locus-tag	class	description
FY140_00030	COG1522	sequence-specific DNA binding
FY140_00035	COG1012	belongs to the aldehyde dehydrogenase family
FY140_00040	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY140_00045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY140_00050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY140_00055	COG2423	ornithine cyclodeaminase activity
FY140_00060	COG0006	proline dipeptidase activity
FY140_00065	COG3608	succinylglutamate desuccinylase aspartoacylase
FY140_00070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY140_00075	COG0765	amino acid transport
FY140_00080	COG0765	amino acid transport
FY140_00085	COG1126	abc transporter atp-binding protein
FY140_00095	COG1082	Xylose isomerase domain protein TIM barrel
FY140_00110	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_00115	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_00120	COG1129	ABC transporter
FY140_00150	COG0110	maltose O-acetyltransferase activity
FY140_00155	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY140_00180	COG0488	(ABC) transporter
FY140_00185	COG5265	(ABC) transporter
FY140_00190	COG3181	Tripartite tricarboxylate transporter family receptor
FY140_00205	COG3237	CsbD-like
FY140_00225	COG0395	ABC-type sugar transport system, permease component
FY140_00230	COG3842	ATPase activity
FY140_00240	COG0483	inositol monophosphate 1-phosphatase activity
FY140_00250	COG0405	Gamma-glutamyltransferase
FY140_00255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_00260	COG0601	transmembrane transport
FY140_00265	COG0747	negative chemotaxis
FY140_00270	COG2186	Transcriptional regulator
FY140_00280	COG4948	Mandelate Racemase Muconate Lactonizing
FY140_00285	COG4172	Belongs to the ABC transporter superfamily
FY140_00290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_00295	COG0601	transmembrane transport
FY140_00300	COG0747	negative chemotaxis
FY140_00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_00320	COG2223	nitrite transmembrane transporter activity
FY140_00330	COG3383	formate dehydrogenase (NAD+) activity
FY140_00350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY140_00365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY140_00375	COG0765	amino acid transport
FY140_00380	COG0765	amino acid transport
FY140_00410	COG3938	Belongs to the proline racemase family
FY140_00420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_00430	COG0765	amino acid transport
FY140_00445	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY140_00450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_00460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY140_00465	COG0784	Response regulator, receiver
FY140_00480	COG0842	Transport permease protein
FY140_00485	COG1129	ABC transporter
FY140_00485	COG0842	Transport permease protein
FY140_00490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_00495	COG1486	melibiose metabolic process
FY140_00500	COG4172	Belongs to the ABC transporter superfamily
FY140_00505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_00510	COG0601	transmembrane transport
FY140_00515	COG0747	negative chemotaxis
FY140_00520	COG1486	melibiose metabolic process
FY140_00545	COG1940	carbohydrate kinase activity
FY140_00550	COG2182	Extracellular solute-binding protein
FY140_00555	COG1175	transmembrane transport
FY140_00560	COG0395	ABC-type sugar transport system, permease component
FY140_00565	COG0165	Argininosuccinate lyase
FY140_00570	COG3842	ATPase activity
FY140_00575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_00580	COG3119	arylsulfatase activity
FY140_00590	COG0583	DNA-binding transcription factor activity
FY140_00595	COG1012	belongs to the aldehyde dehydrogenase family
FY140_00640	COG1120	ATPase activity
FY140_00645	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_00650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_00660	COG4774	siderophore transport
FY140_00670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY140_00685	COG5002	protein histidine kinase activity
FY140_00695	COG1566	PFAM secretion protein HlyD family protein
FY140_00710	COG1392	Phosphate transport regulator
FY140_00715	COG0306	phosphate transporter
FY140_00720	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY140_00730	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY140_00740	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_00745	COG3300	MHYT domain
FY140_00745	COG5001	Diguanylate cyclase
FY140_00765	COG2186	Transcriptional regulator
FY140_00770	COG0601	transmembrane transport
FY140_00775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_00780	COG0444	Belongs to the ABC transporter superfamily
FY140_00785	COG4608	Belongs to the ABC transporter superfamily
FY140_00790	COG0210	DNA helicase
FY140_00815	COG0438	transferase activity, transferring glycosyl groups
FY140_00820	COG1132	(ABC) transporter
FY140_00840	COG2942	2-epimerase
FY140_00850	COG0583	DNA-binding transcription factor activity
FY140_00855	COG0667	Aldo Keto reductase
FY140_00860	COG0385	Bile acid
FY140_00880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY140_00935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY140_00950	COG0300	oxidoreductase activity
FY140_00955	COG0483	inositol monophosphate 1-phosphatase activity
FY140_00960	COG0584	glycerophosphoryl diester phosphodiesterase
FY140_00970	COG4149	molybdate abc transporter
FY140_00975	COG3842	ATPase activity
FY140_00995	COG3712	iron ion homeostasis
FY140_01000	COG4774	siderophore transport
FY140_01005	COG2814	Major facilitator Superfamily
FY140_01025	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY140_01035	COG3842	ATPase activity
FY140_01040	COG1175	transmembrane transport
FY140_01045	COG0395	ABC-type sugar transport system, permease component
FY140_01050	COG1609	Transcriptional regulator
FY140_01060	COG0673	inositol 2-dehydrogenase activity
FY140_01065	COG1082	Xylose isomerase domain protein TIM barrel
FY140_01080	COG1609	Transcriptional regulator
FY140_01085	COG0183	Belongs to the thiolase family
FY140_01090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY140_01100	COG1414	Transcriptional regulator
FY140_01115	COG0583	DNA-binding transcription factor activity
FY140_01125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY140_01130	COG3485	protocatechuate 3,4-dioxygenase
FY140_01135	COG3485	protocatechuate 3,4-dioxygenase
FY140_01145	COG0765	amino acid transport
FY140_01150	COG0765	amino acid transport
FY140_01155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY140_01160	COG1126	abc transporter atp-binding protein
FY140_01165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY140_01170	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY140_01185	COG4172	Belongs to the ABC transporter superfamily
FY140_01190	COG0747	negative chemotaxis
FY140_01200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_01215	COG0683	leucine binding
FY140_01250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_01255	COG3962	Belongs to the TPP enzyme family
FY140_01265	COG3718	enzyme involved in inositol metabolism
FY140_01275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY140_01280	COG1609	Transcriptional regulator
FY140_01285	COG1846	Transcriptional regulator
FY140_01295	COG0523	cobalamin synthesis protein
FY140_01330	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY140_01350	COG0800	Aldolase
FY140_01355	COG2954	triphosphatase activity
FY140_01365	COG1054	Belongs to the UPF0176 family
FY140_01370	COG3300	MHYT domain
FY140_01370	COG5001	Diguanylate cyclase
FY140_01380	COG2011	ABC-type metal ion transport system permease component
FY140_01385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY140_01390	COG0778	Nitroreductase
FY140_01400	COG5001	Diguanylate cyclase
FY140_01415	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY140_01420	COG2894	cell division
FY140_01425	COG0850	regulation of cytokinetic process
FY140_01430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY140_01435	COG2186	Transcriptional regulator
FY140_01440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY140_01450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY140_01455	COG1063	alcohol dehydrogenase
FY140_01460	COG1312	Catalyzes the dehydration of D-mannonate
FY140_01480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY140_01485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY140_01485	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY140_01490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_01505	COG0625	glutathione transferase activity
FY140_01515	COG1921	L-seryl-tRNASec selenium transferase activity
FY140_01530	COG3964	amidohydrolase
FY140_01540	COG0601	transmembrane transport
FY140_01545	COG0747	negative chemotaxis
FY140_01550	COG0438	transferase activity, transferring glycosyl groups
FY140_01585	COG4989	oxidoreductase activity
FY140_01600	COG3842	ATPase activity
FY140_01605	COG1653	transport
FY140_01610	COG1175	transmembrane transport
FY140_01615	COG0395	ABC-type sugar transport system, permease component
FY140_01620	COG1501	Belongs to the glycosyl hydrolase 31 family
FY140_01630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_01635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY140_01640	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY140_01645	COG0352	thiamine-phosphate diphosphorylase activity
FY140_01650	COG0351	phosphomethylpyrimidine kinase
FY140_01655	COG1522	sequence-specific DNA binding
FY140_01660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY140_01665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_01680	COG2204	response regulator
FY140_01685	COG4191	Histidine kinase
FY140_01690	COG1301	dicarboxylic acid transport
FY140_01700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY140_01705	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_01715	COG1473	amidohydrolase
FY140_01735	COG1215	transferase activity, transferring glycosyl groups
FY140_01745	COG2942	2-epimerase
FY140_01770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY140_01780	COG2197	response regulator
FY140_01810	COG3307	-O-antigen
FY140_01815	COG1596	polysaccharide export
FY140_01820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY140_01830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY140_01835	COG1376	ErfK ybiS ycfS ynhG family protein
FY140_01845	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_01855	COG2094	Belongs to the DNA glycosylase MPG family
FY140_01870	COG1609	Transcriptional regulator
FY140_01875	COG1653	transport
FY140_01890	COG3842	ATPase activity
FY140_01900	COG0673	inositol 2-dehydrogenase activity
FY140_01905	COG0602	queuosine metabolic process
FY140_01910	COG0720	synthase
FY140_01915	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY140_01920	COG0673	inositol 2-dehydrogenase activity
FY140_01935	COG0395	ABC-type sugar transport system, permease component
FY140_01940	COG1175	transmembrane transport
FY140_01960	COG0281	malic enzyme
FY140_01960	COG0280	phosphate acetyltransferase
FY140_01980	COG0765	amino acid transport
FY140_01985	COG1126	abc transporter atp-binding protein
FY140_01990	COG2079	MmgE PrpD family protein
FY140_01995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_02020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY140_02030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY140_02035	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY140_02040	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_02045	COG1129	ABC transporter
FY140_02055	COG1473	amidohydrolase
FY140_02070	COG4172	Belongs to the ABC transporter superfamily
FY140_02080	COG0601	transmembrane transport
FY140_02085	COG0583	DNA-binding transcription factor activity
FY140_02090	COG1446	asparaginase
FY140_02105	COG0747	negative chemotaxis
FY140_02125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_02130	COG0601	transmembrane transport
FY140_02135	COG2197	response regulator
FY140_02140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY140_02145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY140_02160	COG0395	ABC-type sugar transport system, permease component
FY140_02165	COG1175	transmembrane transport
FY140_02175	COG0673	inositol 2-dehydrogenase activity
FY140_02180	COG0673	inositol 2-dehydrogenase activity
FY140_02200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_02205	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY140_02225	COG1595	DNA-templated transcription, initiation
FY140_02230	COG1120	ATPase activity
FY140_02235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_02250	COG2226	methyltransferase
FY140_02260	COG1120	ATPase activity
FY140_02265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_02285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY140_02310	COG1012	belongs to the aldehyde dehydrogenase family
FY140_02315	COG0473	3-isopropylmalate dehydrogenase activity
FY140_02320	COG1012	belongs to the aldehyde dehydrogenase family
FY140_02325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_02365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_02370	COG4172	Belongs to the ABC transporter superfamily
FY140_02375	COG1522	sequence-specific DNA binding
FY140_02400	COG0583	DNA-binding transcription factor activity
FY140_02410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY140_02415	COG1126	abc transporter atp-binding protein
FY140_02425	COG1473	amidohydrolase
FY140_02430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02440	COG1959	2 iron, 2 sulfur cluster binding
FY140_02450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY140_02455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02510	COG0667	Aldo Keto reductase
FY140_02520	COG0583	DNA-binding transcription factor activity
FY140_02525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02530	COG4166	transmembrane transport
FY140_02540	COG0747	negative chemotaxis
FY140_02545	COG1473	amidohydrolase
FY140_02550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02555	COG0702	epimerase
FY140_02565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_02590	COG4608	Belongs to the ABC transporter superfamily
FY140_02595	COG0444	Belongs to the ABC transporter superfamily
FY140_02605	COG0601	transmembrane transport
FY140_02615	COG2186	Transcriptional regulator
FY140_02630	COG0300	oxidoreductase activity
FY140_02645	COG0640	Transcriptional regulator
FY140_02655	COG2391	methyltransferase activity
FY140_02660	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY140_02670	COG0022	dehydrogenase e1 component
FY140_02680	COG1960	acyl-CoA dehydrogenase activity
FY140_02685	COG0183	Belongs to the thiolase family
FY140_02695	COG1960	acyl-CoA dehydrogenase activity
FY140_02700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY140_02720	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY140_02725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY140_02730	COG4952	isomerase
FY140_02735	COG3347	Dehydrogenase
FY140_02735	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_02740	COG1349	DNA-binding transcription factor activity
FY140_02750	COG1129	ABC transporter
FY140_02755	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_02765	COG3254	rhamnose metabolic process
FY140_02780	COG2264	protein methyltransferase activity
FY140_02785	COG5001	Diguanylate cyclase
FY140_02800	COG4335	DNA alkylation repair
FY140_02805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY140_02810	COG4208	sulfate ABC transporter
FY140_02825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY140_02840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY140_02850	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY140_02860	COG1040	competence protein
FY140_02865	COG2226	methyltransferase
FY140_02880	COG0494	nUDIX hydrolase
FY140_02890	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY140_02895	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY140_02900	COG0653	protein targeting
FY140_02905	COG0697	spore germination
FY140_02990	COG2244	polysaccharide biosynthetic process
FY140_03005	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY140_03015	COG3206	protein involved in exopolysaccharide biosynthesis
FY140_03015	COG0489	protein tyrosine kinase activity
FY140_03035	COG0438	transferase activity, transferring glycosyl groups
