locus-tag	class	description
FY136_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY136_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY136_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY136_00025	COG1420	regulation of RNA biosynthetic process
FY136_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY136_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY136_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY136_00050	COG1137	ATPase activity
FY136_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY136_00065	COG0616	signal peptide processing
FY136_00070	COG0776	regulation of translation
FY136_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY136_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY136_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY136_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY136_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY136_00115	COG0728	peptidoglycan biosynthetic process
FY136_00125	COG0180	Tryptophanyl-tRNA synthetase
FY136_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY136_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY136_00165	COG1702	phosphate starvation-inducible protein PhoH
FY136_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY136_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY136_00185	COG1396	sequence-specific DNA binding
FY136_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY136_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY136_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_00210	COG0242	peptide deformylase activity
FY136_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY136_00220	COG0101	tRNA pseudouridine synthase activity
FY136_00225	COG1393	Belongs to the ArsC family
FY136_00235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY136_00240	COG2171	N-acyltransferase activity
FY136_00250	COG0840	transmembrane signaling receptor activity
FY136_00260	COG0071	Belongs to the small heat shock protein (HSP20) family
FY136_00285	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY136_00295	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY136_00300	COG0706	membrane insertase activity
FY136_00305	COG0594	ribonuclease P activity
FY136_00310	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY136_00315	COG0840	transmembrane signaling receptor activity
FY136_00340	COG2226	methyltransferase
FY136_00345	COG3842	ATPase activity
FY136_00350	COG1175	transmembrane transport
FY136_00355	COG0395	ABC-type sugar transport system, permease component
FY136_00370	COG0427	acetyl-CoA hydrolase
FY136_00380	COG3938	Belongs to the proline racemase family
FY136_00385	COG0418	dihydroorotase activity
FY136_00390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY136_00410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY136_00415	COG0166	Belongs to the GPI family
FY136_00420	COG0318	PFAM AMP-dependent synthetase and ligase
FY136_00425	COG3842	ATPase activity
FY136_00430	COG1840	ABC-type Fe3 transport system, periplasmic component
FY136_00435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY136_00440	COG4774	siderophore transport
FY136_00480	COG2326	polyphosphate kinase activity
FY136_00485	COG5002	protein histidine kinase activity
FY136_00490	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY136_00495	COG0573	inorganic phosphate transmembrane transporter activity
FY136_00505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY136_00510	COG0704	Plays a role in the regulation of phosphate uptake
FY136_00515	COG0745	RESPONSE REGULATOR receiver
FY136_00525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY136_00530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY136_00540	COG2967	ApaG domain
FY136_00555	COG0717	Belongs to the dCTP deaminase family
FY136_00680	COG3750	Belongs to the UPF0335 family
FY136_00860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY136_00910	COG0167	dihydroorotate dehydrogenase activity
FY136_00925	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY136_00945	COG1959	2 iron, 2 sulfur cluster binding
FY136_00950	COG1201	RNA secondary structure unwinding
FY136_00980	COG1960	acyl-CoA dehydrogenase activity
FY136_00985	COG0183	Belongs to the thiolase family
FY136_00990	COG1024	Enoyl-CoA hydratase
FY136_00990	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY136_01015	COG1320	monovalent cation:proton antiporter activity
FY136_01020	COG2212	antiporter activity
FY136_01025	COG1863	multisubunit Na H antiporter MnhE subunit
FY136_01030	COG0651	ATP synthesis coupled electron transport
FY136_01035	COG1006	Multisubunit Na H antiporter MnhC subunit
FY136_01040	COG2111	Na H antiporter
FY136_01040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY136_01050	COG0840	transmembrane signaling receptor activity
FY136_01060	COG0745	RESPONSE REGULATOR receiver
FY136_01065	COG0643	Histidine kinase
FY136_01065	COG2198	Histidine kinase
FY136_01070	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY136_01075	COG2201	protein-glutamate methylesterase activity
FY136_01080	COG0745	RESPONSE REGULATOR receiver
FY136_01085	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY136_01095	COG1766	The M ring may be actively involved in energy transduction
FY136_01100	COG2771	luxR family
FY136_01110	COG2972	Histidine kinase
FY136_01110	COG0840	transmembrane signaling receptor activity
FY136_01115	COG0784	Response regulator, receiver
FY136_01115	COG2205	protein histidine kinase activity
FY136_01115	COG2198	Histidine kinase
FY136_01120	COG1970	mechanosensitive ion channel activity
FY136_01125	COG0436	Aminotransferase
FY136_01140	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY136_01145	COG0424	maF-like protein
FY136_01150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY136_01160	COG5328	Belongs to the UPF0262 family
FY136_01165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY136_01175	COG1881	PFAM PEBP family protein
FY136_01185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY136_01200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY136_01215	COG1338	Plays a role in the flagellum-specific transport system
FY136_01225	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY136_01235	COG1706	bacterial-type flagellum-dependent cell motility
FY136_01240	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY136_01245	COG4786	Flagellar basal body rod
FY136_01250	COG1677	Flagellar hook-basal body complex protein FliE
FY136_01255	COG1558	bacterial-type flagellum-dependent cell motility
FY136_01260	COG1815	bacterial-type flagellum-dependent cell motility
FY136_01265	COG1280	lysine exporter protein (LysE YggA)
FY136_01275	COG1157	protein secretion by the type III secretion system
FY136_01280	COG4786	Flagellar basal body rod
FY136_01290	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY136_01295	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY136_01300	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY136_01305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY136_01310	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY136_01320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY136_01330	COG1360	Flagellar Motor Protein
FY136_01355	COG1749	Flagellar hook protein flgE
FY136_01375	COG5443	negative regulation of bacterial-type flagellum assembly
FY136_01380	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY136_01390	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY136_01430	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY136_01435	COG1609	Transcriptional regulator
FY136_01440	COG1653	transport
FY136_01445	COG1175	transmembrane transport
FY136_01450	COG0395	ABC-type sugar transport system, permease component
FY136_01455	COG0366	Alpha amylase catalytic
FY136_01460	COG3842	ATPase activity
FY136_01475	COG0129	dihydroxy-acid dehydratase activity
FY136_01480	COG0363	glucosamine-6-phosphate deaminase activity
FY136_01485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY136_01490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_01500	COG2081	HI0933 family
FY136_01525	COG2224	Isocitrate lyase
FY136_01540	COG3842	ATPase activity
FY136_01545	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_01550	COG1177	transmembrane transport
FY136_01560	COG2205	protein histidine kinase activity
FY136_01570	COG0248	Ppx GppA phosphatase
FY136_01575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY136_01580	COG0477	Major facilitator Superfamily
FY136_01610	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY136_01615	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY136_01625	COG0142	geranyltranstransferase activity
FY136_01650	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY136_01655	COG0752	glycyl-tRNA synthetase alpha subunit
FY136_01660	COG1704	LemA family
FY136_01665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY136_01675	COG0751	glycine-tRNA ligase activity
FY136_01685	COG0840	transmembrane signaling receptor activity
FY136_01695	COG0151	Belongs to the GarS family
FY136_01700	COG2183	response to ionizing radiation
FY136_01705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY136_01715	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY136_01730	COG0583	DNA-binding transcription factor activity
FY136_01750	COG0306	phosphate transporter
FY136_01760	COG0561	phosphatase activity
FY136_01765	COG0438	transferase activity, transferring glycosyl groups
FY136_01770	COG2186	Transcriptional regulator
FY136_01780	COG0583	DNA-binding transcription factor activity
FY136_01785	COG0277	FAD linked oxidase domain protein
FY136_01790	COG0277	FAD linked oxidase domain protein
FY136_01795	COG0247	lactate metabolic process
FY136_01805	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_01810	COG2818	Glycosylase
FY136_01820	COG2855	membrane
FY136_01825	COG0583	DNA-binding transcription factor activity
FY136_01855	COG0124	histidyl-tRNA synthetase
FY136_01865	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY136_01870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY136_01875	COG2259	Doxx family
FY136_01885	COG0459	protein refolding
FY136_01890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY136_01900	COG0196	riboflavin kinase activity
FY136_01905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY136_01915	COG0590	tRNA wobble adenosine to inosine editing
FY136_01920	COG1187	pseudouridine synthase activity
FY136_01925	COG0742	ribosomal rna small subunit methyltransferase
FY136_01930	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY136_01940	COG0312	modulator of DNA gyrase
FY136_01945	COG0483	inositol monophosphate 1-phosphatase activity
FY136_01955	COG1519	Transferase
FY136_01965	COG1663	tetraacyldisaccharide 4'-kinase activity
FY136_01975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY136_01985	COG3300	MHYT domain
FY136_01985	COG5001	Diguanylate cyclase
FY136_01990	COG3386	PFAM SMP-30 Gluconolaconase
FY136_01995	COG0800	Aldolase
FY136_02000	COG3734	2-keto-3-deoxy-galactonokinase
FY136_02005	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_02015	COG2197	response regulator
FY136_02020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_02030	COG0598	Magnesium transport protein CorA
FY136_02035	COG3158	transport of potassium into the cell
FY136_02050	COG0356	it plays a direct role in the translocation of protons across the membrane
FY136_02060	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY136_02065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY136_02075	COG0789	Transcriptional regulator
FY136_02080	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY136_02100	COG0009	L-threonylcarbamoyladenylate synthase
FY136_02110	COG4638	Rieske (2fe-2S)
FY136_02135	COG1960	acyl-CoA dehydrogenase activity
FY136_02150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY136_02160	COG0840	transmembrane signaling receptor activity
FY136_02170	COG1522	sequence-specific DNA binding
FY136_02200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY136_02205	COG1741	Belongs to the pirin family
FY136_02210	COG1722	exodeoxyribonuclease VII activity
FY136_02215	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY136_02220	COG1268	BioY protein
FY136_02225	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY136_02230	COG1122	ATPase activity
FY136_02235	COG3214	Protein conserved in bacteria
FY136_02240	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY136_02240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY136_02245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY136_02265	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY136_02280	COG0259	pyridoxamine-phosphate oxidase activity
FY136_02300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY136_02310	COG0312	modulator of DNA gyrase
FY136_02325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY136_02330	COG0109	protoheme IX farnesyltransferase activity
FY136_02335	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY136_02350	COG3346	SURF1 family
FY136_02355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY136_02360	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY136_02365	COG0328	RNA-DNA hybrid ribonuclease activity
FY136_02375	COG0678	peroxiredoxin activity
FY136_02375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY136_02385	COG1678	Uncharacterized ACR, COG1678
FY136_02390	COG3237	CsbD-like
FY136_02400	COG5001	Diguanylate cyclase
FY136_02400	COG3300	MHYT domain
FY136_02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY136_02410	COG0612	Peptidase, M16
FY136_02425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY136_02430	COG1802	Transcriptional regulator
FY136_02445	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY136_02455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY136_02480	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY136_02485	COG1196	nuclear chromosome segregation
FY136_02490	COG2514	catechol 2,3-dioxygenase activity
FY136_02495	COG0574	Belongs to the PEP-utilizing enzyme family
FY136_02495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY136_02505	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FY136_02515	COG1823	symporter activity
FY136_02655	COG0579	oxidoreductase
FY136_02675	COG2895	sulfate adenylyltransferase (ATP) activity
FY136_02680	COG0175	sulfate reduction
FY136_02685	COG0175	sulfate reduction
FY136_02690	COG1959	2 iron, 2 sulfur cluster binding
FY136_02695	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY136_02700	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY136_02705	COG4208	sulfate ABC transporter
FY136_02710	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY136_02720	COG2200	EAL domain
FY136_02720	COG2203	Gaf domain
FY136_02720	COG2199	diguanylate cyclase activity
FY136_02735	COG1309	transcriptional regulator
FY136_02740	COG1012	belongs to the aldehyde dehydrogenase family
FY136_02745	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY136_02790	COG0477	Major facilitator Superfamily
FY136_02810	COG1793	dna ligase
FY136_02825	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_02830	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_02845	COG1846	Transcriptional regulator
FY136_02850	COG1764	response to oxidative stress
FY136_02890	COG0488	(ABC) transporter
FY136_02905	COG0433	COG0433 Predicted ATPase
FY136_02915	COG1733	regulation of RNA biosynthetic process
FY136_02920	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY136_02935	COG0656	L-ascorbic acid biosynthetic process
FY136_02940	COG3781	membrane
FY136_02945	COG2378	regulation of single-species biofilm formation
FY136_02955	COG4106	trans-aconitate 2-methyltransferase activity
FY136_02960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY136_02965	COG0583	DNA-binding transcription factor activity
FY136_02980	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY136_03000	COG3909	cytochrome
FY136_03005	COG2010	Cytochrome c
FY136_03040	COG0789	Transcriptional regulator
FY136_03065	COG4175	Glycine betaine
FY136_03065	COG0517	IMP dehydrogenase activity
FY136_03070	COG4176	ABC-type proline glycine betaine transport system permease component
FY136_03095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_03105	COG2169	Transcriptional regulator
FY136_03105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY136_03115	COG2514	catechol 2,3-dioxygenase activity
FY136_03130	COG1272	protein, Hemolysin III
FY136_03135	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY136_03140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY136_03140	COG2111	Na H antiporter
FY136_03145	COG2111	Na H antiporter
FY136_03150	COG1006	Multisubunit Na H antiporter MnhC subunit
FY136_03155	COG0651	ATP synthesis coupled electron transport
FY136_03160	COG1863	multisubunit Na H antiporter MnhE subunit
FY136_03165	COG2212	antiporter activity
FY136_03170	COG1320	monovalent cation:proton antiporter activity
FY136_03175	COG4957	zinc ion binding
FY136_03190	COG2166	iron-sulfur cluster assembly
FY136_03200	COG2205	protein histidine kinase activity
FY136_03250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY136_03255	COG2983	Belongs to the UPF0260 family
FY136_03265	COG3041	Addiction module toxin RelE StbE family
FY136_03270	COG3077	Addiction module antitoxin, RelB DinJ family
FY136_03310	COG2814	Major facilitator Superfamily
FY136_03315	COG1621	beta-fructofuranosidase activity
FY136_03320	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY136_03370	COG4695	Portal protein
FY136_03475	COG4235	cytochrome complex assembly
FY136_03480	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY136_03485	COG1138	Cytochrome C-type biogenesis protein
FY136_03490	COG3088	subunit of a heme lyase
FY136_03495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY136_03510	COG3011	Protein conserved in bacteria
FY136_03515	COG3713	MltA-interacting MipA family protein
FY136_03520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY136_03525	COG2202	Pas domain
FY136_03525	COG2205	protein histidine kinase activity
FY136_03535	COG0308	aminopeptidase N
FY136_03540	COG0697	spore germination
FY136_03555	COG0443	Heat shock 70 kDa protein
FY136_03560	COG3447	MASE1 domain protein
FY136_03560	COG5001	Diguanylate cyclase
FY136_03560	COG5002	protein histidine kinase activity
