locus-tag	class	description
CG010_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG010_000010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG010_000015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CG010_000020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CG010_000025	COG1420	regulation of RNA biosynthetic process
CG010_000030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CG010_000035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG010_000040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CG010_000050	COG1137	ATPase activity
CG010_000055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CG010_000065	COG0616	signal peptide processing
CG010_000070	COG0776	regulation of translation
CG010_000080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CG010_000085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG010_000090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CG010_000105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CG010_000110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CG010_000115	COG0728	peptidoglycan biosynthetic process
CG010_000125	COG0180	Tryptophanyl-tRNA synthetase
CG010_000135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CG010_000140	COG1214	PFAM Peptidase M22, glycoprotease
CG010_000160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG010_000165	COG1702	phosphate starvation-inducible protein PhoH
CG010_000170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CG010_000180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CG010_000185	COG1396	sequence-specific DNA binding
CG010_000190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CG010_000195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CG010_000200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_000210	COG0242	peptide deformylase activity
CG010_000215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CG010_000220	COG0101	tRNA pseudouridine synthase activity
CG010_000230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG010_000235	COG2171	N-acyltransferase activity
CG010_000245	COG0840	transmembrane signaling receptor activity
CG010_000250	COG1957	nucleoside hydrolase
CG010_000255	COG0071	Belongs to the small heat shock protein (HSP20) family
CG010_000280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CG010_000290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CG010_000295	COG0706	membrane insertase activity
CG010_000300	COG0594	ribonuclease P activity
CG010_000305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CG010_000310	COG0840	transmembrane signaling receptor activity
CG010_000330	COG2226	methyltransferase
CG010_000335	COG3842	ATPase activity
CG010_000340	COG1175	transmembrane transport
CG010_000345	COG0395	ABC-type sugar transport system, permease component
CG010_000360	COG0427	acetyl-CoA hydrolase
CG010_000370	COG3938	Belongs to the proline racemase family
CG010_000375	COG0418	dihydroorotase activity
CG010_000380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CG010_000400	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CG010_000405	COG0166	Belongs to the GPI family
CG010_000410	COG0318	PFAM AMP-dependent synthetase and ligase
CG010_000415	COG3842	ATPase activity
CG010_000420	COG1840	ABC-type Fe3 transport system, periplasmic component
CG010_000425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CG010_000430	COG4774	siderophore transport
CG010_000475	COG2326	polyphosphate kinase activity
CG010_000480	COG5002	protein histidine kinase activity
CG010_000485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CG010_000490	COG0573	inorganic phosphate transmembrane transporter activity
CG010_000500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CG010_000505	COG0704	Plays a role in the regulation of phosphate uptake
CG010_000510	COG0745	RESPONSE REGULATOR receiver
CG010_000525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CG010_000530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CG010_000535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CG010_000540	COG2967	ApaG domain
CG010_000550	COG0717	Belongs to the dCTP deaminase family
CG010_000560	COG0582	viral genome integration into host DNA
CG010_000585	COG0419	ATPase involved in DNA repair
CG010_000605	COG1396	sequence-specific DNA binding
CG010_000645	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
CG010_000650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CG010_000700	COG0167	dihydroorotate dehydrogenase activity
CG010_000740	COG1959	2 iron, 2 sulfur cluster binding
CG010_000745	COG1201	RNA secondary structure unwinding
CG010_000780	COG1960	acyl-CoA dehydrogenase activity
CG010_000785	COG0183	Belongs to the thiolase family
CG010_000795	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG010_000795	COG1024	Enoyl-CoA hydratase
CG010_000825	COG1320	monovalent cation:proton antiporter activity
CG010_000830	COG2212	antiporter activity
CG010_000835	COG1863	multisubunit Na H antiporter MnhE subunit
CG010_000840	COG0651	ATP synthesis coupled electron transport
CG010_000845	COG1006	Multisubunit Na H antiporter MnhC subunit
CG010_000850	COG2111	Na H antiporter
CG010_000850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CG010_000860	COG0840	transmembrane signaling receptor activity
CG010_000875	COG0643	Histidine kinase
CG010_000875	COG2198	Histidine kinase
CG010_000880	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CG010_000885	COG2201	protein-glutamate methylesterase activity
CG010_000890	COG0745	RESPONSE REGULATOR receiver
CG010_000895	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CG010_000905	COG1766	The M ring may be actively involved in energy transduction
CG010_000910	COG2771	luxR family
CG010_000920	COG2972	Histidine kinase
CG010_000920	COG0840	transmembrane signaling receptor activity
CG010_000925	COG0784	Response regulator, receiver
CG010_000925	COG2198	Histidine kinase
CG010_000925	COG2205	protein histidine kinase activity
CG010_000930	COG1970	mechanosensitive ion channel activity
CG010_000935	COG0436	Aminotransferase
CG010_000950	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CG010_000955	COG0424	maF-like protein
CG010_000960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CG010_000970	COG5328	Belongs to the UPF0262 family
CG010_000975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CG010_000985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CG010_001005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CG010_001020	COG1338	Plays a role in the flagellum-specific transport system
CG010_001030	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CG010_001040	COG1706	bacterial-type flagellum-dependent cell motility
CG010_001045	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CG010_001050	COG4786	Flagellar basal body rod
CG010_001055	COG1677	Flagellar hook-basal body complex protein FliE
CG010_001060	COG1558	bacterial-type flagellum-dependent cell motility
CG010_001065	COG1815	bacterial-type flagellum-dependent cell motility
CG010_001075	COG1157	protein secretion by the type III secretion system
CG010_001080	COG4786	Flagellar basal body rod
CG010_001090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CG010_001095	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG010_001100	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG010_001105	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CG010_001110	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG010_001135	COG1360	Flagellar Motor Protein
CG010_001180	COG5443	negative regulation of bacterial-type flagellum assembly
CG010_001185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CG010_001195	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CG010_001235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CG010_001240	COG1609	Transcriptional regulator
CG010_001245	COG1653	transport
CG010_001250	COG1175	transmembrane transport
CG010_001255	COG0395	ABC-type sugar transport system, permease component
CG010_001260	COG0366	Alpha amylase catalytic
CG010_001265	COG3842	ATPase activity
CG010_001280	COG0129	dihydroxy-acid dehydratase activity
CG010_001285	COG0363	glucosamine-6-phosphate deaminase activity
CG010_001290	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CG010_001295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_001305	COG2081	HI0933 family
CG010_001325	COG2224	Isocitrate lyase
CG010_001340	COG3842	ATPase activity
CG010_001345	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_001350	COG1177	transmembrane transport
CG010_001360	COG2205	protein histidine kinase activity
CG010_001370	COG0248	Ppx GppA phosphatase
CG010_001375	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CG010_001380	COG0477	Major facilitator Superfamily
CG010_001415	COG0521	Mo-molybdopterin cofactor biosynthetic process
CG010_001420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CG010_001430	COG0142	geranyltranstransferase activity
CG010_001455	COG0752	glycyl-tRNA synthetase alpha subunit
CG010_001465	COG1704	LemA family
CG010_001470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CG010_001480	COG0751	glycine-tRNA ligase activity
CG010_001490	COG1683	Conserved Protein
CG010_001495	COG0840	transmembrane signaling receptor activity
CG010_001505	COG0151	Belongs to the GarS family
CG010_001510	COG2183	response to ionizing radiation
CG010_001515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG010_001540	COG0583	DNA-binding transcription factor activity
CG010_001560	COG0306	phosphate transporter
CG010_001575	COG0561	phosphatase activity
CG010_001580	COG0438	transferase activity, transferring glycosyl groups
CG010_001585	COG2186	Transcriptional regulator
CG010_001600	COG0583	DNA-binding transcription factor activity
CG010_001605	COG0277	FAD linked oxidase domain protein
CG010_001615	COG0277	FAD linked oxidase domain protein
CG010_001620	COG0247	lactate metabolic process
CG010_001635	COG1376	ErfK ybiS ycfS ynhG family protein
CG010_001640	COG2818	Glycosylase
CG010_001650	COG2855	membrane
CG010_001655	COG0583	DNA-binding transcription factor activity
CG010_001685	COG0124	histidyl-tRNA synthetase
CG010_001695	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CG010_001700	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CG010_001705	COG2259	Doxx family
CG010_001715	COG0459	protein refolding
CG010_001720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CG010_001730	COG0196	riboflavin kinase activity
CG010_001735	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CG010_001745	COG0590	tRNA wobble adenosine to inosine editing
CG010_001750	COG1187	pseudouridine synthase activity
CG010_001755	COG0742	ribosomal rna small subunit methyltransferase
CG010_001765	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG010_001780	COG0312	modulator of DNA gyrase
CG010_001785	COG0483	inositol monophosphate 1-phosphatase activity
CG010_001795	COG1519	Transferase
CG010_001805	COG1663	tetraacyldisaccharide 4'-kinase activity
CG010_001815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CG010_001820	COG0745	RESPONSE REGULATOR receiver
CG010_001825	COG3300	MHYT domain
CG010_001825	COG5001	Diguanylate cyclase
CG010_001835	COG3386	PFAM SMP-30 Gluconolaconase
CG010_001840	COG0800	Aldolase
CG010_001845	COG3734	2-keto-3-deoxy-galactonokinase
CG010_001850	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_001855	COG1414	Transcriptional regulator
CG010_001860	COG2197	response regulator
CG010_001875	COG0598	Magnesium transport protein CorA
CG010_001880	COG3158	transport of potassium into the cell
CG010_001895	COG0356	it plays a direct role in the translocation of protons across the membrane
CG010_001905	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG010_001910	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CG010_001925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CG010_001945	COG0009	L-threonylcarbamoyladenylate synthase
CG010_001955	COG4638	Rieske (2fe-2S)
CG010_001980	COG1960	acyl-CoA dehydrogenase activity
CG010_001995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CG010_002000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CG010_002005	COG0840	transmembrane signaling receptor activity
CG010_002015	COG1522	sequence-specific DNA binding
CG010_002040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CG010_002045	COG1741	Belongs to the pirin family
CG010_002050	COG1722	exodeoxyribonuclease VII activity
CG010_002055	COG0123	including yeast histone deacetylase and acetoin utilization protein
CG010_002060	COG1268	BioY protein
CG010_002065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CG010_002070	COG1122	ATPase activity
CG010_002075	COG3214	Protein conserved in bacteria
CG010_002085	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CG010_002105	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CG010_002120	COG0259	pyridoxamine-phosphate oxidase activity
CG010_002150	COG0312	modulator of DNA gyrase
CG010_002165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG010_002170	COG0109	protoheme IX farnesyltransferase activity
CG010_002180	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CG010_002195	COG3346	SURF1 family
CG010_002200	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CG010_002205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CG010_002210	COG0328	RNA-DNA hybrid ribonuclease activity
CG010_002220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CG010_002220	COG0678	peroxiredoxin activity
CG010_002230	COG1678	Uncharacterized ACR, COG1678
CG010_002235	COG3237	CsbD-like
CG010_002245	COG3300	MHYT domain
CG010_002245	COG5001	Diguanylate cyclase
CG010_002250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CG010_002255	COG0612	Peptidase, M16
CG010_002280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG010_002285	COG1802	Transcriptional regulator
CG010_002305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CG010_002315	COG3609	addiction module antidote protein, CC2985 family
CG010_002320	COG3668	Plasmid stabilization system
CG010_002330	COG1194	a g-specific adenine glycosylase
CG010_002345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CG010_002350	COG1196	nuclear chromosome segregation
CG010_002355	COG2514	catechol 2,3-dioxygenase activity
CG010_002360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CG010_002360	COG0574	Belongs to the PEP-utilizing enzyme family
CG010_002395	COG0579	oxidoreductase
CG010_002420	COG2895	sulfate adenylyltransferase (ATP) activity
CG010_002425	COG0175	sulfate reduction
CG010_002430	COG0175	sulfate reduction
CG010_002435	COG1959	2 iron, 2 sulfur cluster binding
CG010_002440	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CG010_002445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CG010_002450	COG4208	sulfate ABC transporter
CG010_002455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG010_002470	COG2203	Gaf domain
CG010_002470	COG2199	diguanylate cyclase activity
CG010_002470	COG2200	EAL domain
CG010_002480	COG1309	transcriptional regulator
CG010_002485	COG1012	belongs to the aldehyde dehydrogenase family
CG010_002495	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CG010_002525	COG0625	glutathione transferase activity
CG010_002535	COG0477	Major facilitator Superfamily
CG010_002545	COG3657	addiction module killer protein
CG010_002555	COG1793	dna ligase
CG010_002575	COG1376	ErfK ybiS ycfS ynhG family protein
CG010_002580	COG1376	ErfK ybiS ycfS ynhG family protein
CG010_002585	COG1846	Transcriptional regulator
CG010_002590	COG1764	response to oxidative stress
CG010_002605	COG0488	(ABC) transporter
CG010_002640	COG4221	oxidoreductase activity
CG010_002655	COG0433	COG0433 Predicted ATPase
CG010_002670	COG1733	regulation of RNA biosynthetic process
CG010_002675	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CG010_002690	COG0656	L-ascorbic acid biosynthetic process
CG010_002695	COG3781	membrane
CG010_002700	COG2378	regulation of single-species biofilm formation
CG010_002710	COG4106	trans-aconitate 2-methyltransferase activity
CG010_002715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG010_002720	COG0840	transmembrane signaling receptor activity
CG010_002740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG010_002760	COG3909	cytochrome
CG010_002765	COG2010	Cytochrome c
CG010_002800	COG0789	Transcriptional regulator
CG010_002825	COG0517	IMP dehydrogenase activity
CG010_002825	COG4175	Glycine betaine
CG010_002830	COG4176	ABC-type proline glycine betaine transport system permease component
CG010_002870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG010_002870	COG2169	Transcriptional regulator
CG010_002880	COG2514	catechol 2,3-dioxygenase activity
CG010_002905	COG1272	protein, Hemolysin III
CG010_002915	COG1280	lysine exporter protein (LysE YggA)
CG010_002920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG010_002930	COG2111	Na H antiporter
CG010_002935	COG1006	Multisubunit Na H antiporter MnhC subunit
CG010_002950	COG2212	antiporter activity
CG010_002955	COG1320	monovalent cation:proton antiporter activity
CG010_002960	COG4957	zinc ion binding
CG010_002975	COG2166	iron-sulfur cluster assembly
CG010_002985	COG2205	protein histidine kinase activity
CG010_003035	COG0583	DNA-binding transcription factor activity
CG010_003040	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG010_003045	COG2983	Belongs to the UPF0260 family
CG010_003060	COG2217	Heavy metal translocating P-type atpase
CG010_003090	COG2814	Major facilitator Superfamily