FY140_03040	COG0438	transferase activity, transferring glycosyl groups
FY140_03055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY140_03060	COG2273	Hydrolase Family 16
FY140_03060	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY140_03105	COG1396	sequence-specific DNA binding
FY140_03115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY140_03120	COG1129	ABC transporter
FY140_03125	COG4214	carbohydrate transport
FY140_03130	COG4213	ABC transporter substrate-binding protein
FY140_03145	COG0640	Transcriptional regulator
FY140_03155	COG0346	lactoylglutathione lyase activity
FY140_03160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY140_03160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY140_03165	COG4770	biotin carboxylase activity
FY140_03175	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY140_03185	COG0625	glutathione transferase activity
FY140_03190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY140_03195	COG1396	sequence-specific DNA binding
FY140_03195	COG3800	Transcriptional regulator
FY140_03205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY140_03215	COG0300	oxidoreductase activity
FY140_03225	COG2096	Adenosyltransferase
FY140_03235	COG2086	electron transfer activity
FY140_03245	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY140_03255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY140_03260	COG0165	Argininosuccinate lyase
FY140_03295	COG2884	Cell division ATP-binding protein ftsE
FY140_03315	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY140_03325	COG0287	Prephenate dehydrogenase
FY140_03330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY140_03335	COG2226	methyltransferase
FY140_03340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY140_03355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY140_03360	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY140_03400	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY140_03405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY140_03415	COG4974	Belongs to the 'phage' integrase family
FY140_03420	COG0825	malonyl-CoA metabolic process
FY140_03425	COG3034	peptidoglycan biosynthetic process
FY140_03430	COG0425	Belongs to the sulfur carrier protein TusA family
FY140_03430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY140_03435	COG0523	cobalamin synthesis protein
FY140_03440	COG1686	Belongs to the peptidase S11 family
FY140_03445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY140_03485	COG1473	amidohydrolase
FY140_03495	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY140_03500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY140_03510	COG2706	6-phosphogluconolactonase activity
FY140_03535	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FY140_03570	COG0673	inositol 2-dehydrogenase activity
FY140_03580	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_03590	COG3962	Belongs to the TPP enzyme family
FY140_03595	COG0673	inositol 2-dehydrogenase activity
FY140_03600	COG1012	belongs to the aldehyde dehydrogenase family
FY140_03610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY140_03630	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_03635	COG1129	ABC transporter
FY140_03650	COG4953	penicillin-binding protein 1C
FY140_03655	COG2373	Large extracellular alpha-helical protein
FY140_03660	COG2835	tetraacyldisaccharide 4'-kinase activity
FY140_03695	COG0482	sulfurtransferase activity
FY140_03710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY140_03725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY140_03730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY140_03735	COG0037	tRNA processing
FY140_03745	COG2885	chlorophyll binding
FY140_03750	COG0823	Involved in the tonB-independent uptake of proteins
FY140_03770	COG0824	Thioesterase
FY140_03780	COG0494	nUDIX hydrolase
FY140_03795	COG2255	four-way junction helicase activity
FY140_03800	COG0632	four-way junction helicase activity
FY140_03805	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY140_03810	COG0840	transmembrane signaling receptor activity
FY140_03815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_03820	COG0217	transcriptional regulatory protein
FY140_03835	COG1692	metallophosphoesterase
FY140_03845	COG1253	flavin adenine dinucleotide binding
FY140_03880	COG0126	phosphoglycerate kinase activity
FY140_03885	COG3588	fructose-bisphosphate aldolase
FY140_03890	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY140_03890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY140_03895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY140_03905	COG1414	Transcriptional regulator
FY140_03920	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_03960	COG0254	rRNA binding
FY140_03965	COG1132	(ABC) transporter
FY140_03985	COG0483	inositol monophosphate 1-phosphatase activity
FY140_04015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY140_04020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY140_04025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY140_04030	COG0457	Tetratricopeptide repeat
FY140_04035	COG3750	Belongs to the UPF0335 family
FY140_04055	COG0469	pyruvate kinase activity
FY140_04060	COG3108	Peptidase M15
FY140_04065	COG2204	response regulator
FY140_04070	COG1164	Oligoendopeptidase f
FY140_04075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY140_04085	COG5310	Homospermidine synthase
FY140_04095	COG0737	Belongs to the 5'-nucleotidase family
FY140_04100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY140_04105	COG0330	HflC and HflK could
FY140_04135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY140_04140	COG2951	lytic endotransglycosylase activity
FY140_04155	COG2205	protein histidine kinase activity
FY140_04170	COG0067	glutamate synthase
FY140_04170	COG0069	glutamate synthase activity
FY140_04170	COG0070	glutamate synthase
FY140_04185	COG2205	protein histidine kinase activity
FY140_04190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY140_04195	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY140_04200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY140_04210	COG0252	asparaginase activity
FY140_04220	COG1027	Aspartate ammonia-lyase
FY140_04225	COG2186	Transcriptional regulator
FY140_04255	COG3842	ATPase activity
FY140_04260	COG1177	transmembrane transport
FY140_04280	COG1012	belongs to the aldehyde dehydrogenase family
FY140_04285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_04295	COG2267	carboxylic ester hydrolase activity
FY140_04320	COG4176	ABC-type proline glycine betaine transport system permease component
FY140_04325	COG4175	Glycine betaine
FY140_04325	COG0517	IMP dehydrogenase activity
FY140_04330	COG2986	histidine ammonia-lyase
FY140_04345	COG0174	glutamine synthetase
FY140_04350	COG0069	glutamate synthase activity
FY140_04355	COG2218	PFAM glutamate synthase alpha subunit domain protein
FY140_04360	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY140_04370	COG4977	sequence-specific DNA binding
FY140_04375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_04380	COG4311	Sarcosine oxidase, delta subunit
FY140_04385	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY140_04385	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY140_04395	COG1609	Transcriptional regulator
FY140_04415	COG1082	Xylose isomerase domain protein TIM barrel
FY140_04420	COG0673	inositol 2-dehydrogenase activity
FY140_04425	COG1082	Xylose isomerase domain protein TIM barrel
FY140_04430	COG1082	Xylose isomerase domain protein TIM barrel
FY140_04490	COG3586	endonuclease activity
FY140_04505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FY140_04510	COG1451	nucleotide metabolic process
FY140_04525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY140_04555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_04565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_04570	COG0601	transmembrane transport
FY140_04575	COG0747	negative chemotaxis
FY140_04585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY140_04590	COG1454	alcohol dehydrogenase
FY140_04630	COG2307	Protein conserved in bacteria
FY140_04630	COG2308	Evidence 4 Homologs of previously reported genes of
FY140_04645	COG0488	(ABC) transporter
FY140_04650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY140_04655	COG2186	Transcriptional regulator
FY140_04670	COG1175	transmembrane transport
FY140_04675	COG0395	ABC-type sugar transport system, permease component
FY140_04685	COG3842	ATPase activity
FY140_04710	COG1304	FMN binding
FY140_04725	COG1063	alcohol dehydrogenase
FY140_04730	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY140_04735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY140_04745	COG0765	amino acid transport
FY140_04750	COG0765	amino acid transport
FY140_04755	COG4221	oxidoreductase activity
FY140_04760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY140_04765	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_04770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY140_04785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY140_04800	COG0697	spore germination
FY140_04805	COG0697	spore germination
FY140_04810	COG0511	ligase activity, forming carbon-carbon bonds
FY140_04815	COG0439	Biotin carboxylase
FY140_04825	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY140_04830	COG1984	allophanate hydrolase subunit 2
FY140_04835	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY140_04840	COG3842	ATPase activity
FY140_04850	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY140_04860	COG0436	Aminotransferase
FY140_04865	COG4221	oxidoreductase activity
FY140_04875	COG0840	transmembrane signaling receptor activity
FY140_04880	COG1070	Carbohydrate kinase
FY140_04885	COG1830	Aldolase
FY140_04890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY140_04895	COG0667	Aldo Keto reductase
FY140_04905	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_04910	COG1129	ABC transporter
FY140_04915	COG1879	ABC-type sugar transport system periplasmic component
FY140_04920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY140_04930	COG1609	Transcriptional regulator
FY140_04935	COG1053	succinate dehydrogenase
FY140_04935	COG3976	FMN-binding domain protein
FY140_04945	COG1175	transmembrane transport
FY140_04950	COG0395	ABC-type sugar transport system, permease component
FY140_04955	COG3842	ATPase activity
FY140_04965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FY140_04980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_04995	COG0601	transmembrane transport
FY140_05000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_05010	COG4172	Belongs to the ABC transporter superfamily
FY140_05015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_05020	COG0601	transmembrane transport
FY140_05055	COG0071	Belongs to the small heat shock protein (HSP20) family
FY140_05070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY140_05085	COG0395	ABC-type sugar transport system, permease component
FY140_05100	COG3842	ATPase activity
FY140_05115	COG1648	precorrin-2 dehydrogenase activity
FY140_05115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY140_05120	COG0243	molybdopterin cofactor binding
FY140_05130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY140_05135	COG1116	anion transmembrane transporter activity
FY140_05140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_05145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY140_05150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY140_05155	COG3707	response regulator
FY140_05160	COG1802	Transcriptional regulator
FY140_05165	COG1914	H( )-stimulated, divalent metal cation uptake system
FY140_05170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY140_05175	COG4336	lyase activity
FY140_05180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY140_05185	COG4770	biotin carboxylase activity
FY140_05190	COG0366	Alpha amylase catalytic
FY140_05200	COG4771	TonB-dependent receptor
FY140_05225	COG1414	Transcriptional regulator
FY140_05230	COG1475	DNA binding
FY140_05235	COG1192	Involved in chromosome partitioning
FY140_05265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY140_05275	COG2986	histidine ammonia-lyase
FY140_05280	COG1228	amidohydrolase
FY140_05285	COG0402	S-adenosylhomocysteine deaminase activity
FY140_05325	COG1609	Transcriptional regulator
FY140_05335	COG4211	Belongs to the binding-protein-dependent transport system permease family
FY140_05350	COG0673	inositol 2-dehydrogenase activity
FY140_05355	COG1737	Transcriptional regulator
FY140_05360	COG1309	transcriptional regulator
FY140_05365	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_05385	COG1846	Transcriptional regulator
FY140_05390	COG0583	DNA-binding transcription factor activity
FY140_05395	COG2828	Protein conserved in bacteria
FY140_05410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_05430	COG0840	transmembrane signaling receptor activity
FY140_05465	COG1215	transferase activity, transferring glycosyl groups
FY140_05495	COG0583	DNA-binding transcription factor activity
FY140_05500	COG0346	lactoylglutathione lyase activity
FY140_05515	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY140_05540	COG1309	transcriptional regulator
FY140_05545	COG2268	Band 7 protein
FY140_05555	COG1842	Phage shock protein A
FY140_05565	COG0583	DNA-binding transcription factor activity
FY140_05570	COG0477	Major facilitator Superfamily
FY140_05590	COG4774	siderophore transport
FY140_05610	COG5002	protein histidine kinase activity
FY140_05610	COG3850	Histidine kinase
FY140_05615	COG0745	RESPONSE REGULATOR receiver
FY140_05620	COG0671	phosphoesterase, PA-phosphatase related
FY140_05670	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY140_05680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY140_05685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY140_05690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY140_05705	COG0010	Belongs to the arginase family
FY140_05715	COG0697	spore germination
FY140_05720	COG0673	inositol 2-dehydrogenase activity
FY140_05745	COG0477	Major facilitator Superfamily
FY140_05760	COG2194	sulfuric ester hydrolase activity
FY140_05770	COG0583	DNA-binding transcription factor activity
FY140_05775	COG4774	siderophore transport
FY140_05790	COG1120	ATPase activity
FY140_05800	COG3474	cytochrome
FY140_05805	COG2137	regulation of response to DNA damage stimulus
FY140_05810	COG3386	PFAM SMP-30 Gluconolaconase
FY140_05820	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_05825	COG1129	ABC transporter
FY140_05830	COG1879	ABC-type sugar transport system periplasmic component
FY140_05835	COG4585	Histidine kinase
FY140_05840	COG2197	response regulator
FY140_05850	COG2133	pyrroloquinoline quinone binding
FY140_05860	COG0500	methyltransferase
FY140_05865	COG0564	pseudouridine synthase activity
FY140_05885	COG4176	ABC-type proline glycine betaine transport system permease component
FY140_05895	COG0784	Response regulator, receiver
FY140_05895	COG4191	Histidine kinase
FY140_05905	COG3206	protein involved in exopolysaccharide biosynthesis
FY140_05905	COG0489	protein tyrosine kinase activity
FY140_05910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY140_05915	COG1215	transferase activity, transferring glycosyl groups
FY140_05920	COG1215	transferase activity, transferring glycosyl groups
FY140_05925	COG1215	transferase activity, transferring glycosyl groups
FY140_05930	COG0438	transferase activity, transferring glycosyl groups
FY140_05935	COG2273	Hydrolase Family 16
FY140_05940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY140_05945	COG2244	polysaccharide biosynthetic process
FY140_05950	COG0463	Glycosyl transferase, family 2
FY140_05955	COG2327	Polysaccharide pyruvyl transferase
FY140_05960	COG1215	transferase activity, transferring glycosyl groups
FY140_05980	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY140_05985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_06000	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY140_06000	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY140_06025	COG0033	Phosphoglucomutase
FY140_06030	COG0297	glycogen (starch) synthase activity
