locus-tag	class	description
MLE07_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MLE07_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MLE07_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MLE07_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MLE07_00025	COG1420	regulation of RNA biosynthetic process
MLE07_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MLE07_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLE07_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MLE07_00050	COG1137	ATPase activity
MLE07_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MLE07_00065	COG0616	signal peptide processing
MLE07_00070	COG0776	regulation of translation
MLE07_00080	COG0116	Belongs to the methyltransferase superfamily
MLE07_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MLE07_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLE07_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MLE07_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MLE07_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MLE07_00115	COG0728	peptidoglycan biosynthetic process
MLE07_00125	COG0180	Tryptophanyl-tRNA synthetase
MLE07_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MLE07_00140	COG1214	PFAM Peptidase M22, glycoprotease
MLE07_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLE07_00165	COG1702	phosphate starvation-inducible protein PhoH
MLE07_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MLE07_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MLE07_00185	COG1396	sequence-specific DNA binding
MLE07_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MLE07_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MLE07_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_00210	COG0242	peptide deformylase activity
MLE07_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MLE07_00220	COG0101	tRNA pseudouridine synthase activity
MLE07_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MLE07_00235	COG2171	N-acyltransferase activity
MLE07_00245	COG0840	transmembrane signaling receptor activity
MLE07_00250	COG1957	nucleoside hydrolase
MLE07_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
MLE07_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MLE07_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MLE07_00295	COG0706	membrane insertase activity
MLE07_00300	COG0594	ribonuclease P activity
MLE07_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MLE07_00310	COG0840	transmembrane signaling receptor activity
MLE07_00325	COG2226	methyltransferase
MLE07_00330	COG3842	ATPase activity
MLE07_00335	COG1175	transmembrane transport
MLE07_00340	COG0395	ABC-type sugar transport system, permease component
MLE07_00355	COG0427	acetyl-CoA hydrolase
MLE07_00365	COG3938	Belongs to the proline racemase family
MLE07_00370	COG0418	dihydroorotase activity
MLE07_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLE07_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLE07_00400	COG0166	Belongs to the GPI family
MLE07_00405	COG0318	PFAM AMP-dependent synthetase and ligase
MLE07_00410	COG3842	ATPase activity
MLE07_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
MLE07_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MLE07_00425	COG4774	siderophore transport
MLE07_00470	COG2326	polyphosphate kinase activity
MLE07_00475	COG5002	protein histidine kinase activity
MLE07_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MLE07_00485	COG0573	inorganic phosphate transmembrane transporter activity
MLE07_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MLE07_00500	COG0704	Plays a role in the regulation of phosphate uptake
MLE07_00505	COG0745	RESPONSE REGULATOR receiver
MLE07_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MLE07_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MLE07_00530	COG2967	ApaG domain
MLE07_00540	COG0717	Belongs to the dCTP deaminase family
MLE07_00625	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MLE07_00630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MLE07_00680	COG0167	dihydroorotate dehydrogenase activity
MLE07_00695	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MLE07_00715	COG1959	2 iron, 2 sulfur cluster binding
MLE07_00720	COG1201	RNA secondary structure unwinding
MLE07_00750	COG1960	acyl-CoA dehydrogenase activity
MLE07_00755	COG0183	Belongs to the thiolase family
MLE07_00760	COG1024	Enoyl-CoA hydratase
MLE07_00760	COG1250	3-hydroxyacyl-CoA dehydrogenase
MLE07_00780	COG1320	monovalent cation:proton antiporter activity
MLE07_00785	COG2212	antiporter activity
MLE07_00790	COG1863	multisubunit Na H antiporter MnhE subunit
MLE07_00795	COG0651	ATP synthesis coupled electron transport
MLE07_00800	COG1006	Multisubunit Na H antiporter MnhC subunit
MLE07_00805	COG2111	Na H antiporter
MLE07_00805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MLE07_00815	COG0840	transmembrane signaling receptor activity
MLE07_00825	COG0745	RESPONSE REGULATOR receiver
MLE07_00830	COG2198	Histidine kinase
MLE07_00830	COG0643	Histidine kinase
MLE07_00835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MLE07_00840	COG2201	protein-glutamate methylesterase activity
MLE07_00845	COG0745	RESPONSE REGULATOR receiver
MLE07_00850	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
MLE07_00860	COG1766	The M ring may be actively involved in energy transduction
MLE07_00865	COG2771	luxR family
MLE07_00875	COG2972	Histidine kinase
MLE07_00875	COG0840	transmembrane signaling receptor activity
MLE07_00880	COG2205	protein histidine kinase activity
MLE07_00880	COG0784	Response regulator, receiver
MLE07_00880	COG2198	Histidine kinase
MLE07_00885	COG1970	mechanosensitive ion channel activity
MLE07_00890	COG0436	Aminotransferase
MLE07_00905	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MLE07_00910	COG0424	maF-like protein
MLE07_00915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MLE07_00925	COG5328	Belongs to the UPF0262 family
MLE07_00930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MLE07_00940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MLE07_00960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MLE07_00970	COG1338	Plays a role in the flagellum-specific transport system
MLE07_00980	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MLE07_00990	COG1706	bacterial-type flagellum-dependent cell motility
MLE07_00995	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MLE07_01000	COG4786	Flagellar basal body rod
MLE07_01005	COG1677	Flagellar hook-basal body complex protein FliE
MLE07_01010	COG1558	bacterial-type flagellum-dependent cell motility
MLE07_01015	COG1815	bacterial-type flagellum-dependent cell motility
MLE07_01025	COG1157	protein secretion by the type III secretion system
MLE07_01030	COG4786	Flagellar basal body rod
MLE07_01040	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
MLE07_01045	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLE07_01050	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLE07_01055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MLE07_01060	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLE07_01080	COG1360	Flagellar Motor Protein
MLE07_01105	COG1749	Flagellar hook protein flgE
MLE07_01125	COG5443	negative regulation of bacterial-type flagellum assembly
MLE07_01130	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
MLE07_01140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MLE07_01180	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLE07_01185	COG1609	Transcriptional regulator
MLE07_01190	COG1653	transport
MLE07_01195	COG1175	transmembrane transport
MLE07_01200	COG0395	ABC-type sugar transport system, permease component
MLE07_01205	COG0366	Alpha amylase catalytic
MLE07_01210	COG3842	ATPase activity
MLE07_01225	COG0129	dihydroxy-acid dehydratase activity
MLE07_01230	COG0363	glucosamine-6-phosphate deaminase activity
MLE07_01235	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MLE07_01245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_01255	COG2081	HI0933 family
MLE07_01275	COG2224	Isocitrate lyase
MLE07_01290	COG3842	ATPase activity
MLE07_01295	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLE07_01300	COG1177	transmembrane transport
MLE07_01310	COG2205	protein histidine kinase activity
MLE07_01320	COG0248	Ppx GppA phosphatase
MLE07_01325	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MLE07_01330	COG0477	Major facilitator Superfamily
MLE07_01360	COG0521	Mo-molybdopterin cofactor biosynthetic process
MLE07_01365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MLE07_01375	COG0142	geranyltranstransferase activity
MLE07_01400	COG0752	glycyl-tRNA synthetase alpha subunit
MLE07_01410	COG1704	LemA family
MLE07_01415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MLE07_01425	COG0751	glycine-tRNA ligase activity
MLE07_01430	COG1683	Conserved Protein
MLE07_01435	COG0840	transmembrane signaling receptor activity
MLE07_01445	COG0151	Belongs to the GarS family
MLE07_01450	COG2183	response to ionizing radiation
MLE07_01455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MLE07_01480	COG0583	DNA-binding transcription factor activity
MLE07_01500	COG0306	phosphate transporter
MLE07_01510	COG0561	phosphatase activity
MLE07_01515	COG0438	transferase activity, transferring glycosyl groups
MLE07_01520	COG2186	Transcriptional regulator
MLE07_01535	COG0583	DNA-binding transcription factor activity
MLE07_01540	COG0277	FAD linked oxidase domain protein
MLE07_01545	COG0277	FAD linked oxidase domain protein
MLE07_01550	COG0247	lactate metabolic process
MLE07_01560	COG1376	ErfK ybiS ycfS ynhG family protein
MLE07_01565	COG2818	Glycosylase
MLE07_01575	COG2855	membrane
MLE07_01580	COG0583	DNA-binding transcription factor activity
MLE07_01610	COG0124	histidyl-tRNA synthetase
MLE07_01620	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MLE07_01625	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MLE07_01630	COG2259	Doxx family
MLE07_01640	COG0459	protein refolding
MLE07_01645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MLE07_01655	COG0196	riboflavin kinase activity
MLE07_01660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MLE07_01670	COG0590	tRNA wobble adenosine to inosine editing
MLE07_01675	COG1187	pseudouridine synthase activity
MLE07_01680	COG0742	ribosomal rna small subunit methyltransferase
MLE07_01685	COG1752	Esterase of the alpha-beta hydrolase superfamily
MLE07_01695	COG0312	modulator of DNA gyrase
MLE07_01700	COG0483	inositol monophosphate 1-phosphatase activity
MLE07_01710	COG1519	Transferase
MLE07_01720	COG1663	tetraacyldisaccharide 4'-kinase activity
MLE07_01730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MLE07_01735	COG0745	RESPONSE REGULATOR receiver
MLE07_01740	COG3300	MHYT domain
MLE07_01740	COG5001	Diguanylate cyclase
MLE07_01745	COG3386	PFAM SMP-30 Gluconolaconase
MLE07_01750	COG0800	Aldolase
MLE07_01755	COG3734	2-keto-3-deoxy-galactonokinase
MLE07_01760	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_01765	COG1414	Transcriptional regulator
MLE07_01770	COG2197	response regulator
MLE07_01785	COG0598	Magnesium transport protein CorA
MLE07_01790	COG3158	transport of potassium into the cell
MLE07_01805	COG0356	it plays a direct role in the translocation of protons across the membrane
MLE07_01815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLE07_01820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MLE07_01835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MLE07_01855	COG0009	L-threonylcarbamoyladenylate synthase
MLE07_01865	COG4638	Rieske (2fe-2S)
MLE07_01890	COG1960	acyl-CoA dehydrogenase activity
MLE07_01905	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MLE07_01910	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MLE07_01915	COG0840	transmembrane signaling receptor activity
MLE07_01925	COG1522	sequence-specific DNA binding
MLE07_01950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MLE07_01955	COG1741	Belongs to the pirin family
MLE07_01960	COG1722	exodeoxyribonuclease VII activity
MLE07_01965	COG0123	including yeast histone deacetylase and acetoin utilization protein
MLE07_01970	COG1268	BioY protein
MLE07_01975	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MLE07_01980	COG1122	ATPase activity
MLE07_01985	COG3214	Protein conserved in bacteria
MLE07_01990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLE07_01990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLE07_01995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MLE07_02010	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MLE07_02025	COG0259	pyridoxamine-phosphate oxidase activity
MLE07_02045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MLE07_02055	COG0312	modulator of DNA gyrase
MLE07_02070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLE07_02075	COG0109	protoheme IX farnesyltransferase activity
MLE07_02080	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
MLE07_02095	COG3346	SURF1 family
MLE07_02100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MLE07_02105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MLE07_02110	COG0328	RNA-DNA hybrid ribonuclease activity
MLE07_02120	COG0678	peroxiredoxin activity
MLE07_02120	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MLE07_02130	COG1678	Uncharacterized ACR, COG1678
MLE07_02145	COG3300	MHYT domain
MLE07_02145	COG5001	Diguanylate cyclase
MLE07_02150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MLE07_02155	COG0612	Peptidase, M16
MLE07_02180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MLE07_02185	COG1802	Transcriptional regulator
MLE07_02205	COG2189	Belongs to the N(4) N(6)-methyltransferase family
MLE07_02210	COG3609	addiction module antidote protein, CC2985 family
MLE07_02215	COG3668	Plasmid stabilization system
MLE07_02225	COG1194	a g-specific adenine glycosylase
MLE07_02240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MLE07_02245	COG1196	nuclear chromosome segregation
MLE07_02250	COG2514	catechol 2,3-dioxygenase activity
MLE07_02255	COG0574	Belongs to the PEP-utilizing enzyme family
MLE07_02255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MLE07_02265	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MLE07_02270	COG1823	symporter activity
MLE07_02295	COG0579	oxidoreductase
MLE07_02315	COG2895	sulfate adenylyltransferase (ATP) activity
MLE07_02320	COG0175	sulfate reduction
MLE07_02325	COG0175	sulfate reduction
MLE07_02330	COG1959	2 iron, 2 sulfur cluster binding
MLE07_02335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MLE07_02340	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MLE07_02345	COG4208	sulfate ABC transporter
MLE07_02350	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MLE07_02360	COG2199	diguanylate cyclase activity
MLE07_02360	COG2200	EAL domain
MLE07_02360	COG2203	Gaf domain
MLE07_02370	COG1309	transcriptional regulator
MLE07_02375	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_02380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MLE07_02410	COG0625	glutathione transferase activity
MLE07_02420	COG0477	Major facilitator Superfamily
MLE07_02430	COG3657	addiction module killer protein
MLE07_02440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MLE07_02440	COG1793	dna ligase
MLE07_02460	COG1376	ErfK ybiS ycfS ynhG family protein
MLE07_02465	COG1376	ErfK ybiS ycfS ynhG family protein
MLE07_02470	COG1846	Transcriptional regulator
MLE07_02475	COG1764	response to oxidative stress
MLE07_02490	COG0488	(ABC) transporter
MLE07_02520	COG0583	DNA-binding transcription factor activity
MLE07_02525	COG4221	oxidoreductase activity
MLE07_02540	COG0433	COG0433 Predicted ATPase
MLE07_02550	COG1733	regulation of RNA biosynthetic process
MLE07_02555	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
MLE07_02570	COG0656	L-ascorbic acid biosynthetic process
MLE07_02575	COG3781	membrane
MLE07_02580	COG2378	regulation of single-species biofilm formation
MLE07_02590	COG4106	trans-aconitate 2-methyltransferase activity
MLE07_02595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLE07_02600	COG0840	transmembrane signaling receptor activity
MLE07_02605	COG0583	DNA-binding transcription factor activity
MLE07_02620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLE07_02640	COG3909	cytochrome
MLE07_02645	COG2010	Cytochrome c
MLE07_02680	COG0789	Transcriptional regulator
MLE07_02705	COG0517	IMP dehydrogenase activity
MLE07_02705	COG4175	Glycine betaine
MLE07_02710	COG4176	ABC-type proline glycine betaine transport system permease component
MLE07_02730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_02740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLE07_02740	COG2169	Transcriptional regulator
MLE07_02750	COG2514	catechol 2,3-dioxygenase activity
MLE07_02765	COG1272	protein, Hemolysin III
MLE07_02775	COG1280	lysine exporter protein (LysE YggA)
MLE07_02780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLE07_02785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MLE07_02785	COG2111	Na H antiporter
MLE07_02790	COG2111	Na H antiporter
MLE07_02795	COG1006	Multisubunit Na H antiporter MnhC subunit
MLE07_02800	COG0651	ATP synthesis coupled electron transport
MLE07_02805	COG1863	multisubunit Na H antiporter MnhE subunit
MLE07_02810	COG2212	antiporter activity
MLE07_02815	COG1320	monovalent cation:proton antiporter activity
