locus-tag	class	description
FY141_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY141_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY141_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY141_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY141_00025	COG1420	regulation of RNA biosynthetic process
FY141_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY141_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY141_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY141_00050	COG1137	ATPase activity
FY141_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY141_00065	COG0616	signal peptide processing
FY141_00070	COG0776	regulation of translation
FY141_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY141_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY141_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY141_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY141_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY141_00115	COG0728	peptidoglycan biosynthetic process
FY141_00125	COG0180	Tryptophanyl-tRNA synthetase
FY141_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY141_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY141_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY141_00165	COG1702	phosphate starvation-inducible protein PhoH
FY141_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY141_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY141_00185	COG1396	sequence-specific DNA binding
FY141_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY141_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY141_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_00210	COG0242	peptide deformylase activity
FY141_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY141_00220	COG0101	tRNA pseudouridine synthase activity
FY141_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY141_00235	COG2171	N-acyltransferase activity
FY141_00245	COG0840	transmembrane signaling receptor activity
FY141_00250	COG1957	nucleoside hydrolase
FY141_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY141_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY141_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY141_00295	COG0706	membrane insertase activity
FY141_00300	COG0594	ribonuclease P activity
FY141_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY141_00310	COG0840	transmembrane signaling receptor activity
FY141_00325	COG2226	methyltransferase
FY141_00330	COG3842	ATPase activity
FY141_00335	COG1175	transmembrane transport
FY141_00340	COG0395	ABC-type sugar transport system, permease component
FY141_00355	COG0427	acetyl-CoA hydrolase
FY141_00365	COG3938	Belongs to the proline racemase family
FY141_00370	COG0418	dihydroorotase activity
FY141_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY141_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY141_00400	COG0166	Belongs to the GPI family
FY141_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY141_00410	COG3842	ATPase activity
FY141_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY141_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY141_00425	COG4774	siderophore transport
FY141_00470	COG2326	polyphosphate kinase activity
FY141_00475	COG5002	protein histidine kinase activity
FY141_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY141_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY141_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY141_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY141_00505	COG0745	RESPONSE REGULATOR receiver
FY141_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY141_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY141_00530	COG2967	ApaG domain
FY141_00545	COG0717	Belongs to the dCTP deaminase family
FY141_00605	COG3561	AntA/AntB antirepressor
FY141_00645	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY141_00700	COG5484	DNA packaging
FY141_00700	COG3728	DNA packaging
FY141_00825	COG0582	viral genome integration into host DNA
FY141_00850	COG0419	ATPase involved in DNA repair
FY141_00870	COG1396	sequence-specific DNA binding
FY141_00910	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY141_00915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY141_00965	COG0167	dihydroorotate dehydrogenase activity
FY141_01000	COG1959	2 iron, 2 sulfur cluster binding
FY141_01005	COG1201	RNA secondary structure unwinding
FY141_01035	COG1960	acyl-CoA dehydrogenase activity
FY141_01040	COG0183	Belongs to the thiolase family
FY141_01045	COG1024	Enoyl-CoA hydratase
FY141_01045	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY141_01070	COG1320	monovalent cation:proton antiporter activity
FY141_01075	COG2212	antiporter activity
FY141_01080	COG1863	multisubunit Na H antiporter MnhE subunit
FY141_01085	COG0651	ATP synthesis coupled electron transport
FY141_01090	COG1006	Multisubunit Na H antiporter MnhC subunit
FY141_01095	COG2111	Na H antiporter
FY141_01095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY141_01105	COG0840	transmembrane signaling receptor activity
FY141_01115	COG0745	RESPONSE REGULATOR receiver
FY141_01120	COG0643	Histidine kinase
FY141_01120	COG2198	Histidine kinase
FY141_01125	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY141_01130	COG2201	protein-glutamate methylesterase activity
FY141_01135	COG0745	RESPONSE REGULATOR receiver
FY141_01140	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY141_01150	COG1766	The M ring may be actively involved in energy transduction
FY141_01155	COG2771	luxR family
FY141_01165	COG0840	transmembrane signaling receptor activity
FY141_01165	COG2972	Histidine kinase
FY141_01170	COG2198	Histidine kinase
FY141_01170	COG2205	protein histidine kinase activity
FY141_01170	COG0784	Response regulator, receiver
FY141_01175	COG1970	mechanosensitive ion channel activity
FY141_01180	COG0436	Aminotransferase
FY141_01195	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY141_01200	COG0424	maF-like protein
FY141_01205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY141_01215	COG5328	Belongs to the UPF0262 family
FY141_01220	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY141_01230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY141_01250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY141_01260	COG1338	Plays a role in the flagellum-specific transport system
FY141_01270	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY141_01280	COG1706	bacterial-type flagellum-dependent cell motility
FY141_01285	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY141_01290	COG4786	Flagellar basal body rod
FY141_01295	COG1677	Flagellar hook-basal body complex protein FliE
FY141_01300	COG1558	bacterial-type flagellum-dependent cell motility
FY141_01305	COG1815	bacterial-type flagellum-dependent cell motility
FY141_01315	COG1157	protein secretion by the type III secretion system
FY141_01320	COG4786	Flagellar basal body rod
FY141_01330	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY141_01335	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY141_01340	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY141_01345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY141_01350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY141_01370	COG1360	Flagellar Motor Protein
FY141_01415	COG5443	negative regulation of bacterial-type flagellum assembly
FY141_01420	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY141_01430	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY141_01470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY141_01475	COG1609	Transcriptional regulator
FY141_01480	COG1653	transport
FY141_01485	COG1175	transmembrane transport
FY141_01490	COG0395	ABC-type sugar transport system, permease component
FY141_01495	COG0366	Alpha amylase catalytic
FY141_01500	COG3842	ATPase activity
FY141_01515	COG0129	dihydroxy-acid dehydratase activity
FY141_01520	COG0363	glucosamine-6-phosphate deaminase activity
FY141_01525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY141_01530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_01540	COG2081	HI0933 family
FY141_01560	COG2224	Isocitrate lyase
FY141_01575	COG3842	ATPase activity
FY141_01580	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_01585	COG1177	transmembrane transport
FY141_01600	COG2205	protein histidine kinase activity
FY141_01610	COG0248	Ppx GppA phosphatase
FY141_01615	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY141_01620	COG0477	Major facilitator Superfamily
FY141_01650	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY141_01655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY141_01665	COG0142	geranyltranstransferase activity
FY141_01690	COG0752	glycyl-tRNA synthetase alpha subunit
FY141_01700	COG1704	LemA family
FY141_01705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY141_01715	COG0751	glycine-tRNA ligase activity
FY141_01720	COG1683	Conserved Protein
FY141_01725	COG0840	transmembrane signaling receptor activity
FY141_01735	COG0151	Belongs to the GarS family
FY141_01740	COG2183	response to ionizing radiation
FY141_01745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY141_01770	COG0583	DNA-binding transcription factor activity
FY141_01790	COG0306	phosphate transporter
FY141_01800	COG0561	phosphatase activity
FY141_01805	COG0438	transferase activity, transferring glycosyl groups
FY141_01810	COG2186	Transcriptional regulator
FY141_01820	COG0583	DNA-binding transcription factor activity
FY141_01825	COG0277	FAD linked oxidase domain protein
FY141_01830	COG0277	FAD linked oxidase domain protein
FY141_01835	COG0247	lactate metabolic process
FY141_01845	COG1376	ErfK ybiS ycfS ynhG family protein
FY141_01850	COG2818	Glycosylase
FY141_01860	COG2855	membrane
FY141_01865	COG0583	DNA-binding transcription factor activity
FY141_01895	COG0124	histidyl-tRNA synthetase
FY141_01905	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY141_01910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY141_01915	COG2259	Doxx family
FY141_01925	COG0459	protein refolding
FY141_01930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY141_01940	COG0196	riboflavin kinase activity
FY141_01945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY141_01955	COG0590	tRNA wobble adenosine to inosine editing
FY141_01960	COG1187	pseudouridine synthase activity
FY141_01965	COG0742	ribosomal rna small subunit methyltransferase
FY141_01970	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY141_01980	COG0312	modulator of DNA gyrase
FY141_01985	COG0483	inositol monophosphate 1-phosphatase activity
FY141_01995	COG1519	Transferase
FY141_02005	COG1663	tetraacyldisaccharide 4'-kinase activity
FY141_02015	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY141_02020	COG0745	RESPONSE REGULATOR receiver
FY141_02025	COG3300	MHYT domain
FY141_02025	COG5001	Diguanylate cyclase
FY141_02030	COG3386	PFAM SMP-30 Gluconolaconase
FY141_02035	COG0800	Aldolase
FY141_02040	COG3734	2-keto-3-deoxy-galactonokinase
FY141_02045	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_02050	COG1414	Transcriptional regulator
FY141_02055	COG2197	response regulator
FY141_02070	COG0598	Magnesium transport protein CorA
FY141_02075	COG3158	transport of potassium into the cell
FY141_02090	COG0356	it plays a direct role in the translocation of protons across the membrane
FY141_02100	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY141_02105	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY141_02120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY141_02140	COG0009	L-threonylcarbamoyladenylate synthase
FY141_02150	COG4638	Rieske (2fe-2S)
FY141_02175	COG1960	acyl-CoA dehydrogenase activity
FY141_02190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY141_02195	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY141_02200	COG0840	transmembrane signaling receptor activity
FY141_02210	COG1522	sequence-specific DNA binding
FY141_02235	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY141_02240	COG1741	Belongs to the pirin family
FY141_02245	COG1722	exodeoxyribonuclease VII activity
FY141_02250	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY141_02255	COG1268	BioY protein
FY141_02260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY141_02265	COG1122	ATPase activity
FY141_02270	COG3214	Protein conserved in bacteria
FY141_02275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY141_02275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY141_02280	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY141_02300	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY141_02315	COG0259	pyridoxamine-phosphate oxidase activity
FY141_02345	COG0312	modulator of DNA gyrase
FY141_02360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY141_02365	COG0109	protoheme IX farnesyltransferase activity
FY141_02370	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY141_02385	COG3346	SURF1 family
FY141_02390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY141_02395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY141_02400	COG0328	RNA-DNA hybrid ribonuclease activity
FY141_02410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY141_02410	COG0678	peroxiredoxin activity
FY141_02420	COG1678	Uncharacterized ACR, COG1678
FY141_02425	COG3237	CsbD-like
FY141_02435	COG3300	MHYT domain
FY141_02435	COG5001	Diguanylate cyclase
FY141_02440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY141_02445	COG0612	Peptidase, M16
FY141_02470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY141_02475	COG1802	Transcriptional regulator
FY141_02490	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY141_02495	COG3609	addiction module antidote protein, CC2985 family
FY141_02500	COG3668	Plasmid stabilization system
FY141_02510	COG1194	a g-specific adenine glycosylase
FY141_02525	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY141_02530	COG1196	nuclear chromosome segregation
FY141_02535	COG2514	catechol 2,3-dioxygenase activity
FY141_02540	COG0574	Belongs to the PEP-utilizing enzyme family
FY141_02540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY141_02550	COG1823	symporter activity
FY141_02575	COG0579	oxidoreductase
FY141_02590	COG2895	sulfate adenylyltransferase (ATP) activity
FY141_02595	COG0175	sulfate reduction
FY141_02600	COG0175	sulfate reduction
FY141_02605	COG1959	2 iron, 2 sulfur cluster binding
FY141_02610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY141_02615	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY141_02620	COG4208	sulfate ABC transporter
FY141_02625	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY141_02635	COG2200	EAL domain
FY141_02635	COG2203	Gaf domain
FY141_02635	COG2199	diguanylate cyclase activity
FY141_02645	COG1309	transcriptional regulator
FY141_02650	COG1012	belongs to the aldehyde dehydrogenase family
FY141_02655	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY141_02685	COG0625	glutathione transferase activity
FY141_02695	COG0477	Major facilitator Superfamily
FY141_02705	COG3657	addiction module killer protein
FY141_02715	COG1793	dna ligase
FY141_02735	COG1376	ErfK ybiS ycfS ynhG family protein
FY141_02740	COG1376	ErfK ybiS ycfS ynhG family protein
FY141_02745	COG1846	Transcriptional regulator
FY141_02750	COG1764	response to oxidative stress
FY141_02765	COG0488	(ABC) transporter
FY141_02800	COG4221	oxidoreductase activity
FY141_02815	COG0433	COG0433 Predicted ATPase
FY141_02825	COG1733	regulation of RNA biosynthetic process
FY141_02830	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY141_02845	COG0656	L-ascorbic acid biosynthetic process
FY141_02850	COG3781	membrane
FY141_02855	COG2378	regulation of single-species biofilm formation
FY141_02865	COG4106	trans-aconitate 2-methyltransferase activity
FY141_02870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY141_02875	COG0840	transmembrane signaling receptor activity
FY141_02880	COG0583	DNA-binding transcription factor activity
FY141_02895	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY141_02915	COG3909	cytochrome
FY141_02920	COG2010	Cytochrome c
FY141_02955	COG0789	Transcriptional regulator
FY141_02980	COG4175	Glycine betaine
FY141_02980	COG0517	IMP dehydrogenase activity
FY141_02985	COG4176	ABC-type proline glycine betaine transport system permease component
FY141_03005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_03015	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY141_03015	COG2169	Transcriptional regulator
FY141_03025	COG2514	catechol 2,3-dioxygenase activity
FY141_03045	COG1272	protein, Hemolysin III
FY141_03055	COG1280	lysine exporter protein (LysE YggA)
FY141_03060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY141_03065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY141_03065	COG2111	Na H antiporter
FY141_03070	COG2111	Na H antiporter
FY141_03075	COG1006	Multisubunit Na H antiporter MnhC subunit
FY141_03080	COG0651	ATP synthesis coupled electron transport
FY141_03085	COG1863	multisubunit Na H antiporter MnhE subunit
FY141_03090	COG2212	antiporter activity
FY141_03095	COG1320	monovalent cation:proton antiporter activity
FY141_03100	COG4957	zinc ion binding
FY141_03115	COG2166	iron-sulfur cluster assembly
FY141_03125	COG2205	protein histidine kinase activity
FY141_03170	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY141_03175	COG2983	Belongs to the UPF0260 family
FY141_03190	COG2217	Heavy metal translocating P-type atpase