FY136_03565	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_03585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY136_03610	COG1733	regulation of RNA biosynthetic process
FY136_03620	COG1968	undecaprenyl-diphosphatase activity
FY136_03625	COG2239	Acts as a magnesium transporter
FY136_03630	COG2814	Major facilitator Superfamily
FY136_03660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY136_03685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY136_03725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FY136_03730	COG0741	lytic transglycosylase activity
FY136_03735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_03740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY136_03745	COG0840	transmembrane signaling receptor activity
FY136_03755	COG1758	RNA polymerase activity
FY136_03775	COG0736	holo-[acyl-carrier-protein] synthase activity
FY136_03780	COG0681	Belongs to the peptidase S26 family
FY136_03785	COG0571	ribonuclease III activity
FY136_03790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY136_03795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY136_03800	COG0784	Response regulator, receiver
FY136_03805	COG1381	Involved in DNA repair and RecF pathway recombination
FY136_03815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY136_03825	COG1418	mRNA catabolic process
FY136_03835	COG0346	lactoylglutathione lyase activity
FY136_03850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_03855	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY136_03860	COG0668	transmembrane transport
FY136_03870	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY136_03900	COG1742	UPF0060 membrane protein
FY136_03915	COG1183	phosphatidylcholine synthase activity
FY136_03920	COG0688	phosphatidylethanolamine metabolic process
FY136_03925	COG5265	(ABC) transporter
FY136_03970	COG2852	Protein conserved in bacteria
FY136_03975	COG0215	cysteine-tRNA ligase activity
FY136_03980	COG4221	oxidoreductase activity
FY136_03985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY136_03990	COG1286	toxin biosynthetic process
FY136_04010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY136_04020	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY136_04030	COG5265	(ABC) transporter
FY136_04035	COG0305	Participates in initiation and elongation during chromosome replication
FY136_04055	COG0359	binds to the 23S rRNA
FY136_04065	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY136_04070	COG0360	Binds together with S18 to 16S ribosomal RNA
FY136_04080	COG0667	Aldo Keto reductase
FY136_04085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY136_04095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY136_04100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY136_04110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY136_04115	COG1561	YicC-like family, N-terminal region
FY136_04120	COG0194	GDP metabolic process
FY136_04125	COG0400	carboxylic ester hydrolase activity
FY136_04130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY136_04135	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY136_04145	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY136_04160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY136_04180	COG5001	Diguanylate cyclase
FY136_04185	COG4191	Histidine kinase
FY136_04190	COG4566	intracellular signal transduction
FY136_04200	COG0488	(ABC) transporter
FY136_04205	COG3706	GGDEF domain
FY136_04215	COG0105	UTP biosynthetic process
FY136_04235	COG0314	molybdopterin synthase activity
FY136_04245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY136_04250	COG0322	excinuclease ABC activity
FY136_04255	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_04265	COG0625	glutathione transferase activity
FY136_04280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY136_04285	COG0243	molybdopterin cofactor binding
FY136_04305	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY136_04310	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY136_04320	COG0628	permease
FY136_04330	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY136_04335	COG0248	Ppx GppA phosphatase
FY136_04360	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY136_04370	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY136_04375	COG0477	Major facilitator Superfamily
FY136_04380	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY136_04385	COG4452	Inner membrane protein CreD
FY136_04390	COG0840	transmembrane signaling receptor activity
FY136_04395	COG0659	secondary active sulfate transmembrane transporter activity
FY136_04405	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY136_04410	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY136_04420	COG0113	porphobilinogen synthase activity
FY136_04440	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY136_04445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY136_04450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY136_04450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY136_04460	COG1280	lysine exporter protein (LysE YggA)
FY136_04465	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY136_04470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY136_04475	COG2814	Major facilitator Superfamily
FY136_04480	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY136_04500	COG0416	fatty acid biosynthetic process
FY136_04505	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY136_04510	COG0776	regulation of translation
FY136_04545	COG0601	transmembrane transport
FY136_04550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_04555	COG0444	Belongs to the ABC transporter superfamily
FY136_04560	COG4608	Belongs to the ABC transporter superfamily
FY136_04575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY136_04580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY136_04595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY136_04600	COG0583	DNA-binding transcription factor activity
FY136_04610	COG0737	Belongs to the 5'-nucleotidase family
FY136_04635	COG2897	thiosulfate sulfurtransferase activity
FY136_04650	COG0415	Belongs to the DNA photolyase family
FY136_04660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY136_04690	COG3932	Exopolysaccharide synthesis, ExoD
FY136_04695	COG1238	metal cluster binding
FY136_04765	COG1612	heme a metabolic process
FY136_04775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY136_04780	COG0010	Belongs to the arginase family
FY136_04785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY136_04790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY136_04800	COG1832	CoA-binding protein
FY136_04820	COG2124	cytochrome p450
FY136_04825	COG2199	diguanylate cyclase activity
FY136_04830	COG0740	serine-type endopeptidase activity
FY136_04835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY136_04845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY136_04855	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY136_04875	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY136_04880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY136_04885	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY136_04895	COG0649	NAD binding
FY136_04905	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY136_04910	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY136_04920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY136_04925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY136_04935	COG0713	ATP synthesis coupled electron transport
FY136_04950	COG1007	ATP synthesis coupled electron transport
FY136_04970	COG0442	prolyl-tRNA aminoacylation
FY136_04980	COG1136	(ABC) transporter
FY136_04995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY136_05005	COG0784	Response regulator, receiver
FY136_05015	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY136_05020	COG0477	Major facilitator Superfamily
FY136_05035	COG0557	exoribonuclease II activity
FY136_05040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY136_05050	COG0758	DNA mediated transformation
FY136_05055	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY136_05065	COG0540	Belongs to the ATCase OTCase family
FY136_05075	COG1960	acyl-CoA dehydrogenase activity
FY136_05080	COG0456	acetyltransferase
FY136_05110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY136_05115	COG2824	Alkylphosphonate utilization operon protein PhnA
FY136_05120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY136_05125	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY136_05130	COG0154	amidase activity
FY136_05135	COG0456	acetyltransferase
FY136_05140	COG3811	Belongs to the UPF0386 family
FY136_05155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY136_05165	COG0456	acetyltransferase
FY136_05180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY136_05185	COG0439	Biotin carboxylase
FY136_05190	COG0511	ligase activity, forming carbon-carbon bonds
FY136_05195	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY136_05205	COG0436	Aminotransferase
FY136_05225	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_05230	COG1530	ribonuclease E activity
FY136_05240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY136_05260	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY136_05265	COG0384	phenazine biosynthesis protein PhzF
FY136_05280	COG0633	Ferredoxin
FY136_05295	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY136_05300	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY136_05310	COG3768	UPF0283 membrane protein
FY136_05315	COG3106	COG3106 Predicted ATPase
FY136_05340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY136_05375	COG0537	adenosine 5'-monophosphoramidase activity
FY136_05400	COG0052	Belongs to the universal ribosomal protein uS2 family
FY136_05405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY136_05410	COG0528	UMP kinase activity
FY136_05415	COG0233	cytoplasmic translational termination
FY136_05420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY136_05430	COG0750	zinc metalloprotease
FY136_05435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY136_05440	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY136_05445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY136_05450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY136_05455	COG3494	Protein of unknown function (DUF1009)
FY136_05460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY136_05465	COG2186	Transcriptional regulator
FY136_05475	COG0765	amino acid transport
FY136_05480	COG0765	amino acid transport
FY136_05490	COG0372	Belongs to the citrate synthase family
FY136_05505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY136_05515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY136_05520	COG0148	phosphopyruvate hydratase activity
FY136_05530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY136_05535	COG0022	dehydrogenase e1 component
FY136_05535	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY136_05540	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY136_05550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY136_05560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY136_05565	COG0697	spore germination
FY136_05580	COG2867	negative regulation of translational initiation
FY136_05585	COG1546	Belongs to the CinA family
FY136_05590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY136_05590	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY136_05600	COG3852	Histidine kinase
FY136_05605	COG2204	response regulator
FY136_05610	COG5000	phosphorelay sensor kinase activity
FY136_05615	COG2204	response regulator
FY136_05620	COG0569	domain protein
FY136_05625	COG1923	regulation of RNA biosynthetic process
FY136_05630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY136_05635	COG3956	TIGRFAM MazG family protein
FY136_05645	COG1648	precorrin-2 dehydrogenase activity
FY136_05645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY136_05680	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY136_05680	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY136_05685	COG0509	glycine decarboxylation via glycine cleavage system
FY136_05690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY136_05720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY136_05745	COG0251	oxidation-reduction process
FY136_05750	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY136_05760	COG1671	Belongs to the UPF0178 family
FY136_05775	COG0450	alkyl hydroperoxide reductase
FY136_05785	COG0477	Major facilitator Superfamily
FY136_05790	COG0625	glutathione transferase activity
FY136_05795	COG1280	lysine exporter protein (LysE YggA)
FY136_05810	COG2826	transposase and inactivated derivatives, IS30 family
FY136_05815	COG2226	methyltransferase
FY136_05820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_05825	COG0601	transmembrane transport
FY136_05840	COG0583	DNA-binding transcription factor activity
FY136_05855	COG0321	lipoyl(octanoyl) transferase activity
FY136_05855	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY136_05860	COG0084	hydrolase, TatD family'
FY136_05865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY136_05875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY136_05925	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY136_05930	COG2095	MarC family integral membrane protein
FY136_05935	COG0517	IMP dehydrogenase activity
FY136_05935	COG0617	tRNA 3'-terminal CCA addition
FY136_05935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY136_05945	COG0629	single-stranded DNA binding
FY136_05950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY136_05965	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY136_06090	COG0393	Putative heavy-metal-binding
FY136_06235	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY136_06250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY136_06255	COG1121	(ABC) transporter
FY136_06265	COG1609	Transcriptional regulator
FY136_06275	COG0667	Aldo Keto reductase
FY136_06285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY136_06365	COG2239	Acts as a magnesium transporter
FY136_06370	COG0243	molybdopterin cofactor binding
FY136_06380	COG0242	peptide deformylase activity
FY136_06390	COG2205	protein histidine kinase activity
FY136_06390	COG2202	Pas domain
FY136_06405	COG0321	lipoyl(octanoyl) transferase activity
FY136_06410	COG1064	alcohol dehydrogenase
FY136_06440	COG1862	Preprotein translocase
FY136_06460	COG2124	cytochrome p450
FY136_06475	COG0596	Alpha beta hydrolase
FY136_06485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY136_06490	COG0626	cystathionine gamma-synthase activity
FY136_06495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_06500	COG4597	amino acid ABC transporter
FY136_06505	COG0765	amino acid transport
FY136_06510	COG1126	abc transporter atp-binding protein
FY136_06525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY136_06540	COG0436	Aminotransferase
FY136_06570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY136_06580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY136_06585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY136_06590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY136_06605	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY136_06610	COG1489	DNA binding
FY136_06615	COG0024	Methionine aminopeptidase
FY136_06620	COG2003	Belongs to the UPF0758 family
FY136_06635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY136_06650	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY136_06655	COG0546	phosphoglycolate phosphatase activity
FY136_06665	COG0114	fumarate hydratase activity
FY136_06675	COG0504	CTP synthase activity
FY136_06685	COG0149	triose-phosphate isomerase activity
FY136_06695	COG0187	DNA topoisomerase II activity
FY136_06705	COG0740	serine-type endopeptidase activity
FY136_06715	COG0640	Transcriptional regulator
FY136_06720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY136_06725	COG0745	RESPONSE REGULATOR receiver
FY136_06735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY136_06735	COG3264	Mechanosensitive ion channel
FY136_06795	COG1127	ABC transporter
FY136_06800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY136_06805	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_06815	COG0281	malic enzyme
FY136_06815	COG0280	phosphate acetyltransferase
FY136_06825	COG0778	Nitroreductase
FY136_06830	COG0823	Involved in the tonB-independent uptake of proteins
FY136_06845	COG1368	sulfuric ester hydrolase activity
FY136_06870	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY136_06890	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY136_06915	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY136_06940	COG0512	Glutamine amidotransferase of anthranilate synthase
FY136_06940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY136_06945	COG0343	queuine tRNA-ribosyltransferase activity
FY136_06950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY136_06965	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY136_06980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY136_06985	COG0134	indole-3-glycerol-phosphate synthase activity
FY136_06990	COG0315	cyclic pyranopterin monophosphate synthase activity
FY136_06995	COG0303	'Molybdopterin
FY136_07000	COG3706	GGDEF domain
FY136_07015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY136_07015	COG0475	glutathione-regulated potassium exporter activity
FY136_07025	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY136_07030	COG0697	spore germination
FY136_07035	COG2814	Major facilitator Superfamily
FY136_07040	COG0746	molybdenum cofactor guanylyltransferase activity
FY136_07045	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY136_07050	COG0739	heme binding
FY136_07055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY136_07060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY136_07065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY136_07070	COG0805	protein transport
FY136_07075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY136_07080	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY136_07085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY136_07090	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY136_07095	COG1472	Belongs to the glycosyl hydrolase 3 family
