locus-tag	class	description
FY129_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY129_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY129_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY129_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY129_00025	COG1420	regulation of RNA biosynthetic process
FY129_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY129_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY129_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY129_00050	COG1137	ATPase activity
FY129_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY129_00065	COG0616	signal peptide processing
FY129_00070	COG0776	regulation of translation
FY129_00080	COG0116	Belongs to the methyltransferase superfamily
FY129_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY129_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY129_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY129_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY129_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY129_00115	COG0728	peptidoglycan biosynthetic process
FY129_00125	COG0180	Tryptophanyl-tRNA synthetase
FY129_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY129_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY129_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY129_00165	COG1702	phosphate starvation-inducible protein PhoH
FY129_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY129_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY129_00185	COG1396	sequence-specific DNA binding
FY129_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY129_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY129_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_00210	COG0242	peptide deformylase activity
FY129_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY129_00220	COG0101	tRNA pseudouridine synthase activity
FY129_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY129_00235	COG2171	N-acyltransferase activity
FY129_00245	COG0840	transmembrane signaling receptor activity
FY129_00250	COG1957	nucleoside hydrolase
FY129_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY129_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY129_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY129_00295	COG0706	membrane insertase activity
FY129_00300	COG0594	ribonuclease P activity
FY129_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY129_00310	COG0840	transmembrane signaling receptor activity
FY129_00325	COG2226	methyltransferase
FY129_00330	COG3842	ATPase activity
FY129_00335	COG1175	transmembrane transport
FY129_00340	COG0395	ABC-type sugar transport system, permease component
FY129_00355	COG0427	acetyl-CoA hydrolase
FY129_00365	COG3938	Belongs to the proline racemase family
FY129_00370	COG0418	dihydroorotase activity
FY129_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY129_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY129_00400	COG0166	Belongs to the GPI family
FY129_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY129_00410	COG3842	ATPase activity
FY129_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY129_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY129_00425	COG4774	siderophore transport
FY129_00470	COG2326	polyphosphate kinase activity
FY129_00475	COG5002	protein histidine kinase activity
FY129_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY129_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY129_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY129_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY129_00505	COG0745	RESPONSE REGULATOR receiver
FY129_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY129_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY129_00530	COG2967	ApaG domain
FY129_00545	COG0717	Belongs to the dCTP deaminase family
FY129_00555	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY129_00605	COG0167	dihydroorotate dehydrogenase activity
FY129_00620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY129_00640	COG1959	2 iron, 2 sulfur cluster binding
FY129_00645	COG1201	RNA secondary structure unwinding
FY129_00675	COG1960	acyl-CoA dehydrogenase activity
FY129_00680	COG0183	Belongs to the thiolase family
FY129_00685	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY129_00685	COG1024	Enoyl-CoA hydratase
FY129_00705	COG1320	monovalent cation:proton antiporter activity
FY129_00710	COG2212	antiporter activity
FY129_00715	COG1863	multisubunit Na H antiporter MnhE subunit
FY129_00720	COG0651	ATP synthesis coupled electron transport
FY129_00725	COG1006	Multisubunit Na H antiporter MnhC subunit
FY129_00730	COG2111	Na H antiporter
FY129_00730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY129_00740	COG0840	transmembrane signaling receptor activity
FY129_00750	COG0745	RESPONSE REGULATOR receiver
FY129_00755	COG0643	Histidine kinase
FY129_00755	COG2198	Histidine kinase
FY129_00760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY129_00765	COG2201	protein-glutamate methylesterase activity
FY129_00770	COG0745	RESPONSE REGULATOR receiver
FY129_00775	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY129_00785	COG1766	The M ring may be actively involved in energy transduction
FY129_00790	COG2771	luxR family
FY129_00800	COG0840	transmembrane signaling receptor activity
FY129_00800	COG2972	Histidine kinase
FY129_00805	COG0784	Response regulator, receiver
FY129_00805	COG2198	Histidine kinase
FY129_00805	COG2205	protein histidine kinase activity
FY129_00810	COG1970	mechanosensitive ion channel activity
FY129_00815	COG0436	Aminotransferase
FY129_00830	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY129_00835	COG0424	maF-like protein
FY129_00840	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY129_00850	COG5328	Belongs to the UPF0262 family
FY129_00855	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY129_00865	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY129_00885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY129_00895	COG1338	Plays a role in the flagellum-specific transport system
FY129_00905	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY129_00915	COG1706	bacterial-type flagellum-dependent cell motility
FY129_00920	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY129_00925	COG4786	Flagellar basal body rod
FY129_00930	COG1677	Flagellar hook-basal body complex protein FliE
FY129_00935	COG1558	bacterial-type flagellum-dependent cell motility
FY129_00940	COG1815	bacterial-type flagellum-dependent cell motility
FY129_00950	COG1157	protein secretion by the type III secretion system
FY129_00955	COG4786	Flagellar basal body rod
FY129_00965	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY129_00970	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY129_00975	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY129_00980	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY129_00985	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY129_01010	COG1360	Flagellar Motor Protein
FY129_01035	COG1749	Flagellar hook protein flgE
FY129_01055	COG5443	negative regulation of bacterial-type flagellum assembly
FY129_01060	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY129_01070	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY129_01110	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY129_01115	COG1609	Transcriptional regulator
FY129_01120	COG1653	transport
FY129_01125	COG1175	transmembrane transport
FY129_01130	COG0395	ABC-type sugar transport system, permease component
FY129_01135	COG0366	Alpha amylase catalytic
FY129_01140	COG3842	ATPase activity
FY129_01155	COG0129	dihydroxy-acid dehydratase activity
FY129_01160	COG0363	glucosamine-6-phosphate deaminase activity
FY129_01165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY129_01170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_01180	COG2081	HI0933 family
FY129_01200	COG2224	Isocitrate lyase
FY129_01215	COG3842	ATPase activity
FY129_01220	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_01225	COG1177	transmembrane transport
FY129_01230	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_01235	COG2205	protein histidine kinase activity
FY129_01245	COG0248	Ppx GppA phosphatase
FY129_01250	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY129_01255	COG0477	Major facilitator Superfamily
FY129_01285	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY129_01290	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY129_01300	COG0142	geranyltranstransferase activity
FY129_01325	COG0752	glycyl-tRNA synthetase alpha subunit
FY129_01335	COG1704	LemA family
FY129_01340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY129_01350	COG0751	glycine-tRNA ligase activity
FY129_01355	COG1683	Conserved Protein
FY129_01360	COG0840	transmembrane signaling receptor activity
FY129_01370	COG0151	Belongs to the GarS family
FY129_01375	COG2183	response to ionizing radiation
FY129_01380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY129_01405	COG0583	DNA-binding transcription factor activity
FY129_01425	COG0306	phosphate transporter
FY129_01435	COG0561	phosphatase activity
FY129_01440	COG0438	transferase activity, transferring glycosyl groups
FY129_01445	COG2186	Transcriptional regulator
FY129_01460	COG0583	DNA-binding transcription factor activity
FY129_01465	COG0277	FAD linked oxidase domain protein
FY129_01470	COG0277	FAD linked oxidase domain protein
FY129_01475	COG0247	lactate metabolic process
FY129_01485	COG1376	ErfK ybiS ycfS ynhG family protein
FY129_01490	COG2818	Glycosylase
FY129_01500	COG2855	membrane
FY129_01505	COG0583	DNA-binding transcription factor activity
FY129_01535	COG0124	histidyl-tRNA synthetase
FY129_01545	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY129_01550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY129_01555	COG2259	Doxx family
FY129_01565	COG0459	protein refolding
FY129_01570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY129_01580	COG0196	riboflavin kinase activity
FY129_01585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY129_01595	COG0590	tRNA wobble adenosine to inosine editing
FY129_01600	COG1187	pseudouridine synthase activity
FY129_01605	COG0742	ribosomal rna small subunit methyltransferase
FY129_01610	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY129_01620	COG0312	modulator of DNA gyrase
FY129_01625	COG0483	inositol monophosphate 1-phosphatase activity
FY129_01635	COG1519	Transferase
FY129_01645	COG1663	tetraacyldisaccharide 4'-kinase activity
FY129_01655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY129_01660	COG0745	RESPONSE REGULATOR receiver
FY129_01665	COG5001	Diguanylate cyclase
FY129_01665	COG3300	MHYT domain
FY129_01670	COG3386	PFAM SMP-30 Gluconolaconase
FY129_01675	COG0800	Aldolase
FY129_01680	COG3734	2-keto-3-deoxy-galactonokinase
FY129_01685	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_01690	COG1414	Transcriptional regulator
FY129_01695	COG2197	response regulator
FY129_01710	COG0598	Magnesium transport protein CorA
FY129_01715	COG3158	transport of potassium into the cell
FY129_01730	COG0356	it plays a direct role in the translocation of protons across the membrane
FY129_01740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY129_01745	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY129_01760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY129_01780	COG0009	L-threonylcarbamoyladenylate synthase
FY129_01790	COG4638	Rieske (2fe-2S)
FY129_01815	COG1960	acyl-CoA dehydrogenase activity
FY129_01830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY129_01840	COG0840	transmembrane signaling receptor activity
FY129_01850	COG1522	sequence-specific DNA binding
FY129_01875	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY129_01880	COG1741	Belongs to the pirin family
FY129_01885	COG1722	exodeoxyribonuclease VII activity
FY129_01890	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY129_01895	COG1268	BioY protein
FY129_01900	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY129_01905	COG1122	ATPase activity
FY129_01910	COG3214	Protein conserved in bacteria
FY129_01915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY129_01915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY129_01920	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY129_01940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY129_01955	COG0259	pyridoxamine-phosphate oxidase activity
FY129_01985	COG0312	modulator of DNA gyrase
FY129_02000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY129_02005	COG0109	protoheme IX farnesyltransferase activity
FY129_02010	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY129_02025	COG3346	SURF1 family
FY129_02030	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY129_02035	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY129_02040	COG0328	RNA-DNA hybrid ribonuclease activity
FY129_02050	COG0678	peroxiredoxin activity
FY129_02050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY129_02060	COG1678	Uncharacterized ACR, COG1678
FY129_02065	COG3237	CsbD-like
FY129_02075	COG3300	MHYT domain
FY129_02075	COG5001	Diguanylate cyclase
FY129_02080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY129_02085	COG0612	Peptidase, M16
FY129_02110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY129_02115	COG1802	Transcriptional regulator
FY129_02130	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY129_02135	COG3609	addiction module antidote protein, CC2985 family
FY129_02140	COG3668	Plasmid stabilization system
FY129_02150	COG1194	a g-specific adenine glycosylase
FY129_02165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY129_02170	COG1196	nuclear chromosome segregation
FY129_02175	COG2514	catechol 2,3-dioxygenase activity
FY129_02180	COG0574	Belongs to the PEP-utilizing enzyme family
FY129_02180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY129_02190	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FY129_02195	COG1823	symporter activity
FY129_02225	COG0579	oxidoreductase
FY129_02250	COG2895	sulfate adenylyltransferase (ATP) activity
FY129_02255	COG0175	sulfate reduction
FY129_02260	COG0175	sulfate reduction
FY129_02265	COG1959	2 iron, 2 sulfur cluster binding
FY129_02270	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY129_02280	COG4208	sulfate ABC transporter
FY129_02285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY129_02295	COG2199	diguanylate cyclase activity
FY129_02295	COG2200	EAL domain
FY129_02295	COG2203	Gaf domain
FY129_02305	COG1309	transcriptional regulator
FY129_02310	COG1012	belongs to the aldehyde dehydrogenase family
FY129_02315	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY129_02345	COG0625	glutathione transferase activity
FY129_02355	COG0477	Major facilitator Superfamily
FY129_02365	COG3657	addiction module killer protein
FY129_02375	COG1793	dna ligase
FY129_02395	COG1376	ErfK ybiS ycfS ynhG family protein
FY129_02400	COG1376	ErfK ybiS ycfS ynhG family protein
FY129_02405	COG1846	Transcriptional regulator
FY129_02410	COG1764	response to oxidative stress
FY129_02425	COG0488	(ABC) transporter
FY129_02460	COG4221	oxidoreductase activity
FY129_02475	COG0433	COG0433 Predicted ATPase
FY129_02485	COG1733	regulation of RNA biosynthetic process
FY129_02490	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY129_02505	COG0656	L-ascorbic acid biosynthetic process
FY129_02510	COG3781	membrane
FY129_02525	COG4106	trans-aconitate 2-methyltransferase activity
FY129_02530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY129_02535	COG0840	transmembrane signaling receptor activity
FY129_02540	COG0583	DNA-binding transcription factor activity
FY129_02555	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY129_02575	COG3909	cytochrome
FY129_02580	COG2010	Cytochrome c
FY129_02610	COG0789	Transcriptional regulator
FY129_02635	COG4175	Glycine betaine
FY129_02635	COG0517	IMP dehydrogenase activity
FY129_02640	COG4176	ABC-type proline glycine betaine transport system permease component
FY129_02660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_02670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY129_02670	COG2169	Transcriptional regulator
FY129_02680	COG2514	catechol 2,3-dioxygenase activity
FY129_02695	COG1272	protein, Hemolysin III
FY129_02705	COG1280	lysine exporter protein (LysE YggA)
FY129_02710	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY129_02715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY129_02715	COG2111	Na H antiporter
FY129_02720	COG2111	Na H antiporter
FY129_02725	COG1006	Multisubunit Na H antiporter MnhC subunit
FY129_02730	COG0651	ATP synthesis coupled electron transport
FY129_02735	COG1863	multisubunit Na H antiporter MnhE subunit
FY129_02740	COG2212	antiporter activity
FY129_02745	COG1320	monovalent cation:proton antiporter activity
FY129_02750	COG4957	zinc ion binding
FY129_02765	COG2166	iron-sulfur cluster assembly
FY129_02775	COG2205	protein histidine kinase activity
FY129_02815	COG0583	DNA-binding transcription factor activity
FY129_02820	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY129_02825	COG2983	Belongs to the UPF0260 family
FY129_02870	COG2814	Major facilitator Superfamily
FY129_02875	COG1621	beta-fructofuranosidase activity
FY129_02880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY129_02930	COG4695	Portal protein