FY141_03220	COG2814	Major facilitator Superfamily
FY141_03225	COG1621	beta-fructofuranosidase activity
FY141_03230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY141_03280	COG4695	Portal protein
FY141_03385	COG4235	cytochrome complex assembly
FY141_03390	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY141_03395	COG1138	Cytochrome C-type biogenesis protein
FY141_03400	COG3088	subunit of a heme lyase
FY141_03405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY141_03410	COG0745	RESPONSE REGULATOR receiver
FY141_03415	COG2205	protein histidine kinase activity
FY141_03420	COG3011	Protein conserved in bacteria
FY141_03425	COG3713	MltA-interacting MipA family protein
FY141_03430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY141_03435	COG2202	Pas domain
FY141_03435	COG2205	protein histidine kinase activity
FY141_03445	COG0308	aminopeptidase N
FY141_03450	COG0697	spore germination
FY141_03465	COG0443	Heat shock 70 kDa protein
FY141_03500	COG0604	alcohol dehydrogenase
FY141_03505	COG1733	regulation of RNA biosynthetic process
FY141_03510	COG1968	undecaprenyl-diphosphatase activity
FY141_03515	COG2239	Acts as a magnesium transporter
FY141_03520	COG2814	Major facilitator Superfamily
FY141_03545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY141_03570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY141_03610	COG0741	lytic transglycosylase activity
FY141_03615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_03620	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY141_03625	COG0840	transmembrane signaling receptor activity
FY141_03635	COG1758	RNA polymerase activity
FY141_03655	COG0736	holo-[acyl-carrier-protein] synthase activity
FY141_03660	COG0681	Belongs to the peptidase S26 family
FY141_03665	COG0571	ribonuclease III activity
FY141_03670	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY141_03680	COG0784	Response regulator, receiver
FY141_03685	COG1381	Involved in DNA repair and RecF pathway recombination
FY141_03695	COG2226	methyltransferase
FY141_03705	COG1418	mRNA catabolic process
FY141_03715	COG0346	lactoylglutathione lyase activity
FY141_03730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_03735	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY141_03740	COG0668	transmembrane transport
FY141_03750	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY141_03780	COG1742	UPF0060 membrane protein
FY141_03795	COG1183	phosphatidylcholine synthase activity
FY141_03800	COG0688	phosphatidylethanolamine metabolic process
FY141_03805	COG5265	(ABC) transporter
FY141_03845	COG2852	Protein conserved in bacteria
FY141_03850	COG0215	cysteine-tRNA ligase activity
FY141_03855	COG4221	oxidoreductase activity
FY141_03860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY141_03865	COG1286	toxin biosynthetic process
FY141_03880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY141_03890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY141_03900	COG0305	Participates in initiation and elongation during chromosome replication
FY141_03920	COG0359	binds to the 23S rRNA
FY141_03930	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY141_03935	COG0360	Binds together with S18 to 16S ribosomal RNA
FY141_03945	COG0667	Aldo Keto reductase
FY141_03950	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY141_03960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY141_03965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY141_03975	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY141_03980	COG1561	YicC-like family, N-terminal region
FY141_03985	COG0194	GDP metabolic process
FY141_04000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY141_04005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY141_04015	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY141_04030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY141_04050	COG3706	GGDEF domain
FY141_04050	COG4251	negative regulation of phosphorylation
FY141_04050	COG5001	Diguanylate cyclase
FY141_04050	COG2203	Gaf domain
FY141_04055	COG3300	MHYT domain
FY141_04055	COG5001	Diguanylate cyclase
FY141_04060	COG4191	Histidine kinase
FY141_04065	COG4566	intracellular signal transduction
FY141_04075	COG0488	(ABC) transporter
FY141_04080	COG3706	GGDEF domain
FY141_04090	COG0105	UTP biosynthetic process
FY141_04110	COG0314	molybdopterin synthase activity
FY141_04120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY141_04125	COG0322	excinuclease ABC activity
FY141_04130	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_04155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY141_04160	COG0243	molybdopterin cofactor binding
FY141_04175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY141_04180	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY141_04185	COG2226	methyltransferase
FY141_04190	COG0628	permease
FY141_04200	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY141_04205	COG0248	Ppx GppA phosphatase
FY141_04230	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY141_04240	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY141_04245	COG0477	Major facilitator Superfamily
FY141_04250	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY141_04260	COG0840	transmembrane signaling receptor activity
FY141_04265	COG0659	secondary active sulfate transmembrane transporter activity
FY141_04275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY141_04280	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY141_04290	COG0113	porphobilinogen synthase activity
FY141_04310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY141_04315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY141_04320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY141_04320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY141_04330	COG1280	lysine exporter protein (LysE YggA)
FY141_04335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY141_04340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY141_04345	COG2814	Major facilitator Superfamily
FY141_04350	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY141_04370	COG0416	fatty acid biosynthetic process
FY141_04375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY141_04380	COG0776	regulation of translation
FY141_04415	COG0601	transmembrane transport
FY141_04420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_04425	COG0444	Belongs to the ABC transporter superfamily
FY141_04435	COG0747	negative chemotaxis
FY141_04445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY141_04450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY141_04465	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY141_04470	COG0583	DNA-binding transcription factor activity
FY141_04475	COG0737	Belongs to the 5'-nucleotidase family
FY141_04495	COG2897	thiosulfate sulfurtransferase activity
FY141_04510	COG0415	Belongs to the DNA photolyase family
FY141_04520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY141_04550	COG3932	Exopolysaccharide synthesis, ExoD
FY141_04555	COG1238	metal cluster binding
FY141_04630	COG1612	heme a metabolic process
FY141_04640	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY141_04645	COG0010	Belongs to the arginase family
FY141_04650	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY141_04655	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY141_04665	COG1832	CoA-binding protein
FY141_04695	COG2124	cytochrome p450
FY141_04700	COG2199	diguanylate cyclase activity
FY141_04705	COG0740	serine-type endopeptidase activity
FY141_04710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY141_04715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY141_04725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY141_04750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY141_04755	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY141_04760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY141_04770	COG0649	NAD binding
FY141_04780	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY141_04785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY141_04795	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY141_04800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY141_04810	COG0713	ATP synthesis coupled electron transport
FY141_04825	COG1007	ATP synthesis coupled electron transport
FY141_04830	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY141_04830	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY141_04845	COG0442	prolyl-tRNA aminoacylation
FY141_04855	COG1136	(ABC) transporter
FY141_04870	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY141_04890	COG0784	Response regulator, receiver
FY141_04900	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY141_04905	COG0477	Major facilitator Superfamily
FY141_04920	COG0557	exoribonuclease II activity
FY141_04925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY141_04935	COG0758	DNA mediated transformation
FY141_04940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY141_04950	COG0540	Belongs to the ATCase OTCase family
FY141_04965	COG1960	acyl-CoA dehydrogenase activity
FY141_04970	COG0456	acetyltransferase
FY141_04990	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY141_04995	COG2824	Alkylphosphonate utilization operon protein PhnA
FY141_05000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY141_05005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY141_05010	COG0154	amidase activity
FY141_05015	COG0456	acetyltransferase
FY141_05020	COG3811	Belongs to the UPF0386 family
FY141_05035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY141_05065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY141_05070	COG0439	Biotin carboxylase
FY141_05075	COG0511	ligase activity, forming carbon-carbon bonds
FY141_05080	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY141_05090	COG0436	Aminotransferase
FY141_05110	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_05115	COG1530	ribonuclease E activity
FY141_05125	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY141_05145	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY141_05150	COG0384	phenazine biosynthesis protein PhzF
FY141_05170	COG0633	Ferredoxin
FY141_05185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY141_05190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY141_05200	COG3768	UPF0283 membrane protein
FY141_05205	COG3106	COG3106 Predicted ATPase
FY141_05235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY141_05270	COG0537	adenosine 5'-monophosphoramidase activity
FY141_05295	COG0052	Belongs to the universal ribosomal protein uS2 family
FY141_05300	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY141_05305	COG0528	UMP kinase activity
FY141_05310	COG0233	cytoplasmic translational termination
FY141_05315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY141_05325	COG0750	zinc metalloprotease
FY141_05330	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY141_05335	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY141_05340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY141_05345	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY141_05350	COG3494	Protein of unknown function (DUF1009)
FY141_05355	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY141_05360	COG2186	Transcriptional regulator
FY141_05370	COG0765	amino acid transport
FY141_05375	COG0765	amino acid transport
FY141_05385	COG0372	Belongs to the citrate synthase family
FY141_05400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY141_05425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY141_05430	COG1459	type II secretion system
FY141_05485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY141_05490	COG0148	phosphopyruvate hydratase activity
FY141_05500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY141_05505	COG0022	dehydrogenase e1 component
FY141_05505	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY141_05510	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY141_05520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY141_05530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY141_05535	COG0697	spore germination
FY141_05550	COG2867	negative regulation of translational initiation
FY141_05555	COG1546	Belongs to the CinA family
FY141_05560	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY141_05560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY141_05570	COG3852	Histidine kinase
FY141_05575	COG2204	response regulator
FY141_05580	COG5000	phosphorelay sensor kinase activity
FY141_05585	COG2204	response regulator
FY141_05590	COG0569	domain protein
FY141_05595	COG1923	regulation of RNA biosynthetic process
FY141_05600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY141_05605	COG3956	TIGRFAM MazG family protein
FY141_05615	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY141_05615	COG1648	precorrin-2 dehydrogenase activity
FY141_05655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY141_05655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY141_05660	COG0509	glycine decarboxylation via glycine cleavage system
FY141_05665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY141_05690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY141_05695	COG0564	pseudouridine synthase activity
FY141_05715	COG0251	oxidation-reduction process
FY141_05720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY141_05730	COG1671	Belongs to the UPF0178 family
FY141_05745	COG0450	alkyl hydroperoxide reductase
FY141_05750	COG0625	glutathione transferase activity
FY141_05760	COG2801	Transposase and inactivated derivatives
FY141_05765	COG0431	NADPH-dependent FMN reductase
FY141_05775	COG0798	PFAM Bile acid sodium symporter
FY141_05780	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY141_05795	COG0321	lipoyl(octanoyl) transferase activity
FY141_05795	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY141_05800	COG0084	hydrolase, TatD family'
FY141_05805	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY141_05815	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY141_05865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY141_05870	COG2095	MarC family integral membrane protein
FY141_05875	COG0517	IMP dehydrogenase activity
FY141_05875	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY141_05875	COG0617	tRNA 3'-terminal CCA addition
FY141_05885	COG0629	single-stranded DNA binding
FY141_05890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY141_05900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY141_05920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY141_05925	COG1121	(ABC) transporter
FY141_05945	COG0667	Aldo Keto reductase
FY141_05955	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY141_06040	COG2239	Acts as a magnesium transporter
FY141_06045	COG0243	molybdopterin cofactor binding
FY141_06055	COG0242	peptide deformylase activity
FY141_06065	COG2205	protein histidine kinase activity
FY141_06065	COG2202	Pas domain
FY141_06075	COG0321	lipoyl(octanoyl) transferase activity
FY141_06080	COG1064	alcohol dehydrogenase
FY141_06110	COG1862	Preprotein translocase
FY141_06130	COG2124	cytochrome p450
FY141_06145	COG0596	Alpha beta hydrolase
FY141_06155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY141_06160	COG0626	cystathionine gamma-synthase activity
FY141_06165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_06170	COG4597	amino acid ABC transporter
FY141_06175	COG0765	amino acid transport
FY141_06180	COG1126	abc transporter atp-binding protein
FY141_06195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY141_06210	COG0436	Aminotransferase
FY141_06240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY141_06250	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY141_06255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY141_06260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY141_06275	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY141_06280	COG1489	DNA binding
FY141_06285	COG0024	Methionine aminopeptidase
FY141_06290	COG2003	Belongs to the UPF0758 family
FY141_06305	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY141_06330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY141_06335	COG0546	phosphoglycolate phosphatase activity
FY141_06345	COG0114	fumarate hydratase activity
FY141_06355	COG0504	CTP synthase activity
FY141_06365	COG0149	triose-phosphate isomerase activity
FY141_06375	COG0187	DNA topoisomerase II activity
FY141_06385	COG0740	serine-type endopeptidase activity
FY141_06395	COG0640	Transcriptional regulator
FY141_06400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY141_06405	COG0745	RESPONSE REGULATOR receiver
FY141_06420	COG3264	Mechanosensitive ion channel
FY141_06420	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY141_06485	COG1127	ABC transporter
FY141_06490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY141_06495	COG4948	Mandelate Racemase Muconate Lactonizing
FY141_06505	COG0281	malic enzyme
FY141_06505	COG0280	phosphate acetyltransferase
FY141_06515	COG0778	Nitroreductase
FY141_06520	COG0823	Involved in the tonB-independent uptake of proteins
FY141_06535	COG1368	sulfuric ester hydrolase activity
FY141_06560	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY141_06580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY141_06600	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY141_06615	COG0318	PFAM AMP-dependent synthetase and ligase