FY136_07105	COG0018	arginyl-trna synthetase
FY136_07110	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY136_07115	COG0316	Belongs to the HesB IscA family
FY136_07140	COG0525	valine-tRNA ligase activity
FY136_07150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY136_07175	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY136_07180	COG1546	Belongs to the CinA family
FY136_07180	COG1058	Belongs to the CinA family
FY136_07185	COG0589	response to stress
FY136_07190	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY136_07195	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY136_07205	COG1914	H( )-stimulated, divalent metal cation uptake system
FY136_07220	COG1132	(ABC) transporter
FY136_07225	COG0628	permease
FY136_07260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY136_07270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY136_07280	COG0302	gtp cyclohydrolase
FY136_07285	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY136_07290	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY136_07300	COG0516	GMP reductase activity
FY136_07300	COG0517	IMP dehydrogenase activity
FY136_07335	COG1760	l-serine dehydratase
FY136_07370	COG0583	DNA-binding transcription factor activity
FY136_07385	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY136_07385	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY136_07390	COG0347	Belongs to the P(II) protein family
FY136_07395	COG0174	glutamine synthetase
FY136_07425	COG0697	spore germination
FY136_07435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY136_07445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY136_07475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY136_07480	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY136_07485	COG2186	Transcriptional regulator
FY136_07495	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY136_07500	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY136_07505	COG3845	ABC transporter
FY136_07510	COG1183	phosphatidylcholine synthase activity
FY136_07515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY136_07520	COG0679	Auxin Efflux Carrier
FY136_07525	COG0785	Cytochrome C biogenesis protein
FY136_07545	COG4221	oxidoreductase activity
FY136_07565	COG1278	Cold shock
FY136_07620	COG1136	(ABC) transporter
FY136_07620	COG0577	efflux transmembrane transporter activity
FY136_07625	COG0577	efflux transmembrane transporter activity
FY136_07625	COG1136	(ABC) transporter
FY136_07650	COG2151	metal-sulfur cluster biosynthetic enzyme
FY136_07655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY136_07660	COG0719	Fe-S assembly protein
FY136_07665	COG0396	ATPase activity
FY136_07675	COG0719	Fe-S assembly protein
FY136_07680	COG1104	cysteine desulfurase activity
FY136_07685	COG2945	thiolester hydrolase activity
FY136_07690	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY136_07695	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY136_07705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY136_07710	COG2833	Protein of unknown function (DUF455)
FY136_07715	COG0739	heme binding
FY136_07720	COG0513	Belongs to the DEAD box helicase family
FY136_07745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY136_07755	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY136_07760	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY136_07765	COG0047	phosphoribosylformylglycinamidine synthase activity
FY136_07780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY136_07785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY136_07810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY136_07815	COG2814	Major facilitator Superfamily
FY136_07820	COG0483	inositol monophosphate 1-phosphatase activity
FY136_07825	COG0483	inositol monophosphate 1-phosphatase activity
FY136_07830	COG0037	tRNA processing
FY136_07835	COG2066	Belongs to the glutaminase family
FY136_07840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY136_07845	COG0861	Integral membrane protein TerC family
FY136_07860	COG1280	lysine exporter protein (LysE YggA)
FY136_07875	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY136_07880	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY136_07890	COG0538	isocitrate dehydrogenase activity
FY136_07915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY136_07920	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY136_07925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_07930	COG2313	pseudouridylate synthase activity
FY136_07940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_07945	COG4215	(ABC) transporter
FY136_07955	COG5425	PFAM Usg family protein
FY136_07965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_07970	COG1522	sequence-specific DNA binding
FY136_07975	COG1573	uracil-dna glycosylase
FY136_07985	COG2205	protein histidine kinase activity
FY136_07985	COG2202	Pas domain
FY136_07995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY136_08000	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY136_08015	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY136_08020	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_08025	COG1129	ABC transporter
FY136_08035	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_08040	COG3959	Transketolase, thiamine diphosphate binding domain
FY136_08045	COG3958	Transketolase
FY136_08050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY136_08055	COG2390	Transcriptional regulator
FY136_08065	COG0842	Transport permease protein
FY136_08070	COG1131	(ABC) transporter
FY136_08085	COG0840	transmembrane signaling receptor activity
FY136_08085	COG0840	transmembrane signaling receptor activity
FY136_08095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY136_08100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY136_08125	COG0129	dihydroxy-acid dehydratase activity
FY136_08130	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY136_08135	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY136_08145	COG0203	ribosomal protein L17
FY136_08150	COG0202	RNA polymerase activity
FY136_08155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY136_08160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY136_08165	COG0563	adenylate kinase activity
FY136_08170	COG0201	protein transport
FY136_08175	COG0200	Binds to the 23S rRNA
FY136_08180	COG1841	ribosomal large subunit assembly
FY136_08185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY136_08190	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY136_08195	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY136_08200	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY136_08205	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY136_08210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY136_08215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY136_08220	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY136_08225	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY136_08230	COG0255	Belongs to the universal ribosomal protein uL29 family
FY136_08235	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY136_08240	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY136_08245	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY136_08250	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY136_08255	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY136_08260	COG0089	rRNA binding
FY136_08265	COG0088	Forms part of the polypeptide exit tunnel
FY136_08270	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY136_08275	COG0051	transcription antitermination factor activity, RNA binding
FY136_08280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY136_08285	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY136_08290	COG0049	tRNA binding
FY136_08295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY136_08315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY136_08320	COG0085	RNA polymerase activity
FY136_08325	COG0222	ribosome binding
FY136_08330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY136_08335	COG0081	regulation of translation
FY136_08340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY136_08350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY136_08365	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY136_08370	COG0861	Integral membrane protein TerC family
FY136_08395	COG1132	(ABC) transporter
FY136_08420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY136_08425	COG1607	acyl-coa hydrolase
FY136_08450	COG2910	NAD(P)H-binding
FY136_08455	COG1733	regulation of RNA biosynthetic process
FY136_08470	COG0556	nucleotide-excision repair
FY136_08480	COG2382	esterase
FY136_08500	COG0484	heat shock protein binding
FY136_08530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY136_08535	COG1840	ABC-type Fe3 transport system, periplasmic component
FY136_08540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY136_08560	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY136_08570	COG1733	regulation of RNA biosynthetic process
FY136_08580	COG2207	Transcriptional regulator
FY136_08585	COG1064	alcohol dehydrogenase
FY136_08590	COG1252	NADH dehydrogenase
FY136_08595	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY136_08605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY136_08610	COG0702	epimerase
FY136_08650	COG0656	L-ascorbic acid biosynthetic process
FY136_08665	COG0440	acetolactate synthase activity
FY136_08670	COG0028	Belongs to the TPP enzyme family
FY136_08680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY136_08685	COG3830	Belongs to the UPF0237 family
FY136_08685	COG0560	Phosphoserine phosphatase
FY136_08705	COG0330	HflC and HflK could
FY136_08710	COG0330	HflC and HflK could
FY136_08720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY136_08760	COG0277	FAD linked oxidase domain protein
FY136_08765	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY136_08805	COG1335	isochorismatase
FY136_08830	COG2264	protein methyltransferase activity
FY136_08835	COG1999	signal sequence binding
FY136_08845	COG0835	chemotaxis
FY136_08855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY136_08860	COG0583	DNA-binding transcription factor activity
FY136_08865	COG0697	spore germination
FY136_08870	COG1247	-acetyltransferase
FY136_08880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY136_08885	COG0497	DNA recombination
FY136_08890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY136_08900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY136_08905	COG0849	cell division
FY136_08910	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY136_08915	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY136_08920	COG0477	Major facilitator Superfamily
FY136_08925	COG5001	Diguanylate cyclase
FY136_08925	COG3300	MHYT domain
FY136_08930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY136_08935	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY136_08940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY136_08950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY136_08955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY136_08965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY136_08980	COG0275	rRNA processing
FY136_08985	COG2001	Belongs to the MraZ family
FY136_09020	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY136_09025	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FY136_09050	COG4106	trans-aconitate 2-methyltransferase activity
FY136_09070	COG2226	methyltransferase
FY136_09080	COG2267	carboxylic ester hydrolase activity
FY136_09085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY136_09115	COG0251	oxidation-reduction process
FY136_09130	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_09135	COG2814	Major facilitator Superfamily
FY136_09155	COG1012	belongs to the aldehyde dehydrogenase family
FY136_09160	COG0174	glutamine synthetase
FY136_09165	COG0531	amino acid
FY136_09175	COG1737	Transcriptional regulator
FY136_09195	COG3842	ATPase activity
FY136_09255	COG2968	Membrane
FY136_09265	COG0432	Pfam Uncharacterised protein family UPF0047
FY136_09280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY136_09285	COG0358	DNA primase activity
FY136_09295	COG0505	Belongs to the CarA family
FY136_09300	COG0534	Mate efflux family protein
FY136_09315	COG2321	neutral zinc metallopeptidase
FY136_09330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY136_09345	COG3706	GGDEF domain
FY136_09350	COG1573	uracil-dna glycosylase
FY136_09360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY136_09370	COG1522	sequence-specific DNA binding
FY136_09375	COG0492	ferredoxin-NADP+ reductase activity
FY136_09380	COG0583	DNA-binding transcription factor activity
FY136_09390	COG1902	pentaerythritol trinitrate reductase activity
FY136_09415	COG0387	Pfam Sodium calcium exchanger
FY136_09420	COG0436	Aminotransferase
FY136_09425	COG2199	diguanylate cyclase activity
FY136_09425	COG2200	EAL domain
FY136_09440	COG1278	Cold shock
FY136_09445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY136_09455	COG1846	Transcriptional regulator
FY136_09460	COG0745	RESPONSE REGULATOR receiver
FY136_09465	COG2205	protein histidine kinase activity
FY136_09470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY136_09490	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY136_09500	COG1496	oxidoreductase activity
FY136_09515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY136_09540	COG0840	transmembrane signaling receptor activity
FY136_09545	COG1012	belongs to the aldehyde dehydrogenase family
FY136_09555	COG5001	Diguanylate cyclase
FY136_09555	COG3300	MHYT domain
FY136_09560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY136_09565	COG5001	Diguanylate cyclase
FY136_09575	COG0193	aminoacyl-tRNA hydrolase activity
FY136_09585	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY136_09605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY136_09610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY136_09615	COG2857	Cytochrome c1
FY136_09615	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY136_09635	COG0840	transmembrane signaling receptor activity
FY136_09640	COG1132	(ABC) transporter
FY136_09650	COG1132	(ABC) transporter
FY136_09655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY136_09665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY136_09680	COG0408	coproporphyrinogen oxidase activity
FY136_09695	COG0617	tRNA 3'-terminal CCA addition
FY136_09700	COG0494	nUDIX hydrolase
FY136_09710	COG0714	Associated with various cellular activities
FY136_09730	COG0454	-acetyltransferase
FY136_09745	COG0477	Major facilitator Superfamily
FY136_09755	COG0435	Glutathione S-transferase
FY136_09760	COG0494	nUDIX hydrolase
FY136_09770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY136_09775	COG3135	benzoate transporter
FY136_09800	COG0740	serine-type endopeptidase activity
FY136_09815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY136_09820	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY136_09845	COG4175	Glycine betaine
FY136_09865	COG1435	thymidine kinase activity
FY136_09885	COG2862	Uncharacterized protein family, UPF0114
FY136_09890	COG1629	transport
FY136_09890	COG4771	TonB-dependent receptor
FY136_09900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY136_09900	COG0512	Glutamine amidotransferase of anthranilate synthase
FY136_09915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY136_09925	COG0366	Alpha amylase catalytic
FY136_09930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_09950	COG1160	GTP binding
FY136_09970	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY136_09980	COG0024	Methionine aminopeptidase
FY136_09990	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_10000	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY136_10010	COG0583	DNA-binding transcription factor activity
FY136_10025	COG0402	S-adenosylhomocysteine deaminase activity
FY136_10035	COG1304	FMN binding
FY136_10045	COG1309	transcriptional regulator
FY136_10050	COG1686	Belongs to the peptidase S11 family
FY136_10060	COG2351	hydroxyisourate hydrolase activity
FY136_10065	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY136_10090	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY136_10095	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY136_10095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_10100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_10100	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY136_10105	COG5002	protein histidine kinase activity
FY136_10105	COG2205	protein histidine kinase activity
FY136_10105	COG0784	Response regulator, receiver
FY136_10110	COG0513	Belongs to the DEAD box helicase family
FY136_10120	COG2259	Doxx family
FY136_10125	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_10135	COG2308	Evidence 4 Homologs of previously reported genes of
FY136_10145	COG1305	Transglutaminase-like
FY136_10175	COG4214	carbohydrate transport
FY136_10185	COG4213	ABC transporter substrate-binding protein
FY136_10220	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY136_10230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY136_10245	COG1278	Cold shock
FY136_10255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY136_10300	COG3706	GGDEF domain
FY136_10330	COG4974	Belongs to the 'phage' integrase family
FY136_10335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_10355	COG1396	sequence-specific DNA binding
FY136_10360	COG1247	-acetyltransferase
FY136_10365	COG3238	Protein conserved in bacteria
FY136_10370	COG0840	transmembrane signaling receptor activity
FY136_10375	COG2814	Major facilitator Superfamily
FY136_10385	COG0646	methionine synthase
FY136_10385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY136_10430	COG1215	transferase activity, transferring glycosyl groups
FY136_10460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY136_10465	COG2346	COG2346, Truncated hemoglobins
FY136_10485	COG1309	transcriptional regulator
FY136_10500	COG0494	nUDIX hydrolase
FY136_10510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_10515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_10545	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY136_10550	COG0830	nickel cation binding
FY136_10555	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY136_10570	COG0804	urea catabolic process