FY140_06035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY140_06040	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY140_06045	COG0058	SHG alpha-glucan phosphorylase activity
FY140_06055	COG1794	racemase activity, acting on amino acids and derivatives
FY140_06060	COG1522	sequence-specific DNA binding
FY140_06070	COG2084	Dehydrogenase
FY140_06075	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_06080	COG1063	alcohol dehydrogenase
FY140_06090	COG4988	ABC transporter
FY140_06095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY140_06105	COG1294	oxidase, subunit
FY140_06135	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY140_06140	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY140_06170	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY140_06175	COG0539	negative regulation of cytoplasmic translation
FY140_06205	COG4221	oxidoreductase activity
FY140_06210	COG0006	proline dipeptidase activity
FY140_06215	COG0747	negative chemotaxis
FY140_06220	COG0601	transmembrane transport
FY140_06225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_06230	COG0444	Belongs to the ABC transporter superfamily
FY140_06235	COG4608	Belongs to the ABC transporter superfamily
FY140_06240	COG0246	Mannitol dehydrogenase
FY140_06255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_06300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY140_06305	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_06320	COG4993	Dehydrogenase
FY140_06325	COG3685	Protein conserved in bacteria
FY140_06330	COG1285	pathogenesis
FY140_06335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_06355	COG0693	protein deglycase activity
FY140_06375	COG0189	ligase activity
FY140_06380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY140_06385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY140_06395	COG0435	Glutathione S-transferase
FY140_06400	COG0583	DNA-binding transcription factor activity
FY140_06405	COG1012	belongs to the aldehyde dehydrogenase family
FY140_06410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY140_06415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_06420	COG1116	anion transmembrane transporter activity
FY140_06430	COG1522	sequence-specific DNA binding
FY140_06445	COG0784	Response regulator, receiver
FY140_06455	COG3920	Histidine kinase
FY140_06465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY140_06480	COG0019	diaminopimelate decarboxylase activity
FY140_06495	COG0527	aspartate kinase activity
FY140_06505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY140_06510	COG2890	protein-(glutamine-N5) methyltransferase activity
FY140_06520	COG0542	response to heat
FY140_06525	COG0741	lytic transglycosylase activity
FY140_06525	COG0739	heme binding
FY140_06525	COG1196	nuclear chromosome segregation
FY140_06625	COG1475	DNA binding
FY140_06670	COG0840	transmembrane signaling receptor activity
FY140_06680	COG3300	MHYT domain
FY140_06680	COG5001	Diguanylate cyclase
FY140_06695	COG0835	chemotaxis
FY140_06700	COG0840	transmembrane signaling receptor activity
FY140_06705	COG0629	single-stranded DNA binding
FY140_06740	COG1192	Involved in chromosome partitioning
FY140_06765	COG0741	lytic transglycosylase activity
FY140_06790	COG4962	Type ii secretion system protein e
FY140_06805	COG3451	type IV secretory pathway VirB4
FY140_06820	COG3846	protein secretion by the type IV secretion system
FY140_06825	COG3701	Conjugal transfer protein
FY140_06845	COG0583	DNA-binding transcription factor activity
FY140_06920	COG3485	protocatechuate 3,4-dioxygenase
FY140_06940	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_06945	COG2814	Major facilitator Superfamily
FY140_06955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FY140_06975	COG0438	transferase activity, transferring glycosyl groups
FY140_06980	COG2144	transferase activity, transferring acyl groups
FY140_07005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY140_07030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY140_07035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY140_07060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY140_07120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_07125	COG0577	efflux transmembrane transporter activity
FY140_07125	COG1136	(ABC) transporter
FY140_07135	COG1733	regulation of RNA biosynthetic process
FY140_07150	COG0395	ABC-type sugar transport system, permease component
FY140_07165	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FY140_07185	COG1929	Belongs to the glycerate kinase type-1 family
FY140_07220	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY140_07235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_07245	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_07260	COG1309	transcriptional regulator
FY140_07265	COG2226	methyltransferase
FY140_07290	COG0753	catalase activity
FY140_07295	COG3685	Protein conserved in bacteria
FY140_07355	COG1573	uracil-dna glycosylase
FY140_07410	COG0583	DNA-binding transcription factor activity
FY140_07415	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY140_07435	COG1984	allophanate hydrolase subunit 2
FY140_07440	COG1879	ABC-type sugar transport system periplasmic component
FY140_07445	COG1129	ABC transporter
FY140_07450	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_07455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY140_07470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY140_07480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY140_07485	COG1012	belongs to the aldehyde dehydrogenase family
FY140_07490	COG0746	molybdenum cofactor guanylyltransferase activity
FY140_07500	COG2376	Dihydroxyacetone kinase
FY140_07505	COG1522	sequence-specific DNA binding
FY140_07525	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY140_07530	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY140_07550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_07565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_07575	COG0747	negative chemotaxis
FY140_07585	COG0277	FAD linked oxidase domain protein
FY140_07610	COG0583	DNA-binding transcription factor activity
FY140_07630	COG0395	ABC-type sugar transport system, permease component
FY140_07635	COG3842	ATPase activity
FY140_07645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_07650	COG1846	Transcriptional regulator
FY140_07650	COG1940	carbohydrate kinase activity
FY140_07660	COG3842	ATPase activity
FY140_07665	COG1177	transmembrane transport
FY140_07695	COG3842	ATPase activity
FY140_07705	COG1177	transmembrane transport
FY140_07710	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY140_07725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY140_07750	COG0583	DNA-binding transcription factor activity
FY140_07765	COG1335	isochorismatase
FY140_07780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY140_07785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY140_07805	COG3938	Belongs to the proline racemase family
FY140_07810	COG4176	ABC-type proline glycine betaine transport system permease component
FY140_07815	COG4176	ABC-type proline glycine betaine transport system permease component
FY140_07820	COG3448	diguanylate cyclase activity
FY140_07820	COG4175	Glycine betaine
FY140_07830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_07835	COG1012	belongs to the aldehyde dehydrogenase family
FY140_07840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_07865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY140_07865	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY140_07875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY140_07880	COG1760	l-serine dehydratase
FY140_07900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY140_07925	COG1309	transcriptional regulator
FY140_07935	COG1063	alcohol dehydrogenase
FY140_07945	COG1879	ABC-type sugar transport system periplasmic component
FY140_07955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_07965	COG1069	ribulokinase activity
FY140_08110	COG5001	Diguanylate cyclase
FY140_08110	COG3300	MHYT domain
FY140_08115	COG0483	inositol monophosphate 1-phosphatase activity
FY140_08140	COG3842	ATPase activity
FY140_08145	COG0395	ABC-type sugar transport system, permease component
FY140_08150	COG1175	transmembrane transport
FY140_08155	COG1653	transport
FY140_08165	COG0673	inositol 2-dehydrogenase activity
FY140_08170	COG1609	Transcriptional regulator
FY140_08185	COG0583	DNA-binding transcription factor activity
FY140_08195	COG1879	ABC-type sugar transport system periplasmic component
FY140_08200	COG1129	ABC transporter
FY140_08205	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_08210	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_08215	COG1609	Transcriptional regulator
FY140_08225	COG0673	inositol 2-dehydrogenase activity
FY140_08285	COG0714	Associated with various cellular activities
FY140_08290	COG3256	nitric oxide reductase
FY140_08315	COG0163	prenyltransferase activity
FY140_08320	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY140_08325	COG3189	MarR family transcriptional regulator
FY140_08335	COG0826	peptidase U32
FY140_08370	COG4459	periplasmic nitrate reductase
FY140_08385	COG0243	molybdopterin cofactor binding
FY140_08395	COG3005	denitrification pathway
FY140_08400	COG0583	DNA-binding transcription factor activity
FY140_08410	COG2188	Transcriptional regulator
FY140_08415	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_08420	COG0673	inositol 2-dehydrogenase activity
FY140_08435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FY140_08445	COG1129	ABC transporter
FY140_08460	COG2390	Transcriptional regulator
FY140_08465	COG3684	Belongs to the aldolase LacD family
FY140_08475	COG1012	belongs to the aldehyde dehydrogenase family
FY140_08480	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY140_08485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_08500	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_08505	COG1535	isochorismatase
FY140_08505	COG3433	isochorismatase activity
FY140_08510	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY140_08515	COG1169	isochorismate synthase
FY140_08525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY140_08525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY140_08530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY140_08540	COG2375	cellular response to nickel ion
FY140_08550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_08555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_08560	COG1120	ATPase activity
FY140_08565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_08575	COG1629	transport
FY140_08575	COG4774	siderophore transport
FY140_08580	COG1960	acyl-CoA dehydrogenase activity
FY140_08585	COG0583	DNA-binding transcription factor activity
FY140_08590	COG1609	Transcriptional regulator
FY140_08610	COG3842	ATPase activity
FY140_08620	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY140_08625	COG0583	DNA-binding transcription factor activity
FY140_08630	COG2814	Major facilitator Superfamily
FY140_08635	COG1473	amidohydrolase
FY140_08650	COG0747	negative chemotaxis
FY140_08655	COG0601	transmembrane transport
FY140_08660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_08665	COG0444	Belongs to the ABC transporter superfamily
FY140_08675	COG0583	DNA-binding transcription factor activity
FY140_08680	COG0747	negative chemotaxis
FY140_08690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_08695	COG0154	amidase activity
FY140_08700	COG0693	protein deglycase activity
FY140_08710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_08715	COG0601	transmembrane transport
FY140_08725	COG1473	amidohydrolase
FY140_08730	COG4172	Belongs to the ABC transporter superfamily
FY140_08735	COG2390	Transcriptional regulator
FY140_08745	COG1175	transmembrane transport
FY140_08750	COG0395	ABC-type sugar transport system, permease component
FY140_08770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY140_08805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY140_08825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY140_08830	COG1414	Transcriptional regulator
FY140_08835	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_08845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY140_08850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY140_08855	COG1121	(ABC) transporter
FY140_08860	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY140_08870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY140_08875	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY140_08880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY140_08885	COG3273	potassium ion transport
FY140_08885	COG0471	metal ion transport
FY140_08895	COG1253	flavin adenine dinucleotide binding
FY140_08900	COG1309	transcriptional regulator
FY140_08925	COG1609	Transcriptional regulator
FY140_08930	COG1070	Carbohydrate kinase
FY140_08935	COG2115	Belongs to the xylose isomerase family
FY140_08950	COG0673	inositol 2-dehydrogenase activity
FY140_08960	COG1653	transport
FY140_08965	COG1175	transmembrane transport
FY140_08970	COG0395	ABC-type sugar transport system, permease component
FY140_08975	COG3842	ATPase activity
FY140_08985	COG0673	inositol 2-dehydrogenase activity
FY140_09010	COG0587	DNA-directed DNA polymerase activity
FY140_09025	COG2186	Transcriptional regulator
FY140_09030	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_09035	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_09040	COG1129	ABC transporter
FY140_09045	COG1879	ABC-type sugar transport system periplasmic component
FY140_09050	COG0129	dihydroxy-acid dehydratase activity
FY140_09060	COG0346	lactoylglutathione lyase activity
FY140_09075	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY140_09080	COG4608	Belongs to the ABC transporter superfamily
FY140_09085	COG0444	Belongs to the ABC transporter superfamily
FY140_09090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_09095	COG0601	transmembrane transport
FY140_09100	COG0747	negative chemotaxis
FY140_09110	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY140_09125	COG3257	ureidoglycine aminohydrolase activity
FY140_09135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_09150	COG1129	ABC transporter
FY140_09155	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_09160	COG1879	ABC-type sugar transport system periplasmic component
FY140_09165	COG0583	DNA-binding transcription factor activity
FY140_09190	COG3047	cAMP biosynthetic process
FY140_09200	COG3842	ATPase activity
FY140_09205	COG0395	ABC-type sugar transport system, permease component
FY140_09210	COG1175	transmembrane transport
FY140_09215	COG1653	transport
FY140_09220	COG0523	cobalamin synthesis protein
FY140_09235	COG0523	cobalamin synthesis protein
FY140_09240	COG1121	(ABC) transporter
FY140_09250	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY140_09255	COG0328	RNA-DNA hybrid ribonuclease activity
FY140_09265	COG0626	cystathionine gamma-synthase activity
FY140_09270	COG2182	Extracellular solute-binding protein
FY140_09275	COG1175	transmembrane transport
FY140_09280	COG0395	ABC-type sugar transport system, permease component
FY140_09295	COG0395	ABC-type sugar transport system, permease component
FY140_09300	COG1175	transmembrane transport
FY140_09305	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY140_09310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_09320	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_09325	COG1063	alcohol dehydrogenase
FY140_09330	COG1609	Transcriptional regulator
FY140_09345	COG2084	Dehydrogenase
FY140_09350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY140_09360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY140_09365	COG0583	DNA-binding transcription factor activity
FY140_09370	COG2223	nitrite transmembrane transporter activity
FY140_09405	COG0667	Aldo Keto reductase
FY140_09420	COG2186	Transcriptional regulator
FY140_09425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY140_09430	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY140_09435	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_09440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_09445	COG4948	Mandelate Racemase Muconate Lactonizing
FY140_09450	COG3618	amidohydrolase
FY140_09455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY140_09475	COG1175	transmembrane transport
