locus-tag	class	description
FY142_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY142_00010	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY142_00015	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY142_00020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FY142_00025	COG1420	regulation of RNA biosynthetic process
FY142_00030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY142_00035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY142_00040	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FY142_00050	COG1137	ATPase activity
FY142_00055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FY142_00065	COG0616	signal peptide processing
FY142_00070	COG0776	regulation of translation
FY142_00080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY142_00085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY142_00090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY142_00105	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY142_00110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FY142_00115	COG0728	peptidoglycan biosynthetic process
FY142_00125	COG0180	Tryptophanyl-tRNA synthetase
FY142_00135	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FY142_00140	COG1214	PFAM Peptidase M22, glycoprotease
FY142_00160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY142_00165	COG1702	phosphate starvation-inducible protein PhoH
FY142_00170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY142_00180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FY142_00185	COG1396	sequence-specific DNA binding
FY142_00190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY142_00195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY142_00200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_00210	COG0242	peptide deformylase activity
FY142_00215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY142_00220	COG0101	tRNA pseudouridine synthase activity
FY142_00230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_00235	COG2171	N-acyltransferase activity
FY142_00245	COG0840	transmembrane signaling receptor activity
FY142_00250	COG1957	nucleoside hydrolase
FY142_00255	COG0071	Belongs to the small heat shock protein (HSP20) family
FY142_00280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY142_00290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY142_00295	COG0706	membrane insertase activity
FY142_00300	COG0594	ribonuclease P activity
FY142_00305	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY142_00310	COG0840	transmembrane signaling receptor activity
FY142_00325	COG2226	methyltransferase
FY142_00330	COG3842	ATPase activity
FY142_00335	COG1175	transmembrane transport
FY142_00340	COG0395	ABC-type sugar transport system, permease component
FY142_00355	COG0427	acetyl-CoA hydrolase
FY142_00365	COG3938	Belongs to the proline racemase family
FY142_00370	COG0418	dihydroorotase activity
FY142_00375	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY142_00395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY142_00400	COG0166	Belongs to the GPI family
FY142_00405	COG0318	PFAM AMP-dependent synthetase and ligase
FY142_00410	COG3842	ATPase activity
FY142_00415	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_00420	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY142_00425	COG4774	siderophore transport
FY142_00470	COG2326	polyphosphate kinase activity
FY142_00475	COG5002	protein histidine kinase activity
FY142_00480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FY142_00485	COG0573	inorganic phosphate transmembrane transporter activity
FY142_00495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY142_00500	COG0704	Plays a role in the regulation of phosphate uptake
FY142_00505	COG0745	RESPONSE REGULATOR receiver
FY142_00515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY142_00520	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY142_00530	COG2967	ApaG domain
FY142_00545	COG0717	Belongs to the dCTP deaminase family
FY142_00555	COG0582	viral genome integration into host DNA
FY142_00580	COG0419	ATPase involved in DNA repair
FY142_00600	COG1396	sequence-specific DNA binding
FY142_00640	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FY142_00645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY142_00695	COG0167	dihydroorotate dehydrogenase activity
FY142_00730	COG1959	2 iron, 2 sulfur cluster binding
FY142_00735	COG1201	RNA secondary structure unwinding
FY142_00765	COG1960	acyl-CoA dehydrogenase activity
FY142_00770	COG0183	Belongs to the thiolase family
FY142_00775	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY142_00775	COG1024	Enoyl-CoA hydratase
FY142_00800	COG1320	monovalent cation:proton antiporter activity
FY142_00805	COG2212	antiporter activity
FY142_00810	COG1863	multisubunit Na H antiporter MnhE subunit
FY142_00815	COG0651	ATP synthesis coupled electron transport
FY142_00820	COG1006	Multisubunit Na H antiporter MnhC subunit
FY142_00825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY142_00825	COG2111	Na H antiporter
FY142_00835	COG0840	transmembrane signaling receptor activity
FY142_00845	COG0745	RESPONSE REGULATOR receiver
FY142_00850	COG2198	Histidine kinase
FY142_00850	COG0643	Histidine kinase
FY142_00855	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FY142_00860	COG2201	protein-glutamate methylesterase activity
FY142_00865	COG0745	RESPONSE REGULATOR receiver
FY142_00870	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FY142_00880	COG1766	The M ring may be actively involved in energy transduction
FY142_00885	COG2771	luxR family
FY142_00895	COG0840	transmembrane signaling receptor activity
FY142_00895	COG2972	Histidine kinase
FY142_00900	COG0784	Response regulator, receiver
FY142_00900	COG2198	Histidine kinase
FY142_00900	COG2205	protein histidine kinase activity
FY142_00905	COG1970	mechanosensitive ion channel activity
FY142_00910	COG0436	Aminotransferase
FY142_00925	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FY142_00930	COG0424	maF-like protein
FY142_00935	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY142_00945	COG5328	Belongs to the UPF0262 family
FY142_00950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY142_00960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY142_00980	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FY142_00990	COG1338	Plays a role in the flagellum-specific transport system
FY142_01000	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FY142_01010	COG1706	bacterial-type flagellum-dependent cell motility
FY142_01015	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FY142_01020	COG4786	Flagellar basal body rod
FY142_01025	COG1677	Flagellar hook-basal body complex protein FliE
FY142_01030	COG1558	bacterial-type flagellum-dependent cell motility
FY142_01035	COG1815	bacterial-type flagellum-dependent cell motility
FY142_01045	COG1157	protein secretion by the type III secretion system
FY142_01050	COG4786	Flagellar basal body rod
FY142_01060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FY142_01065	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY142_01070	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY142_01075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FY142_01080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY142_01100	COG1360	Flagellar Motor Protein
FY142_01145	COG5443	negative regulation of bacterial-type flagellum assembly
FY142_01150	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FY142_01160	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FY142_01200	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY142_01205	COG1609	Transcriptional regulator
FY142_01210	COG1653	transport
FY142_01215	COG1175	transmembrane transport
FY142_01220	COG0395	ABC-type sugar transport system, permease component
FY142_01225	COG0366	Alpha amylase catalytic
FY142_01230	COG3842	ATPase activity
FY142_01245	COG0129	dihydroxy-acid dehydratase activity
FY142_01250	COG0363	glucosamine-6-phosphate deaminase activity
FY142_01255	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FY142_01260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_01270	COG2081	HI0933 family
FY142_01290	COG2224	Isocitrate lyase
FY142_01305	COG3842	ATPase activity
FY142_01310	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_01315	COG1177	transmembrane transport
FY142_01330	COG2205	protein histidine kinase activity
FY142_01340	COG0248	Ppx GppA phosphatase
FY142_01345	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FY142_01350	COG0477	Major facilitator Superfamily
FY142_01380	COG0521	Mo-molybdopterin cofactor biosynthetic process
FY142_01385	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY142_01395	COG0142	geranyltranstransferase activity
FY142_01420	COG0752	glycyl-tRNA synthetase alpha subunit
FY142_01430	COG1704	LemA family
FY142_01435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY142_01445	COG0751	glycine-tRNA ligase activity
FY142_01450	COG1683	Conserved Protein
FY142_01455	COG0840	transmembrane signaling receptor activity
FY142_01465	COG0151	Belongs to the GarS family
FY142_01470	COG2183	response to ionizing radiation
FY142_01475	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY142_01500	COG0583	DNA-binding transcription factor activity
FY142_01520	COG0306	phosphate transporter
FY142_01530	COG0561	phosphatase activity
FY142_01535	COG0438	transferase activity, transferring glycosyl groups
FY142_01540	COG2186	Transcriptional regulator
FY142_01550	COG0583	DNA-binding transcription factor activity
FY142_01555	COG0277	FAD linked oxidase domain protein
FY142_01560	COG0277	FAD linked oxidase domain protein
FY142_01565	COG0247	lactate metabolic process
FY142_01575	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_01580	COG2818	Glycosylase
FY142_01590	COG2855	membrane
FY142_01595	COG0583	DNA-binding transcription factor activity
FY142_01625	COG0124	histidyl-tRNA synthetase
FY142_01635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY142_01640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY142_01645	COG2259	Doxx family
FY142_01655	COG0459	protein refolding
FY142_01660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY142_01670	COG0196	riboflavin kinase activity
FY142_01675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY142_01685	COG0590	tRNA wobble adenosine to inosine editing
FY142_01690	COG1187	pseudouridine synthase activity
FY142_01695	COG0742	ribosomal rna small subunit methyltransferase
FY142_01700	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY142_01710	COG0312	modulator of DNA gyrase
FY142_01715	COG0483	inositol monophosphate 1-phosphatase activity
FY142_01725	COG1519	Transferase
FY142_01735	COG1663	tetraacyldisaccharide 4'-kinase activity
FY142_01745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY142_01750	COG0745	RESPONSE REGULATOR receiver
FY142_01755	COG5001	Diguanylate cyclase
FY142_01755	COG3300	MHYT domain
FY142_01760	COG3386	PFAM SMP-30 Gluconolaconase
FY142_01765	COG0800	Aldolase
FY142_01770	COG3734	2-keto-3-deoxy-galactonokinase
FY142_01775	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_01780	COG1414	Transcriptional regulator
FY142_01785	COG2197	response regulator
FY142_01800	COG0598	Magnesium transport protein CorA
FY142_01805	COG3158	transport of potassium into the cell
FY142_01820	COG0356	it plays a direct role in the translocation of protons across the membrane
FY142_01830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY142_01835	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY142_01850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY142_01870	COG0009	L-threonylcarbamoyladenylate synthase
FY142_01880	COG4638	Rieske (2fe-2S)
FY142_01905	COG1960	acyl-CoA dehydrogenase activity
FY142_01920	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY142_01925	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY142_01930	COG0840	transmembrane signaling receptor activity
FY142_01940	COG1522	sequence-specific DNA binding
FY142_01965	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FY142_01970	COG1741	Belongs to the pirin family
FY142_01975	COG1722	exodeoxyribonuclease VII activity
FY142_01980	COG0123	including yeast histone deacetylase and acetoin utilization protein
FY142_01985	COG1268	BioY protein
FY142_01990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY142_01995	COG1122	ATPase activity
FY142_02000	COG3214	Protein conserved in bacteria
FY142_02005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY142_02005	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY142_02010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY142_02030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY142_02045	COG0259	pyridoxamine-phosphate oxidase activity
FY142_02075	COG0312	modulator of DNA gyrase
FY142_02090	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY142_02095	COG0109	protoheme IX farnesyltransferase activity
FY142_02100	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FY142_02115	COG3346	SURF1 family
FY142_02120	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FY142_02125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FY142_02130	COG0328	RNA-DNA hybrid ribonuclease activity
FY142_02140	COG0678	peroxiredoxin activity
FY142_02140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY142_02150	COG1678	Uncharacterized ACR, COG1678
FY142_02155	COG3237	CsbD-like
FY142_02165	COG5001	Diguanylate cyclase
FY142_02165	COG3300	MHYT domain
FY142_02170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY142_02175	COG0612	Peptidase, M16
FY142_02200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY142_02205	COG1802	Transcriptional regulator
FY142_02220	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FY142_02225	COG3609	addiction module antidote protein, CC2985 family
FY142_02230	COG3668	Plasmid stabilization system
FY142_02240	COG1194	a g-specific adenine glycosylase
FY142_02255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FY142_02260	COG1196	nuclear chromosome segregation
FY142_02265	COG2514	catechol 2,3-dioxygenase activity
FY142_02270	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY142_02270	COG0574	Belongs to the PEP-utilizing enzyme family
FY142_02280	COG1823	symporter activity
FY142_02305	COG0579	oxidoreductase
FY142_02320	COG2895	sulfate adenylyltransferase (ATP) activity
FY142_02325	COG0175	sulfate reduction
FY142_02330	COG0175	sulfate reduction
FY142_02335	COG1959	2 iron, 2 sulfur cluster binding
FY142_02340	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FY142_02345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY142_02350	COG4208	sulfate ABC transporter
FY142_02355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY142_02365	COG2199	diguanylate cyclase activity
FY142_02365	COG2200	EAL domain
FY142_02365	COG2203	Gaf domain
FY142_02375	COG1309	transcriptional regulator
FY142_02380	COG1012	belongs to the aldehyde dehydrogenase family
FY142_02385	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FY142_02415	COG0625	glutathione transferase activity
FY142_02425	COG0477	Major facilitator Superfamily
FY142_02435	COG3657	addiction module killer protein
FY142_02445	COG1793	dna ligase
FY142_02465	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_02470	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_02475	COG1846	Transcriptional regulator
FY142_02480	COG1764	response to oxidative stress
FY142_02495	COG0488	(ABC) transporter
FY142_02530	COG4221	oxidoreductase activity
FY142_02545	COG0433	COG0433 Predicted ATPase
FY142_02555	COG1733	regulation of RNA biosynthetic process
FY142_02560	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
FY142_02575	COG0656	L-ascorbic acid biosynthetic process
FY142_02580	COG3781	membrane
FY142_02585	COG2378	regulation of single-species biofilm formation
FY142_02595	COG4106	trans-aconitate 2-methyltransferase activity
FY142_02600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY142_02605	COG0840	transmembrane signaling receptor activity
FY142_02610	COG0583	DNA-binding transcription factor activity
FY142_02625	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY142_02645	COG3909	cytochrome
FY142_02650	COG2010	Cytochrome c
FY142_02685	COG0789	Transcriptional regulator
FY142_02710	COG0517	IMP dehydrogenase activity
FY142_02710	COG4175	Glycine betaine
FY142_02715	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_02740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_02750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY142_02750	COG2169	Transcriptional regulator
FY142_02760	COG2514	catechol 2,3-dioxygenase activity
FY142_02780	COG1272	protein, Hemolysin III
FY142_02790	COG1280	lysine exporter protein (LysE YggA)
FY142_02795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY142_02800	COG2111	Na H antiporter
FY142_02800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FY142_02805	COG2111	Na H antiporter
FY142_02810	COG1006	Multisubunit Na H antiporter MnhC subunit
FY142_02815	COG0651	ATP synthesis coupled electron transport
FY142_02820	COG1863	multisubunit Na H antiporter MnhE subunit
FY142_02825	COG2212	antiporter activity
FY142_02830	COG1320	monovalent cation:proton antiporter activity
FY142_02835	COG4957	zinc ion binding