FY136_10575	COG1442	glycosyl transferase family 8
FY136_10580	COG3755	Protein conserved in bacteria
FY136_10590	COG0832	Belongs to the urease beta subunit family
FY136_10595	COG3813	Protein conserved in bacteria
FY136_10600	COG0831	urea catabolic process
FY136_10605	COG0829	nickel cation binding
FY136_10625	COG0411	ABC transporter
FY136_10635	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY136_10650	COG0174	glutamine synthetase
FY136_10655	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_10660	COG2198	Histidine kinase
FY136_10660	COG0784	Response regulator, receiver
FY136_10660	COG5002	protein histidine kinase activity
FY136_10710	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY136_10785	COG0564	pseudouridine synthase activity
FY136_10795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY136_10805	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY136_10830	COG0346	lactoylglutathione lyase activity
FY136_10840	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY136_10850	COG2832	Protein of unknown function (DUF454)
FY136_10855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY136_10860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_10865	COG4558	Periplasmic binding protein
FY136_10875	COG3721	Heme iron utilization protein
FY136_10890	COG3657	addiction module killer protein
FY136_10900	COG2205	protein histidine kinase activity
FY136_10940	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_10945	COG4605	iron ion homeostasis
FY136_10950	COG4604	ABC transporter, ATP-binding protein
FY136_10955	COG0783	Belongs to the Dps family
FY136_10970	COG0656	L-ascorbic acid biosynthetic process
FY136_10975	COG2814	Major facilitator Superfamily
FY136_10985	COG0583	DNA-binding transcription factor activity
FY136_10990	COG0657	acetylesterase activity
FY136_10995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_11015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY136_11020	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY136_11025	COG0288	reversible hydration of carbon dioxide
FY136_11035	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY136_11055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY136_11060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY136_11065	COG0778	Nitroreductase
FY136_11070	COG2267	carboxylic ester hydrolase activity
FY136_11075	COG0251	oxidation-reduction process
FY136_11080	COG1335	isochorismatase
FY136_11085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_11095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_11110	COG1175	transmembrane transport
FY136_11115	COG0395	ABC-type sugar transport system, permease component
FY136_11120	COG3842	ATPase activity
FY136_11125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_11135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY136_11150	COG4608	Belongs to the ABC transporter superfamily
FY136_11155	COG0444	Belongs to the ABC transporter superfamily
FY136_11160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_11165	COG0601	transmembrane transport
FY136_11220	COG2159	amidohydrolase
FY136_11225	COG1960	acyl-CoA dehydrogenase activity
FY136_11255	COG0745	RESPONSE REGULATOR receiver
FY136_11265	COG1902	pentaerythritol trinitrate reductase activity
FY136_11265	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY136_11280	COG4232	protein-disulfide reductase activity
FY136_11285	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FY136_11285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY136_11295	COG1388	LysM domain
FY136_11295	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_11305	COG3708	Transcriptional regulator
FY136_11305	COG2207	Transcriptional regulator
FY136_11315	COG0583	DNA-binding transcription factor activity
FY136_11325	COG1335	isochorismatase
FY136_11335	COG0583	DNA-binding transcription factor activity
FY136_11340	COG0583	DNA-binding transcription factor activity
FY136_11345	COG1335	isochorismatase
FY136_11365	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY136_11400	COG1088	dTDP-glucose 4,6-dehydratase activity
FY136_11405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY136_11415	COG1609	Transcriptional regulator
FY136_11430	COG1175	transmembrane transport
FY136_11435	COG0395	ABC-type sugar transport system, permease component
FY136_11440	COG3842	ATPase activity
FY136_11445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY136_11480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY136_11490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_11495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY136_11505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY136_11530	COG0583	DNA-binding transcription factor activity
FY136_11535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_11540	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY136_11545	COG4149	molybdate abc transporter
FY136_11550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY136_11565	COG2022	thiamine diphosphate biosynthetic process
FY136_11580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY136_11585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY136_11595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY136_11620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY136_11620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY136_11645	COG0438	transferase activity, transferring glycosyl groups
FY136_11665	COG4166	transmembrane transport
FY136_11675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_11685	COG0438	transferase activity, transferring glycosyl groups
FY136_11690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY136_11695	COG3142	Participates in the control of copper homeostasis
FY136_11700	COG2814	Major facilitator Superfamily
FY136_11715	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_11720	COG1737	Transcriptional regulator
FY136_11730	COG3842	ATPase activity
FY136_11740	COG0395	ABC-type sugar transport system, permease component
FY136_11745	COG1175	transmembrane transport
FY136_11760	COG2188	Transcriptional regulator
FY136_11765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY136_11770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY136_11775	COG1940	carbohydrate kinase activity
FY136_11785	COG0671	phosphoesterase, PA-phosphatase related
FY136_11790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY136_11795	COG0156	8-amino-7-oxononanoate synthase activity
FY136_11805	COG0729	surface antigen
FY136_11815	COG0835	chemotaxis
FY136_11825	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY136_11830	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY136_11835	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY136_11840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY136_11845	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY136_11850	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY136_11865	COG4974	Belongs to the 'phage' integrase family
FY136_11890	COG1280	lysine exporter protein (LysE YggA)
FY136_11900	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY136_11905	COG0567	Dehydrogenase, E1 component
FY136_11910	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY136_11915	COG0045	succinate-CoA ligase (ADP-forming) activity
FY136_11920	COG0039	L-malate dehydrogenase activity
FY136_11925	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY136_11960	COG2264	protein methyltransferase activity
FY136_11975	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY136_11980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY136_11985	COG0181	hydroxymethylbilane synthase activity
FY136_12025	COG1872	DUF167
FY136_12030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY136_12040	COG1217	gtp-binding protein TYPA
FY136_12045	COG0339	signal peptide processing
FY136_12055	COG1846	Transcriptional regulator
FY136_12060	COG2814	Major facilitator Superfamily
FY136_12065	COG0137	argininosuccinate synthase activity
FY136_12075	COG1280	lysine exporter protein (LysE YggA)
FY136_12080	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY136_12085	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY136_12095	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY136_12110	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY136_12115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY136_12120	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY136_12130	COG4181	ATPase activity
FY136_12140	COG0670	Belongs to the BI1 family
FY136_12155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY136_12165	COG4133	protoheme IX ABC transporter activity
FY136_12170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY136_12175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY136_12200	COG2917	probably involved in intracellular septation
FY136_12205	COG0552	protein localization to endoplasmic reticulum
FY136_12210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY136_12215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY136_12225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY136_12230	COG0287	Prephenate dehydrogenase
FY136_12230	COG1605	Chorismate mutase
FY136_12235	COG0228	four-way junction DNA binding
FY136_12240	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY136_12245	COG0336	Belongs to the RNA methyltransferase TrmD family
FY136_12255	COG0335	large ribosomal subunit rRNA binding
FY136_12265	COG0765	amino acid transport
FY136_12275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY136_12295	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY136_12315	COG0488	(ABC) transporter
FY136_12325	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY136_12335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY136_12340	COG0142	geranyltranstransferase activity
FY136_12345	COG2885	chlorophyll binding
FY136_12350	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY136_12355	COG2223	nitrite transmembrane transporter activity
FY136_12360	COG1349	DNA-binding transcription factor activity
FY136_12365	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY136_12370	COG2197	response regulator
FY136_12375	COG1132	(ABC) transporter
FY136_12385	COG3459	Glycosyltransferase 36 associated
FY136_12390	COG1473	amidohydrolase
FY136_12395	COG0579	oxidoreductase
FY136_12405	COG0129	dihydroxy-acid dehydratase activity
FY136_12410	COG2084	Dehydrogenase
FY136_12415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY136_12420	COG0277	FAD linked oxidase domain protein
FY136_12425	COG2186	Transcriptional regulator
FY136_12435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY136_12440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_12445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY136_12450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY136_12465	COG0495	leucyl-tRNA aminoacylation
FY136_12480	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY136_12485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY136_12495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY136_12500	COG1946	Acyl-CoA thioesterase
FY136_12505	COG0347	Belongs to the P(II) protein family
FY136_12510	COG0004	ammonium transporteR
FY136_12515	COG1674	ftsk spoiiie
FY136_12520	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY136_12535	COG0745	RESPONSE REGULATOR receiver
FY136_12545	COG1329	Transcriptional regulator
FY136_12550	COG2902	Dehydrogenase
FY136_12555	COG2270	Major facilitator Superfamily
FY136_12565	COG0183	Belongs to the thiolase family
FY136_12570	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_12585	COG0494	nUDIX hydrolase
FY136_12595	COG0793	Belongs to the peptidase S41A family
FY136_12605	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY136_12610	COG0799	negative regulation of ribosome biogenesis
FY136_12615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY136_12620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY136_12625	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY136_12630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY136_12645	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY136_12650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY136_12675	COG0066	3-isopropylmalate dehydratase activity
FY136_12680	COG0473	3-isopropylmalate dehydrogenase activity
FY136_12685	COG1858	cytochrome C peroxidase
FY136_12690	COG1797	cobyrinic acid a,c-diamide synthase activity
FY136_12695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY136_12695	COG1648	precorrin-2 dehydrogenase activity
FY136_12700	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY136_12765	COG1492	cobalamin metabolic process
FY136_12780	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_12785	COG3254	rhamnose metabolic process
FY136_12790	COG0246	Mannitol dehydrogenase
FY136_12795	COG1063	alcohol dehydrogenase
FY136_12815	COG4214	carbohydrate transport
FY136_12820	COG1129	ABC transporter
FY136_12825	COG2186	Transcriptional regulator
FY136_12830	COG2721	sulfolactate sulfo-lyase activity
FY136_12835	COG0138	bifunctional purine biosynthesis protein purh
FY136_12845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY136_12845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY136_12850	COG0501	Belongs to the peptidase M48B family
FY136_12870	COG0357	Ribosomal RNA small subunit methyltransferase G
FY136_12875	COG0445	tRNA wobble uridine modification
FY136_12880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY136_12885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY136_12890	COG1981	membrane
FY136_12895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY136_12900	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY136_12905	COG0424	maF-like protein
FY136_12910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY136_12915	COG0237	dephospho-CoA kinase activity
FY136_12925	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY136_12930	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY136_12940	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY136_12965	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY136_12980	COG0135	phosphoribosylanthranilate isomerase activity
FY136_12985	COG0133	tryptophan synthase activity
FY136_12990	COG0159	tryptophan synthase activity
FY136_12995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY136_13010	COG1074	ATP-dependent DNA helicase activity
FY136_13020	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY136_13030	COG2205	protein histidine kinase activity
FY136_13035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY136_13040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY136_13045	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY136_13045	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY136_13050	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY136_13055	COG0642	Histidine kinase
FY136_13060	COG0745	RESPONSE REGULATOR receiver
FY136_13065	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY136_13075	COG1652	LysM domain
FY136_13080	COG1072	(Pantothenic acid kinase))
FY136_13085	COG0140	phosphoribosyl-ATP diphosphatase activity
FY136_13090	COG0107	imidazoleglycerol-phosphate synthase activity
FY136_13095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY136_13100	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY136_13110	COG0131	Imidazoleglycerol-phosphate dehydratase
FY136_13115	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY136_13120	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY136_13130	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY136_13145	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY136_13155	COG1643	Atp-dependent helicase
FY136_13195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FY136_13200	COG3668	Plasmid stabilization system
FY136_13215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY136_13220	COG1733	regulation of RNA biosynthetic process
FY136_13285	COG1335	isochorismatase
FY136_13290	COG1902	pentaerythritol trinitrate reductase activity
FY136_13295	COG1741	Belongs to the pirin family
FY136_13315	COG1196	nuclear chromosome segregation
FY136_13320	COG0514	ATP-dependent DNA helicase (RecQ)
FY136_13345	COG1072	(Pantothenic acid kinase))
FY136_13355	COG1780	Probably involved in ribonucleotide reductase function
FY136_13375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY136_13405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_13415	COG2813	Specifically methylates the guanine in position
FY136_13420	COG1185	polyribonucleotide nucleotidyltransferase activity
FY136_13425	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY136_13430	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY136_13435	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY136_13440	COG3064	Membrane
FY136_13440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY136_13455	COG0779	Required for maturation of 30S ribosomal subunits
FY136_13460	COG2814	Major facilitator Superfamily
FY136_13465	COG2951	lytic endotransglycosylase activity
FY136_13470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY136_13480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY136_13485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY136_13500	COG2816	NAD+ diphosphatase activity
FY136_13505	COG0077	Prephenate dehydratase
FY136_13505	COG1605	Chorismate mutase
FY136_13510	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY136_13515	COG3474	cytochrome
FY136_13525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY136_13530	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY136_13535	COG1278	Cold shock
FY136_13540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY136_13550	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY136_13550	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY136_13560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY136_13590	COG2900	Belongs to the SlyX family
FY136_13600	COG0484	heat shock protein binding
FY136_13605	COG0443	Heat shock 70 kDa protein
FY136_13630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY136_13635	COG1744	ABC transporter substrate-binding protein PnrA-like
FY136_13640	COG3845	ABC transporter
FY136_13645	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY136_13650	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY136_13655	COG0295	cytidine deaminase activity
