	COG1174	glycine betaine transport
At12D1_27680	COG1125	glycine betaine transport
At12D1_27690	COG1174	glycine betaine transport
At12D1_27700	COG1732	Glycine betaine
At12D1_27720	COG1959	2 iron, 2 sulfur cluster binding
At12D1_27730	COG1840	ABC-type Fe3 transport system, periplasmic component
At12D1_27740	COG0501	Belongs to the peptidase M48B family
At12D1_27750	COG4269	membrane
At12D1_27780	COG0697	spore germination
At12D1_27810	COG0791	NLP P60 protein
At12D1_27830	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
At12D1_27840	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
At12D1_27910	COG4964	Belongs to the GSP D family
At12D1_27990	COG3422	double-strand break repair
At12D1_28000	COG3757	hydrolase, family 25
At12D1_28010	COG0697	spore germination
At12D1_28020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At12D1_28050	COG0492	ferredoxin-NADP+ reductase activity
At12D1_28080	COG0481	GTPase activity
At12D1_28090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_28120	COG1396	sequence-specific DNA binding
At12D1_28150	COG1917	Cupin 2, conserved barrel domain protein
At12D1_28150	COG2169	Transcriptional regulator
At12D1_28160	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
At12D1_28210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
At12D1_28220	COG0291	Belongs to the bacterial ribosomal protein bL35 family
At12D1_28230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
At12D1_28250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
At12D1_28260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
At12D1_28260	COG0072	phenylalanine-tRNA ligase activity
At12D1_28270	COG0667	Aldo Keto reductase
At12D1_28310	COG4977	sequence-specific DNA binding
At12D1_28360	COG1570	exodeoxyribonuclease VII activity
At12D1_28370	COG4948	Mandelate Racemase Muconate Lactonizing
At12D1_28390	COG1846	Transcriptional regulator
At12D1_28400	COG0697	spore germination
At12D1_28410	COG2309	aminopeptidase activity
At12D1_28430	COG1393	Belongs to the ArsC family
At12D1_28470	COG1309	transcriptional regulator
At12D1_28490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
At12D1_28490	COG0519	Catalyzes the synthesis of GMP from XMP
At12D1_28520	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
At12D1_28580	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
At12D1_28600	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
At12D1_28620	COG1968	undecaprenyl-diphosphatase activity
At12D1_28650	COG0284	orotidine-5'-phosphate decarboxylase activity
At12D1_28670	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
At12D1_28680	COG0592	DNA-directed DNA polymerase activity
At12D1_28690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
At12D1_28700	COG0792	nuclease activity
At12D1_28730	COG1175	transmembrane transport
At12D1_28740	COG0395	ABC-type sugar transport system, permease component
At12D1_28750	COG3842	ATPase activity
At12D1_28770	COG0189	ligase activity
At12D1_28790	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
At12D1_28800	COG1280	lysine exporter protein (LysE YggA)
At12D1_28810	COG0756	dUTP diphosphatase activity
At12D1_28820	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
At12D1_28830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
At12D1_28860	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
At12D1_28870	COG2226	methyltransferase
At12D1_28880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
At12D1_28890	COG1024	Enoyl-CoA hydratase
At12D1_28900	COG0268	Binds directly to 16S ribosomal RNA
At12D1_28960	COG4106	trans-aconitate 2-methyltransferase activity
At12D1_29000	COG1278	Cold shock
At12D1_29070	COG0411	ABC transporter
At12D1_29080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
At12D1_29090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_29100	COG1454	alcohol dehydrogenase
At12D1_29110	COG0747	negative chemotaxis
At12D1_29120	COG0601	transmembrane transport
At12D1_29140	COG4608	Belongs to the ABC transporter superfamily
At12D1_29150	COG1349	DNA-binding transcription factor activity
At12D1_29160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
At12D1_29210	COG4302	ethanolamine ammonia-lyase activity
At12D1_29220	COG0025	NhaP-type Na H and K H
At12D1_29230	COG4106	trans-aconitate 2-methyltransferase activity
At12D1_29250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_29260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_29270	COG0601	transmembrane transport
At12D1_29320	COG4172	Belongs to the ABC transporter superfamily
At12D1_29330	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
At12D1_29340	COG3706	GGDEF domain
At12D1_29350	COG2814	Major facilitator Superfamily
At12D1_29400	COG0745	RESPONSE REGULATOR receiver
At12D1_29410	COG2205	protein histidine kinase activity
At12D1_29420	COG1764	response to oxidative stress
At12D1_29440	COG0596	Alpha beta hydrolase
At12D1_29480	COG0783	Belongs to the Dps family
At12D1_29490	COG0243	molybdopterin cofactor binding
At12D1_29510	COG4566	intracellular signal transduction
At12D1_29520	COG4566	intracellular signal transduction
At12D1_29540	COG2140	Oxalate decarboxylase
At12D1_29580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At12D1_29600	COG1414	Transcriptional regulator
At12D1_29620	COG0318	PFAM AMP-dependent synthetase and ligase
At12D1_29630	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_29670	COG1522	sequence-specific DNA binding
At12D1_29700	COG0628	permease
At12D1_29720	COG2235	arginine
At12D1_29790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
At12D1_29810	COG0702	epimerase
At12D1_29820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At12D1_29830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_29840	COG0745	RESPONSE REGULATOR receiver
At12D1_29850	COG5002	protein histidine kinase activity
At12D1_29880	COG2233	PERMEase
At12D1_30000	COG0395	ABC-type sugar transport system, permease component
At12D1_30010	COG1176	ABC-type spermidine putrescine transport system, permease component I
At12D1_30030	COG3842	ATPase activity
At12D1_30110	COG1653	transport
At12D1_30120	COG1175	transmembrane transport
At12D1_30130	COG0395	ABC-type sugar transport system, permease component
At12D1_30140	COG3842	ATPase activity
At12D1_30160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_30170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_30180	COG1116	anion transmembrane transporter activity
At12D1_30190	COG0395	ABC-type sugar transport system, permease component
At12D1_30200	COG1175	transmembrane transport
At12D1_30260	COG1609	Transcriptional regulator
At12D1_30290	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_30300	COG3842	ATPase activity
At12D1_30310	COG0395	ABC-type sugar transport system, permease component
At12D1_30320	COG1175	transmembrane transport
At12D1_30330	COG1653	transport
At12D1_30340	COG1309	transcriptional regulator
At12D1_30350	COG0673	inositol 2-dehydrogenase activity
At12D1_30380	COG0673	inositol 2-dehydrogenase activity
At12D1_30410	COG1278	Cold shock
At12D1_30430	COG0828	Belongs to the bacterial ribosomal protein bS21 family
At12D1_30490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
At12D1_30500	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
At12D1_30540	COG0395	ABC-type sugar transport system, permease component
At12D1_30550	COG1175	transmembrane transport
At12D1_30570	COG3618	amidohydrolase
At12D1_30580	COG4948	Mandelate Racemase Muconate Lactonizing
At12D1_30590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_30600	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_30610	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