FY140_09480	COG0395	ABC-type sugar transport system, permease component
FY140_09485	COG3842	ATPase activity
FY140_09500	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY140_09525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_09530	COG0577	efflux transmembrane transporter activity
FY140_09530	COG1136	(ABC) transporter
FY140_09535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY140_09560	COG1278	Cold shock
FY140_09565	COG0673	inositol 2-dehydrogenase activity
FY140_09580	COG0673	inositol 2-dehydrogenase activity
FY140_09585	COG1309	transcriptional regulator
FY140_09590	COG1653	transport
FY140_09595	COG1175	transmembrane transport
FY140_09600	COG0395	ABC-type sugar transport system, permease component
FY140_09605	COG3842	ATPase activity
FY140_09610	COG1082	Xylose isomerase domain protein TIM barrel
FY140_09625	COG1609	Transcriptional regulator
FY140_09655	COG1175	transmembrane transport
FY140_09660	COG0395	ABC-type sugar transport system, permease component
FY140_09665	COG1116	anion transmembrane transporter activity
FY140_09670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_09675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY140_09685	COG3842	ATPase activity
FY140_09700	COG1653	transport
FY140_09735	COG3842	ATPase activity
FY140_09750	COG0395	ABC-type sugar transport system, permease component
FY140_09800	COG2233	PERMEase
FY140_09805	COG0702	epimerase
FY140_09815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY140_09820	COG2140	Oxalate decarboxylase
FY140_09830	COG4566	intracellular signal transduction
FY140_09835	COG4566	intracellular signal transduction
FY140_09845	COG0243	molybdopterin cofactor binding
FY140_09850	COG0783	Belongs to the Dps family
FY140_09865	COG0596	Alpha beta hydrolase
FY140_09875	COG1764	response to oxidative stress
FY140_09890	COG0596	Alpha beta hydrolase
FY140_09920	COG2814	Major facilitator Superfamily
FY140_09945	COG4178	(ABC) transporter
FY140_09980	COG0640	Transcriptional regulator
FY140_10015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FY140_10035	COG1132	(ABC) transporter
FY140_10210	COG4104	PAAR repeat-containing protein
FY140_10210	COG3209	COG3209 Rhs family protein
FY140_10255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY140_10270	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY140_10275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY140_10280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY140_10285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY140_10290	COG1420	regulation of RNA biosynthetic process
FY140_10295	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY140_10300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY140_10305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY140_10315	COG1137	ATPase activity
FY140_10320	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY140_10330	COG0616	signal peptide processing
FY140_10335	COG0776	regulation of translation
FY140_10350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY140_10355	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY140_10370	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY140_10375	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY140_10380	COG0728	peptidoglycan biosynthetic process
FY140_10390	COG0180	Tryptophanyl-tRNA synthetase
FY140_10400	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY140_10405	COG1214	PFAM Peptidase M22, glycoprotease
FY140_10410	COG0456	acetyltransferase
FY140_10425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY140_10430	COG1702	phosphate starvation-inducible protein PhoH
FY140_10435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY140_10445	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY140_10450	COG1396	sequence-specific DNA binding
FY140_10455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY140_10460	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY140_10465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_10475	COG0242	peptide deformylase activity
FY140_10480	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY140_10485	COG0101	tRNA pseudouridine synthase activity
FY140_10495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY140_10500	COG2171	N-acyltransferase activity
FY140_10510	COG0840	transmembrane signaling receptor activity
FY140_10515	COG1957	nucleoside hydrolase
FY140_10520	COG0071	Belongs to the small heat shock protein (HSP20) family
FY140_10545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY140_10555	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY140_10560	COG0706	membrane insertase activity
FY140_10565	COG0594	ribonuclease P activity
FY140_10570	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY140_10575	COG0840	transmembrane signaling receptor activity
FY140_10595	COG3842	ATPase activity
FY140_10600	COG1175	transmembrane transport
FY140_10605	COG0395	ABC-type sugar transport system, permease component
FY140_10620	COG0427	acetyl-CoA hydrolase
FY140_10630	COG3938	Belongs to the proline racemase family
FY140_10635	COG0418	dihydroorotase activity
FY140_10640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY140_10660	COG0166	Belongs to the GPI family
FY140_10665	COG0318	PFAM AMP-dependent synthetase and ligase
FY140_10670	COG3842	ATPase activity
FY140_10675	COG1840	ABC-type Fe3 transport system, periplasmic component
FY140_10680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY140_10685	COG4774	siderophore transport
FY140_10725	COG2326	polyphosphate kinase activity
FY140_10730	COG5002	protein histidine kinase activity
FY140_10735	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY140_10740	COG0573	inorganic phosphate transmembrane transporter activity
FY140_10750	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY140_10755	COG0704	Plays a role in the regulation of phosphate uptake
FY140_10760	COG0745	RESPONSE REGULATOR receiver
FY140_10770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY140_10775	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY140_10785	COG2967	ApaG domain
FY140_10800	COG0717	Belongs to the dCTP deaminase family
FY140_10825	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY140_10875	COG0167	dihydroorotate dehydrogenase activity
FY140_10890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY140_10910	COG1959	2 iron, 2 sulfur cluster binding
FY140_10915	COG1201	RNA secondary structure unwinding
FY140_10945	COG1960	acyl-CoA dehydrogenase activity
FY140_10950	COG0183	Belongs to the thiolase family
FY140_10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY140_10955	COG1024	Enoyl-CoA hydratase
FY140_10985	COG1320	monovalent cation:proton antiporter activity
FY140_10990	COG2212	antiporter activity
FY140_10995	COG1863	multisubunit Na H antiporter MnhE subunit
FY140_11000	COG0651	ATP synthesis coupled electron transport
FY140_11005	COG1006	Multisubunit Na H antiporter MnhC subunit
FY140_11010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY140_11010	COG2111	Na H antiporter
FY140_11020	COG0840	transmembrane signaling receptor activity
FY140_11030	COG0745	RESPONSE REGULATOR receiver
FY140_11035	COG0643	Histidine kinase
FY140_11035	COG2198	Histidine kinase
FY140_11040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY140_11045	COG2201	protein-glutamate methylesterase activity
FY140_11050	COG0745	RESPONSE REGULATOR receiver
FY140_11055	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY140_11065	COG1766	The M ring may be actively involved in energy transduction
FY140_11070	COG2771	luxR family
FY140_11080	COG2972	Histidine kinase
FY140_11080	COG0840	transmembrane signaling receptor activity
FY140_11085	COG2198	Histidine kinase
FY140_11085	COG0784	Response regulator, receiver
FY140_11085	COG2205	protein histidine kinase activity
FY140_11090	COG1970	mechanosensitive ion channel activity
FY140_11095	COG0436	Aminotransferase
FY140_11110	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY140_11115	COG0424	maF-like protein
FY140_11120	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY140_11130	COG5328	Belongs to the UPF0262 family
FY140_11135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY140_11145	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY140_11175	COG1338	Plays a role in the flagellum-specific transport system
FY140_11185	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY140_11195	COG1706	bacterial-type flagellum-dependent cell motility
FY140_11200	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY140_11205	COG4786	Flagellar basal body rod
FY140_11210	COG1677	Flagellar hook-basal body complex protein FliE
FY140_11215	COG1558	bacterial-type flagellum-dependent cell motility
FY140_11220	COG1815	bacterial-type flagellum-dependent cell motility
FY140_11225	COG1280	lysine exporter protein (LysE YggA)
FY140_11235	COG1157	protein secretion by the type III secretion system
FY140_11240	COG4786	Flagellar basal body rod
FY140_11250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY140_11255	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY140_11260	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY140_11265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY140_11270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY140_11290	COG1360	Flagellar Motor Protein
FY140_11320	COG1256	bacterial-type flagellum assembly
FY140_11320	COG4786	Flagellar basal body rod
FY140_11335	COG5443	negative regulation of bacterial-type flagellum assembly
FY140_11340	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY140_11350	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY140_11390	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY140_11395	COG1609	Transcriptional regulator
FY140_11400	COG1653	transport
FY140_11405	COG1175	transmembrane transport
FY140_11410	COG0395	ABC-type sugar transport system, permease component
FY140_11415	COG0366	Alpha amylase catalytic
FY140_11420	COG3842	ATPase activity
FY140_11430	COG3609	addiction module antidote protein, CC2985 family
FY140_11445	COG0129	dihydroxy-acid dehydratase activity
FY140_11450	COG0363	glucosamine-6-phosphate deaminase activity
FY140_11455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY140_11460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_11470	COG2081	HI0933 family
FY140_11490	COG2224	Isocitrate lyase
FY140_11505	COG3842	ATPase activity
FY140_11510	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY140_11515	COG1177	transmembrane transport
FY140_11525	COG2205	protein histidine kinase activity
FY140_11535	COG0248	Ppx GppA phosphatase
FY140_11540	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY140_11545	COG0477	Major facilitator Superfamily
FY140_11575	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY140_11580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY140_11590	COG0142	geranyltranstransferase activity
FY140_11625	COG0752	glycyl-tRNA synthetase alpha subunit
FY140_11630	COG1704	LemA family
FY140_11635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY140_11645	COG0751	glycine-tRNA ligase activity
FY140_11650	COG1683	Conserved Protein
FY140_11655	COG0840	transmembrane signaling receptor activity
FY140_11665	COG0151	Belongs to the GarS family
FY140_11670	COG2183	response to ionizing radiation
FY140_11675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY140_11685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FY140_11700	COG0583	DNA-binding transcription factor activity
FY140_11720	COG0306	phosphate transporter
FY140_11730	COG0561	phosphatase activity
FY140_11735	COG0438	transferase activity, transferring glycosyl groups
FY140_11740	COG2186	Transcriptional regulator
FY140_11750	COG0583	DNA-binding transcription factor activity
FY140_11755	COG0277	FAD linked oxidase domain protein
FY140_11760	COG0277	FAD linked oxidase domain protein
FY140_11765	COG0247	lactate metabolic process
FY140_11775	COG1376	ErfK ybiS ycfS ynhG family protein
FY140_11780	COG2818	Glycosylase
FY140_11790	COG2855	membrane
FY140_11795	COG0583	DNA-binding transcription factor activity
FY140_11825	COG0124	histidyl-tRNA synthetase
FY140_11835	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY140_11840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY140_11845	COG2259	Doxx family
FY140_11855	COG0459	protein refolding
FY140_11860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY140_11870	COG0196	riboflavin kinase activity
FY140_11875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY140_11885	COG0590	tRNA wobble adenosine to inosine editing
FY140_11890	COG1187	pseudouridine synthase activity
FY140_11895	COG0742	ribosomal rna small subunit methyltransferase
FY140_11900	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY140_11905	COG0475	glutathione-regulated potassium exporter activity
FY140_11905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY140_11910	COG0312	modulator of DNA gyrase
FY140_11915	COG0483	inositol monophosphate 1-phosphatase activity
FY140_11925	COG1519	Transferase
FY140_11935	COG1663	tetraacyldisaccharide 4'-kinase activity
FY140_11945	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY140_11950	COG0745	RESPONSE REGULATOR receiver
FY140_11955	COG5001	Diguanylate cyclase
FY140_11955	COG3300	MHYT domain
FY140_11960	COG3386	PFAM SMP-30 Gluconolaconase
FY140_11965	COG0800	Aldolase
FY140_11970	COG3734	2-keto-3-deoxy-galactonokinase
FY140_11975	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_11980	COG1414	Transcriptional regulator
FY140_11985	COG2197	response regulator
FY140_12000	COG0598	Magnesium transport protein CorA
FY140_12005	COG3158	transport of potassium into the cell
FY140_12020	COG0356	it plays a direct role in the translocation of protons across the membrane
FY140_12030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY140_12035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY140_12045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY140_12065	COG0009	L-threonylcarbamoyladenylate synthase
FY140_12075	COG4638	Rieske (2fe-2S)
FY140_12100	COG1960	acyl-CoA dehydrogenase activity
FY140_12115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY140_12125	COG0840	transmembrane signaling receptor activity
FY140_12135	COG1522	sequence-specific DNA binding
FY140_12160	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY140_12165	COG1741	Belongs to the pirin family
FY140_12170	COG1722	exodeoxyribonuclease VII activity
FY140_12175	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY140_12180	COG1268	BioY protein
FY140_12185	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY140_12190	COG1122	ATPase activity
FY140_12195	COG3214	Protein conserved in bacteria
FY140_12205	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY140_12205	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY140_12210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY140_12230	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY140_12245	COG0259	pyridoxamine-phosphate oxidase activity
FY140_12280	COG0312	modulator of DNA gyrase
FY140_12295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY140_12300	COG0109	protoheme IX farnesyltransferase activity
FY140_12305	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY140_12320	COG3346	SURF1 family
FY140_12325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY140_12330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY140_12335	COG0328	RNA-DNA hybrid ribonuclease activity
FY140_12345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY140_12345	COG0678	peroxiredoxin activity
FY140_12355	COG1678	Uncharacterized ACR, COG1678
FY140_12370	COG3300	MHYT domain
FY140_12370	COG5001	Diguanylate cyclase
FY140_12375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY140_12380	COG0612	Peptidase, M16
FY140_12395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY140_12400	COG1802	Transcriptional regulator
FY140_12415	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY140_12420	COG1073	alpha beta
FY140_12430	COG1194	a g-specific adenine glycosylase
FY140_12445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY140_12450	COG1196	nuclear chromosome segregation
FY140_12460	COG2514	catechol 2,3-dioxygenase activity
FY140_12465	COG0574	Belongs to the PEP-utilizing enzyme family
FY140_12465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY140_12480	COG1823	symporter activity