FY136_13660	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY136_13665	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY136_13670	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY136_13680	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY136_13685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY136_13690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY136_13700	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY136_13705	COG1845	cytochrome c oxidase, subunit III
FY136_13710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY136_13720	COG0477	Major facilitator Superfamily
FY136_13725	COG0069	glutamate synthase activity
FY136_13725	COG0067	glutamate synthase
FY136_13725	COG0070	glutamate synthase
FY136_13730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY136_13745	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY136_13755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY136_13785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_13805	COG0848	biopolymer transport protein
FY136_13815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY136_13830	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY136_13835	COG3454	Phosphonate metabolism
FY136_13840	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY136_13845	COG3639	organic phosphonate transmembrane transporter activity
FY136_13850	COG3639	organic phosphonate transmembrane transporter activity
FY136_13855	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY136_13860	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY136_13870	COG4778	phosphonate C-P lyase system protein PhnL
FY136_13875	COG4107	phosphonate C-P lyase system protein PhnK
FY136_13880	COG3627	carbon phosphorus lyase activity
FY136_13885	COG3626	phosphonate metabolism
FY136_13890	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY136_13895	COG3624	Phosphonate C-P lyase system protein PhnG
FY136_13900	COG2188	Transcriptional regulator
FY136_13905	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY136_13910	COG0837	glucose binding
FY136_13915	COG1803	Methylglyoxal synthase
FY136_13920	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY136_13925	COG4166	transmembrane transport
FY136_13930	COG4174	ABC transporter (Permease)
FY136_13935	COG4239	(ABC) transporter, permease
FY136_13940	COG4172	Belongs to the ABC transporter superfamily
FY136_13945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_13950	COG0174	glutamine synthetase
FY136_13955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_13960	COG3265	gluconokinase activity
FY136_13965	COG1174	glycine betaine transport
FY136_13970	COG1125	glycine betaine transport
FY136_13975	COG1174	glycine betaine transport
FY136_13980	COG1732	Glycine betaine
FY136_13990	COG1959	2 iron, 2 sulfur cluster binding
FY136_13995	COG1840	ABC-type Fe3 transport system, periplasmic component
FY136_14000	COG0501	Belongs to the peptidase M48B family
FY136_14005	COG4269	membrane
FY136_14020	COG0697	spore germination
FY136_14040	COG0791	NLP P60 protein
FY136_14050	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY136_14090	COG4964	Belongs to the GSP D family
FY136_14135	COG3422	double-strand break repair
FY136_14140	COG3757	hydrolase, family 25
FY136_14145	COG0697	spore germination
FY136_14150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY136_14180	COG0481	GTPase activity
FY136_14185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY136_14200	COG1396	sequence-specific DNA binding
FY136_14215	COG1917	Cupin 2, conserved barrel domain protein
FY136_14215	COG2169	Transcriptional regulator
FY136_14220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY136_14245	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY136_14250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY136_14255	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY136_14265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY136_14270	COG0072	phenylalanine-tRNA ligase activity
FY136_14270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY136_14275	COG0667	Aldo Keto reductase
FY136_14295	COG4977	sequence-specific DNA binding
FY136_14320	COG1570	exodeoxyribonuclease VII activity
FY136_14325	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_14335	COG1846	Transcriptional regulator
FY136_14340	COG0697	spore germination
FY136_14345	COG2309	aminopeptidase activity
FY136_14355	COG1393	Belongs to the ArsC family
FY136_14380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY136_14380	COG0519	Catalyzes the synthesis of GMP from XMP
FY136_14395	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY136_14425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY136_14435	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY136_14445	COG1968	undecaprenyl-diphosphatase activity
FY136_14460	COG0284	orotidine-5'-phosphate decarboxylase activity
FY136_14470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY136_14480	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY136_14485	COG0792	nuclease activity
FY136_14500	COG1175	transmembrane transport
FY136_14505	COG0395	ABC-type sugar transport system, permease component
FY136_14510	COG3842	ATPase activity
FY136_14520	COG0189	ligase activity
FY136_14525	COG0606	chelatase, subunit chli
FY136_14530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY136_14535	COG1280	lysine exporter protein (LysE YggA)
FY136_14540	COG0756	dUTP diphosphatase activity
FY136_14545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY136_14550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY136_14570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY136_14575	COG2226	methyltransferase
FY136_14580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY136_14585	COG1024	Enoyl-CoA hydratase
FY136_14590	COG0268	Binds directly to 16S ribosomal RNA
FY136_14640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY136_14650	COG3209	COG3209 Rhs family protein
FY136_14665	COG2963	transposase activity
FY136_14680	COG1012	belongs to the aldehyde dehydrogenase family
FY136_14700	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_14705	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_14710	COG1129	ABC transporter
FY136_14715	COG1879	ABC-type sugar transport system periplasmic component
FY136_14720	COG1349	DNA-binding transcription factor activity
FY136_14740	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FY136_14790	COG2963	transposase activity
FY136_14795	COG3436	PFAM IS66 Orf2 family protein
FY136_14800	COG4372	Transposase
FY136_14850	COG1368	sulfuric ester hydrolase activity
FY136_14855	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_14930	COG1082	Xylose isomerase domain protein TIM barrel
FY136_14950	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_14955	COG1129	ABC transporter
FY136_14975	COG3284	Transcriptional regulator
FY136_14980	COG1063	alcohol dehydrogenase
FY136_14990	COG0488	(ABC) transporter
FY136_14995	COG5265	(ABC) transporter
FY136_15000	COG3181	Tripartite tricarboxylate transporter family receptor
FY136_15015	COG3842	ATPase activity
FY136_15025	COG1840	ABC-type Fe3 transport system, periplasmic component
FY136_15030	COG1840	ABC-type Fe3 transport system, periplasmic component
FY136_15055	COG0405	Gamma-glutamyltransferase
FY136_15060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_15065	COG0601	transmembrane transport
FY136_15070	COG0747	negative chemotaxis
FY136_15075	COG2186	Transcriptional regulator
FY136_15085	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_15090	COG4172	Belongs to the ABC transporter superfamily
FY136_15095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_15100	COG0601	transmembrane transport
FY136_15105	COG0747	negative chemotaxis
FY136_15110	COG2186	Transcriptional regulator
FY136_15120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_15125	COG2223	nitrite transmembrane transporter activity
FY136_15135	COG3383	formate dehydrogenase (NAD+) activity
FY136_15160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY136_15165	COG1802	Transcriptional regulator
FY136_15170	COG4608	Belongs to the ABC transporter superfamily
FY136_15175	COG0444	Belongs to the ABC transporter superfamily
FY136_15180	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY136_15190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_15195	COG0601	transmembrane transport
FY136_15205	COG0402	S-adenosylhomocysteine deaminase activity
FY136_15220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY136_15230	COG0765	amino acid transport
FY136_15235	COG0765	amino acid transport
FY136_15240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_15250	COG1609	Transcriptional regulator
FY136_15255	COG3938	Belongs to the proline racemase family
FY136_15265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_15275	COG0765	amino acid transport
FY136_15290	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY136_15295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_15305	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY136_15310	COG0784	Response regulator, receiver
FY136_15325	COG1486	melibiose metabolic process
FY136_15330	COG4172	Belongs to the ABC transporter superfamily
FY136_15335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_15340	COG0601	transmembrane transport
FY136_15345	COG0747	negative chemotaxis
FY136_15350	COG1486	melibiose metabolic process
FY136_15375	COG1940	carbohydrate kinase activity
FY136_15380	COG2182	Extracellular solute-binding protein
FY136_15385	COG1175	transmembrane transport
FY136_15390	COG0395	ABC-type sugar transport system, permease component
FY136_15395	COG0165	Argininosuccinate lyase
FY136_15400	COG3842	ATPase activity
FY136_15405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_15410	COG3119	arylsulfatase activity
FY136_15425	COG1012	belongs to the aldehyde dehydrogenase family
FY136_15460	COG3657	addiction module killer protein
FY136_15465	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY136_15470	COG1120	ATPase activity
FY136_15475	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_15480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_15490	COG4774	siderophore transport
FY136_15500	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY136_15545	COG5002	protein histidine kinase activity
FY136_15550	COG0745	RESPONSE REGULATOR receiver
FY136_15570	COG1392	Phosphate transport regulator
FY136_15575	COG0306	phosphate transporter
FY136_15580	COG5001	Diguanylate cyclase
FY136_15580	COG3300	MHYT domain
FY136_15595	COG1312	Catalyzes the dehydration of D-mannonate
FY136_15600	COG2186	Transcriptional regulator
FY136_15605	COG0601	transmembrane transport
FY136_15610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_15615	COG0444	Belongs to the ABC transporter superfamily
FY136_15635	COG0210	DNA helicase
FY136_15640	COG4774	siderophore transport
FY136_15645	COG1120	ATPase activity
FY136_15650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_15655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_15670	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY136_15675	COG1088	dTDP-glucose 4,6-dehydratase activity
FY136_15680	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY136_15685	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY136_15695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY136_15700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY136_15705	COG1132	(ABC) transporter
FY136_15720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_15730	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_15740	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY136_15750	COG0583	DNA-binding transcription factor activity
FY136_15755	COG0667	Aldo Keto reductase
FY136_15760	COG0385	Bile acid
FY136_15770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY136_15785	COG0300	oxidoreductase activity
FY136_15790	COG0483	inositol monophosphate 1-phosphatase activity
FY136_15795	COG0584	glycerophosphoryl diester phosphodiesterase
FY136_15805	COG4149	molybdate abc transporter
FY136_15810	COG3842	ATPase activity
FY136_15820	COG1940	carbohydrate kinase activity
FY136_15830	COG3712	iron ion homeostasis
FY136_15835	COG4774	siderophore transport
FY136_15840	COG2814	Major facilitator Superfamily
FY136_15860	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY136_15875	COG1175	transmembrane transport
FY136_15880	COG0395	ABC-type sugar transport system, permease component
FY136_15885	COG1609	Transcriptional regulator
FY136_15895	COG0673	inositol 2-dehydrogenase activity
FY136_15900	COG1082	Xylose isomerase domain protein TIM barrel
FY136_15915	COG1609	Transcriptional regulator
FY136_15920	COG0183	Belongs to the thiolase family
FY136_15925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY136_15935	COG1414	Transcriptional regulator
FY136_15950	COG0583	DNA-binding transcription factor activity
FY136_15960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY136_15965	COG3485	protocatechuate 3,4-dioxygenase
FY136_15970	COG3485	protocatechuate 3,4-dioxygenase
FY136_15980	COG0765	amino acid transport
FY136_15985	COG0765	amino acid transport
FY136_15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_15995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_16000	COG1126	abc transporter atp-binding protein
FY136_16005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY136_16010	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY136_16035	COG4172	Belongs to the ABC transporter superfamily
FY136_16040	COG0747	negative chemotaxis
FY136_16050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_16060	COG2207	Transcriptional regulator
FY136_16070	COG0683	leucine binding
FY136_16080	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY136_16085	COG0411	ABC transporter
FY136_16100	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_16105	COG3962	Belongs to the TPP enzyme family
FY136_16115	COG3718	enzyme involved in inositol metabolism
FY136_16125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY136_16130	COG1609	Transcriptional regulator
FY136_16135	COG1846	Transcriptional regulator
FY136_16145	COG0523	cobalamin synthesis protein
FY136_16180	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY136_16200	COG0800	Aldolase
FY136_16205	COG2954	triphosphatase activity
FY136_16215	COG1054	Belongs to the UPF0176 family
FY136_16220	COG3300	MHYT domain
FY136_16220	COG5001	Diguanylate cyclase
FY136_16240	COG2011	ABC-type metal ion transport system permease component
FY136_16245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY136_16250	COG0778	Nitroreductase
FY136_16285	COG0583	DNA-binding transcription factor activity
FY136_16290	COG1879	ABC-type sugar transport system periplasmic component
FY136_16295	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_16300	COG1129	ABC transporter
FY136_16310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY136_16315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_16320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FY136_16325	COG1309	transcriptional regulator
FY136_16335	COG3257	ureidoglycine aminohydrolase activity
FY136_16345	COG5001	Diguanylate cyclase
FY136_16350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY136_16360	COG0747	negative chemotaxis
FY136_16365	COG0601	transmembrane transport
FY136_16370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_16375	COG0444	Belongs to the ABC transporter superfamily
FY136_16380	COG4608	Belongs to the ABC transporter superfamily
FY136_16385	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY136_16400	COG0346	lactoylglutathione lyase activity
FY136_16410	COG0129	dihydroxy-acid dehydratase activity
FY136_16415	COG1879	ABC-type sugar transport system periplasmic component
FY136_16420	COG1129	ABC transporter
FY136_16425	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_16430	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_16435	COG2186	Transcriptional regulator
FY136_16450	COG0523	cobalamin synthesis protein
FY136_16455	COG1653	transport
FY136_16460	COG1175	transmembrane transport
FY136_16465	COG0395	ABC-type sugar transport system, permease component
FY136_16470	COG3842	ATPase activity
FY136_16480	COG3047	cAMP biosynthetic process
FY136_16485	COG2115	Belongs to the xylose isomerase family
FY136_16490	COG1070	Carbohydrate kinase
FY136_16495	COG1609	Transcriptional regulator
FY136_16510	COG1309	transcriptional regulator
FY136_16515	COG1253	flavin adenine dinucleotide binding
FY136_16520	COG2827	Endonuclease containing a URI domain
FY136_16525	COG3273	potassium ion transport
FY136_16525	COG0471	metal ion transport
FY136_16530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY136_16535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY136_16540	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY136_16550	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY136_16555	COG1121	(ABC) transporter
FY136_16560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY136_16565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY136_16575	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_16580	COG1414	Transcriptional regulator
FY136_16585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY136_16595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY136_16620	COG1069	ribulokinase activity
FY136_16645	COG0395	ABC-type sugar transport system, permease component
FY136_16650	COG1175	transmembrane transport
FY136_16660	COG2390	Transcriptional regulator
FY136_16665	COG4172	Belongs to the ABC transporter superfamily
FY136_16670	COG1473	amidohydrolase
FY136_16680	COG0601	transmembrane transport
FY136_16685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_16695	COG0693	protein deglycase activity
FY136_16705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_16715	COG0747	negative chemotaxis
FY136_16720	COG0583	DNA-binding transcription factor activity
FY136_16730	COG0444	Belongs to the ABC transporter superfamily
FY136_16735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_16740	COG0601	transmembrane transport
FY136_16745	COG0747	negative chemotaxis
FY136_16760	COG1473	amidohydrolase
FY136_16765	COG2814	Major facilitator Superfamily
FY136_16770	COG0583	DNA-binding transcription factor activity
