locus-tag	class	description
FY133_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY133_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY133_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY133_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY133_00025	COG1420	regulation of RNA biosynthetic process
FY133_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY133_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY133_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY133_00050	COG1137	ATPase activity
FY133_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY133_00065	COG0616	signal peptide processing
FY133_00070	COG0776	regulation of translation
FY133_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY133_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY133_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY133_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY133_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY133_00115	COG0728	peptidoglycan biosynthetic process
FY133_00125	COG0180	Tryptophanyl-tRNA synthetase
FY133_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY133_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY133_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY133_00165	COG1702	phosphate starvation-inducible protein PhoH
FY133_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY133_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY133_00185	COG1396	sequence-specific DNA binding
FY133_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY133_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY133_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_00210	COG0242	peptide deformylase activity
FY133_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY133_00220	COG0101	tRNA pseudouridine synthase activity
FY133_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY133_00235	COG2171	N-acyltransferase activity
FY133_00245	COG0840	transmembrane signaling receptor activity
FY133_00250	COG1957	nucleoside hydrolase
FY133_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY133_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY133_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY133_00295	COG0706	membrane insertase activity
FY133_00300	COG0594	ribonuclease P activity
FY133_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY133_00310	COG0840	transmembrane signaling receptor activity
FY133_00325	COG2226	methyltransferase
FY133_00330	COG3842	ATPase activity
FY133_00335	COG1175	transmembrane transport
FY133_00340	COG0395	ABC-type sugar transport system, permease component
FY133_00355	COG0427	acetyl-CoA hydrolase
FY133_00365	COG3938	Belongs to the proline racemase family
FY133_00370	COG0418	dihydroorotase activity
FY133_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY133_00400	COG0166	Belongs to the GPI family
FY133_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY133_00410	COG3842	ATPase activity
FY133_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY133_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY133_00425	COG4774	siderophore transport
FY133_00455	COG0582	viral genome integration into host DNA
FY133_00645	COG2326	polyphosphate kinase activity
FY133_00650	COG5002	protein histidine kinase activity
FY133_00655	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY133_00660	COG0573	inorganic phosphate transmembrane transporter activity
FY133_00670	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY133_00675	COG0704	Plays a role in the regulation of phosphate uptake
FY133_00680	COG0745	RESPONSE REGULATOR receiver
FY133_00690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY133_00695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY133_00705	COG2967	ApaG domain
FY133_00720	COG0717	Belongs to the dCTP deaminase family
FY133_00730	COG0582	viral genome integration into host DNA
FY133_00755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY133_00760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_00860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY133_00910	COG0167	dihydroorotate dehydrogenase activity
FY133_00925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY133_00945	COG1959	2 iron, 2 sulfur cluster binding
FY133_00950	COG1201	RNA secondary structure unwinding
FY133_00980	COG1960	acyl-CoA dehydrogenase activity
FY133_00985	COG0183	Belongs to the thiolase family
FY133_00990	COG1024	Enoyl-CoA hydratase
FY133_00990	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY133_01090	COG0582	viral genome integration into host DNA
FY133_01115	COG1320	monovalent cation:proton antiporter activity
FY133_01120	COG2212	antiporter activity
FY133_01125	COG1863	multisubunit Na H antiporter MnhE subunit
FY133_01130	COG0651	ATP synthesis coupled electron transport
FY133_01135	COG1006	Multisubunit Na H antiporter MnhC subunit
FY133_01140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY133_01140	COG2111	Na H antiporter
FY133_01150	COG0840	transmembrane signaling receptor activity
FY133_01160	COG0745	RESPONSE REGULATOR receiver
FY133_01165	COG2198	Histidine kinase
FY133_01165	COG0643	Histidine kinase
FY133_01170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY133_01175	COG2201	protein-glutamate methylesterase activity
FY133_01180	COG0745	RESPONSE REGULATOR receiver
FY133_01185	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY133_01195	COG1766	The M ring may be actively involved in energy transduction
FY133_01200	COG2771	luxR family
FY133_01210	COG2972	Histidine kinase
FY133_01210	COG0840	transmembrane signaling receptor activity
FY133_01215	COG2198	Histidine kinase
FY133_01215	COG2205	protein histidine kinase activity
FY133_01215	COG0784	Response regulator, receiver
FY133_01220	COG1970	mechanosensitive ion channel activity
FY133_01225	COG0436	Aminotransferase
FY133_01240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY133_01245	COG0424	maF-like protein
FY133_01250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY133_01260	COG5328	Belongs to the UPF0262 family
FY133_01265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY133_01275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY133_01295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY133_01305	COG1338	Plays a role in the flagellum-specific transport system
FY133_01315	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY133_01325	COG1706	bacterial-type flagellum-dependent cell motility
FY133_01330	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY133_01335	COG4786	Flagellar basal body rod
FY133_01340	COG1677	Flagellar hook-basal body complex protein FliE
FY133_01345	COG1558	bacterial-type flagellum-dependent cell motility
FY133_01350	COG1815	bacterial-type flagellum-dependent cell motility
FY133_01360	COG1157	protein secretion by the type III secretion system
FY133_01365	COG4786	Flagellar basal body rod
FY133_01375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY133_01380	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY133_01385	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY133_01390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY133_01395	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY133_01415	COG1360	Flagellar Motor Protein
FY133_01440	COG1749	Flagellar hook protein flgE
FY133_01460	COG5443	negative regulation of bacterial-type flagellum assembly
FY133_01465	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY133_01475	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY133_01515	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY133_01520	COG1609	Transcriptional regulator
FY133_01525	COG1653	transport
FY133_01530	COG1175	transmembrane transport
FY133_01535	COG0395	ABC-type sugar transport system, permease component
FY133_01540	COG0366	Alpha amylase catalytic
FY133_01545	COG3842	ATPase activity
FY133_01560	COG0129	dihydroxy-acid dehydratase activity
FY133_01565	COG0363	glucosamine-6-phosphate deaminase activity
FY133_01570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY133_01575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_01585	COG2081	HI0933 family
FY133_01605	COG2224	Isocitrate lyase
FY133_01620	COG3842	ATPase activity
FY133_01625	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_01630	COG1177	transmembrane transport
FY133_01640	COG2205	protein histidine kinase activity
FY133_01650	COG0248	Ppx GppA phosphatase
FY133_01655	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY133_01660	COG0477	Major facilitator Superfamily
FY133_01690	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY133_01695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY133_01705	COG0142	geranyltranstransferase activity
FY133_01730	COG0752	glycyl-tRNA synthetase alpha subunit
FY133_01740	COG1704	LemA family
FY133_01745	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY133_01755	COG0751	glycine-tRNA ligase activity
FY133_01760	COG1683	Conserved Protein
FY133_01765	COG0840	transmembrane signaling receptor activity
FY133_01775	COG0151	Belongs to the GarS family
FY133_01780	COG2183	response to ionizing radiation
FY133_01785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY133_01810	COG0583	DNA-binding transcription factor activity
FY133_01830	COG0306	phosphate transporter
FY133_01840	COG0561	phosphatase activity
FY133_01845	COG0438	transferase activity, transferring glycosyl groups
FY133_01850	COG2186	Transcriptional regulator
FY133_01865	COG0583	DNA-binding transcription factor activity
FY133_01870	COG0277	FAD linked oxidase domain protein
FY133_01875	COG0277	FAD linked oxidase domain protein
FY133_01880	COG0247	lactate metabolic process
FY133_01890	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_01895	COG2818	Glycosylase
FY133_01905	COG2855	membrane
FY133_01910	COG0583	DNA-binding transcription factor activity
FY133_01940	COG0124	histidyl-tRNA synthetase
FY133_01950	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY133_01955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY133_01960	COG2259	Doxx family
FY133_01970	COG0459	protein refolding
FY133_01975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY133_01985	COG0196	riboflavin kinase activity
FY133_01990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY133_02000	COG0590	tRNA wobble adenosine to inosine editing
FY133_02005	COG1187	pseudouridine synthase activity
FY133_02010	COG0742	ribosomal rna small subunit methyltransferase
FY133_02015	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY133_02025	COG0312	modulator of DNA gyrase
FY133_02030	COG0483	inositol monophosphate 1-phosphatase activity
FY133_02040	COG1519	Transferase
FY133_02050	COG1663	tetraacyldisaccharide 4'-kinase activity
FY133_02060	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY133_02065	COG0745	RESPONSE REGULATOR receiver
FY133_02070	COG3300	MHYT domain
FY133_02070	COG5001	Diguanylate cyclase
FY133_02075	COG3386	PFAM SMP-30 Gluconolaconase
FY133_02080	COG0800	Aldolase
FY133_02085	COG3734	2-keto-3-deoxy-galactonokinase
FY133_02090	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_02095	COG1414	Transcriptional regulator
FY133_02100	COG2197	response regulator
FY133_02115	COG0598	Magnesium transport protein CorA
FY133_02120	COG3158	transport of potassium into the cell
FY133_02135	COG0356	it plays a direct role in the translocation of protons across the membrane
FY133_02145	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY133_02150	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY133_02165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY133_02185	COG0009	L-threonylcarbamoyladenylate synthase
FY133_02195	COG4638	Rieske (2fe-2S)
FY133_02220	COG1960	acyl-CoA dehydrogenase activity
FY133_02235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY133_02240	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY133_02245	COG0840	transmembrane signaling receptor activity
FY133_02255	COG1522	sequence-specific DNA binding
FY133_02280	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY133_02285	COG1741	Belongs to the pirin family
FY133_02290	COG1722	exodeoxyribonuclease VII activity
FY133_02295	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY133_02300	COG1268	BioY protein
FY133_02305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY133_02310	COG1122	ATPase activity
FY133_02315	COG3214	Protein conserved in bacteria
FY133_02320	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY133_02320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY133_02325	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY133_02340	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY133_02355	COG0259	pyridoxamine-phosphate oxidase activity
FY133_02385	COG0312	modulator of DNA gyrase
FY133_02400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY133_02405	COG0109	protoheme IX farnesyltransferase activity
FY133_02410	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY133_02425	COG3346	SURF1 family
FY133_02430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY133_02435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY133_02440	COG0328	RNA-DNA hybrid ribonuclease activity
FY133_02450	COG0678	peroxiredoxin activity
FY133_02450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY133_02460	COG1678	Uncharacterized ACR, COG1678
FY133_02465	COG3237	CsbD-like
FY133_02475	COG3300	MHYT domain
FY133_02475	COG5001	Diguanylate cyclase
FY133_02480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY133_02485	COG0612	Peptidase, M16
FY133_02510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY133_02515	COG1802	Transcriptional regulator
FY133_02535	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY133_02540	COG3609	addiction module antidote protein, CC2985 family
FY133_02545	COG3668	Plasmid stabilization system
FY133_02555	COG1194	a g-specific adenine glycosylase
FY133_02570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY133_02575	COG1196	nuclear chromosome segregation
FY133_02580	COG2514	catechol 2,3-dioxygenase activity
FY133_02585	COG0574	Belongs to the PEP-utilizing enzyme family
FY133_02585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY133_02600	COG1823	symporter activity
FY133_02625	COG0579	oxidoreductase
FY133_02640	COG2895	sulfate adenylyltransferase (ATP) activity
FY133_02645	COG0175	sulfate reduction
FY133_02650	COG0175	sulfate reduction
FY133_02655	COG1959	2 iron, 2 sulfur cluster binding
FY133_02660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY133_02665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY133_02670	COG4208	sulfate ABC transporter
FY133_02675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY133_02685	COG2203	Gaf domain
FY133_02685	COG2200	EAL domain
FY133_02685	COG2199	diguanylate cyclase activity
FY133_02695	COG1309	transcriptional regulator
FY133_02700	COG1012	belongs to the aldehyde dehydrogenase family
FY133_02705	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY133_02735	COG0625	glutathione transferase activity
FY133_02745	COG0477	Major facilitator Superfamily
FY133_02755	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY133_02755	COG1793	dna ligase
FY133_02775	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_02780	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_02785	COG1846	Transcriptional regulator
FY133_02790	COG1764	response to oxidative stress
FY133_02805	COG0488	(ABC) transporter
FY133_02840	COG4221	oxidoreductase activity
FY133_02855	COG0433	COG0433 Predicted ATPase
FY133_02865	COG1733	regulation of RNA biosynthetic process
FY133_02870	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY133_02885	COG0656	L-ascorbic acid biosynthetic process
FY133_02890	COG3781	membrane
FY133_02895	COG2378	regulation of single-species biofilm formation
FY133_02905	COG4106	trans-aconitate 2-methyltransferase activity
FY133_02910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY133_02915	COG0840	transmembrane signaling receptor activity
FY133_02920	COG0583	DNA-binding transcription factor activity
FY133_02935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY133_02955	COG3909	cytochrome
FY133_02960	COG2010	Cytochrome c
FY133_02990	COG0789	Transcriptional regulator
FY133_03015	COG4175	Glycine betaine
FY133_03015	COG0517	IMP dehydrogenase activity
FY133_03020	COG4176	ABC-type proline glycine betaine transport system permease component
FY133_03040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_03050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY133_03050	COG2169	Transcriptional regulator
FY133_03060	COG2514	catechol 2,3-dioxygenase activity
FY133_03075	COG1272	protein, Hemolysin III
FY133_03085	COG1280	lysine exporter protein (LysE YggA)
FY133_03090	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY133_03095	COG2111	Na H antiporter
FY133_03095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY133_03100	COG2111	Na H antiporter
FY133_03105	COG1006	Multisubunit Na H antiporter MnhC subunit
FY133_03110	COG0651	ATP synthesis coupled electron transport
FY133_03115	COG1863	multisubunit Na H antiporter MnhE subunit
FY133_03120	COG2212	antiporter activity
FY133_03125	COG1320	monovalent cation:proton antiporter activity
FY133_03130	COG4957	zinc ion binding
FY133_03145	COG2166	iron-sulfur cluster assembly
FY133_03155	COG2205	protein histidine kinase activity
FY133_03200	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY133_03205	COG2983	Belongs to the UPF0260 family
FY133_03215	COG3041	Addiction module toxin RelE StbE family