At12D1_30620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At12D1_30630	COG2186	Transcriptional regulator
At12D1_30660	COG0667	Aldo Keto reductase
At12D1_30720	COG4977	sequence-specific DNA binding
At12D1_30730	COG2223	nitrite transmembrane transporter activity
At12D1_30740	COG1609	Transcriptional regulator
At12D1_30750	COG1063	alcohol dehydrogenase
At12D1_30760	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_30780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_30790	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
At12D1_30800	COG1175	transmembrane transport
At12D1_30810	COG0395	ABC-type sugar transport system, permease component
At12D1_30840	COG0395	ABC-type sugar transport system, permease component
At12D1_30870	COG0626	cystathionine gamma-synthase activity
At12D1_30900	COG0454	-acetyltransferase
At12D1_30910	COG0803	Belongs to the bacterial solute-binding protein 9 family
At12D1_30930	COG1121	(ABC) transporter
At12D1_30940	COG0523	cobalamin synthesis protein
At12D1_30970	COG0523	cobalamin synthesis protein
At12D1_30980	COG1653	transport
At12D1_30990	COG1175	transmembrane transport
At12D1_31000	COG0395	ABC-type sugar transport system, permease component
At12D1_31010	COG3842	ATPase activity
At12D1_31030	COG3047	cAMP biosynthetic process
At12D1_31080	COG0583	DNA-binding transcription factor activity
At12D1_31090	COG1879	ABC-type sugar transport system periplasmic component
At12D1_31100	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_31110	COG1129	ABC transporter
At12D1_31130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
At12D1_31140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_31160	COG3257	ureidoglycine aminohydrolase activity
At12D1_31180	COG5001	Diguanylate cyclase
At12D1_31190	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
At12D1_31210	COG0747	negative chemotaxis
At12D1_31220	COG0601	transmembrane transport
At12D1_31230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_31250	COG4608	Belongs to the ABC transporter superfamily
At12D1_31260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
At12D1_31290	COG0346	lactoylglutathione lyase activity
At12D1_31300	COG0129	dihydroxy-acid dehydratase activity
At12D1_31310	COG1879	ABC-type sugar transport system periplasmic component
At12D1_31320	COG1129	ABC transporter
At12D1_31330	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_31340	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_31350	COG2186	Transcriptional regulator
At12D1_31380	COG2226	methyltransferase
At12D1_31390	COG0587	DNA-directed DNA polymerase activity
At12D1_31400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
At12D1_31450	COG0673	inositol 2-dehydrogenase activity
At12D1_31470	COG3842	ATPase activity
At12D1_31480	COG0395	ABC-type sugar transport system, permease component
At12D1_31490	COG1175	transmembrane transport
At12D1_31500	COG1653	transport
At12D1_31520	COG0673	inositol 2-dehydrogenase activity
At12D1_31550	COG5001	Diguanylate cyclase
At12D1_31580	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
At12D1_31590	COG2894	cell division
At12D1_31600	COG0850	regulation of cytokinetic process
At12D1_31610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
At12D1_31620	COG2186	Transcriptional regulator
At12D1_31630	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At12D1_31650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At12D1_31660	COG1063	alcohol dehydrogenase
At12D1_31670	COG1312	Catalyzes the dehydration of D-mannonate
At12D1_31710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
At12D1_31720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
At12D1_31730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_31750	COG0640	Transcriptional regulator
At12D1_31760	COG0625	glutathione transferase activity
At12D1_31770	COG4172	Belongs to the ABC transporter superfamily
At12D1_31780	COG1921	L-seryl-tRNASec selenium transferase activity
At12D1_31810	COG3964	amidohydrolase
At12D1_31830	COG0601	transmembrane transport
At12D1_31840	COG0747	negative chemotaxis
At12D1_31850	COG0438	transferase activity, transferring glycosyl groups
At12D1_31920	COG4989	oxidoreductase activity
At12D1_31950	COG3842	ATPase activity
At12D1_31960	COG1653	transport
At12D1_31970	COG1175	transmembrane transport
At12D1_31980	COG0395	ABC-type sugar transport system, permease component
At12D1_31990	COG1501	Belongs to the glycosyl hydrolase 31 family
At12D1_32010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_32020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_32030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
At12D1_32040	COG0352	thiamine-phosphate diphosphorylase activity
At12D1_32050	COG0351	phosphomethylpyrimidine kinase
At12D1_32060	COG1522	sequence-specific DNA binding
At12D1_32070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
At12D1_32080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_32110	COG2204	response regulator
At12D1_32120	COG4191	Histidine kinase
At12D1_32130	COG1301	dicarboxylic acid transport
At12D1_32140	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
At12D1_32150	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_32210	COG1215	transferase activity, transferring glycosyl groups
At12D1_32230	COG2942	2-epimerase
At12D1_32280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At12D1_32300	COG2197	response regulator
At12D1_32360	COG3307	-O-antigen
At12D1_32370	COG1596	polysaccharide export
At12D1_32380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
At12D1_32410	COG0840	transmembrane signaling receptor activity
At12D1_32410	COG2972	Histidine kinase
At12D1_32420	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_32440	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_32460	COG2094	Belongs to the DNA glycosylase MPG family
At12D1_32490	COG1609	Transcriptional regulator
At12D1_32500	COG1653	transport
At12D1_32530	COG3842	ATPase activity
At12D1_32550	COG0673	inositol 2-dehydrogenase activity
At12D1_32560	COG0602	queuosine metabolic process
At12D1_32570	COG0720	synthase
At12D1_32580	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
At12D1_32610	COG0673	inositol 2-dehydrogenase activity
At12D1_32640	COG0395	ABC-type sugar transport system, permease component
At12D1_32710	COG0583	DNA-binding transcription factor activity
At12D1_32720	COG0281	malic enzyme
At12D1_32720	COG0280	phosphate acetyltransferase
At12D1_32750	COG0765	amino acid transport
At12D1_32760	COG1126	abc transporter atp-binding protein
At12D1_32770	COG2079	MmgE PrpD family protein
At12D1_32800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_32830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
At12D1_32850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
At12D1_32860	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
At12D1_32870	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_32880	COG1129	ABC transporter
At12D1_32900	COG1473	amidohydrolase
At12D1_32910	COG0747	negative chemotaxis
At12D1_32950	COG0601	transmembrane transport
At12D1_32960	COG0583	DNA-binding transcription factor activity
At12D1_32970	COG1446	asparaginase
At12D1_33000	COG0747	negative chemotaxis
At12D1_33050	COG0601	transmembrane transport
At12D1_33060	COG2197	response regulator
At12D1_33070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
At12D1_33080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At12D1_33110	COG0395	ABC-type sugar transport system, permease component
At12D1_33120	COG1175	transmembrane transport
At12D1_33140	COG0673	inositol 2-dehydrogenase activity
At12D1_33150	COG0673	inositol 2-dehydrogenase activity