FY140_12510	COG0579	oxidoreductase
FY140_12525	COG2895	sulfate adenylyltransferase (ATP) activity
FY140_12530	COG0175	sulfate reduction
FY140_12535	COG0175	sulfate reduction
FY140_12540	COG1959	2 iron, 2 sulfur cluster binding
FY140_12545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY140_12550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY140_12555	COG4208	sulfate ABC transporter
FY140_12560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY140_12580	COG2199	diguanylate cyclase activity
FY140_12580	COG2200	EAL domain
FY140_12580	COG2203	Gaf domain
FY140_12590	COG1309	transcriptional regulator
FY140_12595	COG1012	belongs to the aldehyde dehydrogenase family
FY140_12600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY140_12645	COG0477	Major facilitator Superfamily
FY140_12665	COG1793	dna ligase
FY140_12690	COG1376	ErfK ybiS ycfS ynhG family protein
FY140_12695	COG1846	Transcriptional regulator
FY140_12700	COG1764	response to oxidative stress
FY140_12715	COG0488	(ABC) transporter
FY140_12745	COG0583	DNA-binding transcription factor activity
FY140_12750	COG4221	oxidoreductase activity
FY140_12760	COG0433	COG0433 Predicted ATPase
FY140_12770	COG1733	regulation of RNA biosynthetic process
FY140_12775	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_12790	COG0656	L-ascorbic acid biosynthetic process
FY140_12795	COG3781	membrane
FY140_12800	COG2378	regulation of single-species biofilm formation
FY140_12810	COG4106	trans-aconitate 2-methyltransferase activity
FY140_12815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY140_12820	COG0840	transmembrane signaling receptor activity
FY140_12825	COG0583	DNA-binding transcription factor activity
FY140_12840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY140_12860	COG3909	cytochrome
FY140_12865	COG2010	Cytochrome c
FY140_12895	COG0789	Transcriptional regulator
FY140_12920	COG0517	IMP dehydrogenase activity
FY140_12920	COG4175	Glycine betaine
FY140_12925	COG4176	ABC-type proline glycine betaine transport system permease component
FY140_12960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY140_12960	COG2169	Transcriptional regulator
FY140_12970	COG2514	catechol 2,3-dioxygenase activity
FY140_12990	COG1272	protein, Hemolysin III
FY140_13005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY140_13010	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY140_13010	COG2111	Na H antiporter
FY140_13015	COG2111	Na H antiporter
FY140_13020	COG1006	Multisubunit Na H antiporter MnhC subunit
FY140_13025	COG0651	ATP synthesis coupled electron transport
FY140_13030	COG1863	multisubunit Na H antiporter MnhE subunit
FY140_13035	COG2212	antiporter activity
FY140_13040	COG1320	monovalent cation:proton antiporter activity
FY140_13045	COG4957	zinc ion binding
FY140_13060	COG2166	iron-sulfur cluster assembly
FY140_13070	COG2205	protein histidine kinase activity
FY140_13120	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY140_13125	COG2983	Belongs to the UPF0260 family
FY140_13135	COG2217	Heavy metal translocating P-type atpase
FY140_13155	COG2337	Toxic component of a toxin-antitoxin (TA) module
FY140_13175	COG2814	Major facilitator Superfamily
FY140_13185	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY140_13240	COG4695	Portal protein
FY140_13345	COG4235	cytochrome complex assembly
FY140_13350	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY140_13355	COG1138	Cytochrome C-type biogenesis protein
FY140_13360	COG3088	subunit of a heme lyase
FY140_13365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY140_13375	COG2205	protein histidine kinase activity
FY140_13380	COG3011	Protein conserved in bacteria
FY140_13395	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY140_13400	COG2202	Pas domain
FY140_13400	COG2205	protein histidine kinase activity
FY140_13410	COG0308	aminopeptidase N
FY140_13415	COG0697	spore germination
FY140_13430	COG0443	Heat shock 70 kDa protein
FY140_13485	COG0604	alcohol dehydrogenase
FY140_13490	COG1733	regulation of RNA biosynthetic process
FY140_13495	COG1968	undecaprenyl-diphosphatase activity
FY140_13500	COG2239	Acts as a magnesium transporter
FY140_13505	COG2814	Major facilitator Superfamily
FY140_13510	COG1597	lipid kinase activity
FY140_13535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY140_13560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY140_13745	COG0741	lytic transglycosylase activity
FY140_13750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_13755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY140_13760	COG0840	transmembrane signaling receptor activity
FY140_13770	COG1758	RNA polymerase activity
FY140_13790	COG0736	holo-[acyl-carrier-protein] synthase activity
FY140_13795	COG0681	Belongs to the peptidase S26 family
FY140_13800	COG0571	ribonuclease III activity
FY140_13805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY140_13815	COG0784	Response regulator, receiver
FY140_13820	COG1381	Involved in DNA repair and RecF pathway recombination
FY140_13830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY140_13840	COG1418	mRNA catabolic process
FY140_13850	COG0346	lactoylglutathione lyase activity
FY140_13870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_13875	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY140_13880	COG0668	transmembrane transport
FY140_13890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY140_13920	COG1742	UPF0060 membrane protein
FY140_13935	COG1183	phosphatidylcholine synthase activity
FY140_13940	COG0688	phosphatidylethanolamine metabolic process
FY140_13945	COG5265	(ABC) transporter
FY140_13985	COG2852	Protein conserved in bacteria
FY140_13990	COG0215	cysteine-tRNA ligase activity
FY140_13995	COG4221	oxidoreductase activity
FY140_14000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY140_14005	COG1286	toxin biosynthetic process
FY140_14025	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY140_14035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY140_14045	COG5265	(ABC) transporter
FY140_14050	COG0305	Participates in initiation and elongation during chromosome replication
FY140_14070	COG0359	binds to the 23S rRNA
FY140_14080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY140_14085	COG0360	Binds together with S18 to 16S ribosomal RNA
FY140_14090	COG0667	Aldo Keto reductase
FY140_14095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY140_14105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY140_14110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY140_14120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY140_14125	COG1561	YicC-like family, N-terminal region
FY140_14130	COG0194	GDP metabolic process
FY140_14150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY140_14155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY140_14165	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY140_14180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY140_14205	COG3300	MHYT domain
FY140_14205	COG5001	Diguanylate cyclase
FY140_14210	COG4191	Histidine kinase
FY140_14215	COG4566	intracellular signal transduction
FY140_14225	COG0488	(ABC) transporter
FY140_14230	COG3706	GGDEF domain
FY140_14240	COG0105	UTP biosynthetic process
FY140_14260	COG0314	molybdopterin synthase activity
FY140_14270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY140_14275	COG0322	excinuclease ABC activity
FY140_14280	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_14290	COG0625	glutathione transferase activity
FY140_14305	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY140_14310	COG0243	molybdopterin cofactor binding
FY140_14335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY140_14340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY140_14350	COG0628	permease
FY140_14360	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY140_14365	COG0248	Ppx GppA phosphatase
FY140_14390	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY140_14400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY140_14405	COG0477	Major facilitator Superfamily
FY140_14410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY140_14415	COG4452	Inner membrane protein CreD
FY140_14420	COG0840	transmembrane signaling receptor activity
FY140_14425	COG0659	secondary active sulfate transmembrane transporter activity
FY140_14435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY140_14445	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY140_14455	COG0113	porphobilinogen synthase activity
FY140_14475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY140_14480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY140_14485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY140_14485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY140_14495	COG1280	lysine exporter protein (LysE YggA)
FY140_14500	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY140_14505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY140_14510	COG2814	Major facilitator Superfamily
FY140_14515	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY140_14535	COG0416	fatty acid biosynthetic process
FY140_14540	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY140_14545	COG0776	regulation of translation
FY140_14575	COG0789	Transcriptional regulator
FY140_14580	COG0601	transmembrane transport
FY140_14585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_14590	COG0444	Belongs to the ABC transporter superfamily
FY140_14610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY140_14615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY140_14630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY140_14635	COG0583	DNA-binding transcription factor activity
FY140_14645	COG0737	Belongs to the 5'-nucleotidase family
FY140_14665	COG2897	thiosulfate sulfurtransferase activity
FY140_14680	COG0415	Belongs to the DNA photolyase family
FY140_14690	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY140_14720	COG3932	Exopolysaccharide synthesis, ExoD
FY140_14725	COG1238	metal cluster binding
FY140_14795	COG1612	heme a metabolic process
FY140_14805	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY140_14810	COG0010	Belongs to the arginase family
FY140_14815	COG1396	sequence-specific DNA binding
FY140_14825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY140_14830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY140_14840	COG1832	CoA-binding protein
FY140_14870	COG0740	serine-type endopeptidase activity
FY140_14875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY140_14880	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY140_14890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY140_14910	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY140_14915	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY140_14920	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY140_14930	COG0649	NAD binding
FY140_14940	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY140_14945	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY140_14955	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY140_14960	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY140_14970	COG0713	ATP synthesis coupled electron transport
FY140_14985	COG1007	ATP synthesis coupled electron transport
FY140_14990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY140_14990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY140_15005	COG0442	prolyl-tRNA aminoacylation
FY140_15015	COG1136	(ABC) transporter
FY140_15030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY140_15040	COG0784	Response regulator, receiver
FY140_15050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY140_15055	COG0477	Major facilitator Superfamily
FY140_15070	COG0557	exoribonuclease II activity
FY140_15075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY140_15085	COG0758	DNA mediated transformation
FY140_15090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY140_15100	COG0540	Belongs to the ATCase OTCase family
FY140_15110	COG1960	acyl-CoA dehydrogenase activity
FY140_15115	COG0456	acetyltransferase
FY140_15140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY140_15145	COG2824	Alkylphosphonate utilization operon protein PhnA
FY140_15150	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY140_15155	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY140_15160	COG0154	amidase activity
FY140_15165	COG3811	Belongs to the UPF0386 family
FY140_15180	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY140_15190	COG0456	acetyltransferase
FY140_15210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY140_15215	COG0439	Biotin carboxylase
FY140_15220	COG0511	ligase activity, forming carbon-carbon bonds
FY140_15225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY140_15235	COG0436	Aminotransferase
FY140_15255	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_15260	COG1530	ribonuclease E activity
FY140_15270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY140_15290	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY140_15295	COG0384	phenazine biosynthesis protein PhzF
FY140_15310	COG0633	Ferredoxin
FY140_15325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY140_15330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY140_15340	COG3768	UPF0283 membrane protein
FY140_15345	COG3106	COG3106 Predicted ATPase
FY140_15375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY140_15405	COG0537	adenosine 5'-monophosphoramidase activity
FY140_15430	COG0052	Belongs to the universal ribosomal protein uS2 family
FY140_15435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY140_15440	COG0528	UMP kinase activity
FY140_15445	COG0233	cytoplasmic translational termination
FY140_15450	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY140_15460	COG0750	zinc metalloprotease
FY140_15465	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY140_15470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY140_15475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY140_15480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY140_15485	COG3494	Protein of unknown function (DUF1009)
FY140_15490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY140_15495	COG2186	Transcriptional regulator
FY140_15505	COG0765	amino acid transport
FY140_15510	COG0765	amino acid transport
FY140_15520	COG0372	Belongs to the citrate synthase family
FY140_15535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY140_15545	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY140_15550	COG0148	phosphopyruvate hydratase activity
FY140_15560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY140_15565	COG0022	dehydrogenase e1 component
FY140_15565	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY140_15570	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY140_15580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY140_15590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY140_15595	COG0697	spore germination
FY140_15610	COG2867	negative regulation of translational initiation
FY140_15615	COG1546	Belongs to the CinA family
FY140_15620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY140_15620	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY140_15630	COG3852	Histidine kinase
FY140_15635	COG2204	response regulator
FY140_15640	COG5000	phosphorelay sensor kinase activity
FY140_15645	COG2204	response regulator
FY140_15650	COG0569	domain protein
FY140_15655	COG1923	regulation of RNA biosynthetic process
FY140_15660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY140_15665	COG3956	TIGRFAM MazG family protein
FY140_15675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY140_15675	COG1648	precorrin-2 dehydrogenase activity
FY140_15710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY140_15710	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY140_15715	COG0509	glycine decarboxylation via glycine cleavage system
FY140_15720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY140_15745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY140_15770	COG0251	oxidation-reduction process
FY140_15775	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY140_15785	COG1671	Belongs to the UPF0178 family
FY140_15800	COG0450	alkyl hydroperoxide reductase