FY129_03035	COG4235	cytochrome complex assembly
FY129_03040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY129_03045	COG1138	Cytochrome C-type biogenesis protein
FY129_03050	COG3088	subunit of a heme lyase
FY129_03055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY129_03060	COG0745	RESPONSE REGULATOR receiver
FY129_03065	COG2205	protein histidine kinase activity
FY129_03070	COG3011	Protein conserved in bacteria
FY129_03075	COG3713	MltA-interacting MipA family protein
FY129_03080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY129_03085	COG2202	Pas domain
FY129_03085	COG2205	protein histidine kinase activity
FY129_03095	COG0308	aminopeptidase N
FY129_03100	COG0697	spore germination
FY129_03115	COG0443	Heat shock 70 kDa protein
FY129_03150	COG0604	alcohol dehydrogenase
FY129_03155	COG1733	regulation of RNA biosynthetic process
FY129_03160	COG1968	undecaprenyl-diphosphatase activity
FY129_03165	COG2239	Acts as a magnesium transporter
FY129_03170	COG2814	Major facilitator Superfamily
FY129_03195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY129_03220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY129_03380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FY129_03385	COG0741	lytic transglycosylase activity
FY129_03390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_03395	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY129_03400	COG0840	transmembrane signaling receptor activity
FY129_03410	COG1758	RNA polymerase activity
FY129_03430	COG0736	holo-[acyl-carrier-protein] synthase activity
FY129_03435	COG0681	Belongs to the peptidase S26 family
FY129_03440	COG0571	ribonuclease III activity
FY129_03445	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY129_03455	COG0784	Response regulator, receiver
FY129_03460	COG1381	Involved in DNA repair and RecF pathway recombination
FY129_03470	COG2226	methyltransferase
FY129_03480	COG1418	mRNA catabolic process
FY129_03490	COG0346	lactoylglutathione lyase activity
FY129_03505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_03510	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY129_03515	COG0668	transmembrane transport
FY129_03525	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY129_03555	COG1742	UPF0060 membrane protein
FY129_03570	COG1183	phosphatidylcholine synthase activity
FY129_03575	COG0688	phosphatidylethanolamine metabolic process
FY129_03580	COG5265	(ABC) transporter
FY129_03620	COG2852	Protein conserved in bacteria
FY129_03625	COG0215	cysteine-tRNA ligase activity
FY129_03630	COG4221	oxidoreductase activity
FY129_03635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY129_03640	COG1286	toxin biosynthetic process
FY129_03660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY129_03670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY129_03680	COG0305	Participates in initiation and elongation during chromosome replication
FY129_03700	COG0359	binds to the 23S rRNA
FY129_03710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY129_03715	COG0360	Binds together with S18 to 16S ribosomal RNA
FY129_03725	COG0667	Aldo Keto reductase
FY129_03730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY129_03740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY129_03745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY129_03755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY129_03760	COG1561	YicC-like family, N-terminal region
FY129_03765	COG0194	GDP metabolic process
FY129_03780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY129_03785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY129_03795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY129_03810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY129_03830	COG2203	Gaf domain
FY129_03830	COG3706	GGDEF domain
FY129_03830	COG4251	negative regulation of phosphorylation
FY129_03830	COG5001	Diguanylate cyclase
FY129_03835	COG5001	Diguanylate cyclase
FY129_03835	COG3300	MHYT domain
FY129_03840	COG4191	Histidine kinase
FY129_03845	COG4566	intracellular signal transduction
FY129_03855	COG0488	(ABC) transporter
FY129_03860	COG3706	GGDEF domain
FY129_03870	COG0105	UTP biosynthetic process
FY129_03890	COG0314	molybdopterin synthase activity
FY129_03900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY129_03905	COG0322	excinuclease ABC activity
FY129_03910	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_03925	COG3719	Belongs to the RNase T2 family
FY129_03935	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY129_03940	COG0243	molybdopterin cofactor binding
FY129_03965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY129_03970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY129_03975	COG2226	methyltransferase
FY129_03980	COG0628	permease
FY129_03990	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY129_03995	COG0248	Ppx GppA phosphatase
FY129_04020	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY129_04030	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY129_04035	COG0477	Major facilitator Superfamily
FY129_04040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY129_04050	COG0840	transmembrane signaling receptor activity
FY129_04055	COG0659	secondary active sulfate transmembrane transporter activity
FY129_04065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY129_04070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY129_04080	COG0113	porphobilinogen synthase activity
FY129_04100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY129_04105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY129_04110	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY129_04110	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY129_04120	COG1280	lysine exporter protein (LysE YggA)
FY129_04125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY129_04130	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY129_04135	COG2814	Major facilitator Superfamily
FY129_04140	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY129_04160	COG0416	fatty acid biosynthetic process
FY129_04165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY129_04170	COG0776	regulation of translation
FY129_04205	COG0601	transmembrane transport
FY129_04210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_04215	COG0444	Belongs to the ABC transporter superfamily
FY129_04225	COG0747	negative chemotaxis
FY129_04235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY129_04240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY129_04255	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY129_04260	COG0583	DNA-binding transcription factor activity
FY129_04265	COG0737	Belongs to the 5'-nucleotidase family
FY129_04285	COG2897	thiosulfate sulfurtransferase activity
FY129_04300	COG0415	Belongs to the DNA photolyase family
FY129_04310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY129_04425	COG3750	Belongs to the UPF0335 family
FY129_04470	COG4695	Portal protein
FY129_04645	COG3932	Exopolysaccharide synthesis, ExoD
FY129_04650	COG1238	metal cluster binding
FY129_04725	COG1612	heme a metabolic process
FY129_04735	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY129_04740	COG0010	Belongs to the arginase family
FY129_04745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY129_04750	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY129_04760	COG1832	CoA-binding protein
FY129_04785	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_04790	COG2124	cytochrome p450
FY129_04795	COG2199	diguanylate cyclase activity
FY129_04800	COG0740	serine-type endopeptidase activity
FY129_04805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY129_04810	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY129_04820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY129_04840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY129_04845	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY129_04850	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY129_04860	COG0649	NAD binding
FY129_04870	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY129_04875	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY129_04885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY129_04890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY129_04900	COG0713	ATP synthesis coupled electron transport
FY129_04915	COG1007	ATP synthesis coupled electron transport
FY129_04920	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY129_04920	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY129_04935	COG0442	prolyl-tRNA aminoacylation
FY129_04945	COG1136	(ABC) transporter
FY129_04960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY129_04980	COG0784	Response regulator, receiver
FY129_04990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY129_04995	COG0477	Major facilitator Superfamily
FY129_05010	COG0557	exoribonuclease II activity
FY129_05015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY129_05025	COG0758	DNA mediated transformation
FY129_05030	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY129_05040	COG0540	Belongs to the ATCase OTCase family
FY129_05055	COG1960	acyl-CoA dehydrogenase activity
FY129_05060	COG0456	acetyltransferase
FY129_05080	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY129_05085	COG2824	Alkylphosphonate utilization operon protein PhnA
FY129_05090	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY129_05095	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY129_05100	COG0154	amidase activity
FY129_05105	COG0456	acetyltransferase
FY129_05110	COG3811	Belongs to the UPF0386 family
FY129_05125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY129_05135	COG0456	acetyltransferase
FY129_05155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY129_05160	COG0439	Biotin carboxylase
FY129_05165	COG0511	ligase activity, forming carbon-carbon bonds
FY129_05170	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY129_05180	COG0436	Aminotransferase
FY129_05200	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_05205	COG1530	ribonuclease E activity
FY129_05215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY129_05235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY129_05240	COG0384	phenazine biosynthesis protein PhzF
FY129_05260	COG0633	Ferredoxin
FY129_05275	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY129_05280	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY129_05290	COG3768	UPF0283 membrane protein
FY129_05295	COG3106	COG3106 Predicted ATPase
FY129_05325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY129_05360	COG0537	adenosine 5'-monophosphoramidase activity
FY129_05385	COG0052	Belongs to the universal ribosomal protein uS2 family
FY129_05390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY129_05395	COG0528	UMP kinase activity
FY129_05400	COG0233	cytoplasmic translational termination
FY129_05405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY129_05415	COG0750	zinc metalloprotease
FY129_05420	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY129_05425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY129_05430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY129_05435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY129_05440	COG3494	Protein of unknown function (DUF1009)
FY129_05445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY129_05450	COG2186	Transcriptional regulator
FY129_05460	COG0765	amino acid transport
FY129_05465	COG0765	amino acid transport
FY129_05475	COG0372	Belongs to the citrate synthase family
FY129_05490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY129_05500	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY129_05505	COG0148	phosphopyruvate hydratase activity
FY129_05515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY129_05520	COG0022	dehydrogenase e1 component
FY129_05520	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY129_05525	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY129_05535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY129_05545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY129_05550	COG0697	spore germination
FY129_05565	COG2867	negative regulation of translational initiation
FY129_05570	COG1546	Belongs to the CinA family
FY129_05575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY129_05575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY129_05585	COG3852	Histidine kinase
FY129_05590	COG2204	response regulator
FY129_05595	COG5000	phosphorelay sensor kinase activity
FY129_05600	COG2204	response regulator
FY129_05605	COG0569	domain protein
FY129_05610	COG1923	regulation of RNA biosynthetic process
FY129_05615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY129_05620	COG3956	TIGRFAM MazG family protein
FY129_05630	COG1648	precorrin-2 dehydrogenase activity
FY129_05630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY129_05670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY129_05670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY129_05675	COG0509	glycine decarboxylation via glycine cleavage system
FY129_05680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY129_05705	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY129_05710	COG0564	pseudouridine synthase activity
FY129_05730	COG0251	oxidation-reduction process
FY129_05735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY129_05745	COG1671	Belongs to the UPF0178 family
FY129_05760	COG0450	alkyl hydroperoxide reductase
FY129_05770	COG0625	glutathione transferase activity
FY129_05780	COG2801	Transposase and inactivated derivatives
FY129_05785	COG0431	NADPH-dependent FMN reductase
FY129_05795	COG0798	PFAM Bile acid sodium symporter
FY129_05800	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY129_05815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY129_05815	COG0321	lipoyl(octanoyl) transferase activity
FY129_05820	COG0084	hydrolase, TatD family'
FY129_05825	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY129_05835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY129_05885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY129_05890	COG2095	MarC family integral membrane protein
FY129_05895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY129_05895	COG0517	IMP dehydrogenase activity
FY129_05895	COG0617	tRNA 3'-terminal CCA addition
FY129_05905	COG0629	single-stranded DNA binding
FY129_05910	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY129_05920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY129_05940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY129_05945	COG1121	(ABC) transporter
FY129_05965	COG0667	Aldo Keto reductase
FY129_05975	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY129_06060	COG2239	Acts as a magnesium transporter
FY129_06065	COG0243	molybdopterin cofactor binding
FY129_06075	COG0242	peptide deformylase activity
FY129_06085	COG2202	Pas domain
FY129_06085	COG2205	protein histidine kinase activity
FY129_06095	COG0321	lipoyl(octanoyl) transferase activity
FY129_06100	COG1064	alcohol dehydrogenase
FY129_06130	COG1862	Preprotein translocase
FY129_06150	COG2124	cytochrome p450
FY129_06165	COG2267	carboxylic ester hydrolase activity
FY129_06180	COG0626	cystathionine gamma-synthase activity
FY129_06185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_06190	COG4597	amino acid ABC transporter
FY129_06195	COG0765	amino acid transport
FY129_06200	COG1126	abc transporter atp-binding protein
FY129_06215	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY129_06230	COG0436	Aminotransferase
FY129_06260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY129_06270	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY129_06275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY129_06280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY129_06295	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY129_06300	COG1489	DNA binding
FY129_06305	COG0024	Methionine aminopeptidase
FY129_06310	COG2003	Belongs to the UPF0758 family
FY129_06325	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY129_06350	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY129_06355	COG0546	phosphoglycolate phosphatase activity
FY129_06365	COG0114	fumarate hydratase activity
FY129_06375	COG0504	CTP synthase activity
FY129_06385	COG0149	triose-phosphate isomerase activity
FY129_06395	COG0187	DNA topoisomerase II activity
FY129_06405	COG0740	serine-type endopeptidase activity
FY129_06415	COG0640	Transcriptional regulator
FY129_06420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY129_06425	COG0745	RESPONSE REGULATOR receiver
FY129_06445	COG3264	Mechanosensitive ion channel
FY129_06445	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY129_06505	COG1127	ABC transporter
FY129_06510	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY129_06515	COG4948	Mandelate Racemase Muconate Lactonizing
FY129_06525	COG0281	malic enzyme
FY129_06525	COG0280	phosphate acetyltransferase
FY129_06535	COG0778	Nitroreductase
FY129_06540	COG0823	Involved in the tonB-independent uptake of proteins
FY129_06555	COG1368	sulfuric ester hydrolase activity
FY129_06575	COG3265	gluconokinase activity
FY129_06580	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY129_06600	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY129_06620	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY129_06635	COG0318	PFAM AMP-dependent synthetase and ligase