At12D1_33190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_33200	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
At12D1_33240	COG1595	DNA-templated transcription, initiation
At12D1_33250	COG1120	ATPase activity
At12D1_33260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_33290	COG2226	methyltransferase
At12D1_33310	COG1120	ATPase activity
At12D1_33320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_33360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
At12D1_33410	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_33420	COG0473	3-isopropylmalate dehydrogenase activity
At12D1_33430	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_33440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_33520	COG4172	Belongs to the ABC transporter superfamily
At12D1_33530	COG1522	sequence-specific DNA binding
At12D1_33550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_33580	COG0583	DNA-binding transcription factor activity
At12D1_33610	COG1126	abc transporter atp-binding protein
At12D1_33630	COG1473	amidohydrolase
At12D1_33640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_33650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_33660	COG1959	2 iron, 2 sulfur cluster binding
At12D1_33680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At12D1_33690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_33750	COG1960	acyl-CoA dehydrogenase activity
At12D1_33770	COG0747	negative chemotaxis
At12D1_33800	COG0444	Belongs to the ABC transporter superfamily
At12D1_33820	COG0667	Aldo Keto reductase
At12D1_33840	COG0583	DNA-binding transcription factor activity
At12D1_33860	COG4166	transmembrane transport
At12D1_33880	COG0747	negative chemotaxis
At12D1_33890	COG1473	amidohydrolase
At12D1_33900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_33940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_33980	COG4608	Belongs to the ABC transporter superfamily
At12D1_33990	COG0444	Belongs to the ABC transporter superfamily
At12D1_34010	COG0601	transmembrane transport
At12D1_34030	COG2186	Transcriptional regulator
At12D1_34060	COG0300	oxidoreductase activity
At12D1_34080	COG3453	Protein conserved in bacteria
At12D1_34080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
At12D1_34090	COG0640	Transcriptional regulator
At12D1_34110	COG2391	methyltransferase activity
At12D1_34120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
At12D1_34140	COG0022	dehydrogenase e1 component
At12D1_34160	COG1960	acyl-CoA dehydrogenase activity
At12D1_34170	COG0183	Belongs to the thiolase family
At12D1_34190	COG1960	acyl-CoA dehydrogenase activity
At12D1_34200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
At12D1_34240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
At12D1_34250	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
At12D1_34260	COG4952	isomerase
At12D1_34270	COG3347	Dehydrogenase
At12D1_34270	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_34280	COG1349	DNA-binding transcription factor activity
At12D1_34300	COG1129	ABC transporter
At12D1_34310	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_34320	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_34330	COG3254	rhamnose metabolic process
At12D1_34360	COG2264	protein methyltransferase activity
At12D1_34370	COG5001	Diguanylate cyclase
At12D1_34400	COG4335	DNA alkylation repair
At12D1_34410	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
At12D1_34420	COG4208	sulfate ABC transporter
At12D1_34440	COG4150	thiosulfate binding
At12D1_34460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
At12D1_34490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
At12D1_34510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_34530	COG1040	competence protein
At12D1_34540	COG2226	methyltransferase
At12D1_34570	COG0494	nUDIX hydrolase
At12D1_34590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
At12D1_34600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
At12D1_34610	COG0653	protein targeting
At12D1_34620	COG0697	spore germination
At12D1_34740	COG2244	polysaccharide biosynthetic process
At12D1_34780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
At12D1_34800	COG0489	protein tyrosine kinase activity
At12D1_34800	COG3206	protein involved in exopolysaccharide biosynthesis
At12D1_34840	COG0438	transferase activity, transferring glycosyl groups
At12D1_34850	COG0438	transferase activity, transferring glycosyl groups
At12D1_34880	COG2963	transposase activity
At12D1_34890	COG3436	PFAM IS66 Orf2 family protein
At12D1_34900	COG2433	Pfam Transposase IS66
At12D1_34930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
At12D1_34940	COG2273	Hydrolase Family 16
At12D1_34940	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
At12D1_34970	COG3842	ATPase activity
At12D1_34980	COG3833	ABC-type maltose transport systems, permease component
At12D1_35090	COG1396	sequence-specific DNA binding
At12D1_35120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
At12D1_35130	COG1129	ABC transporter
At12D1_35140	COG4214	carbohydrate transport
At12D1_35150	COG4213	ABC transporter substrate-binding protein
At12D1_35230	COG0625	glutathione transferase activity
At12D1_35240	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
At12D1_35250	COG1396	sequence-specific DNA binding
At12D1_35250	COG3800	Transcriptional regulator
At12D1_35270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
At12D1_35290	COG0300	oxidoreductase activity
At12D1_35310	COG2096	Adenosyltransferase
At12D1_35330	COG2086	electron transfer activity
At12D1_35350	COG1250	3-hydroxyacyl-CoA dehydrogenase
At12D1_35370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
At12D1_35380	COG0165	Argininosuccinate lyase
At12D1_35450	COG2884	Cell division ATP-binding protein ftsE
At12D1_35490	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
At12D1_35510	COG0287	Prephenate dehydrogenase
At12D1_35520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
At12D1_35530	COG2226	methyltransferase
At12D1_35540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
At12D1_35570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
At12D1_35580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
At12D1_35660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
At12D1_35670	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
At12D1_35690	COG4974	Belongs to the 'phage' integrase family
At12D1_35700	COG0825	malonyl-CoA metabolic process
At12D1_35710	COG3034	peptidoglycan biosynthetic process
At12D1_35720	COG0425	Belongs to the sulfur carrier protein TusA family
At12D1_35720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
At12D1_35730	COG0523	cobalamin synthesis protein
At12D1_35740	COG1686	Belongs to the peptidase S11 family
At12D1_35750	COG1473	amidohydrolase
At12D1_35770	COG4953	penicillin-binding protein 1C
At12D1_35780	COG2373	Large extracellular alpha-helical protein
At12D1_35790	COG2835	tetraacyldisaccharide 4'-kinase activity
At12D1_35840	COG0482	sulfurtransferase activity
At12D1_35870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
At12D1_35900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
At12D1_35910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
At12D1_35920	COG0037	tRNA processing
At12D1_35940	COG2885	chlorophyll binding
At12D1_35950	COG0823	Involved in the tonB-independent uptake of proteins
At12D1_35990	COG0824	Thioesterase
At12D1_36010	COG0494	nUDIX hydrolase
At12D1_36040	COG2255	four-way junction helicase activity
At12D1_36050	COG0632	four-way junction helicase activity
At12D1_36060	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
At12D1_36070	COG0840	transmembrane signaling receptor activity