FY140_15810	COG0625	glutathione transferase activity
FY140_15815	COG0456	acetyltransferase
FY140_15835	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY140_15850	COG0436	Aminotransferase
FY140_15870	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_15875	COG3836	Belongs to the HpcH HpaI aldolase family
FY140_15915	COG2801	Transposase and inactivated derivatives
FY140_15920	COG0431	NADPH-dependent FMN reductase
FY140_15935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY140_15940	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_15950	COG3321	synthase
FY140_15950	COG0604	alcohol dehydrogenase
FY140_15955	COG0604	alcohol dehydrogenase
FY140_15955	COG3321	synthase
FY140_15995	COG0321	lipoyl(octanoyl) transferase activity
FY140_15995	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY140_16000	COG0084	hydrolase, TatD family'
FY140_16005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY140_16015	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY140_16070	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY140_16075	COG2095	MarC family integral membrane protein
FY140_16080	COG0517	IMP dehydrogenase activity
FY140_16080	COG0617	tRNA 3'-terminal CCA addition
FY140_16080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY140_16085	COG0629	single-stranded DNA binding
FY140_16090	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY140_16100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY140_16120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY140_16125	COG1121	(ABC) transporter
FY140_16145	COG0667	Aldo Keto reductase
FY140_16155	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY140_16235	COG2239	Acts as a magnesium transporter
FY140_16240	COG0243	molybdopterin cofactor binding
FY140_16250	COG0242	peptide deformylase activity
FY140_16260	COG2202	Pas domain
FY140_16260	COG2205	protein histidine kinase activity
FY140_16270	COG0321	lipoyl(octanoyl) transferase activity
FY140_16275	COG1064	alcohol dehydrogenase
FY140_16305	COG1862	Preprotein translocase
FY140_16320	COG1309	transcriptional regulator
FY140_16325	COG2124	cytochrome p450
FY140_16340	COG0596	Alpha beta hydrolase
FY140_16350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY140_16355	COG0626	cystathionine gamma-synthase activity
FY140_16360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY140_16365	COG4597	amino acid ABC transporter
FY140_16370	COG0765	amino acid transport
FY140_16375	COG1126	abc transporter atp-binding protein
FY140_16390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY140_16405	COG0436	Aminotransferase
FY140_16435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY140_16440	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY140_16445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY140_16450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY140_16455	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY140_16475	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY140_16480	COG1489	DNA binding
FY140_16485	COG0024	Methionine aminopeptidase
FY140_16490	COG2003	Belongs to the UPF0758 family
FY140_16505	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY140_16520	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY140_16525	COG0546	phosphoglycolate phosphatase activity
FY140_16535	COG0114	fumarate hydratase activity
FY140_16540	COG0504	CTP synthase activity
FY140_16550	COG0149	triose-phosphate isomerase activity
FY140_16560	COG0187	DNA topoisomerase II activity
FY140_16570	COG0740	serine-type endopeptidase activity
FY140_16580	COG0640	Transcriptional regulator
FY140_16585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY140_16590	COG0745	RESPONSE REGULATOR receiver
FY140_16605	COG3264	Mechanosensitive ion channel
FY140_16605	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY140_16670	COG1127	ABC transporter
FY140_16675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY140_16680	COG4948	Mandelate Racemase Muconate Lactonizing
FY140_16690	COG0281	malic enzyme
FY140_16690	COG0280	phosphate acetyltransferase
FY140_16710	COG0778	Nitroreductase
FY140_16715	COG0823	Involved in the tonB-independent uptake of proteins
FY140_16730	COG1368	sulfuric ester hydrolase activity
FY140_16755	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY140_16780	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY140_16800	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY140_16815	COG0318	PFAM AMP-dependent synthetase and ligase
FY140_16825	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY140_16825	COG0512	Glutamine amidotransferase of anthranilate synthase
FY140_16830	COG0343	queuine tRNA-ribosyltransferase activity
FY140_16835	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY140_16850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY140_16870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY140_16875	COG0134	indole-3-glycerol-phosphate synthase activity
FY140_16880	COG0315	cyclic pyranopterin monophosphate synthase activity
FY140_16885	COG0303	'Molybdopterin
FY140_16890	COG3706	GGDEF domain
FY140_16900	COG0475	glutathione-regulated potassium exporter activity
FY140_16900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY140_16910	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY140_16915	COG0697	spore germination
FY140_16920	COG2814	Major facilitator Superfamily
FY140_16925	COG0746	molybdenum cofactor guanylyltransferase activity
FY140_16930	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY140_16935	COG0739	heme binding
FY140_16940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY140_16945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY140_16950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY140_16955	COG0805	protein transport
FY140_16960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY140_16965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY140_16970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY140_16975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY140_16980	COG1472	Belongs to the glycosyl hydrolase 3 family
FY140_16990	COG0018	arginyl-trna synthetase
FY140_16995	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY140_17020	COG0525	valine-tRNA ligase activity
FY140_17030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY140_17055	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY140_17060	COG1058	Belongs to the CinA family
FY140_17060	COG1546	Belongs to the CinA family
FY140_17065	COG0589	response to stress
FY140_17070	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY140_17075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY140_17145	COG0583	DNA-binding transcription factor activity
FY140_17150	COG1902	pentaerythritol trinitrate reductase activity
FY140_17155	COG0583	DNA-binding transcription factor activity
FY140_17160	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_17170	COG1335	isochorismatase
FY140_17175	COG0583	DNA-binding transcription factor activity
FY140_17180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY140_17250	COG1914	H( )-stimulated, divalent metal cation uptake system
FY140_17260	COG1132	(ABC) transporter
FY140_17265	COG0628	permease
FY140_17300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY140_17310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY140_17320	COG0302	gtp cyclohydrolase
FY140_17325	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY140_17330	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY140_17340	COG0516	GMP reductase activity
FY140_17340	COG0517	IMP dehydrogenase activity
FY140_17370	COG1760	l-serine dehydratase
FY140_17400	COG0583	DNA-binding transcription factor activity
FY140_17415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY140_17415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY140_17420	COG0347	Belongs to the P(II) protein family
FY140_17425	COG0174	glutamine synthetase
FY140_17455	COG0697	spore germination
FY140_17465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY140_17475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY140_17485	COG3668	Plasmid stabilization system
FY140_17490	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FY140_17505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY140_17510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY140_17515	COG2186	Transcriptional regulator
FY140_17525	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY140_17530	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY140_17535	COG3845	ABC transporter
FY140_17540	COG1183	phosphatidylcholine synthase activity
FY140_17545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY140_17550	COG0679	Auxin Efflux Carrier
FY140_17555	COG0785	Cytochrome C biogenesis protein
FY140_17575	COG1278	Cold shock
FY140_17680	COG0577	efflux transmembrane transporter activity
FY140_17680	COG1136	(ABC) transporter
FY140_17685	COG0577	efflux transmembrane transporter activity
FY140_17685	COG1136	(ABC) transporter
FY140_17710	COG2151	metal-sulfur cluster biosynthetic enzyme
FY140_17715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY140_17720	COG0719	Fe-S assembly protein
FY140_17725	COG0396	ATPase activity
FY140_17730	COG0719	Fe-S assembly protein
FY140_17735	COG1104	cysteine desulfurase activity
FY140_17740	COG2945	thiolester hydrolase activity
FY140_17745	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY140_17750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY140_17760	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY140_17765	COG2833	Protein of unknown function (DUF455)
FY140_17770	COG0739	heme binding
FY140_17775	COG0513	Belongs to the DEAD box helicase family
FY140_17800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY140_17810	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY140_17815	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY140_17820	COG0047	phosphoribosylformylglycinamidine synthase activity
FY140_17835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY140_17840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY140_17860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY140_17865	COG2814	Major facilitator Superfamily
FY140_17870	COG0483	inositol monophosphate 1-phosphatase activity
FY140_17875	COG0483	inositol monophosphate 1-phosphatase activity
FY140_17880	COG0037	tRNA processing
FY140_17885	COG2066	Belongs to the glutaminase family
FY140_17890	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY140_17895	COG0861	Integral membrane protein TerC family
FY140_17910	COG1280	lysine exporter protein (LysE YggA)
FY140_17915	COG3093	addiction module antidote protein HigA
FY140_17930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY140_17935	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY140_17945	COG0538	isocitrate dehydrogenase activity
FY140_17970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY140_17975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY140_17980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_17985	COG2313	pseudouridylate synthase activity
FY140_17995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY140_18000	COG4215	(ABC) transporter
FY140_18010	COG5425	PFAM Usg family protein
FY140_18025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY140_18030	COG1522	sequence-specific DNA binding
FY140_18035	COG1573	uracil-dna glycosylase
FY140_18045	COG2202	Pas domain
FY140_18045	COG2205	protein histidine kinase activity
FY140_18055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY140_18060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY140_18080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY140_18085	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_18090	COG1129	ABC transporter
FY140_18100	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY140_18105	COG3959	Transketolase, thiamine diphosphate binding domain
FY140_18110	COG3958	Transketolase
FY140_18115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY140_18120	COG2390	Transcriptional regulator
FY140_18130	COG0842	Transport permease protein
FY140_18135	COG1131	(ABC) transporter
FY140_18140	COG0730	response to heat
FY140_18140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY140_18160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY140_18165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY140_18185	COG0129	dihydroxy-acid dehydratase activity
FY140_18190	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY140_18195	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY140_18205	COG0203	ribosomal protein L17
FY140_18210	COG0202	RNA polymerase activity
FY140_18215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY140_18220	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY140_18225	COG0563	adenylate kinase activity
FY140_18230	COG0201	protein transport
FY140_18235	COG0200	Binds to the 23S rRNA
FY140_18240	COG1841	ribosomal large subunit assembly
FY140_18245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY140_18250	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY140_18255	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY140_18260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY140_18265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY140_18270	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY140_18275	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY140_18280	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY140_18285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY140_18290	COG0255	Belongs to the universal ribosomal protein uL29 family
FY140_18295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY140_18300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY140_18305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY140_18310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY140_18315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY140_18320	COG0089	rRNA binding
FY140_18325	COG0088	Forms part of the polypeptide exit tunnel
FY140_18330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY140_18335	COG0051	transcription antitermination factor activity, RNA binding
FY140_18340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY140_18345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY140_18350	COG0049	tRNA binding
FY140_18355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY140_18375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY140_18380	COG0085	RNA polymerase activity
FY140_18385	COG0222	ribosome binding
FY140_18390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY140_18395	COG0081	regulation of translation
FY140_18400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY140_18410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY140_18425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY140_18430	COG0861	Integral membrane protein TerC family
FY140_18435	COG3895	Periplasmic Protein
FY140_18465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY140_18470	COG1607	acyl-coa hydrolase
FY140_18495	COG2910	NAD(P)H-binding
FY140_18500	COG1733	regulation of RNA biosynthetic process
FY140_18515	COG0556	nucleotide-excision repair
FY140_18525	COG2382	esterase
FY140_18545	COG0484	heat shock protein binding
FY140_18575	COG3842	ATPase activity
FY140_18580	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY140_18585	COG1840	ABC-type Fe3 transport system, periplasmic component
FY140_18590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY140_18605	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY140_18615	COG1733	regulation of RNA biosynthetic process
FY140_18625	COG2207	Transcriptional regulator
FY140_18630	COG1064	alcohol dehydrogenase
FY140_18635	COG1252	NADH dehydrogenase
FY140_18640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY140_18645	COG2197	response regulator
FY140_18650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY140_18655	COG0702	epimerase
FY140_18695	COG0656	L-ascorbic acid biosynthetic process
FY140_18710	COG0440	acetolactate synthase activity
FY140_18715	COG0028	Belongs to the TPP enzyme family
FY140_18725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY140_18730	COG3830	Belongs to the UPF0237 family
FY140_18730	COG0560	Phosphoserine phosphatase
FY140_18740	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_18750	COG0330	HflC and HflK could