FY142_02850	COG2166	iron-sulfur cluster assembly
FY142_02860	COG2205	protein histidine kinase activity
FY142_02905	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY142_02910	COG2983	Belongs to the UPF0260 family
FY142_02925	COG2217	Heavy metal translocating P-type atpase
FY142_02955	COG2814	Major facilitator Superfamily
FY142_02960	COG1621	beta-fructofuranosidase activity
FY142_02965	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FY142_03015	COG4695	Portal protein
FY142_03120	COG4235	cytochrome complex assembly
FY142_03125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FY142_03130	COG1138	Cytochrome C-type biogenesis protein
FY142_03135	COG3088	subunit of a heme lyase
FY142_03140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY142_03145	COG0745	RESPONSE REGULATOR receiver
FY142_03150	COG2205	protein histidine kinase activity
FY142_03155	COG3011	Protein conserved in bacteria
FY142_03160	COG3713	MltA-interacting MipA family protein
FY142_03165	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FY142_03170	COG2202	Pas domain
FY142_03170	COG2205	protein histidine kinase activity
FY142_03180	COG0308	aminopeptidase N
FY142_03185	COG0697	spore germination
FY142_03200	COG0443	Heat shock 70 kDa protein
FY142_03235	COG0604	alcohol dehydrogenase
FY142_03240	COG1733	regulation of RNA biosynthetic process
FY142_03245	COG1968	undecaprenyl-diphosphatase activity
FY142_03250	COG2239	Acts as a magnesium transporter
FY142_03255	COG2814	Major facilitator Superfamily
FY142_03280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY142_03305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY142_03345	COG0741	lytic transglycosylase activity
FY142_03350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_03355	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY142_03360	COG0840	transmembrane signaling receptor activity
FY142_03370	COG1758	RNA polymerase activity
FY142_03390	COG0736	holo-[acyl-carrier-protein] synthase activity
FY142_03395	COG0681	Belongs to the peptidase S26 family
FY142_03400	COG0571	ribonuclease III activity
FY142_03405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FY142_03415	COG0784	Response regulator, receiver
FY142_03420	COG1381	Involved in DNA repair and RecF pathway recombination
FY142_03430	COG2226	methyltransferase
FY142_03440	COG1418	mRNA catabolic process
FY142_03450	COG0346	lactoylglutathione lyase activity
FY142_03465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_03470	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY142_03475	COG0668	transmembrane transport
FY142_03485	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FY142_03515	COG1742	UPF0060 membrane protein
FY142_03530	COG1183	phosphatidylcholine synthase activity
FY142_03535	COG0688	phosphatidylethanolamine metabolic process
FY142_03540	COG5265	(ABC) transporter
FY142_03580	COG2852	Protein conserved in bacteria
FY142_03585	COG0215	cysteine-tRNA ligase activity
FY142_03590	COG4221	oxidoreductase activity
FY142_03595	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FY142_03600	COG1286	toxin biosynthetic process
FY142_03615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY142_03625	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY142_03635	COG0305	Participates in initiation and elongation during chromosome replication
FY142_03655	COG0359	binds to the 23S rRNA
FY142_03665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY142_03670	COG0360	Binds together with S18 to 16S ribosomal RNA
FY142_03680	COG0667	Aldo Keto reductase
FY142_03685	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY142_03695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_03700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY142_03710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY142_03715	COG1561	YicC-like family, N-terminal region
FY142_03720	COG0194	GDP metabolic process
FY142_03735	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY142_03740	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY142_03750	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FY142_03765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY142_03785	COG3706	GGDEF domain
FY142_03785	COG4251	negative regulation of phosphorylation
FY142_03785	COG5001	Diguanylate cyclase
FY142_03785	COG2203	Gaf domain
FY142_03790	COG3300	MHYT domain
FY142_03790	COG5001	Diguanylate cyclase
FY142_03795	COG4191	Histidine kinase
FY142_03800	COG4566	intracellular signal transduction
FY142_03810	COG0488	(ABC) transporter
FY142_03815	COG3706	GGDEF domain
FY142_03825	COG0105	UTP biosynthetic process
FY142_03845	COG0314	molybdopterin synthase activity
FY142_03855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY142_03860	COG0322	excinuclease ABC activity
FY142_03865	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_03890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FY142_03895	COG0243	molybdopterin cofactor binding
FY142_03910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY142_03915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY142_03920	COG2226	methyltransferase
FY142_03925	COG0628	permease
FY142_03935	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FY142_03940	COG0248	Ppx GppA phosphatase
FY142_03965	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
FY142_03975	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FY142_03980	COG0477	Major facilitator Superfamily
FY142_03985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY142_03995	COG0840	transmembrane signaling receptor activity
FY142_04000	COG0659	secondary active sulfate transmembrane transporter activity
FY142_04010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY142_04015	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FY142_04025	COG0113	porphobilinogen synthase activity
FY142_04045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY142_04050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY142_04055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY142_04055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY142_04065	COG1280	lysine exporter protein (LysE YggA)
FY142_04070	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY142_04075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY142_04080	COG2814	Major facilitator Superfamily
FY142_04085	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FY142_04105	COG0416	fatty acid biosynthetic process
FY142_04110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY142_04115	COG0776	regulation of translation
FY142_04150	COG0601	transmembrane transport
FY142_04155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_04160	COG0444	Belongs to the ABC transporter superfamily
FY142_04170	COG0747	negative chemotaxis
FY142_04180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY142_04185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY142_04200	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY142_04205	COG0583	DNA-binding transcription factor activity
FY142_04210	COG0737	Belongs to the 5'-nucleotidase family
FY142_04230	COG2897	thiosulfate sulfurtransferase activity
FY142_04245	COG0415	Belongs to the DNA photolyase family
FY142_04255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY142_04285	COG3932	Exopolysaccharide synthesis, ExoD
FY142_04290	COG1238	metal cluster binding
FY142_04365	COG1612	heme a metabolic process
FY142_04375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY142_04380	COG0010	Belongs to the arginase family
FY142_04385	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FY142_04390	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY142_04400	COG1832	CoA-binding protein
FY142_04430	COG2124	cytochrome p450
FY142_04435	COG2199	diguanylate cyclase activity
FY142_04440	COG0740	serine-type endopeptidase activity
FY142_04445	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY142_04450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FY142_04460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY142_04485	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_04490	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_04495	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_04505	COG0649	NAD binding
FY142_04515	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FY142_04520	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FY142_04530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FY142_04535	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FY142_04545	COG0713	ATP synthesis coupled electron transport
FY142_04560	COG1007	ATP synthesis coupled electron transport
FY142_04565	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY142_04565	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY142_04580	COG0442	prolyl-tRNA aminoacylation
FY142_04590	COG1136	(ABC) transporter
FY142_04605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY142_04625	COG0784	Response regulator, receiver
FY142_04635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY142_04640	COG0477	Major facilitator Superfamily
FY142_04655	COG0557	exoribonuclease II activity
FY142_04660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY142_04670	COG0758	DNA mediated transformation
FY142_04675	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY142_04685	COG0540	Belongs to the ATCase OTCase family
FY142_04700	COG1960	acyl-CoA dehydrogenase activity
FY142_04705	COG0456	acetyltransferase
FY142_04720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY142_04725	COG2824	Alkylphosphonate utilization operon protein PhnA
FY142_04730	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FY142_04735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY142_04740	COG0154	amidase activity
FY142_04745	COG0456	acetyltransferase
FY142_04750	COG3811	Belongs to the UPF0386 family
FY142_04765	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY142_04795	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FY142_04800	COG0439	Biotin carboxylase
FY142_04805	COG0511	ligase activity, forming carbon-carbon bonds
FY142_04810	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY142_04820	COG0436	Aminotransferase
FY142_04840	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_04845	COG1530	ribonuclease E activity
FY142_04855	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY142_04875	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY142_04880	COG0384	phenazine biosynthesis protein PhzF
FY142_04900	COG0633	Ferredoxin
FY142_04915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FY142_04920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FY142_04930	COG3768	UPF0283 membrane protein
FY142_04935	COG3106	COG3106 Predicted ATPase
FY142_04965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY142_05000	COG0537	adenosine 5'-monophosphoramidase activity
FY142_05025	COG0052	Belongs to the universal ribosomal protein uS2 family
FY142_05030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY142_05035	COG0528	UMP kinase activity
FY142_05040	COG0233	cytoplasmic translational termination
FY142_05045	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY142_05055	COG0750	zinc metalloprotease
FY142_05060	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY142_05065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY142_05070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY142_05075	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY142_05080	COG3494	Protein of unknown function (DUF1009)
FY142_05085	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FY142_05090	COG2186	Transcriptional regulator
FY142_05100	COG0765	amino acid transport
FY142_05105	COG0765	amino acid transport
FY142_05115	COG0372	Belongs to the citrate synthase family
FY142_05130	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY142_05155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY142_05160	COG1459	type II secretion system
FY142_05215	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FY142_05220	COG0148	phosphopyruvate hydratase activity
FY142_05230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY142_05235	COG0022	dehydrogenase e1 component
FY142_05235	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY142_05240	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY142_05250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY142_05260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FY142_05265	COG0697	spore germination
FY142_05280	COG2867	negative regulation of translational initiation
FY142_05285	COG1546	Belongs to the CinA family
FY142_05290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FY142_05290	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FY142_05300	COG3852	Histidine kinase
FY142_05305	COG2204	response regulator
FY142_05310	COG5000	phosphorelay sensor kinase activity
FY142_05315	COG2204	response regulator
FY142_05320	COG0569	domain protein
FY142_05325	COG1923	regulation of RNA biosynthetic process
FY142_05330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY142_05335	COG3956	TIGRFAM MazG family protein
FY142_05345	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY142_05345	COG1648	precorrin-2 dehydrogenase activity
FY142_05385	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY142_05385	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FY142_05390	COG0509	glycine decarboxylation via glycine cleavage system
FY142_05395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_05420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FY142_05425	COG0564	pseudouridine synthase activity
FY142_05445	COG0251	oxidation-reduction process
FY142_05450	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FY142_05460	COG1671	Belongs to the UPF0178 family
FY142_05475	COG0450	alkyl hydroperoxide reductase
FY142_05480	COG0625	glutathione transferase activity
FY142_05490	COG2801	Transposase and inactivated derivatives
FY142_05495	COG0431	NADPH-dependent FMN reductase
FY142_05505	COG0798	PFAM Bile acid sodium symporter
FY142_05510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY142_05525	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY142_05525	COG0321	lipoyl(octanoyl) transferase activity
FY142_05530	COG0084	hydrolase, TatD family'
FY142_05535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY142_05545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY142_05595	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FY142_05600	COG2095	MarC family integral membrane protein
FY142_05605	COG0617	tRNA 3'-terminal CCA addition
FY142_05605	COG0517	IMP dehydrogenase activity
FY142_05605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY142_05615	COG0629	single-stranded DNA binding
FY142_05620	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY142_05630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY142_05650	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY142_05655	COG1121	(ABC) transporter
FY142_05675	COG0667	Aldo Keto reductase
FY142_05685	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FY142_05770	COG2239	Acts as a magnesium transporter
FY142_05775	COG0243	molybdopterin cofactor binding
FY142_05785	COG0242	peptide deformylase activity
FY142_05795	COG2205	protein histidine kinase activity
FY142_05795	COG2202	Pas domain
FY142_05805	COG0321	lipoyl(octanoyl) transferase activity
FY142_05810	COG1064	alcohol dehydrogenase
FY142_05840	COG1862	Preprotein translocase
FY142_05860	COG2124	cytochrome p450
FY142_05875	COG0596	Alpha beta hydrolase
FY142_05885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_05890	COG0626	cystathionine gamma-synthase activity
FY142_05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_05900	COG4597	amino acid ABC transporter
FY142_05905	COG0765	amino acid transport
FY142_05910	COG1126	abc transporter atp-binding protein
FY142_05925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY142_05940	COG0436	Aminotransferase
FY142_05970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY142_05980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY142_05985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_05990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY142_06005	COG3243	poly(R)-hydroxyalkanoic acid synthase
FY142_06010	COG1489	DNA binding
FY142_06015	COG0024	Methionine aminopeptidase
FY142_06020	COG2003	Belongs to the UPF0758 family
FY142_06035	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FY142_06060	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY142_06065	COG0546	phosphoglycolate phosphatase activity
FY142_06075	COG0114	fumarate hydratase activity
FY142_06085	COG0504	CTP synthase activity
FY142_06095	COG0149	triose-phosphate isomerase activity
FY142_06105	COG0187	DNA topoisomerase II activity
FY142_06115	COG0740	serine-type endopeptidase activity
FY142_06125	COG0640	Transcriptional regulator
FY142_06130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY142_06135	COG0745	RESPONSE REGULATOR receiver
FY142_06150	COG3264	Mechanosensitive ion channel
FY142_06150	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FY142_06215	COG1127	ABC transporter
FY142_06220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FY142_06225	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_06235	COG0280	phosphate acetyltransferase
FY142_06235	COG0281	malic enzyme
