locus-tag	class	description
FY139_00025	COG0640	Transcriptional regulator
FY139_00065	COG4178	(ABC) transporter
FY139_00090	COG1082	Xylose isomerase domain protein TIM barrel
FY139_00095	COG0572	uridine kinase
FY139_00105	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_00110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_00115	COG1129	ABC transporter
FY139_00135	COG3284	Transcriptional regulator
FY139_00140	COG1063	alcohol dehydrogenase
FY139_00150	COG0110	maltose O-acetyltransferase activity
FY139_00155	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY139_00180	COG0488	(ABC) transporter
FY139_00185	COG5265	(ABC) transporter
FY139_00190	COG3181	Tripartite tricarboxylate transporter family receptor
FY139_00195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY139_00205	COG3237	CsbD-like
FY139_00225	COG0395	ABC-type sugar transport system, permease component
FY139_00230	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY139_00240	COG0483	inositol monophosphate 1-phosphatase activity
FY139_00250	COG0405	Gamma-glutamyltransferase
FY139_00255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_00260	COG0601	transmembrane transport
FY139_00265	COG0747	negative chemotaxis
FY139_00270	COG2186	Transcriptional regulator
FY139_00280	COG4948	Mandelate Racemase Muconate Lactonizing
FY139_00285	COG4172	Belongs to the ABC transporter superfamily
FY139_00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_00295	COG0601	transmembrane transport
FY139_00300	COG0747	negative chemotaxis
FY139_00305	COG2186	Transcriptional regulator
FY139_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_00320	COG2223	nitrite transmembrane transporter activity
FY139_00330	COG3383	formate dehydrogenase (NAD+) activity
FY139_00350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY139_00365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY139_00375	COG0765	amino acid transport
FY139_00380	COG0765	amino acid transport
FY139_00385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_00400	COG3938	Belongs to the proline racemase family
FY139_00410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_00420	COG0765	amino acid transport
FY139_00435	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY139_00440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_00450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY139_00455	COG0784	Response regulator, receiver
FY139_00470	COG0842	Transport permease protein
FY139_00475	COG0842	Transport permease protein
FY139_00475	COG1129	ABC transporter
FY139_00480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_00485	COG1486	melibiose metabolic process
FY139_00490	COG4172	Belongs to the ABC transporter superfamily
FY139_00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_00500	COG0601	transmembrane transport
FY139_00505	COG0747	negative chemotaxis
FY139_00510	COG1486	melibiose metabolic process
FY139_00535	COG1940	carbohydrate kinase activity
FY139_00540	COG2182	Extracellular solute-binding protein
FY139_00545	COG1175	transmembrane transport
FY139_00550	COG0395	ABC-type sugar transport system, permease component
FY139_00555	COG0165	Argininosuccinate lyase
FY139_00560	COG3842	ATPase activity
FY139_00565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_00570	COG3119	arylsulfatase activity
FY139_00580	COG0583	DNA-binding transcription factor activity
FY139_00585	COG1120	ATPase activity
FY139_00590	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_00595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_00605	COG4774	siderophore transport
FY139_00615	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY139_00630	COG2205	protein histidine kinase activity
FY139_00635	COG0745	RESPONSE REGULATOR receiver
FY139_00640	COG1566	PFAM secretion protein HlyD family protein
FY139_00655	COG1392	Phosphate transport regulator
FY139_00660	COG0306	phosphate transporter
FY139_00665	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY139_00675	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY139_00685	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_00690	COG3300	MHYT domain
FY139_00690	COG5001	Diguanylate cyclase
FY139_00710	COG2186	Transcriptional regulator
FY139_00715	COG0601	transmembrane transport
FY139_00720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_00725	COG0444	Belongs to the ABC transporter superfamily
FY139_00735	COG3842	ATPase activity
FY139_00740	COG0395	ABC-type sugar transport system, permease component
FY139_00755	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY139_00755	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY139_00760	COG1609	Transcriptional regulator
FY139_00770	COG0210	DNA helicase
FY139_00775	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY139_00780	COG1088	dTDP-glucose 4,6-dehydratase activity
FY139_00785	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY139_00790	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY139_00805	COG3754	Rhamnan synthesis protein F
FY139_00810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY139_00830	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY139_00840	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY139_00845	COG1216	Glycosyl transferase, family 2
FY139_00845	COG1442	glycosyl transferase family 8
FY139_00860	COG1132	(ABC) transporter
FY139_00870	COG0583	DNA-binding transcription factor activity
FY139_00875	COG0667	Aldo Keto reductase
FY139_00895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY139_00910	COG0300	oxidoreductase activity
FY139_00915	COG0584	glycerophosphoryl diester phosphodiesterase
FY139_00920	COG1940	carbohydrate kinase activity
FY139_00930	COG3712	iron ion homeostasis
FY139_00935	COG4774	siderophore transport
FY139_00940	COG2814	Major facilitator Superfamily
FY139_00960	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY139_00970	COG3842	ATPase activity
FY139_00975	COG1175	transmembrane transport
FY139_00980	COG0395	ABC-type sugar transport system, permease component
FY139_00985	COG1609	Transcriptional regulator
FY139_00995	COG0673	inositol 2-dehydrogenase activity
FY139_01000	COG1082	Xylose isomerase domain protein TIM barrel
FY139_01015	COG1609	Transcriptional regulator
FY139_01020	COG0183	Belongs to the thiolase family
FY139_01025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY139_01035	COG1414	Transcriptional regulator
FY139_01050	COG0583	DNA-binding transcription factor activity
FY139_01060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY139_01065	COG3485	protocatechuate 3,4-dioxygenase
FY139_01070	COG3485	protocatechuate 3,4-dioxygenase
FY139_01075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY139_01080	COG0765	amino acid transport
FY139_01085	COG0765	amino acid transport
FY139_01090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_01095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_01100	COG1126	abc transporter atp-binding protein
FY139_01105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY139_01110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY139_01135	COG4172	Belongs to the ABC transporter superfamily
FY139_01140	COG0747	negative chemotaxis
FY139_01150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_01165	COG0683	leucine binding
FY139_01180	COG0411	ABC transporter
FY139_01195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_01200	COG3962	Belongs to the TPP enzyme family
FY139_01210	COG3718	enzyme involved in inositol metabolism
FY139_01220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY139_01225	COG1609	Transcriptional regulator
FY139_01230	COG1846	Transcriptional regulator
FY139_01240	COG0523	cobalamin synthesis protein
FY139_01280	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY139_01300	COG0800	Aldolase
FY139_01305	COG2954	triphosphatase activity
FY139_01315	COG1054	Belongs to the UPF0176 family
FY139_01320	COG5001	Diguanylate cyclase
FY139_01320	COG3300	MHYT domain
FY139_01330	COG2011	ABC-type metal ion transport system permease component
FY139_01335	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY139_01340	COG0778	Nitroreductase
FY139_01350	COG2115	Belongs to the xylose isomerase family
FY139_01355	COG1070	Carbohydrate kinase
FY139_01360	COG1609	Transcriptional regulator
FY139_01380	COG1309	transcriptional regulator
FY139_01385	COG1253	flavin adenine dinucleotide binding
FY139_01390	COG0471	metal ion transport
FY139_01390	COG3273	potassium ion transport
FY139_01395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY139_01400	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY139_01405	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY139_01415	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY139_01420	COG1121	(ABC) transporter
FY139_01425	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY139_01430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY139_01440	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_01445	COG1414	Transcriptional regulator
FY139_01450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY139_01470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY139_01520	COG0395	ABC-type sugar transport system, permease component
FY139_01525	COG1175	transmembrane transport
FY139_01535	COG2390	Transcriptional regulator
FY139_01540	COG4172	Belongs to the ABC transporter superfamily
FY139_01545	COG1473	amidohydrolase
FY139_01555	COG0601	transmembrane transport
FY139_01560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_01570	COG0693	protein deglycase activity
FY139_01575	COG0154	amidase activity
FY139_01580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_01590	COG0747	negative chemotaxis
FY139_01595	COG0583	DNA-binding transcription factor activity
FY139_01600	COG4608	Belongs to the ABC transporter superfamily
FY139_01605	COG0444	Belongs to the ABC transporter superfamily
FY139_01610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_01615	COG0601	transmembrane transport
FY139_01620	COG0747	negative chemotaxis
FY139_01635	COG1473	amidohydrolase
FY139_01640	COG2814	Major facilitator Superfamily
FY139_01645	COG0583	DNA-binding transcription factor activity
FY139_01650	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY139_01660	COG3842	ATPase activity
FY139_01670	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY139_01680	COG1609	Transcriptional regulator
FY139_01685	COG0583	DNA-binding transcription factor activity
FY139_01690	COG1960	acyl-CoA dehydrogenase activity
FY139_01695	COG4774	siderophore transport
FY139_01695	COG1629	transport
FY139_01705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_01715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_01720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_01730	COG2375	cellular response to nickel ion
FY139_01740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY139_01745	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY139_01745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY139_01755	COG1169	isochorismate synthase
FY139_01760	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY139_01765	COG1535	isochorismatase
FY139_01765	COG3433	isochorismatase activity
FY139_01770	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_01785	COG3005	denitrification pathway
FY139_01795	COG0243	molybdopterin cofactor binding
FY139_01810	COG4459	periplasmic nitrate reductase
FY139_01845	COG0826	peptidase U32
FY139_01855	COG3189	MarR family transcriptional regulator
FY139_01860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY139_01890	COG3256	nitric oxide reductase
FY139_01895	COG0714	Associated with various cellular activities
FY139_01955	COG0673	inositol 2-dehydrogenase activity
FY139_01965	COG1609	Transcriptional regulator
FY139_01970	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_01975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_01980	COG1129	ABC transporter
FY139_01985	COG1879	ABC-type sugar transport system periplasmic component
FY139_01995	COG0583	DNA-binding transcription factor activity
FY139_02010	COG1609	Transcriptional regulator
FY139_02015	COG0673	inositol 2-dehydrogenase activity
FY139_02025	COG1653	transport
FY139_02030	COG1175	transmembrane transport
FY139_02035	COG0395	ABC-type sugar transport system, permease component
FY139_02040	COG3842	ATPase activity
FY139_02055	COG1253	flavin adenine dinucleotide binding
FY139_02080	COG3300	MHYT domain
FY139_02080	COG5001	Diguanylate cyclase
FY139_02210	COG0477	Major facilitator Superfamily
FY139_02230	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_02240	COG1879	ABC-type sugar transport system periplasmic component
FY139_02250	COG1063	alcohol dehydrogenase
FY139_02265	COG1136	(ABC) transporter
FY139_02280	COG1309	transcriptional regulator
FY139_02300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY139_02310	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY139_02310	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY139_02320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_02325	COG0047	phosphoribosylformylglycinamidine synthase activity
FY139_02335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_02340	COG1012	belongs to the aldehyde dehydrogenase family
FY139_02345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_02355	COG3448	diguanylate cyclase activity
FY139_02355	COG4175	Glycine betaine
FY139_02365	COG4176	ABC-type proline glycine betaine transport system permease component
FY139_02370	COG3938	Belongs to the proline racemase family
FY139_02375	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY139_02410	COG1733	regulation of RNA biosynthetic process
FY139_02460	COG0477	Major facilitator Superfamily
FY139_02470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY139_02475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY139_02490	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_02500	COG0395	ABC-type sugar transport system, permease component
FY139_02525	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_02530	COG1349	DNA-binding transcription factor activity
FY139_02535	COG1069	ribulokinase activity
FY139_02555	COG1940	carbohydrate kinase activity
FY139_02570	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY139_02575	COG1177	transmembrane transport
FY139_02585	COG3842	ATPase activity
FY139_02640	COG1136	(ABC) transporter
FY139_02640	COG0577	efflux transmembrane transporter activity
FY139_02665	COG1845	cytochrome c oxidase, subunit III
FY139_02670	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY139_02675	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY139_02680	COG3474	cytochrome
FY139_02710	COG3842	ATPase activity
FY139_02715	COG0395	ABC-type sugar transport system, permease component
FY139_02720	COG1175	transmembrane transport
FY139_02725	COG1653	transport
FY139_02730	COG1012	belongs to the aldehyde dehydrogenase family
FY139_02735	COG1024	Enoyl-CoA hydratase
FY139_02755	COG4702	Belongs to the UPF0303 family
FY139_02760	COG1629	transport
FY139_02760	COG4774	siderophore transport
FY139_02765	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY139_02770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_02775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_02780	COG1120	ATPase activity
FY139_02795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY139_02805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY139_02810	COG1177	transmembrane transport
FY139_02815	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY139_02820	COG3842	ATPase activity
FY139_02845	COG1335	isochorismatase
FY139_02860	COG0583	DNA-binding transcription factor activity
FY139_02865	COG2318	DinB family
FY139_02890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY139_02920	COG0778	Nitroreductase
FY139_02940	COG0277	FAD linked oxidase domain protein
FY139_02960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_02965	COG4172	Belongs to the ABC transporter superfamily
FY139_02975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_02985	COG0431	NADPH-dependent FMN reductase
FY139_03005	COG1522	sequence-specific DNA binding
FY139_03010	COG2376	Dihydroxyacetone kinase
FY139_03020	COG4221	oxidoreductase activity
FY139_03025	COG0625	glutathione transferase activity
FY139_03035	COG1566	PFAM secretion protein HlyD family protein
FY139_03045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY139_03050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY139_03065	COG0534	Mate efflux family protein
FY139_03100	COG1733	regulation of RNA biosynthetic process
FY139_03110	COG1136	(ABC) transporter
FY139_03110	COG0577	efflux transmembrane transporter activity
FY139_03115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_03125	COG0745	RESPONSE REGULATOR receiver
FY139_03145	COG3209	COG3209 Rhs family protein
FY139_03175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_03200	COG3177	Filamentation induced by cAMP protein fic
FY139_03215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_03220	COG4597	amino acid ABC transporter
FY139_03225	COG0765	amino acid transport
FY139_03250	COG0747	negative chemotaxis
FY139_03255	COG0601	transmembrane transport
FY139_03260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_03265	COG0444	Belongs to the ABC transporter superfamily