FY129_06645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY129_06645	COG0512	Glutamine amidotransferase of anthranilate synthase
FY129_06650	COG0343	queuine tRNA-ribosyltransferase activity
FY129_06655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY129_06670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY129_06685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY129_06690	COG0134	indole-3-glycerol-phosphate synthase activity
FY129_06695	COG0315	cyclic pyranopterin monophosphate synthase activity
FY129_06700	COG0303	'Molybdopterin
FY129_06705	COG3706	GGDEF domain
FY129_06715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY129_06715	COG0475	glutathione-regulated potassium exporter activity
FY129_06725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY129_06735	COG2814	Major facilitator Superfamily
FY129_06740	COG0746	molybdenum cofactor guanylyltransferase activity
FY129_06745	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY129_06750	COG0739	heme binding
FY129_06755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY129_06760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY129_06765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY129_06770	COG0805	protein transport
FY129_06775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY129_06780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY129_06785	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY129_06790	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY129_06795	COG1472	Belongs to the glycosyl hydrolase 3 family
FY129_06805	COG0018	arginyl-trna synthetase
FY129_06810	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY129_06835	COG0525	valine-tRNA ligase activity
FY129_06845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY129_06875	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY129_06880	COG1058	Belongs to the CinA family
FY129_06880	COG1546	Belongs to the CinA family
FY129_06885	COG0589	response to stress
FY129_06890	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY129_06895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY129_06905	COG0640	Transcriptional regulator
FY129_06910	COG1914	H( )-stimulated, divalent metal cation uptake system
FY129_06920	COG1132	(ABC) transporter
FY129_06925	COG0628	permease
FY129_06960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY129_06970	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY129_06980	COG0302	gtp cyclohydrolase
FY129_06985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY129_06990	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY129_07000	COG0516	GMP reductase activity
FY129_07000	COG0517	IMP dehydrogenase activity
FY129_07035	COG1760	l-serine dehydratase
FY129_07075	COG0583	DNA-binding transcription factor activity
FY129_07090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY129_07090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY129_07100	COG0347	Belongs to the P(II) protein family
FY129_07105	COG0174	glutamine synthetase
FY129_07135	COG0697	spore germination
FY129_07145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY129_07155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY129_07185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY129_07190	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY129_07195	COG2186	Transcriptional regulator
FY129_07205	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY129_07210	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY129_07215	COG3845	ABC transporter
FY129_07220	COG1183	phosphatidylcholine synthase activity
FY129_07225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY129_07230	COG0679	Auxin Efflux Carrier
FY129_07235	COG0785	Cytochrome C biogenesis protein
FY129_07255	COG1278	Cold shock
FY129_07310	COG1136	(ABC) transporter
FY129_07310	COG0577	efflux transmembrane transporter activity
FY129_07315	COG1136	(ABC) transporter
FY129_07315	COG0577	efflux transmembrane transporter activity
FY129_07340	COG2151	metal-sulfur cluster biosynthetic enzyme
FY129_07345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY129_07350	COG0719	Fe-S assembly protein
FY129_07355	COG0396	ATPase activity
FY129_07360	COG0719	Fe-S assembly protein
FY129_07365	COG1104	cysteine desulfurase activity
FY129_07370	COG2945	thiolester hydrolase activity
FY129_07375	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY129_07380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY129_07390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY129_07395	COG2833	Protein of unknown function (DUF455)
FY129_07400	COG0739	heme binding
FY129_07405	COG0513	Belongs to the DEAD box helicase family
FY129_07430	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY129_07440	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY129_07445	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY129_07450	COG0047	phosphoribosylformylglycinamidine synthase activity
FY129_07465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY129_07470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY129_07495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY129_07500	COG2814	Major facilitator Superfamily
FY129_07505	COG0483	inositol monophosphate 1-phosphatase activity
FY129_07510	COG0483	inositol monophosphate 1-phosphatase activity
FY129_07515	COG0037	tRNA processing
FY129_07520	COG2066	Belongs to the glutaminase family
FY129_07525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY129_07530	COG0861	Integral membrane protein TerC family
FY129_07545	COG1280	lysine exporter protein (LysE YggA)
FY129_07555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY129_07560	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY129_07570	COG0538	isocitrate dehydrogenase activity
FY129_07580	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY129_07585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY129_07590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_07595	COG2313	pseudouridylate synthase activity
FY129_07605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_07620	COG5425	PFAM Usg family protein
FY129_07630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY129_07635	COG1522	sequence-specific DNA binding
FY129_07640	COG1573	uracil-dna glycosylase
FY129_07650	COG2202	Pas domain
FY129_07650	COG2205	protein histidine kinase activity
FY129_07655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY129_07660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY129_07665	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY129_07680	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY129_07685	COG0842	Transport permease protein
FY129_07690	COG1131	(ABC) transporter
FY129_07695	COG0730	response to heat
FY129_07695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY129_07715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY129_07720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY129_07740	COG0129	dihydroxy-acid dehydratase activity
FY129_07745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY129_07750	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY129_07760	COG3739	integral membrane protein
FY129_07765	COG0203	ribosomal protein L17
FY129_07770	COG0202	RNA polymerase activity
FY129_07775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY129_07780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY129_07785	COG0563	adenylate kinase activity
FY129_07790	COG0201	protein transport
FY129_07795	COG0200	Binds to the 23S rRNA
FY129_07800	COG1841	ribosomal large subunit assembly
FY129_07805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY129_07810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY129_07815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY129_07820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY129_07825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY129_07830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY129_07835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY129_07840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY129_07845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY129_07850	COG0255	Belongs to the universal ribosomal protein uL29 family
FY129_07855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY129_07860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY129_07865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY129_07870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY129_07875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY129_07880	COG0089	rRNA binding
FY129_07885	COG0088	Forms part of the polypeptide exit tunnel
FY129_07890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY129_07895	COG0051	transcription antitermination factor activity, RNA binding
FY129_07900	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY129_07905	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY129_07910	COG0049	tRNA binding
FY129_07915	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY129_07935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY129_07940	COG0085	RNA polymerase activity
FY129_07945	COG0222	ribosome binding
FY129_07950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY129_07955	COG0081	regulation of translation
FY129_07960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY129_07970	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY129_07980	COG1086	Polysaccharide biosynthesis protein
FY129_07985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY129_07990	COG0861	Integral membrane protein TerC family
FY129_08015	COG1132	(ABC) transporter
FY129_08020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY129_08040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY129_08075	COG2205	protein histidine kinase activity
FY129_08075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_08075	COG2198	Histidine kinase
FY129_08075	COG0784	Response regulator, receiver
FY129_08080	COG0784	Response regulator, receiver
FY129_08085	COG2202	Pas domain
FY129_08085	COG3920	Histidine kinase
FY129_08090	COG0784	Response regulator, receiver
FY129_08095	COG4251	negative regulation of phosphorylation
FY129_08110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY129_08115	COG1607	acyl-coa hydrolase
FY129_08135	COG2910	NAD(P)H-binding
FY129_08140	COG1733	regulation of RNA biosynthetic process
FY129_08155	COG0556	nucleotide-excision repair
FY129_08165	COG2382	esterase
FY129_08185	COG0484	heat shock protein binding
FY129_08205	COG3706	GGDEF domain
FY129_08225	COG1840	ABC-type Fe3 transport system, periplasmic component
FY129_08230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY129_08245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY129_08255	COG2207	Transcriptional regulator
FY129_08260	COG1064	alcohol dehydrogenase
FY129_08265	COG1252	NADH dehydrogenase
FY129_08270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY129_08275	COG2197	response regulator
FY129_08280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY129_08315	COG0656	L-ascorbic acid biosynthetic process
FY129_08330	COG0440	acetolactate synthase activity
FY129_08335	COG0028	Belongs to the TPP enzyme family
FY129_08345	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY129_08350	COG0560	Phosphoserine phosphatase
FY129_08350	COG3830	Belongs to the UPF0237 family
FY129_08370	COG0330	HflC and HflK could
FY129_08375	COG0330	HflC and HflK could
FY129_08385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY129_08420	COG0277	FAD linked oxidase domain protein
FY129_08425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY129_08465	COG1335	isochorismatase
FY129_08490	COG2264	protein methyltransferase activity
FY129_08495	COG1999	signal sequence binding
FY129_08505	COG0835	chemotaxis
FY129_08515	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY129_08520	COG0583	DNA-binding transcription factor activity
FY129_08530	COG1247	-acetyltransferase
FY129_08540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY129_08545	COG0497	DNA recombination
FY129_08550	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY129_08560	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY129_08565	COG0849	cell division
FY129_08570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY129_08575	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY129_08580	COG0477	Major facilitator Superfamily
FY129_08590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY129_08595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY129_08600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY129_08610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY129_08615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY129_08625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY129_08640	COG0275	rRNA processing
FY129_08645	COG2001	Belongs to the MraZ family
FY129_08670	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY129_08700	COG4106	trans-aconitate 2-methyltransferase activity
FY129_08720	COG2226	methyltransferase
FY129_08730	COG2267	carboxylic ester hydrolase activity
FY129_08735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY129_08750	COG0251	oxidation-reduction process
FY129_08765	COG1376	ErfK ybiS ycfS ynhG family protein
FY129_08770	COG2814	Major facilitator Superfamily
FY129_08800	COG1012	belongs to the aldehyde dehydrogenase family
FY129_08805	COG0174	glutamine synthetase
FY129_08810	COG0531	amino acid
FY129_08820	COG1737	Transcriptional regulator
FY129_08825	COG2182	Extracellular solute-binding protein
FY129_08840	COG3842	ATPase activity
FY129_08900	COG2968	Membrane
FY129_08910	COG0432	Pfam Uncharacterised protein family UPF0047
FY129_08925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY129_08930	COG0358	DNA primase activity
FY129_08955	COG0505	Belongs to the CarA family
FY129_08960	COG0534	Mate efflux family protein
FY129_08975	COG2321	neutral zinc metallopeptidase
FY129_08990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY129_09000	COG3706	GGDEF domain
FY129_09015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY129_09025	COG1522	sequence-specific DNA binding
FY129_09030	COG0492	ferredoxin-NADP+ reductase activity
FY129_09035	COG0583	DNA-binding transcription factor activity
FY129_09045	COG1902	pentaerythritol trinitrate reductase activity
FY129_09070	COG0387	Pfam Sodium calcium exchanger
FY129_09075	COG0436	Aminotransferase
FY129_09080	COG2199	diguanylate cyclase activity
FY129_09080	COG2200	EAL domain
FY129_09095	COG1278	Cold shock
FY129_09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY129_09110	COG1846	Transcriptional regulator
FY129_09115	COG0745	RESPONSE REGULATOR receiver
FY129_09125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY129_09145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY129_09155	COG1496	oxidoreductase activity
FY129_09170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY129_09180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY129_09195	COG0840	transmembrane signaling receptor activity
FY129_09200	COG1012	belongs to the aldehyde dehydrogenase family
FY129_09205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY129_09210	COG5001	Diguanylate cyclase
FY129_09210	COG3300	MHYT domain
FY129_09215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY129_09220	COG5001	Diguanylate cyclase
FY129_09230	COG0193	aminoacyl-tRNA hydrolase activity
FY129_09240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY129_09265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY129_09275	COG2857	Cytochrome c1
FY129_09275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY129_09295	COG1132	(ABC) transporter
FY129_09300	COG1132	(ABC) transporter
FY129_09310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY129_09325	COG0408	coproporphyrinogen oxidase activity
FY129_09340	COG0617	tRNA 3'-terminal CCA addition
FY129_09355	COG0714	Associated with various cellular activities
FY129_09375	COG0454	-acetyltransferase
FY129_09390	COG0477	Major facilitator Superfamily
FY129_09400	COG0435	Glutathione S-transferase
FY129_09405	COG0494	nUDIX hydrolase
FY129_09415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY129_09420	COG3135	benzoate transporter
FY129_09445	COG0740	serine-type endopeptidase activity
FY129_09460	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY129_09465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY129_09490	COG4175	Glycine betaine
FY129_09510	COG1435	thymidine kinase activity
FY129_09535	COG1629	transport
FY129_09535	COG4771	TonB-dependent receptor
FY129_09545	COG0512	Glutamine amidotransferase of anthranilate synthase
FY129_09545	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY129_09560	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY129_09570	COG0366	Alpha amylase catalytic
FY129_09575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_09595	COG1160	GTP binding
FY129_09615	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY129_09625	COG0024	Methionine aminopeptidase
FY129_09635	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_09645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY129_09655	COG0583	DNA-binding transcription factor activity
FY129_09670	COG0402	S-adenosylhomocysteine deaminase activity
FY129_09680	COG1304	FMN binding
FY129_09690	COG1309	transcriptional regulator