FY133_03220	COG3077	Addiction module antitoxin, RelB DinJ family
FY133_03225	COG2217	Heavy metal translocating P-type atpase
FY133_03260	COG1621	beta-fructofuranosidase activity
FY133_03265	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY133_03315	COG4695	Portal protein
FY133_03420	COG4235	cytochrome complex assembly
FY133_03425	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY133_03430	COG1138	Cytochrome C-type biogenesis protein
FY133_03435	COG3088	subunit of a heme lyase
FY133_03440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY133_03445	COG0745	RESPONSE REGULATOR receiver
FY133_03450	COG2205	protein histidine kinase activity
FY133_03455	COG3011	Protein conserved in bacteria
FY133_03460	COG3713	MltA-interacting MipA family protein
FY133_03465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY133_03470	COG2205	protein histidine kinase activity
FY133_03470	COG2202	Pas domain
FY133_03480	COG0308	aminopeptidase N
FY133_03485	COG0697	spore germination
FY133_03500	COG0443	Heat shock 70 kDa protein
FY133_03535	COG0604	alcohol dehydrogenase
FY133_03540	COG1733	regulation of RNA biosynthetic process
FY133_03545	COG1968	undecaprenyl-diphosphatase activity
FY133_03550	COG2239	Acts as a magnesium transporter
FY133_03555	COG2814	Major facilitator Superfamily
FY133_03580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY133_03605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY133_03645	COG0741	lytic transglycosylase activity
FY133_03650	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_03655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY133_03660	COG0840	transmembrane signaling receptor activity
FY133_03670	COG1758	RNA polymerase activity
FY133_03690	COG0736	holo-[acyl-carrier-protein] synthase activity
FY133_03695	COG0681	Belongs to the peptidase S26 family
FY133_03700	COG0571	ribonuclease III activity
FY133_03705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY133_03715	COG0784	Response regulator, receiver
FY133_03720	COG1381	Involved in DNA repair and RecF pathway recombination
FY133_03730	COG2226	methyltransferase
FY133_03740	COG1418	mRNA catabolic process
FY133_03750	COG0346	lactoylglutathione lyase activity
FY133_03765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_03770	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY133_03775	COG0668	transmembrane transport
FY133_03785	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY133_03815	COG1742	UPF0060 membrane protein
FY133_03830	COG1183	phosphatidylcholine synthase activity
FY133_03835	COG0688	phosphatidylethanolamine metabolic process
FY133_03840	COG5265	(ABC) transporter
FY133_03880	COG2852	Protein conserved in bacteria
FY133_03885	COG0215	cysteine-tRNA ligase activity
FY133_03890	COG4221	oxidoreductase activity
FY133_03895	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY133_03900	COG1286	toxin biosynthetic process
FY133_03920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY133_03930	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY133_03940	COG5265	(ABC) transporter
FY133_03945	COG0305	Participates in initiation and elongation during chromosome replication
FY133_03965	COG0359	binds to the 23S rRNA
FY133_03975	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY133_03980	COG0360	Binds together with S18 to 16S ribosomal RNA
FY133_03990	COG0667	Aldo Keto reductase
FY133_03995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY133_04005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY133_04010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY133_04020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY133_04025	COG1561	YicC-like family, N-terminal region
FY133_04030	COG0194	GDP metabolic process
FY133_04045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY133_04050	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY133_04060	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY133_04075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY133_04095	COG4251	negative regulation of phosphorylation
FY133_04095	COG3706	GGDEF domain
FY133_04095	COG2203	Gaf domain
FY133_04095	COG5001	Diguanylate cyclase
FY133_04100	COG3300	MHYT domain
FY133_04100	COG5001	Diguanylate cyclase
FY133_04105	COG4191	Histidine kinase
FY133_04110	COG4566	intracellular signal transduction
FY133_04120	COG0488	(ABC) transporter
FY133_04125	COG3706	GGDEF domain
FY133_04135	COG0105	UTP biosynthetic process
FY133_04155	COG0314	molybdopterin synthase activity
FY133_04165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY133_04170	COG0322	excinuclease ABC activity
FY133_04175	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_04190	COG3719	Belongs to the RNase T2 family
FY133_04200	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY133_04205	COG0243	molybdopterin cofactor binding
FY133_04230	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY133_04235	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY133_04245	COG0628	permease
FY133_04255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY133_04260	COG0248	Ppx GppA phosphatase
FY133_04285	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY133_04295	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY133_04300	COG0477	Major facilitator Superfamily
FY133_04305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY133_04315	COG0840	transmembrane signaling receptor activity
FY133_04320	COG0659	secondary active sulfate transmembrane transporter activity
FY133_04330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY133_04335	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY133_04345	COG0113	porphobilinogen synthase activity
FY133_04365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY133_04370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY133_04375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY133_04375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY133_04385	COG1280	lysine exporter protein (LysE YggA)
FY133_04390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY133_04395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY133_04400	COG2814	Major facilitator Superfamily
FY133_04405	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY133_04425	COG0416	fatty acid biosynthetic process
FY133_04430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY133_04435	COG0776	regulation of translation
FY133_04470	COG0601	transmembrane transport
FY133_04475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_04480	COG0444	Belongs to the ABC transporter superfamily
FY133_04490	COG0747	negative chemotaxis
FY133_04500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY133_04505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY133_04520	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY133_04525	COG0583	DNA-binding transcription factor activity
FY133_04530	COG0737	Belongs to the 5'-nucleotidase family
FY133_04550	COG2897	thiosulfate sulfurtransferase activity
FY133_04565	COG0415	Belongs to the DNA photolyase family
FY133_04575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY133_04605	COG3932	Exopolysaccharide synthesis, ExoD
FY133_04610	COG1238	metal cluster binding
FY133_04685	COG1612	heme a metabolic process
FY133_04695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY133_04700	COG0010	Belongs to the arginase family
FY133_04705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY133_04710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY133_04720	COG1832	CoA-binding protein
FY133_04745	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_04750	COG2124	cytochrome p450
FY133_04755	COG2199	diguanylate cyclase activity
FY133_04760	COG0740	serine-type endopeptidase activity
FY133_04765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY133_04770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY133_04780	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY133_04805	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY133_04810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY133_04815	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY133_04825	COG0649	NAD binding
FY133_04835	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY133_04840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY133_04850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY133_04855	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY133_04865	COG0713	ATP synthesis coupled electron transport
FY133_04880	COG1007	ATP synthesis coupled electron transport
FY133_04885	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY133_04885	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY133_04900	COG0442	prolyl-tRNA aminoacylation
FY133_04910	COG1136	(ABC) transporter
FY133_04925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY133_04945	COG0784	Response regulator, receiver
FY133_04955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY133_04960	COG0477	Major facilitator Superfamily
FY133_04975	COG0557	exoribonuclease II activity
FY133_04980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY133_04990	COG0758	DNA mediated transformation
FY133_04995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY133_05005	COG0540	Belongs to the ATCase OTCase family
FY133_05020	COG1960	acyl-CoA dehydrogenase activity
FY133_05025	COG0456	acetyltransferase
FY133_05045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY133_05050	COG2824	Alkylphosphonate utilization operon protein PhnA
FY133_05055	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY133_05060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY133_05065	COG0154	amidase activity
FY133_05070	COG0456	acetyltransferase
FY133_05075	COG3811	Belongs to the UPF0386 family
FY133_05090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY133_05100	COG0456	acetyltransferase
FY133_05120	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY133_05125	COG0439	Biotin carboxylase
FY133_05130	COG0511	ligase activity, forming carbon-carbon bonds
FY133_05135	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY133_05145	COG0436	Aminotransferase
FY133_05165	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_05170	COG1530	ribonuclease E activity
FY133_05180	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY133_05200	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY133_05205	COG0384	phenazine biosynthesis protein PhzF
FY133_05225	COG0633	Ferredoxin
FY133_05240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY133_05245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY133_05255	COG3768	UPF0283 membrane protein
FY133_05260	COG3106	COG3106 Predicted ATPase
FY133_05290	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY133_05325	COG0537	adenosine 5'-monophosphoramidase activity
FY133_05350	COG0052	Belongs to the universal ribosomal protein uS2 family
FY133_05355	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY133_05360	COG0528	UMP kinase activity
FY133_05365	COG0233	cytoplasmic translational termination
FY133_05370	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY133_05380	COG0750	zinc metalloprotease
FY133_05385	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY133_05390	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY133_05395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY133_05400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY133_05405	COG3494	Protein of unknown function (DUF1009)
FY133_05410	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY133_05415	COG2186	Transcriptional regulator
FY133_05425	COG0765	amino acid transport
FY133_05430	COG0765	amino acid transport
FY133_05440	COG0372	Belongs to the citrate synthase family
FY133_05455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY133_05465	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY133_05470	COG0148	phosphopyruvate hydratase activity
FY133_05480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY133_05485	COG0022	dehydrogenase e1 component
FY133_05485	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY133_05490	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY133_05500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY133_05510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY133_05515	COG0697	spore germination
FY133_05530	COG2867	negative regulation of translational initiation
FY133_05535	COG1546	Belongs to the CinA family
FY133_05540	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY133_05540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY133_05550	COG3852	Histidine kinase
FY133_05555	COG2204	response regulator
FY133_05560	COG5000	phosphorelay sensor kinase activity
FY133_05565	COG2204	response regulator
FY133_05570	COG0569	domain protein
FY133_05575	COG1923	regulation of RNA biosynthetic process
FY133_05580	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY133_05585	COG3956	TIGRFAM MazG family protein
FY133_05595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY133_05595	COG1648	precorrin-2 dehydrogenase activity
FY133_05635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY133_05635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY133_05640	COG0509	glycine decarboxylation via glycine cleavage system
FY133_05645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY133_05670	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY133_05675	COG0564	pseudouridine synthase activity
FY133_05695	COG0251	oxidation-reduction process
FY133_05700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY133_05710	COG1671	Belongs to the UPF0178 family
FY133_05725	COG0450	alkyl hydroperoxide reductase
FY133_05735	COG0625	glutathione transferase activity
FY133_05745	COG2801	Transposase and inactivated derivatives
FY133_05750	COG0431	NADPH-dependent FMN reductase
FY133_05760	COG0798	PFAM Bile acid sodium symporter
FY133_05765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY133_05780	COG0321	lipoyl(octanoyl) transferase activity
FY133_05780	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY133_05785	COG0084	hydrolase, TatD family'
FY133_05790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY133_05800	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY133_05850	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY133_05855	COG2095	MarC family integral membrane protein
FY133_05860	COG0517	IMP dehydrogenase activity
FY133_05860	COG0617	tRNA 3'-terminal CCA addition
FY133_05860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY133_05870	COG0629	single-stranded DNA binding
FY133_05875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY133_05885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY133_05905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY133_05910	COG1121	(ABC) transporter
FY133_05930	COG0667	Aldo Keto reductase
FY133_05940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY133_06025	COG2239	Acts as a magnesium transporter
FY133_06030	COG0243	molybdopterin cofactor binding
FY133_06040	COG0242	peptide deformylase activity
FY133_06050	COG2205	protein histidine kinase activity
FY133_06050	COG2202	Pas domain
FY133_06060	COG0321	lipoyl(octanoyl) transferase activity
FY133_06065	COG1064	alcohol dehydrogenase
FY133_06095	COG1862	Preprotein translocase
FY133_06115	COG2124	cytochrome p450
FY133_06130	COG0596	Alpha beta hydrolase
FY133_06140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY133_06145	COG0626	cystathionine gamma-synthase activity
FY133_06150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_06155	COG4597	amino acid ABC transporter
FY133_06160	COG0765	amino acid transport
FY133_06165	COG1126	abc transporter atp-binding protein
FY133_06180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY133_06195	COG0436	Aminotransferase
FY133_06225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY133_06235	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY133_06240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY133_06245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY133_06260	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY133_06265	COG1489	DNA binding
FY133_06270	COG0024	Methionine aminopeptidase
FY133_06275	COG2003	Belongs to the UPF0758 family
FY133_06290	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY133_06315	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY133_06320	COG0546	phosphoglycolate phosphatase activity
FY133_06330	COG0114	fumarate hydratase activity
FY133_06340	COG0504	CTP synthase activity
FY133_06350	COG0149	triose-phosphate isomerase activity
FY133_06360	COG0187	DNA topoisomerase II activity
FY133_06370	COG0740	serine-type endopeptidase activity
FY133_06380	COG0640	Transcriptional regulator
FY133_06385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY133_06390	COG0745	RESPONSE REGULATOR receiver
FY133_06415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY133_06415	COG3264	Mechanosensitive ion channel
FY133_06480	COG1127	ABC transporter
FY133_06485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY133_06490	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_06500	COG0281	malic enzyme
FY133_06500	COG0280	phosphate acetyltransferase
FY133_06510	COG0778	Nitroreductase
FY133_06515	COG0823	Involved in the tonB-independent uptake of proteins
FY133_06530	COG1368	sulfuric ester hydrolase activity
FY133_06550	COG3265	gluconokinase activity
FY133_06555	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY133_06580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY133_06600	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY133_06615	COG0318	PFAM AMP-dependent synthetase and ligase