At12D1_36080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_36090	COG0217	transcriptional regulatory protein
At12D1_36120	COG1692	metallophosphoesterase
At12D1_36140	COG1253	flavin adenine dinucleotide binding
At12D1_36210	COG0126	phosphoglycerate kinase activity
At12D1_36220	COG3588	fructose-bisphosphate aldolase
At12D1_36270	COG0254	rRNA binding
At12D1_36280	COG1132	(ABC) transporter
At12D1_36330	COG0483	inositol monophosphate 1-phosphatase activity
At12D1_36390	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
At12D1_36400	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
At12D1_36410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
At12D1_36420	COG0457	Tetratricopeptide repeat
At12D1_36430	COG3750	Belongs to the UPF0335 family
At12D1_36470	COG0469	pyruvate kinase activity
At12D1_36480	COG3108	Peptidase M15
At12D1_36490	COG2204	response regulator
At12D1_36500	COG1164	Oligoendopeptidase f
At12D1_36510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
At12D1_36520	COG0745	RESPONSE REGULATOR receiver
At12D1_36520	COG3706	GGDEF domain
At12D1_36530	COG5310	Homospermidine synthase
At12D1_36550	COG0737	Belongs to the 5'-nucleotidase family
At12D1_36560	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
At12D1_36570	COG0330	HflC and HflK could
At12D1_36620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
At12D1_36630	COG2951	lytic endotransglycosylase activity
At12D1_36660	COG2205	protein histidine kinase activity
At12D1_36680	COG0069	glutamate synthase activity
At12D1_36680	COG0067	glutamate synthase
At12D1_36680	COG0070	glutamate synthase
At12D1_36710	COG2205	protein histidine kinase activity
At12D1_36720	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
At12D1_36730	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
At12D1_36750	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
At12D1_36770	COG0252	asparaginase activity
At12D1_36790	COG1027	Aspartate ammonia-lyase
At12D1_36800	COG2186	Transcriptional regulator
At12D1_36840	COG1309	transcriptional regulator
At12D1_36880	COG4176	ABC-type proline glycine betaine transport system permease component
At12D1_36890	COG4175	Glycine betaine
At12D1_36890	COG0517	IMP dehydrogenase activity
At12D1_36900	COG2986	histidine ammonia-lyase
At12D1_36910	COG1609	Transcriptional regulator
At12D1_36950	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_36960	COG0673	inositol 2-dehydrogenase activity
At12D1_36970	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_36990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_37000	COG4172	Belongs to the ABC transporter superfamily
At12D1_37020	COG0601	transmembrane transport
At12D1_37030	COG0747	negative chemotaxis
At12D1_37050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
At12D1_37060	COG1454	alcohol dehydrogenase
At12D1_37070	COG2186	Transcriptional regulator
At12D1_37100	COG1607	acyl-coa hydrolase
At12D1_37140	COG2307	Protein conserved in bacteria
At12D1_37140	COG2308	Evidence 4 Homologs of previously reported genes of
At12D1_37170	COG0488	(ABC) transporter
At12D1_37180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At12D1_37190	COG2186	Transcriptional regulator
At12D1_37220	COG1175	transmembrane transport
At12D1_37230	COG0395	ABC-type sugar transport system, permease component
At12D1_37250	COG3842	ATPase activity
At12D1_37290	COG2171	N-acyltransferase activity
At12D1_37300	COG1304	FMN binding
At12D1_37330	COG1063	alcohol dehydrogenase
At12D1_37340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
At12D1_37350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_37370	COG0765	amino acid transport
At12D1_37380	COG0765	amino acid transport
At12D1_37390	COG4221	oxidoreductase activity
At12D1_37400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At12D1_37410	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_37420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At12D1_37450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
At12D1_37480	COG0697	spore germination
At12D1_37490	COG0697	spore germination
At12D1_37500	COG0511	ligase activity, forming carbon-carbon bonds
At12D1_37510	COG0439	Biotin carboxylase
At12D1_37530	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
At12D1_37540	COG1984	allophanate hydrolase subunit 2
At12D1_37550	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
At12D1_37560	COG3842	ATPase activity
At12D1_37580	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
At12D1_37590	COG1176	ABC-type spermidine putrescine transport system, permease component I
At12D1_37630	COG2972	Histidine kinase
At12D1_37630	COG0840	transmembrane signaling receptor activity
At12D1_37640	COG1070	Carbohydrate kinase
At12D1_37650	COG1830	Aldolase
At12D1_37660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
At12D1_37670	COG0667	Aldo Keto reductase
At12D1_37690	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_37700	COG1129	ABC transporter
At12D1_37760	COG0071	Belongs to the small heat shock protein (HSP20) family
At12D1_37790	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
At12D1_37820	COG0395	ABC-type sugar transport system, permease component
At12D1_37850	COG3842	ATPase activity
At12D1_37880	COG1648	precorrin-2 dehydrogenase activity
At12D1_37880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
At12D1_37890	COG0243	molybdopterin cofactor binding
At12D1_37920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
At12D1_37930	COG1116	anion transmembrane transporter activity
At12D1_37940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_37950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_37970	COG3707	response regulator
At12D1_37980	COG1802	Transcriptional regulator
At12D1_37990	COG1914	H( )-stimulated, divalent metal cation uptake system
At12D1_38000	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
At12D1_38010	COG4336	lyase activity
At12D1_38020	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
At12D1_38030	COG4770	biotin carboxylase activity
At12D1_38040	COG0366	Alpha amylase catalytic
At12D1_38060	COG4771	TonB-dependent receptor
At12D1_38070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
At12D1_38110	COG1414	Transcriptional regulator
At12D1_38120	COG1475	DNA binding
At12D1_38130	COG1192	Involved in chromosome partitioning
At12D1_38200	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
At12D1_38220	COG2986	histidine ammonia-lyase
At12D1_38230	COG1228	amidohydrolase
At12D1_38240	COG0402	S-adenosylhomocysteine deaminase activity
At12D1_38280	COG2801	Transposase and inactivated derivatives
At12D1_38290	COG4172	Belongs to the ABC transporter superfamily
At12D1_38300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_38310	COG0601	transmembrane transport
At12D1_38320	COG4166	transmembrane transport
At12D1_38330	COG0395	ABC-type sugar transport system, permease component
At12D1_38360	COG1566	PFAM secretion protein HlyD family protein
At12D1_38400	COG2207	Transcriptional regulator
At12D1_38410	COG1309	transcriptional regulator
At12D1_38420	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_38470	COG1846	Transcriptional regulator
At12D1_38480	COG0583	DNA-binding transcription factor activity
At12D1_38490	COG2828	Protein conserved in bacteria
At12D1_38520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_38550	COG0840	transmembrane signaling receptor activity
At12D1_38590	COG1215	transferase activity, transferring glycosyl groups
At12D1_38650	COG0583	DNA-binding transcription factor activity
At12D1_38660	COG0346	lactoylglutathione lyase activity
At12D1_38690	COG1574	metal-dependent hydrolase with the TIM-barrel fold