FY139_03270	COG4608	Belongs to the ABC transporter superfamily
FY139_03290	COG4213	ABC transporter substrate-binding protein
FY139_03295	COG1129	ABC transporter
FY139_03300	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_03315	COG0667	Aldo Keto reductase
FY139_03340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_03345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_03350	COG1129	ABC transporter
FY139_03360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_03370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_03380	COG0747	negative chemotaxis
FY139_03385	COG0747	negative chemotaxis
FY139_03390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_03400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_03405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_03410	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY139_03420	COG0405	Gamma-glutamyltransferase
FY139_03450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_03455	COG0436	Aminotransferase
FY139_03470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_03475	COG0765	amino acid transport
FY139_03485	COG1126	abc transporter atp-binding protein
FY139_03495	COG2186	Transcriptional regulator
FY139_03515	COG1846	Transcriptional regulator
FY139_03520	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_03530	COG0583	DNA-binding transcription factor activity
FY139_03565	COG0583	DNA-binding transcription factor activity
FY139_03585	COG1280	lysine exporter protein (LysE YggA)
FY139_03590	COG3920	Histidine kinase
FY139_03615	COG0753	catalase activity
FY139_03635	COG1278	Cold shock
FY139_03675	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_03680	COG1902	pentaerythritol trinitrate reductase activity
FY139_03685	COG4221	oxidoreductase activity
FY139_03690	COG1309	transcriptional regulator
FY139_03705	COG1280	lysine exporter protein (LysE YggA)
FY139_03715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY139_03760	COG1196	nuclear chromosome segregation
FY139_03760	COG0739	heme binding
FY139_03760	COG0741	lytic transglycosylase activity
FY139_03765	COG0542	response to heat
FY139_03775	COG2890	protein-(glutamine-N5) methyltransferase activity
FY139_03780	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY139_03790	COG0527	aspartate kinase activity
FY139_03805	COG0019	diaminopimelate decarboxylase activity
FY139_03820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY139_03840	COG0784	Response regulator, receiver
FY139_03855	COG1522	sequence-specific DNA binding
FY139_03865	COG1116	anion transmembrane transporter activity
FY139_03870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_03875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY139_03880	COG1012	belongs to the aldehyde dehydrogenase family
FY139_03885	COG0583	DNA-binding transcription factor activity
FY139_03890	COG0435	Glutathione S-transferase
FY139_03905	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY139_03910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY139_03915	COG0189	ligase activity
FY139_03935	COG0693	protein deglycase activity
FY139_03965	COG3685	Protein conserved in bacteria
FY139_03970	COG4993	Dehydrogenase
FY139_03985	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_03990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY139_04035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_04050	COG0246	Mannitol dehydrogenase
FY139_04055	COG4608	Belongs to the ABC transporter superfamily
FY139_04060	COG0444	Belongs to the ABC transporter superfamily
FY139_04065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_04070	COG0601	transmembrane transport
FY139_04075	COG0747	negative chemotaxis
FY139_04085	COG4221	oxidoreductase activity
FY139_04115	COG0539	negative regulation of cytoplasmic translation
FY139_04120	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY139_04150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY139_04155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY139_04185	COG1294	oxidase, subunit
FY139_04195	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY139_04200	COG4988	ABC transporter
FY139_04210	COG1063	alcohol dehydrogenase
FY139_04215	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_04220	COG2084	Dehydrogenase
FY139_04230	COG1522	sequence-specific DNA binding
FY139_04235	COG1794	racemase activity, acting on amino acids and derivatives
FY139_04250	COG0058	SHG alpha-glucan phosphorylase activity
FY139_04255	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY139_04260	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY139_04265	COG0297	glycogen (starch) synthase activity
FY139_04270	COG0033	Phosphoglucomutase
FY139_04275	COG1523	belongs to the glycosyl hydrolase 13 family
FY139_04305	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY139_04305	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY139_04320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_04325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY139_04345	COG1215	transferase activity, transferring glycosyl groups
FY139_04350	COG2327	Polysaccharide pyruvyl transferase
FY139_04355	COG0463	Glycosyl transferase, family 2
FY139_04360	COG2244	polysaccharide biosynthetic process
FY139_04365	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY139_04370	COG2273	Hydrolase Family 16
FY139_04375	COG0438	transferase activity, transferring glycosyl groups
FY139_04380	COG1215	transferase activity, transferring glycosyl groups
FY139_04385	COG1215	transferase activity, transferring glycosyl groups
FY139_04390	COG1215	transferase activity, transferring glycosyl groups
FY139_04395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY139_04400	COG0489	protein tyrosine kinase activity
FY139_04400	COG3206	protein involved in exopolysaccharide biosynthesis
FY139_04405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY139_04410	COG0784	Response regulator, receiver
FY139_04410	COG4191	Histidine kinase
FY139_04425	COG4176	ABC-type proline glycine betaine transport system permease component
FY139_04430	COG4175	Glycine betaine
FY139_04430	COG3448	diguanylate cyclase activity
FY139_04445	COG0564	pseudouridine synthase activity
FY139_04450	COG0500	methyltransferase
FY139_04460	COG2133	pyrroloquinoline quinone binding
FY139_04470	COG2197	response regulator
FY139_04475	COG4585	Histidine kinase
FY139_04480	COG1879	ABC-type sugar transport system periplasmic component
FY139_04485	COG1129	ABC transporter
FY139_04490	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_04500	COG3386	PFAM SMP-30 Gluconolaconase
FY139_04505	COG2137	regulation of response to DNA damage stimulus
FY139_04510	COG3474	cytochrome
FY139_04520	COG1120	ATPase activity
FY139_04535	COG4774	siderophore transport
FY139_04540	COG0583	DNA-binding transcription factor activity
FY139_04550	COG2194	sulfuric ester hydrolase activity
FY139_04565	COG0477	Major facilitator Superfamily
FY139_04590	COG0673	inositol 2-dehydrogenase activity
FY139_04595	COG0697	spore germination
FY139_04605	COG0010	Belongs to the arginase family
FY139_04620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY139_04625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY139_04630	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY139_04635	COG0156	8-amino-7-oxononanoate synthase activity
FY139_04640	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY139_04690	COG0671	phosphoesterase, PA-phosphatase related
FY139_04695	COG0745	RESPONSE REGULATOR receiver
FY139_04700	COG2205	protein histidine kinase activity
FY139_04710	COG0477	Major facilitator Superfamily
FY139_04715	COG0583	DNA-binding transcription factor activity
FY139_04735	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY139_04750	COG0346	lactoylglutathione lyase activity
FY139_04755	COG0583	DNA-binding transcription factor activity
FY139_04785	COG1215	transferase activity, transferring glycosyl groups
FY139_04805	COG0840	transmembrane signaling receptor activity
FY139_04820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_04835	COG2828	Protein conserved in bacteria
FY139_04840	COG0583	DNA-binding transcription factor activity
FY139_04845	COG1846	Transcriptional regulator
FY139_04870	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_04875	COG1309	transcriptional regulator
FY139_04880	COG2207	Transcriptional regulator
FY139_04895	COG1566	PFAM secretion protein HlyD family protein
FY139_04915	COG0395	ABC-type sugar transport system, permease component
FY139_04920	COG4166	transmembrane transport
FY139_04925	COG0601	transmembrane transport
FY139_04930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_04935	COG4172	Belongs to the ABC transporter superfamily
FY139_04975	COG0402	S-adenosylhomocysteine deaminase activity
FY139_04980	COG1228	amidohydrolase
FY139_04985	COG2986	histidine ammonia-lyase
FY139_04995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY139_05025	COG1192	Involved in chromosome partitioning
FY139_05030	COG1475	DNA binding
FY139_05035	COG1414	Transcriptional regulator
FY139_05055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY139_05060	COG4771	TonB-dependent receptor
FY139_05070	COG0366	Alpha amylase catalytic
FY139_05075	COG4770	biotin carboxylase activity
FY139_05080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY139_05085	COG4336	lyase activity
FY139_05090	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY139_05095	COG1914	H( )-stimulated, divalent metal cation uptake system
FY139_05100	COG1802	Transcriptional regulator
FY139_05105	COG3707	response regulator
FY139_05115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY139_05120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_05125	COG1116	anion transmembrane transporter activity
FY139_05130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY139_05140	COG0243	molybdopterin cofactor binding
FY139_05145	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY139_05145	COG1648	precorrin-2 dehydrogenase activity
FY139_05160	COG3842	ATPase activity
FY139_05175	COG0395	ABC-type sugar transport system, permease component
FY139_05190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY139_05205	COG0071	Belongs to the small heat shock protein (HSP20) family
FY139_05250	COG1879	ABC-type sugar transport system periplasmic component
FY139_05255	COG1129	ABC transporter
FY139_05260	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_05270	COG0667	Aldo Keto reductase
FY139_05275	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY139_05280	COG1830	Aldolase
FY139_05285	COG1070	Carbohydrate kinase
FY139_05290	COG0840	transmembrane signaling receptor activity
FY139_05305	COG0436	Aminotransferase
FY139_05315	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY139_05325	COG3842	ATPase activity
FY139_05330	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY139_05335	COG1984	allophanate hydrolase subunit 2
FY139_05340	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY139_05350	COG0439	Biotin carboxylase
FY139_05355	COG0511	ligase activity, forming carbon-carbon bonds
FY139_05360	COG0697	spore germination
FY139_05365	COG0697	spore germination
FY139_05380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY139_05395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY139_05400	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_05405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY139_05410	COG4221	oxidoreductase activity
FY139_05415	COG0765	amino acid transport
FY139_05420	COG0765	amino acid transport
FY139_05430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_05435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY139_05440	COG1063	alcohol dehydrogenase
FY139_05455	COG1304	FMN binding
FY139_05480	COG3842	ATPase activity
FY139_05490	COG0395	ABC-type sugar transport system, permease component
FY139_05495	COG1175	transmembrane transport
FY139_05510	COG2186	Transcriptional regulator
FY139_05515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY139_05520	COG0488	(ABC) transporter
FY139_05535	COG2308	Evidence 4 Homologs of previously reported genes of
FY139_05535	COG2307	Protein conserved in bacteria
FY139_05575	COG1454	alcohol dehydrogenase
FY139_05580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY139_05590	COG0747	negative chemotaxis
FY139_05595	COG0601	transmembrane transport
FY139_05600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_05610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_05655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY139_05680	COG1082	Xylose isomerase domain protein TIM barrel
FY139_05685	COG0673	inositol 2-dehydrogenase activity
FY139_05690	COG1082	Xylose isomerase domain protein TIM barrel
FY139_05710	COG1609	Transcriptional regulator
FY139_05715	COG2986	histidine ammonia-lyase
FY139_05720	COG4175	Glycine betaine
FY139_05720	COG0517	IMP dehydrogenase activity
FY139_05725	COG4176	ABC-type proline glycine betaine transport system permease component
FY139_05765	COG2186	Transcriptional regulator
FY139_05770	COG1027	Aspartate ammonia-lyase
FY139_05780	COG0252	asparaginase activity
FY139_05790	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY139_05795	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY139_05800	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY139_05805	COG2205	protein histidine kinase activity
FY139_05820	COG0067	glutamate synthase
FY139_05820	COG0069	glutamate synthase activity
FY139_05820	COG0070	glutamate synthase
FY139_05835	COG2205	protein histidine kinase activity
FY139_05850	COG2951	lytic endotransglycosylase activity
FY139_05855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY139_05880	COG0330	HflC and HflK could
FY139_05885	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY139_05890	COG0737	Belongs to the 5'-nucleotidase family
FY139_05900	COG5310	Homospermidine synthase
FY139_05910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY139_05915	COG1164	Oligoendopeptidase f
FY139_05920	COG2204	response regulator
FY139_05925	COG3108	Peptidase M15
FY139_05930	COG0469	pyruvate kinase activity
FY139_05950	COG3750	Belongs to the UPF0335 family
FY139_05955	COG0457	Tetratricopeptide repeat
FY139_05960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY139_05965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY139_05970	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY139_06000	COG0483	inositol monophosphate 1-phosphatase activity
FY139_06020	COG1132	(ABC) transporter
FY139_06025	COG0254	rRNA binding
FY139_06045	COG3588	fructose-bisphosphate aldolase
FY139_06050	COG0126	phosphoglycerate kinase activity
FY139_06090	COG1253	flavin adenine dinucleotide binding
FY139_06100	COG1692	metallophosphoesterase
FY139_06115	COG0217	transcriptional regulatory protein
FY139_06120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_06125	COG0840	transmembrane signaling receptor activity
FY139_06130	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY139_06135	COG0632	four-way junction helicase activity
FY139_06140	COG2255	four-way junction helicase activity
FY139_06155	COG0494	nUDIX hydrolase
FY139_06165	COG0824	Thioesterase
FY139_06185	COG0823	Involved in the tonB-independent uptake of proteins
FY139_06190	COG2885	chlorophyll binding
FY139_06200	COG0037	tRNA processing
FY139_06205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY139_06210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY139_06225	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY139_06240	COG0482	sulfurtransferase activity
FY139_06270	COG2835	tetraacyldisaccharide 4'-kinase activity
FY139_06275	COG2373	Large extracellular alpha-helical protein
FY139_06280	COG4953	penicillin-binding protein 1C
FY139_06290	COG1473	amidohydrolase
FY139_06295	COG1686	Belongs to the peptidase S11 family
FY139_06300	COG0523	cobalamin synthesis protein
FY139_06305	COG0425	Belongs to the sulfur carrier protein TusA family
FY139_06305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY139_06310	COG3034	peptidoglycan biosynthetic process
FY139_06315	COG0825	malonyl-CoA metabolic process
FY139_06320	COG4974	Belongs to the 'phage' integrase family
FY139_06330	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY139_06335	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY139_06375	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY139_06380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY139_06400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY139_06405	COG2226	methyltransferase
FY139_06410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY139_06415	COG0287	Prephenate dehydrogenase
FY139_06425	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY139_06445	COG2884	Cell division ATP-binding protein ftsE
FY139_06480	COG0165	Argininosuccinate lyase
FY139_06485	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY139_06495	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY139_06505	COG2086	electron transfer activity
FY139_06515	COG2096	Adenosyltransferase
FY139_06525	COG0300	oxidoreductase activity
FY139_06535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY139_06545	COG3800	Transcriptional regulator
FY139_06545	COG1396	sequence-specific DNA binding
FY139_06550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY139_06555	COG0625	glutathione transferase activity