FY133_06625	COG0512	Glutamine amidotransferase of anthranilate synthase
FY133_06625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY133_06630	COG0343	queuine tRNA-ribosyltransferase activity
FY133_06635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY133_06650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY133_06665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY133_06670	COG0134	indole-3-glycerol-phosphate synthase activity
FY133_06675	COG0315	cyclic pyranopterin monophosphate synthase activity
FY133_06680	COG0303	'Molybdopterin
FY133_06685	COG3706	GGDEF domain
FY133_06695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY133_06695	COG0475	glutathione-regulated potassium exporter activity
FY133_06705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY133_06715	COG2814	Major facilitator Superfamily
FY133_06720	COG0746	molybdenum cofactor guanylyltransferase activity
FY133_06725	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY133_06730	COG0739	heme binding
FY133_06735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY133_06740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY133_06745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY133_06750	COG0805	protein transport
FY133_06755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY133_06760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY133_06765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY133_06770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY133_06775	COG1472	Belongs to the glycosyl hydrolase 3 family
FY133_06785	COG0018	arginyl-trna synthetase
FY133_06790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY133_06815	COG0525	valine-tRNA ligase activity
FY133_06825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY133_06855	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY133_06860	COG1058	Belongs to the CinA family
FY133_06860	COG1546	Belongs to the CinA family
FY133_06865	COG0589	response to stress
FY133_06870	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY133_06880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY133_06890	COG0640	Transcriptional regulator
FY133_06895	COG1914	H( )-stimulated, divalent metal cation uptake system
FY133_06905	COG1132	(ABC) transporter
FY133_06910	COG0628	permease
FY133_06945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY133_06955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY133_06965	COG0302	gtp cyclohydrolase
FY133_06970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY133_06975	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY133_06985	COG0517	IMP dehydrogenase activity
FY133_06985	COG0516	GMP reductase activity
FY133_07020	COG1760	l-serine dehydratase
FY133_07060	COG0583	DNA-binding transcription factor activity
FY133_07075	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY133_07075	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY133_07085	COG0347	Belongs to the P(II) protein family
FY133_07090	COG0174	glutamine synthetase
FY133_07120	COG0697	spore germination
FY133_07130	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY133_07140	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY133_07170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY133_07175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY133_07180	COG2186	Transcriptional regulator
FY133_07190	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY133_07195	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY133_07200	COG3845	ABC transporter
FY133_07205	COG1183	phosphatidylcholine synthase activity
FY133_07210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY133_07215	COG0679	Auxin Efflux Carrier
FY133_07220	COG0785	Cytochrome C biogenesis protein
FY133_07240	COG1278	Cold shock
FY133_07290	COG0577	efflux transmembrane transporter activity
FY133_07290	COG1136	(ABC) transporter
FY133_07295	COG1136	(ABC) transporter
FY133_07295	COG0577	efflux transmembrane transporter activity
FY133_07320	COG2151	metal-sulfur cluster biosynthetic enzyme
FY133_07325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY133_07330	COG0719	Fe-S assembly protein
FY133_07335	COG0396	ATPase activity
FY133_07340	COG0719	Fe-S assembly protein
FY133_07345	COG1104	cysteine desulfurase activity
FY133_07350	COG2945	thiolester hydrolase activity
FY133_07355	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY133_07360	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY133_07370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY133_07375	COG2833	Protein of unknown function (DUF455)
FY133_07380	COG0739	heme binding
FY133_07385	COG0513	Belongs to the DEAD box helicase family
FY133_07410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY133_07420	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY133_07425	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY133_07430	COG0047	phosphoribosylformylglycinamidine synthase activity
FY133_07445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY133_07450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY133_07475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY133_07480	COG2814	Major facilitator Superfamily
FY133_07485	COG0483	inositol monophosphate 1-phosphatase activity
FY133_07490	COG0483	inositol monophosphate 1-phosphatase activity
FY133_07495	COG0037	tRNA processing
FY133_07500	COG2066	Belongs to the glutaminase family
FY133_07505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY133_07510	COG0861	Integral membrane protein TerC family
FY133_07525	COG1280	lysine exporter protein (LysE YggA)
FY133_07535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY133_07540	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY133_07550	COG0538	isocitrate dehydrogenase activity
FY133_07560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY133_07565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY133_07570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_07575	COG2313	pseudouridylate synthase activity
FY133_07585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_07590	COG4215	(ABC) transporter
FY133_07600	COG5425	PFAM Usg family protein
FY133_07610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY133_07615	COG1522	sequence-specific DNA binding
FY133_07620	COG1573	uracil-dna glycosylase
FY133_07630	COG2205	protein histidine kinase activity
FY133_07630	COG2202	Pas domain
FY133_07635	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY133_07640	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY133_07645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY133_07660	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY133_07665	COG0842	Transport permease protein
FY133_07670	COG1131	(ABC) transporter
FY133_07675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY133_07675	COG0730	response to heat
FY133_07695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY133_07700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY133_07720	COG0129	dihydroxy-acid dehydratase activity
FY133_07725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY133_07730	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY133_07740	COG3739	integral membrane protein
FY133_07745	COG0203	ribosomal protein L17
FY133_07750	COG0202	RNA polymerase activity
FY133_07755	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY133_07760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY133_07765	COG0563	adenylate kinase activity
FY133_07770	COG0201	protein transport
FY133_07775	COG0200	Binds to the 23S rRNA
FY133_07780	COG1841	ribosomal large subunit assembly
FY133_07785	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY133_07790	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY133_07795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY133_07800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY133_07805	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY133_07810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY133_07815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY133_07820	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY133_07825	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY133_07830	COG0255	Belongs to the universal ribosomal protein uL29 family
FY133_07835	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY133_07840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY133_07845	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY133_07850	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY133_07855	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY133_07860	COG0089	rRNA binding
FY133_07865	COG0088	Forms part of the polypeptide exit tunnel
FY133_07870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY133_07875	COG0051	transcription antitermination factor activity, RNA binding
FY133_07880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY133_07885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY133_07890	COG0049	tRNA binding
FY133_07895	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY133_07915	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY133_07920	COG0085	RNA polymerase activity
FY133_07925	COG0222	ribosome binding
FY133_07930	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY133_07935	COG0081	regulation of translation
FY133_07940	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY133_07950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY133_07960	COG1086	Polysaccharide biosynthesis protein
FY133_07965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY133_07970	COG0861	Integral membrane protein TerC family
FY133_07975	COG3895	Periplasmic Protein
FY133_07995	COG1132	(ABC) transporter
FY133_08000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY133_08020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY133_08055	COG2198	Histidine kinase
FY133_08055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_08055	COG0784	Response regulator, receiver
FY133_08055	COG2205	protein histidine kinase activity
FY133_08060	COG0784	Response regulator, receiver
FY133_08065	COG2202	Pas domain
FY133_08065	COG3920	Histidine kinase
FY133_08070	COG0784	Response regulator, receiver
FY133_08075	COG4251	negative regulation of phosphorylation
FY133_08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY133_08095	COG1607	acyl-coa hydrolase
FY133_08115	COG2910	NAD(P)H-binding
FY133_08120	COG1733	regulation of RNA biosynthetic process
FY133_08135	COG0556	nucleotide-excision repair
FY133_08145	COG2382	esterase
FY133_08165	COG0484	heat shock protein binding
FY133_08185	COG3706	GGDEF domain
FY133_08205	COG1840	ABC-type Fe3 transport system, periplasmic component
FY133_08210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY133_08225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY133_08235	COG2207	Transcriptional regulator
FY133_08240	COG1064	alcohol dehydrogenase
FY133_08245	COG1252	NADH dehydrogenase
FY133_08250	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY133_08255	COG2197	response regulator
FY133_08260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY133_08295	COG0656	L-ascorbic acid biosynthetic process
FY133_08310	COG0440	acetolactate synthase activity
FY133_08315	COG0028	Belongs to the TPP enzyme family
FY133_08325	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY133_08330	COG3830	Belongs to the UPF0237 family
FY133_08330	COG0560	Phosphoserine phosphatase
FY133_08350	COG0330	HflC and HflK could
FY133_08355	COG0330	HflC and HflK could
FY133_08365	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY133_08405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY133_08445	COG1335	isochorismatase
FY133_08470	COG2264	protein methyltransferase activity
FY133_08475	COG1999	signal sequence binding
FY133_08485	COG0835	chemotaxis
FY133_08495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY133_08500	COG0583	DNA-binding transcription factor activity
FY133_08510	COG1247	-acetyltransferase
FY133_08520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY133_08525	COG0497	DNA recombination
FY133_08530	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY133_08540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY133_08545	COG0849	cell division
FY133_08550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY133_08555	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY133_08560	COG0477	Major facilitator Superfamily
FY133_08565	COG5001	Diguanylate cyclase
FY133_08570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY133_08575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY133_08580	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY133_08590	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY133_08595	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY133_08605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY133_08620	COG0275	rRNA processing
FY133_08625	COG2001	Belongs to the MraZ family
FY133_08630	COG3766	membrane
FY133_08640	COG0754	glutathionylspermidine amidase activity
FY133_08665	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY133_08695	COG4106	trans-aconitate 2-methyltransferase activity
FY133_08715	COG2226	methyltransferase
FY133_08725	COG2267	carboxylic ester hydrolase activity
FY133_08730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY133_08760	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_08765	COG2814	Major facilitator Superfamily
FY133_08795	COG1012	belongs to the aldehyde dehydrogenase family
FY133_08800	COG0174	glutamine synthetase
FY133_08805	COG0531	amino acid
FY133_08815	COG1737	Transcriptional regulator
FY133_08820	COG2182	Extracellular solute-binding protein
FY133_08835	COG3842	ATPase activity
FY133_08900	COG2968	Membrane
FY133_08910	COG0432	Pfam Uncharacterised protein family UPF0047
FY133_08925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY133_08930	COG0358	DNA primase activity
FY133_08955	COG0505	Belongs to the CarA family
FY133_08960	COG0534	Mate efflux family protein
FY133_08975	COG2321	neutral zinc metallopeptidase
FY133_08990	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY133_09000	COG3706	GGDEF domain
FY133_09015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY133_09025	COG1522	sequence-specific DNA binding
FY133_09030	COG0492	ferredoxin-NADP+ reductase activity
FY133_09035	COG0583	DNA-binding transcription factor activity
FY133_09045	COG1902	pentaerythritol trinitrate reductase activity
FY133_09070	COG0387	Pfam Sodium calcium exchanger
FY133_09075	COG0436	Aminotransferase
FY133_09080	COG2200	EAL domain
FY133_09080	COG2199	diguanylate cyclase activity
FY133_09095	COG1278	Cold shock
FY133_09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY133_09110	COG1846	Transcriptional regulator
FY133_09115	COG0745	RESPONSE REGULATOR receiver
FY133_09125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY133_09145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY133_09155	COG1496	oxidoreductase activity
FY133_09170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY133_09180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY133_09195	COG0840	transmembrane signaling receptor activity
FY133_09200	COG1012	belongs to the aldehyde dehydrogenase family
FY133_09205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY133_09210	COG5001	Diguanylate cyclase
FY133_09210	COG3300	MHYT domain
FY133_09215	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY133_09220	COG5001	Diguanylate cyclase
FY133_09230	COG0193	aminoacyl-tRNA hydrolase activity
FY133_09240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY133_09265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY133_09275	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY133_09275	COG2857	Cytochrome c1
FY133_09295	COG1132	(ABC) transporter
FY133_09300	COG1132	(ABC) transporter
FY133_09305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY133_09310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY133_09325	COG0408	coproporphyrinogen oxidase activity
FY133_09340	COG0617	tRNA 3'-terminal CCA addition
FY133_09355	COG0714	Associated with various cellular activities
FY133_09375	COG0454	-acetyltransferase
FY133_09390	COG0477	Major facilitator Superfamily
FY133_09400	COG0435	Glutathione S-transferase
FY133_09405	COG0494	nUDIX hydrolase
FY133_09420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY133_09425	COG3135	benzoate transporter
FY133_09450	COG0740	serine-type endopeptidase activity
FY133_09465	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY133_09470	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY133_09495	COG4175	Glycine betaine
FY133_09515	COG1435	thymidine kinase activity
FY133_09540	COG4771	TonB-dependent receptor
FY133_09540	COG1629	transport
FY133_09550	COG0512	Glutamine amidotransferase of anthranilate synthase
FY133_09550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY133_09565	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY133_09575	COG0366	Alpha amylase catalytic
FY133_09580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_09600	COG1160	GTP binding
FY133_09620	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY133_09630	COG0024	Methionine aminopeptidase
FY133_09640	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_09660	COG0583	DNA-binding transcription factor activity
FY133_09675	COG0402	S-adenosylhomocysteine deaminase activity
FY133_09685	COG1304	FMN binding
FY133_09695	COG1309	transcriptional regulator
FY133_09700	COG1686	Belongs to the peptidase S11 family