MLE07_02820	COG4957	zinc ion binding
MLE07_02835	COG2166	iron-sulfur cluster assembly
MLE07_02845	COG2205	protein histidine kinase activity
MLE07_02890	COG0583	DNA-binding transcription factor activity
MLE07_02895	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MLE07_02900	COG2983	Belongs to the UPF0260 family
MLE07_02910	COG3041	Addiction module toxin RelE StbE family
MLE07_02915	COG3077	Addiction module antitoxin, RelB DinJ family
MLE07_02920	COG2217	Heavy metal translocating P-type atpase
MLE07_02950	COG2814	Major facilitator Superfamily
MLE07_02960	COG1621	beta-fructofuranosidase activity
MLE07_02965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MLE07_03015	COG4695	Portal protein
MLE07_03120	COG4235	cytochrome complex assembly
MLE07_03125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MLE07_03130	COG1138	Cytochrome C-type biogenesis protein
MLE07_03135	COG3088	subunit of a heme lyase
MLE07_03140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLE07_03145	COG0745	RESPONSE REGULATOR receiver
MLE07_03150	COG2205	protein histidine kinase activity
MLE07_03155	COG3011	Protein conserved in bacteria
MLE07_03160	COG3713	MltA-interacting MipA family protein
MLE07_03165	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MLE07_03170	COG2205	protein histidine kinase activity
MLE07_03170	COG2202	Pas domain
MLE07_03180	COG0308	aminopeptidase N
MLE07_03185	COG0697	spore germination
MLE07_03200	COG0443	Heat shock 70 kDa protein
MLE07_03235	COG0604	alcohol dehydrogenase
MLE07_03240	COG1733	regulation of RNA biosynthetic process
MLE07_03245	COG1968	undecaprenyl-diphosphatase activity
MLE07_03250	COG2239	Acts as a magnesium transporter
MLE07_03255	COG2814	Major facilitator Superfamily
MLE07_03285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MLE07_03315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLE07_03365	COG0741	lytic transglycosylase activity
MLE07_03370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_03375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MLE07_03380	COG0840	transmembrane signaling receptor activity
MLE07_03390	COG1758	RNA polymerase activity
MLE07_03415	COG0736	holo-[acyl-carrier-protein] synthase activity
MLE07_03420	COG0681	Belongs to the peptidase S26 family
MLE07_03425	COG0571	ribonuclease III activity
MLE07_03430	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MLE07_03440	COG0784	Response regulator, receiver
MLE07_03445	COG1381	Involved in DNA repair and RecF pathway recombination
MLE07_03455	COG2226	methyltransferase
MLE07_03465	COG1418	mRNA catabolic process
MLE07_03475	COG0346	lactoylglutathione lyase activity
MLE07_03490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_03495	COG3443	Belongs to the bacterial solute-binding protein 9 family
MLE07_03500	COG0668	transmembrane transport
MLE07_03510	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MLE07_03540	COG1742	UPF0060 membrane protein
MLE07_03555	COG1183	phosphatidylcholine synthase activity
MLE07_03560	COG0688	phosphatidylethanolamine metabolic process
MLE07_03565	COG5265	(ABC) transporter
MLE07_03605	COG2852	Protein conserved in bacteria
MLE07_03615	COG0215	cysteine-tRNA ligase activity
MLE07_03620	COG4221	oxidoreductase activity
MLE07_03625	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLE07_03630	COG1286	toxin biosynthetic process
MLE07_03650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLE07_03660	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MLE07_03670	COG0305	Participates in initiation and elongation during chromosome replication
MLE07_03690	COG0359	binds to the 23S rRNA
MLE07_03700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MLE07_03705	COG0360	Binds together with S18 to 16S ribosomal RNA
MLE07_03715	COG0667	Aldo Keto reductase
MLE07_03720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MLE07_03730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLE07_03735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MLE07_03745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MLE07_03750	COG1561	YicC-like family, N-terminal region
MLE07_03755	COG0194	GDP metabolic process
MLE07_03760	COG0400	carboxylic ester hydrolase activity
MLE07_03765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MLE07_03770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MLE07_03780	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MLE07_03795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLE07_03815	COG4251	negative regulation of phosphorylation
MLE07_03815	COG3706	GGDEF domain
MLE07_03815	COG5001	Diguanylate cyclase
MLE07_03815	COG2203	Gaf domain
MLE07_03820	COG3300	MHYT domain
MLE07_03820	COG5001	Diguanylate cyclase
MLE07_03825	COG4191	Histidine kinase
MLE07_03830	COG4566	intracellular signal transduction
MLE07_03840	COG0488	(ABC) transporter
MLE07_03845	COG3706	GGDEF domain
MLE07_03855	COG0105	UTP biosynthetic process
MLE07_03875	COG0314	molybdopterin synthase activity
MLE07_03885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MLE07_03890	COG0322	excinuclease ABC activity
MLE07_03895	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_03910	COG3719	Belongs to the RNase T2 family
MLE07_03920	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MLE07_03925	COG0243	molybdopterin cofactor binding
MLE07_03940	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MLE07_03945	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MLE07_03955	COG0628	permease
MLE07_03965	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MLE07_03970	COG0248	Ppx GppA phosphatase
MLE07_03975	COG0110	maltose O-acetyltransferase activity
MLE07_03995	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
MLE07_04005	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MLE07_04010	COG0477	Major facilitator Superfamily
MLE07_04015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MLE07_04025	COG0840	transmembrane signaling receptor activity
MLE07_04030	COG0659	secondary active sulfate transmembrane transporter activity
MLE07_04040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLE07_04045	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MLE07_04055	COG0113	porphobilinogen synthase activity
MLE07_04075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLE07_04080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MLE07_04085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLE07_04085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MLE07_04095	COG1280	lysine exporter protein (LysE YggA)
MLE07_04100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MLE07_04105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLE07_04110	COG2814	Major facilitator Superfamily
MLE07_04115	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
MLE07_04135	COG0416	fatty acid biosynthetic process
MLE07_04140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLE07_04145	COG0776	regulation of translation
MLE07_04180	COG0601	transmembrane transport
MLE07_04185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_04190	COG0444	Belongs to the ABC transporter superfamily
MLE07_04200	COG0747	negative chemotaxis
MLE07_04210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MLE07_04215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLE07_04230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MLE07_04235	COG0583	DNA-binding transcription factor activity
MLE07_04240	COG0737	Belongs to the 5'-nucleotidase family
MLE07_04260	COG2897	thiosulfate sulfurtransferase activity
MLE07_04275	COG0415	Belongs to the DNA photolyase family
MLE07_04285	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLE07_04315	COG3932	Exopolysaccharide synthesis, ExoD
MLE07_04320	COG1238	metal cluster binding
MLE07_04395	COG1612	heme a metabolic process
MLE07_04405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MLE07_04410	COG0010	Belongs to the arginase family
MLE07_04415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MLE07_04420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MLE07_04430	COG1832	CoA-binding protein
MLE07_04440	COG1846	Transcriptional regulator
MLE07_04465	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_04475	COG2199	diguanylate cyclase activity
MLE07_04480	COG0740	serine-type endopeptidase activity
MLE07_04485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MLE07_04490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MLE07_04500	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MLE07_04530	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MLE07_04535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MLE07_04540	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MLE07_04550	COG0649	NAD binding
MLE07_04560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MLE07_04565	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MLE07_04575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MLE07_04580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MLE07_04590	COG0713	ATP synthesis coupled electron transport
MLE07_04605	COG1007	ATP synthesis coupled electron transport
MLE07_04610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MLE07_04610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MLE07_04625	COG0442	prolyl-tRNA aminoacylation
MLE07_04635	COG1136	(ABC) transporter
MLE07_04650	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MLE07_04670	COG0784	Response regulator, receiver
MLE07_04680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MLE07_04685	COG0477	Major facilitator Superfamily
MLE07_04700	COG0557	exoribonuclease II activity
MLE07_04705	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MLE07_04715	COG0758	DNA mediated transformation
MLE07_04720	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MLE07_04730	COG0540	Belongs to the ATCase OTCase family
MLE07_04745	COG1960	acyl-CoA dehydrogenase activity
MLE07_04750	COG0456	acetyltransferase
MLE07_04770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MLE07_04775	COG2824	Alkylphosphonate utilization operon protein PhnA
MLE07_04780	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MLE07_04785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLE07_04790	COG0154	amidase activity
MLE07_04795	COG0456	acetyltransferase
MLE07_04800	COG3811	Belongs to the UPF0386 family
MLE07_04815	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MLE07_04845	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MLE07_04850	COG0439	Biotin carboxylase
MLE07_04855	COG0511	ligase activity, forming carbon-carbon bonds
MLE07_04860	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MLE07_04870	COG0436	Aminotransferase
MLE07_04890	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_04895	COG1530	ribonuclease E activity
MLE07_04905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MLE07_04925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MLE07_04930	COG0384	phenazine biosynthesis protein PhzF
MLE07_04950	COG0633	Ferredoxin
MLE07_04960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MLE07_04965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MLE07_04970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MLE07_04980	COG3768	UPF0283 membrane protein
MLE07_04985	COG3106	COG3106 Predicted ATPase
MLE07_05015	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MLE07_05045	COG0537	adenosine 5'-monophosphoramidase activity
MLE07_05070	COG0052	Belongs to the universal ribosomal protein uS2 family
MLE07_05075	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MLE07_05080	COG0528	UMP kinase activity
MLE07_05085	COG0233	cytoplasmic translational termination
MLE07_05090	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MLE07_05100	COG0750	zinc metalloprotease
MLE07_05105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MLE07_05110	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MLE07_05115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MLE07_05120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MLE07_05125	COG3494	Protein of unknown function (DUF1009)
MLE07_05130	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MLE07_05135	COG2186	Transcriptional regulator
MLE07_05145	COG0765	amino acid transport
MLE07_05150	COG0765	amino acid transport
MLE07_05160	COG0372	Belongs to the citrate synthase family
MLE07_05175	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MLE07_05185	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MLE07_05190	COG0148	phosphopyruvate hydratase activity
MLE07_05200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MLE07_05205	COG0022	dehydrogenase e1 component
MLE07_05205	COG0508	dehydrogenase complex catalyzes the overall conversion of
MLE07_05215	COG0508	dehydrogenase complex catalyzes the overall conversion of
MLE07_05225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MLE07_05235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MLE07_05240	COG0697	spore germination
MLE07_05260	COG2867	negative regulation of translational initiation
MLE07_05265	COG1546	Belongs to the CinA family
MLE07_05270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MLE07_05270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MLE07_05280	COG3852	Histidine kinase
MLE07_05285	COG2204	response regulator
MLE07_05290	COG5000	phosphorelay sensor kinase activity
MLE07_05295	COG2204	response regulator
MLE07_05300	COG0569	domain protein
MLE07_05305	COG1923	regulation of RNA biosynthetic process
MLE07_05310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MLE07_05315	COG3956	TIGRFAM MazG family protein
MLE07_05325	COG1648	precorrin-2 dehydrogenase activity
MLE07_05325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MLE07_05365	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLE07_05365	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MLE07_05370	COG0509	glycine decarboxylation via glycine cleavage system
MLE07_05375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MLE07_05400	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MLE07_05405	COG0564	pseudouridine synthase activity
MLE07_05425	COG0251	oxidation-reduction process
MLE07_05430	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MLE07_05440	COG1671	Belongs to the UPF0178 family
MLE07_05455	COG0450	alkyl hydroperoxide reductase
MLE07_05465	COG0625	glutathione transferase activity
MLE07_05500	COG0431	NADPH-dependent FMN reductase
MLE07_05510	COG0798	PFAM Bile acid sodium symporter
MLE07_05515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLE07_05530	COG0321	lipoyl(octanoyl) transferase activity
MLE07_05530	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MLE07_05535	COG0084	hydrolase, TatD family'
MLE07_05540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLE07_05550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLE07_05605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MLE07_05610	COG2095	MarC family integral membrane protein
MLE07_05615	COG0517	IMP dehydrogenase activity
MLE07_05615	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MLE07_05615	COG0617	tRNA 3'-terminal CCA addition
MLE07_05625	COG0629	single-stranded DNA binding
MLE07_05630	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MLE07_05640	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MLE07_05660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MLE07_05665	COG1121	(ABC) transporter
MLE07_05685	COG0667	Aldo Keto reductase
MLE07_05695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MLE07_05775	COG2239	Acts as a magnesium transporter
MLE07_05780	COG0243	molybdopterin cofactor binding
MLE07_05790	COG0242	peptide deformylase activity
MLE07_05805	COG2202	Pas domain
MLE07_05805	COG2205	protein histidine kinase activity
MLE07_05815	COG0321	lipoyl(octanoyl) transferase activity
MLE07_05820	COG1064	alcohol dehydrogenase
MLE07_05850	COG1862	Preprotein translocase
MLE07_05870	COG2124	cytochrome p450
MLE07_05885	COG0596	Alpha beta hydrolase
MLE07_05900	COG0626	cystathionine gamma-synthase activity
MLE07_05905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_05910	COG4597	amino acid ABC transporter
MLE07_05915	COG0765	amino acid transport
MLE07_05920	COG1126	abc transporter atp-binding protein
MLE07_05935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MLE07_05950	COG0436	Aminotransferase
MLE07_05980	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MLE07_05990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MLE07_05995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLE07_06000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MLE07_06015	COG3243	poly(R)-hydroxyalkanoic acid synthase
MLE07_06020	COG1489	DNA binding
MLE07_06025	COG0024	Methionine aminopeptidase
MLE07_06030	COG2003	Belongs to the UPF0758 family
MLE07_06045	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
MLE07_06070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MLE07_06075	COG0546	phosphoglycolate phosphatase activity
MLE07_06085	COG0114	fumarate hydratase activity
MLE07_06095	COG0504	CTP synthase activity
MLE07_06105	COG0149	triose-phosphate isomerase activity
MLE07_06115	COG0187	DNA topoisomerase II activity
MLE07_06125	COG0740	serine-type endopeptidase activity
MLE07_06135	COG0640	Transcriptional regulator
MLE07_06140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLE07_06145	COG0745	RESPONSE REGULATOR receiver
MLE07_06165	COG3264	Mechanosensitive ion channel