At12D1_38730	COG0583	DNA-binding transcription factor activity
At12D1_38740	COG0477	Major facilitator Superfamily
At12D1_38760	COG2205	protein histidine kinase activity
At12D1_38770	COG0745	RESPONSE REGULATOR receiver
At12D1_38780	COG0671	phosphoesterase, PA-phosphatase related
At12D1_38880	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
At12D1_38890	COG0156	8-amino-7-oxononanoate synthase activity
At12D1_38900	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
At12D1_38910	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
At12D1_38920	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
At12D1_38950	COG2963	transposase activity
At12D1_38960	COG3436	PFAM IS66 Orf2 family protein
At12D1_38970	COG2433	Pfam Transposase IS66
At12D1_39000	COG1199	ATP-dependent helicase activity
At12D1_39000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
At12D1_39070	COG0697	spore germination
At12D1_39080	COG0673	inositol 2-dehydrogenase activity
At12D1_39120	COG0477	Major facilitator Superfamily
At12D1_39130	COG0642	Histidine kinase
At12D1_39140	COG0745	RESPONSE REGULATOR receiver
At12D1_39150	COG2194	sulfuric ester hydrolase activity
At12D1_39170	COG0583	DNA-binding transcription factor activity
At12D1_39180	COG4774	siderophore transport
At12D1_39210	COG1120	ATPase activity
At12D1_39230	COG3474	cytochrome
At12D1_39240	COG2137	regulation of response to DNA damage stimulus
At12D1_39250	COG3386	PFAM SMP-30 Gluconolaconase
At12D1_39270	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_39280	COG1129	ABC transporter
At12D1_39290	COG1879	ABC-type sugar transport system periplasmic component
At12D1_39300	COG4585	Histidine kinase
At12D1_39310	COG2197	response regulator
At12D1_39330	COG2133	pyrroloquinoline quinone binding
At12D1_39350	COG0500	methyltransferase
At12D1_39360	COG0564	pseudouridine synthase activity
At12D1_39390	COG3448	diguanylate cyclase activity
At12D1_39390	COG4175	Glycine betaine
At12D1_39400	COG4176	ABC-type proline glycine betaine transport system permease component
At12D1_39420	COG0784	Response regulator, receiver
At12D1_39420	COG4191	Histidine kinase
At12D1_39430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
At12D1_39440	COG0489	protein tyrosine kinase activity
At12D1_39440	COG3206	protein involved in exopolysaccharide biosynthesis
At12D1_39450	COG1210	Utp--glucose-1-phosphate uridylyltransferase
At12D1_39460	COG1215	transferase activity, transferring glycosyl groups
At12D1_39470	COG1215	transferase activity, transferring glycosyl groups
At12D1_39480	COG1215	transferase activity, transferring glycosyl groups
At12D1_39490	COG0438	transferase activity, transferring glycosyl groups
At12D1_39500	COG2273	Hydrolase Family 16
At12D1_39510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
At12D1_39520	COG2244	polysaccharide biosynthetic process
At12D1_39530	COG0463	Glycosyl transferase, family 2
At12D1_39540	COG2327	Polysaccharide pyruvyl transferase
At12D1_39550	COG1215	transferase activity, transferring glycosyl groups
At12D1_39590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
At12D1_39600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_39630	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At12D1_39630	COG0446	pyridine nucleotide-disulphide oxidoreductase
At12D1_39690	COG1523	belongs to the glycosyl hydrolase 13 family
At12D1_39700	COG0033	Phosphoglucomutase
At12D1_39710	COG0297	glycogen (starch) synthase activity
At12D1_39720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
At12D1_39730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
At12D1_39740	COG0058	SHG alpha-glucan phosphorylase activity
At12D1_39760	COG1794	racemase activity, acting on amino acids and derivatives
At12D1_39770	COG1522	sequence-specific DNA binding
At12D1_39790	COG2084	Dehydrogenase
At12D1_39800	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_39810	COG1063	alcohol dehydrogenase
At12D1_39830	COG4988	ABC transporter
At12D1_39840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
At12D1_39860	COG1294	oxidase, subunit
At12D1_39920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
At12D1_39930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
At12D1_40000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
At12D1_40010	COG0539	negative regulation of cytoplasmic translation
At12D1_40070	COG4221	oxidoreductase activity
At12D1_40090	COG0747	negative chemotaxis
At12D1_40100	COG0601	transmembrane transport
At12D1_40110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_40120	COG0444	Belongs to the ABC transporter superfamily
At12D1_40130	COG4608	Belongs to the ABC transporter superfamily
At12D1_40140	COG0246	Mannitol dehydrogenase
At12D1_40170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_40200	COG0411	ABC transporter
At12D1_40210	COG0410	ABC transporter
At12D1_40220	COG0559	Belongs to the binding-protein-dependent transport system permease family
At12D1_40260	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
At12D1_40270	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_40300	COG4993	Dehydrogenase
At12D1_40310	COG3685	Protein conserved in bacteria
At12D1_40330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_40330	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
At12D1_40370	COG0693	protein deglycase activity
At12D1_40410	COG0189	ligase activity
At12D1_40420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
At12D1_40430	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
At12D1_40450	COG0435	Glutathione S-transferase
At12D1_40460	COG0583	DNA-binding transcription factor activity
At12D1_40470	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_40480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_40490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_40500	COG1116	anion transmembrane transporter activity
At12D1_40520	COG1522	sequence-specific DNA binding
At12D1_40550	COG0784	Response regulator, receiver
At12D1_40570	COG3920	Histidine kinase
At12D1_40590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
At12D1_40620	COG0019	diaminopimelate decarboxylase activity
At12D1_40650	COG0527	aspartate kinase activity
At12D1_40670	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
At12D1_40680	COG2890	protein-(glutamine-N5) methyltransferase activity
At12D1_40700	COG0542	response to heat
At12D1_40710	COG0739	heme binding
At12D1_40710	COG1196	nuclear chromosome segregation
At12D1_40710	COG0741	lytic transglycosylase activity
At12D1_40780	COG0776	regulation of translation
At12D1_40810	COG5489	Protein of unknown function (DUF736)
At12D1_40840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
At12D1_40870	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
At12D1_40910	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
At12D1_40920	COG0006	proline dipeptidase activity
At12D1_40940	COG1476	TRANSCRIPTIONal
At12D1_41040	COG0739	heme binding
At12D1_41040	COG0741	lytic transglycosylase activity
At12D1_41040	COG1196	nuclear chromosome segregation
At12D1_41120	COG4962	Type ii secretion system protein e
At12D1_41130	COG3838	Conjugal transfer protein Trbc
At12D1_41150	COG3451	type IV secretory pathway VirB4
At12D1_41210	COG2948	multi-organism process
At12D1_41220	COG4584	PFAM Integrase catalytic
At12D1_41230	COG4372	Transposase
At12D1_41240	COG3436	PFAM IS66 Orf2 family protein
At12D1_41250	COG2963	transposase activity
At12D1_41260	COG3300	MHYT domain
At12D1_41260	COG5001	Diguanylate cyclase
At12D1_41300	COG3920	Histidine kinase
At12D1_41310	COG2390	Transcriptional regulator
At12D1_41310	COG4584	PFAM Integrase catalytic
At12D1_41320	COG2390	Transcriptional regulator