FY133_09710	COG2351	hydroxyisourate hydrolase activity
FY133_09715	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY133_09740	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY133_09750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_09750	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY133_09760	COG0513	Belongs to the DEAD box helicase family
FY133_09770	COG2259	Doxx family
FY133_09775	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_09785	COG2308	Evidence 4 Homologs of previously reported genes of
FY133_09795	COG1305	Transglutaminase-like
FY133_09820	COG4214	carbohydrate transport
FY133_09830	COG4213	ABC transporter substrate-binding protein
FY133_09865	COG0840	transmembrane signaling receptor activity
FY133_09880	COG1410	methionine synthase
FY133_09880	COG0646	methionine synthase
FY133_09925	COG1215	transferase activity, transferring glycosyl groups
FY133_09955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY133_09960	COG2346	COG2346, Truncated hemoglobins
FY133_09980	COG1309	transcriptional regulator
FY133_09995	COG0494	nUDIX hydrolase
FY133_10005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_10010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_10040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY133_10045	COG0830	nickel cation binding
FY133_10050	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY133_10065	COG0804	urea catabolic process
FY133_10070	COG1442	glycosyl transferase family 8
FY133_10075	COG3755	Protein conserved in bacteria
FY133_10085	COG0832	Belongs to the urease beta subunit family
FY133_10090	COG3813	Protein conserved in bacteria
FY133_10095	COG0831	urea catabolic process
FY133_10100	COG0829	nickel cation binding
FY133_10120	COG0411	ABC transporter
FY133_10130	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY133_10145	COG0174	glutamine synthetase
FY133_10150	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_10155	COG2198	Histidine kinase
FY133_10155	COG5002	protein histidine kinase activity
FY133_10155	COG0784	Response regulator, receiver
FY133_10170	COG0726	polysaccharide deacetylase
FY133_10205	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY133_10280	COG0564	pseudouridine synthase activity
FY133_10290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY133_10300	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY133_10325	COG0346	lactoylglutathione lyase activity
FY133_10335	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY133_10345	COG2832	Protein of unknown function (DUF454)
FY133_10350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY133_10355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_10360	COG4558	Periplasmic binding protein
FY133_10370	COG3721	Heme iron utilization protein
FY133_10385	COG3655	Transcriptional regulator
FY133_10400	COG3657	addiction module killer protein
FY133_10410	COG2205	protein histidine kinase activity
FY133_10450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_10455	COG4605	iron ion homeostasis
FY133_10460	COG4604	ABC transporter, ATP-binding protein
FY133_10465	COG0783	Belongs to the Dps family
FY133_10480	COG2972	Histidine kinase
FY133_10480	COG0840	transmembrane signaling receptor activity
FY133_10485	COG0656	L-ascorbic acid biosynthetic process
FY133_10490	COG2814	Major facilitator Superfamily
FY133_10500	COG0583	DNA-binding transcription factor activity
FY133_10505	COG0657	acetylesterase activity
FY133_10510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_10530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY133_10535	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY133_10540	COG0288	reversible hydration of carbon dioxide
FY133_10550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY133_10570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY133_10575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY133_10580	COG0778	Nitroreductase
FY133_10585	COG2267	carboxylic ester hydrolase activity
FY133_10590	COG0251	oxidation-reduction process
FY133_10595	COG1335	isochorismatase
FY133_10600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_10610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_10625	COG1175	transmembrane transport
FY133_10630	COG0395	ABC-type sugar transport system, permease component
FY133_10635	COG3842	ATPase activity
FY133_10640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_10650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY133_10665	COG4608	Belongs to the ABC transporter superfamily
FY133_10670	COG0444	Belongs to the ABC transporter superfamily
FY133_10675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_10680	COG0601	transmembrane transport
FY133_10735	COG2159	amidohydrolase
FY133_10740	COG1960	acyl-CoA dehydrogenase activity
FY133_10770	COG0745	RESPONSE REGULATOR receiver
FY133_10780	COG1902	pentaerythritol trinitrate reductase activity
FY133_10780	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY133_10785	COG3842	ATPase activity
FY133_10795	COG1840	ABC-type Fe3 transport system, periplasmic component
FY133_10800	COG1840	ABC-type Fe3 transport system, periplasmic component
FY133_10805	COG0745	RESPONSE REGULATOR receiver
FY133_10815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY133_10820	COG0583	DNA-binding transcription factor activity
FY133_10825	COG1278	Cold shock
FY133_10835	COG0662	Cupin 2, conserved barrel domain protein
FY133_10835	COG2207	Transcriptional regulator
FY133_10850	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_10855	COG0667	Aldo Keto reductase
FY133_10870	COG1309	transcriptional regulator
FY133_10880	COG0604	alcohol dehydrogenase
FY133_10890	COG0667	Aldo Keto reductase
FY133_10910	COG1846	Transcriptional regulator
FY133_10925	COG1136	(ABC) transporter
FY133_10925	COG0577	efflux transmembrane transporter activity
FY133_10930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_10960	COG3209	COG3209 Rhs family protein
FY133_10990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_11015	COG3177	Filamentation induced by cAMP protein fic
FY133_11025	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_11030	COG1414	Transcriptional regulator
FY133_11035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY133_11040	COG3842	ATPase activity
FY133_11045	COG0395	ABC-type sugar transport system, permease component
FY133_11050	COG1175	transmembrane transport
FY133_11060	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_11065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_11070	COG3734	2-keto-3-deoxy-galactonokinase
FY133_11090	COG0583	DNA-binding transcription factor activity
FY133_11100	COG1012	belongs to the aldehyde dehydrogenase family
FY133_11130	COG0667	Aldo Keto reductase
FY133_11140	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_11150	COG0789	Transcriptional regulator
FY133_11165	COG0673	inositol 2-dehydrogenase activity
FY133_11170	COG2267	carboxylic ester hydrolase activity
FY133_11185	COG0583	DNA-binding transcription factor activity
FY133_11190	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_11195	COG0583	DNA-binding transcription factor activity
FY133_11205	COG1063	alcohol dehydrogenase
FY133_11210	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_11265	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_11275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY133_11280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY133_11360	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY133_11365	COG1309	transcriptional regulator
FY133_11370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_11375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY133_11385	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY133_11390	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY133_11410	COG0583	DNA-binding transcription factor activity
FY133_11415	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_11420	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY133_11425	COG4149	molybdate abc transporter
FY133_11430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY133_11445	COG2022	thiamine diphosphate biosynthetic process
FY133_11460	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY133_11470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY133_11480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY133_11500	COG1132	(ABC) transporter
FY133_11505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY133_11550	COG4166	transmembrane transport
FY133_11555	COG0601	transmembrane transport
FY133_11560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_11575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY133_11580	COG3142	Participates in the control of copper homeostasis
FY133_11585	COG2814	Major facilitator Superfamily
FY133_11600	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_11605	COG1737	Transcriptional regulator
FY133_11615	COG3842	ATPase activity
FY133_11625	COG0395	ABC-type sugar transport system, permease component
FY133_11645	COG2188	Transcriptional regulator
FY133_11650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY133_11655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY133_11660	COG1940	carbohydrate kinase activity
FY133_11670	COG0671	phosphoesterase, PA-phosphatase related
FY133_11675	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY133_11680	COG0156	8-amino-7-oxononanoate synthase activity
FY133_11690	COG0729	surface antigen
FY133_11700	COG0835	chemotaxis
FY133_11710	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY133_11715	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY133_11720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY133_11725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY133_11730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY133_11735	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY133_11750	COG4974	Belongs to the 'phage' integrase family
FY133_11775	COG1280	lysine exporter protein (LysE YggA)
FY133_11785	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY133_11790	COG0567	Dehydrogenase, E1 component
FY133_11795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY133_11800	COG0045	succinate-CoA ligase (ADP-forming) activity
FY133_11805	COG0039	L-malate dehydrogenase activity
FY133_11810	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY133_11845	COG2264	protein methyltransferase activity
FY133_11860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY133_11865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY133_11870	COG0181	hydroxymethylbilane synthase activity
FY133_11910	COG1872	DUF167
FY133_11915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY133_11925	COG1217	gtp-binding protein TYPA
FY133_11930	COG0339	signal peptide processing
FY133_11935	COG1846	Transcriptional regulator
FY133_11945	COG0137	argininosuccinate synthase activity
FY133_11955	COG1280	lysine exporter protein (LysE YggA)
FY133_11960	COG1122	ATPase activity
FY133_11965	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY133_11975	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY133_11990	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY133_11995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY133_12000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY133_12010	COG4181	ATPase activity
FY133_12020	COG0670	Belongs to the BI1 family
FY133_12035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY133_12040	COG4133	protoheme IX ABC transporter activity
FY133_12045	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY133_12050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY133_12075	COG2917	probably involved in intracellular septation
FY133_12080	COG0552	protein localization to endoplasmic reticulum
FY133_12085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY133_12090	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY133_12105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY133_12110	COG1605	Chorismate mutase
FY133_12110	COG0287	Prephenate dehydrogenase
FY133_12115	COG0228	four-way junction DNA binding
FY133_12120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY133_12125	COG0336	Belongs to the RNA methyltransferase TrmD family
FY133_12135	COG0335	large ribosomal subunit rRNA binding
FY133_12140	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY133_12145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_12160	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY133_12180	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY133_12200	COG0488	(ABC) transporter
FY133_12210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY133_12220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY133_12225	COG0142	geranyltranstransferase activity
FY133_12230	COG2885	chlorophyll binding
FY133_12235	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY133_12240	COG2223	nitrite transmembrane transporter activity
FY133_12245	COG1349	DNA-binding transcription factor activity
FY133_12250	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY133_12255	COG2197	response regulator
FY133_12260	COG1132	(ABC) transporter
FY133_12270	COG3459	Glycosyltransferase 36 associated
FY133_12275	COG1473	amidohydrolase
FY133_12280	COG0579	oxidoreductase
FY133_12290	COG0129	dihydroxy-acid dehydratase activity
FY133_12295	COG2084	Dehydrogenase
FY133_12300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY133_12305	COG0277	FAD linked oxidase domain protein
FY133_12310	COG2186	Transcriptional regulator
FY133_12320	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY133_12325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY133_12330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY133_12335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY133_12345	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY133_12350	COG0495	leucyl-tRNA aminoacylation
FY133_12365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY133_12370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY133_12385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY133_12390	COG1946	Acyl-CoA thioesterase
FY133_12395	COG0347	Belongs to the P(II) protein family
FY133_12400	COG0004	ammonium transporteR
FY133_12405	COG1674	ftsk spoiiie
FY133_12410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY133_12425	COG0745	RESPONSE REGULATOR receiver
FY133_12435	COG1329	Transcriptional regulator
FY133_12440	COG2902	Dehydrogenase
FY133_12445	COG2270	Major facilitator Superfamily
FY133_12460	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_12475	COG0494	nUDIX hydrolase
FY133_12480	COG2861	carbohydrate metabolic process
FY133_12485	COG0793	Belongs to the peptidase S41A family
FY133_12495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY133_12500	COG0799	negative regulation of ribosome biogenesis
FY133_12505	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY133_12510	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY133_12515	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY133_12520	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY133_12535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY133_12540	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY133_12565	COG0066	3-isopropylmalate dehydratase activity
FY133_12570	COG0473	3-isopropylmalate dehydrogenase activity
FY133_12575	COG1858	cytochrome C peroxidase
FY133_12580	COG1797	cobyrinic acid a,c-diamide synthase activity
FY133_12590	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY133_12655	COG1492	cobalamin metabolic process
FY133_12670	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_12675	COG3254	rhamnose metabolic process
FY133_12685	COG1063	alcohol dehydrogenase
FY133_12710	COG1129	ABC transporter
FY133_12715	COG2186	Transcriptional regulator
FY133_12720	COG2721	sulfolactate sulfo-lyase activity
FY133_12725	COG0138	bifunctional purine biosynthesis protein purh
FY133_12735	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY133_12735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY133_12740	COG0501	Belongs to the peptidase M48B family
FY133_12760	COG0357	Ribosomal RNA small subunit methyltransferase G
FY133_12765	COG0445	tRNA wobble uridine modification
FY133_12770	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY133_12775	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY133_12780	COG1981	membrane
FY133_12785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY133_12790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY133_12795	COG0424	maF-like protein
FY133_12800	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY133_12805	COG0237	dephospho-CoA kinase activity
FY133_12815	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY133_12820	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY133_12830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY133_12855	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY133_12870	COG0135	phosphoribosylanthranilate isomerase activity
FY133_12875	COG0133	tryptophan synthase activity
FY133_12880	COG0159	tryptophan synthase activity
FY133_12885	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY133_12900	COG1074	ATP-dependent DNA helicase activity
FY133_12910	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY133_12915	COG0802	atpase or kinase
FY133_12920	COG2205	protein histidine kinase activity
FY133_12925	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY133_12930	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY133_12935	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY133_12935	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY133_12940	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY133_12945	COG0642	Histidine kinase