MLE07_06165	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MLE07_06230	COG1127	ABC transporter
MLE07_06235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MLE07_06240	COG4948	Mandelate Racemase Muconate Lactonizing
MLE07_06250	COG0280	phosphate acetyltransferase
MLE07_06250	COG0281	malic enzyme
MLE07_06260	COG0778	Nitroreductase
MLE07_06265	COG0823	Involved in the tonB-independent uptake of proteins
MLE07_06280	COG1368	sulfuric ester hydrolase activity
MLE07_06305	COG0544	peptidyl-prolyl cis-trans isomerase activity
MLE07_06325	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MLE07_06345	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MLE07_06360	COG0318	PFAM AMP-dependent synthetase and ligase
MLE07_06370	COG0512	Glutamine amidotransferase of anthranilate synthase
MLE07_06370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLE07_06375	COG0343	queuine tRNA-ribosyltransferase activity
MLE07_06380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MLE07_06395	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MLE07_06410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLE07_06415	COG0134	indole-3-glycerol-phosphate synthase activity
MLE07_06420	COG0315	cyclic pyranopterin monophosphate synthase activity
MLE07_06425	COG0303	'Molybdopterin
MLE07_06430	COG3706	GGDEF domain
MLE07_06440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MLE07_06440	COG0475	glutathione-regulated potassium exporter activity
MLE07_06450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLE07_06460	COG2814	Major facilitator Superfamily
MLE07_06465	COG0746	molybdenum cofactor guanylyltransferase activity
MLE07_06470	COG1763	Mo-molybdopterin cofactor biosynthetic process
MLE07_06475	COG0739	heme binding
MLE07_06480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MLE07_06485	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MLE07_06490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLE07_06495	COG0805	protein transport
MLE07_06500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLE07_06505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MLE07_06510	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MLE07_06515	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MLE07_06520	COG1472	Belongs to the glycosyl hydrolase 3 family
MLE07_06530	COG0018	arginyl-trna synthetase
MLE07_06535	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MLE07_06560	COG0525	valine-tRNA ligase activity
MLE07_06570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MLE07_06600	COG0655	NAD(P)H dehydrogenase (quinone) activity
MLE07_06605	COG1058	Belongs to the CinA family
MLE07_06605	COG1546	Belongs to the CinA family
MLE07_06610	COG0589	response to stress
MLE07_06615	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MLE07_06625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MLE07_06635	COG0640	Transcriptional regulator
MLE07_06640	COG1914	H( )-stimulated, divalent metal cation uptake system
MLE07_06650	COG1132	(ABC) transporter
MLE07_06655	COG0628	permease
MLE07_06690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MLE07_06700	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MLE07_06710	COG0302	gtp cyclohydrolase
MLE07_06715	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MLE07_06720	COG1752	Esterase of the alpha-beta hydrolase superfamily
MLE07_06730	COG0516	GMP reductase activity
MLE07_06730	COG0517	IMP dehydrogenase activity
MLE07_06765	COG1760	l-serine dehydratase
MLE07_06805	COG0583	DNA-binding transcription factor activity
MLE07_06820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MLE07_06820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MLE07_06830	COG0347	Belongs to the P(II) protein family
MLE07_06835	COG0174	glutamine synthetase
MLE07_06865	COG0697	spore germination
MLE07_06875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MLE07_06885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MLE07_06915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MLE07_06920	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MLE07_06925	COG2186	Transcriptional regulator
MLE07_06935	COG1079	Belongs to the binding-protein-dependent transport system permease family
MLE07_06940	COG4603	Belongs to the binding-protein-dependent transport system permease family
MLE07_06945	COG3845	ABC transporter
MLE07_06950	COG1183	phosphatidylcholine synthase activity
MLE07_06955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MLE07_06960	COG0679	Auxin Efflux Carrier
MLE07_06965	COG0785	Cytochrome C biogenesis protein
MLE07_06990	COG1278	Cold shock
MLE07_07040	COG0577	efflux transmembrane transporter activity
MLE07_07040	COG1136	(ABC) transporter
MLE07_07045	COG0577	efflux transmembrane transporter activity
MLE07_07045	COG1136	(ABC) transporter
MLE07_07070	COG2151	metal-sulfur cluster biosynthetic enzyme
MLE07_07075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MLE07_07080	COG0719	Fe-S assembly protein
MLE07_07085	COG0396	ATPase activity
MLE07_07090	COG0719	Fe-S assembly protein
MLE07_07095	COG1104	cysteine desulfurase activity
MLE07_07100	COG2945	thiolester hydrolase activity
MLE07_07105	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MLE07_07110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLE07_07120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MLE07_07125	COG2833	Protein of unknown function (DUF455)
MLE07_07130	COG0739	heme binding
MLE07_07135	COG0513	Belongs to the DEAD box helicase family
MLE07_07160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLE07_07170	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MLE07_07175	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLE07_07180	COG0047	phosphoribosylformylglycinamidine synthase activity
MLE07_07195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLE07_07200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MLE07_07220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MLE07_07225	COG2814	Major facilitator Superfamily
MLE07_07230	COG0483	inositol monophosphate 1-phosphatase activity
MLE07_07235	COG0483	inositol monophosphate 1-phosphatase activity
MLE07_07240	COG0037	tRNA processing
MLE07_07245	COG2066	Belongs to the glutaminase family
MLE07_07250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MLE07_07255	COG0861	Integral membrane protein TerC family
MLE07_07270	COG1280	lysine exporter protein (LysE YggA)
MLE07_07280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MLE07_07285	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MLE07_07295	COG0538	isocitrate dehydrogenase activity
MLE07_07305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MLE07_07310	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MLE07_07315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_07320	COG2313	pseudouridylate synthase activity
MLE07_07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_07335	COG4215	(ABC) transporter
MLE07_07345	COG5425	PFAM Usg family protein
MLE07_07355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLE07_07360	COG1522	sequence-specific DNA binding
MLE07_07365	COG1573	uracil-dna glycosylase
MLE07_07375	COG2202	Pas domain
MLE07_07375	COG2205	protein histidine kinase activity
MLE07_07385	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MLE07_07390	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MLE07_07405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MLE07_07410	COG0842	Transport permease protein
MLE07_07415	COG1131	(ABC) transporter
MLE07_07420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLE07_07420	COG0730	response to heat
MLE07_07440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MLE07_07445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MLE07_07465	COG0129	dihydroxy-acid dehydratase activity
MLE07_07470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MLE07_07475	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MLE07_07485	COG3739	integral membrane protein
MLE07_07490	COG0203	ribosomal protein L17
MLE07_07495	COG0202	RNA polymerase activity
MLE07_07500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MLE07_07505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MLE07_07510	COG0563	adenylate kinase activity
MLE07_07515	COG0201	protein transport
MLE07_07520	COG0200	Binds to the 23S rRNA
MLE07_07525	COG1841	ribosomal large subunit assembly
MLE07_07530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MLE07_07535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MLE07_07540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MLE07_07545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MLE07_07550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MLE07_07555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MLE07_07560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MLE07_07565	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MLE07_07570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MLE07_07575	COG0255	Belongs to the universal ribosomal protein uL29 family
MLE07_07580	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MLE07_07585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MLE07_07590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MLE07_07595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MLE07_07600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MLE07_07605	COG0089	rRNA binding
MLE07_07610	COG0088	Forms part of the polypeptide exit tunnel
MLE07_07615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MLE07_07620	COG0051	transcription antitermination factor activity, RNA binding
MLE07_07625	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLE07_07630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MLE07_07635	COG0049	tRNA binding
MLE07_07640	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MLE07_07655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MLE07_07660	COG0085	RNA polymerase activity
MLE07_07665	COG0222	ribosome binding
MLE07_07670	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MLE07_07675	COG0081	regulation of translation
MLE07_07680	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MLE07_07690	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MLE07_07700	COG1086	Polysaccharide biosynthesis protein
MLE07_07705	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MLE07_07710	COG0861	Integral membrane protein TerC family
MLE07_07715	COG3895	Periplasmic Protein
MLE07_07735	COG1132	(ABC) transporter
MLE07_07750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MLE07_07755	COG1607	acyl-coa hydrolase
MLE07_07775	COG2910	NAD(P)H-binding
MLE07_07780	COG1733	regulation of RNA biosynthetic process
MLE07_07795	COG0556	nucleotide-excision repair
MLE07_07800	COG2382	esterase
MLE07_07820	COG0484	heat shock protein binding
MLE07_07955	COG0328	RNA-DNA hybrid ribonuclease activity
MLE07_08025	COG3706	GGDEF domain
MLE07_08045	COG1840	ABC-type Fe3 transport system, periplasmic component
MLE07_08050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLE07_08065	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MLE07_08075	COG2207	Transcriptional regulator
MLE07_08080	COG1064	alcohol dehydrogenase
MLE07_08085	COG1252	NADH dehydrogenase
MLE07_08090	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MLE07_08095	COG2197	response regulator
MLE07_08100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MLE07_08135	COG0656	L-ascorbic acid biosynthetic process
MLE07_08150	COG0440	acetolactate synthase activity
MLE07_08155	COG0028	Belongs to the TPP enzyme family
MLE07_08170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MLE07_08175	COG0560	Phosphoserine phosphatase
MLE07_08175	COG3830	Belongs to the UPF0237 family
MLE07_08195	COG0330	HflC and HflK could
MLE07_08200	COG0330	HflC and HflK could
MLE07_08210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MLE07_08245	COG0277	FAD linked oxidase domain protein
MLE07_08250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLE07_08290	COG1335	isochorismatase
MLE07_08320	COG2264	protein methyltransferase activity
MLE07_08325	COG1999	signal sequence binding
MLE07_08335	COG0835	chemotaxis
MLE07_08345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MLE07_08350	COG0583	DNA-binding transcription factor activity
MLE07_08360	COG1247	-acetyltransferase
MLE07_08370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MLE07_08375	COG0497	DNA recombination
MLE07_08380	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MLE07_08390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLE07_08395	COG0849	cell division
MLE07_08400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MLE07_08405	COG1181	Belongs to the D-alanine--D-alanine ligase family
MLE07_08410	COG0477	Major facilitator Superfamily
MLE07_08415	COG5001	Diguanylate cyclase
MLE07_08420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MLE07_08425	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MLE07_08430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLE07_08440	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MLE07_08445	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MLE07_08455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MLE07_08470	COG0275	rRNA processing
MLE07_08475	COG2001	Belongs to the MraZ family
MLE07_08500	COG3023	N-Acetylmuramoyl-L-alanine amidase
MLE07_08530	COG4106	trans-aconitate 2-methyltransferase activity
MLE07_08550	COG2226	methyltransferase
MLE07_08560	COG2267	carboxylic ester hydrolase activity
MLE07_08565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MLE07_08580	COG0251	oxidation-reduction process
MLE07_08595	COG1376	ErfK ybiS ycfS ynhG family protein
MLE07_08625	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_08630	COG0174	glutamine synthetase
MLE07_08635	COG0531	amino acid
MLE07_08645	COG1737	Transcriptional regulator
MLE07_08650	COG2182	Extracellular solute-binding protein
MLE07_08665	COG3842	ATPase activity
MLE07_08755	COG2801	Transposase and inactivated derivatives
MLE07_08860	COG4373	Mu-like prophage FluMu protein gp28
MLE07_08985	COG1122	ATPase activity
MLE07_09005	COG2968	Membrane
MLE07_09015	COG0432	Pfam Uncharacterised protein family UPF0047
MLE07_09030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLE07_09035	COG0358	DNA primase activity
MLE07_09055	COG0505	Belongs to the CarA family
MLE07_09060	COG0534	Mate efflux family protein
MLE07_09075	COG2321	neutral zinc metallopeptidase
MLE07_09090	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MLE07_09100	COG3706	GGDEF domain
MLE07_09115	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MLE07_09125	COG1522	sequence-specific DNA binding
MLE07_09130	COG0492	ferredoxin-NADP+ reductase activity
MLE07_09135	COG0583	DNA-binding transcription factor activity
MLE07_09145	COG1902	pentaerythritol trinitrate reductase activity
MLE07_09170	COG0387	Pfam Sodium calcium exchanger
MLE07_09175	COG0436	Aminotransferase
MLE07_09180	COG2199	diguanylate cyclase activity
MLE07_09180	COG2200	EAL domain
MLE07_09195	COG1278	Cold shock
MLE07_09200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLE07_09210	COG1846	Transcriptional regulator
MLE07_09215	COG0745	RESPONSE REGULATOR receiver
MLE07_09220	COG2205	protein histidine kinase activity
MLE07_09225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLE07_09245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MLE07_09255	COG1496	oxidoreductase activity
MLE07_09270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MLE07_09280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MLE07_09295	COG0840	transmembrane signaling receptor activity
MLE07_09300	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_09305	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MLE07_09310	COG5001	Diguanylate cyclase
MLE07_09310	COG3300	MHYT domain
MLE07_09315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MLE07_09320	COG5001	Diguanylate cyclase
MLE07_09330	COG0193	aminoacyl-tRNA hydrolase activity
MLE07_09340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MLE07_09365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MLE07_09375	COG2857	Cytochrome c1
MLE07_09375	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MLE07_09395	COG1132	(ABC) transporter
MLE07_09405	COG1132	(ABC) transporter
MLE07_09415	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MLE07_09430	COG0408	coproporphyrinogen oxidase activity
MLE07_09445	COG0617	tRNA 3'-terminal CCA addition
MLE07_09460	COG0714	Associated with various cellular activities
MLE07_09480	COG0454	-acetyltransferase
MLE07_09495	COG0477	Major facilitator Superfamily
MLE07_09505	COG0435	Glutathione S-transferase
MLE07_09510	COG0494	nUDIX hydrolase
MLE07_09520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MLE07_09525	COG3135	benzoate transporter
MLE07_09550	COG0740	serine-type endopeptidase activity
MLE07_09565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MLE07_09570	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MLE07_09595	COG4175	Glycine betaine
MLE07_09615	COG1435	thymidine kinase activity
MLE07_09640	COG1629	transport
MLE07_09640	COG4771	TonB-dependent receptor
MLE07_09650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MLE07_09650	COG0512	Glutamine amidotransferase of anthranilate synthase
MLE07_09665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLE07_09675	COG0366	Alpha amylase catalytic