FY129_09695	COG1686	Belongs to the peptidase S11 family
FY129_09705	COG2351	hydroxyisourate hydrolase activity
FY129_09710	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY129_09735	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY129_09745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_09745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY129_09755	COG0513	Belongs to the DEAD box helicase family
FY129_09765	COG2259	Doxx family
FY129_09770	COG1376	ErfK ybiS ycfS ynhG family protein
FY129_09780	COG2308	Evidence 4 Homologs of previously reported genes of
FY129_09790	COG1305	Transglutaminase-like
FY129_09815	COG4214	carbohydrate transport
FY129_09825	COG4213	ABC transporter substrate-binding protein
FY129_09860	COG2972	Histidine kinase
FY129_09860	COG0840	transmembrane signaling receptor activity
FY129_09875	COG0646	methionine synthase
FY129_09875	COG1410	methionine synthase
FY129_09920	COG1215	transferase activity, transferring glycosyl groups
FY129_09950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY129_09965	COG2346	COG2346, Truncated hemoglobins
FY129_09985	COG1309	transcriptional regulator
FY129_10000	COG0494	nUDIX hydrolase
FY129_10010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_10015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_10045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY129_10050	COG0830	nickel cation binding
FY129_10055	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY129_10070	COG0804	urea catabolic process
FY129_10075	COG1442	glycosyl transferase family 8
FY129_10080	COG3755	Protein conserved in bacteria
FY129_10090	COG0832	Belongs to the urease beta subunit family
FY129_10095	COG3813	Protein conserved in bacteria
FY129_10100	COG0831	urea catabolic process
FY129_10105	COG0829	nickel cation binding
FY129_10130	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY129_10145	COG0174	glutamine synthetase
FY129_10150	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_10155	COG2198	Histidine kinase
FY129_10155	COG0784	Response regulator, receiver
FY129_10155	COG5002	protein histidine kinase activity
FY129_10170	COG0726	polysaccharide deacetylase
FY129_10205	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY129_10280	COG0564	pseudouridine synthase activity
FY129_10290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY129_10300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY129_10325	COG0346	lactoylglutathione lyase activity
FY129_10335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY129_10345	COG2832	Protein of unknown function (DUF454)
FY129_10350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY129_10355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_10360	COG4558	Periplasmic binding protein
FY129_10370	COG3721	Heme iron utilization protein
FY129_10385	COG3655	Transcriptional regulator
FY129_10400	COG3657	addiction module killer protein
FY129_10410	COG2205	protein histidine kinase activity
FY129_10450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_10455	COG4605	iron ion homeostasis
FY129_10460	COG4604	ABC transporter, ATP-binding protein
FY129_10465	COG0783	Belongs to the Dps family
FY129_10480	COG2972	Histidine kinase
FY129_10480	COG0840	transmembrane signaling receptor activity
FY129_10485	COG0656	L-ascorbic acid biosynthetic process
FY129_10490	COG2814	Major facilitator Superfamily
FY129_10500	COG0583	DNA-binding transcription factor activity
FY129_10505	COG0657	acetylesterase activity
FY129_10510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_10530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY129_10535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY129_10540	COG0288	reversible hydration of carbon dioxide
FY129_10550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY129_10570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY129_10575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY129_10580	COG0778	Nitroreductase
FY129_10585	COG2267	carboxylic ester hydrolase activity
FY129_10590	COG0251	oxidation-reduction process
FY129_10595	COG1335	isochorismatase
FY129_10600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_10610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_10625	COG1175	transmembrane transport
FY129_10630	COG0395	ABC-type sugar transport system, permease component
FY129_10635	COG3842	ATPase activity
FY129_10640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_10650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY129_10665	COG4608	Belongs to the ABC transporter superfamily
FY129_10670	COG0444	Belongs to the ABC transporter superfamily
FY129_10675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_10680	COG0601	transmembrane transport
FY129_10735	COG2159	amidohydrolase
FY129_10740	COG1960	acyl-CoA dehydrogenase activity
FY129_10770	COG0745	RESPONSE REGULATOR receiver
FY129_10780	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY129_10780	COG1902	pentaerythritol trinitrate reductase activity
FY129_10785	COG3842	ATPase activity
FY129_10795	COG1840	ABC-type Fe3 transport system, periplasmic component
FY129_10800	COG1840	ABC-type Fe3 transport system, periplasmic component
FY129_10805	COG0745	RESPONSE REGULATOR receiver
FY129_10815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY129_10820	COG0583	DNA-binding transcription factor activity
FY129_10825	COG1278	Cold shock
FY129_10845	COG0210	DNA helicase
FY129_10875	COG0753	catalase activity
FY129_10890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_10905	COG0668	transmembrane transport
FY129_10950	COG0668	transmembrane transport
FY129_10960	COG1012	belongs to the aldehyde dehydrogenase family
FY129_11035	COG2860	membrane
FY129_11050	COG1216	Glycosyl transferase, family 2
FY129_11050	COG0463	Glycosyl transferase, family 2
FY129_11090	COG2204	response regulator
FY129_11095	COG2200	EAL domain
FY129_11095	COG2199	diguanylate cyclase activity
FY129_11110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY129_11140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY129_11145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY129_11210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY129_11215	COG1309	transcriptional regulator
FY129_11220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_11225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY129_11235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY129_11240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY129_11260	COG0583	DNA-binding transcription factor activity
FY129_11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_11270	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY129_11275	COG4149	molybdate abc transporter
FY129_11280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY129_11295	COG2022	thiamine diphosphate biosynthetic process
FY129_11310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY129_11320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY129_11330	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY129_11350	COG1132	(ABC) transporter
FY129_11355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY129_11400	COG4166	transmembrane transport
FY129_11405	COG0601	transmembrane transport
FY129_11410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_11420	COG0438	transferase activity, transferring glycosyl groups
FY129_11425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY129_11430	COG3142	Participates in the control of copper homeostasis
FY129_11435	COG2814	Major facilitator Superfamily
FY129_11450	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_11455	COG1737	Transcriptional regulator
FY129_11465	COG3842	ATPase activity
FY129_11475	COG0395	ABC-type sugar transport system, permease component
FY129_11490	COG2188	Transcriptional regulator
FY129_11495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY129_11500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY129_11505	COG1940	carbohydrate kinase activity
FY129_11515	COG0671	phosphoesterase, PA-phosphatase related
FY129_11520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY129_11525	COG0156	8-amino-7-oxononanoate synthase activity
FY129_11535	COG0729	surface antigen
FY129_11545	COG0835	chemotaxis
FY129_11555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY129_11560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY129_11565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY129_11570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY129_11575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY129_11580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY129_11595	COG4974	Belongs to the 'phage' integrase family
FY129_11620	COG1280	lysine exporter protein (LysE YggA)
FY129_11630	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY129_11635	COG0567	Dehydrogenase, E1 component
FY129_11640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY129_11645	COG0045	succinate-CoA ligase (ADP-forming) activity
FY129_11650	COG0039	L-malate dehydrogenase activity
FY129_11655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY129_11690	COG2264	protein methyltransferase activity
FY129_11705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY129_11710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY129_11715	COG0181	hydroxymethylbilane synthase activity
FY129_11755	COG1872	DUF167
FY129_11760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY129_11770	COG1217	gtp-binding protein TYPA
FY129_11775	COG0339	signal peptide processing
FY129_11780	COG1846	Transcriptional regulator
FY129_11790	COG0137	argininosuccinate synthase activity
FY129_11800	COG1280	lysine exporter protein (LysE YggA)
FY129_11805	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY129_11810	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY129_11820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY129_11835	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY129_11840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY129_11845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY129_11855	COG4181	ATPase activity
FY129_11865	COG0670	Belongs to the BI1 family
FY129_11880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY129_11885	COG4133	protoheme IX ABC transporter activity
FY129_11890	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY129_11895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY129_11920	COG2917	probably involved in intracellular septation
FY129_11925	COG0552	protein localization to endoplasmic reticulum
FY129_11930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY129_11935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY129_11950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY129_11955	COG0287	Prephenate dehydrogenase
FY129_11955	COG1605	Chorismate mutase
FY129_11960	COG0228	four-way junction DNA binding
FY129_11965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY129_11970	COG0336	Belongs to the RNA methyltransferase TrmD family
FY129_11980	COG0335	large ribosomal subunit rRNA binding
FY129_11985	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY129_11990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_12005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY129_12025	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY129_12045	COG0488	(ABC) transporter
FY129_12055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY129_12065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY129_12070	COG0142	geranyltranstransferase activity
FY129_12075	COG2885	chlorophyll binding
FY129_12080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY129_12085	COG2223	nitrite transmembrane transporter activity
FY129_12090	COG1349	DNA-binding transcription factor activity
FY129_12095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY129_12100	COG2197	response regulator
FY129_12105	COG1132	(ABC) transporter
FY129_12110	COG3459	Glycosyltransferase 36 associated
FY129_12115	COG1473	amidohydrolase
FY129_12120	COG0579	oxidoreductase
FY129_12130	COG0129	dihydroxy-acid dehydratase activity
FY129_12135	COG2084	Dehydrogenase
FY129_12140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY129_12145	COG0277	FAD linked oxidase domain protein
FY129_12150	COG2186	Transcriptional regulator
FY129_12160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY129_12165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY129_12170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY129_12175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY129_12185	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY129_12190	COG0495	leucyl-tRNA aminoacylation
FY129_12205	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY129_12210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY129_12225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY129_12230	COG1946	Acyl-CoA thioesterase
FY129_12235	COG0347	Belongs to the P(II) protein family
FY129_12240	COG0004	ammonium transporteR
FY129_12245	COG1674	ftsk spoiiie
FY129_12250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY129_12265	COG0745	RESPONSE REGULATOR receiver
FY129_12275	COG1329	Transcriptional regulator
FY129_12285	COG2270	Major facilitator Superfamily
FY129_12300	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_12315	COG0494	nUDIX hydrolase
FY129_12320	COG2861	carbohydrate metabolic process
FY129_12325	COG0793	Belongs to the peptidase S41A family
FY129_12335	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY129_12340	COG0799	negative regulation of ribosome biogenesis
FY129_12345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY129_12350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY129_12355	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY129_12360	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY129_12375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY129_12380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY129_12405	COG0066	3-isopropylmalate dehydratase activity
FY129_12410	COG0473	3-isopropylmalate dehydrogenase activity
FY129_12415	COG1858	cytochrome C peroxidase
FY129_12420	COG1797	cobyrinic acid a,c-diamide synthase activity
FY129_12430	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY129_12495	COG1492	cobalamin metabolic process
FY129_12510	COG4948	Mandelate Racemase Muconate Lactonizing
FY129_12515	COG3254	rhamnose metabolic process
FY129_12525	COG1063	alcohol dehydrogenase
FY129_12550	COG1129	ABC transporter
FY129_12555	COG2186	Transcriptional regulator
FY129_12560	COG2721	sulfolactate sulfo-lyase activity
FY129_12565	COG0138	bifunctional purine biosynthesis protein purh
FY129_12575	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY129_12575	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY129_12580	COG0501	Belongs to the peptidase M48B family
FY129_12600	COG0357	Ribosomal RNA small subunit methyltransferase G
FY129_12605	COG0445	tRNA wobble uridine modification
FY129_12610	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY129_12615	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY129_12620	COG1981	membrane
FY129_12625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY129_12630	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY129_12635	COG0424	maF-like protein
FY129_12640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY129_12645	COG0237	dephospho-CoA kinase activity
FY129_12655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY129_12660	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY129_12670	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY129_12695	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY129_12710	COG0135	phosphoribosylanthranilate isomerase activity
FY129_12715	COG0133	tryptophan synthase activity
FY129_12720	COG0159	tryptophan synthase activity
FY129_12725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY129_12740	COG1074	ATP-dependent DNA helicase activity
FY129_12750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY129_12755	COG0802	atpase or kinase
FY129_12760	COG2205	protein histidine kinase activity
FY129_12765	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY129_12770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY129_12775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY129_12775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY129_12780	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY129_12785	COG0642	Histidine kinase
FY129_12790	COG0745	RESPONSE REGULATOR receiver
FY129_12795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY129_12805	COG1652	LysM domain
FY129_12810	COG1072	(Pantothenic acid kinase))
FY129_12815	COG0140	phosphoribosyl-ATP diphosphatase activity
FY129_12820	COG0107	imidazoleglycerol-phosphate synthase activity
FY129_12825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY129_12830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY129_12840	COG0131	Imidazoleglycerol-phosphate dehydratase
FY129_12845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY129_12850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY129_12860	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY129_12875	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY129_12885	COG1643	Atp-dependent helicase
FY129_12925	COG1940	carbohydrate kinase activity
FY129_12945	COG1072	(Pantothenic acid kinase))
