locus-tag	class	description
CFBP5499_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFBP5499_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP5499_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFBP5499_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFBP5499_00025	COG1420	regulation of RNA biosynthetic process
CFBP5499_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFBP5499_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5499_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFBP5499_00050	COG1137	ATPase activity
CFBP5499_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CFBP5499_00065	COG0616	signal peptide processing
CFBP5499_00070	COG0776	regulation of translation
CFBP5499_00080	COG0116	Belongs to the methyltransferase superfamily
CFBP5499_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CFBP5499_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5499_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFBP5499_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFBP5499_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CFBP5499_00115	COG0728	peptidoglycan biosynthetic process
CFBP5499_00125	COG0180	Tryptophanyl-tRNA synthetase
CFBP5499_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CFBP5499_00140	COG1214	PFAM Peptidase M22, glycoprotease
CFBP5499_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP5499_00165	COG1702	phosphate starvation-inducible protein PhoH
CFBP5499_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFBP5499_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CFBP5499_00185	COG1396	sequence-specific DNA binding
CFBP5499_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFBP5499_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CFBP5499_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_00210	COG0242	peptide deformylase activity
CFBP5499_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFBP5499_00220	COG0101	tRNA pseudouridine synthase activity
CFBP5499_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_00235	COG2171	N-acyltransferase activity
CFBP5499_00245	COG0840	transmembrane signaling receptor activity
CFBP5499_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5499_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CFBP5499_00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CFBP5499_00300	COG0706	membrane insertase activity
CFBP5499_00305	COG0594	ribonuclease P activity
CFBP5499_00310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CFBP5499_00320	COG0840	transmembrane signaling receptor activity
CFBP5499_00325	COG3850	Histidine kinase
CFBP5499_00325	COG5002	protein histidine kinase activity
CFBP5499_00340	COG2226	methyltransferase
CFBP5499_00355	COG3842	ATPase activity
CFBP5499_00360	COG1175	transmembrane transport
CFBP5499_00365	COG0395	ABC-type sugar transport system, permease component
CFBP5499_00380	COG0427	acetyl-CoA hydrolase
CFBP5499_00390	COG3938	Belongs to the proline racemase family
CFBP5499_00395	COG0418	dihydroorotase activity
CFBP5499_00400	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFBP5499_00420	COG0166	Belongs to the GPI family
CFBP5499_00425	COG0318	PFAM AMP-dependent synthetase and ligase
CFBP5499_00430	COG3842	ATPase activity
CFBP5499_00435	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_00440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP5499_00445	COG4774	siderophore transport
CFBP5499_00495	COG2326	polyphosphate kinase activity
CFBP5499_00500	COG5002	protein histidine kinase activity
CFBP5499_00505	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CFBP5499_00510	COG0573	inorganic phosphate transmembrane transporter activity
CFBP5499_00520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CFBP5499_00525	COG0704	Plays a role in the regulation of phosphate uptake
CFBP5499_00530	COG0745	RESPONSE REGULATOR receiver
CFBP5499_00545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CFBP5499_00550	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFBP5499_00555	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFBP5499_00560	COG2967	ApaG domain
CFBP5499_00570	COG0717	Belongs to the dCTP deaminase family
CFBP5499_00595	COG0753	catalase activity
CFBP5499_00600	COG3685	Protein conserved in bacteria
CFBP5499_00650	COG1573	uracil-dna glycosylase
CFBP5499_00685	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CFBP5499_00735	COG0167	dihydroorotate dehydrogenase activity
CFBP5499_00750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP5499_00770	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_00775	COG1201	RNA secondary structure unwinding
CFBP5499_00795	COG0730	response to heat
CFBP5499_00810	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_00815	COG0183	Belongs to the thiolase family
CFBP5499_00820	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP5499_00820	COG1024	Enoyl-CoA hydratase
CFBP5499_00970	COG0592	DNA-directed DNA polymerase activity
CFBP5499_01100	COG0740	serine-type endopeptidase activity
CFBP5499_01200	COG2755	lipolytic protein G-D-S-L family
CFBP5499_01200	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5499_01290	COG1320	monovalent cation:proton antiporter activity
CFBP5499_01295	COG2212	antiporter activity
CFBP5499_01300	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP5499_01305	COG0651	ATP synthesis coupled electron transport
CFBP5499_01310	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP5499_01315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CFBP5499_01315	COG2111	Na H antiporter
CFBP5499_01325	COG0840	transmembrane signaling receptor activity
CFBP5499_01340	COG2198	Histidine kinase
CFBP5499_01340	COG0643	Histidine kinase
CFBP5499_01345	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CFBP5499_01350	COG2201	protein-glutamate methylesterase activity
CFBP5499_01355	COG0745	RESPONSE REGULATOR receiver
CFBP5499_01360	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CFBP5499_01370	COG1766	The M ring may be actively involved in energy transduction
CFBP5499_01375	COG2771	luxR family
CFBP5499_01385	COG2972	Histidine kinase
CFBP5499_01385	COG0840	transmembrane signaling receptor activity
CFBP5499_01390	COG0784	Response regulator, receiver
CFBP5499_01390	COG2205	protein histidine kinase activity
CFBP5499_01390	COG2198	Histidine kinase
CFBP5499_01395	COG1970	mechanosensitive ion channel activity
CFBP5499_01400	COG0436	Aminotransferase
CFBP5499_01415	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CFBP5499_01420	COG0424	maF-like protein
CFBP5499_01425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFBP5499_01435	COG5328	Belongs to the UPF0262 family
CFBP5499_01440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFBP5499_01450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFBP5499_01470	COG1431	PFAM Stem cell self-renewal protein Piwi
CFBP5499_01485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFBP5499_01495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_01510	COG0110	maltose O-acetyltransferase activity
CFBP5499_01530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CFBP5499_01565	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
CFBP5499_01575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP5499_01660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5499_01700	COG1338	Plays a role in the flagellum-specific transport system
CFBP5499_01710	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CFBP5499_01720	COG1706	bacterial-type flagellum-dependent cell motility
CFBP5499_01725	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CFBP5499_01730	COG4786	Flagellar basal body rod
CFBP5499_01735	COG1677	Flagellar hook-basal body complex protein FliE
CFBP5499_01740	COG1558	bacterial-type flagellum-dependent cell motility
CFBP5499_01745	COG1815	bacterial-type flagellum-dependent cell motility
CFBP5499_01750	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_01760	COG1157	protein secretion by the type III secretion system
CFBP5499_01765	COG4786	Flagellar basal body rod
CFBP5499_01775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CFBP5499_01780	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5499_01785	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5499_01790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFBP5499_01795	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP5499_01820	COG1360	Flagellar Motor Protein
CFBP5499_01845	COG1749	Flagellar hook protein flgE
CFBP5499_01865	COG5443	negative regulation of bacterial-type flagellum assembly
CFBP5499_01870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CFBP5499_01880	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFBP5499_01920	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP5499_01925	COG1609	Transcriptional regulator
CFBP5499_01930	COG1653	transport
CFBP5499_01935	COG1175	transmembrane transport
CFBP5499_01940	COG0395	ABC-type sugar transport system, permease component
CFBP5499_01945	COG0366	Alpha amylase catalytic
CFBP5499_01950	COG3842	ATPase activity
CFBP5499_01965	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_01970	COG0363	glucosamine-6-phosphate deaminase activity
CFBP5499_01975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFBP5499_01985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_01995	COG2081	HI0933 family
CFBP5499_02015	COG2224	Isocitrate lyase
CFBP5499_02030	COG3842	ATPase activity
CFBP5499_02035	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_02040	COG1177	transmembrane transport
CFBP5499_02050	COG2205	protein histidine kinase activity
CFBP5499_02060	COG0248	Ppx GppA phosphatase
CFBP5499_02065	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CFBP5499_02070	COG0477	Major facilitator Superfamily
CFBP5499_02110	COG0521	Mo-molybdopterin cofactor biosynthetic process
CFBP5499_02115	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFBP5499_02125	COG0142	geranyltranstransferase activity
CFBP5499_02150	COG0752	glycyl-tRNA synthetase alpha subunit
CFBP5499_02155	COG1704	LemA family
CFBP5499_02160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CFBP5499_02170	COG0751	glycine-tRNA ligase activity
CFBP5499_02180	COG1683	Conserved Protein
CFBP5499_02185	COG0840	transmembrane signaling receptor activity
CFBP5499_02195	COG0151	Belongs to the GarS family
CFBP5499_02200	COG2183	response to ionizing radiation
CFBP5499_02205	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5499_02230	COG0583	DNA-binding transcription factor activity
CFBP5499_02250	COG0306	phosphate transporter
CFBP5499_02265	COG0561	phosphatase activity
CFBP5499_02270	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_02275	COG2186	Transcriptional regulator
CFBP5499_02285	COG0583	DNA-binding transcription factor activity
CFBP5499_02290	COG0277	FAD linked oxidase domain protein
CFBP5499_02295	COG0277	FAD linked oxidase domain protein
CFBP5499_02300	COG0247	lactate metabolic process
CFBP5499_02310	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_02315	COG2818	Glycosylase
CFBP5499_02325	COG2855	membrane
CFBP5499_02330	COG0583	DNA-binding transcription factor activity
CFBP5499_02350	COG0124	histidyl-tRNA synthetase
CFBP5499_02360	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFBP5499_02365	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CFBP5499_02370	COG2259	Doxx family
CFBP5499_02385	COG0459	protein refolding
CFBP5499_02390	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFBP5499_02400	COG0196	riboflavin kinase activity
CFBP5499_02405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFBP5499_02415	COG0590	tRNA wobble adenosine to inosine editing
CFBP5499_02420	COG1187	pseudouridine synthase activity
CFBP5499_02425	COG0742	ribosomal rna small subunit methyltransferase
CFBP5499_02430	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP5499_02435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP5499_02435	COG0475	glutathione-regulated potassium exporter activity
CFBP5499_02445	COG0312	modulator of DNA gyrase
CFBP5499_02450	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_02460	COG1519	Transferase
CFBP5499_02470	COG1663	tetraacyldisaccharide 4'-kinase activity
CFBP5499_02480	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFBP5499_02485	COG0745	RESPONSE REGULATOR receiver
CFBP5499_02490	COG5001	Diguanylate cyclase
CFBP5499_02490	COG3300	MHYT domain
CFBP5499_02495	COG3386	PFAM SMP-30 Gluconolaconase
CFBP5499_02500	COG0800	Aldolase
CFBP5499_02505	COG3734	2-keto-3-deoxy-galactonokinase
CFBP5499_02510	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_02520	COG2197	response regulator
CFBP5499_02525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_02535	COG0598	Magnesium transport protein CorA
CFBP5499_02540	COG3158	transport of potassium into the cell
CFBP5499_02555	COG0356	it plays a direct role in the translocation of protons across the membrane
CFBP5499_02565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP5499_02570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFBP5499_02585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFBP5499_02605	COG0009	L-threonylcarbamoyladenylate synthase
CFBP5499_02615	COG4638	Rieske (2fe-2S)
CFBP5499_02640	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_02655	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFBP5499_02660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CFBP5499_02665	COG0840	transmembrane signaling receptor activity
CFBP5499_02675	COG1522	sequence-specific DNA binding
CFBP5499_02705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFBP5499_02710	COG1741	Belongs to the pirin family
CFBP5499_02715	COG1722	exodeoxyribonuclease VII activity
CFBP5499_02720	COG0123	including yeast histone deacetylase and acetoin utilization protein
CFBP5499_02725	COG1268	BioY protein
CFBP5499_02730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFBP5499_02735	COG1122	ATPase activity
CFBP5499_02740	COG3214	Protein conserved in bacteria
CFBP5499_02750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFBP5499_02770	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP5499_02785	COG0259	pyridoxamine-phosphate oxidase activity
CFBP5499_02800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_02810	COG0312	modulator of DNA gyrase
CFBP5499_02830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5499_02835	COG0109	protoheme IX farnesyltransferase activity
CFBP5499_02845	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CFBP5499_02860	COG3346	SURF1 family
CFBP5499_02865	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFBP5499_02870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFBP5499_02875	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP5499_02890	COG0678	peroxiredoxin activity
CFBP5499_02890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CFBP5499_02900	COG1678	Uncharacterized ACR, COG1678
CFBP5499_02915	COG5001	Diguanylate cyclase
CFBP5499_02915	COG3300	MHYT domain
CFBP5499_02920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5499_02925	COG0612	Peptidase, M16
CFBP5499_02940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_02945	COG1802	Transcriptional regulator
CFBP5499_02965	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CFBP5499_02975	COG3609	addiction module antidote protein, CC2985 family
CFBP5499_02990	COG1194	a g-specific adenine glycosylase
CFBP5499_03005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CFBP5499_03010	COG1196	nuclear chromosome segregation
CFBP5499_03020	COG2514	catechol 2,3-dioxygenase activity
CFBP5499_03025	COG0574	Belongs to the PEP-utilizing enzyme family
CFBP5499_03025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFBP5499_03070	COG0579	oxidoreductase
CFBP5499_03095	COG2895	sulfate adenylyltransferase (ATP) activity
CFBP5499_03100	COG0175	sulfate reduction
CFBP5499_03105	COG0175	sulfate reduction
CFBP5499_03110	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_03115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CFBP5499_03120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CFBP5499_03125	COG4208	sulfate ABC transporter
CFBP5499_03130	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5499_03145	COG2200	EAL domain
CFBP5499_03145	COG2199	diguanylate cyclase activity
CFBP5499_03145	COG2203	Gaf domain
CFBP5499_03155	COG1309	transcriptional regulator
CFBP5499_03160	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_03170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CFBP5499_03215	COG0477	Major facilitator Superfamily
CFBP5499_03225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CFBP5499_03225	COG1793	dna ligase
CFBP5499_03240	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_03245	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_03255	COG1846	Transcriptional regulator
CFBP5499_03260	COG1764	response to oxidative stress
CFBP5499_03275	COG0488	(ABC) transporter
CFBP5499_03285	COG1846	Transcriptional regulator
CFBP5499_03305	COG0583	DNA-binding transcription factor activity
CFBP5499_03310	COG4221	oxidoreductase activity
CFBP5499_03320	COG0433	COG0433 Predicted ATPase
CFBP5499_03335	COG1733	regulation of RNA biosynthetic process
CFBP5499_03340	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
CFBP5499_03350	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_03355	COG0656	L-ascorbic acid biosynthetic process
CFBP5499_03360	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_03365	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_03370	COG0840	transmembrane signaling receptor activity
CFBP5499_03375	COG0583	DNA-binding transcription factor activity
CFBP5499_03390	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP5499_03400	COG2378	regulation of single-species biofilm formation
CFBP5499_03410	COG3909	cytochrome
CFBP5499_03415	COG2010	Cytochrome c
CFBP5499_03450	COG0789	Transcriptional regulator
CFBP5499_03475	COG4175	Glycine betaine
CFBP5499_03475	COG0517	IMP dehydrogenase activity
CFBP5499_03480	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_03510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_03520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5499_03520	COG2169	Transcriptional regulator
CFBP5499_03530	COG2514	catechol 2,3-dioxygenase activity
CFBP5499_03550	COG1272	protein, Hemolysin III
CFBP5499_03560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP5499_03570	COG2111	Na H antiporter
CFBP5499_03575	COG1006	Multisubunit Na H antiporter MnhC subunit
CFBP5499_03585	COG1863	multisubunit Na H antiporter MnhE subunit
CFBP5499_03590	COG2212	antiporter activity
CFBP5499_03595	COG1320	monovalent cation:proton antiporter activity
CFBP5499_03600	COG4957	zinc ion binding
CFBP5499_03615	COG2166	iron-sulfur cluster assembly
CFBP5499_03625	COG2205	protein histidine kinase activity