FY139_06570	COG4770	biotin carboxylase activity
FY139_06575	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY139_06575	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY139_06580	COG0346	lactoylglutathione lyase activity
FY139_06595	COG4213	ABC transporter substrate-binding protein
FY139_06600	COG4214	carbohydrate transport
FY139_06605	COG1129	ABC transporter
FY139_06610	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY139_06620	COG1396	sequence-specific DNA binding
FY139_06675	COG3833	ABC-type maltose transport systems, permease component
FY139_06680	COG3842	ATPase activity
FY139_06695	COG2273	Hydrolase Family 16
FY139_06695	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY139_06700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY139_06715	COG0438	transferase activity, transferring glycosyl groups
FY139_06720	COG0438	transferase activity, transferring glycosyl groups
FY139_06740	COG0489	protein tyrosine kinase activity
FY139_06740	COG3206	protein involved in exopolysaccharide biosynthesis
FY139_06750	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY139_06765	COG2244	polysaccharide biosynthetic process
FY139_06830	COG0697	spore germination
FY139_06835	COG0653	protein targeting
FY139_06840	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY139_06845	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY139_06855	COG0494	nUDIX hydrolase
FY139_06870	COG2226	methyltransferase
FY139_06875	COG1040	competence protein
FY139_06885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY139_06895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY139_06910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY139_06915	COG4150	thiosulfate binding
FY139_06925	COG4208	sulfate ABC transporter
FY139_06930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY139_06935	COG4335	DNA alkylation repair
FY139_06950	COG5001	Diguanylate cyclase
FY139_06955	COG2264	protein methyltransferase activity
FY139_06970	COG3254	rhamnose metabolic process
FY139_06975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_06980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_06985	COG1129	ABC transporter
FY139_06995	COG1349	DNA-binding transcription factor activity
FY139_07000	COG3347	Dehydrogenase
FY139_07000	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_07005	COG4952	isomerase
FY139_07010	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY139_07015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY139_07035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY139_07040	COG1960	acyl-CoA dehydrogenase activity
FY139_07050	COG0183	Belongs to the thiolase family
FY139_07055	COG1960	acyl-CoA dehydrogenase activity
FY139_07065	COG0022	dehydrogenase e1 component
FY139_07075	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY139_07080	COG2391	methyltransferase activity
FY139_07090	COG0640	Transcriptional regulator
FY139_07095	COG3453	Protein conserved in bacteria
FY139_07095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY139_07105	COG0300	oxidoreductase activity
FY139_07120	COG2186	Transcriptional regulator
FY139_07130	COG0601	transmembrane transport
FY139_07140	COG0444	Belongs to the ABC transporter superfamily
FY139_07145	COG4608	Belongs to the ABC transporter superfamily
FY139_07275	COG2369	cell adhesion
FY139_07280	COG4383	Mu-like prophage protein gp29
FY139_07285	COG4373	Mu-like prophage FluMu protein gp28
FY139_07420	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_07425	COG1733	regulation of RNA biosynthetic process
FY139_07435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07460	COG1473	amidohydrolase
FY139_07465	COG0747	negative chemotaxis
FY139_07480	COG4166	transmembrane transport
FY139_07485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07490	COG0583	DNA-binding transcription factor activity
FY139_07500	COG0667	Aldo Keto reductase
FY139_07510	COG0444	Belongs to the ABC transporter superfamily
FY139_07525	COG0747	negative chemotaxis
FY139_07535	COG1960	acyl-CoA dehydrogenase activity
FY139_07565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY139_07580	COG1959	2 iron, 2 sulfur cluster binding
FY139_07585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_07595	COG1473	amidohydrolase
FY139_07605	COG1126	abc transporter atp-binding protein
FY139_07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_07620	COG0583	DNA-binding transcription factor activity
FY139_07635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_07645	COG1522	sequence-specific DNA binding
FY139_07650	COG4172	Belongs to the ABC transporter superfamily
FY139_07655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_07690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_07695	COG1012	belongs to the aldehyde dehydrogenase family
FY139_07700	COG0473	3-isopropylmalate dehydrogenase activity
FY139_07705	COG1012	belongs to the aldehyde dehydrogenase family
FY139_07750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_07755	COG1120	ATPase activity
FY139_07765	COG2226	methyltransferase
FY139_07780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_07785	COG1120	ATPase activity
FY139_07790	COG1595	DNA-templated transcription, initiation
FY139_07810	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY139_07815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_07835	COG0673	inositol 2-dehydrogenase activity
FY139_07840	COG0673	inositol 2-dehydrogenase activity
FY139_07850	COG1175	transmembrane transport
FY139_07855	COG0395	ABC-type sugar transport system, permease component
FY139_07860	COG3842	ATPase activity
FY139_07870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY139_07875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY139_07880	COG2197	response regulator
FY139_07885	COG0601	transmembrane transport
FY139_07890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_07910	COG0747	negative chemotaxis
FY139_07925	COG1446	asparaginase
FY139_07930	COG0583	DNA-binding transcription factor activity
FY139_07935	COG0601	transmembrane transport
FY139_07940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_07955	COG0747	negative chemotaxis
FY139_07960	COG1473	amidohydrolase
FY139_07975	COG1129	ABC transporter
FY139_07980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_07985	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY139_07990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY139_08000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY139_08015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_08025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_08030	COG2079	MmgE PrpD family protein
FY139_08035	COG1126	abc transporter atp-binding protein
FY139_08040	COG0765	amino acid transport
FY139_08055	COG0281	malic enzyme
FY139_08055	COG0280	phosphate acetyltransferase
FY139_08060	COG0583	DNA-binding transcription factor activity
FY139_08085	COG1175	transmembrane transport
FY139_08090	COG0395	ABC-type sugar transport system, permease component
FY139_08105	COG0673	inositol 2-dehydrogenase activity
FY139_08110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY139_08115	COG0720	synthase
FY139_08120	COG0602	queuosine metabolic process
FY139_08125	COG0673	inositol 2-dehydrogenase activity
FY139_08135	COG3842	ATPase activity
FY139_08150	COG1653	transport
FY139_08155	COG1609	Transcriptional regulator
FY139_08170	COG2094	Belongs to the DNA glycosylase MPG family
FY139_08180	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_08190	COG1376	ErfK ybiS ycfS ynhG family protein
FY139_08195	COG0840	transmembrane signaling receptor activity
FY139_08200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY139_08210	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY139_08215	COG1596	polysaccharide export
FY139_08220	COG3307	-O-antigen
FY139_08250	COG2197	response regulator
FY139_08260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY139_08285	COG2942	2-epimerase
FY139_08295	COG1215	transferase activity, transferring glycosyl groups
FY139_08315	COG1473	amidohydrolase
FY139_08325	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_08330	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY139_08335	COG1301	dicarboxylic acid transport
FY139_08340	COG4191	Histidine kinase
FY139_08345	COG2204	response regulator
FY139_08360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_08365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY139_08370	COG1522	sequence-specific DNA binding
FY139_08375	COG0351	phosphomethylpyrimidine kinase
FY139_08380	COG0352	thiamine-phosphate diphosphorylase activity
FY139_08385	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY139_08390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY139_08395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_08405	COG1501	Belongs to the glycosyl hydrolase 31 family
FY139_08410	COG0395	ABC-type sugar transport system, permease component
FY139_08415	COG1175	transmembrane transport
FY139_08420	COG1653	transport
FY139_08425	COG3842	ATPase activity
FY139_08430	COG2188	Transcriptional regulator
FY139_08440	COG4989	oxidoreductase activity
FY139_08475	COG0438	transferase activity, transferring glycosyl groups
FY139_08480	COG0747	negative chemotaxis
FY139_08485	COG0601	transmembrane transport
FY139_08495	COG3964	amidohydrolase
FY139_08510	COG1921	L-seryl-tRNASec selenium transferase activity
FY139_08515	COG4172	Belongs to the ABC transporter superfamily
FY139_08520	COG0625	glutathione transferase activity
FY139_08535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_08540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY139_08540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY139_08545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY139_08565	COG1312	Catalyzes the dehydration of D-mannonate
FY139_08570	COG1063	alcohol dehydrogenase
FY139_08575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY139_08585	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY139_08590	COG2186	Transcriptional regulator
FY139_08595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY139_08600	COG0850	regulation of cytokinetic process
FY139_08605	COG2894	cell division
FY139_08610	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY139_08615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_08625	COG5001	Diguanylate cyclase
FY139_08640	COG0673	inositol 2-dehydrogenase activity
FY139_08650	COG1653	transport
FY139_08655	COG1175	transmembrane transport
FY139_08660	COG0395	ABC-type sugar transport system, permease component
FY139_08665	COG3842	ATPase activity
FY139_08675	COG0673	inositol 2-dehydrogenase activity
FY139_08705	COG0587	DNA-directed DNA polymerase activity
FY139_08710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY139_08725	COG2186	Transcriptional regulator
FY139_08730	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_08735	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_08740	COG1129	ABC transporter
FY139_08745	COG1879	ABC-type sugar transport system periplasmic component
FY139_08750	COG0129	dihydroxy-acid dehydratase activity
FY139_08760	COG0346	lactoylglutathione lyase activity
FY139_08775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY139_08780	COG4608	Belongs to the ABC transporter superfamily
FY139_08790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_08795	COG0601	transmembrane transport
FY139_08800	COG0747	negative chemotaxis
FY139_08810	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY139_08815	COG5001	Diguanylate cyclase
FY139_08825	COG3257	ureidoglycine aminohydrolase activity
FY139_08835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_08840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY139_08850	COG1129	ABC transporter
FY139_08855	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_08860	COG1879	ABC-type sugar transport system periplasmic component
FY139_08865	COG0583	DNA-binding transcription factor activity
FY139_08890	COG3047	cAMP biosynthetic process
FY139_08900	COG3842	ATPase activity
FY139_08905	COG0395	ABC-type sugar transport system, permease component
FY139_08910	COG1175	transmembrane transport
FY139_08915	COG1653	transport
FY139_08920	COG0523	cobalamin synthesis protein
FY139_08935	COG0523	cobalamin synthesis protein
FY139_08940	COG1121	(ABC) transporter
FY139_08950	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY139_08955	COG0454	-acetyltransferase
FY139_08970	COG0626	cystathionine gamma-synthase activity
FY139_08975	COG2182	Extracellular solute-binding protein
FY139_08985	COG0395	ABC-type sugar transport system, permease component
FY139_09000	COG0395	ABC-type sugar transport system, permease component
FY139_09005	COG1175	transmembrane transport
FY139_09010	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY139_09015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_09025	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_09030	COG1063	alcohol dehydrogenase
FY139_09035	COG1609	Transcriptional regulator
FY139_09040	COG2223	nitrite transmembrane transporter activity
FY139_09045	COG4977	sequence-specific DNA binding
FY139_09075	COG0667	Aldo Keto reductase
FY139_09090	COG2186	Transcriptional regulator
FY139_09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY139_09100	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY139_09105	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_09110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_09115	COG4948	Mandelate Racemase Muconate Lactonizing
FY139_09120	COG3618	amidohydrolase
FY139_09130	COG1175	transmembrane transport
FY139_09135	COG0395	ABC-type sugar transport system, permease component
FY139_09140	COG3842	ATPase activity
FY139_09155	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY139_09160	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY139_09180	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY139_09190	COG1278	Cold shock
FY139_09195	COG0673	inositol 2-dehydrogenase activity
FY139_09210	COG0673	inositol 2-dehydrogenase activity
FY139_09215	COG1309	transcriptional regulator
FY139_09220	COG1653	transport
FY139_09225	COG1175	transmembrane transport
FY139_09230	COG0395	ABC-type sugar transport system, permease component
FY139_09235	COG3842	ATPase activity
FY139_09240	COG1082	Xylose isomerase domain protein TIM barrel
FY139_09255	COG1609	Transcriptional regulator
FY139_09285	COG1175	transmembrane transport
FY139_09290	COG0395	ABC-type sugar transport system, permease component
FY139_09295	COG1116	anion transmembrane transporter activity
FY139_09300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_09305	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY139_09320	COG3842	ATPase activity
FY139_09325	COG0395	ABC-type sugar transport system, permease component
FY139_09335	COG1653	transport
FY139_09370	COG3842	ATPase activity
FY139_09380	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY139_09385	COG0395	ABC-type sugar transport system, permease component
FY139_09445	COG2233	PERMEase
FY139_09460	COG5002	protein histidine kinase activity
FY139_09465	COG0745	RESPONSE REGULATOR receiver
FY139_09470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_09475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY139_09480	COG0702	epimerase
FY139_09490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY139_09525	COG2235	arginine
FY139_09535	COG0628	permease
FY139_09560	COG1522	sequence-specific DNA binding
FY139_09580	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_09595	COG1414	Transcriptional regulator
FY139_09605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY139_09635	COG4566	intracellular signal transduction
FY139_09640	COG4566	intracellular signal transduction
FY139_09650	COG0243	molybdopterin cofactor binding
FY139_09655	COG0783	Belongs to the Dps family
FY139_09670	COG0596	Alpha beta hydrolase
FY139_09680	COG1764	response to oxidative stress
FY139_09695	COG0596	Alpha beta hydrolase
FY139_09730	COG4172	Belongs to the ABC transporter superfamily
FY139_09755	COG0601	transmembrane transport
FY139_09760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_09765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_09775	COG4106	trans-aconitate 2-methyltransferase activity
FY139_09780	COG0025	NhaP-type Na H and K H
FY139_09785	COG4302	ethanolamine ammonia-lyase activity
FY139_09810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY139_09815	COG1349	DNA-binding transcription factor activity
FY139_09820	COG4608	Belongs to the ABC transporter superfamily
FY139_09830	COG0601	transmembrane transport
FY139_09835	COG0747	negative chemotaxis
FY139_09840	COG1454	alcohol dehydrogenase
FY139_09845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY139_09850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY139_09855	COG0411	ABC transporter
FY139_09890	COG1278	Cold shock
FY139_09920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY139_09930	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY139_09935	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY139_09940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY139_09945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY139_09950	COG1420	regulation of RNA biosynthetic process