CG010_003100	COG1621	beta-fructofuranosidase activity
CG010_003105	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CG010_003160	COG4695	Portal protein
CG010_003250	COG0745	RESPONSE REGULATOR receiver
CG010_003255	COG5002	protein histidine kinase activity
CG010_003265	COG4235	cytochrome complex assembly
CG010_003270	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CG010_003275	COG1138	Cytochrome C-type biogenesis protein
CG010_003280	COG3088	subunit of a heme lyase
CG010_003285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG010_003290	COG0745	RESPONSE REGULATOR receiver
CG010_003295	COG2205	protein histidine kinase activity
CG010_003300	COG3011	Protein conserved in bacteria
CG010_003305	COG3713	MltA-interacting MipA family protein
CG010_003310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CG010_003320	COG2205	protein histidine kinase activity
CG010_003320	COG2202	Pas domain
CG010_003330	COG0308	aminopeptidase N
CG010_003335	COG0697	spore germination
CG010_003355	COG0443	Heat shock 70 kDa protein
CG010_003360	COG5001	Diguanylate cyclase
CG010_003360	COG3300	MHYT domain
CG010_003365	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_003390	COG0604	alcohol dehydrogenase
CG010_003395	COG1733	regulation of RNA biosynthetic process
CG010_003400	COG1968	undecaprenyl-diphosphatase activity
CG010_003405	COG2239	Acts as a magnesium transporter
CG010_003410	COG2814	Major facilitator Superfamily
CG010_003435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CG010_003460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG010_003505	COG0741	lytic transglycosylase activity
CG010_003515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_003520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CG010_003525	COG0840	transmembrane signaling receptor activity
CG010_003535	COG1758	RNA polymerase activity
CG010_003555	COG0736	holo-[acyl-carrier-protein] synthase activity
CG010_003560	COG0681	Belongs to the peptidase S26 family
CG010_003565	COG0571	ribonuclease III activity
CG010_003570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CG010_003580	COG0784	Response regulator, receiver
CG010_003585	COG1381	Involved in DNA repair and RecF pathway recombination
CG010_003595	COG2226	methyltransferase
CG010_003605	COG1418	mRNA catabolic process
CG010_003615	COG0346	lactoylglutathione lyase activity
CG010_003625	COG1116	anion transmembrane transporter activity
CG010_003630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_003635	COG3443	Belongs to the bacterial solute-binding protein 9 family
CG010_003640	COG0668	transmembrane transport
CG010_003650	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CG010_003680	COG1742	UPF0060 membrane protein
CG010_003690	COG3706	GGDEF domain
CG010_003690	COG0745	RESPONSE REGULATOR receiver
CG010_003695	COG1183	phosphatidylcholine synthase activity
CG010_003700	COG0688	phosphatidylethanolamine metabolic process
CG010_003705	COG5265	(ABC) transporter
CG010_003745	COG2852	Protein conserved in bacteria
CG010_003750	COG0215	cysteine-tRNA ligase activity
CG010_003755	COG4221	oxidoreductase activity
CG010_003760	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CG010_003765	COG1286	toxin biosynthetic process
CG010_003785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG010_003795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CG010_003805	COG0305	Participates in initiation and elongation during chromosome replication
CG010_003830	COG0359	binds to the 23S rRNA
CG010_003840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CG010_003845	COG0360	Binds together with S18 to 16S ribosomal RNA
CG010_003860	COG0667	Aldo Keto reductase
CG010_003865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CG010_003875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG010_003880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG010_003890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CG010_003895	COG1561	YicC-like family, N-terminal region
CG010_003900	COG0194	GDP metabolic process
CG010_003915	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CG010_003920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CG010_003930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CG010_003945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG010_003965	COG3706	GGDEF domain
CG010_003965	COG2203	Gaf domain
CG010_003965	COG4251	negative regulation of phosphorylation
CG010_003965	COG5001	Diguanylate cyclase
CG010_003970	COG3300	MHYT domain
CG010_003970	COG5001	Diguanylate cyclase
CG010_003975	COG4191	Histidine kinase
CG010_003980	COG4566	intracellular signal transduction
CG010_003990	COG0488	(ABC) transporter
CG010_003995	COG3706	GGDEF domain
CG010_004005	COG0105	UTP biosynthetic process
CG010_004025	COG0314	molybdopterin synthase activity
CG010_004035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CG010_004040	COG0322	excinuclease ABC activity
CG010_004045	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_004070	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CG010_004075	COG0243	molybdopterin cofactor binding
CG010_004090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CG010_004095	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CG010_004105	COG0628	permease
CG010_004115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CG010_004120	COG0248	Ppx GppA phosphatase
CG010_004145	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CG010_004155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CG010_004160	COG0477	Major facilitator Superfamily
CG010_004165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CG010_004175	COG0840	transmembrane signaling receptor activity
CG010_004180	COG0659	secondary active sulfate transmembrane transporter activity
CG010_004190	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG010_004195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CG010_004205	COG0113	porphobilinogen synthase activity
CG010_004225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG010_004230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CG010_004235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG010_004235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CG010_004245	COG1280	lysine exporter protein (LysE YggA)
CG010_004250	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CG010_004255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG010_004260	COG2814	Major facilitator Superfamily
CG010_004265	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CG010_004285	COG0416	fatty acid biosynthetic process
CG010_004290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG010_004295	COG0776	regulation of translation
CG010_004330	COG0601	transmembrane transport
CG010_004335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_004340	COG0444	Belongs to the ABC transporter superfamily
CG010_004350	COG0747	negative chemotaxis
CG010_004360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CG010_004365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CG010_004375	COG0745	RESPONSE REGULATOR receiver
CG010_004375	COG3706	GGDEF domain
CG010_004380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CG010_004385	COG0583	DNA-binding transcription factor activity
CG010_004390	COG0737	Belongs to the 5'-nucleotidase family
CG010_004410	COG2897	thiosulfate sulfurtransferase activity
CG010_004425	COG0415	Belongs to the DNA photolyase family
CG010_004435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG010_004465	COG3932	Exopolysaccharide synthesis, ExoD
CG010_004470	COG1238	metal cluster binding
CG010_004545	COG1612	heme a metabolic process
CG010_004555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CG010_004560	COG0010	Belongs to the arginase family
CG010_004565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CG010_004570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CG010_004585	COG1832	CoA-binding protein
CG010_004615	COG2124	cytochrome p450
CG010_004620	COG2199	diguanylate cyclase activity
CG010_004625	COG0740	serine-type endopeptidase activity
CG010_004630	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CG010_004640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CG010_004650	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CG010_004670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG010_004675	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG010_004680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG010_004690	COG0649	NAD binding
CG010_004700	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CG010_004705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CG010_004715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CG010_004720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CG010_004730	COG0713	ATP synthesis coupled electron transport
CG010_004745	COG1007	ATP synthesis coupled electron transport
CG010_004750	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CG010_004750	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CG010_004770	COG0442	prolyl-tRNA aminoacylation
CG010_004780	COG1136	(ABC) transporter
CG010_004790	COG0587	DNA-directed DNA polymerase activity
CG010_004800	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG010_004820	COG0784	Response regulator, receiver
CG010_004825	COG3706	GGDEF domain
CG010_004825	COG0745	RESPONSE REGULATOR receiver
CG010_004835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CG010_004840	COG0477	Major facilitator Superfamily
CG010_004855	COG0557	exoribonuclease II activity
CG010_004860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CG010_004870	COG0758	DNA mediated transformation
CG010_004875	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CG010_004885	COG0540	Belongs to the ATCase OTCase family
CG010_004900	COG1960	acyl-CoA dehydrogenase activity
CG010_004905	COG0456	acetyltransferase
CG010_004920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CG010_004925	COG2824	Alkylphosphonate utilization operon protein PhnA
CG010_004930	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CG010_004935	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG010_004940	COG0154	amidase activity
CG010_004945	COG0456	acetyltransferase
CG010_004950	COG3811	Belongs to the UPF0386 family
CG010_004965	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CG010_004995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CG010_005000	COG0439	Biotin carboxylase
CG010_005005	COG0511	ligase activity, forming carbon-carbon bonds
CG010_005010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG010_005020	COG0436	Aminotransferase
CG010_005040	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_005050	COG1530	ribonuclease E activity
CG010_005065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG010_005085	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CG010_005090	COG0384	phenazine biosynthesis protein PhzF
CG010_005110	COG0633	Ferredoxin
CG010_005120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CG010_005125	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CG010_005130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CG010_005140	COG3768	UPF0283 membrane protein
CG010_005145	COG3106	COG3106 Predicted ATPase
CG010_005155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CG010_005175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CG010_005210	COG0537	adenosine 5'-monophosphoramidase activity
CG010_005235	COG0052	Belongs to the universal ribosomal protein uS2 family
CG010_005240	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CG010_005245	COG0528	UMP kinase activity
CG010_005250	COG0233	cytoplasmic translational termination
CG010_005255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CG010_005260	COG0575	Belongs to the CDS family
CG010_005265	COG0750	zinc metalloprotease
CG010_005270	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG010_005275	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG010_005280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG010_005285	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG010_005290	COG3494	Protein of unknown function (DUF1009)
CG010_005295	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CG010_005300	COG2186	Transcriptional regulator
CG010_005310	COG0765	amino acid transport
CG010_005325	COG0372	Belongs to the citrate synthase family
CG010_005340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CG010_005370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CG010_005375	COG1459	type II secretion system
CG010_005430	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CG010_005435	COG0148	phosphopyruvate hydratase activity
CG010_005445	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CG010_005450	COG0022	dehydrogenase e1 component
CG010_005450	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG010_005455	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG010_005465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CG010_005475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CG010_005480	COG0697	spore germination
CG010_005500	COG2867	negative regulation of translational initiation
CG010_005505	COG1546	Belongs to the CinA family
CG010_005510	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CG010_005510	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CG010_005520	COG3852	Histidine kinase
CG010_005525	COG2204	response regulator
CG010_005530	COG5000	phosphorelay sensor kinase activity
CG010_005535	COG2204	response regulator
CG010_005540	COG0569	domain protein
CG010_005545	COG1923	regulation of RNA biosynthetic process
CG010_005550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CG010_005555	COG3956	TIGRFAM MazG family protein
CG010_005570	COG1648	precorrin-2 dehydrogenase activity
CG010_005570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG010_005610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG010_005610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CG010_005615	COG0509	glycine decarboxylation via glycine cleavage system
CG010_005620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG010_005645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CG010_005650	COG0564	pseudouridine synthase activity
CG010_005670	COG0251	oxidation-reduction process
CG010_005675	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CG010_005685	COG1671	Belongs to the UPF0178 family
CG010_005700	COG0450	alkyl hydroperoxide reductase
CG010_005705	COG0625	glutathione transferase activity
CG010_005715	COG2801	Transposase and inactivated derivatives
CG010_005720	COG0431	NADPH-dependent FMN reductase
CG010_005730	COG0798	PFAM Bile acid sodium symporter
CG010_005735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG010_005750	COG0321	lipoyl(octanoyl) transferase activity
CG010_005750	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CG010_005755	COG0084	hydrolase, TatD family'
CG010_005760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG010_005770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CG010_005825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CG010_005830	COG2095	MarC family integral membrane protein
CG010_005845	COG0629	single-stranded DNA binding
CG010_005850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CG010_005860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CG010_005880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG010_005885	COG1121	(ABC) transporter
CG010_005890	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CG010_005905	COG0667	Aldo Keto reductase
CG010_005915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CG010_006000	COG2239	Acts as a magnesium transporter
CG010_006005	COG0243	molybdopterin cofactor binding
CG010_006015	COG0242	peptide deformylase activity
CG010_006030	COG2205	protein histidine kinase activity
CG010_006030	COG2202	Pas domain
CG010_006045	COG0321	lipoyl(octanoyl) transferase activity
CG010_006050	COG1064	alcohol dehydrogenase
CG010_006100	COG2124	cytochrome p450
CG010_006125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG010_006130	COG0626	cystathionine gamma-synthase activity
CG010_006135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_006140	COG4597	amino acid ABC transporter
CG010_006145	COG0765	amino acid transport
CG010_006150	COG1126	abc transporter atp-binding protein
CG010_006170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CG010_006185	COG0436	Aminotransferase
CG010_006215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG010_006225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG010_006230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG010_006235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CG010_006250	COG3243	poly(R)-hydroxyalkanoic acid synthase
CG010_006255	COG1489	DNA binding
CG010_006260	COG0024	Methionine aminopeptidase
CG010_006265	COG2003	Belongs to the UPF0758 family
CG010_006280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CG010_006305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CG010_006310	COG0546	phosphoglycolate phosphatase activity
CG010_006320	COG0114	fumarate hydratase activity
CG010_006330	COG0504	CTP synthase activity
CG010_006340	COG0149	triose-phosphate isomerase activity
CG010_006350	COG0187	DNA topoisomerase II activity
CG010_006360	COG0740	serine-type endopeptidase activity
CG010_006370	COG0640	Transcriptional regulator
CG010_006375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG010_006395	COG3264	Mechanosensitive ion channel