FY136_16775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY136_16785	COG3842	ATPase activity
FY136_16805	COG1609	Transcriptional regulator
FY136_16810	COG0583	DNA-binding transcription factor activity
FY136_16815	COG1960	acyl-CoA dehydrogenase activity
FY136_16820	COG4774	siderophore transport
FY136_16820	COG1629	transport
FY136_16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_16835	COG1120	ATPase activity
FY136_16840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_16845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_16855	COG2375	cellular response to nickel ion
FY136_16865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY136_16870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY136_16870	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY136_16880	COG1169	isochorismate synthase
FY136_16885	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY136_16890	COG1535	isochorismatase
FY136_16890	COG3433	isochorismatase activity
FY136_16895	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_16910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_16915	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY136_16920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY136_16925	COG0583	DNA-binding transcription factor activity
FY136_16930	COG3005	denitrification pathway
FY136_16940	COG0243	molybdopterin cofactor binding
FY136_16955	COG4459	periplasmic nitrate reductase
FY136_16965	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FY136_16990	COG0826	peptidase U32
FY136_17000	COG3189	MarR family transcriptional regulator
FY136_17005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY136_17010	COG0163	prenyltransferase activity
FY136_17035	COG3256	nitric oxide reductase
FY136_17040	COG0714	Associated with various cellular activities
FY136_17100	COG0673	inositol 2-dehydrogenase activity
FY136_17110	COG1609	Transcriptional regulator
FY136_17115	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_17120	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_17125	COG1129	ABC transporter
FY136_17130	COG1879	ABC-type sugar transport system periplasmic component
FY136_17150	COG0668	transmembrane transport
FY136_17160	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY136_17165	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY136_17165	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY136_17175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_17205	COG1177	transmembrane transport
FY136_17210	COG3842	ATPase activity
FY136_17225	COG1082	Xylose isomerase domain protein TIM barrel
FY136_17230	COG1609	Transcriptional regulator
FY136_17235	COG0673	inositol 2-dehydrogenase activity
FY136_17250	COG0583	DNA-binding transcription factor activity
FY136_17280	COG1609	Transcriptional regulator
FY136_17285	COG0673	inositol 2-dehydrogenase activity
FY136_17295	COG1653	transport
FY136_17300	COG1175	transmembrane transport
FY136_17305	COG0395	ABC-type sugar transport system, permease component
FY136_17310	COG3842	ATPase activity
FY136_17315	COG0259	pyridoxamine-phosphate oxidase activity
FY136_17325	COG2188	Transcriptional regulator
FY136_17345	COG0586	Pfam SNARE associated Golgi protein
FY136_17350	COG1253	flavin adenine dinucleotide binding
FY136_17360	COG0483	inositol monophosphate 1-phosphatase activity
FY136_17380	COG3842	ATPase activity
FY136_17385	COG1178	ABC-type Fe3 transport system permease component
FY136_17415	COG3300	MHYT domain
FY136_17415	COG5001	Diguanylate cyclase
FY136_17535	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_17545	COG1879	ABC-type sugar transport system periplasmic component
FY136_17555	COG1063	alcohol dehydrogenase
FY136_17570	COG1136	(ABC) transporter
FY136_17585	COG1309	transcriptional regulator
FY136_17600	COG1522	sequence-specific DNA binding
FY136_17610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY136_17615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY136_17620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY136_17625	COG2423	ornithine cyclodeaminase activity
FY136_17630	COG0006	proline dipeptidase activity
FY136_17635	COG3608	succinylglutamate desuccinylase aspartoacylase
FY136_17640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_17645	COG0765	amino acid transport
FY136_17650	COG0765	amino acid transport
FY136_17655	COG1126	abc transporter atp-binding protein
FY136_17660	COG0583	DNA-binding transcription factor activity
FY136_17665	COG4221	oxidoreductase activity
FY136_17705	COG1929	Belongs to the glycerate kinase type-1 family
FY136_17710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY136_17715	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_17725	COG0583	DNA-binding transcription factor activity
FY136_17750	COG2814	Major facilitator Superfamily
FY136_17775	COG2132	Multicopper oxidase
FY136_17780	COG0583	DNA-binding transcription factor activity
FY136_17785	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FY136_17790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_17795	COG4597	amino acid ABC transporter
FY136_17800	COG0765	amino acid transport
FY136_17805	COG1126	abc transporter atp-binding protein
FY136_17845	COG0739	heme binding
FY136_17845	COG0741	lytic transglycosylase activity
FY136_17845	COG1196	nuclear chromosome segregation
FY136_17850	COG0542	response to heat
FY136_17860	COG2890	protein-(glutamine-N5) methyltransferase activity
FY136_17865	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY136_17875	COG0527	aspartate kinase activity
FY136_17890	COG1309	transcriptional regulator
FY136_17900	COG0019	diaminopimelate decarboxylase activity
FY136_17915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY136_17925	COG3920	Histidine kinase
FY136_17935	COG0784	Response regulator, receiver
FY136_17950	COG1522	sequence-specific DNA binding
FY136_17960	COG1116	anion transmembrane transporter activity
FY136_17965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_17970	COG1012	belongs to the aldehyde dehydrogenase family
FY136_17975	COG0583	DNA-binding transcription factor activity
FY136_17980	COG0435	Glutathione S-transferase
FY136_17990	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY136_17995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY136_18000	COG0189	ligase activity
FY136_18015	COG4993	Dehydrogenase
FY136_18035	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_18040	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY136_18085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_18100	COG0246	Mannitol dehydrogenase
FY136_18105	COG4608	Belongs to the ABC transporter superfamily
FY136_18115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_18120	COG0601	transmembrane transport
FY136_18125	COG0747	negative chemotaxis
FY136_18135	COG4221	oxidoreductase activity
FY136_18165	COG0539	negative regulation of cytoplasmic translation
FY136_18170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY136_18200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY136_18205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY136_18235	COG1294	oxidase, subunit
FY136_18245	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY136_18250	COG4988	ABC transporter
FY136_18260	COG1063	alcohol dehydrogenase
FY136_18265	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_18270	COG2084	Dehydrogenase
FY136_18280	COG1522	sequence-specific DNA binding
FY136_18285	COG1794	racemase activity, acting on amino acids and derivatives
FY136_18300	COG0058	SHG alpha-glucan phosphorylase activity
FY136_18305	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY136_18310	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY136_18315	COG0297	glycogen (starch) synthase activity
FY136_18320	COG0033	Phosphoglucomutase
FY136_18335	COG1733	regulation of RNA biosynthetic process
FY136_18350	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY136_18350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY136_18365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_18370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY136_18390	COG1215	transferase activity, transferring glycosyl groups
FY136_18395	COG2327	Polysaccharide pyruvyl transferase
FY136_18400	COG0463	Glycosyl transferase, family 2
FY136_18405	COG2244	polysaccharide biosynthetic process
FY136_18410	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY136_18415	COG2273	Hydrolase Family 16
FY136_18420	COG0438	transferase activity, transferring glycosyl groups
FY136_18425	COG1215	transferase activity, transferring glycosyl groups
FY136_18430	COG1215	transferase activity, transferring glycosyl groups
FY136_18435	COG1215	transferase activity, transferring glycosyl groups
FY136_18440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY136_18445	COG0489	protein tyrosine kinase activity
FY136_18445	COG3206	protein involved in exopolysaccharide biosynthesis
FY136_18450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY136_18460	COG4176	ABC-type proline glycine betaine transport system permease component
FY136_18465	COG0517	IMP dehydrogenase activity
FY136_18465	COG4175	Glycine betaine
FY136_18480	COG0564	pseudouridine synthase activity
FY136_18485	COG0500	methyltransferase
FY136_18495	COG2133	pyrroloquinoline quinone binding
FY136_18505	COG2197	response regulator
FY136_18510	COG4585	Histidine kinase
FY136_18515	COG1879	ABC-type sugar transport system periplasmic component
FY136_18520	COG1129	ABC transporter
FY136_18525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_18535	COG3386	PFAM SMP-30 Gluconolaconase
FY136_18540	COG2137	regulation of response to DNA damage stimulus
FY136_18545	COG3474	cytochrome
FY136_18555	COG1120	ATPase activity
FY136_18570	COG4774	siderophore transport
FY136_18575	COG0583	DNA-binding transcription factor activity
FY136_18585	COG2194	sulfuric ester hydrolase activity
FY136_18600	COG0477	Major facilitator Superfamily
FY136_18620	COG0673	inositol 2-dehydrogenase activity
FY136_18625	COG0697	spore germination
FY136_18635	COG0010	Belongs to the arginase family
FY136_18650	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY136_18655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY136_18660	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY136_18670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY136_18695	COG0745	RESPONSE REGULATOR receiver
FY136_18700	COG2205	protein histidine kinase activity
FY136_18740	COG0477	Major facilitator Superfamily
FY136_18745	COG0583	DNA-binding transcription factor activity
FY136_18760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY136_18775	COG2268	Band 7 protein
FY136_18780	COG1309	transcriptional regulator
FY136_18800	COG0356	it plays a direct role in the translocation of protons across the membrane
FY136_18805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY136_18815	COG2706	6-phosphogluconolactonase activity
FY136_18855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_18865	COG0583	DNA-binding transcription factor activity
FY136_18875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY136_18880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_18885	COG2274	protein secretion by the type I secretion system
FY136_18900	COG1538	Outer membrane efflux protein
FY136_18905	COG2986	histidine ammonia-lyase
FY136_18910	COG4175	Glycine betaine
FY136_18910	COG0517	IMP dehydrogenase activity
FY136_18915	COG4176	ABC-type proline glycine betaine transport system permease component
FY136_18955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_18960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY136_18965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY136_18970	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_18975	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_18985	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_18990	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_18995	COG1063	alcohol dehydrogenase
FY136_19005	COG3842	ATPase activity
FY136_19010	COG0395	ABC-type sugar transport system, permease component
FY136_19035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FY136_19045	COG3938	Belongs to the proline racemase family
FY136_19050	COG4176	ABC-type proline glycine betaine transport system permease component
FY136_19055	COG4176	ABC-type proline glycine betaine transport system permease component
FY136_19060	COG4175	Glycine betaine
FY136_19060	COG3448	diguanylate cyclase activity
FY136_19075	COG1012	belongs to the aldehyde dehydrogenase family
FY136_19080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_19085	COG1802	Transcriptional regulator
FY136_19105	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_19110	COG3842	ATPase activity
FY136_19130	COG2072	flavoprotein involved in K transport
FY136_19140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_19145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_19150	COG1116	anion transmembrane transporter activity
FY136_19160	COG1522	sequence-specific DNA binding
FY136_19165	COG1733	regulation of RNA biosynthetic process
FY136_19190	COG2382	esterase
FY136_19200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_19205	COG0601	transmembrane transport
FY136_19245	COG1609	Transcriptional regulator
FY136_19250	COG1609	Transcriptional regulator
FY136_19255	COG0747	negative chemotaxis
FY136_19265	COG0601	transmembrane transport
FY136_19270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_19280	COG3622	Belongs to the hyi family
FY136_19285	COG2084	Dehydrogenase
FY136_19315	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY136_19315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY136_19335	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_19345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_19350	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY136_19480	COG2801	Transposase and inactivated derivatives
FY136_19485	COG1609	Transcriptional regulator
FY136_19495	COG0673	inositol 2-dehydrogenase activity
FY136_19500	COG0363	glucosamine-6-phosphate deaminase activity
FY136_19505	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY136_19510	COG3842	ATPase activity
FY136_19520	COG1175	transmembrane transport
FY136_19525	COG0395	ABC-type sugar transport system, permease component
FY136_19530	COG1312	Catalyzes the dehydration of D-mannonate
FY136_19535	COG0246	Mannitol dehydrogenase
FY136_19545	COG1126	abc transporter atp-binding protein
FY136_19550	COG0765	amino acid transport
FY136_19565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY136_19575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY136_19590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY136_19600	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_19605	COG1414	Transcriptional regulator
FY136_19650	COG0402	S-adenosylhomocysteine deaminase activity
FY136_19655	COG1228	amidohydrolase
FY136_19660	COG2986	histidine ammonia-lyase
FY136_19670	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY136_19700	COG1192	Involved in chromosome partitioning
FY136_19705	COG1475	DNA binding
FY136_19710	COG1414	Transcriptional regulator
FY136_19720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY136_19725	COG4771	TonB-dependent receptor
FY136_19735	COG0366	Alpha amylase catalytic
FY136_19740	COG4770	biotin carboxylase activity
FY136_19745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY136_19750	COG4336	lyase activity
FY136_19755	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY136_19760	COG1914	H( )-stimulated, divalent metal cation uptake system
FY136_19765	COG1802	Transcriptional regulator
FY136_19770	COG3707	response regulator
FY136_19780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_19785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_19790	COG1116	anion transmembrane transporter activity
FY136_19795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY136_19805	COG0243	molybdopterin cofactor binding
FY136_19810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY136_19810	COG1648	precorrin-2 dehydrogenase activity
FY136_19825	COG3842	ATPase activity
FY136_19840	COG0395	ABC-type sugar transport system, permease component
FY136_19855	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY136_19870	COG0071	Belongs to the small heat shock protein (HSP20) family
FY136_19900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY136_19905	COG1879	ABC-type sugar transport system periplasmic component
FY136_19910	COG1129	ABC transporter
FY136_19915	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_19925	COG0667	Aldo Keto reductase
FY136_19930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY136_19935	COG1830	Aldolase
FY136_19940	COG1070	Carbohydrate kinase
FY136_19955	COG2076	Multidrug Resistance protein
FY136_19965	COG1647	Serine aminopeptidase, S33
FY136_19975	COG2076	Multidrug Resistance protein
FY136_19985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY136_19990	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FY136_20030	COG3842	ATPase activity
FY136_20035	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_20040	COG1177	transmembrane transport
FY136_20055	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY136_20065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY136_20080	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_20090	COG4172	Belongs to the ABC transporter superfamily
FY136_20095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_20100	COG0601	transmembrane transport
FY136_20105	COG4166	transmembrane transport
FY136_20110	COG0395	ABC-type sugar transport system, permease component
FY136_20175	COG1414	Transcriptional regulator
FY136_20185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY136_20190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_20190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY136_20200	COG1032	radical SAM domain protein
FY136_20215	COG0372	Belongs to the citrate synthase family
FY136_20220	COG0372	Belongs to the citrate synthase family
FY136_20280	COG0300	oxidoreductase activity
FY136_20285	COG0436	Aminotransferase
FY136_20295	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY136_20305	COG3842	ATPase activity
FY136_20310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY136_20315	COG1984	allophanate hydrolase subunit 2