At12D1_41320	COG4584	PFAM Integrase catalytic
At12D1_41330	COG1484	DNA-dependent DNA replication
At12D1_41360	COG3620	sequence-specific DNA binding
At12D1_41370	COG3550	peptidyl-serine autophosphorylation
At12D1_41410	COG3300	MHYT domain
At12D1_41410	COG5001	Diguanylate cyclase
At12D1_41420	COG5001	Diguanylate cyclase
At12D1_41420	COG3300	MHYT domain
At12D1_41430	COG3706	GGDEF domain
At12D1_41430	COG4251	negative regulation of phosphorylation
At12D1_41430	COG5001	Diguanylate cyclase
At12D1_41430	COG2203	Gaf domain
At12D1_41450	COG0840	transmembrane signaling receptor activity
At12D1_41470	COG5001	Diguanylate cyclase
At12D1_41490	COG4584	PFAM Integrase catalytic
At12D1_41500	COG5001	Diguanylate cyclase
At12D1_41510	COG0745	RESPONSE REGULATOR receiver
At12D1_41520	COG5001	Diguanylate cyclase
At12D1_41530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
At12D1_41540	COG2200	EAL domain
At12D1_41540	COG2771	luxR family
At12D1_41580	COG3422	double-strand break repair
At12D1_41590	COG1376	ErfK ybiS ycfS ynhG family protein
At12D1_41690	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
At12D1_41700	COG0459	protein refolding
At12D1_41730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
At12D1_41750	COG0745	RESPONSE REGULATOR receiver
At12D1_41760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
At12D1_41770	COG0784	Response regulator, receiver
At12D1_41770	COG4191	Histidine kinase
At12D1_41800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
At12D1_41810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
At12D1_41830	COG1280	lysine exporter protein (LysE YggA)
At12D1_41860	COG1309	transcriptional regulator
At12D1_41870	COG4221	oxidoreductase activity
At12D1_41880	COG1902	pentaerythritol trinitrate reductase activity
At12D1_41890	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_41950	COG1278	Cold shock
At12D1_41980	COG0753	catalase activity
At12D1_42040	COG3920	Histidine kinase
At12D1_42090	COG1129	ABC transporter
At12D1_42100	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_42110	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_42160	COG0667	Aldo Keto reductase
At12D1_42190	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_42200	COG1129	ABC transporter
At12D1_42210	COG4213	ABC transporter substrate-binding protein
At12D1_42250	COG4608	Belongs to the ABC transporter superfamily
At12D1_42260	COG0444	Belongs to the ABC transporter superfamily
At12D1_42280	COG0601	transmembrane transport
At12D1_42290	COG0747	negative chemotaxis
At12D1_42330	COG0765	amino acid transport
At12D1_42340	COG4597	amino acid ABC transporter
At12D1_42350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_42370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
At12D1_42390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
At12D1_42430	COG0625	glutathione transferase activity
At12D1_42440	COG4221	oxidoreductase activity
At12D1_42520	COG0667	Aldo Keto reductase
At12D1_42530	COG0656	L-ascorbic acid biosynthetic process
At12D1_42540	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_42560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_42570	COG1126	abc transporter atp-binding protein
At12D1_42630	COG2376	Dihydroxyacetone kinase
At12D1_42640	COG1522	sequence-specific DNA binding
At12D1_42680	COG0431	NADPH-dependent FMN reductase
At12D1_42700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
At12D1_42720	COG4172	Belongs to the ABC transporter superfamily
At12D1_42730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_42770	COG0277	FAD linked oxidase domain protein
At12D1_42810	COG0778	Nitroreductase
At12D1_42870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
At12D1_42920	COG2318	DinB family
At12D1_42930	COG0583	DNA-binding transcription factor activity
At12D1_42960	COG1335	isochorismatase
At12D1_42980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
At12D1_43010	COG3842	ATPase activity
At12D1_43020	COG1176	ABC-type spermidine putrescine transport system, permease component I
At12D1_43030	COG1177	transmembrane transport
At12D1_43040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
At12D1_43060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
At12D1_43090	COG1120	ATPase activity
At12D1_43100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_43110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_43120	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
At12D1_43130	COG4774	siderophore transport
At12D1_43130	COG1629	transport
At12D1_43140	COG4702	Belongs to the UPF0303 family
At12D1_43180	COG1024	Enoyl-CoA hydratase
At12D1_43200	COG1653	transport
At12D1_43230	COG3842	ATPase activity
At12D1_43280	COG3474	cytochrome
At12D1_43290	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
At12D1_43300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
At12D1_43310	COG1845	cytochrome c oxidase, subunit III
At12D1_43370	COG1136	(ABC) transporter
At12D1_43370	COG0577	efflux transmembrane transporter activity
At12D1_43410	COG0745	RESPONSE REGULATOR receiver
At12D1_43480	COG3842	ATPase activity
At12D1_43500	COG1177	transmembrane transport
At12D1_43510	COG1176	ABC-type spermidine putrescine transport system, permease component I
At12D1_43540	COG1940	carbohydrate kinase activity
At12D1_43580	COG1069	ribulokinase activity
At12D1_43590	COG1349	DNA-binding transcription factor activity
At12D1_43600	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_43650	COG0395	ABC-type sugar transport system, permease component
At12D1_43670	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_43690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
At12D1_43700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
At12D1_43720	COG0477	Major facilitator Superfamily
At12D1_43800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
At12D1_43840	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_43850	COG0667	Aldo Keto reductase
At12D1_43860	COG0667	Aldo Keto reductase
At12D1_43910	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_43930	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
At12D1_43940	COG3938	Belongs to the proline racemase family
At12D1_43950	COG4176	ABC-type proline glycine betaine transport system permease component
At12D1_43970	COG3448	diguanylate cyclase activity
At12D1_43970	COG4175	Glycine betaine
At12D1_43990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_44000	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_44010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_44030	COG0047	phosphoribosylformylglycinamidine synthase activity
At12D1_44040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_44060	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At12D1_44060	COG0446	pyridine nucleotide-disulphide oxidoreductase
At12D1_44080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
At12D1_44110	COG1309	transcriptional regulator
At12D1_44140	COG1136	(ABC) transporter
At12D1_44170	COG1063	alcohol dehydrogenase
At12D1_44190	COG1879	ABC-type sugar transport system periplasmic component
At12D1_44210	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_44250	COG0477	Major facilitator Superfamily
At12D1_44460	COG3501	Rhs element vgr protein
At12D1_44530	COG3300	MHYT domain
At12D1_44530	COG5001	Diguanylate cyclase
At12D1_44580	COG1253	flavin adenine dinucleotide binding
At12D1_44610	COG3842	ATPase activity
At12D1_44620	COG0395	ABC-type sugar transport system, permease component
At12D1_44630	COG1175	transmembrane transport
At12D1_44660	COG0673	inositol 2-dehydrogenase activity
At12D1_44670	COG1609	Transcriptional regulator
At12D1_44700	COG0583	DNA-binding transcription factor activity