CG010_006395	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CG010_006465	COG1127	ABC transporter
CG010_006470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CG010_006475	COG4948	Mandelate Racemase Muconate Lactonizing
CG010_006485	COG0281	malic enzyme
CG010_006485	COG0280	phosphate acetyltransferase
CG010_006495	COG0778	Nitroreductase
CG010_006500	COG0823	Involved in the tonB-independent uptake of proteins
CG010_006515	COG1368	sulfuric ester hydrolase activity
CG010_006540	COG0544	peptidyl-prolyl cis-trans isomerase activity
CG010_006565	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CG010_006585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CG010_006600	COG0318	PFAM AMP-dependent synthetase and ligase
CG010_006610	COG0512	Glutamine amidotransferase of anthranilate synthase
CG010_006610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG010_006615	COG0343	queuine tRNA-ribosyltransferase activity
CG010_006620	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CG010_006630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG010_006635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CG010_006640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CG010_006665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CG010_006670	COG0134	indole-3-glycerol-phosphate synthase activity
CG010_006675	COG0315	cyclic pyranopterin monophosphate synthase activity
CG010_006680	COG0303	'Molybdopterin
CG010_006685	COG3706	GGDEF domain
CG010_006695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CG010_006695	COG0475	glutathione-regulated potassium exporter activity
CG010_006705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CG010_006715	COG2814	Major facilitator Superfamily
CG010_006720	COG0746	molybdenum cofactor guanylyltransferase activity
CG010_006725	COG1763	Mo-molybdopterin cofactor biosynthetic process
CG010_006730	COG0739	heme binding
CG010_006735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CG010_006740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CG010_006745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG010_006750	COG0805	protein transport
CG010_006755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG010_006760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CG010_006765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG010_006770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CG010_006775	COG1472	Belongs to the glycosyl hydrolase 3 family
CG010_006785	COG0018	arginyl-trna synthetase
CG010_006790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CG010_006820	COG0525	valine-tRNA ligase activity
CG010_006830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CG010_006960	COG1525	nuclease
CG010_007035	COG3567	Phage-associated protein, HI1409 family
CG010_007080	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CG010_007275	COG0655	NAD(P)H dehydrogenase (quinone) activity
CG010_007280	COG1546	Belongs to the CinA family
CG010_007280	COG1058	Belongs to the CinA family
CG010_007285	COG0589	response to stress
CG010_007290	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CG010_007300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CG010_007310	COG0640	Transcriptional regulator
CG010_007315	COG1914	H( )-stimulated, divalent metal cation uptake system
CG010_007325	COG1132	(ABC) transporter
CG010_007330	COG0628	permease
CG010_007365	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CG010_007375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CG010_007385	COG0302	gtp cyclohydrolase
CG010_007390	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CG010_007395	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG010_007405	COG0516	GMP reductase activity
CG010_007405	COG0517	IMP dehydrogenase activity
CG010_007440	COG1760	l-serine dehydratase
CG010_007475	COG0583	DNA-binding transcription factor activity
CG010_007490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CG010_007490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CG010_007500	COG0347	Belongs to the P(II) protein family
CG010_007505	COG0174	glutamine synthetase
CG010_007535	COG0697	spore germination
CG010_007545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CG010_007555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CG010_007585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CG010_007590	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CG010_007595	COG2186	Transcriptional regulator
CG010_007615	COG1129	ABC transporter
CG010_007620	COG1183	phosphatidylcholine synthase activity
CG010_007625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG010_007630	COG0679	Auxin Efflux Carrier
CG010_007635	COG0785	Cytochrome C biogenesis protein
CG010_007660	COG1278	Cold shock
CG010_007720	COG1136	(ABC) transporter
CG010_007720	COG0577	efflux transmembrane transporter activity
CG010_007725	COG0577	efflux transmembrane transporter activity
CG010_007725	COG1136	(ABC) transporter
CG010_007750	COG2151	metal-sulfur cluster biosynthetic enzyme
CG010_007755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CG010_007760	COG0719	Fe-S assembly protein
CG010_007765	COG0396	ATPase activity
CG010_007770	COG0719	Fe-S assembly protein
CG010_007775	COG1104	cysteine desulfurase activity
CG010_007780	COG2945	thiolester hydrolase activity
CG010_007790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CG010_007795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG010_007805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CG010_007810	COG2833	Protein of unknown function (DUF455)
CG010_007815	COG0739	heme binding
CG010_007820	COG0513	Belongs to the DEAD box helicase family
CG010_007845	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG010_007855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG010_007860	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG010_007865	COG0047	phosphoribosylformylglycinamidine synthase activity
CG010_007885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG010_007890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CG010_007910	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CG010_007915	COG2814	Major facilitator Superfamily
CG010_007920	COG0483	inositol monophosphate 1-phosphatase activity
CG010_007925	COG0483	inositol monophosphate 1-phosphatase activity
CG010_007930	COG0037	tRNA processing
CG010_007935	COG2066	Belongs to the glutaminase family
CG010_007940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CG010_007945	COG0861	Integral membrane protein TerC family
CG010_007960	COG1280	lysine exporter protein (LysE YggA)
CG010_007975	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CG010_007980	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CG010_007990	COG0538	isocitrate dehydrogenase activity
CG010_008000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CG010_008005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CG010_008010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_008015	COG2313	pseudouridylate synthase activity
CG010_008030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_008035	COG4215	(ABC) transporter
CG010_008045	COG5425	PFAM Usg family protein
CG010_008055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG010_008060	COG1522	sequence-specific DNA binding
CG010_008065	COG1573	uracil-dna glycosylase
CG010_008075	COG2202	Pas domain
CG010_008075	COG2205	protein histidine kinase activity
CG010_008080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CG010_008085	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CG010_008090	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CG010_008105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CG010_008110	COG0842	Transport permease protein
CG010_008115	COG1131	(ABC) transporter
CG010_008135	COG0840	transmembrane signaling receptor activity
CG010_008145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CG010_008150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CG010_008170	COG0129	dihydroxy-acid dehydratase activity
CG010_008175	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CG010_008180	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CG010_008190	COG3739	integral membrane protein
CG010_008195	COG0203	ribosomal protein L17
CG010_008200	COG0202	RNA polymerase activity
CG010_008205	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CG010_008210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CG010_008215	COG0563	adenylate kinase activity
CG010_008220	COG0201	protein transport
CG010_008225	COG0200	Binds to the 23S rRNA
CG010_008230	COG1841	ribosomal large subunit assembly
CG010_008235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CG010_008240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CG010_008245	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CG010_008250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CG010_008255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CG010_008260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CG010_008265	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CG010_008270	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CG010_008275	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CG010_008280	COG0255	Belongs to the universal ribosomal protein uL29 family
CG010_008285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CG010_008290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CG010_008295	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CG010_008300	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CG010_008305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CG010_008310	COG0089	rRNA binding
CG010_008315	COG0088	Forms part of the polypeptide exit tunnel
CG010_008320	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CG010_008325	COG0051	transcription antitermination factor activity, RNA binding
CG010_008330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG010_008335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CG010_008340	COG0049	tRNA binding
CG010_008345	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CG010_008365	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CG010_008370	COG0085	RNA polymerase activity
CG010_008375	COG0222	ribosome binding
CG010_008380	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CG010_008385	COG0081	regulation of translation
CG010_008390	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CG010_008410	COG1086	Polysaccharide biosynthesis protein
CG010_008415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CG010_008420	COG0861	Integral membrane protein TerC family
CG010_008430	COG3895	Periplasmic Protein
CG010_008455	COG1132	(ABC) transporter
CG010_008460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG010_008480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CG010_008515	COG2205	protein histidine kinase activity
CG010_008515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_008515	COG0784	Response regulator, receiver
CG010_008515	COG2198	Histidine kinase
CG010_008520	COG0784	Response regulator, receiver
CG010_008525	COG2202	Pas domain
CG010_008525	COG3920	Histidine kinase
CG010_008530	COG0784	Response regulator, receiver
CG010_008535	COG4251	negative regulation of phosphorylation
CG010_008550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CG010_008555	COG1607	acyl-coa hydrolase
CG010_008575	COG2910	NAD(P)H-binding
CG010_008580	COG1733	regulation of RNA biosynthetic process
CG010_008595	COG0556	nucleotide-excision repair
CG010_008605	COG2382	esterase
CG010_008625	COG0484	heat shock protein binding
CG010_008650	COG3706	GGDEF domain
CG010_008670	COG1840	ABC-type Fe3 transport system, periplasmic component
CG010_008680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG010_008685	COG4154	Belongs to the RbsD FucU family
CG010_008695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CG010_008705	COG2207	Transcriptional regulator
CG010_008710	COG1064	alcohol dehydrogenase
CG010_008715	COG1252	NADH dehydrogenase
CG010_008720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CG010_008725	COG2197	response regulator
CG010_008730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CG010_008765	COG0656	L-ascorbic acid biosynthetic process
CG010_008780	COG0440	acetolactate synthase activity
CG010_008785	COG0028	Belongs to the TPP enzyme family
CG010_008795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CG010_008800	COG3830	Belongs to the UPF0237 family
CG010_008800	COG0560	Phosphoserine phosphatase
CG010_008820	COG0330	HflC and HflK could
CG010_008825	COG0330	HflC and HflK could
CG010_008835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CG010_008870	COG0277	FAD linked oxidase domain protein
CG010_008875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG010_008915	COG1335	isochorismatase
CG010_008950	COG2264	protein methyltransferase activity
CG010_008955	COG1999	signal sequence binding
CG010_008965	COG0835	chemotaxis
CG010_008975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG010_008980	COG0583	DNA-binding transcription factor activity
CG010_008990	COG1247	-acetyltransferase
CG010_009000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CG010_009005	COG0497	DNA recombination
CG010_009010	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CG010_009020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG010_009025	COG0849	cell division
CG010_009030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CG010_009035	COG1181	Belongs to the D-alanine--D-alanine ligase family
CG010_009040	COG0477	Major facilitator Superfamily
CG010_009045	COG5001	Diguanylate cyclase
CG010_009050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CG010_009055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CG010_009060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG010_009070	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CG010_009075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CG010_009085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CG010_009100	COG0275	rRNA processing
CG010_009105	COG2001	Belongs to the MraZ family
CG010_009130	COG3023	N-Acetylmuramoyl-L-alanine amidase
CG010_009135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CG010_009160	COG4106	trans-aconitate 2-methyltransferase activity
CG010_009190	COG2267	carboxylic ester hydrolase activity
CG010_009195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CG010_009210	COG0251	oxidation-reduction process
CG010_009225	COG1376	ErfK ybiS ycfS ynhG family protein
CG010_009230	COG2814	Major facilitator Superfamily
CG010_009265	COG1012	belongs to the aldehyde dehydrogenase family
CG010_009270	COG0174	glutamine synthetase
CG010_009275	COG0531	amino acid
CG010_009285	COG1737	Transcriptional regulator
CG010_009295	COG2182	Extracellular solute-binding protein
CG010_009310	COG3842	ATPase activity
CG010_009370	COG2968	Membrane
CG010_009380	COG0432	Pfam Uncharacterised protein family UPF0047
CG010_009395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG010_009400	COG0358	DNA primase activity
CG010_009420	COG0505	Belongs to the CarA family
CG010_009425	COG0534	Mate efflux family protein
CG010_009440	COG2321	neutral zinc metallopeptidase
CG010_009455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CG010_009465	COG3706	GGDEF domain
CG010_009480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG010_009490	COG1522	sequence-specific DNA binding
CG010_009495	COG0492	ferredoxin-NADP+ reductase activity
CG010_009500	COG0583	DNA-binding transcription factor activity
CG010_009510	COG1902	pentaerythritol trinitrate reductase activity
CG010_009540	COG0387	Pfam Sodium calcium exchanger
CG010_009550	COG2199	diguanylate cyclase activity
CG010_009550	COG2200	EAL domain
CG010_009565	COG1278	Cold shock
CG010_009570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG010_009585	COG1846	Transcriptional regulator
CG010_009590	COG0745	RESPONSE REGULATOR receiver
CG010_009595	COG2205	protein histidine kinase activity
CG010_009600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG010_009625	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CG010_009650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CG010_009660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CG010_009675	COG0840	transmembrane signaling receptor activity
CG010_009680	COG1012	belongs to the aldehyde dehydrogenase family
CG010_009690	COG3300	MHYT domain
CG010_009690	COG5001	Diguanylate cyclase
CG010_009695	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CG010_009700	COG5001	Diguanylate cyclase
CG010_009710	COG0193	aminoacyl-tRNA hydrolase activity
CG010_009720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CG010_009745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CG010_009755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CG010_009755	COG2857	Cytochrome c1
CG010_009775	COG1132	(ABC) transporter
CG010_009785	COG1132	(ABC) transporter
CG010_009795	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CG010_009810	COG0408	coproporphyrinogen oxidase activity
CG010_009825	COG0617	tRNA 3'-terminal CCA addition
CG010_009840	COG0714	Associated with various cellular activities
CG010_009860	COG0454	-acetyltransferase
CG010_009875	COG0477	Major facilitator Superfamily
CG010_009885	COG0435	Glutathione S-transferase
CG010_009890	COG0494	nUDIX hydrolase
CG010_009905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG010_009910	COG3135	benzoate transporter
CG010_009935	COG0740	serine-type endopeptidase activity