FY141_06625	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY141_06625	COG0512	Glutamine amidotransferase of anthranilate synthase
FY141_06630	COG0343	queuine tRNA-ribosyltransferase activity
FY141_06635	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY141_06650	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY141_06665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY141_06670	COG0134	indole-3-glycerol-phosphate synthase activity
FY141_06675	COG0315	cyclic pyranopterin monophosphate synthase activity
FY141_06680	COG0303	'Molybdopterin
FY141_06685	COG3706	GGDEF domain
FY141_06695	COG0475	glutathione-regulated potassium exporter activity
FY141_06695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY141_06705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY141_06715	COG2814	Major facilitator Superfamily
FY141_06720	COG0746	molybdenum cofactor guanylyltransferase activity
FY141_06725	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY141_06730	COG0739	heme binding
FY141_06735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY141_06740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY141_06745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY141_06750	COG0805	protein transport
FY141_06755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY141_06760	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY141_06765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY141_06770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY141_06775	COG1472	Belongs to the glycosyl hydrolase 3 family
FY141_06785	COG0018	arginyl-trna synthetase
FY141_06790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY141_06815	COG0525	valine-tRNA ligase activity
FY141_06825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY141_06965	COG1525	nuclease
FY141_07040	COG3567	Phage-associated protein, HI1409 family
FY141_07090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY141_07280	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY141_07285	COG1546	Belongs to the CinA family
FY141_07285	COG1058	Belongs to the CinA family
FY141_07290	COG0589	response to stress
FY141_07295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY141_07305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY141_07315	COG0640	Transcriptional regulator
FY141_07320	COG1914	H( )-stimulated, divalent metal cation uptake system
FY141_07330	COG1132	(ABC) transporter
FY141_07335	COG0628	permease
FY141_07370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY141_07380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY141_07390	COG0302	gtp cyclohydrolase
FY141_07395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY141_07400	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY141_07410	COG0516	GMP reductase activity
FY141_07410	COG0517	IMP dehydrogenase activity
FY141_07445	COG1760	l-serine dehydratase
FY141_07485	COG0583	DNA-binding transcription factor activity
FY141_07500	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY141_07500	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY141_07510	COG0347	Belongs to the P(II) protein family
FY141_07515	COG0174	glutamine synthetase
FY141_07545	COG0697	spore germination
FY141_07555	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY141_07565	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY141_07595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY141_07605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY141_07610	COG2186	Transcriptional regulator
FY141_07620	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY141_07625	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY141_07630	COG3845	ABC transporter
FY141_07635	COG1183	phosphatidylcholine synthase activity
FY141_07640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY141_07645	COG0679	Auxin Efflux Carrier
FY141_07650	COG0785	Cytochrome C biogenesis protein
FY141_07670	COG1278	Cold shock
FY141_07720	COG0577	efflux transmembrane transporter activity
FY141_07720	COG1136	(ABC) transporter
FY141_07725	COG1136	(ABC) transporter
FY141_07725	COG0577	efflux transmembrane transporter activity
FY141_07750	COG2151	metal-sulfur cluster biosynthetic enzyme
FY141_07755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY141_07760	COG0719	Fe-S assembly protein
FY141_07765	COG0396	ATPase activity
FY141_07770	COG0719	Fe-S assembly protein
FY141_07775	COG1104	cysteine desulfurase activity
FY141_07780	COG2945	thiolester hydrolase activity
FY141_07785	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY141_07790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY141_07800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY141_07805	COG2833	Protein of unknown function (DUF455)
FY141_07810	COG0739	heme binding
FY141_07815	COG0513	Belongs to the DEAD box helicase family
FY141_07840	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY141_07850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY141_07855	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY141_07860	COG0047	phosphoribosylformylglycinamidine synthase activity
FY141_07875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY141_07880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY141_07900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY141_07905	COG2814	Major facilitator Superfamily
FY141_07910	COG0483	inositol monophosphate 1-phosphatase activity
FY141_07915	COG0483	inositol monophosphate 1-phosphatase activity
FY141_07920	COG0037	tRNA processing
FY141_07925	COG2066	Belongs to the glutaminase family
FY141_07930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY141_07935	COG0861	Integral membrane protein TerC family
FY141_07950	COG1280	lysine exporter protein (LysE YggA)
FY141_07960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY141_07965	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY141_07975	COG0538	isocitrate dehydrogenase activity
FY141_07985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY141_07990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY141_07995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_08000	COG2313	pseudouridylate synthase activity
FY141_08010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_08015	COG4215	(ABC) transporter
FY141_08025	COG5425	PFAM Usg family protein
FY141_08035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY141_08040	COG1522	sequence-specific DNA binding
FY141_08045	COG1573	uracil-dna glycosylase
FY141_08055	COG2202	Pas domain
FY141_08055	COG2205	protein histidine kinase activity
FY141_08060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY141_08065	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY141_08070	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY141_08085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY141_08090	COG0842	Transport permease protein
FY141_08095	COG1131	(ABC) transporter
FY141_08100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY141_08100	COG0730	response to heat
FY141_08120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY141_08125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY141_08145	COG0129	dihydroxy-acid dehydratase activity
FY141_08150	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY141_08155	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY141_08165	COG3739	integral membrane protein
FY141_08170	COG0203	ribosomal protein L17
FY141_08175	COG0202	RNA polymerase activity
FY141_08180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY141_08185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY141_08190	COG0563	adenylate kinase activity
FY141_08195	COG0201	protein transport
FY141_08200	COG0200	Binds to the 23S rRNA
FY141_08205	COG1841	ribosomal large subunit assembly
FY141_08210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY141_08215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY141_08220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY141_08225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY141_08230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY141_08235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY141_08240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY141_08245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY141_08250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY141_08255	COG0255	Belongs to the universal ribosomal protein uL29 family
FY141_08260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY141_08265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY141_08270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY141_08275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY141_08280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY141_08285	COG0089	rRNA binding
FY141_08290	COG0088	Forms part of the polypeptide exit tunnel
FY141_08295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY141_08300	COG0051	transcription antitermination factor activity, RNA binding
FY141_08305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY141_08310	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY141_08315	COG0049	tRNA binding
FY141_08320	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY141_08340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY141_08345	COG0085	RNA polymerase activity
FY141_08350	COG0222	ribosome binding
FY141_08355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY141_08360	COG0081	regulation of translation
FY141_08365	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY141_08375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY141_08385	COG1086	Polysaccharide biosynthesis protein
FY141_08390	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY141_08395	COG0861	Integral membrane protein TerC family
FY141_08400	COG3895	Periplasmic Protein
FY141_08420	COG1132	(ABC) transporter
FY141_08425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY141_08445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY141_08480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_08480	COG0784	Response regulator, receiver
FY141_08480	COG2205	protein histidine kinase activity
FY141_08480	COG2198	Histidine kinase
FY141_08485	COG0784	Response regulator, receiver
FY141_08490	COG2202	Pas domain
FY141_08490	COG3920	Histidine kinase
FY141_08495	COG0784	Response regulator, receiver
FY141_08500	COG4251	negative regulation of phosphorylation
FY141_08515	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY141_08520	COG1607	acyl-coa hydrolase
FY141_08540	COG2910	NAD(P)H-binding
FY141_08545	COG1733	regulation of RNA biosynthetic process
FY141_08560	COG0556	nucleotide-excision repair
FY141_08570	COG2382	esterase
FY141_08590	COG0484	heat shock protein binding
FY141_08610	COG3706	GGDEF domain
FY141_08630	COG1840	ABC-type Fe3 transport system, periplasmic component
FY141_08635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY141_08650	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY141_08660	COG2207	Transcriptional regulator
FY141_08665	COG1064	alcohol dehydrogenase
FY141_08670	COG1252	NADH dehydrogenase
FY141_08675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY141_08680	COG2197	response regulator
FY141_08685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY141_08720	COG0656	L-ascorbic acid biosynthetic process
FY141_08735	COG0440	acetolactate synthase activity
FY141_08740	COG0028	Belongs to the TPP enzyme family
FY141_08750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY141_08755	COG3830	Belongs to the UPF0237 family
FY141_08755	COG0560	Phosphoserine phosphatase
FY141_08775	COG0330	HflC and HflK could
FY141_08780	COG0330	HflC and HflK could
FY141_08790	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY141_08825	COG0277	FAD linked oxidase domain protein
FY141_08830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY141_08870	COG1335	isochorismatase
FY141_08895	COG2264	protein methyltransferase activity
FY141_08900	COG1999	signal sequence binding
FY141_08910	COG0835	chemotaxis
FY141_08920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY141_08925	COG0583	DNA-binding transcription factor activity
FY141_08935	COG1247	-acetyltransferase
FY141_08945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY141_08950	COG0497	DNA recombination
FY141_08955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY141_08965	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY141_08970	COG0849	cell division
FY141_08975	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY141_08980	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY141_08985	COG0477	Major facilitator Superfamily
FY141_08990	COG5001	Diguanylate cyclase
FY141_08995	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY141_09000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY141_09005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY141_09015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY141_09020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY141_09030	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY141_09045	COG0275	rRNA processing
FY141_09050	COG2001	Belongs to the MraZ family
FY141_09075	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY141_09105	COG4106	trans-aconitate 2-methyltransferase activity
FY141_09125	COG2226	methyltransferase
FY141_09135	COG2267	carboxylic ester hydrolase activity
FY141_09140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY141_09155	COG0251	oxidation-reduction process
FY141_09170	COG1376	ErfK ybiS ycfS ynhG family protein
FY141_09175	COG2814	Major facilitator Superfamily
FY141_09205	COG1012	belongs to the aldehyde dehydrogenase family
FY141_09210	COG0174	glutamine synthetase
FY141_09215	COG0531	amino acid
FY141_09225	COG1737	Transcriptional regulator
FY141_09230	COG2182	Extracellular solute-binding protein
FY141_09245	COG3842	ATPase activity
FY141_09305	COG2968	Membrane
FY141_09315	COG0432	Pfam Uncharacterised protein family UPF0047
FY141_09330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY141_09335	COG0358	DNA primase activity
FY141_09355	COG0505	Belongs to the CarA family
FY141_09360	COG0534	Mate efflux family protein
FY141_09375	COG2321	neutral zinc metallopeptidase
FY141_09390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY141_09400	COG3706	GGDEF domain
FY141_09415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY141_09425	COG1522	sequence-specific DNA binding
FY141_09430	COG0492	ferredoxin-NADP+ reductase activity
FY141_09435	COG0583	DNA-binding transcription factor activity
FY141_09445	COG1902	pentaerythritol trinitrate reductase activity
FY141_09470	COG0387	Pfam Sodium calcium exchanger
FY141_09475	COG0436	Aminotransferase
FY141_09480	COG2200	EAL domain
FY141_09480	COG2199	diguanylate cyclase activity
FY141_09495	COG1278	Cold shock
FY141_09500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY141_09510	COG1846	Transcriptional regulator
FY141_09515	COG0745	RESPONSE REGULATOR receiver
FY141_09525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY141_09545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY141_09555	COG1496	oxidoreductase activity
FY141_09570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY141_09580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY141_09595	COG0840	transmembrane signaling receptor activity
FY141_09600	COG1012	belongs to the aldehyde dehydrogenase family
FY141_09605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY141_09610	COG3300	MHYT domain
FY141_09610	COG5001	Diguanylate cyclase
FY141_09615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY141_09620	COG5001	Diguanylate cyclase
FY141_09630	COG0193	aminoacyl-tRNA hydrolase activity
FY141_09640	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY141_09665	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY141_09675	COG2857	Cytochrome c1
FY141_09675	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY141_09695	COG1132	(ABC) transporter
FY141_09705	COG1132	(ABC) transporter
FY141_09715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY141_09730	COG0408	coproporphyrinogen oxidase activity
FY141_09745	COG0617	tRNA 3'-terminal CCA addition
FY141_09760	COG0714	Associated with various cellular activities
FY141_09780	COG0454	-acetyltransferase
FY141_09795	COG0477	Major facilitator Superfamily
FY141_09805	COG0435	Glutathione S-transferase
FY141_09810	COG0494	nUDIX hydrolase
FY141_09820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY141_09825	COG3135	benzoate transporter
FY141_09850	COG0740	serine-type endopeptidase activity
FY141_09865	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY141_09870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY141_09895	COG4175	Glycine betaine
FY141_09915	COG1435	thymidine kinase activity
FY141_09940	COG1629	transport
FY141_09940	COG4771	TonB-dependent receptor
FY141_09950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY141_09950	COG0512	Glutamine amidotransferase of anthranilate synthase
FY141_09965	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY141_09975	COG0366	Alpha amylase catalytic
FY141_09980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_10000	COG1160	GTP binding
FY141_10020	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY141_10030	COG0024	Methionine aminopeptidase
FY141_10040	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_10060	COG0583	DNA-binding transcription factor activity
FY141_10075	COG0402	S-adenosylhomocysteine deaminase activity
FY141_10085	COG1304	FMN binding
FY141_10095	COG1309	transcriptional regulator