FY142_06245	COG0778	Nitroreductase
FY142_06250	COG0823	Involved in the tonB-independent uptake of proteins
FY142_06265	COG1368	sulfuric ester hydrolase activity
FY142_06290	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY142_06310	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY142_06330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FY142_06345	COG0318	PFAM AMP-dependent synthetase and ligase
FY142_06355	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY142_06355	COG0512	Glutamine amidotransferase of anthranilate synthase
FY142_06360	COG0343	queuine tRNA-ribosyltransferase activity
FY142_06365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY142_06380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY142_06395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY142_06400	COG0134	indole-3-glycerol-phosphate synthase activity
FY142_06405	COG0315	cyclic pyranopterin monophosphate synthase activity
FY142_06410	COG0303	'Molybdopterin
FY142_06415	COG3706	GGDEF domain
FY142_06425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FY142_06425	COG0475	glutathione-regulated potassium exporter activity
FY142_06435	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FY142_06445	COG2814	Major facilitator Superfamily
FY142_06450	COG0746	molybdenum cofactor guanylyltransferase activity
FY142_06455	COG1763	Mo-molybdopterin cofactor biosynthetic process
FY142_06460	COG0739	heme binding
FY142_06465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY142_06470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FY142_06475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY142_06480	COG0805	protein transport
FY142_06485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY142_06490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FY142_06495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY142_06500	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY142_06505	COG1472	Belongs to the glycosyl hydrolase 3 family
FY142_06515	COG0018	arginyl-trna synthetase
FY142_06520	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FY142_06545	COG0525	valine-tRNA ligase activity
FY142_06555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FY142_06695	COG1525	nuclease
FY142_06770	COG3567	Phage-associated protein, HI1409 family
FY142_06820	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY142_07010	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY142_07015	COG1058	Belongs to the CinA family
FY142_07015	COG1546	Belongs to the CinA family
FY142_07020	COG0589	response to stress
FY142_07025	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FY142_07035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY142_07045	COG0640	Transcriptional regulator
FY142_07050	COG1914	H( )-stimulated, divalent metal cation uptake system
FY142_07060	COG1132	(ABC) transporter
FY142_07065	COG0628	permease
FY142_07100	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FY142_07110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY142_07120	COG0302	gtp cyclohydrolase
FY142_07125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY142_07130	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY142_07140	COG0516	GMP reductase activity
FY142_07140	COG0517	IMP dehydrogenase activity
FY142_07175	COG1760	l-serine dehydratase
FY142_07215	COG0583	DNA-binding transcription factor activity
FY142_07230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY142_07230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FY142_07240	COG0347	Belongs to the P(II) protein family
FY142_07245	COG0174	glutamine synthetase
FY142_07275	COG0697	spore germination
FY142_07285	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY142_07295	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY142_07325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY142_07335	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FY142_07340	COG2186	Transcriptional regulator
FY142_07350	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY142_07355	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY142_07360	COG3845	ABC transporter
FY142_07365	COG1183	phosphatidylcholine synthase activity
FY142_07370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_07375	COG0679	Auxin Efflux Carrier
FY142_07380	COG0785	Cytochrome C biogenesis protein
FY142_07400	COG1278	Cold shock
FY142_07450	COG0577	efflux transmembrane transporter activity
FY142_07450	COG1136	(ABC) transporter
FY142_07455	COG0577	efflux transmembrane transporter activity
FY142_07455	COG1136	(ABC) transporter
FY142_07480	COG2151	metal-sulfur cluster biosynthetic enzyme
FY142_07485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY142_07490	COG0719	Fe-S assembly protein
FY142_07495	COG0396	ATPase activity
FY142_07500	COG0719	Fe-S assembly protein
FY142_07505	COG1104	cysteine desulfurase activity
FY142_07510	COG2945	thiolester hydrolase activity
FY142_07515	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FY142_07520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY142_07530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FY142_07535	COG2833	Protein of unknown function (DUF455)
FY142_07540	COG0739	heme binding
FY142_07545	COG0513	Belongs to the DEAD box helicase family
FY142_07570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY142_07580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY142_07585	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY142_07590	COG0047	phosphoribosylformylglycinamidine synthase activity
FY142_07605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_07610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY142_07630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FY142_07635	COG2814	Major facilitator Superfamily
FY142_07640	COG0483	inositol monophosphate 1-phosphatase activity
FY142_07645	COG0483	inositol monophosphate 1-phosphatase activity
FY142_07650	COG0037	tRNA processing
FY142_07655	COG2066	Belongs to the glutaminase family
FY142_07660	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY142_07665	COG0861	Integral membrane protein TerC family
FY142_07680	COG1280	lysine exporter protein (LysE YggA)
FY142_07690	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY142_07695	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FY142_07705	COG0538	isocitrate dehydrogenase activity
FY142_07715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY142_07720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY142_07725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_07730	COG2313	pseudouridylate synthase activity
FY142_07740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_07745	COG4215	(ABC) transporter
FY142_07755	COG5425	PFAM Usg family protein
FY142_07765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_07770	COG1522	sequence-specific DNA binding
FY142_07775	COG1573	uracil-dna glycosylase
FY142_07785	COG2205	protein histidine kinase activity
FY142_07785	COG2202	Pas domain
FY142_07790	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY142_07795	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FY142_07800	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FY142_07815	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY142_07820	COG0842	Transport permease protein
FY142_07825	COG1131	(ABC) transporter
FY142_07830	COG0730	response to heat
FY142_07830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY142_07850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY142_07855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY142_07875	COG0129	dihydroxy-acid dehydratase activity
FY142_07880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FY142_07885	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FY142_07895	COG3739	integral membrane protein
FY142_07900	COG0203	ribosomal protein L17
FY142_07905	COG0202	RNA polymerase activity
FY142_07910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FY142_07915	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY142_07920	COG0563	adenylate kinase activity
FY142_07925	COG0201	protein transport
FY142_07930	COG0200	Binds to the 23S rRNA
FY142_07935	COG1841	ribosomal large subunit assembly
FY142_07940	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY142_07945	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FY142_07950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY142_07955	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY142_07960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY142_07965	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY142_07970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FY142_07975	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY142_07980	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FY142_07985	COG0255	Belongs to the universal ribosomal protein uL29 family
FY142_07990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FY142_07995	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY142_08000	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FY142_08005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FY142_08010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY142_08015	COG0089	rRNA binding
FY142_08020	COG0088	Forms part of the polypeptide exit tunnel
FY142_08025	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY142_08030	COG0051	transcription antitermination factor activity, RNA binding
FY142_08035	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY142_08040	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY142_08045	COG0049	tRNA binding
FY142_08050	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY142_08070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY142_08075	COG0085	RNA polymerase activity
FY142_08080	COG0222	ribosome binding
FY142_08085	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY142_08090	COG0081	regulation of translation
FY142_08095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY142_08105	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FY142_08115	COG1086	Polysaccharide biosynthesis protein
FY142_08120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY142_08125	COG0861	Integral membrane protein TerC family
FY142_08130	COG3895	Periplasmic Protein
FY142_08150	COG1132	(ABC) transporter
FY142_08155	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY142_08175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FY142_08210	COG2205	protein histidine kinase activity
FY142_08210	COG2198	Histidine kinase
FY142_08210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_08210	COG0784	Response regulator, receiver
FY142_08215	COG0784	Response regulator, receiver
FY142_08220	COG2202	Pas domain
FY142_08220	COG3920	Histidine kinase
FY142_08225	COG0784	Response regulator, receiver
FY142_08230	COG4251	negative regulation of phosphorylation
FY142_08245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY142_08250	COG1607	acyl-coa hydrolase
FY142_08270	COG2910	NAD(P)H-binding
FY142_08275	COG1733	regulation of RNA biosynthetic process
FY142_08290	COG0556	nucleotide-excision repair
FY142_08300	COG2382	esterase
FY142_08320	COG0484	heat shock protein binding
FY142_08340	COG3706	GGDEF domain
FY142_08360	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_08365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_08380	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY142_08390	COG2207	Transcriptional regulator
FY142_08395	COG1064	alcohol dehydrogenase
FY142_08400	COG1252	NADH dehydrogenase
FY142_08405	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FY142_08410	COG2197	response regulator
FY142_08415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY142_08450	COG0656	L-ascorbic acid biosynthetic process
FY142_08465	COG0440	acetolactate synthase activity
FY142_08470	COG0028	Belongs to the TPP enzyme family
FY142_08480	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY142_08485	COG3830	Belongs to the UPF0237 family
FY142_08485	COG0560	Phosphoserine phosphatase
FY142_08505	COG0330	HflC and HflK could
FY142_08510	COG0330	HflC and HflK could
FY142_08520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY142_08555	COG0277	FAD linked oxidase domain protein
FY142_08560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_08600	COG1335	isochorismatase
FY142_08625	COG2264	protein methyltransferase activity
FY142_08630	COG1999	signal sequence binding
FY142_08640	COG0835	chemotaxis
FY142_08650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY142_08655	COG0583	DNA-binding transcription factor activity
FY142_08665	COG1247	-acetyltransferase
FY142_08675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY142_08680	COG0497	DNA recombination
FY142_08685	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FY142_08695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY142_08700	COG0849	cell division
FY142_08705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FY142_08710	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY142_08715	COG0477	Major facilitator Superfamily
FY142_08720	COG5001	Diguanylate cyclase
FY142_08725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY142_08730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY142_08735	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY142_08745	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY142_08750	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY142_08760	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY142_08775	COG0275	rRNA processing
FY142_08780	COG2001	Belongs to the MraZ family
FY142_08805	COG3023	N-Acetylmuramoyl-L-alanine amidase
FY142_08835	COG4106	trans-aconitate 2-methyltransferase activity
FY142_08855	COG2226	methyltransferase
FY142_08865	COG2267	carboxylic ester hydrolase activity
FY142_08870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FY142_08885	COG0251	oxidation-reduction process
FY142_08900	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_08905	COG2814	Major facilitator Superfamily
FY142_08935	COG1012	belongs to the aldehyde dehydrogenase family
FY142_08940	COG0174	glutamine synthetase
FY142_08945	COG0531	amino acid
FY142_08955	COG1737	Transcriptional regulator
FY142_08960	COG2182	Extracellular solute-binding protein
FY142_08975	COG3842	ATPase activity
FY142_09035	COG2968	Membrane
FY142_09045	COG0432	Pfam Uncharacterised protein family UPF0047
FY142_09060	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY142_09065	COG0358	DNA primase activity
FY142_09085	COG0505	Belongs to the CarA family
FY142_09090	COG0534	Mate efflux family protein
FY142_09105	COG2321	neutral zinc metallopeptidase
FY142_09120	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY142_09130	COG3706	GGDEF domain
FY142_09145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY142_09155	COG1522	sequence-specific DNA binding
FY142_09160	COG0492	ferredoxin-NADP+ reductase activity
FY142_09165	COG0583	DNA-binding transcription factor activity
FY142_09175	COG1902	pentaerythritol trinitrate reductase activity
FY142_09200	COG0387	Pfam Sodium calcium exchanger
FY142_09205	COG0436	Aminotransferase
FY142_09210	COG2199	diguanylate cyclase activity
FY142_09210	COG2200	EAL domain
FY142_09225	COG1278	Cold shock
FY142_09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY142_09240	COG1846	Transcriptional regulator
FY142_09245	COG0745	RESPONSE REGULATOR receiver
FY142_09255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY142_09275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY142_09285	COG1496	oxidoreductase activity
FY142_09300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY142_09310	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FY142_09325	COG0840	transmembrane signaling receptor activity
FY142_09330	COG1012	belongs to the aldehyde dehydrogenase family
FY142_09335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FY142_09340	COG3300	MHYT domain
FY142_09340	COG5001	Diguanylate cyclase
FY142_09345	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FY142_09350	COG5001	Diguanylate cyclase
FY142_09360	COG0193	aminoacyl-tRNA hydrolase activity
FY142_09370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FY142_09395	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY142_09405	COG2857	Cytochrome c1
FY142_09405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FY142_09425	COG1132	(ABC) transporter
FY142_09435	COG1132	(ABC) transporter
FY142_09445	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FY142_09460	COG0408	coproporphyrinogen oxidase activity
FY142_09475	COG0617	tRNA 3'-terminal CCA addition
FY142_09490	COG0714	Associated with various cellular activities
FY142_09510	COG0454	-acetyltransferase
FY142_09525	COG0477	Major facilitator Superfamily
FY142_09535	COG0435	Glutathione S-transferase
FY142_09540	COG0494	nUDIX hydrolase
FY142_09550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY142_09555	COG3135	benzoate transporter
FY142_09580	COG0740	serine-type endopeptidase activity
FY142_09595	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY142_09600	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY142_09625	COG4175	Glycine betaine
FY142_09645	COG1435	thymidine kinase activity
FY142_09670	COG1629	transport
FY142_09670	COG4771	TonB-dependent receptor