CG010_009950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CG010_009955	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CG010_009985	COG4175	Glycine betaine
CG010_010000	COG1435	thymidine kinase activity
CG010_010025	COG4771	TonB-dependent receptor
CG010_010025	COG1629	transport
CG010_010035	COG0512	Glutamine amidotransferase of anthranilate synthase
CG010_010035	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CG010_010050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CG010_010060	COG0366	Alpha amylase catalytic
CG010_010065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_010085	COG1160	GTP binding
CG010_010105	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CG010_010115	COG0024	Methionine aminopeptidase
CG010_010130	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_010150	COG0583	DNA-binding transcription factor activity
CG010_010165	COG0402	S-adenosylhomocysteine deaminase activity
CG010_010175	COG1304	FMN binding
CG010_010185	COG1309	transcriptional regulator
CG010_010190	COG1686	Belongs to the peptidase S11 family
CG010_010200	COG2351	hydroxyisourate hydrolase activity
CG010_010205	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CG010_010230	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CG010_010240	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CG010_010240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_010250	COG0513	Belongs to the DEAD box helicase family
CG010_010265	COG2259	Doxx family
CG010_010270	COG1376	ErfK ybiS ycfS ynhG family protein
CG010_010280	COG2308	Evidence 4 Homologs of previously reported genes of
CG010_010290	COG1305	Transglutaminase-like
CG010_010315	COG4214	carbohydrate transport
CG010_010325	COG4213	ABC transporter substrate-binding protein
CG010_010385	COG2948	multi-organism process
CG010_010395	COG3701	Conjugal transfer protein
CG010_010400	COG3846	protein secretion by the type IV secretion system
CG010_010415	COG3451	type IV secretory pathway VirB4
CG010_010430	COG4962	Type ii secretion system protein e
CG010_010455	COG0583	DNA-binding transcription factor activity
CG010_010465	COG1566	PFAM secretion protein HlyD family protein
CG010_010480	COG2207	Transcriptional regulator
CG010_010485	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_010495	COG0583	DNA-binding transcription factor activity
CG010_010505	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CG010_010520	COG0583	DNA-binding transcription factor activity
CG010_010530	COG0741	lytic transglycosylase activity
CG010_010555	COG1192	Involved in chromosome partitioning
CG010_010595	COG2814	Major facilitator Superfamily
CG010_010605	COG5489	Protein of unknown function (DUF736)
CG010_010620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG010_010650	COG1204	response to ionizing radiation
CG010_010665	COG0514	ATP-dependent DNA helicase (RecQ)
CG010_010715	COG0583	DNA-binding transcription factor activity
CG010_010720	COG1902	pentaerythritol trinitrate reductase activity
CG010_010725	COG0583	DNA-binding transcription factor activity
CG010_010740	COG1335	isochorismatase
CG010_010745	COG0583	DNA-binding transcription factor activity
CG010_010750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG010_010760	COG4584	PFAM Integrase catalytic
CG010_010775	COG0840	transmembrane signaling receptor activity
CG010_010790	COG0646	methionine synthase
CG010_010790	COG1410	methionine synthase
CG010_010800	COG4215	(ABC) transporter
CG010_010805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_010840	COG1215	transferase activity, transferring glycosyl groups
CG010_010875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG010_010890	COG2346	COG2346, Truncated hemoglobins
CG010_010910	COG1309	transcriptional regulator
CG010_010925	COG0494	nUDIX hydrolase
CG010_010940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_010945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_010980	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CG010_010985	COG0830	nickel cation binding
CG010_010990	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CG010_011005	COG0804	urea catabolic process
CG010_011010	COG1442	glycosyl transferase family 8
CG010_011015	COG3755	Protein conserved in bacteria
CG010_011025	COG0832	Belongs to the urease beta subunit family
CG010_011030	COG3813	Protein conserved in bacteria
CG010_011035	COG0831	urea catabolic process
CG010_011040	COG0829	nickel cation binding
CG010_011070	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG010_011090	COG0174	glutamine synthetase
CG010_011095	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_011100	COG0784	Response regulator, receiver
CG010_011100	COG2198	Histidine kinase
CG010_011100	COG5002	protein histidine kinase activity
CG010_011115	COG0726	polysaccharide deacetylase
CG010_011135	COG0411	ABC transporter
CG010_011150	COG1218	3'(2'),5'-bisphosphate nucleotidase
CG010_011235	COG0564	pseudouridine synthase activity
CG010_011250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CG010_011260	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CG010_011290	COG0346	lactoylglutathione lyase activity
CG010_011300	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CG010_011310	COG2832	Protein of unknown function (DUF454)
CG010_011315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CG010_011320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_011325	COG4558	Periplasmic binding protein
CG010_011335	COG3721	Heme iron utilization protein
CG010_011350	COG3655	Transcriptional regulator
CG010_011380	COG2205	protein histidine kinase activity
CG010_011420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_011425	COG4605	iron ion homeostasis
CG010_011430	COG4604	ABC transporter, ATP-binding protein
CG010_011435	COG0783	Belongs to the Dps family
CG010_011450	COG0840	transmembrane signaling receptor activity
CG010_011450	COG2972	Histidine kinase
CG010_011455	COG0656	L-ascorbic acid biosynthetic process
CG010_011460	COG2814	Major facilitator Superfamily
CG010_011470	COG0583	DNA-binding transcription factor activity
CG010_011480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_011500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG010_011505	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CG010_011510	COG0288	reversible hydration of carbon dioxide
CG010_011520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CG010_011540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CG010_011545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG010_011550	COG0778	Nitroreductase
CG010_011555	COG2267	carboxylic ester hydrolase activity
CG010_011560	COG0251	oxidation-reduction process
CG010_011565	COG1335	isochorismatase
CG010_011570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_011580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_011595	COG1175	transmembrane transport
CG010_011600	COG0395	ABC-type sugar transport system, permease component
CG010_011605	COG3842	ATPase activity
CG010_011610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_011620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG010_011635	COG4608	Belongs to the ABC transporter superfamily
CG010_011640	COG0444	Belongs to the ABC transporter superfamily
CG010_011650	COG0601	transmembrane transport
CG010_011705	COG2159	amidohydrolase
CG010_011710	COG1960	acyl-CoA dehydrogenase activity
CG010_011740	COG0745	RESPONSE REGULATOR receiver
CG010_011750	COG1902	pentaerythritol trinitrate reductase activity
CG010_011750	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG010_011755	COG3842	ATPase activity
CG010_011765	COG1840	ABC-type Fe3 transport system, periplasmic component
CG010_011770	COG1840	ABC-type Fe3 transport system, periplasmic component
CG010_011775	COG0745	RESPONSE REGULATOR receiver
CG010_011785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG010_011790	COG0583	DNA-binding transcription factor activity
CG010_011795	COG1278	Cold shock
CG010_011845	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CG010_011850	COG1309	transcriptional regulator
CG010_011855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_011860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG010_011870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CG010_011875	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CG010_011895	COG0583	DNA-binding transcription factor activity
CG010_011900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_011910	COG0725	ABC transporter, periplasmic molybdate-binding protein
CG010_011915	COG4149	molybdate abc transporter
CG010_011920	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CG010_011935	COG2022	thiamine diphosphate biosynthetic process
CG010_011950	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CG010_011955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG010_011965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CG010_011985	COG1132	(ABC) transporter
CG010_011990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CG010_012035	COG4166	transmembrane transport
CG010_012040	COG0601	transmembrane transport
CG010_012045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_012060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CG010_012065	COG3142	Participates in the control of copper homeostasis
CG010_012070	COG2814	Major facilitator Superfamily
CG010_012085	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_012090	COG1737	Transcriptional regulator
CG010_012100	COG3842	ATPase activity
CG010_012110	COG0395	ABC-type sugar transport system, permease component
CG010_012140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CG010_012145	COG1940	carbohydrate kinase activity
CG010_012155	COG0671	phosphoesterase, PA-phosphatase related
CG010_012160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CG010_012165	COG0156	8-amino-7-oxononanoate synthase activity
CG010_012175	COG0729	surface antigen
CG010_012185	COG0835	chemotaxis
CG010_012195	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CG010_012200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CG010_012205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CG010_012210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CG010_012215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CG010_012220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CG010_012235	COG4974	Belongs to the 'phage' integrase family
CG010_012260	COG1280	lysine exporter protein (LysE YggA)
CG010_012270	COG0508	dehydrogenase complex catalyzes the overall conversion of
CG010_012275	COG0567	Dehydrogenase, E1 component
CG010_012280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CG010_012285	COG0045	succinate-CoA ligase (ADP-forming) activity
CG010_012290	COG0039	L-malate dehydrogenase activity
CG010_012295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CG010_012345	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CG010_012350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CG010_012355	COG0181	hydroxymethylbilane synthase activity
CG010_012390	COG1872	DUF167
CG010_012395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CG010_012410	COG0339	signal peptide processing
CG010_012415	COG1846	Transcriptional regulator
CG010_012425	COG0137	argininosuccinate synthase activity
CG010_012435	COG1280	lysine exporter protein (LysE YggA)
CG010_012440	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CG010_012445	COG4120	Belongs to the binding-protein-dependent transport system permease family
CG010_012455	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CG010_012470	COG2154	pterin-4-alpha-carbinolamine dehydratase
CG010_012475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CG010_012480	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CG010_012490	COG4181	ATPase activity
CG010_012500	COG0670	Belongs to the BI1 family
CG010_012515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CG010_012520	COG4133	protoheme IX ABC transporter activity
CG010_012530	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG010_012535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CG010_012550	COG3706	GGDEF domain
CG010_012560	COG2917	probably involved in intracellular septation
CG010_012565	COG0552	protein localization to endoplasmic reticulum
CG010_012570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CG010_012575	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CG010_012590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CG010_012595	COG1605	Chorismate mutase
CG010_012595	COG0287	Prephenate dehydrogenase
CG010_012600	COG0228	four-way junction DNA binding
CG010_012605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CG010_012610	COG0336	Belongs to the RNA methyltransferase TrmD family
CG010_012620	COG0335	large ribosomal subunit rRNA binding
CG010_012625	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CG010_012630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_012650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CG010_012665	COG4783	chaperone-mediated protein folding
CG010_012675	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CG010_012705	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CG010_012715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CG010_012720	COG0142	geranyltranstransferase activity
CG010_012725	COG2885	chlorophyll binding
CG010_012730	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CG010_012735	COG2223	nitrite transmembrane transporter activity
CG010_012745	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CG010_012750	COG2197	response regulator
CG010_012755	COG1132	(ABC) transporter
CG010_012765	COG3459	Glycosyltransferase 36 associated
CG010_012770	COG1473	amidohydrolase
CG010_012780	COG0579	oxidoreductase
CG010_012790	COG0129	dihydroxy-acid dehydratase activity
CG010_012795	COG2084	Dehydrogenase
CG010_012800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG010_012805	COG0277	FAD linked oxidase domain protein
CG010_012810	COG2186	Transcriptional regulator
CG010_012820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG010_012825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG010_012830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG010_012835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG010_012845	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CG010_012850	COG0495	leucyl-tRNA aminoacylation
CG010_012870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CG010_012885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG010_012890	COG1946	Acyl-CoA thioesterase
CG010_012895	COG0347	Belongs to the P(II) protein family
CG010_012900	COG0004	ammonium transporteR
CG010_012905	COG1674	ftsk spoiiie
CG010_012910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CG010_012925	COG0745	RESPONSE REGULATOR receiver
CG010_012935	COG1329	Transcriptional regulator
CG010_012945	COG2270	Major facilitator Superfamily
CG010_012960	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_012975	COG0494	nUDIX hydrolase
CG010_012980	COG2861	carbohydrate metabolic process
CG010_012985	COG0793	Belongs to the peptidase S41A family
CG010_012995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CG010_013000	COG0799	negative regulation of ribosome biogenesis
CG010_013005	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CG010_013010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CG010_013015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CG010_013020	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CG010_013035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CG010_013040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CG010_013065	COG0066	3-isopropylmalate dehydratase activity
CG010_013070	COG0473	3-isopropylmalate dehydrogenase activity
CG010_013075	COG1858	cytochrome C peroxidase
CG010_013080	COG1797	cobyrinic acid a,c-diamide synthase activity
CG010_013090	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CG010_013155	COG1492	cobalamin metabolic process
CG010_013170	COG4948	Mandelate Racemase Muconate Lactonizing
CG010_013175	COG3254	rhamnose metabolic process
CG010_013180	COG0246	Mannitol dehydrogenase
CG010_013185	COG1063	alcohol dehydrogenase
CG010_013210	COG1129	ABC transporter
CG010_013215	COG2186	Transcriptional regulator
CG010_013220	COG2721	sulfolactate sulfo-lyase activity
CG010_013225	COG0138	bifunctional purine biosynthesis protein purh
CG010_013235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CG010_013235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CG010_013240	COG0501	Belongs to the peptidase M48B family
CG010_013250	COG1475	DNA binding
CG010_013255	COG1192	Involved in chromosome partitioning
CG010_013260	COG0357	Ribosomal RNA small subunit methyltransferase G
CG010_013265	COG0445	tRNA wobble uridine modification
CG010_013270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CG010_013275	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CG010_013285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CG010_013290	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CG010_013295	COG0424	maF-like protein
CG010_013300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG010_013305	COG0237	dephospho-CoA kinase activity
CG010_013310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CG010_013315	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CG010_013320	COG3030	protein affecting phage T7 exclusion by the F plasmid
CG010_013330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CG010_013345	COG0187	DNA topoisomerase II activity