FY141_10100	COG1686	Belongs to the peptidase S11 family
FY141_10110	COG2351	hydroxyisourate hydrolase activity
FY141_10115	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY141_10140	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY141_10150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY141_10150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_10160	COG0513	Belongs to the DEAD box helicase family
FY141_10170	COG2259	Doxx family
FY141_10175	COG1376	ErfK ybiS ycfS ynhG family protein
FY141_10185	COG2308	Evidence 4 Homologs of previously reported genes of
FY141_10195	COG1305	Transglutaminase-like
FY141_10220	COG4214	carbohydrate transport
FY141_10230	COG4213	ABC transporter substrate-binding protein
FY141_10285	COG2948	multi-organism process
FY141_10295	COG3701	Conjugal transfer protein
FY141_10300	COG3846	protein secretion by the type IV secretion system
FY141_10315	COG3451	type IV secretory pathway VirB4
FY141_10330	COG4962	Type ii secretion system protein e
FY141_10355	COG0583	DNA-binding transcription factor activity
FY141_10365	COG1566	PFAM secretion protein HlyD family protein
FY141_10380	COG2207	Transcriptional regulator
FY141_10385	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_10395	COG0583	DNA-binding transcription factor activity
FY141_10405	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY141_10420	COG0583	DNA-binding transcription factor activity
FY141_10430	COG0741	lytic transglycosylase activity
FY141_10455	COG1192	Involved in chromosome partitioning
FY141_10490	COG2814	Major facilitator Superfamily
FY141_10500	COG5489	Protein of unknown function (DUF736)
FY141_10515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY141_10545	COG1204	response to ionizing radiation
FY141_10560	COG0514	ATP-dependent DNA helicase (RecQ)
FY141_10610	COG0583	DNA-binding transcription factor activity
FY141_10615	COG1902	pentaerythritol trinitrate reductase activity
FY141_10620	COG0583	DNA-binding transcription factor activity
FY141_10635	COG1335	isochorismatase
FY141_10640	COG0583	DNA-binding transcription factor activity
FY141_10645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY141_10655	COG4584	PFAM Integrase catalytic
FY141_10670	COG0840	transmembrane signaling receptor activity
FY141_10685	COG0646	methionine synthase
FY141_10685	COG1410	methionine synthase
FY141_10700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_10730	COG1215	transferase activity, transferring glycosyl groups
FY141_10760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY141_10775	COG2346	COG2346, Truncated hemoglobins
FY141_10795	COG1309	transcriptional regulator
FY141_10810	COG0494	nUDIX hydrolase
FY141_10820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_10825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_10855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY141_10860	COG0830	nickel cation binding
FY141_10865	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY141_10880	COG0804	urea catabolic process
FY141_10885	COG1442	glycosyl transferase family 8
FY141_10890	COG3755	Protein conserved in bacteria
FY141_10900	COG0832	Belongs to the urease beta subunit family
FY141_10905	COG3813	Protein conserved in bacteria
FY141_10910	COG0831	urea catabolic process
FY141_10915	COG0829	nickel cation binding
FY141_10945	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY141_10960	COG0174	glutamine synthetase
FY141_10965	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_10970	COG0784	Response regulator, receiver
FY141_10970	COG2198	Histidine kinase
FY141_10970	COG5002	protein histidine kinase activity
FY141_10985	COG0726	polysaccharide deacetylase
FY141_11020	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY141_11095	COG0564	pseudouridine synthase activity
FY141_11105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY141_11115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY141_11140	COG0346	lactoylglutathione lyase activity
FY141_11150	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY141_11160	COG2832	Protein of unknown function (DUF454)
FY141_11165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY141_11170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_11175	COG4558	Periplasmic binding protein
FY141_11185	COG3721	Heme iron utilization protein
FY141_11200	COG3655	Transcriptional regulator
FY141_11225	COG2205	protein histidine kinase activity
FY141_11265	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_11270	COG4605	iron ion homeostasis
FY141_11275	COG4604	ABC transporter, ATP-binding protein
FY141_11280	COG0783	Belongs to the Dps family
FY141_11295	COG0840	transmembrane signaling receptor activity
FY141_11295	COG2972	Histidine kinase
FY141_11300	COG0656	L-ascorbic acid biosynthetic process
FY141_11305	COG2814	Major facilitator Superfamily
FY141_11315	COG0583	DNA-binding transcription factor activity
FY141_11320	COG0657	acetylesterase activity
FY141_11325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_11345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY141_11350	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY141_11355	COG0288	reversible hydration of carbon dioxide
FY141_11365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY141_11385	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY141_11390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY141_11395	COG0778	Nitroreductase
FY141_11400	COG2267	carboxylic ester hydrolase activity
FY141_11405	COG0251	oxidation-reduction process
FY141_11410	COG1335	isochorismatase
FY141_11415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_11425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_11440	COG1175	transmembrane transport
FY141_11445	COG0395	ABC-type sugar transport system, permease component
FY141_11450	COG3842	ATPase activity
FY141_11455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_11465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY141_11480	COG4608	Belongs to the ABC transporter superfamily
FY141_11485	COG0444	Belongs to the ABC transporter superfamily
FY141_11490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_11495	COG0601	transmembrane transport
FY141_11550	COG2159	amidohydrolase
FY141_11555	COG1960	acyl-CoA dehydrogenase activity
FY141_11585	COG0745	RESPONSE REGULATOR receiver
FY141_11595	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY141_11595	COG1902	pentaerythritol trinitrate reductase activity
FY141_11600	COG3842	ATPase activity
FY141_11610	COG1840	ABC-type Fe3 transport system, periplasmic component
FY141_11615	COG1840	ABC-type Fe3 transport system, periplasmic component
FY141_11620	COG0745	RESPONSE REGULATOR receiver
FY141_11630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY141_11635	COG0583	DNA-binding transcription factor activity
FY141_11640	COG1278	Cold shock
FY141_11680	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY141_11685	COG1309	transcriptional regulator
FY141_11690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_11695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY141_11705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY141_11710	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY141_11730	COG0583	DNA-binding transcription factor activity
FY141_11735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_11740	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY141_11745	COG4149	molybdate abc transporter
FY141_11750	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY141_11765	COG2022	thiamine diphosphate biosynthetic process
FY141_11780	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY141_11790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY141_11800	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY141_11820	COG1132	(ABC) transporter
FY141_11825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY141_11870	COG4166	transmembrane transport
FY141_11875	COG0601	transmembrane transport
FY141_11880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_11895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY141_11900	COG3142	Participates in the control of copper homeostasis
FY141_11905	COG2814	Major facilitator Superfamily
FY141_11920	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_11925	COG1737	Transcriptional regulator
FY141_11935	COG3842	ATPase activity
FY141_11945	COG0395	ABC-type sugar transport system, permease component
FY141_11965	COG2188	Transcriptional regulator
FY141_11970	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY141_11975	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY141_11980	COG1940	carbohydrate kinase activity
FY141_11990	COG0671	phosphoesterase, PA-phosphatase related
FY141_11995	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY141_12000	COG0156	8-amino-7-oxononanoate synthase activity
FY141_12010	COG0729	surface antigen
FY141_12020	COG0835	chemotaxis
FY141_12030	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY141_12035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY141_12040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY141_12045	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY141_12050	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY141_12055	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY141_12070	COG4974	Belongs to the 'phage' integrase family
FY141_12095	COG1280	lysine exporter protein (LysE YggA)
FY141_12105	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY141_12110	COG0567	Dehydrogenase, E1 component
FY141_12115	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY141_12120	COG0045	succinate-CoA ligase (ADP-forming) activity
FY141_12125	COG0039	L-malate dehydrogenase activity
FY141_12130	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY141_12180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY141_12185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY141_12190	COG0181	hydroxymethylbilane synthase activity
FY141_12230	COG1872	DUF167
FY141_12235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY141_12245	COG1217	gtp-binding protein TYPA
FY141_12250	COG0339	signal peptide processing
FY141_12255	COG1846	Transcriptional regulator
FY141_12265	COG0137	argininosuccinate synthase activity
FY141_12275	COG1280	lysine exporter protein (LysE YggA)
FY141_12280	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY141_12285	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY141_12295	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY141_12310	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY141_12315	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY141_12320	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY141_12330	COG4181	ATPase activity
FY141_12340	COG0670	Belongs to the BI1 family
FY141_12355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY141_12360	COG4133	protoheme IX ABC transporter activity
FY141_12365	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY141_12370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY141_12395	COG2917	probably involved in intracellular septation
FY141_12400	COG0552	protein localization to endoplasmic reticulum
FY141_12405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY141_12410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY141_12425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY141_12430	COG0287	Prephenate dehydrogenase
FY141_12430	COG1605	Chorismate mutase
FY141_12435	COG0228	four-way junction DNA binding
FY141_12440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY141_12445	COG0336	Belongs to the RNA methyltransferase TrmD family
FY141_12455	COG0335	large ribosomal subunit rRNA binding
FY141_12460	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY141_12465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_12480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY141_12500	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY141_12520	COG0488	(ABC) transporter
FY141_12530	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY141_12540	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY141_12545	COG0142	geranyltranstransferase activity
FY141_12550	COG2885	chlorophyll binding
FY141_12555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY141_12560	COG2223	nitrite transmembrane transporter activity
FY141_12565	COG1349	DNA-binding transcription factor activity
FY141_12570	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY141_12575	COG2197	response regulator
FY141_12580	COG1132	(ABC) transporter
FY141_12590	COG3459	Glycosyltransferase 36 associated
FY141_12595	COG1473	amidohydrolase
FY141_12600	COG0579	oxidoreductase
FY141_12610	COG0129	dihydroxy-acid dehydratase activity
FY141_12615	COG2084	Dehydrogenase
FY141_12620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY141_12625	COG0277	FAD linked oxidase domain protein
FY141_12630	COG2186	Transcriptional regulator
FY141_12640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY141_12645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY141_12650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY141_12655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY141_12665	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY141_12670	COG0495	leucyl-tRNA aminoacylation
FY141_12685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY141_12690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY141_12705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY141_12710	COG1946	Acyl-CoA thioesterase
FY141_12715	COG0347	Belongs to the P(II) protein family
FY141_12720	COG0004	ammonium transporteR
FY141_12725	COG1674	ftsk spoiiie
FY141_12730	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY141_12745	COG0745	RESPONSE REGULATOR receiver
FY141_12755	COG1329	Transcriptional regulator
FY141_12765	COG2270	Major facilitator Superfamily
FY141_12780	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_12795	COG0494	nUDIX hydrolase
FY141_12800	COG2861	carbohydrate metabolic process
FY141_12805	COG0793	Belongs to the peptidase S41A family
FY141_12815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY141_12820	COG0799	negative regulation of ribosome biogenesis
FY141_12825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY141_12830	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY141_12835	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY141_12840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY141_12855	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY141_12860	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY141_12885	COG0066	3-isopropylmalate dehydratase activity
FY141_12890	COG0473	3-isopropylmalate dehydrogenase activity
FY141_12895	COG1858	cytochrome C peroxidase
FY141_12900	COG1797	cobyrinic acid a,c-diamide synthase activity
FY141_12910	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY141_12975	COG1492	cobalamin metabolic process
FY141_12990	COG4948	Mandelate Racemase Muconate Lactonizing
FY141_12995	COG3254	rhamnose metabolic process
FY141_13000	COG0246	Mannitol dehydrogenase
FY141_13005	COG1063	alcohol dehydrogenase
FY141_13030	COG1129	ABC transporter
FY141_13035	COG2186	Transcriptional regulator
FY141_13040	COG2721	sulfolactate sulfo-lyase activity
FY141_13045	COG0138	bifunctional purine biosynthesis protein purh
FY141_13055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY141_13055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY141_13060	COG0501	Belongs to the peptidase M48B family
FY141_13080	COG0357	Ribosomal RNA small subunit methyltransferase G
FY141_13085	COG0445	tRNA wobble uridine modification
FY141_13090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY141_13095	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY141_13100	COG1981	membrane
FY141_13105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY141_13110	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY141_13115	COG0424	maF-like protein
FY141_13120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY141_13125	COG0237	dephospho-CoA kinase activity
FY141_13135	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY141_13140	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY141_13150	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY141_13175	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY141_13190	COG0135	phosphoribosylanthranilate isomerase activity
FY141_13195	COG0133	tryptophan synthase activity
FY141_13200	COG0159	tryptophan synthase activity
FY141_13205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY141_13220	COG1074	ATP-dependent DNA helicase activity
FY141_13230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY141_13235	COG0802	atpase or kinase
FY141_13240	COG2205	protein histidine kinase activity
FY141_13245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY141_13250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY141_13255	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY141_13255	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY141_13260	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY141_13265	COG0642	Histidine kinase
FY141_13270	COG0745	RESPONSE REGULATOR receiver
FY141_13275	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY141_13285	COG1652	LysM domain
FY141_13290	COG1072	(Pantothenic acid kinase))
FY141_13295	COG0140	phosphoribosyl-ATP diphosphatase activity
FY141_13300	COG0107	imidazoleglycerol-phosphate synthase activity