MLE07_09680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_09700	COG1160	GTP binding
MLE07_09720	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MLE07_09730	COG0024	Methionine aminopeptidase
MLE07_09740	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_09760	COG0583	DNA-binding transcription factor activity
MLE07_09775	COG0402	S-adenosylhomocysteine deaminase activity
MLE07_09785	COG1304	FMN binding
MLE07_09795	COG1309	transcriptional regulator
MLE07_09800	COG1686	Belongs to the peptidase S11 family
MLE07_09810	COG2351	hydroxyisourate hydrolase activity
MLE07_09815	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MLE07_09840	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MLE07_09850	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MLE07_09850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_09860	COG0513	Belongs to the DEAD box helicase family
MLE07_09870	COG2259	Doxx family
MLE07_09875	COG1376	ErfK ybiS ycfS ynhG family protein
MLE07_09885	COG2308	Evidence 4 Homologs of previously reported genes of
MLE07_09895	COG1305	Transglutaminase-like
MLE07_09915	COG0588	phosphoglycerate mutase activity
MLE07_09925	COG4214	carbohydrate transport
MLE07_09935	COG4213	ABC transporter substrate-binding protein
MLE07_09970	COG0840	transmembrane signaling receptor activity
MLE07_09985	COG1410	methionine synthase
MLE07_09985	COG0646	methionine synthase
MLE07_10030	COG1215	transferase activity, transferring glycosyl groups
MLE07_10060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLE07_10065	COG2346	COG2346, Truncated hemoglobins
MLE07_10085	COG1309	transcriptional regulator
MLE07_10100	COG0494	nUDIX hydrolase
MLE07_10110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_10115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_10145	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MLE07_10150	COG0830	nickel cation binding
MLE07_10155	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MLE07_10170	COG0804	urea catabolic process
MLE07_10175	COG1442	glycosyl transferase family 8
MLE07_10180	COG3755	Protein conserved in bacteria
MLE07_10190	COG0832	Belongs to the urease beta subunit family
MLE07_10195	COG3813	Protein conserved in bacteria
MLE07_10200	COG0831	urea catabolic process
MLE07_10205	COG0829	nickel cation binding
MLE07_10235	COG0559	Belongs to the binding-protein-dependent transport system permease family
MLE07_10250	COG0174	glutamine synthetase
MLE07_10255	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_10260	COG2198	Histidine kinase
MLE07_10260	COG0784	Response regulator, receiver
MLE07_10260	COG5002	protein histidine kinase activity
MLE07_10275	COG0726	polysaccharide deacetylase
MLE07_10310	COG1218	3'(2'),5'-bisphosphate nucleotidase
MLE07_10385	COG0564	pseudouridine synthase activity
MLE07_10395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MLE07_10405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MLE07_10430	COG0346	lactoylglutathione lyase activity
MLE07_10440	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MLE07_10450	COG2832	Protein of unknown function (DUF454)
MLE07_10455	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MLE07_10460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_10465	COG4558	Periplasmic binding protein
MLE07_10475	COG3721	Heme iron utilization protein
MLE07_10495	COG2205	protein histidine kinase activity
MLE07_10535	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_10540	COG4605	iron ion homeostasis
MLE07_10545	COG4604	ABC transporter, ATP-binding protein
MLE07_10550	COG0783	Belongs to the Dps family
MLE07_10565	COG2972	Histidine kinase
MLE07_10565	COG0840	transmembrane signaling receptor activity
MLE07_10570	COG0656	L-ascorbic acid biosynthetic process
MLE07_10575	COG2814	Major facilitator Superfamily
MLE07_10585	COG0583	DNA-binding transcription factor activity
MLE07_10590	COG0657	acetylesterase activity
MLE07_10595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_10615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MLE07_10620	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MLE07_10625	COG0288	reversible hydration of carbon dioxide
MLE07_10635	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MLE07_10655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MLE07_10660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLE07_10665	COG0778	Nitroreductase
MLE07_10670	COG2267	carboxylic ester hydrolase activity
MLE07_10675	COG0251	oxidation-reduction process
MLE07_10680	COG1335	isochorismatase
MLE07_10685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_10695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_10710	COG1175	transmembrane transport
MLE07_10715	COG0395	ABC-type sugar transport system, permease component
MLE07_10720	COG3842	ATPase activity
MLE07_10725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_10735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLE07_10750	COG4608	Belongs to the ABC transporter superfamily
MLE07_10755	COG0444	Belongs to the ABC transporter superfamily
MLE07_10760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_10765	COG0601	transmembrane transport
MLE07_10820	COG2159	amidohydrolase
MLE07_10825	COG1960	acyl-CoA dehydrogenase activity
MLE07_10855	COG0745	RESPONSE REGULATOR receiver
MLE07_10865	COG1902	pentaerythritol trinitrate reductase activity
MLE07_10865	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLE07_10870	COG3842	ATPase activity
MLE07_10880	COG1840	ABC-type Fe3 transport system, periplasmic component
MLE07_10885	COG1840	ABC-type Fe3 transport system, periplasmic component
MLE07_10890	COG0745	RESPONSE REGULATOR receiver
MLE07_10900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLE07_10905	COG0583	DNA-binding transcription factor activity
MLE07_10910	COG1278	Cold shock
MLE07_10945	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
MLE07_10945	COG3210	domain, Protein
MLE07_10945	COG3064	Membrane
MLE07_10975	COG1126	abc transporter atp-binding protein
MLE07_10985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_10990	COG1609	Transcriptional regulator
MLE07_11000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_11005	COG0477	Major facilitator Superfamily
MLE07_11010	COG0693	protein deglycase activity
MLE07_11015	COG1879	ABC-type sugar transport system periplasmic component
MLE07_11020	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_11025	COG1129	ABC transporter
MLE07_11030	COG1802	Transcriptional regulator
MLE07_11035	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MLE07_11040	COG1454	alcohol dehydrogenase
MLE07_11050	COG0657	acetylesterase activity
MLE07_11085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLE07_11100	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_11105	COG4191	Histidine kinase
MLE07_11110	COG4566	intracellular signal transduction
MLE07_11115	COG2204	response regulator
MLE07_11120	COG4566	intracellular signal transduction
MLE07_11125	COG0583	DNA-binding transcription factor activity
MLE07_11130	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_11135	COG0656	L-ascorbic acid biosynthetic process
MLE07_11140	COG0667	Aldo Keto reductase
MLE07_11210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MLE07_11215	COG1309	transcriptional regulator
MLE07_11220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_11225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLE07_11235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MLE07_11240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MLE07_11260	COG0583	DNA-binding transcription factor activity
MLE07_11265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_11270	COG0725	ABC transporter, periplasmic molybdate-binding protein
MLE07_11275	COG4149	molybdate abc transporter
MLE07_11280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MLE07_11295	COG2022	thiamine diphosphate biosynthetic process
MLE07_11310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MLE07_11315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLE07_11325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MLE07_11345	COG1132	(ABC) transporter
MLE07_11350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MLE07_11375	COG0438	transferase activity, transferring glycosyl groups
MLE07_11395	COG4166	transmembrane transport
MLE07_11400	COG0601	transmembrane transport
MLE07_11405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_11415	COG0438	transferase activity, transferring glycosyl groups
MLE07_11420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MLE07_11425	COG3142	Participates in the control of copper homeostasis
MLE07_11430	COG2814	Major facilitator Superfamily
MLE07_11445	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_11450	COG1737	Transcriptional regulator
MLE07_11460	COG3842	ATPase activity
MLE07_11470	COG0395	ABC-type sugar transport system, permease component
MLE07_11490	COG2188	Transcriptional regulator
MLE07_11495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MLE07_11500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MLE07_11505	COG1940	carbohydrate kinase activity
MLE07_11515	COG0671	phosphoesterase, PA-phosphatase related
MLE07_11520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MLE07_11525	COG0156	8-amino-7-oxononanoate synthase activity
MLE07_11535	COG0729	surface antigen
MLE07_11545	COG0835	chemotaxis
MLE07_11555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MLE07_11560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MLE07_11565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MLE07_11570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MLE07_11575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MLE07_11580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MLE07_11595	COG4974	Belongs to the 'phage' integrase family
MLE07_11620	COG1280	lysine exporter protein (LysE YggA)
MLE07_11630	COG0508	dehydrogenase complex catalyzes the overall conversion of
MLE07_11635	COG0567	Dehydrogenase, E1 component
MLE07_11640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MLE07_11645	COG0045	succinate-CoA ligase (ADP-forming) activity
MLE07_11650	COG0039	L-malate dehydrogenase activity
MLE07_11655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MLE07_11690	COG2264	protein methyltransferase activity
MLE07_11705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MLE07_11710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MLE07_11715	COG0181	hydroxymethylbilane synthase activity
MLE07_11755	COG1872	DUF167
MLE07_11760	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MLE07_11770	COG1217	gtp-binding protein TYPA
MLE07_11775	COG0339	signal peptide processing
MLE07_11780	COG1846	Transcriptional regulator
MLE07_11790	COG0137	argininosuccinate synthase activity
MLE07_11800	COG1280	lysine exporter protein (LysE YggA)
MLE07_11805	COG1122	ATPase activity
MLE07_11810	COG4120	Belongs to the binding-protein-dependent transport system permease family
MLE07_11820	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MLE07_11835	COG2154	pterin-4-alpha-carbinolamine dehydratase
MLE07_11840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MLE07_11845	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MLE07_11855	COG4181	ATPase activity
MLE07_11865	COG0670	Belongs to the BI1 family
MLE07_11880	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MLE07_11885	COG4133	protoheme IX ABC transporter activity
MLE07_11890	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MLE07_11895	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MLE07_11920	COG2917	probably involved in intracellular septation
MLE07_11925	COG0552	protein localization to endoplasmic reticulum
MLE07_11930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MLE07_11935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MLE07_11950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MLE07_11955	COG0287	Prephenate dehydrogenase
MLE07_11955	COG1605	Chorismate mutase
MLE07_11960	COG0228	four-way junction DNA binding
MLE07_11965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MLE07_11970	COG0336	Belongs to the RNA methyltransferase TrmD family
MLE07_11980	COG0335	large ribosomal subunit rRNA binding
MLE07_11985	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
MLE07_11990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_12005	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MLE07_12025	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MLE07_12045	COG0488	(ABC) transporter
MLE07_12055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MLE07_12065	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MLE07_12070	COG0142	geranyltranstransferase activity
MLE07_12075	COG2885	chlorophyll binding
MLE07_12080	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MLE07_12085	COG2223	nitrite transmembrane transporter activity
MLE07_12090	COG1349	DNA-binding transcription factor activity
MLE07_12095	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MLE07_12100	COG2197	response regulator
MLE07_12105	COG1132	(ABC) transporter
MLE07_12110	COG3459	Glycosyltransferase 36 associated
MLE07_12115	COG1473	amidohydrolase
MLE07_12125	COG0579	oxidoreductase
MLE07_12135	COG0129	dihydroxy-acid dehydratase activity
MLE07_12140	COG2084	Dehydrogenase
MLE07_12145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLE07_12150	COG0277	FAD linked oxidase domain protein
MLE07_12155	COG2186	Transcriptional regulator
MLE07_12165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MLE07_12170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MLE07_12175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MLE07_12180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MLE07_12190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MLE07_12195	COG0495	leucyl-tRNA aminoacylation
MLE07_12210	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MLE07_12215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MLE07_12230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MLE07_12235	COG1946	Acyl-CoA thioesterase
MLE07_12240	COG0347	Belongs to the P(II) protein family
MLE07_12245	COG0004	ammonium transporteR
MLE07_12250	COG1674	ftsk spoiiie
MLE07_12255	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MLE07_12270	COG0745	RESPONSE REGULATOR receiver
MLE07_12280	COG1329	Transcriptional regulator
MLE07_12290	COG2270	Major facilitator Superfamily
MLE07_12305	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_12320	COG0494	nUDIX hydrolase
MLE07_12325	COG2861	carbohydrate metabolic process
MLE07_12330	COG0793	Belongs to the peptidase S41A family
MLE07_12340	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MLE07_12345	COG0799	negative regulation of ribosome biogenesis
MLE07_12350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MLE07_12355	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MLE07_12360	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MLE07_12365	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MLE07_12380	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MLE07_12385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MLE07_12410	COG0066	3-isopropylmalate dehydratase activity
MLE07_12415	COG0473	3-isopropylmalate dehydrogenase activity
MLE07_12420	COG1858	cytochrome C peroxidase
MLE07_12425	COG1797	cobyrinic acid a,c-diamide synthase activity
MLE07_12435	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MLE07_12500	COG1492	cobalamin metabolic process
MLE07_12515	COG4948	Mandelate Racemase Muconate Lactonizing
MLE07_12520	COG3254	rhamnose metabolic process
MLE07_12525	COG0246	Mannitol dehydrogenase
MLE07_12530	COG1063	alcohol dehydrogenase
MLE07_12555	COG1129	ABC transporter
MLE07_12560	COG2186	Transcriptional regulator
MLE07_12565	COG2721	sulfolactate sulfo-lyase activity
MLE07_12570	COG0138	bifunctional purine biosynthesis protein purh
MLE07_12580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MLE07_12580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MLE07_12585	COG0501	Belongs to the peptidase M48B family
MLE07_12605	COG0357	Ribosomal RNA small subunit methyltransferase G
MLE07_12610	COG0445	tRNA wobble uridine modification
MLE07_12615	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MLE07_12620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MLE07_12625	COG1981	membrane
MLE07_12630	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MLE07_12635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MLE07_12640	COG0424	maF-like protein
MLE07_12645	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLE07_12650	COG0237	dephospho-CoA kinase activity
MLE07_12660	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MLE07_12665	COG3030	protein affecting phage T7 exclusion by the F plasmid
MLE07_12675	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MLE07_12700	COG0179	Fumarylacetoacetate (FAA) hydrolase
MLE07_12715	COG0135	phosphoribosylanthranilate isomerase activity
MLE07_12720	COG0133	tryptophan synthase activity
MLE07_12725	COG0159	tryptophan synthase activity
MLE07_12730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MLE07_12745	COG1074	ATP-dependent DNA helicase activity
MLE07_12755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MLE07_12760	COG0802	atpase or kinase
MLE07_12765	COG2205	protein histidine kinase activity