FY142_09680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY142_09680	COG0512	Glutamine amidotransferase of anthranilate synthase
FY142_09695	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY142_09705	COG0366	Alpha amylase catalytic
FY142_09710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_09730	COG1160	GTP binding
FY142_09750	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FY142_09760	COG0024	Methionine aminopeptidase
FY142_09770	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_09790	COG0583	DNA-binding transcription factor activity
FY142_09805	COG0402	S-adenosylhomocysteine deaminase activity
FY142_09815	COG1304	FMN binding
FY142_09825	COG1309	transcriptional regulator
FY142_09830	COG1686	Belongs to the peptidase S11 family
FY142_09840	COG2351	hydroxyisourate hydrolase activity
FY142_09845	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FY142_09870	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY142_09880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_09880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FY142_09890	COG0513	Belongs to the DEAD box helicase family
FY142_09900	COG2259	Doxx family
FY142_09905	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_09915	COG2308	Evidence 4 Homologs of previously reported genes of
FY142_09925	COG1305	Transglutaminase-like
FY142_09950	COG4214	carbohydrate transport
FY142_09960	COG4213	ABC transporter substrate-binding protein
FY142_10015	COG2948	multi-organism process
FY142_10025	COG3701	Conjugal transfer protein
FY142_10030	COG3846	protein secretion by the type IV secretion system
FY142_10045	COG3451	type IV secretory pathway VirB4
FY142_10060	COG4962	Type ii secretion system protein e
FY142_10085	COG0583	DNA-binding transcription factor activity
FY142_10095	COG1566	PFAM secretion protein HlyD family protein
FY142_10110	COG2207	Transcriptional regulator
FY142_10115	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_10125	COG0583	DNA-binding transcription factor activity
FY142_10135	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FY142_10150	COG0583	DNA-binding transcription factor activity
FY142_10160	COG0741	lytic transglycosylase activity
FY142_10185	COG1192	Involved in chromosome partitioning
FY142_10220	COG2814	Major facilitator Superfamily
FY142_10230	COG5489	Protein of unknown function (DUF736)
FY142_10245	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY142_10275	COG1204	response to ionizing radiation
FY142_10290	COG0514	ATP-dependent DNA helicase (RecQ)
FY142_10340	COG0583	DNA-binding transcription factor activity
FY142_10345	COG1902	pentaerythritol trinitrate reductase activity
FY142_10350	COG0583	DNA-binding transcription factor activity
FY142_10365	COG1335	isochorismatase
FY142_10370	COG0583	DNA-binding transcription factor activity
FY142_10375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY142_10385	COG4584	PFAM Integrase catalytic
FY142_10400	COG0840	transmembrane signaling receptor activity
FY142_10415	COG1410	methionine synthase
FY142_10415	COG0646	methionine synthase
FY142_10430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_10460	COG1215	transferase activity, transferring glycosyl groups
FY142_10490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY142_10505	COG2346	COG2346, Truncated hemoglobins
FY142_10525	COG1309	transcriptional regulator
FY142_10540	COG0494	nUDIX hydrolase
FY142_10550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_10555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_10585	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FY142_10590	COG0830	nickel cation binding
FY142_10595	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FY142_10610	COG0804	urea catabolic process
FY142_10615	COG1442	glycosyl transferase family 8
FY142_10620	COG3755	Protein conserved in bacteria
FY142_10630	COG0832	Belongs to the urease beta subunit family
FY142_10635	COG3813	Protein conserved in bacteria
FY142_10640	COG0831	urea catabolic process
FY142_10645	COG0829	nickel cation binding
FY142_10665	COG0411	ABC transporter
FY142_10675	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY142_10690	COG0174	glutamine synthetase
FY142_10695	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_10700	COG0784	Response regulator, receiver
FY142_10700	COG2198	Histidine kinase
FY142_10700	COG5002	protein histidine kinase activity
FY142_10715	COG0726	polysaccharide deacetylase
FY142_10750	COG1218	3'(2'),5'-bisphosphate nucleotidase
FY142_10825	COG0564	pseudouridine synthase activity
FY142_10835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY142_10845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY142_10870	COG0346	lactoylglutathione lyase activity
FY142_10880	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY142_10890	COG2832	Protein of unknown function (DUF454)
FY142_10895	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FY142_10900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_10905	COG4558	Periplasmic binding protein
FY142_10915	COG3721	Heme iron utilization protein
FY142_10930	COG3655	Transcriptional regulator
FY142_10955	COG2205	protein histidine kinase activity
FY142_10995	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_11000	COG4605	iron ion homeostasis
FY142_11005	COG4604	ABC transporter, ATP-binding protein
FY142_11010	COG0783	Belongs to the Dps family
FY142_11025	COG2972	Histidine kinase
FY142_11025	COG0840	transmembrane signaling receptor activity
FY142_11030	COG0656	L-ascorbic acid biosynthetic process
FY142_11035	COG2814	Major facilitator Superfamily
FY142_11045	COG0583	DNA-binding transcription factor activity
FY142_11050	COG0657	acetylesterase activity
FY142_11055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_11075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY142_11080	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FY142_11085	COG0288	reversible hydration of carbon dioxide
FY142_11095	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY142_11115	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FY142_11120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY142_11125	COG0778	Nitroreductase
FY142_11130	COG2267	carboxylic ester hydrolase activity
FY142_11135	COG0251	oxidation-reduction process
FY142_11140	COG1335	isochorismatase
FY142_11145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_11155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_11170	COG1175	transmembrane transport
FY142_11175	COG0395	ABC-type sugar transport system, permease component
FY142_11180	COG3842	ATPase activity
FY142_11185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_11195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY142_11210	COG4608	Belongs to the ABC transporter superfamily
FY142_11215	COG0444	Belongs to the ABC transporter superfamily
FY142_11220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_11225	COG0601	transmembrane transport
FY142_11280	COG2159	amidohydrolase
FY142_11285	COG1960	acyl-CoA dehydrogenase activity
FY142_11315	COG0745	RESPONSE REGULATOR receiver
FY142_11325	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_11325	COG1902	pentaerythritol trinitrate reductase activity
FY142_11330	COG3842	ATPase activity
FY142_11340	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_11345	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_11350	COG0745	RESPONSE REGULATOR receiver
FY142_11360	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY142_11365	COG0583	DNA-binding transcription factor activity
FY142_11370	COG1278	Cold shock
FY142_11410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY142_11415	COG1309	transcriptional regulator
FY142_11420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_11425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_11435	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY142_11440	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FY142_11460	COG0583	DNA-binding transcription factor activity
FY142_11465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_11470	COG0725	ABC transporter, periplasmic molybdate-binding protein
FY142_11475	COG4149	molybdate abc transporter
FY142_11480	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FY142_11495	COG2022	thiamine diphosphate biosynthetic process
FY142_11510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FY142_11520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_11530	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY142_11550	COG1132	(ABC) transporter
FY142_11555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY142_11600	COG4166	transmembrane transport
FY142_11605	COG0601	transmembrane transport
FY142_11610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_11625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY142_11630	COG3142	Participates in the control of copper homeostasis
FY142_11635	COG2814	Major facilitator Superfamily
FY142_11650	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_11655	COG1737	Transcriptional regulator
FY142_11665	COG3842	ATPase activity
FY142_11675	COG0395	ABC-type sugar transport system, permease component
FY142_11695	COG2188	Transcriptional regulator
FY142_11700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY142_11705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FY142_11710	COG1940	carbohydrate kinase activity
FY142_11720	COG0671	phosphoesterase, PA-phosphatase related
FY142_11725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FY142_11730	COG0156	8-amino-7-oxononanoate synthase activity
FY142_11740	COG0729	surface antigen
FY142_11750	COG0835	chemotaxis
FY142_11760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FY142_11765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY142_11770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY142_11775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY142_11780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY142_11785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY142_11800	COG4974	Belongs to the 'phage' integrase family
FY142_11825	COG1280	lysine exporter protein (LysE YggA)
FY142_11835	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY142_11840	COG0567	Dehydrogenase, E1 component
FY142_11845	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FY142_11850	COG0045	succinate-CoA ligase (ADP-forming) activity
FY142_11855	COG0039	L-malate dehydrogenase activity
FY142_11860	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FY142_11910	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY142_11915	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY142_11920	COG0181	hydroxymethylbilane synthase activity
FY142_11960	COG1872	DUF167
FY142_11965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FY142_11975	COG1217	gtp-binding protein TYPA
FY142_11980	COG0339	signal peptide processing
FY142_11985	COG1846	Transcriptional regulator
FY142_11995	COG0137	argininosuccinate synthase activity
FY142_12005	COG1280	lysine exporter protein (LysE YggA)
FY142_12010	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY142_12015	COG4120	Belongs to the binding-protein-dependent transport system permease family
FY142_12025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY142_12040	COG2154	pterin-4-alpha-carbinolamine dehydratase
FY142_12045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY142_12050	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FY142_12060	COG4181	ATPase activity
FY142_12070	COG0670	Belongs to the BI1 family
FY142_12085	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY142_12090	COG4133	protoheme IX ABC transporter activity
FY142_12095	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY142_12100	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FY142_12125	COG2917	probably involved in intracellular septation
FY142_12130	COG0552	protein localization to endoplasmic reticulum
FY142_12135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FY142_12140	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FY142_12155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY142_12160	COG1605	Chorismate mutase
FY142_12160	COG0287	Prephenate dehydrogenase
FY142_12165	COG0228	four-way junction DNA binding
FY142_12170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY142_12175	COG0336	Belongs to the RNA methyltransferase TrmD family
FY142_12185	COG0335	large ribosomal subunit rRNA binding
FY142_12190	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY142_12195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_12210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY142_12230	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FY142_12250	COG0488	(ABC) transporter
FY142_12260	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY142_12270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY142_12275	COG0142	geranyltranstransferase activity
FY142_12280	COG2885	chlorophyll binding
FY142_12285	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FY142_12290	COG2223	nitrite transmembrane transporter activity
FY142_12295	COG1349	DNA-binding transcription factor activity
FY142_12300	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY142_12305	COG2197	response regulator
FY142_12310	COG1132	(ABC) transporter
FY142_12320	COG3459	Glycosyltransferase 36 associated
FY142_12325	COG1473	amidohydrolase
FY142_12330	COG0579	oxidoreductase
FY142_12340	COG0129	dihydroxy-acid dehydratase activity
FY142_12345	COG2084	Dehydrogenase
FY142_12350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_12355	COG0277	FAD linked oxidase domain protein
FY142_12360	COG2186	Transcriptional regulator
FY142_12370	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY142_12375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY142_12380	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_12385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY142_12395	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY142_12400	COG0495	leucyl-tRNA aminoacylation
FY142_12415	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY142_12420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY142_12435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_12440	COG1946	Acyl-CoA thioesterase
FY142_12445	COG0347	Belongs to the P(II) protein family
FY142_12450	COG0004	ammonium transporteR
FY142_12455	COG1674	ftsk spoiiie
FY142_12460	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FY142_12475	COG0745	RESPONSE REGULATOR receiver
FY142_12485	COG1329	Transcriptional regulator
FY142_12495	COG2270	Major facilitator Superfamily
FY142_12510	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_12525	COG0494	nUDIX hydrolase
FY142_12530	COG2861	carbohydrate metabolic process
FY142_12535	COG0793	Belongs to the peptidase S41A family
FY142_12545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY142_12550	COG0799	negative regulation of ribosome biogenesis
FY142_12555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY142_12560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY142_12565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY142_12570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY142_12585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY142_12590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY142_12615	COG0066	3-isopropylmalate dehydratase activity
FY142_12620	COG0473	3-isopropylmalate dehydrogenase activity
FY142_12625	COG1858	cytochrome C peroxidase
FY142_12630	COG1797	cobyrinic acid a,c-diamide synthase activity
FY142_12640	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FY142_12705	COG1492	cobalamin metabolic process
FY142_12720	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_12725	COG3254	rhamnose metabolic process
FY142_12730	COG0246	Mannitol dehydrogenase
FY142_12735	COG1063	alcohol dehydrogenase
FY142_12760	COG1129	ABC transporter
FY142_12765	COG2186	Transcriptional regulator
FY142_12770	COG2721	sulfolactate sulfo-lyase activity
FY142_12775	COG0138	bifunctional purine biosynthesis protein purh
FY142_12785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY142_12785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY142_12790	COG0501	Belongs to the peptidase M48B family
FY142_12810	COG0357	Ribosomal RNA small subunit methyltransferase G
FY142_12815	COG0445	tRNA wobble uridine modification
FY142_12820	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY142_12825	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FY142_12830	COG1981	membrane
FY142_12835	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FY142_12840	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY142_12845	COG0424	maF-like protein
FY142_12850	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY142_12855	COG0237	dephospho-CoA kinase activity
FY142_12865	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FY142_12870	COG3030	protein affecting phage T7 exclusion by the F plasmid
FY142_12880	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FY142_12905	COG0179	Fumarylacetoacetate (FAA) hydrolase
FY142_12920	COG0135	phosphoribosylanthranilate isomerase activity
FY142_12925	COG0133	tryptophan synthase activity
FY142_12930	COG0159	tryptophan synthase activity
FY142_12935	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FY142_12950	COG1074	ATP-dependent DNA helicase activity