FY141_13305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY141_13310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY141_13320	COG0131	Imidazoleglycerol-phosphate dehydratase
FY141_13325	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY141_13330	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY141_13340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY141_13355	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY141_13365	COG1643	Atp-dependent helicase
FY141_13410	COG1940	carbohydrate kinase activity
FY141_13430	COG1072	(Pantothenic acid kinase))
FY141_13440	COG1780	Probably involved in ribonucleotide reductase function
FY141_13460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY141_13490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_13500	COG2813	Specifically methylates the guanine in position
FY141_13505	COG1185	polyribonucleotide nucleotidyltransferase activity
FY141_13510	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY141_13515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY141_13520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY141_13525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY141_13525	COG3064	Membrane
FY141_13540	COG0779	Required for maturation of 30S ribosomal subunits
FY141_13545	COG2814	Major facilitator Superfamily
FY141_13555	COG2951	lytic endotransglycosylase activity
FY141_13560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY141_13570	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY141_13575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY141_13590	COG2816	NAD+ diphosphatase activity
FY141_13595	COG0077	Prephenate dehydratase
FY141_13595	COG1605	Chorismate mutase
FY141_13600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY141_13605	COG3474	cytochrome
FY141_13615	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY141_13620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY141_13625	COG1278	Cold shock
FY141_13630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY141_13640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY141_13640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY141_13645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY141_13675	COG2900	Belongs to the SlyX family
FY141_13685	COG0484	heat shock protein binding
FY141_13690	COG0443	Heat shock 70 kDa protein
FY141_13705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY141_13710	COG1744	ABC transporter substrate-binding protein PnrA-like
FY141_13715	COG3845	ABC transporter
FY141_13720	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY141_13725	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY141_13730	COG0295	cytidine deaminase activity
FY141_13735	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY141_13740	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY141_13745	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY141_13755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY141_13760	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY141_13765	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY141_13775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY141_13780	COG1845	cytochrome c oxidase, subunit III
FY141_13785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY141_13790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY141_13795	COG0477	Major facilitator Superfamily
FY141_13800	COG0069	glutamate synthase activity
FY141_13800	COG0067	glutamate synthase
FY141_13800	COG0070	glutamate synthase
FY141_13805	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY141_13820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY141_13830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY141_13860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_13880	COG0848	biopolymer transport protein
FY141_13890	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY141_13905	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY141_13910	COG3454	Phosphonate metabolism
FY141_13915	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY141_13920	COG3639	organic phosphonate transmembrane transporter activity
FY141_13925	COG3639	organic phosphonate transmembrane transporter activity
FY141_13935	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY141_13945	COG4778	phosphonate C-P lyase system protein PhnL
FY141_13950	COG4107	phosphonate C-P lyase system protein PhnK
FY141_13955	COG3627	carbon phosphorus lyase activity
FY141_13960	COG3626	phosphonate metabolism
FY141_13965	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY141_13970	COG3624	Phosphonate C-P lyase system protein PhnG
FY141_13975	COG2188	Transcriptional regulator
FY141_13980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY141_13985	COG0837	glucose binding
FY141_13990	COG1803	Methylglyoxal synthase
FY141_13995	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY141_14000	COG4166	transmembrane transport
FY141_14005	COG4174	ABC transporter (Permease)
FY141_14010	COG4239	(ABC) transporter, permease
FY141_14015	COG4172	Belongs to the ABC transporter superfamily
FY141_14020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_14025	COG0174	glutamine synthetase
FY141_14030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_14035	COG3265	gluconokinase activity
FY141_14040	COG1174	glycine betaine transport
FY141_14045	COG1125	glycine betaine transport
FY141_14050	COG1174	glycine betaine transport
FY141_14055	COG1732	Glycine betaine
FY141_14065	COG1959	2 iron, 2 sulfur cluster binding
FY141_14070	COG1840	ABC-type Fe3 transport system, periplasmic component
FY141_14080	COG4269	membrane
FY141_14095	COG0697	spore germination
FY141_14110	COG0791	NLP P60 protein
FY141_14120	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY141_14125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY141_14160	COG4964	Belongs to the GSP D family
FY141_14205	COG3422	double-strand break repair
FY141_14210	COG3757	hydrolase, family 25
FY141_14215	COG0697	spore germination
FY141_14220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY141_14235	COG0492	ferredoxin-NADP+ reductase activity
FY141_14250	COG0481	GTPase activity
FY141_14255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY141_14270	COG1396	sequence-specific DNA binding
FY141_14285	COG1917	Cupin 2, conserved barrel domain protein
FY141_14285	COG2169	Transcriptional regulator
FY141_14290	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY141_14315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY141_14320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY141_14325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY141_14335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY141_14340	COG0072	phenylalanine-tRNA ligase activity
FY141_14340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY141_14345	COG0667	Aldo Keto reductase
FY141_14365	COG4977	sequence-specific DNA binding
FY141_14390	COG1570	exodeoxyribonuclease VII activity
FY141_14395	COG4948	Mandelate Racemase Muconate Lactonizing
FY141_14405	COG1846	Transcriptional regulator
FY141_14415	COG2309	aminopeptidase activity
FY141_14425	COG1393	Belongs to the ArsC family
FY141_14440	COG1309	transcriptional regulator
FY141_14450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY141_14450	COG0519	Catalyzes the synthesis of GMP from XMP
FY141_14465	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY141_14495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY141_14505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY141_14515	COG1968	undecaprenyl-diphosphatase activity
FY141_14530	COG0284	orotidine-5'-phosphate decarboxylase activity
FY141_14540	COG3963	phosphatidate phosphatase activity
FY141_14550	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY141_14555	COG0792	nuclease activity
FY141_14570	COG1175	transmembrane transport
FY141_14575	COG0395	ABC-type sugar transport system, permease component
FY141_14580	COG3842	ATPase activity
FY141_14590	COG0189	ligase activity
FY141_14600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY141_14605	COG1280	lysine exporter protein (LysE YggA)
FY141_14610	COG0756	dUTP diphosphatase activity
FY141_14615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY141_14620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY141_14635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY141_14640	COG2226	methyltransferase
FY141_14645	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY141_14650	COG1024	Enoyl-CoA hydratase
FY141_14655	COG0268	Binds directly to 16S ribosomal RNA
FY141_14680	COG0640	Transcriptional regulator
FY141_14720	COG4178	(ABC) transporter
FY141_14745	COG1082	Xylose isomerase domain protein TIM barrel
FY141_14750	COG0572	uridine kinase
FY141_14760	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_14765	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_14770	COG1129	ABC transporter
FY141_14790	COG3284	Transcriptional regulator
FY141_14795	COG1063	alcohol dehydrogenase
FY141_14805	COG0110	maltose O-acetyltransferase activity
FY141_14810	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY141_14835	COG0488	(ABC) transporter
FY141_14840	COG5265	(ABC) transporter
FY141_14845	COG3181	Tripartite tricarboxylate transporter family receptor
FY141_14850	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY141_14860	COG3237	CsbD-like
FY141_14880	COG0395	ABC-type sugar transport system, permease component
FY141_14885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY141_14895	COG0483	inositol monophosphate 1-phosphatase activity
FY141_14905	COG0405	Gamma-glutamyltransferase
FY141_14910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_14915	COG0601	transmembrane transport
FY141_14920	COG0747	negative chemotaxis
FY141_14925	COG2186	Transcriptional regulator
FY141_14935	COG4948	Mandelate Racemase Muconate Lactonizing
FY141_14940	COG4172	Belongs to the ABC transporter superfamily
FY141_14945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_14950	COG0601	transmembrane transport
FY141_14955	COG0747	negative chemotaxis
FY141_14960	COG2186	Transcriptional regulator
FY141_14970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_14975	COG2223	nitrite transmembrane transporter activity
FY141_14985	COG3383	formate dehydrogenase (NAD+) activity
FY141_15005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY141_15020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY141_15030	COG0765	amino acid transport
FY141_15035	COG0765	amino acid transport
FY141_15040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_15055	COG3938	Belongs to the proline racemase family
FY141_15065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_15075	COG0765	amino acid transport
FY141_15090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY141_15095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_15105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY141_15110	COG0784	Response regulator, receiver
FY141_15125	COG0842	Transport permease protein
FY141_15130	COG0842	Transport permease protein
FY141_15130	COG1129	ABC transporter
FY141_15135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_15140	COG1486	melibiose metabolic process
FY141_15145	COG4172	Belongs to the ABC transporter superfamily
FY141_15150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_15155	COG0601	transmembrane transport
FY141_15160	COG0747	negative chemotaxis
FY141_15165	COG1486	melibiose metabolic process
FY141_15190	COG1940	carbohydrate kinase activity
FY141_15195	COG2182	Extracellular solute-binding protein
FY141_15200	COG1175	transmembrane transport
FY141_15205	COG0395	ABC-type sugar transport system, permease component
FY141_15210	COG0165	Argininosuccinate lyase
FY141_15215	COG3842	ATPase activity
FY141_15220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_15225	COG3119	arylsulfatase activity
FY141_15235	COG0583	DNA-binding transcription factor activity
FY141_15240	COG1120	ATPase activity
FY141_15245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_15250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_15260	COG4774	siderophore transport
FY141_15270	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY141_15285	COG2205	protein histidine kinase activity
FY141_15290	COG0745	RESPONSE REGULATOR receiver
FY141_15295	COG1566	PFAM secretion protein HlyD family protein
FY141_15310	COG1392	Phosphate transport regulator
FY141_15315	COG0306	phosphate transporter
FY141_15320	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY141_15330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY141_15340	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_15345	COG5001	Diguanylate cyclase
FY141_15345	COG3300	MHYT domain
FY141_15365	COG2186	Transcriptional regulator
FY141_15370	COG0601	transmembrane transport
FY141_15375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_15380	COG0444	Belongs to the ABC transporter superfamily
FY141_15390	COG3842	ATPase activity
FY141_15395	COG0395	ABC-type sugar transport system, permease component
FY141_15410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY141_15410	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY141_15415	COG1609	Transcriptional regulator
FY141_15425	COG0210	DNA helicase
FY141_15430	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY141_15435	COG1088	dTDP-glucose 4,6-dehydratase activity
FY141_15440	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY141_15445	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY141_15460	COG3754	Rhamnan synthesis protein F
FY141_15465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY141_15485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY141_15495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY141_15500	COG1216	Glycosyl transferase, family 2
FY141_15500	COG1442	glycosyl transferase family 8
FY141_15515	COG1132	(ABC) transporter
FY141_15525	COG0583	DNA-binding transcription factor activity
FY141_15530	COG0667	Aldo Keto reductase
FY141_15550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY141_15565	COG0300	oxidoreductase activity
FY141_15570	COG0584	glycerophosphoryl diester phosphodiesterase
FY141_15575	COG1940	carbohydrate kinase activity
FY141_15585	COG3712	iron ion homeostasis
FY141_15590	COG4774	siderophore transport
FY141_15595	COG2814	Major facilitator Superfamily
FY141_15615	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY141_15625	COG3842	ATPase activity
FY141_15630	COG1175	transmembrane transport
FY141_15635	COG0395	ABC-type sugar transport system, permease component
FY141_15640	COG1609	Transcriptional regulator
FY141_15650	COG0673	inositol 2-dehydrogenase activity
FY141_15655	COG1082	Xylose isomerase domain protein TIM barrel
FY141_15670	COG1609	Transcriptional regulator
FY141_15675	COG0183	Belongs to the thiolase family
FY141_15680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY141_15690	COG1414	Transcriptional regulator
FY141_15705	COG0583	DNA-binding transcription factor activity
FY141_15715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY141_15720	COG3485	protocatechuate 3,4-dioxygenase
FY141_15725	COG3485	protocatechuate 3,4-dioxygenase
FY141_15730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY141_15735	COG0765	amino acid transport
FY141_15740	COG0765	amino acid transport
FY141_15745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_15750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_15755	COG1126	abc transporter atp-binding protein
FY141_15760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY141_15765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY141_15790	COG4172	Belongs to the ABC transporter superfamily
FY141_15795	COG0747	negative chemotaxis
FY141_15805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_15820	COG0683	leucine binding
FY141_15835	COG0411	ABC transporter
FY141_15850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_15855	COG3962	Belongs to the TPP enzyme family
FY141_15865	COG3718	enzyme involved in inositol metabolism
FY141_15875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY141_15880	COG1609	Transcriptional regulator
FY141_15885	COG1846	Transcriptional regulator
FY141_15895	COG0523	cobalamin synthesis protein
FY141_15935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY141_15955	COG0800	Aldolase
FY141_15960	COG2954	triphosphatase activity
FY141_15970	COG1054	Belongs to the UPF0176 family
FY141_15975	COG5001	Diguanylate cyclase
FY141_15975	COG3300	MHYT domain
FY141_15985	COG2011	ABC-type metal ion transport system permease component
FY141_15990	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY141_15995	COG0778	Nitroreductase
FY141_16005	COG2115	Belongs to the xylose isomerase family
FY141_16010	COG1070	Carbohydrate kinase
FY141_16015	COG1609	Transcriptional regulator
FY141_16035	COG1309	transcriptional regulator
FY141_16040	COG1253	flavin adenine dinucleotide binding
FY141_16045	COG3273	potassium ion transport
FY141_16045	COG0471	metal ion transport
FY141_16050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY141_16055	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY141_16060	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY141_16070	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY141_16075	COG1121	(ABC) transporter
FY141_16080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY141_16085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY141_16095	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_16100	COG1414	Transcriptional regulator