FY133_12950	COG0745	RESPONSE REGULATOR receiver
FY133_12955	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY133_12965	COG1652	LysM domain
FY133_12970	COG1072	(Pantothenic acid kinase))
FY133_12975	COG0140	phosphoribosyl-ATP diphosphatase activity
FY133_12980	COG0107	imidazoleglycerol-phosphate synthase activity
FY133_12985	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY133_12990	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY133_13000	COG0131	Imidazoleglycerol-phosphate dehydratase
FY133_13005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY133_13010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY133_13020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY133_13035	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY133_13045	COG1643	Atp-dependent helicase
FY133_13105	COG1072	(Pantothenic acid kinase))
FY133_13115	COG1780	Probably involved in ribonucleotide reductase function
FY133_13135	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY133_13165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_13175	COG2813	Specifically methylates the guanine in position
FY133_13180	COG1185	polyribonucleotide nucleotidyltransferase activity
FY133_13185	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY133_13190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY133_13195	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY133_13200	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY133_13200	COG3064	Membrane
FY133_13215	COG0779	Required for maturation of 30S ribosomal subunits
FY133_13220	COG2814	Major facilitator Superfamily
FY133_13230	COG2951	lytic endotransglycosylase activity
FY133_13235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY133_13245	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY133_13250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY133_13265	COG2816	NAD+ diphosphatase activity
FY133_13270	COG0077	Prephenate dehydratase
FY133_13270	COG1605	Chorismate mutase
FY133_13275	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY133_13280	COG3474	cytochrome
FY133_13290	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY133_13295	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY133_13300	COG1278	Cold shock
FY133_13305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY133_13315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY133_13315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY133_13325	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY133_13355	COG2900	Belongs to the SlyX family
FY133_13365	COG0484	heat shock protein binding
FY133_13370	COG0443	Heat shock 70 kDa protein
FY133_13385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY133_13390	COG1744	ABC transporter substrate-binding protein PnrA-like
FY133_13395	COG3845	ABC transporter
FY133_13400	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY133_13405	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY133_13410	COG0295	cytidine deaminase activity
FY133_13420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY133_13425	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY133_13435	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY133_13440	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY133_13445	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY133_13455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY133_13460	COG1845	cytochrome c oxidase, subunit III
FY133_13465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY133_13470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY133_13475	COG0477	Major facilitator Superfamily
FY133_13480	COG0069	glutamate synthase activity
FY133_13480	COG0067	glutamate synthase
FY133_13480	COG0070	glutamate synthase
FY133_13485	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY133_13500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY133_13510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY133_13540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_13560	COG0848	biopolymer transport protein
FY133_13570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY133_13585	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY133_13590	COG3454	Phosphonate metabolism
FY133_13595	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY133_13600	COG3639	organic phosphonate transmembrane transporter activity
FY133_13605	COG3639	organic phosphonate transmembrane transporter activity
FY133_13610	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY133_13615	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY133_13625	COG4778	phosphonate C-P lyase system protein PhnL
FY133_13630	COG4107	phosphonate C-P lyase system protein PhnK
FY133_13635	COG3627	carbon phosphorus lyase activity
FY133_13640	COG3626	phosphonate metabolism
FY133_13645	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY133_13650	COG3624	Phosphonate C-P lyase system protein PhnG
FY133_13655	COG2188	Transcriptional regulator
FY133_13660	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY133_13665	COG0837	glucose binding
FY133_13670	COG1803	Methylglyoxal synthase
FY133_13675	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY133_13680	COG4166	transmembrane transport
FY133_13685	COG4174	ABC transporter (Permease)
FY133_13690	COG4239	(ABC) transporter, permease
FY133_13695	COG4172	Belongs to the ABC transporter superfamily
FY133_13700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_13705	COG0174	glutamine synthetase
FY133_13710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_13715	COG3265	gluconokinase activity
FY133_13720	COG1174	glycine betaine transport
FY133_13725	COG1125	glycine betaine transport
FY133_13730	COG1174	glycine betaine transport
FY133_13735	COG1732	Glycine betaine
FY133_13745	COG1959	2 iron, 2 sulfur cluster binding
FY133_13750	COG1840	ABC-type Fe3 transport system, periplasmic component
FY133_13760	COG4269	membrane
FY133_13775	COG0697	spore germination
FY133_13790	COG0791	NLP P60 protein
FY133_13800	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY133_13805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY133_13840	COG4964	Belongs to the GSP D family
FY133_13885	COG3422	double-strand break repair
FY133_13890	COG3757	hydrolase, family 25
FY133_13895	COG0697	spore germination
FY133_13900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY133_13915	COG0492	ferredoxin-NADP+ reductase activity
FY133_13930	COG0481	GTPase activity
FY133_13935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY133_13950	COG1396	sequence-specific DNA binding
FY133_13965	COG1917	Cupin 2, conserved barrel domain protein
FY133_13965	COG2169	Transcriptional regulator
FY133_13970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY133_13995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY133_14000	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY133_14005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY133_14015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY133_14020	COG0072	phenylalanine-tRNA ligase activity
FY133_14020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY133_14025	COG0667	Aldo Keto reductase
FY133_14045	COG4977	sequence-specific DNA binding
FY133_14070	COG1570	exodeoxyribonuclease VII activity
FY133_14075	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_14085	COG1846	Transcriptional regulator
FY133_14090	COG0697	spore germination
FY133_14095	COG2309	aminopeptidase activity
FY133_14100	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY133_14105	COG1393	Belongs to the ArsC family
FY133_14120	COG1309	transcriptional regulator
FY133_14130	COG0519	Catalyzes the synthesis of GMP from XMP
FY133_14130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY133_14145	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY133_14175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY133_14185	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY133_14195	COG1968	undecaprenyl-diphosphatase activity
FY133_14210	COG0284	orotidine-5'-phosphate decarboxylase activity
FY133_14220	COG3963	phosphatidate phosphatase activity
FY133_14230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY133_14235	COG0792	nuclease activity
FY133_14250	COG1175	transmembrane transport
FY133_14255	COG0395	ABC-type sugar transport system, permease component
FY133_14260	COG3842	ATPase activity
FY133_14270	COG0189	ligase activity
FY133_14280	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY133_14285	COG1280	lysine exporter protein (LysE YggA)
FY133_14290	COG0756	dUTP diphosphatase activity
FY133_14295	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY133_14300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY133_14315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY133_14320	COG2226	methyltransferase
FY133_14325	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY133_14330	COG1024	Enoyl-CoA hydratase
FY133_14335	COG0268	Binds directly to 16S ribosomal RNA
FY133_14365	COG1278	Cold shock
FY133_14400	COG0411	ABC transporter
FY133_14410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY133_14415	COG1454	alcohol dehydrogenase
FY133_14420	COG0747	negative chemotaxis
FY133_14425	COG0601	transmembrane transport
FY133_14435	COG4608	Belongs to the ABC transporter superfamily
FY133_14440	COG1349	DNA-binding transcription factor activity
FY133_14445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY133_14470	COG4302	ethanolamine ammonia-lyase activity
FY133_14475	COG0025	NhaP-type Na H and K H
FY133_14480	COG4106	trans-aconitate 2-methyltransferase activity
FY133_14495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_14500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_14505	COG0601	transmembrane transport
FY133_14530	COG4172	Belongs to the ABC transporter superfamily
FY133_14535	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY133_14565	COG0596	Alpha beta hydrolase
FY133_14580	COG1764	response to oxidative stress
FY133_14590	COG0596	Alpha beta hydrolase
FY133_14605	COG0783	Belongs to the Dps family
FY133_14610	COG0243	molybdopterin cofactor binding
FY133_14620	COG4566	intracellular signal transduction
FY133_14625	COG4566	intracellular signal transduction
FY133_14635	COG2140	Oxalate decarboxylase
FY133_14655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY133_14665	COG1414	Transcriptional regulator
FY133_14680	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_14700	COG1522	sequence-specific DNA binding
FY133_14725	COG0628	permease
FY133_14735	COG2235	arginine
FY133_14770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY133_14780	COG0702	epimerase
FY133_14785	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY133_14790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_14795	COG0745	RESPONSE REGULATOR receiver
FY133_14800	COG5002	protein histidine kinase activity
FY133_14815	COG2233	PERMEase
FY133_14875	COG0395	ABC-type sugar transport system, permease component
FY133_14880	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_14890	COG3842	ATPase activity
FY133_14925	COG1653	transport
FY133_14935	COG0395	ABC-type sugar transport system, permease component
FY133_14940	COG3842	ATPase activity
FY133_14955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY133_14960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_14965	COG1116	anion transmembrane transporter activity
FY133_14970	COG0395	ABC-type sugar transport system, permease component
FY133_14975	COG1175	transmembrane transport
FY133_15005	COG1609	Transcriptional regulator
FY133_15020	COG1082	Xylose isomerase domain protein TIM barrel
FY133_15035	COG3842	ATPase activity
FY133_15040	COG0395	ABC-type sugar transport system, permease component
FY133_15045	COG1175	transmembrane transport
FY133_15050	COG1653	transport
FY133_15055	COG1309	transcriptional regulator
FY133_15060	COG0673	inositol 2-dehydrogenase activity
FY133_15075	COG0673	inositol 2-dehydrogenase activity
FY133_15080	COG1278	Cold shock
FY133_15090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY133_15110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY133_15115	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY133_15130	COG3842	ATPase activity
FY133_15135	COG0395	ABC-type sugar transport system, permease component
FY133_15140	COG1175	transmembrane transport
FY133_15150	COG3618	amidohydrolase
FY133_15155	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_15160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_15165	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_15170	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY133_15175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY133_15180	COG2186	Transcriptional regulator
FY133_15195	COG0667	Aldo Keto reductase
FY133_15225	COG4977	sequence-specific DNA binding
FY133_15230	COG2223	nitrite transmembrane transporter activity
FY133_15235	COG1609	Transcriptional regulator
FY133_15240	COG1063	alcohol dehydrogenase
FY133_15245	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_15255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_15260	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY133_15265	COG1175	transmembrane transport
FY133_15270	COG0395	ABC-type sugar transport system, permease component
FY133_15285	COG0395	ABC-type sugar transport system, permease component
FY133_15295	COG2182	Extracellular solute-binding protein
FY133_15300	COG0626	cystathionine gamma-synthase activity
FY133_15315	COG0454	-acetyltransferase
FY133_15320	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY133_15330	COG1121	(ABC) transporter
FY133_15335	COG0523	cobalamin synthesis protein
FY133_15350	COG0523	cobalamin synthesis protein
FY133_15355	COG1653	transport
FY133_15360	COG1175	transmembrane transport
FY133_15365	COG0395	ABC-type sugar transport system, permease component
FY133_15370	COG3842	ATPase activity
FY133_15380	COG3047	cAMP biosynthetic process
FY133_15405	COG0583	DNA-binding transcription factor activity
FY133_15410	COG1879	ABC-type sugar transport system periplasmic component
FY133_15415	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_15420	COG1129	ABC transporter
FY133_15430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY133_15435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_15445	COG3257	ureidoglycine aminohydrolase activity
FY133_15455	COG5001	Diguanylate cyclase
FY133_15460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY133_15470	COG0747	negative chemotaxis
FY133_15475	COG0601	transmembrane transport
FY133_15480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_15490	COG4608	Belongs to the ABC transporter superfamily
FY133_15495	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY133_15510	COG0346	lactoylglutathione lyase activity
FY133_15520	COG0129	dihydroxy-acid dehydratase activity
FY133_15525	COG1879	ABC-type sugar transport system periplasmic component
FY133_15530	COG1129	ABC transporter
FY133_15535	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_15540	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_15545	COG2186	Transcriptional regulator
FY133_15560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY133_15565	COG0587	DNA-directed DNA polymerase activity
FY133_15595	COG0673	inositol 2-dehydrogenase activity
FY133_15605	COG3842	ATPase activity
FY133_15610	COG0395	ABC-type sugar transport system, permease component
FY133_15615	COG1175	transmembrane transport
FY133_15620	COG1653	transport
FY133_15630	COG0673	inositol 2-dehydrogenase activity
FY133_15645	COG5001	Diguanylate cyclase
FY133_15660	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY133_15665	COG2894	cell division
FY133_15670	COG0850	regulation of cytokinetic process
FY133_15675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY133_15680	COG2186	Transcriptional regulator
FY133_15685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY133_15695	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY133_15700	COG1063	alcohol dehydrogenase
FY133_15705	COG1312	Catalyzes the dehydration of D-mannonate
FY133_15725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY133_15730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY133_15730	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY133_15735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_15750	COG0625	glutathione transferase activity
FY133_15755	COG4172	Belongs to the ABC transporter superfamily
FY133_15760	COG1921	L-seryl-tRNASec selenium transferase activity
FY133_15775	COG3964	amidohydrolase
FY133_15785	COG0601	transmembrane transport
FY133_15790	COG0747	negative chemotaxis
FY133_15795	COG0438	transferase activity, transferring glycosyl groups
FY133_15830	COG4989	oxidoreductase activity
FY133_15840	COG2188	Transcriptional regulator
FY133_15845	COG3842	ATPase activity
FY133_15850	COG1653	transport
FY133_15855	COG1175	transmembrane transport
FY133_15860	COG0395	ABC-type sugar transport system, permease component
FY133_15865	COG1501	Belongs to the glycosyl hydrolase 31 family
FY133_15875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_15880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY133_15885	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY133_15890	COG0352	thiamine-phosphate diphosphorylase activity
FY133_15895	COG0351	phosphomethylpyrimidine kinase
FY133_15900	COG1522	sequence-specific DNA binding