FY139_09955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY139_09960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY139_09965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY139_09975	COG1137	ATPase activity
FY139_09980	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY139_09990	COG0616	signal peptide processing
FY139_09995	COG0776	regulation of translation
FY139_10005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY139_10010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY139_10015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY139_10030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY139_10035	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY139_10040	COG0728	peptidoglycan biosynthetic process
FY139_10050	COG0180	Tryptophanyl-tRNA synthetase
FY139_10060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY139_10065	COG1214	PFAM Peptidase M22, glycoprotease
FY139_10085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY139_10090	COG1702	phosphate starvation-inducible protein PhoH
FY139_10095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY139_10105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY139_10110	COG1396	sequence-specific DNA binding
FY139_10115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY139_10120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY139_10125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_10135	COG0242	peptide deformylase activity
FY139_10140	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY139_10145	COG0101	tRNA pseudouridine synthase activity
FY139_10155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY139_10160	COG2171	N-acyltransferase activity
FY139_10170	COG0840	transmembrane signaling receptor activity
FY139_10175	COG1957	nucleoside hydrolase
FY139_10180	COG0071	Belongs to the small heat shock protein (HSP20) family
FY139_10205	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY139_10215	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY139_10220	COG0706	membrane insertase activity
FY139_10225	COG0594	ribonuclease P activity
FY139_10230	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY139_10235	COG0840	transmembrane signaling receptor activity
FY139_10250	COG2226	methyltransferase
FY139_10255	COG3842	ATPase activity
FY139_10260	COG1175	transmembrane transport
FY139_10265	COG0395	ABC-type sugar transport system, permease component
FY139_10280	COG0427	acetyl-CoA hydrolase
FY139_10290	COG3938	Belongs to the proline racemase family
FY139_10295	COG0418	dihydroorotase activity
FY139_10300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY139_10320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY139_10325	COG0166	Belongs to the GPI family
FY139_10330	COG0318	PFAM AMP-dependent synthetase and ligase
FY139_10335	COG3842	ATPase activity
FY139_10340	COG1840	ABC-type Fe3 transport system, periplasmic component
FY139_10345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY139_10350	COG4774	siderophore transport
FY139_10395	COG2326	polyphosphate kinase activity
FY139_10400	COG5002	protein histidine kinase activity
FY139_10405	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY139_10410	COG0573	inorganic phosphate transmembrane transporter activity
FY139_10420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY139_10425	COG0704	Plays a role in the regulation of phosphate uptake
FY139_10430	COG0745	RESPONSE REGULATOR receiver
FY139_10440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY139_10445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY139_10455	COG2967	ApaG domain
FY139_10470	COG0717	Belongs to the dCTP deaminase family
FY139_10480	COG0582	viral genome integration into host DNA
FY139_10505	COG0419	ATPase involved in DNA repair
FY139_10525	COG1396	sequence-specific DNA binding
FY139_10565	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY139_10570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY139_10620	COG0167	dihydroorotate dehydrogenase activity
FY139_10655	COG1959	2 iron, 2 sulfur cluster binding
FY139_10660	COG1201	RNA secondary structure unwinding
FY139_10690	COG1960	acyl-CoA dehydrogenase activity
FY139_10695	COG0183	Belongs to the thiolase family
FY139_10700	COG1024	Enoyl-CoA hydratase
FY139_10700	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY139_10725	COG1320	monovalent cation:proton antiporter activity
FY139_10730	COG2212	antiporter activity
FY139_10735	COG1863	multisubunit Na H antiporter MnhE subunit
FY139_10740	COG0651	ATP synthesis coupled electron transport
FY139_10745	COG1006	Multisubunit Na H antiporter MnhC subunit
FY139_10750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY139_10750	COG2111	Na H antiporter
FY139_10760	COG0840	transmembrane signaling receptor activity
FY139_10770	COG0745	RESPONSE REGULATOR receiver
FY139_10775	COG2198	Histidine kinase
FY139_10775	COG0643	Histidine kinase
FY139_10780	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY139_10785	COG2201	protein-glutamate methylesterase activity
FY139_10790	COG0745	RESPONSE REGULATOR receiver
FY139_10795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY139_10805	COG1766	The M ring may be actively involved in energy transduction
FY139_10810	COG2771	luxR family
FY139_10820	COG2972	Histidine kinase
FY139_10820	COG0840	transmembrane signaling receptor activity
FY139_10825	COG2205	protein histidine kinase activity
FY139_10825	COG2198	Histidine kinase
FY139_10825	COG0784	Response regulator, receiver
FY139_10830	COG1970	mechanosensitive ion channel activity
FY139_10835	COG0436	Aminotransferase
FY139_10850	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY139_10855	COG0424	maF-like protein
FY139_10860	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY139_10870	COG5328	Belongs to the UPF0262 family
FY139_10875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY139_10885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY139_10905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY139_10915	COG1338	Plays a role in the flagellum-specific transport system
FY139_10925	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY139_10935	COG1706	bacterial-type flagellum-dependent cell motility
FY139_10940	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY139_10945	COG4786	Flagellar basal body rod
FY139_10950	COG1677	Flagellar hook-basal body complex protein FliE
FY139_10955	COG1558	bacterial-type flagellum-dependent cell motility
FY139_10960	COG1815	bacterial-type flagellum-dependent cell motility
FY139_10970	COG1157	protein secretion by the type III secretion system
FY139_10975	COG4786	Flagellar basal body rod
FY139_10985	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY139_10990	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY139_10995	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY139_11000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY139_11005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY139_11025	COG1360	Flagellar Motor Protein
FY139_11070	COG5443	negative regulation of bacterial-type flagellum assembly
FY139_11075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY139_11085	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY139_11125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY139_11130	COG1609	Transcriptional regulator
FY139_11135	COG1653	transport
FY139_11140	COG1175	transmembrane transport
FY139_11145	COG0395	ABC-type sugar transport system, permease component
FY139_11150	COG0366	Alpha amylase catalytic
FY139_11155	COG3842	ATPase activity
FY139_11170	COG0129	dihydroxy-acid dehydratase activity
FY139_11175	COG0363	glucosamine-6-phosphate deaminase activity
FY139_11180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY139_11185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_11195	COG2081	HI0933 family
FY139_11215	COG2224	Isocitrate lyase
FY139_11230	COG3842	ATPase activity
FY139_11235	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY139_11240	COG1177	transmembrane transport
FY139_11255	COG2205	protein histidine kinase activity
FY139_11265	COG0248	Ppx GppA phosphatase
FY139_11270	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY139_11275	COG0477	Major facilitator Superfamily
FY139_11305	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY139_11310	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY139_11320	COG0142	geranyltranstransferase activity
FY139_11345	COG0752	glycyl-tRNA synthetase alpha subunit
FY139_11355	COG1704	LemA family
FY139_11360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY139_11370	COG0751	glycine-tRNA ligase activity
FY139_11375	COG1683	Conserved Protein
FY139_11380	COG0840	transmembrane signaling receptor activity
FY139_11390	COG0151	Belongs to the GarS family
FY139_11395	COG2183	response to ionizing radiation
FY139_11400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY139_11425	COG0583	DNA-binding transcription factor activity
FY139_11445	COG0306	phosphate transporter
FY139_11455	COG0561	phosphatase activity
FY139_11460	COG0438	transferase activity, transferring glycosyl groups
FY139_11465	COG2186	Transcriptional regulator
FY139_11475	COG0583	DNA-binding transcription factor activity
FY139_11480	COG0277	FAD linked oxidase domain protein
FY139_11485	COG0277	FAD linked oxidase domain protein
FY139_11490	COG0247	lactate metabolic process
FY139_11500	COG1376	ErfK ybiS ycfS ynhG family protein
FY139_11505	COG2818	Glycosylase
FY139_11515	COG2855	membrane
FY139_11520	COG0583	DNA-binding transcription factor activity
FY139_11550	COG0124	histidyl-tRNA synthetase
FY139_11560	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY139_11565	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY139_11570	COG2259	Doxx family
FY139_11580	COG0459	protein refolding
FY139_11585	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY139_11595	COG0196	riboflavin kinase activity
FY139_11600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY139_11610	COG0590	tRNA wobble adenosine to inosine editing
FY139_11615	COG1187	pseudouridine synthase activity
FY139_11620	COG0742	ribosomal rna small subunit methyltransferase
FY139_11625	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY139_11635	COG0312	modulator of DNA gyrase
FY139_11640	COG0483	inositol monophosphate 1-phosphatase activity
FY139_11650	COG1519	Transferase
FY139_11660	COG1663	tetraacyldisaccharide 4'-kinase activity
FY139_11670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY139_11675	COG0745	RESPONSE REGULATOR receiver
FY139_11680	COG3300	MHYT domain
FY139_11680	COG5001	Diguanylate cyclase
FY139_11685	COG3386	PFAM SMP-30 Gluconolaconase
FY139_11690	COG0800	Aldolase
FY139_11695	COG3734	2-keto-3-deoxy-galactonokinase
FY139_11700	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_11705	COG1414	Transcriptional regulator
FY139_11710	COG2197	response regulator
FY139_11725	COG0598	Magnesium transport protein CorA
FY139_11730	COG3158	transport of potassium into the cell
FY139_11745	COG0356	it plays a direct role in the translocation of protons across the membrane
FY139_11755	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY139_11760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY139_11775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY139_11795	COG0009	L-threonylcarbamoyladenylate synthase
FY139_11805	COG4638	Rieske (2fe-2S)
FY139_11830	COG1960	acyl-CoA dehydrogenase activity
FY139_11845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY139_11850	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY139_11855	COG0840	transmembrane signaling receptor activity
FY139_11865	COG1522	sequence-specific DNA binding
FY139_11890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY139_11895	COG1741	Belongs to the pirin family
FY139_11900	COG1722	exodeoxyribonuclease VII activity
FY139_11905	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY139_11910	COG1268	BioY protein
FY139_11915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY139_11920	COG1122	ATPase activity
FY139_11925	COG3214	Protein conserved in bacteria
FY139_11930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY139_11930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY139_11935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY139_11955	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY139_11970	COG0259	pyridoxamine-phosphate oxidase activity
FY139_12000	COG0312	modulator of DNA gyrase
FY139_12015	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY139_12020	COG0109	protoheme IX farnesyltransferase activity
FY139_12025	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY139_12040	COG3346	SURF1 family
FY139_12045	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY139_12050	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY139_12055	COG0328	RNA-DNA hybrid ribonuclease activity
FY139_12065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY139_12065	COG0678	peroxiredoxin activity
FY139_12075	COG1678	Uncharacterized ACR, COG1678
FY139_12080	COG3237	CsbD-like
FY139_12090	COG5001	Diguanylate cyclase
FY139_12090	COG3300	MHYT domain
FY139_12095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY139_12100	COG0612	Peptidase, M16
FY139_12125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY139_12130	COG1802	Transcriptional regulator
FY139_12145	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY139_12150	COG3609	addiction module antidote protein, CC2985 family
FY139_12155	COG3668	Plasmid stabilization system
FY139_12165	COG1194	a g-specific adenine glycosylase
FY139_12180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY139_12185	COG1196	nuclear chromosome segregation
FY139_12190	COG2514	catechol 2,3-dioxygenase activity
FY139_12195	COG0574	Belongs to the PEP-utilizing enzyme family
FY139_12195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY139_12205	COG1823	symporter activity
FY139_12230	COG0579	oxidoreductase
FY139_12245	COG2895	sulfate adenylyltransferase (ATP) activity
FY139_12250	COG0175	sulfate reduction
FY139_12255	COG0175	sulfate reduction
FY139_12260	COG1959	2 iron, 2 sulfur cluster binding
FY139_12265	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY139_12270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY139_12275	COG4208	sulfate ABC transporter
FY139_12280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY139_12290	COG2200	EAL domain
FY139_12290	COG2203	Gaf domain
FY139_12290	COG2199	diguanylate cyclase activity
FY139_12300	COG1309	transcriptional regulator
FY139_12305	COG1012	belongs to the aldehyde dehydrogenase family
FY139_12310	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY139_12340	COG0625	glutathione transferase activity
FY139_12350	COG0477	Major facilitator Superfamily
FY139_12360	COG3657	addiction module killer protein
FY139_12370	COG1793	dna ligase
FY139_12390	COG1376	ErfK ybiS ycfS ynhG family protein
FY139_12395	COG1376	ErfK ybiS ycfS ynhG family protein
FY139_12400	COG1846	Transcriptional regulator
FY139_12405	COG1764	response to oxidative stress
FY139_12420	COG0488	(ABC) transporter
FY139_12455	COG4221	oxidoreductase activity
FY139_12470	COG0433	COG0433 Predicted ATPase
FY139_12480	COG1733	regulation of RNA biosynthetic process
FY139_12485	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY139_12500	COG0656	L-ascorbic acid biosynthetic process
FY139_12505	COG3781	membrane
FY139_12510	COG2378	regulation of single-species biofilm formation
FY139_12520	COG4106	trans-aconitate 2-methyltransferase activity
FY139_12525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY139_12530	COG0840	transmembrane signaling receptor activity
FY139_12535	COG0583	DNA-binding transcription factor activity
FY139_12550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY139_12570	COG3909	cytochrome
FY139_12575	COG2010	Cytochrome c
FY139_12610	COG0789	Transcriptional regulator
FY139_12635	COG0517	IMP dehydrogenase activity
FY139_12635	COG4175	Glycine betaine
FY139_12640	COG4176	ABC-type proline glycine betaine transport system permease component
FY139_12665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_12675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY139_12675	COG2169	Transcriptional regulator
FY139_12685	COG2514	catechol 2,3-dioxygenase activity
FY139_12700	COG1272	protein, Hemolysin III
FY139_12710	COG1280	lysine exporter protein (LysE YggA)
FY139_12715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY139_12720	COG2111	Na H antiporter
FY139_12720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY139_12725	COG2111	Na H antiporter
FY139_12730	COG1006	Multisubunit Na H antiporter MnhC subunit
FY139_12735	COG0651	ATP synthesis coupled electron transport
FY139_12740	COG1863	multisubunit Na H antiporter MnhE subunit
FY139_12745	COG2212	antiporter activity
FY139_12750	COG1320	monovalent cation:proton antiporter activity
FY139_12755	COG4957	zinc ion binding
FY139_12770	COG2166	iron-sulfur cluster assembly
FY139_12780	COG2205	protein histidine kinase activity
FY139_12825	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY139_12830	COG2983	Belongs to the UPF0260 family
FY139_12845	COG2217	Heavy metal translocating P-type atpase
FY139_12875	COG2814	Major facilitator Superfamily
FY139_12880	COG1621	beta-fructofuranosidase activity
FY139_12885	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY139_12935	COG4695	Portal protein