At12D1_44720	COG1879	ABC-type sugar transport system periplasmic component
At12D1_44730	COG1129	ABC transporter
At12D1_44740	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_44750	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_44760	COG1609	Transcriptional regulator
At12D1_44780	COG0673	inositol 2-dehydrogenase activity
At12D1_44900	COG0714	Associated with various cellular activities
At12D1_44910	COG3256	nitric oxide reductase
At12D1_44940	COG1845	cytochrome c oxidase, subunit III
At12D1_44970	COG0163	prenyltransferase activity
At12D1_44980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
At12D1_44990	COG3189	MarR family transcriptional regulator
At12D1_45080	COG4459	periplasmic nitrate reductase
At12D1_45110	COG0243	molybdopterin cofactor binding
At12D1_45130	COG3005	denitrification pathway
At12D1_45160	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_45170	COG3433	isochorismatase activity
At12D1_45170	COG1535	isochorismatase
At12D1_45180	COG1021	2,3-dihydroxybenzoate-AMP ligase
At12D1_45190	COG1169	isochorismate synthase
At12D1_45210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
At12D1_45210	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
At12D1_45220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
At12D1_45240	COG2375	cellular response to nickel ion
At12D1_45260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_45270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_45310	COG1629	transport
At12D1_45310	COG4774	siderophore transport
At12D1_45320	COG1960	acyl-CoA dehydrogenase activity
At12D1_45330	COG0583	DNA-binding transcription factor activity
At12D1_45340	COG1609	Transcriptional regulator
At12D1_45360	COG1176	ABC-type spermidine putrescine transport system, permease component I
At12D1_45400	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
At12D1_45410	COG0583	DNA-binding transcription factor activity
At12D1_45420	COG2814	Major facilitator Superfamily
At12D1_45430	COG1473	amidohydrolase
At12D1_45440	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
At12D1_45460	COG0747	negative chemotaxis
At12D1_45470	COG0601	transmembrane transport
At12D1_45490	COG0444	Belongs to the ABC transporter superfamily
At12D1_45500	COG4608	Belongs to the ABC transporter superfamily
At12D1_45510	COG0583	DNA-binding transcription factor activity
At12D1_45520	COG0747	negative chemotaxis
At12D1_45530	COG0601	transmembrane transport
At12D1_45540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_45550	COG0154	amidase activity
At12D1_45560	COG0693	protein deglycase activity
At12D1_45580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_45590	COG0601	transmembrane transport
At12D1_45610	COG1473	amidohydrolase
At12D1_45620	COG4172	Belongs to the ABC transporter superfamily
At12D1_45630	COG2390	Transcriptional regulator
At12D1_45650	COG1175	transmembrane transport
At12D1_45660	COG0395	ABC-type sugar transport system, permease component
At12D1_45710	COG1069	ribulokinase activity
At12D1_45760	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
At12D1_45800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
At12D1_45810	COG1414	Transcriptional regulator
At12D1_45820	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_45840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
At12D1_45850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
At12D1_45860	COG1121	(ABC) transporter
At12D1_45870	COG0803	Belongs to the bacterial solute-binding protein 9 family
At12D1_45890	COG1752	Esterase of the alpha-beta hydrolase superfamily
At12D1_45900	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
At12D1_45910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
At12D1_45920	COG3273	potassium ion transport
At12D1_45920	COG0471	metal ion transport
At12D1_45930	COG2827	Endonuclease containing a URI domain
At12D1_45940	COG1253	flavin adenine dinucleotide binding
At12D1_45950	COG1309	transcriptional regulator
At12D1_45990	COG1609	Transcriptional regulator
At12D1_46000	COG1070	Carbohydrate kinase
At12D1_46010	COG2115	Belongs to the xylose isomerase family
At12D1_46030	COG0778	Nitroreductase
At12D1_46040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
At12D1_46050	COG2011	ABC-type metal ion transport system permease component
At12D1_46070	COG3300	MHYT domain
At12D1_46070	COG5001	Diguanylate cyclase
At12D1_46110	COG0800	Aldolase
At12D1_46150	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
At12D1_46220	COG0523	cobalamin synthesis protein
At12D1_46240	COG1846	Transcriptional regulator
At12D1_46250	COG1609	Transcriptional regulator
At12D1_46260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At12D1_46280	COG3718	enzyme involved in inositol metabolism
At12D1_46300	COG3962	Belongs to the TPP enzyme family
At12D1_46310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_46340	COG0411	ABC transporter
At12D1_46370	COG0683	leucine binding
At12D1_46390	COG2207	Transcriptional regulator
At12D1_46410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_46430	COG0747	negative chemotaxis
At12D1_46440	COG4172	Belongs to the ABC transporter superfamily
At12D1_46480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
At12D1_46490	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
At12D1_46500	COG1126	abc transporter atp-binding protein
At12D1_46510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_46520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_46530	COG0765	amino acid transport
At12D1_46540	COG0765	amino acid transport
At12D1_46550	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
At12D1_46560	COG3485	protocatechuate 3,4-dioxygenase
At12D1_46570	COG3485	protocatechuate 3,4-dioxygenase
At12D1_46580	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
At12D1_46590	COG2267	carboxylic ester hydrolase activity
At12D1_46600	COG0583	DNA-binding transcription factor activity
At12D1_46630	COG1414	Transcriptional regulator
At12D1_46650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
At12D1_46660	COG0183	Belongs to the thiolase family
At12D1_46680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
At12D1_46690	COG1609	Transcriptional regulator
At12D1_46720	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_46730	COG0673	inositol 2-dehydrogenase activity
At12D1_46750	COG1609	Transcriptional regulator
At12D1_46760	COG0395	ABC-type sugar transport system, permease component
At12D1_46770	COG1175	transmembrane transport
At12D1_46780	COG3842	ATPase activity
At12D1_46800	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
At12D1_46840	COG2814	Major facilitator Superfamily
At12D1_46850	COG4774	siderophore transport
At12D1_46860	COG3712	iron ion homeostasis
At12D1_46880	COG1940	carbohydrate kinase activity
At12D1_46890	COG0584	glycerophosphoryl diester phosphodiesterase
At12D1_46900	COG0300	oxidoreductase activity
At12D1_46970	COG3210	domain, Protein
At12D1_46970	COG3210	domain, Protein
At12D1_47010	COG2963	transposase activity
At12D1_47020	COG3436	PFAM IS66 Orf2 family protein
At12D1_47030	COG2433	Pfam Transposase IS66
At12D1_47090	COG0385	Bile acid
At12D1_47100	COG0667	Aldo Keto reductase
At12D1_47110	COG0583	DNA-binding transcription factor activity
At12D1_47130	COG2942	2-epimerase
At12D1_47140	COG1132	(ABC) transporter
At12D1_47160	COG0297	glycogen (starch) synthase activity
At12D1_47230	COG0463	Glycosyl transferase, family 2
At12D1_47270	COG0572	uridine kinase
At12D1_47320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_47330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_47340	COG1120	ATPase activity
At12D1_47350	COG4774	siderophore transport