CFBP5499_03680	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5499_03685	COG2983	Belongs to the UPF0260 family
CFBP5499_03730	COG2814	Major facilitator Superfamily
CFBP5499_03740	COG1621	beta-fructofuranosidase activity
CFBP5499_03745	COG3920	Histidine kinase
CFBP5499_03745	COG2202	Pas domain
CFBP5499_03750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CFBP5499_03800	COG4695	Portal protein
CFBP5499_03900	COG0745	RESPONSE REGULATOR receiver
CFBP5499_03905	COG2205	protein histidine kinase activity
CFBP5499_03915	COG4235	cytochrome complex assembly
CFBP5499_03920	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CFBP5499_03925	COG1138	Cytochrome C-type biogenesis protein
CFBP5499_03930	COG3088	subunit of a heme lyase
CFBP5499_03935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP5499_03940	COG0745	RESPONSE REGULATOR receiver
CFBP5499_03945	COG2205	protein histidine kinase activity
CFBP5499_03950	COG3011	Protein conserved in bacteria
CFBP5499_03960	COG3713	MltA-interacting MipA family protein
CFBP5499_03965	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CFBP5499_03975	COG2205	protein histidine kinase activity
CFBP5499_03975	COG2202	Pas domain
CFBP5499_03985	COG0308	aminopeptidase N
CFBP5499_03990	COG0697	spore germination
CFBP5499_04010	COG0443	Heat shock 70 kDa protein
CFBP5499_04015	COG2199	diguanylate cyclase activity
CFBP5499_04015	COG2203	Gaf domain
CFBP5499_04020	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_04040	COG1733	regulation of RNA biosynthetic process
CFBP5499_04055	COG0604	alcohol dehydrogenase
CFBP5499_04060	COG1733	regulation of RNA biosynthetic process
CFBP5499_04065	COG1968	undecaprenyl-diphosphatase activity
CFBP5499_04070	COG2239	Acts as a magnesium transporter
CFBP5499_04075	COG2814	Major facilitator Superfamily
CFBP5499_04105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP5499_04130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP5499_04135	COG2132	Multicopper oxidase
CFBP5499_04200	COG1802	Transcriptional regulator
CFBP5499_04200	COG4626	Terminase
CFBP5499_04285	COG0582	viral genome integration into host DNA
CFBP5499_04310	COG0741	lytic transglycosylase activity
CFBP5499_04320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_04325	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFBP5499_04335	COG0840	transmembrane signaling receptor activity
CFBP5499_04345	COG1758	RNA polymerase activity
CFBP5499_04370	COG0736	holo-[acyl-carrier-protein] synthase activity
CFBP5499_04375	COG0681	Belongs to the peptidase S26 family
CFBP5499_04380	COG0571	ribonuclease III activity
CFBP5499_04385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFBP5499_04390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5499_04395	COG0784	Response regulator, receiver
CFBP5499_04400	COG1381	Involved in DNA repair and RecF pathway recombination
CFBP5499_04410	COG2226	methyltransferase
CFBP5499_04420	COG1418	mRNA catabolic process
CFBP5499_04430	COG0346	lactoylglutathione lyase activity
CFBP5499_04440	COG1116	anion transmembrane transporter activity
CFBP5499_04445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_04450	COG3443	Belongs to the bacterial solute-binding protein 9 family
CFBP5499_04455	COG0668	transmembrane transport
CFBP5499_04465	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CFBP5499_04495	COG1742	UPF0060 membrane protein
CFBP5499_04505	COG0745	RESPONSE REGULATOR receiver
CFBP5499_04505	COG3706	GGDEF domain
CFBP5499_04515	COG1183	phosphatidylcholine synthase activity
CFBP5499_04520	COG0688	phosphatidylethanolamine metabolic process
CFBP5499_04525	COG5265	(ABC) transporter
CFBP5499_04565	COG2852	Protein conserved in bacteria
CFBP5499_04575	COG0215	cysteine-tRNA ligase activity
CFBP5499_04580	COG4221	oxidoreductase activity
CFBP5499_04585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP5499_04590	COG1286	toxin biosynthetic process
CFBP5499_04610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP5499_04620	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CFBP5499_04630	COG0305	Participates in initiation and elongation during chromosome replication
CFBP5499_04655	COG0359	binds to the 23S rRNA
CFBP5499_04665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFBP5499_04670	COG0360	Binds together with S18 to 16S ribosomal RNA
CFBP5499_04685	COG0667	Aldo Keto reductase
CFBP5499_04690	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CFBP5499_04700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_04705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_04715	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFBP5499_04720	COG1561	YicC-like family, N-terminal region
CFBP5499_04725	COG0194	GDP metabolic process
CFBP5499_04740	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP5499_04745	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5499_04755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CFBP5499_04770	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP5499_04785	COG1716	ATPase activity
CFBP5499_04785	COG5001	Diguanylate cyclase
CFBP5499_04790	COG0488	(ABC) transporter
CFBP5499_04795	COG3706	GGDEF domain
CFBP5499_04805	COG0105	UTP biosynthetic process
CFBP5499_04825	COG0314	molybdopterin synthase activity
CFBP5499_04830	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CFBP5499_04835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFBP5499_04840	COG0322	excinuclease ABC activity
CFBP5499_04845	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_04855	COG0625	glutathione transferase activity
CFBP5499_04870	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CFBP5499_04875	COG0243	molybdopterin cofactor binding
CFBP5499_04900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFBP5499_04905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CFBP5499_04915	COG0628	permease
CFBP5499_04925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CFBP5499_04930	COG0248	Ppx GppA phosphatase
CFBP5499_04945	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CFBP5499_04955	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CFBP5499_04960	COG0477	Major facilitator Superfamily
CFBP5499_04965	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFBP5499_04975	COG4452	Inner membrane protein CreD
CFBP5499_04980	COG0659	secondary active sulfate transmembrane transporter activity
CFBP5499_04990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP5499_04995	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CFBP5499_05005	COG0113	porphobilinogen synthase activity
CFBP5499_05030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP5499_05035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFBP5499_05040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5499_05040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFBP5499_05050	COG2249	NAD(P)H dehydrogenase (quinone) activity
CFBP5499_05055	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_05060	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CFBP5499_05065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP5499_05070	COG2814	Major facilitator Superfamily
CFBP5499_05075	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CFBP5499_05095	COG0416	fatty acid biosynthetic process
CFBP5499_05100	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP5499_05105	COG0776	regulation of translation
CFBP5499_05145	COG0601	transmembrane transport
CFBP5499_05150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_05155	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_05165	COG0747	negative chemotaxis
CFBP5499_05175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CFBP5499_05180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP5499_05190	COG0745	RESPONSE REGULATOR receiver
CFBP5499_05190	COG3706	GGDEF domain
CFBP5499_05195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFBP5499_05200	COG0583	DNA-binding transcription factor activity
CFBP5499_05205	COG0737	Belongs to the 5'-nucleotidase family
CFBP5499_05230	COG2897	thiosulfate sulfurtransferase activity
CFBP5499_05245	COG0415	Belongs to the DNA photolyase family
CFBP5499_05255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5499_05290	COG3932	Exopolysaccharide synthesis, ExoD
CFBP5499_05310	COG4139	cobalamin transport
CFBP5499_05315	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP5499_05320	COG3794	PFAM blue (type 1) copper domain protein
CFBP5499_05390	COG1612	heme a metabolic process
CFBP5499_05400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFBP5499_05405	COG0010	Belongs to the arginase family
CFBP5499_05410	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CFBP5499_05415	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFBP5499_05430	COG1832	CoA-binding protein
CFBP5499_05445	COG2124	cytochrome p450
CFBP5499_05450	COG2199	diguanylate cyclase activity
CFBP5499_05455	COG0740	serine-type endopeptidase activity
CFBP5499_05460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFBP5499_05470	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFBP5499_05480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5499_05505	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_05510	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_05515	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_05525	COG0649	NAD binding
CFBP5499_05535	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CFBP5499_05540	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CFBP5499_05550	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CFBP5499_05555	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CFBP5499_05565	COG0713	ATP synthesis coupled electron transport
CFBP5499_05580	COG1007	ATP synthesis coupled electron transport
CFBP5499_05585	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CFBP5499_05585	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CFBP5499_05605	COG0442	prolyl-tRNA aminoacylation
CFBP5499_05615	COG1136	(ABC) transporter
CFBP5499_05625	COG0587	DNA-directed DNA polymerase activity
CFBP5499_05635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5499_05655	COG0784	Response regulator, receiver
CFBP5499_05660	COG0745	RESPONSE REGULATOR receiver
CFBP5499_05660	COG3706	GGDEF domain
CFBP5499_05670	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CFBP5499_05675	COG0477	Major facilitator Superfamily
CFBP5499_05690	COG0557	exoribonuclease II activity
CFBP5499_05695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFBP5499_05705	COG0758	DNA mediated transformation
CFBP5499_05710	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CFBP5499_05720	COG0540	Belongs to the ATCase OTCase family
CFBP5499_05730	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_05735	COG0456	acetyltransferase
CFBP5499_05750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFBP5499_05755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CFBP5499_05760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP5499_05765	COG0154	amidase activity
CFBP5499_05770	COG3811	Belongs to the UPF0386 family
CFBP5499_05785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFBP5499_05795	COG0456	acetyltransferase
CFBP5499_05810	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CFBP5499_05815	COG0439	Biotin carboxylase
CFBP5499_05820	COG0511	ligase activity, forming carbon-carbon bonds
CFBP5499_05825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP5499_05835	COG0436	Aminotransferase
CFBP5499_05855	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_05860	COG1530	ribonuclease E activity
CFBP5499_05875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5499_05895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFBP5499_05900	COG0384	phenazine biosynthesis protein PhzF
CFBP5499_05915	COG0633	Ferredoxin
CFBP5499_05925	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFBP5499_05930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFBP5499_05935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFBP5499_05945	COG3768	UPF0283 membrane protein
CFBP5499_05950	COG3106	COG3106 Predicted ATPase
CFBP5499_05960	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CFBP5499_05980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP5499_06020	COG0537	adenosine 5'-monophosphoramidase activity
CFBP5499_06045	COG0052	Belongs to the universal ribosomal protein uS2 family
CFBP5499_06050	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFBP5499_06055	COG0528	UMP kinase activity
CFBP5499_06060	COG0233	cytoplasmic translational termination
CFBP5499_06065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFBP5499_06070	COG0575	Belongs to the CDS family
CFBP5499_06075	COG0750	zinc metalloprotease
CFBP5499_06080	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP5499_06085	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5499_06090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5499_06095	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5499_06100	COG3494	Protein of unknown function (DUF1009)
CFBP5499_06105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CFBP5499_06110	COG2186	Transcriptional regulator
CFBP5499_06120	COG0765	amino acid transport
CFBP5499_06125	COG0765	amino acid transport
CFBP5499_06135	COG0372	Belongs to the citrate synthase family
CFBP5499_06150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFBP5499_06155	COG4598	ABC transporter
CFBP5499_06160	COG0765	amino acid transport
CFBP5499_06165	COG0765	amino acid transport
CFBP5499_06170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_06175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_06185	COG0395	ABC-type sugar transport system, permease component
CFBP5499_06195	COG2182	Extracellular solute-binding protein
CFBP5499_06205	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_06210	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_06215	COG1063	alcohol dehydrogenase
CFBP5499_06220	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP5499_06230	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CFBP5499_06235	COG0148	phosphopyruvate hydratase activity
CFBP5499_06245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CFBP5499_06250	COG0022	dehydrogenase e1 component
CFBP5499_06250	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5499_06255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5499_06265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP5499_06275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFBP5499_06280	COG0697	spore germination
CFBP5499_06300	COG2867	negative regulation of translational initiation
CFBP5499_06305	COG1546	Belongs to the CinA family
CFBP5499_06310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CFBP5499_06310	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CFBP5499_06320	COG3852	Histidine kinase
CFBP5499_06325	COG2204	response regulator
CFBP5499_06330	COG5000	phosphorelay sensor kinase activity
CFBP5499_06335	COG2204	response regulator
CFBP5499_06340	COG0569	domain protein
CFBP5499_06345	COG1923	regulation of RNA biosynthetic process
CFBP5499_06350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFBP5499_06355	COG3956	TIGRFAM MazG family protein
CFBP5499_06370	COG1648	precorrin-2 dehydrogenase activity
CFBP5499_06370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5499_06410	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP5499_06410	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFBP5499_06415	COG0509	glycine decarboxylation via glycine cleavage system
CFBP5499_06420	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_06445	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP5499_06450	COG0564	pseudouridine synthase activity
CFBP5499_06470	COG0251	oxidation-reduction process
CFBP5499_06475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CFBP5499_06485	COG1671	Belongs to the UPF0178 family
CFBP5499_06495	COG0450	alkyl hydroperoxide reductase
CFBP5499_06565	COG0431	NADPH-dependent FMN reductase
CFBP5499_06575	COG0798	PFAM Bile acid sodium symporter
CFBP5499_06590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CFBP5499_06590	COG0321	lipoyl(octanoyl) transferase activity
CFBP5499_06595	COG0084	hydrolase, TatD family'
CFBP5499_06600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5499_06610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP5499_06655	COG4626	Terminase
CFBP5499_06655	COG1802	Transcriptional regulator
CFBP5499_06730	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFBP5499_06735	COG2095	MarC family integral membrane protein
CFBP5499_06745	COG0629	single-stranded DNA binding
CFBP5499_06750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFBP5499_06765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFBP5499_06785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5499_06790	COG1121	(ABC) transporter
CFBP5499_06795	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CFBP5499_06800	COG1609	Transcriptional regulator
CFBP5499_06810	COG0667	Aldo Keto reductase
CFBP5499_06820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFBP5499_06900	COG2239	Acts as a magnesium transporter
CFBP5499_06905	COG0243	molybdopterin cofactor binding
CFBP5499_06915	COG0242	peptide deformylase activity
CFBP5499_06945	COG0321	lipoyl(octanoyl) transferase activity
CFBP5499_06950	COG1064	alcohol dehydrogenase
CFBP5499_06995	COG1309	transcriptional regulator
CFBP5499_07000	COG2124	cytochrome p450
CFBP5499_07025	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_07030	COG0626	cystathionine gamma-synthase activity
CFBP5499_07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_07040	COG4597	amino acid ABC transporter
CFBP5499_07045	COG0765	amino acid transport
CFBP5499_07050	COG1126	abc transporter atp-binding protein
CFBP5499_07075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CFBP5499_07090	COG0436	Aminotransferase
CFBP5499_07120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_07135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5499_07140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_07145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CFBP5499_07160	COG3243	poly(R)-hydroxyalkanoic acid synthase
CFBP5499_07165	COG1489	DNA binding
CFBP5499_07170	COG0024	Methionine aminopeptidase
CFBP5499_07175	COG2003	Belongs to the UPF0758 family
CFBP5499_07190	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CFBP5499_07205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFBP5499_07210	COG0546	phosphoglycolate phosphatase activity
CFBP5499_07220	COG0114	fumarate hydratase activity
CFBP5499_07225	COG0504	CTP synthase activity
CFBP5499_07235	COG0149	triose-phosphate isomerase activity
CFBP5499_07245	COG0187	DNA topoisomerase II activity
CFBP5499_07250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP5499_07265	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CFBP5499_07265	COG3264	Mechanosensitive ion channel