FY129_12955	COG1780	Probably involved in ribonucleotide reductase function
FY129_12975	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY129_13005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_13015	COG2813	Specifically methylates the guanine in position
FY129_13020	COG1185	polyribonucleotide nucleotidyltransferase activity
FY129_13025	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY129_13030	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY129_13035	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY129_13040	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY129_13040	COG3064	Membrane
FY129_13055	COG0779	Required for maturation of 30S ribosomal subunits
FY129_13060	COG2814	Major facilitator Superfamily
FY129_13070	COG2951	lytic endotransglycosylase activity
FY129_13075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY129_13085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY129_13090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY129_13105	COG2816	NAD+ diphosphatase activity
FY129_13110	COG1605	Chorismate mutase
FY129_13110	COG0077	Prephenate dehydratase
FY129_13115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY129_13120	COG3474	cytochrome
FY129_13130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY129_13135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY129_13140	COG1278	Cold shock
FY129_13145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY129_13155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY129_13155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY129_13160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY129_13190	COG2900	Belongs to the SlyX family
FY129_13200	COG0484	heat shock protein binding
FY129_13205	COG0443	Heat shock 70 kDa protein
FY129_13220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY129_13225	COG1744	ABC transporter substrate-binding protein PnrA-like
FY129_13230	COG3845	ABC transporter
FY129_13235	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY129_13240	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY129_13245	COG0295	cytidine deaminase activity
FY129_13250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY129_13255	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY129_13260	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY129_13270	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY129_13275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY129_13280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY129_13290	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY129_13295	COG1845	cytochrome c oxidase, subunit III
FY129_13300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY129_13305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY129_13310	COG0477	Major facilitator Superfamily
FY129_13315	COG0067	glutamate synthase
FY129_13315	COG0069	glutamate synthase activity
FY129_13315	COG0070	glutamate synthase
FY129_13320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY129_13335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY129_13345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY129_13375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_13395	COG0848	biopolymer transport protein
FY129_13405	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY129_13420	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY129_13425	COG3454	Phosphonate metabolism
FY129_13430	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY129_13435	COG3639	organic phosphonate transmembrane transporter activity
FY129_13440	COG3639	organic phosphonate transmembrane transporter activity
FY129_13445	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY129_13450	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY129_13460	COG4778	phosphonate C-P lyase system protein PhnL
FY129_13465	COG4107	phosphonate C-P lyase system protein PhnK
FY129_13470	COG3627	carbon phosphorus lyase activity
FY129_13475	COG3626	phosphonate metabolism
FY129_13480	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY129_13485	COG3624	Phosphonate C-P lyase system protein PhnG
FY129_13490	COG2188	Transcriptional regulator
FY129_13495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY129_13500	COG0837	glucose binding
FY129_13505	COG1803	Methylglyoxal synthase
FY129_13510	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY129_13515	COG4166	transmembrane transport
FY129_13520	COG4174	ABC transporter (Permease)
FY129_13525	COG4239	(ABC) transporter, permease
FY129_13530	COG4172	Belongs to the ABC transporter superfamily
FY129_13535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_13540	COG0174	glutamine synthetase
FY129_13545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_13550	COG3265	gluconokinase activity
FY129_13555	COG1174	glycine betaine transport
FY129_13560	COG1125	glycine betaine transport
FY129_13565	COG1174	glycine betaine transport
FY129_13570	COG1732	Glycine betaine
FY129_13580	COG1959	2 iron, 2 sulfur cluster binding
FY129_13585	COG1840	ABC-type Fe3 transport system, periplasmic component
FY129_13595	COG4269	membrane
FY129_13610	COG0697	spore germination
FY129_13625	COG0791	NLP P60 protein
FY129_13635	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY129_13640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY129_13675	COG4964	Belongs to the GSP D family
FY129_13720	COG3422	double-strand break repair
FY129_13725	COG3757	hydrolase, family 25
FY129_13730	COG0697	spore germination
FY129_13735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY129_13750	COG0492	ferredoxin-NADP+ reductase activity
FY129_13765	COG0481	GTPase activity
FY129_13770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY129_13785	COG1396	sequence-specific DNA binding
FY129_13800	COG2169	Transcriptional regulator
FY129_13800	COG1917	Cupin 2, conserved barrel domain protein
FY129_13805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY129_13830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY129_13835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY129_13840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY129_13850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY129_13855	COG0072	phenylalanine-tRNA ligase activity
FY129_13855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY129_13860	COG0667	Aldo Keto reductase
FY129_13880	COG4977	sequence-specific DNA binding
FY129_13905	COG1570	exodeoxyribonuclease VII activity
FY129_13910	COG4948	Mandelate Racemase Muconate Lactonizing
FY129_13920	COG1846	Transcriptional regulator
FY129_13925	COG0697	spore germination
FY129_13930	COG2309	aminopeptidase activity
FY129_13940	COG1393	Belongs to the ArsC family
FY129_13955	COG1309	transcriptional regulator
FY129_13965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY129_13965	COG0519	Catalyzes the synthesis of GMP from XMP
FY129_13980	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY129_14010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY129_14020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY129_14030	COG1968	undecaprenyl-diphosphatase activity
FY129_14045	COG0284	orotidine-5'-phosphate decarboxylase activity
FY129_14055	COG3963	phosphatidate phosphatase activity
FY129_14065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY129_14070	COG0792	nuclease activity
FY129_14085	COG1175	transmembrane transport
FY129_14090	COG0395	ABC-type sugar transport system, permease component
FY129_14095	COG3842	ATPase activity
FY129_14105	COG0189	ligase activity
FY129_14115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY129_14120	COG1280	lysine exporter protein (LysE YggA)
FY129_14125	COG0756	dUTP diphosphatase activity
FY129_14130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY129_14135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY129_14150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY129_14155	COG2226	methyltransferase
FY129_14160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY129_14165	COG1024	Enoyl-CoA hydratase
FY129_14170	COG0268	Binds directly to 16S ribosomal RNA
FY129_14190	COG0640	Transcriptional regulator
FY129_14225	COG4178	(ABC) transporter
FY129_14250	COG1082	Xylose isomerase domain protein TIM barrel
FY129_14255	COG0572	uridine kinase
FY129_14265	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_14270	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_14275	COG1129	ABC transporter
FY129_14295	COG3284	Transcriptional regulator
FY129_14300	COG1063	alcohol dehydrogenase
FY129_14310	COG0110	maltose O-acetyltransferase activity
FY129_14315	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY129_14340	COG0488	(ABC) transporter
FY129_14345	COG5265	(ABC) transporter
FY129_14350	COG3181	Tripartite tricarboxylate transporter family receptor
FY129_14355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY129_14365	COG3237	CsbD-like
FY129_14385	COG0395	ABC-type sugar transport system, permease component
FY129_14390	COG3842	ATPase activity
FY129_14400	COG0483	inositol monophosphate 1-phosphatase activity
FY129_14410	COG0405	Gamma-glutamyltransferase
FY129_14415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_14420	COG0601	transmembrane transport
FY129_14425	COG0747	negative chemotaxis
FY129_14430	COG2186	Transcriptional regulator
FY129_14440	COG4948	Mandelate Racemase Muconate Lactonizing
FY129_14445	COG4172	Belongs to the ABC transporter superfamily
FY129_14450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_14455	COG0601	transmembrane transport
FY129_14460	COG0747	negative chemotaxis
FY129_14465	COG2186	Transcriptional regulator
FY129_14475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_14480	COG2223	nitrite transmembrane transporter activity
FY129_14490	COG3383	formate dehydrogenase (NAD+) activity
FY129_14510	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY129_14525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY129_14535	COG0765	amino acid transport
FY129_14540	COG0765	amino acid transport
FY129_14545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_14560	COG3938	Belongs to the proline racemase family
FY129_14570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_14580	COG0765	amino acid transport
FY129_14595	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY129_14600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_14610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY129_14615	COG0784	Response regulator, receiver
FY129_14630	COG0842	Transport permease protein
FY129_14635	COG0842	Transport permease protein
FY129_14635	COG1129	ABC transporter
FY129_14640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_14645	COG1486	melibiose metabolic process
FY129_14650	COG4172	Belongs to the ABC transporter superfamily
FY129_14655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_14660	COG0601	transmembrane transport
FY129_14665	COG0747	negative chemotaxis
FY129_14670	COG1486	melibiose metabolic process
FY129_14695	COG1940	carbohydrate kinase activity
FY129_14700	COG2182	Extracellular solute-binding protein
FY129_14705	COG1175	transmembrane transport
FY129_14710	COG0395	ABC-type sugar transport system, permease component
FY129_14715	COG0165	Argininosuccinate lyase
FY129_14720	COG3842	ATPase activity
FY129_14725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_14730	COG3119	arylsulfatase activity
FY129_14740	COG0583	DNA-binding transcription factor activity
FY129_14745	COG1120	ATPase activity
FY129_14750	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_14755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_14765	COG4774	siderophore transport
FY129_14775	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY129_14790	COG2205	protein histidine kinase activity
FY129_14795	COG0745	RESPONSE REGULATOR receiver
FY129_14800	COG1566	PFAM secretion protein HlyD family protein
FY129_14815	COG1392	Phosphate transport regulator
FY129_14820	COG0306	phosphate transporter
FY129_14825	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY129_14835	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY129_14845	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_14850	COG3300	MHYT domain
FY129_14850	COG5001	Diguanylate cyclase
FY129_14870	COG2186	Transcriptional regulator
FY129_14875	COG0601	transmembrane transport
FY129_14880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_14885	COG0444	Belongs to the ABC transporter superfamily
FY129_14895	COG3842	ATPase activity
FY129_14900	COG0395	ABC-type sugar transport system, permease component
FY129_14915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY129_14915	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY129_14920	COG1609	Transcriptional regulator
FY129_14930	COG0210	DNA helicase
FY129_14935	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY129_14940	COG1088	dTDP-glucose 4,6-dehydratase activity
FY129_14945	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY129_14950	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY129_14965	COG3754	Rhamnan synthesis protein F
FY129_14990	COG0673	inositol 2-dehydrogenase activity
FY129_15000	COG0275	rRNA processing
FY129_15005	COG1132	(ABC) transporter
FY129_15015	COG0583	DNA-binding transcription factor activity
FY129_15020	COG0667	Aldo Keto reductase
FY129_15040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY129_15055	COG0300	oxidoreductase activity
FY129_15060	COG0584	glycerophosphoryl diester phosphodiesterase
FY129_15065	COG1940	carbohydrate kinase activity
FY129_15075	COG3712	iron ion homeostasis
FY129_15080	COG4774	siderophore transport
FY129_15085	COG2814	Major facilitator Superfamily
FY129_15105	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY129_15120	COG1175	transmembrane transport
FY129_15125	COG0395	ABC-type sugar transport system, permease component
FY129_15130	COG1609	Transcriptional regulator
FY129_15140	COG0673	inositol 2-dehydrogenase activity
FY129_15145	COG1082	Xylose isomerase domain protein TIM barrel
FY129_15160	COG1609	Transcriptional regulator
FY129_15165	COG0183	Belongs to the thiolase family
FY129_15170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY129_15180	COG1414	Transcriptional regulator
FY129_15195	COG0583	DNA-binding transcription factor activity
FY129_15210	COG3485	protocatechuate 3,4-dioxygenase
FY129_15215	COG3485	protocatechuate 3,4-dioxygenase
FY129_15220	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY129_15225	COG0765	amino acid transport
FY129_15230	COG0765	amino acid transport
FY129_15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_15240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_15245	COG1126	abc transporter atp-binding protein
FY129_15250	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY129_15255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY129_15280	COG4172	Belongs to the ABC transporter superfamily
FY129_15285	COG0747	negative chemotaxis
FY129_15295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_15310	COG0683	leucine binding
FY129_15325	COG0411	ABC transporter
FY129_15340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_15345	COG3962	Belongs to the TPP enzyme family
FY129_15355	COG3718	enzyme involved in inositol metabolism
FY129_15365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY129_15370	COG1609	Transcriptional regulator
FY129_15375	COG1846	Transcriptional regulator
FY129_15385	COG0523	cobalamin synthesis protein
FY129_15425	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY129_15445	COG0800	Aldolase
FY129_15450	COG2954	triphosphatase activity
FY129_15460	COG1054	Belongs to the UPF0176 family
FY129_15465	COG5001	Diguanylate cyclase
FY129_15465	COG3300	MHYT domain
FY129_15475	COG2011	ABC-type metal ion transport system permease component
FY129_15480	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY129_15485	COG0778	Nitroreductase
FY129_15495	COG2115	Belongs to the xylose isomerase family
FY129_15500	COG1070	Carbohydrate kinase
FY129_15505	COG1609	Transcriptional regulator
FY129_15525	COG1309	transcriptional regulator
FY129_15530	COG1253	flavin adenine dinucleotide binding
FY129_15535	COG0471	metal ion transport
FY129_15535	COG3273	potassium ion transport
FY129_15540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY129_15545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY129_15550	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY129_15560	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY129_15565	COG1121	(ABC) transporter
FY129_15570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY129_15575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY129_15585	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_15590	COG1414	Transcriptional regulator
FY129_15595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY129_15615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY129_15640	COG1069	ribulokinase activity
FY129_15665	COG0395	ABC-type sugar transport system, permease component
FY129_15670	COG1175	transmembrane transport
FY129_15680	COG2390	Transcriptional regulator
FY129_15685	COG4172	Belongs to the ABC transporter superfamily
FY129_15690	COG1473	amidohydrolase
FY129_15700	COG0601	transmembrane transport
FY129_15705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_15715	COG0693	protein deglycase activity
FY129_15720	COG0154	amidase activity