FY140_18755	COG0330	HflC and HflK could
FY140_18765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY140_18805	COG0277	FAD linked oxidase domain protein
FY140_18810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY140_18855	COG1335	isochorismatase
FY140_18880	COG2264	protein methyltransferase activity
FY140_18885	COG1999	signal sequence binding
FY140_18895	COG0835	chemotaxis
FY140_18905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY140_18910	COG0583	DNA-binding transcription factor activity
FY140_18920	COG1247	-acetyltransferase
FY140_18930	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY140_18935	COG0497	DNA recombination
FY140_18940	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY140_18950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY140_18955	COG0849	cell division
FY140_18960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY140_18965	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY140_18970	COG0477	Major facilitator Superfamily
FY140_18975	COG3300	MHYT domain
FY140_18975	COG5001	Diguanylate cyclase
FY140_18980	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY140_18985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY140_18990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY140_19000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY140_19005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY140_19015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY140_19030	COG0275	rRNA processing
FY140_19035	COG2001	Belongs to the MraZ family
FY140_19070	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY140_19075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FY140_19100	COG4106	trans-aconitate 2-methyltransferase activity
FY140_19120	COG2226	methyltransferase
FY140_19130	COG2267	carboxylic ester hydrolase activity
FY140_19135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY140_19165	COG1376	ErfK ybiS ycfS ynhG family protein
FY140_19170	COG2814	Major facilitator Superfamily
FY140_19200	COG0174	glutamine synthetase
FY140_19205	COG0531	amino acid
FY140_19215	COG1737	Transcriptional regulator
FY140_19220	COG2182	Extracellular solute-binding protein
FY140_19235	COG3842	ATPase activity
FY140_19295	COG2968	Membrane
FY140_19305	COG0432	Pfam Uncharacterised protein family UPF0047
FY140_19320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY140_19325	COG0358	DNA primase activity
FY140_19335	COG0505	Belongs to the CarA family
FY140_19340	COG0534	Mate efflux family protein
FY140_19355	COG2321	neutral zinc metallopeptidase
FY140_19370	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY140_19380	COG3706	GGDEF domain
FY140_19395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY140_19405	COG1522	sequence-specific DNA binding
FY140_19410	COG0492	ferredoxin-NADP+ reductase activity
FY140_19415	COG0583	DNA-binding transcription factor activity
FY140_19425	COG1902	pentaerythritol trinitrate reductase activity
FY140_19450	COG0387	Pfam Sodium calcium exchanger
FY140_19455	COG0436	Aminotransferase
FY140_19460	COG2199	diguanylate cyclase activity
FY140_19460	COG2200	EAL domain
FY140_19475	COG1278	Cold shock
FY140_19480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY140_19490	COG1846	Transcriptional regulator
FY140_19495	COG0745	RESPONSE REGULATOR receiver
FY140_19500	COG2205	protein histidine kinase activity
FY140_19505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY140_19525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY140_19535	COG1496	oxidoreductase activity
FY140_19540	COG0006	proline dipeptidase activity
FY140_19550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY140_19570	COG0463	Glycosyl transferase, family 2
FY140_19575	COG0840	transmembrane signaling receptor activity
FY140_19580	COG1012	belongs to the aldehyde dehydrogenase family
FY140_19585	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY140_19590	COG3300	MHYT domain
FY140_19590	COG5001	Diguanylate cyclase
FY140_19595	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY140_19600	COG5001	Diguanylate cyclase
FY140_19610	COG0193	aminoacyl-tRNA hydrolase activity
FY140_19620	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY140_19640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY140_19650	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY140_19650	COG2857	Cytochrome c1
FY140_19670	COG1132	(ABC) transporter
FY140_19680	COG1132	(ABC) transporter
FY140_19685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FY140_19690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY140_19705	COG0408	coproporphyrinogen oxidase activity
FY140_19720	COG0617	tRNA 3'-terminal CCA addition
FY140_19735	COG0714	Associated with various cellular activities
FY140_19755	COG0454	-acetyltransferase
FY140_19770	COG0477	Major facilitator Superfamily
FY140_19780	COG0435	Glutathione S-transferase
FY140_19785	COG0494	nUDIX hydrolase
FY140_19795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY140_19810	COG3135	benzoate transporter
FY140_19820	COG4944	Protein of unknown function (DUF1109)
FY140_19835	COG0740	serine-type endopeptidase activity
FY140_19850	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY140_19855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY140_19880	COG4175	Glycine betaine
FY140_19895	COG1435	thymidine kinase activity
FY140_19915	COG2862	Uncharacterized protein family, UPF0114
FY140_19920	COG1629	transport
FY140_19920	COG4771	TonB-dependent receptor
FY140_19930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY140_19930	COG0512	Glutamine amidotransferase of anthranilate synthase
FY140_19945	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY140_19960	COG0366	Alpha amylase catalytic
FY140_19965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_19985	COG1160	GTP binding
FY140_20005	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY140_20015	COG0024	Methionine aminopeptidase
FY140_20025	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_20035	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY140_20045	COG0583	DNA-binding transcription factor activity
FY140_20060	COG0402	S-adenosylhomocysteine deaminase activity
FY140_20080	COG1309	transcriptional regulator
FY140_20085	COG1686	Belongs to the peptidase S11 family
FY140_20095	COG2351	hydroxyisourate hydrolase activity
FY140_20100	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY140_20135	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY140_20145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_20145	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY140_20150	COG0784	Response regulator, receiver
FY140_20150	COG2205	protein histidine kinase activity
FY140_20150	COG5002	protein histidine kinase activity
FY140_20155	COG0513	Belongs to the DEAD box helicase family
FY140_20165	COG2259	Doxx family
FY140_20170	COG1376	ErfK ybiS ycfS ynhG family protein
FY140_20180	COG2308	Evidence 4 Homologs of previously reported genes of
FY140_20190	COG1305	Transglutaminase-like
FY140_20215	COG4214	carbohydrate transport
FY140_20225	COG4213	ABC transporter substrate-binding protein
FY140_20255	COG0840	transmembrane signaling receptor activity
FY140_20270	COG0646	methionine synthase
FY140_20270	COG1410	methionine synthase
FY140_20315	COG1215	transferase activity, transferring glycosyl groups
FY140_20345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY140_20350	COG2346	COG2346, Truncated hemoglobins
FY140_20370	COG1309	transcriptional regulator
FY140_20385	COG0494	nUDIX hydrolase
FY140_20395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_20400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_20425	COG1234	tRNA 3'-trailer cleavage
FY140_20430	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY140_20435	COG0830	nickel cation binding
FY140_20440	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY140_20455	COG0804	urea catabolic process
FY140_20460	COG1442	glycosyl transferase family 8
FY140_20465	COG3755	Protein conserved in bacteria
FY140_20475	COG0832	Belongs to the urease beta subunit family
FY140_20480	COG3813	Protein conserved in bacteria
FY140_20485	COG0831	urea catabolic process
FY140_20490	COG0829	nickel cation binding
FY140_20515	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY140_20530	COG0174	glutamine synthetase
FY140_20535	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_20540	COG0784	Response regulator, receiver
FY140_20540	COG2198	Histidine kinase
FY140_20540	COG5002	protein histidine kinase activity
FY140_20585	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY140_20660	COG0564	pseudouridine synthase activity
FY140_20670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY140_20680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY140_20710	COG0346	lactoylglutathione lyase activity
FY140_20720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY140_20730	COG2832	Protein of unknown function (DUF454)
FY140_20735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY140_20740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_20745	COG4558	Periplasmic binding protein
FY140_20755	COG3721	Heme iron utilization protein
FY140_20770	COG2205	protein histidine kinase activity
FY140_20815	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY140_20820	COG4605	iron ion homeostasis
FY140_20825	COG4604	ABC transporter, ATP-binding protein
FY140_20830	COG0783	Belongs to the Dps family
FY140_20845	COG0656	L-ascorbic acid biosynthetic process
FY140_20850	COG2814	Major facilitator Superfamily
FY140_20860	COG0583	DNA-binding transcription factor activity
FY140_20865	COG0657	acetylesterase activity
FY140_20870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_20890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY140_20895	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY140_20900	COG0288	reversible hydration of carbon dioxide
FY140_20910	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY140_20925	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY140_20930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY140_20935	COG0778	Nitroreductase
FY140_20940	COG2267	carboxylic ester hydrolase activity
FY140_20945	COG0251	oxidation-reduction process
FY140_20950	COG1335	isochorismatase
FY140_20955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY140_20965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY140_20980	COG1175	transmembrane transport
FY140_20985	COG0395	ABC-type sugar transport system, permease component
FY140_20990	COG3842	ATPase activity
FY140_20995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_21020	COG4608	Belongs to the ABC transporter superfamily
FY140_21025	COG0444	Belongs to the ABC transporter superfamily
FY140_21030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_21035	COG0601	transmembrane transport
FY140_21040	COG4166	transmembrane transport
FY140_21090	COG2159	amidohydrolase
FY140_21095	COG1960	acyl-CoA dehydrogenase activity
FY140_21125	COG0745	RESPONSE REGULATOR receiver
FY140_21135	COG1902	pentaerythritol trinitrate reductase activity
FY140_21135	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY140_21140	COG3842	ATPase activity
FY140_21150	COG1840	ABC-type Fe3 transport system, periplasmic component
FY140_21155	COG1840	ABC-type Fe3 transport system, periplasmic component
FY140_21160	COG0745	RESPONSE REGULATOR receiver
FY140_21170	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY140_21175	COG0583	DNA-binding transcription factor activity
FY140_21210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY140_21220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_21225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY140_21235	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY140_21240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY140_21245	COG1509	lysine 2,3-aminomutase activity
FY140_21260	COG0583	DNA-binding transcription factor activity
FY140_21265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_21270	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY140_21275	COG4149	molybdate abc transporter
FY140_21280	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY140_21295	COG2022	thiamine diphosphate biosynthetic process
FY140_21310	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY140_21315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY140_21325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY140_21345	COG1132	(ABC) transporter
FY140_21350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY140_21395	COG4166	transmembrane transport
FY140_21405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY140_21415	COG0438	transferase activity, transferring glycosyl groups
FY140_21420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY140_21425	COG3142	Participates in the control of copper homeostasis
FY140_21445	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_21450	COG1737	Transcriptional regulator
FY140_21460	COG3842	ATPase activity
FY140_21470	COG0395	ABC-type sugar transport system, permease component
FY140_21490	COG2188	Transcriptional regulator
FY140_21495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY140_21500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY140_21505	COG1940	carbohydrate kinase activity
FY140_21515	COG0671	phosphoesterase, PA-phosphatase related
FY140_21520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY140_21530	COG0156	8-amino-7-oxononanoate synthase activity
FY140_21540	COG0729	surface antigen
FY140_21550	COG0835	chemotaxis
FY140_21560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY140_21565	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY140_21570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY140_21575	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY140_21580	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY140_21585	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY140_21600	COG4974	Belongs to the 'phage' integrase family
FY140_21625	COG1280	lysine exporter protein (LysE YggA)
FY140_21635	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY140_21640	COG0567	Dehydrogenase, E1 component
FY140_21645	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY140_21650	COG0045	succinate-CoA ligase (ADP-forming) activity
FY140_21655	COG0039	L-malate dehydrogenase activity
FY140_21660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY140_21695	COG2264	protein methyltransferase activity
FY140_21710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY140_21715	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY140_21720	COG0181	hydroxymethylbilane synthase activity
FY140_21760	COG1872	DUF167
FY140_21765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY140_21775	COG1217	gtp-binding protein TYPA
FY140_21780	COG0339	signal peptide processing
FY140_21790	COG1846	Transcriptional regulator
FY140_21800	COG0137	argininosuccinate synthase activity
FY140_21810	COG1280	lysine exporter protein (LysE YggA)
FY140_21815	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY140_21820	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY140_21830	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY140_21845	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY140_21850	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY140_21855	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY140_21865	COG4181	ATPase activity
FY140_21875	COG0670	Belongs to the BI1 family
FY140_21890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY140_21895	COG4133	protoheme IX ABC transporter activity
FY140_21900	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY140_21905	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY140_21930	COG2917	probably involved in intracellular septation
FY140_21935	COG0552	protein localization to endoplasmic reticulum
FY140_21940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY140_21945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY140_21955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY140_21960	COG0287	Prephenate dehydrogenase
FY140_21960	COG1605	Chorismate mutase
FY140_21965	COG0228	four-way junction DNA binding
FY140_21970	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY140_21975	COG0336	Belongs to the RNA methyltransferase TrmD family