CFBP5499_07330	COG1127	ABC transporter
CFBP5499_07335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CFBP5499_07340	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_07350	COG0281	malic enzyme
CFBP5499_07350	COG0280	phosphate acetyltransferase
CFBP5499_07360	COG0778	Nitroreductase
CFBP5499_07365	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5499_07380	COG1368	sulfuric ester hydrolase activity
CFBP5499_07410	COG0544	peptidyl-prolyl cis-trans isomerase activity
CFBP5499_07435	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFBP5499_07440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP5499_07460	COG0019	diaminopimelate decarboxylase activity
CFBP5499_07480	COG0343	queuine tRNA-ribosyltransferase activity
CFBP5499_07485	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFBP5499_07490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFBP5499_07495	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFBP5499_07500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFBP5499_07525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP5499_07530	COG0134	indole-3-glycerol-phosphate synthase activity
CFBP5499_07535	COG0315	cyclic pyranopterin monophosphate synthase activity
CFBP5499_07540	COG0303	'Molybdopterin
CFBP5499_07545	COG3706	GGDEF domain
CFBP5499_07555	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CFBP5499_07555	COG0475	glutathione-regulated potassium exporter activity
CFBP5499_07570	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFBP5499_07575	COG0697	spore germination
CFBP5499_07580	COG2814	Major facilitator Superfamily
CFBP5499_07585	COG0746	molybdenum cofactor guanylyltransferase activity
CFBP5499_07590	COG1763	Mo-molybdopterin cofactor biosynthetic process
CFBP5499_07595	COG0739	heme binding
CFBP5499_07600	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP5499_07605	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CFBP5499_07610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP5499_07615	COG0805	protein transport
CFBP5499_07620	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP5499_07625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFBP5499_07630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP5499_07635	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFBP5499_07640	COG1472	Belongs to the glycosyl hydrolase 3 family
CFBP5499_07650	COG0018	arginyl-trna synthetase
CFBP5499_07655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CFBP5499_07660	COG0316	Belongs to the HesB IscA family
CFBP5499_07670	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CFBP5499_07685	COG0525	valine-tRNA ligase activity
CFBP5499_07695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CFBP5499_07740	COG0655	NAD(P)H dehydrogenase (quinone) activity
CFBP5499_07745	COG1058	Belongs to the CinA family
CFBP5499_07745	COG1546	Belongs to the CinA family
CFBP5499_07750	COG0589	response to stress
CFBP5499_07755	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CFBP5499_07760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFBP5499_07775	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP5499_07785	COG1132	(ABC) transporter
CFBP5499_07790	COG0628	permease
CFBP5499_07825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFBP5499_07835	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CFBP5499_07845	COG0302	gtp cyclohydrolase
CFBP5499_07850	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFBP5499_07855	COG1752	Esterase of the alpha-beta hydrolase superfamily
CFBP5499_07860	COG0517	IMP dehydrogenase activity
CFBP5499_07860	COG0516	GMP reductase activity
CFBP5499_07900	COG1760	l-serine dehydratase
CFBP5499_07935	COG0583	DNA-binding transcription factor activity
CFBP5499_07950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CFBP5499_07950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFBP5499_07955	COG0347	Belongs to the P(II) protein family
CFBP5499_07960	COG0174	glutamine synthetase
CFBP5499_07990	COG0697	spore germination
CFBP5499_08005	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFBP5499_08015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFBP5499_08045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5499_08055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP5499_08060	COG2186	Transcriptional regulator
CFBP5499_08070	COG1079	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_08080	COG1129	ABC transporter
CFBP5499_08085	COG1183	phosphatidylcholine synthase activity
CFBP5499_08095	COG0679	Auxin Efflux Carrier
CFBP5499_08100	COG0785	Cytochrome C biogenesis protein
CFBP5499_08130	COG1278	Cold shock
CFBP5499_08190	COG1876	peptidase activity
CFBP5499_08290	COG1136	(ABC) transporter
CFBP5499_08290	COG0577	efflux transmembrane transporter activity
CFBP5499_08295	COG1136	(ABC) transporter
CFBP5499_08295	COG0577	efflux transmembrane transporter activity
CFBP5499_08310	COG2151	metal-sulfur cluster biosynthetic enzyme
CFBP5499_08315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFBP5499_08320	COG0719	Fe-S assembly protein
CFBP5499_08325	COG0396	ATPase activity
CFBP5499_08335	COG0719	Fe-S assembly protein
CFBP5499_08340	COG1104	cysteine desulfurase activity
CFBP5499_08345	COG2945	thiolester hydrolase activity
CFBP5499_08355	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CFBP5499_08360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFBP5499_08370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFBP5499_08375	COG0739	heme binding
CFBP5499_08380	COG0513	Belongs to the DEAD box helicase family
CFBP5499_08420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFBP5499_08430	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP5499_08435	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP5499_08440	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP5499_08455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_08460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFBP5499_08485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CFBP5499_08490	COG2814	Major facilitator Superfamily
CFBP5499_08495	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_08500	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_08505	COG0037	tRNA processing
CFBP5499_08510	COG2066	Belongs to the glutaminase family
CFBP5499_08515	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFBP5499_08520	COG0861	Integral membrane protein TerC family
CFBP5499_08535	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_08550	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CFBP5499_08555	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CFBP5499_08565	COG0538	isocitrate dehydrogenase activity
CFBP5499_08590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFBP5499_08595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFBP5499_08600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_08605	COG2313	pseudouridylate synthase activity
CFBP5499_08610	COG3385	transposase activity
CFBP5499_08625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_08630	COG4215	(ABC) transporter
CFBP5499_08640	COG5425	PFAM Usg family protein
CFBP5499_08650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_08655	COG1522	sequence-specific DNA binding
CFBP5499_08660	COG1573	uracil-dna glycosylase
CFBP5499_08670	COG2205	protein histidine kinase activity
CFBP5499_08670	COG2202	Pas domain
CFBP5499_08680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CFBP5499_08685	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CFBP5499_08700	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFBP5499_08710	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_08715	COG1129	ABC transporter
CFBP5499_08720	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_08725	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_08730	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP5499_08735	COG3958	Transketolase
CFBP5499_08740	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP5499_08745	COG2390	Transcriptional regulator
CFBP5499_08755	COG0842	Transport permease protein
CFBP5499_08760	COG1131	(ABC) transporter
CFBP5499_08780	COG0840	transmembrane signaling receptor activity
CFBP5499_08780	COG0840	transmembrane signaling receptor activity
CFBP5499_08790	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CFBP5499_08795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFBP5499_08810	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_08815	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP5499_08820	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CFBP5499_08830	COG0203	ribosomal protein L17
CFBP5499_08835	COG0202	RNA polymerase activity
CFBP5499_08840	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFBP5499_08845	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFBP5499_08850	COG0563	adenylate kinase activity
CFBP5499_08855	COG0201	protein transport
CFBP5499_08860	COG0200	Binds to the 23S rRNA
CFBP5499_08865	COG1841	ribosomal large subunit assembly
CFBP5499_08870	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFBP5499_08875	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFBP5499_08880	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFBP5499_08885	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFBP5499_08890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFBP5499_08895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFBP5499_08900	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFBP5499_08905	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFBP5499_08910	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFBP5499_08915	COG0255	Belongs to the universal ribosomal protein uL29 family
CFBP5499_08920	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFBP5499_08925	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFBP5499_08930	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFBP5499_08935	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFBP5499_08940	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFBP5499_08945	COG0089	rRNA binding
CFBP5499_08950	COG0088	Forms part of the polypeptide exit tunnel
CFBP5499_08955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFBP5499_08960	COG0051	transcription antitermination factor activity, RNA binding
CFBP5499_08965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP5499_08970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFBP5499_08975	COG0049	tRNA binding
CFBP5499_08980	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFBP5499_09000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFBP5499_09005	COG0085	RNA polymerase activity
CFBP5499_09010	COG0222	ribosome binding
CFBP5499_09015	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFBP5499_09020	COG0081	regulation of translation
CFBP5499_09025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFBP5499_09050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFBP5499_09055	COG0861	Integral membrane protein TerC family
CFBP5499_09070	COG3895	Periplasmic Protein
CFBP5499_09105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFBP5499_09110	COG1607	acyl-coa hydrolase
CFBP5499_09135	COG2910	NAD(P)H-binding
CFBP5499_09140	COG1733	regulation of RNA biosynthetic process
CFBP5499_09150	COG0556	nucleotide-excision repair
CFBP5499_09180	COG0484	heat shock protein binding
CFBP5499_09195	COG3706	GGDEF domain
CFBP5499_09205	COG3842	ATPase activity
CFBP5499_09210	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_09215	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_09225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_09230	COG4154	Belongs to the RbsD FucU family
CFBP5499_09240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFBP5499_09250	COG2207	Transcriptional regulator
CFBP5499_09255	COG1064	alcohol dehydrogenase
CFBP5499_09260	COG1252	NADH dehydrogenase
CFBP5499_09265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CFBP5499_09270	COG2197	response regulator
CFBP5499_09275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5499_09280	COG0702	epimerase
CFBP5499_09320	COG0656	L-ascorbic acid biosynthetic process
CFBP5499_09335	COG0440	acetolactate synthase activity
CFBP5499_09340	COG0028	Belongs to the TPP enzyme family
CFBP5499_09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFBP5499_09355	COG0560	Phosphoserine phosphatase
CFBP5499_09375	COG0330	HflC and HflK could
CFBP5499_09380	COG0330	HflC and HflK could
CFBP5499_09390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFBP5499_09425	COG0277	FAD linked oxidase domain protein
CFBP5499_09430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5499_09465	COG0596	Alpha beta hydrolase
CFBP5499_09485	COG1335	isochorismatase
CFBP5499_09515	COG2264	protein methyltransferase activity
CFBP5499_09520	COG1999	signal sequence binding
CFBP5499_09530	COG0835	chemotaxis
CFBP5499_09545	COG0583	DNA-binding transcription factor activity
CFBP5499_09555	COG1247	-acetyltransferase
CFBP5499_09565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFBP5499_09580	COG0497	DNA recombination
CFBP5499_09585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CFBP5499_09595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5499_09600	COG0849	cell division
CFBP5499_09605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CFBP5499_09610	COG1181	Belongs to the D-alanine--D-alanine ligase family
CFBP5499_09615	COG0477	Major facilitator Superfamily
CFBP5499_09620	COG3300	MHYT domain
CFBP5499_09620	COG5001	Diguanylate cyclase
CFBP5499_09625	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CFBP5499_09630	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CFBP5499_09635	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP5499_09645	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFBP5499_09650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFBP5499_09660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFBP5499_09675	COG0275	rRNA processing
CFBP5499_09680	COG2001	Belongs to the MraZ family
CFBP5499_09690	COG0300	oxidoreductase activity
CFBP5499_09695	COG1733	regulation of RNA biosynthetic process
CFBP5499_09720	COG3023	N-Acetylmuramoyl-L-alanine amidase
CFBP5499_09725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CFBP5499_09750	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_09780	COG2267	carboxylic ester hydrolase activity
CFBP5499_09785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CFBP5499_09800	COG0251	oxidation-reduction process
CFBP5499_09815	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_09820	COG2814	Major facilitator Superfamily
CFBP5499_09825	COG1309	transcriptional regulator
CFBP5499_09845	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_09850	COG0174	glutamine synthetase
CFBP5499_09855	COG0531	amino acid
CFBP5499_09865	COG1737	Transcriptional regulator
CFBP5499_09875	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_09880	COG1178	ABC-type Fe3 transport system permease component
CFBP5499_09890	COG3842	ATPase activity
CFBP5499_09950	COG2968	Membrane
CFBP5499_09960	COG0432	Pfam Uncharacterised protein family UPF0047
CFBP5499_09975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP5499_09980	COG0358	DNA primase activity
CFBP5499_09990	COG0505	Belongs to the CarA family
CFBP5499_09995	COG0534	Mate efflux family protein
CFBP5499_10010	COG2321	neutral zinc metallopeptidase
CFBP5499_10025	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CFBP5499_10035	COG3706	GGDEF domain
CFBP5499_10050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CFBP5499_10060	COG1522	sequence-specific DNA binding
CFBP5499_10065	COG0492	ferredoxin-NADP+ reductase activity
CFBP5499_10070	COG0583	DNA-binding transcription factor activity
CFBP5499_10080	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_10115	COG0387	Pfam Sodium calcium exchanger
CFBP5499_10125	COG2200	EAL domain
CFBP5499_10125	COG2199	diguanylate cyclase activity
CFBP5499_10140	COG1278	Cold shock
CFBP5499_10145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5499_10160	COG1846	Transcriptional regulator
CFBP5499_10165	COG0745	RESPONSE REGULATOR receiver
CFBP5499_10170	COG2205	protein histidine kinase activity
CFBP5499_10175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5499_10195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFBP5499_10220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFBP5499_10230	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFBP5499_10245	COG0840	transmembrane signaling receptor activity
CFBP5499_10250	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_10260	COG5001	Diguanylate cyclase
CFBP5499_10260	COG3300	MHYT domain
CFBP5499_10265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFBP5499_10270	COG5001	Diguanylate cyclase
CFBP5499_10280	COG0193	aminoacyl-tRNA hydrolase activity
CFBP5499_10290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CFBP5499_10295	COG0012	GTP binding
CFBP5499_10310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFBP5499_10320	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CFBP5499_10320	COG2857	Cytochrome c1
CFBP5499_10340	COG1132	(ABC) transporter
CFBP5499_10345	COG1132	(ABC) transporter
CFBP5499_10350	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CFBP5499_10365	COG0408	coproporphyrinogen oxidase activity
CFBP5499_10380	COG0617	tRNA 3'-terminal CCA addition
CFBP5499_10395	COG0714	Associated with various cellular activities
CFBP5499_10415	COG0454	-acetyltransferase
CFBP5499_10420	COG0477	Major facilitator Superfamily
CFBP5499_10430	COG0435	Glutathione S-transferase
CFBP5499_10445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFBP5499_10460	COG3135	benzoate transporter
CFBP5499_10470	COG1595	DNA-templated transcription, initiation
CFBP5499_10480	COG0740	serine-type endopeptidase activity
CFBP5499_10495	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFBP5499_10500	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFBP5499_10530	COG4175	Glycine betaine
CFBP5499_10545	COG1435	thymidine kinase activity
CFBP5499_10580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFBP5499_10580	COG0512	Glutamine amidotransferase of anthranilate synthase
CFBP5499_10595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_10610	COG0366	Alpha amylase catalytic
CFBP5499_10615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_10635	COG1160	GTP binding
CFBP5499_10655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CFBP5499_10665	COG0024	Methionine aminopeptidase
CFBP5499_10675	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_10685	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP5499_10695	COG0583	DNA-binding transcription factor activity
CFBP5499_10710	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5499_10720	COG1304	FMN binding
CFBP5499_10730	COG1309	transcriptional regulator
CFBP5499_10735	COG1686	Belongs to the peptidase S11 family