FY142_12960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FY142_12965	COG0802	atpase or kinase
FY142_12970	COG2205	protein histidine kinase activity
FY142_12975	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FY142_12980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY142_12985	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY142_12985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY142_12990	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY142_12995	COG0642	Histidine kinase
FY142_13000	COG0745	RESPONSE REGULATOR receiver
FY142_13005	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FY142_13015	COG1652	LysM domain
FY142_13020	COG1072	(Pantothenic acid kinase))
FY142_13025	COG0140	phosphoribosyl-ATP diphosphatase activity
FY142_13030	COG0107	imidazoleglycerol-phosphate synthase activity
FY142_13035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FY142_13040	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY142_13050	COG0131	Imidazoleglycerol-phosphate dehydratase
FY142_13055	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FY142_13060	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FY142_13070	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FY142_13085	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FY142_13095	COG1643	Atp-dependent helicase
FY142_13140	COG1940	carbohydrate kinase activity
FY142_13160	COG1072	(Pantothenic acid kinase))
FY142_13170	COG1780	Probably involved in ribonucleotide reductase function
FY142_13190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY142_13220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_13230	COG2813	Specifically methylates the guanine in position
FY142_13235	COG1185	polyribonucleotide nucleotidyltransferase activity
FY142_13240	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY142_13245	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY142_13250	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY142_13255	COG3064	Membrane
FY142_13255	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY142_13270	COG0779	Required for maturation of 30S ribosomal subunits
FY142_13275	COG2814	Major facilitator Superfamily
FY142_13285	COG2951	lytic endotransglycosylase activity
FY142_13290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY142_13300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY142_13305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY142_13320	COG2816	NAD+ diphosphatase activity
FY142_13325	COG0077	Prephenate dehydratase
FY142_13325	COG1605	Chorismate mutase
FY142_13330	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FY142_13335	COG3474	cytochrome
FY142_13345	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FY142_13350	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY142_13355	COG1278	Cold shock
FY142_13360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_13370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY142_13370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY142_13375	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY142_13405	COG2900	Belongs to the SlyX family
FY142_13415	COG0484	heat shock protein binding
FY142_13420	COG0443	Heat shock 70 kDa protein
FY142_13435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY142_13440	COG1744	ABC transporter substrate-binding protein PnrA-like
FY142_13445	COG3845	ABC transporter
FY142_13450	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY142_13455	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY142_13460	COG0295	cytidine deaminase activity
FY142_13465	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FY142_13470	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY142_13475	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FY142_13485	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY142_13490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY142_13495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FY142_13505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FY142_13510	COG1845	cytochrome c oxidase, subunit III
FY142_13515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY142_13520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY142_13525	COG0477	Major facilitator Superfamily
FY142_13530	COG0070	glutamate synthase
FY142_13530	COG0069	glutamate synthase activity
FY142_13530	COG0067	glutamate synthase
FY142_13535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FY142_13550	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FY142_13560	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY142_13590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_13610	COG0848	biopolymer transport protein
FY142_13620	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY142_13635	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY142_13640	COG3454	Phosphonate metabolism
FY142_13645	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FY142_13650	COG3639	organic phosphonate transmembrane transporter activity
FY142_13655	COG3639	organic phosphonate transmembrane transporter activity
FY142_13665	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY142_13675	COG4778	phosphonate C-P lyase system protein PhnL
FY142_13680	COG4107	phosphonate C-P lyase system protein PhnK
FY142_13685	COG3627	carbon phosphorus lyase activity
FY142_13690	COG3626	phosphonate metabolism
FY142_13695	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FY142_13700	COG3624	Phosphonate C-P lyase system protein PhnG
FY142_13705	COG2188	Transcriptional regulator
FY142_13710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY142_13715	COG0837	glucose binding
FY142_13720	COG1803	Methylglyoxal synthase
FY142_13725	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FY142_13730	COG4166	transmembrane transport
FY142_13735	COG4174	ABC transporter (Permease)
FY142_13740	COG4239	(ABC) transporter, permease
FY142_13745	COG4172	Belongs to the ABC transporter superfamily
FY142_13750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_13755	COG0174	glutamine synthetase
FY142_13760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_13765	COG3265	gluconokinase activity
FY142_13770	COG1174	glycine betaine transport
FY142_13775	COG1125	glycine betaine transport
FY142_13780	COG1174	glycine betaine transport
FY142_13785	COG1732	Glycine betaine
FY142_13795	COG1959	2 iron, 2 sulfur cluster binding
FY142_13800	COG1840	ABC-type Fe3 transport system, periplasmic component
FY142_13810	COG4269	membrane
FY142_13825	COG0697	spore germination
FY142_13840	COG0791	NLP P60 protein
FY142_13850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY142_13855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FY142_13890	COG4964	Belongs to the GSP D family
FY142_13935	COG3422	double-strand break repair
FY142_13940	COG3757	hydrolase, family 25
FY142_13945	COG0697	spore germination
FY142_13950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_13965	COG0492	ferredoxin-NADP+ reductase activity
FY142_13980	COG0481	GTPase activity
FY142_13985	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY142_14000	COG1396	sequence-specific DNA binding
FY142_14015	COG2169	Transcriptional regulator
FY142_14015	COG1917	Cupin 2, conserved barrel domain protein
FY142_14020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY142_14045	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY142_14050	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY142_14055	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY142_14065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FY142_14070	COG0072	phenylalanine-tRNA ligase activity
FY142_14070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY142_14075	COG0667	Aldo Keto reductase
FY142_14095	COG4977	sequence-specific DNA binding
FY142_14120	COG1570	exodeoxyribonuclease VII activity
FY142_14125	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_14135	COG1846	Transcriptional regulator
FY142_14145	COG2309	aminopeptidase activity
FY142_14155	COG1393	Belongs to the ArsC family
FY142_14170	COG1309	transcriptional regulator
FY142_14180	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FY142_14180	COG0519	Catalyzes the synthesis of GMP from XMP
FY142_14195	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FY142_14225	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FY142_14235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY142_14245	COG1968	undecaprenyl-diphosphatase activity
FY142_14260	COG0284	orotidine-5'-phosphate decarboxylase activity
FY142_14270	COG3963	phosphatidate phosphatase activity
FY142_14280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FY142_14285	COG0792	nuclease activity
FY142_14300	COG1175	transmembrane transport
FY142_14305	COG0395	ABC-type sugar transport system, permease component
FY142_14310	COG3842	ATPase activity
FY142_14320	COG0189	ligase activity
FY142_14330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY142_14335	COG1280	lysine exporter protein (LysE YggA)
FY142_14340	COG0756	dUTP diphosphatase activity
FY142_14345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY142_14350	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY142_14365	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FY142_14370	COG2226	methyltransferase
FY142_14375	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY142_14380	COG1024	Enoyl-CoA hydratase
FY142_14385	COG0268	Binds directly to 16S ribosomal RNA
FY142_14395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FY142_14425	COG1278	Cold shock
FY142_14460	COG0411	ABC transporter
FY142_14465	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY142_14470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY142_14475	COG1454	alcohol dehydrogenase
FY142_14480	COG0747	negative chemotaxis
FY142_14485	COG0601	transmembrane transport
FY142_14495	COG4608	Belongs to the ABC transporter superfamily
FY142_14500	COG1349	DNA-binding transcription factor activity
FY142_14505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_14530	COG4302	ethanolamine ammonia-lyase activity
FY142_14535	COG0025	NhaP-type Na H and K H
FY142_14540	COG4106	trans-aconitate 2-methyltransferase activity
FY142_14550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_14555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_14560	COG0601	transmembrane transport
FY142_14585	COG4172	Belongs to the ABC transporter superfamily
FY142_14620	COG0596	Alpha beta hydrolase
FY142_14635	COG1764	response to oxidative stress
FY142_14645	COG0596	Alpha beta hydrolase
FY142_14660	COG0783	Belongs to the Dps family
FY142_14665	COG0243	molybdopterin cofactor binding
FY142_14675	COG4566	intracellular signal transduction
FY142_14680	COG4566	intracellular signal transduction
FY142_14710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_14720	COG1414	Transcriptional regulator
FY142_14735	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_14755	COG1522	sequence-specific DNA binding
FY142_14780	COG0628	permease
FY142_14790	COG2235	arginine
FY142_14825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FY142_14835	COG0702	epimerase
FY142_14840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_14845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_14850	COG0745	RESPONSE REGULATOR receiver
FY142_14855	COG5002	protein histidine kinase activity
FY142_14870	COG2233	PERMEase
FY142_14930	COG0395	ABC-type sugar transport system, permease component
FY142_14935	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_14945	COG3842	ATPase activity
FY142_14980	COG1653	transport
FY142_14990	COG0395	ABC-type sugar transport system, permease component
FY142_14995	COG3842	ATPase activity
FY142_15010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_15015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_15020	COG1116	anion transmembrane transporter activity
FY142_15025	COG0395	ABC-type sugar transport system, permease component
FY142_15030	COG1175	transmembrane transport
FY142_15060	COG1609	Transcriptional regulator
FY142_15075	COG1082	Xylose isomerase domain protein TIM barrel
FY142_15080	COG3842	ATPase activity
FY142_15085	COG0395	ABC-type sugar transport system, permease component
FY142_15090	COG1175	transmembrane transport
FY142_15095	COG1653	transport
FY142_15100	COG1309	transcriptional regulator
FY142_15105	COG0673	inositol 2-dehydrogenase activity
FY142_15120	COG0673	inositol 2-dehydrogenase activity
FY142_15125	COG1278	Cold shock
FY142_15135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY142_15155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY142_15160	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY142_15175	COG3842	ATPase activity
FY142_15180	COG0395	ABC-type sugar transport system, permease component
FY142_15185	COG1175	transmembrane transport
FY142_15195	COG3618	amidohydrolase
FY142_15200	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_15205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_15210	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_15215	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FY142_15220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_15225	COG2186	Transcriptional regulator
FY142_15240	COG0667	Aldo Keto reductase
FY142_15270	COG4977	sequence-specific DNA binding
FY142_15275	COG2223	nitrite transmembrane transporter activity
FY142_15280	COG1609	Transcriptional regulator
FY142_15285	COG1063	alcohol dehydrogenase
FY142_15290	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_15300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_15305	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
FY142_15310	COG1175	transmembrane transport
FY142_15315	COG0395	ABC-type sugar transport system, permease component
FY142_15330	COG0395	ABC-type sugar transport system, permease component
FY142_15340	COG2182	Extracellular solute-binding protein
FY142_15345	COG0626	cystathionine gamma-synthase activity
FY142_15360	COG0454	-acetyltransferase
FY142_15365	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY142_15375	COG1121	(ABC) transporter
FY142_15380	COG0523	cobalamin synthesis protein
FY142_15395	COG0523	cobalamin synthesis protein
FY142_15400	COG1653	transport
FY142_15405	COG1175	transmembrane transport
FY142_15410	COG0395	ABC-type sugar transport system, permease component
FY142_15415	COG3842	ATPase activity
FY142_15425	COG3047	cAMP biosynthetic process
FY142_15450	COG0583	DNA-binding transcription factor activity
FY142_15455	COG1879	ABC-type sugar transport system periplasmic component
FY142_15460	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_15465	COG1129	ABC transporter
FY142_15475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FY142_15480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_15490	COG3257	ureidoglycine aminohydrolase activity
FY142_15500	COG5001	Diguanylate cyclase
FY142_15505	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY142_15515	COG0747	negative chemotaxis
FY142_15520	COG0601	transmembrane transport
FY142_15525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_15535	COG4608	Belongs to the ABC transporter superfamily
FY142_15540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FY142_15555	COG0346	lactoylglutathione lyase activity
FY142_15565	COG0129	dihydroxy-acid dehydratase activity
FY142_15570	COG1879	ABC-type sugar transport system periplasmic component
FY142_15575	COG1129	ABC transporter
FY142_15580	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_15585	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_15590	COG2186	Transcriptional regulator
FY142_15605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY142_15610	COG0587	DNA-directed DNA polymerase activity
FY142_15640	COG0673	inositol 2-dehydrogenase activity
FY142_15650	COG3842	ATPase activity
FY142_15655	COG0395	ABC-type sugar transport system, permease component
FY142_15660	COG1175	transmembrane transport
FY142_15665	COG1653	transport
FY142_15675	COG0673	inositol 2-dehydrogenase activity
FY142_15690	COG5001	Diguanylate cyclase
FY142_15700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_15705	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FY142_15710	COG2894	cell division
FY142_15715	COG0850	regulation of cytokinetic process
FY142_15720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY142_15725	COG2186	Transcriptional regulator
FY142_15730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_15740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY142_15745	COG1063	alcohol dehydrogenase
FY142_15750	COG1312	Catalyzes the dehydration of D-mannonate
FY142_15770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FY142_15775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FY142_15775	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY142_15780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_15795	COG0625	glutathione transferase activity
FY142_15800	COG4172	Belongs to the ABC transporter superfamily
FY142_15805	COG1921	L-seryl-tRNASec selenium transferase activity
FY142_15820	COG3964	amidohydrolase
FY142_15830	COG0601	transmembrane transport
FY142_15835	COG0747	negative chemotaxis
FY142_15840	COG0438	transferase activity, transferring glycosyl groups
FY142_15875	COG4989	oxidoreductase activity
FY142_15885	COG2188	Transcriptional regulator
FY142_15890	COG3842	ATPase activity