FY133_15905	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY133_15910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_15925	COG2204	response regulator
FY133_15930	COG4191	Histidine kinase
FY133_15935	COG1301	dicarboxylic acid transport
FY133_15940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY133_15945	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_15955	COG1473	amidohydrolase
FY133_15975	COG1215	transferase activity, transferring glycosyl groups
FY133_15985	COG2942	2-epimerase
FY133_16010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY133_16020	COG2197	response regulator
FY133_16050	COG3307	-O-antigen
FY133_16055	COG1596	polysaccharide export
FY133_16060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY133_16070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY133_16075	COG0840	transmembrane signaling receptor activity
FY133_16080	COG1376	ErfK ybiS ycfS ynhG family protein
FY133_16090	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_16100	COG2094	Belongs to the DNA glycosylase MPG family
FY133_16115	COG1609	Transcriptional regulator
FY133_16120	COG1653	transport
FY133_16135	COG3842	ATPase activity
FY133_16145	COG0673	inositol 2-dehydrogenase activity
FY133_16150	COG0602	queuosine metabolic process
FY133_16155	COG0720	synthase
FY133_16160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY133_16165	COG0673	inositol 2-dehydrogenase activity
FY133_16180	COG0395	ABC-type sugar transport system, permease component
FY133_16185	COG1175	transmembrane transport
FY133_16210	COG0583	DNA-binding transcription factor activity
FY133_16215	COG0281	malic enzyme
FY133_16215	COG0280	phosphate acetyltransferase
FY133_16230	COG0765	amino acid transport
FY133_16235	COG1126	abc transporter atp-binding protein
FY133_16240	COG2079	MmgE PrpD family protein
FY133_16245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_16270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY133_16280	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY133_16285	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY133_16290	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_16295	COG1129	ABC transporter
FY133_16310	COG1473	amidohydrolase
FY133_16315	COG0747	negative chemotaxis
FY133_16330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_16335	COG0601	transmembrane transport
FY133_16340	COG0583	DNA-binding transcription factor activity
FY133_16345	COG1446	asparaginase
FY133_16360	COG0747	negative chemotaxis
FY133_16380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_16385	COG0601	transmembrane transport
FY133_16390	COG2197	response regulator
FY133_16395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY133_16400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY133_16410	COG3842	ATPase activity
FY133_16415	COG0395	ABC-type sugar transport system, permease component
FY133_16420	COG1175	transmembrane transport
FY133_16430	COG0673	inositol 2-dehydrogenase activity
FY133_16435	COG0673	inositol 2-dehydrogenase activity
FY133_16455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_16460	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY133_16480	COG1595	DNA-templated transcription, initiation
FY133_16485	COG1120	ATPase activity
FY133_16490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_16505	COG2226	methyltransferase
FY133_16515	COG1120	ATPase activity
FY133_16520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_16540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY133_16565	COG1012	belongs to the aldehyde dehydrogenase family
FY133_16570	COG0473	3-isopropylmalate dehydrogenase activity
FY133_16575	COG1012	belongs to the aldehyde dehydrogenase family
FY133_16580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_16615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_16620	COG4172	Belongs to the ABC transporter superfamily
FY133_16625	COG1522	sequence-specific DNA binding
FY133_16635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_16650	COG0583	DNA-binding transcription factor activity
FY133_16660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_16665	COG1126	abc transporter atp-binding protein
FY133_16675	COG1473	amidohydrolase
FY133_16680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16690	COG1959	2 iron, 2 sulfur cluster binding
FY133_16700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY133_16705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16735	COG1960	acyl-CoA dehydrogenase activity
FY133_16745	COG0747	negative chemotaxis
FY133_16760	COG0444	Belongs to the ABC transporter superfamily
FY133_16770	COG0667	Aldo Keto reductase
FY133_16780	COG0583	DNA-binding transcription factor activity
FY133_16785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16790	COG4166	transmembrane transport
FY133_16800	COG0747	negative chemotaxis
FY133_16805	COG1473	amidohydrolase
FY133_16810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_16850	COG4608	Belongs to the ABC transporter superfamily
FY133_16855	COG0444	Belongs to the ABC transporter superfamily
FY133_16865	COG0601	transmembrane transport
FY133_16875	COG2186	Transcriptional regulator
FY133_16890	COG0300	oxidoreductase activity
FY133_16900	COG3453	Protein conserved in bacteria
FY133_16900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY133_16905	COG0640	Transcriptional regulator
FY133_16915	COG2391	methyltransferase activity
FY133_16920	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY133_16930	COG0022	dehydrogenase e1 component
FY133_16940	COG1960	acyl-CoA dehydrogenase activity
FY133_16945	COG0183	Belongs to the thiolase family
FY133_16955	COG1960	acyl-CoA dehydrogenase activity
FY133_16960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY133_16980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY133_16985	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY133_16990	COG4952	isomerase
FY133_16995	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_16995	COG3347	Dehydrogenase
FY133_17000	COG1349	DNA-binding transcription factor activity
FY133_17010	COG1129	ABC transporter
FY133_17015	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_17020	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_17025	COG3254	rhamnose metabolic process
FY133_17040	COG2264	protein methyltransferase activity
FY133_17045	COG5001	Diguanylate cyclase
FY133_17060	COG4335	DNA alkylation repair
FY133_17065	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY133_17070	COG4208	sulfate ABC transporter
FY133_17080	COG4150	thiosulfate binding
FY133_17085	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY133_17100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY133_17110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY133_17120	COG1040	competence protein
FY133_17125	COG2226	methyltransferase
FY133_17140	COG0494	nUDIX hydrolase
FY133_17150	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY133_17155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY133_17160	COG0653	protein targeting
FY133_17165	COG0697	spore germination
FY133_17230	COG2244	polysaccharide biosynthetic process
FY133_17245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY133_17255	COG0489	protein tyrosine kinase activity
FY133_17255	COG3206	protein involved in exopolysaccharide biosynthesis
FY133_17270	COG0438	transferase activity, transferring glycosyl groups
FY133_17275	COG0438	transferase activity, transferring glycosyl groups
FY133_17280	COG0438	transferase activity, transferring glycosyl groups
FY133_17295	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY133_17300	COG2273	Hydrolase Family 16
FY133_17300	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY133_17315	COG3842	ATPase activity
FY133_17320	COG3833	ABC-type maltose transport systems, permease component
FY133_17375	COG1396	sequence-specific DNA binding
FY133_17385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY133_17390	COG1129	ABC transporter
FY133_17395	COG4214	carbohydrate transport
FY133_17400	COG4213	ABC transporter substrate-binding protein
FY133_17415	COG0346	lactoylglutathione lyase activity
FY133_17420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY133_17420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY133_17425	COG4770	biotin carboxylase activity
FY133_17440	COG0625	glutathione transferase activity
FY133_17445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY133_17450	COG1396	sequence-specific DNA binding
FY133_17450	COG3800	Transcriptional regulator
FY133_17460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY133_17470	COG0300	oxidoreductase activity
FY133_17480	COG2096	Adenosyltransferase
FY133_17490	COG2086	electron transfer activity
FY133_17500	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY133_17510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY133_17515	COG0165	Argininosuccinate lyase
FY133_17550	COG2884	Cell division ATP-binding protein ftsE
FY133_17570	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY133_17580	COG0287	Prephenate dehydrogenase
FY133_17585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY133_17590	COG2226	methyltransferase
FY133_17595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY133_17615	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY133_17620	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY133_17660	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY133_17665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY133_17675	COG4974	Belongs to the 'phage' integrase family
FY133_17680	COG0825	malonyl-CoA metabolic process
FY133_17685	COG3034	peptidoglycan biosynthetic process
FY133_17690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY133_17690	COG0425	Belongs to the sulfur carrier protein TusA family
FY133_17695	COG0523	cobalamin synthesis protein
FY133_17700	COG1686	Belongs to the peptidase S11 family
FY133_17705	COG1473	amidohydrolase
FY133_17715	COG4953	penicillin-binding protein 1C
FY133_17720	COG2373	Large extracellular alpha-helical protein
FY133_17725	COG2835	tetraacyldisaccharide 4'-kinase activity
FY133_17755	COG0482	sulfurtransferase activity
FY133_17770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY133_17785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY133_17790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY133_17795	COG0037	tRNA processing
FY133_17805	COG2885	chlorophyll binding
FY133_17810	COG0823	Involved in the tonB-independent uptake of proteins
FY133_17830	COG0824	Thioesterase
FY133_17840	COG0494	nUDIX hydrolase
FY133_17855	COG2255	four-way junction helicase activity
FY133_17860	COG0632	four-way junction helicase activity
FY133_17865	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY133_17870	COG0840	transmembrane signaling receptor activity
FY133_17875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_17880	COG0217	transcriptional regulatory protein
FY133_17895	COG1692	metallophosphoesterase
FY133_17905	COG1253	flavin adenine dinucleotide binding
FY133_17945	COG0126	phosphoglycerate kinase activity
FY133_17950	COG3588	fructose-bisphosphate aldolase
FY133_17970	COG0254	rRNA binding
FY133_17975	COG1132	(ABC) transporter
FY133_17995	COG0483	inositol monophosphate 1-phosphatase activity
FY133_18025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY133_18030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY133_18035	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY133_18040	COG0457	Tetratricopeptide repeat
FY133_18045	COG3750	Belongs to the UPF0335 family
FY133_18065	COG0469	pyruvate kinase activity
FY133_18070	COG3108	Peptidase M15
FY133_18075	COG2204	response regulator
FY133_18080	COG1164	Oligoendopeptidase f
FY133_18085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY133_18095	COG5310	Homospermidine synthase
FY133_18105	COG0737	Belongs to the 5'-nucleotidase family
FY133_18110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY133_18115	COG0330	HflC and HflK could
FY133_18145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY133_18150	COG2951	lytic endotransglycosylase activity
FY133_18165	COG2205	protein histidine kinase activity
FY133_18180	COG0067	glutamate synthase
FY133_18180	COG0070	glutamate synthase
FY133_18180	COG0069	glutamate synthase activity
FY133_18195	COG2205	protein histidine kinase activity
FY133_18200	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY133_18205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY133_18210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY133_18220	COG0252	asparaginase activity
FY133_18230	COG1027	Aspartate ammonia-lyase
FY133_18235	COG2186	Transcriptional regulator
FY133_18255	COG1309	transcriptional regulator
FY133_18275	COG4176	ABC-type proline glycine betaine transport system permease component
FY133_18280	COG4175	Glycine betaine
FY133_18280	COG0517	IMP dehydrogenase activity
FY133_18285	COG2986	histidine ammonia-lyase
FY133_18290	COG1609	Transcriptional regulator
FY133_18310	COG1082	Xylose isomerase domain protein TIM barrel
FY133_18315	COG0673	inositol 2-dehydrogenase activity
FY133_18320	COG1082	Xylose isomerase domain protein TIM barrel
FY133_18345	COG3550	peptidyl-serine autophosphorylation
FY133_18390	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FY133_18405	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY133_18430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_18440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_18445	COG0601	transmembrane transport
FY133_18450	COG0747	negative chemotaxis
FY133_18460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY133_18465	COG1454	alcohol dehydrogenase
FY133_18505	COG2307	Protein conserved in bacteria
FY133_18505	COG2308	Evidence 4 Homologs of previously reported genes of
FY133_18520	COG0488	(ABC) transporter
FY133_18525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY133_18530	COG2186	Transcriptional regulator
FY133_18545	COG1175	transmembrane transport
FY133_18550	COG0395	ABC-type sugar transport system, permease component
FY133_18560	COG3842	ATPase activity
FY133_18585	COG1304	FMN binding
FY133_18600	COG1063	alcohol dehydrogenase
FY133_18605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY133_18610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_18620	COG0765	amino acid transport
FY133_18625	COG0765	amino acid transport
FY133_18630	COG4221	oxidoreductase activity
FY133_18635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY133_18640	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_18645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY133_18660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY133_18675	COG0697	spore germination
FY133_18680	COG0697	spore germination
FY133_18685	COG0511	ligase activity, forming carbon-carbon bonds
FY133_18690	COG0439	Biotin carboxylase
FY133_18700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY133_18705	COG1984	allophanate hydrolase subunit 2
FY133_18710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY133_18715	COG3842	ATPase activity
FY133_18725	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY133_18735	COG0436	Aminotransferase
FY133_18750	COG0840	transmembrane signaling receptor activity
FY133_18755	COG1070	Carbohydrate kinase
FY133_18760	COG1830	Aldolase
FY133_18765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY133_18770	COG0667	Aldo Keto reductase
FY133_18780	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_18785	COG1129	ABC transporter
FY133_18790	COG1879	ABC-type sugar transport system periplasmic component
FY133_18825	COG0071	Belongs to the small heat shock protein (HSP20) family
FY133_18840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY133_18855	COG0395	ABC-type sugar transport system, permease component
FY133_18870	COG3842	ATPase activity
FY133_18885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY133_18885	COG1648	precorrin-2 dehydrogenase activity
FY133_18890	COG0243	molybdopterin cofactor binding
FY133_18900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY133_18905	COG1116	anion transmembrane transporter activity
FY133_18910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_18915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY133_18925	COG3707	response regulator
FY133_18930	COG1802	Transcriptional regulator
FY133_18935	COG1914	H( )-stimulated, divalent metal cation uptake system
FY133_18940	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY133_18945	COG4336	lyase activity
FY133_18950	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY133_18955	COG4770	biotin carboxylase activity
FY133_18960	COG0366	Alpha amylase catalytic
FY133_18970	COG4771	TonB-dependent receptor
FY133_18975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY133_18995	COG1414	Transcriptional regulator
FY133_19000	COG1475	DNA binding
FY133_19005	COG1192	Involved in chromosome partitioning
FY133_19035	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY133_19045	COG2986	histidine ammonia-lyase
FY133_19050	COG1228	amidohydrolase
FY133_19055	COG0402	S-adenosylhomocysteine deaminase activity
FY133_19095	COG4172	Belongs to the ABC transporter superfamily
FY133_19100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_19105	COG0601	transmembrane transport
FY133_19110	COG4166	transmembrane transport
FY133_19115	COG0395	ABC-type sugar transport system, permease component
FY133_19130	COG1566	PFAM secretion protein HlyD family protein
FY133_19145	COG2207	Transcriptional regulator
FY133_19150	COG1309	transcriptional regulator
FY133_19155	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_19180	COG1846	Transcriptional regulator