FY141_16105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY141_16125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY141_16175	COG0395	ABC-type sugar transport system, permease component
FY141_16180	COG1175	transmembrane transport
FY141_16190	COG2390	Transcriptional regulator
FY141_16195	COG4172	Belongs to the ABC transporter superfamily
FY141_16200	COG1473	amidohydrolase
FY141_16210	COG0601	transmembrane transport
FY141_16215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_16225	COG0693	protein deglycase activity
FY141_16230	COG0154	amidase activity
FY141_16235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_16245	COG0747	negative chemotaxis
FY141_16250	COG0583	DNA-binding transcription factor activity
FY141_16255	COG4608	Belongs to the ABC transporter superfamily
FY141_16260	COG0444	Belongs to the ABC transporter superfamily
FY141_16265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_16270	COG0601	transmembrane transport
FY141_16275	COG0747	negative chemotaxis
FY141_16290	COG1473	amidohydrolase
FY141_16295	COG2814	Major facilitator Superfamily
FY141_16300	COG0583	DNA-binding transcription factor activity
FY141_16305	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY141_16315	COG3842	ATPase activity
FY141_16325	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_16335	COG1609	Transcriptional regulator
FY141_16340	COG0583	DNA-binding transcription factor activity
FY141_16345	COG1960	acyl-CoA dehydrogenase activity
FY141_16350	COG1629	transport
FY141_16350	COG4774	siderophore transport
FY141_16360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_16370	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_16375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_16385	COG2375	cellular response to nickel ion
FY141_16395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY141_16400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY141_16400	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY141_16410	COG1169	isochorismate synthase
FY141_16415	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY141_16420	COG1535	isochorismatase
FY141_16420	COG3433	isochorismatase activity
FY141_16425	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_16440	COG3005	denitrification pathway
FY141_16450	COG0243	molybdopterin cofactor binding
FY141_16465	COG4459	periplasmic nitrate reductase
FY141_16500	COG0826	peptidase U32
FY141_16510	COG3189	MarR family transcriptional regulator
FY141_16515	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY141_16545	COG3256	nitric oxide reductase
FY141_16550	COG0714	Associated with various cellular activities
FY141_16610	COG0673	inositol 2-dehydrogenase activity
FY141_16620	COG1609	Transcriptional regulator
FY141_16625	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_16630	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_16635	COG1129	ABC transporter
FY141_16640	COG1879	ABC-type sugar transport system periplasmic component
FY141_16650	COG0583	DNA-binding transcription factor activity
FY141_16665	COG1609	Transcriptional regulator
FY141_16670	COG0673	inositol 2-dehydrogenase activity
FY141_16680	COG1653	transport
FY141_16685	COG1175	transmembrane transport
FY141_16690	COG0395	ABC-type sugar transport system, permease component
FY141_16695	COG3842	ATPase activity
FY141_16710	COG1253	flavin adenine dinucleotide binding
FY141_16735	COG3300	MHYT domain
FY141_16735	COG5001	Diguanylate cyclase
FY141_16865	COG0477	Major facilitator Superfamily
FY141_16885	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_16895	COG1879	ABC-type sugar transport system periplasmic component
FY141_16905	COG1063	alcohol dehydrogenase
FY141_16920	COG1136	(ABC) transporter
FY141_16935	COG1309	transcriptional regulator
FY141_16955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY141_16965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY141_16965	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY141_16975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_16980	COG0047	phosphoribosylformylglycinamidine synthase activity
FY141_16990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_16995	COG1012	belongs to the aldehyde dehydrogenase family
FY141_17000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_17010	COG3448	diguanylate cyclase activity
FY141_17010	COG4175	Glycine betaine
FY141_17020	COG4176	ABC-type proline glycine betaine transport system permease component
FY141_17025	COG3938	Belongs to the proline racemase family
FY141_17030	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY141_17065	COG1733	regulation of RNA biosynthetic process
FY141_17115	COG0477	Major facilitator Superfamily
FY141_17125	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY141_17130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY141_17145	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_17155	COG0395	ABC-type sugar transport system, permease component
FY141_17180	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_17185	COG1349	DNA-binding transcription factor activity
FY141_17190	COG1069	ribulokinase activity
FY141_17210	COG1940	carbohydrate kinase activity
FY141_17225	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_17230	COG1177	transmembrane transport
FY141_17240	COG3842	ATPase activity
FY141_17295	COG1136	(ABC) transporter
FY141_17295	COG0577	efflux transmembrane transporter activity
FY141_17320	COG1845	cytochrome c oxidase, subunit III
FY141_17325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY141_17330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY141_17335	COG3474	cytochrome
FY141_17365	COG3842	ATPase activity
FY141_17370	COG0395	ABC-type sugar transport system, permease component
FY141_17375	COG1175	transmembrane transport
FY141_17380	COG1653	transport
FY141_17385	COG1012	belongs to the aldehyde dehydrogenase family
FY141_17390	COG1024	Enoyl-CoA hydratase
FY141_17410	COG4702	Belongs to the UPF0303 family
FY141_17415	COG1629	transport
FY141_17415	COG4774	siderophore transport
FY141_17420	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY141_17425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_17430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_17435	COG1120	ATPase activity
FY141_17450	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY141_17460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY141_17465	COG1177	transmembrane transport
FY141_17470	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_17475	COG3842	ATPase activity
FY141_17500	COG1335	isochorismatase
FY141_17515	COG0583	DNA-binding transcription factor activity
FY141_17520	COG2318	DinB family
FY141_17545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY141_17575	COG0778	Nitroreductase
FY141_17595	COG0277	FAD linked oxidase domain protein
FY141_17615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_17620	COG4172	Belongs to the ABC transporter superfamily
FY141_17630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_17640	COG0431	NADPH-dependent FMN reductase
FY141_17660	COG1522	sequence-specific DNA binding
FY141_17665	COG2376	Dihydroxyacetone kinase
FY141_17675	COG4221	oxidoreductase activity
FY141_17680	COG0625	glutathione transferase activity
FY141_17690	COG1566	PFAM secretion protein HlyD family protein
FY141_17700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY141_17705	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY141_17720	COG0534	Mate efflux family protein
FY141_17755	COG1733	regulation of RNA biosynthetic process
FY141_17765	COG0577	efflux transmembrane transporter activity
FY141_17765	COG1136	(ABC) transporter
FY141_17770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_17780	COG0745	RESPONSE REGULATOR receiver
FY141_17800	COG3209	COG3209 Rhs family protein
FY141_17830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_17855	COG3177	Filamentation induced by cAMP protein fic
FY141_17870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_17875	COG4597	amino acid ABC transporter
FY141_17880	COG0765	amino acid transport
FY141_17905	COG0747	negative chemotaxis
FY141_17910	COG0601	transmembrane transport
FY141_17915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_17920	COG0444	Belongs to the ABC transporter superfamily
FY141_17925	COG4608	Belongs to the ABC transporter superfamily
FY141_17945	COG4213	ABC transporter substrate-binding protein
FY141_17950	COG1129	ABC transporter
FY141_17955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_17970	COG0667	Aldo Keto reductase
FY141_17995	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_18000	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_18005	COG1129	ABC transporter
FY141_18015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_18025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_18035	COG0747	negative chemotaxis
FY141_18040	COG0747	negative chemotaxis
FY141_18045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_18055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_18060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_18065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY141_18075	COG0405	Gamma-glutamyltransferase
FY141_18105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_18110	COG0436	Aminotransferase
FY141_18125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_18130	COG0765	amino acid transport
FY141_18140	COG1126	abc transporter atp-binding protein
FY141_18150	COG2186	Transcriptional regulator
FY141_18170	COG1846	Transcriptional regulator
FY141_18175	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_18185	COG0583	DNA-binding transcription factor activity
FY141_18220	COG0583	DNA-binding transcription factor activity
FY141_18240	COG1280	lysine exporter protein (LysE YggA)
FY141_18245	COG3920	Histidine kinase
FY141_18270	COG0753	catalase activity
FY141_18290	COG1278	Cold shock
FY141_18330	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_18335	COG1902	pentaerythritol trinitrate reductase activity
FY141_18340	COG4221	oxidoreductase activity
FY141_18345	COG1309	transcriptional regulator
FY141_18360	COG1280	lysine exporter protein (LysE YggA)
FY141_18370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY141_18415	COG0739	heme binding
FY141_18415	COG0741	lytic transglycosylase activity
FY141_18415	COG1196	nuclear chromosome segregation
FY141_18420	COG0542	response to heat
FY141_18430	COG2890	protein-(glutamine-N5) methyltransferase activity
FY141_18435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY141_18445	COG0527	aspartate kinase activity
FY141_18460	COG0019	diaminopimelate decarboxylase activity
FY141_18475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY141_18495	COG0784	Response regulator, receiver
FY141_18510	COG1522	sequence-specific DNA binding
FY141_18520	COG1116	anion transmembrane transporter activity
FY141_18525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_18530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY141_18535	COG1012	belongs to the aldehyde dehydrogenase family
FY141_18540	COG0583	DNA-binding transcription factor activity
FY141_18545	COG0435	Glutathione S-transferase
FY141_18560	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY141_18565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY141_18570	COG0189	ligase activity
FY141_18590	COG0693	protein deglycase activity
FY141_18620	COG3685	Protein conserved in bacteria
FY141_18625	COG4993	Dehydrogenase
FY141_18640	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_18645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY141_18690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_18705	COG0246	Mannitol dehydrogenase
FY141_18710	COG4608	Belongs to the ABC transporter superfamily
FY141_18715	COG0444	Belongs to the ABC transporter superfamily
FY141_18720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_18725	COG0601	transmembrane transport
FY141_18730	COG0747	negative chemotaxis
FY141_18740	COG4221	oxidoreductase activity
FY141_18770	COG0539	negative regulation of cytoplasmic translation
FY141_18775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY141_18805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY141_18810	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY141_18840	COG1294	oxidase, subunit
FY141_18850	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY141_18855	COG4988	ABC transporter
FY141_18865	COG1063	alcohol dehydrogenase
FY141_18870	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_18875	COG2084	Dehydrogenase
FY141_18885	COG1522	sequence-specific DNA binding
FY141_18890	COG1794	racemase activity, acting on amino acids and derivatives
FY141_18905	COG0058	SHG alpha-glucan phosphorylase activity
FY141_18910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY141_18915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY141_18920	COG0297	glycogen (starch) synthase activity
FY141_18925	COG0033	Phosphoglucomutase
FY141_18930	COG1523	belongs to the glycosyl hydrolase 13 family
FY141_18960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY141_18960	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY141_18975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_18980	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY141_19000	COG1215	transferase activity, transferring glycosyl groups
FY141_19005	COG2327	Polysaccharide pyruvyl transferase
FY141_19010	COG0463	Glycosyl transferase, family 2
FY141_19015	COG2244	polysaccharide biosynthetic process
FY141_19020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY141_19025	COG2273	Hydrolase Family 16
FY141_19030	COG0438	transferase activity, transferring glycosyl groups
FY141_19035	COG1215	transferase activity, transferring glycosyl groups
FY141_19040	COG1215	transferase activity, transferring glycosyl groups
FY141_19045	COG1215	transferase activity, transferring glycosyl groups
FY141_19050	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY141_19055	COG3206	protein involved in exopolysaccharide biosynthesis
FY141_19055	COG0489	protein tyrosine kinase activity
FY141_19060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY141_19065	COG0784	Response regulator, receiver
FY141_19065	COG4191	Histidine kinase
FY141_19080	COG4176	ABC-type proline glycine betaine transport system permease component
FY141_19085	COG4175	Glycine betaine
FY141_19085	COG3448	diguanylate cyclase activity
FY141_19100	COG0564	pseudouridine synthase activity
FY141_19105	COG0500	methyltransferase
FY141_19115	COG2133	pyrroloquinoline quinone binding
FY141_19125	COG2197	response regulator
FY141_19130	COG4585	Histidine kinase
FY141_19135	COG1879	ABC-type sugar transport system periplasmic component
FY141_19140	COG1129	ABC transporter
FY141_19145	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_19155	COG3386	PFAM SMP-30 Gluconolaconase
FY141_19160	COG2137	regulation of response to DNA damage stimulus
FY141_19165	COG3474	cytochrome
FY141_19175	COG1120	ATPase activity
FY141_19190	COG4774	siderophore transport
FY141_19195	COG0583	DNA-binding transcription factor activity
FY141_19205	COG2194	sulfuric ester hydrolase activity
FY141_19220	COG0477	Major facilitator Superfamily
FY141_19245	COG0673	inositol 2-dehydrogenase activity
FY141_19250	COG0697	spore germination
FY141_19260	COG0010	Belongs to the arginase family
FY141_19275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY141_19280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY141_19285	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY141_19290	COG0156	8-amino-7-oxononanoate synthase activity
FY141_19295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY141_19345	COG0671	phosphoesterase, PA-phosphatase related
FY141_19350	COG0745	RESPONSE REGULATOR receiver
FY141_19355	COG2205	protein histidine kinase activity
FY141_19365	COG0477	Major facilitator Superfamily
FY141_19370	COG0583	DNA-binding transcription factor activity
FY141_19390	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY141_19405	COG0346	lactoylglutathione lyase activity
FY141_19410	COG0583	DNA-binding transcription factor activity
FY141_19440	COG1215	transferase activity, transferring glycosyl groups
FY141_19460	COG0840	transmembrane signaling receptor activity
FY141_19475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_19490	COG2828	Protein conserved in bacteria
FY141_19495	COG0583	DNA-binding transcription factor activity
FY141_19500	COG1846	Transcriptional regulator
FY141_19525	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_19530	COG1309	transcriptional regulator
FY141_19535	COG2207	Transcriptional regulator
FY141_19550	COG1566	PFAM secretion protein HlyD family protein
FY141_19570	COG0395	ABC-type sugar transport system, permease component
FY141_19575	COG4166	transmembrane transport
FY141_19580	COG0601	transmembrane transport
FY141_19585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_19590	COG4172	Belongs to the ABC transporter superfamily
FY141_19630	COG0402	S-adenosylhomocysteine deaminase activity
FY141_19635	COG1228	amidohydrolase
FY141_19640	COG2986	histidine ammonia-lyase
FY141_19650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY141_19680	COG1192	Involved in chromosome partitioning
FY141_19685	COG1475	DNA binding
FY141_19690	COG1414	Transcriptional regulator
FY141_19710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY141_19715	COG4771	TonB-dependent receptor
FY141_19725	COG0366	Alpha amylase catalytic
FY141_19730	COG4770	biotin carboxylase activity