FY139_13040	COG4235	cytochrome complex assembly
FY139_13045	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY139_13050	COG1138	Cytochrome C-type biogenesis protein
FY139_13055	COG3088	subunit of a heme lyase
FY139_13060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY139_13065	COG0745	RESPONSE REGULATOR receiver
FY139_13070	COG2205	protein histidine kinase activity
FY139_13075	COG3011	Protein conserved in bacteria
FY139_13080	COG3713	MltA-interacting MipA family protein
FY139_13085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY139_13090	COG2202	Pas domain
FY139_13090	COG2205	protein histidine kinase activity
FY139_13100	COG0308	aminopeptidase N
FY139_13105	COG0697	spore germination
FY139_13120	COG0443	Heat shock 70 kDa protein
FY139_13155	COG0604	alcohol dehydrogenase
FY139_13160	COG1733	regulation of RNA biosynthetic process
FY139_13165	COG1968	undecaprenyl-diphosphatase activity
FY139_13170	COG2239	Acts as a magnesium transporter
FY139_13175	COG2814	Major facilitator Superfamily
FY139_13200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY139_13225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY139_13265	COG0741	lytic transglycosylase activity
FY139_13270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_13275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY139_13280	COG0840	transmembrane signaling receptor activity
FY139_13290	COG1758	RNA polymerase activity
FY139_13310	COG0736	holo-[acyl-carrier-protein] synthase activity
FY139_13315	COG0681	Belongs to the peptidase S26 family
FY139_13320	COG0571	ribonuclease III activity
FY139_13325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY139_13335	COG0784	Response regulator, receiver
FY139_13340	COG1381	Involved in DNA repair and RecF pathway recombination
FY139_13350	COG2226	methyltransferase
FY139_13360	COG1418	mRNA catabolic process
FY139_13370	COG0346	lactoylglutathione lyase activity
FY139_13385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_13390	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY139_13395	COG0668	transmembrane transport
FY139_13405	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY139_13435	COG1742	UPF0060 membrane protein
FY139_13450	COG1183	phosphatidylcholine synthase activity
FY139_13455	COG0688	phosphatidylethanolamine metabolic process
FY139_13460	COG5265	(ABC) transporter
FY139_13500	COG2852	Protein conserved in bacteria
FY139_13505	COG0215	cysteine-tRNA ligase activity
FY139_13510	COG4221	oxidoreductase activity
FY139_13515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY139_13520	COG1286	toxin biosynthetic process
FY139_13535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY139_13545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY139_13555	COG0305	Participates in initiation and elongation during chromosome replication
FY139_13575	COG0359	binds to the 23S rRNA
FY139_13585	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY139_13590	COG0360	Binds together with S18 to 16S ribosomal RNA
FY139_13600	COG0667	Aldo Keto reductase
FY139_13605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY139_13615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY139_13620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY139_13630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY139_13635	COG1561	YicC-like family, N-terminal region
FY139_13640	COG0194	GDP metabolic process
FY139_13655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY139_13660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY139_13670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY139_13685	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY139_13705	COG5001	Diguanylate cyclase
FY139_13705	COG3706	GGDEF domain
FY139_13705	COG2203	Gaf domain
FY139_13705	COG4251	negative regulation of phosphorylation
FY139_13710	COG5001	Diguanylate cyclase
FY139_13710	COG3300	MHYT domain
FY139_13715	COG4191	Histidine kinase
FY139_13720	COG4566	intracellular signal transduction
FY139_13730	COG0488	(ABC) transporter
FY139_13735	COG3706	GGDEF domain
FY139_13745	COG0105	UTP biosynthetic process
FY139_13765	COG0314	molybdopterin synthase activity
FY139_13775	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY139_13780	COG0322	excinuclease ABC activity
FY139_13785	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_13810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY139_13815	COG0243	molybdopterin cofactor binding
FY139_13830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY139_13835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY139_13840	COG2226	methyltransferase
FY139_13845	COG0628	permease
FY139_13855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY139_13860	COG0248	Ppx GppA phosphatase
FY139_13885	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY139_13895	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY139_13900	COG0477	Major facilitator Superfamily
FY139_13905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY139_13915	COG0840	transmembrane signaling receptor activity
FY139_13920	COG0659	secondary active sulfate transmembrane transporter activity
FY139_13930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY139_13935	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY139_13945	COG0113	porphobilinogen synthase activity
FY139_13965	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY139_13970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY139_13975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY139_13975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY139_13985	COG1280	lysine exporter protein (LysE YggA)
FY139_13990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY139_13995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY139_14000	COG2814	Major facilitator Superfamily
FY139_14005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY139_14025	COG0416	fatty acid biosynthetic process
FY139_14030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY139_14035	COG0776	regulation of translation
FY139_14070	COG0601	transmembrane transport
FY139_14075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_14080	COG0444	Belongs to the ABC transporter superfamily
FY139_14090	COG0747	negative chemotaxis
FY139_14100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY139_14105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY139_14120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY139_14125	COG0583	DNA-binding transcription factor activity
FY139_14130	COG0737	Belongs to the 5'-nucleotidase family
FY139_14150	COG2897	thiosulfate sulfurtransferase activity
FY139_14165	COG0415	Belongs to the DNA photolyase family
FY139_14175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY139_14205	COG3932	Exopolysaccharide synthesis, ExoD
FY139_14210	COG1238	metal cluster binding
FY139_14285	COG1612	heme a metabolic process
FY139_14295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY139_14300	COG0010	Belongs to the arginase family
FY139_14305	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY139_14310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY139_14320	COG1832	CoA-binding protein
FY139_14350	COG2124	cytochrome p450
FY139_14355	COG2199	diguanylate cyclase activity
FY139_14360	COG0740	serine-type endopeptidase activity
FY139_14365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY139_14370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY139_14380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY139_14405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY139_14410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY139_14415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY139_14425	COG0649	NAD binding
FY139_14435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY139_14440	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY139_14450	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY139_14455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY139_14465	COG0713	ATP synthesis coupled electron transport
FY139_14480	COG1007	ATP synthesis coupled electron transport
FY139_14485	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY139_14485	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY139_14500	COG0442	prolyl-tRNA aminoacylation
FY139_14510	COG1136	(ABC) transporter
FY139_14525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY139_14545	COG0784	Response regulator, receiver
FY139_14555	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY139_14560	COG0477	Major facilitator Superfamily
FY139_14575	COG0557	exoribonuclease II activity
FY139_14580	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY139_14590	COG0758	DNA mediated transformation
FY139_14595	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY139_14605	COG0540	Belongs to the ATCase OTCase family
FY139_14620	COG1960	acyl-CoA dehydrogenase activity
FY139_14625	COG0456	acetyltransferase
FY139_14640	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY139_14645	COG2824	Alkylphosphonate utilization operon protein PhnA
FY139_14650	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY139_14655	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY139_14660	COG0154	amidase activity
FY139_14665	COG0456	acetyltransferase
FY139_14670	COG3811	Belongs to the UPF0386 family
FY139_14685	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY139_14715	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY139_14720	COG0439	Biotin carboxylase
FY139_14725	COG0511	ligase activity, forming carbon-carbon bonds
FY139_14730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY139_14740	COG0436	Aminotransferase
FY139_14760	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_14765	COG1530	ribonuclease E activity
FY139_14775	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY139_14795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY139_14800	COG0384	phenazine biosynthesis protein PhzF
FY139_14820	COG0633	Ferredoxin
FY139_14835	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY139_14840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY139_14850	COG3768	UPF0283 membrane protein
FY139_14855	COG3106	COG3106 Predicted ATPase
FY139_14885	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY139_14920	COG0537	adenosine 5'-monophosphoramidase activity
FY139_14945	COG0052	Belongs to the universal ribosomal protein uS2 family
FY139_14950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY139_14955	COG0528	UMP kinase activity
FY139_14960	COG0233	cytoplasmic translational termination
FY139_14965	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY139_14975	COG0750	zinc metalloprotease
FY139_14980	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY139_14985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY139_14990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY139_14995	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY139_15000	COG3494	Protein of unknown function (DUF1009)
FY139_15005	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY139_15010	COG2186	Transcriptional regulator
FY139_15020	COG0765	amino acid transport
FY139_15025	COG0765	amino acid transport
FY139_15035	COG0372	Belongs to the citrate synthase family
FY139_15050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY139_15075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY139_15080	COG1459	type II secretion system
FY139_15135	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY139_15140	COG0148	phosphopyruvate hydratase activity
FY139_15150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY139_15155	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY139_15155	COG0022	dehydrogenase e1 component
FY139_15160	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY139_15170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY139_15180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY139_15185	COG0697	spore germination
FY139_15200	COG2867	negative regulation of translational initiation
FY139_15205	COG1546	Belongs to the CinA family
FY139_15210	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY139_15210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY139_15220	COG3852	Histidine kinase
FY139_15225	COG2204	response regulator
FY139_15230	COG5000	phosphorelay sensor kinase activity
FY139_15235	COG2204	response regulator
FY139_15240	COG0569	domain protein
FY139_15245	COG1923	regulation of RNA biosynthetic process
FY139_15250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY139_15255	COG3956	TIGRFAM MazG family protein
FY139_15265	COG1648	precorrin-2 dehydrogenase activity
FY139_15265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY139_15305	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY139_15305	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY139_15310	COG0509	glycine decarboxylation via glycine cleavage system
FY139_15315	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY139_15340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY139_15345	COG0564	pseudouridine synthase activity
FY139_15365	COG0251	oxidation-reduction process
FY139_15370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY139_15380	COG1671	Belongs to the UPF0178 family
FY139_15395	COG0450	alkyl hydroperoxide reductase
FY139_15400	COG0625	glutathione transferase activity
FY139_15410	COG2801	Transposase and inactivated derivatives
FY139_15415	COG0431	NADPH-dependent FMN reductase
FY139_15425	COG0798	PFAM Bile acid sodium symporter
FY139_15430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY139_15445	COG0321	lipoyl(octanoyl) transferase activity
FY139_15445	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY139_15450	COG0084	hydrolase, TatD family'
FY139_15455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY139_15465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY139_15515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY139_15520	COG2095	MarC family integral membrane protein
FY139_15525	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY139_15525	COG0517	IMP dehydrogenase activity
FY139_15525	COG0617	tRNA 3'-terminal CCA addition
FY139_15535	COG0629	single-stranded DNA binding
FY139_15540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY139_15550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY139_15570	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY139_15575	COG1121	(ABC) transporter
FY139_15595	COG0667	Aldo Keto reductase
FY139_15605	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY139_15690	COG2239	Acts as a magnesium transporter
FY139_15695	COG0243	molybdopterin cofactor binding
FY139_15705	COG0242	peptide deformylase activity
FY139_15715	COG2202	Pas domain
FY139_15715	COG2205	protein histidine kinase activity
FY139_15725	COG0321	lipoyl(octanoyl) transferase activity
FY139_15730	COG1064	alcohol dehydrogenase
FY139_15760	COG1862	Preprotein translocase
FY139_15780	COG2124	cytochrome p450
FY139_15795	COG0596	Alpha beta hydrolase
FY139_15805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY139_15810	COG0626	cystathionine gamma-synthase activity
FY139_15815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_15820	COG4597	amino acid ABC transporter
FY139_15825	COG0765	amino acid transport
FY139_15830	COG1126	abc transporter atp-binding protein
FY139_15845	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY139_15860	COG0436	Aminotransferase
FY139_15890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY139_15900	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY139_15905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY139_15910	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY139_15925	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY139_15930	COG1489	DNA binding
FY139_15935	COG0024	Methionine aminopeptidase
FY139_15940	COG2003	Belongs to the UPF0758 family
FY139_15955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY139_15980	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY139_15985	COG0546	phosphoglycolate phosphatase activity
FY139_15995	COG0114	fumarate hydratase activity
FY139_16005	COG0504	CTP synthase activity
FY139_16015	COG0149	triose-phosphate isomerase activity
FY139_16025	COG0187	DNA topoisomerase II activity
FY139_16035	COG0740	serine-type endopeptidase activity
FY139_16045	COG0640	Transcriptional regulator
FY139_16050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY139_16055	COG0745	RESPONSE REGULATOR receiver
FY139_16070	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY139_16070	COG3264	Mechanosensitive ion channel
FY139_16135	COG1127	ABC transporter
FY139_16140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY139_16145	COG4948	Mandelate Racemase Muconate Lactonizing
FY139_16155	COG0280	phosphate acetyltransferase
FY139_16155	COG0281	malic enzyme
FY139_16165	COG0778	Nitroreductase
FY139_16170	COG0823	Involved in the tonB-independent uptake of proteins
FY139_16185	COG1368	sulfuric ester hydrolase activity
FY139_16210	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY139_16230	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY139_16250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY139_16265	COG0318	PFAM AMP-dependent synthetase and ligase