CG010_013355	COG0179	Fumarylacetoacetate (FAA) hydrolase
CG010_013370	COG0135	phosphoribosylanthranilate isomerase activity
CG010_013375	COG0133	tryptophan synthase activity
CG010_013380	COG0159	tryptophan synthase activity
CG010_013385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CG010_013400	COG1074	ATP-dependent DNA helicase activity
CG010_013410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CG010_013415	COG0802	atpase or kinase
CG010_013420	COG2205	protein histidine kinase activity
CG010_013430	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CG010_013435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG010_013440	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CG010_013440	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CG010_013445	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CG010_013450	COG0642	Histidine kinase
CG010_013455	COG0745	RESPONSE REGULATOR receiver
CG010_013460	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CG010_013470	COG1652	LysM domain
CG010_013475	COG1072	(Pantothenic acid kinase))
CG010_013480	COG0140	phosphoribosyl-ATP diphosphatase activity
CG010_013485	COG0107	imidazoleglycerol-phosphate synthase activity
CG010_013490	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CG010_013495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CG010_013505	COG0131	Imidazoleglycerol-phosphate dehydratase
CG010_013510	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CG010_013515	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CG010_013525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CG010_013540	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CG010_013550	COG1643	Atp-dependent helicase
CG010_013605	COG1940	carbohydrate kinase activity
CG010_013625	COG1072	(Pantothenic acid kinase))
CG010_013635	COG1780	Probably involved in ribonucleotide reductase function
CG010_013655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CG010_013685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_013695	COG2813	Specifically methylates the guanine in position
CG010_013700	COG1185	polyribonucleotide nucleotidyltransferase activity
CG010_013705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CG010_013710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CG010_013715	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CG010_013720	COG3064	Membrane
CG010_013720	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CG010_013735	COG0779	Required for maturation of 30S ribosomal subunits
CG010_013740	COG2814	Major facilitator Superfamily
CG010_013750	COG2951	lytic endotransglycosylase activity
CG010_013755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CG010_013765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CG010_013770	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CG010_013785	COG2816	NAD+ diphosphatase activity
CG010_013790	COG0077	Prephenate dehydratase
CG010_013790	COG1605	Chorismate mutase
CG010_013795	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CG010_013800	COG3474	cytochrome
CG010_013810	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CG010_013815	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CG010_013825	COG1278	Cold shock
CG010_013830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG010_013840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG010_013840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CG010_013845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CG010_013880	COG2900	Belongs to the SlyX family
CG010_013890	COG0484	heat shock protein binding
CG010_013895	COG0443	Heat shock 70 kDa protein
CG010_013910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CG010_013935	COG0295	cytidine deaminase activity
CG010_013940	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CG010_013945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CG010_013950	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CG010_013960	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CG010_013965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CG010_013970	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CG010_013980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CG010_013985	COG1845	cytochrome c oxidase, subunit III
CG010_013990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG010_013995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG010_014000	COG0477	Major facilitator Superfamily
CG010_014010	COG0069	glutamate synthase activity
CG010_014010	COG0067	glutamate synthase
CG010_014010	COG0070	glutamate synthase
CG010_014015	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CG010_014030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CG010_014040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CG010_014075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_014095	COG0848	biopolymer transport protein
CG010_014105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG010_014120	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CG010_014125	COG3454	Phosphonate metabolism
CG010_014130	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CG010_014135	COG3639	organic phosphonate transmembrane transporter activity
CG010_014140	COG3639	organic phosphonate transmembrane transporter activity
CG010_014150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CG010_014160	COG4778	phosphonate C-P lyase system protein PhnL
CG010_014165	COG4107	phosphonate C-P lyase system protein PhnK
CG010_014170	COG3627	carbon phosphorus lyase activity
CG010_014175	COG3626	phosphonate metabolism
CG010_014180	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CG010_014185	COG3624	Phosphonate C-P lyase system protein PhnG
CG010_014190	COG2188	Transcriptional regulator
CG010_014195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CG010_014200	COG0837	glucose binding
CG010_014205	COG1803	Methylglyoxal synthase
CG010_014210	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CG010_014215	COG4166	transmembrane transport
CG010_014220	COG4174	ABC transporter (Permease)
CG010_014225	COG4239	(ABC) transporter, permease
CG010_014230	COG4172	Belongs to the ABC transporter superfamily
CG010_014235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_014240	COG0174	glutamine synthetase
CG010_014245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_014250	COG3265	gluconokinase activity
CG010_014255	COG1174	glycine betaine transport
CG010_014260	COG1125	glycine betaine transport
CG010_014265	COG1174	glycine betaine transport
CG010_014270	COG1732	Glycine betaine
CG010_014280	COG1959	2 iron, 2 sulfur cluster binding
CG010_014285	COG1840	ABC-type Fe3 transport system, periplasmic component
CG010_014295	COG4269	membrane
CG010_014310	COG0697	spore germination
CG010_014325	COG0791	NLP P60 protein
CG010_014335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CG010_014340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CG010_014375	COG4964	Belongs to the GSP D family
CG010_014425	COG3422	double-strand break repair
CG010_014430	COG3757	hydrolase, family 25
CG010_014435	COG0697	spore germination
CG010_014440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG010_014455	COG0492	ferredoxin-NADP+ reductase activity
CG010_014470	COG0481	GTPase activity
CG010_014475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG010_014490	COG1396	sequence-specific DNA binding
CG010_014505	COG2169	Transcriptional regulator
CG010_014505	COG1917	Cupin 2, conserved barrel domain protein
CG010_014510	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG010_014535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CG010_014540	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CG010_014545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CG010_014555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CG010_014560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CG010_014560	COG0072	phenylalanine-tRNA ligase activity
CG010_014565	COG0667	Aldo Keto reductase
CG010_014585	COG4977	sequence-specific DNA binding
CG010_014610	COG1570	exodeoxyribonuclease VII activity
CG010_014615	COG4948	Mandelate Racemase Muconate Lactonizing
CG010_014625	COG1846	Transcriptional regulator
CG010_014635	COG2309	aminopeptidase activity
CG010_014645	COG1393	Belongs to the ArsC family
CG010_014665	COG1309	transcriptional regulator
CG010_014675	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CG010_014675	COG0519	Catalyzes the synthesis of GMP from XMP
CG010_014690	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CG010_014720	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CG010_014730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CG010_014740	COG1968	undecaprenyl-diphosphatase activity
CG010_014765	COG0284	orotidine-5'-phosphate decarboxylase activity
CG010_014775	COG3963	phosphatidate phosphatase activity
CG010_014780	COG0592	DNA-directed DNA polymerase activity
CG010_014785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CG010_014790	COG0792	nuclease activity
CG010_014805	COG1175	transmembrane transport
CG010_014810	COG0395	ABC-type sugar transport system, permease component
CG010_014815	COG3842	ATPase activity
CG010_014825	COG0189	ligase activity
CG010_014835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG010_014840	COG1280	lysine exporter protein (LysE YggA)
CG010_014845	COG0756	dUTP diphosphatase activity
CG010_014850	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CG010_014855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CG010_014870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CG010_014875	COG2226	methyltransferase
CG010_014880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CG010_014885	COG1024	Enoyl-CoA hydratase
CG010_014890	COG0268	Binds directly to 16S ribosomal RNA
CG010_014895	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CG010_014930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CG010_014965	COG1278	Cold shock
CG010_015000	COG0411	ABC transporter
CG010_015005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG010_015010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG010_015015	COG1454	alcohol dehydrogenase
CG010_015020	COG0747	negative chemotaxis
CG010_015025	COG0601	transmembrane transport
CG010_015035	COG4608	Belongs to the ABC transporter superfamily
CG010_015040	COG1349	DNA-binding transcription factor activity
CG010_015045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG010_015070	COG4302	ethanolamine ammonia-lyase activity
CG010_015075	COG0025	NhaP-type Na H and K H
CG010_015080	COG4106	trans-aconitate 2-methyltransferase activity
CG010_015090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_015095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_015100	COG0601	transmembrane transport
CG010_015125	COG4172	Belongs to the ABC transporter superfamily
CG010_015135	COG3706	GGDEF domain
CG010_015165	COG0745	RESPONSE REGULATOR receiver
CG010_015170	COG2205	protein histidine kinase activity
CG010_015175	COG1764	response to oxidative stress
CG010_015185	COG0596	Alpha beta hydrolase
CG010_015200	COG0783	Belongs to the Dps family
CG010_015205	COG0243	molybdopterin cofactor binding
CG010_015215	COG4566	intracellular signal transduction
CG010_015220	COG4566	intracellular signal transduction
CG010_015250	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG010_015260	COG1414	Transcriptional regulator
CG010_015275	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_015295	COG1522	sequence-specific DNA binding
CG010_015320	COG0628	permease
CG010_015330	COG2235	arginine
CG010_015365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CG010_015375	COG0702	epimerase
CG010_015380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG010_015385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_015390	COG0745	RESPONSE REGULATOR receiver
CG010_015395	COG5002	protein histidine kinase activity
CG010_015410	COG2233	PERMEase
CG010_015465	COG0395	ABC-type sugar transport system, permease component
CG010_015470	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_015480	COG3842	ATPase activity
CG010_015520	COG1653	transport
CG010_015530	COG0395	ABC-type sugar transport system, permease component
CG010_015535	COG3842	ATPase activity
CG010_015550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG010_015555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_015560	COG1116	anion transmembrane transporter activity
CG010_015565	COG0395	ABC-type sugar transport system, permease component
CG010_015570	COG1175	transmembrane transport
CG010_015600	COG1609	Transcriptional regulator
CG010_015615	COG1082	Xylose isomerase domain protein TIM barrel
CG010_015620	COG3842	ATPase activity
CG010_015625	COG0395	ABC-type sugar transport system, permease component
CG010_015630	COG1175	transmembrane transport
CG010_015635	COG1653	transport
CG010_015640	COG1309	transcriptional regulator
CG010_015645	COG0673	inositol 2-dehydrogenase activity
CG010_015660	COG0673	inositol 2-dehydrogenase activity
CG010_015665	COG1278	Cold shock
CG010_015675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG010_015695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CG010_015700	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CG010_015720	COG0395	ABC-type sugar transport system, permease component
CG010_015725	COG1175	transmembrane transport
CG010_015735	COG3618	amidohydrolase
CG010_015740	COG4948	Mandelate Racemase Muconate Lactonizing
CG010_015745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_015750	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_015755	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CG010_015760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG010_015765	COG2186	Transcriptional regulator
CG010_015780	COG0667	Aldo Keto reductase
CG010_015815	COG4977	sequence-specific DNA binding
CG010_015820	COG2223	nitrite transmembrane transporter activity
CG010_015825	COG1609	Transcriptional regulator
CG010_015830	COG1063	alcohol dehydrogenase
CG010_015835	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_015850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_015855	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CG010_015860	COG1175	transmembrane transport
CG010_015865	COG0395	ABC-type sugar transport system, permease component
CG010_015880	COG0395	ABC-type sugar transport system, permease component
CG010_015895	COG0626	cystathionine gamma-synthase activity
CG010_015910	COG0454	-acetyltransferase
CG010_015915	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG010_015925	COG1121	(ABC) transporter
CG010_015930	COG0523	cobalamin synthesis protein
CG010_015945	COG0523	cobalamin synthesis protein
CG010_015950	COG1653	transport
CG010_015955	COG1175	transmembrane transport
CG010_015960	COG0395	ABC-type sugar transport system, permease component
CG010_015965	COG3842	ATPase activity
CG010_015975	COG3047	cAMP biosynthetic process
CG010_016000	COG0583	DNA-binding transcription factor activity
CG010_016005	COG1879	ABC-type sugar transport system periplasmic component
CG010_016010	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_016015	COG1129	ABC transporter
CG010_016025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CG010_016030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_016040	COG3257	ureidoglycine aminohydrolase activity
CG010_016050	COG5001	Diguanylate cyclase
CG010_016055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG010_016065	COG0747	negative chemotaxis
CG010_016070	COG0601	transmembrane transport
CG010_016075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_016085	COG4608	Belongs to the ABC transporter superfamily
CG010_016090	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CG010_016105	COG0346	lactoylglutathione lyase activity
CG010_016115	COG0129	dihydroxy-acid dehydratase activity
CG010_016125	COG1879	ABC-type sugar transport system periplasmic component
CG010_016130	COG1129	ABC transporter
CG010_016135	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_016140	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_016145	COG2186	Transcriptional regulator
CG010_016160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG010_016165	COG0587	DNA-directed DNA polymerase activity
CG010_016170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG010_016195	COG0673	inositol 2-dehydrogenase activity
CG010_016205	COG3842	ATPase activity
CG010_016210	COG0395	ABC-type sugar transport system, permease component
CG010_016215	COG1175	transmembrane transport
CG010_016220	COG1653	transport
CG010_016230	COG0673	inositol 2-dehydrogenase activity
CG010_016245	COG5001	Diguanylate cyclase
CG010_016255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_016260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CG010_016265	COG2894	cell division
CG010_016270	COG0850	regulation of cytokinetic process
CG010_016275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CG010_016280	COG2186	Transcriptional regulator
CG010_016285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG010_016295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG010_016300	COG1063	alcohol dehydrogenase
CG010_016305	COG1312	Catalyzes the dehydration of D-mannonate
CG010_016325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CG010_016330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CG010_016335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_016345	COG0640	Transcriptional regulator
CG010_016350	COG0625	glutathione transferase activity