CFBP5499_10745	COG2351	hydroxyisourate hydrolase activity
CFBP5499_10750	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CFBP5499_10775	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5499_10785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_10785	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CFBP5499_10790	COG5002	protein histidine kinase activity
CFBP5499_10790	COG2205	protein histidine kinase activity
CFBP5499_10790	COG0784	Response regulator, receiver
CFBP5499_10795	COG0513	Belongs to the DEAD box helicase family
CFBP5499_10805	COG2259	Doxx family
CFBP5499_10810	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_10815	COG0697	spore germination
CFBP5499_10820	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP5499_10830	COG1305	Transglutaminase-like
CFBP5499_10855	COG4214	carbohydrate transport
CFBP5499_10860	COG1129	ABC transporter
CFBP5499_10865	COG4213	ABC transporter substrate-binding protein
CFBP5499_10915	COG0840	transmembrane signaling receptor activity
CFBP5499_10920	COG0840	transmembrane signaling receptor activity
CFBP5499_10925	COG2814	Major facilitator Superfamily
CFBP5499_10940	COG4215	(ABC) transporter
CFBP5499_10980	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_11015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP5499_11020	COG2346	COG2346, Truncated hemoglobins
CFBP5499_11040	COG1309	transcriptional regulator
CFBP5499_11055	COG0494	nUDIX hydrolase
CFBP5499_11070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_11075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_11100	COG1234	tRNA 3'-trailer cleavage
CFBP5499_11105	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFBP5499_11110	COG0830	nickel cation binding
CFBP5499_11115	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CFBP5499_11120	COG3385	transposase activity
CFBP5499_11135	COG0804	urea catabolic process
CFBP5499_11145	COG3755	Protein conserved in bacteria
CFBP5499_11155	COG0832	Belongs to the urease beta subunit family
CFBP5499_11160	COG3813	Protein conserved in bacteria
CFBP5499_11165	COG0831	urea catabolic process
CFBP5499_11170	COG0829	nickel cation binding
CFBP5499_11195	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_11210	COG0174	glutamine synthetase
CFBP5499_11215	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_11220	COG5002	protein histidine kinase activity
CFBP5499_11220	COG2198	Histidine kinase
CFBP5499_11220	COG0784	Response regulator, receiver
CFBP5499_11250	COG0411	ABC transporter
CFBP5499_11265	COG1218	3'(2'),5'-bisphosphate nucleotidase
CFBP5499_11345	COG0564	pseudouridine synthase activity
CFBP5499_11355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFBP5499_11370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFBP5499_11410	COG0346	lactoylglutathione lyase activity
CFBP5499_11420	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFBP5499_11430	COG2832	Protein of unknown function (DUF454)
CFBP5499_11435	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CFBP5499_11440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_11445	COG4558	Periplasmic binding protein
CFBP5499_11455	COG3721	Heme iron utilization protein
CFBP5499_11475	COG3657	addiction module killer protein
CFBP5499_11485	COG2205	protein histidine kinase activity
CFBP5499_11525	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_11530	COG4605	iron ion homeostasis
CFBP5499_11535	COG4604	ABC transporter, ATP-binding protein
CFBP5499_11540	COG0783	Belongs to the Dps family
CFBP5499_11560	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_11565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_11570	COG0583	DNA-binding transcription factor activity
CFBP5499_11580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_11600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFBP5499_11605	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
CFBP5499_11610	COG0288	reversible hydration of carbon dioxide
CFBP5499_11620	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFBP5499_11640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CFBP5499_11645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5499_11650	COG0778	Nitroreductase
CFBP5499_11655	COG2267	carboxylic ester hydrolase activity
CFBP5499_11660	COG0251	oxidation-reduction process
CFBP5499_11665	COG1335	isochorismatase
CFBP5499_11670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_11680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_11695	COG1175	transmembrane transport
CFBP5499_11700	COG0395	ABC-type sugar transport system, permease component
CFBP5499_11705	COG3842	ATPase activity
CFBP5499_11710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_11720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_11735	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_11740	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_11750	COG0601	transmembrane transport
CFBP5499_11770	COG0392	lysyltransferase activity
CFBP5499_11770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFBP5499_11805	COG2159	amidohydrolase
CFBP5499_11810	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_11835	COG0450	alkyl hydroperoxide reductase
CFBP5499_11855	COG2205	protein histidine kinase activity
CFBP5499_11860	COG0745	RESPONSE REGULATOR receiver
CFBP5499_11870	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_11870	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_11880	COG3192	ethanolamine utilization protein
CFBP5499_11940	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CFBP5499_11950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_11955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5499_11965	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFBP5499_11975	COG1509	lysine 2,3-aminomutase activity
CFBP5499_11990	COG0583	DNA-binding transcription factor activity
CFBP5499_11995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_12000	COG0725	ABC transporter, periplasmic molybdate-binding protein
CFBP5499_12005	COG4149	molybdate abc transporter
CFBP5499_12010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CFBP5499_12020	COG3191	aminopeptidase activity
CFBP5499_12025	COG2022	thiamine diphosphate biosynthetic process
CFBP5499_12040	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFBP5499_12045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_12055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFBP5499_12080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CFBP5499_12080	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5499_12105	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_12125	COG4166	transmembrane transport
CFBP5499_12130	COG0601	transmembrane transport
CFBP5499_12135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_12145	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_12150	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFBP5499_12155	COG3142	Participates in the control of copper homeostasis
CFBP5499_12160	COG2814	Major facilitator Superfamily
CFBP5499_12175	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_12180	COG1737	Transcriptional regulator
CFBP5499_12190	COG3842	ATPase activity
CFBP5499_12200	COG0395	ABC-type sugar transport system, permease component
CFBP5499_12205	COG1175	transmembrane transport
CFBP5499_12230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFBP5499_12235	COG1940	carbohydrate kinase activity
CFBP5499_12245	COG0671	phosphoesterase, PA-phosphatase related
CFBP5499_12250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CFBP5499_12255	COG0156	8-amino-7-oxononanoate synthase activity
CFBP5499_12265	COG0729	surface antigen
CFBP5499_12275	COG0835	chemotaxis
CFBP5499_12285	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFBP5499_12290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CFBP5499_12295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFBP5499_12300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFBP5499_12305	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFBP5499_12310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFBP5499_12325	COG4974	Belongs to the 'phage' integrase family
CFBP5499_12350	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_12360	COG0508	dehydrogenase complex catalyzes the overall conversion of
CFBP5499_12370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFBP5499_12375	COG0045	succinate-CoA ligase (ADP-forming) activity
CFBP5499_12380	COG0039	L-malate dehydrogenase activity
CFBP5499_12385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CFBP5499_12420	COG2264	protein methyltransferase activity
CFBP5499_12435	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP5499_12440	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFBP5499_12445	COG0181	hydroxymethylbilane synthase activity
CFBP5499_12470	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP5499_12490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CFBP5499_12505	COG0339	signal peptide processing
CFBP5499_12510	COG1846	Transcriptional regulator
CFBP5499_12515	COG2814	Major facilitator Superfamily
CFBP5499_12520	COG0137	argininosuccinate synthase activity
CFBP5499_12530	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_12535	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP5499_12540	COG4120	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_12550	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CFBP5499_12565	COG2154	pterin-4-alpha-carbinolamine dehydratase
CFBP5499_12570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFBP5499_12575	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFBP5499_12585	COG4181	ATPase activity
CFBP5499_12595	COG0670	Belongs to the BI1 family
CFBP5499_12610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFBP5499_12615	COG4133	protoheme IX ABC transporter activity
CFBP5499_12625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP5499_12630	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CFBP5499_12645	COG3706	GGDEF domain
CFBP5499_12655	COG2917	probably involved in intracellular septation
CFBP5499_12660	COG0552	protein localization to endoplasmic reticulum
CFBP5499_12665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFBP5499_12670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFBP5499_12685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFBP5499_12690	COG1605	Chorismate mutase
CFBP5499_12690	COG0287	Prephenate dehydrogenase
CFBP5499_12695	COG0228	four-way junction DNA binding
CFBP5499_12700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFBP5499_12705	COG0336	Belongs to the RNA methyltransferase TrmD family
CFBP5499_12715	COG0335	large ribosomal subunit rRNA binding
CFBP5499_12725	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_12730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_12750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFBP5499_12755	COG4783	chaperone-mediated protein folding
CFBP5499_12765	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CFBP5499_12795	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CFBP5499_12805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CFBP5499_12810	COG0142	geranyltranstransferase activity
CFBP5499_12815	COG2885	chlorophyll binding
CFBP5499_12820	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFBP5499_12825	COG2223	nitrite transmembrane transporter activity
CFBP5499_12830	COG1349	DNA-binding transcription factor activity
CFBP5499_12835	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFBP5499_12840	COG2197	response regulator
CFBP5499_12845	COG1132	(ABC) transporter
CFBP5499_12855	COG3459	Glycosyltransferase 36 associated
CFBP5499_12860	COG1473	amidohydrolase
CFBP5499_12870	COG0579	oxidoreductase
CFBP5499_12880	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_12885	COG2084	Dehydrogenase
CFBP5499_12890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_12895	COG0277	FAD linked oxidase domain protein
CFBP5499_12900	COG2186	Transcriptional regulator
CFBP5499_12910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5499_12915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_12920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_12925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP5499_12940	COG0495	leucyl-tRNA aminoacylation
CFBP5499_12975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_12980	COG1946	Acyl-CoA thioesterase
CFBP5499_12985	COG0347	Belongs to the P(II) protein family
CFBP5499_12990	COG0004	ammonium transporteR
CFBP5499_12995	COG1674	ftsk spoiiie
CFBP5499_13000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CFBP5499_13015	COG0745	RESPONSE REGULATOR receiver
CFBP5499_13025	COG1329	Transcriptional regulator
CFBP5499_13030	COG2902	Dehydrogenase
CFBP5499_13035	COG2270	Major facilitator Superfamily
CFBP5499_13050	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_13065	COG0494	nUDIX hydrolase
CFBP5499_13075	COG0793	Belongs to the peptidase S41A family
CFBP5499_13085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFBP5499_13090	COG0799	negative regulation of ribosome biogenesis
CFBP5499_13095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFBP5499_13100	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFBP5499_13105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFBP5499_13110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFBP5499_13125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CFBP5499_13130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CFBP5499_13155	COG0066	3-isopropylmalate dehydratase activity
CFBP5499_13160	COG0473	3-isopropylmalate dehydrogenase activity
CFBP5499_13165	COG1858	cytochrome C peroxidase
CFBP5499_13170	COG1797	cobyrinic acid a,c-diamide synthase activity
CFBP5499_13175	COG1648	precorrin-2 dehydrogenase activity
CFBP5499_13175	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5499_13180	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CFBP5499_13245	COG1492	cobalamin metabolic process
CFBP5499_13260	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_13265	COG3254	rhamnose metabolic process
CFBP5499_13270	COG0246	Mannitol dehydrogenase
CFBP5499_13275	COG1063	alcohol dehydrogenase
CFBP5499_13290	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_13295	COG4214	carbohydrate transport
CFBP5499_13300	COG1129	ABC transporter
CFBP5499_13305	COG2186	Transcriptional regulator
CFBP5499_13310	COG2721	sulfolactate sulfo-lyase activity
CFBP5499_13315	COG0138	bifunctional purine biosynthesis protein purh
CFBP5499_13325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFBP5499_13325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFBP5499_13330	COG0501	Belongs to the peptidase M48B family
CFBP5499_13340	COG1475	DNA binding
CFBP5499_13345	COG1192	Involved in chromosome partitioning
CFBP5499_13350	COG0357	Ribosomal RNA small subunit methyltransferase G
CFBP5499_13355	COG0445	tRNA wobble uridine modification
CFBP5499_13360	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFBP5499_13365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFBP5499_13375	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFBP5499_13385	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CFBP5499_13390	COG0424	maF-like protein
CFBP5499_13395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_13400	COG0237	dephospho-CoA kinase activity
CFBP5499_13410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CFBP5499_13415	COG3030	protein affecting phage T7 exclusion by the F plasmid
CFBP5499_13440	COG0187	DNA topoisomerase II activity
CFBP5499_13450	COG0179	Fumarylacetoacetate (FAA) hydrolase
CFBP5499_13465	COG0135	phosphoribosylanthranilate isomerase activity
CFBP5499_13470	COG0133	tryptophan synthase activity
CFBP5499_13475	COG0159	tryptophan synthase activity
CFBP5499_13480	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFBP5499_13505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CFBP5499_13515	COG2205	protein histidine kinase activity
CFBP5499_13525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CFBP5499_13530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5499_13535	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CFBP5499_13535	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CFBP5499_13540	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFBP5499_13545	COG0642	Histidine kinase
CFBP5499_13550	COG0745	RESPONSE REGULATOR receiver
CFBP5499_13555	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFBP5499_13565	COG1652	LysM domain
CFBP5499_13570	COG1072	(Pantothenic acid kinase))
CFBP5499_13575	COG0140	phosphoribosyl-ATP diphosphatase activity
CFBP5499_13580	COG0107	imidazoleglycerol-phosphate synthase activity
CFBP5499_13585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFBP5499_13590	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFBP5499_13600	COG0131	Imidazoleglycerol-phosphate dehydratase
CFBP5499_13605	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFBP5499_13610	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFBP5499_13620	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CFBP5499_13635	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CFBP5499_13645	COG1643	Atp-dependent helicase
CFBP5499_13690	COG1017	nitric oxide dioxygenase activity
CFBP5499_13690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFBP5499_13695	COG1126	abc transporter atp-binding protein
CFBP5499_13700	COG0765	amino acid transport
CFBP5499_13705	COG4597	amino acid ABC transporter
CFBP5499_13710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_13715	COG0583	DNA-binding transcription factor activity
CFBP5499_13720	COG0514	ATP-dependent DNA helicase (RecQ)
CFBP5499_13745	COG1072	(Pantothenic acid kinase))
CFBP5499_13755	COG1780	Probably involved in ribonucleotide reductase function
CFBP5499_13775	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFBP5499_13800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_13810	COG2813	Specifically methylates the guanine in position
CFBP5499_13815	COG1185	polyribonucleotide nucleotidyltransferase activity
CFBP5499_13820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFBP5499_13825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFBP5499_13830	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFBP5499_13835	COG3064	Membrane
CFBP5499_13835	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFBP5499_13850	COG0779	Required for maturation of 30S ribosomal subunits
CFBP5499_13855	COG2814	Major facilitator Superfamily
CFBP5499_13860	COG2951	lytic endotransglycosylase activity
CFBP5499_13865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFBP5499_13875	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFBP5499_13880	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFBP5499_13895	COG2816	NAD+ diphosphatase activity
CFBP5499_13900	COG0077	Prephenate dehydratase
CFBP5499_13900	COG1605	Chorismate mutase
CFBP5499_13905	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CFBP5499_13910	COG3474	cytochrome
CFBP5499_13920	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CFBP5499_13925	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP5499_13935	COG1278	Cold shock
CFBP5499_13945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_13955	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5499_13955	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFBP5499_13960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CFBP5499_13995	COG2900	Belongs to the SlyX family
CFBP5499_14005	COG0484	heat shock protein binding
CFBP5499_14010	COG0443	Heat shock 70 kDa protein
CFBP5499_14025	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFBP5499_14055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFBP5499_14060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFBP5499_14065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CFBP5499_14075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFBP5499_14080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFBP5499_14085	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFBP5499_14095	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CFBP5499_14100	COG1845	cytochrome c oxidase, subunit III
CFBP5499_14105	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5499_14115	COG0477	Major facilitator Superfamily
CFBP5499_14120	COG0070	glutamate synthase
CFBP5499_14120	COG0067	glutamate synthase
CFBP5499_14120	COG0069	glutamate synthase activity
CFBP5499_14125	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFBP5499_14140	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CFBP5499_14150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFBP5499_14185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_14205	COG0848	biopolymer transport protein
CFBP5499_14215	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5499_14235	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5499_14240	COG3454	Phosphonate metabolism
CFBP5499_14245	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CFBP5499_14250	COG3639	organic phosphonate transmembrane transporter activity
CFBP5499_14255	COG3639	organic phosphonate transmembrane transporter activity
CFBP5499_14265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CFBP5499_14275	COG4778	phosphonate C-P lyase system protein PhnL
CFBP5499_14280	COG4107	phosphonate C-P lyase system protein PhnK
CFBP5499_14285	COG3627	carbon phosphorus lyase activity
CFBP5499_14290	COG3626	phosphonate metabolism
CFBP5499_14295	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CFBP5499_14300	COG3624	Phosphonate C-P lyase system protein PhnG
CFBP5499_14305	COG2188	Transcriptional regulator
CFBP5499_14310	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CFBP5499_14315	COG0837	glucose binding
CFBP5499_14320	COG1803	Methylglyoxal synthase
CFBP5499_14325	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CFBP5499_14330	COG4166	transmembrane transport
CFBP5499_14335	COG4174	ABC transporter (Permease)
CFBP5499_14340	COG4239	(ABC) transporter, permease
CFBP5499_14345	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_14350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_14355	COG0174	glutamine synthetase
CFBP5499_14360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_14365	COG3265	gluconokinase activity
CFBP5499_14370	COG1174	glycine betaine transport
CFBP5499_14375	COG1125	glycine betaine transport
CFBP5499_14380	COG1174	glycine betaine transport
CFBP5499_14385	COG1732	Glycine betaine
CFBP5499_14395	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_14400	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_14415	COG0697	spore germination
CFBP5499_14430	COG0791	NLP P60 protein
CFBP5499_14440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFBP5499_14445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFBP5499_14480	COG4964	Belongs to the GSP D family
CFBP5499_14535	COG3422	double-strand break repair
CFBP5499_14540	COG3757	hydrolase, family 25
CFBP5499_14545	COG0697	spore germination
CFBP5499_14550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_14570	COG0481	GTPase activity
CFBP5499_14575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5499_14590	COG1396	sequence-specific DNA binding
CFBP5499_14605	COG1917	Cupin 2, conserved barrel domain protein
CFBP5499_14605	COG2169	Transcriptional regulator
CFBP5499_14610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP5499_14635	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFBP5499_14640	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CFBP5499_14645	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFBP5499_14655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFBP5499_14660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFBP5499_14660	COG0072	phenylalanine-tRNA ligase activity
CFBP5499_14665	COG0667	Aldo Keto reductase
CFBP5499_14685	COG4977	sequence-specific DNA binding
CFBP5499_14710	COG1570	exodeoxyribonuclease VII activity
CFBP5499_14715	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_14725	COG1846	Transcriptional regulator
CFBP5499_14730	COG0697	spore germination
CFBP5499_14735	COG2309	aminopeptidase activity
CFBP5499_14740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFBP5499_14745	COG1393	Belongs to the ArsC family
CFBP5499_14770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CFBP5499_14770	COG0519	Catalyzes the synthesis of GMP from XMP
CFBP5499_14815	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFBP5499_14825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFBP5499_14835	COG1968	undecaprenyl-diphosphatase activity
CFBP5499_14855	COG0284	orotidine-5'-phosphate decarboxylase activity
CFBP5499_14865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CFBP5499_14870	COG0592	DNA-directed DNA polymerase activity
CFBP5499_14875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFBP5499_14880	COG0792	nuclease activity
CFBP5499_14885	COG0110	maltose O-acetyltransferase activity
CFBP5499_14895	COG1175	transmembrane transport
CFBP5499_14900	COG0395	ABC-type sugar transport system, permease component
CFBP5499_14905	COG3842	ATPase activity
CFBP5499_14915	COG0189	ligase activity
CFBP5499_14920	COG0606	chelatase, subunit chli
CFBP5499_14925	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CFBP5499_14930	COG1280	lysine exporter protein (LysE YggA)
CFBP5499_14935	COG0756	dUTP diphosphatase activity
CFBP5499_14940	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFBP5499_14945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFBP5499_14960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CFBP5499_14965	COG2226	methyltransferase
CFBP5499_14970	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CFBP5499_14975	COG1024	Enoyl-CoA hydratase
CFBP5499_14980	COG0268	Binds directly to 16S ribosomal RNA
CFBP5499_14990	COG2161	toxin-antitoxin pair type II binding
CFBP5499_15000	COG3550	peptidyl-serine autophosphorylation
CFBP5499_15005	COG1396	sequence-specific DNA binding
CFBP5499_15065	COG1132	(ABC) transporter
CFBP5499_15080	COG0583	DNA-binding transcription factor activity
CFBP5499_15085	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_15100	COG3842	ATPase activity
CFBP5499_15110	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_15115	COG1840	ABC-type Fe3 transport system, periplasmic component
CFBP5499_15120	COG0745	RESPONSE REGULATOR receiver
CFBP5499_15135	COG0697	spore germination
CFBP5499_15140	COG0583	DNA-binding transcription factor activity
CFBP5499_15165	COG0745	RESPONSE REGULATOR receiver
CFBP5499_15170	COG2205	protein histidine kinase activity
CFBP5499_15175	COG1764	response to oxidative stress
CFBP5499_15185	COG0596	Alpha beta hydrolase
CFBP5499_15200	COG0783	Belongs to the Dps family
CFBP5499_15205	COG0243	molybdopterin cofactor binding
CFBP5499_15215	COG4566	intracellular signal transduction
CFBP5499_15230	COG2140	Oxalate decarboxylase
CFBP5499_15260	COG1522	sequence-specific DNA binding
CFBP5499_15265	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_15270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_15275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_15280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFBP5499_15285	COG2423	ornithine cyclodeaminase activity
CFBP5499_15290	COG0006	proline dipeptidase activity
CFBP5499_15295	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP5499_15300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_15305	COG0765	amino acid transport
CFBP5499_15310	COG0765	amino acid transport
CFBP5499_15315	COG1126	abc transporter atp-binding protein
CFBP5499_15325	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_15335	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_15340	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_15345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_15350	COG1129	ABC transporter
CFBP5499_15370	COG3284	Transcriptional regulator
CFBP5499_15375	COG1063	alcohol dehydrogenase
CFBP5499_15395	COG0110	maltose O-acetyltransferase activity
CFBP5499_15405	COG0840	transmembrane signaling receptor activity
CFBP5499_15410	COG1049	propionate catabolic process, 2-methylcitrate cycle
CFBP5499_15435	COG0488	(ABC) transporter
CFBP5499_15440	COG5265	(ABC) transporter
CFBP5499_15445	COG3181	Tripartite tricarboxylate transporter family receptor
CFBP5499_15450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFBP5499_15475	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5499_15485	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_15495	COG0405	Gamma-glutamyltransferase
CFBP5499_15505	COG0601	transmembrane transport
CFBP5499_15510	COG0747	negative chemotaxis
CFBP5499_15515	COG2186	Transcriptional regulator
CFBP5499_15525	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_15530	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_15535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_15540	COG0601	transmembrane transport
CFBP5499_15545	COG0747	negative chemotaxis
CFBP5499_15550	COG2186	Transcriptional regulator
CFBP5499_15560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_15575	COG3383	formate dehydrogenase (NAD+) activity
CFBP5499_15600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5499_15605	COG1802	Transcriptional regulator
CFBP5499_15610	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_15615	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_15620	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5499_15630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_15645	COG0402	S-adenosylhomocysteine deaminase activity
CFBP5499_15660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_15670	COG0765	amino acid transport
CFBP5499_15680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_15690	COG1609	Transcriptional regulator
CFBP5499_15695	COG3938	Belongs to the proline racemase family
CFBP5499_15705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_15715	COG0765	amino acid transport
CFBP5499_15730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5499_15735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_15745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5499_15750	COG0784	Response regulator, receiver
CFBP5499_15765	COG0842	Transport permease protein
CFBP5499_15770	COG0842	Transport permease protein
CFBP5499_15770	COG1129	ABC transporter
CFBP5499_15775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_15780	COG1486	melibiose metabolic process
CFBP5499_15785	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_15790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_15795	COG0601	transmembrane transport
CFBP5499_15800	COG0747	negative chemotaxis
CFBP5499_15805	COG1486	melibiose metabolic process
CFBP5499_15830	COG1940	carbohydrate kinase activity
CFBP5499_15835	COG2182	Extracellular solute-binding protein
CFBP5499_15840	COG1175	transmembrane transport
CFBP5499_15845	COG0395	ABC-type sugar transport system, permease component
CFBP5499_15850	COG0165	Argininosuccinate lyase
CFBP5499_15855	COG3842	ATPase activity
CFBP5499_15860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_15865	COG3119	arylsulfatase activity
CFBP5499_15875	COG0583	DNA-binding transcription factor activity
CFBP5499_15880	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_15895	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CFBP5499_15910	COG5002	protein histidine kinase activity
CFBP5499_15915	COG0745	RESPONSE REGULATOR receiver
CFBP5499_15935	COG1392	Phosphate transport regulator
CFBP5499_15940	COG0306	phosphate transporter
CFBP5499_15945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5499_15960	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_15990	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CFBP5499_16000	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFBP5499_16010	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_16015	COG3300	MHYT domain
CFBP5499_16015	COG5001	Diguanylate cyclase
CFBP5499_16025	COG0747	negative chemotaxis
CFBP5499_16030	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5499_16035	COG2186	Transcriptional regulator
CFBP5499_16040	COG0601	transmembrane transport
CFBP5499_16045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_16050	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_16055	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_16060	COG0210	DNA helicase
CFBP5499_16065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFBP5499_16075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CFBP5499_16140	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFBP5499_16145	COG1091	dTDP-4-dehydrorhamnose reductase activity
CFBP5499_16150	COG1088	dTDP-glucose 4,6-dehydratase activity
CFBP5499_16155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CFBP5499_16160	COG1132	(ABC) transporter
CFBP5499_16170	COG0583	DNA-binding transcription factor activity
CFBP5499_16175	COG0667	Aldo Keto reductase
CFBP5499_16180	COG0385	Bile acid
CFBP5499_16200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5499_16245	COG1177	transmembrane transport
CFBP5499_16250	COG3842	ATPase activity
CFBP5499_16260	COG1940	carbohydrate kinase activity
CFBP5499_16260	COG1846	Transcriptional regulator
CFBP5499_16270	COG0300	oxidoreductase activity
CFBP5499_16275	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_16280	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP5499_16290	COG4149	molybdate abc transporter
CFBP5499_16295	COG3842	ATPase activity
CFBP5499_16305	COG1940	carbohydrate kinase activity
CFBP5499_16315	COG3712	iron ion homeostasis
CFBP5499_16320	COG4774	siderophore transport
CFBP5499_16325	COG2814	Major facilitator Superfamily
CFBP5499_16345	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP5499_16360	COG1175	transmembrane transport
CFBP5499_16365	COG0395	ABC-type sugar transport system, permease component
CFBP5499_16370	COG1609	Transcriptional regulator
CFBP5499_16380	COG0673	inositol 2-dehydrogenase activity
CFBP5499_16385	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_16395	COG1609	Transcriptional regulator
CFBP5499_16400	COG0183	Belongs to the thiolase family
CFBP5499_16405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CFBP5499_16415	COG1414	Transcriptional regulator
CFBP5499_16430	COG0583	DNA-binding transcription factor activity
CFBP5499_16440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFBP5499_16445	COG3485	protocatechuate 3,4-dioxygenase
CFBP5499_16450	COG3485	protocatechuate 3,4-dioxygenase
CFBP5499_16460	COG0765	amino acid transport
CFBP5499_16465	COG0765	amino acid transport
CFBP5499_16470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_16475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_16480	COG1126	abc transporter atp-binding protein
CFBP5499_16485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_16490	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CFBP5499_16520	COG0747	negative chemotaxis
CFBP5499_16530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_16545	COG0683	leucine binding
CFBP5499_16560	COG0411	ABC transporter
CFBP5499_16575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_16580	COG3962	Belongs to the TPP enzyme family
CFBP5499_16585	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_16590	COG3718	enzyme involved in inositol metabolism
CFBP5499_16595	COG0673	inositol 2-dehydrogenase activity
CFBP5499_16600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_16610	COG1609	Transcriptional regulator
CFBP5499_16615	COG1846	Transcriptional regulator
CFBP5499_16625	COG0523	cobalamin synthesis protein
CFBP5499_16660	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CFBP5499_16680	COG0800	Aldolase
CFBP5499_16695	COG0747	negative chemotaxis
CFBP5499_16700	COG0601	transmembrane transport
CFBP5499_16705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_16710	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_16715	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_16720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CFBP5499_16735	COG0346	lactoylglutathione lyase activity
CFBP5499_16745	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_16755	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_16760	COG1129	ABC transporter
CFBP5499_16765	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_16770	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_16775	COG2186	Transcriptional regulator
CFBP5499_16790	COG0587	DNA-directed DNA polymerase activity
CFBP5499_16795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5499_16820	COG0673	inositol 2-dehydrogenase activity
CFBP5499_16830	COG3842	ATPase activity
CFBP5499_16835	COG0395	ABC-type sugar transport system, permease component
CFBP5499_16840	COG1175	transmembrane transport
CFBP5499_16845	COG1653	transport
CFBP5499_16855	COG0673	inositol 2-dehydrogenase activity
CFBP5499_16870	COG5001	Diguanylate cyclase
CFBP5499_16875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_16885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CFBP5499_16890	COG2894	cell division
CFBP5499_16895	COG0850	regulation of cytokinetic process
CFBP5499_16905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_16910	COG2186	Transcriptional regulator
CFBP5499_16915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_16925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_16930	COG1063	alcohol dehydrogenase
CFBP5499_16935	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5499_16950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_16955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_16960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_16970	COG0640	Transcriptional regulator
CFBP5499_16975	COG0625	glutathione transferase activity
CFBP5499_16985	COG1921	L-seryl-tRNASec selenium transferase activity
CFBP5499_17000	COG3964	amidohydrolase
CFBP5499_17010	COG0601	transmembrane transport
CFBP5499_17015	COG0747	negative chemotaxis
CFBP5499_17025	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_17065	COG4989	oxidoreductase activity
CFBP5499_17080	COG3842	ATPase activity
CFBP5499_17085	COG1653	transport
CFBP5499_17090	COG1175	transmembrane transport
CFBP5499_17095	COG0395	ABC-type sugar transport system, permease component
CFBP5499_17100	COG1501	Belongs to the glycosyl hydrolase 31 family
CFBP5499_17115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_17120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_17125	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFBP5499_17130	COG0352	thiamine-phosphate diphosphorylase activity
CFBP5499_17135	COG0351	phosphomethylpyrimidine kinase
CFBP5499_17145	COG1522	sequence-specific DNA binding
CFBP5499_17150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFBP5499_17155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_17170	COG2204	response regulator
CFBP5499_17175	COG4191	Histidine kinase
CFBP5499_17180	COG1301	dicarboxylic acid transport
CFBP5499_17190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_17195	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_17225	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_17235	COG2942	2-epimerase
CFBP5499_17270	COG2197	response regulator
CFBP5499_17300	COG3307	-O-antigen
CFBP5499_17305	COG1596	polysaccharide export
CFBP5499_17310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CFBP5499_17330	COG2972	Histidine kinase
CFBP5499_17330	COG0840	transmembrane signaling receptor activity
CFBP5499_17335	COG1388	LysM domain
CFBP5499_17335	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_17345	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_17355	COG2094	Belongs to the DNA glycosylase MPG family
CFBP5499_17370	COG1609	Transcriptional regulator
CFBP5499_17375	COG1653	transport
CFBP5499_17390	COG3842	ATPase activity
CFBP5499_17400	COG0673	inositol 2-dehydrogenase activity
CFBP5499_17405	COG0602	queuosine metabolic process
CFBP5499_17410	COG0720	synthase
CFBP5499_17415	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFBP5499_17420	COG0673	inositol 2-dehydrogenase activity
CFBP5499_17435	COG0395	ABC-type sugar transport system, permease component
CFBP5499_17460	COG0583	DNA-binding transcription factor activity
CFBP5499_17465	COG0280	phosphate acetyltransferase
CFBP5499_17465	COG0281	malic enzyme
CFBP5499_17480	COG0765	amino acid transport
CFBP5499_17485	COG1126	abc transporter atp-binding protein
CFBP5499_17490	COG2079	MmgE PrpD family protein
CFBP5499_17505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_17525	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CFBP5499_17530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_17535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CFBP5499_17540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CFBP5499_17545	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_17550	COG1129	ABC transporter
CFBP5499_17565	COG1473	amidohydrolase
CFBP5499_17570	COG0747	negative chemotaxis
CFBP5499_17590	COG0601	transmembrane transport
CFBP5499_17595	COG0583	DNA-binding transcription factor activity
CFBP5499_17600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_17605	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_17625	COG1595	DNA-templated transcription, initiation
CFBP5499_17630	COG1120	ATPase activity
CFBP5499_17635	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_17650	COG2226	methyltransferase
CFBP5499_17660	COG1120	ATPase activity
CFBP5499_17665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_17685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5499_17695	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_17700	COG0473	3-isopropylmalate dehydrogenase activity
CFBP5499_17705	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_17710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_17745	COG0601	transmembrane transport
CFBP5499_17750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_17755	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_17760	COG1522	sequence-specific DNA binding
CFBP5499_17765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_17780	COG1126	abc transporter atp-binding protein
CFBP5499_17790	COG1473	amidohydrolase
CFBP5499_17795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_17800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_17805	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_17815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFBP5499_17820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_17845	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_17880	COG0667	Aldo Keto reductase
CFBP5499_17890	COG0583	DNA-binding transcription factor activity
CFBP5499_17910	COG0747	negative chemotaxis
CFBP5499_17915	COG1473	amidohydrolase
CFBP5499_17920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_17960	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_17965	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_17975	COG0601	transmembrane transport
CFBP5499_17985	COG2186	Transcriptional regulator
CFBP5499_18000	COG0300	oxidoreductase activity
CFBP5499_18010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5499_18010	COG3453	Protein conserved in bacteria
CFBP5499_18015	COG0640	Transcriptional regulator
CFBP5499_18025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFBP5499_18040	COG0022	dehydrogenase e1 component
CFBP5499_18050	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_18055	COG0183	Belongs to the thiolase family
CFBP5499_18065	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_18070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP5499_18085	COG1024	Enoyl-CoA hydratase
CFBP5499_18090	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFBP5499_18095	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CFBP5499_18100	COG4952	isomerase
CFBP5499_18105	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_18105	COG3347	Dehydrogenase
CFBP5499_18110	COG1349	DNA-binding transcription factor activity
CFBP5499_18115	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_18120	COG1129	ABC transporter
CFBP5499_18125	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_18135	COG3254	rhamnose metabolic process
CFBP5499_18150	COG2264	protein methyltransferase activity
CFBP5499_18155	COG5001	Diguanylate cyclase
CFBP5499_18175	COG4335	DNA alkylation repair
CFBP5499_18180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CFBP5499_18185	COG4208	sulfate ABC transporter
CFBP5499_18195	COG4150	thiosulfate binding
CFBP5499_18215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CFBP5499_18225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CFBP5499_18235	COG1040	competence protein
CFBP5499_18240	COG2226	methyltransferase
CFBP5499_18255	COG0494	nUDIX hydrolase
CFBP5499_18265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFBP5499_18270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CFBP5499_18275	COG0653	protein targeting
CFBP5499_18280	COG0697	spore germination
CFBP5499_18320	COG1312	Catalyzes the dehydration of D-mannonate
CFBP5499_18325	COG0246	Mannitol dehydrogenase
CFBP5499_18330	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_18345	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_18350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_18355	COG1129	ABC transporter
CFBP5499_18385	COG2376	Dihydroxyacetone kinase
CFBP5499_18390	COG3273	potassium ion transport
CFBP5499_18390	COG0471	metal ion transport
CFBP5499_18420	COG2244	polysaccharide biosynthetic process
CFBP5499_18435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5499_18445	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5499_18445	COG0489	protein tyrosine kinase activity
CFBP5499_18465	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_18470	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_18490	COG2273	Hydrolase Family 16
CFBP5499_18490	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CFBP5499_18535	COG1396	sequence-specific DNA binding
CFBP5499_18545	COG1129	ABC transporter
CFBP5499_18550	COG4214	carbohydrate transport
CFBP5499_18555	COG4213	ABC transporter substrate-binding protein
CFBP5499_18590	COG0625	glutathione transferase activity
CFBP5499_18595	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CFBP5499_18600	COG1396	sequence-specific DNA binding
CFBP5499_18600	COG3800	Transcriptional regulator
CFBP5499_18610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP5499_18620	COG0300	oxidoreductase activity
CFBP5499_18630	COG2096	Adenosyltransferase
CFBP5499_18640	COG2086	electron transfer activity
CFBP5499_18650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CFBP5499_18660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CFBP5499_18665	COG0165	Argininosuccinate lyase
CFBP5499_18705	COG2884	Cell division ATP-binding protein ftsE
CFBP5499_18725	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CFBP5499_18735	COG0287	Prephenate dehydrogenase
CFBP5499_18740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFBP5499_18745	COG2226	methyltransferase
CFBP5499_18750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CFBP5499_18770	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CFBP5499_18775	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFBP5499_18810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFBP5499_18815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFBP5499_18830	COG4974	Belongs to the 'phage' integrase family
CFBP5499_18835	COG0825	malonyl-CoA metabolic process
CFBP5499_18840	COG3034	peptidoglycan biosynthetic process
CFBP5499_18845	COG0425	Belongs to the sulfur carrier protein TusA family
CFBP5499_18845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFBP5499_18850	COG0523	cobalamin synthesis protein
CFBP5499_18855	COG1686	Belongs to the peptidase S11 family
CFBP5499_18860	COG1473	amidohydrolase
CFBP5499_18865	COG1959	2 iron, 2 sulfur cluster binding
CFBP5499_18870	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFBP5499_18880	COG0534	Mate efflux family protein
CFBP5499_18915	COG2226	methyltransferase
CFBP5499_18970	COG4774	siderophore transport
CFBP5499_18970	COG1629	transport
CFBP5499_18975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CFBP5499_18980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_18985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFBP5499_18990	COG1120	ATPase activity
CFBP5499_19005	COG4953	penicillin-binding protein 1C
CFBP5499_19010	COG2373	Large extracellular alpha-helical protein
CFBP5499_19015	COG2835	tetraacyldisaccharide 4'-kinase activity
CFBP5499_19025	COG3118	belongs to the thioredoxin family
CFBP5499_19040	COG0625	glutathione transferase activity
CFBP5499_19195	COG4383	Mu-like prophage protein gp29
CFBP5499_19215	COG4397	Mu-like prophage major head subunit gpT
CFBP5499_19305	COG0393	Putative heavy-metal-binding
CFBP5499_19315	COG0482	sulfurtransferase activity
CFBP5499_19330	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5499_19345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFBP5499_19350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5499_19355	COG0037	tRNA processing
CFBP5499_19365	COG2885	chlorophyll binding
CFBP5499_19370	COG0823	Involved in the tonB-independent uptake of proteins
CFBP5499_19390	COG0824	Thioesterase
CFBP5499_19400	COG0494	nUDIX hydrolase
CFBP5499_19415	COG2255	four-way junction helicase activity
CFBP5499_19420	COG0632	four-way junction helicase activity
CFBP5499_19425	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CFBP5499_19430	COG0840	transmembrane signaling receptor activity
CFBP5499_19435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_19440	COG0217	transcriptional regulatory protein
CFBP5499_19455	COG1692	metallophosphoesterase
CFBP5499_19465	COG1253	flavin adenine dinucleotide binding
CFBP5499_19505	COG0126	phosphoglycerate kinase activity
CFBP5499_19510	COG3588	fructose-bisphosphate aldolase
CFBP5499_19530	COG0254	rRNA binding
CFBP5499_19535	COG1132	(ABC) transporter
CFBP5499_19555	COG0483	inositol monophosphate 1-phosphatase activity
CFBP5499_19585	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP5499_19590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFBP5499_19595	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CFBP5499_19600	COG0457	Tetratricopeptide repeat
CFBP5499_19605	COG3750	Belongs to the UPF0335 family
CFBP5499_19625	COG0469	pyruvate kinase activity
CFBP5499_19630	COG3108	Peptidase M15
CFBP5499_19635	COG2204	response regulator
CFBP5499_19640	COG1164	Oligoendopeptidase f
CFBP5499_19645	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_19650	COG5310	Homospermidine synthase
CFBP5499_19660	COG0737	Belongs to the 5'-nucleotidase family
CFBP5499_19665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CFBP5499_19670	COG0330	HflC and HflK could
CFBP5499_19700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP5499_19705	COG2951	lytic endotransglycosylase activity
CFBP5499_19720	COG2205	protein histidine kinase activity
CFBP5499_19730	COG0069	glutamate synthase activity
CFBP5499_19730	COG0070	glutamate synthase
CFBP5499_19730	COG0067	glutamate synthase
CFBP5499_19745	COG2205	protein histidine kinase activity
CFBP5499_19750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CFBP5499_19755	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CFBP5499_19760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CFBP5499_19770	COG0252	asparaginase activity
CFBP5499_19780	COG1027	Aspartate ammonia-lyase
CFBP5499_19785	COG2186	Transcriptional regulator
CFBP5499_19805	COG1309	transcriptional regulator
CFBP5499_19825	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_19830	COG4175	Glycine betaine
CFBP5499_19830	COG0517	IMP dehydrogenase activity
CFBP5499_19835	COG2986	histidine ammonia-lyase
CFBP5499_19840	COG2814	Major facilitator Superfamily
CFBP5499_19855	COG1522	sequence-specific DNA binding
CFBP5499_19860	COG0583	DNA-binding transcription factor activity
CFBP5499_19865	COG0667	Aldo Keto reductase
CFBP5499_19875	COG1335	isochorismatase
CFBP5499_19890	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_19895	COG3254	rhamnose metabolic process
CFBP5499_19915	COG2721	sulfolactate sulfo-lyase activity
CFBP5499_19920	COG1129	ABC transporter
CFBP5499_19930	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_19935	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_19945	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFBP5499_19960	COG0583	DNA-binding transcription factor activity
CFBP5499_19970	COG0583	DNA-binding transcription factor activity
CFBP5499_19990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_20005	COG0601	transmembrane transport
CFBP5499_20010	COG0747	negative chemotaxis
CFBP5499_20020	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CFBP5499_20025	COG1454	alcohol dehydrogenase
CFBP5499_20030	COG2186	Transcriptional regulator
CFBP5499_20045	COG1607	acyl-coa hydrolase
CFBP5499_20065	COG2308	Evidence 4 Homologs of previously reported genes of
CFBP5499_20065	COG2307	Protein conserved in bacteria
CFBP5499_20080	COG0488	(ABC) transporter
CFBP5499_20085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_20090	COG1304	FMN binding
CFBP5499_20095	COG1846	Transcriptional regulator
CFBP5499_20100	COG0840	transmembrane signaling receptor activity
CFBP5499_20105	COG1070	Carbohydrate kinase
CFBP5499_20110	COG1830	Aldolase
CFBP5499_20115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFBP5499_20120	COG0667	Aldo Keto reductase
CFBP5499_20135	COG1129	ABC transporter
CFBP5499_20170	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5499_20185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFBP5499_20200	COG0395	ABC-type sugar transport system, permease component
CFBP5499_20215	COG3842	ATPase activity
CFBP5499_20230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CFBP5499_20230	COG1648	precorrin-2 dehydrogenase activity
CFBP5499_20235	COG0243	molybdopterin cofactor binding
CFBP5499_20245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFBP5499_20250	COG1116	anion transmembrane transporter activity
CFBP5499_20255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_20260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_20270	COG3707	response regulator
CFBP5499_20275	COG1802	Transcriptional regulator
CFBP5499_20280	COG1914	H( )-stimulated, divalent metal cation uptake system
CFBP5499_20285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5499_20290	COG4336	lyase activity
CFBP5499_20295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5499_20300	COG4770	biotin carboxylase activity
CFBP5499_20305	COG0366	Alpha amylase catalytic
CFBP5499_20315	COG4771	TonB-dependent receptor
CFBP5499_20320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFBP5499_20340	COG1414	Transcriptional regulator
CFBP5499_20345	COG1475	DNA binding
CFBP5499_20350	COG1192	Involved in chromosome partitioning
CFBP5499_20380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFBP5499_20395	COG2986	histidine ammonia-lyase
CFBP5499_20400	COG1228	amidohydrolase
CFBP5499_20475	COG2079	MmgE PrpD family protein
CFBP5499_20485	COG1126	abc transporter atp-binding protein
CFBP5499_20495	COG0165	Argininosuccinate lyase
CFBP5499_20505	COG0583	DNA-binding transcription factor activity
CFBP5499_20515	COG1609	Transcriptional regulator
CFBP5499_20535	COG0747	negative chemotaxis
CFBP5499_20545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_20550	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_20555	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_20590	COG0477	Major facilitator Superfamily
CFBP5499_20610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_20625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFBP5499_20630	COG3048	D-serine ammonia-lyase activity
CFBP5499_20640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFBP5499_20650	COG0583	DNA-binding transcription factor activity
CFBP5499_20655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_20660	COG4597	amino acid ABC transporter
CFBP5499_20665	COG0765	amino acid transport
CFBP5499_20690	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_20735	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_20740	COG3836	Belongs to the HpcH HpaI aldolase family
CFBP5499_20760	COG0673	inositol 2-dehydrogenase activity
CFBP5499_20765	COG0673	inositol 2-dehydrogenase activity
CFBP5499_20780	COG0395	ABC-type sugar transport system, permease component
CFBP5499_20795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_20800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5499_20820	COG0583	DNA-binding transcription factor activity
CFBP5499_20825	COG0346	lactoylglutathione lyase activity
CFBP5499_20840	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CFBP5499_20850	COG2814	Major facilitator Superfamily
CFBP5499_20860	COG0583	DNA-binding transcription factor activity
CFBP5499_20865	COG0477	Major facilitator Superfamily
CFBP5499_20870	COG2205	protein histidine kinase activity
CFBP5499_20875	COG0745	RESPONSE REGULATOR receiver
CFBP5499_20880	COG0671	phosphoesterase, PA-phosphatase related
CFBP5499_20930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFBP5499_20940	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFBP5499_20945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CFBP5499_20950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFBP5499_20990	COG0697	spore germination
CFBP5499_20995	COG0673	inositol 2-dehydrogenase activity
CFBP5499_21015	COG0477	Major facilitator Superfamily
CFBP5499_21020	COG0642	Histidine kinase
CFBP5499_21025	COG0745	RESPONSE REGULATOR receiver
CFBP5499_21030	COG2194	sulfuric ester hydrolase activity
CFBP5499_21040	COG0583	DNA-binding transcription factor activity
CFBP5499_21045	COG4774	siderophore transport
CFBP5499_21060	COG1120	ATPase activity
CFBP5499_21070	COG3474	cytochrome
CFBP5499_21075	COG2137	regulation of response to DNA damage stimulus
CFBP5499_21080	COG3386	PFAM SMP-30 Gluconolaconase
CFBP5499_21090	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_21095	COG1129	ABC transporter
CFBP5499_21100	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_21110	COG4585	Histidine kinase
CFBP5499_21115	COG2197	response regulator
CFBP5499_21125	COG2133	pyrroloquinoline quinone binding
CFBP5499_21135	COG0500	methyltransferase
CFBP5499_21140	COG0564	pseudouridine synthase activity
CFBP5499_21155	COG4175	Glycine betaine
CFBP5499_21155	COG0517	IMP dehydrogenase activity
CFBP5499_21160	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_21170	COG4191	Histidine kinase
CFBP5499_21170	COG0784	Response regulator, receiver
CFBP5499_21175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CFBP5499_21180	COG0489	protein tyrosine kinase activity
CFBP5499_21180	COG3206	protein involved in exopolysaccharide biosynthesis
CFBP5499_21185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CFBP5499_21190	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_21195	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_21200	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_21205	COG0438	transferase activity, transferring glycosyl groups
CFBP5499_21210	COG2273	Hydrolase Family 16
CFBP5499_21215	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CFBP5499_21220	COG2244	polysaccharide biosynthetic process
CFBP5499_21225	COG0463	Glycosyl transferase, family 2
CFBP5499_21230	COG2327	Polysaccharide pyruvyl transferase
CFBP5499_21235	COG3385	transposase activity
CFBP5499_21240	COG1215	transferase activity, transferring glycosyl groups
CFBP5499_21260	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_21270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_21285	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_21285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_21315	COG0033	Phosphoglucomutase
CFBP5499_21320	COG0297	glycogen (starch) synthase activity
CFBP5499_21325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFBP5499_21330	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP5499_21335	COG0058	SHG alpha-glucan phosphorylase activity
CFBP5499_21350	COG1794	racemase activity, acting on amino acids and derivatives
CFBP5499_21355	COG1522	sequence-specific DNA binding
CFBP5499_21365	COG2084	Dehydrogenase
CFBP5499_21370	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_21375	COG1063	alcohol dehydrogenase
CFBP5499_21385	COG4988	ABC transporter
CFBP5499_21390	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CFBP5499_21400	COG1294	oxidase, subunit
CFBP5499_21430	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CFBP5499_21435	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFBP5499_21465	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CFBP5499_21470	COG0539	negative regulation of cytoplasmic translation
CFBP5499_21500	COG4221	oxidoreductase activity
CFBP5499_21510	COG0006	proline dipeptidase activity
CFBP5499_21515	COG0747	negative chemotaxis
CFBP5499_21520	COG0601	transmembrane transport
CFBP5499_21525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_21530	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_21535	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_21690	COG2369	cell adhesion
CFBP5499_21755	COG4396	Host-nuclease inhibitor protein Gam
CFBP5499_21795	COG1475	DNA binding
CFBP5499_21820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_21840	COG0410	ABC transporter
CFBP5499_21845	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_21865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CFBP5499_21870	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_21890	COG4993	Dehydrogenase
CFBP5499_21895	COG3685	Protein conserved in bacteria
CFBP5499_21920	COG0693	protein deglycase activity
CFBP5499_21945	COG0189	ligase activity
CFBP5499_21950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_21955	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP5499_21965	COG0583	DNA-binding transcription factor activity
CFBP5499_21970	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_21975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_21980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_21985	COG1116	anion transmembrane transporter activity
CFBP5499_22000	COG1522	sequence-specific DNA binding
CFBP5499_22015	COG0784	Response regulator, receiver
CFBP5499_22025	COG3920	Histidine kinase
CFBP5499_22035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CFBP5499_22050	COG0019	diaminopimelate decarboxylase activity
CFBP5499_22060	COG3385	transposase activity
CFBP5499_22075	COG0527	aspartate kinase activity
CFBP5499_22085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFBP5499_22090	COG2890	protein-(glutamine-N5) methyltransferase activity
CFBP5499_22100	COG0542	response to heat
CFBP5499_22105	COG1196	nuclear chromosome segregation
CFBP5499_22105	COG0741	lytic transglycosylase activity
CFBP5499_22105	COG0739	heme binding
CFBP5499_22160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_22160	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_22165	COG4311	Sarcosine oxidase, delta subunit
CFBP5499_22170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_22175	COG4977	sequence-specific DNA binding
CFBP5499_22185	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFBP5499_22190	COG2218	PFAM glutamate synthase alpha subunit domain protein
CFBP5499_22195	COG0069	glutamate synthase activity
CFBP5499_22200	COG0174	glutamine synthetase
CFBP5499_22225	COG1126	abc transporter atp-binding protein
CFBP5499_22240	COG2267	carboxylic ester hydrolase activity
CFBP5499_22250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_22255	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_22270	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_22275	COG1177	transmembrane transport
CFBP5499_22280	COG3842	ATPase activity
CFBP5499_22295	COG0778	Nitroreductase
CFBP5499_22335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_22340	COG0747	negative chemotaxis
CFBP5499_22345	COG0747	negative chemotaxis
CFBP5499_22355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_22365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_22375	COG1129	ABC transporter
CFBP5499_22380	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_22385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_22390	COG1454	alcohol dehydrogenase
CFBP5499_22400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP5499_22405	COG0411	ABC transporter
CFBP5499_22435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_22445	COG0765	amino acid transport
CFBP5499_22465	COG0583	DNA-binding transcription factor activity
CFBP5499_22470	COG0028	Belongs to the TPP enzyme family
CFBP5499_22495	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFBP5499_22500	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_22510	COG1566	PFAM secretion protein HlyD family protein
CFBP5499_22520	COG0625	glutathione transferase activity
CFBP5499_22525	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_22530	COG0596	Alpha beta hydrolase
CFBP5499_22535	COG0395	ABC-type sugar transport system, permease component
CFBP5499_22550	COG2186	Transcriptional regulator
CFBP5499_22565	COG1175	transmembrane transport
CFBP5499_22570	COG0395	ABC-type sugar transport system, permease component
CFBP5499_22580	COG3842	ATPase activity
CFBP5499_22600	COG2171	N-acyltransferase activity
CFBP5499_22610	COG0431	NADPH-dependent FMN reductase
CFBP5499_22620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_22630	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_22635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_22645	COG0747	negative chemotaxis
CFBP5499_22660	COG0277	FAD linked oxidase domain protein
CFBP5499_22700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5499_22720	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CFBP5499_22725	COG0431	NADPH-dependent FMN reductase
CFBP5499_22730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFBP5499_22740	COG0559	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_22755	COG0410	ABC transporter
CFBP5499_22775	COG4211	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_22790	COG0673	inositol 2-dehydrogenase activity
CFBP5499_22810	COG2072	flavoprotein involved in K transport
CFBP5499_22830	COG3842	ATPase activity
CFBP5499_22835	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_22855	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_22880	COG0667	Aldo Keto reductase
CFBP5499_22895	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_22900	COG1129	ABC transporter
CFBP5499_22905	COG4213	ABC transporter substrate-binding protein
CFBP5499_22925	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_22930	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_22940	COG0601	transmembrane transport
CFBP5499_22945	COG0747	negative chemotaxis
CFBP5499_22965	COG0765	amino acid transport
CFBP5499_22970	COG4597	amino acid ABC transporter
CFBP5499_22975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_22980	COG1473	amidohydrolase
CFBP5499_22985	COG2271	Major facilitator Superfamily
CFBP5499_22995	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CFBP5499_23010	COG3842	ATPase activity
CFBP5499_23015	COG0395	ABC-type sugar transport system, permease component
CFBP5499_23030	COG3976	FMN-binding domain protein
CFBP5499_23030	COG1053	succinate dehydrogenase
CFBP5499_23035	COG1609	Transcriptional regulator
CFBP5499_23045	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_23050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_23055	COG0601	transmembrane transport
CFBP5499_23065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_23080	COG2828	Protein conserved in bacteria
CFBP5499_23085	COG0583	DNA-binding transcription factor activity
CFBP5499_23090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CFBP5499_23115	COG0583	DNA-binding transcription factor activity
CFBP5499_23125	COG0511	ligase activity, forming carbon-carbon bonds
CFBP5499_23130	COG0439	Biotin carboxylase
CFBP5499_23145	COG1984	allophanate hydrolase subunit 2
CFBP5499_23150	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CFBP5499_23165	COG4221	oxidoreductase activity
CFBP5499_23170	COG0765	amino acid transport
CFBP5499_23175	COG0765	amino acid transport
CFBP5499_23180	COG1126	abc transporter atp-binding protein
CFBP5499_23185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_23190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CFBP5499_23205	COG0583	DNA-binding transcription factor activity
CFBP5499_23210	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CFBP5499_23215	COG0583	DNA-binding transcription factor activity
CFBP5499_23220	COG2814	Major facilitator Superfamily
CFBP5499_23240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CFBP5499_23245	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFBP5499_23265	COG0047	phosphoribosylformylglycinamidine synthase activity
CFBP5499_23270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_23280	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CFBP5499_23280	COG0446	pyridine nucleotide-disulphide oxidoreductase
CFBP5499_23290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFBP5499_23305	COG1309	transcriptional regulator
CFBP5499_23320	COG1136	(ABC) transporter
CFBP5499_23330	COG1063	alcohol dehydrogenase
CFBP5499_23340	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_23350	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_23370	COG0477	Major facilitator Superfamily
CFBP5499_23380	COG3300	MHYT domain
CFBP5499_23380	COG5001	Diguanylate cyclase
CFBP5499_23390	COG1253	flavin adenine dinucleotide binding
CFBP5499_23405	COG3842	ATPase activity
CFBP5499_23410	COG0395	ABC-type sugar transport system, permease component
CFBP5499_23415	COG1175	transmembrane transport
CFBP5499_23420	COG1653	transport
CFBP5499_23430	COG0673	inositol 2-dehydrogenase activity
CFBP5499_23435	COG1609	Transcriptional regulator
CFBP5499_23450	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_23455	COG1129	ABC transporter
CFBP5499_23460	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_23465	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_23470	COG1609	Transcriptional regulator
CFBP5499_23480	COG0673	inositol 2-dehydrogenase activity
CFBP5499_23510	COG1960	acyl-CoA dehydrogenase activity
CFBP5499_23515	COG0583	DNA-binding transcription factor activity
CFBP5499_23520	COG1609	Transcriptional regulator
CFBP5499_23530	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_23540	COG3842	ATPase activity
CFBP5499_23550	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_23565	COG1473	amidohydrolase
CFBP5499_23580	COG0747	negative chemotaxis
CFBP5499_23585	COG0601	transmembrane transport
CFBP5499_23590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_23595	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_23600	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_23605	COG0583	DNA-binding transcription factor activity
CFBP5499_23610	COG0747	negative chemotaxis
CFBP5499_23620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_23625	COG0154	amidase activity
CFBP5499_23630	COG0693	protein deglycase activity
CFBP5499_23640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_23645	COG0601	transmembrane transport
CFBP5499_23655	COG1473	amidohydrolase
CFBP5499_23660	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_23665	COG2390	Transcriptional regulator
CFBP5499_23675	COG1175	transmembrane transport
CFBP5499_23680	COG0395	ABC-type sugar transport system, permease component
CFBP5499_23695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_23700	COG1069	ribulokinase activity
CFBP5499_23725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFBP5499_23745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFBP5499_23750	COG1414	Transcriptional regulator
CFBP5499_23755	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_23765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5499_23770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CFBP5499_23775	COG1121	(ABC) transporter
CFBP5499_23780	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP5499_23795	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CFBP5499_23805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFBP5499_23810	COG3273	potassium ion transport
CFBP5499_23810	COG0471	metal ion transport
CFBP5499_23815	COG1253	flavin adenine dinucleotide binding
CFBP5499_23820	COG1309	transcriptional regulator
CFBP5499_23835	COG1609	Transcriptional regulator
CFBP5499_23840	COG1070	Carbohydrate kinase
CFBP5499_23850	COG2115	Belongs to the xylose isomerase family
CFBP5499_23870	COG3385	transposase activity
CFBP5499_23875	COG0778	Nitroreductase
CFBP5499_23880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFBP5499_23885	COG2011	ABC-type metal ion transport system permease component
CFBP5499_23895	COG3300	MHYT domain
CFBP5499_23895	COG5001	Diguanylate cyclase
CFBP5499_23910	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CFBP5499_23915	COG5001	Diguanylate cyclase
CFBP5499_23925	COG3257	ureidoglycine aminohydrolase activity
CFBP5499_23935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_23940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFBP5499_23950	COG1129	ABC transporter
CFBP5499_23955	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_23960	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_23965	COG0583	DNA-binding transcription factor activity
CFBP5499_23980	COG3385	transposase activity
CFBP5499_24020	COG0784	Response regulator, receiver
CFBP5499_24020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFBP5499_24055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFBP5499_24075	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFBP5499_24080	COG1473	amidohydrolase
CFBP5499_24095	COG0456	acetyltransferase
CFBP5499_24135	COG1126	abc transporter atp-binding protein
CFBP5499_24140	COG0765	amino acid transport
CFBP5499_24145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CFBP5499_24175	COG3210	domain, Protein
CFBP5499_24175	COG3210	domain, Protein
CFBP5499_24180	COG2831	hemolysin activation secretion protein
CFBP5499_24215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CFBP5499_24235	COG3047	cAMP biosynthetic process
CFBP5499_24245	COG3842	ATPase activity
CFBP5499_24250	COG0395	ABC-type sugar transport system, permease component
CFBP5499_24255	COG1175	transmembrane transport
CFBP5499_24260	COG1653	transport
CFBP5499_24265	COG0523	cobalamin synthesis protein
CFBP5499_24280	COG0523	cobalamin synthesis protein
CFBP5499_24285	COG1121	(ABC) transporter
CFBP5499_24295	COG0803	Belongs to the bacterial solute-binding protein 9 family
CFBP5499_24300	COG0328	RNA-DNA hybrid ribonuclease activity
CFBP5499_24310	COG0626	cystathionine gamma-synthase activity
CFBP5499_24325	COG0395	ABC-type sugar transport system, permease component
CFBP5499_24335	COG1609	Transcriptional regulator
CFBP5499_24350	COG2084	Dehydrogenase
CFBP5499_24355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_24365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_24370	COG0583	DNA-binding transcription factor activity
CFBP5499_24375	COG2223	nitrite transmembrane transporter activity
CFBP5499_24410	COG0667	Aldo Keto reductase
CFBP5499_24425	COG2186	Transcriptional regulator