FY142_15895	COG1653	transport
FY142_15900	COG1175	transmembrane transport
FY142_15905	COG0395	ABC-type sugar transport system, permease component
FY142_15910	COG1501	Belongs to the glycosyl hydrolase 31 family
FY142_15920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_15925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_15930	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FY142_15935	COG0352	thiamine-phosphate diphosphorylase activity
FY142_15940	COG0351	phosphomethylpyrimidine kinase
FY142_15945	COG1522	sequence-specific DNA binding
FY142_15950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY142_15955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_15970	COG2204	response regulator
FY142_15975	COG4191	Histidine kinase
FY142_15980	COG1301	dicarboxylic acid transport
FY142_15985	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY142_15990	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_16000	COG1473	amidohydrolase
FY142_16020	COG1215	transferase activity, transferring glycosyl groups
FY142_16030	COG2942	2-epimerase
FY142_16055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_16065	COG2197	response regulator
FY142_16095	COG3307	-O-antigen
FY142_16100	COG1596	polysaccharide export
FY142_16105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FY142_16115	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY142_16120	COG0840	transmembrane signaling receptor activity
FY142_16125	COG1376	ErfK ybiS ycfS ynhG family protein
FY142_16135	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_16145	COG2094	Belongs to the DNA glycosylase MPG family
FY142_16160	COG1609	Transcriptional regulator
FY142_16165	COG1653	transport
FY142_16180	COG3842	ATPase activity
FY142_16190	COG0673	inositol 2-dehydrogenase activity
FY142_16195	COG0602	queuosine metabolic process
FY142_16200	COG0720	synthase
FY142_16205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY142_16210	COG0673	inositol 2-dehydrogenase activity
FY142_16225	COG0395	ABC-type sugar transport system, permease component
FY142_16230	COG1175	transmembrane transport
FY142_16255	COG0583	DNA-binding transcription factor activity
FY142_16260	COG0280	phosphate acetyltransferase
FY142_16260	COG0281	malic enzyme
FY142_16275	COG0765	amino acid transport
FY142_16280	COG1126	abc transporter atp-binding protein
FY142_16285	COG2079	MmgE PrpD family protein
FY142_16290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_16315	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FY142_16325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FY142_16330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY142_16335	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_16340	COG1129	ABC transporter
FY142_16355	COG1473	amidohydrolase
FY142_16360	COG0747	negative chemotaxis
FY142_16375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_16380	COG0601	transmembrane transport
FY142_16385	COG0583	DNA-binding transcription factor activity
FY142_16390	COG1446	asparaginase
FY142_16405	COG0747	negative chemotaxis
FY142_16425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_16430	COG0601	transmembrane transport
FY142_16435	COG2197	response regulator
FY142_16440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_16445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_16455	COG3842	ATPase activity
FY142_16460	COG0395	ABC-type sugar transport system, permease component
FY142_16465	COG1175	transmembrane transport
FY142_16475	COG0673	inositol 2-dehydrogenase activity
FY142_16480	COG0673	inositol 2-dehydrogenase activity
FY142_16500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_16505	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
FY142_16525	COG1595	DNA-templated transcription, initiation
FY142_16530	COG1120	ATPase activity
FY142_16535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_16550	COG2226	methyltransferase
FY142_16560	COG1120	ATPase activity
FY142_16565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_16610	COG1012	belongs to the aldehyde dehydrogenase family
FY142_16615	COG0473	3-isopropylmalate dehydrogenase activity
FY142_16620	COG1012	belongs to the aldehyde dehydrogenase family
FY142_16625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_16660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_16665	COG4172	Belongs to the ABC transporter superfamily
FY142_16670	COG1522	sequence-specific DNA binding
FY142_16680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_16695	COG0583	DNA-binding transcription factor activity
FY142_16705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_16710	COG1126	abc transporter atp-binding protein
FY142_16720	COG1473	amidohydrolase
FY142_16725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16735	COG1959	2 iron, 2 sulfur cluster binding
FY142_16745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY142_16750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16780	COG1960	acyl-CoA dehydrogenase activity
FY142_16790	COG0747	negative chemotaxis
FY142_16805	COG0444	Belongs to the ABC transporter superfamily
FY142_16815	COG0667	Aldo Keto reductase
FY142_16825	COG0583	DNA-binding transcription factor activity
FY142_16830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16835	COG4166	transmembrane transport
FY142_16850	COG0747	negative chemotaxis
FY142_16855	COG1473	amidohydrolase
FY142_16860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_16890	COG1733	regulation of RNA biosynthetic process
FY142_16895	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_17030	COG4373	Mu-like prophage FluMu protein gp28
FY142_17035	COG4383	Mu-like prophage protein gp29
FY142_17040	COG2369	cell adhesion
FY142_17170	COG4608	Belongs to the ABC transporter superfamily
FY142_17175	COG0444	Belongs to the ABC transporter superfamily
FY142_17185	COG0601	transmembrane transport
FY142_17195	COG2186	Transcriptional regulator
FY142_17210	COG0300	oxidoreductase activity
FY142_17220	COG3453	Protein conserved in bacteria
FY142_17220	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY142_17225	COG0640	Transcriptional regulator
FY142_17235	COG2391	methyltransferase activity
FY142_17240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FY142_17250	COG0022	dehydrogenase e1 component
FY142_17260	COG1960	acyl-CoA dehydrogenase activity
FY142_17265	COG0183	Belongs to the thiolase family
FY142_17275	COG1960	acyl-CoA dehydrogenase activity
FY142_17280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY142_17300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FY142_17305	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FY142_17310	COG4952	isomerase
FY142_17315	COG3347	Dehydrogenase
FY142_17315	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_17320	COG1349	DNA-binding transcription factor activity
FY142_17330	COG1129	ABC transporter
FY142_17335	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_17340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_17345	COG3254	rhamnose metabolic process
FY142_17360	COG2264	protein methyltransferase activity
FY142_17365	COG5001	Diguanylate cyclase
FY142_17380	COG4335	DNA alkylation repair
FY142_17385	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY142_17390	COG4208	sulfate ABC transporter
FY142_17400	COG4150	thiosulfate binding
FY142_17405	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FY142_17420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY142_17430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY142_17440	COG1040	competence protein
FY142_17445	COG2226	methyltransferase
FY142_17460	COG0494	nUDIX hydrolase
FY142_17470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY142_17475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY142_17480	COG0653	protein targeting
FY142_17485	COG0697	spore germination
FY142_17550	COG2244	polysaccharide biosynthetic process
FY142_17565	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY142_17575	COG0489	protein tyrosine kinase activity
FY142_17575	COG3206	protein involved in exopolysaccharide biosynthesis
FY142_17595	COG0438	transferase activity, transferring glycosyl groups
FY142_17600	COG0438	transferase activity, transferring glycosyl groups
FY142_17615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY142_17620	COG2273	Hydrolase Family 16
FY142_17620	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
FY142_17635	COG3842	ATPase activity
FY142_17640	COG3833	ABC-type maltose transport systems, permease component
FY142_17695	COG1396	sequence-specific DNA binding
FY142_17705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY142_17710	COG1129	ABC transporter
FY142_17715	COG4214	carbohydrate transport
FY142_17720	COG4213	ABC transporter substrate-binding protein
FY142_17735	COG0346	lactoylglutathione lyase activity
FY142_17740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY142_17740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FY142_17745	COG4770	biotin carboxylase activity
FY142_17760	COG0625	glutathione transferase activity
FY142_17765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FY142_17770	COG1396	sequence-specific DNA binding
FY142_17770	COG3800	Transcriptional regulator
FY142_17780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY142_17790	COG0300	oxidoreductase activity
FY142_17800	COG2096	Adenosyltransferase
FY142_17810	COG2086	electron transfer activity
FY142_17820	COG1250	3-hydroxyacyl-CoA dehydrogenase
FY142_17830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY142_17835	COG0165	Argininosuccinate lyase
FY142_17870	COG2884	Cell division ATP-binding protein ftsE
FY142_17890	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY142_17900	COG0287	Prephenate dehydrogenase
FY142_17905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY142_17910	COG2226	methyltransferase
FY142_17915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FY142_17935	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY142_17940	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FY142_17980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY142_17985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY142_17995	COG4974	Belongs to the 'phage' integrase family
FY142_18000	COG0825	malonyl-CoA metabolic process
FY142_18005	COG3034	peptidoglycan biosynthetic process
FY142_18010	COG0425	Belongs to the sulfur carrier protein TusA family
FY142_18010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY142_18015	COG0523	cobalamin synthesis protein
FY142_18020	COG1686	Belongs to the peptidase S11 family
FY142_18025	COG1473	amidohydrolase
FY142_18035	COG4953	penicillin-binding protein 1C
FY142_18040	COG2373	Large extracellular alpha-helical protein
FY142_18045	COG2835	tetraacyldisaccharide 4'-kinase activity
FY142_18075	COG0482	sulfurtransferase activity
FY142_18090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY142_18105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY142_18110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY142_18115	COG0037	tRNA processing
FY142_18125	COG2885	chlorophyll binding
FY142_18130	COG0823	Involved in the tonB-independent uptake of proteins
FY142_18150	COG0824	Thioesterase
FY142_18160	COG0494	nUDIX hydrolase
FY142_18175	COG2255	four-way junction helicase activity
FY142_18180	COG0632	four-way junction helicase activity
FY142_18185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FY142_18190	COG0840	transmembrane signaling receptor activity
FY142_18195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_18200	COG0217	transcriptional regulatory protein
FY142_18215	COG1692	metallophosphoesterase
FY142_18225	COG1253	flavin adenine dinucleotide binding
FY142_18265	COG0126	phosphoglycerate kinase activity
FY142_18270	COG3588	fructose-bisphosphate aldolase
FY142_18290	COG0254	rRNA binding
FY142_18295	COG1132	(ABC) transporter
FY142_18315	COG0483	inositol monophosphate 1-phosphatase activity
FY142_18345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY142_18350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FY142_18355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FY142_18360	COG0457	Tetratricopeptide repeat
FY142_18365	COG3750	Belongs to the UPF0335 family
FY142_18385	COG0469	pyruvate kinase activity
FY142_18390	COG3108	Peptidase M15
FY142_18395	COG2204	response regulator
FY142_18400	COG1164	Oligoendopeptidase f
FY142_18405	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY142_18415	COG5310	Homospermidine synthase
FY142_18425	COG0737	Belongs to the 5'-nucleotidase family
FY142_18430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FY142_18435	COG0330	HflC and HflK could
FY142_18460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY142_18465	COG2951	lytic endotransglycosylase activity
FY142_18480	COG2205	protein histidine kinase activity
FY142_18495	COG0070	glutamate synthase
FY142_18495	COG0067	glutamate synthase
FY142_18495	COG0069	glutamate synthase activity
FY142_18510	COG2205	protein histidine kinase activity
FY142_18515	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FY142_18520	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FY142_18525	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FY142_18535	COG0252	asparaginase activity
FY142_18545	COG1027	Aspartate ammonia-lyase
FY142_18550	COG2186	Transcriptional regulator
FY142_18590	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_18595	COG0517	IMP dehydrogenase activity
FY142_18595	COG4175	Glycine betaine
FY142_18600	COG2986	histidine ammonia-lyase
FY142_18605	COG1609	Transcriptional regulator
FY142_18625	COG1082	Xylose isomerase domain protein TIM barrel
FY142_18630	COG0673	inositol 2-dehydrogenase activity
FY142_18635	COG1082	Xylose isomerase domain protein TIM barrel
FY142_18660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY142_18705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_18715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_18720	COG0601	transmembrane transport
FY142_18725	COG0747	negative chemotaxis
FY142_18735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY142_18740	COG1454	alcohol dehydrogenase
FY142_18780	COG2307	Protein conserved in bacteria
FY142_18780	COG2308	Evidence 4 Homologs of previously reported genes of
FY142_18795	COG0488	(ABC) transporter
FY142_18800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_18805	COG2186	Transcriptional regulator
FY142_18820	COG1175	transmembrane transport
FY142_18825	COG0395	ABC-type sugar transport system, permease component
FY142_18835	COG3842	ATPase activity
FY142_18860	COG1304	FMN binding
FY142_18875	COG1063	alcohol dehydrogenase
FY142_18880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_18885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_18895	COG0765	amino acid transport
FY142_18900	COG0765	amino acid transport
FY142_18905	COG4221	oxidoreductase activity
FY142_18910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_18915	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_18920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_18935	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_18950	COG0697	spore germination
FY142_18955	COG0697	spore germination
FY142_18960	COG0511	ligase activity, forming carbon-carbon bonds
FY142_18965	COG0439	Biotin carboxylase
FY142_18975	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_18980	COG1984	allophanate hydrolase subunit 2
FY142_18985	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_18990	COG3842	ATPase activity
FY142_19000	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FY142_19010	COG0436	Aminotransferase
FY142_19025	COG0840	transmembrane signaling receptor activity
FY142_19030	COG1070	Carbohydrate kinase
FY142_19035	COG1830	Aldolase
FY142_19040	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY142_19045	COG0667	Aldo Keto reductase
FY142_19055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_19060	COG1129	ABC transporter
FY142_19065	COG1879	ABC-type sugar transport system periplasmic component
FY142_19110	COG0071	Belongs to the small heat shock protein (HSP20) family
FY142_19125	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY142_19140	COG0395	ABC-type sugar transport system, permease component
FY142_19155	COG3842	ATPase activity
FY142_19170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FY142_19170	COG1648	precorrin-2 dehydrogenase activity
FY142_19175	COG0243	molybdopterin cofactor binding
FY142_19185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FY142_19190	COG1116	anion transmembrane transporter activity
FY142_19195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_19200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_19210	COG3707	response regulator
FY142_19215	COG1802	Transcriptional regulator
FY142_19220	COG1914	H( )-stimulated, divalent metal cation uptake system
FY142_19225	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_19230	COG4336	lyase activity
FY142_19235	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY142_19240	COG4770	biotin carboxylase activity
FY142_19245	COG0366	Alpha amylase catalytic
FY142_19255	COG4771	TonB-dependent receptor
FY142_19260	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY142_19280	COG1414	Transcriptional regulator
FY142_19285	COG1475	DNA binding