FY129_15725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_15735	COG0747	negative chemotaxis
FY129_15740	COG0583	DNA-binding transcription factor activity
FY129_15745	COG4608	Belongs to the ABC transporter superfamily
FY129_15750	COG0444	Belongs to the ABC transporter superfamily
FY129_15755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_15760	COG0601	transmembrane transport
FY129_15765	COG0747	negative chemotaxis
FY129_15775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY129_15780	COG1473	amidohydrolase
FY129_15785	COG2814	Major facilitator Superfamily
FY129_15790	COG0583	DNA-binding transcription factor activity
FY129_15795	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY129_15815	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_15825	COG1609	Transcriptional regulator
FY129_15830	COG0583	DNA-binding transcription factor activity
FY129_15835	COG1960	acyl-CoA dehydrogenase activity
FY129_15840	COG1629	transport
FY129_15840	COG4774	siderophore transport
FY129_15855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_15865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_15870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_15880	COG2375	cellular response to nickel ion
FY129_15890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY129_15895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY129_15895	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY129_15905	COG1169	isochorismate synthase
FY129_15910	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY129_15915	COG3433	isochorismatase activity
FY129_15915	COG1535	isochorismatase
FY129_15920	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_15935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_15940	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY129_15950	COG0583	DNA-binding transcription factor activity
FY129_15955	COG3005	denitrification pathway
FY129_15965	COG0243	molybdopterin cofactor binding
FY129_15980	COG4459	periplasmic nitrate reductase
FY129_15990	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY129_16015	COG0826	peptidase U32
FY129_16025	COG3189	MarR family transcriptional regulator
FY129_16030	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY129_16035	COG0163	prenyltransferase activity
FY129_16045	COG1845	cytochrome c oxidase, subunit III
FY129_16060	COG3256	nitric oxide reductase
FY129_16065	COG0714	Associated with various cellular activities
FY129_16125	COG0673	inositol 2-dehydrogenase activity
FY129_16135	COG1609	Transcriptional regulator
FY129_16140	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_16145	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_16150	COG1129	ABC transporter
FY129_16155	COG1879	ABC-type sugar transport system periplasmic component
FY129_16165	COG0583	DNA-binding transcription factor activity
FY129_16170	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_16180	COG1609	Transcriptional regulator
FY129_16185	COG0673	inositol 2-dehydrogenase activity
FY129_16200	COG1175	transmembrane transport
FY129_16205	COG0395	ABC-type sugar transport system, permease component
FY129_16210	COG3842	ATPase activity
FY129_16225	COG1253	flavin adenine dinucleotide binding
FY129_16250	COG3300	MHYT domain
FY129_16250	COG5001	Diguanylate cyclase
FY129_16380	COG0477	Major facilitator Superfamily
FY129_16400	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_16410	COG1879	ABC-type sugar transport system periplasmic component
FY129_16420	COG1063	alcohol dehydrogenase
FY129_16435	COG1136	(ABC) transporter
FY129_16450	COG1309	transcriptional regulator
FY129_16465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY129_16475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY129_16475	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY129_16485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_16490	COG0047	phosphoribosylformylglycinamidine synthase activity
FY129_16500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_16505	COG1012	belongs to the aldehyde dehydrogenase family
FY129_16510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_16520	COG4175	Glycine betaine
FY129_16520	COG3448	diguanylate cyclase activity
FY129_16525	COG4176	ABC-type proline glycine betaine transport system permease component
FY129_16530	COG4176	ABC-type proline glycine betaine transport system permease component
FY129_16535	COG3938	Belongs to the proline racemase family
FY129_16540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY129_16575	COG1733	regulation of RNA biosynthetic process
FY129_16585	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FY129_16615	COG0405	Gamma-glutamyltransferase
FY129_16625	COG0477	Major facilitator Superfamily
FY129_16635	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY129_16640	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY129_16655	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_16665	COG0395	ABC-type sugar transport system, permease component
FY129_16690	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_16695	COG1349	DNA-binding transcription factor activity
FY129_16700	COG1069	ribulokinase activity
FY129_16720	COG1940	carbohydrate kinase activity
FY129_16735	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_16740	COG1177	transmembrane transport
FY129_16750	COG3842	ATPase activity
FY129_16805	COG0577	efflux transmembrane transporter activity
FY129_16805	COG1136	(ABC) transporter
FY129_16830	COG1845	cytochrome c oxidase, subunit III
FY129_16835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY129_16840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY129_16870	COG3842	ATPase activity
FY129_16875	COG0395	ABC-type sugar transport system, permease component
FY129_16880	COG1175	transmembrane transport
FY129_16885	COG1653	transport
FY129_16890	COG1012	belongs to the aldehyde dehydrogenase family
FY129_16895	COG1024	Enoyl-CoA hydratase
FY129_16915	COG4702	Belongs to the UPF0303 family
FY129_16920	COG4774	siderophore transport
FY129_16920	COG1629	transport
FY129_16925	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY129_16930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_16935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_16940	COG1120	ATPase activity
FY129_16955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY129_16965	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY129_16970	COG1177	transmembrane transport
FY129_16975	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_16980	COG3842	ATPase activity
FY129_17005	COG1335	isochorismatase
FY129_17020	COG0583	DNA-binding transcription factor activity
FY129_17025	COG2318	DinB family
FY129_17050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY129_17080	COG0778	Nitroreductase
FY129_17100	COG0277	FAD linked oxidase domain protein
FY129_17120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_17125	COG4172	Belongs to the ABC transporter superfamily
FY129_17135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_17145	COG0431	NADPH-dependent FMN reductase
FY129_17165	COG1522	sequence-specific DNA binding
FY129_17170	COG2376	Dihydroxyacetone kinase
FY129_17180	COG4221	oxidoreductase activity
FY129_17185	COG0625	glutathione transferase activity
FY129_17205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY129_17210	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY129_17225	COG0534	Mate efflux family protein
FY129_17260	COG1733	regulation of RNA biosynthetic process
FY129_17270	COG0577	efflux transmembrane transporter activity
FY129_17270	COG1136	(ABC) transporter
FY129_17275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_17285	COG0745	RESPONSE REGULATOR receiver
FY129_17305	COG3209	COG3209 Rhs family protein
FY129_17335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_17360	COG3177	Filamentation induced by cAMP protein fic
FY129_17375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_17380	COG4597	amino acid ABC transporter
FY129_17385	COG0765	amino acid transport
FY129_17405	COG0747	negative chemotaxis
FY129_17410	COG0601	transmembrane transport
FY129_17415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_17420	COG0444	Belongs to the ABC transporter superfamily
FY129_17425	COG4608	Belongs to the ABC transporter superfamily
FY129_17445	COG4213	ABC transporter substrate-binding protein
FY129_17450	COG1129	ABC transporter
FY129_17455	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_17470	COG0667	Aldo Keto reductase
FY129_17495	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_17500	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_17505	COG1129	ABC transporter
FY129_17515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_17525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_17535	COG0747	negative chemotaxis
FY129_17540	COG0747	negative chemotaxis
FY129_17545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_17555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_17560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_17565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY129_17590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_17595	COG0436	Aminotransferase
FY129_17610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_17615	COG0765	amino acid transport
FY129_17625	COG1126	abc transporter atp-binding protein
FY129_17635	COG2186	Transcriptional regulator
FY129_17655	COG1846	Transcriptional regulator
FY129_17660	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_17670	COG0583	DNA-binding transcription factor activity
FY129_17705	COG0583	DNA-binding transcription factor activity
FY129_17725	COG1280	lysine exporter protein (LysE YggA)
FY129_17730	COG3920	Histidine kinase
FY129_17755	COG0753	catalase activity
FY129_17775	COG1278	Cold shock
FY129_17815	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_17820	COG1902	pentaerythritol trinitrate reductase activity
FY129_17825	COG4221	oxidoreductase activity
FY129_17830	COG1309	transcriptional regulator
FY129_17845	COG1280	lysine exporter protein (LysE YggA)
FY129_17855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY129_17900	COG1196	nuclear chromosome segregation
FY129_17900	COG0741	lytic transglycosylase activity
FY129_17900	COG0739	heme binding
FY129_17905	COG0542	response to heat
FY129_17915	COG2890	protein-(glutamine-N5) methyltransferase activity
FY129_17920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY129_17930	COG0527	aspartate kinase activity
FY129_17945	COG0019	diaminopimelate decarboxylase activity
FY129_17960	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY129_17970	COG3920	Histidine kinase
FY129_17980	COG0784	Response regulator, receiver
FY129_17995	COG1522	sequence-specific DNA binding
FY129_18005	COG1116	anion transmembrane transporter activity
FY129_18010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_18015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY129_18020	COG1012	belongs to the aldehyde dehydrogenase family
FY129_18025	COG0583	DNA-binding transcription factor activity
FY129_18030	COG0435	Glutathione S-transferase
FY129_18040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY129_18045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY129_18050	COG0189	ligase activity
FY129_18070	COG0693	protein deglycase activity
FY129_18100	COG3685	Protein conserved in bacteria
FY129_18105	COG4993	Dehydrogenase
FY129_18120	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_18125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY129_18170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_18195	COG1475	DNA binding
FY129_18235	COG4396	Host-nuclease inhibitor protein Gam
FY129_18270	COG3179	chitinase
FY129_18300	COG2369	cell adhesion
FY129_18455	COG0246	Mannitol dehydrogenase
FY129_18460	COG4608	Belongs to the ABC transporter superfamily
FY129_18465	COG0444	Belongs to the ABC transporter superfamily
FY129_18470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_18475	COG0601	transmembrane transport
FY129_18480	COG0747	negative chemotaxis
FY129_18490	COG4221	oxidoreductase activity
FY129_18520	COG0539	negative regulation of cytoplasmic translation
FY129_18525	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY129_18555	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY129_18560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY129_18590	COG1294	oxidase, subunit
FY129_18600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY129_18605	COG4988	ABC transporter
FY129_18615	COG1063	alcohol dehydrogenase
FY129_18620	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_18625	COG2084	Dehydrogenase
FY129_18635	COG1522	sequence-specific DNA binding
FY129_18640	COG1794	racemase activity, acting on amino acids and derivatives
FY129_18655	COG0058	SHG alpha-glucan phosphorylase activity
FY129_18660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY129_18665	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY129_18670	COG0297	glycogen (starch) synthase activity
FY129_18675	COG0033	Phosphoglucomutase
FY129_18680	COG1523	belongs to the glycosyl hydrolase 13 family
FY129_18710	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY129_18710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY129_18725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_18730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY129_18750	COG1215	transferase activity, transferring glycosyl groups
FY129_18755	COG2327	Polysaccharide pyruvyl transferase
FY129_18760	COG0463	Glycosyl transferase, family 2
FY129_18765	COG2244	polysaccharide biosynthetic process
FY129_18770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY129_18775	COG2273	Hydrolase Family 16
FY129_18780	COG0438	transferase activity, transferring glycosyl groups
FY129_18785	COG1215	transferase activity, transferring glycosyl groups
FY129_18790	COG1215	transferase activity, transferring glycosyl groups
FY129_18795	COG1215	transferase activity, transferring glycosyl groups
FY129_18800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY129_18805	COG3206	protein involved in exopolysaccharide biosynthesis
FY129_18805	COG0489	protein tyrosine kinase activity
FY129_18810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY129_18815	COG0784	Response regulator, receiver
FY129_18815	COG4191	Histidine kinase
FY129_18830	COG4176	ABC-type proline glycine betaine transport system permease component
FY129_18835	COG3448	diguanylate cyclase activity
FY129_18835	COG4175	Glycine betaine
FY129_18850	COG0564	pseudouridine synthase activity
FY129_18855	COG0500	methyltransferase
FY129_18865	COG2133	pyrroloquinoline quinone binding
FY129_18875	COG2197	response regulator
FY129_18880	COG4585	Histidine kinase
FY129_18885	COG1879	ABC-type sugar transport system periplasmic component
FY129_18890	COG1129	ABC transporter
FY129_18895	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_18905	COG3386	PFAM SMP-30 Gluconolaconase
FY129_18910	COG2137	regulation of response to DNA damage stimulus
FY129_18915	COG3474	cytochrome
FY129_18925	COG1120	ATPase activity
FY129_18940	COG4774	siderophore transport
FY129_18945	COG0583	DNA-binding transcription factor activity
FY129_18955	COG2194	sulfuric ester hydrolase activity
FY129_18970	COG0477	Major facilitator Superfamily
FY129_18995	COG0673	inositol 2-dehydrogenase activity
FY129_19000	COG0697	spore germination
FY129_19010	COG0010	Belongs to the arginase family
FY129_19025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY129_19030	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY129_19035	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY129_19040	COG0156	8-amino-7-oxononanoate synthase activity
FY129_19045	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY129_19095	COG0671	phosphoesterase, PA-phosphatase related
FY129_19100	COG0745	RESPONSE REGULATOR receiver
FY129_19105	COG2205	protein histidine kinase activity
FY129_19115	COG0477	Major facilitator Superfamily
FY129_19120	COG0583	DNA-binding transcription factor activity
FY129_19140	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY129_19155	COG0346	lactoylglutathione lyase activity
FY129_19160	COG0583	DNA-binding transcription factor activity
FY129_19190	COG1215	transferase activity, transferring glycosyl groups
FY129_19210	COG0840	transmembrane signaling receptor activity
FY129_19225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_19240	COG2828	Protein conserved in bacteria
FY129_19245	COG0583	DNA-binding transcription factor activity
FY129_19250	COG1846	Transcriptional regulator
FY129_19275	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_19280	COG1309	transcriptional regulator
FY129_19285	COG2207	Transcriptional regulator
FY129_19300	COG1566	PFAM secretion protein HlyD family protein
FY129_19315	COG0395	ABC-type sugar transport system, permease component
FY129_19320	COG4166	transmembrane transport
FY129_19325	COG0601	transmembrane transport
FY129_19330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_19335	COG4172	Belongs to the ABC transporter superfamily
FY129_19380	COG0402	S-adenosylhomocysteine deaminase activity
FY129_19385	COG1228	amidohydrolase
FY129_19390	COG2986	histidine ammonia-lyase
FY129_19400	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY129_19430	COG1192	Involved in chromosome partitioning
FY129_19435	COG1475	DNA binding
FY129_19440	COG1414	Transcriptional regulator