At12D1_47390	COG1609	Transcriptional regulator
At12D1_47400	COG0404	The glycine cleavage system catalyzes the degradation of glycine
At12D1_47400	COG0446	pyridine nucleotide-disulphide oxidoreductase
At12D1_47430	COG0395	ABC-type sugar transport system, permease component
At12D1_47440	COG3842	ATPase activity
At12D1_47450	COG4608	Belongs to the ABC transporter superfamily
At12D1_47460	COG0444	Belongs to the ABC transporter superfamily
At12D1_47470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_47480	COG0601	transmembrane transport
At12D1_47490	COG2186	Transcriptional regulator
At12D1_47510	COG0747	negative chemotaxis
At12D1_47530	COG3300	MHYT domain
At12D1_47530	COG5001	Diguanylate cyclase
At12D1_47540	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_47560	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
At12D1_47580	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
At12D1_47590	COG0306	phosphate transporter
At12D1_47600	COG1392	Phosphate transport regulator
At12D1_47640	COG1566	PFAM secretion protein HlyD family protein
At12D1_47650	COG0745	RESPONSE REGULATOR receiver
At12D1_47660	COG2205	protein histidine kinase activity
At12D1_47690	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
At12D1_47710	COG2207	Transcriptional regulator
At12D1_47720	COG4774	siderophore transport
At12D1_47740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_47750	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
At12D1_47760	COG1120	ATPase activity
At12D1_47810	COG0559	Belongs to the binding-protein-dependent transport system permease family
At12D1_47850	COG1012	belongs to the aldehyde dehydrogenase family
At12D1_47860	COG0583	DNA-binding transcription factor activity
At12D1_47880	COG3119	arylsulfatase activity
At12D1_47890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
At12D1_47900	COG3842	ATPase activity
At12D1_47910	COG0165	Argininosuccinate lyase
At12D1_47920	COG0395	ABC-type sugar transport system, permease component
At12D1_47930	COG1175	transmembrane transport
At12D1_47940	COG2182	Extracellular solute-binding protein
At12D1_47950	COG1940	carbohydrate kinase activity
At12D1_48000	COG1486	melibiose metabolic process
At12D1_48010	COG0747	negative chemotaxis
At12D1_48020	COG0601	transmembrane transport
At12D1_48030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_48040	COG4172	Belongs to the ABC transporter superfamily
At12D1_48050	COG1486	melibiose metabolic process
At12D1_48060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
At12D1_48070	COG1129	ABC transporter
At12D1_48070	COG0842	Transport permease protein
At12D1_48080	COG0842	Transport permease protein
At12D1_48110	COG0784	Response regulator, receiver
At12D1_48120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
At12D1_48140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_48150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
At12D1_48180	COG0765	amino acid transport
At12D1_48200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
At12D1_48220	COG3938	Belongs to the proline racemase family
At12D1_48250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
At12D1_48270	COG0765	amino acid transport
At12D1_48290	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
At12D1_48320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
At12D1_48360	COG3383	formate dehydrogenase (NAD+) activity
At12D1_48390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
At12D1_48410	COG2186	Transcriptional regulator
At12D1_48420	COG0747	negative chemotaxis
At12D1_48430	COG0601	transmembrane transport
At12D1_48440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_48450	COG4172	Belongs to the ABC transporter superfamily
At12D1_48460	COG4948	Mandelate Racemase Muconate Lactonizing
At12D1_48480	COG2186	Transcriptional regulator
At12D1_48490	COG0747	negative chemotaxis
At12D1_48500	COG0601	transmembrane transport
At12D1_48520	COG0405	Gamma-glutamyltransferase
At12D1_48540	COG0483	inositol monophosphate 1-phosphatase activity
At12D1_48560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
At12D1_48610	COG3237	CsbD-like
At12D1_48630	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
At12D1_48640	COG3181	Tripartite tricarboxylate transporter family receptor
At12D1_48650	COG5265	(ABC) transporter
At12D1_48670	COG0488	(ABC) transporter
At12D1_48720	COG1049	propionate catabolic process, 2-methylcitrate cycle
At12D1_48730	COG0110	maltose O-acetyltransferase activity
At12D1_48750	COG1063	alcohol dehydrogenase
At12D1_48760	COG3284	Transcriptional regulator
At12D1_48800	COG1129	ABC transporter
At12D1_48810	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_48820	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_48830	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_48840	COG0572	uridine kinase
At12D1_48850	COG1082	Xylose isomerase domain protein TIM barrel
At12D1_48900	COG4178	(ABC) transporter
At12D1_48960	COG0640	Transcriptional regulator
At12D1_49000	COG1192	Involved in chromosome partitioning
At12D1_49010	COG1475	DNA binding
At12D1_49020	COG0640	Transcriptional regulator
At12D1_49030	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
At12D1_49130	COG0583	DNA-binding transcription factor activity
At12D1_49160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
At12D1_49170	COG1116	anion transmembrane transporter activity
At12D1_49180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_49230	COG1028	Short-chain dehydrogenase reductase Sdr
At12D1_49240	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
At12D1_49290	COG1172	Belongs to the binding-protein-dependent transport system permease family
At12D1_49300	COG1129	ABC transporter
At12D1_49340	COG0747	negative chemotaxis
At12D1_49350	COG4172	Belongs to the ABC transporter superfamily
At12D1_49370	COG0601	transmembrane transport
At12D1_49410	COG0583	DNA-binding transcription factor activity
At12D1_49420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
At12D1_49440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
At12D1_49460	COG0745	RESPONSE REGULATOR receiver
At12D1_49470	COG2205	protein histidine kinase activity
At12D1_49520	COG3293	Transposase
At12D1_49560	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
At12D1_49660	COG1475	DNA binding
At12D1_49720	COG4974	Belongs to the 'phage' integrase family
At12D1_49730	COG4974	Belongs to the 'phage' integrase family
At12D1_49740	COG4974	Belongs to the 'phage' integrase family
At12D1_49760	COG0697	spore germination
At12D1_49800	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
At12D1_49810	COG5489	Protein of unknown function (DUF736)
At12D1_49930	COG0583	DNA-binding transcription factor activity
At12D1_49950	COG0765	amino acid transport
At12D1_50030	COG1283	sodium-dependent phosphate transmembrane transporter activity
At12D1_50050	COG0747	negative chemotaxis
At12D1_50080	COG0601	transmembrane transport
At12D1_50090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_50100	COG0584	glycerophosphoryl diester phosphodiesterase
At12D1_50150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
At12D1_50160	COG0601	transmembrane transport
At12D1_50190	COG0444	Belongs to the ABC transporter superfamily
At12D1_50200	COG0747	negative chemotaxis
At12D1_50220	COG2390	Transcriptional regulator
At12D1_50320	COG0145	ligase activity
At12D1_50340	COG0583	DNA-binding transcription factor activity
At12D1_50440	COG3701	Conjugal transfer protein
At12D1_50450	COG3846	protein secretion by the type IV secretion system
At12D1_50470	COG5314	conjugation
At12D1_50480	COG3451	type IV secretory pathway VirB4
At12D1_50510	COG4962	Type ii secretion system protein e