FY141_19735	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY141_19740	COG4336	lyase activity
FY141_19745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY141_19750	COG1914	H( )-stimulated, divalent metal cation uptake system
FY141_19755	COG1802	Transcriptional regulator
FY141_19760	COG3707	response regulator
FY141_19770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY141_19775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_19780	COG1116	anion transmembrane transporter activity
FY141_19785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY141_19795	COG0243	molybdopterin cofactor binding
FY141_19800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY141_19800	COG1648	precorrin-2 dehydrogenase activity
FY141_19815	COG3842	ATPase activity
FY141_19830	COG0395	ABC-type sugar transport system, permease component
FY141_19845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY141_19860	COG0071	Belongs to the small heat shock protein (HSP20) family
FY141_19905	COG1879	ABC-type sugar transport system periplasmic component
FY141_19910	COG1129	ABC transporter
FY141_19915	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_19925	COG0667	Aldo Keto reductase
FY141_19930	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY141_19935	COG1830	Aldolase
FY141_19940	COG1070	Carbohydrate kinase
FY141_19945	COG0840	transmembrane signaling receptor activity
FY141_19960	COG0436	Aminotransferase
FY141_19970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY141_19980	COG3842	ATPase activity
FY141_19985	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY141_19990	COG1984	allophanate hydrolase subunit 2
FY141_19995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY141_20005	COG0439	Biotin carboxylase
FY141_20010	COG0511	ligase activity, forming carbon-carbon bonds
FY141_20015	COG0697	spore germination
FY141_20020	COG0697	spore germination
FY141_20035	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY141_20050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY141_20055	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_20060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY141_20065	COG4221	oxidoreductase activity
FY141_20070	COG0765	amino acid transport
FY141_20075	COG0765	amino acid transport
FY141_20085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_20090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY141_20095	COG1063	alcohol dehydrogenase
FY141_20110	COG1304	FMN binding
FY141_20135	COG3842	ATPase activity
FY141_20145	COG0395	ABC-type sugar transport system, permease component
FY141_20150	COG1175	transmembrane transport
FY141_20165	COG2186	Transcriptional regulator
FY141_20170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY141_20175	COG0488	(ABC) transporter
FY141_20190	COG2307	Protein conserved in bacteria
FY141_20190	COG2308	Evidence 4 Homologs of previously reported genes of
FY141_20230	COG1454	alcohol dehydrogenase
FY141_20235	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY141_20245	COG0747	negative chemotaxis
FY141_20250	COG0601	transmembrane transport
FY141_20255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_20265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_20310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY141_20335	COG1082	Xylose isomerase domain protein TIM barrel
FY141_20340	COG0673	inositol 2-dehydrogenase activity
FY141_20345	COG1082	Xylose isomerase domain protein TIM barrel
FY141_20365	COG1609	Transcriptional regulator
FY141_20370	COG2986	histidine ammonia-lyase
FY141_20375	COG4175	Glycine betaine
FY141_20375	COG0517	IMP dehydrogenase activity
FY141_20380	COG4176	ABC-type proline glycine betaine transport system permease component
FY141_20420	COG2186	Transcriptional regulator
FY141_20425	COG1027	Aspartate ammonia-lyase
FY141_20435	COG0252	asparaginase activity
FY141_20445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY141_20450	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY141_20455	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY141_20460	COG2205	protein histidine kinase activity
FY141_20475	COG0069	glutamate synthase activity
FY141_20475	COG0070	glutamate synthase
FY141_20475	COG0067	glutamate synthase
FY141_20490	COG2205	protein histidine kinase activity
FY141_20505	COG2951	lytic endotransglycosylase activity
FY141_20510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY141_20535	COG0330	HflC and HflK could
FY141_20540	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY141_20545	COG0737	Belongs to the 5'-nucleotidase family
FY141_20555	COG5310	Homospermidine synthase
FY141_20565	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY141_20570	COG1164	Oligoendopeptidase f
FY141_20575	COG2204	response regulator
FY141_20580	COG3108	Peptidase M15
FY141_20585	COG0469	pyruvate kinase activity
FY141_20605	COG3750	Belongs to the UPF0335 family
FY141_20610	COG0457	Tetratricopeptide repeat
FY141_20615	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY141_20620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY141_20625	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY141_20655	COG0483	inositol monophosphate 1-phosphatase activity
FY141_20675	COG1132	(ABC) transporter
FY141_20680	COG0254	rRNA binding
FY141_20700	COG3588	fructose-bisphosphate aldolase
FY141_20705	COG0126	phosphoglycerate kinase activity
FY141_20745	COG1253	flavin adenine dinucleotide binding
FY141_20755	COG1692	metallophosphoesterase
FY141_20770	COG0217	transcriptional regulatory protein
FY141_20775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_20780	COG0840	transmembrane signaling receptor activity
FY141_20785	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY141_20790	COG0632	four-way junction helicase activity
FY141_20795	COG2255	four-way junction helicase activity
FY141_20810	COG0494	nUDIX hydrolase
FY141_20820	COG0824	Thioesterase
FY141_20840	COG0823	Involved in the tonB-independent uptake of proteins
FY141_20845	COG2885	chlorophyll binding
FY141_20855	COG0037	tRNA processing
FY141_20860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY141_20865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY141_20880	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY141_20895	COG0482	sulfurtransferase activity
FY141_20925	COG2835	tetraacyldisaccharide 4'-kinase activity
FY141_20930	COG2373	Large extracellular alpha-helical protein
FY141_20935	COG4953	penicillin-binding protein 1C
FY141_20945	COG1473	amidohydrolase
FY141_20950	COG1686	Belongs to the peptidase S11 family
FY141_20955	COG0523	cobalamin synthesis protein
FY141_20960	COG0425	Belongs to the sulfur carrier protein TusA family
FY141_20960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY141_20965	COG3034	peptidoglycan biosynthetic process
FY141_20970	COG0825	malonyl-CoA metabolic process
FY141_20975	COG4974	Belongs to the 'phage' integrase family
FY141_20985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY141_20990	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY141_21030	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY141_21035	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY141_21055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY141_21060	COG2226	methyltransferase
FY141_21065	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY141_21070	COG0287	Prephenate dehydrogenase
FY141_21080	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY141_21100	COG2884	Cell division ATP-binding protein ftsE
FY141_21135	COG0165	Argininosuccinate lyase
FY141_21140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY141_21150	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY141_21160	COG2086	electron transfer activity
FY141_21170	COG2096	Adenosyltransferase
FY141_21180	COG0300	oxidoreductase activity
FY141_21190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY141_21200	COG1396	sequence-specific DNA binding
FY141_21200	COG3800	Transcriptional regulator
FY141_21205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY141_21210	COG0625	glutathione transferase activity
FY141_21225	COG4770	biotin carboxylase activity
FY141_21230	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY141_21230	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY141_21235	COG0346	lactoylglutathione lyase activity
FY141_21250	COG4213	ABC transporter substrate-binding protein
FY141_21255	COG4214	carbohydrate transport
FY141_21260	COG1129	ABC transporter
FY141_21265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY141_21275	COG1396	sequence-specific DNA binding
FY141_21330	COG3833	ABC-type maltose transport systems, permease component
FY141_21335	COG3842	ATPase activity
FY141_21350	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY141_21350	COG2273	Hydrolase Family 16
FY141_21355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY141_21370	COG0438	transferase activity, transferring glycosyl groups
FY141_21375	COG0438	transferase activity, transferring glycosyl groups
FY141_21395	COG0489	protein tyrosine kinase activity
FY141_21395	COG3206	protein involved in exopolysaccharide biosynthesis
FY141_21405	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY141_21420	COG2244	polysaccharide biosynthetic process
FY141_21485	COG0697	spore germination
FY141_21490	COG0653	protein targeting
FY141_21495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY141_21500	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY141_21510	COG0494	nUDIX hydrolase
FY141_21525	COG2226	methyltransferase
FY141_21530	COG1040	competence protein
FY141_21540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY141_21550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY141_21565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY141_21570	COG4150	thiosulfate binding
FY141_21580	COG4208	sulfate ABC transporter
FY141_21585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY141_21590	COG4335	DNA alkylation repair
FY141_21605	COG5001	Diguanylate cyclase
FY141_21610	COG2264	protein methyltransferase activity
FY141_21625	COG3254	rhamnose metabolic process
FY141_21630	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_21635	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_21640	COG1129	ABC transporter
FY141_21650	COG1349	DNA-binding transcription factor activity
FY141_21655	COG3347	Dehydrogenase
FY141_21655	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_21660	COG4952	isomerase
FY141_21665	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY141_21670	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY141_21690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY141_21695	COG1960	acyl-CoA dehydrogenase activity
FY141_21705	COG0183	Belongs to the thiolase family
FY141_21710	COG1960	acyl-CoA dehydrogenase activity
FY141_21720	COG0022	dehydrogenase e1 component
FY141_21730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY141_21735	COG2391	methyltransferase activity
FY141_21745	COG0640	Transcriptional regulator
FY141_21750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY141_21750	COG3453	Protein conserved in bacteria
FY141_21760	COG0300	oxidoreductase activity
FY141_21775	COG2186	Transcriptional regulator
FY141_21785	COG0601	transmembrane transport
FY141_21795	COG0444	Belongs to the ABC transporter superfamily
FY141_21800	COG4608	Belongs to the ABC transporter superfamily
FY141_21930	COG2369	cell adhesion
FY141_21935	COG4383	Mu-like prophage protein gp29
FY141_21940	COG4373	Mu-like prophage FluMu protein gp28
FY141_22075	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_22080	COG1733	regulation of RNA biosynthetic process
FY141_22090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22115	COG1473	amidohydrolase
FY141_22120	COG0747	negative chemotaxis
FY141_22135	COG4166	transmembrane transport
FY141_22140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22145	COG0583	DNA-binding transcription factor activity
FY141_22155	COG0667	Aldo Keto reductase
FY141_22165	COG0444	Belongs to the ABC transporter superfamily
FY141_22180	COG0747	negative chemotaxis
FY141_22190	COG1960	acyl-CoA dehydrogenase activity
FY141_22220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY141_22235	COG1959	2 iron, 2 sulfur cluster binding
FY141_22240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22250	COG1473	amidohydrolase
FY141_22260	COG1126	abc transporter atp-binding protein
FY141_22265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_22275	COG0583	DNA-binding transcription factor activity
FY141_22290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_22300	COG1522	sequence-specific DNA binding
FY141_22305	COG4172	Belongs to the ABC transporter superfamily
FY141_22310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_22345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_22350	COG1012	belongs to the aldehyde dehydrogenase family
FY141_22355	COG0473	3-isopropylmalate dehydrogenase activity
FY141_22360	COG1012	belongs to the aldehyde dehydrogenase family
FY141_22405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_22410	COG1120	ATPase activity
FY141_22420	COG2226	methyltransferase
FY141_22435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_22440	COG1120	ATPase activity
FY141_22445	COG1595	DNA-templated transcription, initiation
FY141_22465	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY141_22470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_22490	COG0673	inositol 2-dehydrogenase activity
FY141_22495	COG0673	inositol 2-dehydrogenase activity
FY141_22505	COG1175	transmembrane transport
FY141_22510	COG0395	ABC-type sugar transport system, permease component
FY141_22515	COG3842	ATPase activity
FY141_22525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY141_22530	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY141_22535	COG2197	response regulator
FY141_22540	COG0601	transmembrane transport
FY141_22545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_22565	COG0747	negative chemotaxis
FY141_22580	COG1446	asparaginase
FY141_22585	COG0583	DNA-binding transcription factor activity
FY141_22590	COG0601	transmembrane transport
FY141_22595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_22610	COG0747	negative chemotaxis
FY141_22615	COG1473	amidohydrolase
FY141_22630	COG1129	ABC transporter
FY141_22635	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_22640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY141_22645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY141_22655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY141_22670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_22680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_22685	COG2079	MmgE PrpD family protein
FY141_22690	COG1126	abc transporter atp-binding protein
FY141_22695	COG0765	amino acid transport
FY141_22710	COG0281	malic enzyme
FY141_22710	COG0280	phosphate acetyltransferase
FY141_22715	COG0583	DNA-binding transcription factor activity
FY141_22740	COG1175	transmembrane transport
FY141_22745	COG0395	ABC-type sugar transport system, permease component
FY141_22760	COG0673	inositol 2-dehydrogenase activity
FY141_22765	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY141_22770	COG0720	synthase
FY141_22775	COG0602	queuosine metabolic process
FY141_22780	COG0673	inositol 2-dehydrogenase activity
FY141_22790	COG3842	ATPase activity
FY141_22805	COG1653	transport
FY141_22810	COG1609	Transcriptional regulator
FY141_22825	COG2094	Belongs to the DNA glycosylase MPG family
FY141_22835	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_22845	COG1376	ErfK ybiS ycfS ynhG family protein
FY141_22850	COG0840	transmembrane signaling receptor activity
FY141_22855	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY141_22865	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY141_22870	COG1596	polysaccharide export
FY141_22875	COG3307	-O-antigen
FY141_22905	COG2197	response regulator
FY141_22915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY141_22940	COG2942	2-epimerase
FY141_22950	COG1215	transferase activity, transferring glycosyl groups
FY141_22970	COG1473	amidohydrolase
FY141_22980	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_22985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY141_22990	COG1301	dicarboxylic acid transport
FY141_22995	COG4191	Histidine kinase
FY141_23000	COG2204	response regulator
FY141_23015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_23020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY141_23025	COG1522	sequence-specific DNA binding
FY141_23030	COG0351	phosphomethylpyrimidine kinase
FY141_23035	COG0352	thiamine-phosphate diphosphorylase activity
FY141_23040	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY141_23045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY141_23050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_23060	COG1501	Belongs to the glycosyl hydrolase 31 family
FY141_23065	COG0395	ABC-type sugar transport system, permease component
FY141_23070	COG1175	transmembrane transport
FY141_23075	COG1653	transport
FY141_23080	COG3842	ATPase activity
FY141_23085	COG2188	Transcriptional regulator
FY141_23095	COG4989	oxidoreductase activity
FY141_23130	COG0438	transferase activity, transferring glycosyl groups
FY141_23135	COG0747	negative chemotaxis
FY141_23140	COG0601	transmembrane transport
FY141_23150	COG3964	amidohydrolase
FY141_23165	COG1921	L-seryl-tRNASec selenium transferase activity