FY133_19185	COG0583	DNA-binding transcription factor activity
FY133_19190	COG2828	Protein conserved in bacteria
FY133_19205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_19220	COG0840	transmembrane signaling receptor activity
FY133_19240	COG1215	transferase activity, transferring glycosyl groups
FY133_19270	COG0583	DNA-binding transcription factor activity
FY133_19275	COG0346	lactoylglutathione lyase activity
FY133_19290	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY133_19310	COG0583	DNA-binding transcription factor activity
FY133_19315	COG0477	Major facilitator Superfamily
FY133_19325	COG2205	protein histidine kinase activity
FY133_19330	COG0745	RESPONSE REGULATOR receiver
FY133_19335	COG0671	phosphoesterase, PA-phosphatase related
FY133_19385	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY133_19390	COG0156	8-amino-7-oxononanoate synthase activity
FY133_19395	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY133_19400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY133_19405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY133_19420	COG0010	Belongs to the arginase family
FY133_19430	COG0697	spore germination
FY133_19435	COG0673	inositol 2-dehydrogenase activity
FY133_19460	COG0477	Major facilitator Superfamily
FY133_19475	COG2194	sulfuric ester hydrolase activity
FY133_19485	COG0583	DNA-binding transcription factor activity
FY133_19490	COG4774	siderophore transport
FY133_19505	COG1120	ATPase activity
FY133_19515	COG3474	cytochrome
FY133_19520	COG2137	regulation of response to DNA damage stimulus
FY133_19525	COG3386	PFAM SMP-30 Gluconolaconase
FY133_19535	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_19540	COG1129	ABC transporter
FY133_19545	COG1879	ABC-type sugar transport system periplasmic component
FY133_19550	COG4585	Histidine kinase
FY133_19555	COG2197	response regulator
FY133_19565	COG2133	pyrroloquinoline quinone binding
FY133_19575	COG0500	methyltransferase
FY133_19580	COG0564	pseudouridine synthase activity
FY133_19595	COG3448	diguanylate cyclase activity
FY133_19595	COG4175	Glycine betaine
FY133_19600	COG4176	ABC-type proline glycine betaine transport system permease component
FY133_19615	COG0784	Response regulator, receiver
FY133_19615	COG4191	Histidine kinase
FY133_19620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY133_19625	COG0489	protein tyrosine kinase activity
FY133_19625	COG3206	protein involved in exopolysaccharide biosynthesis
FY133_19630	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY133_19635	COG1215	transferase activity, transferring glycosyl groups
FY133_19640	COG1215	transferase activity, transferring glycosyl groups
FY133_19645	COG1215	transferase activity, transferring glycosyl groups
FY133_19650	COG0438	transferase activity, transferring glycosyl groups
FY133_19655	COG2273	Hydrolase Family 16
FY133_19660	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY133_19665	COG2244	polysaccharide biosynthetic process
FY133_19670	COG0463	Glycosyl transferase, family 2
FY133_19675	COG2327	Polysaccharide pyruvyl transferase
FY133_19680	COG1215	transferase activity, transferring glycosyl groups
FY133_19700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY133_19705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_19720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY133_19720	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY133_19750	COG1523	belongs to the glycosyl hydrolase 13 family
FY133_19755	COG0033	Phosphoglucomutase
FY133_19760	COG0297	glycogen (starch) synthase activity
FY133_19765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY133_19770	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY133_19775	COG0058	SHG alpha-glucan phosphorylase activity
FY133_19785	COG1794	racemase activity, acting on amino acids and derivatives
FY133_19790	COG1522	sequence-specific DNA binding
FY133_19800	COG2084	Dehydrogenase
FY133_19805	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_19810	COG1063	alcohol dehydrogenase
FY133_19820	COG4988	ABC transporter
FY133_19825	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY133_19835	COG1294	oxidase, subunit
FY133_19865	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY133_19870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY133_19900	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY133_19905	COG0539	negative regulation of cytoplasmic translation
FY133_19935	COG4221	oxidoreductase activity
FY133_19945	COG0747	negative chemotaxis
FY133_19950	COG0601	transmembrane transport
FY133_19955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_19960	COG0444	Belongs to the ABC transporter superfamily
FY133_19965	COG4608	Belongs to the ABC transporter superfamily
FY133_19970	COG0246	Mannitol dehydrogenase
FY133_19985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_20030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY133_20035	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_20050	COG4993	Dehydrogenase
FY133_20055	COG3685	Protein conserved in bacteria
FY133_20085	COG0693	protein deglycase activity
FY133_20105	COG0189	ligase activity
FY133_20110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY133_20115	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY133_20130	COG0435	Glutathione S-transferase
FY133_20135	COG0583	DNA-binding transcription factor activity
FY133_20140	COG1012	belongs to the aldehyde dehydrogenase family
FY133_20145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY133_20150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY133_20155	COG1116	anion transmembrane transporter activity
FY133_20165	COG1522	sequence-specific DNA binding
FY133_20180	COG0784	Response regulator, receiver
FY133_20200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY133_20215	COG0019	diaminopimelate decarboxylase activity
FY133_20230	COG0527	aspartate kinase activity
FY133_20240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY133_20245	COG2890	protein-(glutamine-N5) methyltransferase activity
FY133_20255	COG0542	response to heat
FY133_20260	COG0741	lytic transglycosylase activity
FY133_20260	COG1196	nuclear chromosome segregation
FY133_20260	COG0739	heme binding
FY133_20305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY133_20315	COG1280	lysine exporter protein (LysE YggA)
FY133_20330	COG1309	transcriptional regulator
FY133_20335	COG4221	oxidoreductase activity
FY133_20340	COG1902	pentaerythritol trinitrate reductase activity
FY133_20345	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_20355	COG0604	alcohol dehydrogenase
FY133_20370	COG1278	Cold shock
FY133_20390	COG0753	catalase activity
FY133_20415	COG3920	Histidine kinase
FY133_20435	COG1129	ABC transporter
FY133_20440	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_20445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_20470	COG0667	Aldo Keto reductase
FY133_20485	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_20490	COG1129	ABC transporter
FY133_20495	COG4213	ABC transporter substrate-binding protein
FY133_20515	COG4608	Belongs to the ABC transporter superfamily
FY133_20520	COG0444	Belongs to the ABC transporter superfamily
FY133_20525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_20530	COG0601	transmembrane transport
FY133_20535	COG0747	negative chemotaxis
FY133_20560	COG0765	amino acid transport
FY133_20565	COG4597	amino acid ABC transporter
FY133_20570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_20580	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_20615	COG3077	Addiction module antitoxin, RelB DinJ family
FY133_20630	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY133_20635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY133_20655	COG0625	glutathione transferase activity
FY133_20660	COG4221	oxidoreductase activity
FY133_20670	COG2376	Dihydroxyacetone kinase
FY133_20675	COG1522	sequence-specific DNA binding
FY133_20695	COG0431	NADPH-dependent FMN reductase
FY133_20705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_20715	COG4172	Belongs to the ABC transporter superfamily
FY133_20720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_20740	COG0277	FAD linked oxidase domain protein
FY133_20760	COG0778	Nitroreductase
FY133_20790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY133_20815	COG2318	DinB family
FY133_20820	COG0583	DNA-binding transcription factor activity
FY133_20835	COG1335	isochorismatase
FY133_20860	COG3842	ATPase activity
FY133_20865	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_20870	COG1177	transmembrane transport
FY133_20875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY133_20885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY133_20900	COG1120	ATPase activity
FY133_20905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_20910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_20915	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY133_20920	COG1629	transport
FY133_20920	COG4774	siderophore transport
FY133_20925	COG4702	Belongs to the UPF0303 family
FY133_20945	COG1024	Enoyl-CoA hydratase
FY133_20950	COG1012	belongs to the aldehyde dehydrogenase family
FY133_20955	COG1653	transport
FY133_20960	COG1175	transmembrane transport
FY133_20965	COG0395	ABC-type sugar transport system, permease component
FY133_20970	COG3842	ATPase activity
FY133_20995	COG3474	cytochrome
FY133_21000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY133_21005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY133_21010	COG1845	cytochrome c oxidase, subunit III
FY133_21035	COG1136	(ABC) transporter
FY133_21035	COG0577	efflux transmembrane transporter activity
FY133_21090	COG3842	ATPase activity
FY133_21100	COG1177	transmembrane transport
FY133_21105	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_21120	COG1940	carbohydrate kinase activity
FY133_21140	COG1069	ribulokinase activity
FY133_21145	COG1349	DNA-binding transcription factor activity
FY133_21150	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_21175	COG0395	ABC-type sugar transport system, permease component
FY133_21185	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_21200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY133_21205	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY133_21215	COG0477	Major facilitator Superfamily
FY133_21255	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FY133_21265	COG1733	regulation of RNA biosynthetic process
FY133_21300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY133_21305	COG3938	Belongs to the proline racemase family
FY133_21315	COG4176	ABC-type proline glycine betaine transport system permease component
FY133_21320	COG3448	diguanylate cyclase activity
FY133_21320	COG4175	Glycine betaine
FY133_21330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_21335	COG1012	belongs to the aldehyde dehydrogenase family
FY133_21340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_21350	COG0047	phosphoribosylformylglycinamidine synthase activity
FY133_21355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_21365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY133_21365	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY133_21375	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY133_21395	COG1309	transcriptional regulator
FY133_21410	COG1136	(ABC) transporter
FY133_21425	COG1063	alcohol dehydrogenase
FY133_21435	COG1879	ABC-type sugar transport system periplasmic component
FY133_21445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_21465	COG0477	Major facilitator Superfamily
FY133_21605	COG5001	Diguanylate cyclase
FY133_21605	COG3300	MHYT domain
FY133_21630	COG1253	flavin adenine dinucleotide binding
FY133_21645	COG3842	ATPase activity
FY133_21650	COG0395	ABC-type sugar transport system, permease component
FY133_21655	COG1175	transmembrane transport
FY133_21660	COG1653	transport
FY133_21670	COG0673	inositol 2-dehydrogenase activity
FY133_21675	COG1609	Transcriptional regulator
FY133_21690	COG0583	DNA-binding transcription factor activity
FY133_21700	COG1879	ABC-type sugar transport system periplasmic component
FY133_21705	COG1129	ABC transporter
FY133_21710	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_21715	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_21720	COG1609	Transcriptional regulator
FY133_21730	COG0673	inositol 2-dehydrogenase activity
FY133_21790	COG0714	Associated with various cellular activities
FY133_21795	COG3256	nitric oxide reductase
FY133_21825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY133_21830	COG3189	MarR family transcriptional regulator
FY133_21840	COG0826	peptidase U32
FY133_21865	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY133_21875	COG4459	periplasmic nitrate reductase
FY133_21890	COG0243	molybdopterin cofactor binding
FY133_21900	COG3005	denitrification pathway
FY133_21905	COG0583	DNA-binding transcription factor activity
FY133_21915	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY133_21920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_21935	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_21940	COG3433	isochorismatase activity
FY133_21940	COG1535	isochorismatase
FY133_21945	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY133_21950	COG1169	isochorismate synthase
FY133_21960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY133_21960	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY133_21965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY133_21975	COG2375	cellular response to nickel ion
FY133_21985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_21990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_22000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_22010	COG4774	siderophore transport
FY133_22010	COG1629	transport
FY133_22015	COG1960	acyl-CoA dehydrogenase activity
FY133_22020	COG0583	DNA-binding transcription factor activity
FY133_22025	COG1609	Transcriptional regulator
FY133_22035	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_22045	COG3842	ATPase activity
FY133_22055	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY133_22060	COG0583	DNA-binding transcription factor activity
FY133_22065	COG2814	Major facilitator Superfamily
FY133_22070	COG1473	amidohydrolase
FY133_22075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY133_22085	COG0747	negative chemotaxis
FY133_22090	COG0601	transmembrane transport
FY133_22095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_22100	COG0444	Belongs to the ABC transporter superfamily
FY133_22105	COG4608	Belongs to the ABC transporter superfamily
FY133_22110	COG0583	DNA-binding transcription factor activity
FY133_22115	COG0747	negative chemotaxis
FY133_22120	COG0601	transmembrane transport
FY133_22125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_22130	COG0154	amidase activity
FY133_22135	COG0693	protein deglycase activity
FY133_22145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_22150	COG0601	transmembrane transport
FY133_22160	COG1473	amidohydrolase
FY133_22165	COG4172	Belongs to the ABC transporter superfamily
FY133_22170	COG2390	Transcriptional regulator
FY133_22180	COG1175	transmembrane transport
FY133_22185	COG0395	ABC-type sugar transport system, permease component
FY133_22210	COG1069	ribulokinase activity
FY133_22235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY133_22245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY133_22250	COG1414	Transcriptional regulator
FY133_22255	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_22265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY133_22270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY133_22275	COG1121	(ABC) transporter
FY133_22280	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY133_22290	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY133_22295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY133_22300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY133_22305	COG0471	metal ion transport
FY133_22305	COG3273	potassium ion transport
FY133_22310	COG1253	flavin adenine dinucleotide binding
FY133_22315	COG1309	transcriptional regulator
FY133_22335	COG1609	Transcriptional regulator
FY133_22340	COG1070	Carbohydrate kinase
FY133_22345	COG2115	Belongs to the xylose isomerase family
FY133_22355	COG0778	Nitroreductase
FY133_22360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY133_22365	COG2011	ABC-type metal ion transport system permease component
FY133_22375	COG5001	Diguanylate cyclase
FY133_22375	COG3300	MHYT domain
FY133_22380	COG1054	Belongs to the UPF0176 family
FY133_22390	COG2954	triphosphatase activity
FY133_22395	COG0800	Aldolase
FY133_22415	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY133_22450	COG0523	cobalamin synthesis protein
FY133_22460	COG1846	Transcriptional regulator
FY133_22465	COG1609	Transcriptional regulator
FY133_22470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY133_22480	COG3718	enzyme involved in inositol metabolism
FY133_22490	COG3962	Belongs to the TPP enzyme family
FY133_22495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_22510	COG0411	ABC transporter
FY133_22525	COG0683	leucine binding
FY133_22540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_22550	COG0747	negative chemotaxis
FY133_22555	COG4172	Belongs to the ABC transporter superfamily
FY133_22575	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY133_22580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY133_22585	COG1126	abc transporter atp-binding protein