FY129_19460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY129_19465	COG4771	TonB-dependent receptor
FY129_19475	COG0366	Alpha amylase catalytic
FY129_19480	COG4770	biotin carboxylase activity
FY129_19485	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY129_19490	COG4336	lyase activity
FY129_19495	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY129_19500	COG1914	H( )-stimulated, divalent metal cation uptake system
FY129_19505	COG1802	Transcriptional regulator
FY129_19510	COG3707	response regulator
FY129_19520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY129_19525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_19530	COG1116	anion transmembrane transporter activity
FY129_19535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY129_19545	COG0243	molybdopterin cofactor binding
FY129_19550	COG1648	precorrin-2 dehydrogenase activity
FY129_19550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY129_19565	COG3842	ATPase activity
FY129_19580	COG0395	ABC-type sugar transport system, permease component
FY129_19595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY129_19610	COG0071	Belongs to the small heat shock protein (HSP20) family
FY129_19650	COG1129	ABC transporter
FY129_19655	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_19665	COG0667	Aldo Keto reductase
FY129_19670	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY129_19675	COG1830	Aldolase
FY129_19680	COG1070	Carbohydrate kinase
FY129_19685	COG2972	Histidine kinase
FY129_19685	COG0840	transmembrane signaling receptor activity
FY129_19700	COG0436	Aminotransferase
FY129_19710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY129_19720	COG3842	ATPase activity
FY129_19725	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY129_19730	COG1984	allophanate hydrolase subunit 2
FY129_19735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY129_19745	COG0439	Biotin carboxylase
FY129_19750	COG0511	ligase activity, forming carbon-carbon bonds
FY129_19755	COG0697	spore germination
FY129_19760	COG0697	spore germination
FY129_19775	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY129_19790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY129_19795	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_19800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY129_19805	COG4221	oxidoreductase activity
FY129_19810	COG0765	amino acid transport
FY129_19815	COG0765	amino acid transport
FY129_19825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_19830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY129_19835	COG1063	alcohol dehydrogenase
FY129_19850	COG1304	FMN binding
FY129_19875	COG3842	ATPase activity
FY129_19885	COG0395	ABC-type sugar transport system, permease component
FY129_19890	COG1175	transmembrane transport
FY129_19905	COG2186	Transcriptional regulator
FY129_19910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY129_19915	COG0488	(ABC) transporter
FY129_19930	COG2308	Evidence 4 Homologs of previously reported genes of
FY129_19930	COG2307	Protein conserved in bacteria
FY129_19970	COG1454	alcohol dehydrogenase
FY129_19975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY129_19985	COG0747	negative chemotaxis
FY129_19990	COG0601	transmembrane transport
FY129_19995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_20000	COG4172	Belongs to the ABC transporter superfamily
FY129_20005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_20110	COG1082	Xylose isomerase domain protein TIM barrel
FY129_20115	COG1082	Xylose isomerase domain protein TIM barrel
FY129_20120	COG0673	inositol 2-dehydrogenase activity
FY129_20125	COG1082	Xylose isomerase domain protein TIM barrel
FY129_20145	COG1609	Transcriptional regulator
FY129_20150	COG2986	histidine ammonia-lyase
FY129_20155	COG4175	Glycine betaine
FY129_20155	COG0517	IMP dehydrogenase activity
FY129_20160	COG4176	ABC-type proline glycine betaine transport system permease component
FY129_20180	COG1309	transcriptional regulator
FY129_20200	COG2186	Transcriptional regulator
FY129_20205	COG1027	Aspartate ammonia-lyase
FY129_20215	COG0252	asparaginase activity
FY129_20225	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY129_20230	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY129_20235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY129_20240	COG2205	protein histidine kinase activity
FY129_20255	COG0067	glutamate synthase
FY129_20255	COG0069	glutamate synthase activity
FY129_20255	COG0070	glutamate synthase
FY129_20270	COG2205	protein histidine kinase activity
FY129_20285	COG2951	lytic endotransglycosylase activity
FY129_20290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY129_20320	COG0330	HflC and HflK could
FY129_20325	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY129_20330	COG0737	Belongs to the 5'-nucleotidase family
FY129_20340	COG5310	Homospermidine synthase
FY129_20350	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY129_20355	COG1164	Oligoendopeptidase f
FY129_20360	COG2204	response regulator
FY129_20365	COG3108	Peptidase M15
FY129_20370	COG0469	pyruvate kinase activity
FY129_20390	COG3750	Belongs to the UPF0335 family
FY129_20400	COG0457	Tetratricopeptide repeat
FY129_20405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY129_20410	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY129_20415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY129_20445	COG0483	inositol monophosphate 1-phosphatase activity
FY129_20470	COG1132	(ABC) transporter
FY129_20475	COG0254	rRNA binding
FY129_20495	COG3588	fructose-bisphosphate aldolase
FY129_20500	COG0126	phosphoglycerate kinase activity
FY129_20540	COG1253	flavin adenine dinucleotide binding
FY129_20550	COG1692	metallophosphoesterase
FY129_20565	COG0217	transcriptional regulatory protein
FY129_20570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_20575	COG0840	transmembrane signaling receptor activity
FY129_20580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY129_20585	COG0632	four-way junction helicase activity
FY129_20590	COG2255	four-way junction helicase activity
FY129_20605	COG0494	nUDIX hydrolase
FY129_20615	COG0824	Thioesterase
FY129_20635	COG0823	Involved in the tonB-independent uptake of proteins
FY129_20640	COG2885	chlorophyll binding
FY129_20650	COG0037	tRNA processing
FY129_20655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY129_20660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY129_20675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY129_20690	COG0482	sulfurtransferase activity
FY129_20725	COG2835	tetraacyldisaccharide 4'-kinase activity
FY129_20730	COG2373	Large extracellular alpha-helical protein
FY129_20735	COG4953	penicillin-binding protein 1C
FY129_20835	COG3750	Belongs to the UPF0335 family
FY129_20950	COG0393	Putative heavy-metal-binding
FY129_21030	COG1473	amidohydrolase
FY129_21035	COG1686	Belongs to the peptidase S11 family
FY129_21040	COG0523	cobalamin synthesis protein
FY129_21045	COG0425	Belongs to the sulfur carrier protein TusA family
FY129_21045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY129_21050	COG3034	peptidoglycan biosynthetic process
FY129_21055	COG0825	malonyl-CoA metabolic process
FY129_21060	COG4974	Belongs to the 'phage' integrase family
FY129_21070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY129_21075	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY129_21115	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY129_21120	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY129_21140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY129_21145	COG2226	methyltransferase
FY129_21150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY129_21155	COG0287	Prephenate dehydrogenase
FY129_21165	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY129_21185	COG2884	Cell division ATP-binding protein ftsE
FY129_21220	COG0165	Argininosuccinate lyase
FY129_21225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY129_21235	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY129_21245	COG2086	electron transfer activity
FY129_21255	COG2096	Adenosyltransferase
FY129_21265	COG0300	oxidoreductase activity
FY129_21275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY129_21285	COG1396	sequence-specific DNA binding
FY129_21285	COG3800	Transcriptional regulator
FY129_21290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY129_21295	COG0625	glutathione transferase activity
FY129_21310	COG4770	biotin carboxylase activity
FY129_21315	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY129_21315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY129_21320	COG0346	lactoylglutathione lyase activity
FY129_21335	COG4213	ABC transporter substrate-binding protein
FY129_21340	COG4214	carbohydrate transport
FY129_21345	COG1129	ABC transporter
FY129_21350	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY129_21360	COG1396	sequence-specific DNA binding
FY129_21415	COG3833	ABC-type maltose transport systems, permease component
FY129_21420	COG3842	ATPase activity
FY129_21435	COG2273	Hydrolase Family 16
FY129_21435	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY129_21440	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY129_21455	COG0438	transferase activity, transferring glycosyl groups
FY129_21460	COG0438	transferase activity, transferring glycosyl groups
FY129_21465	COG0438	transferase activity, transferring glycosyl groups
FY129_21480	COG0489	protein tyrosine kinase activity
FY129_21480	COG3206	protein involved in exopolysaccharide biosynthesis
FY129_21490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY129_21505	COG2244	polysaccharide biosynthetic process
FY129_21570	COG0697	spore germination
FY129_21575	COG0653	protein targeting
FY129_21580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY129_21585	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY129_21595	COG0494	nUDIX hydrolase
FY129_21610	COG2226	methyltransferase
FY129_21615	COG1040	competence protein
FY129_21625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY129_21635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY129_21650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY129_21655	COG4150	thiosulfate binding
FY129_21665	COG4208	sulfate ABC transporter
FY129_21670	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY129_21675	COG4335	DNA alkylation repair
FY129_21690	COG5001	Diguanylate cyclase
FY129_21695	COG2264	protein methyltransferase activity
FY129_21710	COG3254	rhamnose metabolic process
FY129_21715	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_21720	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_21725	COG1129	ABC transporter
FY129_21735	COG1349	DNA-binding transcription factor activity
FY129_21740	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_21740	COG3347	Dehydrogenase
FY129_21745	COG4952	isomerase
FY129_21750	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY129_21755	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY129_21760	COG1024	Enoyl-CoA hydratase
FY129_21775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY129_21780	COG1960	acyl-CoA dehydrogenase activity
FY129_21790	COG0183	Belongs to the thiolase family
FY129_21795	COG1960	acyl-CoA dehydrogenase activity
FY129_21805	COG0022	dehydrogenase e1 component
FY129_21815	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY129_21820	COG2391	methyltransferase activity
FY129_21830	COG0640	Transcriptional regulator
FY129_21835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY129_21835	COG3453	Protein conserved in bacteria
FY129_21845	COG0300	oxidoreductase activity
FY129_21860	COG2186	Transcriptional regulator
FY129_21870	COG0601	transmembrane transport
FY129_21880	COG0444	Belongs to the ABC transporter superfamily
FY129_21885	COG4608	Belongs to the ABC transporter superfamily
FY129_21905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_21910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_21925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_21930	COG1473	amidohydrolase
FY129_21935	COG0747	negative chemotaxis
FY129_21945	COG4166	transmembrane transport
FY129_21950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_21955	COG0583	DNA-binding transcription factor activity
FY129_21965	COG0667	Aldo Keto reductase
FY129_21975	COG0444	Belongs to the ABC transporter superfamily
FY129_21990	COG0747	negative chemotaxis
FY129_22000	COG1960	acyl-CoA dehydrogenase activity
FY129_22030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_22035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY129_22045	COG1959	2 iron, 2 sulfur cluster binding
FY129_22050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_22055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_22060	COG1473	amidohydrolase
FY129_22070	COG1126	abc transporter atp-binding protein
FY129_22075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_22085	COG0583	DNA-binding transcription factor activity
FY129_22100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_22110	COG1522	sequence-specific DNA binding
FY129_22115	COG4172	Belongs to the ABC transporter superfamily
FY129_22120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_22155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_22160	COG1012	belongs to the aldehyde dehydrogenase family
FY129_22165	COG0473	3-isopropylmalate dehydrogenase activity
FY129_22170	COG1012	belongs to the aldehyde dehydrogenase family
FY129_22215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_22220	COG1120	ATPase activity
FY129_22230	COG2226	methyltransferase
FY129_22245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_22250	COG1120	ATPase activity
FY129_22255	COG1595	DNA-templated transcription, initiation
FY129_22275	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY129_22280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_22300	COG0673	inositol 2-dehydrogenase activity
FY129_22305	COG0673	inositol 2-dehydrogenase activity
FY129_22315	COG1175	transmembrane transport
FY129_22320	COG0395	ABC-type sugar transport system, permease component
FY129_22325	COG3842	ATPase activity
FY129_22335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY129_22340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY129_22345	COG2197	response regulator
FY129_22350	COG0601	transmembrane transport
FY129_22355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_22375	COG0747	negative chemotaxis
FY129_22390	COG1446	asparaginase
FY129_22395	COG0583	DNA-binding transcription factor activity
FY129_22400	COG0601	transmembrane transport
FY129_22405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_22420	COG0747	negative chemotaxis
FY129_22425	COG1473	amidohydrolase
FY129_22440	COG1129	ABC transporter
FY129_22445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_22450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY129_22455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY129_22465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY129_22480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_22490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_22495	COG2079	MmgE PrpD family protein
FY129_22500	COG1126	abc transporter atp-binding protein
FY129_22505	COG0765	amino acid transport
FY129_22520	COG0281	malic enzyme
FY129_22520	COG0280	phosphate acetyltransferase
FY129_22525	COG0583	DNA-binding transcription factor activity
FY129_22550	COG1175	transmembrane transport
FY129_22555	COG0395	ABC-type sugar transport system, permease component
FY129_22570	COG0673	inositol 2-dehydrogenase activity
FY129_22575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY129_22580	COG0720	synthase
FY129_22585	COG0602	queuosine metabolic process
FY129_22590	COG0673	inositol 2-dehydrogenase activity
FY129_22600	COG3842	ATPase activity
FY129_22615	COG1653	transport
FY129_22620	COG1609	Transcriptional regulator
FY129_22635	COG2094	Belongs to the DNA glycosylase MPG family
FY129_22645	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_22655	COG1376	ErfK ybiS ycfS ynhG family protein
FY129_22660	COG0840	transmembrane signaling receptor activity
FY129_22660	COG2972	Histidine kinase
FY129_22665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY129_22675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY129_22680	COG1596	polysaccharide export
FY129_22685	COG3307	-O-antigen
FY129_22715	COG2197	response regulator
FY129_22725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY129_22750	COG2942	2-epimerase
FY129_22760	COG1215	transferase activity, transferring glycosyl groups
FY129_22780	COG1473	amidohydrolase
FY129_22790	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_22795	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY129_22800	COG1301	dicarboxylic acid transport
FY129_22805	COG4191	Histidine kinase
FY129_22810	COG2204	response regulator
FY129_22825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_22830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY129_22835	COG1522	sequence-specific DNA binding
FY129_22840	COG0351	phosphomethylpyrimidine kinase
FY129_22845	COG0352	thiamine-phosphate diphosphorylase activity
FY129_22850	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY129_22855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY129_22860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_22870	COG1501	Belongs to the glycosyl hydrolase 31 family