FY142_19290	COG1192	Involved in chromosome partitioning
FY142_19320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FY142_19330	COG2986	histidine ammonia-lyase
FY142_19335	COG1228	amidohydrolase
FY142_19340	COG0402	S-adenosylhomocysteine deaminase activity
FY142_19380	COG4172	Belongs to the ABC transporter superfamily
FY142_19385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_19390	COG0601	transmembrane transport
FY142_19395	COG4166	transmembrane transport
FY142_19400	COG0395	ABC-type sugar transport system, permease component
FY142_19420	COG1566	PFAM secretion protein HlyD family protein
FY142_19435	COG2207	Transcriptional regulator
FY142_19440	COG1309	transcriptional regulator
FY142_19445	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_19470	COG1846	Transcriptional regulator
FY142_19475	COG0583	DNA-binding transcription factor activity
FY142_19480	COG2828	Protein conserved in bacteria
FY142_19495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_19510	COG0840	transmembrane signaling receptor activity
FY142_19530	COG1215	transferase activity, transferring glycosyl groups
FY142_19560	COG0583	DNA-binding transcription factor activity
FY142_19565	COG0346	lactoylglutathione lyase activity
FY142_19580	COG1574	metal-dependent hydrolase with the TIM-barrel fold
FY142_19600	COG0583	DNA-binding transcription factor activity
FY142_19605	COG0477	Major facilitator Superfamily
FY142_19615	COG2205	protein histidine kinase activity
FY142_19620	COG0745	RESPONSE REGULATOR receiver
FY142_19625	COG0671	phosphoesterase, PA-phosphatase related
FY142_19675	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FY142_19680	COG0156	8-amino-7-oxononanoate synthase activity
FY142_19685	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FY142_19690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY142_19695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY142_19710	COG0010	Belongs to the arginase family
FY142_19720	COG0697	spore germination
FY142_19725	COG0673	inositol 2-dehydrogenase activity
FY142_19750	COG0477	Major facilitator Superfamily
FY142_19765	COG2194	sulfuric ester hydrolase activity
FY142_19775	COG0583	DNA-binding transcription factor activity
FY142_19780	COG4774	siderophore transport
FY142_19795	COG1120	ATPase activity
FY142_19805	COG3474	cytochrome
FY142_19810	COG2137	regulation of response to DNA damage stimulus
FY142_19815	COG3386	PFAM SMP-30 Gluconolaconase
FY142_19825	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_19830	COG1129	ABC transporter
FY142_19835	COG1879	ABC-type sugar transport system periplasmic component
FY142_19840	COG4585	Histidine kinase
FY142_19845	COG2197	response regulator
FY142_19855	COG2133	pyrroloquinoline quinone binding
FY142_19865	COG0500	methyltransferase
FY142_19870	COG0564	pseudouridine synthase activity
FY142_19885	COG4175	Glycine betaine
FY142_19885	COG3448	diguanylate cyclase activity
FY142_19890	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_19905	COG0784	Response regulator, receiver
FY142_19905	COG4191	Histidine kinase
FY142_19910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY142_19915	COG3206	protein involved in exopolysaccharide biosynthesis
FY142_19915	COG0489	protein tyrosine kinase activity
FY142_19920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY142_19925	COG1215	transferase activity, transferring glycosyl groups
FY142_19930	COG1215	transferase activity, transferring glycosyl groups
FY142_19935	COG1215	transferase activity, transferring glycosyl groups
FY142_19940	COG0438	transferase activity, transferring glycosyl groups
FY142_19945	COG2273	Hydrolase Family 16
FY142_19950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FY142_19955	COG2244	polysaccharide biosynthetic process
FY142_19960	COG0463	Glycosyl transferase, family 2
FY142_19965	COG2327	Polysaccharide pyruvyl transferase
FY142_19970	COG1215	transferase activity, transferring glycosyl groups
FY142_19990	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FY142_19995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_20010	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_20010	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_20040	COG1523	belongs to the glycosyl hydrolase 13 family
FY142_20045	COG0033	Phosphoglucomutase
FY142_20050	COG0297	glycogen (starch) synthase activity
FY142_20055	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY142_20060	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY142_20065	COG0058	SHG alpha-glucan phosphorylase activity
FY142_20080	COG1794	racemase activity, acting on amino acids and derivatives
FY142_20085	COG1522	sequence-specific DNA binding
FY142_20095	COG2084	Dehydrogenase
FY142_20100	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_20105	COG1063	alcohol dehydrogenase
FY142_20115	COG4988	ABC transporter
FY142_20120	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FY142_20130	COG1294	oxidase, subunit
FY142_20160	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FY142_20165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FY142_20195	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY142_20200	COG0539	negative regulation of cytoplasmic translation
FY142_20230	COG4221	oxidoreductase activity
FY142_20240	COG0747	negative chemotaxis
FY142_20245	COG0601	transmembrane transport
FY142_20250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_20255	COG0444	Belongs to the ABC transporter superfamily
FY142_20260	COG4608	Belongs to the ABC transporter superfamily
FY142_20265	COG0246	Mannitol dehydrogenase
FY142_20280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_20325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FY142_20330	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_20345	COG4993	Dehydrogenase
FY142_20350	COG3685	Protein conserved in bacteria
FY142_20380	COG0693	protein deglycase activity
FY142_20400	COG0189	ligase activity
FY142_20405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FY142_20410	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FY142_20425	COG0435	Glutathione S-transferase
FY142_20430	COG0583	DNA-binding transcription factor activity
FY142_20435	COG1012	belongs to the aldehyde dehydrogenase family
FY142_20440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FY142_20445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FY142_20450	COG1116	anion transmembrane transporter activity
FY142_20460	COG1522	sequence-specific DNA binding
FY142_20475	COG0784	Response regulator, receiver
FY142_20495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY142_20510	COG0019	diaminopimelate decarboxylase activity
FY142_20525	COG0527	aspartate kinase activity
FY142_20535	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY142_20540	COG2890	protein-(glutamine-N5) methyltransferase activity
FY142_20550	COG0542	response to heat
FY142_20555	COG1196	nuclear chromosome segregation
FY142_20555	COG0739	heme binding
FY142_20555	COG0741	lytic transglycosylase activity
FY142_20600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY142_20610	COG1280	lysine exporter protein (LysE YggA)
FY142_20625	COG1309	transcriptional regulator
FY142_20630	COG4221	oxidoreductase activity
FY142_20635	COG1902	pentaerythritol trinitrate reductase activity
FY142_20640	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_20680	COG1278	Cold shock
FY142_20700	COG0753	catalase activity
FY142_20725	COG3920	Histidine kinase
FY142_20730	COG1280	lysine exporter protein (LysE YggA)
FY142_20750	COG0583	DNA-binding transcription factor activity
FY142_20785	COG0583	DNA-binding transcription factor activity
FY142_20795	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_20800	COG1846	Transcriptional regulator
FY142_20820	COG2186	Transcriptional regulator
FY142_20830	COG1126	abc transporter atp-binding protein
FY142_20840	COG0765	amino acid transport
FY142_20845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_20860	COG0436	Aminotransferase
FY142_20865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_20895	COG0405	Gamma-glutamyltransferase
FY142_20905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FY142_20910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_20915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_20925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_20930	COG0747	negative chemotaxis
FY142_20935	COG0747	negative chemotaxis
FY142_20945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_20955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_20965	COG1129	ABC transporter
FY142_20970	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_20975	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_21000	COG0667	Aldo Keto reductase
FY142_21015	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_21020	COG1129	ABC transporter
FY142_21025	COG4213	ABC transporter substrate-binding protein
FY142_21045	COG4608	Belongs to the ABC transporter superfamily
FY142_21050	COG0444	Belongs to the ABC transporter superfamily
FY142_21055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_21060	COG0601	transmembrane transport
FY142_21065	COG0747	negative chemotaxis
FY142_21090	COG0765	amino acid transport
FY142_21095	COG4597	amino acid ABC transporter
FY142_21100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_21115	COG3177	Filamentation induced by cAMP protein fic
FY142_21140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_21170	COG3209	COG3209 Rhs family protein
FY142_21190	COG0745	RESPONSE REGULATOR receiver
FY142_21200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_21205	COG0577	efflux transmembrane transporter activity
FY142_21205	COG1136	(ABC) transporter
FY142_21215	COG1733	regulation of RNA biosynthetic process
FY142_21250	COG0534	Mate efflux family protein
FY142_21265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY142_21270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY142_21280	COG1566	PFAM secretion protein HlyD family protein
FY142_21290	COG0625	glutathione transferase activity
FY142_21295	COG4221	oxidoreductase activity
FY142_21305	COG2376	Dihydroxyacetone kinase
FY142_21310	COG1522	sequence-specific DNA binding
FY142_21330	COG0431	NADPH-dependent FMN reductase
FY142_21340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_21350	COG4172	Belongs to the ABC transporter superfamily
FY142_21355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_21375	COG0277	FAD linked oxidase domain protein
FY142_21395	COG0778	Nitroreductase
FY142_21425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY142_21450	COG2318	DinB family
FY142_21455	COG0583	DNA-binding transcription factor activity
FY142_21470	COG1335	isochorismatase
FY142_21495	COG3842	ATPase activity
FY142_21500	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_21505	COG1177	transmembrane transport
FY142_21510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FY142_21520	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FY142_21535	COG1120	ATPase activity
FY142_21540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_21545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_21550	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FY142_21555	COG4774	siderophore transport
FY142_21555	COG1629	transport
FY142_21560	COG4702	Belongs to the UPF0303 family
FY142_21580	COG1024	Enoyl-CoA hydratase
FY142_21585	COG1012	belongs to the aldehyde dehydrogenase family
FY142_21590	COG1653	transport
FY142_21595	COG1175	transmembrane transport
FY142_21600	COG0395	ABC-type sugar transport system, permease component
FY142_21605	COG3842	ATPase activity
FY142_21635	COG3474	cytochrome
FY142_21640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FY142_21645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FY142_21650	COG1845	cytochrome c oxidase, subunit III
FY142_21675	COG1136	(ABC) transporter
FY142_21675	COG0577	efflux transmembrane transporter activity
FY142_21730	COG3842	ATPase activity
FY142_21740	COG1177	transmembrane transport
FY142_21745	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_21760	COG1940	carbohydrate kinase activity
FY142_21780	COG1069	ribulokinase activity
FY142_21785	COG1349	DNA-binding transcription factor activity
FY142_21790	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_21815	COG0395	ABC-type sugar transport system, permease component
FY142_21825	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_21840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY142_21845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FY142_21855	COG0477	Major facilitator Superfamily
FY142_21905	COG1733	regulation of RNA biosynthetic process
FY142_21940	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY142_21945	COG3938	Belongs to the proline racemase family
FY142_21950	COG4176	ABC-type proline glycine betaine transport system permease component
FY142_21960	COG4175	Glycine betaine
FY142_21960	COG3448	diguanylate cyclase activity
FY142_21970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_21975	COG1012	belongs to the aldehyde dehydrogenase family
FY142_21980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_21990	COG0047	phosphoribosylformylglycinamidine synthase activity
FY142_21995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_22005	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_22005	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_22015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY142_22035	COG1309	transcriptional regulator
FY142_22050	COG1136	(ABC) transporter
FY142_22065	COG1063	alcohol dehydrogenase
FY142_22075	COG1879	ABC-type sugar transport system periplasmic component
FY142_22085	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_22105	COG0477	Major facilitator Superfamily
FY142_22235	COG5001	Diguanylate cyclase
FY142_22235	COG3300	MHYT domain
FY142_22260	COG1253	flavin adenine dinucleotide binding
FY142_22275	COG3842	ATPase activity
FY142_22280	COG0395	ABC-type sugar transport system, permease component
FY142_22285	COG1175	transmembrane transport
FY142_22290	COG1653	transport
FY142_22300	COG0673	inositol 2-dehydrogenase activity
FY142_22305	COG1609	Transcriptional regulator
FY142_22320	COG0583	DNA-binding transcription factor activity
FY142_22330	COG1879	ABC-type sugar transport system periplasmic component
FY142_22335	COG1129	ABC transporter
FY142_22340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_22345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_22350	COG1609	Transcriptional regulator
FY142_22360	COG0673	inositol 2-dehydrogenase activity
FY142_22420	COG0714	Associated with various cellular activities
FY142_22425	COG3256	nitric oxide reductase
FY142_22455	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FY142_22460	COG3189	MarR family transcriptional regulator
FY142_22470	COG0826	peptidase U32
FY142_22505	COG4459	periplasmic nitrate reductase
FY142_22520	COG0243	molybdopterin cofactor binding
FY142_22530	COG3005	denitrification pathway
FY142_22545	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_22550	COG1535	isochorismatase
FY142_22550	COG3433	isochorismatase activity
FY142_22555	COG1021	2,3-dihydroxybenzoate-AMP ligase
FY142_22560	COG1169	isochorismate synthase
FY142_22570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY142_22570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FY142_22575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY142_22585	COG2375	cellular response to nickel ion
FY142_22595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_22600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_22610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_22620	COG1629	transport
FY142_22620	COG4774	siderophore transport
FY142_22625	COG1960	acyl-CoA dehydrogenase activity
FY142_22630	COG0583	DNA-binding transcription factor activity
FY142_22635	COG1609	Transcriptional regulator
FY142_22645	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_22655	COG3842	ATPase activity
FY142_22665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FY142_22670	COG0583	DNA-binding transcription factor activity
FY142_22675	COG2814	Major facilitator Superfamily
FY142_22680	COG1473	amidohydrolase
FY142_22695	COG0747	negative chemotaxis
FY142_22700	COG0601	transmembrane transport
FY142_22705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_22710	COG0444	Belongs to the ABC transporter superfamily
FY142_22715	COG4608	Belongs to the ABC transporter superfamily
FY142_22720	COG0583	DNA-binding transcription factor activity
FY142_22725	COG0747	negative chemotaxis
FY142_22735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_22740	COG0154	amidase activity
FY142_22745	COG0693	protein deglycase activity
FY142_22755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_22760	COG0601	transmembrane transport
FY142_22770	COG1473	amidohydrolase
FY142_22775	COG4172	Belongs to the ABC transporter superfamily
FY142_22780	COG2390	Transcriptional regulator
FY142_22790	COG1175	transmembrane transport
FY142_22795	COG0395	ABC-type sugar transport system, permease component
FY142_22845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY142_22865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FY142_22870	COG1414	Transcriptional regulator