MLE07_12770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MLE07_12775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLE07_12780	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MLE07_12780	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
MLE07_12785	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MLE07_12790	COG0642	Histidine kinase
MLE07_12795	COG0745	RESPONSE REGULATOR receiver
MLE07_12800	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MLE07_12810	COG1652	LysM domain
MLE07_12815	COG1072	(Pantothenic acid kinase))
MLE07_12820	COG0140	phosphoribosyl-ATP diphosphatase activity
MLE07_12825	COG0107	imidazoleglycerol-phosphate synthase activity
MLE07_12830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MLE07_12835	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MLE07_12845	COG0131	Imidazoleglycerol-phosphate dehydratase
MLE07_12850	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MLE07_12855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MLE07_12865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MLE07_12880	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MLE07_12890	COG1643	Atp-dependent helicase
MLE07_12950	COG1072	(Pantothenic acid kinase))
MLE07_12960	COG1780	Probably involved in ribonucleotide reductase function
MLE07_12980	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MLE07_13010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_13020	COG2813	Specifically methylates the guanine in position
MLE07_13025	COG1185	polyribonucleotide nucleotidyltransferase activity
MLE07_13030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MLE07_13035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MLE07_13040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MLE07_13045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MLE07_13045	COG3064	Membrane
MLE07_13060	COG0779	Required for maturation of 30S ribosomal subunits
MLE07_13065	COG2814	Major facilitator Superfamily
MLE07_13070	COG2951	lytic endotransglycosylase activity
MLE07_13075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MLE07_13085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MLE07_13090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MLE07_13105	COG2816	NAD+ diphosphatase activity
MLE07_13110	COG0077	Prephenate dehydratase
MLE07_13110	COG1605	Chorismate mutase
MLE07_13115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MLE07_13120	COG3474	cytochrome
MLE07_13130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MLE07_13140	COG1278	Cold shock
MLE07_13145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MLE07_13155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLE07_13155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MLE07_13165	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MLE07_13195	COG2900	Belongs to the SlyX family
MLE07_13215	COG0484	heat shock protein binding
MLE07_13220	COG0443	Heat shock 70 kDa protein
MLE07_13240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MLE07_13245	COG1744	ABC transporter substrate-binding protein PnrA-like
MLE07_13250	COG3845	ABC transporter
MLE07_13255	COG1079	Belongs to the binding-protein-dependent transport system permease family
MLE07_13260	COG1079	Belongs to the binding-protein-dependent transport system permease family
MLE07_13265	COG0295	cytidine deaminase activity
MLE07_13270	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MLE07_13275	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MLE07_13280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MLE07_13290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MLE07_13295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MLE07_13300	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MLE07_13310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MLE07_13315	COG1845	cytochrome c oxidase, subunit III
MLE07_13320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLE07_13325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MLE07_13330	COG0477	Major facilitator Superfamily
MLE07_13335	COG0067	glutamate synthase
MLE07_13335	COG0069	glutamate synthase activity
MLE07_13335	COG0070	glutamate synthase
MLE07_13340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MLE07_13355	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MLE07_13365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MLE07_13395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_13415	COG0848	biopolymer transport protein
MLE07_13425	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MLE07_13440	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MLE07_13445	COG3454	Phosphonate metabolism
MLE07_13450	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
MLE07_13455	COG3639	organic phosphonate transmembrane transporter activity
MLE07_13460	COG3639	organic phosphonate transmembrane transporter activity
MLE07_13465	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MLE07_13470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MLE07_13480	COG4778	phosphonate C-P lyase system protein PhnL
MLE07_13485	COG4107	phosphonate C-P lyase system protein PhnK
MLE07_13490	COG3627	carbon phosphorus lyase activity
MLE07_13495	COG3626	phosphonate metabolism
MLE07_13500	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MLE07_13505	COG3624	Phosphonate C-P lyase system protein PhnG
MLE07_13510	COG2188	Transcriptional regulator
MLE07_13515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MLE07_13520	COG0837	glucose binding
MLE07_13525	COG1803	Methylglyoxal synthase
MLE07_13530	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
MLE07_13535	COG4166	transmembrane transport
MLE07_13540	COG4174	ABC transporter (Permease)
MLE07_13545	COG4239	(ABC) transporter, permease
MLE07_13550	COG4172	Belongs to the ABC transporter superfamily
MLE07_13555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_13560	COG0174	glutamine synthetase
MLE07_13565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_13570	COG3265	gluconokinase activity
MLE07_13575	COG1174	glycine betaine transport
MLE07_13580	COG1125	glycine betaine transport
MLE07_13585	COG1174	glycine betaine transport
MLE07_13590	COG1732	Glycine betaine
MLE07_13600	COG1959	2 iron, 2 sulfur cluster binding
MLE07_13605	COG1840	ABC-type Fe3 transport system, periplasmic component
MLE07_13615	COG4269	membrane
MLE07_13630	COG0697	spore germination
MLE07_13645	COG0791	NLP P60 protein
MLE07_13655	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MLE07_13660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MLE07_13695	COG4964	Belongs to the GSP D family
MLE07_13730	COG2963	transposase activity
MLE07_13735	COG3436	PFAM IS66 Orf2 family protein
MLE07_13740	COG4372	Transposase
MLE07_13750	COG2815	serine threonine protein kinase
MLE07_13750	COG0515	serine threonine protein kinase
MLE07_13810	COG3422	double-strand break repair
MLE07_13815	COG3757	hydrolase, family 25
MLE07_13820	COG0697	spore germination
MLE07_13825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLE07_13840	COG0492	ferredoxin-NADP+ reductase activity
MLE07_13855	COG0481	GTPase activity
MLE07_13860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MLE07_13875	COG1396	sequence-specific DNA binding
MLE07_13890	COG2169	Transcriptional regulator
MLE07_13890	COG1917	Cupin 2, conserved barrel domain protein
MLE07_13895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MLE07_13920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MLE07_13925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MLE07_13930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MLE07_13940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MLE07_13945	COG0072	phenylalanine-tRNA ligase activity
MLE07_13945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MLE07_13950	COG0667	Aldo Keto reductase
MLE07_13970	COG4977	sequence-specific DNA binding
MLE07_13995	COG1570	exodeoxyribonuclease VII activity
MLE07_14000	COG4948	Mandelate Racemase Muconate Lactonizing
MLE07_14010	COG1846	Transcriptional regulator
MLE07_14015	COG0697	spore germination
MLE07_14020	COG2309	aminopeptidase activity
MLE07_14030	COG1393	Belongs to the ArsC family
MLE07_14050	COG1309	transcriptional regulator
MLE07_14060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MLE07_14060	COG0519	Catalyzes the synthesis of GMP from XMP
MLE07_14075	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
MLE07_14105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MLE07_14115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MLE07_14125	COG1968	undecaprenyl-diphosphatase activity
MLE07_14140	COG0284	orotidine-5'-phosphate decarboxylase activity
MLE07_14150	COG3963	phosphatidate phosphatase activity
MLE07_14160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MLE07_14165	COG0792	nuclease activity
MLE07_14180	COG1175	transmembrane transport
MLE07_14185	COG0395	ABC-type sugar transport system, permease component
MLE07_14190	COG3842	ATPase activity
MLE07_14200	COG0189	ligase activity
MLE07_14205	COG0606	chelatase, subunit chli
MLE07_14210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MLE07_14215	COG1280	lysine exporter protein (LysE YggA)
MLE07_14220	COG0756	dUTP diphosphatase activity
MLE07_14225	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MLE07_14230	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MLE07_14245	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MLE07_14250	COG2226	methyltransferase
MLE07_14255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MLE07_14260	COG1024	Enoyl-CoA hydratase
MLE07_14265	COG0268	Binds directly to 16S ribosomal RNA
MLE07_14295	COG1278	Cold shock
MLE07_14380	COG1278	Cold shock
MLE07_14390	COG0604	alcohol dehydrogenase
MLE07_14395	COG1733	regulation of RNA biosynthetic process
MLE07_14415	COG1522	sequence-specific DNA binding
MLE07_14440	COG0596	Alpha beta hydrolase
MLE07_14455	COG1764	response to oxidative stress
MLE07_14465	COG0596	Alpha beta hydrolase
MLE07_14485	COG0783	Belongs to the Dps family
MLE07_14490	COG0243	molybdopterin cofactor binding
MLE07_14500	COG4566	intracellular signal transduction
MLE07_14505	COG4566	intracellular signal transduction
MLE07_14515	COG2140	Oxalate decarboxylase
MLE07_14530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MLE07_14530	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MLE07_14535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MLE07_14545	COG1414	Transcriptional regulator
MLE07_14560	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_14580	COG1522	sequence-specific DNA binding
MLE07_14600	COG0628	permease
MLE07_14610	COG2235	arginine
MLE07_14645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MLE07_14655	COG0702	epimerase
MLE07_14660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLE07_14665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_14670	COG0745	RESPONSE REGULATOR receiver
MLE07_14675	COG5002	protein histidine kinase activity
MLE07_14690	COG2233	PERMEase
MLE07_14750	COG0395	ABC-type sugar transport system, permease component
MLE07_14755	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLE07_14765	COG3842	ATPase activity
MLE07_14810	COG0395	ABC-type sugar transport system, permease component
MLE07_14815	COG3842	ATPase activity
MLE07_14830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLE07_14835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_14840	COG1116	anion transmembrane transporter activity
MLE07_14845	COG0395	ABC-type sugar transport system, permease component
MLE07_14850	COG1175	transmembrane transport
MLE07_14880	COG1609	Transcriptional regulator
MLE07_14895	COG1082	Xylose isomerase domain protein TIM barrel
MLE07_14910	COG3842	ATPase activity
MLE07_14915	COG0395	ABC-type sugar transport system, permease component
MLE07_14920	COG1175	transmembrane transport
MLE07_14925	COG1653	transport
MLE07_14930	COG1309	transcriptional regulator
MLE07_14935	COG0673	inositol 2-dehydrogenase activity
MLE07_14950	COG0673	inositol 2-dehydrogenase activity
MLE07_14960	COG1278	Cold shock
MLE07_14970	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MLE07_14995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MLE07_15000	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MLE07_15015	COG3842	ATPase activity
MLE07_15020	COG0395	ABC-type sugar transport system, permease component
MLE07_15025	COG1175	transmembrane transport
MLE07_15035	COG3618	amidohydrolase
MLE07_15040	COG4948	Mandelate Racemase Muconate Lactonizing
MLE07_15045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_15050	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_15055	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MLE07_15060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLE07_15065	COG2186	Transcriptional regulator
MLE07_15080	COG0667	Aldo Keto reductase
MLE07_15110	COG4977	sequence-specific DNA binding
MLE07_15115	COG2223	nitrite transmembrane transporter activity
MLE07_15120	COG1609	Transcriptional regulator
MLE07_15125	COG1063	alcohol dehydrogenase
MLE07_15130	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_15140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_15145	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
MLE07_15150	COG1175	transmembrane transport
MLE07_15155	COG0395	ABC-type sugar transport system, permease component
MLE07_15170	COG0395	ABC-type sugar transport system, permease component
MLE07_15175	COG1175	transmembrane transport
MLE07_15180	COG2182	Extracellular solute-binding protein
MLE07_15185	COG0626	cystathionine gamma-synthase activity
MLE07_15200	COG0454	-acetyltransferase
MLE07_15205	COG0803	Belongs to the bacterial solute-binding protein 9 family
MLE07_15215	COG1121	(ABC) transporter
MLE07_15220	COG0523	cobalamin synthesis protein
MLE07_15235	COG0523	cobalamin synthesis protein
MLE07_15240	COG1653	transport
MLE07_15245	COG1175	transmembrane transport
MLE07_15250	COG0395	ABC-type sugar transport system, permease component
MLE07_15255	COG3842	ATPase activity
MLE07_15265	COG3047	cAMP biosynthetic process
MLE07_15290	COG0583	DNA-binding transcription factor activity
MLE07_15295	COG1879	ABC-type sugar transport system periplasmic component
MLE07_15300	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_15305	COG1129	ABC transporter
MLE07_15315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MLE07_15320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_15340	COG3257	ureidoglycine aminohydrolase activity
MLE07_15350	COG5001	Diguanylate cyclase
MLE07_15355	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MLE07_15365	COG0747	negative chemotaxis
MLE07_15370	COG0601	transmembrane transport
MLE07_15375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_15380	COG0444	Belongs to the ABC transporter superfamily
MLE07_15385	COG4608	Belongs to the ABC transporter superfamily
MLE07_15390	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MLE07_15405	COG0346	lactoylglutathione lyase activity
MLE07_15415	COG0129	dihydroxy-acid dehydratase activity
MLE07_15420	COG1879	ABC-type sugar transport system periplasmic component
MLE07_15425	COG1129	ABC transporter
MLE07_15430	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_15435	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_15440	COG2186	Transcriptional regulator
MLE07_15455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MLE07_15460	COG0587	DNA-directed DNA polymerase activity
MLE07_15490	COG0673	inositol 2-dehydrogenase activity
MLE07_15500	COG3842	ATPase activity
MLE07_15505	COG0395	ABC-type sugar transport system, permease component
MLE07_15510	COG1175	transmembrane transport
MLE07_15515	COG1653	transport
MLE07_15525	COG0673	inositol 2-dehydrogenase activity
MLE07_15540	COG5001	Diguanylate cyclase
MLE07_15555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MLE07_15560	COG2894	cell division
MLE07_15565	COG0850	regulation of cytokinetic process
MLE07_15570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MLE07_15575	COG2186	Transcriptional regulator
MLE07_15580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MLE07_15590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MLE07_15595	COG1063	alcohol dehydrogenase
MLE07_15600	COG1312	Catalyzes the dehydration of D-mannonate
MLE07_15620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MLE07_15625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MLE07_15625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MLE07_15630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_15645	COG0625	glutathione transferase activity
MLE07_15655	COG1921	L-seryl-tRNASec selenium transferase activity
MLE07_15670	COG3964	amidohydrolase
MLE07_15680	COG0601	transmembrane transport
MLE07_15685	COG0747	negative chemotaxis
MLE07_15690	COG0438	transferase activity, transferring glycosyl groups
MLE07_15725	COG4989	oxidoreductase activity
MLE07_15735	COG2188	Transcriptional regulator
MLE07_15745	COG4943	cyclic-guanylate-specific phosphodiesterase activity
MLE07_15760	COG3842	ATPase activity
MLE07_15765	COG1653	transport
MLE07_15770	COG1175	transmembrane transport
MLE07_15775	COG0395	ABC-type sugar transport system, permease component
MLE07_15780	COG1501	Belongs to the glycosyl hydrolase 31 family
MLE07_15790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_15795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLE07_15800	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MLE07_15805	COG0352	thiamine-phosphate diphosphorylase activity
MLE07_15810	COG0351	phosphomethylpyrimidine kinase
MLE07_15815	COG1522	sequence-specific DNA binding
MLE07_15820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MLE07_15825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_15840	COG2204	response regulator
MLE07_15845	COG4191	Histidine kinase
MLE07_15850	COG1301	dicarboxylic acid transport
MLE07_15855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLE07_15860	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_15870	COG1473	amidohydrolase
MLE07_15890	COG1215	transferase activity, transferring glycosyl groups
MLE07_15900	COG2942	2-epimerase
MLE07_15925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLE07_15935	COG2197	response regulator
MLE07_15965	COG3307	-O-antigen
MLE07_15970	COG1596	polysaccharide export
MLE07_15975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MLE07_15985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLE07_15990	COG0840	transmembrane signaling receptor activity
MLE07_15990	COG2972	Histidine kinase
MLE07_15995	COG1376	ErfK ybiS ycfS ynhG family protein
MLE07_16005	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_16015	COG2094	Belongs to the DNA glycosylase MPG family
MLE07_16030	COG1609	Transcriptional regulator
MLE07_16035	COG1653	transport
MLE07_16050	COG3842	ATPase activity
MLE07_16060	COG0673	inositol 2-dehydrogenase activity
MLE07_16065	COG0602	queuosine metabolic process
MLE07_16070	COG0720	synthase
MLE07_16075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MLE07_16080	COG0673	inositol 2-dehydrogenase activity
MLE07_16095	COG0395	ABC-type sugar transport system, permease component
MLE07_16100	COG1175	transmembrane transport
MLE07_16125	COG0583	DNA-binding transcription factor activity
MLE07_16130	COG0281	malic enzyme
MLE07_16130	COG0280	phosphate acetyltransferase
MLE07_16145	COG0765	amino acid transport
MLE07_16150	COG1126	abc transporter atp-binding protein
MLE07_16155	COG2079	MmgE PrpD family protein
MLE07_16160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_16185	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MLE07_16195	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MLE07_16200	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MLE07_16205	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_16210	COG1129	ABC transporter
MLE07_16225	COG1473	amidohydrolase
MLE07_16230	COG0747	negative chemotaxis
MLE07_16245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_16250	COG0601	transmembrane transport
MLE07_16255	COG0583	DNA-binding transcription factor activity
MLE07_16260	COG1446	asparaginase
MLE07_16275	COG0747	negative chemotaxis
MLE07_16295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_16300	COG0601	transmembrane transport
MLE07_16305	COG2197	response regulator
MLE07_16310	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MLE07_16315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLE07_16325	COG3842	ATPase activity
MLE07_16330	COG0395	ABC-type sugar transport system, permease component
MLE07_16335	COG1175	transmembrane transport
MLE07_16345	COG0673	inositol 2-dehydrogenase activity
MLE07_16350	COG0673	inositol 2-dehydrogenase activity
MLE07_16370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_16375	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
MLE07_16395	COG1595	DNA-templated transcription, initiation
MLE07_16400	COG1120	ATPase activity
MLE07_16405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_16420	COG2226	methyltransferase
MLE07_16430	COG1120	ATPase activity
MLE07_16435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_16480	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_16485	COG0473	3-isopropylmalate dehydrogenase activity
MLE07_16490	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_16495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_16530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_16535	COG4172	Belongs to the ABC transporter superfamily
MLE07_16540	COG1522	sequence-specific DNA binding
MLE07_16550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_16565	COG0583	DNA-binding transcription factor activity
MLE07_16575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_16580	COG1126	abc transporter atp-binding protein
MLE07_16595	COG1473	amidohydrolase
MLE07_16600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16605	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16610	COG1959	2 iron, 2 sulfur cluster binding
MLE07_16620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLE07_16625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16655	COG1960	acyl-CoA dehydrogenase activity
MLE07_16665	COG0747	negative chemotaxis
MLE07_16680	COG0444	Belongs to the ABC transporter superfamily
MLE07_16690	COG0667	Aldo Keto reductase
MLE07_16700	COG0583	DNA-binding transcription factor activity
MLE07_16705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16710	COG4166	transmembrane transport
MLE07_16720	COG0747	negative chemotaxis
MLE07_16725	COG1473	amidohydrolase
MLE07_16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_16770	COG4608	Belongs to the ABC transporter superfamily
MLE07_16775	COG0444	Belongs to the ABC transporter superfamily
MLE07_16785	COG0601	transmembrane transport
MLE07_16795	COG2186	Transcriptional regulator
MLE07_16810	COG0300	oxidoreductase activity
MLE07_16820	COG3453	Protein conserved in bacteria
MLE07_16820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLE07_16825	COG0640	Transcriptional regulator
MLE07_16835	COG2391	methyltransferase activity
MLE07_16840	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MLE07_16850	COG0022	dehydrogenase e1 component
MLE07_16860	COG1960	acyl-CoA dehydrogenase activity
MLE07_16865	COG0183	Belongs to the thiolase family
MLE07_16875	COG1960	acyl-CoA dehydrogenase activity
MLE07_16880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MLE07_16900	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MLE07_16905	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MLE07_16910	COG4952	isomerase
MLE07_16915	COG3347	Dehydrogenase
MLE07_16915	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_16920	COG1349	DNA-binding transcription factor activity
MLE07_16930	COG1129	ABC transporter
MLE07_16935	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_16940	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_16945	COG3254	rhamnose metabolic process
MLE07_16960	COG2264	protein methyltransferase activity
MLE07_16965	COG5001	Diguanylate cyclase
MLE07_16980	COG4335	DNA alkylation repair
MLE07_16985	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MLE07_16990	COG4208	sulfate ABC transporter
MLE07_17000	COG4150	thiosulfate binding
MLE07_17005	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MLE07_17020	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MLE07_17030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MLE07_17040	COG1040	competence protein
MLE07_17045	COG2226	methyltransferase
MLE07_17060	COG0494	nUDIX hydrolase
MLE07_17070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MLE07_17075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MLE07_17080	COG0653	protein targeting
MLE07_17085	COG0697	spore germination
MLE07_17135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MLE07_17155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MLE07_17200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_17200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MLE07_17220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
MLE07_17225	COG2086	electron transfer activity
MLE07_17230	COG0477	Major facilitator Superfamily
MLE07_17235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MLE07_17255	COG2963	transposase activity
MLE07_17260	COG3436	PFAM IS66 Orf2 family protein
MLE07_17265	COG4372	Transposase
MLE07_17280	COG0840	transmembrane signaling receptor activity
MLE07_17305	COG1840	ABC-type Fe3 transport system, periplasmic component
MLE07_17310	COG1177	transmembrane transport
MLE07_17315	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLE07_17320	COG3842	ATPase activity
MLE07_17325	COG1335	isochorismatase
MLE07_17330	COG2309	aminopeptidase activity
MLE07_17335	COG0596	Alpha beta hydrolase
MLE07_17340	COG3473	Maleate cis-trans isomerase
MLE07_17350	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_17390	COG2259	Doxx family
MLE07_17405	COG0583	DNA-binding transcription factor activity
MLE07_17410	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MLE07_17425	COG0583	DNA-binding transcription factor activity
MLE07_17430	COG2514	catechol 2,3-dioxygenase activity
MLE07_17450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLE07_17460	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MLE07_17460	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLE07_17465	COG4311	Sarcosine oxidase, delta subunit
MLE07_17470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_17475	COG4977	sequence-specific DNA binding
MLE07_17485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MLE07_17490	COG2218	PFAM glutamate synthase alpha subunit domain protein
MLE07_17495	COG0069	glutamate synthase activity
MLE07_17500	COG0174	glutamine synthetase
MLE07_17520	COG0531	amino acid
MLE07_17550	COG2353	YceI-like domain
MLE07_17565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MLE07_17580	COG3842	ATPase activity
MLE07_17585	COG0395	ABC-type sugar transport system, permease component
MLE07_17590	COG1175	transmembrane transport
MLE07_17600	COG1472	Belongs to the glycosyl hydrolase 3 family
MLE07_17705	COG2856	Zn peptidase
MLE07_17765	COG2244	polysaccharide biosynthetic process
MLE07_17780	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MLE07_17790	COG0489	protein tyrosine kinase activity
MLE07_17790	COG3206	protein involved in exopolysaccharide biosynthesis
MLE07_17810	COG0438	transferase activity, transferring glycosyl groups
MLE07_17815	COG0438	transferase activity, transferring glycosyl groups
MLE07_17830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MLE07_17835	COG2273	Hydrolase Family 16
MLE07_17835	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
MLE07_17850	COG3842	ATPase activity
MLE07_17855	COG3833	ABC-type maltose transport systems, permease component
MLE07_17910	COG1396	sequence-specific DNA binding
MLE07_17920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MLE07_17925	COG1129	ABC transporter
MLE07_17930	COG4214	carbohydrate transport
MLE07_17935	COG4213	ABC transporter substrate-binding protein
MLE07_17950	COG0346	lactoylglutathione lyase activity
MLE07_17955	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MLE07_17955	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MLE07_17960	COG4770	biotin carboxylase activity
MLE07_17975	COG0625	glutathione transferase activity
MLE07_17980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MLE07_17985	COG1396	sequence-specific DNA binding
MLE07_17985	COG3800	Transcriptional regulator
MLE07_17995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLE07_18005	COG0300	oxidoreductase activity
MLE07_18015	COG2096	Adenosyltransferase
MLE07_18025	COG2086	electron transfer activity
MLE07_18035	COG1250	3-hydroxyacyl-CoA dehydrogenase
MLE07_18045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MLE07_18050	COG0165	Argininosuccinate lyase
MLE07_18085	COG2884	Cell division ATP-binding protein ftsE
MLE07_18105	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MLE07_18115	COG0287	Prephenate dehydrogenase
MLE07_18120	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLE07_18125	COG2226	methyltransferase
MLE07_18130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MLE07_18150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MLE07_18155	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MLE07_18195	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MLE07_18200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MLE07_18210	COG4974	Belongs to the 'phage' integrase family
MLE07_18215	COG0825	malonyl-CoA metabolic process
MLE07_18220	COG3034	peptidoglycan biosynthetic process
MLE07_18225	COG0425	Belongs to the sulfur carrier protein TusA family
MLE07_18225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MLE07_18230	COG0523	cobalamin synthesis protein
MLE07_18235	COG1686	Belongs to the peptidase S11 family
MLE07_18240	COG1473	amidohydrolase
MLE07_18250	COG4953	penicillin-binding protein 1C
MLE07_18255	COG2373	Large extracellular alpha-helical protein
MLE07_18260	COG2835	tetraacyldisaccharide 4'-kinase activity
MLE07_18290	COG0482	sulfurtransferase activity
MLE07_18305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MLE07_18320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MLE07_18325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MLE07_18330	COG0037	tRNA processing
MLE07_18340	COG2885	chlorophyll binding
MLE07_18345	COG0823	Involved in the tonB-independent uptake of proteins
MLE07_18365	COG0824	Thioesterase
MLE07_18375	COG0494	nUDIX hydrolase
MLE07_18390	COG2255	four-way junction helicase activity
MLE07_18395	COG0632	four-way junction helicase activity
MLE07_18400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MLE07_18405	COG0840	transmembrane signaling receptor activity
MLE07_18410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_18415	COG0217	transcriptional regulatory protein
MLE07_18430	COG1692	metallophosphoesterase
MLE07_18440	COG1253	flavin adenine dinucleotide binding
MLE07_18475	COG3263	regulation of cellular component size
MLE07_18480	COG0126	phosphoglycerate kinase activity
MLE07_18485	COG3588	fructose-bisphosphate aldolase
MLE07_18510	COG0254	rRNA binding
MLE07_18515	COG1132	(ABC) transporter
MLE07_18540	COG0483	inositol monophosphate 1-phosphatase activity
MLE07_18570	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MLE07_18575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MLE07_18580	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MLE07_18585	COG0457	Tetratricopeptide repeat
MLE07_18595	COG3750	Belongs to the UPF0335 family
MLE07_18615	COG0469	pyruvate kinase activity
MLE07_18620	COG3108	Peptidase M15
MLE07_18625	COG2204	response regulator
MLE07_18630	COG1164	Oligoendopeptidase f
MLE07_18635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MLE07_18645	COG5310	Homospermidine synthase
MLE07_18655	COG0737	Belongs to the 5'-nucleotidase family
MLE07_18660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MLE07_18665	COG0330	HflC and HflK could
MLE07_18695	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MLE07_18700	COG2951	lytic endotransglycosylase activity
MLE07_18710	COG0745	RESPONSE REGULATOR receiver
MLE07_18715	COG2205	protein histidine kinase activity
MLE07_18730	COG0067	glutamate synthase
MLE07_18730	COG0070	glutamate synthase
MLE07_18730	COG0069	glutamate synthase activity
MLE07_18745	COG2205	protein histidine kinase activity
MLE07_18750	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MLE07_18755	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MLE07_18765	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MLE07_18775	COG0252	asparaginase activity
MLE07_18785	COG1027	Aspartate ammonia-lyase
MLE07_18790	COG2186	Transcriptional regulator
MLE07_18810	COG1309	transcriptional regulator
MLE07_18830	COG4176	ABC-type proline glycine betaine transport system permease component
MLE07_18835	COG0517	IMP dehydrogenase activity
MLE07_18835	COG4175	Glycine betaine
MLE07_18840	COG2986	histidine ammonia-lyase
MLE07_18845	COG1609	Transcriptional regulator
MLE07_18865	COG1082	Xylose isomerase domain protein TIM barrel
MLE07_18870	COG0673	inositol 2-dehydrogenase activity
MLE07_18875	COG1082	Xylose isomerase domain protein TIM barrel
MLE07_18880	COG1082	Xylose isomerase domain protein TIM barrel
MLE07_18920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MLE07_18940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_18945	COG4172	Belongs to the ABC transporter superfamily
MLE07_18950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_18955	COG0601	transmembrane transport
MLE07_18960	COG0747	negative chemotaxis
MLE07_18970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MLE07_18975	COG1454	alcohol dehydrogenase
MLE07_19015	COG2307	Protein conserved in bacteria
MLE07_19015	COG2308	Evidence 4 Homologs of previously reported genes of
MLE07_19030	COG0488	(ABC) transporter
MLE07_19035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLE07_19040	COG2186	Transcriptional regulator
MLE07_19055	COG1175	transmembrane transport
MLE07_19060	COG0395	ABC-type sugar transport system, permease component
MLE07_19070	COG3842	ATPase activity
MLE07_19095	COG1304	FMN binding
MLE07_19110	COG1063	alcohol dehydrogenase
MLE07_19115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MLE07_19120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_19130	COG0765	amino acid transport
MLE07_19135	COG0765	amino acid transport
MLE07_19140	COG4221	oxidoreductase activity
MLE07_19145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLE07_19150	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_19155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLE07_19170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MLE07_19185	COG0697	spore germination
MLE07_19190	COG0697	spore germination
MLE07_19195	COG0511	ligase activity, forming carbon-carbon bonds
MLE07_19200	COG0439	Biotin carboxylase
MLE07_19210	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MLE07_19215	COG1984	allophanate hydrolase subunit 2
MLE07_19220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MLE07_19225	COG3842	ATPase activity
MLE07_19235	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MLE07_19245	COG0436	Aminotransferase
MLE07_19260	COG0840	transmembrane signaling receptor activity
MLE07_19265	COG1070	Carbohydrate kinase
MLE07_19270	COG1830	Aldolase
MLE07_19275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLE07_19280	COG0667	Aldo Keto reductase
MLE07_19290	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_19295	COG1129	ABC transporter
MLE07_19300	COG1879	ABC-type sugar transport system periplasmic component
MLE07_19335	COG0071	Belongs to the small heat shock protein (HSP20) family
MLE07_19350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLE07_19365	COG0395	ABC-type sugar transport system, permease component
MLE07_19380	COG3842	ATPase activity
MLE07_19395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MLE07_19395	COG1648	precorrin-2 dehydrogenase activity
MLE07_19400	COG0243	molybdopterin cofactor binding
MLE07_19410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MLE07_19415	COG1116	anion transmembrane transporter activity
MLE07_19420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_19425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLE07_19435	COG3707	response regulator
MLE07_19440	COG1802	Transcriptional regulator
MLE07_19445	COG1914	H( )-stimulated, divalent metal cation uptake system
MLE07_19450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
MLE07_19455	COG4336	lyase activity
MLE07_19460	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MLE07_19465	COG4770	biotin carboxylase activity
MLE07_19470	COG0366	Alpha amylase catalytic
MLE07_19480	COG4771	TonB-dependent receptor
MLE07_19485	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MLE07_19505	COG1414	Transcriptional regulator
MLE07_19510	COG1475	DNA binding
MLE07_19515	COG1192	Involved in chromosome partitioning
MLE07_19545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLE07_19555	COG2986	histidine ammonia-lyase
MLE07_19560	COG1228	amidohydrolase
MLE07_19565	COG0402	S-adenosylhomocysteine deaminase activity
MLE07_19640	COG0596	Alpha beta hydrolase
MLE07_19665	COG0405	Gamma-glutamyltransferase
MLE07_19675	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MLE07_19680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_19685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_19695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_19700	COG0747	negative chemotaxis
MLE07_19705	COG0747	negative chemotaxis
MLE07_19715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_19725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_19735	COG1129	ABC transporter
MLE07_19740	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_19745	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_19770	COG0667	Aldo Keto reductase
MLE07_19785	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_19790	COG1129	ABC transporter
MLE07_19795	COG4213	ABC transporter substrate-binding protein
MLE07_19815	COG4608	Belongs to the ABC transporter superfamily
MLE07_19820	COG0444	Belongs to the ABC transporter superfamily
MLE07_19825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_19830	COG0601	transmembrane transport
MLE07_19835	COG0747	negative chemotaxis
MLE07_19860	COG0765	amino acid transport
MLE07_19865	COG4597	amino acid ABC transporter
MLE07_19870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_19960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_19965	COG1136	(ABC) transporter
MLE07_19965	COG0577	efflux transmembrane transporter activity
MLE07_19980	COG1846	Transcriptional regulator
MLE07_20000	COG0667	Aldo Keto reductase
MLE07_20005	COG0604	alcohol dehydrogenase
MLE07_20015	COG1309	transcriptional regulator
MLE07_20030	COG0667	Aldo Keto reductase
MLE07_20035	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_20050	COG0662	Cupin 2, conserved barrel domain protein
MLE07_20050	COG2207	Transcriptional regulator
MLE07_20055	COG4172	Belongs to the ABC transporter superfamily
MLE07_20060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_20065	COG0601	transmembrane transport
MLE07_20070	COG4166	transmembrane transport
MLE07_20075	COG0395	ABC-type sugar transport system, permease component
MLE07_20095	COG1566	PFAM secretion protein HlyD family protein
MLE07_20110	COG2207	Transcriptional regulator
MLE07_20115	COG1309	transcriptional regulator
MLE07_20120	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_20145	COG1846	Transcriptional regulator
MLE07_20150	COG0583	DNA-binding transcription factor activity
MLE07_20155	COG2828	Protein conserved in bacteria
MLE07_20170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_20185	COG0840	transmembrane signaling receptor activity
MLE07_20205	COG1215	transferase activity, transferring glycosyl groups
MLE07_20220	COG0583	DNA-binding transcription factor activity
MLE07_20225	COG0346	lactoylglutathione lyase activity
MLE07_20240	COG1574	metal-dependent hydrolase with the TIM-barrel fold
MLE07_20260	COG0583	DNA-binding transcription factor activity
MLE07_20265	COG0477	Major facilitator Superfamily
MLE07_20275	COG2205	protein histidine kinase activity
MLE07_20280	COG0745	RESPONSE REGULATOR receiver
MLE07_20285	COG0671	phosphoesterase, PA-phosphatase related
MLE07_20335	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MLE07_20345	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MLE07_20350	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLE07_20355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MLE07_20370	COG0010	Belongs to the arginase family
MLE07_20380	COG0697	spore germination
MLE07_20385	COG0673	inositol 2-dehydrogenase activity
MLE07_20405	COG0477	Major facilitator Superfamily
MLE07_20420	COG2194	sulfuric ester hydrolase activity
MLE07_20430	COG0583	DNA-binding transcription factor activity
MLE07_20435	COG4774	siderophore transport
MLE07_20450	COG1120	ATPase activity
MLE07_20460	COG3474	cytochrome
MLE07_20465	COG2137	regulation of response to DNA damage stimulus
MLE07_20470	COG3386	PFAM SMP-30 Gluconolaconase
MLE07_20480	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_20485	COG1129	ABC transporter
MLE07_20490	COG1879	ABC-type sugar transport system periplasmic component
MLE07_20495	COG4585	Histidine kinase
MLE07_20500	COG2197	response regulator
MLE07_20510	COG2133	pyrroloquinoline quinone binding
MLE07_20520	COG0500	methyltransferase
MLE07_20525	COG0564	pseudouridine synthase activity
MLE07_20540	COG3448	diguanylate cyclase activity
MLE07_20540	COG4175	Glycine betaine
MLE07_20545	COG4176	ABC-type proline glycine betaine transport system permease component
MLE07_20560	COG0784	Response regulator, receiver
MLE07_20560	COG4191	Histidine kinase
MLE07_20565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MLE07_20570	COG3206	protein involved in exopolysaccharide biosynthesis
MLE07_20570	COG0489	protein tyrosine kinase activity
MLE07_20575	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MLE07_20580	COG1215	transferase activity, transferring glycosyl groups
MLE07_20585	COG1215	transferase activity, transferring glycosyl groups
MLE07_20590	COG1215	transferase activity, transferring glycosyl groups
MLE07_20595	COG0438	transferase activity, transferring glycosyl groups
MLE07_20600	COG2273	Hydrolase Family 16
MLE07_20605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MLE07_20610	COG2244	polysaccharide biosynthetic process
MLE07_20615	COG0463	Glycosyl transferase, family 2
MLE07_20620	COG2327	Polysaccharide pyruvyl transferase
MLE07_20625	COG1215	transferase activity, transferring glycosyl groups
MLE07_20645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MLE07_20650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_20665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MLE07_20665	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLE07_20695	COG1523	belongs to the glycosyl hydrolase 13 family
MLE07_20700	COG0033	Phosphoglucomutase
MLE07_20705	COG0297	glycogen (starch) synthase activity
MLE07_20710	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MLE07_20715	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MLE07_20720	COG0058	SHG alpha-glucan phosphorylase activity
MLE07_20735	COG1794	racemase activity, acting on amino acids and derivatives
MLE07_20740	COG1522	sequence-specific DNA binding
MLE07_20750	COG2084	Dehydrogenase
MLE07_20755	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_20760	COG1063	alcohol dehydrogenase
MLE07_20770	COG4988	ABC transporter
MLE07_20775	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MLE07_20785	COG1294	oxidase, subunit
MLE07_20815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MLE07_20820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MLE07_20850	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MLE07_20855	COG0539	negative regulation of cytoplasmic translation
MLE07_20885	COG4221	oxidoreductase activity
MLE07_20895	COG0747	negative chemotaxis
MLE07_20900	COG0601	transmembrane transport
MLE07_20905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_20910	COG0444	Belongs to the ABC transporter superfamily
MLE07_20915	COG4608	Belongs to the ABC transporter superfamily
MLE07_20920	COG0246	Mannitol dehydrogenase
MLE07_20935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_20980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MLE07_20985	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_21000	COG4993	Dehydrogenase
MLE07_21005	COG3685	Protein conserved in bacteria
MLE07_21035	COG0693	protein deglycase activity
MLE07_21055	COG0189	ligase activity
MLE07_21060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MLE07_21065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MLE07_21080	COG0435	Glutathione S-transferase
MLE07_21085	COG0583	DNA-binding transcription factor activity
MLE07_21090	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_21095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MLE07_21100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MLE07_21105	COG1116	anion transmembrane transporter activity
MLE07_21115	COG1522	sequence-specific DNA binding
MLE07_21130	COG0784	Response regulator, receiver
MLE07_21140	COG3920	Histidine kinase
MLE07_21150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MLE07_21165	COG0019	diaminopimelate decarboxylase activity
MLE07_21180	COG0527	aspartate kinase activity
MLE07_21190	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MLE07_21195	COG2890	protein-(glutamine-N5) methyltransferase activity
MLE07_21205	COG0542	response to heat
MLE07_21210	COG1196	nuclear chromosome segregation
MLE07_21210	COG0741	lytic transglycosylase activity
MLE07_21210	COG0739	heme binding
MLE07_21255	COG2831	hemolysin activation secretion protein
MLE07_21260	COG3210	domain, Protein
MLE07_21285	COG2376	Dihydroxyacetone kinase
MLE07_21290	COG1522	sequence-specific DNA binding
MLE07_21310	COG0431	NADPH-dependent FMN reductase
MLE07_21320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_21330	COG4172	Belongs to the ABC transporter superfamily
MLE07_21335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_21355	COG0277	FAD linked oxidase domain protein
MLE07_21375	COG0778	Nitroreductase
MLE07_21405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLE07_21430	COG2318	DinB family
MLE07_21435	COG0583	DNA-binding transcription factor activity
MLE07_21450	COG1335	isochorismatase
MLE07_21475	COG3842	ATPase activity
MLE07_21480	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLE07_21485	COG1177	transmembrane transport
MLE07_21490	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MLE07_21500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MLE07_21515	COG1120	ATPase activity
MLE07_21520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_21525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_21530	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MLE07_21535	COG1629	transport
MLE07_21535	COG4774	siderophore transport
MLE07_21540	COG4702	Belongs to the UPF0303 family
MLE07_21560	COG1024	Enoyl-CoA hydratase
MLE07_21565	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_21570	COG1653	transport
MLE07_21575	COG1175	transmembrane transport
MLE07_21580	COG0395	ABC-type sugar transport system, permease component
MLE07_21585	COG3842	ATPase activity
MLE07_21610	COG3474	cytochrome
MLE07_21615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MLE07_21620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MLE07_21625	COG1845	cytochrome c oxidase, subunit III
MLE07_21640	COG0047	phosphoribosylformylglycinamidine synthase activity
MLE07_21655	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLE07_21655	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MLE07_21665	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLE07_21685	COG1309	transcriptional regulator
MLE07_21700	COG1136	(ABC) transporter
MLE07_21715	COG1063	alcohol dehydrogenase
MLE07_21725	COG1879	ABC-type sugar transport system periplasmic component
MLE07_21735	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_21755	COG0477	Major facilitator Superfamily
MLE07_21895	COG5001	Diguanylate cyclase
MLE07_21895	COG3300	MHYT domain
MLE07_21920	COG1253	flavin adenine dinucleotide binding
MLE07_21935	COG3842	ATPase activity
MLE07_21940	COG0395	ABC-type sugar transport system, permease component
MLE07_21945	COG1175	transmembrane transport
MLE07_21950	COG1653	transport
MLE07_21960	COG0673	inositol 2-dehydrogenase activity
MLE07_21965	COG1609	Transcriptional regulator
MLE07_21980	COG0583	DNA-binding transcription factor activity
MLE07_21990	COG1879	ABC-type sugar transport system periplasmic component
MLE07_21995	COG1129	ABC transporter
MLE07_22000	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_22005	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_22010	COG1609	Transcriptional regulator
MLE07_22020	COG0673	inositol 2-dehydrogenase activity
MLE07_22080	COG0714	Associated with various cellular activities
MLE07_22085	COG3256	nitric oxide reductase
MLE07_22100	COG1845	cytochrome c oxidase, subunit III
MLE07_22115	COG0163	prenyltransferase activity
MLE07_22120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MLE07_22125	COG3189	MarR family transcriptional regulator
MLE07_22135	COG0826	peptidase U32
MLE07_22160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MLE07_22170	COG4459	periplasmic nitrate reductase
MLE07_22185	COG0243	molybdopterin cofactor binding
MLE07_22195	COG3005	denitrification pathway
MLE07_22210	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_22215	COG1535	isochorismatase
MLE07_22215	COG3433	isochorismatase activity
MLE07_22220	COG1021	2,3-dihydroxybenzoate-AMP ligase
MLE07_22225	COG1169	isochorismate synthase
MLE07_22235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MLE07_22235	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MLE07_22240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MLE07_22250	COG2375	cellular response to nickel ion
MLE07_22260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_22265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_22270	COG1120	ATPase activity
MLE07_22275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MLE07_22285	COG4774	siderophore transport
MLE07_22285	COG1629	transport
MLE07_22290	COG1960	acyl-CoA dehydrogenase activity
MLE07_22295	COG0583	DNA-binding transcription factor activity
MLE07_22300	COG1609	Transcriptional regulator
MLE07_22310	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLE07_22320	COG3842	ATPase activity
MLE07_22330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MLE07_22335	COG0583	DNA-binding transcription factor activity
MLE07_22340	COG2814	Major facilitator Superfamily
MLE07_22345	COG1473	amidohydrolase
MLE07_22350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MLE07_22360	COG0747	negative chemotaxis
MLE07_22365	COG0601	transmembrane transport
MLE07_22370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_22375	COG0444	Belongs to the ABC transporter superfamily
MLE07_22380	COG4608	Belongs to the ABC transporter superfamily
MLE07_22385	COG0583	DNA-binding transcription factor activity
MLE07_22390	COG0747	negative chemotaxis
MLE07_22400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_22405	COG0154	amidase activity
MLE07_22410	COG0693	protein deglycase activity
MLE07_22420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_22425	COG0601	transmembrane transport
MLE07_22440	COG1473	amidohydrolase
MLE07_22445	COG4172	Belongs to the ABC transporter superfamily
MLE07_22450	COG2390	Transcriptional regulator
MLE07_22460	COG1175	transmembrane transport
MLE07_22465	COG0395	ABC-type sugar transport system, permease component
MLE07_22490	COG1069	ribulokinase activity
MLE07_22515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MLE07_22535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MLE07_22540	COG1414	Transcriptional regulator
MLE07_22545	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_22555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MLE07_22560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MLE07_22565	COG1121	(ABC) transporter
MLE07_22570	COG0803	Belongs to the bacterial solute-binding protein 9 family
MLE07_22580	COG1752	Esterase of the alpha-beta hydrolase superfamily
MLE07_22585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MLE07_22590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MLE07_22595	COG0471	metal ion transport
MLE07_22595	COG3273	potassium ion transport
MLE07_22600	COG2827	Endonuclease containing a URI domain
MLE07_22605	COG1253	flavin adenine dinucleotide binding
MLE07_22610	COG1309	transcriptional regulator
MLE07_22630	COG1609	Transcriptional regulator
MLE07_22635	COG1070	Carbohydrate kinase
MLE07_22640	COG2115	Belongs to the xylose isomerase family
MLE07_22650	COG0778	Nitroreductase
MLE07_22655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MLE07_22660	COG2011	ABC-type metal ion transport system permease component
MLE07_22670	COG5001	Diguanylate cyclase
MLE07_22670	COG3300	MHYT domain
MLE07_22675	COG1054	Belongs to the UPF0176 family
MLE07_22685	COG2954	triphosphatase activity
MLE07_22690	COG0800	Aldolase
MLE07_22710	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
MLE07_22750	COG0523	cobalamin synthesis protein
MLE07_22760	COG1846	Transcriptional regulator
MLE07_22765	COG1609	Transcriptional regulator
MLE07_22770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLE07_22780	COG3718	enzyme involved in inositol metabolism
MLE07_22790	COG3962	Belongs to the TPP enzyme family
MLE07_22795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_22810	COG0411	ABC transporter
MLE07_22825	COG0683	leucine binding
MLE07_22840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_22850	COG0747	negative chemotaxis
MLE07_22880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MLE07_22885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MLE07_22890	COG1126	abc transporter atp-binding protein
MLE07_22895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_22900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_22905	COG0765	amino acid transport
MLE07_22910	COG0765	amino acid transport
MLE07_22915	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MLE07_22920	COG3485	protocatechuate 3,4-dioxygenase
MLE07_22925	COG3485	protocatechuate 3,4-dioxygenase
MLE07_22930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MLE07_22935	COG2267	carboxylic ester hydrolase activity
MLE07_22940	COG0583	DNA-binding transcription factor activity
MLE07_22955	COG1414	Transcriptional regulator
MLE07_22965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MLE07_22970	COG0183	Belongs to the thiolase family
MLE07_22975	COG1609	Transcriptional regulator
MLE07_22990	COG1082	Xylose isomerase domain protein TIM barrel
MLE07_22995	COG0673	inositol 2-dehydrogenase activity
MLE07_23005	COG1609	Transcriptional regulator
MLE07_23010	COG0395	ABC-type sugar transport system, permease component
MLE07_23015	COG1175	transmembrane transport
MLE07_23020	COG3842	ATPase activity
MLE07_23030	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
MLE07_23050	COG2814	Major facilitator Superfamily
MLE07_23055	COG4774	siderophore transport
MLE07_23060	COG3712	iron ion homeostasis
MLE07_23070	COG1940	carbohydrate kinase activity
MLE07_23075	COG0584	glycerophosphoryl diester phosphodiesterase
MLE07_23080	COG0300	oxidoreductase activity
MLE07_23115	COG0667	Aldo Keto reductase
MLE07_23120	COG0583	DNA-binding transcription factor activity
MLE07_23130	COG1132	(ABC) transporter
MLE07_23150	COG2264	protein methyltransferase activity
MLE07_23155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MLE07_23170	COG0463	Glycosyl transferase, family 2
MLE07_23190	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MLE07_23200	COG4106	trans-aconitate 2-methyltransferase activity
MLE07_23205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MLE07_23210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MLE07_23220	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MLE07_23225	COG1091	dTDP-4-dehydrorhamnose reductase activity
MLE07_23230	COG1088	dTDP-glucose 4,6-dehydratase activity
MLE07_23235	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
MLE07_23250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_23255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_23260	COG1120	ATPase activity
MLE07_23265	COG4774	siderophore transport
MLE07_23270	COG0210	DNA helicase
MLE07_23280	COG1609	Transcriptional regulator
MLE07_23285	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLE07_23285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MLE07_23300	COG0395	ABC-type sugar transport system, permease component
MLE07_23305	COG3842	ATPase activity
MLE07_23315	COG0444	Belongs to the ABC transporter superfamily
MLE07_23320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_23325	COG0601	transmembrane transport
MLE07_23330	COG2186	Transcriptional regulator
MLE07_23350	COG3300	MHYT domain
MLE07_23350	COG5001	Diguanylate cyclase
MLE07_23355	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_23365	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLE07_23375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MLE07_23380	COG0306	phosphate transporter
MLE07_23385	COG1392	Phosphate transport regulator
MLE07_23400	COG1566	PFAM secretion protein HlyD family protein
MLE07_23405	COG0745	RESPONSE REGULATOR receiver
MLE07_23410	COG2205	protein histidine kinase activity
MLE07_23425	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
MLE07_23440	COG4774	siderophore transport
MLE07_23450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_23455	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MLE07_23460	COG1120	ATPase activity
MLE07_23465	COG0583	DNA-binding transcription factor activity
MLE07_23475	COG3119	arylsulfatase activity
MLE07_23480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MLE07_23485	COG3842	ATPase activity
MLE07_23490	COG0165	Argininosuccinate lyase
MLE07_23495	COG0395	ABC-type sugar transport system, permease component
MLE07_23500	COG1175	transmembrane transport
MLE07_23505	COG2182	Extracellular solute-binding protein
MLE07_23510	COG1940	carbohydrate kinase activity
MLE07_23535	COG1486	melibiose metabolic process
MLE07_23540	COG0747	negative chemotaxis
MLE07_23545	COG0601	transmembrane transport
MLE07_23550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_23555	COG4172	Belongs to the ABC transporter superfamily
MLE07_23560	COG1486	melibiose metabolic process
MLE07_23565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MLE07_23570	COG1129	ABC transporter
MLE07_23570	COG0842	Transport permease protein
MLE07_23575	COG0842	Transport permease protein
MLE07_23590	COG0784	Response regulator, receiver
MLE07_23595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MLE07_23605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_23610	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MLE07_23625	COG0765	amino acid transport
MLE07_23635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_23645	COG3938	Belongs to the proline racemase family
MLE07_23660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_23665	COG0765	amino acid transport
MLE07_23670	COG0765	amino acid transport
MLE07_23680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MLE07_23695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MLE07_23715	COG3383	formate dehydrogenase (NAD+) activity
MLE07_23725	COG2223	nitrite transmembrane transporter activity
MLE07_23730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_23740	COG2186	Transcriptional regulator
MLE07_23745	COG0747	negative chemotaxis
MLE07_23750	COG0601	transmembrane transport
MLE07_23755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_23760	COG4172	Belongs to the ABC transporter superfamily
MLE07_23765	COG4948	Mandelate Racemase Muconate Lactonizing
MLE07_23775	COG2186	Transcriptional regulator
MLE07_23780	COG0747	negative chemotaxis
MLE07_23785	COG0601	transmembrane transport
MLE07_23790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MLE07_23795	COG0405	Gamma-glutamyltransferase
MLE07_23805	COG0483	inositol monophosphate 1-phosphatase activity
MLE07_23815	COG3842	ATPase activity
MLE07_23820	COG0395	ABC-type sugar transport system, permease component
MLE07_23840	COG3237	CsbD-like
MLE07_23850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MLE07_23855	COG3181	Tripartite tricarboxylate transporter family receptor
MLE07_23860	COG5265	(ABC) transporter
MLE07_23865	COG0488	(ABC) transporter
MLE07_23890	COG1049	propionate catabolic process, 2-methylcitrate cycle
MLE07_23895	COG0110	maltose O-acetyltransferase activity
MLE07_23905	COG1063	alcohol dehydrogenase
MLE07_23910	COG3284	Transcriptional regulator
MLE07_23930	COG1129	ABC transporter
MLE07_23935	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_23940	COG1172	Belongs to the binding-protein-dependent transport system permease family
MLE07_23950	COG0572	uridine kinase
MLE07_23955	COG1082	Xylose isomerase domain protein TIM barrel
MLE07_23965	COG1126	abc transporter atp-binding protein
MLE07_23970	COG0765	amino acid transport
MLE07_23975	COG0765	amino acid transport
MLE07_23980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_23985	COG3608	succinylglutamate desuccinylase aspartoacylase
MLE07_23990	COG0006	proline dipeptidase activity
MLE07_23995	COG2423	ornithine cyclodeaminase activity
MLE07_24000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MLE07_24005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MLE07_24010	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MLE07_24015	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_24020	COG1522	sequence-specific DNA binding
MLE07_24045	COG0596	Alpha beta hydrolase
MLE07_24065	COG4178	(ABC) transporter
MLE07_24100	COG0640	Transcriptional regulator
MLE07_24140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MLE07_24150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MLE07_24240	COG1201	RNA secondary structure unwinding
MLE07_24270	COG3436	PFAM IS66 Orf2 family protein
MLE07_24275	COG4372	Transposase
MLE07_24305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MLE07_24305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MLE07_24375	COG3657	addiction module killer protein
MLE07_24470	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MLE07_24480	COG0583	DNA-binding transcription factor activity
MLE07_24485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MLE07_24485	COG1017	nitric oxide dioxygenase activity
MLE07_24490	COG0625	glutathione transferase activity
MLE07_24620	COG0730	response to heat
MLE07_24630	COG0431	NADPH-dependent FMN reductase
MLE07_24640	COG0798	PFAM Bile acid sodium symporter
MLE07_24655	COG0640	Transcriptional regulator
MLE07_24695	COG1192	Involved in chromosome partitioning
MLE07_24700	COG1475	DNA binding
MLE07_24705	COG1414	Transcriptional regulator
MLE07_24745	COG3838	Conjugal transfer protein Trbc
MLE07_24750	COG3702	type iv secretory pathway
MLE07_24760	COG3451	type IV secretory pathway VirB4
MLE07_24775	COG3704	protein secretion by the type IV secretion system
MLE07_24785	COG3736	Type IV secretory pathway, component VirB8
MLE07_24790	COG3504	Conjugal transfer protein
MLE07_24795	COG2948	multi-organism process
MLE07_24800	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
MLE07_24905	COG3831	ATPase activity
MLE07_24915	COG3505	Type IV secretory pathway VirD4
MLE07_24955	COG2197	response regulator
MLE07_24960	COG0604	alcohol dehydrogenase
MLE07_24960	COG3321	synthase
MLE07_24980	COG2188	Transcriptional regulator
MLE07_24985	COG0765	amino acid transport
MLE07_24990	COG0765	amino acid transport
MLE07_24995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_25000	COG1126	abc transporter atp-binding protein
MLE07_25015	COG0300	oxidoreductase activity
MLE07_25030	COG0840	transmembrane signaling receptor activity
MLE07_25045	COG5001	Diguanylate cyclase
MLE07_25045	COG3300	MHYT domain
MLE07_25050	COG0840	transmembrane signaling receptor activity
MLE07_25055	COG2207	Transcriptional regulator
MLE07_25105	COG2831	hemolysin activation secretion protein
MLE07_25130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MLE07_25145	COG1250	3-hydroxyacyl-CoA dehydrogenase
MLE07_25145	COG0824	Thioesterase
MLE07_25150	COG4770	biotin carboxylase activity
MLE07_25155	COG3842	ATPase activity
MLE07_25170	COG0318	PFAM AMP-dependent synthetase and ligase
MLE07_25180	COG1178	ABC-type Fe3 transport system permease component
MLE07_25195	COG2030	dehydratase
MLE07_25200	COG1028	Short-chain dehydrogenase reductase Sdr
MLE07_25230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MLE07_25245	COG2086	electron transfer activity
MLE07_25250	COG1802	Transcriptional regulator
MLE07_25255	COG0277	FAD linked oxidase domain protein
MLE07_25260	COG1126	abc transporter atp-binding protein
MLE07_25265	COG0765	amino acid transport
MLE07_25275	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_25280	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_25285	COG0395	ABC-type sugar transport system, permease component
MLE07_25290	COG1176	ABC-type spermidine putrescine transport system, permease component I
MLE07_25300	COG3842	ATPase activity
MLE07_25305	COG1473	amidohydrolase
MLE07_25310	COG1304	FMN binding
MLE07_25335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MLE07_25340	COG1396	sequence-specific DNA binding
MLE07_25345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MLE07_25370	COG0395	ABC-type sugar transport system, permease component
MLE07_25380	COG0583	DNA-binding transcription factor activity
MLE07_25440	COG3534	alpha-L-arabinofuranosidase
MLE07_25445	COG4603	Belongs to the binding-protein-dependent transport system permease family
MLE07_25450	COG4603	Belongs to the binding-protein-dependent transport system permease family
MLE07_25455	COG3845	ABC transporter
MLE07_25485	COG1760	l-serine dehydratase
MLE07_25490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MLE07_25500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MLE07_25500	COG0446	pyridine nucleotide-disulphide oxidoreductase
MLE07_25510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_25515	COG1917	Cupin 2, conserved barrel domain protein
MLE07_25515	COG4977	sequence-specific DNA binding
MLE07_25530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MLE07_25535	COG1012	belongs to the aldehyde dehydrogenase family
MLE07_25540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_25555	COG4176	ABC-type proline glycine betaine transport system permease component
MLE07_25560	COG4176	ABC-type proline glycine betaine transport system permease component
MLE07_25575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MLE07_25600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MLE07_25635	COG1609	Transcriptional regulator
MLE07_25645	COG0583	DNA-binding transcription factor activity
MLE07_25740	COG2826	transposase and inactivated derivatives, IS30 family
MLE07_25770	COG0431	NADPH-dependent FMN reductase
MLE07_25795	COG0640	Transcriptional regulator
MLE07_25810	COG0640	Transcriptional regulator
MLE07_25815	COG1475	DNA binding
MLE07_25820	COG1192	Involved in chromosome partitioning
MLE07_25830	COG4962	Type ii secretion system protein e
MLE07_25845	COG3451	type IV secretory pathway VirB4
MLE07_25850	COG5314	conjugation
MLE07_25860	COG3846	protein secretion by the type IV secretion system
MLE07_25865	COG3701	Conjugal transfer protein
MLE07_25895	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
MLE07_25900	COG1335	isochorismatase
MLE07_25905	COG4977	sequence-specific DNA binding
MLE07_25930	COG0402	S-adenosylhomocysteine deaminase activity
MLE07_25935	COG1228	amidohydrolase
MLE07_25940	COG2986	histidine ammonia-lyase
MLE07_25950	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MLE07_25965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MLE07_25980	COG0765	amino acid transport
MLE07_25995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MLE07_26010	COG2271	Major facilitator Superfamily
MLE07_26025	COG2204	response regulator
MLE07_26030	COG0784	Response regulator, receiver
MLE07_26030	COG2205	protein histidine kinase activity
MLE07_26035	COG2197	response regulator
MLE07_26060	COG4977	sequence-specific DNA binding
MLE07_26085	COG2271	Major facilitator Superfamily
MLE07_26090	COG4948	Mandelate Racemase Muconate Lactonizing
MLE07_26105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MLE07_26110	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MLE07_26155	COG2205	protein histidine kinase activity
MLE07_26160	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MLE07_26215	COG3831	ATPase activity
MLE07_26220	COG0776	regulation of translation
MLE07_26235	COG5489	Protein of unknown function (DUF736)
MLE07_26250	COG2824	Alkylphosphonate utilization operon protein PhnA
MLE07_26275	COG1475	DNA binding
MLE07_26340	COG0640	Transcriptional regulator
MLE07_26360	COG3447	MASE1 domain protein
MLE07_26360	COG5001	Diguanylate cyclase
MLE07_26360	COG5002	protein histidine kinase activity
MLE07_26390	COG3300	MHYT domain
MLE07_26390	COG5001	Diguanylate cyclase
MLE07_26400	COG4585	Histidine kinase
MLE07_26405	COG2197	response regulator
MLE07_26420	COG1280	lysine exporter protein (LysE YggA)
MLE07_26450	COG3077	Addiction module antitoxin, RelB DinJ family
MLE07_26475	COG0071	Belongs to the small heat shock protein (HSP20) family