FY141_23170	COG4172	Belongs to the ABC transporter superfamily
FY141_23175	COG0625	glutathione transferase activity
FY141_23190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_23195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY141_23195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY141_23200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY141_23220	COG1312	Catalyzes the dehydration of D-mannonate
FY141_23225	COG1063	alcohol dehydrogenase
FY141_23230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY141_23240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY141_23245	COG2186	Transcriptional regulator
FY141_23250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY141_23255	COG0850	regulation of cytokinetic process
FY141_23260	COG2894	cell division
FY141_23265	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY141_23270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_23280	COG5001	Diguanylate cyclase
FY141_23295	COG0673	inositol 2-dehydrogenase activity
FY141_23305	COG1653	transport
FY141_23310	COG1175	transmembrane transport
FY141_23315	COG0395	ABC-type sugar transport system, permease component
FY141_23320	COG3842	ATPase activity
FY141_23330	COG0673	inositol 2-dehydrogenase activity
FY141_23360	COG0587	DNA-directed DNA polymerase activity
FY141_23365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY141_23380	COG2186	Transcriptional regulator
FY141_23385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_23390	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_23395	COG1129	ABC transporter
FY141_23400	COG1879	ABC-type sugar transport system periplasmic component
FY141_23405	COG0129	dihydroxy-acid dehydratase activity
FY141_23415	COG0346	lactoylglutathione lyase activity
FY141_23430	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY141_23435	COG4608	Belongs to the ABC transporter superfamily
FY141_23445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_23450	COG0601	transmembrane transport
FY141_23455	COG0747	negative chemotaxis
FY141_23465	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY141_23470	COG5001	Diguanylate cyclase
FY141_23480	COG3257	ureidoglycine aminohydrolase activity
FY141_23490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_23495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY141_23505	COG1129	ABC transporter
FY141_23510	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_23515	COG1879	ABC-type sugar transport system periplasmic component
FY141_23520	COG0583	DNA-binding transcription factor activity
FY141_23545	COG3047	cAMP biosynthetic process
FY141_23555	COG3842	ATPase activity
FY141_23560	COG0395	ABC-type sugar transport system, permease component
FY141_23565	COG1175	transmembrane transport
FY141_23570	COG1653	transport
FY141_23575	COG0523	cobalamin synthesis protein
FY141_23590	COG0523	cobalamin synthesis protein
FY141_23595	COG1121	(ABC) transporter
FY141_23605	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY141_23610	COG0454	-acetyltransferase
FY141_23625	COG0626	cystathionine gamma-synthase activity
FY141_23630	COG2182	Extracellular solute-binding protein
FY141_23640	COG0395	ABC-type sugar transport system, permease component
FY141_23655	COG0395	ABC-type sugar transport system, permease component
FY141_23660	COG1175	transmembrane transport
FY141_23665	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY141_23670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY141_23680	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_23685	COG1063	alcohol dehydrogenase
FY141_23690	COG1609	Transcriptional regulator
FY141_23695	COG2223	nitrite transmembrane transporter activity
FY141_23700	COG4977	sequence-specific DNA binding
FY141_23730	COG0667	Aldo Keto reductase
FY141_23745	COG2186	Transcriptional regulator
FY141_23750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY141_23755	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY141_23760	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_23765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY141_23770	COG4948	Mandelate Racemase Muconate Lactonizing
FY141_23775	COG3618	amidohydrolase
FY141_23785	COG1175	transmembrane transport
FY141_23790	COG0395	ABC-type sugar transport system, permease component
FY141_23795	COG3842	ATPase activity
FY141_23810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY141_23815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY141_23835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY141_23845	COG1278	Cold shock
FY141_23850	COG0673	inositol 2-dehydrogenase activity
FY141_23865	COG0673	inositol 2-dehydrogenase activity
FY141_23870	COG1309	transcriptional regulator
FY141_23875	COG1653	transport
FY141_23880	COG1175	transmembrane transport
FY141_23885	COG0395	ABC-type sugar transport system, permease component
FY141_23890	COG3842	ATPase activity
FY141_23895	COG1082	Xylose isomerase domain protein TIM barrel
FY141_23910	COG1609	Transcriptional regulator
FY141_23940	COG1175	transmembrane transport
FY141_23945	COG0395	ABC-type sugar transport system, permease component
FY141_23950	COG1116	anion transmembrane transporter activity
FY141_23955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_23960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY141_23975	COG3842	ATPase activity
FY141_23980	COG0395	ABC-type sugar transport system, permease component
FY141_23990	COG1653	transport
FY141_24025	COG3842	ATPase activity
FY141_24035	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_24040	COG0395	ABC-type sugar transport system, permease component
FY141_24100	COG2233	PERMEase
FY141_24115	COG5002	protein histidine kinase activity
FY141_24120	COG0745	RESPONSE REGULATOR receiver
FY141_24125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY141_24130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY141_24135	COG0702	epimerase
FY141_24145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY141_24180	COG2235	arginine
FY141_24190	COG0628	permease
FY141_24215	COG1522	sequence-specific DNA binding
FY141_24235	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_24250	COG1414	Transcriptional regulator
FY141_24260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY141_24290	COG4566	intracellular signal transduction
FY141_24295	COG4566	intracellular signal transduction
FY141_24305	COG0243	molybdopterin cofactor binding
FY141_24310	COG0783	Belongs to the Dps family
FY141_24325	COG0596	Alpha beta hydrolase
FY141_24335	COG1764	response to oxidative stress
FY141_24350	COG0596	Alpha beta hydrolase
FY141_24385	COG4172	Belongs to the ABC transporter superfamily
FY141_24410	COG0601	transmembrane transport
FY141_24415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_24420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_24430	COG4106	trans-aconitate 2-methyltransferase activity
FY141_24435	COG0025	NhaP-type Na H and K H
FY141_24440	COG4302	ethanolamine ammonia-lyase activity
FY141_24465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY141_24470	COG1349	DNA-binding transcription factor activity
FY141_24475	COG4608	Belongs to the ABC transporter superfamily
FY141_24485	COG0601	transmembrane transport
FY141_24490	COG0747	negative chemotaxis
FY141_24495	COG1454	alcohol dehydrogenase
FY141_24500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY141_24505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY141_24510	COG0411	ABC transporter
FY141_24545	COG1278	Cold shock
FY141_24575	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY141_24585	COG1192	Involved in chromosome partitioning
FY141_24590	COG1475	DNA binding
FY141_24595	COG0640	Transcriptional regulator
FY141_24610	COG1126	abc transporter atp-binding protein
FY141_24615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY141_24620	COG1609	Transcriptional regulator
FY141_24655	COG3239	Fatty acid desaturase
FY141_24665	COG1278	Cold shock
FY141_24745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY141_24745	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY141_24780	COG4191	Histidine kinase
FY141_24785	COG1132	(ABC) transporter
FY141_24795	COG0640	Transcriptional regulator
FY141_24825	COG4977	sequence-specific DNA binding
FY141_24830	COG2211	Major facilitator Superfamily
FY141_24835	COG2807	transmembrane transport
FY141_24840	COG1846	Transcriptional regulator
FY141_24855	COG2814	Major facilitator Superfamily
FY141_24885	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY141_24900	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY141_24905	COG0583	DNA-binding transcription factor activity
FY141_24920	COG0071	Belongs to the small heat shock protein (HSP20) family
FY141_24965	COG3838	Conjugal transfer protein Trbc
FY141_24970	COG3702	type iv secretory pathway
FY141_24975	COG3451	type IV secretory pathway VirB4
FY141_24990	COG3704	protein secretion by the type IV secretion system
FY141_25000	COG3736	Type IV secretory pathway, component VirB8
FY141_25005	COG3504	Conjugal transfer protein
FY141_25010	COG2948	multi-organism process
FY141_25015	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY141_25115	COG3831	ATPase activity
FY141_25130	COG3505	Type IV secretory pathway VirD4
FY141_25155	COG0583	DNA-binding transcription factor activity
FY141_25195	COG0745	RESPONSE REGULATOR receiver
FY141_25235	COG3842	ATPase activity
FY141_25240	COG4208	sulfate ABC transporter
FY141_25245	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_25265	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY141_25270	COG1942	4-Oxalocrotonate Tautomerase
FY141_25280	COG3971	2-oxopent-4-enoate hydratase activity
FY141_25290	COG1414	Transcriptional regulator
FY141_25300	COG1137	ATPase activity
FY141_25315	COG4177	L-phenylalanine transmembrane transporter activity
FY141_25335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY141_25340	COG1175	transmembrane transport
FY141_25345	COG0395	ABC-type sugar transport system, permease component
FY141_25355	COG0366	Alpha amylase catalytic
FY141_25360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY141_25365	COG1082	Xylose isomerase domain protein TIM barrel
FY141_25370	COG3842	ATPase activity
FY141_25380	COG1940	carbohydrate kinase activity
FY141_25385	COG0395	ABC-type sugar transport system, permease component
FY141_25395	COG2182	Extracellular solute-binding protein
FY141_25400	COG0673	inositol 2-dehydrogenase activity
FY141_25430	COG1126	abc transporter atp-binding protein
FY141_25435	COG0765	amino acid transport
FY141_25440	COG0765	amino acid transport
FY141_25450	COG4608	Belongs to the ABC transporter superfamily
FY141_25460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_25475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY141_25480	COG0583	DNA-binding transcription factor activity
FY141_25485	COG2423	ornithine cyclodeaminase activity
FY141_25495	COG1957	nucleoside hydrolase
FY141_25515	COG1335	isochorismatase
FY141_25520	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_25565	COG0583	DNA-binding transcription factor activity
FY141_25570	COG1902	pentaerythritol trinitrate reductase activity
FY141_25575	COG0583	DNA-binding transcription factor activity
FY141_25580	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_25590	COG1335	isochorismatase
FY141_25595	COG0583	DNA-binding transcription factor activity
FY141_25605	COG1695	Transcriptional regulator
FY141_25685	COG2207	Transcriptional regulator
FY141_25730	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_25745	COG1802	Transcriptional regulator
FY141_25750	COG3485	protocatechuate 3,4-dioxygenase
FY141_25755	COG3971	2-oxopent-4-enoate hydratase activity
FY141_25770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY141_25775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY141_25790	COG1063	alcohol dehydrogenase
FY141_25800	COG1960	acyl-CoA dehydrogenase activity
FY141_25805	COG1024	Enoyl-CoA hydratase
FY141_25815	COG1012	belongs to the aldehyde dehydrogenase family
FY141_25820	COG0477	Major facilitator Superfamily
FY141_25835	COG3706	GGDEF domain
FY141_25855	COG1846	Transcriptional regulator
FY141_25895	COG1012	belongs to the aldehyde dehydrogenase family
FY141_25905	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY141_25915	COG3386	PFAM SMP-30 Gluconolaconase
FY141_25920	COG3622	Belongs to the hyi family
FY141_25925	COG2084	Dehydrogenase
FY141_25950	COG1940	carbohydrate kinase activity
FY141_25955	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_25965	COG1129	ABC transporter
FY141_25985	COG0583	DNA-binding transcription factor activity
FY141_25990	COG2271	Major facilitator Superfamily
FY141_26000	COG2272	Belongs to the type-B carboxylesterase lipase family
FY141_26020	COG1129	ABC transporter
FY141_26045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY141_26055	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY141_26090	COG0583	DNA-binding transcription factor activity
FY141_26095	COG1414	Transcriptional regulator
FY141_26105	COG4948	Mandelate Racemase Muconate Lactonizing
FY141_26115	COG3842	ATPase activity
FY141_26120	COG1175	transmembrane transport
FY141_26125	COG0395	ABC-type sugar transport system, permease component
FY141_26135	COG0477	Major facilitator Superfamily
FY141_26170	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY141_26190	COG0747	negative chemotaxis
FY141_26200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_26215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_26225	COG4215	(ABC) transporter
FY141_26280	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY141_26285	COG0251	oxidation-reduction process
FY141_26290	COG3547	Transposase (IS116 IS110 IS902 family)
FY141_26325	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_26330	COG1335	isochorismatase
FY141_26340	COG1309	transcriptional regulator
FY141_26345	COG4604	ABC transporter, ATP-binding protein
FY141_26350	COG4605	iron ion homeostasis
FY141_26355	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY141_26365	COG2132	Multicopper oxidase
FY141_26370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY141_26375	COG4771	TonB-dependent receptor
FY141_26410	COG1695	Transcriptional regulator
FY141_26445	COG2132	Multicopper oxidase
FY141_26480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY141_26500	COG1192	Involved in chromosome partitioning
FY141_26505	COG1475	DNA binding
FY141_26510	COG0640	Transcriptional regulator
FY141_26515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY141_26560	COG0583	DNA-binding transcription factor activity
FY141_26570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY141_26575	COG1116	anion transmembrane transporter activity
FY141_26580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY141_26590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_26595	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_26625	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY141_26630	COG1129	ABC transporter
FY141_26655	COG4172	Belongs to the ABC transporter superfamily
FY141_26660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_26665	COG0601	transmembrane transport
FY141_26675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_26680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY141_26685	COG0583	DNA-binding transcription factor activity
FY141_26695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY141_26710	COG1132	(ABC) transporter
FY141_26715	COG4172	Belongs to the ABC transporter superfamily
FY141_26720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_26740	COG1082	Xylose isomerase domain protein TIM barrel
FY141_26745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY141_26750	COG0019	diaminopimelate decarboxylase activity
FY141_26760	COG1475	DNA binding
FY141_26770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY141_26865	COG1475	DNA binding
FY141_26890	COG2824	Alkylphosphonate utilization operon protein PhnA
FY141_26940	COG5489	Protein of unknown function (DUF736)
FY141_27025	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY141_27040	COG0747	negative chemotaxis
FY141_27045	COG0444	Belongs to the ABC transporter superfamily
FY141_27060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_27065	COG0584	glycerophosphoryl diester phosphodiesterase
FY141_27070	COG0483	inositol monophosphate 1-phosphatase activity
FY141_27135	COG3161	chorismate lyase activity
FY141_27285	COG3436	PFAM IS66 Orf2 family protein
FY141_27365	COG2222	sugar isomerase
FY141_27375	COG0006	proline dipeptidase activity
FY141_27395	COG1177	transmembrane transport
FY141_27400	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY141_27405	COG3842	ATPase activity
FY141_27435	COG3842	ATPase activity
FY141_27440	COG0006	proline dipeptidase activity
FY141_27460	COG0300	oxidoreductase activity
FY141_27465	COG0129	dihydroxy-acid dehydratase activity
FY141_27470	COG0667	Aldo Keto reductase
FY141_27480	COG1028	Short-chain dehydrogenase reductase Sdr
FY141_27490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_27495	COG0601	transmembrane transport
FY141_27500	COG4172	Belongs to the ABC transporter superfamily
FY141_27510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY141_27545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY141_27580	COG3701	Conjugal transfer protein
FY141_27585	COG3846	protein secretion by the type IV secretion system
FY141_27595	COG5314	conjugation
FY141_27600	COG3451	type IV secretory pathway VirB4
FY141_27615	COG4962	Type ii secretion system protein e