FY129_22875	COG0395	ABC-type sugar transport system, permease component
FY129_22880	COG1175	transmembrane transport
FY129_22885	COG1653	transport
FY129_22890	COG3842	ATPase activity
FY129_22895	COG2188	Transcriptional regulator
FY129_22905	COG4989	oxidoreductase activity
FY129_22940	COG0438	transferase activity, transferring glycosyl groups
FY129_22945	COG0747	negative chemotaxis
FY129_22950	COG0601	transmembrane transport
FY129_22960	COG3964	amidohydrolase
FY129_22975	COG1921	L-seryl-tRNASec selenium transferase activity
FY129_22980	COG4172	Belongs to the ABC transporter superfamily
FY129_22985	COG0625	glutathione transferase activity
FY129_23000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_23005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY129_23005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY129_23010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY129_23030	COG1312	Catalyzes the dehydration of D-mannonate
FY129_23035	COG1063	alcohol dehydrogenase
FY129_23040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY129_23050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY129_23055	COG2186	Transcriptional regulator
FY129_23060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY129_23065	COG0850	regulation of cytokinetic process
FY129_23070	COG2894	cell division
FY129_23075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY129_23080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_23090	COG5001	Diguanylate cyclase
FY129_23105	COG0673	inositol 2-dehydrogenase activity
FY129_23115	COG1653	transport
FY129_23120	COG1175	transmembrane transport
FY129_23125	COG0395	ABC-type sugar transport system, permease component
FY129_23130	COG3842	ATPase activity
FY129_23140	COG0673	inositol 2-dehydrogenase activity
FY129_23170	COG0587	DNA-directed DNA polymerase activity
FY129_23175	COG2226	methyltransferase
FY129_23190	COG2186	Transcriptional regulator
FY129_23195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_23200	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_23205	COG1129	ABC transporter
FY129_23210	COG1879	ABC-type sugar transport system periplasmic component
FY129_23215	COG0129	dihydroxy-acid dehydratase activity
FY129_23225	COG0346	lactoylglutathione lyase activity
FY129_23240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY129_23245	COG4608	Belongs to the ABC transporter superfamily
FY129_23255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_23260	COG0601	transmembrane transport
FY129_23265	COG0747	negative chemotaxis
FY129_23270	COG1674	ftsk spoiiie
FY129_23275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY129_23280	COG5001	Diguanylate cyclase
FY129_23290	COG3257	ureidoglycine aminohydrolase activity
FY129_23300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_23305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY129_23315	COG1129	ABC transporter
FY129_23320	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_23325	COG1879	ABC-type sugar transport system periplasmic component
FY129_23330	COG0583	DNA-binding transcription factor activity
FY129_23355	COG3047	cAMP biosynthetic process
FY129_23365	COG3842	ATPase activity
FY129_23370	COG0395	ABC-type sugar transport system, permease component
FY129_23375	COG1175	transmembrane transport
FY129_23380	COG1653	transport
FY129_23385	COG0523	cobalamin synthesis protein
FY129_23400	COG0523	cobalamin synthesis protein
FY129_23405	COG1121	(ABC) transporter
FY129_23415	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY129_23420	COG0454	-acetyltransferase
FY129_23435	COG0626	cystathionine gamma-synthase activity
FY129_23440	COG2182	Extracellular solute-binding protein
FY129_23450	COG0395	ABC-type sugar transport system, permease component
FY129_23465	COG0395	ABC-type sugar transport system, permease component
FY129_23470	COG1175	transmembrane transport
FY129_23475	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY129_23480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY129_23490	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_23495	COG1063	alcohol dehydrogenase
FY129_23500	COG1609	Transcriptional regulator
FY129_23505	COG2223	nitrite transmembrane transporter activity
FY129_23510	COG4977	sequence-specific DNA binding
FY129_23540	COG0667	Aldo Keto reductase
FY129_23555	COG2186	Transcriptional regulator
FY129_23560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY129_23565	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY129_23570	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_23575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY129_23580	COG4948	Mandelate Racemase Muconate Lactonizing
FY129_23585	COG3618	amidohydrolase
FY129_23595	COG1175	transmembrane transport
FY129_23600	COG0395	ABC-type sugar transport system, permease component
FY129_23605	COG3842	ATPase activity
FY129_23620	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY129_23625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY129_23645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY129_23655	COG1278	Cold shock
FY129_23660	COG0673	inositol 2-dehydrogenase activity
FY129_23675	COG0673	inositol 2-dehydrogenase activity
FY129_23680	COG1309	transcriptional regulator
FY129_23685	COG1653	transport
FY129_23690	COG1175	transmembrane transport
FY129_23695	COG0395	ABC-type sugar transport system, permease component
FY129_23700	COG3842	ATPase activity
FY129_23715	COG1082	Xylose isomerase domain protein TIM barrel
FY129_23730	COG1609	Transcriptional regulator
FY129_23760	COG1175	transmembrane transport
FY129_23765	COG0395	ABC-type sugar transport system, permease component
FY129_23770	COG1116	anion transmembrane transporter activity
FY129_23775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_23780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY129_23795	COG3842	ATPase activity
FY129_23800	COG0395	ABC-type sugar transport system, permease component
FY129_23810	COG1653	transport
FY129_23845	COG3842	ATPase activity
FY129_23855	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_23860	COG0395	ABC-type sugar transport system, permease component
FY129_23920	COG2233	PERMEase
FY129_23935	COG5002	protein histidine kinase activity
FY129_23940	COG0745	RESPONSE REGULATOR receiver
FY129_23945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY129_23950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY129_23955	COG0702	epimerase
FY129_23965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY129_24000	COG2235	arginine
FY129_24010	COG0628	permease
FY129_24035	COG1522	sequence-specific DNA binding
FY129_24055	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_24070	COG1414	Transcriptional regulator
FY129_24080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY129_24100	COG2140	Oxalate decarboxylase
FY129_24110	COG4566	intracellular signal transduction
FY129_24115	COG4566	intracellular signal transduction
FY129_24125	COG0243	molybdopterin cofactor binding
FY129_24130	COG0783	Belongs to the Dps family
FY129_24145	COG0596	Alpha beta hydrolase
FY129_24155	COG1764	response to oxidative stress
FY129_24170	COG0596	Alpha beta hydrolase
FY129_24205	COG4172	Belongs to the ABC transporter superfamily
FY129_24230	COG0601	transmembrane transport
FY129_24235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_24240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY129_24255	COG4106	trans-aconitate 2-methyltransferase activity
FY129_24260	COG0025	NhaP-type Na H and K H
FY129_24265	COG4302	ethanolamine ammonia-lyase activity
FY129_24290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY129_24295	COG1349	DNA-binding transcription factor activity
FY129_24300	COG4608	Belongs to the ABC transporter superfamily
FY129_24310	COG0601	transmembrane transport
FY129_24315	COG0747	negative chemotaxis
FY129_24320	COG1454	alcohol dehydrogenase
FY129_24325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY129_24330	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY129_24335	COG0411	ABC transporter
FY129_24375	COG1192	Involved in chromosome partitioning
FY129_24380	COG1475	DNA binding
FY129_24385	COG0640	Transcriptional regulator
FY129_24400	COG1126	abc transporter atp-binding protein
FY129_24405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY129_24410	COG1609	Transcriptional regulator
FY129_24445	COG3239	Fatty acid desaturase
FY129_24455	COG1278	Cold shock
FY129_24530	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY129_24530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY129_24565	COG4191	Histidine kinase
FY129_24570	COG1132	(ABC) transporter
FY129_24580	COG0640	Transcriptional regulator
FY129_24610	COG4977	sequence-specific DNA binding
FY129_24615	COG2211	Major facilitator Superfamily
FY129_24620	COG2807	transmembrane transport
FY129_24625	COG1846	Transcriptional regulator
FY129_24640	COG2814	Major facilitator Superfamily
FY129_24670	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY129_24685	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY129_24690	COG0583	DNA-binding transcription factor activity
FY129_24705	COG0071	Belongs to the small heat shock protein (HSP20) family
FY129_24750	COG3838	Conjugal transfer protein Trbc
FY129_24755	COG3702	type iv secretory pathway
FY129_24760	COG3451	type IV secretory pathway VirB4
FY129_24775	COG3704	protein secretion by the type IV secretion system
FY129_24785	COG3736	Type IV secretory pathway, component VirB8
FY129_24790	COG3504	Conjugal transfer protein
FY129_24795	COG2948	multi-organism process
FY129_24800	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY129_24900	COG3831	ATPase activity
FY129_24915	COG3505	Type IV secretory pathway VirD4
FY129_24940	COG0583	DNA-binding transcription factor activity
FY129_24980	COG0745	RESPONSE REGULATOR receiver
FY129_25020	COG3842	ATPase activity
FY129_25025	COG4208	sulfate ABC transporter
FY129_25030	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY129_25050	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY129_25055	COG1942	4-Oxalocrotonate Tautomerase
FY129_25065	COG3971	2-oxopent-4-enoate hydratase activity
FY129_25075	COG1414	Transcriptional regulator
FY129_25085	COG1137	ATPase activity
FY129_25100	COG4177	L-phenylalanine transmembrane transporter activity
FY129_25120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY129_25125	COG1175	transmembrane transport
FY129_25130	COG0395	ABC-type sugar transport system, permease component
FY129_25140	COG0366	Alpha amylase catalytic
FY129_25145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY129_25150	COG1082	Xylose isomerase domain protein TIM barrel
FY129_25155	COG3842	ATPase activity
FY129_25165	COG1940	carbohydrate kinase activity
FY129_25170	COG0395	ABC-type sugar transport system, permease component
FY129_25180	COG2182	Extracellular solute-binding protein
FY129_25185	COG0673	inositol 2-dehydrogenase activity
FY129_25215	COG1126	abc transporter atp-binding protein
FY129_25220	COG0765	amino acid transport
FY129_25225	COG0765	amino acid transport
FY129_25235	COG4608	Belongs to the ABC transporter superfamily
FY129_25245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_25260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY129_25265	COG0583	DNA-binding transcription factor activity
FY129_25270	COG2423	ornithine cyclodeaminase activity
FY129_25280	COG1957	nucleoside hydrolase
FY129_25300	COG1335	isochorismatase
FY129_25305	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_25350	COG0583	DNA-binding transcription factor activity
FY129_25355	COG1902	pentaerythritol trinitrate reductase activity
FY129_25360	COG0583	DNA-binding transcription factor activity
FY129_25365	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_25375	COG1335	isochorismatase
FY129_25380	COG0583	DNA-binding transcription factor activity
FY129_25390	COG1695	Transcriptional regulator
FY129_25470	COG2207	Transcriptional regulator
FY129_25515	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_25530	COG1802	Transcriptional regulator
FY129_25535	COG3485	protocatechuate 3,4-dioxygenase
FY129_25540	COG3971	2-oxopent-4-enoate hydratase activity
FY129_25555	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY129_25560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY129_25575	COG1063	alcohol dehydrogenase
FY129_25585	COG1960	acyl-CoA dehydrogenase activity
FY129_25590	COG1024	Enoyl-CoA hydratase
FY129_25600	COG1012	belongs to the aldehyde dehydrogenase family
FY129_25605	COG0477	Major facilitator Superfamily
FY129_25620	COG3706	GGDEF domain
FY129_25640	COG1846	Transcriptional regulator
FY129_25680	COG1012	belongs to the aldehyde dehydrogenase family
FY129_25690	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY129_25700	COG3386	PFAM SMP-30 Gluconolaconase
FY129_25705	COG3622	Belongs to the hyi family
FY129_25710	COG2084	Dehydrogenase
FY129_25735	COG1940	carbohydrate kinase activity
FY129_25740	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_25750	COG1129	ABC transporter
FY129_25770	COG0583	DNA-binding transcription factor activity
FY129_25775	COG2271	Major facilitator Superfamily
FY129_25785	COG2272	Belongs to the type-B carboxylesterase lipase family
FY129_25805	COG1129	ABC transporter
FY129_25830	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY129_25840	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY129_25875	COG0583	DNA-binding transcription factor activity
FY129_25880	COG1414	Transcriptional regulator
FY129_25890	COG4948	Mandelate Racemase Muconate Lactonizing
FY129_25900	COG3842	ATPase activity
FY129_25905	COG1175	transmembrane transport
FY129_25910	COG0395	ABC-type sugar transport system, permease component
FY129_25920	COG0477	Major facilitator Superfamily
FY129_25955	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY129_25975	COG0747	negative chemotaxis
FY129_25985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_26000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_26010	COG4215	(ABC) transporter
FY129_26065	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY129_26070	COG0251	oxidation-reduction process
FY129_26075	COG3547	Transposase (IS116 IS110 IS902 family)
FY129_26110	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_26115	COG1335	isochorismatase
FY129_26125	COG1309	transcriptional regulator
FY129_26130	COG4604	ABC transporter, ATP-binding protein
FY129_26135	COG4605	iron ion homeostasis
FY129_26140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY129_26150	COG2132	Multicopper oxidase
FY129_26155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY129_26160	COG4771	TonB-dependent receptor
FY129_26195	COG1695	Transcriptional regulator
FY129_26230	COG2132	Multicopper oxidase
FY129_26265	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY129_26285	COG1192	Involved in chromosome partitioning
FY129_26290	COG1475	DNA binding
FY129_26295	COG0640	Transcriptional regulator
FY129_26345	COG0583	DNA-binding transcription factor activity
FY129_26355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY129_26360	COG1116	anion transmembrane transporter activity
FY129_26365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY129_26375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_26380	COG1028	Short-chain dehydrogenase reductase Sdr
FY129_26410	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY129_26415	COG1129	ABC transporter
FY129_26440	COG4172	Belongs to the ABC transporter superfamily
FY129_26445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_26450	COG0601	transmembrane transport
FY129_26460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_26465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_26470	COG0583	DNA-binding transcription factor activity
FY129_26480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY129_26495	COG1132	(ABC) transporter
FY129_26500	COG4172	Belongs to the ABC transporter superfamily
FY129_26505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_26515	COG0747	negative chemotaxis
FY129_26525	COG1082	Xylose isomerase domain protein TIM barrel
FY129_26595	COG1475	DNA binding
FY129_26635	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
FY129_26640	COG5489	Protein of unknown function (DUF736)
FY129_26710	COG4172	Belongs to the ABC transporter superfamily
FY129_26715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_26735	COG2072	flavoprotein involved in K transport
FY129_26740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY129_26790	COG0584	glycerophosphoryl diester phosphodiesterase
FY129_26800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_26815	COG0444	Belongs to the ABC transporter superfamily
FY129_26830	COG0747	negative chemotaxis
FY129_26850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY129_26855	COG0601	transmembrane transport
FY129_26870	COG0444	Belongs to the ABC transporter superfamily
FY129_26875	COG0747	negative chemotaxis
FY129_26885	COG2390	Transcriptional regulator
FY129_26930	COG0145	ligase activity
FY129_26940	COG0583	DNA-binding transcription factor activity
FY129_26985	COG3701	Conjugal transfer protein
FY129_26990	COG3846	protein secretion by the type IV secretion system
FY129_27000	COG5314	conjugation
FY129_27005	COG3451	type IV secretory pathway VirB4
FY129_27020	COG4962	Type ii secretion system protein e