FY142_22875	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_22885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY142_22890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY142_22895	COG1121	(ABC) transporter
FY142_22900	COG0803	Belongs to the bacterial solute-binding protein 9 family
FY142_22910	COG1752	Esterase of the alpha-beta hydrolase superfamily
FY142_22915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY142_22920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY142_22925	COG3273	potassium ion transport
FY142_22925	COG0471	metal ion transport
FY142_22930	COG1253	flavin adenine dinucleotide binding
FY142_22935	COG1309	transcriptional regulator
FY142_22955	COG1609	Transcriptional regulator
FY142_22960	COG1070	Carbohydrate kinase
FY142_22965	COG2115	Belongs to the xylose isomerase family
FY142_22975	COG0778	Nitroreductase
FY142_22980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY142_22985	COG2011	ABC-type metal ion transport system permease component
FY142_22995	COG3300	MHYT domain
FY142_22995	COG5001	Diguanylate cyclase
FY142_23000	COG1054	Belongs to the UPF0176 family
FY142_23010	COG2954	triphosphatase activity
FY142_23015	COG0800	Aldolase
FY142_23035	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FY142_23075	COG0523	cobalamin synthesis protein
FY142_23085	COG1846	Transcriptional regulator
FY142_23090	COG1609	Transcriptional regulator
FY142_23095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_23105	COG3718	enzyme involved in inositol metabolism
FY142_23115	COG3962	Belongs to the TPP enzyme family
FY142_23120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_23135	COG0411	ABC transporter
FY142_23150	COG0683	leucine binding
FY142_23165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_23175	COG0747	negative chemotaxis
FY142_23180	COG4172	Belongs to the ABC transporter superfamily
FY142_23205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FY142_23210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY142_23215	COG1126	abc transporter atp-binding protein
FY142_23220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_23225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_23230	COG0765	amino acid transport
FY142_23235	COG0765	amino acid transport
FY142_23240	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY142_23245	COG3485	protocatechuate 3,4-dioxygenase
FY142_23250	COG3485	protocatechuate 3,4-dioxygenase
FY142_23255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY142_23265	COG0583	DNA-binding transcription factor activity
FY142_23280	COG1414	Transcriptional regulator
FY142_23290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FY142_23295	COG0183	Belongs to the thiolase family
FY142_23300	COG1609	Transcriptional regulator
FY142_23315	COG1082	Xylose isomerase domain protein TIM barrel
FY142_23320	COG0673	inositol 2-dehydrogenase activity
FY142_23330	COG1609	Transcriptional regulator
FY142_23335	COG0395	ABC-type sugar transport system, permease component
FY142_23340	COG1175	transmembrane transport
FY142_23345	COG3842	ATPase activity
FY142_23355	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FY142_23375	COG2814	Major facilitator Superfamily
FY142_23380	COG4774	siderophore transport
FY142_23385	COG3712	iron ion homeostasis
FY142_23395	COG1940	carbohydrate kinase activity
FY142_23400	COG0584	glycerophosphoryl diester phosphodiesterase
FY142_23405	COG0300	oxidoreductase activity
FY142_23420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FY142_23440	COG0667	Aldo Keto reductase
FY142_23445	COG0583	DNA-binding transcription factor activity
FY142_23455	COG1132	(ABC) transporter
FY142_23470	COG1442	glycosyl transferase family 8
FY142_23470	COG1216	Glycosyl transferase, family 2
FY142_23475	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FY142_23485	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FY142_23505	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FY142_23510	COG3754	Rhamnan synthesis protein F
FY142_23525	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY142_23530	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY142_23535	COG1088	dTDP-glucose 4,6-dehydratase activity
FY142_23540	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
FY142_23545	COG0210	DNA helicase
FY142_23555	COG1609	Transcriptional regulator
FY142_23560	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY142_23560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_23575	COG0395	ABC-type sugar transport system, permease component
FY142_23580	COG3842	ATPase activity
FY142_23590	COG0444	Belongs to the ABC transporter superfamily
FY142_23595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_23600	COG0601	transmembrane transport
FY142_23605	COG2186	Transcriptional regulator
FY142_23625	COG3300	MHYT domain
FY142_23625	COG5001	Diguanylate cyclase
FY142_23630	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_23640	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY142_23650	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FY142_23655	COG0306	phosphate transporter
FY142_23660	COG1392	Phosphate transport regulator
FY142_23675	COG1566	PFAM secretion protein HlyD family protein
FY142_23680	COG0745	RESPONSE REGULATOR receiver
FY142_23685	COG2205	protein histidine kinase activity
FY142_23700	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FY142_23710	COG4774	siderophore transport
FY142_23720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_23725	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_23730	COG1120	ATPase activity
FY142_23735	COG0583	DNA-binding transcription factor activity
FY142_23745	COG3119	arylsulfatase activity
FY142_23750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FY142_23755	COG3842	ATPase activity
FY142_23760	COG0165	Argininosuccinate lyase
FY142_23765	COG0395	ABC-type sugar transport system, permease component
FY142_23770	COG1175	transmembrane transport
FY142_23775	COG2182	Extracellular solute-binding protein
FY142_23780	COG1940	carbohydrate kinase activity
FY142_23805	COG1486	melibiose metabolic process
FY142_23810	COG0747	negative chemotaxis
FY142_23815	COG0601	transmembrane transport
FY142_23820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_23825	COG4172	Belongs to the ABC transporter superfamily
FY142_23830	COG1486	melibiose metabolic process
FY142_23835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FY142_23840	COG0842	Transport permease protein
FY142_23840	COG1129	ABC transporter
FY142_23845	COG0842	Transport permease protein
FY142_23860	COG0784	Response regulator, receiver
FY142_23865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FY142_23875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_23880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FY142_23895	COG0765	amino acid transport
FY142_23905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY142_23915	COG3938	Belongs to the proline racemase family
FY142_23930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_23935	COG0765	amino acid transport
FY142_23940	COG0765	amino acid transport
FY142_23950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FY142_23965	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FY142_23985	COG3383	formate dehydrogenase (NAD+) activity
FY142_23995	COG2223	nitrite transmembrane transporter activity
FY142_24000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY142_24010	COG2186	Transcriptional regulator
FY142_24015	COG0747	negative chemotaxis
FY142_24020	COG0601	transmembrane transport
FY142_24025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_24030	COG4172	Belongs to the ABC transporter superfamily
FY142_24035	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_24045	COG2186	Transcriptional regulator
FY142_24050	COG0747	negative chemotaxis
FY142_24055	COG0601	transmembrane transport
FY142_24060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_24065	COG0405	Gamma-glutamyltransferase
FY142_24075	COG0483	inositol monophosphate 1-phosphatase activity
FY142_24085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FY142_24090	COG0395	ABC-type sugar transport system, permease component
FY142_24110	COG3237	CsbD-like
FY142_24120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY142_24125	COG3181	Tripartite tricarboxylate transporter family receptor
FY142_24130	COG5265	(ABC) transporter
FY142_24135	COG0488	(ABC) transporter
FY142_24160	COG1049	propionate catabolic process, 2-methylcitrate cycle
FY142_24165	COG0110	maltose O-acetyltransferase activity
FY142_24175	COG1063	alcohol dehydrogenase
FY142_24180	COG3284	Transcriptional regulator
FY142_24200	COG1129	ABC transporter
FY142_24205	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_24210	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_24220	COG0572	uridine kinase
FY142_24225	COG1082	Xylose isomerase domain protein TIM barrel
FY142_24250	COG4178	(ABC) transporter
FY142_24290	COG0640	Transcriptional regulator
FY142_24315	COG1192	Involved in chromosome partitioning
FY142_24320	COG1475	DNA binding
FY142_24325	COG0640	Transcriptional regulator
FY142_24340	COG1126	abc transporter atp-binding protein
FY142_24345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY142_24350	COG1609	Transcriptional regulator
FY142_24385	COG3239	Fatty acid desaturase
FY142_24395	COG1278	Cold shock
FY142_24470	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FY142_24470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY142_24505	COG4191	Histidine kinase
FY142_24510	COG1132	(ABC) transporter
FY142_24520	COG0640	Transcriptional regulator
FY142_24550	COG4977	sequence-specific DNA binding
FY142_24555	COG2211	Major facilitator Superfamily
FY142_24560	COG2807	transmembrane transport
FY142_24565	COG1846	Transcriptional regulator
FY142_24580	COG2814	Major facilitator Superfamily
FY142_24610	COG3443	Belongs to the bacterial solute-binding protein 9 family
FY142_24625	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FY142_24630	COG0583	DNA-binding transcription factor activity
FY142_24645	COG0071	Belongs to the small heat shock protein (HSP20) family
FY142_24690	COG3838	Conjugal transfer protein Trbc
FY142_24695	COG3702	type iv secretory pathway
FY142_24700	COG3451	type IV secretory pathway VirB4
FY142_24715	COG3704	protein secretion by the type IV secretion system
FY142_24725	COG3736	Type IV secretory pathway, component VirB8
FY142_24730	COG3504	Conjugal transfer protein
FY142_24735	COG2948	multi-organism process
FY142_24740	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
FY142_24840	COG3831	ATPase activity
FY142_24855	COG3505	Type IV secretory pathway VirD4
FY142_24875	COG0583	DNA-binding transcription factor activity
FY142_24915	COG0745	RESPONSE REGULATOR receiver
FY142_24955	COG3842	ATPase activity
FY142_24960	COG4208	sulfate ABC transporter
FY142_24965	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY142_24985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FY142_24990	COG1942	4-Oxalocrotonate Tautomerase
FY142_25000	COG3971	2-oxopent-4-enoate hydratase activity
FY142_25010	COG1414	Transcriptional regulator
FY142_25020	COG1137	ATPase activity
FY142_25035	COG4177	L-phenylalanine transmembrane transporter activity
FY142_25055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FY142_25060	COG1175	transmembrane transport
FY142_25065	COG0395	ABC-type sugar transport system, permease component
FY142_25075	COG0366	Alpha amylase catalytic
FY142_25080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY142_25085	COG1082	Xylose isomerase domain protein TIM barrel
FY142_25090	COG3842	ATPase activity
FY142_25100	COG1940	carbohydrate kinase activity
FY142_25105	COG0395	ABC-type sugar transport system, permease component
FY142_25115	COG2182	Extracellular solute-binding protein
FY142_25120	COG0673	inositol 2-dehydrogenase activity
FY142_25150	COG1126	abc transporter atp-binding protein
FY142_25155	COG0765	amino acid transport
FY142_25160	COG0765	amino acid transport
FY142_25170	COG4608	Belongs to the ABC transporter superfamily
FY142_25180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_25195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_25200	COG0583	DNA-binding transcription factor activity
FY142_25205	COG2423	ornithine cyclodeaminase activity
FY142_25215	COG1957	nucleoside hydrolase
FY142_25235	COG1335	isochorismatase
FY142_25240	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_25285	COG0583	DNA-binding transcription factor activity
FY142_25290	COG1902	pentaerythritol trinitrate reductase activity
FY142_25295	COG0583	DNA-binding transcription factor activity
FY142_25300	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_25310	COG1335	isochorismatase
FY142_25315	COG0583	DNA-binding transcription factor activity
FY142_25325	COG1695	Transcriptional regulator
FY142_25405	COG2207	Transcriptional regulator
FY142_25450	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_25465	COG1802	Transcriptional regulator
FY142_25470	COG3485	protocatechuate 3,4-dioxygenase
FY142_25475	COG3971	2-oxopent-4-enoate hydratase activity
FY142_25490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FY142_25495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY142_25510	COG1063	alcohol dehydrogenase
FY142_25520	COG1960	acyl-CoA dehydrogenase activity
FY142_25525	COG1024	Enoyl-CoA hydratase
FY142_25535	COG1012	belongs to the aldehyde dehydrogenase family
FY142_25540	COG0477	Major facilitator Superfamily
FY142_25555	COG3706	GGDEF domain
FY142_25575	COG1846	Transcriptional regulator
FY142_25615	COG1012	belongs to the aldehyde dehydrogenase family
FY142_25625	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FY142_25635	COG3386	PFAM SMP-30 Gluconolaconase
FY142_25640	COG3622	Belongs to the hyi family
FY142_25645	COG2084	Dehydrogenase
FY142_25670	COG1940	carbohydrate kinase activity
FY142_25675	COG1172	Belongs to the binding-protein-dependent transport system permease family
FY142_25685	COG1129	ABC transporter
FY142_25705	COG0583	DNA-binding transcription factor activity
FY142_25710	COG2271	Major facilitator Superfamily
FY142_25720	COG2272	Belongs to the type-B carboxylesterase lipase family
FY142_25740	COG1129	ABC transporter
FY142_25765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FY142_25775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FY142_25810	COG0583	DNA-binding transcription factor activity
FY142_25815	COG1414	Transcriptional regulator
FY142_25825	COG4948	Mandelate Racemase Muconate Lactonizing
FY142_25835	COG3842	ATPase activity
FY142_25840	COG1175	transmembrane transport
FY142_25845	COG0395	ABC-type sugar transport system, permease component
FY142_25855	COG0477	Major facilitator Superfamily
FY142_25890	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FY142_25910	COG0747	negative chemotaxis
FY142_25920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_25935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FY142_25945	COG4215	(ABC) transporter
FY142_26000	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FY142_26005	COG0251	oxidation-reduction process
FY142_26010	COG3547	Transposase (IS116 IS110 IS902 family)
FY142_26045	COG1028	Short-chain dehydrogenase reductase Sdr
FY142_26050	COG1335	isochorismatase
FY142_26060	COG1309	transcriptional regulator
FY142_26065	COG4604	ABC transporter, ATP-binding protein
FY142_26070	COG4605	iron ion homeostasis
FY142_26075	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY142_26085	COG2132	Multicopper oxidase
FY142_26090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY142_26095	COG4771	TonB-dependent receptor
FY142_26130	COG1695	Transcriptional regulator
FY142_26165	COG2132	Multicopper oxidase
FY142_26200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY142_26220	COG1192	Involved in chromosome partitioning
FY142_26225	COG1475	DNA binding
FY142_26230	COG0640	Transcriptional regulator
FY142_26235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FY142_26265	COG2211	Major facilitator Superfamily
FY142_26310	COG4974	Belongs to the 'phage' integrase family
FY142_26315	COG1051	belongs to the nudix hydrolase family
FY142_26355	COG1475	DNA binding
FY142_26380	COG2824	Alkylphosphonate utilization operon protein PhnA
FY142_26400	COG1280	lysine exporter protein (LysE YggA)
FY142_26465	COG5489	Protein of unknown function (DUF736)
FY142_26550	COG1283	sodium-dependent phosphate transmembrane transporter activity
FY142_26565	COG0747	negative chemotaxis
FY142_26585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_26590	COG0584	glycerophosphoryl diester phosphodiesterase
FY142_26595	COG0483	inositol monophosphate 1-phosphatase activity
FY142_26660	COG3161	chorismate lyase activity
FY142_26810	COG3436	PFAM IS66 Orf2 family protein
FY142_26905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY142_26935	COG0583	DNA-binding transcription factor activity
FY142_26940	COG0747	negative chemotaxis
FY142_26955	COG0252	asparaginase activity
FY142_26960	COG0583	DNA-binding transcription factor activity
FY142_26980	COG3842	ATPase activity
FY142_27005	COG3701	Conjugal transfer protein
FY142_27010	COG3846	protein secretion by the type IV secretion system
FY142_27020	COG5314	conjugation
FY142_27025	COG3451	type IV secretory pathway VirB4
FY142_27040	COG4962	Type ii secretion system protein e