FY140_21985	COG0335	large ribosomal subunit rRNA binding
FY140_21995	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY140_22000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_22015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY140_22035	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY140_22055	COG0488	(ABC) transporter
FY140_22065	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY140_22075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY140_22080	COG0142	geranyltranstransferase activity
FY140_22085	COG2885	chlorophyll binding
FY140_22090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY140_22095	COG2223	nitrite transmembrane transporter activity
FY140_22100	COG1349	DNA-binding transcription factor activity
FY140_22105	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY140_22110	COG2197	response regulator
FY140_22115	COG1132	(ABC) transporter
FY140_22125	COG3459	Glycosyltransferase 36 associated
FY140_22130	COG1473	amidohydrolase
FY140_22135	COG0579	oxidoreductase
FY140_22145	COG0129	dihydroxy-acid dehydratase activity
FY140_22150	COG2084	Dehydrogenase
FY140_22155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY140_22160	COG0277	FAD linked oxidase domain protein
FY140_22165	COG2186	Transcriptional regulator
FY140_22175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY140_22180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY140_22185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY140_22190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY140_22200	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY140_22205	COG0495	leucyl-tRNA aminoacylation
FY140_22220	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY140_22225	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY140_22235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY140_22240	COG1946	Acyl-CoA thioesterase
FY140_22245	COG0347	Belongs to the P(II) protein family
FY140_22250	COG0004	ammonium transporteR
FY140_22255	COG1674	ftsk spoiiie
FY140_22260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY140_22275	COG0745	RESPONSE REGULATOR receiver
FY140_22285	COG1329	Transcriptional regulator
FY140_22290	COG2902	Dehydrogenase
FY140_22295	COG2270	Major facilitator Superfamily
FY140_22310	COG1028	Short-chain dehydrogenase reductase Sdr
FY140_22325	COG0494	nUDIX hydrolase
FY140_22330	COG2861	carbohydrate metabolic process
FY140_22335	COG0793	Belongs to the peptidase S41A family
FY140_22345	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY140_22350	COG0799	negative regulation of ribosome biogenesis
FY140_22355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY140_22360	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY140_22365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY140_22370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY140_22385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY140_22390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY140_22415	COG0066	3-isopropylmalate dehydratase activity
FY140_22420	COG0473	3-isopropylmalate dehydrogenase activity
FY140_22425	COG1858	cytochrome C peroxidase
FY140_22430	COG1797	cobyrinic acid a,c-diamide synthase activity
FY140_22440	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY140_22505	COG1492	cobalamin metabolic process
FY140_22510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FY140_22520	COG4948	Mandelate Racemase Muconate Lactonizing
FY140_22525	COG3254	rhamnose metabolic process
FY140_22530	COG0246	Mannitol dehydrogenase
FY140_22535	COG1063	alcohol dehydrogenase
FY140_22555	COG4214	carbohydrate transport
FY140_22560	COG1129	ABC transporter
FY140_22565	COG2186	Transcriptional regulator
FY140_22570	COG2721	sulfolactate sulfo-lyase activity
FY140_22575	COG0138	bifunctional purine biosynthesis protein purh
FY140_22585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY140_22585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY140_22590	COG0501	Belongs to the peptidase M48B family
FY140_22610	COG0357	Ribosomal RNA small subunit methyltransferase G
FY140_22615	COG0445	tRNA wobble uridine modification
FY140_22620	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY140_22625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY140_22630	COG1981	membrane
FY140_22635	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY140_22640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY140_22645	COG0424	maF-like protein
FY140_22650	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY140_22655	COG0237	dephospho-CoA kinase activity
FY140_22665	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY140_22670	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY140_22680	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY140_22705	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY140_22720	COG0135	phosphoribosylanthranilate isomerase activity
FY140_22725	COG0133	tryptophan synthase activity
FY140_22730	COG0159	tryptophan synthase activity
FY140_22735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY140_22740	COG0285	dihydrofolate synthase activity
FY140_22750	COG1074	ATP-dependent DNA helicase activity
FY140_22760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY140_22770	COG2205	protein histidine kinase activity
FY140_22775	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY140_22780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY140_22785	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY140_22785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY140_22790	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY140_22795	COG0642	Histidine kinase
FY140_22800	COG0745	RESPONSE REGULATOR receiver
FY140_22805	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY140_22815	COG1652	LysM domain
FY140_22820	COG1072	(Pantothenic acid kinase))
FY140_22825	COG0140	phosphoribosyl-ATP diphosphatase activity
FY140_22830	COG0107	imidazoleglycerol-phosphate synthase activity
FY140_22835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY140_22840	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY140_22850	COG0131	Imidazoleglycerol-phosphate dehydratase
FY140_22855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY140_22860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY140_22870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY140_22885	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY140_22895	COG1643	Atp-dependent helicase
FY140_22955	COG1072	(Pantothenic acid kinase))
FY140_22965	COG1780	Probably involved in ribonucleotide reductase function
FY140_22985	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY140_23010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY140_23020	COG2813	Specifically methylates the guanine in position
FY140_23025	COG1185	polyribonucleotide nucleotidyltransferase activity
FY140_23030	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY140_23035	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY140_23040	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY140_23045	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY140_23045	COG3064	Membrane
FY140_23060	COG0779	Required for maturation of 30S ribosomal subunits
FY140_23065	COG2814	Major facilitator Superfamily
FY140_23070	COG2951	lytic endotransglycosylase activity
FY140_23075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY140_23085	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY140_23090	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY140_23105	COG2816	NAD+ diphosphatase activity
FY140_23110	COG0077	Prephenate dehydratase
FY140_23110	COG1605	Chorismate mutase
FY140_23115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY140_23120	COG3474	cytochrome
FY140_23130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY140_23135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY140_23140	COG1278	Cold shock
FY140_23145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY140_23155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY140_23155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY140_23165	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY140_23195	COG2900	Belongs to the SlyX family
FY140_23205	COG0484	heat shock protein binding
FY140_23210	COG0443	Heat shock 70 kDa protein
FY140_23225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY140_23230	COG1744	ABC transporter substrate-binding protein PnrA-like
FY140_23235	COG3845	ABC transporter
FY140_23240	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY140_23245	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY140_23250	COG0295	cytidine deaminase activity
FY140_23255	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY140_23260	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY140_23265	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY140_23275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY140_23280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY140_23285	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY140_23295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY140_23300	COG1845	cytochrome c oxidase, subunit III
FY140_23305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY140_23315	COG0477	Major facilitator Superfamily
FY140_23320	COG0070	glutamate synthase
FY140_23320	COG0069	glutamate synthase activity
FY140_23320	COG0067	glutamate synthase
FY140_23325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY140_23340	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY140_23350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY140_23380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY140_23400	COG0848	biopolymer transport protein
FY140_23410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY140_23425	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY140_23430	COG3454	Phosphonate metabolism
FY140_23435	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY140_23440	COG3639	organic phosphonate transmembrane transporter activity
FY140_23445	COG3639	organic phosphonate transmembrane transporter activity
FY140_23450	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FY140_23455	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY140_23465	COG4778	phosphonate C-P lyase system protein PhnL
FY140_23470	COG4107	phosphonate C-P lyase system protein PhnK
FY140_23475	COG3627	carbon phosphorus lyase activity
FY140_23480	COG3626	phosphonate metabolism
FY140_23485	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY140_23490	COG3624	Phosphonate C-P lyase system protein PhnG
FY140_23495	COG2188	Transcriptional regulator
FY140_23500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY140_23505	COG0837	glucose binding
FY140_23510	COG1803	Methylglyoxal synthase
FY140_23515	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY140_23520	COG4166	transmembrane transport
FY140_23525	COG4174	ABC transporter (Permease)
FY140_23530	COG4239	(ABC) transporter, permease
FY140_23535	COG4172	Belongs to the ABC transporter superfamily
FY140_23540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_23545	COG0174	glutamine synthetase
FY140_23550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY140_23555	COG3265	gluconokinase activity
FY140_23560	COG1174	glycine betaine transport
FY140_23565	COG1125	glycine betaine transport
FY140_23570	COG1174	glycine betaine transport
FY140_23575	COG1732	Glycine betaine
FY140_23585	COG1959	2 iron, 2 sulfur cluster binding
FY140_23590	COG1840	ABC-type Fe3 transport system, periplasmic component
FY140_23600	COG4269	membrane
FY140_23615	COG0697	spore germination
FY140_23630	COG0791	NLP P60 protein
FY140_23640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY140_23645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY140_23680	COG4964	Belongs to the GSP D family
FY140_23725	COG3422	double-strand break repair
FY140_23730	COG3757	hydrolase, family 25
FY140_23735	COG0697	spore germination
FY140_23740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY140_23765	COG0481	GTPase activity
FY140_23770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY140_23785	COG1396	sequence-specific DNA binding
FY140_23800	COG1917	Cupin 2, conserved barrel domain protein
FY140_23800	COG2169	Transcriptional regulator
FY140_23805	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY140_23830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY140_23835	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY140_23840	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY140_23850	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY140_23855	COG0072	phenylalanine-tRNA ligase activity
FY140_23855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY140_23860	COG0667	Aldo Keto reductase
FY140_23880	COG4977	sequence-specific DNA binding
FY140_23905	COG1570	exodeoxyribonuclease VII activity
FY140_23910	COG4948	Mandelate Racemase Muconate Lactonizing
FY140_23920	COG1846	Transcriptional regulator
FY140_23925	COG0697	spore germination
FY140_23930	COG2309	aminopeptidase activity
FY140_23940	COG1393	Belongs to the ArsC family
FY140_23955	COG1309	transcriptional regulator
FY140_23965	COG0519	Catalyzes the synthesis of GMP from XMP
FY140_23965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY140_23980	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY140_24010	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY140_24020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY140_24030	COG1968	undecaprenyl-diphosphatase activity
FY140_24045	COG0284	orotidine-5'-phosphate decarboxylase activity
FY140_24055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY140_24065	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY140_24070	COG0792	nuclease activity
FY140_24085	COG1175	transmembrane transport
FY140_24095	COG3842	ATPase activity
FY140_24105	COG0189	ligase activity
FY140_24110	COG0606	chelatase, subunit chli
FY140_24115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY140_24120	COG1280	lysine exporter protein (LysE YggA)
FY140_24125	COG0756	dUTP diphosphatase activity
FY140_24130	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY140_24135	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY140_24150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY140_24155	COG2226	methyltransferase
FY140_24160	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY140_24165	COG1024	Enoyl-CoA hydratase
FY140_24170	COG0268	Binds directly to 16S ribosomal RNA
FY140_24180	COG1475	DNA binding
FY140_24185	COG0640	Transcriptional regulator
FY140_24200	COG0640	Transcriptional regulator
FY140_24225	COG0431	NADPH-dependent FMN reductase
FY140_24270	COG3177	Filamentation induced by cAMP protein fic
FY140_24280	COG1278	Cold shock
FY140_24340	COG0840	transmembrane signaling receptor activity
FY140_24350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY140_24365	COG1175	transmembrane transport
FY140_24375	COG3842	ATPase activity
FY140_24385	COG2390	Transcriptional regulator
FY140_24430	COG0583	DNA-binding transcription factor activity
FY140_24440	COG1609	Transcriptional regulator
FY140_24470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY140_24490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY140_24535	COG3177	Filamentation induced by cAMP protein fic
FY140_24540	COG1566	PFAM secretion protein HlyD family protein
FY140_24555	COG2207	Transcriptional regulator
FY140_24565	COG2080	2 iron, 2 sulfur cluster binding
FY140_24570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FY140_24575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FY140_24580	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FY140_24590	COG0071	Belongs to the small heat shock protein (HSP20) family
FY140_24615	COG1280	lysine exporter protein (LysE YggA)
FY140_24630	COG2197	response regulator
FY140_24635	COG4585	Histidine kinase
FY140_24645	COG5001	Diguanylate cyclase
FY140_24645	COG3300	MHYT domain
FY140_24700	COG4191	Histidine kinase
FY140_24720	COG0028	Belongs to the TPP enzyme family
FY140_24735	COG1309	transcriptional regulator
FY140_24740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY140_24745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY140_24755	COG2814	Major facilitator Superfamily
FY140_24800	COG3451	type IV secretory pathway VirB4
FY140_24815	COG4962	Type ii secretion system protein e