FY136_20320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY136_20330	COG0439	Biotin carboxylase
FY136_20335	COG0511	ligase activity, forming carbon-carbon bonds
FY136_20340	COG0697	spore germination
FY136_20345	COG0697	spore germination
FY136_20360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY136_20375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY136_20380	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_20385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY136_20390	COG4221	oxidoreductase activity
FY136_20395	COG0765	amino acid transport
FY136_20400	COG0765	amino acid transport
FY136_20410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_20415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY136_20420	COG1063	alcohol dehydrogenase
FY136_20430	COG0765	amino acid transport
FY136_20435	COG0765	amino acid transport
FY136_20460	COG1846	Transcriptional regulator
FY136_20470	COG1304	FMN binding
FY136_20495	COG3842	ATPase activity
FY136_20505	COG0395	ABC-type sugar transport system, permease component
FY136_20510	COG1175	transmembrane transport
FY136_20525	COG2186	Transcriptional regulator
FY136_20530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY136_20535	COG0488	(ABC) transporter
FY136_20550	COG2307	Protein conserved in bacteria
FY136_20550	COG2308	Evidence 4 Homologs of previously reported genes of
FY136_20590	COG1454	alcohol dehydrogenase
FY136_20595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY136_20605	COG0747	negative chemotaxis
FY136_20610	COG0601	transmembrane transport
FY136_20615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_20625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_20660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY136_20680	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY136_20695	COG2957	Belongs to the agmatine deiminase family
FY136_20700	COG1082	Xylose isomerase domain protein TIM barrel
FY136_20705	COG1082	Xylose isomerase domain protein TIM barrel
FY136_20710	COG0673	inositol 2-dehydrogenase activity
FY136_20715	COG1082	Xylose isomerase domain protein TIM barrel
FY136_20735	COG1609	Transcriptional regulator
FY136_20745	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY136_20745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY136_20750	COG4311	Sarcosine oxidase, delta subunit
FY136_20755	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_20760	COG4977	sequence-specific DNA binding
FY136_20770	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY136_20775	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY136_20780	COG0069	glutamate synthase activity
FY136_20785	COG0174	glutamine synthetase
FY136_20805	COG0765	amino acid transport
FY136_20810	COG1126	abc transporter atp-binding protein
FY136_20825	COG2267	carboxylic ester hydrolase activity
FY136_20835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_20840	COG1012	belongs to the aldehyde dehydrogenase family
FY136_20860	COG1177	transmembrane transport
FY136_20865	COG3842	ATPase activity
FY136_20875	COG1309	transcriptional regulator
FY136_20890	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY136_20895	COG2186	Transcriptional regulator
FY136_20900	COG1027	Aspartate ammonia-lyase
FY136_20910	COG0252	asparaginase activity
FY136_20920	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY136_20925	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY136_20930	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY136_20935	COG2205	protein histidine kinase activity
FY136_20950	COG0070	glutamate synthase
FY136_20950	COG0067	glutamate synthase
FY136_20950	COG0069	glutamate synthase activity
FY136_20965	COG2205	protein histidine kinase activity
FY136_20980	COG2951	lytic endotransglycosylase activity
FY136_20985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY136_21010	COG0330	HflC and HflK could
FY136_21015	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY136_21020	COG0737	Belongs to the 5'-nucleotidase family
FY136_21030	COG5310	Homospermidine synthase
FY136_21040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY136_21045	COG1164	Oligoendopeptidase f
FY136_21050	COG2204	response regulator
FY136_21055	COG3108	Peptidase M15
FY136_21060	COG0469	pyruvate kinase activity
FY136_21080	COG3750	Belongs to the UPF0335 family
FY136_21085	COG0457	Tetratricopeptide repeat
FY136_21090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY136_21095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY136_21100	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY136_21130	COG0483	inositol monophosphate 1-phosphatase activity
FY136_21155	COG1132	(ABC) transporter
FY136_21160	COG0254	rRNA binding
FY136_21180	COG3588	fructose-bisphosphate aldolase
FY136_21185	COG0126	phosphoglycerate kinase activity
FY136_21225	COG1253	flavin adenine dinucleotide binding
FY136_21235	COG1692	metallophosphoesterase
FY136_21250	COG0217	transcriptional regulatory protein
FY136_21255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_21260	COG0840	transmembrane signaling receptor activity
FY136_21265	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY136_21270	COG0632	four-way junction helicase activity
FY136_21275	COG2255	four-way junction helicase activity
FY136_21290	COG0494	nUDIX hydrolase
FY136_21300	COG0824	Thioesterase
FY136_21320	COG0823	Involved in the tonB-independent uptake of proteins
FY136_21325	COG2885	chlorophyll binding
FY136_21335	COG0037	tRNA processing
FY136_21340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY136_21345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY136_21360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY136_21375	COG0482	sulfurtransferase activity
FY136_21395	COG3118	belongs to the thioredoxin family
FY136_21405	COG2835	tetraacyldisaccharide 4'-kinase activity
FY136_21410	COG2373	Large extracellular alpha-helical protein
FY136_21415	COG4953	penicillin-binding protein 1C
FY136_21430	COG1129	ABC transporter
FY136_21435	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_21455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY136_21465	COG1012	belongs to the aldehyde dehydrogenase family
FY136_21470	COG0673	inositol 2-dehydrogenase activity
FY136_21475	COG3962	Belongs to the TPP enzyme family
FY136_21485	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_21495	COG0673	inositol 2-dehydrogenase activity
FY136_21550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_21555	COG1609	Transcriptional regulator
FY136_21560	COG4209	transmembrane transport
FY136_21565	COG0395	ABC-type sugar transport system, permease component
FY136_21575	COG1397	ADP-ribosylglycohydrolase
FY136_21580	COG3842	ATPase activity
FY136_21600	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_21605	COG0577	efflux transmembrane transporter activity
FY136_21605	COG1136	(ABC) transporter
FY136_21615	COG1733	regulation of RNA biosynthetic process
FY136_21630	COG2072	flavoprotein involved in K transport
FY136_21635	COG0583	DNA-binding transcription factor activity
FY136_21640	COG1472	Belongs to the glycosyl hydrolase 3 family
FY136_21645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY136_21655	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_21660	COG3842	ATPase activity
FY136_21695	COG4691	Plasmid stability protein
FY136_21725	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY136_21730	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_21765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY136_21905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_21910	COG0765	amino acid transport
FY136_21915	COG1126	abc transporter atp-binding protein
FY136_21930	COG2963	transposase activity
FY136_21935	COG3436	PFAM IS66 Orf2 family protein
FY136_21940	COG4372	Transposase
FY136_21945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY136_21985	COG1063	alcohol dehydrogenase
FY136_22035	COG2801	Transposase and inactivated derivatives
FY136_22040	COG1473	amidohydrolase
FY136_22045	COG1686	Belongs to the peptidase S11 family
FY136_22050	COG0523	cobalamin synthesis protein
FY136_22055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY136_22055	COG0425	Belongs to the sulfur carrier protein TusA family
FY136_22060	COG3034	peptidoglycan biosynthetic process
FY136_22065	COG0825	malonyl-CoA metabolic process
FY136_22070	COG4974	Belongs to the 'phage' integrase family
FY136_22080	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY136_22085	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY136_22120	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY136_22125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY136_22140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY136_22145	COG2226	methyltransferase
FY136_22150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY136_22155	COG0287	Prephenate dehydrogenase
FY136_22165	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY136_22185	COG2884	Cell division ATP-binding protein ftsE
FY136_22220	COG0165	Argininosuccinate lyase
FY136_22225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY136_22235	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY136_22245	COG2086	electron transfer activity
FY136_22265	COG0300	oxidoreductase activity
FY136_22275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY136_22285	COG3800	Transcriptional regulator
FY136_22285	COG1396	sequence-specific DNA binding
FY136_22290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY136_22295	COG0625	glutathione transferase activity
FY136_22305	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY136_22315	COG4770	biotin carboxylase activity
FY136_22320	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY136_22320	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY136_22325	COG0346	lactoylglutathione lyase activity
FY136_22340	COG4213	ABC transporter substrate-binding protein
FY136_22345	COG4214	carbohydrate transport
FY136_22350	COG1129	ABC transporter
FY136_22355	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY136_22365	COG1396	sequence-specific DNA binding
FY136_22420	COG3833	ABC-type maltose transport systems, permease component
FY136_22425	COG3842	ATPase activity
FY136_22440	COG2273	Hydrolase Family 16
FY136_22440	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY136_22445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY136_22460	COG0438	transferase activity, transferring glycosyl groups
FY136_22465	COG0438	transferase activity, transferring glycosyl groups
FY136_22485	COG3206	protein involved in exopolysaccharide biosynthesis
FY136_22485	COG0489	protein tyrosine kinase activity
FY136_22495	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY136_22510	COG2244	polysaccharide biosynthetic process
FY136_22525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FY136_22555	COG1733	regulation of RNA biosynthetic process
FY136_22590	COG0653	protein targeting
FY136_22595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY136_22600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY136_22610	COG0494	nUDIX hydrolase
FY136_22625	COG2226	methyltransferase
FY136_22630	COG1040	competence protein
FY136_22640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY136_22655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY136_22670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY136_22685	COG4208	sulfate ABC transporter
FY136_22690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY136_22695	COG4335	DNA alkylation repair
FY136_22710	COG5001	Diguanylate cyclase
FY136_22715	COG2264	protein methyltransferase activity
FY136_22730	COG3254	rhamnose metabolic process
FY136_22740	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_22745	COG1129	ABC transporter
FY136_22755	COG1349	DNA-binding transcription factor activity
FY136_22760	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_22760	COG3347	Dehydrogenase
FY136_22765	COG4952	isomerase
FY136_22770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY136_22775	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY136_22780	COG1024	Enoyl-CoA hydratase
FY136_22795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY136_22800	COG1960	acyl-CoA dehydrogenase activity
FY136_22810	COG0183	Belongs to the thiolase family
FY136_22815	COG1960	acyl-CoA dehydrogenase activity
FY136_22825	COG0022	dehydrogenase e1 component
FY136_22835	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY136_22840	COG2391	methyltransferase activity
FY136_22850	COG0640	Transcriptional regulator
FY136_22855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY136_22855	COG3453	Protein conserved in bacteria
FY136_22860	COG2186	Transcriptional regulator
FY136_22870	COG0601	transmembrane transport
FY136_22880	COG0444	Belongs to the ABC transporter superfamily
FY136_22885	COG4608	Belongs to the ABC transporter superfamily
FY136_22905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_22910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_22925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_22930	COG1473	amidohydrolase
FY136_22935	COG0747	negative chemotaxis
FY136_22950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_22955	COG0583	DNA-binding transcription factor activity
FY136_22965	COG0667	Aldo Keto reductase
FY136_23000	COG1960	acyl-CoA dehydrogenase activity
FY136_23030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY136_23040	COG1959	2 iron, 2 sulfur cluster binding
FY136_23045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_23050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_23055	COG1473	amidohydrolase
FY136_23065	COG1126	abc transporter atp-binding protein
FY136_23070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_23080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_23085	COG1522	sequence-specific DNA binding
FY136_23090	COG4172	Belongs to the ABC transporter superfamily
FY136_23095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_23135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_23140	COG1012	belongs to the aldehyde dehydrogenase family
FY136_23145	COG0473	3-isopropylmalate dehydrogenase activity
FY136_23150	COG1012	belongs to the aldehyde dehydrogenase family
FY136_23160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY136_23165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY136_23180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_23185	COG1120	ATPase activity
FY136_23195	COG2226	methyltransferase
FY136_23210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_23215	COG1120	ATPase activity
FY136_23220	COG1595	DNA-templated transcription, initiation
FY136_23240	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY136_23245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_23265	COG0673	inositol 2-dehydrogenase activity
FY136_23270	COG0673	inositol 2-dehydrogenase activity
FY136_23280	COG1175	transmembrane transport
FY136_23285	COG0395	ABC-type sugar transport system, permease component
FY136_23290	COG3842	ATPase activity
FY136_23300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY136_23305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY136_23310	COG2197	response regulator
FY136_23315	COG0601	transmembrane transport
FY136_23320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_23340	COG0747	negative chemotaxis
FY136_23355	COG1446	asparaginase
FY136_23360	COG0583	DNA-binding transcription factor activity
FY136_23365	COG0601	transmembrane transport
FY136_23390	COG1473	amidohydrolase
FY136_23400	COG1129	ABC transporter
FY136_23405	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_23410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY136_23415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY136_23425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY136_23440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_23450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_23455	COG2079	MmgE PrpD family protein
FY136_23460	COG1126	abc transporter atp-binding protein
FY136_23465	COG0765	amino acid transport
FY136_23480	COG0280	phosphate acetyltransferase
FY136_23480	COG0281	malic enzyme
FY136_23500	COG1175	transmembrane transport
FY136_23505	COG0395	ABC-type sugar transport system, permease component
FY136_23520	COG0673	inositol 2-dehydrogenase activity
FY136_23525	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY136_23530	COG0720	synthase
FY136_23535	COG0602	queuosine metabolic process
FY136_23540	COG0673	inositol 2-dehydrogenase activity
FY136_23550	COG3842	ATPase activity
FY136_23565	COG1653	transport
FY136_23570	COG1609	Transcriptional regulator
FY136_23580	COG2094	Belongs to the DNA glycosylase MPG family
FY136_23590	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_23600	COG1376	ErfK ybiS ycfS ynhG family protein
FY136_23605	COG0840	transmembrane signaling receptor activity
FY136_23610	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY136_23620	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY136_23625	COG1596	polysaccharide export
FY136_23630	COG3307	-O-antigen
FY136_23660	COG2197	response regulator
FY136_23670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY136_23695	COG2942	2-epimerase
FY136_23705	COG1215	transferase activity, transferring glycosyl groups
FY136_23725	COG1473	amidohydrolase
FY136_23735	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_23740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY136_23750	COG1301	dicarboxylic acid transport
FY136_23755	COG4191	Histidine kinase
FY136_23760	COG2204	response regulator
FY136_23770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_23775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY136_23780	COG1522	sequence-specific DNA binding
FY136_23785	COG0351	phosphomethylpyrimidine kinase
FY136_23790	COG0352	thiamine-phosphate diphosphorylase activity
FY136_23795	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY136_23800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_23805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_23810	COG1501	Belongs to the glycosyl hydrolase 31 family
FY136_23815	COG0395	ABC-type sugar transport system, permease component
FY136_23820	COG1175	transmembrane transport
FY136_23825	COG1653	transport
FY136_23830	COG3842	ATPase activity
FY136_23845	COG4989	oxidoreductase activity