FY133_22590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_22595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_22600	COG0765	amino acid transport
FY133_22605	COG0765	amino acid transport
FY133_22610	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY133_22615	COG3485	protocatechuate 3,4-dioxygenase
FY133_22620	COG3485	protocatechuate 3,4-dioxygenase
FY133_22625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY133_22635	COG0583	DNA-binding transcription factor activity
FY133_22650	COG1414	Transcriptional regulator
FY133_22660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY133_22665	COG0183	Belongs to the thiolase family
FY133_22670	COG1609	Transcriptional regulator
FY133_22685	COG1082	Xylose isomerase domain protein TIM barrel
FY133_22690	COG0673	inositol 2-dehydrogenase activity
FY133_22700	COG1609	Transcriptional regulator
FY133_22705	COG0395	ABC-type sugar transport system, permease component
FY133_22710	COG1175	transmembrane transport
FY133_22715	COG3842	ATPase activity
FY133_22725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY133_22745	COG2814	Major facilitator Superfamily
FY133_22750	COG4774	siderophore transport
FY133_22755	COG3712	iron ion homeostasis
FY133_22765	COG1940	carbohydrate kinase activity
FY133_22770	COG0584	glycerophosphoryl diester phosphodiesterase
FY133_22775	COG0300	oxidoreductase activity
FY133_22790	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY133_22810	COG0667	Aldo Keto reductase
FY133_22815	COG0583	DNA-binding transcription factor activity
FY133_22825	COG1132	(ABC) transporter
FY133_22830	COG0275	rRNA processing
FY133_22840	COG0673	inositol 2-dehydrogenase activity
FY133_22865	COG3754	Rhamnan synthesis protein F
FY133_22880	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY133_22885	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY133_22890	COG1088	dTDP-glucose 4,6-dehydratase activity
FY133_22895	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY133_22900	COG0210	DNA helicase
FY133_22910	COG1609	Transcriptional regulator
FY133_22915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY133_22915	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY133_22930	COG0395	ABC-type sugar transport system, permease component
FY133_22935	COG3842	ATPase activity
FY133_22945	COG0444	Belongs to the ABC transporter superfamily
FY133_22950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_22955	COG0601	transmembrane transport
FY133_22960	COG2186	Transcriptional regulator
FY133_22980	COG5001	Diguanylate cyclase
FY133_22980	COG3300	MHYT domain
FY133_22985	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_22995	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY133_23005	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY133_23010	COG0306	phosphate transporter
FY133_23015	COG1392	Phosphate transport regulator
FY133_23030	COG1566	PFAM secretion protein HlyD family protein
FY133_23035	COG0745	RESPONSE REGULATOR receiver
FY133_23040	COG2205	protein histidine kinase activity
FY133_23055	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY133_23065	COG4774	siderophore transport
FY133_23075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_23080	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_23085	COG1120	ATPase activity
FY133_23090	COG0583	DNA-binding transcription factor activity
FY133_23100	COG3119	arylsulfatase activity
FY133_23105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY133_23110	COG3842	ATPase activity
FY133_23115	COG0165	Argininosuccinate lyase
FY133_23120	COG0395	ABC-type sugar transport system, permease component
FY133_23125	COG1175	transmembrane transport
FY133_23130	COG2182	Extracellular solute-binding protein
FY133_23135	COG1940	carbohydrate kinase activity
FY133_23160	COG1486	melibiose metabolic process
FY133_23165	COG0747	negative chemotaxis
FY133_23170	COG0601	transmembrane transport
FY133_23175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_23180	COG4172	Belongs to the ABC transporter superfamily
FY133_23185	COG1486	melibiose metabolic process
FY133_23190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY133_23195	COG1129	ABC transporter
FY133_23195	COG0842	Transport permease protein
FY133_23200	COG0842	Transport permease protein
FY133_23215	COG0784	Response regulator, receiver
FY133_23220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY133_23230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_23235	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY133_23250	COG0765	amino acid transport
FY133_23260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_23270	COG3938	Belongs to the proline racemase family
FY133_23285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_23290	COG0765	amino acid transport
FY133_23295	COG0765	amino acid transport
FY133_23305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY133_23320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY133_23350	COG2223	nitrite transmembrane transporter activity
FY133_23355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY133_23365	COG2186	Transcriptional regulator
FY133_23370	COG0747	negative chemotaxis
FY133_23375	COG0601	transmembrane transport
FY133_23380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_23385	COG4172	Belongs to the ABC transporter superfamily
FY133_23390	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_23400	COG2186	Transcriptional regulator
FY133_23405	COG0747	negative chemotaxis
FY133_23410	COG0601	transmembrane transport
FY133_23415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_23420	COG0405	Gamma-glutamyltransferase
FY133_23430	COG0483	inositol monophosphate 1-phosphatase activity
FY133_23440	COG3842	ATPase activity
FY133_23445	COG0395	ABC-type sugar transport system, permease component
FY133_23465	COG3237	CsbD-like
FY133_23475	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY133_23480	COG3181	Tripartite tricarboxylate transporter family receptor
FY133_23485	COG5265	(ABC) transporter
FY133_23490	COG0488	(ABC) transporter
FY133_23515	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY133_23520	COG0110	maltose O-acetyltransferase activity
FY133_23530	COG1063	alcohol dehydrogenase
FY133_23535	COG3284	Transcriptional regulator
FY133_23555	COG1129	ABC transporter
FY133_23560	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_23565	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_23575	COG0572	uridine kinase
FY133_23580	COG1082	Xylose isomerase domain protein TIM barrel
FY133_23605	COG4178	(ABC) transporter
FY133_23640	COG0640	Transcriptional regulator
FY133_23655	COG2274	protein secretion by the type I secretion system
FY133_23670	COG1192	Involved in chromosome partitioning
FY133_23675	COG1475	DNA binding
FY133_23680	COG0640	Transcriptional regulator
FY133_23695	COG1126	abc transporter atp-binding protein
FY133_23700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY133_23705	COG1609	Transcriptional regulator
FY133_23740	COG3239	Fatty acid desaturase
FY133_23750	COG1278	Cold shock
FY133_23825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY133_23825	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY133_23860	COG4191	Histidine kinase
FY133_23865	COG1132	(ABC) transporter
FY133_23875	COG0640	Transcriptional regulator
FY133_23905	COG4977	sequence-specific DNA binding
FY133_23910	COG2211	Major facilitator Superfamily
FY133_23915	COG2807	transmembrane transport
FY133_23920	COG1846	Transcriptional regulator
FY133_23935	COG2814	Major facilitator Superfamily
FY133_23965	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY133_23980	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY133_23985	COG0583	DNA-binding transcription factor activity
FY133_24000	COG0071	Belongs to the small heat shock protein (HSP20) family
FY133_24045	COG3838	Conjugal transfer protein Trbc
FY133_24050	COG3702	type iv secretory pathway
FY133_24055	COG3451	type IV secretory pathway VirB4
FY133_24070	COG3704	protein secretion by the type IV secretion system
FY133_24080	COG3736	Type IV secretory pathway, component VirB8
FY133_24085	COG3504	Conjugal transfer protein
FY133_24090	COG2948	multi-organism process
FY133_24095	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY133_24195	COG3831	ATPase activity
FY133_24210	COG3505	Type IV secretory pathway VirD4
FY133_24235	COG0583	DNA-binding transcription factor activity
FY133_24275	COG0745	RESPONSE REGULATOR receiver
FY133_24315	COG3842	ATPase activity
FY133_24320	COG4208	sulfate ABC transporter
FY133_24325	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_24345	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY133_24350	COG1942	4-Oxalocrotonate Tautomerase
FY133_24360	COG3971	2-oxopent-4-enoate hydratase activity
FY133_24370	COG1414	Transcriptional regulator
FY133_24380	COG1137	ATPase activity
FY133_24395	COG4177	L-phenylalanine transmembrane transporter activity
FY133_24415	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY133_24420	COG1175	transmembrane transport
FY133_24425	COG0395	ABC-type sugar transport system, permease component
FY133_24435	COG0366	Alpha amylase catalytic
FY133_24440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY133_24445	COG1082	Xylose isomerase domain protein TIM barrel
FY133_24450	COG3842	ATPase activity
FY133_24460	COG1940	carbohydrate kinase activity
FY133_24465	COG0395	ABC-type sugar transport system, permease component
FY133_24475	COG2182	Extracellular solute-binding protein
FY133_24480	COG0673	inositol 2-dehydrogenase activity
FY133_24510	COG1126	abc transporter atp-binding protein
FY133_24515	COG0765	amino acid transport
FY133_24520	COG0765	amino acid transport
FY133_24530	COG4608	Belongs to the ABC transporter superfamily
FY133_24540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_24555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY133_24560	COG0583	DNA-binding transcription factor activity
FY133_24565	COG2423	ornithine cyclodeaminase activity
FY133_24575	COG1957	nucleoside hydrolase
FY133_24595	COG1335	isochorismatase
FY133_24600	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_24645	COG0583	DNA-binding transcription factor activity
FY133_24650	COG1902	pentaerythritol trinitrate reductase activity
FY133_24655	COG0583	DNA-binding transcription factor activity
FY133_24660	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_24670	COG1335	isochorismatase
FY133_24675	COG0583	DNA-binding transcription factor activity
FY133_24685	COG1695	Transcriptional regulator
FY133_24765	COG2207	Transcriptional regulator
FY133_24810	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_24825	COG1802	Transcriptional regulator
FY133_24830	COG3485	protocatechuate 3,4-dioxygenase
FY133_24835	COG3971	2-oxopent-4-enoate hydratase activity
FY133_24850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY133_24855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY133_24870	COG1063	alcohol dehydrogenase
FY133_24880	COG1960	acyl-CoA dehydrogenase activity
FY133_24885	COG1024	Enoyl-CoA hydratase
FY133_24895	COG1012	belongs to the aldehyde dehydrogenase family
FY133_24900	COG0477	Major facilitator Superfamily
FY133_24915	COG3706	GGDEF domain
FY133_24935	COG1846	Transcriptional regulator
FY133_24975	COG1012	belongs to the aldehyde dehydrogenase family
FY133_24985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY133_24995	COG3386	PFAM SMP-30 Gluconolaconase
FY133_25000	COG3622	Belongs to the hyi family
FY133_25005	COG2084	Dehydrogenase
FY133_25030	COG1940	carbohydrate kinase activity
FY133_25035	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_25045	COG1129	ABC transporter
FY133_25065	COG0583	DNA-binding transcription factor activity
FY133_25070	COG2271	Major facilitator Superfamily
FY133_25080	COG2272	Belongs to the type-B carboxylesterase lipase family
FY133_25100	COG1129	ABC transporter
FY133_25125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY133_25135	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY133_25170	COG0583	DNA-binding transcription factor activity
FY133_25175	COG1414	Transcriptional regulator
FY133_25185	COG4948	Mandelate Racemase Muconate Lactonizing
FY133_25195	COG3842	ATPase activity
FY133_25200	COG1175	transmembrane transport
FY133_25205	COG0395	ABC-type sugar transport system, permease component
FY133_25215	COG0477	Major facilitator Superfamily
FY133_25250	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY133_25270	COG0747	negative chemotaxis
FY133_25280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_25295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_25305	COG4215	(ABC) transporter
FY133_25360	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY133_25365	COG0251	oxidation-reduction process
FY133_25370	COG3547	Transposase (IS116 IS110 IS902 family)
FY133_25410	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_25415	COG1335	isochorismatase
FY133_25425	COG1309	transcriptional regulator
FY133_25430	COG4604	ABC transporter, ATP-binding protein
FY133_25435	COG4605	iron ion homeostasis
FY133_25440	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY133_25450	COG2132	Multicopper oxidase
FY133_25455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY133_25460	COG4771	TonB-dependent receptor
FY133_25500	COG1695	Transcriptional regulator
FY133_25535	COG2132	Multicopper oxidase
FY133_25540	COG2132	Multicopper oxidase
FY133_25545	COG2132	Multicopper oxidase
FY133_25580	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY133_25600	COG1192	Involved in chromosome partitioning
FY133_25605	COG1475	DNA binding
FY133_25610	COG0640	Transcriptional regulator
FY133_25615	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY133_25645	COG2211	Major facilitator Superfamily
FY133_25695	COG1051	belongs to the nudix hydrolase family
FY133_25735	COG1475	DNA binding
FY133_25760	COG2824	Alkylphosphonate utilization operon protein PhnA
FY133_25785	COG1280	lysine exporter protein (LysE YggA)
FY133_25800	COG5489	Protein of unknown function (DUF736)
FY133_25860	COG1879	ABC-type sugar transport system periplasmic component
FY133_25865	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY133_25885	COG1280	lysine exporter protein (LysE YggA)
FY133_25970	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY133_25985	COG0747	negative chemotaxis
FY133_25990	COG0444	Belongs to the ABC transporter superfamily
FY133_26005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_26010	COG0584	glycerophosphoryl diester phosphodiesterase
FY133_26015	COG0483	inositol monophosphate 1-phosphatase activity
FY133_26080	COG3161	chorismate lyase activity
FY133_26230	COG3436	PFAM IS66 Orf2 family protein
FY133_26310	COG2222	sugar isomerase
FY133_26320	COG0006	proline dipeptidase activity
FY133_26340	COG1177	transmembrane transport
FY133_26345	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY133_26350	COG3842	ATPase activity
FY133_26380	COG3842	ATPase activity
FY133_26385	COG0006	proline dipeptidase activity
FY133_26405	COG0300	oxidoreductase activity
FY133_26410	COG0129	dihydroxy-acid dehydratase activity
FY133_26415	COG0667	Aldo Keto reductase
FY133_26425	COG1028	Short-chain dehydrogenase reductase Sdr
FY133_26435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_26440	COG0601	transmembrane transport
FY133_26445	COG4172	Belongs to the ABC transporter superfamily
FY133_26455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY133_26490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_26525	COG3701	Conjugal transfer protein
FY133_26530	COG3846	protein secretion by the type IV secretion system
FY133_26540	COG5314	conjugation
FY133_26545	COG3451	type IV secretory pathway VirB4
FY133_26560	COG4962	Type ii secretion system protein e
FY133_26570	COG1192	Involved in chromosome partitioning
FY133_26575	COG1475	DNA binding
FY133_26580	COG0640	Transcriptional regulator
FY133_26585	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY133_26685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY133_26700	COG1132	(ABC) transporter
FY133_26705	COG4172	Belongs to the ABC transporter superfamily
FY133_26710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_26720	COG0747	negative chemotaxis
FY133_26730	COG1082	Xylose isomerase domain protein TIM barrel
FY133_26800	COG1475	DNA binding
FY133_26840	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
FY133_26845	COG5489	Protein of unknown function (DUF736)
FY133_26915	COG4172	Belongs to the ABC transporter superfamily
FY133_26920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_26940	COG2072	flavoprotein involved in K transport
FY133_26945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY133_26995	COG0584	glycerophosphoryl diester phosphodiesterase
FY133_27005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_27020	COG0444	Belongs to the ABC transporter superfamily
FY133_27035	COG0747	negative chemotaxis
FY133_27055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY133_27060	COG0601	transmembrane transport
FY133_27075	COG0444	Belongs to the ABC transporter superfamily
FY133_27080	COG0747	negative chemotaxis
FY133_27090	COG2390	Transcriptional regulator
FY133_27135	COG0145	ligase activity
FY133_27145	COG0583	DNA-binding transcription factor activity
FY133_27190	COG3701	Conjugal transfer protein
FY133_27195	COG3846	protein secretion by the type IV secretion system
FY133_27205	COG5314	conjugation
FY133_27210	COG3451	type IV secretory pathway VirB4
FY133_27225	COG4962	Type ii secretion system protein e