CG010_016355	COG4172	Belongs to the ABC transporter superfamily
CG010_016360	COG1921	L-seryl-tRNASec selenium transferase activity
CG010_016375	COG3964	amidohydrolase
CG010_016385	COG0601	transmembrane transport
CG010_016390	COG0747	negative chemotaxis
CG010_016395	COG0438	transferase activity, transferring glycosyl groups
CG010_016430	COG4989	oxidoreductase activity
CG010_016445	COG3842	ATPase activity
CG010_016450	COG1653	transport
CG010_016455	COG1175	transmembrane transport
CG010_016460	COG0395	ABC-type sugar transport system, permease component
CG010_016465	COG1501	Belongs to the glycosyl hydrolase 31 family
CG010_016475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_016480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG010_016485	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CG010_016490	COG0352	thiamine-phosphate diphosphorylase activity
CG010_016495	COG0351	phosphomethylpyrimidine kinase
CG010_016505	COG1522	sequence-specific DNA binding
CG010_016510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CG010_016515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_016530	COG2204	response regulator
CG010_016535	COG4191	Histidine kinase
CG010_016540	COG1301	dicarboxylic acid transport
CG010_016545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG010_016550	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_016580	COG1215	transferase activity, transferring glycosyl groups
CG010_016590	COG2942	2-epimerase
CG010_016615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG010_016625	COG2197	response regulator
CG010_016655	COG3307	-O-antigen
CG010_016660	COG1596	polysaccharide export
CG010_016665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CG010_016685	COG0840	transmembrane signaling receptor activity
CG010_016690	COG1376	ErfK ybiS ycfS ynhG family protein
CG010_016700	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_016710	COG2094	Belongs to the DNA glycosylase MPG family
CG010_016725	COG1609	Transcriptional regulator
CG010_016730	COG1653	transport
CG010_016745	COG3842	ATPase activity
CG010_016755	COG0673	inositol 2-dehydrogenase activity
CG010_016760	COG0602	queuosine metabolic process
CG010_016765	COG0720	synthase
CG010_016770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CG010_016775	COG0673	inositol 2-dehydrogenase activity
CG010_016790	COG0395	ABC-type sugar transport system, permease component
CG010_016820	COG0583	DNA-binding transcription factor activity
CG010_016825	COG0281	malic enzyme
CG010_016825	COG0280	phosphate acetyltransferase
CG010_016840	COG0765	amino acid transport
CG010_016845	COG1126	abc transporter atp-binding protein
CG010_016850	COG2079	MmgE PrpD family protein
CG010_016865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_016885	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CG010_016895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CG010_016900	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CG010_016905	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_016910	COG1129	ABC transporter
CG010_016925	COG1473	amidohydrolase
CG010_016930	COG0747	negative chemotaxis
CG010_016950	COG0601	transmembrane transport
CG010_016960	COG1446	asparaginase
CG010_016975	COG0747	negative chemotaxis
CG010_017000	COG0601	transmembrane transport
CG010_017005	COG2197	response regulator
CG010_017010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG010_017015	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG010_017025	COG3842	ATPase activity
CG010_017030	COG0395	ABC-type sugar transport system, permease component
CG010_017035	COG1175	transmembrane transport
CG010_017045	COG0673	inositol 2-dehydrogenase activity
CG010_017050	COG0673	inositol 2-dehydrogenase activity
CG010_017070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_017075	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CG010_017095	COG1595	DNA-templated transcription, initiation
CG010_017100	COG1120	ATPase activity
CG010_017105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_017120	COG2226	methyltransferase
CG010_017130	COG1120	ATPase activity
CG010_017135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_017180	COG1012	belongs to the aldehyde dehydrogenase family
CG010_017185	COG0473	3-isopropylmalate dehydrogenase activity
CG010_017190	COG1012	belongs to the aldehyde dehydrogenase family
CG010_017195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_017230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_017235	COG4172	Belongs to the ABC transporter superfamily
CG010_017240	COG1522	sequence-specific DNA binding
CG010_017250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_017265	COG0583	DNA-binding transcription factor activity
CG010_017280	COG1126	abc transporter atp-binding protein
CG010_017290	COG1473	amidohydrolase
CG010_017295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_017300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_017305	COG1959	2 iron, 2 sulfur cluster binding
CG010_017315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG010_017320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_017350	COG1960	acyl-CoA dehydrogenase activity
CG010_017360	COG0747	negative chemotaxis
CG010_017375	COG0444	Belongs to the ABC transporter superfamily
CG010_017385	COG0667	Aldo Keto reductase
CG010_017395	COG0583	DNA-binding transcription factor activity
CG010_017405	COG4166	transmembrane transport
CG010_017420	COG0747	negative chemotaxis
CG010_017425	COG1473	amidohydrolase
CG010_017430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_017450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_017460	COG1733	regulation of RNA biosynthetic process
CG010_017465	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_017595	COG4373	Mu-like prophage FluMu protein gp28
CG010_017600	COG4383	Mu-like prophage protein gp29
CG010_017605	COG2369	cell adhesion
CG010_017735	COG4608	Belongs to the ABC transporter superfamily
CG010_017740	COG0444	Belongs to the ABC transporter superfamily
CG010_017750	COG0601	transmembrane transport
CG010_017760	COG2186	Transcriptional regulator
CG010_017775	COG0300	oxidoreductase activity
CG010_017785	COG3453	Protein conserved in bacteria
CG010_017785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG010_017790	COG0640	Transcriptional regulator
CG010_017800	COG2391	methyltransferase activity
CG010_017805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CG010_017825	COG0022	dehydrogenase e1 component
CG010_017835	COG1960	acyl-CoA dehydrogenase activity
CG010_017840	COG0183	Belongs to the thiolase family
CG010_017850	COG1960	acyl-CoA dehydrogenase activity
CG010_017855	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG010_017875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CG010_017880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CG010_017885	COG4952	isomerase
CG010_017890	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_017890	COG3347	Dehydrogenase
CG010_017895	COG1349	DNA-binding transcription factor activity
CG010_017910	COG1129	ABC transporter
CG010_017915	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_017920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_017925	COG3254	rhamnose metabolic process
CG010_017940	COG2264	protein methyltransferase activity
CG010_017945	COG5001	Diguanylate cyclase
CG010_017960	COG4335	DNA alkylation repair
CG010_017965	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG010_017970	COG4208	sulfate ABC transporter
CG010_017980	COG4150	thiosulfate binding
CG010_017985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CG010_018000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG010_018010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG010_018020	COG1040	competence protein
CG010_018025	COG2226	methyltransferase
CG010_018040	COG0494	nUDIX hydrolase
CG010_018050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CG010_018055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CG010_018060	COG0653	protein targeting
CG010_018065	COG0697	spore germination
CG010_018130	COG2244	polysaccharide biosynthetic process
CG010_018145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CG010_018155	COG3206	protein involved in exopolysaccharide biosynthesis
CG010_018155	COG0489	protein tyrosine kinase activity
CG010_018175	COG0438	transferase activity, transferring glycosyl groups
CG010_018180	COG0438	transferase activity, transferring glycosyl groups
CG010_018195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CG010_018200	COG2273	Hydrolase Family 16
CG010_018200	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CG010_018215	COG3842	ATPase activity
CG010_018220	COG3833	ABC-type maltose transport systems, permease component
CG010_018275	COG1396	sequence-specific DNA binding
CG010_018285	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CG010_018290	COG1129	ABC transporter
CG010_018295	COG4214	carbohydrate transport
CG010_018300	COG4213	ABC transporter substrate-binding protein
CG010_018340	COG0625	glutathione transferase activity
CG010_018345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CG010_018350	COG1396	sequence-specific DNA binding
CG010_018350	COG3800	Transcriptional regulator
CG010_018360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG010_018370	COG0300	oxidoreductase activity
CG010_018380	COG2096	Adenosyltransferase
CG010_018390	COG2086	electron transfer activity
CG010_018400	COG1250	3-hydroxyacyl-CoA dehydrogenase
CG010_018410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CG010_018415	COG0165	Argininosuccinate lyase
CG010_018450	COG2884	Cell division ATP-binding protein ftsE
CG010_018470	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CG010_018480	COG0287	Prephenate dehydrogenase
CG010_018485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CG010_018490	COG2226	methyltransferase
CG010_018495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CG010_018515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CG010_018520	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CG010_018560	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CG010_018565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CG010_018580	COG4974	Belongs to the 'phage' integrase family
CG010_018585	COG0825	malonyl-CoA metabolic process
CG010_018590	COG3034	peptidoglycan biosynthetic process
CG010_018595	COG0425	Belongs to the sulfur carrier protein TusA family
CG010_018595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CG010_018605	COG0523	cobalamin synthesis protein
CG010_018610	COG1686	Belongs to the peptidase S11 family
CG010_018615	COG1473	amidohydrolase
CG010_018625	COG4953	penicillin-binding protein 1C
CG010_018630	COG2373	Large extracellular alpha-helical protein
CG010_018635	COG2835	tetraacyldisaccharide 4'-kinase activity
CG010_018665	COG0482	sulfurtransferase activity
CG010_018680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG010_018695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CG010_018700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CG010_018705	COG0037	tRNA processing
CG010_018715	COG2885	chlorophyll binding
CG010_018720	COG0823	Involved in the tonB-independent uptake of proteins
CG010_018740	COG0824	Thioesterase
CG010_018750	COG0494	nUDIX hydrolase
CG010_018765	COG2255	four-way junction helicase activity
CG010_018770	COG0632	four-way junction helicase activity
CG010_018775	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CG010_018780	COG0840	transmembrane signaling receptor activity
CG010_018785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_018790	COG0217	transcriptional regulatory protein
CG010_018805	COG1692	metallophosphoesterase
CG010_018815	COG1253	flavin adenine dinucleotide binding
CG010_018865	COG0126	phosphoglycerate kinase activity
CG010_018870	COG3588	fructose-bisphosphate aldolase
CG010_018890	COG0254	rRNA binding
CG010_018895	COG1132	(ABC) transporter
CG010_018915	COG0483	inositol monophosphate 1-phosphatase activity
CG010_018945	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CG010_018950	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CG010_018955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CG010_018960	COG0457	Tetratricopeptide repeat
CG010_018965	COG3750	Belongs to the UPF0335 family
CG010_018985	COG0469	pyruvate kinase activity
CG010_018990	COG3108	Peptidase M15
CG010_018995	COG2204	response regulator
CG010_019000	COG1164	Oligoendopeptidase f
CG010_019005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CG010_019010	COG3706	GGDEF domain
CG010_019010	COG0745	RESPONSE REGULATOR receiver
CG010_019015	COG5310	Homospermidine synthase
CG010_019025	COG0737	Belongs to the 5'-nucleotidase family
CG010_019030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CG010_019035	COG0330	HflC and HflK could
CG010_019065	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG010_019070	COG2951	lytic endotransglycosylase activity
CG010_019085	COG2205	protein histidine kinase activity
CG010_019095	COG0069	glutamate synthase activity
CG010_019095	COG0067	glutamate synthase
CG010_019095	COG0070	glutamate synthase
CG010_019110	COG2205	protein histidine kinase activity
CG010_019115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CG010_019120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CG010_019125	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CG010_019135	COG0252	asparaginase activity
CG010_019145	COG1027	Aspartate ammonia-lyase
CG010_019150	COG2186	Transcriptional regulator
CG010_019190	COG4176	ABC-type proline glycine betaine transport system permease component
CG010_019195	COG0517	IMP dehydrogenase activity
CG010_019195	COG4175	Glycine betaine
CG010_019200	COG2986	histidine ammonia-lyase
CG010_019205	COG1609	Transcriptional regulator
CG010_019225	COG1082	Xylose isomerase domain protein TIM barrel
CG010_019230	COG0673	inositol 2-dehydrogenase activity
CG010_019235	COG1082	Xylose isomerase domain protein TIM barrel
CG010_019260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG010_019305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_019310	COG4172	Belongs to the ABC transporter superfamily
CG010_019320	COG0601	transmembrane transport
CG010_019325	COG0747	negative chemotaxis
CG010_019335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CG010_019340	COG1454	alcohol dehydrogenase
CG010_019345	COG2186	Transcriptional regulator
CG010_019360	COG1607	acyl-coa hydrolase
CG010_019385	COG2308	Evidence 4 Homologs of previously reported genes of
CG010_019385	COG2307	Protein conserved in bacteria
CG010_019400	COG0488	(ABC) transporter
CG010_019405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG010_019410	COG2186	Transcriptional regulator
CG010_019425	COG1175	transmembrane transport
CG010_019430	COG0395	ABC-type sugar transport system, permease component
CG010_019440	COG3842	ATPase activity
CG010_019460	COG2171	N-acyltransferase activity
CG010_019465	COG1304	FMN binding
CG010_019480	COG1063	alcohol dehydrogenase
CG010_019485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG010_019490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_019500	COG0765	amino acid transport
CG010_019505	COG0765	amino acid transport
CG010_019510	COG4221	oxidoreductase activity
CG010_019515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG010_019520	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_019525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG010_019540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG010_019555	COG0697	spore germination
CG010_019560	COG0697	spore germination
CG010_019565	COG0511	ligase activity, forming carbon-carbon bonds
CG010_019570	COG0439	Biotin carboxylase
CG010_019580	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG010_019585	COG1984	allophanate hydrolase subunit 2
CG010_019590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG010_019595	COG3842	ATPase activity
CG010_019605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CG010_019610	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_019630	COG0840	transmembrane signaling receptor activity
CG010_019635	COG1070	Carbohydrate kinase
CG010_019640	COG1830	Aldolase
CG010_019645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG010_019650	COG0667	Aldo Keto reductase
CG010_019660	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_019665	COG1129	ABC transporter
CG010_019715	COG0071	Belongs to the small heat shock protein (HSP20) family
CG010_019730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG010_019745	COG0395	ABC-type sugar transport system, permease component
CG010_019760	COG3842	ATPase activity
CG010_019775	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CG010_019775	COG1648	precorrin-2 dehydrogenase activity
CG010_019780	COG0243	molybdopterin cofactor binding
CG010_019795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CG010_019800	COG1116	anion transmembrane transporter activity
CG010_019805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_019810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG010_019820	COG3707	response regulator
CG010_019825	COG1802	Transcriptional regulator
CG010_019830	COG1914	H( )-stimulated, divalent metal cation uptake system
CG010_019835	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CG010_019840	COG4336	lyase activity
CG010_019845	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CG010_019850	COG4770	biotin carboxylase activity
CG010_019855	COG0366	Alpha amylase catalytic
CG010_019865	COG4771	TonB-dependent receptor
CG010_019870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CG010_019890	COG1414	Transcriptional regulator
CG010_019895	COG1475	DNA binding
CG010_019900	COG1192	Involved in chromosome partitioning
CG010_019930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CG010_019940	COG2986	histidine ammonia-lyase
CG010_019945	COG1228	amidohydrolase
CG010_019950	COG0402	S-adenosylhomocysteine deaminase activity
CG010_020000	COG4172	Belongs to the ABC transporter superfamily
CG010_020005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_020010	COG0601	transmembrane transport
CG010_020015	COG4166	transmembrane transport
CG010_020020	COG0395	ABC-type sugar transport system, permease component
CG010_020040	COG1566	PFAM secretion protein HlyD family protein
CG010_020060	COG2207	Transcriptional regulator
CG010_020065	COG1309	transcriptional regulator
CG010_020070	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_020095	COG1846	Transcriptional regulator
CG010_020100	COG0583	DNA-binding transcription factor activity
CG010_020105	COG2828	Protein conserved in bacteria
CG010_020120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_020135	COG0840	transmembrane signaling receptor activity
CG010_020155	COG1215	transferase activity, transferring glycosyl groups
CG010_020185	COG0583	DNA-binding transcription factor activity
CG010_020190	COG0346	lactoylglutathione lyase activity
CG010_020205	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CG010_020225	COG0583	DNA-binding transcription factor activity
CG010_020230	COG0477	Major facilitator Superfamily
CG010_020240	COG2205	protein histidine kinase activity
CG010_020245	COG0745	RESPONSE REGULATOR receiver
CG010_020250	COG0671	phosphoesterase, PA-phosphatase related
CG010_020305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CG010_020310	COG0156	8-amino-7-oxononanoate synthase activity
CG010_020315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CG010_020320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CG010_020325	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CG010_020350	COG0697	spore germination
CG010_020355	COG0673	inositol 2-dehydrogenase activity
CG010_020380	COG0477	Major facilitator Superfamily
CG010_020385	COG0642	Histidine kinase
CG010_020390	COG0745	RESPONSE REGULATOR receiver
CG010_020395	COG2194	sulfuric ester hydrolase activity
CG010_020405	COG0583	DNA-binding transcription factor activity
CG010_020410	COG4774	siderophore transport
CG010_020425	COG1120	ATPase activity
CG010_020435	COG3474	cytochrome
CG010_020440	COG2137	regulation of response to DNA damage stimulus
CG010_020445	COG3386	PFAM SMP-30 Gluconolaconase
CG010_020455	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_020460	COG1129	ABC transporter
CG010_020465	COG1879	ABC-type sugar transport system periplasmic component
CG010_020475	COG4585	Histidine kinase
CG010_020480	COG2197	response regulator
CG010_020490	COG2133	pyrroloquinoline quinone binding
CG010_020500	COG0500	methyltransferase
CG010_020505	COG0564	pseudouridine synthase activity
CG010_020520	COG3448	diguanylate cyclase activity
CG010_020520	COG4175	Glycine betaine
CG010_020525	COG4176	ABC-type proline glycine betaine transport system permease component
CG010_020540	COG4191	Histidine kinase
CG010_020540	COG0784	Response regulator, receiver
CG010_020545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CG010_020550	COG0489	protein tyrosine kinase activity
CG010_020550	COG3206	protein involved in exopolysaccharide biosynthesis
CG010_020555	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CG010_020560	COG1215	transferase activity, transferring glycosyl groups
CG010_020565	COG1215	transferase activity, transferring glycosyl groups
CG010_020570	COG1215	transferase activity, transferring glycosyl groups
CG010_020575	COG0438	transferase activity, transferring glycosyl groups
CG010_020580	COG2273	Hydrolase Family 16
CG010_020585	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CG010_020590	COG2244	polysaccharide biosynthetic process
CG010_020595	COG0463	Glycosyl transferase, family 2
CG010_020600	COG2327	Polysaccharide pyruvyl transferase
CG010_020605	COG1215	transferase activity, transferring glycosyl groups
CG010_020625	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CG010_020635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_020650	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG010_020650	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG010_020675	COG1523	belongs to the glycosyl hydrolase 13 family
CG010_020680	COG0033	Phosphoglucomutase
CG010_020685	COG0297	glycogen (starch) synthase activity
CG010_020690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CG010_020695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CG010_020700	COG0058	SHG alpha-glucan phosphorylase activity
CG010_020715	COG1794	racemase activity, acting on amino acids and derivatives
CG010_020720	COG1522	sequence-specific DNA binding
CG010_020735	COG2084	Dehydrogenase
CG010_020740	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_020745	COG1063	alcohol dehydrogenase
CG010_020755	COG4988	ABC transporter
CG010_020760	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CG010_020770	COG1294	oxidase, subunit
CG010_020800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CG010_020805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CG010_020835	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CG010_020840	COG0539	negative regulation of cytoplasmic translation
CG010_020870	COG4221	oxidoreductase activity
CG010_020885	COG0747	negative chemotaxis
CG010_020890	COG0601	transmembrane transport
CG010_020895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_020900	COG0444	Belongs to the ABC transporter superfamily
CG010_020905	COG4608	Belongs to the ABC transporter superfamily
CG010_020910	COG0246	Mannitol dehydrogenase
CG010_020925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_020945	COG0410	ABC transporter
CG010_020950	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG010_020970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CG010_020975	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_020995	COG4993	Dehydrogenase
CG010_021000	COG3685	Protein conserved in bacteria
CG010_021010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_021010	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CG010_021030	COG0693	protein deglycase activity
CG010_021055	COG0189	ligase activity
CG010_021060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CG010_021065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CG010_021075	COG0435	Glutathione S-transferase
CG010_021080	COG0583	DNA-binding transcription factor activity
CG010_021085	COG1012	belongs to the aldehyde dehydrogenase family
CG010_021090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CG010_021095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CG010_021100	COG1116	anion transmembrane transporter activity
CG010_021115	COG1522	sequence-specific DNA binding
CG010_021130	COG0784	Response regulator, receiver
CG010_021150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CG010_021165	COG0019	diaminopimelate decarboxylase activity
CG010_021185	COG0527	aspartate kinase activity
CG010_021195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CG010_021200	COG2890	protein-(glutamine-N5) methyltransferase activity
CG010_021215	COG0542	response to heat
CG010_021220	COG0741	lytic transglycosylase activity
CG010_021220	COG1196	nuclear chromosome segregation
CG010_021220	COG0739	heme binding
CG010_021270	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CG010_021280	COG1280	lysine exporter protein (LysE YggA)
CG010_021295	COG1309	transcriptional regulator
CG010_021300	COG4221	oxidoreductase activity
CG010_021305	COG1902	pentaerythritol trinitrate reductase activity
CG010_021310	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_021350	COG1278	Cold shock
CG010_021370	COG0753	catalase activity
CG010_021395	COG3920	Histidine kinase
CG010_021405	COG1280	lysine exporter protein (LysE YggA)
CG010_021425	COG0583	DNA-binding transcription factor activity
CG010_021460	COG0583	DNA-binding transcription factor activity
CG010_021470	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_021475	COG1846	Transcriptional regulator
CG010_021495	COG2186	Transcriptional regulator
CG010_021505	COG1126	abc transporter atp-binding protein
CG010_021520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_021540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_021565	COG0405	Gamma-glutamyltransferase
CG010_021575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CG010_021595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_021600	COG0747	negative chemotaxis
CG010_021605	COG0747	negative chemotaxis
CG010_021615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_021625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_021635	COG1129	ABC transporter
CG010_021640	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_021645	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_021670	COG0667	Aldo Keto reductase
CG010_021685	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_021690	COG1129	ABC transporter
CG010_021695	COG4213	ABC transporter substrate-binding protein
CG010_021715	COG4608	Belongs to the ABC transporter superfamily
CG010_021720	COG0444	Belongs to the ABC transporter superfamily
CG010_021730	COG0601	transmembrane transport
CG010_021735	COG0747	negative chemotaxis
CG010_021760	COG0765	amino acid transport
CG010_021765	COG4597	amino acid ABC transporter
CG010_021770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_021785	COG3177	Filamentation induced by cAMP protein fic
CG010_021810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_021820	COG3501	Rhs element vgr protein
CG010_021840	COG3209	COG3209 Rhs family protein
CG010_021860	COG0745	RESPONSE REGULATOR receiver
CG010_021870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_021875	COG1136	(ABC) transporter
CG010_021875	COG0577	efflux transmembrane transporter activity
CG010_021885	COG1733	regulation of RNA biosynthetic process
CG010_021935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG010_021940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CG010_021950	COG1566	PFAM secretion protein HlyD family protein
CG010_021960	COG0625	glutathione transferase activity
CG010_021965	COG4221	oxidoreductase activity
CG010_021975	COG2376	Dihydroxyacetone kinase
CG010_021980	COG1522	sequence-specific DNA binding
CG010_022000	COG0431	NADPH-dependent FMN reductase
CG010_022010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CG010_022020	COG4172	Belongs to the ABC transporter superfamily
CG010_022025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_022050	COG0277	FAD linked oxidase domain protein
CG010_022070	COG0778	Nitroreductase
CG010_022100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CG010_022130	COG2318	DinB family
CG010_022135	COG0583	DNA-binding transcription factor activity
CG010_022150	COG1335	isochorismatase
CG010_022160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG010_022175	COG3842	ATPase activity
CG010_022180	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_022185	COG1177	transmembrane transport
CG010_022190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CG010_022200	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CG010_022215	COG1120	ATPase activity
CG010_022220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_022225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_022230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CG010_022235	COG1629	transport
CG010_022235	COG4774	siderophore transport
CG010_022240	COG4702	Belongs to the UPF0303 family
CG010_022260	COG1024	Enoyl-CoA hydratase
CG010_022270	COG1653	transport
CG010_022285	COG3842	ATPase activity
CG010_022310	COG3474	cytochrome
CG010_022315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CG010_022320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CG010_022325	COG1845	cytochrome c oxidase, subunit III
CG010_022350	COG0577	efflux transmembrane transporter activity
CG010_022350	COG1136	(ABC) transporter
CG010_022370	COG0745	RESPONSE REGULATOR receiver
CG010_022405	COG3842	ATPase activity
CG010_022415	COG1177	transmembrane transport
CG010_022420	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_022435	COG1940	carbohydrate kinase activity
CG010_022455	COG1069	ribulokinase activity
CG010_022460	COG1349	DNA-binding transcription factor activity
CG010_022465	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_022490	COG0395	ABC-type sugar transport system, permease component
CG010_022500	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_022515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CG010_022525	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CG010_022535	COG0477	Major facilitator Superfamily
CG010_022590	COG1733	regulation of RNA biosynthetic process
CG010_022630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CG010_022635	COG3938	Belongs to the proline racemase family
CG010_022640	COG4176	ABC-type proline glycine betaine transport system permease component
CG010_022650	COG4175	Glycine betaine
CG010_022650	COG3448	diguanylate cyclase activity
CG010_022660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_022665	COG1012	belongs to the aldehyde dehydrogenase family
CG010_022670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_022680	COG0047	phosphoribosylformylglycinamidine synthase activity
CG010_022685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_022695	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG010_022695	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG010_022705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CG010_022725	COG1309	transcriptional regulator
CG010_022740	COG1136	(ABC) transporter
CG010_022755	COG1063	alcohol dehydrogenase
CG010_022765	COG1879	ABC-type sugar transport system periplasmic component
CG010_022775	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_022795	COG0477	Major facilitator Superfamily
CG010_022900	COG3501	Rhs element vgr protein
CG010_022925	COG3300	MHYT domain
CG010_022925	COG5001	Diguanylate cyclase
CG010_022950	COG1253	flavin adenine dinucleotide binding
CG010_022965	COG3842	ATPase activity
CG010_022970	COG0395	ABC-type sugar transport system, permease component
CG010_022975	COG1175	transmembrane transport
CG010_022980	COG1653	transport
CG010_022990	COG0673	inositol 2-dehydrogenase activity
CG010_022995	COG1609	Transcriptional regulator
CG010_023010	COG0583	DNA-binding transcription factor activity
CG010_023020	COG1879	ABC-type sugar transport system periplasmic component
CG010_023025	COG1129	ABC transporter
CG010_023030	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_023035	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_023040	COG1609	Transcriptional regulator
CG010_023050	COG0673	inositol 2-dehydrogenase activity
CG010_023110	COG0714	Associated with various cellular activities
CG010_023115	COG3256	nitric oxide reductase
CG010_023150	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CG010_023155	COG3189	MarR family transcriptional regulator
CG010_023200	COG4459	periplasmic nitrate reductase
CG010_023215	COG0243	molybdopterin cofactor binding
CG010_023225	COG3005	denitrification pathway
CG010_023240	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_023245	COG1535	isochorismatase
CG010_023245	COG3433	isochorismatase activity
CG010_023250	COG1021	2,3-dihydroxybenzoate-AMP ligase
CG010_023255	COG1169	isochorismate synthase
CG010_023265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG010_023265	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CG010_023270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CG010_023280	COG2375	cellular response to nickel ion
CG010_023290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_023295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_023315	COG1629	transport
CG010_023315	COG4774	siderophore transport
CG010_023320	COG1960	acyl-CoA dehydrogenase activity
CG010_023325	COG0583	DNA-binding transcription factor activity
CG010_023330	COG1609	Transcriptional regulator
CG010_023340	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_023350	COG3842	ATPase activity
CG010_023360	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CG010_023365	COG0583	DNA-binding transcription factor activity
CG010_023370	COG2814	Major facilitator Superfamily
CG010_023375	COG1473	amidohydrolase
CG010_023390	COG0747	negative chemotaxis
CG010_023395	COG0601	transmembrane transport
CG010_023405	COG0444	Belongs to the ABC transporter superfamily
CG010_023410	COG4608	Belongs to the ABC transporter superfamily
CG010_023415	COG0583	DNA-binding transcription factor activity
CG010_023420	COG0747	negative chemotaxis
CG010_023430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_023435	COG0154	amidase activity
CG010_023440	COG0693	protein deglycase activity
CG010_023450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_023455	COG0601	transmembrane transport
CG010_023465	COG1473	amidohydrolase
CG010_023470	COG4172	Belongs to the ABC transporter superfamily
CG010_023475	COG2390	Transcriptional regulator
CG010_023485	COG1175	transmembrane transport
CG010_023495	COG0395	ABC-type sugar transport system, permease component