FY136_23880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_23885	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY136_23890	COG0438	transferase activity, transferring glycosyl groups
FY136_23895	COG0747	negative chemotaxis
FY136_23900	COG0601	transmembrane transport
FY136_23910	COG3964	amidohydrolase
FY136_23925	COG1921	L-seryl-tRNASec selenium transferase activity
FY136_23935	COG0625	glutathione transferase activity
FY136_23950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_23955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_23955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY136_23960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY136_23980	COG1312	Catalyzes the dehydration of D-mannonate
FY136_23985	COG1063	alcohol dehydrogenase
FY136_23990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_24000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY136_24005	COG2186	Transcriptional regulator
FY136_24010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY136_24015	COG0850	regulation of cytokinetic process
FY136_24020	COG2894	cell division
FY136_24025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY136_24035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_24040	COG5001	Diguanylate cyclase
FY136_24055	COG0673	inositol 2-dehydrogenase activity
FY136_24065	COG1653	transport
FY136_24070	COG1175	transmembrane transport
FY136_24075	COG0395	ABC-type sugar transport system, permease component
FY136_24080	COG3842	ATPase activity
FY136_24090	COG0673	inositol 2-dehydrogenase activity
FY136_24120	COG0587	DNA-directed DNA polymerase activity
FY136_24125	COG2226	methyltransferase
FY136_24140	COG0523	cobalamin synthesis protein
FY136_24145	COG1121	(ABC) transporter
FY136_24155	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY136_24160	COG0328	RNA-DNA hybrid ribonuclease activity
FY136_24170	COG0626	cystathionine gamma-synthase activity
FY136_24175	COG2182	Extracellular solute-binding protein
FY136_24180	COG1175	transmembrane transport
FY136_24185	COG0395	ABC-type sugar transport system, permease component
FY136_24200	COG0395	ABC-type sugar transport system, permease component
FY136_24205	COG1175	transmembrane transport
FY136_24210	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY136_24215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY136_24225	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_24230	COG1063	alcohol dehydrogenase
FY136_24235	COG1609	Transcriptional regulator
FY136_24250	COG2084	Dehydrogenase
FY136_24255	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY136_24265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY136_24270	COG0583	DNA-binding transcription factor activity
FY136_24275	COG2223	nitrite transmembrane transporter activity
FY136_24280	COG4977	sequence-specific DNA binding
FY136_24310	COG0667	Aldo Keto reductase
FY136_24325	COG2186	Transcriptional regulator
FY136_24330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY136_24335	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY136_24340	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_24345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_24350	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_24355	COG3618	amidohydrolase
FY136_24365	COG1175	transmembrane transport
FY136_24370	COG0395	ABC-type sugar transport system, permease component
FY136_24375	COG3842	ATPase activity
FY136_24390	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY136_24415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY136_24420	COG0577	efflux transmembrane transporter activity
FY136_24420	COG1136	(ABC) transporter
FY136_24440	COG1278	Cold shock
FY136_24445	COG0673	inositol 2-dehydrogenase activity
FY136_24460	COG0673	inositol 2-dehydrogenase activity
FY136_24465	COG1309	transcriptional regulator
FY136_24470	COG1653	transport
FY136_24475	COG1175	transmembrane transport
FY136_24480	COG0395	ABC-type sugar transport system, permease component
FY136_24485	COG3842	ATPase activity
FY136_24490	COG1082	Xylose isomerase domain protein TIM barrel
FY136_24495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY136_24505	COG1609	Transcriptional regulator
FY136_24535	COG1175	transmembrane transport
FY136_24540	COG0395	ABC-type sugar transport system, permease component
FY136_24545	COG3842	ATPase activity
FY136_24550	COG0395	ABC-type sugar transport system, permease component
FY136_24555	COG1175	transmembrane transport
FY136_24560	COG1653	transport
FY136_24590	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FY136_24620	COG3842	ATPase activity
FY136_24630	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_24635	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_24660	COG5001	Diguanylate cyclase
FY136_24665	COG2233	PERMEase
FY136_24670	COG0583	DNA-binding transcription factor activity
FY136_24675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY136_24685	COG0583	DNA-binding transcription factor activity
FY136_24690	COG2828	Protein conserved in bacteria
FY136_24705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_24710	COG3734	2-keto-3-deoxy-galactonokinase
FY136_24715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY136_24720	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_24730	COG1175	transmembrane transport
FY136_24735	COG0395	ABC-type sugar transport system, permease component
FY136_24740	COG3842	ATPase activity
FY136_24745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY136_24750	COG1414	Transcriptional regulator
FY136_24755	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_24760	COG0483	inositol monophosphate 1-phosphatase activity
FY136_24770	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY136_24775	COG0395	ABC-type sugar transport system, permease component
FY136_24790	COG0840	transmembrane signaling receptor activity
FY136_24795	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY136_24830	COG1175	transmembrane transport
FY136_24835	COG3842	ATPase activity
FY136_24905	COG0640	Transcriptional regulator
FY136_24990	COG1595	DNA-templated transcription, initiation
FY136_24995	COG0110	maltose O-acetyltransferase activity
FY136_25010	COG0583	DNA-binding transcription factor activity
FY136_25020	COG2814	Major facilitator Superfamily
FY136_25055	COG0640	Transcriptional regulator
FY136_25065	COG1192	Involved in chromosome partitioning
FY136_25070	COG1475	DNA binding
FY136_25075	COG0640	Transcriptional regulator
FY136_25090	COG1126	abc transporter atp-binding protein
FY136_25095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY136_25100	COG1609	Transcriptional regulator
FY136_25135	COG3239	Fatty acid desaturase
FY136_25145	COG1278	Cold shock
FY136_25225	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY136_25225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY136_25260	COG4191	Histidine kinase
FY136_25265	COG1132	(ABC) transporter
FY136_25275	COG0640	Transcriptional regulator
FY136_25305	COG4977	sequence-specific DNA binding
FY136_25310	COG2211	Major facilitator Superfamily
FY136_25315	COG2807	transmembrane transport
FY136_25320	COG1846	Transcriptional regulator
FY136_25335	COG2814	Major facilitator Superfamily
FY136_25365	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY136_25380	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY136_25385	COG0583	DNA-binding transcription factor activity
FY136_25400	COG0071	Belongs to the small heat shock protein (HSP20) family
FY136_25450	COG3838	Conjugal transfer protein Trbc
FY136_25455	COG3702	type iv secretory pathway
FY136_25460	COG3451	type IV secretory pathway VirB4
FY136_25475	COG3704	protein secretion by the type IV secretion system
FY136_25485	COG3736	Type IV secretory pathway, component VirB8
FY136_25490	COG3504	Conjugal transfer protein
FY136_25495	COG2948	multi-organism process
FY136_25500	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY136_25600	COG3831	ATPase activity
FY136_25615	COG3505	Type IV secretory pathway VirD4
FY136_25640	COG0583	DNA-binding transcription factor activity
FY136_25680	COG0745	RESPONSE REGULATOR receiver
FY136_25720	COG3842	ATPase activity
FY136_25725	COG4208	sulfate ABC transporter
FY136_25730	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_25755	COG1942	4-Oxalocrotonate Tautomerase
FY136_25765	COG3971	2-oxopent-4-enoate hydratase activity
FY136_25775	COG1414	Transcriptional regulator
FY136_25785	COG1137	ATPase activity
FY136_25800	COG4177	L-phenylalanine transmembrane transporter activity
FY136_25820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY136_25825	COG1175	transmembrane transport
FY136_25830	COG0395	ABC-type sugar transport system, permease component
FY136_25840	COG0366	Alpha amylase catalytic
FY136_25845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY136_25850	COG1082	Xylose isomerase domain protein TIM barrel
FY136_25855	COG3842	ATPase activity
FY136_25865	COG1940	carbohydrate kinase activity
FY136_25870	COG0395	ABC-type sugar transport system, permease component
FY136_25880	COG2182	Extracellular solute-binding protein
FY136_25885	COG0673	inositol 2-dehydrogenase activity
FY136_25915	COG1126	abc transporter atp-binding protein
FY136_25920	COG0765	amino acid transport
FY136_25925	COG0765	amino acid transport
FY136_25935	COG4608	Belongs to the ABC transporter superfamily
FY136_25945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_25960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY136_25965	COG0583	DNA-binding transcription factor activity
FY136_25970	COG2423	ornithine cyclodeaminase activity
FY136_25980	COG1957	nucleoside hydrolase
FY136_25995	COG1335	isochorismatase
FY136_26000	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_26045	COG0583	DNA-binding transcription factor activity
FY136_26050	COG1902	pentaerythritol trinitrate reductase activity
FY136_26055	COG0583	DNA-binding transcription factor activity
FY136_26060	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_26070	COG1335	isochorismatase
FY136_26075	COG0583	DNA-binding transcription factor activity
FY136_26085	COG1695	Transcriptional regulator
FY136_26165	COG2207	Transcriptional regulator
FY136_26210	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_26225	COG1802	Transcriptional regulator
FY136_26230	COG3485	protocatechuate 3,4-dioxygenase
FY136_26235	COG3971	2-oxopent-4-enoate hydratase activity
FY136_26250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY136_26255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY136_26270	COG1063	alcohol dehydrogenase
FY136_26280	COG1960	acyl-CoA dehydrogenase activity
FY136_26285	COG1024	Enoyl-CoA hydratase
FY136_26295	COG1012	belongs to the aldehyde dehydrogenase family
FY136_26300	COG0477	Major facilitator Superfamily
FY136_26320	COG1940	carbohydrate kinase activity
FY136_26330	COG1879	ABC-type sugar transport system periplasmic component
FY136_26340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_26355	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY136_26365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY136_26370	COG0563	adenylate kinase activity
FY136_26425	COG3706	GGDEF domain
FY136_26445	COG1846	Transcriptional regulator
FY136_26485	COG1012	belongs to the aldehyde dehydrogenase family
FY136_26495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY136_26505	COG3386	PFAM SMP-30 Gluconolaconase
FY136_26510	COG3622	Belongs to the hyi family
FY136_26515	COG2084	Dehydrogenase
FY136_26540	COG1940	carbohydrate kinase activity
FY136_26545	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_26555	COG1129	ABC transporter
FY136_26580	COG0583	DNA-binding transcription factor activity
FY136_26585	COG2271	Major facilitator Superfamily
FY136_26595	COG2272	Belongs to the type-B carboxylesterase lipase family
FY136_26615	COG1129	ABC transporter
FY136_26640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY136_26650	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY136_26685	COG0583	DNA-binding transcription factor activity
FY136_26690	COG1414	Transcriptional regulator
FY136_26700	COG4948	Mandelate Racemase Muconate Lactonizing
FY136_26710	COG3842	ATPase activity
FY136_26715	COG1175	transmembrane transport
FY136_26720	COG0395	ABC-type sugar transport system, permease component
FY136_26730	COG0477	Major facilitator Superfamily
FY136_26765	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY136_26785	COG0747	negative chemotaxis
FY136_26795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_26810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_26820	COG4215	(ABC) transporter
FY136_26875	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY136_26880	COG0251	oxidation-reduction process
FY136_26885	COG3547	Transposase (IS116 IS110 IS902 family)
FY136_26920	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_26925	COG1335	isochorismatase
FY136_26935	COG1309	transcriptional regulator
FY136_26940	COG4604	ABC transporter, ATP-binding protein
FY136_26945	COG4605	iron ion homeostasis
FY136_26950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY136_26960	COG2132	Multicopper oxidase
FY136_26965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY136_26970	COG4771	TonB-dependent receptor
FY136_27010	COG1695	Transcriptional regulator
FY136_27045	COG2132	Multicopper oxidase
FY136_27075	COG0583	DNA-binding transcription factor activity
FY136_27080	COG1741	Belongs to the pirin family
FY136_27085	COG1902	pentaerythritol trinitrate reductase activity
FY136_27095	COG1335	isochorismatase
FY136_27105	COG3344	reverse transcriptase
FY136_27135	COG3621	Patatin-like phospholipase
FY136_27140	COG1396	sequence-specific DNA binding
FY136_27150	COG0583	DNA-binding transcription factor activity
FY136_27155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_27160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_27165	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
FY136_27170	COG0601	transmembrane transport
FY136_27175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_27180	COG4172	Belongs to the ABC transporter superfamily
FY136_27185	COG0747	negative chemotaxis
FY136_27205	COG1129	ABC transporter
FY136_27210	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_27220	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY136_27245	COG4716	Myosin-crossreactive antigen
FY136_27250	COG1196	nuclear chromosome segregation
FY136_27270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_27285	COG0583	DNA-binding transcription factor activity
FY136_27335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY136_27345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY136_27365	COG1192	Involved in chromosome partitioning
FY136_27370	COG1475	DNA binding
FY136_27375	COG0640	Transcriptional regulator
FY136_27380	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY136_27425	COG0583	DNA-binding transcription factor activity
FY136_27435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY136_27440	COG1116	anion transmembrane transporter activity
FY136_27445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY136_27455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_27460	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_27490	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY136_27495	COG1129	ABC transporter
FY136_27520	COG4172	Belongs to the ABC transporter superfamily
FY136_27525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_27530	COG0601	transmembrane transport
FY136_27540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_27545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY136_27550	COG0583	DNA-binding transcription factor activity
FY136_27560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY136_27575	COG1132	(ABC) transporter
FY136_27580	COG4172	Belongs to the ABC transporter superfamily
FY136_27585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_27605	COG1082	Xylose isomerase domain protein TIM barrel
FY136_27610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY136_27615	COG0019	diaminopimelate decarboxylase activity
FY136_27625	COG1475	DNA binding
FY136_27635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY136_27730	COG1475	DNA binding
FY136_27755	COG2824	Alkylphosphonate utilization operon protein PhnA
FY136_27805	COG5489	Protein of unknown function (DUF736)
FY136_27890	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY136_27905	COG0747	negative chemotaxis
FY136_27910	COG0444	Belongs to the ABC transporter superfamily
FY136_27925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_27930	COG0584	glycerophosphoryl diester phosphodiesterase
FY136_27935	COG0483	inositol monophosphate 1-phosphatase activity
FY136_28000	COG3161	chorismate lyase activity
FY136_28150	COG3436	PFAM IS66 Orf2 family protein
FY136_28230	COG2222	sugar isomerase
FY136_28240	COG0006	proline dipeptidase activity
FY136_28260	COG1177	transmembrane transport
FY136_28265	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY136_28270	COG3842	ATPase activity
FY136_28300	COG3842	ATPase activity
FY136_28305	COG0006	proline dipeptidase activity
FY136_28325	COG0300	oxidoreductase activity
FY136_28330	COG0129	dihydroxy-acid dehydratase activity
FY136_28335	COG0667	Aldo Keto reductase
FY136_28345	COG1028	Short-chain dehydrogenase reductase Sdr
FY136_28355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_28360	COG0601	transmembrane transport
FY136_28365	COG4172	Belongs to the ABC transporter superfamily
FY136_28375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY136_28410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY136_28445	COG3701	Conjugal transfer protein
FY136_28450	COG3846	protein secretion by the type IV secretion system
FY136_28460	COG5314	conjugation
FY136_28465	COG3451	type IV secretory pathway VirB4
FY136_28480	COG4962	Type ii secretion system protein e
FY136_28630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY136_28635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY136_28650	COG1793	dna ligase
FY136_28930	COG1674	ftsk spoiiie
FY136_28950	COG3704	protein secretion by the type IV secretion system
FY136_29005	COG1192	Involved in chromosome partitioning
FY136_29035	COG1192	Involved in chromosome partitioning
FY136_29075	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs