locus-tag	class	description
FY138_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY138_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY138_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY138_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY138_00025	COG1420	regulation of RNA biosynthetic process
FY138_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY138_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY138_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY138_00050	COG1137	ATPase activity
FY138_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY138_00065	COG0616	signal peptide processing
FY138_00070	COG0776	regulation of translation
FY138_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY138_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY138_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY138_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY138_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY138_00115	COG0728	peptidoglycan biosynthetic process
FY138_00125	COG0180	Tryptophanyl-tRNA synthetase
FY138_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY138_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY138_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY138_00165	COG1702	phosphate starvation-inducible protein PhoH
FY138_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY138_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY138_00185	COG1396	sequence-specific DNA binding
FY138_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY138_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY138_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_00210	COG0242	peptide deformylase activity
FY138_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY138_00220	COG0101	tRNA pseudouridine synthase activity
FY138_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_00235	COG2171	N-acyltransferase activity
FY138_00245	COG0840	transmembrane signaling receptor activity
FY138_00250	COG1957	nucleoside hydrolase
FY138_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY138_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY138_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY138_00295	COG0706	membrane insertase activity
FY138_00300	COG0594	ribonuclease P activity
FY138_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY138_00310	COG0840	transmembrane signaling receptor activity
FY138_00325	COG2226	methyltransferase
FY138_00330	COG3842	ATPase activity
FY138_00335	COG1175	transmembrane transport
FY138_00340	COG0395	ABC-type sugar transport system, permease component
FY138_00355	COG0427	acetyl-CoA hydrolase
FY138_00365	COG3938	Belongs to the proline racemase family
FY138_00370	COG0418	dihydroorotase activity
FY138_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY138_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY138_00400	COG0166	Belongs to the GPI family
FY138_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY138_00410	COG3842	ATPase activity
FY138_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY138_00425	COG4774	siderophore transport
FY138_00470	COG2326	polyphosphate kinase activity
FY138_00475	COG5002	protein histidine kinase activity
FY138_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY138_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY138_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY138_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY138_00505	COG0745	RESPONSE REGULATOR receiver
FY138_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY138_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY138_00530	COG2967	ApaG domain
FY138_00545	COG0717	Belongs to the dCTP deaminase family
FY138_00600	COG3561	AntA/AntB antirepressor
FY138_00640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY138_00680	COG5484	DNA packaging
FY138_00680	COG3728	DNA packaging
FY138_00805	COG0582	viral genome integration into host DNA
FY138_00830	COG0419	ATPase involved in DNA repair
FY138_00850	COG1396	sequence-specific DNA binding
FY138_00890	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY138_00895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY138_00945	COG0167	dihydroorotate dehydrogenase activity
FY138_00980	COG1959	2 iron, 2 sulfur cluster binding
FY138_00985	COG1201	RNA secondary structure unwinding
FY138_01015	COG1960	acyl-CoA dehydrogenase activity
FY138_01020	COG0183	Belongs to the thiolase family
FY138_01025	COG1024	Enoyl-CoA hydratase
FY138_01025	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY138_01050	COG1320	monovalent cation:proton antiporter activity
FY138_01055	COG2212	antiporter activity
FY138_01060	COG1863	multisubunit Na H antiporter MnhE subunit
FY138_01065	COG0651	ATP synthesis coupled electron transport
FY138_01070	COG1006	Multisubunit Na H antiporter MnhC subunit
FY138_01075	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY138_01075	COG2111	Na H antiporter
FY138_01085	COG0840	transmembrane signaling receptor activity
FY138_01095	COG0745	RESPONSE REGULATOR receiver
FY138_01100	COG0643	Histidine kinase
FY138_01100	COG2198	Histidine kinase
FY138_01105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY138_01110	COG2201	protein-glutamate methylesterase activity
FY138_01115	COG0745	RESPONSE REGULATOR receiver
FY138_01120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY138_01130	COG1766	The M ring may be actively involved in energy transduction
FY138_01135	COG2771	luxR family
FY138_01145	COG0840	transmembrane signaling receptor activity
FY138_01145	COG2972	Histidine kinase
FY138_01150	COG2198	Histidine kinase
FY138_01150	COG2205	protein histidine kinase activity
FY138_01150	COG0784	Response regulator, receiver
FY138_01155	COG1970	mechanosensitive ion channel activity
FY138_01160	COG0436	Aminotransferase
FY138_01175	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY138_01180	COG0424	maF-like protein
FY138_01185	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY138_01195	COG5328	Belongs to the UPF0262 family
FY138_01200	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY138_01210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY138_01230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY138_01240	COG1338	Plays a role in the flagellum-specific transport system
FY138_01250	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY138_01260	COG1706	bacterial-type flagellum-dependent cell motility
FY138_01265	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY138_01270	COG4786	Flagellar basal body rod
FY138_01275	COG1677	Flagellar hook-basal body complex protein FliE
FY138_01280	COG1558	bacterial-type flagellum-dependent cell motility
FY138_01285	COG1815	bacterial-type flagellum-dependent cell motility
FY138_01295	COG1157	protein secretion by the type III secretion system
FY138_01300	COG4786	Flagellar basal body rod
FY138_01310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY138_01315	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY138_01320	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY138_01325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY138_01330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY138_01350	COG1360	Flagellar Motor Protein
FY138_01395	COG5443	negative regulation of bacterial-type flagellum assembly
FY138_01400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY138_01410	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY138_01450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY138_01455	COG1609	Transcriptional regulator
FY138_01460	COG1653	transport
FY138_01465	COG1175	transmembrane transport
FY138_01470	COG0395	ABC-type sugar transport system, permease component
FY138_01475	COG0366	Alpha amylase catalytic
FY138_01480	COG3842	ATPase activity
FY138_01495	COG0129	dihydroxy-acid dehydratase activity
FY138_01500	COG0363	glucosamine-6-phosphate deaminase activity
FY138_01505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY138_01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_01520	COG2081	HI0933 family
FY138_01540	COG2224	Isocitrate lyase
FY138_01555	COG3842	ATPase activity
FY138_01560	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_01565	COG1177	transmembrane transport
FY138_01580	COG2205	protein histidine kinase activity
FY138_01590	COG0248	Ppx GppA phosphatase
FY138_01595	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY138_01600	COG0477	Major facilitator Superfamily
FY138_01630	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY138_01635	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY138_01645	COG0142	geranyltranstransferase activity
FY138_01670	COG0752	glycyl-tRNA synthetase alpha subunit
FY138_01680	COG1704	LemA family
FY138_01685	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY138_01695	COG0751	glycine-tRNA ligase activity
FY138_01700	COG1683	Conserved Protein
FY138_01705	COG0840	transmembrane signaling receptor activity
FY138_01715	COG0151	Belongs to the GarS family
FY138_01720	COG2183	response to ionizing radiation
FY138_01725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY138_01750	COG0583	DNA-binding transcription factor activity
FY138_01770	COG0306	phosphate transporter
FY138_01780	COG0561	phosphatase activity
FY138_01785	COG0438	transferase activity, transferring glycosyl groups
FY138_01790	COG2186	Transcriptional regulator
FY138_01800	COG0583	DNA-binding transcription factor activity
FY138_01805	COG0277	FAD linked oxidase domain protein
FY138_01810	COG0277	FAD linked oxidase domain protein
FY138_01815	COG0247	lactate metabolic process
FY138_01825	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_01830	COG2818	Glycosylase
FY138_01840	COG2855	membrane
FY138_01845	COG0583	DNA-binding transcription factor activity
FY138_01875	COG0124	histidyl-tRNA synthetase
FY138_01885	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY138_01890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY138_01895	COG2259	Doxx family
FY138_01905	COG0459	protein refolding
FY138_01910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY138_01920	COG0196	riboflavin kinase activity
FY138_01925	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY138_01935	COG0590	tRNA wobble adenosine to inosine editing
FY138_01940	COG1187	pseudouridine synthase activity
FY138_01945	COG0742	ribosomal rna small subunit methyltransferase
FY138_01950	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY138_01960	COG0312	modulator of DNA gyrase
FY138_01965	COG0483	inositol monophosphate 1-phosphatase activity
FY138_01975	COG1519	Transferase
FY138_01985	COG1663	tetraacyldisaccharide 4'-kinase activity
FY138_01995	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY138_02000	COG0745	RESPONSE REGULATOR receiver
FY138_02005	COG5001	Diguanylate cyclase
FY138_02005	COG3300	MHYT domain
FY138_02010	COG3386	PFAM SMP-30 Gluconolaconase
FY138_02015	COG0800	Aldolase
FY138_02020	COG3734	2-keto-3-deoxy-galactonokinase
FY138_02025	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_02030	COG1414	Transcriptional regulator
FY138_02035	COG2197	response regulator
FY138_02050	COG0598	Magnesium transport protein CorA
FY138_02055	COG3158	transport of potassium into the cell
FY138_02070	COG0356	it plays a direct role in the translocation of protons across the membrane
FY138_02080	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY138_02085	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY138_02100	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY138_02120	COG0009	L-threonylcarbamoyladenylate synthase
FY138_02130	COG4638	Rieske (2fe-2S)
FY138_02155	COG1960	acyl-CoA dehydrogenase activity
FY138_02170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY138_02175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY138_02180	COG0840	transmembrane signaling receptor activity
FY138_02190	COG1522	sequence-specific DNA binding
FY138_02215	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY138_02220	COG1741	Belongs to the pirin family
FY138_02225	COG1722	exodeoxyribonuclease VII activity
FY138_02230	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY138_02235	COG1268	BioY protein
FY138_02240	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY138_02245	COG1122	ATPase activity
FY138_02250	COG3214	Protein conserved in bacteria
FY138_02255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY138_02255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY138_02260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY138_02280	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY138_02295	COG0259	pyridoxamine-phosphate oxidase activity
FY138_02325	COG0312	modulator of DNA gyrase
FY138_02340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY138_02345	COG0109	protoheme IX farnesyltransferase activity
FY138_02350	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY138_02365	COG3346	SURF1 family
FY138_02370	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY138_02375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY138_02380	COG0328	RNA-DNA hybrid ribonuclease activity
FY138_02390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY138_02390	COG0678	peroxiredoxin activity
FY138_02400	COG1678	Uncharacterized ACR, COG1678
FY138_02405	COG3237	CsbD-like
FY138_02415	COG5001	Diguanylate cyclase
FY138_02415	COG3300	MHYT domain
FY138_02420	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY138_02425	COG0612	Peptidase, M16
FY138_02450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY138_02455	COG1802	Transcriptional regulator
FY138_02470	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY138_02475	COG3609	addiction module antidote protein, CC2985 family
FY138_02480	COG3668	Plasmid stabilization system
FY138_02490	COG1194	a g-specific adenine glycosylase
FY138_02505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY138_02510	COG1196	nuclear chromosome segregation
FY138_02515	COG2514	catechol 2,3-dioxygenase activity
FY138_02520	COG0574	Belongs to the PEP-utilizing enzyme family
FY138_02520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY138_02530	COG1823	symporter activity
FY138_02555	COG0579	oxidoreductase
FY138_02570	COG2895	sulfate adenylyltransferase (ATP) activity
FY138_02575	COG0175	sulfate reduction
FY138_02580	COG0175	sulfate reduction
FY138_02585	COG1959	2 iron, 2 sulfur cluster binding
FY138_02590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY138_02595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY138_02600	COG4208	sulfate ABC transporter
FY138_02605	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY138_02615	COG2203	Gaf domain
FY138_02615	COG2200	EAL domain
FY138_02615	COG2199	diguanylate cyclase activity
FY138_02625	COG1309	transcriptional regulator
FY138_02630	COG1012	belongs to the aldehyde dehydrogenase family
FY138_02635	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY138_02665	COG0625	glutathione transferase activity
FY138_02675	COG0477	Major facilitator Superfamily
FY138_02685	COG3657	addiction module killer protein
FY138_02695	COG1793	dna ligase
FY138_02715	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_02720	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_02725	COG1846	Transcriptional regulator
FY138_02730	COG1764	response to oxidative stress
FY138_02745	COG0488	(ABC) transporter
FY138_02780	COG4221	oxidoreductase activity
FY138_02795	COG0433	COG0433 Predicted ATPase
FY138_02805	COG1733	regulation of RNA biosynthetic process
FY138_02810	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY138_02825	COG0656	L-ascorbic acid biosynthetic process
FY138_02830	COG3781	membrane
FY138_02835	COG2378	regulation of single-species biofilm formation
FY138_02845	COG4106	trans-aconitate 2-methyltransferase activity
FY138_02850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY138_02855	COG0840	transmembrane signaling receptor activity
FY138_02860	COG0583	DNA-binding transcription factor activity
FY138_02875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY138_02895	COG3909	cytochrome
FY138_02900	COG2010	Cytochrome c
FY138_02935	COG0789	Transcriptional regulator
FY138_02960	COG4175	Glycine betaine
FY138_02960	COG0517	IMP dehydrogenase activity
FY138_02965	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_02985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_02995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY138_02995	COG2169	Transcriptional regulator
FY138_03005	COG2514	catechol 2,3-dioxygenase activity
FY138_03020	COG1272	protein, Hemolysin III
FY138_03030	COG1280	lysine exporter protein (LysE YggA)
FY138_03035	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY138_03040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY138_03040	COG2111	Na H antiporter
FY138_03045	COG2111	Na H antiporter
FY138_03050	COG1006	Multisubunit Na H antiporter MnhC subunit
FY138_03055	COG0651	ATP synthesis coupled electron transport
FY138_03060	COG1863	multisubunit Na H antiporter MnhE subunit
FY138_03065	COG2212	antiporter activity
FY138_03070	COG1320	monovalent cation:proton antiporter activity
FY138_03075	COG4957	zinc ion binding
FY138_03090	COG2166	iron-sulfur cluster assembly
FY138_03100	COG2205	protein histidine kinase activity
FY138_03145	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY138_03150	COG2983	Belongs to the UPF0260 family
FY138_03165	COG2217	Heavy metal translocating P-type atpase
FY138_03195	COG2814	Major facilitator Superfamily
FY138_03200	COG1621	beta-fructofuranosidase activity
FY138_03205	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY138_03255	COG4695	Portal protein
FY138_03360	COG4235	cytochrome complex assembly
FY138_03365	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY138_03370	COG1138	Cytochrome C-type biogenesis protein
FY138_03375	COG3088	subunit of a heme lyase
FY138_03380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY138_03385	COG0745	RESPONSE REGULATOR receiver
FY138_03390	COG2205	protein histidine kinase activity
FY138_03395	COG3011	Protein conserved in bacteria
FY138_03400	COG3713	MltA-interacting MipA family protein
FY138_03405	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY138_03410	COG2202	Pas domain
FY138_03410	COG2205	protein histidine kinase activity
FY138_03420	COG0308	aminopeptidase N
FY138_03425	COG0697	spore germination
FY138_03440	COG0443	Heat shock 70 kDa protein
FY138_03475	COG0604	alcohol dehydrogenase
FY138_03480	COG1733	regulation of RNA biosynthetic process
FY138_03485	COG1968	undecaprenyl-diphosphatase activity
FY138_03490	COG2239	Acts as a magnesium transporter
FY138_03495	COG2814	Major facilitator Superfamily
FY138_03520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY138_03545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY138_03585	COG0741	lytic transglycosylase activity
FY138_03590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_03595	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY138_03600	COG0840	transmembrane signaling receptor activity
FY138_03610	COG1758	RNA polymerase activity
FY138_03630	COG0736	holo-[acyl-carrier-protein] synthase activity
FY138_03635	COG0681	Belongs to the peptidase S26 family
FY138_03640	COG0571	ribonuclease III activity
FY138_03645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY138_03655	COG0784	Response regulator, receiver
FY138_03660	COG1381	Involved in DNA repair and RecF pathway recombination
FY138_03670	COG2226	methyltransferase
FY138_03680	COG1418	mRNA catabolic process
FY138_03690	COG0346	lactoylglutathione lyase activity
FY138_03705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_03710	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY138_03715	COG0668	transmembrane transport
FY138_03725	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY138_03755	COG1742	UPF0060 membrane protein
FY138_03770	COG1183	phosphatidylcholine synthase activity
FY138_03775	COG0688	phosphatidylethanolamine metabolic process
FY138_03780	COG5265	(ABC) transporter
FY138_03820	COG2852	Protein conserved in bacteria
FY138_03825	COG0215	cysteine-tRNA ligase activity
FY138_03830	COG4221	oxidoreductase activity
FY138_03835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY138_03840	COG1286	toxin biosynthetic process
FY138_03855	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY138_03865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY138_03875	COG0305	Participates in initiation and elongation during chromosome replication
FY138_03895	COG0359	binds to the 23S rRNA
FY138_03905	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY138_03910	COG0360	Binds together with S18 to 16S ribosomal RNA
FY138_03920	COG0667	Aldo Keto reductase
FY138_03925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY138_03935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_03940	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY138_03950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY138_03955	COG1561	YicC-like family, N-terminal region
FY138_03960	COG0194	GDP metabolic process
FY138_03975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY138_03980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY138_03990	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY138_04005	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY138_04025	COG5001	Diguanylate cyclase
FY138_04025	COG3706	GGDEF domain
FY138_04025	COG2203	Gaf domain
FY138_04025	COG4251	negative regulation of phosphorylation
FY138_04030	COG3300	MHYT domain
FY138_04030	COG5001	Diguanylate cyclase
FY138_04035	COG4191	Histidine kinase
FY138_04040	COG4566	intracellular signal transduction
FY138_04050	COG0488	(ABC) transporter
FY138_04055	COG3706	GGDEF domain
FY138_04065	COG0105	UTP biosynthetic process
FY138_04085	COG0314	molybdopterin synthase activity
FY138_04095	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY138_04100	COG0322	excinuclease ABC activity
FY138_04105	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_04130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY138_04135	COG0243	molybdopterin cofactor binding
FY138_04150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY138_04155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY138_04160	COG2226	methyltransferase
FY138_04165	COG0628	permease
FY138_04175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY138_04180	COG0248	Ppx GppA phosphatase
FY138_04205	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY138_04215	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY138_04220	COG0477	Major facilitator Superfamily
FY138_04225	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY138_04235	COG0840	transmembrane signaling receptor activity
FY138_04240	COG0659	secondary active sulfate transmembrane transporter activity
FY138_04250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY138_04255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY138_04265	COG0113	porphobilinogen synthase activity
FY138_04285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY138_04290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY138_04295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY138_04295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY138_04305	COG1280	lysine exporter protein (LysE YggA)
FY138_04310	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY138_04315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY138_04320	COG2814	Major facilitator Superfamily
FY138_04325	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY138_04345	COG0416	fatty acid biosynthetic process
FY138_04350	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY138_04355	COG0776	regulation of translation
FY138_04390	COG0601	transmembrane transport
FY138_04395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_04400	COG0444	Belongs to the ABC transporter superfamily
FY138_04410	COG0747	negative chemotaxis
FY138_04420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY138_04425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY138_04440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY138_04445	COG0583	DNA-binding transcription factor activity
FY138_04450	COG0737	Belongs to the 5'-nucleotidase family
FY138_04470	COG2897	thiosulfate sulfurtransferase activity
FY138_04485	COG0415	Belongs to the DNA photolyase family
FY138_04495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY138_04525	COG3932	Exopolysaccharide synthesis, ExoD
FY138_04530	COG1238	metal cluster binding
FY138_04605	COG1612	heme a metabolic process
FY138_04615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY138_04620	COG0010	Belongs to the arginase family
FY138_04625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY138_04630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY138_04640	COG1832	CoA-binding protein
FY138_04670	COG2124	cytochrome p450
FY138_04675	COG2199	diguanylate cyclase activity
FY138_04680	COG0740	serine-type endopeptidase activity
FY138_04685	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY138_04690	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY138_04700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY138_04725	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_04730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_04735	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_04745	COG0649	NAD binding
FY138_04755	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY138_04760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY138_04770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY138_04775	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY138_04785	COG0713	ATP synthesis coupled electron transport
FY138_04800	COG1007	ATP synthesis coupled electron transport
FY138_04805	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY138_04805	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY138_04820	COG0442	prolyl-tRNA aminoacylation
FY138_04830	COG1136	(ABC) transporter
FY138_04845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY138_04865	COG0784	Response regulator, receiver
FY138_04875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY138_04880	COG0477	Major facilitator Superfamily
FY138_04895	COG0557	exoribonuclease II activity
FY138_04900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY138_04910	COG0758	DNA mediated transformation
FY138_04915	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY138_04925	COG0540	Belongs to the ATCase OTCase family
FY138_04940	COG1960	acyl-CoA dehydrogenase activity
FY138_04945	COG0456	acetyltransferase
FY138_04965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY138_04970	COG2824	Alkylphosphonate utilization operon protein PhnA
FY138_04975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY138_04980	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY138_04985	COG0154	amidase activity
FY138_04990	COG0456	acetyltransferase
FY138_04995	COG3811	Belongs to the UPF0386 family
FY138_05010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY138_05040	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY138_05045	COG0439	Biotin carboxylase
FY138_05050	COG0511	ligase activity, forming carbon-carbon bonds
FY138_05055	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY138_05065	COG0436	Aminotransferase
FY138_05085	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_05090	COG1530	ribonuclease E activity
FY138_05100	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY138_05120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY138_05125	COG0384	phenazine biosynthesis protein PhzF
FY138_05145	COG0633	Ferredoxin
FY138_05160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY138_05165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY138_05175	COG3768	UPF0283 membrane protein
FY138_05180	COG3106	COG3106 Predicted ATPase
FY138_05210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY138_05245	COG0537	adenosine 5'-monophosphoramidase activity
FY138_05270	COG0052	Belongs to the universal ribosomal protein uS2 family
FY138_05275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY138_05280	COG0528	UMP kinase activity
FY138_05285	COG0233	cytoplasmic translational termination
FY138_05290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY138_05300	COG0750	zinc metalloprotease
FY138_05305	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY138_05310	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY138_05315	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY138_05320	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY138_05325	COG3494	Protein of unknown function (DUF1009)
FY138_05330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY138_05335	COG2186	Transcriptional regulator
FY138_05345	COG0765	amino acid transport
FY138_05350	COG0765	amino acid transport
FY138_05360	COG0372	Belongs to the citrate synthase family
FY138_05375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY138_05400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY138_05405	COG1459	type II secretion system
FY138_05460	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY138_05465	COG0148	phosphopyruvate hydratase activity
FY138_05475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY138_05480	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY138_05480	COG0022	dehydrogenase e1 component
FY138_05485	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY138_05495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY138_05505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY138_05510	COG0697	spore germination
FY138_05525	COG2867	negative regulation of translational initiation
FY138_05530	COG1546	Belongs to the CinA family
FY138_05535	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY138_05535	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY138_05545	COG3852	Histidine kinase
FY138_05550	COG2204	response regulator
FY138_05555	COG5000	phosphorelay sensor kinase activity
FY138_05560	COG2204	response regulator
FY138_05565	COG0569	domain protein
FY138_05570	COG1923	regulation of RNA biosynthetic process
FY138_05575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY138_05580	COG3956	TIGRFAM MazG family protein
FY138_05590	COG1648	precorrin-2 dehydrogenase activity
FY138_05590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY138_05630	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY138_05630	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY138_05635	COG0509	glycine decarboxylation via glycine cleavage system
FY138_05640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_05665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY138_05670	COG0564	pseudouridine synthase activity
FY138_05690	COG0251	oxidation-reduction process
FY138_05695	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY138_05705	COG1671	Belongs to the UPF0178 family
FY138_05720	COG0450	alkyl hydroperoxide reductase
FY138_05725	COG0625	glutathione transferase activity
FY138_05735	COG2801	Transposase and inactivated derivatives
FY138_05740	COG0431	NADPH-dependent FMN reductase
FY138_05750	COG0798	PFAM Bile acid sodium symporter
FY138_05755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY138_05770	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY138_05770	COG0321	lipoyl(octanoyl) transferase activity
FY138_05775	COG0084	hydrolase, TatD family'
FY138_05780	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY138_05790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY138_05840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY138_05845	COG2095	MarC family integral membrane protein
FY138_05850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY138_05850	COG0617	tRNA 3'-terminal CCA addition
FY138_05850	COG0517	IMP dehydrogenase activity
FY138_05860	COG0629	single-stranded DNA binding
FY138_05865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY138_05875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY138_05895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY138_05900	COG1121	(ABC) transporter
FY138_05920	COG0667	Aldo Keto reductase
FY138_05930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY138_06015	COG2239	Acts as a magnesium transporter
FY138_06020	COG0243	molybdopterin cofactor binding
FY138_06030	COG0242	peptide deformylase activity
FY138_06040	COG2202	Pas domain
FY138_06040	COG2205	protein histidine kinase activity
FY138_06050	COG0321	lipoyl(octanoyl) transferase activity
FY138_06055	COG1064	alcohol dehydrogenase
FY138_06085	COG1862	Preprotein translocase
FY138_06105	COG2124	cytochrome p450
FY138_06120	COG0596	Alpha beta hydrolase
FY138_06130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_06135	COG0626	cystathionine gamma-synthase activity
FY138_06140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_06145	COG4597	amino acid ABC transporter
FY138_06150	COG0765	amino acid transport
FY138_06155	COG1126	abc transporter atp-binding protein
FY138_06170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY138_06185	COG0436	Aminotransferase
FY138_06215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY138_06225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY138_06230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_06235	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY138_06250	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY138_06255	COG1489	DNA binding
FY138_06260	COG0024	Methionine aminopeptidase
FY138_06265	COG2003	Belongs to the UPF0758 family
FY138_06280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY138_06305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY138_06310	COG0546	phosphoglycolate phosphatase activity
FY138_06320	COG0114	fumarate hydratase activity
FY138_06330	COG0504	CTP synthase activity
FY138_06340	COG0149	triose-phosphate isomerase activity
FY138_06350	COG0187	DNA topoisomerase II activity
FY138_06360	COG0740	serine-type endopeptidase activity
FY138_06370	COG0640	Transcriptional regulator
FY138_06375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY138_06380	COG0745	RESPONSE REGULATOR receiver
FY138_06395	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY138_06395	COG3264	Mechanosensitive ion channel
FY138_06460	COG1127	ABC transporter
FY138_06465	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY138_06470	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_06480	COG0281	malic enzyme
FY138_06480	COG0280	phosphate acetyltransferase
FY138_06490	COG0778	Nitroreductase
FY138_06495	COG0823	Involved in the tonB-independent uptake of proteins
FY138_06510	COG1368	sulfuric ester hydrolase activity
FY138_06535	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY138_06555	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY138_06575	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY138_06590	COG0318	PFAM AMP-dependent synthetase and ligase
FY138_06600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY138_06600	COG0512	Glutamine amidotransferase of anthranilate synthase
FY138_06605	COG0343	queuine tRNA-ribosyltransferase activity
FY138_06610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY138_06625	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY138_06640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY138_06645	COG0134	indole-3-glycerol-phosphate synthase activity
FY138_06650	COG0315	cyclic pyranopterin monophosphate synthase activity
FY138_06655	COG0303	'Molybdopterin
FY138_06660	COG3706	GGDEF domain
FY138_06670	COG0475	glutathione-regulated potassium exporter activity
FY138_06670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY138_06680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY138_06690	COG2814	Major facilitator Superfamily
FY138_06695	COG0746	molybdenum cofactor guanylyltransferase activity
FY138_06700	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY138_06705	COG0739	heme binding
FY138_06710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY138_06715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY138_06720	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY138_06725	COG0805	protein transport
FY138_06730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY138_06735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY138_06740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY138_06745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY138_06750	COG1472	Belongs to the glycosyl hydrolase 3 family
FY138_06760	COG0018	arginyl-trna synthetase
FY138_06765	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY138_06790	COG0525	valine-tRNA ligase activity
FY138_06800	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY138_06940	COG1525	nuclease
FY138_07015	COG3567	Phage-associated protein, HI1409 family
FY138_07030	COG5410	chromosome segregation
FY138_07065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY138_07245	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY138_07250	COG1058	Belongs to the CinA family
FY138_07250	COG1546	Belongs to the CinA family
FY138_07255	COG0589	response to stress
FY138_07260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY138_07270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY138_07280	COG0640	Transcriptional regulator
FY138_07285	COG1914	H( )-stimulated, divalent metal cation uptake system
FY138_07295	COG1132	(ABC) transporter
FY138_07300	COG0628	permease
FY138_07335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY138_07345	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY138_07355	COG0302	gtp cyclohydrolase
FY138_07360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY138_07365	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY138_07375	COG0517	IMP dehydrogenase activity
FY138_07375	COG0516	GMP reductase activity
FY138_07410	COG1760	l-serine dehydratase
FY138_07450	COG0583	DNA-binding transcription factor activity
FY138_07465	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY138_07465	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY138_07475	COG0347	Belongs to the P(II) protein family
FY138_07480	COG0174	glutamine synthetase
FY138_07510	COG0697	spore germination
FY138_07520	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY138_07530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY138_07560	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY138_07570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY138_07575	COG2186	Transcriptional regulator
FY138_07585	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY138_07590	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY138_07595	COG3845	ABC transporter
FY138_07600	COG1183	phosphatidylcholine synthase activity
FY138_07605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_07610	COG0679	Auxin Efflux Carrier
FY138_07615	COG0785	Cytochrome C biogenesis protein
FY138_07635	COG1278	Cold shock
FY138_07685	COG0577	efflux transmembrane transporter activity
FY138_07685	COG1136	(ABC) transporter
FY138_07690	COG1136	(ABC) transporter
FY138_07690	COG0577	efflux transmembrane transporter activity
FY138_07715	COG2151	metal-sulfur cluster biosynthetic enzyme
FY138_07720	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY138_07725	COG0719	Fe-S assembly protein
FY138_07730	COG0396	ATPase activity
FY138_07735	COG0719	Fe-S assembly protein
FY138_07740	COG1104	cysteine desulfurase activity
FY138_07745	COG2945	thiolester hydrolase activity
FY138_07750	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY138_07755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY138_07765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY138_07770	COG2833	Protein of unknown function (DUF455)
FY138_07775	COG0739	heme binding
FY138_07780	COG0513	Belongs to the DEAD box helicase family
FY138_07805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY138_07815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY138_07820	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY138_07825	COG0047	phosphoribosylformylglycinamidine synthase activity
FY138_07840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_07845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY138_07865	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY138_07870	COG2814	Major facilitator Superfamily
FY138_07875	COG0483	inositol monophosphate 1-phosphatase activity
FY138_07880	COG0483	inositol monophosphate 1-phosphatase activity
FY138_07885	COG0037	tRNA processing
FY138_07890	COG2066	Belongs to the glutaminase family
FY138_07895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY138_07900	COG0861	Integral membrane protein TerC family
FY138_07915	COG1280	lysine exporter protein (LysE YggA)
FY138_07925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY138_07930	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY138_07940	COG0538	isocitrate dehydrogenase activity
FY138_07950	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY138_07955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY138_07960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_07965	COG2313	pseudouridylate synthase activity
FY138_07975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_07980	COG4215	(ABC) transporter
FY138_07990	COG5425	PFAM Usg family protein
FY138_08000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_08005	COG1522	sequence-specific DNA binding
FY138_08010	COG1573	uracil-dna glycosylase
FY138_08020	COG2205	protein histidine kinase activity
FY138_08020	COG2202	Pas domain
FY138_08025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY138_08030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY138_08035	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY138_08050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY138_08055	COG0842	Transport permease protein
FY138_08060	COG1131	(ABC) transporter
FY138_08065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY138_08065	COG0730	response to heat
FY138_08085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY138_08090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY138_08110	COG0129	dihydroxy-acid dehydratase activity
FY138_08115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY138_08120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY138_08130	COG3739	integral membrane protein
FY138_08135	COG0203	ribosomal protein L17
FY138_08140	COG0202	RNA polymerase activity
FY138_08145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY138_08150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY138_08155	COG0563	adenylate kinase activity
FY138_08160	COG0201	protein transport
FY138_08165	COG0200	Binds to the 23S rRNA
FY138_08170	COG1841	ribosomal large subunit assembly
FY138_08175	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY138_08180	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY138_08185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY138_08190	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY138_08195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY138_08200	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY138_08205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY138_08210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY138_08215	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY138_08220	COG0255	Belongs to the universal ribosomal protein uL29 family
FY138_08225	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY138_08230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY138_08235	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY138_08240	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY138_08245	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY138_08250	COG0089	rRNA binding
FY138_08255	COG0088	Forms part of the polypeptide exit tunnel
FY138_08260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY138_08265	COG0051	transcription antitermination factor activity, RNA binding
FY138_08270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY138_08275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY138_08280	COG0049	tRNA binding
FY138_08285	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY138_08305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY138_08310	COG0085	RNA polymerase activity
FY138_08315	COG0222	ribosome binding
FY138_08320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY138_08325	COG0081	regulation of translation
FY138_08330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY138_08340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY138_08350	COG1086	Polysaccharide biosynthesis protein
FY138_08355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY138_08360	COG0861	Integral membrane protein TerC family
FY138_08365	COG3895	Periplasmic Protein
FY138_08385	COG1132	(ABC) transporter
FY138_08390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY138_08410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY138_08445	COG2205	protein histidine kinase activity
FY138_08445	COG2198	Histidine kinase
FY138_08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_08445	COG0784	Response regulator, receiver
FY138_08450	COG0784	Response regulator, receiver
FY138_08455	COG2202	Pas domain
FY138_08455	COG3920	Histidine kinase
FY138_08460	COG0784	Response regulator, receiver
FY138_08465	COG4251	negative regulation of phosphorylation
FY138_08480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY138_08485	COG1607	acyl-coa hydrolase
FY138_08505	COG2910	NAD(P)H-binding
FY138_08510	COG1733	regulation of RNA biosynthetic process
FY138_08525	COG0556	nucleotide-excision repair
FY138_08535	COG2382	esterase
FY138_08555	COG0484	heat shock protein binding
FY138_08575	COG3706	GGDEF domain
FY138_08595	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_08600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_08615	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY138_08625	COG2207	Transcriptional regulator
FY138_08630	COG1064	alcohol dehydrogenase
FY138_08635	COG1252	NADH dehydrogenase
FY138_08640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY138_08645	COG2197	response regulator
FY138_08650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY138_08685	COG0656	L-ascorbic acid biosynthetic process
FY138_08700	COG0440	acetolactate synthase activity
FY138_08705	COG0028	Belongs to the TPP enzyme family
FY138_08715	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY138_08720	COG0560	Phosphoserine phosphatase
FY138_08720	COG3830	Belongs to the UPF0237 family
FY138_08740	COG0330	HflC and HflK could
FY138_08745	COG0330	HflC and HflK could
FY138_08755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY138_08790	COG0277	FAD linked oxidase domain protein
FY138_08795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_08835	COG1335	isochorismatase
FY138_08860	COG2264	protein methyltransferase activity
FY138_08865	COG1999	signal sequence binding
FY138_08875	COG0835	chemotaxis
FY138_08885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY138_08890	COG0583	DNA-binding transcription factor activity
FY138_08900	COG1247	-acetyltransferase
FY138_08910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY138_08915	COG0497	DNA recombination
FY138_08920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY138_08930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY138_08935	COG0849	cell division
FY138_08940	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY138_08945	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY138_08950	COG0477	Major facilitator Superfamily
FY138_08955	COG5001	Diguanylate cyclase
FY138_08960	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY138_08965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY138_08970	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY138_08980	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY138_08985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY138_08995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY138_09010	COG0275	rRNA processing
FY138_09015	COG2001	Belongs to the MraZ family
FY138_09040	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY138_09070	COG4106	trans-aconitate 2-methyltransferase activity
FY138_09090	COG2226	methyltransferase
FY138_09100	COG2267	carboxylic ester hydrolase activity
FY138_09105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY138_09120	COG0251	oxidation-reduction process
FY138_09135	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_09140	COG2814	Major facilitator Superfamily
FY138_09170	COG1012	belongs to the aldehyde dehydrogenase family
FY138_09175	COG0174	glutamine synthetase
FY138_09180	COG0531	amino acid
FY138_09190	COG1737	Transcriptional regulator
FY138_09195	COG2182	Extracellular solute-binding protein
FY138_09210	COG3842	ATPase activity
FY138_09270	COG2968	Membrane
FY138_09280	COG0432	Pfam Uncharacterised protein family UPF0047
FY138_09295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY138_09300	COG0358	DNA primase activity
FY138_09320	COG0505	Belongs to the CarA family
FY138_09325	COG0534	Mate efflux family protein
FY138_09340	COG2321	neutral zinc metallopeptidase
FY138_09355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY138_09365	COG3706	GGDEF domain
FY138_09380	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY138_09390	COG1522	sequence-specific DNA binding
FY138_09395	COG0492	ferredoxin-NADP+ reductase activity
FY138_09400	COG0583	DNA-binding transcription factor activity
FY138_09410	COG1902	pentaerythritol trinitrate reductase activity
FY138_09435	COG0387	Pfam Sodium calcium exchanger
FY138_09440	COG0436	Aminotransferase
FY138_09445	COG2199	diguanylate cyclase activity
FY138_09445	COG2200	EAL domain
FY138_09460	COG1278	Cold shock
FY138_09465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY138_09475	COG1846	Transcriptional regulator
FY138_09480	COG0745	RESPONSE REGULATOR receiver
FY138_09490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY138_09510	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY138_09520	COG1496	oxidoreductase activity
FY138_09535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY138_09545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY138_09560	COG0840	transmembrane signaling receptor activity
FY138_09565	COG1012	belongs to the aldehyde dehydrogenase family
FY138_09570	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY138_09575	COG5001	Diguanylate cyclase
FY138_09575	COG3300	MHYT domain
FY138_09580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY138_09585	COG5001	Diguanylate cyclase
FY138_09595	COG0193	aminoacyl-tRNA hydrolase activity
FY138_09605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY138_09630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY138_09640	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY138_09640	COG2857	Cytochrome c1
FY138_09660	COG1132	(ABC) transporter
FY138_09670	COG1132	(ABC) transporter
FY138_09680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY138_09695	COG0408	coproporphyrinogen oxidase activity
FY138_09710	COG0617	tRNA 3'-terminal CCA addition
FY138_09725	COG0714	Associated with various cellular activities
FY138_09745	COG0454	-acetyltransferase
FY138_09760	COG0477	Major facilitator Superfamily
FY138_09770	COG0435	Glutathione S-transferase
FY138_09775	COG0494	nUDIX hydrolase
FY138_09785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY138_09790	COG3135	benzoate transporter
FY138_09815	COG0740	serine-type endopeptidase activity
FY138_09830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY138_09835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY138_09860	COG4175	Glycine betaine
FY138_09880	COG1435	thymidine kinase activity
FY138_09905	COG4771	TonB-dependent receptor
FY138_09905	COG1629	transport
FY138_09915	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY138_09915	COG0512	Glutamine amidotransferase of anthranilate synthase
FY138_09930	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY138_09940	COG0366	Alpha amylase catalytic
FY138_09945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_09965	COG1160	GTP binding
FY138_09985	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY138_09995	COG0024	Methionine aminopeptidase
FY138_10005	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_10025	COG0583	DNA-binding transcription factor activity
FY138_10040	COG0402	S-adenosylhomocysteine deaminase activity
FY138_10050	COG1304	FMN binding
FY138_10060	COG1309	transcriptional regulator
FY138_10065	COG1686	Belongs to the peptidase S11 family
FY138_10075	COG2351	hydroxyisourate hydrolase activity
FY138_10080	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY138_10105	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY138_10115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_10115	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY138_10125	COG0513	Belongs to the DEAD box helicase family
FY138_10135	COG2259	Doxx family
FY138_10140	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_10150	COG2308	Evidence 4 Homologs of previously reported genes of
FY138_10160	COG1305	Transglutaminase-like
FY138_10185	COG4214	carbohydrate transport
FY138_10195	COG4213	ABC transporter substrate-binding protein
FY138_10250	COG2948	multi-organism process
FY138_10260	COG3701	Conjugal transfer protein
FY138_10265	COG3846	protein secretion by the type IV secretion system
FY138_10280	COG3451	type IV secretory pathway VirB4
FY138_10295	COG4962	Type ii secretion system protein e
FY138_10320	COG0583	DNA-binding transcription factor activity
FY138_10330	COG1566	PFAM secretion protein HlyD family protein
FY138_10345	COG2207	Transcriptional regulator
FY138_10350	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_10360	COG0583	DNA-binding transcription factor activity
FY138_10370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY138_10385	COG0583	DNA-binding transcription factor activity
FY138_10395	COG0741	lytic transglycosylase activity
FY138_10420	COG1192	Involved in chromosome partitioning
FY138_10455	COG2814	Major facilitator Superfamily
FY138_10465	COG5489	Protein of unknown function (DUF736)
FY138_10480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY138_10510	COG1204	response to ionizing radiation
FY138_10525	COG0514	ATP-dependent DNA helicase (RecQ)
FY138_10575	COG0583	DNA-binding transcription factor activity
FY138_10580	COG1902	pentaerythritol trinitrate reductase activity
FY138_10585	COG0583	DNA-binding transcription factor activity
FY138_10600	COG1335	isochorismatase
FY138_10605	COG0583	DNA-binding transcription factor activity
FY138_10610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY138_10620	COG4584	PFAM Integrase catalytic
FY138_10635	COG0840	transmembrane signaling receptor activity
FY138_10650	COG0646	methionine synthase
FY138_10650	COG1410	methionine synthase
FY138_10665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_10695	COG1215	transferase activity, transferring glycosyl groups
FY138_10725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY138_10740	COG2346	COG2346, Truncated hemoglobins
FY138_10760	COG1309	transcriptional regulator
FY138_10775	COG0494	nUDIX hydrolase
FY138_10785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_10790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_10820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY138_10825	COG0830	nickel cation binding
FY138_10830	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY138_10845	COG0804	urea catabolic process
FY138_10850	COG1442	glycosyl transferase family 8
FY138_10855	COG3755	Protein conserved in bacteria
FY138_10865	COG0832	Belongs to the urease beta subunit family
FY138_10870	COG3813	Protein conserved in bacteria
FY138_10875	COG0831	urea catabolic process
FY138_10880	COG0829	nickel cation binding
FY138_10900	COG0411	ABC transporter
FY138_10910	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY138_10925	COG0174	glutamine synthetase
FY138_10930	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_10935	COG5002	protein histidine kinase activity
FY138_10935	COG2198	Histidine kinase
FY138_10935	COG0784	Response regulator, receiver
FY138_10950	COG0726	polysaccharide deacetylase
FY138_10985	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY138_11060	COG0564	pseudouridine synthase activity
FY138_11070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY138_11080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY138_11105	COG0346	lactoylglutathione lyase activity
FY138_11115	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY138_11125	COG2832	Protein of unknown function (DUF454)
FY138_11130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY138_11135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_11140	COG4558	Periplasmic binding protein
FY138_11150	COG3721	Heme iron utilization protein
FY138_11165	COG3655	Transcriptional regulator
FY138_11190	COG2205	protein histidine kinase activity
FY138_11230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_11235	COG4605	iron ion homeostasis
FY138_11240	COG4604	ABC transporter, ATP-binding protein
FY138_11245	COG0783	Belongs to the Dps family
FY138_11260	COG0840	transmembrane signaling receptor activity
FY138_11260	COG2972	Histidine kinase
FY138_11265	COG0656	L-ascorbic acid biosynthetic process
FY138_11270	COG2814	Major facilitator Superfamily
FY138_11280	COG0583	DNA-binding transcription factor activity
FY138_11285	COG0657	acetylesterase activity
FY138_11290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_11310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY138_11315	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY138_11320	COG0288	reversible hydration of carbon dioxide
FY138_11330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY138_11350	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY138_11355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY138_11360	COG0778	Nitroreductase
FY138_11365	COG2267	carboxylic ester hydrolase activity
FY138_11370	COG0251	oxidation-reduction process
FY138_11375	COG1335	isochorismatase
FY138_11380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_11390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_11405	COG1175	transmembrane transport
FY138_11410	COG0395	ABC-type sugar transport system, permease component
FY138_11415	COG3842	ATPase activity
FY138_11420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_11430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY138_11445	COG4608	Belongs to the ABC transporter superfamily
FY138_11450	COG0444	Belongs to the ABC transporter superfamily
FY138_11455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_11460	COG0601	transmembrane transport
FY138_11515	COG2159	amidohydrolase
FY138_11520	COG1960	acyl-CoA dehydrogenase activity
FY138_11550	COG0745	RESPONSE REGULATOR receiver
FY138_11560	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_11560	COG1902	pentaerythritol trinitrate reductase activity
FY138_11565	COG3842	ATPase activity
FY138_11575	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_11580	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_11585	COG0745	RESPONSE REGULATOR receiver
FY138_11595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY138_11600	COG0583	DNA-binding transcription factor activity
FY138_11605	COG1278	Cold shock
FY138_11645	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY138_11650	COG1309	transcriptional regulator
FY138_11655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_11660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_11670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY138_11675	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY138_11695	COG0583	DNA-binding transcription factor activity
FY138_11700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_11705	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY138_11710	COG4149	molybdate abc transporter
FY138_11715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY138_11730	COG2022	thiamine diphosphate biosynthetic process
FY138_11745	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY138_11755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_11765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY138_11785	COG1132	(ABC) transporter
FY138_11790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY138_11835	COG4166	transmembrane transport
FY138_11840	COG0601	transmembrane transport
FY138_11845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_11860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY138_11865	COG3142	Participates in the control of copper homeostasis
FY138_11870	COG2814	Major facilitator Superfamily
FY138_11885	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_11890	COG1737	Transcriptional regulator
FY138_11900	COG3842	ATPase activity
FY138_11910	COG0395	ABC-type sugar transport system, permease component
FY138_11930	COG2188	Transcriptional regulator
FY138_11935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY138_11940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY138_11945	COG1940	carbohydrate kinase activity
FY138_11955	COG0671	phosphoesterase, PA-phosphatase related
FY138_11960	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY138_11965	COG0156	8-amino-7-oxononanoate synthase activity
FY138_11975	COG0729	surface antigen
FY138_11985	COG0835	chemotaxis
FY138_11995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY138_12000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY138_12005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY138_12010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY138_12015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY138_12020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY138_12035	COG4974	Belongs to the 'phage' integrase family
FY138_12060	COG1280	lysine exporter protein (LysE YggA)
FY138_12070	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY138_12075	COG0567	Dehydrogenase, E1 component
FY138_12080	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY138_12085	COG0045	succinate-CoA ligase (ADP-forming) activity
FY138_12090	COG0039	L-malate dehydrogenase activity
FY138_12095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY138_12145	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY138_12150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY138_12155	COG0181	hydroxymethylbilane synthase activity
FY138_12195	COG1872	DUF167
FY138_12200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY138_12210	COG1217	gtp-binding protein TYPA
FY138_12215	COG0339	signal peptide processing
FY138_12220	COG1846	Transcriptional regulator
FY138_12230	COG0137	argininosuccinate synthase activity
FY138_12240	COG1280	lysine exporter protein (LysE YggA)
FY138_12245	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY138_12250	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY138_12260	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY138_12275	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY138_12280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY138_12285	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY138_12295	COG4181	ATPase activity
FY138_12305	COG0670	Belongs to the BI1 family
FY138_12320	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY138_12325	COG4133	protoheme IX ABC transporter activity
FY138_12330	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY138_12335	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY138_12360	COG2917	probably involved in intracellular septation
FY138_12365	COG0552	protein localization to endoplasmic reticulum
FY138_12370	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY138_12375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY138_12390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY138_12395	COG0287	Prephenate dehydrogenase
FY138_12395	COG1605	Chorismate mutase
FY138_12400	COG0228	four-way junction DNA binding
FY138_12405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY138_12410	COG0336	Belongs to the RNA methyltransferase TrmD family
FY138_12420	COG0335	large ribosomal subunit rRNA binding
FY138_12425	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY138_12430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_12445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY138_12465	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY138_12485	COG0488	(ABC) transporter
FY138_12495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY138_12505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY138_12510	COG0142	geranyltranstransferase activity
FY138_12515	COG2885	chlorophyll binding
FY138_12520	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY138_12525	COG2223	nitrite transmembrane transporter activity
FY138_12530	COG1349	DNA-binding transcription factor activity
FY138_12535	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY138_12540	COG2197	response regulator
FY138_12545	COG1132	(ABC) transporter
FY138_12555	COG3459	Glycosyltransferase 36 associated
FY138_12560	COG1473	amidohydrolase
FY138_12565	COG0579	oxidoreductase
FY138_12575	COG0129	dihydroxy-acid dehydratase activity
FY138_12580	COG2084	Dehydrogenase
FY138_12585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_12590	COG0277	FAD linked oxidase domain protein
FY138_12595	COG2186	Transcriptional regulator
FY138_12605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY138_12610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY138_12615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_12620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY138_12630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY138_12635	COG0495	leucyl-tRNA aminoacylation
FY138_12650	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY138_12655	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY138_12670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_12675	COG1946	Acyl-CoA thioesterase
FY138_12680	COG0347	Belongs to the P(II) protein family
FY138_12685	COG0004	ammonium transporteR
FY138_12690	COG1674	ftsk spoiiie
FY138_12695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY138_12710	COG0745	RESPONSE REGULATOR receiver
FY138_12720	COG1329	Transcriptional regulator
FY138_12730	COG2270	Major facilitator Superfamily
FY138_12745	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_12760	COG0494	nUDIX hydrolase
FY138_12765	COG2861	carbohydrate metabolic process
FY138_12770	COG0793	Belongs to the peptidase S41A family
FY138_12780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY138_12785	COG0799	negative regulation of ribosome biogenesis
FY138_12790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY138_12795	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY138_12800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY138_12805	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY138_12820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY138_12825	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY138_12850	COG0066	3-isopropylmalate dehydratase activity
FY138_12855	COG0473	3-isopropylmalate dehydrogenase activity
FY138_12860	COG1858	cytochrome C peroxidase
FY138_12865	COG1797	cobyrinic acid a,c-diamide synthase activity
FY138_12875	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY138_12940	COG1492	cobalamin metabolic process
FY138_12955	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_12960	COG3254	rhamnose metabolic process
FY138_12965	COG0246	Mannitol dehydrogenase
FY138_12970	COG1063	alcohol dehydrogenase
FY138_12995	COG1129	ABC transporter
FY138_13000	COG2186	Transcriptional regulator
FY138_13005	COG2721	sulfolactate sulfo-lyase activity
FY138_13010	COG0138	bifunctional purine biosynthesis protein purh
FY138_13020	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY138_13020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY138_13025	COG0501	Belongs to the peptidase M48B family
FY138_13045	COG0357	Ribosomal RNA small subunit methyltransferase G
FY138_13050	COG0445	tRNA wobble uridine modification
FY138_13055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY138_13060	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY138_13065	COG1981	membrane
FY138_13070	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY138_13075	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY138_13080	COG0424	maF-like protein
FY138_13085	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY138_13090	COG0237	dephospho-CoA kinase activity
FY138_13100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY138_13105	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY138_13115	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY138_13140	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY138_13155	COG0135	phosphoribosylanthranilate isomerase activity
FY138_13160	COG0133	tryptophan synthase activity
FY138_13165	COG0159	tryptophan synthase activity
FY138_13170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY138_13185	COG1074	ATP-dependent DNA helicase activity
FY138_13195	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY138_13200	COG0802	atpase or kinase
FY138_13205	COG2205	protein histidine kinase activity
FY138_13210	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY138_13215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY138_13220	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY138_13220	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY138_13225	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY138_13230	COG0642	Histidine kinase
FY138_13235	COG0745	RESPONSE REGULATOR receiver
FY138_13240	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY138_13250	COG1652	LysM domain
FY138_13255	COG1072	(Pantothenic acid kinase))
FY138_13260	COG0140	phosphoribosyl-ATP diphosphatase activity
FY138_13265	COG0107	imidazoleglycerol-phosphate synthase activity
FY138_13270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY138_13275	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY138_13285	COG0131	Imidazoleglycerol-phosphate dehydratase
FY138_13290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY138_13295	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY138_13305	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY138_13320	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY138_13330	COG1643	Atp-dependent helicase
FY138_13375	COG1940	carbohydrate kinase activity
FY138_13395	COG1072	(Pantothenic acid kinase))
FY138_13405	COG1780	Probably involved in ribonucleotide reductase function
FY138_13425	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY138_13455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_13465	COG2813	Specifically methylates the guanine in position
FY138_13470	COG1185	polyribonucleotide nucleotidyltransferase activity
FY138_13475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY138_13480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY138_13485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY138_13490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY138_13490	COG3064	Membrane
FY138_13505	COG0779	Required for maturation of 30S ribosomal subunits
FY138_13510	COG2814	Major facilitator Superfamily
FY138_13520	COG2951	lytic endotransglycosylase activity
FY138_13525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY138_13535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY138_13540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY138_13555	COG2816	NAD+ diphosphatase activity
FY138_13560	COG0077	Prephenate dehydratase
FY138_13560	COG1605	Chorismate mutase
FY138_13565	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY138_13570	COG3474	cytochrome
FY138_13580	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY138_13585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY138_13590	COG1278	Cold shock
FY138_13595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_13605	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY138_13605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY138_13610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY138_13640	COG2900	Belongs to the SlyX family
FY138_13650	COG0484	heat shock protein binding
FY138_13655	COG0443	Heat shock 70 kDa protein
FY138_13670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY138_13675	COG1744	ABC transporter substrate-binding protein PnrA-like
FY138_13680	COG3845	ABC transporter
FY138_13685	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY138_13690	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY138_13695	COG0295	cytidine deaminase activity
FY138_13700	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY138_13705	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY138_13710	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY138_13720	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY138_13725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY138_13730	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY138_13740	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY138_13745	COG1845	cytochrome c oxidase, subunit III
FY138_13750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY138_13755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY138_13760	COG0477	Major facilitator Superfamily
FY138_13765	COG0067	glutamate synthase
FY138_13765	COG0069	glutamate synthase activity
FY138_13765	COG0070	glutamate synthase
FY138_13770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY138_13785	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY138_13795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY138_13825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_13845	COG0848	biopolymer transport protein
FY138_13855	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY138_13870	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY138_13875	COG3454	Phosphonate metabolism
FY138_13880	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY138_13885	COG3639	organic phosphonate transmembrane transporter activity
FY138_13890	COG3639	organic phosphonate transmembrane transporter activity
FY138_13900	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY138_13910	COG4778	phosphonate C-P lyase system protein PhnL
FY138_13915	COG4107	phosphonate C-P lyase system protein PhnK
FY138_13920	COG3627	carbon phosphorus lyase activity
FY138_13925	COG3626	phosphonate metabolism
FY138_13930	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY138_13935	COG3624	Phosphonate C-P lyase system protein PhnG
FY138_13940	COG2188	Transcriptional regulator
FY138_13945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY138_13950	COG0837	glucose binding
FY138_13955	COG1803	Methylglyoxal synthase
FY138_13960	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY138_13965	COG4166	transmembrane transport
FY138_13970	COG4174	ABC transporter (Permease)
FY138_13975	COG4239	(ABC) transporter, permease
FY138_13980	COG4172	Belongs to the ABC transporter superfamily
FY138_13985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_13990	COG0174	glutamine synthetase
FY138_13995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_14000	COG3265	gluconokinase activity
FY138_14005	COG1174	glycine betaine transport
FY138_14010	COG1125	glycine betaine transport
FY138_14015	COG1174	glycine betaine transport
FY138_14020	COG1732	Glycine betaine
FY138_14030	COG1959	2 iron, 2 sulfur cluster binding
FY138_14035	COG1840	ABC-type Fe3 transport system, periplasmic component
FY138_14045	COG4269	membrane
FY138_14060	COG0697	spore germination
FY138_14075	COG0791	NLP P60 protein
FY138_14085	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY138_14090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY138_14125	COG4964	Belongs to the GSP D family
FY138_14170	COG3422	double-strand break repair
FY138_14175	COG3757	hydrolase, family 25
FY138_14180	COG0697	spore germination
FY138_14185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_14200	COG0492	ferredoxin-NADP+ reductase activity
FY138_14215	COG0481	GTPase activity
FY138_14220	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY138_14235	COG1396	sequence-specific DNA binding
FY138_14250	COG1917	Cupin 2, conserved barrel domain protein
FY138_14250	COG2169	Transcriptional regulator
FY138_14255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY138_14280	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY138_14285	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY138_14290	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY138_14300	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY138_14305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY138_14305	COG0072	phenylalanine-tRNA ligase activity
FY138_14310	COG0667	Aldo Keto reductase
FY138_14330	COG4977	sequence-specific DNA binding
FY138_14355	COG1570	exodeoxyribonuclease VII activity
FY138_14360	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_14370	COG1846	Transcriptional regulator
FY138_14380	COG2309	aminopeptidase activity
FY138_14390	COG1393	Belongs to the ArsC family
FY138_14405	COG1309	transcriptional regulator
FY138_14415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY138_14415	COG0519	Catalyzes the synthesis of GMP from XMP
FY138_14430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY138_14460	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY138_14470	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY138_14480	COG1968	undecaprenyl-diphosphatase activity
FY138_14495	COG0284	orotidine-5'-phosphate decarboxylase activity
FY138_14505	COG3963	phosphatidate phosphatase activity
FY138_14515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY138_14520	COG0792	nuclease activity
FY138_14535	COG1175	transmembrane transport
FY138_14540	COG0395	ABC-type sugar transport system, permease component
FY138_14545	COG3842	ATPase activity
FY138_14555	COG0189	ligase activity
FY138_14565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY138_14570	COG1280	lysine exporter protein (LysE YggA)
FY138_14575	COG0756	dUTP diphosphatase activity
FY138_14580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY138_14585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY138_14600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY138_14605	COG2226	methyltransferase
FY138_14610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY138_14615	COG1024	Enoyl-CoA hydratase
FY138_14620	COG0268	Binds directly to 16S ribosomal RNA
FY138_14645	COG0640	Transcriptional regulator
FY138_14685	COG4178	(ABC) transporter
FY138_14710	COG1082	Xylose isomerase domain protein TIM barrel
FY138_14715	COG0572	uridine kinase
FY138_14725	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_14730	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_14735	COG1129	ABC transporter
FY138_14755	COG3284	Transcriptional regulator
FY138_14760	COG1063	alcohol dehydrogenase
FY138_14770	COG0110	maltose O-acetyltransferase activity
FY138_14775	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY138_14800	COG0488	(ABC) transporter
FY138_14805	COG5265	(ABC) transporter
FY138_14810	COG3181	Tripartite tricarboxylate transporter family receptor
FY138_14815	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY138_14825	COG3237	CsbD-like
FY138_14845	COG0395	ABC-type sugar transport system, permease component
FY138_14850	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY138_14860	COG0483	inositol monophosphate 1-phosphatase activity
FY138_14870	COG0405	Gamma-glutamyltransferase
FY138_14875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_14880	COG0601	transmembrane transport
FY138_14885	COG0747	negative chemotaxis
FY138_14890	COG2186	Transcriptional regulator
FY138_14900	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_14905	COG4172	Belongs to the ABC transporter superfamily
FY138_14910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_14915	COG0601	transmembrane transport
FY138_14920	COG0747	negative chemotaxis
FY138_14925	COG2186	Transcriptional regulator
FY138_14935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_14940	COG2223	nitrite transmembrane transporter activity
FY138_14950	COG3383	formate dehydrogenase (NAD+) activity
FY138_14970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY138_14985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_14995	COG0765	amino acid transport
FY138_15000	COG0765	amino acid transport
FY138_15005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_15020	COG3938	Belongs to the proline racemase family
FY138_15030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_15040	COG0765	amino acid transport
FY138_15055	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY138_15060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_15070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY138_15075	COG0784	Response regulator, receiver
FY138_15090	COG0842	Transport permease protein
FY138_15095	COG0842	Transport permease protein
FY138_15095	COG1129	ABC transporter
FY138_15100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_15105	COG1486	melibiose metabolic process
FY138_15110	COG4172	Belongs to the ABC transporter superfamily
FY138_15115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_15120	COG0601	transmembrane transport
FY138_15125	COG0747	negative chemotaxis
FY138_15130	COG1486	melibiose metabolic process
FY138_15155	COG1940	carbohydrate kinase activity
FY138_15160	COG2182	Extracellular solute-binding protein
FY138_15165	COG1175	transmembrane transport
FY138_15170	COG0395	ABC-type sugar transport system, permease component
FY138_15175	COG0165	Argininosuccinate lyase
FY138_15180	COG3842	ATPase activity
FY138_15185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_15190	COG3119	arylsulfatase activity
FY138_15200	COG0583	DNA-binding transcription factor activity
FY138_15205	COG1120	ATPase activity
FY138_15210	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_15215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_15225	COG4774	siderophore transport
FY138_15235	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY138_15250	COG2205	protein histidine kinase activity
FY138_15255	COG0745	RESPONSE REGULATOR receiver
FY138_15260	COG1566	PFAM secretion protein HlyD family protein
FY138_15275	COG1392	Phosphate transport regulator
FY138_15280	COG0306	phosphate transporter
FY138_15285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY138_15295	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY138_15305	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_15310	COG3300	MHYT domain
FY138_15310	COG5001	Diguanylate cyclase
FY138_15330	COG2186	Transcriptional regulator
FY138_15335	COG0601	transmembrane transport
FY138_15340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_15345	COG0444	Belongs to the ABC transporter superfamily
FY138_15355	COG3842	ATPase activity
FY138_15360	COG0395	ABC-type sugar transport system, permease component
FY138_15375	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_15375	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_15380	COG1609	Transcriptional regulator
FY138_15390	COG0210	DNA helicase
FY138_15395	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY138_15400	COG1088	dTDP-glucose 4,6-dehydratase activity
FY138_15405	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY138_15410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY138_15425	COG3754	Rhamnan synthesis protein F
FY138_15430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY138_15450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY138_15460	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY138_15465	COG1216	Glycosyl transferase, family 2
FY138_15465	COG1442	glycosyl transferase family 8
FY138_15480	COG1132	(ABC) transporter
FY138_15490	COG0583	DNA-binding transcription factor activity
FY138_15495	COG0667	Aldo Keto reductase
FY138_15515	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY138_15530	COG0300	oxidoreductase activity
FY138_15535	COG0584	glycerophosphoryl diester phosphodiesterase
FY138_15540	COG1940	carbohydrate kinase activity
FY138_15550	COG3712	iron ion homeostasis
FY138_15555	COG4774	siderophore transport
FY138_15560	COG2814	Major facilitator Superfamily
FY138_15580	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY138_15590	COG3842	ATPase activity
FY138_15595	COG1175	transmembrane transport
FY138_15600	COG0395	ABC-type sugar transport system, permease component
FY138_15605	COG1609	Transcriptional regulator
FY138_15615	COG0673	inositol 2-dehydrogenase activity
FY138_15620	COG1082	Xylose isomerase domain protein TIM barrel
FY138_15635	COG1609	Transcriptional regulator
FY138_15640	COG0183	Belongs to the thiolase family
FY138_15645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY138_15655	COG1414	Transcriptional regulator
FY138_15670	COG0583	DNA-binding transcription factor activity
FY138_15680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY138_15685	COG3485	protocatechuate 3,4-dioxygenase
FY138_15690	COG3485	protocatechuate 3,4-dioxygenase
FY138_15695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY138_15700	COG0765	amino acid transport
FY138_15705	COG0765	amino acid transport
FY138_15710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_15715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_15720	COG1126	abc transporter atp-binding protein
FY138_15725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY138_15730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY138_15755	COG4172	Belongs to the ABC transporter superfamily
FY138_15760	COG0747	negative chemotaxis
FY138_15770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_15785	COG0683	leucine binding
FY138_15800	COG0411	ABC transporter
FY138_15815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_15820	COG3962	Belongs to the TPP enzyme family
FY138_15830	COG3718	enzyme involved in inositol metabolism
FY138_15840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_15845	COG1609	Transcriptional regulator
FY138_15850	COG1846	Transcriptional regulator
FY138_15860	COG0523	cobalamin synthesis protein
FY138_15900	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY138_15920	COG0800	Aldolase
FY138_15925	COG2954	triphosphatase activity
FY138_15935	COG1054	Belongs to the UPF0176 family
FY138_15940	COG3300	MHYT domain
FY138_15940	COG5001	Diguanylate cyclase
FY138_15950	COG2011	ABC-type metal ion transport system permease component
FY138_15955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY138_15960	COG0778	Nitroreductase
FY138_15970	COG2115	Belongs to the xylose isomerase family
FY138_15975	COG1070	Carbohydrate kinase
FY138_15980	COG1609	Transcriptional regulator
FY138_16000	COG1309	transcriptional regulator
FY138_16005	COG1253	flavin adenine dinucleotide binding
FY138_16010	COG3273	potassium ion transport
FY138_16010	COG0471	metal ion transport
FY138_16015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY138_16020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY138_16025	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY138_16035	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY138_16040	COG1121	(ABC) transporter
FY138_16045	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY138_16050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY138_16060	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_16065	COG1414	Transcriptional regulator
FY138_16070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY138_16090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY138_16140	COG0395	ABC-type sugar transport system, permease component
FY138_16145	COG1175	transmembrane transport
FY138_16155	COG2390	Transcriptional regulator
FY138_16160	COG4172	Belongs to the ABC transporter superfamily
FY138_16165	COG1473	amidohydrolase
FY138_16175	COG0601	transmembrane transport
FY138_16180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_16190	COG0693	protein deglycase activity
FY138_16195	COG0154	amidase activity
FY138_16200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_16210	COG0747	negative chemotaxis
FY138_16215	COG0583	DNA-binding transcription factor activity
FY138_16220	COG4608	Belongs to the ABC transporter superfamily
FY138_16225	COG0444	Belongs to the ABC transporter superfamily
FY138_16230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_16235	COG0601	transmembrane transport
FY138_16240	COG0747	negative chemotaxis
FY138_16255	COG1473	amidohydrolase
FY138_16260	COG2814	Major facilitator Superfamily
FY138_16265	COG0583	DNA-binding transcription factor activity
FY138_16270	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY138_16280	COG3842	ATPase activity
FY138_16290	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_16300	COG1609	Transcriptional regulator
FY138_16305	COG0583	DNA-binding transcription factor activity
FY138_16310	COG1960	acyl-CoA dehydrogenase activity
FY138_16315	COG4774	siderophore transport
FY138_16315	COG1629	transport
FY138_16325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_16335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_16340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_16350	COG2375	cellular response to nickel ion
FY138_16360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY138_16365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY138_16365	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY138_16375	COG1169	isochorismate synthase
FY138_16380	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY138_16385	COG1535	isochorismatase
FY138_16385	COG3433	isochorismatase activity
FY138_16390	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_16405	COG3005	denitrification pathway
FY138_16415	COG0243	molybdopterin cofactor binding
FY138_16430	COG4459	periplasmic nitrate reductase
FY138_16465	COG0826	peptidase U32
FY138_16475	COG3189	MarR family transcriptional regulator
FY138_16480	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY138_16510	COG3256	nitric oxide reductase
FY138_16515	COG0714	Associated with various cellular activities
FY138_16575	COG0673	inositol 2-dehydrogenase activity
FY138_16585	COG1609	Transcriptional regulator
FY138_16590	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_16595	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_16600	COG1129	ABC transporter
FY138_16605	COG1879	ABC-type sugar transport system periplasmic component
FY138_16615	COG0583	DNA-binding transcription factor activity
FY138_16630	COG1609	Transcriptional regulator
FY138_16635	COG0673	inositol 2-dehydrogenase activity
FY138_16645	COG1653	transport
FY138_16650	COG1175	transmembrane transport
FY138_16655	COG0395	ABC-type sugar transport system, permease component
FY138_16660	COG3842	ATPase activity
FY138_16675	COG1253	flavin adenine dinucleotide binding
FY138_16700	COG5001	Diguanylate cyclase
FY138_16700	COG3300	MHYT domain
FY138_16830	COG0477	Major facilitator Superfamily
FY138_16850	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_16860	COG1879	ABC-type sugar transport system periplasmic component
FY138_16870	COG1063	alcohol dehydrogenase
FY138_16885	COG1136	(ABC) transporter
FY138_16900	COG1309	transcriptional regulator
FY138_16920	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY138_16930	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_16930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_16940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_16945	COG0047	phosphoribosylformylglycinamidine synthase activity
FY138_16955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_16960	COG1012	belongs to the aldehyde dehydrogenase family
FY138_16965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_16975	COG4175	Glycine betaine
FY138_16975	COG3448	diguanylate cyclase activity
FY138_16985	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_16990	COG3938	Belongs to the proline racemase family
FY138_16995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY138_17030	COG1733	regulation of RNA biosynthetic process
FY138_17080	COG0477	Major facilitator Superfamily
FY138_17090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY138_17095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY138_17110	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_17120	COG0395	ABC-type sugar transport system, permease component
FY138_17145	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_17150	COG1349	DNA-binding transcription factor activity
FY138_17155	COG1069	ribulokinase activity
FY138_17175	COG1940	carbohydrate kinase activity
FY138_17190	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_17195	COG1177	transmembrane transport
FY138_17205	COG3842	ATPase activity
FY138_17260	COG0577	efflux transmembrane transporter activity
FY138_17260	COG1136	(ABC) transporter
FY138_17285	COG1845	cytochrome c oxidase, subunit III
FY138_17290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY138_17295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY138_17300	COG3474	cytochrome
FY138_17330	COG3842	ATPase activity
FY138_17335	COG0395	ABC-type sugar transport system, permease component
FY138_17340	COG1175	transmembrane transport
FY138_17345	COG1653	transport
FY138_17350	COG1012	belongs to the aldehyde dehydrogenase family
FY138_17355	COG1024	Enoyl-CoA hydratase
FY138_17375	COG4702	Belongs to the UPF0303 family
FY138_17380	COG1629	transport
FY138_17380	COG4774	siderophore transport
FY138_17385	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY138_17390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_17395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_17400	COG1120	ATPase activity
FY138_17415	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY138_17425	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY138_17430	COG1177	transmembrane transport
FY138_17435	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_17440	COG3842	ATPase activity
FY138_17465	COG1335	isochorismatase
FY138_17480	COG0583	DNA-binding transcription factor activity
FY138_17485	COG2318	DinB family
FY138_17515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY138_17545	COG0778	Nitroreductase
FY138_17565	COG0277	FAD linked oxidase domain protein
FY138_17585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_17590	COG4172	Belongs to the ABC transporter superfamily
FY138_17600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_17610	COG0431	NADPH-dependent FMN reductase
FY138_17630	COG1522	sequence-specific DNA binding
FY138_17635	COG2376	Dihydroxyacetone kinase
FY138_17645	COG4221	oxidoreductase activity
FY138_17650	COG0625	glutathione transferase activity
FY138_17660	COG1566	PFAM secretion protein HlyD family protein
FY138_17670	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY138_17675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY138_17690	COG0534	Mate efflux family protein
FY138_17725	COG1733	regulation of RNA biosynthetic process
FY138_17735	COG1136	(ABC) transporter
FY138_17735	COG0577	efflux transmembrane transporter activity
FY138_17740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_17750	COG0745	RESPONSE REGULATOR receiver
FY138_17770	COG3209	COG3209 Rhs family protein
FY138_17800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_17825	COG3177	Filamentation induced by cAMP protein fic
FY138_17840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_17845	COG4597	amino acid ABC transporter
FY138_17850	COG0765	amino acid transport
FY138_17875	COG0747	negative chemotaxis
FY138_17880	COG0601	transmembrane transport
FY138_17885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_17890	COG0444	Belongs to the ABC transporter superfamily
FY138_17895	COG4608	Belongs to the ABC transporter superfamily
FY138_17915	COG4213	ABC transporter substrate-binding protein
FY138_17920	COG1129	ABC transporter
FY138_17925	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_17940	COG0667	Aldo Keto reductase
FY138_17965	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_17970	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_17975	COG1129	ABC transporter
FY138_17985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_17995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_18005	COG0747	negative chemotaxis
FY138_18010	COG0747	negative chemotaxis
FY138_18015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_18025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_18030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_18035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY138_18045	COG0405	Gamma-glutamyltransferase
FY138_18075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_18080	COG0436	Aminotransferase
FY138_18095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_18100	COG0765	amino acid transport
FY138_18110	COG1126	abc transporter atp-binding protein
FY138_18120	COG2186	Transcriptional regulator
FY138_18140	COG1846	Transcriptional regulator
FY138_18145	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_18155	COG0583	DNA-binding transcription factor activity
FY138_18190	COG0583	DNA-binding transcription factor activity
FY138_18210	COG1280	lysine exporter protein (LysE YggA)
FY138_18215	COG3920	Histidine kinase
FY138_18240	COG0753	catalase activity
FY138_18260	COG1278	Cold shock
FY138_18300	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_18305	COG1902	pentaerythritol trinitrate reductase activity
FY138_18310	COG4221	oxidoreductase activity
FY138_18315	COG1309	transcriptional regulator
FY138_18330	COG1280	lysine exporter protein (LysE YggA)
FY138_18340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY138_18385	COG0741	lytic transglycosylase activity
FY138_18385	COG1196	nuclear chromosome segregation
FY138_18385	COG0739	heme binding
FY138_18390	COG0542	response to heat
FY138_18400	COG2890	protein-(glutamine-N5) methyltransferase activity
FY138_18405	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY138_18415	COG0527	aspartate kinase activity
FY138_18430	COG0019	diaminopimelate decarboxylase activity
FY138_18445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY138_18465	COG0784	Response regulator, receiver
FY138_18480	COG1522	sequence-specific DNA binding
FY138_18490	COG1116	anion transmembrane transporter activity
FY138_18495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_18500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_18505	COG1012	belongs to the aldehyde dehydrogenase family
FY138_18510	COG0583	DNA-binding transcription factor activity
FY138_18515	COG0435	Glutathione S-transferase
FY138_18530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY138_18535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_18540	COG0189	ligase activity
FY138_18560	COG0693	protein deglycase activity
FY138_18590	COG3685	Protein conserved in bacteria
FY138_18595	COG4993	Dehydrogenase
FY138_18610	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_18615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY138_18660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_18675	COG0246	Mannitol dehydrogenase
FY138_18680	COG4608	Belongs to the ABC transporter superfamily
FY138_18685	COG0444	Belongs to the ABC transporter superfamily
FY138_18690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_18695	COG0601	transmembrane transport
FY138_18700	COG0747	negative chemotaxis
FY138_18710	COG4221	oxidoreductase activity
FY138_18740	COG0539	negative regulation of cytoplasmic translation
FY138_18745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY138_18775	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY138_18780	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY138_18810	COG1294	oxidase, subunit
FY138_18820	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY138_18825	COG4988	ABC transporter
FY138_18835	COG1063	alcohol dehydrogenase
FY138_18840	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_18845	COG2084	Dehydrogenase
FY138_18855	COG1522	sequence-specific DNA binding
FY138_18860	COG1794	racemase activity, acting on amino acids and derivatives
FY138_18875	COG0058	SHG alpha-glucan phosphorylase activity
FY138_18880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY138_18885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY138_18890	COG0297	glycogen (starch) synthase activity
FY138_18895	COG0033	Phosphoglucomutase
FY138_18900	COG1523	belongs to the glycosyl hydrolase 13 family
FY138_18930	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_18930	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY138_18945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_18950	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY138_18970	COG1215	transferase activity, transferring glycosyl groups
FY138_18975	COG2327	Polysaccharide pyruvyl transferase
FY138_18980	COG0463	Glycosyl transferase, family 2
FY138_18985	COG2244	polysaccharide biosynthetic process
FY138_18990	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY138_18995	COG2273	Hydrolase Family 16
FY138_19000	COG0438	transferase activity, transferring glycosyl groups
FY138_19005	COG1215	transferase activity, transferring glycosyl groups
FY138_19010	COG1215	transferase activity, transferring glycosyl groups
FY138_19015	COG1215	transferase activity, transferring glycosyl groups
FY138_19020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY138_19025	COG0489	protein tyrosine kinase activity
FY138_19025	COG3206	protein involved in exopolysaccharide biosynthesis
FY138_19030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY138_19035	COG0784	Response regulator, receiver
FY138_19035	COG4191	Histidine kinase
FY138_19050	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_19055	COG3448	diguanylate cyclase activity
FY138_19055	COG4175	Glycine betaine
FY138_19070	COG0564	pseudouridine synthase activity
FY138_19075	COG0500	methyltransferase
FY138_19085	COG2133	pyrroloquinoline quinone binding
FY138_19095	COG2197	response regulator
FY138_19100	COG4585	Histidine kinase
FY138_19105	COG1879	ABC-type sugar transport system periplasmic component
FY138_19110	COG1129	ABC transporter
FY138_19115	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_19125	COG3386	PFAM SMP-30 Gluconolaconase
FY138_19130	COG2137	regulation of response to DNA damage stimulus
FY138_19135	COG3474	cytochrome
FY138_19145	COG1120	ATPase activity
FY138_19160	COG4774	siderophore transport
FY138_19165	COG0583	DNA-binding transcription factor activity
FY138_19175	COG2194	sulfuric ester hydrolase activity
FY138_19190	COG0477	Major facilitator Superfamily
FY138_19215	COG0673	inositol 2-dehydrogenase activity
FY138_19220	COG0697	spore germination
FY138_19230	COG0010	Belongs to the arginase family
FY138_19245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY138_19250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY138_19255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY138_19260	COG0156	8-amino-7-oxononanoate synthase activity
FY138_19265	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY138_19315	COG0671	phosphoesterase, PA-phosphatase related
FY138_19320	COG0745	RESPONSE REGULATOR receiver
FY138_19325	COG2205	protein histidine kinase activity
FY138_19335	COG0477	Major facilitator Superfamily
FY138_19340	COG0583	DNA-binding transcription factor activity
FY138_19360	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY138_19375	COG0346	lactoylglutathione lyase activity
FY138_19380	COG0583	DNA-binding transcription factor activity
FY138_19410	COG1215	transferase activity, transferring glycosyl groups
FY138_19430	COG0840	transmembrane signaling receptor activity
FY138_19445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_19460	COG2828	Protein conserved in bacteria
FY138_19465	COG0583	DNA-binding transcription factor activity
FY138_19470	COG1846	Transcriptional regulator
FY138_19495	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_19500	COG1309	transcriptional regulator
FY138_19505	COG2207	Transcriptional regulator
FY138_19520	COG1566	PFAM secretion protein HlyD family protein
FY138_19540	COG0395	ABC-type sugar transport system, permease component
FY138_19545	COG4166	transmembrane transport
FY138_19550	COG0601	transmembrane transport
FY138_19555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_19560	COG4172	Belongs to the ABC transporter superfamily
FY138_19600	COG0402	S-adenosylhomocysteine deaminase activity
FY138_19605	COG1228	amidohydrolase
FY138_19610	COG2986	histidine ammonia-lyase
FY138_19620	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY138_19650	COG1192	Involved in chromosome partitioning
FY138_19655	COG1475	DNA binding
FY138_19660	COG1414	Transcriptional regulator
FY138_19680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY138_19685	COG4771	TonB-dependent receptor
FY138_19695	COG0366	Alpha amylase catalytic
FY138_19700	COG4770	biotin carboxylase activity
FY138_19705	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_19710	COG4336	lyase activity
FY138_19715	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_19720	COG1914	H( )-stimulated, divalent metal cation uptake system
FY138_19725	COG1802	Transcriptional regulator
FY138_19730	COG3707	response regulator
FY138_19740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_19745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_19750	COG1116	anion transmembrane transporter activity
FY138_19755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY138_19765	COG0243	molybdopterin cofactor binding
FY138_19770	COG1648	precorrin-2 dehydrogenase activity
FY138_19770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY138_19785	COG3842	ATPase activity
FY138_19800	COG0395	ABC-type sugar transport system, permease component
FY138_19815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY138_19830	COG0071	Belongs to the small heat shock protein (HSP20) family
FY138_19875	COG1879	ABC-type sugar transport system periplasmic component
FY138_19880	COG1129	ABC transporter
FY138_19885	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_19895	COG0667	Aldo Keto reductase
FY138_19900	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY138_19905	COG1830	Aldolase
FY138_19910	COG1070	Carbohydrate kinase
FY138_19915	COG0840	transmembrane signaling receptor activity
FY138_19930	COG0436	Aminotransferase
FY138_19940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY138_19950	COG3842	ATPase activity
FY138_19955	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_19960	COG1984	allophanate hydrolase subunit 2
FY138_19965	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY138_19975	COG0439	Biotin carboxylase
FY138_19980	COG0511	ligase activity, forming carbon-carbon bonds
FY138_19985	COG0697	spore germination
FY138_19990	COG0697	spore germination
FY138_20005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_20020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_20025	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_20030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_20035	COG4221	oxidoreductase activity
FY138_20040	COG0765	amino acid transport
FY138_20045	COG0765	amino acid transport
FY138_20055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_20060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_20065	COG1063	alcohol dehydrogenase
FY138_20080	COG1304	FMN binding
FY138_20105	COG3842	ATPase activity
FY138_20115	COG0395	ABC-type sugar transport system, permease component
FY138_20120	COG1175	transmembrane transport
FY138_20135	COG2186	Transcriptional regulator
FY138_20140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY138_20145	COG0488	(ABC) transporter
FY138_20160	COG2307	Protein conserved in bacteria
FY138_20160	COG2308	Evidence 4 Homologs of previously reported genes of
FY138_20200	COG1454	alcohol dehydrogenase
FY138_20205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY138_20215	COG0747	negative chemotaxis
FY138_20220	COG0601	transmembrane transport
FY138_20225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_20235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_20280	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY138_20305	COG1082	Xylose isomerase domain protein TIM barrel
FY138_20310	COG0673	inositol 2-dehydrogenase activity
FY138_20315	COG1082	Xylose isomerase domain protein TIM barrel
FY138_20335	COG1609	Transcriptional regulator
FY138_20340	COG2986	histidine ammonia-lyase
FY138_20345	COG4175	Glycine betaine
FY138_20345	COG0517	IMP dehydrogenase activity
FY138_20350	COG4176	ABC-type proline glycine betaine transport system permease component
FY138_20390	COG2186	Transcriptional regulator
FY138_20395	COG1027	Aspartate ammonia-lyase
FY138_20405	COG0252	asparaginase activity
FY138_20415	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY138_20420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY138_20425	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY138_20430	COG2205	protein histidine kinase activity
FY138_20445	COG0067	glutamate synthase
FY138_20445	COG0070	glutamate synthase
FY138_20445	COG0069	glutamate synthase activity
FY138_20460	COG2205	protein histidine kinase activity
FY138_20475	COG2951	lytic endotransglycosylase activity
FY138_20480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY138_20505	COG0330	HflC and HflK could
FY138_20510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY138_20515	COG0737	Belongs to the 5'-nucleotidase family
FY138_20525	COG5310	Homospermidine synthase
FY138_20535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY138_20540	COG1164	Oligoendopeptidase f
FY138_20545	COG2204	response regulator
FY138_20550	COG3108	Peptidase M15
FY138_20555	COG0469	pyruvate kinase activity
FY138_20575	COG3750	Belongs to the UPF0335 family
FY138_20580	COG0457	Tetratricopeptide repeat
FY138_20585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY138_20590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY138_20595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY138_20625	COG0483	inositol monophosphate 1-phosphatase activity
FY138_20645	COG1132	(ABC) transporter
FY138_20650	COG0254	rRNA binding
FY138_20670	COG3588	fructose-bisphosphate aldolase
FY138_20675	COG0126	phosphoglycerate kinase activity
FY138_20715	COG1253	flavin adenine dinucleotide binding
FY138_20725	COG1692	metallophosphoesterase
FY138_20740	COG0217	transcriptional regulatory protein
FY138_20745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_20750	COG0840	transmembrane signaling receptor activity
FY138_20755	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY138_20760	COG0632	four-way junction helicase activity
FY138_20765	COG2255	four-way junction helicase activity
FY138_20780	COG0494	nUDIX hydrolase
FY138_20790	COG0824	Thioesterase
FY138_20810	COG0823	Involved in the tonB-independent uptake of proteins
FY138_20815	COG2885	chlorophyll binding
FY138_20825	COG0037	tRNA processing
FY138_20830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY138_20835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY138_20850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY138_20865	COG0482	sulfurtransferase activity
FY138_20895	COG2835	tetraacyldisaccharide 4'-kinase activity
FY138_20900	COG2373	Large extracellular alpha-helical protein
FY138_20905	COG4953	penicillin-binding protein 1C
FY138_20915	COG1473	amidohydrolase
FY138_20920	COG1686	Belongs to the peptidase S11 family
FY138_20925	COG0523	cobalamin synthesis protein
FY138_20930	COG0425	Belongs to the sulfur carrier protein TusA family
FY138_20930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY138_20935	COG3034	peptidoglycan biosynthetic process
FY138_20940	COG0825	malonyl-CoA metabolic process
FY138_20945	COG4974	Belongs to the 'phage' integrase family
FY138_20955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY138_20960	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY138_21000	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY138_21005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY138_21025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY138_21030	COG2226	methyltransferase
FY138_21035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY138_21040	COG0287	Prephenate dehydrogenase
FY138_21050	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY138_21070	COG2884	Cell division ATP-binding protein ftsE
FY138_21105	COG0165	Argininosuccinate lyase
FY138_21110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY138_21120	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY138_21130	COG2086	electron transfer activity
FY138_21140	COG2096	Adenosyltransferase
FY138_21150	COG0300	oxidoreductase activity
FY138_21160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY138_21170	COG1396	sequence-specific DNA binding
FY138_21170	COG3800	Transcriptional regulator
FY138_21175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY138_21180	COG0625	glutathione transferase activity
FY138_21195	COG4770	biotin carboxylase activity
FY138_21200	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY138_21200	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY138_21205	COG0346	lactoylglutathione lyase activity
FY138_21220	COG4213	ABC transporter substrate-binding protein
FY138_21225	COG4214	carbohydrate transport
FY138_21230	COG1129	ABC transporter
FY138_21235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY138_21245	COG1396	sequence-specific DNA binding
FY138_21300	COG3833	ABC-type maltose transport systems, permease component
FY138_21305	COG3842	ATPase activity
FY138_21320	COG2273	Hydrolase Family 16
FY138_21320	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY138_21325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY138_21340	COG0438	transferase activity, transferring glycosyl groups
FY138_21345	COG0438	transferase activity, transferring glycosyl groups
FY138_21365	COG3206	protein involved in exopolysaccharide biosynthesis
FY138_21365	COG0489	protein tyrosine kinase activity
FY138_21375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY138_21390	COG2244	polysaccharide biosynthetic process
FY138_21455	COG0697	spore germination
FY138_21460	COG0653	protein targeting
FY138_21465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY138_21470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY138_21480	COG0494	nUDIX hydrolase
FY138_21495	COG2226	methyltransferase
FY138_21500	COG1040	competence protein
FY138_21510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY138_21520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY138_21535	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY138_21540	COG4150	thiosulfate binding
FY138_21550	COG4208	sulfate ABC transporter
FY138_21555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY138_21560	COG4335	DNA alkylation repair
FY138_21575	COG5001	Diguanylate cyclase
FY138_21580	COG2264	protein methyltransferase activity
FY138_21595	COG3254	rhamnose metabolic process
FY138_21600	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_21605	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_21610	COG1129	ABC transporter
FY138_21620	COG1349	DNA-binding transcription factor activity
FY138_21625	COG3347	Dehydrogenase
FY138_21625	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_21630	COG4952	isomerase
FY138_21635	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY138_21640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY138_21660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY138_21665	COG1960	acyl-CoA dehydrogenase activity
FY138_21675	COG0183	Belongs to the thiolase family
FY138_21680	COG1960	acyl-CoA dehydrogenase activity
FY138_21690	COG0022	dehydrogenase e1 component
FY138_21700	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY138_21705	COG2391	methyltransferase activity
FY138_21715	COG0640	Transcriptional regulator
FY138_21720	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY138_21720	COG3453	Protein conserved in bacteria
FY138_21730	COG0300	oxidoreductase activity
FY138_21745	COG2186	Transcriptional regulator
FY138_21755	COG0601	transmembrane transport
FY138_21765	COG0444	Belongs to the ABC transporter superfamily
FY138_21770	COG4608	Belongs to the ABC transporter superfamily
FY138_21900	COG2369	cell adhesion
FY138_21905	COG4383	Mu-like prophage protein gp29
FY138_21910	COG4373	Mu-like prophage FluMu protein gp28
FY138_22045	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_22050	COG1733	regulation of RNA biosynthetic process
FY138_22060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22085	COG1473	amidohydrolase
FY138_22090	COG0747	negative chemotaxis
FY138_22105	COG4166	transmembrane transport
FY138_22110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22115	COG0583	DNA-binding transcription factor activity
FY138_22125	COG0667	Aldo Keto reductase
FY138_22135	COG0444	Belongs to the ABC transporter superfamily
FY138_22150	COG0747	negative chemotaxis
FY138_22160	COG1960	acyl-CoA dehydrogenase activity
FY138_22190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY138_22205	COG1959	2 iron, 2 sulfur cluster binding
FY138_22210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22220	COG1473	amidohydrolase
FY138_22230	COG1126	abc transporter atp-binding protein
FY138_22235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_22245	COG0583	DNA-binding transcription factor activity
FY138_22260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_22270	COG1522	sequence-specific DNA binding
FY138_22275	COG4172	Belongs to the ABC transporter superfamily
FY138_22280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_22315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_22320	COG1012	belongs to the aldehyde dehydrogenase family
FY138_22325	COG0473	3-isopropylmalate dehydrogenase activity
FY138_22330	COG1012	belongs to the aldehyde dehydrogenase family
FY138_22375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_22380	COG1120	ATPase activity
FY138_22390	COG2226	methyltransferase
FY138_22405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_22410	COG1120	ATPase activity
FY138_22415	COG1595	DNA-templated transcription, initiation
FY138_22435	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY138_22440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_22460	COG0673	inositol 2-dehydrogenase activity
FY138_22465	COG0673	inositol 2-dehydrogenase activity
FY138_22475	COG1175	transmembrane transport
FY138_22480	COG0395	ABC-type sugar transport system, permease component
FY138_22485	COG3842	ATPase activity
FY138_22495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_22500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_22505	COG2197	response regulator
FY138_22510	COG0601	transmembrane transport
FY138_22515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_22535	COG0747	negative chemotaxis
FY138_22550	COG1446	asparaginase
FY138_22555	COG0583	DNA-binding transcription factor activity
FY138_22560	COG0601	transmembrane transport
FY138_22565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_22580	COG0747	negative chemotaxis
FY138_22585	COG1473	amidohydrolase
FY138_22600	COG1129	ABC transporter
FY138_22605	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_22610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY138_22615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY138_22625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY138_22640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_22650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_22655	COG2079	MmgE PrpD family protein
FY138_22660	COG1126	abc transporter atp-binding protein
FY138_22665	COG0765	amino acid transport
FY138_22680	COG0281	malic enzyme
FY138_22680	COG0280	phosphate acetyltransferase
FY138_22685	COG0583	DNA-binding transcription factor activity
FY138_22710	COG1175	transmembrane transport
FY138_22715	COG0395	ABC-type sugar transport system, permease component
FY138_22730	COG0673	inositol 2-dehydrogenase activity
FY138_22735	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY138_22740	COG0720	synthase
FY138_22745	COG0602	queuosine metabolic process
FY138_22750	COG0673	inositol 2-dehydrogenase activity
FY138_22760	COG3842	ATPase activity
FY138_22775	COG1653	transport
FY138_22780	COG1609	Transcriptional regulator
FY138_22795	COG2094	Belongs to the DNA glycosylase MPG family
FY138_22805	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_22815	COG1376	ErfK ybiS ycfS ynhG family protein
FY138_22820	COG0840	transmembrane signaling receptor activity
FY138_22825	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY138_22835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY138_22840	COG1596	polysaccharide export
FY138_22845	COG3307	-O-antigen
FY138_22875	COG2197	response regulator
FY138_22885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_22910	COG2942	2-epimerase
FY138_22920	COG1215	transferase activity, transferring glycosyl groups
FY138_22940	COG1473	amidohydrolase
FY138_22950	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_22955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY138_22960	COG1301	dicarboxylic acid transport
FY138_22965	COG4191	Histidine kinase
FY138_22970	COG2204	response regulator
FY138_22985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_22990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY138_22995	COG1522	sequence-specific DNA binding
FY138_23000	COG0351	phosphomethylpyrimidine kinase
FY138_23005	COG0352	thiamine-phosphate diphosphorylase activity
FY138_23010	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY138_23015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_23020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_23030	COG1501	Belongs to the glycosyl hydrolase 31 family
FY138_23035	COG0395	ABC-type sugar transport system, permease component
FY138_23040	COG1175	transmembrane transport
FY138_23045	COG1653	transport
FY138_23050	COG3842	ATPase activity
FY138_23055	COG2188	Transcriptional regulator
FY138_23065	COG4989	oxidoreductase activity
FY138_23100	COG0438	transferase activity, transferring glycosyl groups
FY138_23105	COG0747	negative chemotaxis
FY138_23110	COG0601	transmembrane transport
FY138_23120	COG3964	amidohydrolase
FY138_23135	COG1921	L-seryl-tRNASec selenium transferase activity
FY138_23140	COG4172	Belongs to the ABC transporter superfamily
FY138_23145	COG0625	glutathione transferase activity
FY138_23160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_23165	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY138_23165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY138_23170	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_23190	COG1312	Catalyzes the dehydration of D-mannonate
FY138_23195	COG1063	alcohol dehydrogenase
FY138_23200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY138_23210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_23215	COG2186	Transcriptional regulator
FY138_23220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY138_23225	COG0850	regulation of cytokinetic process
FY138_23230	COG2894	cell division
FY138_23235	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY138_23240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_23250	COG5001	Diguanylate cyclase
FY138_23265	COG0673	inositol 2-dehydrogenase activity
FY138_23275	COG1653	transport
FY138_23280	COG1175	transmembrane transport
FY138_23285	COG0395	ABC-type sugar transport system, permease component
FY138_23290	COG3842	ATPase activity
FY138_23300	COG0673	inositol 2-dehydrogenase activity
FY138_23330	COG0587	DNA-directed DNA polymerase activity
FY138_23335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY138_23350	COG2186	Transcriptional regulator
FY138_23355	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_23360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_23365	COG1129	ABC transporter
FY138_23370	COG1879	ABC-type sugar transport system periplasmic component
FY138_23375	COG0129	dihydroxy-acid dehydratase activity
FY138_23385	COG0346	lactoylglutathione lyase activity
FY138_23400	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY138_23405	COG4608	Belongs to the ABC transporter superfamily
FY138_23415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_23420	COG0601	transmembrane transport
FY138_23425	COG0747	negative chemotaxis
FY138_23435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY138_23440	COG5001	Diguanylate cyclase
FY138_23450	COG3257	ureidoglycine aminohydrolase activity
FY138_23460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_23465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_23475	COG1129	ABC transporter
FY138_23480	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_23485	COG1879	ABC-type sugar transport system periplasmic component
FY138_23490	COG0583	DNA-binding transcription factor activity
FY138_23515	COG3047	cAMP biosynthetic process
FY138_23525	COG3842	ATPase activity
FY138_23530	COG0395	ABC-type sugar transport system, permease component
FY138_23535	COG1175	transmembrane transport
FY138_23540	COG1653	transport
FY138_23545	COG0523	cobalamin synthesis protein
FY138_23560	COG0523	cobalamin synthesis protein
FY138_23565	COG1121	(ABC) transporter
FY138_23575	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY138_23580	COG0454	-acetyltransferase
FY138_23595	COG0626	cystathionine gamma-synthase activity
FY138_23600	COG2182	Extracellular solute-binding protein
FY138_23610	COG0395	ABC-type sugar transport system, permease component
FY138_23625	COG0395	ABC-type sugar transport system, permease component
FY138_23630	COG1175	transmembrane transport
FY138_23635	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY138_23640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY138_23650	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_23655	COG1063	alcohol dehydrogenase
FY138_23660	COG1609	Transcriptional regulator
FY138_23665	COG2223	nitrite transmembrane transporter activity
FY138_23670	COG4977	sequence-specific DNA binding
FY138_23700	COG0667	Aldo Keto reductase
FY138_23715	COG2186	Transcriptional regulator
FY138_23720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY138_23725	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY138_23730	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_23735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY138_23740	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_23745	COG3618	amidohydrolase
FY138_23755	COG1175	transmembrane transport
FY138_23760	COG0395	ABC-type sugar transport system, permease component
FY138_23765	COG3842	ATPase activity
FY138_23780	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY138_23785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY138_23805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY138_23815	COG1278	Cold shock
FY138_23820	COG0673	inositol 2-dehydrogenase activity
FY138_23835	COG0673	inositol 2-dehydrogenase activity
FY138_23840	COG1309	transcriptional regulator
FY138_23845	COG1653	transport
FY138_23850	COG1175	transmembrane transport
FY138_23855	COG0395	ABC-type sugar transport system, permease component
FY138_23860	COG3842	ATPase activity
FY138_23865	COG1082	Xylose isomerase domain protein TIM barrel
FY138_23880	COG1609	Transcriptional regulator
FY138_23910	COG1175	transmembrane transport
FY138_23915	COG0395	ABC-type sugar transport system, permease component
FY138_23920	COG1116	anion transmembrane transporter activity
FY138_23925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY138_23930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY138_23945	COG3842	ATPase activity
FY138_23950	COG0395	ABC-type sugar transport system, permease component
FY138_23960	COG1653	transport
FY138_23995	COG3842	ATPase activity
FY138_24005	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_24010	COG0395	ABC-type sugar transport system, permease component
FY138_24070	COG2233	PERMEase
FY138_24085	COG5002	protein histidine kinase activity
FY138_24090	COG0745	RESPONSE REGULATOR receiver
FY138_24095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY138_24100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY138_24105	COG0702	epimerase
FY138_24115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY138_24150	COG2235	arginine
FY138_24160	COG0628	permease
FY138_24185	COG1522	sequence-specific DNA binding
FY138_24205	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_24220	COG1414	Transcriptional regulator
FY138_24230	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY138_24260	COG4566	intracellular signal transduction
FY138_24265	COG4566	intracellular signal transduction
FY138_24275	COG0243	molybdopterin cofactor binding
FY138_24280	COG0783	Belongs to the Dps family
FY138_24295	COG0596	Alpha beta hydrolase
FY138_24305	COG1764	response to oxidative stress
FY138_24320	COG0596	Alpha beta hydrolase
FY138_24355	COG4172	Belongs to the ABC transporter superfamily
FY138_24380	COG0601	transmembrane transport
FY138_24385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_24390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY138_24400	COG4106	trans-aconitate 2-methyltransferase activity
FY138_24405	COG0025	NhaP-type Na H and K H
FY138_24410	COG4302	ethanolamine ammonia-lyase activity
FY138_24435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_24440	COG1349	DNA-binding transcription factor activity
FY138_24445	COG4608	Belongs to the ABC transporter superfamily
FY138_24455	COG0601	transmembrane transport
FY138_24460	COG0747	negative chemotaxis
FY138_24465	COG1454	alcohol dehydrogenase
FY138_24470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY138_24475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY138_24480	COG0411	ABC transporter
FY138_24515	COG1192	Involved in chromosome partitioning
FY138_24520	COG1475	DNA binding
FY138_24525	COG0640	Transcriptional regulator
FY138_24540	COG1126	abc transporter atp-binding protein
FY138_24545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY138_24550	COG1609	Transcriptional regulator
FY138_24585	COG3239	Fatty acid desaturase
FY138_24595	COG1278	Cold shock
FY138_24670	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY138_24670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY138_24705	COG4191	Histidine kinase
FY138_24710	COG1132	(ABC) transporter
FY138_24720	COG0640	Transcriptional regulator
FY138_24750	COG4977	sequence-specific DNA binding
FY138_24755	COG2211	Major facilitator Superfamily
FY138_24760	COG2807	transmembrane transport
FY138_24765	COG1846	Transcriptional regulator
FY138_24780	COG2814	Major facilitator Superfamily
FY138_24810	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY138_24825	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY138_24830	COG0583	DNA-binding transcription factor activity
FY138_24845	COG0071	Belongs to the small heat shock protein (HSP20) family
FY138_24890	COG3838	Conjugal transfer protein Trbc
FY138_24895	COG3702	type iv secretory pathway
FY138_24900	COG3451	type IV secretory pathway VirB4
FY138_24915	COG3704	protein secretion by the type IV secretion system
FY138_24925	COG3736	Type IV secretory pathway, component VirB8
FY138_24930	COG3504	Conjugal transfer protein
FY138_24935	COG2948	multi-organism process
FY138_24940	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY138_25040	COG3831	ATPase activity
FY138_25055	COG3505	Type IV secretory pathway VirD4
FY138_25075	COG0583	DNA-binding transcription factor activity
FY138_25115	COG0745	RESPONSE REGULATOR receiver
FY138_25155	COG3842	ATPase activity
FY138_25160	COG4208	sulfate ABC transporter
FY138_25165	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY138_25185	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY138_25190	COG1942	4-Oxalocrotonate Tautomerase
FY138_25200	COG3971	2-oxopent-4-enoate hydratase activity
FY138_25210	COG1414	Transcriptional regulator
FY138_25220	COG1137	ATPase activity
FY138_25235	COG4177	L-phenylalanine transmembrane transporter activity
FY138_25255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY138_25260	COG1175	transmembrane transport
FY138_25265	COG0395	ABC-type sugar transport system, permease component
FY138_25275	COG0366	Alpha amylase catalytic
FY138_25280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY138_25285	COG1082	Xylose isomerase domain protein TIM barrel
FY138_25290	COG3842	ATPase activity
FY138_25300	COG1940	carbohydrate kinase activity
FY138_25305	COG0395	ABC-type sugar transport system, permease component
FY138_25315	COG2182	Extracellular solute-binding protein
FY138_25320	COG0673	inositol 2-dehydrogenase activity
FY138_25350	COG1126	abc transporter atp-binding protein
FY138_25355	COG0765	amino acid transport
FY138_25360	COG0765	amino acid transport
FY138_25370	COG4608	Belongs to the ABC transporter superfamily
FY138_25380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_25395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_25400	COG0583	DNA-binding transcription factor activity
FY138_25405	COG2423	ornithine cyclodeaminase activity
FY138_25415	COG1957	nucleoside hydrolase
FY138_25435	COG1335	isochorismatase
FY138_25440	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_25485	COG0583	DNA-binding transcription factor activity
FY138_25490	COG1902	pentaerythritol trinitrate reductase activity
FY138_25495	COG0583	DNA-binding transcription factor activity
FY138_25500	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_25510	COG1335	isochorismatase
FY138_25515	COG0583	DNA-binding transcription factor activity
FY138_25525	COG1695	Transcriptional regulator
FY138_25605	COG2207	Transcriptional regulator
FY138_25650	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_25665	COG1802	Transcriptional regulator
FY138_25670	COG3485	protocatechuate 3,4-dioxygenase
FY138_25675	COG3971	2-oxopent-4-enoate hydratase activity
FY138_25690	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY138_25695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY138_25710	COG1063	alcohol dehydrogenase
FY138_25720	COG1960	acyl-CoA dehydrogenase activity
FY138_25725	COG1024	Enoyl-CoA hydratase
FY138_25735	COG1012	belongs to the aldehyde dehydrogenase family
FY138_25740	COG0477	Major facilitator Superfamily
FY138_25755	COG3706	GGDEF domain
FY138_25775	COG1846	Transcriptional regulator
FY138_25815	COG1012	belongs to the aldehyde dehydrogenase family
FY138_25825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY138_25835	COG3386	PFAM SMP-30 Gluconolaconase
FY138_25840	COG3622	Belongs to the hyi family
FY138_25845	COG2084	Dehydrogenase
FY138_25870	COG1940	carbohydrate kinase activity
FY138_25875	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY138_25885	COG1129	ABC transporter
FY138_25905	COG0583	DNA-binding transcription factor activity
FY138_25910	COG2271	Major facilitator Superfamily
FY138_25920	COG2272	Belongs to the type-B carboxylesterase lipase family
FY138_25940	COG1129	ABC transporter
FY138_25965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY138_25975	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY138_26010	COG0583	DNA-binding transcription factor activity
FY138_26015	COG1414	Transcriptional regulator
FY138_26025	COG4948	Mandelate Racemase Muconate Lactonizing
FY138_26035	COG3842	ATPase activity
FY138_26040	COG1175	transmembrane transport
FY138_26045	COG0395	ABC-type sugar transport system, permease component
FY138_26055	COG0477	Major facilitator Superfamily
FY138_26090	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY138_26110	COG0747	negative chemotaxis
FY138_26120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_26135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY138_26145	COG4215	(ABC) transporter
FY138_26200	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY138_26205	COG0251	oxidation-reduction process
FY138_26210	COG3547	Transposase (IS116 IS110 IS902 family)
FY138_26245	COG1028	Short-chain dehydrogenase reductase Sdr
FY138_26250	COG1335	isochorismatase
FY138_26260	COG1309	transcriptional regulator
FY138_26265	COG4604	ABC transporter, ATP-binding protein
FY138_26270	COG4605	iron ion homeostasis
FY138_26275	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY138_26285	COG2132	Multicopper oxidase
FY138_26290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY138_26295	COG4771	TonB-dependent receptor
FY138_26330	COG1695	Transcriptional regulator
FY138_26365	COG2132	Multicopper oxidase
FY138_26400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY138_26420	COG1192	Involved in chromosome partitioning
FY138_26425	COG1475	DNA binding
FY138_26430	COG0640	Transcriptional regulator
FY138_26435	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY138_26465	COG2211	Major facilitator Superfamily
FY138_26510	COG4974	Belongs to the 'phage' integrase family
FY138_26515	COG1051	belongs to the nudix hydrolase family
FY138_26555	COG1475	DNA binding
FY138_26580	COG2824	Alkylphosphonate utilization operon protein PhnA
FY138_26600	COG1280	lysine exporter protein (LysE YggA)
FY138_26665	COG5489	Protein of unknown function (DUF736)
FY138_26750	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY138_26765	COG0747	negative chemotaxis
FY138_26785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_26790	COG0584	glycerophosphoryl diester phosphodiesterase
FY138_26795	COG0483	inositol monophosphate 1-phosphatase activity
FY138_26860	COG3161	chorismate lyase activity
FY138_27010	COG3436	PFAM IS66 Orf2 family protein
FY138_27105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY138_27135	COG0583	DNA-binding transcription factor activity
FY138_27140	COG0747	negative chemotaxis
FY138_27155	COG0252	asparaginase activity
FY138_27160	COG0583	DNA-binding transcription factor activity
FY138_27180	COG3842	ATPase activity
FY138_27205	COG3701	Conjugal transfer protein
FY138_27210	COG3846	protein secretion by the type IV secretion system
FY138_27220	COG5314	conjugation
FY138_27225	COG3451	type IV secretory pathway VirB4
FY138_27240	COG4962	Type ii secretion system protein e