FY139_16275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY139_16275	COG0512	Glutamine amidotransferase of anthranilate synthase
FY139_16280	COG0343	queuine tRNA-ribosyltransferase activity
FY139_16285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY139_16300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY139_16315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY139_16320	COG0134	indole-3-glycerol-phosphate synthase activity
FY139_16325	COG0315	cyclic pyranopterin monophosphate synthase activity
FY139_16330	COG0303	'Molybdopterin
FY139_16335	COG3706	GGDEF domain
FY139_16345	COG0475	glutathione-regulated potassium exporter activity
FY139_16345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY139_16355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY139_16365	COG2814	Major facilitator Superfamily
FY139_16370	COG0746	molybdenum cofactor guanylyltransferase activity
FY139_16375	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY139_16380	COG0739	heme binding
FY139_16385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY139_16390	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY139_16395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY139_16400	COG0805	protein transport
FY139_16405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY139_16410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY139_16415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY139_16420	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY139_16425	COG1472	Belongs to the glycosyl hydrolase 3 family
FY139_16435	COG0018	arginyl-trna synthetase
FY139_16440	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY139_16465	COG0525	valine-tRNA ligase activity
FY139_16475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY139_16615	COG1525	nuclease
FY139_16690	COG3567	Phage-associated protein, HI1409 family
FY139_16705	COG5410	chromosome segregation
FY139_16740	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY139_16920	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY139_16925	COG1546	Belongs to the CinA family
FY139_16925	COG1058	Belongs to the CinA family
FY139_16930	COG0589	response to stress
FY139_16935	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY139_16945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY139_16955	COG0640	Transcriptional regulator
FY139_16960	COG1914	H( )-stimulated, divalent metal cation uptake system
FY139_16970	COG1132	(ABC) transporter
FY139_16975	COG0628	permease
FY139_17010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY139_17020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY139_17030	COG0302	gtp cyclohydrolase
FY139_17035	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY139_17040	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY139_17050	COG0517	IMP dehydrogenase activity
FY139_17050	COG0516	GMP reductase activity
FY139_17085	COG1760	l-serine dehydratase
FY139_17125	COG0583	DNA-binding transcription factor activity
FY139_17140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY139_17140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY139_17150	COG0347	Belongs to the P(II) protein family
FY139_17155	COG0174	glutamine synthetase
FY139_17185	COG0697	spore germination
FY139_17195	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY139_17205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY139_17235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY139_17245	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY139_17250	COG2186	Transcriptional regulator
FY139_17260	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY139_17265	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY139_17270	COG3845	ABC transporter
FY139_17275	COG1183	phosphatidylcholine synthase activity
FY139_17280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY139_17285	COG0679	Auxin Efflux Carrier
FY139_17290	COG0785	Cytochrome C biogenesis protein
FY139_17310	COG1278	Cold shock
FY139_17360	COG0577	efflux transmembrane transporter activity
FY139_17360	COG1136	(ABC) transporter
FY139_17365	COG1136	(ABC) transporter
FY139_17365	COG0577	efflux transmembrane transporter activity
FY139_17390	COG2151	metal-sulfur cluster biosynthetic enzyme
FY139_17395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY139_17400	COG0719	Fe-S assembly protein
FY139_17405	COG0396	ATPase activity
FY139_17410	COG0719	Fe-S assembly protein
FY139_17415	COG1104	cysteine desulfurase activity
FY139_17420	COG2945	thiolester hydrolase activity
FY139_17425	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY139_17430	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY139_17440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY139_17445	COG2833	Protein of unknown function (DUF455)
FY139_17450	COG0739	heme binding
FY139_17455	COG0513	Belongs to the DEAD box helicase family
FY139_17480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY139_17490	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY139_17495	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY139_17500	COG0047	phosphoribosylformylglycinamidine synthase activity
FY139_17515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY139_17520	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY139_17540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY139_17545	COG2814	Major facilitator Superfamily
FY139_17550	COG0483	inositol monophosphate 1-phosphatase activity
FY139_17555	COG0483	inositol monophosphate 1-phosphatase activity
FY139_17560	COG0037	tRNA processing
FY139_17565	COG2066	Belongs to the glutaminase family
FY139_17570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY139_17575	COG0861	Integral membrane protein TerC family
FY139_17590	COG1280	lysine exporter protein (LysE YggA)
FY139_17600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY139_17605	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY139_17615	COG0538	isocitrate dehydrogenase activity
FY139_17625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY139_17630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY139_17635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_17640	COG2313	pseudouridylate synthase activity
FY139_17650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_17655	COG4215	(ABC) transporter
FY139_17665	COG5425	PFAM Usg family protein
FY139_17675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY139_17680	COG1522	sequence-specific DNA binding
FY139_17685	COG1573	uracil-dna glycosylase
FY139_17695	COG2205	protein histidine kinase activity
FY139_17695	COG2202	Pas domain
FY139_17700	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY139_17705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY139_17710	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY139_17725	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY139_17730	COG0842	Transport permease protein
FY139_17735	COG1131	(ABC) transporter
FY139_17740	COG0730	response to heat
FY139_17740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY139_17760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY139_17765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY139_17785	COG0129	dihydroxy-acid dehydratase activity
FY139_17790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY139_17795	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY139_17805	COG3739	integral membrane protein
FY139_17810	COG0203	ribosomal protein L17
FY139_17815	COG0202	RNA polymerase activity
FY139_17820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY139_17825	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY139_17830	COG0563	adenylate kinase activity
FY139_17835	COG0201	protein transport
FY139_17840	COG0200	Binds to the 23S rRNA
FY139_17845	COG1841	ribosomal large subunit assembly
FY139_17850	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY139_17855	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY139_17860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY139_17865	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY139_17870	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY139_17875	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY139_17880	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY139_17885	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY139_17890	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY139_17895	COG0255	Belongs to the universal ribosomal protein uL29 family
FY139_17900	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY139_17905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY139_17910	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY139_17915	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY139_17920	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY139_17925	COG0089	rRNA binding
FY139_17930	COG0088	Forms part of the polypeptide exit tunnel
FY139_17935	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY139_17940	COG0051	transcription antitermination factor activity, RNA binding
FY139_17945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY139_17950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY139_17955	COG0049	tRNA binding
FY139_17960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY139_17980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY139_17985	COG0085	RNA polymerase activity
FY139_17990	COG0222	ribosome binding
FY139_17995	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY139_18000	COG0081	regulation of translation
FY139_18005	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY139_18015	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY139_18025	COG1086	Polysaccharide biosynthesis protein
FY139_18030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY139_18035	COG0861	Integral membrane protein TerC family
FY139_18040	COG3895	Periplasmic Protein
FY139_18060	COG1132	(ABC) transporter
FY139_18065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY139_18085	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY139_18120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_18120	COG2198	Histidine kinase
FY139_18120	COG2205	protein histidine kinase activity
FY139_18120	COG0784	Response regulator, receiver
FY139_18125	COG0784	Response regulator, receiver
FY139_18130	COG2202	Pas domain
FY139_18130	COG3920	Histidine kinase
FY139_18135	COG0784	Response regulator, receiver
FY139_18140	COG4251	negative regulation of phosphorylation
FY139_18155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY139_18160	COG1607	acyl-coa hydrolase
FY139_18180	COG2910	NAD(P)H-binding
FY139_18185	COG1733	regulation of RNA biosynthetic process
FY139_18200	COG0556	nucleotide-excision repair
FY139_18210	COG2382	esterase
FY139_18230	COG0484	heat shock protein binding
FY139_18250	COG3706	GGDEF domain
FY139_18270	COG1840	ABC-type Fe3 transport system, periplasmic component
FY139_18275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY139_18290	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY139_18300	COG2207	Transcriptional regulator
FY139_18305	COG1064	alcohol dehydrogenase
FY139_18310	COG1252	NADH dehydrogenase
FY139_18315	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY139_18320	COG2197	response regulator
FY139_18325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY139_18360	COG0656	L-ascorbic acid biosynthetic process
FY139_18375	COG0440	acetolactate synthase activity
FY139_18380	COG0028	Belongs to the TPP enzyme family
FY139_18390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY139_18395	COG0560	Phosphoserine phosphatase
FY139_18395	COG3830	Belongs to the UPF0237 family
FY139_18415	COG0330	HflC and HflK could
FY139_18420	COG0330	HflC and HflK could
FY139_18430	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY139_18465	COG0277	FAD linked oxidase domain protein
FY139_18470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY139_18510	COG1335	isochorismatase
FY139_18535	COG2264	protein methyltransferase activity
FY139_18540	COG1999	signal sequence binding
FY139_18550	COG0835	chemotaxis
FY139_18560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY139_18565	COG0583	DNA-binding transcription factor activity
FY139_18575	COG1247	-acetyltransferase
FY139_18585	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY139_18590	COG0497	DNA recombination
FY139_18595	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY139_18605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY139_18610	COG0849	cell division
FY139_18615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY139_18620	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY139_18625	COG0477	Major facilitator Superfamily
FY139_18630	COG5001	Diguanylate cyclase
FY139_18635	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY139_18640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY139_18645	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY139_18655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY139_18660	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY139_18670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY139_18685	COG0275	rRNA processing
FY139_18690	COG2001	Belongs to the MraZ family
FY139_18715	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY139_18745	COG4106	trans-aconitate 2-methyltransferase activity
FY139_18765	COG2226	methyltransferase
FY139_18775	COG2267	carboxylic ester hydrolase activity
FY139_18780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY139_18795	COG0251	oxidation-reduction process
FY139_18810	COG1376	ErfK ybiS ycfS ynhG family protein
FY139_18815	COG2814	Major facilitator Superfamily
FY139_18845	COG1012	belongs to the aldehyde dehydrogenase family
FY139_18850	COG0174	glutamine synthetase
FY139_18855	COG0531	amino acid
FY139_18865	COG1737	Transcriptional regulator
FY139_18870	COG2182	Extracellular solute-binding protein
FY139_18885	COG3842	ATPase activity
FY139_18945	COG2968	Membrane
FY139_18955	COG0432	Pfam Uncharacterised protein family UPF0047
FY139_18970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY139_18975	COG0358	DNA primase activity
FY139_18995	COG0505	Belongs to the CarA family
FY139_19000	COG0534	Mate efflux family protein
FY139_19015	COG2321	neutral zinc metallopeptidase
FY139_19030	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY139_19040	COG3706	GGDEF domain
FY139_19055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY139_19065	COG1522	sequence-specific DNA binding
FY139_19070	COG0492	ferredoxin-NADP+ reductase activity
FY139_19075	COG0583	DNA-binding transcription factor activity
FY139_19085	COG1902	pentaerythritol trinitrate reductase activity
FY139_19110	COG0387	Pfam Sodium calcium exchanger
FY139_19115	COG0436	Aminotransferase
FY139_19120	COG2199	diguanylate cyclase activity
FY139_19120	COG2200	EAL domain
FY139_19135	COG1278	Cold shock
FY139_19140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY139_19150	COG1846	Transcriptional regulator
FY139_19155	COG0745	RESPONSE REGULATOR receiver
FY139_19165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY139_19185	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY139_19195	COG1496	oxidoreductase activity
FY139_19210	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY139_19220	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY139_19235	COG0840	transmembrane signaling receptor activity
FY139_19240	COG1012	belongs to the aldehyde dehydrogenase family
FY139_19245	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY139_19250	COG5001	Diguanylate cyclase
FY139_19250	COG3300	MHYT domain
FY139_19255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY139_19260	COG5001	Diguanylate cyclase
FY139_19270	COG0193	aminoacyl-tRNA hydrolase activity
FY139_19280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY139_19305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY139_19315	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY139_19315	COG2857	Cytochrome c1
FY139_19335	COG1132	(ABC) transporter
FY139_19345	COG1132	(ABC) transporter
FY139_19355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY139_19370	COG0408	coproporphyrinogen oxidase activity
FY139_19385	COG0617	tRNA 3'-terminal CCA addition
FY139_19400	COG0714	Associated with various cellular activities
FY139_19420	COG0454	-acetyltransferase
FY139_19435	COG0477	Major facilitator Superfamily
FY139_19445	COG0435	Glutathione S-transferase
FY139_19450	COG0494	nUDIX hydrolase
FY139_19460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY139_19465	COG3135	benzoate transporter
FY139_19490	COG0740	serine-type endopeptidase activity
FY139_19505	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY139_19510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY139_19535	COG4175	Glycine betaine
FY139_19555	COG1435	thymidine kinase activity
FY139_19580	COG1629	transport
FY139_19580	COG4771	TonB-dependent receptor
FY139_19590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY139_19590	COG0512	Glutamine amidotransferase of anthranilate synthase
FY139_19605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY139_19615	COG0366	Alpha amylase catalytic
FY139_19620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_19640	COG1160	GTP binding
FY139_19660	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY139_19670	COG0024	Methionine aminopeptidase