CG010_023545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CG010_023565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CG010_023570	COG1414	Transcriptional regulator
CG010_023575	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_023585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG010_023590	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CG010_023595	COG1121	(ABC) transporter
CG010_023600	COG0803	Belongs to the bacterial solute-binding protein 9 family
CG010_023610	COG1752	Esterase of the alpha-beta hydrolase superfamily
CG010_023615	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CG010_023620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CG010_023625	COG0471	metal ion transport
CG010_023625	COG3273	potassium ion transport
CG010_023630	COG1253	flavin adenine dinucleotide binding
CG010_023635	COG1309	transcriptional regulator
CG010_023655	COG1609	Transcriptional regulator
CG010_023660	COG1070	Carbohydrate kinase
CG010_023670	COG2115	Belongs to the xylose isomerase family
CG010_023690	COG0778	Nitroreductase
CG010_023695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CG010_023700	COG2011	ABC-type metal ion transport system permease component
CG010_023710	COG3300	MHYT domain
CG010_023710	COG5001	Diguanylate cyclase
CG010_023730	COG0800	Aldolase
CG010_023755	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CG010_023800	COG0523	cobalamin synthesis protein
CG010_023810	COG1846	Transcriptional regulator
CG010_023815	COG1609	Transcriptional regulator
CG010_023820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG010_023830	COG3718	enzyme involved in inositol metabolism
CG010_023840	COG3962	Belongs to the TPP enzyme family
CG010_023845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_023860	COG0411	ABC transporter
CG010_023875	COG0683	leucine binding
CG010_023890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_023900	COG0747	negative chemotaxis
CG010_023905	COG4172	Belongs to the ABC transporter superfamily
CG010_023930	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CG010_023935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CG010_023940	COG1126	abc transporter atp-binding protein
CG010_023945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_023950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_023955	COG0765	amino acid transport
CG010_023960	COG0765	amino acid transport
CG010_023965	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CG010_023970	COG3485	protocatechuate 3,4-dioxygenase
CG010_023975	COG3485	protocatechuate 3,4-dioxygenase
CG010_023980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CG010_023990	COG0583	DNA-binding transcription factor activity
CG010_024005	COG1414	Transcriptional regulator
CG010_024015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CG010_024020	COG0183	Belongs to the thiolase family
CG010_024025	COG1609	Transcriptional regulator
CG010_024040	COG1082	Xylose isomerase domain protein TIM barrel
CG010_024045	COG0673	inositol 2-dehydrogenase activity
CG010_024055	COG1609	Transcriptional regulator
CG010_024060	COG0395	ABC-type sugar transport system, permease component
CG010_024065	COG1175	transmembrane transport
CG010_024070	COG3842	ATPase activity
CG010_024080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CG010_024100	COG2814	Major facilitator Superfamily
CG010_024105	COG4774	siderophore transport
CG010_024110	COG3712	iron ion homeostasis
CG010_024120	COG1940	carbohydrate kinase activity
CG010_024125	COG0584	glycerophosphoryl diester phosphodiesterase
CG010_024130	COG0300	oxidoreductase activity
CG010_024165	COG0667	Aldo Keto reductase
CG010_024170	COG0583	DNA-binding transcription factor activity
CG010_024180	COG1132	(ABC) transporter
CG010_024195	COG1216	Glycosyl transferase, family 2
CG010_024195	COG1442	glycosyl transferase family 8
CG010_024200	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CG010_024210	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CG010_024230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CG010_024235	COG3754	Rhamnan synthesis protein F
CG010_024250	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CG010_024255	COG1091	dTDP-4-dehydrorhamnose reductase activity
CG010_024260	COG1088	dTDP-glucose 4,6-dehydratase activity
CG010_024265	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CG010_024270	COG0210	DNA helicase
CG010_024280	COG1609	Transcriptional regulator
CG010_024285	COG0446	pyridine nucleotide-disulphide oxidoreductase
CG010_024285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG010_024300	COG0395	ABC-type sugar transport system, permease component
CG010_024305	COG3842	ATPase activity
CG010_024315	COG0444	Belongs to the ABC transporter superfamily
CG010_024320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_024325	COG0601	transmembrane transport
CG010_024330	COG2186	Transcriptional regulator
CG010_024340	COG0747	negative chemotaxis
CG010_024350	COG5001	Diguanylate cyclase
CG010_024350	COG3300	MHYT domain
CG010_024355	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_024365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CG010_024375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CG010_024380	COG0306	phosphate transporter
CG010_024385	COG1392	Phosphate transport regulator
CG010_024400	COG1566	PFAM secretion protein HlyD family protein
CG010_024405	COG0745	RESPONSE REGULATOR receiver
CG010_024410	COG2205	protein histidine kinase activity
CG010_024425	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CG010_024435	COG2207	Transcriptional regulator
CG010_024440	COG4774	siderophore transport
CG010_024450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_024455	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_024460	COG1120	ATPase activity
CG010_024465	COG0583	DNA-binding transcription factor activity
CG010_024475	COG3119	arylsulfatase activity
CG010_024480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CG010_024485	COG3842	ATPase activity
CG010_024490	COG0165	Argininosuccinate lyase
CG010_024495	COG0395	ABC-type sugar transport system, permease component
CG010_024500	COG1175	transmembrane transport
CG010_024505	COG2182	Extracellular solute-binding protein
CG010_024510	COG1940	carbohydrate kinase activity
CG010_024535	COG1486	melibiose metabolic process
CG010_024540	COG0747	negative chemotaxis
CG010_024545	COG0601	transmembrane transport
CG010_024550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_024555	COG4172	Belongs to the ABC transporter superfamily
CG010_024560	COG1486	melibiose metabolic process
CG010_024565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CG010_024570	COG1129	ABC transporter
CG010_024570	COG0842	Transport permease protein
CG010_024575	COG0842	Transport permease protein
CG010_024590	COG0784	Response regulator, receiver
CG010_024595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CG010_024605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_024610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CG010_024630	COG0765	amino acid transport
CG010_024640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CG010_024650	COG3938	Belongs to the proline racemase family
CG010_024665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_024675	COG0765	amino acid transport
CG010_024685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CG010_024700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CG010_024720	COG3383	formate dehydrogenase (NAD+) activity
CG010_024735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CG010_024745	COG2186	Transcriptional regulator
CG010_024750	COG0747	negative chemotaxis
CG010_024755	COG0601	transmembrane transport
CG010_024760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_024765	COG4172	Belongs to the ABC transporter superfamily
CG010_024770	COG4948	Mandelate Racemase Muconate Lactonizing
CG010_024780	COG2186	Transcriptional regulator
CG010_024785	COG0747	negative chemotaxis
CG010_024790	COG0601	transmembrane transport
CG010_024800	COG0405	Gamma-glutamyltransferase
CG010_024810	COG0483	inositol monophosphate 1-phosphatase activity
CG010_024820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CG010_024845	COG3237	CsbD-like
CG010_024855	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CG010_024860	COG3181	Tripartite tricarboxylate transporter family receptor
CG010_024865	COG5265	(ABC) transporter
CG010_024870	COG0488	(ABC) transporter
CG010_024895	COG1049	propionate catabolic process, 2-methylcitrate cycle
CG010_024900	COG0110	maltose O-acetyltransferase activity
CG010_024910	COG1063	alcohol dehydrogenase
CG010_024915	COG3284	Transcriptional regulator
CG010_024935	COG1129	ABC transporter
CG010_024940	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_024945	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_024950	COG1082	Xylose isomerase domain protein TIM barrel
CG010_024955	COG0572	uridine kinase
CG010_024960	COG1082	Xylose isomerase domain protein TIM barrel
CG010_024990	COG4178	(ABC) transporter
CG010_025030	COG0640	Transcriptional regulator
CG010_025065	COG1475	DNA binding
CG010_025070	COG0640	Transcriptional regulator
CG010_025085	COG1126	abc transporter atp-binding protein
CG010_025090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CG010_025130	COG3239	Fatty acid desaturase
CG010_025140	COG1278	Cold shock
CG010_025225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CG010_025225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
CG010_025265	COG1132	(ABC) transporter
CG010_025275	COG0640	Transcriptional regulator
CG010_025305	COG4977	sequence-specific DNA binding
CG010_025310	COG2211	Major facilitator Superfamily
CG010_025315	COG2807	transmembrane transport
CG010_025320	COG1846	Transcriptional regulator
CG010_025335	COG2814	Major facilitator Superfamily
CG010_025365	COG3443	Belongs to the bacterial solute-binding protein 9 family
CG010_025380	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CG010_025385	COG0583	DNA-binding transcription factor activity
CG010_025400	COG0071	Belongs to the small heat shock protein (HSP20) family
CG010_025450	COG3838	Conjugal transfer protein Trbc
CG010_025455	COG3702	type iv secretory pathway
CG010_025460	COG3451	type IV secretory pathway VirB4
CG010_025475	COG3704	protein secretion by the type IV secretion system
CG010_025485	COG3736	Type IV secretory pathway, component VirB8
CG010_025490	COG3504	Conjugal transfer protein
CG010_025495	COG2948	multi-organism process
CG010_025500	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CG010_025605	COG3831	ATPase activity
CG010_025620	COG3505	Type IV secretory pathway VirD4
CG010_025645	COG0583	DNA-binding transcription factor activity
CG010_025680	COG0745	RESPONSE REGULATOR receiver
CG010_025705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CG010_025720	COG3842	ATPase activity
CG010_025725	COG4208	sulfate ABC transporter
CG010_025730	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_025750	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CG010_025755	COG1942	4-Oxalocrotonate Tautomerase
CG010_025765	COG3971	2-oxopent-4-enoate hydratase activity
CG010_025775	COG1414	Transcriptional regulator
CG010_025785	COG1137	ATPase activity
CG010_025800	COG4177	L-phenylalanine transmembrane transporter activity
CG010_025820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CG010_025825	COG1175	transmembrane transport
CG010_025830	COG0395	ABC-type sugar transport system, permease component
CG010_025845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CG010_025850	COG1082	Xylose isomerase domain protein TIM barrel
CG010_025855	COG3842	ATPase activity
CG010_025865	COG1940	carbohydrate kinase activity
CG010_025885	COG0673	inositol 2-dehydrogenase activity
CG010_025915	COG1126	abc transporter atp-binding protein
CG010_025920	COG0765	amino acid transport
CG010_025925	COG0765	amino acid transport
CG010_025935	COG4608	Belongs to the ABC transporter superfamily
CG010_025945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_025960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG010_025965	COG0583	DNA-binding transcription factor activity
CG010_025970	COG2423	ornithine cyclodeaminase activity
CG010_025980	COG1957	nucleoside hydrolase
CG010_026000	COG1335	isochorismatase
CG010_026005	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_026050	COG0583	DNA-binding transcription factor activity
CG010_026055	COG1902	pentaerythritol trinitrate reductase activity
CG010_026060	COG0583	DNA-binding transcription factor activity
CG010_026065	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_026075	COG1335	isochorismatase
CG010_026080	COG0583	DNA-binding transcription factor activity
CG010_026090	COG1695	Transcriptional regulator
CG010_026155	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG010_026160	COG0410	ABC transporter
CG010_026175	COG2207	Transcriptional regulator
CG010_026220	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_026235	COG1802	Transcriptional regulator
CG010_026240	COG3485	protocatechuate 3,4-dioxygenase
CG010_026245	COG3971	2-oxopent-4-enoate hydratase activity
CG010_026260	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CG010_026265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CG010_026280	COG1063	alcohol dehydrogenase
CG010_026290	COG1960	acyl-CoA dehydrogenase activity
CG010_026295	COG1024	Enoyl-CoA hydratase
CG010_026305	COG1012	belongs to the aldehyde dehydrogenase family
CG010_026310	COG0477	Major facilitator Superfamily
CG010_026330	COG3706	GGDEF domain
CG010_026345	COG1846	Transcriptional regulator
CG010_026360	COG0559	Belongs to the binding-protein-dependent transport system permease family
CG010_026375	COG0410	ABC transporter
CG010_026385	COG1012	belongs to the aldehyde dehydrogenase family
CG010_026395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CG010_026405	COG3386	PFAM SMP-30 Gluconolaconase
CG010_026410	COG3622	Belongs to the hyi family
CG010_026415	COG2084	Dehydrogenase
CG010_026440	COG1940	carbohydrate kinase activity
CG010_026445	COG1172	Belongs to the binding-protein-dependent transport system permease family
CG010_026455	COG1129	ABC transporter
CG010_026470	COG0583	DNA-binding transcription factor activity
CG010_026475	COG2271	Major facilitator Superfamily
CG010_026485	COG2272	Belongs to the type-B carboxylesterase lipase family
CG010_026505	COG1129	ABC transporter
CG010_026530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CG010_026540	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CG010_026560	COG0410	ABC transporter
CG010_026575	COG0583	DNA-binding transcription factor activity
CG010_026580	COG1414	Transcriptional regulator
CG010_026590	COG4948	Mandelate Racemase Muconate Lactonizing
CG010_026600	COG3842	ATPase activity
CG010_026605	COG1175	transmembrane transport
CG010_026610	COG0395	ABC-type sugar transport system, permease component
CG010_026620	COG0477	Major facilitator Superfamily
CG010_026660	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CG010_026680	COG0747	negative chemotaxis
CG010_026690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_026715	COG4215	(ABC) transporter
CG010_026770	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CG010_026775	COG0251	oxidation-reduction process
CG010_026780	COG3547	Transposase (IS116 IS110 IS902 family)
CG010_026815	COG1028	Short-chain dehydrogenase reductase Sdr
CG010_026820	COG1335	isochorismatase
CG010_026830	COG1309	transcriptional regulator
CG010_026835	COG4604	ABC transporter, ATP-binding protein
CG010_026840	COG4605	iron ion homeostasis
CG010_026845	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CG010_026855	COG2132	Multicopper oxidase
CG010_026860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CG010_026865	COG4771	TonB-dependent receptor
CG010_026900	COG1695	Transcriptional regulator
CG010_026940	COG2132	Multicopper oxidase
CG010_026975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CG010_026995	COG1192	Involved in chromosome partitioning
CG010_027000	COG1475	DNA binding
CG010_027005	COG0640	Transcriptional regulator
CG010_027010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CG010_027040	COG2211	Major facilitator Superfamily
CG010_027090	COG4974	Belongs to the 'phage' integrase family
CG010_027095	COG1051	belongs to the nudix hydrolase family
CG010_027140	COG1475	DNA binding
CG010_027165	COG2824	Alkylphosphonate utilization operon protein PhnA
CG010_027185	COG1280	lysine exporter protein (LysE YggA)
CG010_027240	COG0494	nUDIX hydrolase
CG010_027255	COG5489	Protein of unknown function (DUF736)
CG010_027340	COG1283	sodium-dependent phosphate transmembrane transporter activity
CG010_027355	COG0747	negative chemotaxis
CG010_027370	COG0601	transmembrane transport
CG010_027375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CG010_027380	COG0584	glycerophosphoryl diester phosphodiesterase
CG010_027385	COG0483	inositol monophosphate 1-phosphatase activity
CG010_027475	COG3161	chorismate lyase activity
CG010_027765	COG0583	DNA-binding transcription factor activity
CG010_027770	COG0747	negative chemotaxis
CG010_027785	COG0252	asparaginase activity
CG010_027790	COG0583	DNA-binding transcription factor activity
CG010_027800	COG1176	ABC-type spermidine putrescine transport system, permease component I
CG010_027835	COG3701	Conjugal transfer protein
CG010_027840	COG3846	protein secretion by the type IV secretion system
CG010_027850	COG5314	conjugation
CG010_027855	COG3451	type IV secretory pathway VirB4
CG010_027870	COG4962	Type ii secretion system protein e