CFBP5499_24430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_24435	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFBP5499_24440	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_24445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_24450	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_24455	COG3618	amidohydrolase
CFBP5499_24460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_24480	COG1175	transmembrane transport
CFBP5499_24485	COG0395	ABC-type sugar transport system, permease component
CFBP5499_24505	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CFBP5499_24525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CFBP5499_24535	COG1278	Cold shock
CFBP5499_24545	COG0673	inositol 2-dehydrogenase activity
CFBP5499_24560	COG0673	inositol 2-dehydrogenase activity
CFBP5499_24565	COG1309	transcriptional regulator
CFBP5499_24570	COG1653	transport
CFBP5499_24575	COG1175	transmembrane transport
CFBP5499_24580	COG0395	ABC-type sugar transport system, permease component
CFBP5499_24585	COG3842	ATPase activity
CFBP5499_24600	COG1082	Xylose isomerase domain protein TIM barrel
CFBP5499_24605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_24645	COG1175	transmembrane transport
CFBP5499_24650	COG0395	ABC-type sugar transport system, permease component
CFBP5499_24680	COG3842	ATPase activity
CFBP5499_24690	COG3385	transposase activity
CFBP5499_24695	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_24700	COG0395	ABC-type sugar transport system, permease component
CFBP5499_24710	COG1595	DNA-templated transcription, initiation
CFBP5499_24750	COG2233	PERMEase
CFBP5499_24765	COG1309	transcriptional regulator
CFBP5499_24770	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_24800	COG1735	metal-dependent hydrolase with the TIM-barrel fold
CFBP5499_24805	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_24820	COG1609	Transcriptional regulator
CFBP5499_24840	COG0601	transmembrane transport
CFBP5499_24845	COG0747	negative chemotaxis
CFBP5499_24855	COG0583	DNA-binding transcription factor activity
CFBP5499_24860	COG3706	GGDEF domain
CFBP5499_24865	COG4178	(ABC) transporter
CFBP5499_24870	COG1446	asparaginase
CFBP5499_24885	COG0747	negative chemotaxis
CFBP5499_24910	COG0601	transmembrane transport
CFBP5499_24915	COG2197	response regulator
CFBP5499_24940	COG1850	ribulose-bisphosphate carboxylase activity
CFBP5499_24950	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_24960	COG2207	Transcriptional regulator
CFBP5499_24965	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_24985	COG1126	abc transporter atp-binding protein
CFBP5499_24990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_24995	COG4948	Mandelate Racemase Muconate Lactonizing
CFBP5499_25000	COG0006	proline dipeptidase activity
CFBP5499_25005	COG0504	CTP synthase activity
CFBP5499_25035	COG1309	transcriptional regulator
CFBP5499_25050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFBP5499_25070	COG1309	transcriptional regulator
CFBP5499_25075	COG4221	oxidoreductase activity
CFBP5499_25080	COG0604	alcohol dehydrogenase
CFBP5499_25090	COG4106	trans-aconitate 2-methyltransferase activity
CFBP5499_25100	COG1278	Cold shock
CFBP5499_25105	COG1696	Membrane protein involved in D-alanine export
CFBP5499_25165	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFBP5499_25175	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_25180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_25200	COG4302	ethanolamine ammonia-lyase activity
CFBP5499_25225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CFBP5499_25230	COG1349	DNA-binding transcription factor activity
CFBP5499_25235	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_25245	COG0601	transmembrane transport
CFBP5499_25250	COG0747	negative chemotaxis
CFBP5499_25290	COG2994	toxin metabolic process
CFBP5499_25305	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_25310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_25315	COG1802	Transcriptional regulator
CFBP5499_25365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CFBP5499_25425	COG1396	sequence-specific DNA binding
CFBP5499_25490	COG1475	DNA binding
CFBP5499_25495	COG0640	Transcriptional regulator
CFBP5499_25510	COG1126	abc transporter atp-binding protein
CFBP5499_25555	COG0640	Transcriptional regulator
CFBP5499_25570	COG0798	PFAM Bile acid sodium symporter
CFBP5499_25580	COG0431	NADPH-dependent FMN reductase
CFBP5499_25590	COG0730	response to heat
CFBP5499_25630	COG0210	DNA helicase
CFBP5499_25680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_25690	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CFBP5499_25705	COG2197	response regulator
CFBP5499_25715	COG1396	sequence-specific DNA binding
CFBP5499_25775	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_25780	COG1733	regulation of RNA biosynthetic process
CFBP5499_25790	COG0477	Major facilitator Superfamily
CFBP5499_25800	COG1794	racemase activity, acting on amino acids and derivatives
CFBP5499_25810	COG0300	oxidoreductase activity
CFBP5499_25825	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CFBP5499_25830	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFBP5499_25840	COG1605	Chorismate mutase
CFBP5499_25840	COG0287	Prephenate dehydrogenase
CFBP5499_25845	COG0583	DNA-binding transcription factor activity
CFBP5499_25850	COG0300	oxidoreductase activity
CFBP5499_25865	COG1376	ErfK ybiS ycfS ynhG family protein
CFBP5499_25875	COG0251	oxidation-reduction process
CFBP5499_25940	COG0071	Belongs to the small heat shock protein (HSP20) family
CFBP5499_25990	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_26010	COG0747	negative chemotaxis
CFBP5499_26015	COG0601	transmembrane transport
CFBP5499_26020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_26025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_26035	COG3300	MHYT domain
CFBP5499_26035	COG5001	Diguanylate cyclase
CFBP5499_26040	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_26045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5499_26060	COG3920	Histidine kinase
CFBP5499_26075	COG4095	Psort location CytoplasmicMembrane, score
CFBP5499_26085	COG4221	oxidoreductase activity
CFBP5499_26110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFBP5499_26160	COG1414	Transcriptional regulator
CFBP5499_26170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_26185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_26190	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_26195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_26205	COG4175	Glycine betaine
CFBP5499_26205	COG3448	diguanylate cyclase activity
CFBP5499_26210	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_26215	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_26220	COG3938	Belongs to the proline racemase family
CFBP5499_26225	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_26240	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_26245	COG1487	ribonuclease activity
CFBP5499_26255	COG4691	Plasmid stability protein
CFBP5499_26260	COG1487	ribonuclease activity
CFBP5499_26265	COG0784	Response regulator, receiver
CFBP5499_26265	COG4191	Histidine kinase
CFBP5499_26275	COG1278	Cold shock
CFBP5499_26295	COG1609	Transcriptional regulator
CFBP5499_26300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_26305	COG0477	Major facilitator Superfamily
CFBP5499_26315	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_26375	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_26415	COG0583	DNA-binding transcription factor activity
CFBP5499_26425	COG0297	glycogen (starch) synthase activity
CFBP5499_26485	COG4166	transmembrane transport
CFBP5499_26490	COG0601	transmembrane transport
CFBP5499_26495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_26500	COG4172	Belongs to the ABC transporter superfamily
CFBP5499_26505	COG2843	Capsule synthesis protein
CFBP5499_26510	COG2195	Cleaves the N-terminal amino acid of tripeptides
CFBP5499_26525	COG4962	Type ii secretion system protein e
CFBP5499_26540	COG3451	type IV secretory pathway VirB4
CFBP5499_26545	COG5314	conjugation
CFBP5499_26555	COG3846	protein secretion by the type IV secretion system
CFBP5499_26560	COG3701	Conjugal transfer protein
CFBP5499_26580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CFBP5499_26600	COG1309	transcriptional regulator
CFBP5499_26605	COG0667	Aldo Keto reductase
CFBP5499_26625	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP5499_26630	COG2068	MobA-Related Protein
CFBP5499_26645	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_26655	COG0604	alcohol dehydrogenase
CFBP5499_26660	COG1309	transcriptional regulator
CFBP5499_26675	COG0840	transmembrane signaling receptor activity
CFBP5499_26705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_26710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_26720	COG0667	Aldo Keto reductase
CFBP5499_26730	COG3833	ABC-type maltose transport systems, permease component
CFBP5499_26735	COG1175	transmembrane transport
CFBP5499_26740	COG3842	ATPase activity
CFBP5499_26745	COG1414	Transcriptional regulator
CFBP5499_26765	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFBP5499_26780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_26810	COG2801	Transposase and inactivated derivatives
CFBP5499_26825	COG2252	PERMEase
CFBP5499_26830	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_26920	COG5489	Protein of unknown function (DUF736)
CFBP5499_26945	COG1733	regulation of RNA biosynthetic process
CFBP5499_26975	COG1064	alcohol dehydrogenase
CFBP5499_27010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_27025	COG4149	molybdate abc transporter
CFBP5499_27045	COG3842	ATPase activity
CFBP5499_27050	COG1609	Transcriptional regulator
CFBP5499_27060	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_27065	COG0444	Belongs to the ABC transporter superfamily
CFBP5499_27075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_27080	COG0601	transmembrane transport
CFBP5499_27095	COG0747	negative chemotaxis
CFBP5499_27130	COG3005	denitrification pathway
CFBP5499_27140	COG0243	molybdopterin cofactor binding
CFBP5499_27155	COG4459	periplasmic nitrate reductase
CFBP5499_27205	COG3189	MarR family transcriptional regulator
CFBP5499_27210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CFBP5499_27245	COG3256	nitric oxide reductase
CFBP5499_27250	COG0714	Associated with various cellular activities
CFBP5499_27315	COG0300	oxidoreductase activity
CFBP5499_27345	COG4208	sulfate ABC transporter
CFBP5499_27350	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_27360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_27370	COG3842	ATPase activity
CFBP5499_27375	COG0583	DNA-binding transcription factor activity
CFBP5499_27395	COG1309	transcriptional regulator
CFBP5499_27435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_27440	COG1116	anion transmembrane transporter activity
CFBP5499_27440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_27445	COG3665	Urea carboxylase-associated protein
CFBP5499_27470	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFBP5499_27475	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_27485	COG3842	ATPase activity
CFBP5499_27490	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_27495	COG1177	transmembrane transport
CFBP5499_27560	COG3177	Filamentation induced by cAMP protein fic
CFBP5499_27565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CFBP5499_27565	COG2010	Cytochrome c
CFBP5499_27570	COG2080	2 iron, 2 sulfur cluster binding
CFBP5499_27575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CFBP5499_27580	COG0596	Alpha beta hydrolase
CFBP5499_27585	COG3473	Maleate cis-trans isomerase
CFBP5499_27590	COG1335	isochorismatase
CFBP5499_27595	COG2309	aminopeptidase activity
CFBP5499_27600	COG0477	Major facilitator Superfamily
CFBP5499_27605	COG1846	Transcriptional regulator
CFBP5499_27615	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFBP5499_27615	COG3608	succinylglutamate desuccinylase aspartoacylase
CFBP5499_27630	COG1177	transmembrane transport
CFBP5499_27635	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_27640	COG3842	ATPase activity
CFBP5499_27650	COG1609	Transcriptional regulator
CFBP5499_27655	COG1192	Involved in chromosome partitioning
CFBP5499_27660	COG1475	DNA binding
CFBP5499_27665	COG0640	Transcriptional regulator
CFBP5499_27695	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFBP5499_27710	COG1175	transmembrane transport
CFBP5499_27735	COG0840	transmembrane signaling receptor activity
CFBP5499_27735	COG2972	Histidine kinase
CFBP5499_27745	COG1695	Transcriptional regulator
CFBP5499_27755	COG0730	response to heat
CFBP5499_27760	COG0659	secondary active sulfate transmembrane transporter activity
CFBP5499_27770	COG0431	NADPH-dependent FMN reductase
CFBP5499_27780	COG0798	PFAM Bile acid sodium symporter
CFBP5499_27790	COG0640	Transcriptional regulator
CFBP5499_27810	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFBP5499_27815	COG0038	chloride channel
CFBP5499_27820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CFBP5499_27870	COG0515	serine threonine protein kinase
CFBP5499_27920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFBP5499_27925	COG0587	DNA-directed DNA polymerase activity
CFBP5499_27955	COG3831	ATPase activity
CFBP5499_28010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CFBP5499_28025	COG1309	transcriptional regulator
CFBP5499_28030	COG1802	Transcriptional regulator
CFBP5499_28040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFBP5499_28045	COG1012	belongs to the aldehyde dehydrogenase family
CFBP5499_28050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_28060	COG4175	Glycine betaine
CFBP5499_28060	COG3448	diguanylate cyclase activity
CFBP5499_28065	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_28070	COG4176	ABC-type proline glycine betaine transport system permease component
CFBP5499_28075	COG3938	Belongs to the proline racemase family
CFBP5499_28085	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFBP5499_28090	COG2252	PERMEase
CFBP5499_28115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFBP5499_28125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CFBP5499_28165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_28170	COG1116	anion transmembrane transporter activity
CFBP5499_28170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_28185	COG2897	thiosulfate sulfurtransferase activity
CFBP5499_28195	COG3618	amidohydrolase
CFBP5499_28200	COG1879	ABC-type sugar transport system periplasmic component
CFBP5499_28205	COG1172	Belongs to the binding-protein-dependent transport system permease family
CFBP5499_28210	COG1129	ABC transporter
CFBP5499_28215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CFBP5499_28220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_28225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CFBP5499_28230	COG3958	Transketolase
CFBP5499_28235	COG3959	Transketolase, thiamine diphosphate binding domain
CFBP5499_28240	COG1028	Short-chain dehydrogenase reductase Sdr
CFBP5499_28245	COG0583	DNA-binding transcription factor activity
CFBP5499_28265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_28270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CFBP5499_28270	COG1116	anion transmembrane transporter activity
CFBP5499_28275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CFBP5499_28310	COG0300	oxidoreductase activity
CFBP5499_28340	COG3701	Conjugal transfer protein
CFBP5499_28345	COG3846	protein secretion by the type IV secretion system
CFBP5499_28355	COG5314	conjugation
CFBP5499_28360	COG3451	type IV secretory pathway VirB4
CFBP5499_28375	COG4962	Type ii secretion system protein e
CFBP5499_28405	COG4227	nucleotidyltransferase activity
CFBP5499_28410	COG2184	nucleotidyltransferase activity
CFBP5499_28440	COG1475	DNA binding
CFBP5499_28610	COG0784	Response regulator, receiver
CFBP5499_28625	COG2135	peptidase activity
CFBP5499_28650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFBP5499_28655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CFBP5499_28660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CFBP5499_28670	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CFBP5499_28720	COG0741	lytic transglycosylase activity
CFBP5499_28725	COG3838	Conjugal transfer protein Trbc
CFBP5499_28735	COG3451	type IV secretory pathway VirB4
CFBP5499_28740	COG0741	lytic transglycosylase activity
CFBP5499_28770	COG2948	multi-organism process
CFBP5499_28775	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CFBP5499_28805	COG1192	Involved in chromosome partitioning
CFBP5499_28810	COG1475	DNA binding
CFBP5499_28815	COG0640	Transcriptional regulator
CFBP5499_28820	COG1192	Involved in chromosome partitioning
CFBP5499_28825	COG1475	DNA binding
CFBP5499_28830	COG0640	Transcriptional regulator
CFBP5499_28920	COG3932	Exopolysaccharide synthesis, ExoD
CFBP5499_28930	COG1404	Belongs to the peptidase S8 family
CFBP5499_28940	COG1404	Belongs to the peptidase S8 family
CFBP5499_29015	COG3436	PFAM IS66 Orf2 family protein
CFBP5499_29160	COG1902	pentaerythritol trinitrate reductase activity
CFBP5499_29175	COG0667	Aldo Keto reductase
CFBP5499_29205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFBP5499_29210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFBP5499_29275	COG1278	Cold shock
CFBP5499_29320	COG1475	DNA binding
CFBP5499_29345	COG1396	sequence-specific DNA binding
CFBP5499_29365	COG5489	Protein of unknown function (DUF736)
CFBP5499_29375	COG0776	regulation of translation
CFBP5499_29380	COG3831	ATPase activity
CFBP5499_29475	COG1283	sodium-dependent phosphate transmembrane transporter activity
CFBP5499_29490	COG0747	negative chemotaxis
CFBP5499_29500	COG4608	Belongs to the ABC transporter superfamily
CFBP5499_29505	COG0601	transmembrane transport
CFBP5499_29510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_29515	COG0584	glycerophosphoryl diester phosphodiesterase
CFBP5499_29635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFBP5499_29650	COG0747	negative chemotaxis
CFBP5499_29675	COG2222	sugar isomerase
CFBP5499_29695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFBP5499_29700	COG2222	sugar isomerase
CFBP5499_29710	COG1176	ABC-type spermidine putrescine transport system, permease component I
CFBP5499_29715	COG3842	ATPase activity
CFBP5499_29725	COG2188	Transcriptional regulator
CFBP5499_29730	COG0300	oxidoreductase activity
CFBP5499_29735	COG0129	dihydroxy-acid dehydratase activity
CFBP5499_29745	COG1464	Belongs to the NlpA lipoprotein family
CFBP5499_29755	COG2011	ABC-type metal ion transport system permease component
CFBP5499_29780	COG3701	Conjugal transfer protein
CFBP5499_29785	COG3846	protein secretion by the type IV secretion system
CFBP5499_29795	COG5314	conjugation
CFBP5499_29800	COG3451	type IV secretory pathway VirB4
CFBP5499_29815	COG4962	Type ii secretion system protein e