FY139_19680	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_19700	COG0583	DNA-binding transcription factor activity
FY139_19715	COG0402	S-adenosylhomocysteine deaminase activity
FY139_19725	COG1304	FMN binding
FY139_19735	COG1309	transcriptional regulator
FY139_19740	COG1686	Belongs to the peptidase S11 family
FY139_19750	COG2351	hydroxyisourate hydrolase activity
FY139_19755	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY139_19780	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY139_19790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_19790	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY139_19800	COG0513	Belongs to the DEAD box helicase family
FY139_19810	COG2259	Doxx family
FY139_19815	COG1376	ErfK ybiS ycfS ynhG family protein
FY139_19825	COG2308	Evidence 4 Homologs of previously reported genes of
FY139_19835	COG1305	Transglutaminase-like
FY139_19860	COG4214	carbohydrate transport
FY139_19870	COG4213	ABC transporter substrate-binding protein
FY139_19925	COG2948	multi-organism process
FY139_19935	COG3701	Conjugal transfer protein
FY139_19940	COG3846	protein secretion by the type IV secretion system
FY139_19955	COG3451	type IV secretory pathway VirB4
FY139_19970	COG4962	Type ii secretion system protein e
FY139_19995	COG0583	DNA-binding transcription factor activity
FY139_20005	COG1566	PFAM secretion protein HlyD family protein
FY139_20020	COG2207	Transcriptional regulator
FY139_20025	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_20035	COG0583	DNA-binding transcription factor activity
FY139_20045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY139_20060	COG0583	DNA-binding transcription factor activity
FY139_20070	COG0741	lytic transglycosylase activity
FY139_20095	COG1192	Involved in chromosome partitioning
FY139_20130	COG2814	Major facilitator Superfamily
FY139_20140	COG5489	Protein of unknown function (DUF736)
FY139_20155	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY139_20185	COG1204	response to ionizing radiation
FY139_20200	COG0514	ATP-dependent DNA helicase (RecQ)
FY139_20250	COG0583	DNA-binding transcription factor activity
FY139_20255	COG1902	pentaerythritol trinitrate reductase activity
FY139_20260	COG0583	DNA-binding transcription factor activity
FY139_20275	COG1335	isochorismatase
FY139_20280	COG0583	DNA-binding transcription factor activity
FY139_20285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY139_20295	COG4584	PFAM Integrase catalytic
FY139_20310	COG0840	transmembrane signaling receptor activity
FY139_20325	COG0646	methionine synthase
FY139_20325	COG1410	methionine synthase
FY139_20340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_20370	COG1215	transferase activity, transferring glycosyl groups
FY139_20400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY139_20415	COG2346	COG2346, Truncated hemoglobins
FY139_20435	COG1309	transcriptional regulator
FY139_20450	COG0494	nUDIX hydrolase
FY139_20460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_20465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_20495	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY139_20500	COG0830	nickel cation binding
FY139_20505	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY139_20520	COG0804	urea catabolic process
FY139_20525	COG1442	glycosyl transferase family 8
FY139_20530	COG3755	Protein conserved in bacteria
FY139_20540	COG0832	Belongs to the urease beta subunit family
FY139_20545	COG3813	Protein conserved in bacteria
FY139_20550	COG0831	urea catabolic process
FY139_20555	COG0829	nickel cation binding
FY139_20575	COG0411	ABC transporter
FY139_20585	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY139_20600	COG0174	glutamine synthetase
FY139_20605	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_20610	COG2198	Histidine kinase
FY139_20610	COG5002	protein histidine kinase activity
FY139_20610	COG0784	Response regulator, receiver
FY139_20625	COG0726	polysaccharide deacetylase
FY139_20660	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY139_20735	COG0564	pseudouridine synthase activity
FY139_20745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY139_20755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY139_20780	COG0346	lactoylglutathione lyase activity
FY139_20790	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY139_20800	COG2832	Protein of unknown function (DUF454)
FY139_20805	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY139_20810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_20815	COG4558	Periplasmic binding protein
FY139_20825	COG3721	Heme iron utilization protein
FY139_20840	COG3655	Transcriptional regulator
FY139_20865	COG2205	protein histidine kinase activity
FY139_20905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_20910	COG4605	iron ion homeostasis
FY139_20915	COG4604	ABC transporter, ATP-binding protein
FY139_20920	COG0783	Belongs to the Dps family
FY139_20935	COG0840	transmembrane signaling receptor activity
FY139_20935	COG2972	Histidine kinase
FY139_20940	COG0656	L-ascorbic acid biosynthetic process
FY139_20945	COG2814	Major facilitator Superfamily
FY139_20955	COG0583	DNA-binding transcription factor activity
FY139_20960	COG0657	acetylesterase activity
FY139_20965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_20985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY139_20990	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY139_20995	COG0288	reversible hydration of carbon dioxide
FY139_21005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY139_21025	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY139_21030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY139_21035	COG0778	Nitroreductase
FY139_21040	COG2267	carboxylic ester hydrolase activity
FY139_21045	COG0251	oxidation-reduction process
FY139_21050	COG1335	isochorismatase
FY139_21055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_21065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY139_21080	COG1175	transmembrane transport
FY139_21085	COG0395	ABC-type sugar transport system, permease component
FY139_21090	COG3842	ATPase activity
FY139_21095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_21105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY139_21120	COG4608	Belongs to the ABC transporter superfamily
FY139_21125	COG0444	Belongs to the ABC transporter superfamily
FY139_21130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_21135	COG0601	transmembrane transport
FY139_21190	COG2159	amidohydrolase
FY139_21195	COG1960	acyl-CoA dehydrogenase activity
FY139_21225	COG0745	RESPONSE REGULATOR receiver
FY139_21235	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY139_21235	COG1902	pentaerythritol trinitrate reductase activity
FY139_21240	COG3842	ATPase activity
FY139_21250	COG1840	ABC-type Fe3 transport system, periplasmic component
FY139_21255	COG1840	ABC-type Fe3 transport system, periplasmic component
FY139_21260	COG0745	RESPONSE REGULATOR receiver
FY139_21270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY139_21275	COG0583	DNA-binding transcription factor activity
FY139_21280	COG1278	Cold shock
FY139_21320	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY139_21325	COG1309	transcriptional regulator
FY139_21330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_21335	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY139_21345	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY139_21350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY139_21370	COG0583	DNA-binding transcription factor activity
FY139_21375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_21380	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY139_21385	COG4149	molybdate abc transporter
FY139_21390	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY139_21405	COG2022	thiamine diphosphate biosynthetic process
FY139_21420	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY139_21430	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY139_21440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY139_21460	COG1132	(ABC) transporter
FY139_21465	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY139_21510	COG4166	transmembrane transport
FY139_21515	COG0601	transmembrane transport
FY139_21520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_21535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY139_21540	COG3142	Participates in the control of copper homeostasis
FY139_21545	COG2814	Major facilitator Superfamily
FY139_21560	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_21565	COG1737	Transcriptional regulator
FY139_21575	COG3842	ATPase activity
FY139_21585	COG0395	ABC-type sugar transport system, permease component
FY139_21605	COG2188	Transcriptional regulator
FY139_21610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY139_21615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY139_21620	COG1940	carbohydrate kinase activity
FY139_21630	COG0671	phosphoesterase, PA-phosphatase related
FY139_21635	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY139_21640	COG0156	8-amino-7-oxononanoate synthase activity
FY139_21650	COG0729	surface antigen
FY139_21660	COG0835	chemotaxis
FY139_21670	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY139_21675	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY139_21680	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY139_21685	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY139_21690	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY139_21695	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY139_21710	COG4974	Belongs to the 'phage' integrase family
FY139_21735	COG1280	lysine exporter protein (LysE YggA)
FY139_21745	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY139_21750	COG0567	Dehydrogenase, E1 component
FY139_21755	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY139_21760	COG0045	succinate-CoA ligase (ADP-forming) activity
FY139_21765	COG0039	L-malate dehydrogenase activity
FY139_21770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY139_21820	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY139_21825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY139_21830	COG0181	hydroxymethylbilane synthase activity
FY139_21870	COG1872	DUF167
FY139_21875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY139_21885	COG1217	gtp-binding protein TYPA
FY139_21890	COG0339	signal peptide processing
FY139_21895	COG1846	Transcriptional regulator
FY139_21905	COG0137	argininosuccinate synthase activity
FY139_21915	COG1280	lysine exporter protein (LysE YggA)
FY139_21920	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY139_21925	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY139_21935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY139_21950	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY139_21955	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY139_21960	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY139_21970	COG4181	ATPase activity
FY139_21980	COG0670	Belongs to the BI1 family
FY139_21995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY139_22000	COG4133	protoheme IX ABC transporter activity
FY139_22005	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY139_22010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY139_22035	COG2917	probably involved in intracellular septation
FY139_22040	COG0552	protein localization to endoplasmic reticulum
FY139_22045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY139_22050	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY139_22065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY139_22070	COG0287	Prephenate dehydrogenase
FY139_22070	COG1605	Chorismate mutase
FY139_22075	COG0228	four-way junction DNA binding
FY139_22080	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY139_22085	COG0336	Belongs to the RNA methyltransferase TrmD family
FY139_22095	COG0335	large ribosomal subunit rRNA binding
FY139_22100	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY139_22105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY139_22120	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY139_22140	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY139_22160	COG0488	(ABC) transporter
FY139_22170	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY139_22180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY139_22185	COG0142	geranyltranstransferase activity
FY139_22190	COG2885	chlorophyll binding
FY139_22195	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY139_22200	COG2223	nitrite transmembrane transporter activity
FY139_22205	COG1349	DNA-binding transcription factor activity
FY139_22210	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY139_22215	COG2197	response regulator
FY139_22220	COG1132	(ABC) transporter
FY139_22230	COG3459	Glycosyltransferase 36 associated
FY139_22235	COG1473	amidohydrolase
FY139_22240	COG0579	oxidoreductase
FY139_22250	COG0129	dihydroxy-acid dehydratase activity
FY139_22255	COG2084	Dehydrogenase
FY139_22260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY139_22265	COG0277	FAD linked oxidase domain protein
FY139_22270	COG2186	Transcriptional regulator
FY139_22280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY139_22285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY139_22290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY139_22295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY139_22305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY139_22310	COG0495	leucyl-tRNA aminoacylation
FY139_22325	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY139_22330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY139_22345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY139_22350	COG1946	Acyl-CoA thioesterase
FY139_22355	COG0347	Belongs to the P(II) protein family
FY139_22360	COG0004	ammonium transporteR
FY139_22365	COG1674	ftsk spoiiie
FY139_22370	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY139_22385	COG0745	RESPONSE REGULATOR receiver
FY139_22395	COG1329	Transcriptional regulator
FY139_22405	COG2270	Major facilitator Superfamily
FY139_22420	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_22435	COG0494	nUDIX hydrolase
FY139_22440	COG2861	carbohydrate metabolic process
FY139_22445	COG0793	Belongs to the peptidase S41A family
FY139_22455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY139_22460	COG0799	negative regulation of ribosome biogenesis
FY139_22465	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY139_22470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY139_22475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY139_22480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY139_22495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY139_22500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY139_22525	COG0066	3-isopropylmalate dehydratase activity
FY139_22530	COG0473	3-isopropylmalate dehydrogenase activity
FY139_22535	COG1858	cytochrome C peroxidase
FY139_22540	COG1797	cobyrinic acid a,c-diamide synthase activity
FY139_22550	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY139_22615	COG1492	cobalamin metabolic process
FY139_22630	COG4948	Mandelate Racemase Muconate Lactonizing
FY139_22635	COG3254	rhamnose metabolic process
FY139_22640	COG0246	Mannitol dehydrogenase
FY139_22645	COG1063	alcohol dehydrogenase
FY139_22670	COG1129	ABC transporter
FY139_22675	COG2186	Transcriptional regulator
FY139_22680	COG2721	sulfolactate sulfo-lyase activity
FY139_22685	COG0138	bifunctional purine biosynthesis protein purh
FY139_22695	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY139_22695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY139_22700	COG0501	Belongs to the peptidase M48B family
FY139_22720	COG0357	Ribosomal RNA small subunit methyltransferase G
FY139_22725	COG0445	tRNA wobble uridine modification
FY139_22730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY139_22735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY139_22740	COG1981	membrane
FY139_22745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY139_22750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY139_22755	COG0424	maF-like protein
FY139_22760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY139_22765	COG0237	dephospho-CoA kinase activity
FY139_22775	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY139_22780	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY139_22790	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY139_22815	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY139_22830	COG0135	phosphoribosylanthranilate isomerase activity
FY139_22835	COG0133	tryptophan synthase activity
FY139_22840	COG0159	tryptophan synthase activity
FY139_22845	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY139_22860	COG1074	ATP-dependent DNA helicase activity
FY139_22870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY139_22875	COG0802	atpase or kinase
FY139_22880	COG2205	protein histidine kinase activity
FY139_22885	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY139_22890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY139_22895	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY139_22895	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY139_22900	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY139_22905	COG0642	Histidine kinase
FY139_22910	COG0745	RESPONSE REGULATOR receiver
FY139_22915	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY139_22925	COG1652	LysM domain
FY139_22930	COG1072	(Pantothenic acid kinase))
FY139_22935	COG0140	phosphoribosyl-ATP diphosphatase activity
FY139_22940	COG0107	imidazoleglycerol-phosphate synthase activity
FY139_22945	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY139_22950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY139_22960	COG0131	Imidazoleglycerol-phosphate dehydratase
FY139_22965	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY139_22970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY139_22980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY139_22995	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY139_23005	COG1643	Atp-dependent helicase
FY139_23050	COG1940	carbohydrate kinase activity
FY139_23070	COG1072	(Pantothenic acid kinase))
FY139_23080	COG1780	Probably involved in ribonucleotide reductase function
FY139_23100	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY139_23130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY139_23140	COG2813	Specifically methylates the guanine in position
FY139_23145	COG1185	polyribonucleotide nucleotidyltransferase activity
FY139_23150	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY139_23155	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY139_23160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY139_23165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY139_23165	COG3064	Membrane
FY139_23180	COG0779	Required for maturation of 30S ribosomal subunits
FY139_23185	COG2814	Major facilitator Superfamily
FY139_23195	COG2951	lytic endotransglycosylase activity
FY139_23200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY139_23210	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY139_23215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY139_23230	COG2816	NAD+ diphosphatase activity
FY139_23235	COG0077	Prephenate dehydratase
FY139_23235	COG1605	Chorismate mutase
FY139_23240	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY139_23245	COG3474	cytochrome
FY139_23255	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY139_23260	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY139_23265	COG1278	Cold shock
FY139_23270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY139_23280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY139_23280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY139_23285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY139_23315	COG2900	Belongs to the SlyX family
FY139_23325	COG0484	heat shock protein binding
FY139_23330	COG0443	Heat shock 70 kDa protein
FY139_23345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY139_23350	COG1744	ABC transporter substrate-binding protein PnrA-like
FY139_23355	COG3845	ABC transporter
FY139_23360	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY139_23365	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY139_23370	COG0295	cytidine deaminase activity
FY139_23375	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY139_23380	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY139_23385	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY139_23395	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY139_23400	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY139_23405	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY139_23415	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY139_23420	COG1845	cytochrome c oxidase, subunit III
FY139_23425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY139_23430	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY139_23435	COG0477	Major facilitator Superfamily
FY139_23440	COG0067	glutamate synthase
FY139_23440	COG0070	glutamate synthase
FY139_23440	COG0069	glutamate synthase activity
FY139_23445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY139_23460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY139_23470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY139_23500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY139_23520	COG0848	biopolymer transport protein
FY139_23530	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY139_23545	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY139_23550	COG3454	Phosphonate metabolism
FY139_23555	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY139_23560	COG3639	organic phosphonate transmembrane transporter activity
FY139_23565	COG3639	organic phosphonate transmembrane transporter activity
FY139_23575	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY139_23585	COG4778	phosphonate C-P lyase system protein PhnL
FY139_23590	COG4107	phosphonate C-P lyase system protein PhnK
FY139_23595	COG3627	carbon phosphorus lyase activity
FY139_23600	COG3626	phosphonate metabolism
FY139_23605	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY139_23610	COG3624	Phosphonate C-P lyase system protein PhnG
FY139_23615	COG2188	Transcriptional regulator
FY139_23620	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY139_23625	COG0837	glucose binding
FY139_23630	COG1803	Methylglyoxal synthase
FY139_23635	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY139_23640	COG4166	transmembrane transport
FY139_23645	COG4174	ABC transporter (Permease)
FY139_23650	COG4239	(ABC) transporter, permease
FY139_23655	COG4172	Belongs to the ABC transporter superfamily
FY139_23660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_23665	COG0174	glutamine synthetase
FY139_23670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY139_23675	COG3265	gluconokinase activity
FY139_23680	COG1174	glycine betaine transport
FY139_23685	COG1125	glycine betaine transport
FY139_23690	COG1174	glycine betaine transport
FY139_23695	COG1732	Glycine betaine
FY139_23705	COG1959	2 iron, 2 sulfur cluster binding
FY139_23710	COG1840	ABC-type Fe3 transport system, periplasmic component
FY139_23720	COG4269	membrane
FY139_23735	COG0697	spore germination
FY139_23750	COG0791	NLP P60 protein
FY139_23760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY139_23765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY139_23800	COG4964	Belongs to the GSP D family
FY139_23845	COG3422	double-strand break repair
FY139_23850	COG3757	hydrolase, family 25
FY139_23855	COG0697	spore germination
FY139_23860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY139_23875	COG0492	ferredoxin-NADP+ reductase activity
FY139_23890	COG0481	GTPase activity
FY139_23895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY139_23910	COG1396	sequence-specific DNA binding
FY139_23925	COG1917	Cupin 2, conserved barrel domain protein
FY139_23925	COG2169	Transcriptional regulator
FY139_23930	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY139_23955	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY139_23960	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY139_23965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY139_23975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY139_23980	COG0072	phenylalanine-tRNA ligase activity
FY139_23980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY139_23985	COG0667	Aldo Keto reductase
FY139_24005	COG4977	sequence-specific DNA binding
FY139_24030	COG1570	exodeoxyribonuclease VII activity
FY139_24035	COG4948	Mandelate Racemase Muconate Lactonizing
FY139_24045	COG1846	Transcriptional regulator
FY139_24055	COG2309	aminopeptidase activity
FY139_24065	COG1393	Belongs to the ArsC family
FY139_24080	COG1309	transcriptional regulator
FY139_24090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY139_24090	COG0519	Catalyzes the synthesis of GMP from XMP
FY139_24105	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY139_24135	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY139_24145	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY139_24155	COG1968	undecaprenyl-diphosphatase activity
FY139_24170	COG0284	orotidine-5'-phosphate decarboxylase activity
FY139_24180	COG3963	phosphatidate phosphatase activity
FY139_24190	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY139_24195	COG0792	nuclease activity
FY139_24210	COG1175	transmembrane transport
FY139_24215	COG0395	ABC-type sugar transport system, permease component
FY139_24220	COG3842	ATPase activity
FY139_24230	COG0189	ligase activity
FY139_24240	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY139_24245	COG1280	lysine exporter protein (LysE YggA)
FY139_24250	COG0756	dUTP diphosphatase activity
FY139_24255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY139_24260	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY139_24275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY139_24280	COG2226	methyltransferase
FY139_24285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY139_24290	COG1024	Enoyl-CoA hydratase
FY139_24295	COG0268	Binds directly to 16S ribosomal RNA
FY139_24300	COG1192	Involved in chromosome partitioning
FY139_24305	COG1475	DNA binding
FY139_24310	COG0640	Transcriptional regulator
FY139_24325	COG1126	abc transporter atp-binding protein
FY139_24330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY139_24335	COG1609	Transcriptional regulator
FY139_24370	COG3239	Fatty acid desaturase
FY139_24380	COG1278	Cold shock
FY139_24460	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY139_24460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY139_24495	COG4191	Histidine kinase
FY139_24500	COG1132	(ABC) transporter
FY139_24510	COG0640	Transcriptional regulator
FY139_24540	COG4977	sequence-specific DNA binding
FY139_24545	COG2211	Major facilitator Superfamily
FY139_24550	COG2807	transmembrane transport
FY139_24555	COG1846	Transcriptional regulator
FY139_24570	COG2814	Major facilitator Superfamily
FY139_24600	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY139_24615	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY139_24620	COG0583	DNA-binding transcription factor activity
FY139_24635	COG0071	Belongs to the small heat shock protein (HSP20) family
FY139_24680	COG3838	Conjugal transfer protein Trbc
FY139_24685	COG3702	type iv secretory pathway
FY139_24690	COG3451	type IV secretory pathway VirB4
FY139_24705	COG3704	protein secretion by the type IV secretion system
FY139_24715	COG3736	Type IV secretory pathway, component VirB8
FY139_24720	COG3504	Conjugal transfer protein
FY139_24725	COG2948	multi-organism process
FY139_24730	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY139_24830	COG3831	ATPase activity
FY139_24845	COG3505	Type IV secretory pathway VirD4
FY139_24865	COG0583	DNA-binding transcription factor activity
FY139_24905	COG0745	RESPONSE REGULATOR receiver
FY139_24945	COG3842	ATPase activity
FY139_24950	COG4208	sulfate ABC transporter
FY139_24955	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY139_24975	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY139_24980	COG1942	4-Oxalocrotonate Tautomerase
FY139_24990	COG3971	2-oxopent-4-enoate hydratase activity
FY139_25000	COG1414	Transcriptional regulator
FY139_25010	COG1137	ATPase activity
FY139_25025	COG4177	L-phenylalanine transmembrane transporter activity
FY139_25045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY139_25050	COG1175	transmembrane transport
FY139_25055	COG0395	ABC-type sugar transport system, permease component
FY139_25065	COG0366	Alpha amylase catalytic
FY139_25070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY139_25075	COG1082	Xylose isomerase domain protein TIM barrel
FY139_25080	COG3842	ATPase activity
FY139_25090	COG1940	carbohydrate kinase activity
FY139_25095	COG0395	ABC-type sugar transport system, permease component
FY139_25105	COG2182	Extracellular solute-binding protein
FY139_25110	COG0673	inositol 2-dehydrogenase activity
FY139_25140	COG1126	abc transporter atp-binding protein
FY139_25145	COG0765	amino acid transport
FY139_25150	COG0765	amino acid transport
FY139_25160	COG4608	Belongs to the ABC transporter superfamily
FY139_25170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_25185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY139_25190	COG0583	DNA-binding transcription factor activity
FY139_25195	COG2423	ornithine cyclodeaminase activity
FY139_25205	COG1957	nucleoside hydrolase
FY139_25225	COG1335	isochorismatase
FY139_25230	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_25275	COG0583	DNA-binding transcription factor activity
FY139_25280	COG1902	pentaerythritol trinitrate reductase activity
FY139_25285	COG0583	DNA-binding transcription factor activity
FY139_25290	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_25300	COG1335	isochorismatase
FY139_25305	COG0583	DNA-binding transcription factor activity
FY139_25315	COG1695	Transcriptional regulator
FY139_25395	COG2207	Transcriptional regulator
FY139_25440	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_25455	COG1802	Transcriptional regulator
FY139_25460	COG3485	protocatechuate 3,4-dioxygenase
FY139_25465	COG3971	2-oxopent-4-enoate hydratase activity
FY139_25480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY139_25485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY139_25500	COG1063	alcohol dehydrogenase
FY139_25510	COG1960	acyl-CoA dehydrogenase activity
FY139_25515	COG1024	Enoyl-CoA hydratase
FY139_25525	COG1012	belongs to the aldehyde dehydrogenase family
FY139_25530	COG0477	Major facilitator Superfamily
FY139_25545	COG3706	GGDEF domain
FY139_25565	COG1846	Transcriptional regulator
FY139_25605	COG1012	belongs to the aldehyde dehydrogenase family
FY139_25615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY139_25625	COG3386	PFAM SMP-30 Gluconolaconase
FY139_25630	COG3622	Belongs to the hyi family
FY139_25635	COG2084	Dehydrogenase
FY139_25660	COG1940	carbohydrate kinase activity
FY139_25665	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY139_25675	COG1129	ABC transporter
FY139_25695	COG0583	DNA-binding transcription factor activity
FY139_25700	COG2271	Major facilitator Superfamily
FY139_25710	COG2272	Belongs to the type-B carboxylesterase lipase family
FY139_25730	COG1129	ABC transporter
FY139_25755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY139_25765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY139_25800	COG0583	DNA-binding transcription factor activity
FY139_25805	COG1414	Transcriptional regulator
FY139_25815	COG4948	Mandelate Racemase Muconate Lactonizing
FY139_25825	COG3842	ATPase activity
FY139_25830	COG1175	transmembrane transport
FY139_25835	COG0395	ABC-type sugar transport system, permease component
FY139_25845	COG0477	Major facilitator Superfamily
FY139_25880	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY139_25900	COG0747	negative chemotaxis
FY139_25910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_25925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY139_25935	COG4215	(ABC) transporter
FY139_25990	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY139_25995	COG0251	oxidation-reduction process
FY139_26000	COG3547	Transposase (IS116 IS110 IS902 family)
FY139_26035	COG1028	Short-chain dehydrogenase reductase Sdr
FY139_26040	COG1335	isochorismatase
FY139_26050	COG1309	transcriptional regulator
FY139_26055	COG4604	ABC transporter, ATP-binding protein
FY139_26060	COG4605	iron ion homeostasis
FY139_26065	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY139_26075	COG2132	Multicopper oxidase
FY139_26080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY139_26085	COG4771	TonB-dependent receptor
FY139_26120	COG1695	Transcriptional regulator
FY139_26155	COG2132	Multicopper oxidase
FY139_26190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY139_26210	COG1192	Involved in chromosome partitioning
FY139_26215	COG1475	DNA binding
FY139_26220	COG0640	Transcriptional regulator
FY139_26225	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY139_26255	COG2211	Major facilitator Superfamily
FY139_26300	COG4974	Belongs to the 'phage' integrase family
FY139_26305	COG1051	belongs to the nudix hydrolase family
FY139_26345	COG1475	DNA binding
FY139_26370	COG2824	Alkylphosphonate utilization operon protein PhnA
FY139_26390	COG1280	lysine exporter protein (LysE YggA)
FY139_26455	COG5489	Protein of unknown function (DUF736)
FY139_26540	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY139_26555	COG0747	negative chemotaxis
FY139_26575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_26580	COG0584	glycerophosphoryl diester phosphodiesterase
FY139_26585	COG0483	inositol monophosphate 1-phosphatase activity
FY139_26650	COG3161	chorismate lyase activity
FY139_26800	COG3436	PFAM IS66 Orf2 family protein
FY139_26895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY139_26925	COG0583	DNA-binding transcription factor activity
FY139_26930	COG0747	negative chemotaxis
FY139_26945	COG0252	asparaginase activity
FY139_26950	COG0583	DNA-binding transcription factor activity
FY139_26970	COG3842	ATPase activity
FY139_26995	COG3701	Conjugal transfer protein
FY139_27000	COG3846	protein secretion by the type IV secretion system
FY139_27010	COG5314	conjugation
FY139_27015	COG3451	type IV secretory pathway VirB4
FY139_27030	COG4962	Type ii secretion system protein e